Data Set Group: UCLA BHF2 Brain mlratio
| Data Set: UCLA BHF2 Brain (June05) mlratio |
| GN Accession: GN166 |
| GEO Series: GSE3087 |
| Title: Expression profiling of brain tissue from (C57BL/6J X C3H/HeJ)F2 mice on ApoE null backgrounds |
| Organism: Mouse (Mus musculus, mm10) |
| Group: BHF2 |
| Tissue: Brain mRNA |
| Dataset Status: Public |
| Platforms: Agilent Mouse Custom (GPL2510) |
| Normalization: mlratio |
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| Contact Information |
Aldons Lusis
University of California, Los Angeles
UCLA Med-Cardio/Microbio BOX 951679
Los Angeles, CA 90095 USA
Tel. 310 825-1359
jlusis@mednet.ucla.edu
Website
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| Download datasets and supplementary data files |
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| Specifics of this Data Set: |
None
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| Summary: |
| The (C57BL/6J X C3H/HeJ)F2 intercross consists of 334 animals of both sexes. All are ApoE null and received a high fat Western diet from 8-24 weeks of age.
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| About the cases used to generate this set of data: |
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| About the tissue used to generate this set of data: |
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| About the array platform: |
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| About data values and data processing: |
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| Notes: |
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| Experiment Type: |
| Brain from 249 F2 female and male mice (animals fed a high fat "Western" diet from 8-24 weeks of age.) derived from C57BL/6J and C3H/HeJ parental strains with both on ApoE null backgrounds. All samples were compared to a common pool created from equal portions of RNA from each of the samples. Keywords=Genetics of Gene Expression Keywords=C57BL/6J Keywords=C3H/HeJ
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| Contributor: |
| Yang X, Schadt EE, Wang S, Wang H, Arnold AP, Ingram-Drake L, Drake TA, Lusis AJ
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| Citation: |
- Yang X, Schadt EE, Wang S, Wang H et al. Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res 2006 Aug;16(8):995-1004. PMID: 16825664
- van Nas A, Ingram-Drake L, Sinsheimer JS, Wang SS et al. Expression quantitative trait loci: replication, tissue- and sex-specificity in mice. Genetics2010 Jul;185(3):1059-68. PMID: 20439777
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| Data source acknowledgment: |
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| Study Id: |
48
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GeneNetwork support from:
- The UT Center for Integrative and Translational Genomics
- NIGMS Systems Genetics and Precision Medicine project (R01 GM123489, 2017-2021)
- NIDA NIDA Core Center of Excellence in Transcriptomics, Systems Genetics,
and the Addictome (P30 DA044223, 2017-2022)
- NIA Translational Systems Genetics of Mitochondria, Metabolism, and Aging (R01AG043930, 2013-2018)
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