Details and Links

Gene Symbol:		Chrna3
Description:		cholinergic receptor, nicotinic, alpha polypeptide 3
Location:		Chr 9 @ 55.012656 Mb on the minus strand
Target Score:
Species and Group:		Mouse, BHF2
Database 3:		UCLA BHF2 Liver Female mlratio
Resource Links:		Gene  OMIM  UniGene  GenBank  HomoloGene
		BioGPS  STRING  PANTHER  Gemma  ABA  EBI GWAS  Wiki-Pi

Add	Find	Verify	GeneWiki	SNPs

  Basic Statistics

Include: All Cases BHF2 Only Non-BHF2 Only    

Basic Table Probability Plot Bar Graph (by name) Bar Graph (by rank) Box Plot Statistic Value N of Samples 149 Mean -0.018 Median -0.015 Standard Error (SE) 0.004 Standard Deviation (SD) 0.052 Minimum -0.257 Maximum 0.258 This plot evaluates whether data are normally distributed. Different symbols represent different groups. More about Normal Probability Plots and more about interpreting these plots from the glossary More about Box Plots Basic Table Probability Plot Bar Graph (by name) Bar Graph (by rank) Box Plot Statistic Value N of Samples 148 Mean -0.018 Median -0.016 Standard Error (SE) 0.004 Standard Deviation (SD) 0.052 Minimum -0.257 Maximum 0.258 This plot evaluates whether data are normally distributed. Different symbols represent different groups. More about Normal Probability Plots and more about interpreting these plots from the glossary More about Box Plots Fewer than 4 non-BHF2 case data were entered. No statistical analysis has been attempted.

  Calculate Correlations

Sample r Literature r Tissue r Database: BHF2 Phenotypes BHF2 ApoE Null Genotype UCLA BHF2 Adipose Female mlratio UCLA BHF2 Adipose Male mlratio UCLA BHF2 Adipose (June05) mlratio UCLA BHF2 Brain Male mlratio UCLA BHF2 Brain Female mlratio UCLA BHF2 Brain (June05) mlratio UCLA BHF2 Liver Male mlratio UCLA BHF2 Liver Female mlratio UCLA BHF2 Liver (June05) mlratio UCLA BHF2 Muscle Male mlratio* UCLA BHF2 Muscle Female mlratio* UCLA BHF2 Muscle (June05) mlratio* Return: top 25 top 50 top 100 top 200 top 500 top 1000 top 2000 top 5000 top 10000 top 15000 top 20000 top 30000 top 40000 top 60000 Samples: BHF2 Only Non-BHF2 Only All Cases Pearson    Spearman Rank The Sample Correlation is computed between trait data and any other traits in the sample database selected above. Use Spearman Rank when the sample size is small (<20) or when there are influential outliers. Database: BHF2 Phenotypes BHF2 ApoE Null Genotype UCLA BHF2 Adipose Female mlratio UCLA BHF2 Adipose Male mlratio UCLA BHF2 Adipose (June05) mlratio UCLA BHF2 Brain Male mlratio UCLA BHF2 Brain Female mlratio UCLA BHF2 Brain (June05) mlratio UCLA BHF2 Liver Male mlratio UCLA BHF2 Liver Female mlratio UCLA BHF2 Liver (June05) mlratio UCLA BHF2 Muscle Male mlratio* UCLA BHF2 Muscle Female mlratio* UCLA BHF2 Muscle (June05) mlratio* Return: top 25 top 50 top 100 top 200 top 500 top 1000 top 2000 top 5000 top 10000 top 15000 top 20000 top 30000 top 40000 top 60000 Samples: BHF2 Only Non-BHF2 Only All Cases The Literature Correlation (Lit r) between this gene and all other genes is computed using the Semantic Gene Organizer and human, rat, and mouse data from PubMed. Values are ranked by Lit r, but Sample r and Tissue r are also displayed. More on using Lit r Database: BHF2 Phenotypes BHF2 ApoE Null Genotype UCLA BHF2 Adipose Female mlratio UCLA BHF2 Adipose Male mlratio UCLA BHF2 Adipose (June05) mlratio UCLA BHF2 Brain Male mlratio UCLA BHF2 Brain Female mlratio UCLA BHF2 Brain (June05) mlratio UCLA BHF2 Liver Male mlratio UCLA BHF2 Liver Female mlratio UCLA BHF2 Liver (June05) mlratio UCLA BHF2 Muscle Male mlratio* UCLA BHF2 Muscle Female mlratio* UCLA BHF2 Muscle (June05) mlratio* Return: top 25 top 50 top 100 top 200 top 500 top 1000 top 2000 top 5000 top 10000 top 15000 top 20000 top 30000 top 40000 top 60000 Samples: BHF2 Only Non-BHF2 Only All Cases Pearson    Spearman Rank The Tissue Correlation (Tissue r) estimates the similarity of expression of two genes or transcripts across different cells, tissues, or organs (glossary). Tissue correlations are generated by analyzing expression in multiple samples usually taken from single cases. Pearson and Spearman Rank correlations have been computed for all pairs of genes using data from mouse samples.

  Mapping Tools

Interval Marker Regression Composite Pair-Scan Chromosome: All 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Mapping Scale: Megabase Centimorgan Permutations: Bootstrap Test (n=2000) Use Parents Use Weighted Interval Mapping computes linkage maps for the entire genome or single chromosomes. The Permutation Test estimates suggestive and significant linkage scores. The Bootstrap Test estimates the precision of the QTL location. Display LRS above: Permutations: Display all LRS Use Parents Use Weighted Marker regression computes and displays LRS values for individual markers. This function also lists additive effects (phenotype units per allele) and dominance deviations for some datasets. Chromosome: All 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Mapping Scale: Megabase Centimorgan Control Locus: Permutations: Bootstrap Test (n=2000) Use Parents Composite Interval Mapping allows you to control for a single marker as a cofactor. To find a control marker, run the Marker Regression function. Sort by: LRS Full LRS Interact Return: top 50 top 100 top 200 top 500 Permutation Test (n=500) Pair-Scan searches for pairs of chromosomal regions that are involved in two-locus epistatic interactions.

  Review and Edit Data

Edit or delete values in the Trait Data boxes, and use the Reset option as needed.   Block samples by index:         BHF2 Only Non-BHF2 Only       Block samples by group:      Status Rrid Epoch Seqcvge       None Live UTHSC Cryo Ext Cyro Normal Alzheimer's N AD CIE AIR None JAX:100006 JAX:000664 JAX:000671 JAX:000036 JAX:000075 JAX:000037 JAX:000007 JAX:000084 JAX:000105 JAX:000012 JAX:000045 JAX:000040 JAX:000329 JAX:000095 JAX:000013 JAX:000015 JAX:000010 JAX:000330 JAX:000077 JAX:000043 JAX:000098 JAX:000031 JAX:000081 JAX:000041 JAX:000047 JAX:010981 JAX:000073 JAX:000083 JAX:000078 JAX:003222 JAX:032926 JAX:003225 JAX:003227 JAX:003228 JAX:003229 JAX:003230 JAX:007112 JAX:007113 JAX:007093 JAX:007094 JAX:007096 JAX:007097 JAX:007098 JAX:007099 JAX:007100 JAX:017749 JAX:007103 JAX:007104 JAX:007105 JAX:007106 JAX:007107 JAX:007108 JAX:007109 JAX:007110 JAX:007111 JAX:007114 JAX:007115 JAX:007116 JAX:007117 JAX:007118 JAX:007119 JAX:007121 JAX:024029 JAX:007123 JAX:007124 JAX:007125 JAX:007126 JAX:007127 JAX:007128 JAX:007129 JAX:007130 JAX:017750 JAX:007132 JAX:007133 JAX:017751 JAX:009677 JAX:007139 JAX:007140 JAX:007141 JAX:007138 JAX:007142 JAX:007143 JAX:007144 JAX:007145 JAX:007146 JAX:030873 JAX:025975 JAX:024030 JAX:025974 JAX:024031 JAX:030874 JAX:030875 JAX:035596 JAX:035597 JAX:025984 JAX:035598 JAX:029867 JAX:029868 JAX:029869 JAX:025976 JAX:029870 JAX:029871 JAX:029872 JAX:029873 JAX:025985 JAX:035599 JAX:029874 JAX:029876 JAX:029878 JAX:029879 JAX:029880 JAX:035600 JAX:035601 JAX:029881 JAX:029882 JAX:029883 JAX:035602 JAX:031974 JAX:030876 JAX:030877 JAX:030878 JAX:030880 JAX:030881 JAX:031975 JAX:035603 JAX:030882 JAX:031977 JAX:031978 JAX:035604 RGD_631848 RGD_61117 RGD_2307094 RGD_2307096 RGD_2307079 RGD_2307077 RGD_2307099 RGD_2307086 RGD_2307083 RGD_2307091 RGD_2307092 RGD_2307095 RGD_2307085 RGD_2307082 RGD_2307080 RGD_2307097 RGD_2307088 RGD_2307093 RGD_2307084 RGD_2307098 RGD_2307078 RGD_2307089 RGD_2307081 RGD_2307121 RGD_2307134 RGD_2307115 RGD_2307136 RGD_2307126 RGD_2307129 RGD_2307124 RGD_2307127 RGD_2307139 RGD_2307123 RGD_629485 RGD_1302686 RGD_1302641 RGD_1302666 RGD_1302605 RGD_1302710 RGD_1302646 RGD_1302707 RGD_1302604 RGD_1302723 RGD_1302617 RGD_1302652 RGD_1302649 RGD_1302597 RGD_1302653 RGD_1302699 RGD_1302618 RGD_1302621 RGD_1302616 RGD_1302612 RGD_1302638 RGD_1302602 RGD_1302665 RGD_1302615 RGD_1302673 RGD_1302619 RGD_1302708 RGD_1302682 RGD_1302690 RGD_1302633 RGD_1302607 RGD_1302683 RGD_1302601 RGD_1302611 RGD_1302603 RGD_1302598 RGD_10000 RGD_737892 RGD_10401918 RGD_2304285 RGD_1566456 RGD_2307298 RGD_61498 RGD_5508393 RGD_1578713 RGD_2311070 RGD_61118 RGD_60986 RGD_2307359 RGD_1358153 RGD_734475 RGD_734478 RGD_737926 RGD_61109 RGD_1302627 RGD_737893 RGD_629509 RGD_1579686 RGD_10395297 RGD_1566455 RGD_1302600 RGD_631163 RGD_737932 RGD_737922 RGD_60990 RGD_68077 RGD_61015 RGD_10023 RGD_9999143 RGD_2307358 RGD_10024 RGD_2307319 RGD_10028 RGD_70449 RGD_737906 RGD_6482298 RGD_634381 RGD_634380 RGD_728161 RGD_629486 RGD_1302722 RGD_1302660 RGD_1358258 RGD_631572 RGD_631573 RGD_1357994 RGD_2311051 RGD_1581618 RGD_1559047 RGD_734759 RGD_631599 RGD_1559041 RGD_1582184 RGD_61499 RGD_2312498 RGD_1358112 RGD_61105 RGD_10045 JAX:003223 JAX:0030872 JAX:000GET JAX:029885 JAX:030879 x JAX:0029873 JAX:029865 JAX:029866 JAX:029884 None 0 1 2 3b 3a 4 5 6 1b 1c None 69 108 36+39L 40 32 37 38 42 43 39 35 36 41 40+54L 30 40+35L 34 33 41+61L 29 36+30L 44 41+43L 38+55L 40+31L 45 31 39+37L 46 27 69.14 107.80 36.03 40.44 32.01 36.63 38.14 42.34 42.48 39.91 38.92 37.36 35.24 36.00 43.21 41.28 36.89 35.51 38.69 35.03 40.15 40.03 38.25 38.90 40.19 40.88 30.27 39.97 38.17 39.54 38.66 33.75 38.19 40.47 41.10 39.65 40.37 42.32 39.94 41.19 37.61 41.04 39.08 39.25 37.21 33.40 39.15 36.51 38.88 38.70 41.12 33.43 35.86 34.42 39.44 40.41 36.47 33.74 37.79 41.48 41.39 41.77 39.90 41.79 32.16 37.73 38.71 40.05 28.89 38.41 36.79 36.92 40.53 42.80 41.00 40.24 40.55 35.97 39.20 38.85 41.34 40.23 37.76 38.63 39.62 37.32 33.73 39.53 36.28 35.76 42.39 39.51 38.12 40.49 38.02 37.43 40.93 39.43 30.61 38.95 37.95 40.18 39.07 44.48 31.66 42.83 28.48 36.25 43.74 39.00 39.95 32.73 38.37 40.27         Options:                          Outliers highlighted in  yellow  can be hidden using the Hide Outliers button,   and samples with no value (x) can be hidden by clicking Hide No Value . Index Sample Value Status RRID Epoch SeqCvge 5 BHF2001 6 BHF2002 7 BHF2003 8 BHF2004 9 BHF2005 10 BHF2006 11 BHF2007 12 BHF2008 13 BHF2009 14 BHF2010 15 BHF2011 16 BHF2013 17 BHF2014 18 BHF2015 19 BHF2016 20 BHF2017 21 BHF2018 22 BHF2019 23 BHF2020 24 BHF2021 25 BHF2022 26 BHF2023 27 BHF2024 28 BHF2026 29 BHF2027 30 BHF2028 31 BHF2029 32 BHF2030 33 BHF2031 34 BHF2032 35 BHF2033 36 BHF2034 37 BHF2035 38 BHF2036 39 BHF2037 40 BHF2038 41 BHF2039 42 BHF2040 43 BHF2041 44 BHF2042 45 BHF2043 46 BHF2044 47 BHF2045 48 BHF2046 49 BHF2047 50 BHF2048 51 BHF2049 52 BHF2050 53 BHF2051 54 BHF2052 55 BHF2054 56 BHF2055 57 BHF2056 58 BHF2057 59 BHF2059 60 BHF2060 61 BHF2061 62 BHF2062 63 BHF2063 64 BHF2064 65 BHF2065 66 BHF2066 67 BHF2067 68 BHF2068 69 BHF2069 70 BHF2070 71 BHF2071 72 BHF2072 73 BHF2073 74 BHF2074 75 BHF2075 76 BHF2076 77 BHF2077 78 BHF2078 79 BHF2079 80 BHF2080 81 BHF2081 82 BHF2082 83 BHF2083 84 BHF2084 85 BHF2085 86 BHF2086 87 BHF2087 88 BHF2088 89 BHF2089 90 BHF2091 91 BHF2092 92 BHF2093 93 BHF2094 94 BHF2103 95 BHF2104 96 BHF2105 97 BHF2107 98 BHF2108 99 BHF2109 100 BHF2110 101 BHF2111 102 BHF2112 103 BHF2113 104 BHF2114 105 BHF2116 106 BHF2117 107 BHF2118 108 BHF2119 109 BHF2120 110 BHF2121 111 BHF2122 112 BHF2123 113 BHF2124 114 BHF2125 115 BHF2126 116 BHF2127 117 BHF2140 118 BHF2142 119 BHF2143 120 BHF2144 121 BHF2145 122 BHF2146 123 BHF2147 124 BHF2148 125 BHF2149 126 BHF2150 127 BHF2151 128 BHF2152 129 BHF2153 130 BHF2154 131 BHF2155 132 BHF2156 133 BHF2157 134 BHF2158 135 BHF2159 136 BHF2160 137 BHF2161 138 BHF2162 139 BHF2163 140 BHF2164 141 BHF2165 142 BHF2166 143 BHF2167 144 BHF2169 145 BHF2170 146 BHF2171 147 BHF2172 148 BHF2173 149 BHF2174 150 BHF2175 151 BHF2176 152 BHF2177 153 BHF2178 154 BHF2179 155 BHF2180 156 BHF2181 157 BHF2182 158 BHF2183 159 BHF2184 160 BHF2185 161 BHF2186 162 BHF2187 163 BHF2188 164 BHF2189 165 BHF2190 166 BHF2191 167 BHF2192 168 BHF2193 169 BHF2194 170 BHF2195 171 BHF2196 172 BHF2197 173 BHF2198 174 BHF2199 175 BHF2200 176 BHF2201 177 BHF2202 178 BHF2207 179 BHF2208 180 BHF2209 181 BHF2210 182 BHF2211 183 BHF2212 184 BHF2213 185 BHF2214 186 BHF2215 187 BHF2216 188 BHF2217 189 BHF2218 190 BHF2219 191 BHF2220 192 BHF2221 193 BHF2222 194 BHF2223 195 BHF2224 196 BHF2225 197 BHF2226 198 BHF2227 199 BHF2228 200 BHF2230 201 BHF2231 202 BHF2232 203 BHF2233 204 BHF2234 205 BHF2235 206 BHF2236 207 BHF2237 208 BHF2238 209 BHF2239 210 BHF2241 211 BHF2242 212 BHF2243 213 BHF2244 214 BHF2245 215 BHF2246 216 BHF2247 217 BHF2248 218 BHF2249 219 BHF2250 220 BHF2251 221 BHF2252 222 BHF2253 223 BHF2254 224 BHF2255 225 BHF2256 226 BHF2257 227 BHF2258 228 BHF2260 229 BHF2261 230 BHF2262 231 BHF2263 232 BHF2264 233 BHF2265 234 BHF2266 235 BHF2267 236 BHF2268 237 BHF2269 238 BHF2270 239 BHF2271 240 BHF2272 241 BHF2273 242 BHF2274 243 BHF2275 244 BHF2276 245 BHF2278 246 BHF2279 247 BHF2280 248 BHF2281 249 BHF2282 250 BHF2283 251 BHF2284 252 BHF2285 253 BHF2286 254 BHF2287 255 BHF2288 256 BHF2289 257 BHF2290 258 BHF2291 259 BHF2292 260 BHF2293 261 BHF2294 262 BHF2295 263 BHF2296 264 BHF2297 265 BHF2298 266 BHF2299 267 BHF2300 268 BHF2301 269 BHF2302 270 BHF2303 271 BHF2304 272 BHF2305 273 BHF2306 274 BHF2307 275 BHF2308 276 BHF2309 277 BHF2310 278 BHF2311 279 BHF2312 280 BHF2313 281 BHF2314 282 BHF2315 283 BHF2316 284 BHF2317 285 BHF2318 286 BHF2319 287 BHF2320 288 BHF2321 289 BHF2322 290 BHF2323 291 BHF2324 292 BHF2325 293 BHF2326 294 BHF2327 295 BHF2328 296 BHF2329 297 BHF2330 298 BHF2331 299 BHF2332 300 BHF2333 301 BHF2334 302 BHF2335 303 BHF2336 304 BHF2337 305 BHF2338 306 BHF2339 307 BHF2340 308 BHF2341 309 BHF2342 310 BHF2343 311 BHF2344 312 BHF2345 313 BHF2346 314 BHF2347 315 BHF2348 316 BHF2349 317 BHF2350 318 BHF2351 319 BHF2352 320 BHF2353 321 BHF2354 322 BHF2355 323 BHF2356 324 BHF2357 325 BHF2358   Index Sample Value Status RRID Epoch SeqCvge 5 BHF2359