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Data Set Group2: GSE16780 UCLA Hybrid MDP Liver Affy HT M430A (Sep11)
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Contact Information |
Aldons Lusis
University of California, Los Angeles
UCLA Med-Cardio/Microbio BOX 951679
Los Angeles, CA 90095 USA
Tel. 310 825-1359
jlusis@mednet.ucla.edu
Website
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Download datasets and supplementary data files |
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Specifics of this Data Set: |
None
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Summary: |
Novel, systems-based approach to mouse genetics.
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About the cases used to generate this set of data: |
For complete information please refer to Bennett BJ, Farber CR, Orozco L, Kang HM, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, Kirchgessner T, Pan C, Castellani LW, Kostem E, Furlotte N, Drake TA, Eskin E, Lusis AJ (2010) A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Research 20:281-90 PMID: 20054062
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About the tissue used to generate this set of data: |
Hybrid Mouse diversity Panel Liver Expression Profile
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About the array platform: |
Platform GPL8759 [HT_MG-430A] Affymetrix HT Mouse Genome 430A Array
The probe sets were selected from sequences derived from GenBank®, dbEST and RefSeq. The sequence clusters were created from the UniGene database (Build 107, June 2002) and then refined by analysis and comparison with the publicly available draft assembly of the mouse genome from the Whitehead Institute Center for Genome Research (MSCG, April 2002).
Oligonucleotide probes complementary to each corresponding sequence are synthesized in situ on the array. Eleven pairs of oligonucleotide probes, including a perfect match and mismatch probe, are used to measure the level of transcription of each sequence represented on the GeneChip® HT Mouse Genome 430 Array Plate Set.
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About data values and data processing: |
For complete information please refer to A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res 2010 Feb;20(2):281-90. PMID: 20054062
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Notes: |
Raw data provided as supplementary file at GEO Series GSE16780
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Experiment Type: |
Expression profiling by array.
Expression Profiles from 99 strains of inbred and recombinant inbred mice. Most assayed in triplicate. Two of 288 chips were excluded from the final analysis due to low QC scores.
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Contributor: |
Bennett BJ, Ghazalpour A
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Citation: |
Bennett BJ, Farber CR, Orozco L, Kang HM et al. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res 2010 Feb;20(2):281-90. PMID: 20054062
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Data source acknowledgment: |
Bennett BJ, Ghazalpour A
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Study Id: |
136
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GeneNetwork support from:
- The UT Center for Integrative and Translational Genomics
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and the Addictome (P30 DA044223, 2017-2022)
- NIA Translational Systems Genetics of Mitochondria, Metabolism, and Aging (R01AG043930, 2013-2018)
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