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Trait Data and Analysis  for Record ID 1452010_at

  Details and Links

Gene Symbol: Chrna3
Aliases: (a)3; A730007P14Rik; Acra-3; Acra3; LNCR2; PAOD2; MGC104879; CHRNA3
Description: cholinergic receptor, nicotinic, alpha polypeptide 3; last two exons and proximal 3' UTR
Location: Chr 9 @ 55.012583 Mb on the minus strand
Target Score: BLAT specificity: 11.7   Score: 233  
Species and Group: Mouse, NZBXFVB-N2
Database 3: NCI Mammary M430v2 (Apr09) RMA
Resource Links: Gene  OMIM  UniGene  GenBank  HomoloGene  
UCSC  BioGPS  STRING  PANTHER  Gemma  ABA  EBI GWAS  Wiki-Pi  

Add To Collection Find similar expression data  Check probe locations at UCSC  Write or review comments about this gene  View SNPs and Indels  Check sequence of probes
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  Basic Statistics

Include:    

StatisticValue
N of Samples66
Mean7.103
Median7.105
Standard Error (SE)0.021
Standard Deviation (SD)0.169
Minimum6.727
Maximum7.678
Range (log2)0.951
Range (fold)1.933
Interquartile Range1.157

nP_VzvJTnps.gif


This plot evaluates whether data are normally distributed. Different symbols represent different groups.

More about Normal Probability Plots and more about interpreting these plots from the glossary

Box_hDcCNoAI.gif

More about Box Plots

Bar_bijDbwpg.gif

Bar_8efH7PZa.gif

StatisticValue
N of Samples65
Mean7.104
Median7.110
Standard Error (SE)0.021
Standard Deviation (SD)0.170
Minimum6.727
Maximum7.678
Range (log2)0.951
Range (fold)1.933
Interquartile Range1.166

nP_UViQiUpw.gif


This plot evaluates whether data are normally distributed. Different symbols represent different groups.

More about Normal Probability Plots and more about interpreting these plots from the glossary

Box_ZBK0yNUi.gif

More about Box Plots

Bar_AVRHlUzX.gif

Bar_GUZMwN34.gif

Fewer than 4 non-NZBXFVB-N2 case data were entered. No statistical analysis has been attempted.

  Calculate Correlations

Database:
Return:
Samples:

Pearson    Spearman Rank



The Sample Correlation is computed between trait data and any
other traits in the sample database selected above. Use Spearman Rank
when the sample size is small (<20) or when there are influential outliers.
Database:
Return:
Samples:



The Literature Correlation (Lit r) between this gene and all other genes is computed
using the Semantic Gene Organizer and human, rat, and mouse data from PubMed.
Values are ranked by Lit r, but Sample r and Tissue r are also displayed.

More on using Lit r
Database:
Return:
Samples:

Pearson    Spearman Rank



The Tissue Correlation (Tissue r) estimates the similarity of expression of two genes
or transcripts across different cells, tissues, or organs (glossary). Tissue correlations
are generated by analyzing expression in multiple samples usually taken from single cases.
Pearson and Spearman Rank correlations have been computed for all pairs of genes
using data from mouse samples.

  Mapping Tools

Chromosome:
Mapping Scale:
Permutations:

Bootstrap Test (n=2000)
Use Parents
Use Weighted



Interval Mapping computes linkage maps for the entire genome or single
chromosomes. The Permutation Test estimates suggestive and significant
linkage scores. The Bootstrap Test estimates the precision of the QTL location.

Display LRS above:
Permutations:

Display all LRS
Use Parents
Use Weighted



Marker regression computes and displays LRS values for individual markers.
This function also lists additive effects (phenotype units per allele) and
dominance deviations for some datasets.

Chromosome:
Mapping Scale:
Control Locus:
Permutations:

Bootstrap Test (n=2000)
Use Parents



Composite Interval Mapping allows you to control for a single marker as
a cofactor. To find a control marker, run the Marker Regression function.

Sort by:
Return:

Permutation Test (n=500)



Pair-Scan searches for pairs of chromosomal regions that are
involved in two-locus epistatic interactions.

  Review and Edit Data

Edit or delete values in the Trait Data boxes, and use the Reset option as needed.

  Block samples by index:            
  Options:                       


  Outliers highlighted in  yellow  can be hidden using the Hide Outliers button,
  and samples with no value (x) can be hidden by clicking Hide No Value .


IndexSampleValue
1 NZB2421
2 NZB2424
3 NZB2426
4 NZB2703
5 NZB3001
6 NZB3004
7 NZB3039
8 NZB3042
9 NZB3046
10 NZB3047
11 NZB3053
12 NZB3197
13 NZB3199
14 NZB3289
15 NZB3290
16 NZB3291
17 NZB3295
18 NZB3296
19 NZB3299
20 NZB3351
21 NZB3353
22 NZB3355
23 NZB3394
24 NZB3397
25 NZB3546
26 NZB3547
27 NZB3548
28 NZB3550
29 NZB3551
30 NZB3567
31 NZB3568
32 NZB3569
33 NZB3570
34 NZB3572
35 NZB3738
36 NZB3739
37 NZB3769
38 NZB3824
39 NZB3825
40 NZB3827
41 NZB3830
42 NZB3852
43 NZB3853
44 NZB3854
45 NZB3855
46 NZB3864
47 NZB3867
48 NZB3868
49 NZB3890
50 NZB3891
51 NZB4946
52 NZB4950
53 NZB4955
54 NZB4956
55 NZB4957
56 NZB4958
57 NZB4960
58 NZB4963
59 NZB4964
60 NZB4966
61 NZB4967
62 NZB4971
63 NZB4973
64 NZB4974
65 NZB4975
66 NZB4977
67 NZB4978
68 NZB4979
69 NZB4980
70 NZB5000
 
IndexSampleValue
1 NZB5000

CITG Web services initiated January, 1994 as Portable Dictionary of the Mouse Genome; June 15, 2001 as WebQTL; and Jan 5, 2005 as GeneNetwork. This site is currently operated by Rob Williams, Pjotr Prins, Zachary Sloan, Arthur Centeno. Design and code by Pjotr Prins, Zach Sloan, Arthur Centeno, Danny Arends, Christian Fischer, Sam Ockman, Lei Yan, Xiaodong Zhou, Christian Fernandez, Ning Liu, Rudi Alberts, Elissa Chesler, Sujoy Roy, Evan G. Williams, Alexander G. Williams, Kenneth Manly, Jintao Wang, and Robert W. Williams, colleagues. Python Powered Registered with Nif
GeneNetwork support from:
  • The UT Center for Integrative and Translational Genomics
  • NIGMS Systems Genetics and Precision Medicine project (R01 GM123489, 2017-2021)
  • NIDA NIDA Core Center of Excellence in Transcriptomics, Systems Genetics, and the Addictome (P30 DA044223, 2017-2022)
  • NIA Translational Systems Genetics of Mitochondria, Metabolism, and Aging (R01AG043930, 2013-2018)
  • NIAAA Integrative Neuroscience Initiative on Alcoholism (U01 AA016662, U01 AA013499, U24 AA013513, U01 AA014425, 2006-2017)
  • NIDA, NIMH, and NIAAA (P20-DA 21131, 2001-2012)
  • NCI MMHCC (U01CA105417), NCRR, BIRN, (U24 RR021760)
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