Details and Links

Gene Symbol:		CHRNA3
Aliases:		LNCR2; PAOD2; MGC104879; CHRNA3
Description:		cholinergic receptor, nicotinic, alpha 3
Location:		Chr 15 @ 78.887911 Mb on the minus strand
Target Score:		BLAT specificity: 1.2   Score: 50
Species and Group:		Human, AD-cases-controls-Myers
Database 3:		GSE15222 Human Brain Normal Myers (Apr09) RankInv
Resource Links:		Gene  OMIM  HomoloGene
		BioGPS  STRING  PANTHER  Gemma  ABA  EBI GWAS  Wiki-Pi

Add	Find	Verify	GeneWiki

  Basic Statistics

Include: All Cases AD-cases-controls-Myers Only Non-AD-cases-controls-Myers Only    

Basic Table Probability Plot Bar Graph (by name) Bar Graph (by rank) Box Plot Statistic Value N of Samples 187 Mean 7.114 Median 7.053 Standard Error (SE) 0.023 Standard Deviation (SD) 0.312 Minimum 6.720 Maximum 8.803 Range (log2) 2.083 Range (fold) 4.237 Interquartile Range 1.204 This plot evaluates whether data are normally distributed. Different symbols represent different groups. More about Normal Probability Plots and more about interpreting these plots from the glossary More about Box Plots Basic Table Probability Plot Bar Graph (by name) Bar Graph (by rank) Box Plot Statistic Value N of Samples 185 Mean 7.114 Median 7.053 Standard Error (SE) 0.023 Standard Deviation (SD) 0.313 Minimum 6.720 Maximum 8.803 Range (log2) 2.083 Range (fold) 4.237 Interquartile Range 1.204 This plot evaluates whether data are normally distributed. Different symbols represent different groups. More about Normal Probability Plots and more about interpreting these plots from the glossary More about Box Plots Fewer than 4 non-AD-cases-controls-Myers case data were entered. No statistical analysis has been attempted.

  Calculate Correlations

Sample r Literature r Tissue r Database: AD-cases-controls-Myers Published Phenotypes AD-cases-controls-Myers GSE15222 Human Brain All Cases Myers (Apr09) RankInv GSE15222 Human Brain Normal Myers (Apr09) RankInv GSE15222 Human Brain Alzheimer Myers (Apr09) RankInv Return: top 25 top 50 top 100 top 200 top 500 top 1000 top 2000 top 5000 top 10000 top 15000 top 20000 top 30000 top 40000 top 60000 Samples: AD-cases-controls-Myers Only Non-AD-cases-controls-Myers Only All Cases Pearson    Spearman Rank The Sample Correlation is computed between trait data and any other traits in the sample database selected above. Use Spearman Rank when the sample size is small (<20) or when there are influential outliers. Database: AD-cases-controls-Myers Published Phenotypes AD-cases-controls-Myers GSE15222 Human Brain All Cases Myers (Apr09) RankInv GSE15222 Human Brain Normal Myers (Apr09) RankInv GSE15222 Human Brain Alzheimer Myers (Apr09) RankInv Return: top 25 top 50 top 100 top 200 top 500 top 1000 top 2000 top 5000 top 10000 top 15000 top 20000 top 30000 top 40000 top 60000 Samples: AD-cases-controls-Myers Only Non-AD-cases-controls-Myers Only All Cases The Literature Correlation (Lit r) between this gene and all other genes is computed using the Semantic Gene Organizer and human, rat, and mouse data from PubMed. Values are ranked by Lit r, but Sample r and Tissue r are also displayed. More on using Lit r Database: AD-cases-controls-Myers Published Phenotypes AD-cases-controls-Myers GSE15222 Human Brain All Cases Myers (Apr09) RankInv GSE15222 Human Brain Normal Myers (Apr09) RankInv GSE15222 Human Brain Alzheimer Myers (Apr09) RankInv Return: top 25 top 50 top 100 top 200 top 500 top 1000 top 2000 top 5000 top 10000 top 15000 top 20000 top 30000 top 40000 top 60000 Samples: AD-cases-controls-Myers Only Non-AD-cases-controls-Myers Only All Cases Pearson    Spearman Rank The Tissue Correlation (Tissue r) estimates the similarity of expression of two genes or transcripts across different cells, tissues, or organs (glossary). Tissue correlations are generated by analyzing expression in multiple samples usually taken from single cases. Pearson and Spearman Rank correlations have been computed for all pairs of genes using data from mouse samples.

  Mapping Tools

mappingMethodId 2 has not been implemented for this dataset yet.

  Review and Edit Data

Edit or delete values in the Trait Data boxes, and use the Reset option as needed.   Block samples by index:         AD-cases-controls-Myers Only Non-AD-cases-controls-Myers Only       Block samples by group:      Status Sex Age       None Live UTHSC Cryo Ext Cyro Normal Alzheimer's N AD CIE AIR None F M Male Female None 200 500 800 63 85 80 102 79 76 83 88 82 69 78 86 93 84 91 73 81 75 70 77 72 95 87 68 74 94 96 97 90 67 66 65 99 100 71 89 101 92 98 x 5.25 4 4.25 4.75 3.25 216 768 840 2 3 48 180 13 12 444 156 360 228 252 15 480 276 264 24 432 8.75 984 5.5 19 36 132 660 504 9.25 489 650 756 492 495 367 433 566 323 448 477 394 456 483 609 526 460 471 631 457 536 741 506 561 606 850 605 455 475 493 548 551 537 502 596 675 462 512 415 470 636 639 430 454 709 472 543 445 467 648 464 662 683 414 549 554 748 446 530 661 451 614 633 728 486 518 616 419 438 564 499 740 479 608 778 487 407 621 528 587 766 501 694 734 759 702 353 439 699 972 425 601 808 389 715 463 557 649 421 623 558 602 458 761 474 701 582 544 642 443 710 804 535 408 579 347 659 485 515 704 434 441 612 617 484 522 592 613 478 442 666 452 488 524 507 577 490 223 45 28 34 44 37 64 21 40 52 26 20 30 33 22 42 47 60 50 1109 995 953 940 925 896 882 838 795 784 764 743 739 737 711 705 581 397 359 215 182 1004 878 774 749 742 726 724 720 719 708 684 676 657 655 637 586 572 547 498 351 207 128 908 847 845 814 712 670 622 590 532 398 344 338 212 816 700 667 645 607 585 550 521 509 361 912 880 879 856 640 552 364 193 626 619 450 447 342 996 791 744 690 641 545 370 210 1161 1114 1107 986 898 865 692 540 371 214 862 697 681 638 604 318 143 687 686 615 611 600 529 459 324 224 181 805 672 658 956 680 625 576 570 476 466 440 435 427 403 401 393 348 337 245 688 593 517 503 437 388 349 265 243 242 762 426 1197 773 717 244 1229 1117 1108 1088 695 271 362 355 204 195 174 153 152 449 380 248 226 187 140 136 815 788 653 603 340 261 799 644 595 594 568 533 424 685 198 412 406 352 852 779 630 520 835 730 635 628 620 538 511 855 829 703 677 560 553 390 377 205 841 689 527 409 368 320 312 1083 849 787 698 646 883 583 563 387 280 190 911 785 747 729 902 860 796 738 599 574 431 385 225 867 826 757 750 736 722 674 369 333 963 886 839 821 691 665 386 363 345 723 721 673 656 539 365 357 209 201 820 725 584 197 285 491 350 949 824 811 751 578 469 284 267 172 618 516 510 358 346 321 291 262 254 202 976 922 381 376 713 678 654 236 379 240 627 384 1053 948 731 663 643 405 188 647 569 556 555 508 496 453 302 189 167 881 806 745 632 565 436 303 233 161 772 727 696 597 573 983 959 848 793 575 269 268 211 718 571 733 833 812 257 218 541 944 899 861 777 392 251 235 634 374 297 891 877 834 810 754 525 253 682 410 343 259 752 889 776 186 366 938 931 928 921 798 275 222 230 1017 854 807 794 760 755 732 598 559 505 354 327 278 241 184 108 716 927 920 765 735 1242 885 893 875 780 679 652 562 308 274 157 771 763 939 901 827 758 239 664 383 897 206 1015 935 909 497 237 951 950 937 900 832 802 753 624 154 831 588 706 1018 979 968 842 542 923 589 513 468 378 330 325 293 288 217 335 287 263 177 171 917 916 404 220 997 870 610 591 1010 943 914 884 746 294 858 846 481 227 1002 797 790 234 668 978 836 792 781 873 825 279 423 391 1072 1064 1050 965 851 213 531 395 118 895 822 819 567 176 144 892 400 971 957 372 1131 1100 1039 714 546 514 183 942 905 843 823 874 461 482 307 141 669 629 519 322 828 907 465 332 1080 992 133 314 196 331 334 973 1068 1122 974 918 1250 1046 1025 857 890 947 817 1033 946 930 962 981 775 1092 1006 967 932 1079 1024 1016 955 283 229 1091 1065 1040 941 316 651 258 429 1044 57 1252 954 103 924 910 866 988 876 416 310 135 767 306 178 266 809 1038 1054 863 1007 693 328 769 837 830 1001 801 232 309 770 869 402 356 813 1049 305 373 853 789 786 906 336 473 523 155 246 417 975 1003 844 1005 782 1051 580 913 887 903 803 219 1034 238 413 1077 1099 1070 1090 1008 1112 292 1000 994 936 919 1144 933 1012 868 1106 1168 1028 1022 929 1163 1019 1067 969 1043 961 1030 1169 1084 277 894 1143 960 1103 1101 1212 1201 1035 273 915 1203 859 1063 1031 1075 1055 966 315 970 990 1119 1097 1056 1037 926 999 1094 1020 818 864 1111 1057 1185 1086 1156 170 1093 871 299 904 295 671 1071 1042 420 888 982 1009 1073 707 534 1188 1021 1216 1060 1052 998 1078 952 993 1313 1282 1076 1145 977 418 1243 1134 1214 985 872 1165 991 1110 1159 1226 1276 1029 1162 428 1184 958 1105 1196 1297 1013 1232 1220 1141 1286 1014 1085 1360 1062 1124 1231 1256 1058 1170 1142 1047 319 1098 1234 1116 1136 1027 1350 1115 1011 51 1200 53 46 250 1137 1081 934 1129 1189 1140 989 1096 1263 105 1066 382 783 249 1154 1036 1164 1113 260 1190 1280 1328 1320 298 1087 1130 1270 1183 1385 203 1209 148 980 1351 1182 1199 1167 1261 1259 1032 1155 1026 1227 1322 1023 1210 396 1284 1125 1095 1193 1118 270 1290 1354 311 1148 1380 1158 1151 1082 1215 1222 1177 1357 987 1128 1306 1126 1251 1074 272 1123 1133 1048 1340 282 326 1240 1211 1246 1223 1192 945 1139 1153 1337 286 1374 494 1194 1147 1127 964 1041 1204 1205 1135 300 1121 1272 1172 1260 1217 1174 1239 1061 1278 1339 1291 1344 1327 304 1157 1236 1069 313 1059 1338 1315 1317 1138 1412 1264 1271 375 1045 1166 1224 1237 1283 1173 175 1219 1274 1176 1191 1305 1089 1104 1249 162 1120 1267 1225 1178 281 1146 1202 1175 1186 1213 422 1195 1303 1171 1257 1235 1221 1245 1102 1266 1399 165 1160 1149 1132 1254 1230 1152 1248 1273 329 1258 1179 1295 1208 1268 1187 1294 1288 1206 290 1150 149 339 1181 194 1325 1255 1359 1464 1285 1292 1289 1238 1281 1389 185 1228 1423 1314 1218 1361 1253 1233 1180 1318 1323 1287 301 1275 1269 1298 1302 1348 1265 1373 1316 1371 1198 1353 1413 1363 1310 1456 150 1376 256 1332 134 27 123 1262 137 1324 1244 1247 247 1304 317 1241 1321 1301 1379 179 255 411 1375 1384 1447 1330 1367 341 399 164 208 1358 1207 1311 1277 289 125 296 1345 121 1341 231 117 1364 1319 191 1366 163 1293 1329 1396 1300 107 1342 1309 1326 1395 1334 1333 1343 1393 199 1369 147 139 124 110 116 39 23 31 192 120 109 131 112 111 127 104 173 166 129 115 146 138 169 54 130 122 119 126 58 56 158 159 35 221         Options:                          Outliers highlighted in  yellow  can be hidden using the Hide Outliers button,   and samples with no value (x) can be hidden by clicking Hide No Value . Index Sample Value Status Sex Age 1 C388327F85A AD M 85 2 C388352M84A AD M 84 3 C388356M80A AD M 80 4 C388357M81A AD M 81 5 C388353F91A AD F 91 6 C388338F80A AD F 80 7 C388351F84A AD F 84 8 C388337M75A AD M 75 9 C388309M82A AD M 82 10 C388336F85A AD F 85 11 C388242M87A AD M 87 12 C388238F75A AD F 75 13 C388394M86A AD M 86 14 C388272F73A AD F 73 15 C388222F102A AD F 102 16 C388245M91A AD M 91 17 C388237M89A AD M 89 18 C388236M89A AD M 89 19 C388239F80A AD F 80 20 C388240M81A AD M 82 21 C388229M93A AD M 93 22 C388391F82A AD F 82 23 C388228F93A AD F 93 24 C388220F95A AD F 95 25 C388235M84A AD M 84 26 C388393M83A AD M 83 27 C388389M75A AD M 75 28 C388243F90A AD F 90 29 C388392F73A AD F 73 30 C388294M84A AD M 84 31 C388221F98A AD F 98 32 C388244F90A AD F 90 33 C388241F97A AD F 97 34 C388218F101A AD F 101 35 C388395F87A AD F 87 36 C388230F94A AD F 94 37 C388385M77A AD M 77 38 C388383F90A AD F 90 39 C388384F88A AD F 88 40 C388302M73A AD M 73 41 C388303F89A AD F 89 42 C388285M86A AD M 86 43 C388298M71A AD M 71 44 C388287M82A AD M 82 45 C388288M78A AD M 78 46 C388314F81A AD F 81 47 C388304F82A AD F 82 48 C388315F86A AD M 86 49 C388316M89A AD M 89 50 C388317F73A AD F 73 51 C388301F84A AD F 84 52 C388310F75A AD F x 53 C388358F87A AD F 87 54 C388359M85A AD M 85 55 C388360F90A AD F 90 56 C388361M79A AD M 79 57 C388326F86A AD F 86 58 C388325M77A AD M 77 59 C388319M73A AD M 73 60 C388374F83A AD F 83 61 C388320M81A AD M 81 62 C388259M74A AD M 74 63 C388321F84A AD F 84 64 C388331M79A AD M 79 65 C388372F80A AD F 80 66 C388373M83A AD M 83 67 C388289M79A AD M 79 68 C388290F84A AD F 84 69 C388291F87A AD F 87 70 C388292F86A AD F 86 71 C388362F87A AD F 87 72 C388363M75A AD M 75 73 C388364F92A AD F 92 74 C388323F82A AD F 82 75 C388324M76A AD M 76 76 C388332M81A AD M 81 77 C388330M81A AD M 81 78 C388264M80A AD M 80 79 C388265M84A AD M 84 80 C388254M81A AD M 81 81 C388255F68A AD F 68 82 C388340F82A AD F 82 83 C388341M82A AD M 82 84 C388342M77A AD M 77 85 C388246M78A AD M 78 86 C388247F80A AD F 80 87 C388375F84A AD F 84 88 C388248F79A AD F 79 89 C388249F87A AD F 87 90 C388262M83A AD M 83 91 C388263M83A AD M 83 92 C388311M88A AD M 88 93 C388256F81A AD F 81 94 C388257F82A AD F 82 95 C388322F93A AD F 93 96 C388277F92A AD F 92 97 C388260M88A AD M 88 98 C388278F78A AD F 78 99 C388279F94A AD F 94 100 C388369M82A AD M 82 101 C388371F81A AD M 81 102 C388269F81A AD F 81 103 C388270F79A AD F 79 104 C388271M74A AD M 74 105 C388217F97A AD F 97 106 C388370M76A AD M 76 107 C388295M83A AD M 83 108 C388296M81A AD M 81 109 C388297F93A AD F 93 110 C388286M77A AD M 77 111 C388299M78A AD M 78 112 C388300F75A AD F 75 113 C388386F80A AD F 80 114 C388387M87A AD M 87 115 C388388M86A AD M 86 116 C388382M84A AD M 84 117 C388365F84A AD F 84 118 C388366M75A AD M 75 119 C388367F76A AD F 76 120 C388368F86A AD F 86 121 C388345F96A AD F 96 122 C388347M86A AD M 86 123 C388312M77A AD M 77 124 C388313M85A AD M 85 125 C388333F78A AD F 78 126 C388233M75A AD M 75 127 C388234M92A AD M 92 128 C388355F84A AD F 84 129 C388232F90A AD F 90 130 C388261F78A AD F 78 131 C388306M83A AD M 83 132 C388397M83A AD M 83 133 C388339F97A AD F 97 134 C388350F90A AD F 90 135 C388348M88A AD M 88 136 C388396M78A AD M 78 137 C388354F81A AD F 81 138 C388390F86A AD F 86 139 C388305M69A AD M 69 140 C388266F79A AD F 79 141 C388231F87A AD F 87 142 C388223M87A AD M 87 143 C388349F90A AD F 90 144 C388318F96A AD F 96 145 C388328M83A AD M 83 146 C388329M76A AD M 76 147 C388334M80A AD M 80 148 C388335M84A AD M 84 149 C388308F86A AD F 86 150 C388219M84A AD M 84 151 C388274F86A AD F 86 152 C388275F86A AD F 86 153 C388273M87A AD M 87 154 C388276F87A AD F 87 155 C388226M84A AD M 84 156 C388307M71A AD M 71 157 C388282M76A AD M 76 158 C388258M78A AD M 78 159 C388281F94A AD F 94 160 C388284M91A AD F 91 161 C388268M92A AD M 92 162 C388377F92A AD M 92 163 C388251M86A AD M 86 164 C388380M83A AD M 83 165 C388381M79A AD M 79 166 C388225M87A AD M 87 167 C388253F72A AD F 72 168 C388267F86A AD F 86 169 C388376M93A AD M 93 170 C388224F77A AD F 77 171 C388343M81A AD M 81 172 C388250F88A AD F 88 173 C388378M78A AD M 78 174 C388379M90A AD M 90 175 C388252F74A AD F 74 176 C388346F90A AD F 90 177 C225652M85N N M 85 178 C225662M85N N M 85 179 C225664M79N N M 79 180 C225665F85N N F 85 181 C225666F73N N F 73 182 C225667M81N N M 81 183 C225668M79N N M 79 184 C225669M77N N M 77 185 C225670M69N N M 69 186 C225671M86N N M 86 187 C225672F83N N F 83 188 C225673M78N N M 78 189 C225674M94N N M 94 190 C225675F81N N F 81 191 C225676M76N N M 76 192 C225677M83N N M 83 193 C225678M68N N M 68 194 C225679F82N N F 82 195 C225680F70N N F 70 196 C225681M86N N M 86 197 C225682M78N N M 78 198 C225683M82N N M 82 199 C225684F94N N F 94 200 C225685F87N N F 87 201 C225686M74N N M 74 202 C225687M85N N M 85 203 C225688M75N N M 75 204 C225689F86N N F 86 205 C225690M75N N M 75 206 C225691M81N N M 81 207 C225692F72N N F 72 208 C225693F81N N F 81 209 C225695M81N N M 81 210 C225696M81N N M 81 211 C225697M91N N M 91 212 C225698M84N N M 84 213 C225699M96N N M 96 214 C225700F97N N F 97 215 C225701M90N N M 90 216 C225702F67N N F 67 217 C225703F83N N F 83 218 C225704F82N N F 82 219 C225705F66N N F 66 220 C225706F72N N F 72 221 C225707F65N N F 65 222 C225708F75N N F 75 223 C225709F74N N F 74 224 C225711M68N N M 68 225 C225713F80N N F 80 226 C225714M80N N M 80 227 C225715M66N N M 66 228 C225717M88N N M 88 229 C225718F91N N F 91 230 C225719M73N N M 73 231 C225720M76N N M 76 232 C225721M75N N M 75 233 C225722F86N N F 86 234 C225723F72N N F 72 235 C225724M97N N M 97 236 C225725M86N N M 86 237 C225726M82N N M 82 238 C225727F95N N F 95 239 C225728F76N N F 76 240 C225729M76N N M 76 241 C225730M69N N M 69 242 C225731F80N N F 80 243 C225732F99N N F 99 244 C225733M68N N M 68 245 C225734M70N N M 70 246 C225735F87N N F 87 247 C225736F99N N M 99 248 C225737F88N N F 88 249 C225739M65N N M 65 250 C225741M82N N M 82 251 C225742F78N N F 78 252 C225743F85N N F 85 253 C225744F100N N F 100 254 C225745F87N N F 87 255 C225746F85N N F 85 256 C225747F97N N F 97 257 C225748M65N N M 65 258 C225749M65N N M 65 259 C225751F87N N F 87 260 C225752F85N N F 85 261 C225753M68N N M 68 262 C225754M71N N M 71 263 C225755F83N N F 83 264 C225756M76N N M 76 265 C225757M67N N M 67 266 C225758F100N N F 100 267 C225759M79N N M 79 268 C225760M74N N M 74 269 C225761F88N N F 88 270 C225762M70N N M 70 271 C225763F97N N F 97 272 C225764M69N N M 69 273 C225915F99N N F 99 274 C225916M81N N M 81 275 C225917F85N N F 85 276 C225918F82N N F 82 277 C225919M70N N M 70 278 C225920M73N N M 73 279 C225921M83N N M 83 280 C225922M74N N M 74 281 C225923M77N N M 77 282 C225924M81N N M 81 283 C225925M65N N M 65 284 C225926F73N N F 73 285 C225927F85N N F 85 286 C225928M69N N M 69 287 C225929M72N N M 72 288 C225930F76N N F 76 289 C225931M73N N M 73 290 C225932M66N N M 66 291 C225933F85N N F 85 292 C225934M87N N M 87 293 C225935F86N N F 86 294 C225936F73N N F 73 295 C225937M86N N M 86 296 C225938M72N N M 72 297 C225939F69N N F 69 298 C225940F88N N M 88 299 C225941M77N N M 77 300 C225942M96N N M 96 301 C225943F78N N F 78 302 C225944M77N N M 77 303 C225945F99N N F 99 304 C225946M78N N M 78 305 C225947F76N N F 76 306 C225948M78N N M 78 307 C225949F97N N F 97 308 C225950F86N N F 86 309 C225951M77N N M 77 310 C225952M87N N M 87 311 C225953F72N N F 72 312 C225954F91N N F 91 313 C225955F85N N F 85 314 C225956M88N N M 88 315 C225957F86N N F 86 316 C225958F93N N F 93 317 C225959M82N N M 82 318 C225961F72N N F 72 319 C225962F85N N F 85 320 C225963M70N N F 70 321 C225964F67N N M 67 322 C225965F74N N F 74 323 C226034M69N N M 69 324 C226035M85N N M 85 325 C226037M89N N M 89 326 C226038M86N N M 86 327 C226039M90N N M 90 328 C226040F94N N F 94 329 C226041F91N N F 91 330 C226042F91N N F 91 331 C226044F95N N F 95 332 C226045F95N N F 95 333 C226046F91N N F 91 334 C226047M80N N M 80 335 C226048M83N N M 83 336 C226049M67N N M 67 337 C226050M76N N M 76 338 C226051F86N N F 86 339 C226052F86N N F 86 340 C226053M83N N M 83 341 C226055M84N N M 84 342 C226056M80N N M 80 343 C226082M72N N M 72 344 C226145M67N N M 67 345 C226146F96N N F 96 346 C226147F75N N F 75 347 C226148F89N N F 89 348 C226149F86N N F 86 349 C226150M67N N M 67 350 C226151M77N N M 77 351 C226154M65N N M 65 352 C226155M69N N M 69 353 C226156M84N N M 84 354 C226157F85N N F 85 355 C226158M94N N M 94 356 C226159F89N N F 89 357 C226160M87N N M 87 358 C226162M90N N M 90 359 C226163F88N N F 88 360 C226164M94N N M 94 361 C226165F86N N F 86 362 C226167F93N N F 93   Index Sample Value Status Sex Age 1 C225664F79N 2 C226168M91N N M 91