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Data Set Group2: JAX BXD Hippocampal Proteome (Feb19) modify this page

Data Set: JAX BXD Hippocampal Proteome (Feb19) modify this page
GN Accession: GN873
GEO Series: No GEO series yet
Organism: Mouse (Mus musculus, mm10)
Group: BXD-Longevity
Tissue: Hippocampus Proteome
Dataset Status: Public
Platforms: Custom Hippocampal Proteome
Normalization: Log2
Contact Information
Robert Williams
University of Tennessee Health Science Center
71 S Manassas St, Room 405 TSRB
Memphis, TN 38163 USA
Tel. 901 448-7050
Download datasets and supplementary data files

Specifics of this Data Set:
BXD Hippocampal Proteome


A total of 244 male and female mice (Female: n=214; Male: n=30) from 40 BXD recombinant inbred strains were used in this study (2-37.1 mo; 15.94 ± 5.6 mo) aimed to understand changes to the hippocampal proteome across lifespan in a genetically diverse mouse population. Mice were group housed (2–5 per cage) and maintained in colony housing (12-hour light/dark cycle) with ad libitum access to water and fed either standard laboratory diet or high-fat diet (n=125 standard diet; n=119 HFD).

Data files available at https://files.genenetwork.org/current/GN873/

About the cases used to generate this set of data:

About the tissue used to generate this set of data:

Whole hippocampus (single hemisphere)

About the array platform:

SWATH Mass Spectrometry on the TripleTOF

About data values and data processing:


Experiment Type:


Catherine Kaczorowski


Data source acknowledgment:

Study Id:

CITG Web services initiated January, 1994 as Portable Dictionary of the Mouse Genome; June 15, 2001 as WebQTL; and Jan 5, 2005 as GeneNetwork. This site is currently operated by Rob Williams, Pjotr Prins, Zachary Sloan, Arthur Centeno. Design and code by Pjotr Prins, Zach Sloan, Arthur Centeno, Danny Arends, Christian Fischer, Sam Ockman, Lei Yan, Xiaodong Zhou, Christian Fernandez, Ning Liu, Rudi Alberts, Elissa Chesler, Sujoy Roy, Evan G. Williams, Alexander G. Williams, Kenneth Manly, Jintao Wang, and Robert W. Williams, colleagues. Python Powered Registered with Nif
GeneNetwork support from:
  • The UT Center for Integrative and Translational Genomics
  • NIGMS Systems Genetics and Precision Medicine project (R01 GM123489, 2017-2021)
  • NIDA NIDA Core Center of Excellence in Transcriptomics, Systems Genetics, and the Addictome (P30 DA044223, 2017-2022)
  • NIA Translational Systems Genetics of Mitochondria, Metabolism, and Aging (R01AG043930, 2013-2018)
  • NIAAA Integrative Neuroscience Initiative on Alcoholism (U01 AA016662, U01 AA013499, U24 AA013513, U01 AA014425, 2006-2017)
  • NIDA, NIMH, and NIAAA (P20-DA 21131, 2001-2012)
  • NCI MMHCC (U01CA105417), NCRR, BIRN, (U24 RR021760)
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