GeneWiki Entry History Most Recent Version:| Gene Symbol: | CHRNA3 | | Species: | mouse | | Web URL: | http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18227835 | | Entry: | Strong candidate for nicotine dependence in human association studies. In a GWAS study of 14000 (Berrettini et al.), CHRNA3 alleles have a odds ration of 1.3 and a p value of 1.0E-10. deCODE study in 2008 also found high association across a 60 Kb region that includes CHRNA5 and CHRNA3. Expression of alpha3 in amygdala, entorhinal cortex and nucleus accumbens likely to be most important. | | Category: | Genetic variation and alleles; Health and disease associations;
Expression patterns: mature cells, tissues | | Add Time: | 2009-07-15 10:50:21 | | Reason for Modification: | more |
Previous Version:| Gene Symbol: | CHRNA3 | | Species: | mouse | | Entry: | Strong candidate for nicotine dependence in human association studies. In a GWAS study of 14000 (Berrettini et al.), CHRNA3 alleles have a odds ration of 1.3 and a p value of 1.0E-10. deCODE study in 2008 also found high association across a 60 Kb region that includes CHRNA5 and CHRNA3. Expression of alpha3 in amygdala, entorhinal cortex and nucleus accumbens likely to be most important. | | Category: | Genetic variation and alleles; Health and disease associations;
Expression patterns: mature cells, tissues | | Add Time: | 2009-07-15 09:11:29 | | Reason for Modification: | more |
| Gene Symbol: | CHRNA3 | | Species: | mouse | | Entry: | Nominated as candidate for nicotine dependence in human association studies. | | Category: | Health and disease associations | | Add Time: | 2007-08-10 14:06:30 |
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Pjotr Prins,
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