Data Set Group2: UCLA BHHBF2 Muscle (2005) mlratio
| Data Set: UCLA BHHBF2 Muscle Female Only |
| GN Accession: GN187 |
| GEO Series: GSE12795 |
| Title: Expression profiling of Muscle tissue from C57BL/6J X C3H/HeJ)F2 and (C3H/HeJ X C57BL/6J)F2 |
| Organism: Mouse (Mus musculus, mm10) |
| Group: BHHBF2 |
| Tissue: Muscle mRNA |
| Dataset Status: Public |
| Platforms: Agilent Mouse Custom (GPL2510) |
| Normalization: mlratio |
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| Contact Information |
Aldons Lusis
University of California, Los Angeles
UCLA Med-Cardio/Microbio BOX 951679
Los Angeles, CA 90095 USA
Tel. 310 825-1359
jlusis@mednet.ucla.edu
Website
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| Download datasets and supplementary data files |
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| Specifics of this Data Set: |
| Females only
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| Summary: |
| The purpose of this experiment was to determine the expression traits in animals from F2 intercross of inbred strains C57BL/6J, C3H/HeJ. (N=309, 164 males and 145 females).
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| About the cases used to generate this set of data: |
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| About the tissue used to generate this set of data: |
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| About the array platform: |
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| About data values and data processing: |
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| Notes: |
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| Experiment Type: |
| Muscle from 285 F2 female and male mice were generated by intercrossing F1 mice. Mice were fed chow diet containing 4% fat (Ralston-Purina Co., St. Louis, MO) until 8 weeks of age and then were placed on a high-fat "Western" diet containing 42% fat and 0.15% cholesterol (Teklad 88137, Harlan Teklad, Madison WI) for 12 weeks. At 20 weeks mice were sacrificed, after a 12-hour fast Muscle tissues were dissected and flash frozen in LN2 and stored at -80°C. Keywords=Genetics of Gene Expression Keywords Keywords=C57B1/J6 Keywords=C3H/HeJ
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| Contributor: |
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| Citation: |
- Orozco LD, Cokus SJ, Ghazalpour A, Ingram-Drake L et al. Copy number variation influences gene expression and metabolic traits in mice. Hum Mol Genet 2009 Nov 1;18(21):4118-29. PMID: 19648292
- van Nas A, Ingram-Drake L, Sinsheimer JS, Wang SS et al. Expression quantitative trait loci: replication, tissue- and sex-specificity in mice. Genetics2010 Jul;185(3):1059-68. PMID: 20439777
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| Data source acknowledgment: |
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| Study Id: |
58
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