Details and Links

Gene Symbol:		CHRNA3
Aliases:		CHRNA3
Description:		cholinergic receptor, nicotinic, alpha 3
Location:		Chr 15 @ 76.672451 Mb on the minus strand
Target Score:
Species and Group:		Human, Aging-Brain-UCI
Database 3:		GSE11882 UCI Human Entorhinal Cortex Affy U133 Plus2 (Sep13) RMA
Resource Links:		Gene  OMIM  UniGene  GenBank  HomoloGene
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  Basic Statistics

Basic Table Probability Plot Bar Graph (by name) Bar Graph (by rank) Box Plot Statistic Value N of Samples 39 Mean 7.383 Median 7.349 Standard Error (SE) 0.044 Standard Deviation (SD) 0.274 Minimum 6.965 Maximum 8.411 Range (log2) 1.446 Range (fold) 2.725 Interquartile Range 1.219 This plot evaluates whether data are normally distributed. Different symbols represent different groups. More about Normal Probability Plots and more about interpreting these plots from the glossary More about Box Plots

  Calculate Correlations

Sample r Literature r Tissue r Database: Aging-Brain-UCI Published Phenotypes GSE11882 UCI Human Entorhinal Cortex Affy U133 Plus2 (Sep13) RMA GSE11882 UCI Human Hippocampus Affy U133 Plus2 (Sep13) RMA GSE11882 UCI Human Postcentral Gyrus Affy U133 Plus2 (Sep13) RMA GSE11882 UCI Human Superior Frontal Gyrus Affy U133 Plus2 (Sep13) RMA Return: top 25 top 50 top 100 top 200 top 500 top 1000 top 2000 top 5000 top 10000 top 15000 top 20000 top 30000 top 40000 top 60000 Pearson    Spearman Rank The Sample Correlation is computed between trait data and any other traits in the sample database selected above. Use Spearman Rank when the sample size is small (<20) or when there are influential outliers. Database: Aging-Brain-UCI Published Phenotypes GSE11882 UCI Human Entorhinal Cortex Affy U133 Plus2 (Sep13) RMA GSE11882 UCI Human Hippocampus Affy U133 Plus2 (Sep13) RMA GSE11882 UCI Human Postcentral Gyrus Affy U133 Plus2 (Sep13) RMA GSE11882 UCI Human Superior Frontal Gyrus Affy U133 Plus2 (Sep13) RMA Return: top 25 top 50 top 100 top 200 top 500 top 1000 top 2000 top 5000 top 10000 top 15000 top 20000 top 30000 top 40000 top 60000 The Literature Correlation (Lit r) between this gene and all other genes is computed using the Semantic Gene Organizer and human, rat, and mouse data from PubMed. Values are ranked by Lit r, but Sample r and Tissue r are also displayed. More on using Lit r Database: Aging-Brain-UCI Published Phenotypes GSE11882 UCI Human Entorhinal Cortex Affy U133 Plus2 (Sep13) RMA GSE11882 UCI Human Hippocampus Affy U133 Plus2 (Sep13) RMA GSE11882 UCI Human Postcentral Gyrus Affy U133 Plus2 (Sep13) RMA GSE11882 UCI Human Superior Frontal Gyrus Affy U133 Plus2 (Sep13) RMA Return: top 25 top 50 top 100 top 200 top 500 top 1000 top 2000 top 5000 top 10000 top 15000 top 20000 top 30000 top 40000 top 60000 Pearson    Spearman Rank The Tissue Correlation (Tissue r) estimates the similarity of expression of two genes or transcripts across different cells, tissues, or organs (glossary). Tissue correlations are generated by analyzing expression in multiple samples usually taken from single cases. Pearson and Spearman Rank correlations have been computed for all pairs of genes using data from mouse samples.

  Mapping Tools

Mapping options are disabled for data not matched with genotypes.

  Review and Edit Data

Edit or delete values in the Trait Data boxes, and use the Reset option as needed.   Block samples by index:           Block samples by group:      Tissue Sex Age       None MUS Entorhinal Cortex Hippocampus Medial Temporal Gyrus Posterior Cingulate Superior Frontal Gyrus Primary Visual Cortex VFC SG None F M Male Female None 200 500 800 63 85 80 102 79 76 83 88 82 69 78 86 93 84 91 73 81 75 70 77 72 95 87 68 74 94 96 97 90 67 66 65 99 100 71 89 101 92 98 x 5.25 4 4.25 4.75 3.25 216 768 840 2 3 48 180 13 12 444 156 360 228 252 15 480 276 264 24 432 8.75 984 5.5 19 36 132 660 504 9.25 489 650 756 492 495 367 433 566 323 448 477 394 456 483 609 526 460 471 631 457 536 741 506 561 606 850 605 455 475 493 548 551 537 502 596 675 462 512 415 470 636 639 430 454 709 472 543 445 467 648 464 662 683 414 549 554 748 446 530 661 451 614 633 728 486 518 616 419 438 564 499 740 479 608 778 487 407 621 528 587 766 501 694 734 759 702 353 439 699 972 425 601 808 389 715 463 557 649 421 623 558 602 458 761 474 701 582 544 642 443 710 804 535 408 579 347 659 485 515 704 434 441 612 617 484 522 592 613 478 442 666 452 488 524 507 577 490 223 45 28 34 44 37 64 21 40 52 26 20 30 33 22 42 47 60 50 1109 995 953 940 925 896 882 838 795 784 764 743 739 737 711 705 581 397 359 215 182 1004 878 774 749 742 726 724 720 719 708 684 676 657 655 637 586 572 547 498 351 207 128 908 847 845 814 712 670 622 590 532 398 344 338 212 816 700 667 645 607 585 550 521 509 361 912 880 879 856 640 552 364 193 626 619 450 447 342 996 791 744 690 641 545 370 210 1161 1114 1107 986 898 865 692 540 371 214 862 697 681 638 604 318 143 687 686 615 611 600 529 459 324 224 181 805 672 658 956 680 625 576 570 476 466 440 435 427 403 401 393 348 337 245 688 593 517 503 437 388 349 265 243 242 762 426 1197 773 717 244 1229 1117 1108 1088 695 271 362 355 204 195 174 153 152 449 380 248 226 187 140 136 815 788 653 603 340 261 799 644 595 594 568 533 424 685 198 412 406 352 852 779 630 520 835 730 635 628 620 538 511 855 829 703 677 560 553 390 377 205 841 689 527 409 368 320 312 1083 849 787 698 646 883 583 563 387 280 190 911 785 747 729 902 860 796 738 599 574 431 385 225 867 826 757 750 736 722 674 369 333 963 886 839 821 691 665 386 363 345 723 721 673 656 539 365 357 209 201 820 725 584 197 285 491 350 949 824 811 751 578 469 284 267 172 618 516 510 358 346 321 291 262 254 202 976 922 381 376 713 678 654 236 379 240 627 384 1053 948 731 663 643 405 188 647 569 556 555 508 496 453 302 189 167 881 806 745 632 565 436 303 233 161 772 727 696 597 573 983 959 848 793 575 269 268 211 718 571 733 833 812 257 218 541 944 899 861 777 392 251 235 634 374 297 891 877 834 810 754 525 253 682 410 343 259 752 889 776 186 366 938 931 928 921 798 275 222 230 1017 854 807 794 760 755 732 598 559 505 354 327 278 241 184 108 716 927 920 765 735 1242 885 893 875 780 679 652 562 308 274 157 771 763 939 901 827 758 239 664 383 897 206 1015 935 909 497 237 951 950 937 900 832 802 753 624 154 831 588 706 1018 979 968 842 542 923 589 513 468 378 330 325 293 288 217 335 287 263 177 171 917 916 404 220 997 870 610 591 1010 943 914 884 746 294 858 846 481 227 1002 797 790 234 668 978 836 792 781 873 825 279 423 391 1072 1064 1050 965 851 213 531 395 118 895 822 819 567 176 144 892 400 971 957 372 1131 1100 1039 714 546 514 183 942 905 843 823 874 461 482 307 141 669 629 519 322 828 907 465 332 1080 992 133 314 196 331 334 973 1068 1122 974 918 1250 1046 1025 857 890 947 817 1033 946 930 962 981 775 1092 1006 967 932 1079 1024 1016 955 283 229 1091 1065 1040 941 316 651 258 429 1044 57 1252 954 103 924 910 866 988 876 416 310 135 767 306 178 266 809 1038 1054 863 1007 693 328 769 837 830 1001 801 232 309 770 869 402 356 813 1049 305 373 853 789 786 906 336 473 523 155 246 417 975 1003 844 1005 782 1051 580 913 887 903 803 219 1034 238 413 1077 1099 1070 1090 1008 1112 292 1000 994 936 919 1144 933 1012 868 1106 1168 1028 1022 929 1163 1019 1067 969 1043 961 1030 1169 1084 277 894 1143 960 1103 1101 1212 1201 1035 273 915 1203 859 1063 1031 1075 1055 966 315 970 990 1119 1097 1056 1037 926 999 1094 1020 818 864 1111 1057 1185 1086 1156 170 1093 871 299 904 295 671 1071 1042 420 888 982 1009 1073 707 534 1188 1021 1216 1060 1052 998 1078 952 993 1313 1282 1076 1145 977 418 1243 1134 1214 985 872 1165 991 1110 1159 1226 1276 1029 1162 428 1184 958 1105 1196 1297 1013 1232 1220 1141 1286 1014 1085 1360 1062 1124 1231 1256 1058 1170 1142 1047 319 1098 1234 1116 1136 1027 1350 1115 1011 51 1200 53 46 250 1137 1081 934 1129 1189 1140 989 1096 1263 105 1066 382 783 249 1154 1036 1164 1113 260 1190 1280 1328 1320 298 1087 1130 1270 1183 1385 203 1209 148 980 1351 1182 1199 1167 1261 1259 1032 1155 1026 1227 1322 1023 1210 396 1284 1125 1095 1193 1118 270 1290 1354 311 1148 1380 1158 1151 1082 1215 1222 1177 1357 987 1128 1306 1126 1251 1074 272 1123 1133 1048 1340 282 326 1240 1211 1246 1223 1192 945 1139 1153 1337 286 1374 494 1194 1147 1127 964 1041 1204 1205 1135 300 1121 1272 1172 1260 1217 1174 1239 1061 1278 1339 1291 1344 1327 304 1157 1236 1069 313 1059 1338 1315 1317 1138 1412 1264 1271 375 1045 1166 1224 1237 1283 1173 175 1219 1274 1176 1191 1305 1089 1104 1249 162 1120 1267 1225 1178 281 1146 1202 1175 1186 1213 422 1195 1303 1171 1257 1235 1221 1245 1102 1266 1399 165 1160 1149 1132 1254 1230 1152 1248 1273 329 1258 1179 1295 1208 1268 1187 1294 1288 1206 290 1150 149 339 1181 194 1325 1255 1359 1464 1285 1292 1289 1238 1281 1389 185 1228 1423 1314 1218 1361 1253 1233 1180 1318 1323 1287 301 1275 1269 1298 1302 1348 1265 1373 1316 1371 1198 1353 1413 1363 1310 1456 150 1376 256 1332 134 27 123 1262 137 1324 1244 1247 247 1304 317 1241 1321 1301 1379 179 255 411 1375 1384 1447 1330 1367 341 399 164 208 1358 1207 1311 1277 289 125 296 1345 121 1341 231 117 1364 1319 191 1366 163 1293 1329 1396 1300 107 1342 1309 1326 1395 1334 1333 1343 1393 199 1369 147 139 124 110 116 39 23 31 192 120 109 131 112 111 127 104 173 166 129 115 146 138 169 54 130 122 119 126 58 56 158 159 35 221         Options:                          Outliers highlighted in  yellow  can be hidden using the Hide Outliers button,   and samples with no value (x) can be hidden by clicking Hide No Value . Index Sample Value Tissue Sex Age 1 GSM300166       2 GSM300167 SG F 91 3 GSM300168       4 GSM300169       5 GSM300170       6 GSM300171       7 GSM300172       8 GSM300173       9 GSM300174       10 GSM300175       11 GSM300176 SG M 45 12 GSM300177       13 GSM300178       14 GSM300179       15 GSM300180 SG M 95 16 GSM300181       17 GSM300182       18 GSM300183       19 GSM300185       20 GSM300186       21 GSM300187       22 GSM300188 SG F 45 23 GSM300189       24 GSM300190       25 GSM300191 SG F 74 26 GSM300192       27 GSM300193       28 GSM300194       29 GSM300195 SG F 99 30 GSM300196       31 GSM300197       32 GSM300198       33 GSM300199 SG F 74 34 GSM300200       35 GSM300201 SG F 92 36 GSM300202       37 GSM300203 SG F 91 38 GSM300204       39 GSM300205       40 GSM300206       41 GSM300207 SG M 83 42 GSM300208       43 GSM300209       44 GSM300210       45 GSM300211 SG M 28 46 GSM300212       47 GSM300213 SG F 74 48 GSM300214       49 GSM300215       50 GSM300216       51 GSM300217 SG M 97 52 GSM300218       53 GSM300219       54 GSM300220       55 GSM300221 SG F 34 56 GSM300222       57 GSM300223       58 GSM300224       59 GSM300225 SG F 74 60 GSM300226       61 GSM300227       62 GSM300228       63 GSM300229 SG F 44 64 GSM300230       65 GSM300231       66 GSM300232       67 GSM300233 SG F 37 68 GSM300234       69 GSM300235       70 GSM300236       71 GSM300237 SG M 85 72 GSM300238       73 GSM300239       74 GSM300240       75 GSM300241 SG F 70 76 GSM300242       77 GSM300243       78 GSM300244       79 GSM300245 SG F 64 80 GSM300246       81 GSM300247 SG M 70 82 GSM300248       83 GSM300249       84 GSM300250 SG F 85 85 GSM300251 SG F 91 86 GSM300252       87 GSM300253       88 GSM300254 SG M 21 89 GSM300255       90 GSM300256       91 GSM300258       92 GSM300259       93 GSM300260 SG M 40 94 GSM300261       95 GSM300262       96 GSM300263       97 GSM300264 SG M 80 98 GSM300265       99 GSM300266 SG M 52 100 GSM300267       101 GSM300268       102 GSM300269       103 GSM300270 SG M 75 104 GSM300271       105 GSM300272       106 GSM300273       107 GSM300274 SG M 86 108 GSM300275       109 GSM300276       110 GSM300277       111 GSM300278 SG F 26 112 GSM300279       113 GSM300280       114 GSM300281       115 GSM300282 SG M 20 116 GSM300283       117 GSM300284 SG M 20 118 GSM300285       119 GSM300286       120 GSM300287       121 GSM300288 SG F 36 122 GSM300289       123 GSM300290       124 GSM300291       125 GSM300292 SG M 69 126 GSM300293       127 GSM300294       128 GSM300295       129 GSM300296 SG F 44 130 GSM300297       131 GSM300298       132 GSM300299 SG F 48 133 GSM300300       134 GSM300301       135 GSM300302       136 GSM300303 SG F 30 137 GSM300304       138 GSM300305       139 GSM300306       140 GSM300307 SG M 20 141 GSM300308       142 GSM300309       143 GSM300310       144 GSM300311 SG M 33 145 GSM300312       146 GSM300313       147 GSM300314       148 GSM300315 SG M 22 149 GSM300316       150 GSM300317       151 GSM300318       152 GSM300319 SG M 42 153 GSM300320       154 GSM300321       155 GSM300322       156 GSM300323 SG M 45 157 GSM300324       158 GSM300325       159 GSM300326       160 GSM300327 SG F 47 161 GSM300328       162 GSM300329       163 GSM300330       164 GSM300331 SG M 69 165 GSM300332       166 GSM300333       167 GSM300335 SG F 91 168 GSM300338       169 GSM300339       170 GSM300340       171 GSM300341 SG M 75 172 GSM318840 SG F 82