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1.
nleA is involved in the ability of bacteria to transmit between hosts. (Mus musculus) PubMed
2.
Facilitation of bone marrow transplantation is dependent on facilitating cell (FC) expression of a unique heterodimer consisting of the T cell receptor beta-chain and a 33-kDa protein, FCp33. (FCp33) (Mus musculus) PubMed
3.
developmental expression of vitamin K-dependent gamma-carboxylase activity in zebrafish embryos and effect of warfarin [vitamin K-dependent carboxylase] (Mus musculus) PubMed
4.
Tbx5 and Wnt2b function together to initiate and specify forelimb outgrowth and identity.Tbx5 functions downstream of WNT signaling to regulate Fgf10, which, in turn, maintains Tbx5 expression during limb outgrowth [WNT-2B, FGF-10] (Mus musculus) PubMed
5.
mib interacts with the intracellular domain of Delta to promote its ubiquitylation and internalization; mib is essential for efficient activation of Notch signaling by Delta [mind bomb mib] (Mus musculus) PubMed
6.
zCRY and zPER2 regulate the sub-cellular distributions of zBMAL3 (BMAL3). (Mus musculus) PubMed
7.
molecular cloning, expression, and functional characterization of zebrafish SULT1 ST1 and SULT1 ST2 [SULT1 ST1/SULT1 ST2] (Mus musculus) PubMed
8.
Sema4E is repulsive for facial and gill motor axons and functions as a barrier for these axons within the pharyngeal arches. (sema4E) (Mus musculus) PubMed
9.
Results suggest that the reg6 mutation causes defects in branch formation and/or angiogenic sprouting [reg6]. (Mus musculus) PubMed
10.
the zebrafish prepro-ORX gene had one exon in contrast to mammals; The ORX-A peptide was less conserved than the ORX-B peptide compared with other vertebrates. Organization of the ORX system of zebrafish was similar to that of mammals [Prepro-orexin] (Mus musculus) PubMed
11.
The peak absorption spectrum (lambdamax) of the zebrafish blue visual pigment is consistently shifted to short wavelength compared with that of the goldfish (blue opsin) (Mus musculus) PubMed
12.
a novel family of parasitation-induced -RFamide neuropeptides that inhibit the activity of neuroendocrine cells in Lymnaea stagnalis. (Mus musculus) PubMed
13.
Zebrafish possess a rhodopsin-porphyropsin interchange system that functions to spectrally tune rod and cone photoreceptors. (Rhodopsin) (Mus musculus) PubMed
14.
role for the dazed gene in rod and Muller cell development and overall retinal cell survival and maintenance [dazed] (Mus musculus) PubMed
15.
nephrin-positive glomeral nexus does form anteriorly and links the two structures from stage 38 onward (Mus musculus) PubMed
16.
membrane-type 1 metalloproteinase (MT1-MMP), gelatinase A, and tissue inhibitor 2 of metalloproteinases mRNA transcripts were expressed in the blastema [MT1-MMP] (Mus musculus) PubMed
17.
This work supports the hypothesis that Homer is an important molecule in neuronal circuit development, necessary for crucial behaviors required for development and survival.(Homer 1c) (Mus musculus) PubMed
18.
The Proto-Oncogene Proteins b-myb is a ubiquitously expressed transcription factor involved in cellular proliferation and cancer. (Mus musculus) PubMed
19.
aryl acylamidase associated with acetylcholinesterase was higher than the esterase activity on zebrafishembryo [aryl acylamidase] (Mus musculus) PubMed
20.
The production of loss-of-function models for znfl2, znfl2b and znfl2/znfl2b together suggested that these erythrocyte specific zinc finger genes are dispensible for erythropoiesis. (finger-like gene 2b) (Mus musculus) PubMed
21.
Alpha1T-expressing Muller glia dedifferentiate and mediate regeneration of the injured zebrafish retina. (Alpha1 tubulin) (Mus musculus) PubMed
22.
Zebra fish foxl1 is a novel regulator of neural development that acts by suppressing shh expression. (Mus musculus) PubMed
23.
zCaMKP-N plays a crucial role in the early development of zebrafish.[zCaMKP-N] (Mus musculus) PubMed
24.
integrity of the N-terminal region and the first armadillo repeat are necessary and sufficient for high-affinity phosphorylation by CK1 of Ser-45[protein kinase CK1] (Mus musculus) PubMed
25.
Here we further demonstrated that zebrafish Mib and Mib2, similar to their mouse orthologs, have a C-terminal-most RING finger-dependent E3 ubiquitin ligase activity. Mib and Mib2 are reciprocal E3 ubiquitin ligases and substrates. (Mus musculus) PubMed
26.
propose a critical role for Baf60c in Notch-dependent transcription and left-right asymmetry[Baf60c] (Mus musculus) PubMed
27.
GST Pi plays role in the detoxification mechanism of freshwater fishes (Mus musculus) PubMed
28.
The expression of the four DrPcdh subclusters was analysed and DrPcdh transcripts are upregulated in the developing zebrafish nervous system. (Mus musculus) PubMed
29.
Danio rerio appears to be a suitable model to gain insight into the basic physiological functions of meprin metalloproteases[ meprin alpha2] (Mus musculus) PubMed
30.
Syntenin binding to Delta1 plays a dual role in promoting intercellular adhesion and regulating Notch signalling.[Delta1] (Mus musculus) PubMed
31.
Ectopic circumferential expression of chordin and other dorsal genes is completely dependent on Nodal and fibroblast growth factor signaling, and is independent of a functional organizer. (Nodal) (Mus musculus) PubMed
32.
The present study describes the isolation, sequencing and initial characterisation of an androgen receptor from zebrafish Danio rerio. (Mus musculus) PubMed
33.
These results demonstrate that zfTRPM5 and PLC-beta2 colocalize in zebrafish taste receptor cells--zftrpm5 (Mus musculus) PubMed
34.
Hsp90alpha1 plays an important role in muscle development, likely through facilitating myosin folding and assembly into organized myofibril filaments [Hsp90alpha1] (Mus musculus) PubMed
35.
Axon terminals contain bicuculline-sensitive GABAA receptors and both picrotoxin-sensitive and insensitive GABAC receptors. Dendritic processes express zinc- and picrotoxin-sensitive GABAC receptors. (GABA C receptor) (Mus musculus) PubMed
36.
The first X-ray crystal structures of zebrafish ribonucleases, RNases ZF-1a and-3e at 1.35-and 1.85 A resolution, respectively, is presented.[Rnase A] (Mus musculus) PubMed
37.
The function and structure of the zebrafish (Danio rerio) Na+-sulfate cotransporter 1 (NaS1) cDNA and gene (slc13a1), was characterized.[NaS1] (Mus musculus) PubMed
38.
Homozygous mno mutant embryos have a defect in the protoporphyrinogen oxidase gene. By 36 hours post-fertilization they are visibly anemic and porphyric. Human ppox partially rescues them. MNO. (Mus musculus) PubMed
39.
Two putative cytosolic sulfotransferase sequences from zebrafish, designated SULT3 ST1 and ST2, were identified.[ST1, ST2] (Mus musculus) PubMed
40.
Developmental expression analysis in zebrafish showed that K23 transcripts were maternally expressed in ovum and the amount of K23 transcripts increased gradually from zygote to pharyngula period [K23 protein] (Mus musculus) PubMed
41.
SIN3 is required for multiple developmental events during the Drosophila life cycle[SIN3a] (Mus musculus) PubMed
42.
Cdc2l1 is a previously unrecognized member of the Hh signal transduction cascade. (Mus musculus) PubMed
43.
identification/characterization of a novel exocrine cell determinant gene, exdpf, highly expressed in the exocrine cell progenitors and differentiated cells of the developing pancreas in zebrafish [exocrine differentiation and proliferation factor, exdpf] (Mus musculus) PubMed
44.
The data provide first evidence of the presence of Mel(1a) melatonin receptor in carp ovary and offer interesting perspectives especially for the study of the mechanisms of the control of its rhythmicity and its response to external factors. (Mus musculus) PubMed
45.
mgo mutation genetically interacts with pax2a required for the initiation of mid-hindbrain boundary formation[mgo] (Mus musculus) PubMed
46.
Activation of PKCgamma is necessary for the activity-dependent trafficking of AMPARs in embryonic zebrafish and is NMDA and SNARE-dependent and requires AMPARs to associate with both NSF and PICK1.[PICK1] (Mus musculus) PubMed
47.
Results demonstrate that the vascular-specific marker angiomodulin (AGM) modulates vascular remodeling in part by temporizing the proangiogenic effects of VEGF-A. (Mus musculus) PubMed
48.
Knockdown analysis using antisense morpholinos shows that reducing Axud1 levels impairs neural progenitor cell proliferation and survival, revealing an essential function of this gene for the growth of cephalic derivatives. (Axud1/Csrnp1) (Mus musculus) PubMed
49.
LC8 facilitates nuclear import of Pak1 and this function is indispensable during vertebrate development [DYNLL1] (Mus musculus) PubMed
50.
This study investigated the expression of genes encoding enzymes involved in long-chain polyunsaturated fatty acid biosynthesis, namely fatty acyl desaturase and Elovl5- and Elovl2-like elongases, during early embryonic development of zebrafish.[Fad] (Mus musculus) PubMed
51.
Targeted knockdowns of all five genes of heme biosynthesis resulted in profound anemia without impacting erythroid lineage specification. (Mus musculus) PubMed
52.
zebrafish lissencephaly 1 plays a very important role in embryonic development[lissencephaly 1a and lissencephaly 1b] (Mus musculus) PubMed
53.
Data show that microtubules in neighboring cells reorient and target p115 RhoGEF to sites where dying cells are squeezed out of the epithelial sheet [p115 RhoGEF]. (Mus musculus) PubMed
54.
Mg2+ regulates the cardiac mitoKATP channel from the matrix site by affecting both the channel conductance and gating. (Mus musculus) PubMed
55.
FMSF showed high protein specificity and affinity for activating forward motility of goat cauda epididymal spermatozoa.[FMSF] (Mus musculus) PubMed
56.
in endothelial cells CAMKII exerts a profound inhibition of endoplasmic reticulum Ca(2+) release, which is mediated by glycolytically generated ATP, possibly through ATP-dependent phosphorylation of the IP(3)R. (Mus musculus) PubMed
57.
TOR deficiency results in developmental arrest at mid-to-late L3, which is accompanied by marked gonadal degeneration and a pronounced intestinal cell phenotype. TOR is a major upstream regulator of overall mRNA translation in C. elegans [TOR] (Mus musculus) PubMed
58.
Crystals diffracted to 1.75 A and belong to the orthorhombic space group P2(1)2(1)2(1), with unit-cell parameters a = 44.3, b = 54.3, c = 60.2 A [ubiquitin-conjugation enzyme M7.1] (Mus musculus) PubMed
59.
the genomic structure of PRKCD was analyzed; exon-intron genomic structure is highly conserved among mammals, while significantly diverged in C. elegans [PKC-delta] (Mus musculus) PubMed
60.
AF9, called GLGPRPLRF-NH2 (AF9), is a ligand activating the cloned NPR-1 receptor [AF9] (Mus musculus) PubMed
61.
expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1 is coordinated [two entries: Fre-1 and DCS-1] (Mus musculus) PubMed
62.
Tudor-SN (tudor staphylococcal nuclease)--a protein containing five staphylococcal/micrococcal nuclease domains and a tudor domain--is a component of the RISC enzyme in Caenorhabditis elegans, Drosophila and mammals [Tudor-SN] (Mus musculus) PubMed
63.
study of critical residues of choline kinase A2 [CKA-2] (Mus musculus) PubMed
64.
Nuclear membrane protein that colocalizes with Ce-lamin and binds Ce-lamin but does not require Ce-lamin for its localization. (Matefin, mtf-1) (Mus musculus) PubMed
65.
OSR-1 plays a central role in integrating stress detection and adaptation responses by invoking multiple signaling pathways to promote survival under hyperosmotic environments [OSR1] (Mus musculus) PubMed
66.
Loss of function of this gene leads to the activation of a ced-3-dependent, ced-4-independent form of programmed cell death (pvl-5 gene) (Mus musculus) PubMed
67.
cloning and the characterization of the third FMRFamide-related peptide (FaRP) receptor in Caenorhabditis elegans, the VRFa receptor 1 [VRfa receptor 1] (Mus musculus) PubMed
srf-3 is a mutant of Caenorhabditis elegans deficient in glycoconjugates (Mus musculus) PubMed
70.
SPD-1 is a conserved microtubule-bundling protein that localizes to the spindle midzone and may play an early role in the pathway of midzone assembly. (Mus musculus) PubMed
71.
hyperactivation of the Caenorhabditis elegans FGF receptor, EGL-15, similarly inhibits the differentiation of the hermaphrodite sex muscles (Mus musculus) PubMed
72.
chondroitin polymerizing factor shows cell and organ-specific expression and has a critical role in chondroitin synthesis and embryonic cell division (Mus musculus) PubMed
73.
results support the hypothesis that ncr-1 and ncr-2 are involved in intracellular cholesterol processing in C. elegans, and that a sterol-signaling defect is responsible for the Daf-c phenotype of the ncr-2; ncr-1 mutant [ncr1, ncr2] (Mus musculus) PubMed
74.
AMP-activated protein kinase alpha subunit AAK-2 is activated by AMP and functions to extend lifespan. [AMPK alpha2 (AAK2)] (Mus musculus) PubMed
75.
the first cloning, expression, and pharmacological characterization of members of a family of anion-selective acetylcholine receptor subunits(acetylcholine-gated chloride channel) (Mus musculus) PubMed
76.
data indicate that binding sites in three PDI domains, a, b', and a', contribute to efficient C-P4H tetramer assembly [phy-1] (Mus musculus) PubMed
77.
acts generally in gene expression (CYL-1, a cyclin); acts in heat-shock-inducible transcription (HSF-1 = heat-shock factor 1) (Mus musculus) PubMed
78.
dac-1 is expressed in a subset of sensory neurons including the AFD thermosensory neurons and is regulated by the TTX-1 OTX homeodomain protein. [dac-1] (Mus musculus) PubMed
79.
Both cof-2 mRNA and protein expression are developmentally regulated and both are affected by heat shock stress. (Mus musculus) PubMed
80.
Required for the movement of homologous pairs of vulva cells towards this midline position. (Plx-1) (Mus musculus) PubMed
81.
rde-3 is required for siRNA accumulation and for efficient RNAi in all tissues, and it is essential for fertility and viability at high temperatures. [rde-3] (Mus musculus) PubMed
82.
This syudy cloned Caenorhabditis elegans lev-8 and demonstrated that it encodes a novel nicotinic acetylcholine receptor (nAChR) subunit, which has functional roles in body wall and uterine muscles as part of a levamisole-sensitive receptor. (Mus musculus) PubMed
83.
CeBRC-2 regulates RAD-51 during homologous recombination and can also function independently of rad-51 in DSB repair processes (CeBRC-2 ). (Mus musculus) PubMed
84.
three different MPS subunits combine with KVS-1 to form both binary (MPS-1.KVS-1) and ternary (MPS-2.MPS-3.KVS-1) complexes in chemosensory neurons [MPS-2, MPS-3] (Mus musculus) PubMed
85.
aurora-B mediates phosphorylation of ZEN-4/MKLP1 in the completion of cytokinesis. [aurora B] (Mus musculus) PubMed
86.
This paper demonstrates a concentration-dependent relationship of C. elegans CYP35A1, A2, A5, and C1 gene expression in response to four organic xenobiotics, namely atrazine, PCB52, fluoranthene, and lansoprazole. [CYP35] (Mus musculus) PubMed
87.
Inhibition of PME-2 decreases embryonic survival rate of irradiated worms. (Mus musculus) PubMed
88.
C. elegans daf-6 encodes a patched-related protein required for lumen formation. (Mus musculus) PubMed
89.
The fos-1 is expressed in the anchor cell and controls invasion cell autonomously. (Mus musculus) PubMed
90.
RIM disrupts ELKS active zone targeting, suggesting a tight association between the two proteins in vivo. (RIM) (Mus musculus) PubMed
91.
The formation of the mitochondrial EF-Tu2/GTP/aminoacyl-tRNA ternary complex is probably supported by a unique interaction between the C-terminal extension of EF-Tu2 and the tRNA (EF-Tu2). (Mus musculus) PubMed
92.
The assembly of fibulin-1C and fibulin-1D in multiple locations is dependent upon the presence of hemicentin.[HEMICENTIN] (Mus musculus) PubMed
93.
Nup155 has an essential function in nuclear envelope formation in Caenorhabditis elegans embryos (Nup155). (Mus musculus) PubMed
94.
Data that cyclin D and other regulators of the G1/S transition coordinate key regulators of axis formation and sex determination with cell cycle progression to achieve the sexually dimorphic somatic gonadal precursor cell asymmetric division [cyclin D]. (Mus musculus) PubMed
95.
Caenorhabditis elegans Dcp8 is localized to distinct foci during embryogenesis. (Dcp8) (Mus musculus) PubMed
96.
The polyamine synthesis enzyme spermidine synthase (SPDS) from the model nematode Caenorhabditis elegans has been cloned and characterized.(SPDS) (Mus musculus) PubMed
97.
ACE-1 is an amphiphilic tetramer associated with a hydrophobic non-catalytic subunit, analogous to vertebrate T enzymes, whereas ACE-2 and ACE-3 are glycosylphosphatidylinositol-linked amphiphilic dimers[ACE-2] (Mus musculus) PubMed
98.
The C. elegans SIR-2.1, a member of the Sir-2 family of NAD(+)-dependent protein deacetylases, has been shown to regulate nematode aging via the insulin/IGF pathway transcription factor daf-16. (Mus musculus) PubMed
99.
In contrast to mitosis, both oocyte meiotic divisions proceeded normally following depletion of CENP-A, demonstrating the potential to uncouple assembly of outer-kinetochore proteins from CENP-A chromatin.[CENP-A] (Mus musculus) PubMed
100.
The expression of nephrocystin-1 is DAF-19 dependent, that its expression is restricted to ciliated sensory neurons, and that both NPH-1 and NPH-4 concentrate at the transition zones at the base of the cilia, but are not found in the cilium axoneme. (Mus musculus) PubMed
101.
Data suggest that inactive Ca2+/calmodulin-dependent protein kinase-II (CaMKII) forms tightly packed autoinhibited assemblies that convert upon activation into clusters of loosely tethered and independent kinase domains [CaMKII]. (Mus musculus) PubMed
102.
May function in hypodermal cell migration during ventral enclosure by maintaining levels of WSP-1. (Waspip-1 = WASP-interacting protein isoform 1) (Mus musculus) PubMed
103.
These results indicate that the actin-regulating activity of UNC-78 in cooperation with ADF/cofilin is essential for its in vivo function to regulate actin filament organization in muscle cells.(UNC-78) (Mus musculus) PubMed
104.
Fatty acid synthase (FAS) gene, encoding for a key enzyme involved in the biogenesis of membrane lipids in rapidly proliferating cells, is a conserved target of the p53 family throughout the evolution.[fasn-1] (Mus musculus) PubMed
105.
The cloning of daf-10 gene, this gene affects chemotaxis and are reqiured for intraflgellar transport. (Mus musculus) PubMed
106.
PA28 is likely to function in collaboration with Hsp90.(PA28) (Mus musculus) PubMed
107.
oxidative, osmotic, heat shock and starvation stresses induce germ cell apoptosis through a p53 and EGL-1 independent pathway [p53] (Mus musculus) PubMed
108.
Data suggest that a NURF-like complex including ISW-1 promotes the expression of vulval cell fates by antagonizing the transcriptional and chromatin-remodeling activities of complexes similar to Myb-MuvB/dREAM, NuRD and Tip60/NuA4 [NURF1, ISW1] (Mus musculus) PubMed
109.
These results suggest that AD-004 like protein (ADLP) is more likely a member of the adenylate kinase (AK6) family. (Mus musculus) PubMed
110.
Shal channels play a role as the predominant transient outward current in Caenorhabditis elegans muscle [Shl-1 and Shk-1] (Mus musculus) PubMed
111.
the critical residues essential for the unique serine specificity of C. elegans mitochondrial EF-Tu2 [EF-TU2] (Mus musculus) PubMed
112.
Results suggest that prohibitin 2 is involved in a previously uncharacterized pathway of multidrug resistance [prohibitin 2] (Mus musculus) PubMed
113.
The alternative-splicing defective-1(asd-1), encoding a new RNA-binding protein of the evolutionarily conserved Fox-1 family, as a regulator of the egl-15 reporter. (Mus musculus) PubMed
114.
most prominent expression of the protein is observed in the intestine, while muscle and epithelial cells express asp-6 to a lesser extent[aspartyl protease 6] (Mus musculus) PubMed
115.
analysis delineated a cohort of genes whose expression requires MPK-1 signaling in germ cells in the pachytene stage of meiosis I [MPK-1] (Mus musculus) PubMed
116.
A possible mechanism for cyclin E-Cdk2-dependent differentiation: the establishment of cortical polarity by the centrosome.[Cyclin E,Cdk2] (Mus musculus) PubMed
117.
C. elegans has at least two genes encoding functional d-aspartate oxidases (C47Ap and F18Ep) (Mus musculus) PubMed
118.
Inositol monophosphatase is required in central interneurons of the mature nervous system for correct localization of synaptic components and thus for normal behavior. [Inositol monophosphatase] (Mus musculus) PubMed
119.
expression of nex-2 & nex-4 was temporal, peaking at L1 stage followed by gradual decrease toward adult stage. NEX-2 & NEX-3 showed binding activities to phospholipids but not to phosphatidylcholine[nex-2, nex-3,nex-4] (Mus musculus) PubMed
120.
cloning of poly(ADP-ribose) glycohydrolases (pme-4). (Mus musculus) PubMed
121.
Caenorhabditis elegans expresses bona fide CRAC channels that require the function of Orai1- and STIM1-related proteins [orai1. STIM1, CRAC channel] (Mus musculus) PubMed
122.
Lag-3 has a role in regulating p53-mediated germ cell apoptotic response to DNA damage and expression of Ced-13 and Egl-1, downstream pro-apoptotic targets of the C. elegans p53 homolog Cep-1 [Lag-3] (Mus musculus) PubMed
123.
DYF-5 plays a role in the undocking of kinesin II from intraflagellar transport (IFT) particles and in the docking of OSM-3 onto IFT particles. (Mus musculus) PubMed
124.
afp-6 that both the transcript and the peptides are expressed in a single cell in the ventral ganglion. (Mus musculus) PubMed
125.
Characterize putative orthologs of human reduced folate carrier : folt-1 and folt-2 (Mus musculus) PubMed
126.
the molecular identification and characterization of PNGase (png-1, F56G4.5) from Caenorhabditis elegans. This enzyme released both high mannose- and complex-type N-glycans from glycopeptides and denatured glycoproteins. (Mus musculus) PubMed
127.
identified the sut-1 gene and found it encodes a novel protein. (Mus musculus) PubMed
128.
Here, we present cellular and biochemical analysis of Letm1 of a C. elegans mutant that could serve as a model for Wolf-Hirschhorn syndrome (Mus musculus) PubMed
129.
The fkb-6 gene is expressed in all stages of C elegans from embryo to adult with predominant expression being noted in the adult dorsal and ventral nerve cords. (Mus musculus) PubMed
130.
Transgenic mice expressing C. elegans n-3 fatty acid desaturase (fat-1) gene produce milk with elevated levels n-3 polyunsaturated fatty acids, altering growth rates/visual development in suckling pups. (Mus musculus) PubMed
131.
These results rule out the calmodulin/MLCK pathway as the missing regulator of cytokinesis in the C. elegans early embryo. [MLCK] (Mus musculus) PubMed
132.
Cadmium-induced germline apoptosis is dependent on the MAPK signaling pathways. (Mus musculus) PubMed
133.
Data show that the anti-obesity function of adipose (Adp) (worm Y73E7A.9, fly adp, and murine Wdtc1) is conserved from worms to mammals. [Adp] (Mus musculus) PubMed
134.
UNC-80 encodes a novel, but highly conserved, neuronal protein required for the proper localization of the NCA-1 and NCA-2 ion channel subunits. (Mus musculus) PubMed
135.
These results suggest that Galpha signaling and LET-99 control centration by regulating polarized actomyosin contraction.[GPA-16] (Mus musculus) PubMed
136.
prom-1 regulates the timely progression through meiotic prophase I [prom-1] (Mus musculus) PubMed
137.
ablation of BBS1 and BBS4 leads to alterations of s.c. sensory innervation and trafficking of the thermosensory channel TRPV1 and the mechanosensory channel STOML3[BBS1 and BBS4] (Mus musculus) PubMed
138.
Olrn-1 and voltage-activated calcium channels are mediators and targets of AWC signaling that act at the transition between a multicellular signaling network and cell-autonomous execution of the decision. (OLRN-1 PROTEIN, C.ELEGANS) (Mus musculus) PubMed
139.
Heat shock protein 16.2 reduce transfected abeta protein toxicittyby interacting directly with the Abeta peptide and altering its oligomerization pathways. [HSP16.2 protein] (Mus musculus) PubMed
140.
These results suggest that C. elegans COM-1 plays a role in the generation of ssDNA tails that can load RAD-51, invade homologous DNA tracts and thereby initiate recombination. (Mus musculus) PubMed
141.
RMD-1 functions in chromosome segregation in C. elegans embryos, possibly through the aurora B-mediated pathway. (Mus musculus) PubMed
142.
siRNA-mediated knockdown of a splice variant of the PK-A catalytic subunit gene causes adult-onset paralysis in C. elegans (Mus musculus) PubMed
143.
Long-chain polyunsaturated fatty acids are required for efficient synaptic vesicle recycling, probably by modulating synaptojanin localization at synapses.[Synaptojanin] (Mus musculus) PubMed
144.
intracellular trafficking of MIG-14 by AP-2 and retromer plays an important role in Wnt secretion. [AP-2] (Mus musculus) PubMed
145.
Regulation of the transport pathway between the Golgi apparatus and cell membrane may enable Wnt-producing cells to control the range of Wnt signaling in the tissue. [WNT] (Mus musculus) PubMed
146.
DYF-11 is likely associated with IFT complex B. Domain analysis using DYF-11 deletion constructs revealed that the coiled-coil region is required for proper localization and ciliogenesis. [DYF-11] (Mus musculus) PubMed
147.
analysis of 20 gene products that reproducibly enhanced misfolding of alpha-synuclein over the course of aging in human and C. elegans (Mus musculus) PubMed
148.
PBO-4 is a putative Na+/H+ ion exchanger expressed on the basolateral membrane of intestine, juxtaposed to the posterior body muscles. In pbo-4 mutants the extracellular space is not acidified and the muscles fail to contract. (PB0-4 PROTEIN, C ELEGANS) (Mus musculus) PubMed
149.
Polo kinases, via their polo box domains, bind to and regulate the activity of two key polarity proteins, MEX-5 and MEX-6.[DYRK2] (Mus musculus) PubMed
150.
CIN-4 and TOP-2 are topoisomerase II isoforms that perform separate essential functions in centromere structure and function.[CIN-4] (Mus musculus) PubMed
151.
meg-1 and meg-2 are expressed in the maternal germline and encode proteins that localize exclusively to P granules during embryonic germline segregation.[MEG-1, MEG-2] (Mus musculus) PubMed
152.
DEPS-1 is a key component of the P-granule assembly pathway and its roles include promoting accumulation of several mRNAs. (Mus musculus) PubMed
153.
CHE-12 and DYF-11 are conserved ciliary proteins that function cell-autonomously and are continuously required for maintenance of cilium morphology and function. [CHE-12 AND DYF-11] (Mus musculus) PubMed
154.
In summary, our studies suggest that LNP-1 plays a role in synaptogenesis by regulating vesicular transport or localization.(LNP-1 PROTEIN, C.ELEGANS) (Mus musculus) PubMed
155.
the extensive cys-loop LGIC gene superfamily observed for Caenorhabditis elegans namedlgc gene. (Mus musculus) PubMed
156.
NMR solution structure of a model mimicking the interaction of let-7 miRNA with its complementary site in the 3' untranslated region of the lin-41 mRNA (let-7 miRNA). (Mus musculus) PubMed
157.
Chromosome termini possess 3' G-strand overhangs and 5' C-strand overhangs; these two classes of overhangs are bound by two single-stranded DNA binding proteins, CeOB1 and CeOB2, which exhibit specificity for G-rich or C-rich telomeric DNA. [OB1,OB2] (Mus musculus) PubMed
158.
The heat shock transcription factor, hsf-1, is required for enhanced thermotolerance, suppression of proteotoxicity, and lifespan extension by dietary restriction. (Mus musculus) PubMed
159.
Data show that elipsa encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase, known to localize to cilia. (Mus musculus) PubMed
160.
The C. elegans glycosyltransferase BUS-8 has two distinct and essential roles in epidermal morphogenesis. (Mus musculus) PubMed
161.
The data suggest that MNP-1 is expressed in migrating muscle cells and localizes to the plasma membrane with the non-peptidase domain exposed to the extra-cellular environment.[MNP-1] (Mus musculus) PubMed
162.
Membrane trafficking regulated by ipla-1 provides a mechanism to control the cortical asymmetry of beta-catenin.[PLA-1] (Mus musculus) PubMed
163.
analysis of the expression pattern of the four mitochondrial adenine nucleotide transporter ant genes and their roles during the development of Caenorhabditis elegans [ANT-1.1, ant-1.2, ant-1.3, and ant-1.4] (Mus musculus) PubMed
164.
CRA-1 as a key component in promoting the assembly of the tripartite synaptonemal complex structure. (Mus musculus) PubMed
165.
Piwi acts upstream of an endogenous siRNA pathway in Tc3 silencing.[Piwi] (Mus musculus) PubMed
166.
Arsenite induced germline apoptosis through a MAPK-Dependent, p53-independent pathway in Caenorhabditis elegans. (Mus musculus) PubMed
167.
Expression of elt-5 and elt-6 increases during normal aging, and both of these GATA factors repress expression of elt-3, which shows a corresponding decrease in expression in old worms.[elt-5] (Mus musculus) PubMed
168.
ZOO-1 cooperates with the cadherin-catenin complex to dynamically regulate strong junctional anchorage to the actin cytoskeleton during morphogenesis. (Mus musculus) PubMed
169.
mRNA levels of several Dicer-regulated genes vary with changes in rncs-1 expression.[Dicer] (Mus musculus) PubMed
170.
The results presented in this study demonstrates voltage dependent inactivation of the nematode ICln splice variant IClnN2.[IClnN2] (Mus musculus) PubMed
171.
loss of UNC-64/DAT-1 interactions leads to enhanced synaptic dopamine release[syntaxin 1A or UNC-64 ] (Mus musculus) PubMed
172.
GLO-3 as a novel player in the formation of lysosome-related organelles (Mus musculus) PubMed
173.
GAP-3 is identified as the to date missing Caenorhabditiselegans member of the p120 RasGAP family.[GAP-3] (Mus musculus) PubMed
174.
[STG-2] In STG-2 mutants, AMPAR-mediated currents and worm behaviors are selectively disrupted despite apparently normal surface expression and clustering of the receptors. (Mus musculus) PubMed
175.
Sarcomeric actin organization is synergistically promoted by tropomodulin, ADF/cofilin, AIP1 and profilin in C. elegans(AIP1 and ADF/cofilin). (Mus musculus) PubMed
176.
Endogenous Q9 (coq-9) content of coq-8(ok840) knockouts was demonstrated to be about 7% of that found in the wild-type, indicating the basal biosynthesis rate is reduced in this strain. (Mus musculus) PubMed
177.
Purification, crystallization and X-ray structures of manganese superoxide dismutase2 and MnSOD3 from Caenorhabditis elegans (Mus musculus) PubMed
178.
SZY-20 opposes the Plk4-related kinase ZYG-1 to limit centrosome size [SZY-20, Plk-4] (Mus musculus) PubMed
Results suggest that pqbp-1.1 is involved in lipid metabolism of intestinal cells, and that dysfunction of lipid metabolism might underlie lean body, one of the most frequent symptoms associating with PQBP1-linked mental retrdation patients. (Mus musculus) PubMed
181.
SEPA-1 functions as a bridging molecule in mediating the specific recognition and degradation of P granule components by autophagy during C. elegans embryogenesis. (Mus musculus) PubMed
182.
mig-32 and spat-3 mutants are fertile, suggesting that Polycomb repression complex 1 (PRC1) function is not absolutely required in the germline for essential functions of PRC2 (Mus musculus) PubMed
183.
rictor mutants are developmentally delayed, small in size, lay an attenuated brood, and are short-lived, indicating that Rictor plays a role in partitioning calories between long-term energy stores and vital organismal processes [Rictor] (Mus musculus) PubMed
184.
findings indicate that SGK-1 is a mediator of Rictor activity; findings identify new physiological roles for TORC2, mediated by SGK, in regulation of C. elegans lipid accumulation and growth [Rictor] (Mus musculus) PubMed
185.
mutations in alpha-1,2-mannosidase I may extend longevity by modulating dietary restriction [alpha-1,2-mannosidase I ] (Mus musculus) PubMed
186.
A genetic screen identified DEX-1 and DYF-7, extracellular proteins required for dendritic tip anchoring, which act cooperatively at the time and place of anchoring.[DEX-1,DYF-7] (Mus musculus) PubMed
187.
A reduction in teg-4 activity reduces the splicing efficiency of targets involved in controlling the balance between proliferation and differentiation.[Teg-4] (Mus musculus) PubMed
188.
epg-1 encodes a divergent functional homolog of Atg13 in C. elegans.[Epg-1] (Mus musculus) PubMed
189.
Data demonstrate that klf-3 is a hitherto unrecognized key regulator of fat metabolism in C. elegans, and is critical for maintaining normal fatty acid composition by regulating genes involved in a fatty acid desaturation pathway [Klf-3]. (Mus musculus) PubMed
190.
NPF peptide from the nematode Caenorhabditis elegans was isolated and sequenced by tandem mass spectrometry[neuropeptide F] (Mus musculus) PubMed
191.
analysis of heme binding and catalytic activity of Caenorhabditis elegans and human dual oxidase 1 [DUOX1] (Mus musculus) PubMed
192.
in C. elegans, essential functions of Hop exist which apparently do not depend on the simultaneous binding of Hsp90 and Hsp70 to Hop.(Hop/Sti1) (Mus musculus) PubMed
193.
Data show that TBX-35 and CEH-51 have overlapping function in MS blastomere lineage development. (Mus musculus) PubMed
194.
GS28 and Ykt6 have a role in differentiation of stem cell-like epithelial cells (seam cells) and act redundantly for the proper expression of Golgi-resident proteins in C. elegans. [GS28, Ykt6] Results (Mus musculus) PubMed
195.
an interactive relationship between let-7 miRNA function and ribosomal protein RPS-14 in regulation of terminal differentiation that may help in understanding the mechanism of translational control by miRNAs (Mus musculus) PubMed
196.
Let-7 is the 1st known target of HBL-1 in C. elegans. A negative feedback loop mechanism controls let-7 and HBL-1 regulation. Let-7 (Mus musculus) PubMed
197.
Notch and Prospero repress proliferation following cyclin E overexpression in bristle cell lineage. [Prospero] (Mus musculus) PubMed
198.
pathways containing EGL-8-TPA-1-DKF-2 enable learning and behavioral plasticity by receiving, transmitting, and cooperatively integrating environmental signals targeted to both neurons and intestine [ DKF-2, DKF-2A, DKF-2B] (Mus musculus) PubMed
199.
reducing expression of a dual oxidase, Ce-Duox1/BLI-3, causes a decrease in reactive oxygen species production by Caenorhabditis elegans in response to E. faecalis (Mus musculus) PubMed
200.
LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans [let-7 microRNA] (Mus musculus) PubMed
201.
Genetic and cell biological interactions suggest that CALF-1 couples intracellular traffic to functional maturation of CaV2 presynaptic calcium channels. (Mus musculus) PubMed
202.
Knockdown of erasin, a platform for p97/VCP and ubiquilin binding, or knockdown of ubiquilin in human cells slowed degradation of two classical endoplasmic reticulum-associated protein degradation substrates.[erasin,Ubiquilin] (Mus musculus) PubMed
203.
A complex feedback loop between DAF-12 and the let-7-family miRNAs involving both the repression of DAF-12 by let-7-family miRNAs and the ligand-modulated transcriptional activation and repression of let-7-Fam miRNAs by DAF-12, is reported.[let-7 miRNA] (Mus musculus) PubMed
204.
NSF is not a required component of the cortical vesicle fusion machinery (Mus musculus) PubMed
205.
Unichrom binds to genome DNA at G-stretch and degradation of Unichrom is required for segregation of chromosomes. (Mus musculus) PubMed
206.
P16 is localized downstream of Alx1 in the PMC gene network, thereby linking the network to a specific "effector" protein involved in biomineralization (Mus musculus) PubMed
207.
The presence of secretory pathway Ca2+-ATPases (SPCA) and Ca2+ store in sea urchin sperm, which refills by SPCA-type pumps, is shown. (Mus musculus) PubMed
208.
a threefold increase in nucleolin leads to the complete absence of pre-rRNA maturation in addition to significant repression of RNA polymerase I transcription [ncl, =nucleolin] (Mus musculus) PubMed
209.
both XCAP-E and pEg7 are localized in the granular component of the interphase nucleolus (XCAP-E and pEG7) (Mus musculus) PubMed
210.
molecular cloning and biochemical characterization of two forms of Xenopus laevis UDP-GlcNAc: alpha6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II [GnT II-A, GNT II-B] (Mus musculus) PubMed
211.
Kir4.1 and Kir5.1 potassium channels bind with a heteromeric interaction that influences rectification, gating, and pH sensitivity [Kir4.1] (Mus musculus) PubMed
212.
These studies show that LKB1/XEEK1 is required for Wnt-beta-catenin signalling and provides novel insights into its role in vertebrate developmental patterning and carcinogenesis [LKB1(XEEK1)] (Mus musculus) PubMed
213.
Data suggest that the effects of Xrx1 on proliferation, neurogenesis and gene expression are restricted to the rostral region of the embryo, implicating this gene as an anterior regulator of neurogenesis [Xrx1]. (Mus musculus) PubMed
214.
xCIRP2 associates with specific mRNAs and can regulate the length of poly(A) tail in Xenopus oocytes [xCIRP2]; also xCIRP2 and ElrA may be involved in the regulation of mRNA stability at different steps [elavl1 or ElrA] (Mus musculus) PubMed
215.
results show that XCTK2 microtubule cross-linking activity is regulated by the importin alpha/beta and Ran pathway through a classical bipartite nuclear localization signal [CTK2] (Mus musculus) PubMed
216.
data demonstrate a positive role for protein phosphatase 2A:B56epsilon in the Wnt/beta-catenin signaling pathway [PP2A:B56epsilon] (Mus musculus) PubMed
217.
Data support a mechanism in which maternal XSOX3 inhibits beta-catenin-mediated axis specification by repressing expression of Xnr5 [XSOX3]. (Mus musculus) PubMed
218.
MECP2 along with methylated DNA and the SMRT complex has a role in cell fate decisions during primary neurogenesis in Xenopus [MeCP2] (Mus musculus) PubMed
219.
Cdc48/p97-Ufd1-Npl4 is an essential chaperone that regulates transformation of the microtubule structure as cells reenter interphase [AAA-ATPase Cdc48/p97] (Mus musculus) PubMed
220.
p42 MAPK and Cdc2 system normally generates an irreversible biochemical response from a transient stimulus, but the response becomes transient when positive feedback is blocked [cdc2, p42 MAPK] (Mus musculus) PubMed
221.
Hoxb4 directly induces the expression of FLASH, a component of the FAS-CAPSASE8 apoptotic pathway, in the notochord of embryos after neurulation. [Hoxb4][FLASH] (Mus musculus) PubMed
222.
the autoactivation mechanism of Aurora A [Aurora A] (Mus musculus) PubMed
223.
histone variant H2AZ stabilizes the histone octamer within the nucleosome [histone h2AZ] (Mus musculus) PubMed
224.
plays an essential role in the control of cell movement during gastrulation [platelet-derived growth factor receptor] (Mus musculus) PubMed
225.
Sox17 and beta-catenin interact to transcribe endodermal target genes [Sox17] (Mus musculus) PubMed
226.
CaMKIx plays some critical role in the late stages of embryogenesis of Xenopus laevis [CaMKIx] (Mus musculus) PubMed
227.
PTK7 is required for neural convergent extension and neural tube closure [ptk7] (Mus musculus) PubMed
228.
paraxial protocadherin can interact with the Xenopus Frizzled 7 receptor, and both proteins contribute to the development of separation [paraxial protocadherin] (Mus musculus) PubMed
229.
activity of both, Xenopus paraxial protocadherin and planar cell polarity signalling, is required to coordinate convergence and extension movements [paraxial protocadherin] (Mus musculus) PubMed
230.
Glut1 glucose transporter transmembrane segment 3 is an outer helix [Glut1] (Mus musculus) PubMed
231.
Kif2a is targeted to spindle poles by dynein/dynactin [Kif2a] (Mus musculus) PubMed
232.
Data show that two members of Par proteins, 14-3-3 (Par-5) and atypical PKC (PKClambda), regulate the serine/threonine kinase Par-1 to control Xenopus gastrulation [Par-1] (Mus musculus) PubMed
233.
Each of the SNAP-25 isoforms in the Xenopus pituitary and brain has a distinct function in cellular fusion processes including secretion, depending on the type of secreted hormone and/or the activity state of the cell.(snap-25a protein, Xenopus) (Mus musculus) PubMed
234.
Data suggest that Xenopus oocytes have a limited capacity to guide the assembly of nicotinic acetylcholine receptor alpha7 subunits, but not 5-hydroxytryptamine 3A subunits to homopentamers [nicotinic acetylcholine receptor alpha7]. (Mus musculus) PubMed
235.
A dominant-negative mutant of xAC7 induced hormone-independent oocyte maturation and accelerated progesterone-induced oocyte maturation; findings suggest xAC7 is a major component of the G2 arrest mechanism in Xenopus oocytes. [adenylyl cyclase 7 (AC7)] (Mus musculus) PubMed
236.
Novel conditional and hypomorphic alleles of smad2 were generated. (Mus musculus) PubMed
237.
ZPA has a role in egg envelope hardening after proteolysis [egg envelope component ZPA] (Mus musculus) PubMed
238.
Oocytes expressing Cx26 exhibited large membrane conductances over a broad range of hyperpolarizing and depolarizing membrane potentials (connexin 26). (Mus musculus) PubMed
239.
At late tail bud stages flotillin1B expression is more restricted in the dorsal neural tube and head sensory structures. (flotillin 1B) (Mus musculus) PubMed
240.
Myo3A plays a role in the morphogenesis and maintenance of calycal processes of vertebrate photoreceptors [myo3a] (Mus musculus) PubMed
241.
May be an important factor for skin maturation, may also serve as a good marker for epidermis maturation. (Nkx-2.3) (Mus musculus) PubMed
242.
EDEN-BP-dependent post-transcriptional regulation of gene expression is required for the process of somitic segmentation.(EDEN-BP) (Mus musculus) PubMed
243.
interaction of tau with microtubules may modify local mechanical properties of individual microtubules and play a crucial role in the remodeling of the microtubules cytoskeleton during neuronal plasticity [tau] (Mus musculus) PubMed
244.
Purification, crystallization and preliminary X-ray analysis of the N-terminal domain of NO38 [NO38, also called nucleophosmin or B23] (Mus musculus) PubMed
245.
[NRP-1; BruL-1 or Etr-1] Nrp-1 is expressed in both stem cells and mitotic precursors in developing Xenopus retina. BruL-1 is a good marker of post-mitotic retinal neurons. (Mus musculus) PubMed
246.
activin a has a role in development of tooth and eye in Xenopus [Activin A] (Mus musculus) PubMed
247.
analysis of activin-like kinase receptor-4 (ALK4) developmental expression in Xenopus laevis [ALK4] (Mus musculus) PubMed
248.
Xenopus laevis CYP17 regulates androgen biosynthesis independent of the cofactor cytochrome b5 [CYP17, cytochrome b5] (Mus musculus) PubMed
Results suggest that one functional subunit can regulate the pH-dependent gating of the Kir1.1 channel, and that channel sensitivity to pH increases with additional subunits. (Mus musculus) PubMed
251.
ionotropic glutamate receptor 3 has specific N-terminal domain regions that form the subunit oligomerization interfaces that control subtype-specific receptor assembly [GLUR3] (Mus musculus) PubMed
252.
rapid movements of TFIIIA side chains permit them to make fluctuating contacts with adjacent bp in the DNA of the gene (5S rRNA) (Mus musculus) PubMed
253.
may mediate neurogenesis control by maintaining splicing and translational silencing in undifferentiated neural cells (SRp38) (Mus musculus) PubMed
254.
Data show that the anaphase-promoting complex (APC/C)-Cdc20 can mediate cyclin B degradation in cytostatic factor-arrested Xenopus eggs and extracts [Cdc20, cyclin B]. (Mus musculus) PubMed
255.
Wnt-4 is required for eye development in Xenopus laevis. (Mus musculus) PubMed
256.
The spinophilin (SPL), which binds the third intracellular loop (3iL) of several GPCRs, binds the N-terminal domain of RGS2. (Mus musculus) PubMed
257.
a novel function of xPontin and xReptin as co-repressors in the c-Myc/Miz-1 pathway [Miz-1] (Mus musculus) PubMed
258.
solution structure of Quaking protein [Quaking protein ] (Mus musculus) PubMed
MNAR participates in G protein-regulated meiosis in Xenopus laevis oocytes [MNAR, also called PELP1] (Mus musculus) PubMed
261.
Xenopus beta2-microglobulin mRNA is expressed ubiquitously with highest expression in intestine, spleen, and thymus, correlating well with classical class Ia expression [beta2-microglobulin] (Mus musculus) PubMed
262.
Eg5 can tether microtubule plus-ends, suggesting an additional microtubule-binding mode for Eg5 [Eg5] (Mus musculus) PubMed
263.
Gonadal proopiomelanocortin convertase gene expression is demonstrated in Xenopus laevis. (prohormone convertase 1, prohormone convertase 2) (Mus musculus) PubMed
264.
The CaBP1-binding sites at the C terminus of TRPC5 are closely localized, but not identical, to CaM-binding sites. We conclude that TRPC5 is a Ca2+-regulated channel, and its activity is negatively controlled by CaBP1.[TRPC5] (Mus musculus) PubMed
265.
molecular cloning of connexin40.4; during Xenopus laevis development, connexin40.4 was first expressed after the mid-blastula transition [connexin40.4] (Mus musculus) PubMed
266.
investigated the role of steroid receptor coactivator 3 (SRC3) in gene activation by thyroid hormone receptor (TR) in vivo during development(steroid receptor coactivator-3) (Mus musculus) PubMed
267.
PDGFRalpha-mediated cell survival requires PLCgamma and phosphatidylinositol 3-kinase signaling, and that PDGFRalpha with binding sites for these two signaling factors is sufficient for this activity (Mus musculus) PubMed
268.
Xenopus NKCC is stimulated by insulin and genistein in a synergistic manner (Mus musculus) PubMed
269.
isolation of Xmad1, Xmad3 and Xmnt, novel genes belonging to the Mad family and description of their temporal and spatial expression patterns during embryogenesis [mad3, mnt mad1] (Mus musculus) PubMed
270.
A novel Daple-like protein, a positive regulator of the Wnt/beta-catenin pathway, named as xDal (Xenopus Daple-like)was identified.(xDal) (Mus musculus) PubMed
271.
Data show that Esr1 and Esr10 are differentially regulated both in terms of Notch input and its interaction with heterologous factors [Esr1]. (Mus musculus) PubMed
272.
TFAP2alpha is important for ectoderm development and is required for the molecular linkage between the epidermis and neural crest in the Xenopus embryo. (Mus musculus) PubMed
273.
Down-regulation of TCOF1 (treacle) expression in X. laevis oocytes resulted in inhibition of rDNA gene transcription and suggests evolutionary conservation of the function of treacle in ribosomal RNA biogenesis in higher eukaryotes [TCOF1] (Mus musculus) PubMed
274.
calcium-activated CaMKII triggers exit from meiosis II by sensitizing the APC/C inhibitor XErp1 for polo-like kinase 1 (Plx1)-dependent degradation [XErp1] (Mus musculus) PubMed
275.
Agrin regulates neurite extension and provide evidence for an unanticipated role of agrin in growth-cone steering in developing neurons. [ARGIN] (Mus musculus) PubMed
276.
Furthermore, while activities to process procaspase-8 and procaspase-9 appeared in SAMDC-overexpressed apoptotic embryos, the activity to process procaspase-8 did not appear in p53-overexpressed apoptotic embryos. (Mus musculus) PubMed
277.
These results suggest that pEg3 might play a role at the cell cortex during mitosis.[Protein kinase pEg3] (Mus musculus) PubMed
278.
complex containing Smicl and the newly induced Xlim1 induces expression of Chordin [Smicl] (Mus musculus) PubMed
279.
SOX7 and SOX18b are essential regulators of cardiogenesis in Xenopus. [Sox18beta] (Mus musculus) PubMed
280.
Blocking mitotic entry by adding the catalytic subunit of protein kinase A results in increased wee1 Ser549 phosphorylation and maintenance of cdc25C. (protein kinase A) (Mus musculus) PubMed
281.
Nrarp independently regulates canonical Wnt and Notch signalling by modulating LEF1 and Notch protein turnover, respectively.[Nrarp (Notch-regulated ankyrin repeat protein)] (Mus musculus) PubMed
282.
The Werner syndrome protein is a RecQ-type DNA helicase, which seems to participate in DNA replication, double-strand break (DSB) repair, and telomere maintenance. (Mus musculus) PubMed
283.
identified 71 transcripts that are upregulated by Mixer or Sox17beta[Mixer and Sox17beta (Mus musculus) PubMed
284.
Noelin-4 protein is glycosylated and secreted and that it interacts with Noelin-1, an isoform previously found to promote differentiation in neuralized animal caps [Noelin-4]. (Mus musculus) PubMed
285.
Lox-related enzymes are required for the proper formation of the ECM during X. laevis development.[Xlox-1] [Xlox-3] (Mus musculus) PubMed
286.
[Neuroserpin] Xenopus neuroserpin may play an important physiological role, e.g. as a serine protease inhibitor during development, and for proper neuronal and neuroendocrine cell functioning. (Mus musculus) PubMed
287.
The alpha-neurexins are differentially regulated during development with respect to gene temporal and spatial expression and alternative splicing. [nrxnI alpha, nrxnII alpha, nrxnIII alpha] (Mus musculus) PubMed
288.
MRN complex is not required for efficient and accurate NHEJ-mediated repair of DSBs in this vertebrate system (Mre11). (Mus musculus) PubMed
289.
We cloned the full-length gene encoding Xenopus separase from an oocyte cDNA library. Purified xSeparase can cleave the human alpha-kleisin subunit of cohesin in vitro but cannot bind to hSecurin when these two proteins are coexpressed in 293T cells. (Mus musculus) PubMed
290.
[calretinin]Most calcium-binding proteins calretinin-containing spinal cord neurons were located in the superficial dorsal gray field, but with distinct topography. (Mus musculus) PubMed
291.
The role of Xorbit in spindle assembly and function is studied. (Mus musculus) PubMed
292.
These results demonstrate for the first time a PKA-restrictive and a PKA-permissive phase in oocyte maturation [Protein kinase A] (Mus musculus) PubMed
293.
X-Delta-2 is involved in the migration of the cranial placodes cells, as well the migration of the cranial neural crest cells during neurogenesis.(X-Delta-2) (Mus musculus) PubMed
294.
These results demonstrate that a reversible Pum2 interaction controls RINGO/Spy mRNA translation and, as a result, CPEB-mediated cytoplasmic polyadenylation. (Mus musculus) PubMed
295.
embryonic expression pattern of the SLC20A1; SLC20A1 mRNA is expressed in the somitic mesoderm and lower level of expression is detected in the neural tube, eye, and neural crest cells [SLC20A1] (Mus musculus) PubMed
296.
Dissociated by RanGTP, NuSAP may aid to maintain spindle integrity by stabilizing and cross-linking microtubules around chromatin. RANFRP AND NuSAP) (Mus musculus) PubMed
297.
XlHMGA2alpha appears to be preferentially expressed during oogenesis and after midblastula transition, whereas XlHMGA2beta expression predominates after neurulation, suggesting an individual transcriptional regulation. (Mus musculus) PubMed
298.
Bowline is a novel protein interacting with Groucho/TLE and may play a role in somitogenesis (bowline protein) (Mus musculus) PubMed
299.
xSyn4 and fibronectin cooperate with xFz7 and Wnt in the specific activation of the non-canonical Wnt pathway.[Syndecan-4] (Mus musculus) PubMed
300.
MELK phosphorylation by MPF and MAPK enhance its activity during M-phase [MELK, MPF, MAPK] (Mus musculus) PubMed
301.
These results show that somitogenesis and patterning of the anteroposterior axis are closely linked involving Hox genes and X-Delta-2, suggesting the existence of a coordination mechanism between somite formation and axis patterning. [X-Delta-2] (Mus musculus) PubMed
302.
PCNS (Protocadherin in Neural crest and Somites), a novel Pcdh in Xenopus, is initially expressed in the mesoderm during gastrulation, followed by expression in the cranial neural crest and somites. [PCNS] (Mus musculus) PubMed
303.
results confirm that the level of expression of both TOPK and DYRK1A is significantly higher in oocytes induced to mature in insulin than in oocytes that are induced to mature by injection of Val 12-ras-p21 [TOPK] (Mus musculus) PubMed
304.
Required for normal vascular development in the frog embryo and has properties consistent with a role during normal and pathological angiogenesis. (apelin or Apln) (Mus musculus) PubMed
305.
results support a recent proposal that AKAP participates in regulating protein kinase A activity independently from cAMP [A kinase anchoring protein, AKAP, portein kinase A type II] (Mus musculus) PubMed
306.
These data suggest that pEg6 acts as a vegetally localized factor contributing to the actin nucleation process during Xenopus early development.(EG6 PROTEIN, XENOPUS) (Mus musculus) PubMed
307.
metastasis-associated kinase is a novel regulator of Wnt signaling during morphogenetic movements, and eye and brain development in Xenopus embryos. (metastasis-associated kinase--MAK) (Mus musculus) PubMed
308.
Nup107-160 complex is dynamic in mitosis and that it promotes spindle assembly in a manner that is distinct from its functions at interphase nuclear pores.[Nup107, Nup160] (Mus musculus) PubMed
309.
We show here that EDEN-BP is able to oligomerize. A 27-amino-acid region of EDEN-BP was identified as a key domain for oligomerization.Impairing oligomerization specifically abolished EDEN-dependent deadenylation.[EDEN-BP (EDEN-binding protein)] (Mus musculus) PubMed
310.
results provide the first evidence that Neogenin acts as an axon guidance molecule in vivo and support a model whereby Neogenin-expressing axons respond to a combination of attractive and repulsive cues as they navigate their ventral trajectory [Neogenin] (Mus musculus) PubMed
311.
Xenopus laevis POU91 protein, an Oct3/4 homologue, regulates competence transitions from mesoderm to neural cell fates (Mus musculus) PubMed
312.
We identify Partner of paired (Ppa) as the F-box component of a modular E3 ligase, and show that it is expressed in neural crest-forming regions, and that it binds to and promotes ubiquitin-mediated proteasomal degradation of Slug (Mus musculus) PubMed
313.
although Smad4alpha and Smad4beta may have similar activities, they are differentially utilized during frog embryogenesis, with only Smad4beta being essential for mesoderm induction [Smad4alpha, Smad4beta] (Mus musculus) PubMed
314.
Proper expression of XTsh1 is essential for segmentally restricted gene expression in the posterior brain and CNC and suggest for the first time that teashirt genes act as positional factors also in vertebrate development.[XTsh1] (Mus musculus) PubMed
315.
Grhl3 promotes superficial gene expression in the deep layer of the epidermis. (Grhl3,grainyhead-like 3) (Mus musculus) PubMed
316.
Cyclin B dissociation from CDK1 precedes cyclins B degradation upon CDK1 inactivation in mitotic embryo extracts and that proteasome proteolytic activity is dispensable for both activation and inactivation of CDK1 in such extracts. [Cyclin B2, MPF,] (Mus musculus) PubMed
317.
Results indicate PN-1 could have a natriuretic role by inhibiting prostasin activity. Aldosterone and TGF-beta reciprocally regulate expression of PN-1. PN-1 could represent a factor that contributes to regulation of ENaC activity [prostasin and PN-1]. (Mus musculus) PubMed
318.
ET receptors in pigment cells of vertebrate species were identified by RT-PCR assays, and the differential expression of the various subtypes in each species was compared by quantitative PCR.(Endothelin receptor Ax, Endothelin receptor C] (Mus musculus) PubMed
319.
Emi2 plays an essential role in meiotic but not mitotic cell cycles [emi2] (Mus musculus) PubMed
320.
Several CKI isoforms including CKIalpha and Gish/CKIgamma can phosphorylate the Wg coreceptor Arrow (Arr), which may account, at least in part, for their positive roles in the Wg pathway. (Mus musculus) PubMed
321.
A novel member of the hairy/Enhancer of split [E(spl)] gene family in Xenopus, XHes2, as a regulator to bias retinal precursor cells towards a glial fate, was identified. (Mus musculus) PubMed
322.
identify inositol 1,4,5 trisphosphate receptor type 1 (IP3R1) phosphorylation by M-phase kinases as a regulatory mechanism of IP3R1 function in eggs that serves to optimize internal calcium release at fertilization [IP3R1]. (Mus musculus) PubMed
323.
Whole-mount in situ hybridization analysis showed that rhoB is expressed in the dorsal marginal zone early in gastrula then in the dorsal midline and at mid-neurula stages, rhoB expression extends to the CNS, presomitic mesoderm and somites.[RhoB protein] (Mus musculus) PubMed
324.
high level of sustained maternal Jun NH2-terminal kinase activity in early Xenopus embryos may provide a timing mechanism for controlling the dorsal axis formation[Jun NH2-terminal kinase ] (Mus musculus) PubMed
325.
report the identification and developmental expression of Xenopus laevis hmga2beta (Xlhmga2beta) (Mus musculus) PubMed
326.
B56epsilon regulatory subunit of protein phosphatase 2A (PP2A) is involved in Xenopus eye induction and subsequent eye field separation. [PP2A:B56epsilon] (Mus musculus) PubMed
327.
Enhanced expression of SCP2 in Xenopus embryos leads to an extensive loss of linker phosphorylation of Smad1 and Smad2. (Mus musculus) PubMed
328.
Maskin phosphorylation-dephosphorylation also oscillates with the cell cycle and is controlled by the kinase CDK1 and the phosphatase calcineurin [CDK1] (Mus musculus) PubMed
329.
These observations identify PP2A/B56delta as a central checkpoint effector and suggest a mechanism for controlling 14-3-3 interactions to promote mitosis. (Mus musculus) PubMed
330.
By the cotransport mechanism about 35 water molecules were transported for each sugar molecule by a mechanism within the GLUT2 [GLUT2]. (Mus musculus) PubMed
331.
These results suggest that XSu(H)2 is involved in mesoderm formation and the cell movement of gastrula embryos in a different manner from the Notch signaling target gene, XESR-1-mediated Notch signaling pathway. [XSu(H)2 protein] (Mus musculus) PubMed
332.
These results suggest that XSu(H)2 is engaged in the cell fate decision during gastrulation through the gene expression of the Xoct25/91-mediated pathway.[Suppressor of hairless 2] (Mus musculus) PubMed
333.
These findings demonstrate that the spatial localization of type II PKA to growth cone filopodia plays an important role in the regulation of growth cone motility and guidance by cAMP.[type II protein kinase A] (Mus musculus) PubMed
334.
The data suggest that EphA4 activation sequesters active Cdc42 and in this way down-regulates cell-cell adhesion.[Pak1, Cdc42] (Mus musculus) PubMed
335.
Rx1 and Pax6 differentially modify the ability of eye field precursors to produce different neurotransmitter subtypes of amacrine cells. (RX1, Pax6) (Mus musculus) PubMed
336.
Galphai3-induced activation of G protein-activated K+ channels by Gbetagamma, demonstrated in intact cells, supports the hypothesis that Galphai regulates ion gating under physiological conditions [Galphai3 and G protein beta/gamma]. (Mus musculus) PubMed
337.
Study isolated 35-kDa Ca-dependent lectin, XCL-1 from adult serum and a cDNA for an XCL-1-related protein, XCL-2; XCL-2gene expression was significantly increased in the regenerating tails, suggesting its role in tail regeneration.[XCL-1, XCL-2 protein] (Mus musculus) PubMed
338.
over-expression of PHD47 rescued the small eye abnormality caused by xSiah2 [HIF-prolyl 4-hydroxylase] (Mus musculus) PubMed
339.
Full-length Eg5 moves processively and stepwise along microtubule bundles. Eg5 typically detached from microtubules before stalling. This behavior may reflect a regulatory mechanism important for the role of Eg5 in the mitotic spindle. (Mus musculus) PubMed
340.
Xenopus Gef (XGef), a Rho-family guanine-exchange factor, influences the activating phosphorylation of CPEB. (Xgef) (Mus musculus) PubMed
341.
the identification and functional characterization of Xenopus Tetraspanin-1 (xTspan-1). (Mus musculus) PubMed
342.
The ontogenetic patterns of Aro, Srd5a1 and Srd5a2 suggest that these genes are involved in sexual differentiation of gonads and brain already in early developmental stages.[srd5a1 and srd5a2] (Mus musculus) PubMed
343.
Overexpression of Nrl dramatically increased the number of lens fibers, both directed photoreceptor precursors to become rods at the expense of cones. (Nrl = leucine zipper transcription factor) (Nr2e3 = nuclear receptor subfamily 2, group E, member 3) (Mus musculus) PubMed
344.
In Xenopus oocytes, p42 MAPK interacts with hypophosphorylated Cdc25 before meiotic induction. During meiotic induction, p42 MAPK phosphorylates Cdc25 at three sites, increasing Cdc25's phosphatase activity. [p42 MAPK] (Mus musculus) PubMed
345.
results clarify the direct link of the classical Mos-MAPK pathway to Erp1 in meiotic arrest of vertebrate oocytes [Erp1] (Mus musculus) PubMed
346.
xEIAP/XLX is physiologically phosphorylated by p42MAPK in Xenopus unfertilized eggs[p42MAPK and xEIAP] (Mus musculus) PubMed
347.
Vg1 and VegT can repress the ability of dorsal-animal retinogenic blastomeres to form retina, converting the lineage from neural/retinal to non-neural ectodermal and endo-mesodermal fates. [VegT] (Mus musculus) PubMed
348.
Casein kinase I and FGF signalling converge on an antagonistic regulation of FoxG1, which in turn controls neurogenesis in the forebrain. (Mus musculus) PubMed
349.
Report demonstrates that the neuroectoderm/mesoderm boundary is controlled by the chromatin remodeling ATPase CHD4/Mi-2beta. [CHD4 protein] (Mus musculus) PubMed
350.
This investigation reveals important role of xVAP019 in embryonic development.(xVAP019) (Mus musculus) PubMed
351.
Data show that ATM (ataxia-telangiectasia mutated) regulates Xenopus TopBP1 by phosphorylating serine 1131 and thereby strongly enhancing association of TopBP1 with ATR(ATM and Rad3-related) [TopBP1]. (Mus musculus) PubMed
352.
stimulation of ENaCs by EPA occurs via SGK in membrane-bound compartments containing an AKAP, activated PKA, and a phosphodiesterase [AKAP] (Mus musculus) PubMed
353.
findings implicate xGLUT1 as an important player during gastrulation cell movement in Xenopus [GLUT1] (Mus musculus) PubMed
354.
Analysis of kinetics and substrate specificity of SLC20A1. (Mus musculus) PubMed
355.
Lysine-specific demethylase gene was cloned and its expression in metamorphosis examined; study concluded that LSD1 participates in the regulation of metamorphosis by thyroid hormone- transcriptional factor-induced chromatin remodeling. [LSD1 protein] (Mus musculus) PubMed
356.
homomeric and heteromeric Kir2.x channels are activated by beta(3)-adrenoceptors via different protein kinase-dependent pathways: Kir2.1 subunits are modulated by PKC, whereas Kir2.2 is modulated by protein kinase A. [Kir2.2][adrenergic beta3 receptor] (Mus musculus) PubMed
357.
findings show that neither cyclin B2 degradation nor Thr-161 dephosphorylation participates directly in CDK1 inactivation as measured by histone H1 kinase decline upon the exit from mitotic M-phase in Xenopus embryo extract[CDK1] (Mus musculus) PubMed
358.
TOPK is required for oocyte maturation induced by wild-type p21. [TOPK] (Mus musculus) PubMed
359.
these results suggest that the Kir4.1-Kir5.1 but not the homomeric Kir4.1 channel is strongly inhibited by PKC activation.[Kir4.1] (Mus musculus) PubMed
360.
These studies support a model in which vertebrate Ctr1 functions as a key regulator of the differentiation capacity of both stem and progenitor cell populations.[Ctr1] (Mus musculus) PubMed
361.
The cloning, expression, purification, and antibody production of a PNAS-4 homolog (named xPNAS-4) from Xenopus laevis were reported.(xPNAS-4) (Mus musculus) PubMed
362.
Ceramide mediates TNF-alpha inhibition of the renal epithelial sodium channel (ENaC) via a pathway associated with PKC-dependent externalization of phosphatidylserine [ENaCand protein kinase C]. (Mus musculus) PubMed
363.
interaction of the 9-1-1 complex (Rad9-Hus1-Rad1) with the BRCT I-II region of TopBP1 is necessary for binding of ATR-ATRIP to the ATR-activating domain of TopBP1 and the ensuing activation of ATR [TOPBP1] (Mus musculus) PubMed
364.
Cloning and expression studies of the DRR1 gene during embryo development (DRR1). (Mus musculus) PubMed
365.
Cleavage of Geminin by caspase-3 is not relevant to its function as regulator of DNA synthesis, suggesting that its cleavage may be relevant to its role in differentiation.[Caspase-3] (Mus musculus) PubMed
366.
Custom-tailored current of Kv2.1/Kv8.2 functionally contributes to photoreception, which why mutations of Kv8.2 lead to a genetic visual disorder. [KV8.2] (Mus musculus) PubMed
367.
Rho GTPases can regulate the expression of XSnail2 during neural crest ontogeny (Mus musculus) PubMed
368.
These data suggest a model in which ERK phosphorylation must be spatially coupled to integrin-mediated DIM-7 activation to make a complex that can be imported efficiently.[Dim-7] (Mus musculus) PubMed
369.
Xenopus laevis microRNAs miR-15 and miR-16 restrict the size of the organizer by targeting the Nodal type II receptor Acvr2a [Acvr2a & Nodal & miRNAs too?] (Mus musculus) PubMed
370.
Cep57/Translokin is required for stable microtubule attachments at the kinetochore and at the centrosome. (Mus musculus) PubMed
371.
A phosphorylated protein with molecular mass of 25,000 (pp25) derived from Xenopus laevis vitellogenin B1 may play different role from those of yolk proteins lipovitellin and phosvitin in X. laevis oocytes and developing embryos. (Mus musculus) PubMed
372.
Here we identify Xenopus laevis Tipin as a substrate for cyclin E/cyclin-dependent kinases 2 that is phosphorylated in interphase and undergoes further phosphorylation upon entry into mitosis. (Mus musculus) PubMed
373.
Sos (Son of Sevenless Proteins) forms part of a multiprotein complex vital for intracellular signaling via LV1 (lipovitellin 1) in xenopus ooxytes. (Mus musculus) PubMed
374.
a mutation in the Sall1 repression motif disrupts recruitment of the nucleosome remodeling and deacetylase complex and repression of Gbx2 (Mus musculus) PubMed
375.
Immunohistochemical techniques were employed to investigate orexin-A-like and orexin receptor 1 (OX1R)-like immunoreactivities in the Xenopus pituitary gland.[Orexin A, orexin receptor 1] (Mus musculus) PubMed
376.
Ubp-M regulates Hox gene expression through H2A deubiquitination and that blocking the function of Ubp-M results in defective posterior development in Xenopus laevis [Ubp-M] (Mus musculus) PubMed
377.
Characterization of the PL-I-related SP2 protein from Xenopus.[Sp2] (Mus musculus) PubMed
378.
SHP-2 functions within the FGF/MAPK pathway to maintain survival of proliferating populations of cardiac progenitor cells.[SHP-2, also known as PTPN11] (Mus musculus) PubMed
379.
prospective neural cells are poised to respond to Smad2 and Smad1 signals to adopt mesodermal and non-neural ectodermal fates even at gastrula stages[ Smad1 and Smad2] (Mus musculus) PubMed
380.
Bod1 is a novel kinetochore protein that is required for the detection or resolution of syntelic attachments in mitotic spindles.[Bod1] (Mus musculus) PubMed
381.
CPEB, partnered with several highly conserved RNA-binding partners, inhibits protein synthesis in oocytes using a novel pairing of 4E-T and eIF4E1b [4E-T] (Mus musculus) PubMed
382.
Xhes6 is essential for XmyoD induction and acts by relieving Groucho-mediated repression of gene expression.[Hes6, MyoD] (Mus musculus) PubMed
383.
Intracellular Ca(2+) plays a role as the second messenger in hypotonic stress-induced Na(+) transport by stimulating transcription of SGK1 and ENaC subunits [SGK1 and ENaC]. (Mus musculus) PubMed
384.
These results suggest that xRic-8 is participating in the immature oocyte by keeping Gsalpha-Gbetagamma-AC signaling complex in an activated state and therefore maintaining G2 arrest.[xRic-8, Gsalpha] (Mus musculus) PubMed
385.
Results report that WNK3, another member of the WNK kinase family expressed by distal tubule cells, interacts with WNK4 and WNK1 to regulate NCC in both human kidney cells and Xenopus oocytes [NCC]. (Mus musculus) PubMed
386.
demonstrated a critical requirement for XHSP27 in developing cardiac and skeletal muscle tissues[Hsp27] (Mus musculus) PubMed
387.
Partitioning-defective (PAR1) is a conserved serine/threonine protein kinase implicated in the establishment of cell polarity [PAR1] (Mus musculus) PubMed
388.
CDC2 protein kinase, Xenopus. CDC2 phosphoylation of BubR1 controls spindle checkpoint arrest and plk-mediated formation of the 3F3/2 epitope. (Mus musculus) PubMed
389.
Sox3 genomic elements were identified and characterized and an element required for BMP-mediated repression via Vent1 and Vent2 proteins was identified through the use of transgenesis and computational analysis.[Vent1] (Mus musculus) PubMed
390.
SUR1 and SUR2A randomly coassemble into functional K(ATP) channels [SUR1 and SUR2A] (Mus musculus) PubMed
391.
We conclude that the SCFskp2 complex has functions in the control of neuronal differentiation additional to its role in cell cycle regulation. (SKP2 PROTEIN, XENOPUS) (Mus musculus) PubMed
392.
TGIF2 is the molecular link between dorsoventral patterning of the endoderm and pancreatic specification.[TGIF2, Gata5] (Mus musculus) PubMed
HVA L-type channel kinetics differ in relation to environmental changes in cellular secretory state, via intracellular Ca(2+)-buffering. Occurrence of LVA Ca(2+) channels depend on environment controlled channel gene expression [calcium channel, L-type]. (Mus musculus) PubMed
395.
Analysis of collectrin expression in pronephroi at a variety of embryonic stages indicates that this gene is expressed at very high levels throughout the pronephric system, including proximal and distal segments and the Wolffian duct (collectrin). (Mus musculus) PubMed
396.
suggest a role for importin alpha in regulating lamin assembly and possibly modulating the interactions of lamins with lamin-binding proteins[ lamin b3] (Mus musculus) PubMed
397.
We propose that the main function of NEDD1 in Xenopus is in microtubule organization.(NEDD1 protein, Xenopus) (Mus musculus) PubMed
398.
We have defined the proportion of GnRHRs at the cell surface. (GnRH receptor) (Mus musculus) PubMed
399.
defined regions of Nup53 that bind to neighboring nucleoporins as well as those domains that target Nup53 to the nuclear pore complex (Nup53) (Mus musculus) PubMed
400.
findings indicate that Activin/nodal signaling participates in regulation of XPAPC expression through a Smad binding element within the XPAPC promoter [XPAPC] (Mus musculus) PubMed
401.
The amphibian sequence encodes a protein that is indeed a functional Na(+)/iodide symporter (NIS protein) in X. laevis, as well as R. catesbeiana [NIS protein]. (Mus musculus) PubMed
402.
Cdk11 is responsible for RanGTP-dependent MT stabilization around chromosomes; this local stabilization is essential for normal rates of spindle assembly and spindle function.(CDK11 PROTEIN, XENOPUS) (Mus musculus) PubMed
403.
Interactions between extracellular matrix molecule laminin beta2 and CaV2.2 calcium channel/Cacna1B regulate connectivity in the developing nervous system.(Cav2.2; cacna1B channel; calcium channel, voltage-dependent, N type, alpha 1B subunit) (Mus musculus) PubMed
404.
Results suggest that Mitfalpha-M is involved in the regulation of melanosome transport and the level of dendricity in melanophores. (Mus musculus) PubMed
405.
We conclude that importin beta, human or Xenopus, is an authentic negative regulator of nuclear assembly and, presumably, spindle assembly. (Importin beta, Xenopus) (Mus musculus) PubMed
406.
Data show that HMGA2, a member of the HMGA sub-family of HMG proteins, has a critical function in cardiogenesis. (Mus musculus) PubMed
407.
MKP3 can act to enhance DAT function and identifies MKP3 as a phosphatase involved in regulating dynamin-dependent endocy [DUSP6; SLC6A3] (Mus musculus) PubMed
408.
Pituitary adenylate cyclase-activating polypeptide regulates brain-derived neurotrophic factor exon IV expression through the VPAC1 receptor in the amphibian melanotrope cell. [VPAC1 receptor] (Mus musculus) PubMed
409.
findings document a critical role of VEGFR-3 in embryonic lymphatic development and function, and reveal a previously unrecognized modifier role of VEGF-D in the regulation of embryonic lymphangiogenesis in embryos (VEGF-D and VEGFR-3) (Mus musculus) PubMed
410.
RGM A and neogenin have important functions during early neural development. [neogenin] (Mus musculus) PubMed
411.
Tbx6 and mespb proteins interact physically with each other and regulate bowline expression. (mespb) (Mus musculus) PubMed
412.
These results suggest that GPR3 moderates the oocyte response to maturation-promoting signals, and that gonadotropin-mediated activation of metalloproteinases may play a partial role in sensitizing oocytes for maturation.[GPR3] (Mus musculus) PubMed
413.
Report elevation in heat shock protein 72 (HSP72) mRNA following contractions in isolated single skeletal muscle fibers. (Mus musculus) PubMed
414.
Gene expression of upstream stimulatory factors, USF1 and USF2, was first detected as maternal transcripts and was observed continuously throughout embryonic development (USF1 and USF2). (Mus musculus) PubMed
415.
ELYS chromatin capture recruits POM121 and NDC1 to initiate nuclear pore assembly (Mus musculus) PubMed
416.
Data demonstrate that the cell adhesion molecule of the neuronal immunoglobulin superfamily DM-GRASP/ALCAM/CD166 is required for normal heart development in X. laevis. [DM-GRASP] (Mus musculus) PubMed
417.
The accumulation of HSP110 in Xenopus laevis A6 kidney epithelial cells, was examined.[HSP110] (Mus musculus) PubMed
418.
Mix.1/2 regulates levels and/or duration of FGF signals to which pronephros precursors are exposed during gastrulation[mix1] (Mus musculus) PubMed
419.
p38 MAPK & CREB function along the dorsal-ventral axis in mesoderm patterning; the phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis & the p38 MAPK pathway mediates phosphorylation of CREB [p38 MAPK] (Mus musculus) PubMed
420.
Eg5 diffuses along individual microtubules without detectable directional bias at close to physiological ionic strength. Eg5's motility becomes directional when bound between two microtubules.[Eg5] (Mus musculus) PubMed
421.
matrix metalloproteinases 7, 9, and 18 are required in vivo for macrophage migration during embryonic development [MMP7] (Mus musculus) PubMed
422.
Dynein-dynactin transports the essential motor Eg5 toward the spindle poles in Xenopus laevis egg extract spindles, revealing a direct interplay between two motors of opposite directionality.[Eg5, dynein, dynactin] (Mus musculus) PubMed
423.
Data and preliminary model calculations suggest a faster turnover rate of PEPT1 in the presence of high substrate concentrations on the cytosolic surface [PEPT1]. (Mus musculus) PubMed
424.
XSeb4R interacts directly with the 3'-UTR of VegT mRNA, stabilizes it, and stimulates translation. (VegT) (Mus musculus) PubMed
425.
Left-sided heart-specific transcription of mouse galanin thus should be controlled by the left-right pathway[Galanin ] (Mus musculus) PubMed
426.
HURP and TPX2 have nonredundant functions essential for chromatin-induced microtubule assembly.[HURP] (Mus musculus) PubMed
427.
Data show that in Xenopus laevis oocytes, polar body emission requires a RhoA contractile ring and Cdc42-mediated membrane protrusion [RhoA]. (Mus musculus) PubMed
428.
Results suggest that Ryk functions as an essential regulator for noncanonical Wnt11/frizzled 7-mediated endocytosis in the regulation of Xenopus laevis convergent extension movements [ryk]. (Mus musculus) PubMed
429.
identify an essential role for Tgif1 in the control of nodal expression [ Tgif1 ] (Mus musculus) PubMed
430.
identify Rspo3 as a novel, evolutionarily conserved angiogenic factor in embryogenesis[ R-spondin 3] (Mus musculus) PubMed
431.
review mechanism of action and mode of regulation of Emi2, CSF function, and the general principles of APC/C regulation and control of protein function by MAPK pathways [review] [cytostatic factor, CSF] (Mus musculus) PubMed
432.
Data suggest that ADAM cleavage of cadherin-11 promotes migration by modifying its ability to support cell-cell adhesion while maintaining the membrane-bound pool of beta-catenin associated with the cadherin-11 cytoplasmic domain [cadherin-11]. (Mus musculus) PubMed
433.
Fgf8a induces NC indirectly through the activation of Wnt8 in the paraxial mesoderm, which in turn promotes neural crest (NC) formation in the overlying ectoderm primed by Bmp antagonists.[Fgf8a] (Mus musculus) PubMed
434.
These experiments reveal a conserved role for maternally-encoded Irf6 in differentiation of a simple epithelium in X. laevis and D. rerio.[Irf6] (Mus musculus) PubMed
435.
CaMKII turns on parallel pathways to activate the APC/C and to induce microtubule depolymerization at meiotic anaphase onset.[CamKII] (Mus musculus) PubMed
436.
SGK1 might participate in the regulation of insulin secretion in part by controlling Kv1.5 surface abundance.[Kv1.5] (Mus musculus) PubMed
437.
Data show that frg1 is expressed in and essential for the development of the tadpole musculature, and suggest that maintenance of normal FRG1 levels is critical for proper muscle development in frogs and humans [FRG1]. (Mus musculus) PubMed
438.
XCTK2 has a role in controlling spindle length by cross-linking and sliding microtubules. (Mus musculus) PubMed
439.
Results suggest that Rx-L, unlike Rx1, is required for the determination of retinal cell types, especially photoreceptors, rather than for proliferation of retinal progenitors [Rx-L]. (Mus musculus) PubMed
440.
Chemical inhibition of Wee1 and Myt1 or expression of Cdk1 phosphorylation site mutants allows reversal to M phase even from late G1[cyclin-dependent kinase 1] (Mus musculus) PubMed
441.
These results implicate MVP, and thus also vaults, in nuclear pore complexes (NPC)biogenesis.[MVP] (Mus musculus) PubMed
442.
Strong ERK activation can target Cdc25A for degradation in a manner similar to, but independent of, Chk1 for cell cycle arrest.[ERK1] (Mus musculus) PubMed
443.
Data show that Notch signaling acts downstream of foxD5 to promote the expression of a subset of neural ectodermal transcription factors; and Notch signaling and the foxD5 pathway maintain the neural plate in an undifferentiated state [foxD5]. (Mus musculus) PubMed
444.
N- and E-cadherin play primary roles in F-actin assembly in addition to roles in cell adhesion, and that this function is specific to individual cadherins[E-cadherin] (Mus musculus) PubMed
445.
These findings suggest that the MRN complex is a crucial mediator in the process whereby ATM promotes the TopBP1-dependent activation of ATR-ATRIP in response to double-stranded DNA breaks.[TopBP1] (Mus musculus) PubMed
446.
TopBP1 directly recruits the 9-1-1 complex to stalled DNA replication forks. (Mus musculus) PubMed
447.
The chromosomal distribution and dynamics of cohesin, the four-protein complex (RAD21/MCD1/SCC1, SMC1, SMC3, SCC3/SA2) responsible for sister chromatid cohesion, in Xenopus lampbrush chromosomes is characterized. RAD21, SMC1, SCC3. (Mus musculus) PubMed
448.
MAPK signaling specifically modulates coupling mediated by Cx50 and that gap junctional communication and signal transduction pathways may interact in osmotic regulation during postnatal fiber development.[Cx50] (Mus musculus) PubMed
449.
Data show that directionality and crosslinking are not the only characteristics for proper functioning of Kinesin-5 during spindle assembly in Xenopus egg extract; its motor domain properties are fine-tuned for its specific function [kinesin 5]. (Mus musculus) PubMed
450.
Isovaleric, methylmalonic, and propionic acids have anesthetic effects in tadpoles and modulate alpha1 glycine receptor function. (Mus musculus) PubMed
451.
FRG1 overexpression is capable of disrupting both the musculature and vasculature, recapitulating the two most prominent features of facioscapulohumeral muscular dystrophy.[FRG1] (Mus musculus) PubMed
452.
Data suggest that Shroom 1-4 proteins play an important role in the morphogenesis of several different epithelial tissues during development [shroom 1, 2, 3, 4]. (Mus musculus) PubMed
453.
These findings suggest a crucial role for the miR-430/427/302 family in vertebrate embryogenesis by controlling germ layer specification.[miR-427] (Mus musculus) PubMed
454.
These findings highlight a specific role for XMEF2C in tendon development and identify a novel gene transactivation pathway where MEF2C cooperates with the bHLH protein, Xscleraxis, to activate specific gene expression. (Mus musculus) PubMed
455.
The p24 proteins fulfil their role in secretory protein biosynthesis via COPI- or COPII-coated transport vesicles.[p24delta2] (Mus musculus) PubMed
456.
Lhx1 plays fundamental roles in blastoporal region since the ancestral eumetazoan arose, it contributed as an 'original organizer gene' to evolution of vertebrate gastrula organizer, and Lhx3 is involved in establishment of organizer gene networks. [lhx1] (Mus musculus) PubMed
457.
These results uncover new functions for TRAF4 as a Smurf1-regulated mediator of BMP and Nodal signaling that are essential for neural crest development and neural plate morphogenesis.[TRAF4, TGFB] (Mus musculus) PubMed
458.
Sex-typical vocalizations most likely arise from activation of different populations of 5-HT(2C) receptor expressing cells or from differential activation of downstream pattern generating neurons [5-HT2C receptor] (Mus musculus) PubMed
459.
CXCL14 expression in the ectoderm is regulated by both Bmp and canonical Wnt signaling[ CXCL14 ] (Mus musculus) PubMed
460.
The results suggest that FLRT3, Unc5B and Rnd1 proteins interact to modulate cell adhesion in early Xenopus development.[Rnd1] (Mus musculus) PubMed
461.
Results suggest that Xenopus MBD4/MLH1 participates in a novel G2 checkpoint that is responsive to DNMT1p levels in developing embryos and cells [Mbd4]. (Mus musculus) PubMed
462.
Data demonstrate that XProfilin2 and XProfilin1 are non-redundant effectors for Daam1 for non-canonical Wnt signaling and that they regulate distinct functions during vertebrate gastrulation [profilin1]. (Mus musculus) PubMed
463.
the cytoplasmic tail of Xcad-11 is both necessary and sufficient for proper cranial neural crest cell migration as long as it was linked to the plasma membrane[cad-11] (Mus musculus) PubMed
464.
SPLUNC1 is secreted onto mucosal surfaces as a soluble volume sensor whose concentration and dilution can regulate ENaC activity and mucosal volumes, including that of airway surface liquid.[SPLUNC1, ENaC] (Mus musculus) PubMed
465.
Report an adhesion-independent, aPKC-dependent function for E-cadherin in morphogenetic movements. (Mus musculus) PubMed
466.
Shroom2/spectrin/dynactin-based mechanism controls pigment localization in amphibian eggs and that variation in maternal Shroom2 mRNA levels accounts in part for variation in amphibian egg pigment patterns during evolution.[Shroom2] (Mus musculus) PubMed
467.
Dazap2 is a novel and essential branch of FGF-induced neural patterning.[Dazap2] (Mus musculus) PubMed
468.
Data suggest that both aPKC and Lgl2 affect cell fate, but that aPKC is a nuclear determinant itself that might shuttle from the membrane to the nucleus to control cell proliferation and fate [Lgl2, aPKC]. (Mus musculus) PubMed
469.
PIP(2) stimulates NBCe1-A activity, and phosphoinositides are regulators of bicarbonate transporters [NBCe1] (Mus musculus) PubMed
470.
Data show that Mind bomb (Mib), a ubiquitin ligase that promotes Notch ligand trafficking and activity, is a crucial molecular substrate for PAR-1 and is involved in neurogenesis [Mib, Par-1]. (Mus musculus) PubMed
471.
suggests that Mre11-Rad50-Nbs1 inactivation participates in the down-regulation of damage signaling during checkpoint recovery following double-strand breaks repair.[Mre11] (Mus musculus) PubMed
472.
These results demonstrate an essential role for Myo10 in normal cranial neural crest migration and suggest a link to cell-cell interactions and formation of processes [myosin 10]. (Mus musculus) PubMed
473.
Xiwi associates with translational regulators in an RNA-dependent manner, but Xenopus tudor interacts with Xiwi independently of RNA.[Piwi homologue] (Mus musculus) PubMed
474.
Results suggest that Frizzed 10 mediates Wnt1 signalling to determine sensory neural differentiation in Xenopus in vivo and in mouse cell culture [frizzled 10b]. (Mus musculus) PubMed
475.
Transport along actin filaments and the switching from actin to microtubule networks are regulated by changes in the diffusion time between periods of active motion driven by myosin-V. [myosin-V] (Mus musculus) PubMed
476.
analysis of CLIP-170-dependent capture of membrane organelles by microtubules initiates minus-end directed transport [CLIP170] (Mus musculus) PubMed
477.
work links the onset of zygotic gene expression in the Xenopus embryo with the translocation of Smicl from cytoplasm to nucleus, the phosphorylation of Rpb1 and the 3'-end processing of newly transcribed mRNAs.[Smicl and Rpb1] (Mus musculus) PubMed
478.
demonstrate that the maternal mRNAs for cyclins A1 and B2 each contain a single miR-427 target sequence, spanning less than 30 nucleotides, that is both necessary and sufficient for deadenylation.[miR-427] (Mus musculus) PubMed
479.
Position of Pro and Ser near Glu7.32 in the extracellular loop 3 is critical for the differential ligand selectivity between mammalian and nonmammalian GnRHRs. [GnRH-II] (Mus musculus) PubMed
480.
Membrane-proximal expression of the cytoplasmic domain of Ig alpha supports early B cell development as efficiently as the intact B cell receptor complex. [CD79A antigen (immunoglobulin-associated alpha), mb-1] (Mus musculus) PubMed
481.
Bves may play a role in cell adhesion and movement of epithelia during early embryogenesis [Bves] (Mus musculus) PubMed
482.
H2A histone family, member B3 (H2ABbd) confers lower stability to the nucleosome [H2ABbd] (Mus musculus) PubMed
483.
MURF-2 has roles in microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development [MURF-2, also called TRIM55 or RNF29] (Mus musculus) PubMed
484.
the complex of Nished, NFATc4, and co-activator p300 bound to the intronic regulatory element has a role in upregulating myosin light chain-2v in cardiac hypertrophy [NFATc4] (Mus musculus) PubMed
485.
Hoxd10 expression is sufficient to induce LS motoneuron identity and axon trajectories characteristic of motoneurons in the LS region [Hox10d] (Mus musculus) PubMed
486.
Alterations in mature SREBP-1 play role in mediating effects of starvation and feeding high-carbohydrate, low-fat diet on acetyl-CoA carboxylase-alpha transcription in chick liver. (Sterol regulatory element-binding protein-1) (Mus musculus) PubMed
487.
OCTN3 protein was mainly associated with the basolateral membrane of enterocytes [OCTN3] (Mus musculus) PubMed
488.
Sab is associated with the mitochondria and co-localizes with a portion of active JN kinase after stress treatment. (Sab--SH3BP5) (Mus musculus) PubMed
489.
RasGRP3 undergoes phosphorylation at Thr-133 upon B cell receptor cross-linking, thereby resulting in its activation (RasGRP3) (Mus musculus) PubMed
490.
Antigen receptor activation of wild type PKD is dependent on phospholipase C (PLC)/diacylglycerol (DAG) and PKC, whereas PKD-S744E/S748E is only dependent on PLC/DAG but no longer requires PKC [phospholipase C gamma 2] (Mus musculus) PubMed
491.
The chicken proglucagon gene is composed of seven exons, and contains an additional exon that contains much of intervening peptide 1 that has not been seen in any other proglucagon gene. (Mus musculus) PubMed
492.
effect of dietary protein intake and stage of development on chicken intestinal peptide transporter (cPepT1) mRNA abundance. (cPepT1) (Mus musculus) PubMed
493.
Activation of mGluR5 may modulate L-type voltage-gated Ca2+ current in these GABAergic amacrine cells via activation of protein kinase A, possibly via direct activation of a Ca2(+)-dependent adenylate cyclase. (mGlur5) (Mus musculus) PubMed
494.
Data suggest that Sox9 and Nkx2.5 are regulated independently by bone morphogenetic protein signaling, and act coordinately to specify the pyloric sphincter. (Mus musculus) PubMed
495.
activation and repression of FGFR1 gene transcription is governed by interplay between Sp1, p107, p130, and E2F4 in distinct transcriptional complexes during skeletal muscle development [FGFR1, E2F4, p107] (Mus musculus) PubMed
496.
The anterior region-specific expression of mario corresponds well with the presence of digit 2, and fate map analysis showed that mario expression at early stages represents the presumptive digit 2 region [mario] (Mus musculus) PubMed
497.
Agouti signaling (ASIP) genes exist in many species in lower vertebrates and were most probably present in early stages of vertebrate evolution. (agouti-signaling peptide; ASIP) (Mus musculus) PubMed
498.
Prx1a:Prx1b ratio and the alternative splicing mechanism that generates these two isoforms are critical in controlling chondrogenesis [Prx1a and Prx1b] (Mus musculus) PubMed
499.
Nrf3, adjacent to the Hox A cluster, is expressed during early development of the chicken embryo(NRF-3 protein) (Mus musculus) PubMed
500.
Interaction of steroid receptorss with chicken-transfected hsp90 is minimal when compared to a bona fide type of interaction, with the co-factors. (Mus musculus) PubMed
501.
in the neural retina, expression is restricted to the ventricular zone, where the cell bodies of retinal progenitor cells reside. (cRPTPlambda AND cRPTPpsi) (Mus musculus) PubMed
502.
a crucial role of Cdk5 in elongation and maintenance of axons as well as for stability and steering of their growth cones. (cdk35) (Mus musculus) PubMed
503.
Proneural proteins promote neurogenesis by upregulating Sox21. Key role for Sox21 in progression of neuronal differentiation. Important role of proneural proteins is capacity to upregulate Sox21. (Mus musculus) PubMed
504.
Results failed to demonstrate co-assembling of GATA factors or SCL with Lmo2. While overlapping expression of GATA-2/3 and SCL was detected, Lmo2 activation could not be demonstrated in neural cells in investigated period of neuronal development. (SCL) (Mus musculus) PubMed
505.
Cbfbeta and Runx1 display multiple combinatorial patterns in the endoderm and in specific nerves or ganglia.(Runx1) (Mus musculus) PubMed
506.
Results demonstrate a crucial role for NrCAM in the navigation of retinal ganglion cell axons in the developing retina towards the optic fissure, and also for pathfinding into the optic nerve [NrCAM]. (Mus musculus) PubMed
507.
PHI-1 may act as a CPI-17 analog in chicken smooth muscle and inhibit myosin phosphatase activity during G-protein stimulation to produce Ca2+ sensitization. (Mus musculus) PubMed
508.
This study show that distinct tissue competence to express Mkp3 rostrally and caudally to the zona limitans intrathalamica (ZLI). (Mus musculus) PubMed
509.
Commissural neurons from chicken embryos expressing a dominant-negative PlTPalpha mutant show reduced axon outgrowth. These results identify a crucial role for PlTPalpha in netrin-1-induced neurite outgrowth. [PITPalpha] (Mus musculus) PubMed
510.
talpid2 is likely to have a tissue-autonomous, bidirectional (positive and negative) role in hedgehog (HH) signaling [talpid2] (Mus musculus) PubMed
511.
isolation and molecular characterization of the chick ortholog of nyctalopin (NYX), the gene responsible for X-linked complete congenital stationary night blindness (Mus musculus) PubMed
512.
Sema5A is expressed in the newly formed atrioventricular valves in the embryonic heart [Sema5A] (Mus musculus) PubMed
513.
findings revealed that phospho-CREB is specifically expressed in a previously unreported myelin-associated protein of oligodendrocytes[CREB] (Mus musculus) PubMed
514.
AWAK. Chick intestine contains a novel 767 amino acid avian protein which has a proposed molecular weight of 81kDa. The presence of WAP and Kunitz modules suggests that AWAK has proteinase inhibitor activity. (Mus musculus) PubMed
515.
ALG-2. The interaction of the ALG-2/Alix complex with TSG101 and CHMP4b is necessary for naturally occurring death of motoneurons. (Mus musculus) PubMed
Neuropeptide Y content in chick embryo hypothalamus during development. (Mus musculus) PubMed
518.
The reciprocal expression of heat shock transcription factor 1 (HSF1) and heat shock transcription factor 3 (HSF3) in blood and brain in response to heat exposure is reported. [HSF1; HSF3] (Mus musculus) PubMed
519.
Muscularization of cushion-derived mesenchymal tissues in embryonic heart is associated with a discrete genetic program reflected by the expression of h1-calponin. [h1-calponin] (Mus musculus) PubMed
520.
redistribution of PS is dependent on an increase in phospholipid scramblase activity and a decrease in APLT activity.Lastly,we show that translocator activity is likely to be modulated by membrane cholesterol levels through a membrane raft microdomain (Mus musculus) PubMed
521.
The presence of MMP-9 enzyme was negatively correlated with the presence of TIMP-1 enzyme [TIMP-1] (Mus musculus) PubMed
522.
Shh contributes to CDC25B transcriptional activation in the neural tube both of chick and mouse embryos (CDC25B) (Mus musculus) PubMed
523.
The acquisition of DNA (cytosine-5-)-methyltransferase 3-like(DNMT3L) by a common ancestor of eutherians and marsupials might have been closely related to the evolution of imprinting. (DNMT3L) (Mus musculus) PubMed
524.
Several proteins associated with the egg shell membranes (ESM) with antibacterial activity have been identified including beta-N-acetylglucosaminidase (beta-NAGase)and pure fractions of beta-NAGase were obtained from egg white. [beta-NAGase] (Mus musculus) PubMed
525.
biochemical behavior of di-N-acetylchitobiase indicates it has three subsites, -2, -1, +1, in which the reducing-end trimer of any sized chitooligosaccharide is bound. The +1 site is specific for an alpha-anomer [di-N-acetylchitobiase] (Mus musculus) PubMed
526.
TSK isoforms play a crucial role in chick axis formation by locally modulating VG1 and BMP activities during gastrulation.(VG1) (Mus musculus) PubMed
527.
May be involved in regulating the development and functional maturation of the pineal gland. (Islet-1) (Mus musculus) PubMed
528.
isolated a homologue of BM88, a cell-intrinsic nervous system-specific protein and examined the expression of BM88 mRNA and protein in the developing nervous system of the embryo by in situ hybridization and immunohistochemistry (BM88) (Mus musculus) PubMed
529.
The expression of the chick four-jointed (fjx) homologue during embryonic development was determined. (Mus musculus) PubMed
530.
Our data indicate that Muller cells in the chicken retina possess 11-cis-ARAT activity, thus providing an explanation for the accumulation of 11-cis-retinyl esters in the cone cycle[11-cis acyl-CoA:retinol O-acyltransferase] (Mus musculus) PubMed
531.
Data show that Notch2, Hey1 and Hey2 initiate a signaling cascade that delimits the non-chamber atrioventricular canal (AVC) and inner curvature (IC) regions of the developing heart [Hey1, Hey2] (Mus musculus) PubMed
532.
PHI-1 inhibits myosin light chain phosphatase by interacting with the active site of PP1c to produce a Ca(2+) independent increase in myosin light chain(20) phosphorylation and force[PHI-1, myosin light chain(20) and myosin light chain phosphatase] (Mus musculus) PubMed
533.
investigated the domain requirements and transcriptional activities associated with Dlx5- and Dlx6-mediated chondrogenesis[Dlx6] (Mus musculus) PubMed
534.
fibroblast growth factor (FGF), FGF8-soaked beads induce ectopic mkp3 expression, indicating that apical ectodermal ridge apical ectodermal ridge-derived FGF8 protein may activate mkp3 in the distal mesenchyme[mkp3] (Mus musculus) PubMed
535.
Results describe the gene expressions of taurine transporter and taurine biosynthetic enzyme during mouse and chicken embryonic development [taurine transporter]. (Mus musculus) PubMed
536.
in addition to thecal perlecan, ggBM1 is involved in the transfer of yolk precursors from the thecal capillary bed to oocyte surface lipoprotein receptors mediating their uptake into oocytes [ggBM1] (Mus musculus) PubMed
537.
The present findings show that the interaction between PKCgamma and GluR4 is specifically required to assure PKC-driven phosphorylation and surface membrane expression of GluR4.[PKCgamma] (Mus musculus) PubMed
538.
These findings collectively show for the first time that multiple MMPs, ADAMs, and TIMPs appear to functionally interact during corneal development.[TIMP1] (Mus musculus) PubMed
539.
These results suggested that lysophosphatidic acid in hen egg white is produced from lysophospholipids, especially LPC, by the action of ATX/lysoPLD, possibly originating from hen oviduct fluid.[Lysophospholipase D] (Mus musculus) PubMed
540.
CYP1B1 is one of the RALDH-independent components by which embryos direct Retinoic Acid-mediated patterning. [CYP1B1] (Mus musculus) PubMed
541.
function of miR-124 during spinal cord development; miR-124 appears to ensure that progenitor genes are post-transcriptionally inhibited in neurons [miR-124] (Mus musculus) PubMed
542.
Reelin-expressing primary retinal cultures were used to investigate the role of the four Dab1 tyrosine phosphorylation sites on overall tyrosine phosphorylation, Dab1 phosphorylation, Src family kinase activation and neurite formation.[Dab-1] (Mus musculus) PubMed
543.
The ability of supplementation of Freund adjuvant to enhance the quantity of specific immunoglobulin Y in eggs of laying hens. [immunoglobulin Y IgY] (Mus musculus) PubMed
544.
alpha-MSH causes behavioral effects that may secondarily affect feed intake at a low magnitude and may modulate the behavioral effects of NPY in chicks, contributing to the overall effect on feed intake [alpha-MSH] (Mus musculus) PubMed
545.
analysis of expression patterns of chick Musashi-1 in the developing nervous system [Musashi-1] (Mus musculus) PubMed
546.
specific H1R variant plays a unique and important role in the DNA damage response in vertebrates. (Mus musculus) PubMed
547.
Data show that on binding of Slit to Robo, the adaptor protein Cables is recruited to Robo-associated Abl and forms a multimeric complex by binding directly to N-cadherin-associated beta-catenin [Robo, Cables]. (Mus musculus) PubMed
548.
fesselin is a natively unfolded protein [fesselin] (Mus musculus) PubMed
549.
cHS4 insulator counteracts telomeric position effects in an upstream stimulatory factor-independent manner [cHS4] (Mus musculus) PubMed
550.
Intracerebroventricular neuropeptide S causes anorexigenic effects in chicks, without directly affecting water intake, and the hypothalamus is involved. (Mus musculus) PubMed
551.
Retinal dehydrogenase 1 (RALDH1) mRNA levels in the chick duodenum increased during the postnatal period, indicating a similar developmental expression pattern to that of BCMO1. (Mus musculus) PubMed
552.
These studies on the biochemical characterization of the recombinant proteins suggest the interdependence of the two domains for proper organization of the riboflavin binding pocket.[Riboflavin carrier protein] (Mus musculus) PubMed
553.
ZBP2, a homologue of the splicing factor KSRP, binds initially to nascent beta-actin transcripts and facilitates the subsequent binding of the shuttling ZBP1.[ZBP1, ZBP2] (Mus musculus) PubMed
554.
This study found that tissue hypoxia is likely a normal component of embryonic development in the chicken based on the upregulation of hypoxia response genes, including hypoxia upregulated protein 1(HUP1).[HUP1] (Mus musculus) PubMed
555.
PTPsigma can thus show differential complex formation with different Trk family members and in neurons can selectively target the neurite-forming signalling pathway driven by TrkA.[PTPsigma] (Mus musculus) PubMed
556.
a novel role for Cad6B in controlling the proper timing of neural crest emigration and delamination from the neural tube of the avian embryo. (Mus musculus) PubMed
557.
A 2.0 A resolution crystal structure of myristoylated GCAP1 with Ca(2+) bound (GCAP1). (Mus musculus) PubMed
558.
Thyroid receptor beta 0 (TRbeta0) trimers have DNA recognition and transcriptional regulatory properties that are not observed for dimers. (Mus musculus) PubMed
559.
The vertebrate KNL1 counterpart is essential for chromosome segregation and is required to localize a subset of outer kinetochore proteins.[KNL1] (Mus musculus) PubMed
560.
Sema6A acts as a gate keeper between the PNS and the CNS both ventrally and dorsally. (SEMA6A, CHICKEN) (Mus musculus) PubMed
561.
These findings demonstrate, for the first time, the contribution of Isl1(+) splanchnic mesoderm cells to a subset of branchiomeric skeletal muscles.[Islet-1] (Mus musculus) PubMed
562.
partial cloning, characterization and tissue distribution of chicken 11beta-hydroxysteroid dehydrogenase type 2. (Mus musculus) PubMed
563.
closely related adhesion molecules--Dscam, DscamL, Sidekick-1 and Sidekick-2--are expressed in chick by non-overlapping subsets of interneurons and RGCs that form synapses in distinct IPL sublaminae [DscamL] (Mus musculus) PubMed
564.
The regulation of S6K1 differs between the liver and muscle and between chickens divergently selected for growth. There is a potential involvement of S6K1 in the control of muscle growth and an open issue concerning S6K1 function in chicken liver [S6K1] (Mus musculus) PubMed
565.
helical and kinase domain mutations act synergistically when present in the same p110alpha molecule[p110alpha of phosphatidylinositol 3-kinase] (Mus musculus) PubMed
566.
Cdk6 up-regulation in TDP-43-depleted cells is accompanied by an increase in phosphorylation of two of its major targets, the retinoblastoma protein pRb and pRb-related protein pRb2/p130. TDP-43] (Mus musculus) PubMed
567.
Par6/Smurf1/RhoA have roles in regulating EMT in endocardial cells (Mus musculus) PubMed
568.
A key role for phospholipase C-gamma2 (PLCgamma2), Vav, B cell linker, and Bruton's tyrosine kinase in the formation of highly coordinated "microsignalosomes," , is identified.[Plcgamma2] (Mus musculus) PubMed
569.
A report on the isolation and expression pattern of the Sizzled gene in the chick embryo (Sizzled). (Mus musculus) PubMed
570.
In the embryonic heart, JNK activity exhibits a characteristic pattern during anoxia and reoxygenation and the respective open-state of ion channels can be a major determinant of JNK activity.[mtioKATP, JNK] (Mus musculus) PubMed
571.
HC progenitors are sensitive to follistatin and become committed to produce Lim1+ HC subtypes concomitantly with or early after their own generation [Lim1] (Mus musculus) PubMed
572.
findings are consistent with mGluR1 activating inositol (1,4,5)-trisphosphate receptors to release intracellular Ca(2+) required for long-term memory formation and have been interpreted within a long term potentiation 2 model[MGLUR1] (Mus musculus) PubMed
573.
TGF-beta1, TGF-beta2, TGF-beta3 have different roles in the embryonic nervous system of mouse and chicken [TGF-beta1] (Mus musculus) PubMed
574.
results provide evidence for the important role of vasotocin receptor VT2 in mediating effects of arginine vasotocin on endocrine secretion from corticotropes and, partially, from lactotropes [VT2R] (Mus musculus) PubMed
575.
misexpression of the EWS-FLI1 oncogene in neural crest-derived stem cells may be an initiating event in ESFT genesis.(EWS-FLI1) (Mus musculus) PubMed
576.
DNA binding and functional assays revealed that the 5'-UTR has a consensus neuron-restrictive silencing element that binds NRSF, and a SP element that binds SP3, both repressing Grin1 transcription in undifferentiated P19 cells and PC12 cells. [NRSF] (Mus musculus) PubMed
577.
Results show that the serine/threonine kinase death-associated protein kinase (DAPK) is involved in the signal transduction of neogenin [DAP kinase]. (Mus musculus) PubMed
578.
Data show that SynCAM is expressed in the chick ciliary ganglion, embedded in a nicotinic pathway, and, as shown previously for neuroligin and L1-CAM, acts transcellularly to promote synaptic maturation on the neurons in culture [synCAM]. (Mus musculus) PubMed
579.
Results provide evidence for 11beta-hydroxysteroid dehydrogenase type 1 as a tissue-specific regulator of glucocorticoid action in non-mammalian vertebrates [11HSD1]. (Mus musculus) PubMed
580.
The 1.8-A-resolution crystal structure of the CHIR-AB1 ectodomain, is described.[CHIR-AB1] (Mus musculus) PubMed
581.
Gonadotrophin-inhibitory hormone receptor (GnIHR) expressed in FSHbeta or LHbeta mRNA-containing cells is likely to mediate the inhibitory effect of GnIH on LH and FSH secretion.[Gonadotrophin-inhibitory hormone receptor] (Mus musculus) PubMed
582.
Short time exposure to hypoxia increases DNA synthesis in primary cultured chicken hepatocytes through cooperation of Ca2+/PKC, p38 MAPK, p44/42 MAPKs, and PI3K/Akt pathways.[mTOR protein] (Mus musculus) PubMed
583.
NP25 plays a dynamic role in the regulation of neurite growth. (Mus musculus) PubMed
584.
Data show that Art7.1 was predominantly expressed on the surface of B cells from the bursa of Fabricius as a GPI-anchored form, as well as on T cells from the thymocytes [Art7.1]. (Mus musculus) PubMed
585.
Expression of full-length human NMHC-IIA and -IIB in 10 T1/2 cells demonstrated that flectin antibody recognizes both isoforms (Mus musculus) PubMed
586.
ENOX2 may fulfill some functions essential to the growth of early embryos which are lost in late embryo stages and absent from normal adult cells but which then reappear in cancer. (Mus musculus) PubMed
587.
FKBP65 is also able to interact with triple helical collagen, and acts as a collagen chaperone[ FKBP65 ] (Mus musculus) PubMed
588.
local structural changes in the protein due to cation binding or ligand binding (protonation)[acid sensing ion channel-1] (Mus musculus) PubMed
589.
In skeletal muscle, fesselin was associated with desmin in regularly spaced bands distributed along the length of muscle fibers suggesting localization to the Z-line. [fesselin] (Mus musculus) PubMed
590.
Study determined the crystal structure of CG-1B; position of the Trp ring in the lectin site, presence of only 2 ordered water molecules therein, and changes in interface region between the 2 subunits, set the structure of CG-1B apart from CG-1A.[CG-1B] (Mus musculus) PubMed
591.
These findings indicate that the CAV promoter activity can be affected directly or indirectly by COUP-TF1 and deltaEF1. [COUP-TF1] (Mus musculus) PubMed
592.
These results suggest that neurogenin 3 (ngn3) regulates retinal neurogenesis by inducing regulatory genes for early-born neurons and repressing those for later-born cells [ngn3]. (Mus musculus) PubMed
593.
IL-6 stimulates the proliferation of primary cultured chicken hepatocytes through PKC, p44/42 MAPKs, and PPARdelta pathways.[PPARdelta, Mapk3] (Mus musculus) PubMed
594.
The Fcupsilon3-4 structure reveals features common to both IgE-Fc and IgG-Fc, and the implications for IgY binding to its receptor are discussed.[IgY] (Mus musculus) PubMed
595.
TGF-beta1 inhibits skeletal muscle growth by regulating MyoD and myogenin expression [transforming growth factor-beta1] (Mus musculus) PubMed
596.
The expression pattern of IP(3)R contributes to the formation of specialized calcium release-activated calcium current stores in B cells.[IP3 receptor] (Mus musculus) PubMed
597.
These studies suggest that portions of the KV4.2 T1 domain can act as docking sites for proteins such as PPTX, further underscoring the significance of this domain.(KV4.2 protein, chicken) (Mus musculus) PubMed
598.
Patch-clamp photometry was used to determine the contribution of Ca(2+) to total current through native and recombinant ASIC1a receptors.[ASIC1a] (Mus musculus) PubMed
599.
Cyclic mechanical stretch increased cardiomyocyte (CM), but not non-CM, proliferation and increased p38MAPK phosphorylation.[p38MAPK] (Mus musculus) PubMed
600.
These findings reveal that retinoid and Sema6A/PlexA4 signaling pathways intersect through FARP1 to control dendritic growth(Farp1 protein, chicken) (Mus musculus) PubMed
601.
The normal FOP protein localizes at the centrosome throughout the cell cycle and preferentially accumulates at the distal end of the mother centriole.[FOP] (Mus musculus) PubMed
602.
At the calyciform synapse, rapid synaptic transmission is mediated apparently without participation of ionotropic receptors concentrated at postsynaptic densities.[alpha3-nAChR, alpha7-nAChR] (Mus musculus) PubMed
603.
The complex of YF1*7.1 heavy chain and beta(2)-microglobulin was reconstituted and purified without a peptide.[YF1*7.1] (Mus musculus) PubMed
604.
Expression of arginine vasotocin receptor 2 (VT2R) in the pituitary was increased in chickens with 2-thiouracil-induced hypothyroidism; expression of VT2R in the pituitary was decreased by water deprivation of such birds [VT2R] (Mus musculus) PubMed
605.
results indicate that myostatin and peroxisome-proliferator-activator-gamma-coactivator-1alpha(PGC-1alpha) expression in the skeletal muscle rapidly change in response to acute cold(PGC-1alpha) (Mus musculus) PubMed
606.
Although the complete helicase domain is critical for crosslink repair, a predicted inactivating mutation of the Walker B box domain has no impact on Fanconi Anaemia pathway associated functions (FANCM). (Mus musculus) PubMed
607.
Akt activity can regulate growth cone expansion via localized Rac1 signaling and regulate axonal branching and soma size via activation of mTOR. (Mus musculus) PubMed
The expression of this gene varied from tissue to tissue. The study with labelled green fluorescence showed that the protein mainly concentrated in the nucleus. (Mus musculus) PubMed
610.
These data suggested that the apoptotic effect of transforming growth factor-beta1 on satellite cells is likely associated with a beta1 integrin-mediated focal adhesion kinase signaling pathway.[beta1 integrin] (Mus musculus) PubMed
611.
Results identified a centromere protein S (CENP-S)-containing subcomplex that includes the new constitutive kinetochore protein CENP-X [CENP-X, -S]. (Mus musculus) PubMed
612.
Epigenetic mechanisms are necessary for in vivo chicken alpha-globin gene switching through differential gene silencing of the embryonic alpha-globin gene in order to allow proper activation of adult alpha-globin genes.[Pi globin] (Mus musculus) PubMed
613.
3BP2 induces the protein complex with cellular signaling molecules through phosphorylation of Tyr(183) and SH2 domain leading to the activation of NFAT in B cells [3BP2] (Mus musculus) PubMed
614.
The effect of dietary phenylalanine on the activity of phenylalanine-pyruvate aminotransferase (PAT) activity in broiler chicks is reported.[PAT] (Mus musculus) PubMed
615.
A study evaluating the tissue distribution and relationship to aging of xanthine oxidoreductase (XOR) in broiler chicks is reported.[XOR] (Mus musculus) PubMed
616.
The novel gene, OSU-T1-50 displayed a very dynamic enhancement of gene expression during trophoblastic elongation. It may play an important role in trophoblastic elongation[OSU-T1-50] (Mus musculus) PubMed
617.
LLC-PK1 cells transport L-leucine through Na+-independent pH-insensitive and high-affinity LAT1 transporter and L-DOPA through Na+-independent pH-insensitive and low-affinity LAT2 transporter. (LAT1, LAT2) (Mus musculus) PubMed
618.
the p38 MAPK is an upstream component of Akt-mediated eNOS activation [p38 MAPK; Akt kinase] (Mus musculus) PubMed
619.
identified a secretolytin-like peptide (KR-11, pCgB(637-647)) from porcine chromaffin granules[KR-11 peptide] (Mus musculus) PubMed
620.
Data suggest that force suppression is mediated by phosphorylation of heat shock protein 20, resulting full or partial inhibition of local myosin binding at the thin- or thick-filament level. (Mus musculus) PubMed
621.
is involved in the meiotic maturation of mammalian oocytes, and blocking Cdk2 activity results in the failure of cyclin B1 accumulation and second meiosis induction (Mus musculus) PubMed
622.
results suggest that the N-glycans located in the N-terminal half of the zona pellucida domain of porcine zona pellucida B glycoprotein(ZPB) are involved in sperm-zona binding (Mus musculus) PubMed
623.
Piglets infected with E coli O55 showed a significant increase of plasma calprotectin and the highest mean level of calprotectin in the bronchoalveolar lavage, which was coincident with septicaemia [calprotectin] (Mus musculus) PubMed
624.
Knockout of this enzyme in pigs makes it possible to transcend barriers for heart transplantation (alpha1,3-galactosyltransfesrase) (Mus musculus) PubMed
625.
Chemokines acting via CXCR2 and platelet-activating factor are released by porcine endothelial cells inducing efficient chemotaxis of human neutrophils. (CXR2, platelet activating factor) (Mus musculus) PubMed
626.
Data suggest that polarized, shear stress-induced signaling from focal adhesions at the upstream lamellae,leads to the local inactivation of Rac1 by inhibiting paxillin and p130CAS phosphorylation [paxillin, p130CAS, Rac1]. (Mus musculus) PubMed
627.
Genetic variability is assocated with reproductive traits. (ESR genes) (Mus musculus) PubMed
628.
Enzyme-mediated cardioprotection after ischemia-reperfusion involves, at least in part, the phosphatidylinositol 3-kinase/AKT pathway [AKT] (Mus musculus) PubMed
629.
The number of calretinin and reelin-positive neurons decreased from 1 day to one year. (Reelin and calretinin) (Mus musculus) PubMed
630.
developmental change in PKB activation is isoform specific and involves regulation by PDK-1 [PDK-1, PKBalpha, PKBbeta] (Mus musculus) PubMed
631.
hypoxia induces overexpression of alphaB crystallin in the gastrointestinal tract of the newborn piglet [alphaB crystallin] (Mus musculus) PubMed
632.
Nuclear Mitotic Apparatus (NuMA) protein is contributed by the donor cell nucleus in cloned porcine embryos [NuMA] (Mus musculus) PubMed
633.
These data indicate that Ang-(1-7) inhibits the proximal tubule Na+-ATPase by interaction with the AT2 receptor that subsequently activates the G(i/o) protein/cGMP/PKG pathway.[Na AtPase] (Mus musculus) PubMed
634.
Activation of Rac1 and inhibition of RhoA restored the abnormal phenotype and permeability of hypertensive pulmonary artery endothelial cells to normal. (Rac1 AND RhoA) (Mus musculus) PubMed
635.
Upregulation mechanisms underlying the B1 receptor takes place in an ocular tissue, the pig iris sphincter. (bradykinin b1 receptor) (Mus musculus) PubMed
636.
existence of Amylo-1,6-glucosidase as well as glycogen phosphorylase in the brain explains brain glycogenolysis fully and supports the hypothesis that glycogen is a significant source of energy in this organ [Amylo-1,6-glucosidase ] (Mus musculus) PubMed
637.
genomic structure and a novel alternatively spliced forms [pre-T cell receptor alpha] (Mus musculus) PubMed
638.
results suggest that the proteolysis of securin is dependent on ubiquitin-proteasome pathway and is necessary for the degradation of Rec8 during meiotic metaphase-to-anaphase transitions in oocytes [securin, Rec8] (Mus musculus) PubMed
639.
evidence that neonatal uterine expression of LGR7 & LGR8 is detectable at birth, is regulated developmentally during an established critical period for estrogen-sensitive uterine programming & is stimulated by estrogen exposure [LGR7,LGR8] (Mus musculus) PubMed
640.
glycolysis starts at concrete points in the boar-sperm surface[ADP-dependence of pyruvate kinase] (Mus musculus) PubMed
641.
signaling by RA via RA receptors regulates the expression of NRL, providing a framework for delineating early steps in photoreceptor cell fate determination [photoreceptor transcription factor NRL] (Mus musculus) PubMed
642.
results implicate TNFalpha and TNFalpha-RII as important actors in both the acute and the chronic phases of inflammation following stent implantation [TNFalpha receptor II] (Mus musculus) PubMed
643.
A study of the mapping characteristics and relationship to body composition of FAT1 and FABP4 in swine is reported.[FAT1] (Mus musculus) PubMed
644.
electrons from the electron transfer flavoprotein(ETF) flavin semiquinone may enter the ETF-ubiquinone oxidoreductase flavin one by one, followed by rapid equilibration with the cluster[Electron transfer flavoprotein-ubiquinone oxidoreductase] (Mus musculus) PubMed
645.
CD4(-) gammadelta thymocytes that can be further subdivided according to their CD2/CD8alphaalpha phenotype[TCRgammadelta] (Mus musculus) PubMed
646.
the presence of the halothane gene induced early energy depletion, which could be a primary reason causing AMPK activation, leading to accelerated glycolysis and an increased incidence of PSE meat [AMPK & Porcine Stress Syndrome gene] (Mus musculus) PubMed
647.
These results suggest that lysoPAF was degraded by high ecto-lysophospholipase C activity.[Lysophospholipase C] (Mus musculus) PubMed
648.
Perturbing the amount of Smarca 2 in porcine embryos disrupts cleavage development. (Mus musculus) PubMed
649.
Hepatocyte nuclear factor 4 alpha (HNF-4 alpha)induces apoliprotein IV gene in response to dietary lipids in the intestine. (Mus musculus) PubMed
650.
The MUC4 g.243A>G mutation is strongly associated with susceptibility to enterotoxigenic Escherichia coli F4ab/ac infection. (Mus musculus) PubMed
651.
New role for PBR which could be a major target in the regeneration process during ischemia reperfusion. (PBR, peripheral-type benzodiazepine receptor) (Mus musculus) PubMed
652.
This study suggested closer links between the release of haptoglobin, Pig-MAP and monocytes compared to the release of AGP, serum amyloid A and transthyretin.[Pig-MAP; serum amyloid A] (Mus musculus) PubMed
653.
the phosphorylation pattern and activity of the kinase p90rsk,during in vitro and in vivo maturation of pig oocytes. (Mus musculus) PubMed
654.
Platelet derived growth factor A and B (PDGF-A/PDGF-B) were up-regulated in model of obliterative bronchiolitis. (Mus musculus) PubMed
655.
Arylesterase distribution in minipig skin in similar to that in human skin. (Mus musculus) PubMed
656.
Demonstrate the presence of a human lactoferrin receptor homologue in pig, with mRNA and protein expression concomitantly regulated in the duodenum and inversely regulated in the jejunum. (Mus musculus) PubMed
657.
Blockade of the thromboxane A2/prostaglandin H2 receptor provided a fast and potent platelet inhibitory effect in a porcine model of in-stent thrombosis. (Mus musculus) PubMed
658.
the N(pro) protein targets interferon regulatory factor-3 (IRF-3) for degradation by proteasomes and thus prevents IRF-3 from activating transcription from the IFN-beta promoter. (Mus musculus) PubMed
659.
Beneficial effect of nicorandil on endothelial junctions could be due to its effect on endothelin-1 (ET-1) via the activation of KATp channel. (Mus musculus) PubMed
660.
mitocryptide-2 (MCT-2) and its human homolog hMCT-2 are cryptides that activate neutrophils[Mitocryptide-2] (Mus musculus) PubMed
661.
Results discuss how constitutively bound factors such as NF1 and Oct1 may participate in the maintenance of tissue specificity of genes responsive to hormones through receptors such as the glucocorticoid receptor. [Nf1] (Mus musculus) PubMed
662.
Hsp70 expression in the thoraces of flight-capable bees is probably flight-induced by oxidative and mechanical damage to flight muscle proteins rather than temperature.[HSP70] (Mus musculus) PubMed
663.
Strains with mutations in either the prcA-prtP or the msp region showed altered expression of the other locus. (msp = major outer sheath protein) (Mus musculus) PubMed
664.
The gene encoding the Treponema denticola factor H-like protein 1 (FHL-1) binding protein, FhbB, was recovered and characterized [FhbB] (Mus musculus) PubMed
665.
Msp inhibits the polarized accumulation of activated Rac and PI3-kinase products upon exposure to formyl-methionyl-leucyl-phenylalanine (fMLP). [major outer sheath protein (Msp)] (Mus musculus) PubMed
666.
These data suggest that major outer sheath protein (MSP) acts as an adhesin during the coaggregation process of T. denticola with P. gingivalis and F. nucleatum through its protein and carbohydrate moieties, respectively. [MSP] (Mus musculus) PubMed
667.
In this study we demonstrated with a pull-down assay that purified full-length recombinant lipoprotein FhbB (lacking the leader peptide) binds exclusively to FH and not to FHL-1(factor H-like protein 1). [FhbB] (Mus musculus) PubMed
668.
Results of our studies suggest that the C. jejuni NeuNAc synthase catalyses the condensation of the si face of PEP with the aldehyde sugar. [neuB1] (Mus musculus) PubMed
669.
A Campylobacter jejuni two-component signal transduction system, designated dccR-dccS (diminished capacity to colonize; Cj1223c-Cj1222c), has been found to be important for in vivo colonization but dispensable for in vitro growth [dccR;dccS strain 81-176] (Mus musculus) PubMed
670.
alternative model of evolution for FbpA homologs involving an early iron-binding ancestor instead of a requirement for a preexisting anion-binding ancestor. (ferric binding protein) (Mus musculus) PubMed
671.
identification and characterization of a new DsbB-related disulfide oxidoreductase (DsbI) from C. jejuni [DsbI] (Mus musculus) PubMed
672.
findings show the profound effect of a resistance-conferring point mutation in gyrA on the fitness of a foodborne pathogen in its natural host & suggest a reason for the rapid emergence of FQ-resistant Campylobacter on a worldwide scale [gyrA, strain S3B] (Mus musculus) PubMed
673.
The frequence, chromosomal distribution and localization of tet(O) on plasmid and chromosomal DNA of C. jejuni strains isolated in Australia is reported. [tet(O) gene] (Mus musculus) PubMed
674.
cloning, sequence analysis and expression of OXA-61, a novel molecular class D beta-lactamase [OXA-61] (Mus musculus) PubMed
675.
Phenylalanine-arginine-leucine-serine residues (CadF AA 134-137) of the C. jejuni CadF protein possess fibronectin-binding activity. (Mus musculus) PubMed
676.
DprA ortholog that functionally most closely resembles that of H. pylori and is involved in DNA transformation [DprA] (Mus musculus) PubMed
677.
In this study, an unusual phase-variable mechanism controlling production of FlgR, the response regulator of the FlgSR two-component system required for transcription of sigma54-dependent flagellar genes, is identified. (Mus musculus) PubMed
678.
the Cj0618 gene deletion mutant showed a caecal colonization defect in chick infection.[Cj0618] (Mus musculus) PubMed
679.
The data suggest that DocA and Cjj0382 have characteristics of CCPs but likely perform different physiological functions for the bacterium in colonization that are not related to resisting oxidative stress. [docA and Cjj0382] (Mus musculus) PubMed
680.
Data suggest that the FlgR receiver domain has the capacity for regulation in controlling the activation of the protein and FlgR lacks a DNA-binding motif and is not required for sigma(54)-dependent flagellar gene expression [FlgR] (Mus musculus) PubMed
681.
CprRS influences expression of factors important for biofilm formation, colonization and stress tolerance. [CprR; CprS] (Mus musculus) PubMed
682.
By using genetic approaches, we found that FlgSR activity is linked to and downstream of the flagellar export apparatus in a regulatory cascade that terminates in expression of sigma(54)-dependent flagellar genes.[FlgS & FlgR] (Mus musculus) PubMed
683.
In summary, mutation of cj0596 alters the Campylobacter jejuni OMP profile and leads to changes in OMP-related phenotypes involved in Campylobacter jejuni pathogenesis.[cj0596 homolog] (Mus musculus) PubMed
684.
The three-dimensional structure of H. pylori ACP and its structural characteristics were clarified using NMR and CD spectroscopy [Acyl carrier protein] (Mus musculus) PubMed
685.
crystal structure of Spermidine Synthase [Spermidine Synthase] (Mus musculus) PubMed
686.
interaction of HSP60 with TLR (toll-like receptors)in gastric epithelial cells contributes to development of gastic inflammation of H. pylori infection. [HSP60] (Mus musculus) PubMed
687.
results demonstrate that periplasmic carbonic anhydrase is essential for survival of H. pylori in an acid environment studied in vitro [alpha-CA strain ATCC43504] (Mus musculus) PubMed
688.
interacts with fibronectin and alters HeLa cell adhesion and cytoskeletal organization in vitro [VacA] (Mus musculus) PubMed
689.
The vacuolating activity of VacA is due mainly to the free-soluble form rather than the outer membrane vesicle-associated form of VacA. (Mus musculus) PubMed
690.
Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori [Hp-QAPRTase] (Mus musculus) PubMed
691.
role of DsbI protein in Helicobacter pylori pathogenesis; demonstrated that a dsbI mutant impaired in disulfide bond formation revealed a greatly reduced ability to colonize mice gastric mucosa [DsbI] (Mus musculus) PubMed
692.
The recombinant KatA has original antigenicity. [KatA] (Mus musculus) PubMed
693.
Altogether, Ni-free and Ni-bound structures have allowed determination of the route for nickel within HpNikR and reveal the cooperativity between the tetramerization domain and the DNA-binding domain. [NikR protein] (Mus musculus) PubMed
694.
We identify the gene hp0421 as encoding the enzyme cholesterol-alpha-glucosyltransferase responsible for cholesterol glucosylation [hp0421] (Mus musculus) PubMed
695.
we analyzed the amino acid sequence of HrcA that predicted association of this protein to the inner membrane, which was experimentally verified. The functionality of the purified protein was then confirmed with an in vitro DNA-binding assay.[HrcA] (Mus musculus) PubMed
696.
The prevalence of cytotoxin-associated gene A positivity was significantly higher in Behcet's disease compared to the controls [cagA] (Mus musculus) PubMed
697.
hp0015 is associated with adhesion, and hp0015, hp0016, and hp0017 are associated with natural transformation. Hp0017 has been named as virB4/comB4. Therefore, hp0015 and hp0016 are named as comB2 and comB3, respectively.[virB4, comB2, comB3] (Mus musculus) PubMed
698.
structure-function relationships of residues in the fifth transmembrane domain (TM5) of the Na+/H+ antiporter A (NhaA) from Helicobacter pylori [Na+/H+ antiporter] (Mus musculus) PubMed
699.
These results indicate that perturbation of the E-cadherin/beta-catenin complex by H. pylori CagA plays an important role in the development of intestinal metaplasia. (Mus musculus) PubMed
700.
results suggest that ERK and p38 MAPK signalling linked to the TLR2 recognition receptor in human monocytes may be an important pathway in H. pylori-HSP60-induced IL-8 secretion [HSP-60] (Mus musculus) PubMed
701.
Helicobacter pylori formamidase AmiF has a cysteine-glutamate-lysine catalytic triad, as shown by crystallographic analysis (Mus musculus) PubMed
702.
GatCAB is equally efficient in glutamine-dependent transamidation of Asp-tRNAAsn and Glu-tRNAGln [GatCAB] (Mus musculus) PubMed
703.
The H.pylori neutrophil-activating protein is able to bind and condense DNA by a mechanism different from that described for E.coli Dps (neutrophil-activating protein). (Mus musculus) PubMed
704.
Study identified Crk adapter proteins, Rac1 and H-Ras, but not RhoA or Cdc42 as crucial components of the CagA-induced phenotype. (Mus musculus) PubMed
705.
High levels of diversity of activity of CagA H. pylori strains in gastric epithelial cells and its association with polymorphism in CagA gene. [CagA] (Mus musculus) PubMed
706.
provides further evidence for a causal role of CagA+ H pylori infection in the immunopathogenesis of gastric cancer [CagA] (Mus musculus) PubMed
707.
Present work provides useful information for understanding the D-Ala-D-Ala ligase of Helicobacter pylori. (Mus musculus) PubMed
708.
Crystal structure of YbgC was determined and its enzymatic activity was characterized. (YbgC) (Mus musculus) PubMed
709.
These data indicate that the assembly of functional oligomeric VacA complexes is dependent on specific sequences, including amino acids 346 and 347, within the p55 amino-terminal subdomain. [VacA] (Mus musculus) PubMed
710.
the effect of VacA on the secretion of macrophages as an individual virulence determinant [VacA] (Mus musculus) PubMed
711.
Hpn-like (Hpnl) protein, encoded by the hpnl gene in Helicobacter pylori and featuring a histidine-rich and two glutamine-rich motifs, can render nickel tolerance to H. pylori when the external nickel level reaches toxic limits.[hpnl] (Mus musculus) PubMed
712.
cagT can stimulate SGC-7901 cells to express cytokine interleukin-8 and inhibit proliferation [cagT] (Mus musculus) PubMed
713.
in unstable angina patients, immune response against CagA-positive H. pylori strains might be critical to coronary instability mediated by antigen mimicry between CagA antigen and a protein contained in coronary atherosclerotic plaques[CAGA]Review (Mus musculus) PubMed
714.
Study shows a significant proatherogenic effect of H. pylori-secreted factor VacA on a range of vascular endothelial dysfunction markers. (Mus musculus) PubMed
715.
Genotyping of vacA and cagA in H. pylori by a multiplex polymerase chain reaction assay for use in developing countries is reported.[vacA; cagA] (Mus musculus) PubMed
716.
Protein dynamics and flexibility in the activated and inactivated state, respectively, was analysed by probing accessibility in (1)H/(2)H exchange experiments for the wild type and the mutant NhaA which is constitutively active independent of pH.[NhaA] (Mus musculus) PubMed
717.
In China the prevalence of dupA gene was highest in duodenal ulcer and inversely related to gastric ulcer and gastric cancer. (Mus musculus) PubMed
718.
ClpP and ClpA mutants display reduced macrophage and murine survival. [ClpA, ClpP] (Mus musculus) PubMed
719.
inhibition of EGFR endocytosis occurs via a CagA-dependent activation of the non-receptor kinase c-Abl, which in turn phosphorylates the EGFR target site pY1173.[CagA in strain P1] (Mus musculus) PubMed
720.
These data indicate that in some strains of H. pylori, the HopQ outer membrane protein can attenuate bacterial adherence to gastric epithelial cells.[HopQ] (Mus musculus) PubMed
721.
The interactions between HPNikR and the target operator sequences of the genes directly regulated (ureA, NixA, NikR, Fur OPI, Fur OPII, Frpb4, FecA3, and exbB) were characterized.[NikR] (Mus musculus) PubMed
722.
study reports a statistical link between the East Asian CagA EPIYA-ABD genotype and the development of gastric cancer [CagA] (Mus musculus) PubMed
723.
the induction of autophagy by VacA may represent a host mechanism to limit toxin-induced cellular damage [VacA, strain 60190] (Mus musculus) PubMed
724.
findings show that cagA gene is relevant to the expressions of antioxidant proteins of H pylori, which may be a novel mechanism involved in H pylori cagA pathogenesis[cagA] (Mus musculus) PubMed
725.
Virulence factors like cagA and vacA enhance gastric mucosal inflammation & are associated with the development of peptic ulcer & gastric cancer. They induce proinflammatory cytokines. [vacA;cagA] Review. (Mus musculus) PubMed
726.
the neutrophil-activating protein not only plays a role in driving Th1 inflammation but it is also able to inhibit Th2 responses in vitro and in vivo in allergic bronchial asthma, in humans and mice (neutrophil-activating protein; NAP) (Mus musculus) PubMed
727.
Binding of H. pylori adhesins BabA and SabA to the whole range of salivary proteins was explored.[SabA] (Mus musculus) PubMed
728.
A significant correlation between peptic ulceration and the presence of H. pylori isolates carrying cagE and cagA genes was demonstrated in Iranian patients. (cagE and cagA) (Mus musculus) PubMed
729.
results indicate that CagA variants are linked with premalignant lesions in distinct populations and that epithelial responses to these strains are selective based upon locale [CagA] (Mus musculus) PubMed
730.
FldA induction is independent of the Fur protein under iron starvation. [FldA, Fur] (Mus musculus) PubMed
731.
Deletion of FlhB inhibits expression of both RpoN- and FliA- dependent reporter genes. (Mus musculus) PubMed
732.
These studies thus show that the H. pylori CheV proteins each differently affect swimming behaviour. [CheV1, CheV2, CheV3] (Mus musculus) PubMed
733.
The HugZ-haemin complex has been purified and crystallized and diffraction data sets have been collected to 1.8 A resolution.[HugZ] (Mus musculus) PubMed
734.
The secreted Helicobacter cysteine-rich protein A causes adherence of human monocytes and differentiation into a macrophage-like phenotype (Mus musculus) PubMed
735.
The structures of a truncated version of Tipalpha (TipalphaN34) in two crystal forms are presented here (Mus musculus) PubMed
736.
Helicobacter pylori strains isolated from Mexican chronic gastritis patients are highly positive for vacA, cagA and babA2 virulence markers. [vacA, cagA, babA2] (Mus musculus) PubMed
737.
The present study focuses on the metal-binding properties of HpUreE (Helicobacter pylori UreE) and its interaction with the related accessory protein HpUreG.[UreE, UreG] (Mus musculus) PubMed
738.
CagA, vacA s1m1, and iceA1 genotypes are the predominant genotypes of H pylori isolated from the southeastern European pediatric population. [cagA, vacA, and iceA] (Mus musculus) PubMed
739.
findings show that the biological half-life of CagA is about 200 min in gastric epithelial cells; CagA is a relatively short half-life protein whose stability may be modulated through complex formation with PAR1 [CagA] (Mus musculus) PubMed
740.
Using in vitro infection assays, the authors showed that Helicobacter pylori CagA interacts with E-cadherin, p120-catenin, and c-Met. (Mus musculus) PubMed
741.
These results indicated that the oligomeric status of HpHsp60s might have an important role in regulating host inflammation and thus help facilitate H. pylori persistent infection. (Hsp60) (Mus musculus) PubMed
742.
A higher prevalence of more virulent cagA genotype was found in children compared to adults. [cagA] (Mus musculus) PubMed
743.
All 126 isolates possessed cagA, with the majority encoding EPIYA-A (97.6%) and all encoding EPIYA-B. [cagA] (Mus musculus) PubMed
744.
VacA activated NF-kappaB via classical but not alternative pathway. [VacA] (Mus musculus) PubMed
745.
These results revealed that the C-terminal region of HPNAP is indispensable for human neutrophil stimulation and their further adhesion to endothelial cells - a step necessary to H. pylori inflammation.[ HPNAP] (Mus musculus) PubMed
746.
Report distribution of Helicobacter pylori (strain not specified) cagA, cagE, oipA and vacA in different major ethnic groups in Tehran, Iran. (Mus musculus) PubMed
747.
tolC is a critical virulence factor of F. tularensis [tolC] (Mus musculus) PubMed
748.
The identification of the F. tularensis surface protein FsaP is reported, which, when expressed in nonadherent Escherichia coli, confers recombinant bacteria with the ability to bind to A549 cells. (Mus musculus) PubMed
749.
The LpnA-deficient strain showed equivalent ability to promote secretion of chemokines by human monocyte-derived macrophages as its wild-type counterpart.[Tul4] (Mus musculus) PubMed
750.
role in host cell adhesion, virulence, and fiber assembly. [pilT, pilF] (Mus musculus) PubMed
751.
the IglC, IglD, and MglA proteins each directly or indirectly critically contribute to the virulence of F. tularensis LVS, including its intracellular replication, cytoplasmic escape, and inhibition of acidification of the phagosomes.[IglC, IglD, MglA] (Mus musculus) PubMed
752.
the interaction between surface nucleolin and its bacterial ligand EF-Tu plays an important role in Francisella tularensis adhesion and entry process and may therefore facilitate invasion of host tissues [bacterial elongation factor Tu] (Mus musculus) PubMed
753.
The IglA-IglB complex formation is clearly crucial for Francisella pathogenicity.[IglA & IglB] (Mus musculus) PubMed
754.
F. tularensis subsp.holarctica strain LVS prevents neutrophil activation and intramacrophage killing via carA, carB, and pyrB genes, (small and large subunits of carbamoylphosphate synthase and aspartate carbamoyl transferase). [carA, carB, pyrB] (Mus musculus) PubMed
755.
report validation of the predicted route (NaMN --> NMN --> NAD) in F. tularensis including mathematical modeling[nadE] (Mus musculus) PubMed
756.
the cloning, expression, purification and crystallization methods for the class C acid phosphatases from F. tularensis and Pasteurella multocida are reported.[AcpC] (Mus musculus) PubMed
757.
The authors have identified migR (FTL_1542), a gene that regulates expression of the iglABCD operon and is essential for bacterial growth in monocyte-derived macrophages and also contributes to the blockade of neutrophil NADPH oxidase activity.[migR] (Mus musculus) PubMed
758.
The structures show that the core domain supplies the phosphoryl binding site, catalytic histidine (His17), and an aspartic acid residue (Asp261), while the cap domain contributes residues that enforce substrate preference.[ histidine acid phosphatase] (Mus musculus) PubMed
759.
Two crystal forms of KDGK from Thermus thermophilus were obtained by vapour-diffusion and microbatch methods. [2-keto-3-deoxygluconate kinase] (Mus musculus) PubMed
760.
ttMutS2 demonstrated the ability to bind double-stranded (ds) DNA, but, unlike ttMutS, ttMutS2 showed no specificity for mismatched duplexes [mutS2] (Mus musculus) PubMed
761.
three-dimensional NMR solution structure of NusG from Thermus thermophilus, which shows 43% amino acid sequence similarity to the Escherichia coli NusG [NusG] (Mus musculus) PubMed
762.
crystal structure of carboxypeptidase 1 [carboxypeptidase 1] (Mus musculus) PubMed
biochemical properties of the trehalose-6-phosphate synthase (otsA) and trehalose-6-phosphate phosphatase (otsB) in Thermus thermophilus RQ-1 [otsA and otsB] (Mus musculus) PubMed
765.
structures revealed the elements that are responsible for the oligomerization modes. The distributions of the electrostatic potential on the solvent-accessible surfaces suggested putative active sites(Thermus thermophilus HB8, TT1887 and TT1465) (Mus musculus) PubMed
766.
TT1383 is a novel dNTP triphosphohydrolase stimulated by dATP and dTTP (Mus musculus) PubMed
The N-terminal helix was concluded to play no significant role in the specific binding of the S15 protein to its target on 16S rRNA[ribosomal protein S15] (Mus musculus) PubMed
769.
A thermostable beta-ketothiolase from T. thermophilus was isolated and characterized. (Mus musculus) PubMed
770.
crystal structure of the P-protein of the glycine cleavage system from Thermus thermophilus HB8 has been determined; first reported crystal structure of a P-protein [P-protein] (Mus musculus) PubMed
771.
crystal structures of two mutants of Thermus thermophilus EF-G, G16V and T84A, which exhibit Fusidic acid hypersensitivity and resistance in vitro [EG-F] (Mus musculus) PubMed
772.
Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes [ribosomal proteins L12 & L10] (Mus musculus) PubMed
773.
The role of the individual enzyme components on protein maturation and activation of nitrate reductase in T. thermophilus is reported. [nar] (Mus musculus) PubMed
774.
The post-transfer-editing and product complexes of Thermus thermophilus LeuRS (LeuRSTT) with tRNA(Leu) at 2.9- to 3.3-A resolution was described. (LeuRSTT),(tRNA-Leu). (Mus musculus) PubMed
775.
The activity of the separately expressed and purified nucleotide binding domains of ClpB from T. thermophilus is reported.[clpB] (Mus musculus) PubMed
776.
structure and function of the dimanganese catalase are discussed[dimanganese catalase ] (Mus musculus) PubMed
777.
crystal structure of subunit F of vacuole-type ATPase/synthase was determined to of 2.2 A resolution; the subunit F exhibits two conformations, a 'retracted' form in the absence and an 'extended' form in the presence of ATP [V-ATPASE subunit F] (Mus musculus) PubMed
778.
Transition from the GTP-bound to the GDP-bound state involves substantial conformational changes of IF2 and of the entire ribosome. (Mus musculus) PubMed
779.
Using neutron spin-echo spectroscopy (NSE), normal mode analysis, and a statistical-mechanical framework, we reveal overdamped, coupled domain motion within DNA polymerase I from Thermus aquaticus [Taq polymerase] (Mus musculus) PubMed
780.
six of the 12 ancestral mutants of 3-isopropylmalate dehydrogenase tested showed thermal stability higher than that of the original enzyme[3-isopropylmalate dehydrogenase] (Mus musculus) PubMed
781.
comparison of the protein-RNA interactions in the L1-mRNA and L1-rRNA complexes identified amino acid residues of L1 crucial for recognition of its specific targets on the both RNAs [ribosomal protein L1 ] (Mus musculus) PubMed
782.
A study of the Thermus thermophilus chorismate mutase is described by using quantum mechanics (self-consistent-charge density-functional tight binding)/molecular mechanics, umbrella sampling, and the weighted histogram analysis method [chorismate mutase] (Mus musculus) PubMed
783.
X-ray crystallographic study of the L-fuculose-1-phosphate aldolase (FucA) from Thermus thermophilus HB8 [FucA] (Mus musculus) PubMed
784.
Results describe the structure, function, possible mechanism of action and regulation of Gfh1. (Mus musculus) PubMed
785.
rhodanese homologue TTHA0 is crystallized and its molecular structure exmined. (rhodanese homologue TTHA0613 (Mus musculus) PubMed
786.
The crystal structure of EF-Tu x pulvomycin in complex with the guanylyl imino diphosphate at 1.4 A resolution reveals an antibiotic binding site extending from the domain 1-3 interface to domain 2, overlapping the domain 1-2-3 junction.(EF-Tu) (Mus musculus) PubMed
787.
versatile enzyme activities of TthNfo play an important role in counteracting DNA base damage in vivo[endonuclease IV] (Mus musculus) PubMed
788.
Two mutants, containing multiple mutations, were constructed and show greater thermal stabilities than the wild-type and single-point mutant 3-isopropylmalate dehydrogenase (IPMDHs) do. [3-Isopropylmalate dehydrogenase] (Mus musculus) PubMed
789.
Purified/characterized sulfite oxidase from Thermus thermophilus. (Mus musculus) PubMed
790.
Temperature dependence of the structure of the substrate and active site of the chorismate mutase E x S complex was studied. (Mus musculus) PubMed
791.
Report presents the crystal structure of the N-terminal domain of the Thermus thermophilus RNA helicase Hera in complex with adenosine monophosphate (AMP). [RNA helicase Hera] (Mus musculus) PubMed
792.
Data describe the cloning, over-expression, characterization of cognate ligands, and determination of the X-ray crystal structure of a glucose binding protein from Thermus thermophilus [TtGBP]. (Mus musculus) PubMed
793.
We report the presence of Mlc in a thermophilic bacterium; Mlc is the first gene within an operon encoding an ABC transporter for glucose and mannose, including a glucose/mannose-binding protein and two permeases [Mlc] (Mus musculus) PubMed
794.
protein S1 binds in the region of the neck of the 30S ribosomal subunit inducing a conformational change of its structure[Ribosomal protein S1] (Mus musculus) PubMed
795.
2.1 A X-ray structure of FtsY from T. aquaticus bound to GDP [FtsY] (Mus musculus) PubMed
796.
In purified GcpE enzyme, a new transient iron-sulfur-based signal is detected in electron paramagnetic resonance spectroscopy. (Mus musculus) PubMed
797.
the conserved helix 3 of the M domain is specifically required for the DnaK-dependent shuffling of aggregated proteins, but not of soluble denatured substrates, to the pore entrance of the ClpB translocation channel. (ClpB) (Mus musculus) PubMed
798.
ClpB captures substrates on the upper surface of the AAA-1 ring before threading them through the ClpB hexamer in an ATP hydrolysis-driven step. (ClpB) (Mus musculus) PubMed
799.
The crystal structure of T. thermophilus RF2 is similar to the compact structures of E. coli RF2 (RF2). (Mus musculus) PubMed
800.
A network of interaction with the ribosome establishes the active GTP conformation of EF-G and thus facilitates GTP hydrolysis and tRNA translocation.[EF-G] (Mus musculus) PubMed
801.
The structure of protein SI of Thermus thermophilus (M = 61 kDa) in solution at low and moderate ionic strengths (0 M and 100 mM NaCl, respectively) has been studied by small-angle X-ray and neutron scattering. (Mus musculus) PubMed
802.
description of the crystal structure of the Thermus thermophilus ribosome recycling factor (RRF) bound to a 70S ribosomal complex containing a stop codon in the A site, a transfer RNA anticodon stem-loop in the P site and tRNA(fMet) in the E site [RRF] (Mus musculus) PubMed
803.
the crystal structures of the full-length Thermus thermophilus MgtE at 3.5 A resolution, and of the cytosolic domain in the presence and absence of Mg2+ at 2.3 A and 3.9 A resolutions, respectively [MgtE] (Mus musculus) PubMed
804.
dodecins can act as bifunctional cofactor storage proteins that sequester catalytic cofactors in prokaryotes very efficiently in an aggregated and unreactive state[ dodecin ] (Mus musculus) PubMed
805.
Indicate formation of ribonucleoprotein complex composed of aspartyl-tRNA synthetase (DRS2)/tRNA-dependent amidotransferase (AdT)/aspartyl-tRNA involved in asparagine biosynthesis. (Mus musculus) PubMed
806.
is a successful application of this approach to the integral membrane protein Thermus thermophilus cytochrome ba(3) oxidase[cytochrome ba3] (Mus musculus) PubMed
807.
CutA1 proteins from Thermus thermophilus (TtCutA1) and Oryza sativa (OsCutA1) and Pyrococcus horikoshii (PhCutA1)were examined, in order to elucidate the stabilization mechanism of PhCutA1.[CutA1] (Mus musculus) PubMed
808.
confirmed the tetrameric oligomerization state of TrmI[TrmI] (Mus musculus) PubMed
809.
ClpB forms a very dynamic complex, reshuffling subunits on a timescale comparable to steady-state ATP hydrolysis.(ClpB) (Mus musculus) PubMed
computer simulations of the peptidyl transfer reaction in the T. thermophilus ribosome to address the role of L27 [rpmA] (Mus musculus) PubMed
812.
1.9 A resolution structure of Thermus thermophilus proline dehydrogenase inactivated by the mechanism-based inhibitor N-propargylglycine [proline dehydrogenase ] (Mus musculus) PubMed
813.
analysis using molecular dynamics simulations to explain higher fidelity compared to the wild type enzyme [Thermus aquaticus DNA polymerase I] (Mus musculus) PubMed
814.
A recombinant futalosine hydrolase (TTHA0556) of T. thermophilus, which participates in the second step of the pathway and catalyzes the reaction releasing hypoxanthine from futalosine, was prepared and used in functional analyses.[TTHA0556] (Mus musculus) PubMed
815.
study reports the crystal structure of elongation factor P (EF-P) bound to the 70S ribosome along with the initiator transfer RNA N-formyl-methionyl-tRNA(i) (fMet-tRNA(i)(fMet)) & a short piece of mRNA at a resolution of 3.5 angstroms [EF-P] (Mus musculus) PubMed
816.
determined two crystal structures of C-terminal fragments of heat resistant RNA-dependent ATPase from Thermus thermophilus.[DEAD-box RNA Helicase] (Mus musculus) PubMed
817.
Crystal structures of ternary complexes of Thermus thermophilus Ago catalytic mutants with 5'-phosphorylated 21-nucleotide guide DNA and complementary target RNAs of 12, 15 and 19 nucleotides in length [Ago] (Mus musculus) PubMed
818.
AvrXv4 functions like a SUMO protease during Xanthomonas-plant interactions (AvrXv4). (Mus musculus) PubMed
819.
Data suggest that HpaB promotes the secretion of a large set of effector proteins and prevents the delivery of non-effectors into the plant cell [HpaB] (Mus musculus) PubMed
820.
plays an important role in, but is not solely responsible for, both the adaptive and menadione-induced cross-protective responses to H2O2 killing in X. campestris. [katA] (Mus musculus) PubMed
821.
Crystal structure of N-acetylornithine transcarbamylase (Mus musculus) PubMed
822.
Transcription initiation site for virulence factor engA was determined. (Mus musculus) PubMed
823.
expression of both katA(catalase) and ahpC (alkyl hydroperoxide reductase) is controlled by the global peroxide sensor and transcriptional activator, OxyR [KatA, AphC, OxyR] (Mus musculus) PubMed
824.
X-ray analysis of XC229, a conserved hypothetical protein from Xanthomonas campestris (Mus musculus) PubMed
825.
X-ray analysis of XC5357 from Xanthomonas campestris (Mus musculus) PubMed
826.
X-ray characterization of a conserved hypothetical protein XC6422 from Xanthomonas campestris (Mus musculus) PubMed
827.
X-ray crystallographic analysis of XC847, a 3'-5' oligoribonuclease from Xanthomonas campestris [XC847] (Mus musculus) PubMed
828.
The structure of a novel acetylcitrulline deacetylase from Xanthomonas campestris has been solved by multiple-wavelength anomalous dispersion (MAD) using crystals grown from selenomethionine-substituted protein and refined at 1.75 A resolution. (argE) (Mus musculus) PubMed
829.
the determined structure of XC6422 shows that it belongs to the superfamily of serine alpha/beta-hydrolases, with an active site that is fully accessible to solvent owing to the absence of a lid domain [XC6422] (Mus musculus) PubMed
830.
RpfC modulates two different functions (virulence factor synthesis and DSF synthesis) by utilization of a conserved phosphorelay system and a novel domain-specific protein-protein interaction mechanism, respectively[RpfC] (Mus musculus) PubMed
831.
XC5357 ia a putative tetracenomycin polyketide synthesis protein adopting a cupin subfamily structure (XC5357) (Mus musculus) PubMed
832.
The crystal structure of XC847 from Xanthomonas campestris (Mus musculus) PubMed
833.
A novel N-acetylglutamate synthase/kinase bifunctional enzyme of arginine biosynthesis that was homologous to vertebrate N-acetylglutamate synthases was identified in Xanthomonas campestris.[N-acetylglutamate synthase/kinase] (Mus musculus) PubMed
834.
The functional promiscuity discovered for fuconate dehydratase highlights possible structural mechanisms for evolution of function in the enolase superfamily. [fuconate dehydratase] (Mus musculus) PubMed
835.
enzyme from X. campestris could become a good model for mammalian N-acetylglutamate synthase-kinase in structural, biochemical and biophysical studies[N-acetylglutamate synthase-kinase ] (Mus musculus) PubMed
836.
In the present study, the presence of poly ADP-ribose polymerase (PARP)-like activity associated with caspase-3-like protein of Xanthomonas campestris pv. glycines is reported.[caspase-3-like protein] (Mus musculus) PubMed
837.
A single amino acid substitution is sufficient to swap the substrate specificities of N-acetyl-L-ornithine transcarbamylase (N-acetyl-L-ornithine transcarbamylase). (Mus musculus) PubMed
838.
R286A mutation caused XpsE lose the ability to associate with the cytoplasmic membrane via XpsL(N); as a consequence, ATP hydrolysis by XpsE was uncoupled from protein secretion. (XpsE) (Mus musculus) PubMed
839.
The susceptibility of the mutant to unrelated chemicals indicated a general role for OmlA in maintaining membrane integrity.[OmlA in Xanthomonas campestris pv. phaseoli] (Mus musculus) PubMed
840.
The structures of reduced and organic hydroperoxides-oxidized OhrR, visualizing the structural mechanism of OHP induction. (Mus musculus) PubMed
841.
Our findings extend previous work on Clp and RpfF regulation to show that they both influence the expression of pehA in Xcc.[PehA, Clp and RpfF in strain Xc17] (Mus musculus) PubMed
842.
The structure of an intact OGT homolog and kinetic analysis of human OGT variants reveal a contiguous superhelical groove that directs substrates to the active site.[OGT] (Mus musculus) PubMed
843.
In addition to acting as a repressor of putative Zn(2+)-uptake systems, the Zur of the bacterial phytopathogen Xanthomonas campestris acts as an activator of a Zn(2+) efflux pump (Zur). (Mus musculus) PubMed
844.
FlgD comprises two individual domains, a flexible N-terminal domain that cannot be detected in the current study and a stable C-terminal domain that forms a stable dimer[flagellar hook-capping protein ] (Mus musculus) PubMed
845.
The tertiary structures of the apo- and GTP-bound forms of uridylate kinase (UMPK) from the gram-negative plant pathogen Xanthomonas campestris, were determined.[UMPK] (Mus musculus) PubMed
846.
HrcN from the plant pathogenic bacterium Xanthomonas campestris pathovar vesicatoria hydrolyzes ATP and is essential for T3S and bactieral pathogenicity. [HrcN] (Mus musculus) PubMed
847.
Virulence activities of the effector proteins AvrBs1, AvrBs3 and AvrBs4 were uncovered using Agrobacterium-mediated transient expression of the corresponding genes in Nicotiana benthamiana, followed by microscopic analyses.[AvrBs1, AvrBs3, AvrBs4] (Mus musculus) PubMed
848.
XopJ has a role in the inhibition of cell wall-based defense responses. (Mus musculus) PubMed
849.
The crystal structure of XcPqqD was found to adopt a dimer of novel saddle-like fold that revealed considerable differences to the structure predicted de novo and carried out in the absence of suitable template.[PqqD] (Mus musculus) PubMed
850.
XcBCP carries out its oxidoreduction activity through the alternate opening and closing of the substrate entry channel and the disulfide-bond pocket.[BCP] (Mus musculus) PubMed
851.
X-ray structures of Neisseria meningitidis and Xanthomonas campestris MsrB have been determined.[MsrB] (Mus musculus) PubMed
852.
described mutant forms of DctD that activated transcription efficiently from a dctA'-'lacZ reporter gene that possessed the upstream activation sequences (UAS), but not from a reporter gene that lacked the UAS. [DctD] (Mus musculus) PubMed
853.
description of three distinct DNA sequence elements of the ExpG binding sites and their contribution to the specific binding process [ExpG strain2011] (Mus musculus) PubMed
854.
dctA deletion mutants that contain the mutant dctA alleles on a plasmid can proceed further in symbiotic development than null mutants of dctA. (dctA) (Mus musculus) PubMed
855.
findings supported the conclusion that RirA is the mediator of iron-responsive transcriptional repression of the two transcripts encoding the rhizobactin 1021 biosynthesis and transport genes [RirA] (Mus musculus) PubMed
856.
molecular cloning and biochemical characterization including substrate specificity, kinetcs and reaction conditions of L-N-carbamoylase [L-N-carbamoylase] (Mus musculus) PubMed
857.
Molecular model of the DNA-binding domain of FixJ that binds to the fixK promoter (fixj and fixk). (Mus musculus) PubMed
858.
oxygen dramatically inhibited the reaction of the RmFixL-RmFixJ complex with ATP but affected neither ATP binding nor RmFixL-RmFixJ complex formation [FixL, FixJ] (Mus musculus) PubMed
859.
The thermodynamic binding parameters of hydantoin racemase were studied (hydantoin racemase). (Mus musculus) PubMed
860.
The expression of the nolR gene in Sinorhizobium meliloti AK631 was investigated in relation to stage of growth, availability of nutrients, and different environmental stimuli using the nolR::lacZ fusion report system. (Mus musculus) PubMed
861.
bioinformatic, genetic, physiological, biochemical, and structural proof for reassignment of MotD, a protein previously thought to function as a cytoplasmic motility protein as a hook length regulator, FliK [MotD,FliK] (Mus musculus) PubMed
862.
GroEL/GroES production alone cannot explain the requirements for RpoH1 and RpoH2 in S. meliloti. (Mus musculus) PubMed
863.
The major role of BetS is as an emergency system involved in the rapid uptake of betaines in isolated and in planta osmotically stressed bacteroids of S. meliloti. (Mus musculus) PubMed
864.
results suggest that ExpR may repress the expression of motC operon in a low cell density, but this repression can be deprived in a higher cell density [motC; ExpR] (Mus musculus) PubMed
865.
The TolC protein of S. meliloti is assumed to be involved in the excretion of proteins ExsH and ExpE1. (Mus musculus) PubMed
866.
The importance of thioredoxin in melanin production in bacteria, through the regulation of laccase or tyrosinase activities, or both, by the redox state of structural or catalytic SH groups, is discussed. [trxL] (Mus musculus) PubMed
867.
NifA plays a regulatory role in multiple cellular processes in S. meliloti. [NifA] (Mus musculus) PubMed
868.
The authors propose that the distinct CheY2 and CheY2-P surfaces interact with two overlapping sites in the P2 domain that selectively bind either CheY2 or CheY2-P, depending on whether CheA is active or inactive.[CheY2 & CheA in strain RU 13/281] (Mus musculus) PubMed
869.
signalling through the FeuP/FeuQ pathway is responsive to extracellular osmotic conditions, with low osmolarity stimulating ndvA expression.[FeuP, FeuQ in strain SU47] (Mus musculus) PubMed
870.
crystal analysis of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states (Mus musculus) PubMed
871.
The nesR mutant was deficient in competing with the wild-type strain for plant nodulation.[nesR in strain Rm8530] (Mus musculus) PubMed
872.
An ABC transporter plays a role in potassium transport regulation and alkaline stress.[ABC transporter] (Mus musculus) PubMed
873.
The levels of lipids containing C16 fatty acids were decreased in plsC mutant. [plsC] (Mus musculus) PubMed
874.
the crystal structure of ChoX in an unusual, ligand-free conformation that represents a semi-closed form of ChoX. [ChoX] (Mus musculus) PubMed
875.
Rhizobium sp. strain NGR234 possesses a functional type three secretion system through which a number of proteins, called nodulation outer proteins (Nops), are delivered to the outside of the cell. (NopB) (Mus musculus) PubMed
876.
Mutation of nopP leads to a dramatic reduction in nodule numbers on F. congesta and T. vogelii. (Mus musculus) PubMed
877.
biochemical assays show here that NopA, NopB and NopX proteins interact directly with one another.[NopB & NopX] (Mus musculus) PubMed
878.
DNase I footprinting revealed that TtsI occupied not only the tts box consensus sequence, but also upstream and downstream regions in a concentration-dependent manner.[TtsI] (Mus musculus) PubMed
879.
NopJ and NopM are secreted by the type III secretion system. NopM can stimulate nodulation. [NopJ; NopM] (Mus musculus) PubMed
880.
The UPase is a trimer of 43 kD subunits and has a maximal activity at a pH value of 7.8 and 50 degrees C. [Upase] (Mus musculus) PubMed
881.
We confirmed that DspA/E acts as a major cell-death inducer during disease and HR, because the dspA/E mutant is severely impaired in its ability to induce electrolyte leakage in apple and tobacco leaves [DspA/E] (Mus musculus) PubMed
882.
AvrRpt2EA acts as a virulence factor on immature pear fruits. (Mus musculus) PubMed
883.
A major Erwinia amylovora outer-membrane protein (Omp-EA) and the gene encoding for this protein (omp-EA) were isolated and characterized. [Omp-EA] (Mus musculus) PubMed
884.
We sequenced the putative autoinducer-2 (AI-2) synthase gene luxS from E. amylovora (Mus musculus) PubMed
885.
Type three-secreted proteins DspA/E and HrpN induce cell death, activation of defense pathways, and ROS accumulation in Arabidopsis. [DspA/E and HrpN] (Mus musculus) PubMed
886.
Inactivation of luxS impaired motility, extracellular polysaccharide (EPS) production, and tolerance for hydrogen peroxide, and reduced virulence on pear leaves. (Mus musculus) PubMed
887.
Results suggests that the N-terminal and C-terminal halves of HrpN mediate cell-free elicitor activity and avirulence activity, respectively: [HrpN] (Mus musculus) PubMed
888.
The waaL mutant showed reduced in virulence, a decrease in twitching motility, and increase sensitive to polymyxin B. [waaL] (Mus musculus) PubMed
889.
2.0 A resolution crystal structure of the complex between the toxic domain of Colicin D and its immunity protein ImmD (Colicin D and ImmD) (Mus musculus) PubMed
890.
resonance assignment of a 'donor-strand complemented' AfaE from Escherichia coli [AfaE or Afa-3] (Mus musculus) PubMed
891.
CNF1 is a candidate virulence factor in E coli infections in ferrets [CNF1] (Mus musculus) PubMed
892.
Analysis of the pH dependence of enzyme stability provides evidence that stable penicillin acylase conformation is maintained by salt bridges [penicillin acylase] (Mus musculus) PubMed
893.
The saa gene is commonly associated with bovine eae-negative verotoxin-producing Escherichia coli (VTEC) strains but not with ovine or caprine VTEC strains. [saa] (Mus musculus) PubMed
894.
EspG modulates enteropathogen's host cytoskeleton function involving transient microtubule destruction and actin polymerization [EspG] (Mus musculus) PubMed
895.
Data show that expression of TetD activates transcription of a subset of the SoxS/MarA/Rob regulon genes and confers resistance to redox-cycling compounds and antibiotics [TetD]. (Mus musculus) PubMed
896.
An exxmination of crystal structure and substrate specificity of this enzyme (isoaspartyl aminoptidase0 (Mus musculus) PubMed
897.
ParG protein is shown to be a transcriptional repressor of the parFG genes. (ParG protein) (Mus musculus) PubMed
898.
The structure of isoenzyme B (CysM) from Escherichia coli was established in a hexagonal crystal form at 2.7 A resolution. (CysM) (Mus musculus) PubMed
899.
the TolB box sequence in ColE9 is actually larger than the pentapeptide and extends from residues 34 to 46[COLE9] (Mus musculus) PubMed
900.
intrinsic differences between Tir from enterohemorrhagic and enteropathogenic strains of E coli were determined [Tir] (Mus musculus) PubMed
901.
The role of the afaE and afaD genes in the mortality of pregnant rats from intrauterine infection with E. coli is reported.[afaE; afaD] (Mus musculus) PubMed
902.
Results describe the crystal structure of the complex between E. coli RF1 and PrmC bound to the methyl donor product AdoHCy [RF1]. (Mus musculus) PubMed
903.
biochemical analysis of binding of cytochrome bo3 from Escherichia coli (Mus musculus) PubMed
904.
TolC and VceC are interchangeable for the functioning of the AcrAB and VceAB pumps. (VceC) (Mus musculus) PubMed
905.
Recomsbinant F1F0 ATP synthasewas blocked in ATP hydrolysis activity, and this activity was stimulated by the detergent lauryldimethylamine oxide. (F1F0-ATP synthase) (Mus musculus) PubMed
906.
Phosphorylation and dephosphorylation of poly(A) polymerase I (PAP I) effects the activity of the enzyme. (Mus musculus) PubMed
907.
Study reports that EPEC strain B171 produces a functional Cif and that delivery of purified Cif into HeLa cells induces cell cycle arrest and actin stress fibres, implying that Cif is necessary and sufficient for these effects. [Cif protein] (Mus musculus) PubMed
908.
Our results indicate that BarA-UvrY regulates virulence properties in Avian Pathogenic E. coli (APEC) [BARA, UvrY] (Mus musculus) PubMed
909.
fine-tuning of the CRP activity may be critical for bacterial viability and adaptability to changing osmotic conditions [crp] (Mus musculus) PubMed
910.
Results identify the 16-residue TolB binding epitope in the natively disordered T-domain of the nuclease colicin E9 (ColE9) and present the crystal structure of the complex [ColE9]. (Mus musculus) PubMed
911.
Isolates with LEE + HPI gene were more frequently detected in diarrheic swine than in edematous swine and edematous/diarrheic swine.[IEE] (Mus musculus) PubMed
912.
The presence of the tetracycline resistance determinant tet(M) in human clinical isolates of Escherichia coli is described for the first time in this report [tet(M)] (Mus musculus) PubMed
913.
multiple genes associated with biofilm formation are regulated by aggR.[AggR] (Mus musculus) PubMed
914.
Homologous AroQ chorismate mutases from the thermophile Methanococcus jannaschii & the mesophile Escherichia coli were compared as to their capacity to accommodate extensive mutation. There were 10% less functional variants in the E coli AroQ. (Mus musculus) PubMed
915.
Stimulates ATP hydrolysis by ParF approximately 30-fold. The mobile tails of ParG are crucial for this enhancement; arginine R19 within the tail is absolutely required. (ParG) (Mus musculus) PubMed
916.
data suggest that Hbp can fold in the periplasm but must retain a certain degree of flexibility and/or modest width to allow translocation across the outer membrane [Hbp] (Mus musculus) PubMed
917.
The toxicity of EHEC-Hly to microvascular endothelial cells plausibly contributes to the virulence of the stx-negative E. coli O26 strains and to the pathogenesis of HUS. [Hly] (Mus musculus) PubMed
918.
The EAEC strain 60A imp operon differs structurally from previously described homologs [impB, strain 60A] (Mus musculus) PubMed
919.
we observed that MCP-1, and IL-8 to a lower extent, is produced in urine at higher concentrations in UTIs caused by UPECs carrying alpha-hly/cnf1 [cnf1] (Mus musculus) PubMed
Selection for F18(+)E. coli resistant pigs might be an attractive approach to prevent pigs from F18(+)E. coli infections, unlike to what has previously been postulated. (Mus musculus) PubMed
922.
computational analysis of the electrostatic properties of Lpp-56 (Braun's E. coli outer membrane lipoprotein (Lpp-56)) combining molecular dynamics simulations and continuum pK calculations (Mus musculus) PubMed
923.
All four components of the yej locus are required for microcin sensitivity in E. coli.[Yej] (Mus musculus) PubMed
924.
These results show that the DsbA is required for stable expression of outer membrane secretin EscC. [DsbA, EscC in strain 2348/69] (Mus musculus) PubMed
925.
the N-terminal third of mature AIDA-I is involved in binding of this protein to cultured epithelial cells.[Aida-I] (Mus musculus) PubMed
926.
A 3-dimensional map of melibiose permease was calculated from data obtained by electron crystallography. melB. (Mus musculus) PubMed
927.
Enteropathogenic Escherichia coli O125:H6 lacks the ability to utilize either Nck or TccP/TccP2 and hence triggers actin polymerization in vitro only inefficiently.[TccP; TccP2] (Mus musculus) PubMed
928.
Here we demonstrate that NleA compromises the Sec23/24 complex, a component of the mammalian COPII protein coat that shapes intracellular protein transport vesicles, by directly binding Sec24. [NleA] (Mus musculus) PubMed
929.
SitABCD, MntH, and FeoB could potentially promote bacterial survival during infection by facilitating the transport of these trace metals and by countering oxidative stress during infection of the host. [SitA, B, C & D, MntH, FeoB in strain 7122] (Mus musculus) PubMed
930.
mutagenesis study on intimin-binding domain of EPEC TIR & how mutations affect TIR-intimin association; a three-residue TIR hot spot is identified that mediates interaction; mutants altering beta-hairpin structure of TIR diminish binding affinity [TIR] (Mus musculus) PubMed
931.
the results suggest that PapB and FocB can form heterodimers and that these complexes can repress expression of the foc operon.[PapB and FocB in strain J96] (Mus musculus) PubMed
932.
Binding kinetics, mutational analysis and spectroscopic examination of CEA dimers suggest that Dr adhesins can dissociate CEA dimers prior to the binding of monomeric forms.[Dr adhesin] (Mus musculus) PubMed
933.
The superb activity of the 8-oxoguanine glycosylases Fpg, hOGG1, and Ntg1 toward removal of FapyG and FapyA in vitro suggests that these enzymes may act upon these oxidized lesions in vivo.(Fpg) (Mus musculus) PubMed
934.
Hek-mediated adherence is dependent on binding to glycosoaminoglycan. The ability to hemagglutinate, autoaggregate, adhere, and invade is contingent on a putative 25-amino-acid loop that is exposed to the outside of the bacterial cells. (Mus musculus) PubMed
935.
These results suggest that TolC promotes the aggregation and adhesion of EAEC 042 by secreting an assumed humoral factor.[TolC in strain EAEC 042] (Mus musculus) PubMed
936.
In the strain of Escherichia coli K1, data suggest the presence of two domains in the molecular structure of IbeA, with differential unfolding stabilities [IbeA] (Mus musculus) PubMed
937.
The paper demonstrates a direct link between FyuA and biofilm formation in iron-poor environments. [FyuA] (Mus musculus) PubMed
938.
Inserting a Phe near C46 in AhpC makes it inactive as a peroxidase. Some point mutants confer exhibit an enhanced reductase activity toward mixed disulfides between glutathione and glutaredoxin. [AhpC] (Mus musculus) PubMed
939.
Data demonstrate that the conserved 'amphiphilic' feature of HdeA is essential for exhibiting chaperone-like activity under extremely low pH conditions. (Mus musculus) PubMed
940.
the pattern of suppression suggests that two distinct sites on FliG interact with FliM, perhaps with two FliM molecules in a dimer per molecule of FliG.[FliM and FliG in strain HCB1] (Mus musculus) PubMed
941.
the rpoS tnaB double mutant exhibited decreased adherence.[rpoS and tnaB in strain AIEC O83:H1] (Mus musculus) PubMed
942.
GrlA upregulates the expression of LEE through binding of the LEE1 promoter, which in turn increases the level of LEE-encoded regulator allowing it to function as a downstream activator. [GrlA, Lee] (Mus musculus) PubMed
943.
Without l-rhamnose, RhaS does not effectively bind DNA while RhaR does not effectively contact RNAP. Upon l-rhamnose binding, both proteins undergo structural changes that enable transcription activation.[RhaS, RhaR in strain SME3000] (Mus musculus) PubMed
944.
The linkage between class 1 integrans, the dfrA12-orfF-aadA2 cassette array, and sul3 in multidrug resistant E. coli, is reported.[sul3] (Mus musculus) PubMed
945.
findings demonstrate for that immunity release from enzymatic colicins occurs immediately after reduction of the disulfide bond of ColE9s-s leading to unfolding of the helical hairpin [ColE9] (Mus musculus) PubMed
946.
From these data, we speculate that Hly hemolysin (HlyA) and cytotoxic necrotizing factor type 1 (CNF1), may be largely responsible for the signs and symptoms of cystitis in humans infected with toxigenic UPEC. [HlyA, CNF1] (Mus musculus) PubMed
947.
Results describe mapping studies of the epitopes of three NhaA-specific conformational monoclonal antibodies, two of which drastically inhibit the antiporter. (Mus musculus) PubMed
948.
Results describe the crystal structure of QOR2, a new type of NADPH-dependent quinone oxidoreductase from Escherichia coli [QOR2]. (Mus musculus) PubMed
949.
Results present a structural characterisation of a conformational state populated at low pH by the N-terminal domain of Escherichia coli HypF [HypN-F]. (Mus musculus) PubMed
950.
[strain MC4100, genes IbpA and IbpB] IbpA/B protect Escherichia coli cells from oxidative damage caused by copper (Mus musculus) PubMed
the first report of aac (6')-Ib-cr gene in E. coli isolates from food-producing animals [(6')-Ib-cr] (Mus musculus) PubMed
953.
the emergence of CTX-M-1-producing E. coli in western Austria may be attributed to multiple independent events [CTX-M-1] (Mus musculus) PubMed
954.
Our findings suggest that one function of chaperonins may involve trapping unfolded proteins and subsequently exposing them to a microenvironment in which the hydrophobic effect, a crucial thermodynamic driving force for folding, is enhanced. [GroEL] (Mus musculus) PubMed
955.
EspF(U) activates N-Wiskott-Aldrich syndrome protein by competitively disrupting the autoinhibited state [E.Coli O157:H7 strain not specified, EspF(U)] (Mus musculus) PubMed
956.
EspF(U) forms an amphipathic helix that binds the GTPase binding domain, mimicking interactions of the VCA domain in autoinhibited WASP. [E.Coli O157:H7 strain not specified, EspF(U)] (Mus musculus) PubMed
957.
While deletion of the N-terminal affected the expression level of AIDA-I, the protein was still exported to the outer membrane and glycosylated. [AIDA-I] (Mus musculus) PubMed
958.
Results provide experimental evidence for the existence of a stable half-barrel subdomain in the (beta/alpha)8-barrel fold of TrpF [TrpF]. (Mus musculus) PubMed
959.
the solution structure of the apo-thiolation-thioesterase (T-TE) di-domain fragment of the Escherichia coli enterobactin synthetase EntF NRPS subunit [no strain specified; EntF] (Mus musculus) PubMed
960.
demonstrate a magnetic-field effect on the photochemical yield of a flavin-tryptophan radical pair in Escherichia coli photolyase [no strain indicated, DNA photolyase] (Mus musculus) PubMed
961.
A crystal structure of Cif is presented, revealing it to be a divergent member of the superfamily of enzymes including cysteine proteases and acetyltransferases that share a common catalytic triad.[Cif] (Mus musculus) PubMed
962.
crystal structure of Escherichia coli bacterioferritin has been solved to 1.9 A [bacterioferritin] (Mus musculus) PubMed
963.
Antisense ribozymes that act on the DNA gyrase A subunit can also induce recA.[recA, DNA gyrase] (Mus musculus) PubMed
964.
Hsp15 translocates the tRNA moiety from the A site to the P site of stalled 50S subunits. By stabilizing the tRNA in the P site, Hsp15 indirectly frees up the A site, allowing a release factor to land there and cleave off the tRNA. (Mus musculus) PubMed
965.
Both flagellum filament assembly and the motor proteins MotA and MotB appeared to be required for E. coli AL511 uptake into collecting duct cells. [MotA, MotB] (Mus musculus) PubMed
966.
In solution, the periplasmic loop P2 of MalF interacts with MalE in a manner independent of maltose. MalF-P2 adopts a well-defined tertiary structure independent of other parts of the transporter. (MalF) and (MalE) (Mus musculus) PubMed
967.
Glu99 serves as a haem d ligand of cytochrome bd[cytochrome bd quinol oxidase, no strain indicated] (Mus musculus) PubMed
968.
the unique electrostatic network of NhaA that connect the coupled clusters of the "pH sensor" with the binding site, which is crucial for pH activation of NhaA [NhaA, no strain indicated] (Mus musculus) PubMed
969.
The structure of EcoO109I is intrinsically flexible in the direction of its functional movement, to facilitate effective structural changes for sequence-specific DNA recognition and processing.[EcoO109I] (Mus musculus) PubMed
970.
Screening of the mammalian SH3 proteome for the ability to bind EspF(U) identified the SH3 domain of insulin receptor tyrosine kinase substrate (IRTKS), a factor known to regulate the cytoskeleton.[Tir, EspF(U)] (Mus musculus) PubMed
971.
W44 of CusF protein is important in maintaining a moderate-affinity and solvent-shielded three-coordinate environment for Cu(I).[CusF] (Mus musculus) PubMed
972.
Here we demonstrate that the yfiC gene of E. coli encodes an enzyme responsible for the methylation of A37 in tRNA(1)(Val). (Mus musculus) PubMed
973.
The isolation and characterization of 2 closely related antigenic variants of fedA and their association with gastrointestinal disease in swine are reported.[fedA] (Mus musculus) PubMed
974.
study describes structural means by which an enzyme that does not completely enclose its substrate evolved to achieve processive catalysis, and how interactions with DNA flanking the recognition site alter this processivity[DNA ADENINE METHYLTRANSFERASE] (Mus musculus) PubMed
975.
Molecular dynamics study is presented to identify factors that contribute to PmrD protein's stability. [PmrD] (Mus musculus) PubMed
976.
RecF pathway has many parallels with recombinational repair in eukaryotes [recF, unspecified strain] (Mus musculus) PubMed
977.
qnrS1 gene was associated with a Tn3-like transposon[qnrs1] (Mus musculus) PubMed
978.
The IscU-HscB complex exists as two (or more) distinct states that interconvert at a rate much faster than the rate of dissociation of the complex. HscB binds to and stabilizes the ordered state of apo-IscU. (HscB) and (IscU). (Mus musculus) PubMed
979.
The structure of a monothiol GRX homodimer (Escherichia coli GRX4) coordinating a [Fe2S2] cluster is presented. (GRX4). (Mus musculus) PubMed
980.
the function of threonine 44 in Escherichia coli dihydrodipicolinate synthase [dihydrodipicolinate synthase] (Mus musculus) PubMed
981.
By repetitive element sequence-based PCR genotyping, genetic similarity was established for selected isolates. We believe this to be the first report of E. coli strains producing CNF1 in non-human primates. (cytotoxic necrotizing factor 1, cnf1) (Mus musculus) PubMed
982.
There is a correlation between Pet secretion by enteroaggregative Escherichia coli, internalization of Pet into epithelial cells, cell detachment and cell death in EAEC-infected cells.[plasmid-encoded toxin (Pet)/ Escherichia coli 042] (Mus musculus) PubMed
983.
The highest queous accessibility of subunit c of the F1F0 ATP is located in the cytoplasmic side of transmembrane helix 2 and in a pocket of residues around Asp-61. [subunit c of F1F0] (Mus musculus) PubMed
984.
sodA, sodB, gor, trxA, gshA, grxA and marR have distinct roles in safeguarding or sensitizing cells to different toxic metal ions (Cr(2)O(7)(2-), Co(2+), Cu(2+), Ag(+), Zn(2+), AsO(2)(-), SeO(3)(2-) or TeO(3)(2-)). [sodA,sodB,gor,trxA,gshA,grxA and marR] (Mus musculus) PubMed
985.
Electromagnetic coupling of hemes is important for facilitated heme-heme electron transfer in cytochrome bo. [cytochrome bo quinol oxidase] (Mus musculus) PubMed
986.
The structure of the active site of ribonucleotide reductase A chain (PDB 1RIB) in the radical state (tyrosyl radical) was studied using EPR. [ribonucleotide reductase A chain (PDB 1RIB)] (Mus musculus) PubMed
987.
The conformation of the membrane bound, closed channel state of colicin A was determined. (Mus musculus) PubMed
988.
YidC functions as a membrane-based chaperone 'module' to facilitate assembly of a subset of protein complexes in the inner membrane of E. coli.[YidC; Mscl] (Mus musculus) PubMed
989.
These data indicated that AzoR is a quinone reductase providing resistance to thiol-specific stress caused by electrophilic quinones.[AzoR] (Mus musculus) PubMed
990.
This study reports mapping of the ybaW promoter and its expression; it recommends changing the name of the protein to fadM based on its regulation and metabolism.[fadM] (Mus musculus) PubMed
991.
It was shown that over a range of intracellular NagB concentrations it is the quantity of the substrate, GlcN6P, which is limiting growth rather than N-acetylglucosamine-6-phosphate. (Mus musculus) PubMed
992.
The transcriptional regulation of rraB, an inhibitor of RNase E is reported.[rraB; RNase E] (Mus musculus) PubMed
993.
This study showed that, despite differences in FimH structure and fine receptor specificity, the shear-dependent nature of FimH-mediated adhesion is highly conserved between bacterial species.[FimH] (Mus musculus) PubMed
994.
The role of the major periplasmic chaperones in the biogenesis of EspP, a prototype SPATE protein produced by Escherichia coli O157:H7 is reported.[EspP] (Mus musculus) PubMed
995.
new details of the catalytic mechanism of 1-deoxy-D-xylulose 5-phosphate synthase [1-deoxy-D-xylulose 5-phosphate synthase] (Mus musculus) PubMed
996.
the positively charged Skp targets OmpA to a negatively charged membrane, which facilitates the release of OmpA from its complex with Skp for subsequent folding and membrane insertion [E. coli, no strain indicated; ompA and Skp] (Mus musculus) PubMed
997.
A glycine within a flexible beta-strand that links the aminoacylation and editing domains of leucyl-tRNA synthetase was determined to be important to tRNA translocation.[leucyl-tRNA synthetase] (Mus musculus) PubMed
998.
Structural data of FaeG during different stages of the F4 fimbrial biogenesis process confirm the general principles of the donor strand complementation/exchange mechanisms taking place during pilus biogenesis.[FaeG] (Mus musculus) PubMed
999.
PsiB binds to RecA protein that is free in solution. The RecA-PsiB complex impedes formation of RecA nucleoprotein filaments on DNA.(RecA) and (PsiB) (Mus musculus) PubMed
1000.
A phylogenetic analysis of AAN82231 that shows it belongs to the DsbB subfamily of proteins is reported. (Mus musculus) PubMed
1001.
Stabilization and bundling of FtsZ polymers by ZapA was inversely correlated to the GTPase activity of FtsZ.(FtsZ and ZapA) (Mus musculus) PubMed
1002.
In the absence of EntB, EntE catalyzes the formation of Ap(4)A, which is implicated in regulating cell division during stress. EntE expression during iron starvation may produce Ap(4)A to slow growth until intracellular iron stores can be restored. (Mus musculus) PubMed
1003.
The prevalence of cnf, hlyD, sfa, and papGIII in fecal Escherichia coli isolates from healthy dogs and their owners and their association with history of urinary tract infection are reported.[cnf; sfa; papGIII] (Mus musculus) PubMed
1004.
cAMP switches the catabolite activator protein from the 'off' state (inactive), which binds DNA weakly and non-specifically, to the 'on' state (active), which binds DNA strongly and specifically [no strain indicated; catabolite activator protein] (Mus musculus) PubMed
1005.
Rep and UvrD provide two contrasting solutions as to how organisms may promote replication of protein-bound DNA.[Rep] (Mus musculus) PubMed
1006.
Omp1 shows a great sequence & structural homology to the family of outer membrane porins of enteric bacteria; Reconstitution of the purified protein into lipid bilayers demonstrated that it is a channel-forming component & slightly cation-selective[Omp1] (Mus musculus) PubMed
1007.
ChiB hydrolyzes crystalline beta-chitin via a mechanism in which four exposed aromatic residues play important roles (Mus musculus) PubMed
1008.
The digestion of the beta-chitin fibrils by ChiA occurred from the reducing end to the nonreducing end, whereas digestion by ChiB occurred from the non-reducing end to the reducing end [chiA & chiB] (Mus musculus) PubMed
1009.
Amino acid substitution in the omega loop of chromosomal AmpC beta-lactamase in S. marcescens confers resistance to ceftazidime. (Mus musculus) PubMed
1010.
swrW gene encoding putative serrawettin W1 synthetase was identified; putative SwrW was uni-modular nonribosomal peptide synthetase specifying only L-serine [swrW] (Mus musculus) PubMed
1011.
chitin-binding protein CBP21 homologs occur in most chitin-degrading microorganisms,suggesting a general mechanism by which chitin-binding proteins enhance chitinolytic activity. (Mus musculus) PubMed
1012.
Greater retention of the glycosyl fragment at the active site of the -3 mutant of Serratia marcescens chitinase A might favor transglycosylation due to a stabilized conformation of its D313 [chitinase A] (Mus musculus) PubMed
1013.
characterization of polyphosphate operon; it is composed of a polyphosphate promoter, polyphosphate kinase (ppk) and exopolyphosphatase (ppx) [ppk, ppx] (Mus musculus) PubMed
1014.
heme transfer from the soluble HasA hemophore to its membrane-bound receptor HasR is driven by protein-protein interaction from a high to a lower affinity binding site [HasA, HasR] (Mus musculus) PubMed
1015.
SpnT might be involved in regulation of DNA replication and swarming-related phenomenon independent of SpnIR. (SpnT) (Mus musculus) PubMed
1016.
HexS was shown as a LysR type transcriptional regulator; it was a transcriptional negative regulator of the genes swrW encoding serrawettin W1 synthase and PigA for prodigiosin synthesis [hexS] (Mus musculus) PubMed
1017.
while DHasA can bind two heme molecules, it is not able to deliver them to the receptor HasR [HasA, HasR] (Mus musculus) PubMed
1018.
loss of processivity in the W97A mutant was accompanied by a 29-fold increase in the degradation rate for single-polymer chains as present in the soluble chitin-derivative chitosan[chitinase B] (Mus musculus) PubMed
1019.
Mutations in three extracellular loops of HasR abolished hemophore HasA binding both in vivo and in vitro [HasR, HasA] (Mus musculus) PubMed
1020.
Together, these data support a model in which OxyR contributes to early stages of S. marcescens biofilm formation by influencing fimbrial gene expression.[OxyR] (Mus musculus) PubMed
1021.
HasB is specific to heme uptake in the natural host and in Escherichia coli expressing the S. marcescens receptor HasR. (Mus musculus) PubMed
1022.
These results indicate that SmdAB is probably a heterodimeric multidrug efflux pump of the ABC family in S. marcescens.[SmdA & SmdB, in strain Db10] (Mus musculus) PubMed
1023.
E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149. [TME-149] (Mus musculus) PubMed
1024.
Data show that S. marcescens HemTUV permease and HemTUV orthologs present in many gram-negative pathogens form a class of heme-specific permeases different from the Dpp peptide/heme permease characterized in E. coli. Gene Name: HemTUV permease (Mus musculus) PubMed
1025.
Results indicated that activated RssA-RssB signaling directly inhibits flhDC(Sm) promoter activity at 37 degrees C, and this inhibitory effect was comparatively alleviated at 30 degrees C [flhD, flhC, RssA and RssB] (Mus musculus) PubMed
1026.
The gene responsible for multidrug resistance from chromosomal DNA of Serratia marcescens has been cloned. (Mus musculus) PubMed
1027.
The high specificity of the interaction with the (non-chitinous) column material is mediated by aromatic residues that occur in the substrate-binding clefts and surfaces of the enzymes[chitinase C1] (Mus musculus) PubMed
1028.
Three tryptic peptides of the chitosanase are identical to a chitin-binding protein Cbp21 from S. marcescens with 63% sequence coverage. (chitosanase) (Mus musculus) PubMed
1029.
rssC is hierarchically classified as class II members in FlhDC(Sm) regulon, and reciprocally defect in rssC results in aberrant swarming and hypervirulence in S. marcescens.(rssC) (Mus musculus) PubMed
1030.
SdeCDE knockout strains showed no change in antibiotic susceptibility in comparison with the parental strains for any of the substrates.[SdeC, SdeD, SdeE] (Mus musculus) PubMed
1031.
in addition to uptake as N,N'-diacetylchitobiose, a proportion of the N,N'-diacetylchitobiose is converted to N-acetylglucosamine by chitobiase, mainly in the periplasm, and incorporated into the cytoplasm by NagE.[chitobiase in strain 2170] (Mus musculus) PubMed
1032.
SpnR acted as a negative regulator for the production of prodigiosin, swarming motility and biofilm formation, which were regulated by quorum sensing.[SpnR] (Mus musculus) PubMed
1033.
mutations in components of the catabolite repression system (cyaA and crp) eliminate flagellum production and swimming motility. [cyaA, crp] (Mus musculus) PubMed
1034.
role of the (alpha+beta) domain on the stability, catalytic activity and specificity of chitinase A was investigated [chitinase A] (Mus musculus) PubMed
1035.
Three structures of the Serratia marcescens receptor HasR in complex with its hemophore HasA, are presented.[hasA, HasR] (Mus musculus) PubMed
1036.
Results characterize the hydrolytic activities of the chitinase B mutants toward beta-chitin and the soluble chitin-derivative chitosan. (Mus musculus) PubMed
identified ospD1 as a gene whose product negatively controls expression of genes regulated by secretion activity; evidence presented that OspD1 associates with the chaperone Spa15 and MxiE and acts as an anti-activator until it is secreted [OspD1] (Mus musculus) PubMed
1039.
OspG negatively controls the host innate response induced by S. flexneri upon invasion of the epithelium. (Mus musculus) PubMed
1040.
role of Fur and RyhB in the regulation of acid resistance [Fur, RyhB] (Mus musculus) PubMed
1041.
YfiH protein could participate in the same pyrimidine salvage pathway as sfhB gene product[YfiH] (Mus musculus) PubMed
1042.
Expression of both the sit and mntH promoters was repressed by either iron or manganese, partially dependent upon Fur and MntR, respectively. Only the mntH promoter exhibited OxyR-dependent induction in the presence of hydrogen peroxide. [SitA, MntH] (Mus musculus) PubMed
1043.
report the crystal structure of YidB protein at 1.45 A resolution[YidB] (Mus musculus) PubMed
1044.
OspF and OspC1 are essential for polymorphonuclear transepithelial migration. (OspF) (OspC1) (Mus musculus) PubMed
1045.
A Shigella flexneri protein effector OspF as a dually specific phosphatase that dephosphorylated mitogen-activated protein kinases in the nucleus, was identified. (Mus musculus) PubMed
1046.
effects of OspF on the host immune signaling pathways, including those of nuclear factor kappaB(NFkappaB) and MAPKs [OspF] (Mus musculus) PubMed
1047.
IscR was a positive regulator of suf expression in the presence of hydrogen peroxide and a negative regulator of isc expression in the absence of hydrogen peroxide.[IscR in strain SA100] (Mus musculus) PubMed
1048.
We found that coiled-coil regions (CCRs) 2 and 3 are necessary for wild-type Oag chain length regulation by Wzz.[Wzz in strain RMA2162] (Mus musculus) PubMed
1049.
These results suggest that induction of OspF is enhanced during Shigella invasion of dendritic cells and decreases the phosphorylation level of Erk1/2.[OspF] (Mus musculus) PubMed
1050.
The crystal structure of a periplasmic l-aspartate/l-glutamate binding protein (DEBP) from Shigella flexneri complexed with an l-glutamate molecule has been determined and refined to an atomic resolution of 1.0 A.[DEBP] (Mus musculus) PubMed
1051.
The authors present a characterization of the native T3SS ATPase, Spa47, from the cytoplasm of Shigella flexneri, demonstrating it to be in two distinct high-molecular-weight complexes with Spa33: MxiN and MxiK.[Spa47 in strain M90T] (Mus musculus) PubMed
1052.
determination of the crystal structure of VirA at 3.0 A resolution; the fold of VirA is unique and does not resemble that of any known protein [VirA] (Mus musculus) PubMed
1053.
Cys363 within a conserved CXD motif acts as a nucleophile to catalyze ubiquitin transfer through a transthiolation reaction.[IpaH3 in strain 301] (Mus musculus) PubMed
1054.
The residues 206-246 are required for Spa32 binding to the C-terminus of Spa40, an inner membrane protein required for Ipa proteins secretion. (Spa32)(Spa40) (Mus musculus) PubMed
1055.
Overexpression of AcrA gene leads to multidrug resistance in clinical isolates of S. flexneri, and ciprofloxacin acquired susceptible to S. flexneri with Phe-Arg-beta-naphthylamide.[AcrA] (Mus musculus) PubMed
1056.
Findings are consistent with a model in which Skp plays a critical role in the chaperoning of the alpha-domain of IcsA during transit through the periplasm: [Skp] (Mus musculus) PubMed
1057.
Interaction of lipids with IpaB inducec IpaC localization at the needle tip concomitant with translocon insertion into the host membrane and type III secretion induction.[IpaC] (Mus musculus) PubMed
1058.
single base substitution in the oriCIvc of the classical biotype has a significant effect on its replication initiation. [oriC] (Mus musculus) PubMed
1059.
Results define the elements on the phage genome and bacterial chromosome required for CTXphi integration by XerC amd XerD [XerC, XerD] (Mus musculus) PubMed
Data report the crystal structure of the transcriptional activator AphA to 2.2 angstrom resolution [AphA]. (Mus musculus) PubMed
1062.
crystal structure of the outer membrane protein VceC from Vibrio cholerae (Mus musculus) PubMed
1063.
Identification of a complex of TcpC protein and TcpQ protein in the development of the V. cholerae pilus. [TcpC, TcpQ] (Mus musculus) PubMed
1064.
results indicate that HapR autorepresses from a single binding site in the hapR promoter and suggest a model for the temporal regulation of its expression as its intracellular levels increase[HapR] (Mus musculus) PubMed
1065.
results suggest that the differences in FlrC binding to various flagellar promoters results in the differences in transcription levels that mirror the relative requirement for the flagellar components within the flagellum [FlrC] (Mus musculus) PubMed
1066.
The dimer of EpsL in this complex is very similar to the dimer seen in the crystal structure of the native cytoplasmic domain of EpsL [EpsL, EpsE] (Mus musculus) PubMed
1067.
identification of the ToxT binding sites located between acfA and acfD required for transcriptional activation of both genes[ToxT, acfA, AcfD] (Mus musculus) PubMed
1068.
clpB1 insertion mutant showed increased sensitivity towards high temperature, oxidative stress, and acid pH. ClpB1 also conferred thermotolerance to V. cholerae [ClpB1] (Mus musculus) PubMed
1069.
results provide a model for how the genes in the acetoin biosynthetic operon are regulated in V. cholerae by AlsR and AphA in response to environmental signals [AlsR, AphA] (Mus musculus) PubMed
1070.
Crystal structures of a cholera toxin A1 subunit (CTA1):ARF6-GTP (guanosine triphosphate) complex reveal that binding of the human activator elicits dramatic changes in CTA1 subunit loop regions that allow NAD+ to bind to the active site [CTA1] (Mus musculus) PubMed
1071.
small regulatory RNA with diverse functions, ranging from iron homeostasis to the regulation of biofilm formation [RyhB] (Mus musculus) PubMed
1072.
neruaminidase (VCNA)Asp-576 & Arg-577 were specifically labeled with fluorescent substrate suggesting that a flexible beta-turn structure containing this sequence may have a role in the dynamic nature of substrate recognition & catalytic action [VCNA] (Mus musculus) PubMed
1073.
role of NspS in V. cholerae biofilm development; norspermidine activates biofilm formation in an MbaA- and NspS-dependent manner [NspS] (Mus musculus) PubMed
1074.
results provide a model for a two-domain structure for ToxT, with an N-terminal dimerization and environmental sensing domain and a C-terminal DNA-binding domain. [ToxT] (Mus musculus) PubMed
1075.
Fur has both positive and negative regulatory functions in virulence of Vibrio cholerae. (Fur) (Mus musculus) PubMed
1076.
identification of GbpA protein required for efficient intestinal colonization that mediates attachment to both zooplankton and human epithelial cells by binding to a sugar present on both surfaces [GbpA] (Mus musculus) PubMed
1077.
report X-ray crystal structures of T1485 and T1512 and compare them with other structures of similar fold and discuss the putative active site [T1485 and T1512] (Mus musculus) PubMed
1078.
VC0702 may have a biochemical function that involves NTP binding and phosphatase activity of some kind, and is likely involved in regulation of the signaling pathway [VC0702] (Mus musculus) PubMed
1079.
In V. cholerae, VqmA regulates hapR transcription directly by binding to its promoter region and expression of vqmA is cell density dependent and autoregulated. [VqmA; HapR] (Mus musculus) PubMed
1080.
CTA1 utilizes the A1(3) subdomain for functional interaction with ADP-ribosylation factor (ARF) 6 and for efficient expression of in vivo enzyme activity (Mus musculus) PubMed
1081.
ToxT binds independently as a monomer to each toxbox in the tcpA direct repeat. (ToxT) (tcpA) (Mus musculus) PubMed
1082.
the crystal structure of an integron integrase (Vibrio cholerae IntIA) bound to an attC substrate [IntIA] (Mus musculus) PubMed
1083.
Results demonstrate a key role for PrtV in Vibrio cholerae interaction with grazing predators [PrtV]. (Mus musculus) PubMed
1084.
iron transport systems, including a homologue of the ferrous transporter Feo and a periplasmic binding protein-dependent ATP binding cassette (ABC) transport system, termed Fbp, were identified in the V. cholerae genome sequence. [Feo, Fbp] (Mus musculus) PubMed
1085.
Results describe the structure and function of both periplasmic domains of EpsC [EpsC]. (Mus musculus) PubMed
1086.
Repression of type IV mannose-sensitive hemagglutinin (MSHA) was mediated by the key virulence transcription factor ToxT, indicating that V. cholerae is able to coordinate both virulence gene activation and repression.[ToxT] (Mus musculus) PubMed
1087.
HlyU exhibits structural features common to the SmtB/ArsR family of transcriptional repressors (HlyU). (Mus musculus) PubMed
1088.
EpsE ATP hydrolysis is stimulated by EpsL and acidic phospholipids [EpsL, EpsE] (Mus musculus) PubMed
1089.
Study identifies the nucleoid protein Fis as playing a major role in the V. cholerae quorum-sensing circuit.[Fis protein] (Mus musculus) PubMed
1090.
The vpvC allele found in the rugose genetic background is more active at producing c-di-GMP while that in smooth genetic background is less active. [vpvC] (Mus musculus) PubMed
1091.
We found that gene expression of this PTS system is influenced by catabolite regulation and also by an Mlc homologue (VC2007), which in E. coli is a global regulator of sugar metabolism. [Mlc] (Mus musculus) PubMed
1092.
the essential function of CgtA is as a repressor of the stringent response that acts by regulating SpoT activity to maintain low ppGpp levels when bacteria are growing in a nutrient-rich environment [CgtA, SpoT] (Mus musculus) PubMed
1093.
The results here provide a model for the dual activation of the aphA promoter by Lrp and VpsR as well as its dual repression by HapR and AphA.[HapR, AphA, Lrp, VspR] (Mus musculus) PubMed
1094.
The crystal structure of HapR to 2.2-A resolution reveals a dimeric, two-domain molecule with an all-helical structure that is strongly conserved with members of the TetR family of transcriptional regulators.[HapR protein] (Mus musculus) PubMed
1095.
These data provide compelling evidence of a role for dynamics in the catalytic cycle of DsbA.[DsbA] (Mus musculus) PubMed
1096.
It was shown that under hydrodynamic conditions biofilms were formed independent of VspA and LuxO but were controlled by expression of RpoS a negative regulator of VpsA. [VpsA, LuxO, RpoS] (Mus musculus) PubMed
1097.
The ability of V. cholerae to prevent clearance and establish this prolonged colonization was associated with the accessory toxins hemolysin, the multifunctional autoprocessing RTX toxin, and hemagglutinin/protease.[HlaA, RtxA, HapA] (Mus musculus) PubMed
1098.
Hemolysin had the predominant role in lethality, with a secondary contribution by the multifunctional autoprocessing RTX (MARTX) toxin.[HlyA, RtxA] (Mus musculus) PubMed
1099.
Our results indicate that cyclic AMP receptor protein (CRP) plays a crucial role in the V. cholerae life cycle by affecting quorum sensing and multiple genes required for survival of V. cholerae in the human host and the environment. [CRP] (Mus musculus) PubMed
1100.
characterization of a unique chitin oligosaccharide deacetylase involved in chitin catabolic cascade in the marine bacterium Vibrio cholerae [chitin oligosaccharide deacetylase] (Mus musculus) PubMed
1101.
results indicate that specific residues of OmpU play different roles in controlling the passage of various compounds [OmpU] (Mus musculus) PubMed
1102.
these results support a main role of HlyA in the pathogenesis of the CT gene-negative V. cholerae non-O1, non-O139 strain and identify apoptosis as a previously unrecognized cell death pathway triggered by HlyA.[HlyA in strain VC175] (Mus musculus) PubMed
1103.
results suggest a model for the regulatory input of cyclic AMP (cAMP) receptor protein (CRP) on exopolysaccharide biosynthesis [CRP] (Mus musculus) PubMed
1104.
Analysis of the truncated EpsM mutants revealed that the region of EpsM from amino acids 100 to 135 is necessary for EpsM to form homo-oligomers, while residues 84 to 99 appear to be critical for a stable interaction with EpsL. [EpsM, EpsL] (Mus musculus) PubMed
1105.
Comparison among 4 x-ray structures of MsbA, trapped in different conformations (2 nucleotide-bound structures & 2 without nucleotide) reveals a flexible hinge formed by extracellular loops 2 & 3, allowing large ranges of motion. MsbA. (Mus musculus) PubMed
1106.
FabV defines a new class of enoyl-ACP reductase.[FabV] (Mus musculus) PubMed
1107.
The 3D structure of hemagglutinin/protease [HA/P (vibriolysin)] was predicted based on its sequence homology with Pseudomonas aeruginosa elastase (HA/P). (Mus musculus) PubMed
1108.
study found that the major MSHA pilin, MshA, was degraded in V. cholerae in a TcpJ-dependent fashion [MSHA, TcpJ] (Mus musculus) PubMed
1109.
Data show that HapR, a major regulator of quorum sensing, binds to and directly represses the expression of the biofilm transcriptional activator, vpsT [vpsT] (Mus musculus) PubMed
1110.
Results identify the key structural elements which complement the N-terminal part of FliMV and explain how the structure, shape, and surface properties of the FliM binding pocket of other CheYVs abrogate this function [FliM]. (Mus musculus) PubMed
1111.
environmental strains of V. cholerae isolated from different aquatic biotopes in Kerala produced toxigenic non-O1/non-O139 strains harboring CTX genetic element, heat-stable enterotoxin, rtxA gene, El Tor hemolysin, & Vibrio pathogenicity island.[rtxA] (Mus musculus) PubMed
1112.
Lrp negatively regulates its own gene in E. coli, and was shown to do so even more strongly in P. mirabilis, Lrp appears to activate its own gene in V. cholerae.[Lrp] (Mus musculus) PubMed
1113.
LqsA and CqsA belong to a family of pyridoxal 5'-phosphate-dependent autoinducer synthases, which produce the alpha-hydroxyketone signaling molecules LAI-1 and CAI-1 (Mus musculus) PubMed
1114.
The extracellular matrix components fibronectin and fibrinogen were degraded by PrtV (PrtV). (Mus musculus) PubMed
1115.
The X-ray crystal structure of lysostaphindetermined at 1.9-A resolution, is reported.[Lysostaphin] (Mus musculus) PubMed
1116.
study found that the Vibrio cholerae hemolysin HlyA oligomer induced the expression of CXCR3 on B-1a cells [HlyA] (Mus musculus) PubMed
1117.
The data indicate that VciB functions by promoting iron uptake via a ferrous, but not ferric, iron transport system: [VciB] (Mus musculus) PubMed
1118.
hapR expression is also modulated by the regulatory network that governs flagellar assembly[hapR litR] (Mus musculus) PubMed
1119.
Cholera toxin B, a component of Vibrio cholerae, promotes autoantibody production and glomerulonephritis in lupus-prone mice by enhancing lipid raft aggregation in T cells. (cholera toxin B) (Mus musculus) PubMed
1120.
study identified two new genes, cdgG & cdgH, involved in rugosity control; determined that CdgH acts as a diguanylate cyclase (DGC) and positively regulates rugosity, whereas CdgG does not have DGC activity and negatively regulates rugosity [CdgG, CdgH] (Mus musculus) PubMed
1121.
Helical arrays of membrane reconstituted MsbA are sensitive to subtle conformational changes induced by various transition state inhibitors. (MsbA) (Mus musculus) PubMed
1122.
Vibrio cholerae ToxT uses different mechanisms in transcriptional regulation of pro- and anticolonization factors. [ToxT] (Mus musculus) PubMed
1123.
The authors provide evidence that EpsD is critical to the localization of EpsC and EpsM and perhaps their assembly into the T2S complex.[EpsD & EpsC & EpsM] (Mus musculus) PubMed
1124.
analysis provides evidence that HapR binds to two distinct binding motifs and has led to the identification of several novel HapR-regulated targets in V. cholerae (HapR). (Mus musculus) PubMed
1125.
ACT domain is essential for (p)ppGpp hydrolase activity of SpoT. [SpoT] (Mus musculus) PubMed
1126.
This transcriptional regulator, OscR (osmolarity controlled regulator), was found to modulate the transcription of genes involved in biofilm matrix production and motility in a salinity-dependent manner. New Gene: OscR (Mus musculus) PubMed
1127.
Data indicate that FlhF establishes the site of flagellum assembly at the old cell pole membrane by recruiting the earliest flagellar structural component FliF [FlhF]. (Mus musculus) PubMed
1128.
preliminary X-ray studies to 1.71 A resolution.[EpsH] (Mus musculus) PubMed
1129.
Data present the apo- and PLP-bound crystal structures of CqsA and confirm that it shares structural homology with the dimeric alpha-oxoamine synthases, including a conserved PLP-binding site [CqsA]. (Mus musculus) PubMed
1130.
Results suggest a model in which GbpA levels fluctuate in concert with the bacterial production of proteases in response to quorum-sensing signals. [GbpA] (Mus musculus) PubMed
1131.
This study showed that PhoB regulates an operon, acgAB, which encodes cyclic diguanylic acid metabolic enzymes and that induction of acgAB by PhoB positively regulates V. cholerae motility and acgAB expression during late stages of cholera in mice. (Mus musculus) PubMed
1132.
The pH optimum of MgPP(i) hydrolysis by PPase was shifted to more alkaline pH due to higher values of the pK(a) of ionizable groups for both the free enzyme and the enzyme-substrate complex. [PPase] (Mus musculus) PubMed
1133.
Thermal instability in the CTA1 subunit-specifically, the loss of CTA1 tertiary structure at 37 degrees C-triggers toxin dislocation.[CTA1] (Mus musculus) PubMed
1134.
V. cholerae biofilm and planktonic cells differ in cell-to-cell communication by differentially responding to autoinducer 2. A V. cholerae luxS (autoinducer-2-defective) mutant made increased biofilm. [autoinducer 2/AI-2/Vibrio cholerae strain C7258] (Mus musculus) PubMed
1135.
The regulation of thermostable direct hemolysin-related hemolysin (trh) transcription via its promoter region in V. parahaemolyticus. [trh] (Mus musculus) PubMed
Three new regulators of swarming, swrZ, swrT, and opaR [swrZ, swrT, and opaR] (Mus musculus) PubMed
1138.
These results indicate that the pvsC gene product functions as an inner membrane exporter of vibrioferrin. [PvsC] (Mus musculus) PubMed
1139.
Two proteins, psuA and pvuA, are immunogenic and can produce synergistic effects during in vivo infection. (psuA and pvuA) (Mus musculus) PubMed
1140.
Vibrio VopL is predicted to be a bacterial virulence factor that disrupts actin homeostasis during an enteric infection of the host. (Mus musculus) PubMed
1141.
ScrC has intrinsic diguanylate cyclase and phosphodiesterase activities, that are controlled by ScrAB. Specifically, ScrC acts to form c-di-GMP and the phosphodiesterase activity plays a dominant role during surface translocation and in biofilms. [ScrC] (Mus musculus) PubMed
1142.
The cytotoxicity against flounder gill cells and fish pathogenicity indicated a potential role for the zinc metalloprotease in pathogenesis. [Zinc metalloprotease] (Mus musculus) PubMed
1143.
VmeA and VmeB genes encode an RND type of multidrug efflux transporter. [VmeA, VmeB] (Mus musculus) PubMed
1144.
These phenotypes were abrogated in a mutant strain lacking the CI-T3S effector Vp1686, suggesting that the inhibiting actin polymerization may be a downstream effect of Vp1686-dependent GTPase inhibition.[Vp1686 in strain BCC23] (Mus musculus) PubMed
1145.
ExsA positively regulates the expression and secretion of Vp1656 while ExsD negatively regulates the expression and secretion of Vp1656. [ExsA, ExsD] (Mus musculus) PubMed
1146.
Results support insertion sequence-mediated partial tdh deletion resulted in the emergence of the tdh(-) strain (tdh). (Mus musculus) PubMed
1147.
study reports the crystal structure of a member of the solute sodium symporters, the Vibrio parahaemolyticus sodium/galactose symporter [SGLT] (Mus musculus) PubMed
1148.
These findings demonstrated the behavior of MreB in the morphological changes of V. parahaemolyticus under intrinsic or extrinsic stresses.[MreB in strain 1137] (Mus musculus) PubMed
1149.
VopQ is a type III secreted effector essential for T3SS1-mediated cytotoxicity that induces autophagy during infection in a phosphatidylinositol-3-kinase-independent manner. [VopQ] (Mus musculus) PubMed
1150.
Results suggest that Vibrio vulnificus hemolyin/cytolysin VvhA is substantially produced in vivo and would contribute to the pathogenesis of V. vulnificus septicemia [VvhA strain MO6-24/O] (Mus musculus) PubMed
1151.
adenylate cyclase of V. vulnificus appeared to play a global regulatory role in the expression of various virulence factors[cya, adenylate cyclase] (Mus musculus) PubMed
1152.
cloning and characterization of PilA; role in bioilm formation, adherence to epithelial cells, and virulence. [PilA] (Mus musculus) PubMed
1153.
cadBA genes were transcribed as a transcriptional operon by a single promoter, P(cadBA), which was activated by CadC in a pH-dependent manner [CadC] (Mus musculus) PubMed
1154.
flagellin FlaB would serve as an efficacious mucosal adjuvant inducing protective immune responses through TLR5 activation. (FlaB) (Mus musculus) PubMed
1155.
Essential in both the pathogenesis and the capsular polysaccharide biosynthesis of V. vulnificus. (wbpP, UDP-N-acetyl-D-glucosamine C4 epimerase) (Mus musculus) PubMed
1156.
findings demonstrate that PGI-LysAP has broad exopeptidase activity which may enhance V. vulnificus invasiveness by altering peptides involved in signal transduction pathways [PGI-LysAP] (Mus musculus) PubMed
1157.
Cyclo(Phe-Pro)produced by Vibrio vulnificus upregulates the expression of ompU [ompU] (Mus musculus) PubMed
1158.
PutR and CRP coactivate the expression of putAP operon promoter and exert their effect by cooperatively binding to the promoter. (PutR) (cAMP receptor protein) (Mus musculus) PubMed
1159.
vvhA expression in swarming V. vulnificus is downregulated via the activity of the LuxS quorum-sensing system. (vvhA) (luxS) (Mus musculus) PubMed
1160.
these results demonstrate that AphB and CadC function sequentially in a regulatory cascade to activate cadBA expression and that AphB activates the expression of cadC by directly binding to an upstream region of P(cadC).[AphB, CadC] (Mus musculus) PubMed
1161.
This study indicates that OmpU is an important virulence factor involved in the adherence of V. vulnificus to the host cells. (Mus musculus) PubMed
1162.
SoxR induces CadA (lysine decarboxylase)in response to superoxide stress [SoxR, CadA] (Mus musculus) PubMed
1163.
study demonstrates novel findings that NtrC is involved in biofilm formation and that NtrC modulates LPS and EPS production via controlling expression of the gene encoding an ADP-glycero-manno-heptose-6-epimerase(gmhD) [ntrC, gmhD] (Mus musculus) PubMed
1164.
VvpE has a role in the surface adherence and colonization of V. vulnificus by facilitating swarming, and in the mucosal invasion of V. vulnificus by destroying IgA and lactoferrin. (Mus musculus) PubMed
1165.
These findings suggest that interaction with membrane cholesterol is required for activity of Vibrio vulnificus cytolysin. (VVC) (Mus musculus) PubMed
1166.
Loss of PilD or PilA significantly reduces the ability of V. vulnificus to persist in Crassostrea virginica over a 66-h interval, strongly suggesting that pili expressed by this bacterium play a role in colonization or persistence in oysters. [PilD, PilA] (Mus musculus) PubMed
1167.
IlpA of V. vulnificus functions as an immunostimulant to human cells via TLR2 (Mus musculus) PubMed
1168.
results indicate that phospholipase A (PLA)activity is important in V. vulnificus-induced cytotoxicity and lethality, suggesting a crucial role for PLA in the pathogenesis of V. vulnificus infection [PLA] (Mus musculus) PubMed
1169.
gne, but not galE, is essential for LPS biosynthesis and virulence in the zoonotic serovar of V. vulnificus biotype 2 [gne] (Mus musculus) PubMed
1170.
Nonribosomal peptide synthase genes (vvsA, vvsB) are responsible for the biosynthesis of siderophore in Vibrio vulnificus MO6-24/O are important for virulence of the pathogen in a mice model. [vvsA, vvsB] (Mus musculus) PubMed
1171.
Metalloprotease (vvp) and the extracellular serine protease (vvhA) contribute to pathogenicity of V. vulnificus. [vvp, vvhA] (Mus musculus) PubMed
1172.
The 34 kDa-VvpE is the major form secreted along with 45 kDa-VvpE from the early growth phase via the PilD-mediated type II general secretion system. [VvpE, pilD] (Mus musculus) PubMed
1173.
These results provide evidence that csrA inhibits biofilm formation in V. vulnificus.[CsrA] (Mus musculus) PubMed
1174.
We conclude that fadR and regulation of fatty acid metabolism are essential for V. vulnificus to be able to cause disease in mammalian hosts.[FadR] (Mus musculus) PubMed
1175.
Taken together, these results indicate that V. vulnificus RtxA toxin induces the apoptotic death through a mitochondria-dependent pathway in human intestinal epithelial cells exposed to V. vulnificus.[RtxA in strain MO6-24/O (Mus musculus) PubMed
CadC and leucine responsive regulatory protein (Lrp) function cooperatively to activate the cadBA operon rather than sequentially in a regulatory cascade. [CadC, Lrp] (Mus musculus) PubMed
1178.
The quaternary structure of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus was determined after co-crystallization with a nanobody. (EpsI and EpsJ). (Mus musculus) PubMed
1179.
HupA of V. vulnificus is essential for survival and multiplication during infection. (Mus musculus) PubMed
1180.
Two regulators of ribonuclease activity, RraAV1 and RraAV2, have both a conserved inhibitory function and a differential inhibitory activity on RNase E-like enzymes across the species. (RraAV1)(RraAV2) (Mus musculus) PubMed
1181.
The nanA mutant was significantly diminished in growth with and adherence to INT-407 epithelial cells in vitro, and was defective for intestinal colonization.[NanA] (Mus musculus) PubMed
1182.
pilA allelic diversity and horizontal movement is maintained in the population by both diversifying and frequency-dependent selection most likely to escape shellfish innate immunity defense or lytic phages.[pilA] (Mus musculus) PubMed
1183.
These results indicate that iron increases extracellular VvhA secretion via the type II general secretion system, although it can repress vvhA transcription via Fur.[vvhA] (Mus musculus) PubMed
1184.
Low temperature incubation of the parent resulted in loss of catalase activity, making the cells H(2)O(2) sensitive, and paralleling the loss of culturability (entry into the viable but nonculturable state).[catalase] (Mus musculus) PubMed
1185.
resultant data show that C. trachomatis DcrA binds to native chlamydial genomic sequences and, overall, substantiate a functional relationship between chlamydial DcrA and the Fur family of regulators [DcrA strain E/UW-5CX] (Mus musculus) PubMed
1186.
concluded that PrmC functions as an N5-glutamine AdoMet-dependent MTase, involved in methylation of release factors [PrmC strain L2/434/Bu] (Mus musculus) PubMed
1187.
Functional surface expression, coupled with improved understanding of major outer membrane protein (MOMP) topology, could provide modified antigens for immunological studies and vaccination, including live subunit vaccines.[MOMP] (Mus musculus) PubMed
1188.
GroEL increased the ability of HrcA to bind to the CIRCE operator and to repress transcription [GroEL, HrcA] (Mus musculus) PubMed
1189.
The association between clinical symptoms and ompA genotype or serotype in patients with C. trachomatis infections is presented.[ompA] (Mus musculus) PubMed
1190.
cloning and expression of Chlamydia trachomatis inclusion membrane protein genes IncB and IncC in Escherichia coli. [IncB, INcC] (Mus musculus) PubMed
1191.
These findings provide the first genetic proof that TrpR acts as a negative regulator of transcription in C. trachomatis. (Mus musculus) PubMed
1192.
The omp1 gene was highly conserved for genotype E and F, but less conserved for other genotypes. [omp1] (Mus musculus) PubMed
1193.
ChlaDub1 and ChlaDub2 represent the first known bacterial deubiquitinating enzymes (DUBs) that possess both deubiquitinating and deneddylating activities. (Mus musculus) PubMed
1194.
CT229 of Chlamydia trachomatis interacts with and recruits Rab4A to the inclusion membrane and therefore may play a role in regulating the intracellular trafficking or fusogenicity of the chlamydial inclusion.(CT229) (Mus musculus) PubMed
1195.
results indicate RNAP containing sigma(28) is capable of recognizing some but not all E coli sigma(28)-dependent promoters & it can distinguish different promoter structures, preferentially activating promoters with upstream AT-rich sequences [sigma28] (Mus musculus) PubMed
1196.
Results reveal a mechanism by which chlamydiae induce localized cytoskeletal changes by the translocated effector TARP (translocated actin recruiting phosphoprotein) during entry into host cells [TARP]. (Mus musculus) PubMed
1197.
chlamydial protease-like activity factor mediated anti-chlamydial immunity is highly dependent upon antigen-specific CD4(+) T cells[chlamydial protease-like activity factor] (Mus musculus) PubMed
1198.
We found that expression of cHsp60-2 is responsive to iron deprivation in endometrial epitheliala cells in vitro. [Hsp60-2] (Mus musculus) PubMed
1199.
LpxD is the N-acyltransferase of lipid A biosynthesis [LpxD for serovar B] (Mus musculus) PubMed
1200.
A novel C. trachomatis antihost protein whose activity is relevant to chlamydial pathogenesis has been discovered.[CT847] (Mus musculus) PubMed
1201.
chaperone activity may involve functional protease domain and that Chlamydia trachomatis HtrA functions as both a chaperone and protease at 37 degrees C[ HtrA ] (Mus musculus) PubMed
1202.
Data show that CdsF is concentrated in the outer membrane of elementary bodies and is surface exposed as a component of an extracellular needle-like projection, and could serve as an efficacious target for anti-Chlamydia neutralizing antibodies[CdsF] (Mus musculus) PubMed
1203.
Examination of the reactivities of three stable redox states of the Mn/Fe cluster of ribonucleotide reductase R2 subunit toward hydrogen peroxide (ribonucleotide reductase R2). (Mus musculus) PubMed
1204.
F41A mutation increases the K(M) for UDP-3-O-(R-3-OHC14)-GlcN 30-fold, consistent with aromatic stacking of the corresponding F43 side chain against the uracil moiety of bound UDP-GlcNAc in the X-ray structure of Chlamydia trachomatis LpxD[LpxD] (Mus musculus) PubMed
1205.
Tarp harbors a sequence similar to a Src and Abl kinase consensus target. (Tarp) (Mus musculus) PubMed
1206.
cHSP60 and cHSP10 could affect mucosal immune function by increasing the release of IFN-gamma, IL-10 and TNF-alpha by cervical mononuclear cells. HSP60. HSP10. (Mus musculus) PubMed
1207.
ChlaDub1 is capable of inhibiting IkappaBalpha degradation and blocking NF-kappaB activation. (ChlaDub1) (Mus musculus) PubMed
1208.
7 of the 12 sigma-66 promoters were poorly conserved across C. trachomatis, Chlamydia pneumoniae and Chlamydia caviae. [sigma-66] (Mus musculus) PubMed
1209.
Amino acid residues E206, Y214, and E222 of sigma 28 contribute to interaction with the core RNA polymerase. [sigma 28] (Mus musculus) PubMed
1210.
These results indicate that nectin-1 is degraded by chlamydial protease-like activity factor (CPAF) in C. trachomatis-infected genital epithelial cells, a novel strategy that Chlamydiae may use to aid their dissemination. [CPAF] (Mus musculus) PubMed
1211.
The findings show that PmpD exists as two distinct forms, a surface-associated oligomer exhibiting a higher-order flower-like structure and a soluble form restricted to infected cells.[PmpD in strain L2/LGV-434] (Mus musculus) PubMed
1212.
Tarp was translocated into the host cell cytoplasm where it is phosphorylated by a set of host protein kinases. [Tarp] (Mus musculus) PubMed
1213.
the aminoacid sequences of the human HSP60 was compared with the bacterial counterpart to better elucidate how CTHSP60 may simulate HSP60 from human origin during infection and may induce an autoimmune response.(CTHSP60) (Mus musculus) PubMed
1214.
Substrate cleavage is also correlated with processing of CPAF into N-terminal (CPAFn) and C-terminal (CPAFc) fragments, suggesting that these putative catalytic residues may also be required for CPAF maturation [CPAF] (Mus musculus) PubMed
1215.
YtgA is an iron-binding protein that is influenced specifically by iron availability, and may be part of an ABC transporter system. [YtgA(CT067)/Chlamydia trachomatis E/UW-5/CX] (Mus musculus) PubMed
1216.
Below the major thermal transition regions, nMOMP remains in its native conformation over the pH range of 3-8. Above the thermal transitions, nMOMP appears in two different structurally altered states; one at pH 3-5 and the other at pH 6-8. (MOMP) (Mus musculus) PubMed
1217.
The authors demonstrated that CT621 is secreted late in the chlamydial developmental cycle and that it is the first chlamydial protein found to be localized within both the host cell cytoplasm and the nucleus.CT621] (Mus musculus) PubMed
1218.
By use of UDP-MurNAc-L-Ala-D-Glu as the nucleotide substrate, MurE(Ct) demonstrated ATP-dependent meso-diaminopimelic acid ligase activity with pH and magnesium ion optima of 8.6 and 30 mM, respectively.[MurE] (Mus musculus) PubMed
1219.
Results identify Tyt1 as the first bacterial NSS member consisting of only 11 TMs and shows that Tyt1 is a suitable model for the study of neurotransmitter:sodium symporter (NSS) dynamics and structure/function relationships of human NSSs [Tyt1}. (Mus musculus) PubMed
1220.
X-ray structure; FadA exists in two forms: the intact form (pre-FadA), consisting of 129 amino acids, and the mature form (mFadA), which lacks an 18-residue signal sequence. The crystals belong to the hexagonal space group P6(1) or P6(5)[FadA]. (Mus musculus) PubMed
1221.
FadA from Fusobacterium nucleatum secreted and nonsecreted forms are used for functional oligomerization for attachment and invasion of host cells (Mus musculus) PubMed
1222.
Fnu_GT displayed the highest glycosylation activity when UDP-galactose was used as a donor nucleotide-sugar and heptose or Nacetylglucosamine as an acceptor sugar. [GT] (Mus musculus) PubMed
1223.
[fomA] Conformation and orientation of membrane-incorporated FomA demonstrate by selective interaction with phosphatidylcholine bilayer membranes that FomA is not trimeric, and is consistent with a monomeric beta-barrel of 14-16 strands. (Mus musculus) PubMed
1224.
Arginine-inhibitable adherence in co-aggregation and biofilm formation is specifically mediated by radD. [RadD] (Mus musculus) PubMed
1225.
FadA plays an important role in F. nucleatum colonization in vivo. (Mus musculus) PubMed
1226.
Recombinant GR from Fusobacterium nucleatum (FnGR), a Gram-negative anaerobe involved in periodontal disease, was overproduced, purified, and characterized. [glutamate racemase] (Mus musculus) PubMed
1227.
R290 & F31 provide catalytic power for hydrolysis of both substrates, native residues are more important for 4NPX than 4NPA as xylopyranose ring must undergo greater distortion than arabinofuranose ring[beta-D-xylosidase/alpha-L-arabinofuranosidase] (Mus musculus) PubMed
1228.
crystallization and structure at 1.8 A resolution of DNA photolyase devoid of its 8-HDF chromophore (apophotolyase) [DNA photolyase] (Mus musculus) PubMed
1229.
crystal structure of DNA photolyase bound to duplex DNA that is bent by 50 degrees and comprises a synthetic cyclobutane pyrimidine dimer lesion [DNA photolyase] (Mus musculus) PubMed
1230.
genetic analysis of glnN promoter region; non-canonical NtcA-binding motif is responsible for NtcA-dependent, nitrogen-responsive regulation of glnN; P(II) signalling protein has opposing effects on NtcA-dependent glnN expression [glnN] (Mus musculus) PubMed
1231.
SipA identified as a sensor histidine kinase non-bleaching sensor (NblS) interacting protein, at the ATP binding domain. [SipA, Nbls] (Mus musculus) PubMed
1232.
PsR domain of CikA negatively regulates histidine protein kinase activity in vivo and also serves as an interaction module to dock CikA at a specific subcellular location. [CikA] (Mus musculus) PubMed
1233.
Results suggest the involvement of DnaK3 in the translational process on the surface of the thylakoid membrane [DnaK3] (Mus musculus) PubMed
1234.
Pex from cyanobacterium Synechococcus elongatus PCC 7942 has an (alpha+beta) structure with a winged-helix motif and functions as a dimer; the subunit arrangement in the dimer is unique. Pex is a DNA-binding transcription factor[pex protein] (Mus musculus) PubMed
1235.
results suggest that DnaK2 and DnaJ2 are involved in RNA degradation through interaction with RNase E [DnaJ2 & DnaK2] (Mus musculus) PubMed
1236.
in the stress responses of three dnaK homologues (dnaK1, dnaK2, and dnaK3), only the dnaK2 gene was induced [nak1,dnak2, dnak3] (Mus musculus) PubMed
1237.
PratA is a periplasmic tetratricopeptide repeat protein involved in biogenesis of photosystem II in Synechocystis sp. PCC 6803 (Mus musculus) PubMed
1238.
Under salt stress, hspA, groEL2 and dnaK2 were transcriptionally induced and greatly stabilized, indicating a transcriptional and post-transcriptional mechanism of acclimation to salt stress involving these heat-shock genes. [hspA],[groEL2],[dnaK2] (Mus musculus) PubMed
1239.
PixJ1 protein was overexpressed as a fusion with a poly-histidine tag (His-PixJ1); His-PixJ1 showed novel photoreversible conversion between a blue light-absorbing(Pb, lambdaAmax=425-435 nm) and a green light-absorbing form (Pg, lambdaAmax=535 nm) [PixJ1] (Mus musculus) PubMed
1240.
menB and rubA have roles in expression of FX, FA, and FB and plastoquinone or exchanged 9,10-anthraquinone [rubA] (Mus musculus) PubMed
1241.
results suggest that aquaporin-mediated shrinkage of the Synechocystis cells plays an important role in changes of gene expression in response to hyperosmotic stress [Aqpz] (Mus musculus) PubMed
1242.
Hik8 plays an important role in glucose metabolism and is necessary for heterotrophic growth. [Hik8] (Mus musculus) PubMed
1243.
structure analyzed by x-ray diffraction [apocarotenoid-15,15'-oxygenase] (Mus musculus) PubMed
1244.
results indicate that SigE functions in the transcriptional activation of sugar catabolic pathways in Synechocystis sp. PCC 6803 [SigE]. (Mus musculus) PubMed
1245.
FesM, encoding a novel membrane iron-sulfur protein, is essential to cyclic electron flow in the cyanobacterium Synechococcus. (fesM protein) (Mus musculus) PubMed
1246.
the environmental regulation of the Synechocystis sp. PCC 6803 deg genes at the level of transcription and protein structures [degP, depQ, degS] (Mus musculus) PubMed
1247.
PamA has a role in the transcript control of genes for nitrogen and sugar metabolism in Synechocystis sp. PCC 6803 (Mus musculus) PubMed
1248.
Signal transduction protein P(II) is dephosphorylated in Synechocystis sp. strain PCC 6803 by protein phosphatase PphA [PPHA] (Mus musculus) PubMed
1249.
role of cytochrome c6 in reaction mechanism of photosystem I reduction [cytochrome c6] (Mus musculus) PubMed
1250.
characterization and crystal structure of Synechocystis arogenate dehydrogenase (Mus musculus) PubMed
1251.
identification of the gene for monoglucosyldiacylglycerol (MGlcDG) synthase, which catalyzes the first step of galactolipid synthesis in cyanobacteria[MGlcDG synthase] (Mus musculus) PubMed
1252.
The crystal structure of the substrate-free form of PcyA from Synechocystis sp. PCC 6803 at 2.5 A resolution was determined.[PcyA] (Mus musculus) PubMed
1253.
Cytochrome c3 and [NiFe]-hydrogenase are linked to photosystem I to photoproduce hydrogn. [photosystem I] (Mus musculus) PubMed
1254.
Overall, we determined that transcription of the heat-shock genes are regulated to various degrees by SigB, SigE and HrcA. [SigB, SigE] (Mus musculus) PubMed
1255.
PfsR has a critical role in regulation of iron homeostasis and stress response (Mus musculus) PubMed
1256.
SpkA regulates the expression of putative pilA9-pilA10-pilA11-slr2018, pilA5-pilA6, and pilA1-pilA2 operons and is essential for the formation of thick pili.[SpkA] (Mus musculus) PubMed
1257.
Ala69Ser substitution on Synechocystis sp. PCC 6803 hemoglobin resulted in minor structural perturbations, but the response of the holoprotein to temperature-, urea-, and acid-induced denaturation was measurably affected. [Hemoglobin] (Mus musculus) PubMed
1258.
We find that cya1 and sycrp1 mutants are motile and phototactic but are impaired in one particular phase of phototaxis in comparison with wild-type Synechocystis sp. (Mus musculus) PubMed
1259.
PedR (Ssl0564) senses the activity of photosynthetic electron transport to achieve the photon flux density-dependent transcriptional regulation (Mus musculus) PubMed
1260.
Nuclear magnetic resonance (NMR) was used to map the binding sites on Synechocystis ferredoxin for ferredoxin-thioredoxin reductase. (Mus musculus) PubMed
1261.
FutA2 contributes to metal partitioning in the periplasm by sequestering ferric iron (Fe(III)), which limits aberrant Fe(III) associations with vital binding sites for other metals, including copper. (Mus musculus) PubMed
1262.
Results demonstrate that dspA and nblR-like do not exert a major control of phycobilisomes degradation in Synechocystis sp. PCC 6803. [dspA, NblR-like proteins} (Mus musculus) PubMed
1263.
This study identified the factor that binds the HLR1 upstream of the HL-inducible hliB gene in the cyanobacterium Synechocystis PCC 6803 as the RpaB (Slr0947) response regulator.[RpaB hliB proteins] (Mus musculus) PubMed
1264.
REsults describe a beta-1,4-glucanase-like protein (SsGlc) from Synechocystis PCC6803 and suggest that SsGlc functions in salt stress tolerance. (Mus musculus) PubMed
1265.
SigD and SigE interfere with each other's expression. (SigD) (SigE) (Mus musculus) PubMed
1266.
Expression of DnaK3 appears also to be as essential as expression of DnaK2, whereas the dnaK1 gene was deleted without resulting in any distorted phenotype.[DnaK1, DnaK2, DnaK3] (Mus musculus) PubMed
1267.
mutations into SphR show that Gly-225 and Trp-236, which are both conserved in SphR from cyanobacteria, are essential for activation of the Pho regulon under phosphate-limiting conditions.[SphR] (Mus musculus) PubMed
1268.
We analyse the mechanism underlying (GS)glutamine synthetase I reactivation and find that this process involves IF7 and IF17 proteolytic degradation. [GSI, IF7, I17] (Mus musculus) PubMed
1269.
Unique to these ABC zinc transporters, ZnuA has a highly charged and mobile loop that protrudes from the protein in the vicinity of the metal binding site that we had suggested might facilitate zinc acquisition.zua, synechocystis (Mus musculus) PubMed
1270.
The Fe/S protein SufR thus functions both as a transcriptional repressor of the sufBCDS operon and as an autoregulator of sufR.[sufR, sufBCDS] (Mus musculus) PubMed
1271.
This transcription factor, an AbrB-like protein functions as a regulator of hox gene expression. [AbrB] (Mus musculus) PubMed
1272.
There is a reduced level of ferric FutA2 in the periplasm of the DeltafutA1 mutant providing an explanation for its severe iron-uptake phenotype.[FutA2] (Mus musculus) PubMed
1273.
study reports three-dimensional structures of two proteins of previously unknown function, CcmL and OrfA (or CsoS4A), from the two known classes of carboxysomes, at resolutions of 2.4 and 2.15 angstroms [OrfA or CsoS4A] (Mus musculus) PubMed
1274.
Thus, CpcM is the methyltransferase that modifies the amide nitrogen of Asn71/72 of CpcB, ApcB, and ApcF. (Mus musculus) PubMed
1275.
The loss of phycocyanin-lyase function causes pleiotropic effects in Synechocystis sp. PCC 6803.[Phycocyanin lyase] (Mus musculus) PubMed
1276.
The hybrid kinase Sll0043 regulates phototaxis by suppressing the expression of pilA1 biosynthesis and pilT2. [pilA1] (Mus musculus) PubMed
1277.
CcaS phosphorylates CcaR under green light and induces expression of cpcG2, leading to accumulation of CpcG2-phycobilisome as a chromatic acclimation system[CcaS] (Mus musculus) PubMed
1278.
Mutation prqRL17Q changes the specificity of the PrqR repressor protein and thereby affects the regulation of phototaxis at the level of photoperception and signal transduction in cells. (Mus musculus) PubMed
1279.
Psb30 is required for the efficient function of photosystem II complexes, particularly under high irradiance conditions. [Psb30] (Mus musculus) PubMed
1280.
PetC1, PetC2 and PetC3 are Rieske iron-sulfur proteins. PetC1 and PetC2 are Tat substrates and are located in the thylakoid membrane. PetC3 is primarily located in the plasma membrane. [PetC1, PetC2, PetC3] (Mus musculus) PubMed
1281.
substrate specificity stems from faster turnover of GTP, rather than different affinities for GTP and ATP, implying that the specificity-determining interactions are established after the binding step[guanylyl cyclase Cya2] (Mus musculus) PubMed
1282.
RpaB acts as a transcriptional activator for PSI genes. [RpaB] (Mus musculus) PubMed
1283.
Enzymatic and spectroscopic properties of Synechocystis cytochrome bd, were characterized.[Cytochrome bd] (Mus musculus) PubMed
1284.
These results suggested that in contrast to a previous report, the loss of photosynthetic activity may not have been due to the loss of thylakoid membranes, but may have been caused more directly by the loss of Vipp1 in Synechocystis 6803.[Vipp1] (Mus musculus) PubMed
1285.
The authors show that in the absence of MrgA, which is known to be involved in the storage or mobilization of iron, cells can be more easily damaged by exogenous oxidative and light stress.[mrgA] (Mus musculus) PubMed
1286.
The light-harvesting system of the sigBD double mutant does not acclimate normally to higher light intensity. [SigB] (Mus musculus) PubMed
1287.
The presence of the carotenoid carbonyl group that distinguishes echinenone and hydroxyechinenone from zeaxanthin is essential for the OCP activity.[OCP] (Mus musculus) PubMed
1288.
role of NhaS3 in the maintenance of ion homeostasis of H+, Na+, and K+ in supporting the conversion of photosynthetic products and in the supply of energy in the dark[NHAS3] (Mus musculus) PubMed
1289.
The expression of AdhA, an alcohol dehydrogenase, is enhanced upon the exposure of cells to different environmental stresses. AdhA induction is dependent on the Hik34-Rre1 two-component system. New Gene: AdhA (Mus musculus) PubMed
1290.
The Arg7Leu mutation on the alpha-subunit of cyt b559 alters the interaction between the allophycocyanin core complex and PSII reaction centers.[cyt b559] (Mus musculus) PubMed
1291.
Results identify several amino acid residues that are essential for monoglucosyldiacylglycerol synthase activity at both normal growth temperature and high temperature. (Mus musculus) PubMed
1292.
Data found that both SepF and Ftn6 interact physically with FtsZ and that , but not Ftn6, stimulates the formation and/or stability of FtsZ polymers in vitro.[SepF] (Mus musculus) PubMed
1293.
The electrostatic potential of the surface generated by Psb27 amphipathic helices shows a dipolar distribution which fits perfectly into the major PsbO binding site on the photosystem II complex. [Psb27] (Mus musculus) PubMed
1294.
The position of conserved residues on the Psb27 surface suggests conserved functional roles for distinct interconnected features encompassing a P-phi-P loop, a polar patch spanning helices alpha3 and alpha4, and the amino-terminal sequence. [Psb27] (Mus musculus) PubMed
1295.
ZipN interacts with itself and the self-interacting protein Cdv3, and is a central player of divisome assembly in cyanobacteria. [ZipN] (Mus musculus) PubMed
1296.
crystal structure of the full-length HMG-CoA synthase was determined at 2.0-A resolution, representing the first structure of an HMG-CoA synthase from any organism [HMG-CoA synthase strain WCUH29] (Mus musculus) PubMed
1297.
The roles of HtrA-like serine surface proteases, htrA1 and htrA2, in the thermal stress response and and processing and/or degradation of extracellular proteins was investigated (HtrA1 and HtrA2). (Mus musculus) PubMed
1298.
Staphylococcal accessory regulator A (sarA) may play a role in the intrinsic multidrug resistance mechanism of S. aureus (sarA). (Mus musculus) PubMed
1299.
crystal structure of peptide deformylase in complex with actinonin, a naturally occurring antibacterial agent [peptide deformylase] (Mus musculus) PubMed
1300.
Results describe the structures of Aspergillus nidulans and Staphylococcus aureus dehydroquinate synthase (AnDHQS and SaDHQS), and compare ligand-induced conformational changes and mechanisms of domain closure between fungal and bacterial enzymes. (Mus musculus) PubMed
1301.
FhuD1 is a ferric hydroxamate-binding lipoprotein in Staphylococcus aureus (Mus musculus) PubMed
1302.
Bap binds Ca2+ with low affinity and that Ca2+ binding renders the protein noncompetent for biofilm formation and for intercellular adhesion [Bap (biofilm-associated protein)]by Staphylococci isolated from chronic mastitis [Bap strain V329] (Mus musculus) PubMed
1303.
AgrA binds to RNAIII and functions as a response regulator with recognition sites in the promoter regions of RNAIII and the agr locus [AgrA strain DB] (Mus musculus) PubMed
1304.
results indicate that spa expression is controlled by DNA supercoiling and suggest that the Arl sytem is involved in the control of spa expression by DNA supercoiling [spa, ArlS, ArlR] (Mus musculus) PubMed
1305.
a key finding of this study is that Staphylococcus aureus pantothenate kinase (CoaA) differs from all described previously pantothenate kinases in that it is refractory to feedback inhibition by CoA and/or its thioesters [CoaA] (Mus musculus) PubMed
1306.
MgrA overexpression and promoter region mutations result in a reduction in NorA expression [mgrA AND norA] (Mus musculus) PubMed
1307.
Detection of the antiseptic- and disinfectant-resistance genes qacA and qacB in methicillin-resistant S. aureus isolated during MRSA surveillance in a single hospital.[qacA, qacB] (Mus musculus) PubMed
1308.
staphostatin B structure compared to standard mechanism serine protease inhibitors [staphostatin B] (Mus musculus) PubMed
1309.
PBP2 recruited to the division site by binding to its transpeptidation substrate, which is localized at that place [PBP2, strain RN4220] (Mus musculus) PubMed
1310.
spa repression occurs not only at the transcriptional level but also by RNAIII-mediated inhibition of translation and degradation of the stable spa mRNA by the double-strand-specific endoribonuclease III (RNase III) [spa & endoribonuclease III & RNAIII] (Mus musculus) PubMed
1311.
The coordination of pbp2 with pbp4 and pbp2a (in MeSH) in ceftizoxime resistance and cell wall cross-linking.[pbp2a] (Mus musculus) PubMed
1312.
studies here have defined the nature of interaction of mgrA with other regulators such as agr, sarS, and sarT and its role in regulating hla and spa transcription within the virulence regulatory network of S. aureus[MgrA] (Mus musculus) PubMed
1313.
PIA expression is dependent on the genetic background of the strain as well as on strong inducing conditions in device-related infection model, such as those dominating in vivo. [PIA] (Mus musculus) PubMed
1314.
The regulatory role of MgrA in the expression of NorB and Tet38, two drug efflux pumps in S. aureus [MgrA, NorB, Tet38] (Mus musculus) PubMed
1315.
demonstrated that a putative glycoprotease (Gcp) is required for staphylococcal growth [gcp] (Mus musculus) PubMed
1316.
data indicates that ClpYQ plays only a secondary role in the degradation of non-native proteins in S. aureus [ClpY, ClpQ] (Mus musculus) PubMed
1317.
results show that Pls is a virulence factor for septic arthritis and sepsis [Pls] (Mus musculus) PubMed
1318.
cloning and identification of the gene, azo1, encoding a novel aerobic tetrameric FMN-dependent azoreductase [Azo1] (Mus musculus) PubMed
1319.
results indicate that cidC is involved in the generation of acetic acid that contributes to the cell death and lysis that occurs in high-glucose stationary phase cultures [cidC, pyruvate oxidase] (Mus musculus) PubMed
1320.
identification of sae as an important regulator of the staphylococcal adhesins Eap and Emp, which is capable of modulating their expression under different environmental conditions [sae, Eap, Emp] (Mus musculus) PubMed
1321.
Structural model and substrate specificity of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus (FAbH). (Mus musculus) PubMed
1322.
SEG and SEI co-express, differently interact with MHC class II, stimulate different subsets of T-cells, which indicate complementary superantigenic activity and suggest an important advantage to staphylococcal strains in producing them both.(SEG)(SEI) (Mus musculus) PubMed
1323.
ClfA promotes platelet activation in fibrinogen dependent and independent pathways with the latter requiring IGG and complement deposition [ClfA, clumping factor A] (Mus musculus) PubMed
1324.
the cidR gene product functions as a transcriptional activator of cidABC transcription in response to acetic acid accumulation in the growth medium [CidR] (Mus musculus) PubMed
1325.
strains carrying seb and selp produced SEB but not SElP, suggesting the inactivation of the selp locus in S. aureus strains with a particular se gene constitution (SElP = staphylococcal enterotoxin-like toxin P) (Mus musculus) PubMed
1326.
ClfA(221-550) is a fibrinogen-binding segment of Staphylococcus aureus clumping factor A that disrupts fibrinogen function [from isolate 30326] (Mus musculus) PubMed
1327.
role of penicillin Binding protein 2a in oxacillin resistance, and discovery of functionally impaired form of PBP2a with a novel amino acid substitution [PBP2a] (Mus musculus) PubMed
1328.
roles in copper homeostasis and oxidative stress response [mco, multicopper oxidase] (Mus musculus) PubMed
1329.
TRAP is a master regulator of staphylococcal pathogenesis.(TRAP) (Mus musculus) PubMed
1330.
DsbA is a membrane localised lipoprotein, supporting a role in disulfide bond formation. The persistence of the protein throughout the growth cycle despite its predominant transcription during exponential growth phase suggested a long half-life[DsbA] (Mus musculus) PubMed
1331.
role of the N terminus in the assembly of alpha-hemolysin [alpha-hemolysin] (Mus musculus) PubMed
1332.
purification and characterization of a 32 kDa N-acetylmuramyl-L-alanine amidase designated Sle1; findings suggest Sle1 is involved in cell separation [Sle1] (Mus musculus) PubMed
1333.
results demonstrated that the YhcSR regulatory system is indispensable for S. aureus growth in culture [YhcS, YhcR] (Mus musculus) PubMed
1334.
crystal structure in three crystal forms at different pH values [LytM] (Mus musculus) PubMed
1335.
dltA and mprF mutations in Staphylococcus aureus increased in vitro susceptibility to platelet microbicidal protein 1 and significantly attenuated virulence. (dltA)(mprF) (Mus musculus) PubMed
1336.
To assess the roles of ClpX and ClpP within the sar/agr regulatory network, deletions in clpX and clpP were combined with mutations in these genes. (ClpX) (ClpP) (Mus musculus) PubMed
1337.
SigB regulates transcription of virulence factors in SCVs (Staphylococus aureus small-colony variant) from cystic fibrosis patients [SigB] (Mus musculus) PubMed
1338.
Data suggest that the fibrinogen/fibronectin-binding proteins FnBPA and FnBPB are major platelet-activating factors on the surface of S. aureus, and act through FcgammaRIIa and GPIIb/IIIa [FnBPA, FnBPB]. (Mus musculus) PubMed
1339.
Data describe the contribution that individual metal ligands of the alpha5 sensing site of S. aureus CzrA make to metal ion binding affinity, coordination geometry, and allosteric negative regulation of DNA operator/promoter region binding (Mus musculus) PubMed
1340.
cocrystal structure reveals the basis for both sequence and structure specificity in the interactions of TadA with RNA, and it additionally provides insight into the active site architecture that promotes efficient hydrolytic deamination [TadA] (Mus musculus) PubMed
1341.
Small colony variants (SCVs) of Staphylococcus aureus as well as hemB- and menD-deficient mutants of S. aureus are greatly reduced in virulence in the C. elegans infection model. [HemB, MenD] (Mus musculus) PubMed
1342.
first report of a temperature-sensitive dnaA mutant in S. aureus, and the results show that DnaA is required for the initiation of chromosomal replication and for the regulation of synchrony in the bacterial cells [DnaA] (Mus musculus) PubMed
1343.
2.6 A-resolution x-ray crystal structure of the dimeric winged helix SarA protein was reported. (Mus musculus) PubMed
1344.
findings support the conclusion that FhuC functions with FhuB, FhuG, and FhuD1 or FhuD2 to transport iron(III)-hydroxamates and is the "genetically unlinked" ABC-ATPase that functions with SirA, SirB, and SirC to transport iron(III)-staphylobactin [FhuC] (Mus musculus) PubMed
1345.
Derepression of PerR by HOCl is dependent on the level of SOD and protects exponentially arrested cells against HOCl stress.[PerR, SOD] (Mus musculus) PubMed
1346.
in spite of the preferential location of the binding epitopes within triple helical regions in some collagens there is a striking specificity of Eap binding to different collagen types [Eap] (Mus musculus) PubMed
1347.
Complementation experiments with sigB on a plasmid reduced expression of proteases and alpha-hemolysin dramatically, indicating that the high production of these exoproteins was associated with sigmaB deficiency. [SigB] (Mus musculus) PubMed
1348.
role of the conserved Glu100 of S. aureus MGT (equivalent to the proposed catalytic Glu233 of E. coli PBP1b) by site-directed mutagenesis [monofunctional glycosyltransferase] (Mus musculus) PubMed
1349.
observations suggest that the role of murF exceeds its primary function in peptidoglycan biosynthesis and may also be involved in the control of cell division (Mus musculus) PubMed
1350.
The role of SarA in the regulation of virulence factor expression in S. aureus is reported.[SarA] (Mus musculus) PubMed
1351.
The dimeric repressor MecI regulates the mecA gene that encodes the penicillin-binding protein PBP-2a in methicillin-resistant Staphylococcus aureus(MecI) (Mus musculus) PubMed
1352.
MoaA binds 5'-GTP with high affinity and interacts through its C-terminal [4Fe-4S] cluster with the guanine N1 and N2 atoms, in a yet uncharacterized binding mode [MoaA] (Mus musculus) PubMed
1353.
ClfA inhibited phagocytosis in the absence of fibrinogen, and showed enhanced inhibition in the presence of fibrinogen. (Mus musculus) PubMed
1354.
Data show that SarR (a member of the SarA protein family) in part regulates agr expression by direct binding to the agr intergenic promoter region as determined by gel shift and DNase I footprinting assays [SarR]. (Mus musculus) PubMed
1355.
results suggest that LukM/F'-PV may constitute a particular virulence attribute of mastitis-causing S. aureus strains [LukM, LukF'-PV] (Mus musculus) PubMed
1356.
Apart from an apparent direct positive effect of mgrA on sspA & aur transcription, these genes were mainly controlled through repression by sarA & rot, which seemed to occur via binding of SarA & Rot to the aur & sspA promoters, respectively[sarA, rot] (Mus musculus) PubMed
1357.
assembly of LukS and LukF into the pore-complex occurs in lipid rafts in human polymorphonuclear leukocytes and that LukF can bind to LukS, which had already bound to lipid rafts, to assemble into hetero-oligomers [LukS and LukF] (Mus musculus) PubMed
1358.
it is concluded that expression of the Cfr rRNA methyltransferase confers a PhLOPSA resistance phenotype (resistance to five chemically distinct classes of antimicrobials: Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A [Cfr] (Mus musculus) PubMed
1359.
Our results indicate that activation of the SaeRS system may be required for S. aureus to adhere to and invade epithelial cells. [SaeR, SaeS] (Mus musculus) PubMed
1360.
examined the potential of the YjeQ protein as a virulence determinant [YjeQ] (Mus musculus) PubMed
1361.
role in Staphylococcus aureus fitness and resistance to antioxidants and neutrophil killing [staphyloxanthin] (Mus musculus) PubMed
1362.
RNAIII regulates the synthesis of Rot, by blocking its translation; it is proposed that the RNAIII-rot mRNA interaction plays a key role in agr regulation of staphylococcal virulence [rot] (Mus musculus) PubMed
1363.
findings show that the vraS/vraR regulatory system plays a crucial role in allowing MRSA to respond to beta-lactams by regulation of a gene target other than the known effectors of methicillin resistance [VraS, VraR] (Mus musculus) PubMed
1364.
3.0 A crystal structure of a bacterial ABC transporter (Sav1866) from Staphylococcus aureus [Sav1866] (Mus musculus) PubMed
1365.
The study reveals that in Staphylococcus aureus, MgrA adopts a similar mechanism but uses it to globally regulate different defensive pathways. (Mus musculus) PubMed
1366.
crystal structure of S. aureus CoADR has been solved using multiwavelength anomalous dispersion data and refined at a resolution of 1.54 A [coenzyme A-disulfide reductase] (Mus musculus) PubMed
1367.
cells surviving an attack by alpha toxin can be induced to proliferate via recruitment of an EGFR-dependent signalling pathway (alpha-toxin) (Mus musculus) PubMed
1368.
results indicate that exported alpha-toxin inhibits the adhesion and internalization of S. aureus by interfering with integrin-mediated pathogen-host cell interactions (S. aureus WCUH29 alpha-tox; hla gene) (Mus musculus) PubMed
1369.
results indicate that, in contrast to NCTC 8325 derivatives, agr plays a limited role in overall regulation of gene expression in UAMS-1, when compared with sarA [agr, sarA] (Mus musculus) PubMed
1370.
Collectively, the results suggest that arlR positively regulates capsule production at the transcriptional level primarily through an mgrA-dependent pathway.[arlR, mgrA] (Mus musculus) PubMed
1371.
The structures of unliganded monophosphate kinase (GMK) and GMK complexed with GMP at 1.9 A resolution (GMK). (Mus musculus) PubMed
1372.
S. aureus FnBPA produces attachment sites that promote bacterial movements but subvert actin- and Rab5 reorganization during invasion.[FnBPA] (Mus musculus) PubMed
1373.
IsdB-mediated scavenging of iron from hemoglobin represents an important virulence strategy for S. aureus replication in host tissues and for the establishment of persistent staphylococcal infections. [IsdB] (Mus musculus) PubMed
1374.
Regulation of Staphylococcus aureus alpha-toxin gene (hla) expression by agr, sarA, and sae [hla] (Mus musculus) PubMed
1375.
SrrAB regulates RNAIII, tst, spa, icaR, and icaA in a clinical isolate of S. aureus, MN8 (SrrA and SrrB). (Mus musculus) PubMed
1376.
Three genes in glycolipid synthesis and lipotheichoic acid anchoring were identified: alpha-phosphoglucomutase (PgcA) and UTP:alpha-glucose 1-phosphate uridyltransferase (GtaB)and LtaA (lipoteichoic acid protein A), [PgcA, GtaB, LtaA] (Mus musculus) PubMed
1377.
findings show that Panton-Valentine leukocidin is sufficient to cause pneumonia & that the expression of this leukotoxin induces global changes in transcriptional levels of genes encoding secreted & cell wall-anchored staphylococcal proteins [LukS,LukF] (Mus musculus) PubMed
1378.
The study suggests that Fibronectin binding protein A (FnBPA) binds to fibrinogen and elastin in a similar manner, amino acid sequence divergence of 26.5% occurred between the A domains of FnBPA from strains 8325-4 and P1. [FnBPA protein] (Mus musculus) PubMed
1379.
crystal structure of Sav1866 in complex with adenosine-5'-(beta,gamma-imido)triphosphate (AMP-PNP) at 3.4A resolution and comparison with the previously determined structure of Sav1866 with bound ADP (Mus musculus) PubMed
1380.
results support the previous report that isaA expression is regulated by YycF, and also suggest that IsaA is probably involved in bacterial proliferation by residing on the cell wall [IsaA] (Mus musculus) PubMed
1381.
menstrual toxic shock syndrome patients may be incapable of generating TSST-1 neutralizing antibodies (Mus musculus) PubMed
1382.
2.8 angstrom structure of penicillin binding protein 2, a bifunctional cell-wall cross-linking enzyme, including its transpeptidase and GT domains, both unliganded and complexed with the substrate analog moenomycin [PBP2] (Mus musculus) PubMed
1383.
Interaction of alpha-toxin with alpha5beta1-integrin and overproduction of TNF-alpha may contribute to destruction of epithelial cells during S. aureus infection. (Mus musculus) PubMed
1384.
The active site proline in thioredoxin determines the driving potential for substrate reduction (Sa_Trx) (Mus musculus) PubMed
1385.
Study shows that protein A, the ligand of immunoglobulin, is unevenly distributed over the staphylococcal surface; upon removal with trypsin, newly synthesized polypeptide is deposited at two to four discrete foci. [protein A] (Mus musculus) PubMed
1386.
Transient nature of MupA polymorphism accounts for transient loss of high level mupirocin resistance. [MupA] (Mus musculus) PubMed
1387.
The data indicate that the expression of rot transcription is significantly repressed only by SarA. [rot] (Mus musculus) PubMed
1388.
the antithrombotic effect of ClfA221-550 may result from the blockade of fibrinogen gamma chain C-terminal functions, in mediating platelet aggregation and fibrin clot formation.[Clumping factor A, Staphylococcus aureus} (Mus musculus) PubMed
1389.
GraRS, the 2 component regulatory system regulates vancomycin intermediate resistance phenotype by interactions with VraFG ABC transporter. [GraR, GraS] (Mus musculus) PubMed
1390.
The absence of Bap correlated with increased adherence to fibrinogen and fibronectin.[Bap protein] (Mus musculus) PubMed
1391.
Constructed tatC-deficient mutants from distinct parent strains showed the same patterns of exoproteins compared with those of parent strains; it seems that the Tat pathway does not play a major role in the secretion system of S. aureus.[tatC] (Mus musculus) PubMed
1392.
Linezolid resistance in a methicillin-resistant Staphylococcus aureus hospital strain from Colombia is determined by the cfr gene whose product, Cfr methyltransferase, modifies adenosine at position 2503 in 23S rRNA in the large ribosomal subunit. [Cfr] (Mus musculus) PubMed
1393.
NMR solution structure of MecI complexed to a operator sequence provides insights for the repression and induction mechanisms of bacterial resistance to beta-lactams (MecI). (Mus musculus) PubMed
1394.
Crystal structures of Mevalonate diphosphate decarboxylase (MDD) from T. brucei (TbMDD, at 1.8 A resolution) and S. aureus (SaMDD, each diffracting to 2.3 A resolution) have been determined[mevalonate diphosphate decarboxylase ] (Mus musculus) PubMed
1395.
the monomer orthorhombic Sau3AI/E64A crystal is in space group C2221 with unit cell parameters (69.44, 197.60, 191.46, 90, 90, 90) and contains two molecules in one asymmetric unit[Sau3AI endonuclease] (Mus musculus) PubMed
1396.
Data supports a catalytic mechanism in which the reduced flavin coenzyme mediates a single electron transfer to and from the IPP substrate during catalysis by type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IDI-2). (Mus musculus) PubMed
1397.
Cloning and purification of the two known S. aureus signal peptidases, SpsA and SpsB, demonstrated that only SpsB catalysed type I signal peptidase activity in vitro. (Mus musculus) PubMed
1398.
The ypfP gene responsible for biosynthesis of a glycolipid found in LTA was deleted in Staphylococcus aureus SA113, causing 87% reduction of the LTA content.[ypfP, autolysin] (Mus musculus) PubMed
1399.
An isaA sceD mutant is attenuated for virulence, while SceD is essential for nasal colonization in cotton rats, thus demonstrating the importance of cell wall dynamics in host-pathogen interactions.[isaA, sceD] (Mus musculus) PubMed
1400.
results demonstrate that SrrAB is a major activator of ica expression and polysaccharide intercellular adhesin production in anaerobic environments, where it contributes to the protection of S. aureus against non-oxidative defence mechanisms [SrrA, SrrB] (Mus musculus) PubMed
1401.
As the length of the ClfA repeat region increased, binding of acapsular S. aureus to fibrinogen-coated microtiter plates was enhanced; by contrast, encapsulated S. aureus expressing the full-length ClfA were poorly adherent.[ClfA] (Mus musculus) PubMed
1402.
This study showed that WalKR positively controls autolytic activity.[WalK; WalkR] (Mus musculus) PubMed
1403.
the three-dimensional structure of the complex of SSL7 with Fc of human IgA1 at 3.2 A resolution (SSL7). (Mus musculus) PubMed
1404.
findings show that S aureus products have various effects on mucosal tissues: surface protein A induces mast cell degranulation, whereas enterotoxin B induces the release of cytokines, with a T(H)2-skewed pattern in nasal polyps.[SEB, protein A] (Mus musculus) PubMed
1405.
Affinity purification of proteins binding to the rot promoter fragment, followed by N-terminal protein sequencing, identified the SarA and SarR proteins.[SarA and SarR in strain GP269] (Mus musculus) PubMed
1406.
The effects of ceramide incorporation in supported bilayers prepared from ternary lipid mixtures which have small nanoscale domains have been examined using atomic force and fluorescence microscopy.[SMase] (Mus musculus) PubMed
1407.
MenB consists of 2 subunits & a crystallographic threefold axis of symmetry generates a hexamer. MenB displays crotonase-family fold with distinct N- & C-terminal domains & a flexible segment of structure around the active site.[MenB] (Mus musculus) PubMed
1408.
SaDsbA crystals diffract to a resolution limit of 2.1 A and belong to the hexagonal space group P6(5) or P6(1), with unit-cell parameters a = b = 72.1, c = 92.1 A and one molecule in the asymmetric unit (64% solvent content)[DsbA] (Mus musculus) PubMed
1409.
The expression of copA and copZ was inducible by copper and to some extent by ferric and lead ions. The cysteine residues in the CXXC metal-binding motif in CopA are involved in copper binding and play an important role in copper transport. [CopA, CopZ] (Mus musculus) PubMed
1410.
fibrinogen and IgG binding to ClfA is essential for aggregate formation under arterial shear conditions and may explain why S. aureus is the major cause of infective endocarditis [C1fA] (Mus musculus) PubMed
1411.
This strain is the first clinical isolate of MRSA for which the genetic base for high-level resistance has been clarified. It is connected to a LytH mutation caused by IS1182 insertion. [LytH] (Mus musculus) PubMed
1412.
These results suggest that His343 of S. aureus MurC is essential for high-affinity binding to L-alanine both in vitro and in vivo and provide experimental evidence supporting the structural information of MurC ligase.[MurC] (Mus musculus) PubMed
1413.
The crystal structures of non-thiocarboxylated MPT synthase from Staphylococcus aureus in its apo form and in complex with precursor Z, is presented.[MPT synthase] (Mus musculus) PubMed
1414.
Collectively, the data implicated the importance of sae in the rot-mediated repression of hla in S. aureus. [rot, hla in strain RN4220] (Mus musculus) PubMed
1415.
Mutants resulting from an rplB-to-rplV gene conversion-like event is specific to selection of telithromycin resistance in staphylococcus aureus. [rplB, rplV] (Mus musculus) PubMed
1416.
In Staphylococcus aureus V8 strain, data showed that glutamyl endopeptidase I (GluV8) Ser237 was essential for proteolytic activity, and Val69 was indispensable for the cleavage by thermolysin and was involved in the proteolytic reaction itself [GluV8] (Mus musculus) PubMed
1417.
The spontaneous reversible unfolding and refolding of staphylococcal nuclease under native conditions was studied by a kinetic native-state hydrogen exchange (HX) method.[SNase] (Mus musculus) PubMed
1418.
This study shows that this variation of biofilm formation in S. aureus is deduced by the role of sigB, not agr and sarA. [SigB] (Mus musculus) PubMed
1419.
determineation of the crystal structures of S. aureus dehydrosqualene synthase (CrtM) at 1.58 angstrom resolution; structural similarity to human squalene synthase found [dehydrosqualene synthase] (Mus musculus) PubMed
1420.
The crystal structures at 2.8-A resolution of full-length PC from Staphylococcus aureus and the C-terminal region (missing only the BC domain) of human PC, is reported.[Pyruvate carboxylase] (Mus musculus) PubMed
1421.
The signal transduction mechanism of the VraSR system, is reported.[VraR, VraS] (Mus musculus) PubMed
1422.
triclosan, 5-ethyl-2-phenoxyphenol (EPP), and 5-chloro-2-phenoxyphenol (CPP) are all nanomolar slow-onset inhibitors of saFabI[FabI] (Mus musculus) PubMed
1423.
Deletion of ccpA, coding for the catabolite control protein A (CcpA), abolished the capacity of SA113 to form a biofilm under static and flow conditions, while still allowing primary attachment to polystyrene surfaces.[CcpA in strain SA113] (Mus musculus) PubMed
1424.
data identify a novel S. aureus biofilm phenotype promoted by FnBPA and FnBPB which is apparently independent of the known ligand-binding activities of these proteins[FnBPA, FnBPB] (Mus musculus) PubMed
1425.
model contradicts the previously proposed mechanism of binding predicted by the x-ray crystal structure of SrtA[ sortase A] (Mus musculus) PubMed
1426.
Two mutations were identified in katA from S. aureus UCN61,a methicillin-susceptible catalase-negative strain isolated from an arterial leg ulcer, including one leading to a substitution of key histidine 58 by a tyrosine. [katA] (Mus musculus) PubMed
1427.
Results describe SplB protease catalytic activity and reveal that the enzyme possesses exquisite specificity and only cleaves efficiently after the sequence Trp-Glu-Leu-Gln. (Mus musculus) PubMed
1428.
Nuclease A [nuc1] and thermonuclease [nuc2] are two thermostable nucleases, coesiting and encoded by two different genes. [nuc1, nuc2] (Mus musculus) PubMed
1429.
findings show that graRS deletion considerably alters bacterial surface charge, increases susceptibility to killing by human neutrophils or the defense peptide LL-37 & attenuates virulence of S. aureus in a mouse infection model [GraR, GraS] (Mus musculus) PubMed
1430.
The femA regulating gene probably lies in the 250 bp upstream sequence in methicillin-resistant Staphylococcus aureus and high-level expression is essential for high-level methicillin resistance. (Mus musculus) PubMed
1431.
The crystal structures of the phosphorylated and unphosphorylated states of the tyrosine kinase CapB together with the activator domain of its cognate transmembrane modulator CapA (CapB). (Mus musculus) PubMed
1432.
We were able to create mutants in either of the putative ribitol phosphate polymerases (encoded by tarK and tarL) without affecting teichoic acid levels in the S. aureus cell wall.[TarK and TarL in strain RN4220] (Mus musculus) PubMed
1433.
Staphylococcal accessory regulator (sarR) acts as a stimulator of aur (aureolysin) and sspA (serine protease) transcription, and does not require sarA [sarR, aur, sspA] (Mus musculus) PubMed
1434.
there were no differences in enterotoxin genes between S. aureus strains isolated from controls compared with nasal polyposis patients. (Mus musculus) PubMed
1435.
Two distinctive features of DkgB are a structural Mg2+ site and an associated Asp*water*Mg2+ network that extends toward the active site locale (DgkB). (Mus musculus) PubMed
1436.
S. aureus differentially regulates IsdG and IsdI in response to alterations in iron and haem availability during infection. [IsdI, IsdG] (Mus musculus) PubMed
1437.
analysis of a heme-binding mechanism for IsdH-NEAT3 that involves multimerization [IsdH] (Mus musculus) PubMed
1438.
the overexpression, purification, and functional reconstitution of Sav1866 are described in detail. (Mus musculus) PubMed
1439.
MgrA regulates virulence factors important for establishment and progression of septic arthritis and sepsis. [MgrA] (Mus musculus) PubMed
1440.
two novel genes coding for two superantigens, staphylococcal enterotoxins S and T (SES and SET), were identified (Mus musculus) PubMed
1441.
The findings indicate that NorB can facilitate bacterial survival when they are overexpressed in a staphylococcal abscess and may contribute to the relative resistance of abscesses to antimicrobial therapy. New Gene: NorB (Mus musculus) PubMed
1442.
The strains belonging to coaulase gene restriction fragment length polymorphism pattern L5 and L1 appeared to be the major types of methicillin-resistant Staphylococcus aureus isolasted from bacteremia(Coagulase). (Mus musculus) PubMed
1443.
We show that colonizing isolates of S. aureus can be agr defective and that heterogeneous mixutres of agr positive and afr defective organisms may be present. [Agr] (Mus musculus) PubMed
1444.
TCR binding affinity of SEC2 could be altered by substituting the AAs at position 20 & 22 to increase its superantigen activity & antitumor response. SEC2 T20L/G22E had more of these activities without increased vomiting or fever[SEC2] (Mus musculus) PubMed
1445.
The ABC proteins VgaAv and VgaA were found to be responsible for the reduced susceptibility to pleuromutilins exhibited by these six isolates. [VgaA, VgaAv] (Mus musculus) PubMed
1446.
Results show that the inability of a sarA mutant to repress production of extracellular nuclease and multiple proteases have independent but cumulative effects that contribute to the biofilm-deficient phenotype of an S. aureus sarA mutant [sarA]. (Mus musculus) PubMed
1447.
Low concentrations of Hla change calcium signalling by accelerating pump-driven extrusion of Ca(2+) ions.[Hemolysin A] (Mus musculus) PubMed
1448.
The authors isolated an inhibitor of IL-8 production from the supernatant and identified it as staphylococcal beta-hemolysin.[beta-hemolysin in strain A17] (Mus musculus) PubMed
1449.
Agr controls biofilm formation in most of the clinical isolates tested. [agr] (Mus musculus) PubMed
1450.
The main aim of this study was to evaluate the influence of SigB activity on the fibronectin-binding ability of S. aureus in prototype and cystic fibrosis small-colony variants backgrounds.(SigB) (Mus musculus) PubMed
1451.
TrmE from Staphylococcus aureus was overexpressed in Escherichia coli. The enzyme was found to crystallize at 295 K when ammonium sulfate was used as a precipitant. X-ray diffraction data were collected to 2.9 A resolution (Mus musculus) PubMed
1452.
The relationship between egc1, egc2, egc3, agr, and enterotoxins and classification of Staphylococcus aureus from humans and animals is described.[egc1; egc2; egc3; agr] (Mus musculus) PubMed
1453.
The msa gene plays an important role in biofilm development which is likely due to its role in modulating the expression of sarA (Mus musculus) PubMed
1454.
These results demonstrate that LukF caused the activation of BM-DCs by triggering a TLR4-dependent signaling pathway and suggests that Luk may affect the host inflammatory response as well as show a cytolytic effect on leukocytes.[LukF] (Mus musculus) PubMed
1455.
DNA-binding data show that MepR uses a dual regulatory binding mode as the repressor binds the mepA operator as a dimer of dimers, but binds the mepR operator as a single dimer "MepR". (Mus musculus) PubMed
1456.
These results suggest that certain noncognate AIPs stabilize an inhibitory receptor conformation that may be a critical feature of the ligand-receptor interaction not initially appreciated in previous analyses of agr inhibition.[AgrC] (Mus musculus) PubMed
1457.
Sigb activity is necessary for biofilm formation which is regulated by protease and agr activity. (Mus musculus) PubMed
1458.
S. aureus Serine/threonine kinase (STK)- and phosphatse (STP)-mediated reversible phosphorylation reactions play a critical role in proper cell wall architecture, and thus the modulation of antimicrobial resistance, in S. aureus. [STK, STP] (Mus musculus) PubMed
1459.
CodY in S. aureus not only acts as a repressor for genes involved in nitrogen metabolism but also contributes to virulence gene regulation by supporting as well as substituting for agr function.[CodY] (Mus musculus) PubMed
1460.
This work identifies Asn-108 as a key residue in the translocation pathway of SdcS, accessible in different states from both sides of the membrane.[SdcS] (Mus musculus) PubMed
1461.
TSST-1 production is not directly associated with the agr structure. [tst, agr] (Mus musculus) PubMed
1462.
Carriage of both fnbA and fnbB and growth at 37 degrees C promote MRSA biofilm development, further supporting a role for the FnBPA and FnBPB surface proteins in the pathogenesis of MRSA device-related infections [fnbA; fnbB] (Mus musculus) PubMed
1463.
The role of each metal binding site of CadC was investigated by mutagenesis.[CadC] (Mus musculus) PubMed
1464.
levels of sodM and sodA transcription, in particular the sodM transcript, are markedly enhanced in the sarA mutant among the tested sarA family mutants [SodM, sodA, SarA] (Mus musculus) PubMed
1465.
NtrA is a bifunctional enzyme that exhibits nitroreductase and GSNO reductase activity. New Gene: NtrA (Mus musculus) PubMed
1466.
Fusidic acid resistance determinants in bacteremia isolates belonged to mutations in FusA, FusB, and FusC. [FusA, FusB, FusC] (Mus musculus) PubMed
1467.
murA and murZ UDP-N-acetylglucosamine enolpyruvyl transferases catalyze the first step of peptidoglycan biosynthesis. MurA appears to be the primary enzyme utilized. [MurA; MurZ] (Mus musculus) PubMed
1468.
The authors show that inactivation of the staphylococcal accessory gene regulator sarA leads to dramatic reductions in vancomycin and ciprofloxacin resistance in vancomycin-intermediate and ciprofloxacin-resistant strains of S. aureus. (Mus musculus) PubMed
1469.
crystal structure of human C3b in the presence of a recombinant form of staphylococcal complement-inhibitor protein [scn] (Mus musculus) PubMed
1470.
Catalase protects intracellularly survived bacteria by destroying H2O2 produced by the murine peritoneal macrophages. [catalase] (Mus musculus) PubMed
1471.
MsrR is therefore likely to play a role in cell envelope maintenance, cell separation, and pathogenicity of S. aureus. [MsrR] (Mus musculus) PubMed
1472.
Support is presented for alpha1 as a dimerization interface in phosphorylated VraR, whereas protein-protein interactions for nonphosphorylated VraR are impeded by extensive disorder in this region.[VraR] (Mus musculus) PubMed
1473.
we show that Staphylococcus aureus contains two YoeB homologues, both of which function as ribosome-dependent mRNA interferases to inhibit translation initiation in a manner identical to that of YoeB-ec from Escherichia coli. [YoeB-sa1, YoeB-sa2] (Mus musculus) PubMed
1474.
Crystal structures of SarZ showed that Cys(13) sulfenic acid with an external thiol leads to formation of a mixed disulfide bond. [SarZ] (Mus musculus) PubMed
1475.
SEA is more potent than SEG in inducing the early transcriptional response of human leukocytes. [SEA, SEG] (Mus musculus) PubMed
1476.
Essentially complete backbone and stereospecific methyl group resonance assignments for apo-, Zn2 and a 42 kDa apo-CzrA-DNA complex. (CzrA protein) (Mus musculus) PubMed
1477.
investigated whether mupirocin influences This study evaluated the expression of the ileS-2 gene responsible for high-level mupirocin resistance in S. aureus. (Mus musculus) PubMed
1478.
crystal structure of a carboxy-terminal truncation mutant (Delta95-120) of MscL from Staphylococcus aureus (SaMscL(CDelta26)) at 3.8 A resolution [MscL] (Mus musculus) PubMed
1479.
Study reports the solution quaternary structure of homodimeric CzrA bound to a palindromic 28-bp czr operator, a structure that provides an opportunity to compare the two allosteric "end" states of an ArsR family sensor.[CzrA] (Mus musculus) PubMed
1480.
analysis of exchange of bound ADP on the Staphylococcus aureus replication initiation protein DnaA [DnaA strain RN4220, N18 or NM1003] (Mus musculus) PubMed
1481.
Three residue changes, T101A, V107S, I116S, are sufficient to convert the autoinducing peptide-recognizing specificity from AgrC-IV to AgrC-I.[AgrC] (Mus musculus) PubMed
1482.
important role played by SarA in modulating expression of trxB involved in oxidative stress resistance in S. aureus[SarA and trxB, strain not found in entrez] (Mus musculus) PubMed
1483.
Suggest that OpuC is a TRAP binding protein that acts as a transporter and also plays a role in S. aureus pathogenesis. (Mus musculus) PubMed
1484.
TRAP plays a role in stress response in Staphylococcus aureus. (Mus musculus) PubMed
1485.
Description of a new group of variants of the Staphylococcus aureus elastin-binding protein that lacks an entire DNA segment of 180 bp. (Mus musculus) PubMed
1486.
Panton-Valentine leukocidin gene detected in Staphylococcus aureus strain isolated from a knee arthroprosthesis infection. (Mus musculus) PubMed
1487.
cysteine protease (Ecp) and a downstream gene coding for a putative inhibitor of the protease form an operon which resembles that of staphopain A in S. aureus. The protease was detected on the cell surface and culture media during growth [Ecp] (Mus musculus) PubMed
1488.
PIA expression elevated and less vulnerable to environmental conditions than in Staph aureus in device-realated infection model [PIA]. (Mus musculus) PubMed
1489.
stability of established biofilms depends on sigma(B) activity,however, the slow decay of biofilms under conditions of nutrient limitation reveal its use as an energy-storage molecule to be unlikely. [SigB] (Mus musculus) PubMed
1490.
Disrupting the hemB biosynthetic gene in S. epidermidis resulted in an small-colony variant (SCV) phenotype.[hemB] (Mus musculus) PubMed
1491.
The production of polysaccharide intercellular adhesin (PIA) in Staphylococcus epidermidis is regulated indepently by both sigma B and staphylococcal accessory regulator A (SarA). [polysaccharide intercellular adhesin, sigmaB, sarA] (Mus musculus) PubMed
1492.
The smallest deletion 10-bp long conferring constitutive resistance in the translational attenuator of erm(A) in a naturally occurring S. epidermidis strain of human origin. (Mus musculus) PubMed
1493.
clpP influenced initial attachment of bacteria on the plastic surface, the first step of biofilm formation.[ClpP] (Mus musculus) PubMed
1494.
Result suggest that a 28 bp core segment of the ica operator is implicated in the cooperative binding of two IcaR dimers on opposite sides of the duplex DNA (IcaR). (Mus musculus) PubMed
1495.
SdrG is expressed early during infection in response to specific host environmental cues present in the bloodstream. [SdrG] (Mus musculus) PubMed
1496.
RecA is involved in genetic deletions and rearrangement of the icaADBC operon of Staphylococcus epidermidis.[recA] (Mus musculus) PubMed
1497.
Therefore, GdpS affects biofilm formation through a novel c-di-GMP-independent mechanism involving increased icaADBC mRNA levels and exopolysaccharide biosynthesis.[GdpS in strain CSF41498] (Mus musculus) PubMed
1498.
study investigated maturation processing of native GluSE and that heterologously expressed in Escherichia coli[GluSE] (Mus musculus) PubMed
1499.
The authors found that oxygen negatively regulates biofilm development by influencing the activity of sigma(B).[sigma factor B in strain 1457] (Mus musculus) PubMed
1500.
SdrF alone was able to mediate bacterial adherence to implanted ventricular assist device drivelines; SdrF appears to play a key role in the initiation of ventricular assist device driveline infections caused by S. epidermidis [SdrF] (Mus musculus) PubMed
1501.
presence of the gene encoding SesI among isolates obtained from several patient groups that commonly experienced S. epidermidis infections (SesI, Staphylococcus epidermidis surface protein I) (Mus musculus) PubMed
1502.
Regulation of biofilm formation by sigma B is a common mechanism in Staphylococcus epidermidis and is not mediated by transcriptional regulation of sarA. (Mus musculus) PubMed
1503.
ACME (arginine catabolic mobile element)-arcA-positive isolates were found in meticillin-resistant Staphylococcus haemolyticus (MRSH) with a high prevalence and clonal diversity. {ACME-arcA] (Mus musculus) PubMed
1504.
The protein product of the S. sciuri mecA can efficiently participate in cell wall biosynthesis and build a cell wall using the cell wall precursors characteristic of the S. aureus host [MECA] (Mus musculus) PubMed
1505.
The protein product of pbpD was identified as PBP4 with a molecular mass of 84 kDa, one of the six penicillin binding proteins present. [pbpD] (Mus musculus) PubMed
1506.
Our results provide further support for the proposition that the resistance determinant mecA of methicillin-resistant Staphylococcus strains has evolved from S. sciuri pbpD (Mus musculus) PubMed
1507.
Experimental animal infection suggested that an inactivation of dipeptidyl peptidase IV attenuates greatly its high virulence of Chinese virulent strains of SS2.[dipeptidyl peptidase IV] (Mus musculus) PubMed
1508.
various expression levels of glucosyltransferase isozymes are associated with the ability of distinct Streptococcus mutans genotypes to grow as biofilms [GtfB, GtfC] (Mus musculus) PubMed
1509.
role for enolase in S. mutans attachment, clearance, or breach of the bloodstream barrier [alpha-enolase] (Mus musculus) PubMed
1510.
HtrA plays an important role in the biogenesis of extracellular proteins including surface associated glycolytic enzymes and in biofilm formation of S. mutans.( HtrA ) (Mus musculus) PubMed
1511.
Study demonstrates that mutacin I gene regulation can be divided into two pathways: that dependent on irvA (an inducible repressor) and irvA-independent.[mutacin I, irvA] (Mus musculus) PubMed
1512.
data are consistent with a role for GbpA in facilitating development of biofilms harboring taller microcolonies via binding to alpha-1,6-linkages within glucan [GbpA] (Mus musculus) PubMed
1513.
variation in comC among 36 clinical strains of S. mutans collected from geographically diverse sources is reported [comC] (Mus musculus) PubMed
1514.
Two genes, designated as relP and relQ, encoding novel enzymes that are directly involved in (p)ppGpp synthesis, are identified.[RelP, RelQ] (Mus musculus) PubMed
1515.
In Strep. mutans, lactoylglutathione lyase is involved in the detoxification of methylglyoxal. [lactoylglutathione lyase] (Mus musculus) PubMed
1516.
Based on the enzyme-regulator complex structure observed in this study, an allosteric mechanism for dCD regulation, is proposed.[dCD] (Mus musculus) PubMed
1517.
corresponding residues of alpha-1,6-hydrolyzing enzymes participate in the determination of the substrate specificity of these enzymes[dextran glucosidase ] (Mus musculus) PubMed
1518.
The SmFnB protein of S. mutans is a fibronectin-binding protein that may contribute to the pathogenesis of infective endocarditis.[SmFnB] (Mus musculus) PubMed
1519.
Inactivation of ComCDE, HK/RR11 or both systems attenuate the virulence and cariogenicity of S. mutans. [ComC, ComD, comE, HK, RR11] (Mus musculus) PubMed
1520.
results suggest that RecA has a relationship with biofilm formation [RecA AND Streptococcus mutans MT8148] (Mus musculus) PubMed
1521.
The gene dut, encoding dUTPase from the dental pathogen Streptococcus mutans, was amplified from S. mutans genomic DNA.[dut] (Mus musculus) PubMed
1522.
OXA1 complements a lack of yidC2 in S. mutans.[yidC2] (Mus musculus) PubMed
Lnu(C) confers resistance to lincomycin by adenylylation of lincomycin [Lnu(C)] (Mus musculus) PubMed
1525.
scaAB gene encoding for putative adherence and aggregation factor was cloned and sequenced; its inactivation increased the tendency of Streptococcus agalactiae to aggregation. (Mus musculus) PubMed
1526.
C5a peptidase binding to integrins by the Arg-Gly-Asp motifs may stabilize conformational changes required for substrate binding [C5a peptidase] (Mus musculus) PubMed
1527.
data suggest that a minimum intracellular concentration of the delta subunit of RNA polymerase is necessary for this organism to cause disease [RNA polymerase delta subunit] (Mus musculus) PubMed
1528.
These results demonstrate considerable genetic diversity of the bac (C protein beta-antigen}gene and upstream regions of invasive and noninvasive GBS, which may contribute to the variability of bac expression levels among strains [Bac] (Mus musculus) PubMed
1529.
gene encoding Srr-2 located within a putative accessory secretory locus that included secY2 & secA2 homologues; results indicate the restriction digest pattern III-3/ST-17 lineage expresses Srr-2 & is highly virulent in model of neonatal sepsis [Srr-2] (Mus musculus) PubMed
1530.
study shows that CAMP factor binds to GPI-anchored proteins, and that this interaction involves the carbohydrate core of the GPI-anchor (Mus musculus) PubMed
1531.
In frame deletion showed that GBS80 is a major component protein of the antigenic pilus-like structures in Streptococcus agalactiae. (Mus musculus) PubMed
1532.
RovS specifically binds to the promoter regions of fbsA. (RovS) (Mus musculus) PubMed
1533.
To our knowledge, this is the 1st report of erm(T) in GBS, the 2nd bacterial species from humans in which the erm(T) gene has been identified, and the 3rd erm gene to be found in inducibly clindamycin resistant GBS.[erm(T)] (Mus musculus) PubMed
1534.
FbsA-induced Fbg aggregates consist of thicker fibers organized in a cage-like structure[FbsA--fibrinogen-binding protein expressed ] (Mus musculus) PubMed
1535.
results of the present study support the conclusion that CAMP factor does not bind to immunoglobulin IgG [CAMP factor] (Mus musculus) PubMed
1536.
study concludes that a chromosomally integrated, composite transposon is associated with ermB-type macrolide resistance in GBS [ErmB] (Mus musculus) PubMed
1537.
Deletion of the srr-1 gene in the genome of S. agalactiae revealed that this gene plays a role in bacterial binding to human K4 and that it is involved in adherence to epithelial HEp-2 cells.[Srr-1] (Mus musculus) PubMed
1538.
These results are consistent with the hypothesis that ScpB binds to a motif created by the juxtaposition of multiple Fn molecules.[ScpB] (Mus musculus) PubMed
1539.
sortases are responsible for polymerization of the pilus structure, while SrtA is required to covalently attach it to the cell wall, utilizing ancillary pilus subunit GBS150 as the anchor protein.[SrtA and SrtC in strain 515] (Mus musculus) PubMed
1540.
Group B protective surface protein and 5'-nucleotidase family protein were 2 major immunoreactive proteins detected in the whey of infected cows. [Group B protective surface protein, 5'-nucleotidase family protein] (Mus musculus) PubMed
1541.
The MtaR transcription factor controls genes involved in arginine transport and biosynthesis, methionine transporters, virulence factors, and plasminogen activators. [MtaR] (Mus musculus) PubMed
1542.
CiaR is a crucial factor for intracellular survival and disease pathogenesis.[CiaR] (Mus musculus) PubMed
1543.
CspA abolished the abilities of CXC chemokines to attract and activate neutrophils. [CspA] (Mus musculus) PubMed
1544.
Serine-rich repeat 1 glycoprotein (srr-1 protein)plays an important role in crossing the blood-brain barrier and in the development of streptococcal meningitis. (Mus musculus) PubMed
1545.
lmb gene has been cloned, expressed in Escherichia coli, purified and crystallized[laminin-binding protein ] (Mus musculus) PubMed
results support the hypothesis of an allosteric transition from a conformation with low affinity for ATP to a form with high affinity, which would be induced by the presence of ATP or GTP [UMP kinase] (Mus musculus) PubMed
1548.
identified ComW as a new positive factor involved in regulation of competence for genetic transformation in Streptococcus pneumoniae [ComW] (Mus musculus) PubMed
1549.
COOH-terminal region could act as a pedestal, placing the active site in proximity to the peptidoglycan (peptidoglycan synthesis regulatory factor (PBP3)) (Mus musculus) PubMed
1550.
localization and properties studied, particularly polymerization in an ATP-dependent manner [FtsA, strain Rx1] (Mus musculus) PubMed
1551.
The biochemical characterization of one alpha-galactosyltransferase, WciS (Cap8H), a member of GT family 4 is reported.[WciS; Cap8H] (Mus musculus) PubMed
1552.
while comW is not needed for ComX (sigma(X)) synthesis, it acts both in stabilization of sigma(X) and in its activation (ComW and ComX) (Mus musculus) PubMed
1553.
The genotype of pbp1a, pbp2x, pbp2b, mefA, and ermB of S. pneumoniae strains isolated from children with community acquired pneumonia are reported.[pbp1; pbp2x; pbp2b; mefA; ermB] (Mus musculus) PubMed
1554.
a role for srtA as a pneumococcal fitness factor in experimental models of pneumonia and bacteraemia [sortase A] (Mus musculus) PubMed
1555.
initiation of capsule repeat unit formation by the transfer of a sugar to a lipid acceptor catalyzed by Cps2E; data indicated that Cps2E was catalyzing the addition of Glc-1-P to a polyprenyl phosphate acceptor, likely undecaprenyl phosphate [Cps2E] (Mus musculus) PubMed
1556.
A reaction mechanism is proposed on the basis of kinetic data, the structural model of the Pce:NPPC complex, and the currently accepted mechanism for other Zn-metallophosphoesterases [Pce] (Mus musculus) PubMed
1557.
results suggest that the interaction between PspC and complement regulatory factor H contributes to pneumococcal virulence. [PspC] (Mus musculus) PubMed
1558.
analysis of penicillin-binding protein 1a (PBP1a) sequences from drug-resistant clinical strains reveals the existence of a mutational hotspot at the entrance of the catalytic cleft [PBP1a] (Mus musculus) PubMed
1559.
role of the spr0370-0371 operon containing a putative alkylhydroperoxidase D homologue in pneumococcal virulence and response to oxidative stress [spr0370, spr0371] (Mus musculus) PubMed
1560.
in vitro transcriptional changes in pneumococcal rr09 mutants of two strains, D39 and TIGR4, by microarray analysis [rr09] (Mus musculus) PubMed
1561.
The results showed that the response regulator (RR) and histidine kinase (HK06) regulate virulence factors CbpA and PspA. [RR, HK06] (Mus musculus) PubMed
1562.
Several genes of the GlnR regulon are required at different sites during pathogenesis, with glnA contributing to colonization and survival in the blood and glnP important for survival in the lungs and transition from the lungs to the blood.[glnR] (Mus musculus) PubMed
1563.
findings suggest that SpxR positively regulates spxB transcription in response to energy and metabolic state; SpxR is required for full virulence in a murine model of infection [SpxR] (Mus musculus) PubMed
1564.
PsaR is responsible for the counteracting effects of Mn2+ and Zn2+ on the expression of several virulence genes in S. pneumoniae, suggesting that the ratio of these metal ions exerts an important influence on pneumococcal pathogenesis.[PsaR] (Mus musculus) PubMed
1565.
The pclA mutant was defective in adherence and invasion of host cells in vitro [PclA] (Mus musculus) PubMed
1566.
Insertion mutagenesis in parent and pcsB(+) merodiploid strains indicated that pcsB is essential in serotype 2 S. pneumoniae D39. (Mus musculus) PubMed
1567.
Data show that termination of the transcriptional activity of ComX is not dependent on proteolysis of ComW. New Gene: ComW (Mus musculus) PubMed
1568.
PsaR of D39 and TIGR4 has a strain-specific role in global gene expression and in the development of bacteraemia in mice. [PsaR] (Mus musculus) PubMed
1569.
The contribution of PpmA to virulence can be explained by its strain-specific role in adherence to epithelial cells and contribution to the evasion of phagocytosis. [PpmA/proteinase maturation protein A] (Mus musculus) PubMed
1570.
phage-encoded streptodornase identified through mass spectroscopy, nucleotide sequence, cloning and expression [Sda1 strain M1T1] (Mus musculus) PubMed
1571.
global regulatory factor that contributes to growth phase-dependent synthesis of proteins associated with secondary metabolism and oxidative and thermal stress responses [Streptococcus pyogenes NZ131 (serotype M49), Rgg] (Mus musculus) PubMed
1572.
two genotypes of prtF2 (a fibronectin binding protein), pfbp and fbaB, are described [prtF2] (Mus musculus) PubMed
1573.
the mef(A) gene is carried on different chromosomal genetic elements depending on whether the isolates are susceptible or resistant to tetracycline[mefA] (Mus musculus) PubMed
1574.
crystal structure of the catalytically inactive mutant IdeS-C94S by x-ray crystallography at 1.9-A resolution {IdeS] (Mus musculus) PubMed
1575.
Newly discovered protease IdeS (IgG-degrading enzyme of S. pyogenes, also known as Mac-1-like protein) seems to be atypical cysteine protease with strict specificity for IgG cleavage due to an exosite recognizing the CH2 domain in IgG Fc fragment. [IdeS] (Mus musculus) PubMed
1576.
ciprofloxacin resistance due to point mutations in topoisomerase IV subunit C encoded by parC, mainly replacement of serine-79 by alanine. [ParC] (Mus musculus) PubMed
1577.
Data show that the recombinant Scl protein p176 promotes adhesion and spreading of human lung fibroblast cells through an alpha2beta1 integrin-mediated interaction [sc1] (Mus musculus) PubMed
1578.
The efflux of telithromcyin from S. pyogenes, resulting in reduced activity, is related to the presence of the mef(A) gene. (Mus musculus) PubMed
1579.
A comparison different mef(A) elements of Streptococcus pyogenes for a possible chimeric genetic nature, i.e. a transposon inserted into a prophage. [MefA] (Mus musculus) PubMed
1580.
data indicate that human Fibrinogen bound to Streptococcus pyogenes M5 protein promotes phagocytosis resistance by inhibiting complement deposition via the classical pathway [M5 protein] (Mus musculus) PubMed
1581.
The present study investigated an association between the presence of the prtF2 gene and internalisation efficiency in group A streptococci isolated from patients with invasive disease. [prtF2] (Mus musculus) PubMed
1582.
findings suggest CovR regulation of the covR promoter (Pcov) is direct; CovR was sufficient to mediate repression of Pcov; this repression was enhanced by phosphorylation of the protein [CovR] (Mus musculus) PubMed
1583.
prtF1 is associated with erythromycin resistance [prtF1] (Mus musculus) PubMed
1584.
study presents evidence for a novel protease-protease inhibitor couple, SpeB-Spi, in the Streptococcus pyogenes[cysteine protease SpeB] [Spi] (Mus musculus) PubMed
1585.
MsmR positively regulates FCT region genes including Nra and cytolysin-mediated translocation system genes [MsmR] (Mus musculus) PubMed
1586.
SpeB could cause the mitochondria damage to the polymorphonuclear cells, preventing immune clearance at an early infectious stage (SpeB) (Mus musculus) PubMed
1587.
controls iron homeostasis and has a role in disease production (MtsR - Mts repressor) (Mus musculus) PubMed
1588.
CovR is sufficient to repress transcription from the sag promoter (CovR) (Mus musculus) PubMed
1589.
The prevention of the cell surface export of SDH affects the virulence properties of group A Streptococcus (GAS). (Mus musculus) PubMed
1590.
NADase enhance S.pyogenes virulence in vivo. (NADase) (Mus musculus) PubMed
1591.
crystal structure of delta1-pyrroline-5-carboxylate (P5CR) determined at 2.0 angstroms [P5CR] (Mus musculus) PubMed
1592.
allelic diversity of streptococcal DNase B (sdaB) gene was investigated in 83 strains with 14 emm genotypes; distribution of each allele was generally emm genotype-specific [DNase B (sdaB)] (Mus musculus) PubMed
1593.
required for virulence in zebrazfish and role in iron acquisition pathway both in vitro and in vivo [SiuG] (Mus musculus) PubMed
1594.
RscA is a member of the MDR1 family of ABC transporters, is required for growth of GAS at 40 degrees and is repressed by CovR [RscA][CovR] (Mus musculus) PubMed
1595.
data indicate that binding of human plasma proteins plays an important role in determining the location of opsonic and non-opsonic epitopes in streptococcal M5 protein [M5 protein] (Mus musculus) PubMed
1596.
Seroconversion of IdeS in patients with pharyngotonsillitis and erysipelas leads to inactivation of enzyme activity, supporting the view that the enzyme plays an important role during streptococcal infection [IdeS] (Mus musculus) PubMed
1597.
findings show that serum opacity factor (SOF) interacts with HDL in human blood by binding to apoA-I and apoA-II and causing the release of HDL lipid cargo, which coalesces to form lipid droplets, resulting in opacification [SOF] (Mus musculus) PubMed
1598.
Results describe a eukaryotic-type signaling system in group A Streptococcus, including a eukaryotic-type Ser/Thr kinase (SP-STK) and phosphatase (SP-STP) and their endogenous substrate histone-like protein (SP-HLP) [SP-STK, SP-STK]. (Mus musculus) PubMed
1599.
DNase Sda1 is both necessary and sufficient to promote Group A Streptococcus neutrophil resistance and virulence in a murine model of necrotizing fasciitis. [Sda1] (Mus musculus) PubMed
1600.
CodY protein identified as a pleiotropic transcription regulator with global features [CodY] (Mus musculus) PubMed
1601.
the high virulence of the type M3-f strain is associated with the decreased binding of type M3-f CsrR to its target sequences [CsrR] (Mus musculus) PubMed
1602.
study shows for the first time that residues Arg101, Arg114, His102, and His115 in both the a1 and a2 repeat domains of PAM can mediate high affinity plasminogen binding [PAM] (Mus musculus) PubMed
1603.
signal sequence of M protein promotes secretion at the division septum, whereas that of PrtF preferentially promotes secretion at the old pole [M protein; PrtF] (Mus musculus) PubMed
1604.
phosphorylated CovR represses transcription of rivR directly by binding to conserved sequences located downstream from the promoter to block procession of RNA polymerase [CovR] (Mus musculus) PubMed
1605.
ScpC represents a novel GAS virulence factor functioning to directly inactivate a key element of the host innate immune response.[ScpC] (Mus musculus) PubMed
1606.
Here, we describe a novel plasminogen-binding M protein, the plasminogen-binding group A streptococcal M protein (PAM)-related protein (Prp). [Prp] (Mus musculus) PubMed
1607.
The results provide further evidence that Rgg contributes to growth phase-dependent gene regulation in strain NZ131.[Rgg] (Mus musculus) PubMed
1608.
These data establish that cytolysin-mediated translocation is discriminatory, and that NAD glycohydrolase is a multidomain protein that plays an active role in its translocation. [NAD glycohydrolase] (Mus musculus) PubMed
1609.
analyzed the SpeC-Vbeta2.1 interaction by mutating all SpeC residues that make contact with Vbeta2.1 and determined the energetic and functional consequences of these mutations [SpeC] (Mus musculus) PubMed
1610.
results support the involvement of NAPlr in inflammatory cell accumulation in glomerular tufts and functional abnormality of glomerular microvasculature such as hyperpermeability [NAP1r] (Mus musculus) PubMed
1611.
structure-function studies of previously uncharacterized glycogen-binding modules in the surface-anchored pullulanase PulA; multivalent binding to glycogen leads to a strong interaction with alveolar type II cells in mouse lung tissue [PulA] (Mus musculus) PubMed
1612.
silC and silCR form a novel regulatory circuit that controls the streptococcal invasion locus transcription [SILC, SILCR] (Mus musculus) PubMed
1613.
data suggest that PerR has a greater impact on the transcriptome than can be predicted by its binding sites and that pmtA functions to link metal homeostasis and oxidative stress responses[pmtA] (Mus musculus) PubMed
1614.
We conclude that DRS (distantly related to SIC[streptococcal inhibitor of complement]) shares several of the properties of SIC, and therefore can be considered an important virulence factor of M12 GAS and an aid to colonization of the host mucosae. (Mus musculus) PubMed
1615.
The results obtained by quantitative real-time PCR using the M49 strain NZ131 showed that CodY influenced Streptococcus pyogenes gene activity in a dynamic fashion, with differential responses detected for 26 genes.[CodY protein] (Mus musculus) PubMed
1616.
This study is the first to characterize global gene regulation by a group A Streptococcus two-component system in response to a specific environmental stimulus.[CsrR, CsrS] (Mus musculus) PubMed
1617.
describe how bacteriophage-encoded group A Streptococcus DNase (Sda1), which facilitates the pathogen's escape from neutrophil extracellular traps, serves as a selective force for control of virulence regulatory sensor kinase mutation[ Sda1 ] (Mus musculus) PubMed
1618.
crystal structures of GluR from Streptococcus pyogenes in both inhibitor-free and inhibitor-bound forms [MurI or glutamate racemase] (Mus musculus) PubMed
1619.
In this study, the addition of M1 protein to human blood or purified peripheral blood mononuclear cells led to a dose-dependent increase of pro-coagulant activity, which was mediated by an upregulation of tissue factor on monocytes. [M1 protein] (Mus musculus) PubMed
1620.
study reports that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation [M1 protein] (Mus musculus) PubMed
1621.
Soluble M1 protein is a novel streptococcal superantigen, which contributes to the excessive T cell activation and hyperinflammatory response seen in severe invasive streptococcal infections. (Mus musculus) PubMed
1622.
Heterologous expression in Escherichia coli showed that SipA2, along with the pilus backbone protein T3 and the sortase SrtC2, is required for polymerization of the T3 protein.[SipA in strain GAS AM3] (Mus musculus) PubMed
1623.
The data revealed that, in Plasminogen, the species specificity of VEK-30 binding in human and mice is entirely dictated by two lysine residues.[PAM protein] (Mus musculus) PubMed
1624.
HtrA plays an indirect role in the maturation of cysteine protease SpeB.[HtrA, SpeB] (Mus musculus) PubMed
1625.
we have identified a functional interaction between Scl1 and plasma FH, which may contribute to GAS evasion of complement-mediated opsonization and phagocytosis.[Scl1 in strain MGAS6169] (Mus musculus) PubMed
1626.
protein H and M1 protein of the highly pathogenic S. pyogenes AP1 strain bind full-length beta(2)GPI and prevent its processing into antibacterial peptides.[protein H and M1 in strain AP1] (Mus musculus) PubMed
1627.
These results suggest a novel SPE B mechanism, one which degrades serum C3 and enables GAS to resist complement damage and opsonophagocytosis. [SpeB in strain A20] (Mus musculus) PubMed
1628.
Our data indicate that horizontal transfer of SSA by lysogenic phages among GAS can occur across the M-type barrier; these data also provide further support for the hypothesis that toxigenic conversion can occur via lysogeny between species. [SSA] (Mus musculus) PubMed
1629.
1)Rgg is identified as a novel sensoregulator of streptococcal H2O2 resistance.(rgg) 2) ahpCF operon knockouts demonstrated that the gene products decompose H2O2 and protect GAS against peroxide stress. (ahpC)(ahpF) (Mus musculus) PubMed
1630.
SPEA and SMEZ does not had effect on global protein expression and on transcription of genes encoding the secreted exoproteins.[SPEA, SMEZ] (Mus musculus) PubMed
1631.
In this report Nra activates pilus gene transcription and MsmR represses nra and pilus gene transcription [Nra], MsmR] (Mus musculus) PubMed
1632.
Stimulation of the delta(2) (ParA) ATPase activity and its polymerization on DNA required ability of omega(2) (ParB) to bind parS DNA and its N-terminus (ParA and ParB). (Mus musculus) PubMed
1633.
the findings provide in vivo support of the hypothesis that SpeB-mediated inactivation of LL-37 at the streptococcal surface represents a bacterial resistance mechanism at the infected tissue site in patients with severe GAS tissue infections.[SpeB] (Mus musculus) PubMed
1634.
Streptococcal pyrogenic exotoxin B (SPE B) potentially causes immunosuppression by cleaving human S-adenosylhomocysteine hydrolase (AdoHcyase). (Mus musculus) PubMed
1635.
IgG and 1/2Fc binding to the streptococcal surface was studied and correlated to IdeS activity.[IdeS] (Mus musculus) PubMed
1636.
These data indicate that Dpr provides protection from hydrogen peroxide stress by preventing the Fenton reaction, and Dpr was identified as a novel stress protein that protects against several stresses in group A streptococci.[Dpr in strai A-20] (Mus musculus) PubMed
1637.
challenge with the ScpC mutant that does not degrade IL-8 resulted in more severe systemic disease with higher bacteremia levels and mortality than did challenge with the wild-type strain.[ScpC in strain S291] (Mus musculus) PubMed
1638.
Mga was required for autoaggregation and biofilm-like growth on an abiotic surface. [Mga] (Mus musculus) PubMed
1639.
TrxR is the first TCS shown to regulate Mga expression. Because it is CovR repressed, TrxR defines a new pathway by which CovR can influence Mga to affect pathogenesis in the GAS.[TrxR in strain SF370] (Mus musculus) PubMed
1640.
covR/S operon generates covR/S transcript and monocistronic covR transcripts [covR/S from strains A-20, SF370, SW117, NZ131, SW602, SW603 or SW604 (Mus musculus) PubMed
1641.
The authors suggest that low level of luxS expression seems to provide an advantage for bacterial survival in conditions that can be encountered during infections.[luxS] (Mus musculus) PubMed
1642.
Lzp is a novel immunoglobulin-binding protein that may play a role in helping S. pyogenes escape detection by the host immune system. (Lzp) (Mus musculus) PubMed
1643.
analysis of a prokaryotic Scl1 collagen sequence motif that mediates binding to human collagen receptors, integrins alpha2beta1 and alpha11beta1 [Scl1] (Mus musculus) PubMed
1644.
CovR and CovS mediates the grow under iron starvation and the presence of human antimicrobial peptide LL-37.[CovR and CovS] (Mus musculus) PubMed
1645.
Srv (streptococcal regulator of virulence) is required for biofilm formation, and increased levels of SpeB (cysteine protease) contribures to loss of biofilm phenotype. [Srv, SpeB] (Mus musculus) PubMed
1646.
Modeling of the ScpA-C5a complex indicates that the substrate binds with carboxyl-terminal residues (65-74) extended through the active site and core residues (1-64) forming exosite-type interactions with the Fn2 domain.[ScpA in strain B220] (Mus musculus) PubMed
1647.
Pska regulation by CovR occurs through binding at a single ATTARA consensus binding sequence. [pska, covR] (Mus musculus) PubMed
1648.
findings suggest that the flexible C-terminal loop of SPE B may play an important role in controlling the substrate binding, resulting in its broad substrate specificity [SPE B] (Mus musculus) PubMed
1649.
Disruption of vfr markedly increased SpeB production in a clinical strain of S. pyogenes and relieved its growth phase dependency.[vfr] (Mus musculus) PubMed
1650.
The authors examined the cluster 9 protein Lsp of Streptococcus pyogenes and found that specific deletion of lsp produced mutants highly attenuated in a murine model of soft tissue infection.[Lsp] (Mus musculus) PubMed
1651.
The authors propose that CovS-mediated regulation of CovR activity plays an important role in the ability of GAS to cycle between pharyngeal and invasive infections.[CovR & CovS] (Mus musculus) PubMed
1652.
The crystal structure of MtsA explains the distinct roles of metal ligands and also reveals potential secondary binding sites that may explain the binding behavior of MtsA for metal ions other than Fe(2+). (Mus musculus) PubMed
1653.
The result indicates that SIC plays a role in the inhibition of S. salivarius BLIS.[SIC] (Mus musculus) PubMed
1654.
The data suggest that Lbp (laminin-binding protein)is primarily a zinc-binding protein, and we suggest that its interaction with laminin in vivo may be mediated via zinc bound to laminin. [Lbp] (Mus musculus) PubMed
1655.
[serum opacity factor]The SOF-catalyzed reaction is the first to target HDL (high-density lipoprotein) rather than its transporters and receptors in a way that enhances reverse cholesterol transport. (Mus musculus) PubMed
1656.
The crystal structure of the mature SpeB is presented to 1.55 A, disclosing a homodimer.[SpeB] (Mus musculus) PubMed
1657.
The production of IL-8 by SPE B in A549 cells is mediated by Fas, and followed by the activation of FADD, caspase 8, MEKK1, ERK and NF-kappaB.[SPEB] (Mus musculus) PubMed
1658.
Crystallization and preliminary crystallographic analysis of an Enterococcus faecalis repressor protein, CylR2 (Mus musculus) PubMed
enterococci use CylL(L)'' to actively probe the environment for target cells, and when target cells are detected, allows the organism to express high levels of cytolysin in response [CylL(L) strain FA2-2] (Mus musculus) PubMed
1661.
important for virulence as well as stress response, and anti-Gls24 immune rabbit serum shows protection against E. faecalis infection in a mouse peritonitis model. [Gls24] (Mus musculus) PubMed
1662.
results indicate that gelatinase is important for the successful in vitro translocation of E. faecalis across human enterocyte-like T84 cells [GelE] (Mus musculus) PubMed
1663.
results indicate that DivIVA is a speceis specific essential gene involved in cell division, cell growth and chromosome segregation [DivIVA] (Mus musculus) PubMed
1664.
Enterococcus faecalis FabN and FabZ protein domain swapping localizes the structural determinants for isomerase activity [FabN] (Mus musculus) PubMed
1665.
development of high-level resistance to penicillins and imipenem depends on point mutations of PBP4 at positions 520 and 605 [PBP4] (Mus musculus) PubMed
1666.
PrgY may sequester or inactivate cCF10 as it is released from the membrane. (cCF10) (Mus musculus) PubMed
1667.
HypR acts as a transcriptional activator, especially during oxidative stress, and appears to be an important virulence factor [HypR] (Mus musculus) PubMed
1668.
results indicate that gls24 is important in the pathogenesis of enterococcal endocarditis [gls24] (Mus musculus) PubMed
1669.
pIP501 tra operon is negatively autoregulated at the transcriptional level by the conjugative DNA relaxase TraA. [TrA] (Mus musculus) PubMed
1670.
The role of CroR as a direct transcriptional activator of the salB expression in E. faecalis is reported.[CroR; SalB] (Mus musculus) PubMed
1671.
results show that the FsrABC system positively & negatively regulates expression of numerous genes between late exponential phase & early stationary phase; also the FsrABC system regulon is independent of the expression of gelE and sprE[FsrA, FsrB, FsrC] (Mus musculus) PubMed
1672.
Increased Ace expression correlated with increased collagen and laminin adhesion. (Ace) (Mus musculus) PubMed
1673.
The effect of siamycin I on the metabolism of fsrC, fsrA, and gelE-sprE transcripts and the subsequent production of gelatinase biosynthesis-activating pheromone is reported.[gelE; sprE; fsrA; fsrC] (Mus musculus) PubMed
1674.
Phosphopantetheine adenylyltransferase is an essential enzyme in the coenzyme A biosynthetic pathway has been cysstallized and the X-ray diffraction data were collected. [phosphopantetheine adenylyltransferase] (Mus musculus) PubMed
1675.
overall reaction rate of HMG-CoA synthase was increased 140-fold[HMG-CoA synthase] (Mus musculus) PubMed
1676.
E. faecalis GelE hydrolyzed C3a and also mediated the degradation of C3b, thereby inhibiting opsonization and the formation of the membrane attack complex resultant from the activation of the complement cascade triggered by C3 activation.[GelE] (Mus musculus) PubMed
1677.
PrkC, a one-component signaling protein containing a eukaryotic-type Ser/Thr kinase domain, modulates inherent antimicrobial resistance and intestinal persistence of E. faecalis. [PrkC] (Mus musculus) PubMed
1678.
we report the crystal structure of the AzoA from E. faecalis determined at 2.07 A resolution with bound FMN ligand[AzoA] (Mus musculus) PubMed
1679.
Gel retardation assays showed that the CroR regulator binds specifically to the glnQHMP promoter.[CroR] (Mus musculus) PubMed
1680.
study describes the crystal structure of ACE19 and compares it with CNA19 crystal structure; present modeling studies presented to localize the collagen-like peptide interactions with ACE19 [ACE protein] (Mus musculus) PubMed
1681.
An ebpR deletion (DeltaebpR) mutant was found to have reduced ebpABC expression with loss of pilus production and a defect in primary adherence with, as a consequence, reduced biofilm formation.[ebpR] (Mus musculus) PubMed
1682.
Surface protein ElrA has a role in the E. faecalis infectious process in vivo and may contribute to E. faecalis virulence by stimulating the host inflammatory response. (ElrA) (Mus musculus) PubMed
1683.
EF_0783 is currently involved in the lysozyme resistance of E. faecalis, peptidoglycan O acetylation and de-N-acetylation are not the main mechanisms conferring high levels of lysozyme resistance to E. faecalis.[EF0783] (Mus musculus) PubMed
1684.
Deletion of bps had a major effect on virulence in murine UTIs; deletion of srtA from OG1RF from a bps mutant had a pronounced effect on biofilm, suggesting that Bps and/or the proteins it anchors may compensate for the loss of SrtA function.[ArtA,Bps] (Mus musculus) PubMed
1685.
the thiol peroxidase (Tpx) deletion mutant showed attenuated virulence in a mouse peritonitis model.[Tpx in strai JH2-2] (Mus musculus) PubMed
1686.
the high-resolution solution structure of the 15.4 kDa homodimer CylR2, the regulator of cytolysin production from Enterococcus faecalis (Mus musculus) PubMed
1687.
DivIVA self-interacts and forms a 10-12 multimeric complex (DivIVA). (Mus musculus) PubMed
1688.
indicate that together with KPR, D-ManDH constitutes a new family of D-2-hydroxyacid dehydrogenases that act on C3-branched 2-ketoacid substrates with various specificities for coenzymes and substrates [D-mandelate dehydrogenase] (Mus musculus) PubMed
1689.
Results showed distinct characteristics in mutation patterns of ermB and ermA. (Mus musculus) PubMed
1690.
these results indicate that the regulator Ers (PrfA-like transcriptional regulator) has a pleiotropic effect, especially in the cellular metabolism and virulence of E. faecalis. [Ers] (Mus musculus) PubMed
1691.
A stem-loop sequestering the Fst ribosome binding site is required for translational repression. (Mus musculus) PubMed
1692.
In the present study, we sum up the characteristics of Ers and provide further evidence that this protein is a member of the PrfA branch of this regulator family. [Ers] (Mus musculus) PubMed
1693.
Tro-105 is a critical residue for FMN binding in azoreductase. [AzoA] (Mus musculus) PubMed
1694.
Data show that GntR family transcriptional activator CitO has a role in the transcriptional regulation of the citrate gene cluster of Enterococcus faecalis [CitO] (Mus musculus) PubMed
1695.
PerA, a gene encoding a putative AraC-type transcriptional regulator, was identified as a regulator of biofilm formation and survival within macrophages and is likely a regulator controlling determinants important to pathogenesis. (Mus musculus) PubMed
1696.
This study showed that the pHTbeta plamids confers the self-aggregation phenotype on E. faecalis, and that the aggregation was controlled by a traB gene.[traB] (Mus musculus) PubMed
1697.
Tn5281 is the main cause of transmission of aac(6')-aph(2") to different isolates in the hospitals studied. [aac(6')-aph(2")] (Mus musculus) PubMed
1698.
paralyzes the human complement system via a two-stage process: by converting circulating C3 to C3b, and by disrupting phagocytosis of human polymorphonuclear leukocytes. [E. faecalis gelatinase GelE] (Mus musculus) PubMed
1699.
multiple functional domains are important in Asc10-mediated interactions with the host during the course of experimental endocarditis and that in the absence of a functional prgB gene, pCF10 carriage is actually disadvantageous in vivo.[Asc10] (Mus musculus) PubMed
Crystal structure of fatty acid/phospholipid synthesis protein PlsX from Enterococcus faecalis. (Mus musculus) PubMed
1702.
Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis (Mus musculus) PubMed
1703.
Since an in-frame deletion of EF1809 resulted in a severe biofilm defect that could be complemented by the cloned wild-type gene, we have designated EF1809 ebrA (enterococcal biofilm regulator).[EbrA] (Mus musculus) PubMed
1704.
the crystal structure of the Ef peptide deformylase complex with Met-Ser-Ala was presented. (Mus musculus) PubMed
1705.
Glutaraldehyde & borane-dimethylamine derivatized EfsQnr by cyclic pentylation of free amines, producing piperidine groups. Crystals diffracted to 1.6 A resolution & were analyzed by single-wavelength anomalous dispersion. (Mus musculus) PubMed
1706.
The authors demonstrated for the first time that Ace can be considered a virulence factor for E. faecalis.[Ace] (Mus musculus) PubMed
1707.
Membrane-bound BcrR has a high affinity for its target DNA. BcrR is a bona fide one-component transmembrane signal transduction system. [BcrR] (Mus musculus) PubMed
1708.
fsrB and to a lesser extent gelE significantly contribute to the virulence of E. faecalis food isolates. [fsrB; gelE] (Mus musculus) PubMed
1709.
The N-terminal domain of spaA possessed high immunoreactivity. [SpaA] (Mus musculus) PubMed
1710.
crystal structure of 1,3,6,8-tetrahydroxynaphthlene synthase (THNS) [THNS] (Mus musculus) PubMed
1711.
the Streptomyces developmental protein WhiD, a member of the WhiB family, binds a [4Fe-4S] cluster (Mus musculus) PubMed
1712.
experiments demonstrated that AbsA1 possesses both kinase and phosphatase activities that are specific for AbsA2 [AbsA1, AbsA2 strain C530] (Mus musculus) PubMed
1713.
VanK has a role in vancomycin resistance in Streptomyces coelicolor (Mus musculus) PubMed
1714.
structure and thermal stability of the first protein (enzyme I, EI) of the PTS in Streptomyces coelicolor is studied by using far-UV circular dichroism (CD) and Fourier transform infrared spectroscopy (FTIR) at pH 7.0 [enzyme I] (Mus musculus) PubMed
1715.
PhoP and its truncated DBD domain were found to bind with high affinity to an upstream region of the pstS and phoRP-phoU promoters close to the -35 sequence of each of these promoters [PhoP] (Mus musculus) PubMed
1716.
The wild-type H+-pyrophosphatase , but not a cysteine-less mutant, is reversibly inactivated by oxidation. (Mus musculus) PubMed
1717.
results strongly suggest that the enzyme responsible for RNA 3'-tail synthesis is polynucleotide phosphorylase (PNPase); moreover, this study shows that both PNPase and the product of SCO3896 are essential[PNPase, SCO3896] (Mus musculus) PubMed
1718.
Nur is a regulator of nickel homeostasis and antioxidative response in S. coelicolor. (Nur) (Mus musculus) PubMed
1719.
transcriptional regulation of macs1-fadD1; identification & characterization of a transcriptional activator, AcsR, whose role is to control growth-phase-dependent induction of the macs1-fadD1 operon by binding to an unusual operator [AcsR, macs1, fad1] (Mus musculus) PubMed
1720.
MreB is not essential for vegetative growth of S. coelicolor, but exerts its function in the formation of environmentally stable spores, and appears to primarily influence the assembly of the spore cell wall. (MreB) (Mus musculus) PubMed
1721.
The data show that the zinc site in RsrA is comprised of Cys11, His37, Cys41, and Cys44.(RsrA) (Mus musculus) PubMed
1722.
the core domain and active sites of FtsY and Ffh which are responsible for GTP hydrolysis, were identified; results indicated that Lys residue in the putative GTP binding loop was the crucial residue for the GTPase activity of NG domain [FtsY, Ffh] (Mus musculus) PubMed
1723.
Studies demonstrate that the increased levels of ribosome recycling factor(RRF) caused by the K88E mutation is responsible for an aberrant stationary-phase event: overproduction of antibiotic [RRF] (Mus musculus) PubMed
1724.
findings suggest that agl3R is one of a number of homologous proteins in Streptomyces that respond to nutritional and/or environmental signals to control genes that affect morphogenesis and antibiotic production [agl3R] (Mus musculus) PubMed
1725.
Some crosses between pairs of recA null mutants generated no detectable recombinants, showing for the first time that conjugal recombination in S. coelicolor is recA mediated [recA] (Mus musculus) PubMed
1726.
The functional actVI-ORFA gene restored expression of actVI-ORF1, which encodes a key reductase in the actinorhodin tailoring step, in the mutant cells, indicating a possible regulatory role of ActVI-ORFA. [ActVI-ORFA] (Mus musculus) PubMed
1727.
results confirm that AsnO and HasP are required for the beta-hydroxylation and phosphorylation of the Asn residue within calcium-dependent antibiotic [hasP, asnO] (Mus musculus) PubMed
1728.
Zur, located downstream of the znuACB operon, encoding a putative zinc uptake transporter: Zur (Mus musculus) PubMed
1729.
cdaX or cchK) encoding MbtH-like proteins in Streptomyces coelicolor is required for biosynthesis of the peptide siderophore coelichelin and the calcium-dependent peptide antibiotic (CDA).[cdaX, cchK] (Mus musculus) PubMed
1730.
cloY is specifically required for the formation of the 3-amino-4,7-dihydroxy-coumarin moiety of the clorobiocin molecule.[cloY] (Mus musculus) PubMed
1731.
the N-terminus was dispensable for FtsY GTPase activity, and that the N-domain plays an essential role in the GTPase activity of the NG domain. In addition, the S.scoelicolor FtsY was able to restore function in an E. coli mutant. (Mus musculus) PubMed
1732.
The studies demonstrate that the subfamily partner CYP158A1, sharing 61% amino acid identity with CYP158A2, can catalyze the same flaviolin dimerization reactions, but it generates just two of the three isomers of biflaviolin that CYP158A2 produces. (Mus musculus) PubMed
1733.
S. coelicolor ParA provides scaffolding for proper distribution of ParB complexes and consequently controls synchronized segregation of several dozens of chromosomes, possibly mediating a segregation and septation checkpoint.[ParA] (Mus musculus) PubMed
1734.
These results suggested that the transcription of hppD is subject to coarse and fine control by a complex regulatory system.[hppD, HpdA, HpdR] (Mus musculus) PubMed
1735.
The septal localization of SffA was dependent on SmeA, suggesting that SmeA may act as an assembly factor for SffA and possibly other proteins required during spore maturation. (Mus musculus) PubMed
1736.
mutation in the N-terminal domain of germacradienol-geosmin synthase of a catalytically essential serine to alanine results in the conversion of farnesyl diphosphate to a mixture of sesquiterpenes [germacradienol-geosmin synthase ] (Mus musculus) PubMed
1737.
the phoA, phoC and phoD promoters showed clear differences in the modulation of their expression by PhoP.[PhoP] (Mus musculus) PubMed
1738.
Further transcriptional analysis on sporulation controlling genes, i.e., whiG, whiB, whiH, and prox, indicated that the regulation of sporulation by ftsY is likely to take effect through whiH.[FtsY and whiH in strain M145] (Mus musculus) PubMed
1739.
SCO1135 open reading frame identified by the insertion encodes a member of the TetR family of transcriptional regulators.[TetR] (Mus musculus) PubMed
1740.
in contrast to a previous postulate, Pol I and its paralog are not essential for replication of Streptomyces chromosomes.[PolA in strains 3454 and 3456] (Mus musculus) PubMed
1741.
A cooperative binding of PhoP initiated at conserved core direct repeats appears to be the mechanism involved in binding of several PhoP monomers to those complex operators (PhoP). (Mus musculus) PubMed
1742.
The chromosomal interruption of dasA resulted in a carbon-source-dependent vegetative arrest phenotype.[DasA] (Mus musculus) PubMed
1743.
the deletion of sco0958 produced a dramatic reduction in neutral lipid production, whereas the overexpression of this gene yielded a significant increase in de novo TAG biosynthesis.[sco0958 in strain M145] (Mus musculus) PubMed
1744.
prokaryotic homolog exhibits remarkable structural similarity to human formylglycine-generating enzyme, including the position of catalytic cysteine residues[ formylglycine-generating enzyme] (Mus musculus) PubMed
1745.
The paper reports that a cellulose synthase-like protein (CslA(Sc)) in Streptomyces has a function in hyphal tip growth and morphological differentiation.[CslA in strain M145] (Mus musculus) PubMed
1746.
Antibiotic pathway-specific activators are mediated through the pleiotropic transcriptional repressor DasR, the regulon of which also includes all N-acetylglucosamine-related catabolic genes.[DasR] (Mus musculus) PubMed
1747.
AbsB controls its own expression by sequentially and site specifically cleaving stem-loop segments of its polycistronic transcript.[AbsB in strain C120] (Mus musculus) PubMed
1748.
RT-PCR experiments showed that expression of novG was detectable in the absence of NovE, and also that expression of novE occurred in absence of NovG. (Mus musculus) PubMed
1749.
TrpRS1 is transcriptionally activated by indolmycin and confers resistance to indolmycin. [TrpRS1] (Mus musculus) PubMed
1750.
OrnA is not transcriptionally or translationally coupled to adpA, a key bldA target for morphological differentiation. [OrnA, adpA, bldA] (Mus musculus) PubMed
1751.
The SCO5883 mutant did not synthesize undecylprodigiosin, while SCO6673 mutant failed to produce calcium-dependent antibiotic.[SCO5883 and SCO6673 homologs in strain M145] (Mus musculus) PubMed
1752.
Data compare ActR's interaction with naturally occurring and synthetic molecules to show that pathway intermediates bind to ActR 5- to 10-fold more tightly than actinorhodin itself [ActR]. (Mus musculus) PubMed
1753.
The endoRNase activity of RNase III is required for the regulation of antibiotic production in S. coelicolor. [Rnc] (Mus musculus) PubMed
1754.
FilP is an intermediate filament-like protein which has a cytoskeletal function in actinobacterial growth and morphogenesis. [FilP] (Mus musculus) PubMed
1755.
the purification of NsrR from the obligate aerobe Streptomyces coelicolor. (Mus musculus) PubMed
1756.
Ppm1 is necessary for the transfer of mannose to endogenous polyprenol phosphate, and glycosylates PstS. [Ppm1] (Mus musculus) PubMed
1757.
The X-ray structure of the two-domain laccase (small laccase) from Streptomyces coelicolor A3(2) was solved at 2.7-A resolution.[Laccase] (Mus musculus) PubMed
1758.
HspR role in adaptation to stresses includes influencing expression of key components of the translational apparatus in addition to molecular chaperone and protease-encoding genes[HspR] (Mus musculus) PubMed
1759.
It is therefore proposed that BldG and SCO3548 form a partner-switching pair that regulates the function of one or more sigma factors in S. coelicolor.[BldG & SCO3548] (Mus musculus) PubMed
1760.
Compared with wild-type strain M145, the rrdA null mutant exhibited increased undecylprodigiosin production and decreased actinorhodin production. (Mus musculus) PubMed
1761.
NepA is a bacterial structural cell wall protein that is important for maintenance of spore dormancy. [NepA] (Mus musculus) PubMed
1762.
PhoP represses directly the transcription of GS genes glnA, glnII, the putative ammonium transporter gene amtB, and the nitrogen regulatory genes glnD and glnK, which form part of the amtB operon (PhoP). (Mus musculus) PubMed
1763.
Nur contains a unique nickel-specific metal site in addition to a nonspecific common metal site (Nur). (Mus musculus) PubMed
1764.
GlnR positively regulated the transcription of nasA via specific binding to a cis-element similar but different from the previously characterized consensus sequence. (GlnR)(nasA) (Mus musculus) PubMed
1765.
report the structure of the Steptomyces coelicolor fatty acid synthase ACP and studies of its binding to malonyl CoA-ACP transacylase.[malonyl CoA-ACP transacylase] (Mus musculus) PubMed
1766.
SsgB is a conserved activator of developmental cell division in morphologically complex actinomycetes (Mus musculus) PubMed
1767.
cpb1 took part in the regulation of chitinase expression in S. lividans[chitinase and cpb1] (Mus musculus) PubMed
1768.
Data suggest that the structure and stability of KcsA reconstituted into native-like membranes differ from those exhibited in detergent solution. (Mus musculus) PubMed
KcsA channel inactivation can be described by a kinetic model in which pH(i) controls inactivation through pH-dependent activation [KcsA] (Mus musculus) PubMed
1771.
Conserved amino acids were mutated in order to investigate a functional role of these residues in catalysis.(acetylxylan esterase A) (Mus musculus) PubMed
1772.
The results presented here support the idea that ClpP1/P2 ensure post-translational control of ClgR regulon members, including ClgR itself.[ClpP1][ClpP2] (Mus musculus) PubMed
1773.
Sodium and potassium ions bind competitively to KcsA with distinct affinities and induce different conformations of the ion-bound protein. (KcsA) (Mus musculus) PubMed
1774.
selectivity and gating functions of Streptomyces lividans KcsA [KcsA] (Mus musculus) PubMed
1775.
Study of the role of the Tat subunits in complex assembly and stability in the membrane and cytoplasm showed that TatB stabilizes TatC, driving Tat complex assembly is suggested for TatC and TatA is a translocator.[TatA, TatB, TatC protein] (Mus musculus) PubMed
1776.
the C-terminal domain of KcsA may contribute to the pH dependent opening of the potassium channel (Mus musculus) PubMed
1777.
A stem-loop structure on the sblA transcript plays a negative role in the regulation of sblA expression and might be involved in the regulation of the specific degradation of the sblA transcript.[sblA] (Mus musculus) PubMed
1778.
Results describe the structure and activity of full-length KcsA, a prototypical K+ channel, in its open, closed and intermediate states [KcsA]. (Mus musculus) PubMed
1779.
Data show that in the KcsA potassium channel, the number and strength of hydrogen bonds between residues in the selectivity filter and pore helix determine the rate and extent of C-type inactivation, which can also be engineered in Kv1.2 channels. (Mus musculus) PubMed
1780.
solid-state NMR studies of the selectivity filter region of KcsA potassium channel[KcsA] (Mus musculus) PubMed
1781.
S-adenosylmethionine controls the expression of bldH through the TTA-codon control in translating bldH mRNA.[bldH] (Mus musculus) PubMed
1782.
effect of mutations of Thr75 in the S4 site of theKcsA K+ channel on the cation dependence of the thermal stability of the tetramer, a phenomenon that reflects the structural role of cations in the filter [KcsA] (Mus musculus) PubMed
1783.
mutation, ion depletion, and K(+) to Na(+) substitution influence SF conformation [KcsA] (Mus musculus) PubMed
1784.
Channel-opening may follow a three-phase pathway. First, the channel unlocks itself from the closed state; second, it opens; and third, it locks itself in the open conformation.[KcsA] (Mus musculus) PubMed
1785.
XylR acts as a repressor in the S. lividans xylose operon and xylose isomerase(XylA) activity. [XylR, XylA] (Mus musculus) PubMed
1786.
Replacement of an elusive C-terminal domains with a known tetrameric scaffold could potentially assist the expression of potassium channels. [potassium channel KcsA] (Mus musculus) PubMed
1787.
Expression of the pstS gene is regulated by the carbon source but is not controlled by the PhoP regulator. [pstS, PhoP] (Mus musculus) PubMed
1788.
These results suggest that ArfA is a new promoter-binding regulator for antibiotic production and for bldH expression in S. lividans (ArfA) (Mus musculus) PubMed
1789.
The results uphold the premise that polyP and the C-terminal arginines are decisive elements in KcsA channel regulation[KcsA] (Mus musculus) PubMed
1790.
Synthetic antigen-binding fragments (Fabs) were used as crystallographic chaperones to determine the structure of full-length KcsA at 3.8 A, as well as that of its isolated C-terminal domain at 2.6 A.[KcsA] (Mus musculus) PubMed
1791.
The authors propose that selective permeation from the intracellular side primarily results from a large energy barrier blocking filter entry for Na(+) and Li(+) in the presence of K(+), not from a difference of binding affinity between ions. (Mus musculus) PubMed
1792.
Data show that MiaB protein is a bifunctional system, involved in both thiolation and methylation of isopentenyl-adenosine (i(6)A) [MiaB]. (Mus musculus) PubMed
1793.
MreB and actin display significantly different assembly properties despite high structural homology [MreB] (Mus musculus) PubMed
1794.
X-ray structure of TrmE; the structural and biochemical studies presented here suggest how TrmE most likely directly participates in at least the first step of the cmnm modification reaction in the anticodon loop of certain tRNAs [TrmE] (Mus musculus) PubMed
1795.
determined the crystal structure of the hetero-octameric (HisGS)4HisZ4 tmATPPRTase complex at 2.5 A resolution [HisGs, HIsZ] (Mus musculus) PubMed
1796.
Results describe the crystal structure of Thermotoga maritima tRNase Z at 2.6-A resolution, and present a docking model with tRNA that suggests how tRNase Z may recognize the substrate tRNAs [tRNAse Z]. (Mus musculus) PubMed
1797.
biophysical analysis of how IGP synthase excludes water to optimize ammonia transfer [IGP synthase, PDB 1GPW] (Mus musculus) PubMed
1798.
domain orientation in free L11 shows limited similarity to that of ribosome-bound L11 in complex with elongation factor, EF-G [ribosomal protein L11] (Mus musculus) PubMed
1799.
the crystal structure at 3.85 A resolution of the RNA component of Thermotoga maritima ribonuclease P [ribonuclease P, RNA component] (Mus musculus) PubMed
1800.
Data describe the cloning, purification and characterization of HydE and HydG proteins from the thermophilic organism Thermotoga maritima [HydE and HydG]. (Mus musculus) PubMed
Data support the idea that interactions of the DNA duplex template arm with the RecG protein are the major sites of binding and production of translocation [RecG] (Mus musculus) PubMed
1803.
BglT employs a fully stepwise E1(cb) mechanism involving anionic transition states to catalyze the hydrolysis of glycosidic bonds, in contrast to all other currently characterized glycosidase families. (BglT, 6-phospho-beta-glucosidase) (Mus musculus) PubMed
1804.
evolutionarily related family of aldolases distinct from the N-acetylneuraminate lyase (NAL) family [2-keto-3-deoxy-6-phosphogluconate aldolase] (Mus musculus) PubMed
1805.
structural analysis of the complex reveals the presence of three binding-subsites, which explains why T. maritima invertase exhibits a higher affinity for raffinose than sucrose [invertase] (Mus musculus) PubMed
1806.
crystal structure of a soluble FtsH construct that is functional in caseinolytic and ATPase assays[FtsH] (Mus musculus) PubMed
1807.
endo-beta-1,4-D-galactanase gene of Thermotoga maritima was cloned and overexpressed in Escherichia coli [endo-beta-1,4-D-galactanase] (Mus musculus) PubMed
1808.
investigation of the crystal structure of inorganic polyphosphate/ATP-NAD kinase, PPNK_THEMA, a protein from Thermotoga maritima [PPNK_THEMA] (Mus musculus) PubMed
1809.
TM1367 crystal structure reveals unexpected similarities to members of the cyclophilin (peptidylprolyl isomerase) fold[ TM1367 ] (Mus musculus) PubMed
1810.
crystal structures of the full-length Thermotoga maritima CorA in an apparent closed state and its isolated cytoplasmic domain at 3.9 A and 1.85 A resolution, respectively [CorA] (Mus musculus) PubMed
1811.
the DnaA homolog (tmaDnaA) of Thermotoga maritima forms open complexes with the predicted origin region (tma-oriC) in vitro. TmaDnaA has a strong and specific affinity for ATP/ADP as well as for 12-mer repeating sequences within the tma-oriC [DnaA] (Mus musculus) PubMed
1812.
The NMR structures of the unphosphorylated Thermotoga maritima protein TM1442 at pH 4.8 and of the phosphorylated TM1442 (TM1442-P). at pH 7.0 are presented, and a functional interaction of TM1442 with TM0733 is characterized (TM1442) (Mus musculus) PubMed
1813.
determined a 2.9 angstrom resolution structure of CorA that reveals a pentameric cone-shaped protein; two potential regulatory metal binding sites are found in the N-terminal domain that bind both Mg2+ and Co2+ [CorA] (Mus musculus) PubMed
1814.
This work describes the first direct observation of the interaction between P1 and P4 domains in CheA. (CheA) (Mus musculus) PubMed
1815.
Results describe the structure of a histidine kinase (ThkA) complexed with a response regulator (TrrA) in the two-component regulatory system from hyperthermophile Thermotoga maritima [ThkA, TrrA]. (Mus musculus) PubMed
1816.
Asp-52 and His-222 directly contribute the proton transfer of tRNase Z catalysis (tRNase Z). (Mus musculus) PubMed
1817.
The PLP synthase holoenzyme consists of two subunits. [Pyridoxal-5-phosphate synthase] (Mus musculus) PubMed
1818.
The crystal structure of TM1602 was determined to 2.3 A resolution using the MAD method. The final model includes a monomer (residues 3-174), one Ni2+ ion, one K+ ion, and 97 water molecules in the asymmetric unit [TM1602] (Mus musculus) PubMed
1819.
The structures of hTK1 and of the Thermotoga maritima thymidine kinase (TmTK) in complex with the bisubstrate inhibitor TP4A, is reported. (Mus musculus) PubMed
1820.
The crystal structure of a putative transcriptional regulator protein TM1030 from Thermotoga maritima, a hyperthermophilic bacterium, was determined by an unusual multi-wavelength anomalous dispersion method at 2.0 (Mus musculus) PubMed
1821.
Thermodynamic properties calculated in the dynamic context of the protein structure provided new insight into the mechanism of glutamate dehydrogenase thermostabilization (glutamate dehydrogenase). (Mus musculus) PubMed
1822.
Rates of methionine formation in the presence and absence of TM0269 and S-adenosylmethionine demonstrate that both TM0269 and S-adenosylmethionine are required for reactivation of the inactive cob(II)alamin form of TM0268 (TM0268 and TM0269). (Mus musculus) PubMed
1823.
The conditions that regulate MreB's monomer-to-polymer assembly reaction, the critical concentrations of that reaction, the manner in which MreB uses nucleotides, its stability, and the structure of the assembled polymer, are characterized.[MreB] (Mus musculus) PubMed
1824.
ATP-DnaA-oriC unwinding element complexes specifically bound the upper strand of single-stranded DUE[DnaA] (Mus musculus) PubMed
1825.
functional switch of Tm HtrA is embedded in the sentinel of the helical lid in terms of substrate accessibility[High-temperature requirement A] (Mus musculus) PubMed
1826.
analysis of structure-function relationships and gating mechanisms in the CorA Mg2+ transport system [CorA] (Mus musculus) PubMed
1827.
recombinant protein, cloned from Thermotoga maritima genomic DNA, was overproduced in Esherichia coli and crystallized in 25%(v/v) PEG 4000, 100 mM NaCl and sodium citrate buffer pH 5.0 at 291 K [ folate-dependent tRNA methyltransferase] (Mus musculus) PubMed
1828.
measurement of the conformational flexibility of the protein by hydrogen-deuterium exchange [GAPDH] (Mus musculus) PubMed
1829.
HU bends DNA and constrains negative DNA supercoils in the presence of topoisomerase I (HU). (Mus musculus) PubMed
1830.
Data indicate that the flexible arm of tRNase Z is not essential for pre-tRNA binding but affects the cleavage site selection: [tRNase Z] (Mus musculus) PubMed
1831.
Thermotoga maritima XseA/B homologs TM1768 and TM1769 showed nuclease activity that is magnesium dependent and is inhibited by phosphate ions, which distinguish it from E. coli ExoVII (TM1768 and TM1769). (Mus musculus) PubMed
1832.
the crystal structure of SecA bound to the SecY complex, with a maximum resolution of 4.5 angstrom (A), obtained for components from Thermotoga maritima [SecA; Sec Y] (Mus musculus) PubMed
1833.
these findings suggest that the substrate specificity of TM0416p is likely to differ substantially from those of other D-tagatose 3-epimerase family enzymes.[TM0416p] (Mus musculus) PubMed
1834.
findings indicate that the putative active site nucleophile is not required for FDTS catalysis, and no alternative nucleophilic residues capable of serving this function can be identified [flavin-dependent thymidylate synthase] (Mus musculus) PubMed
1835.
Study found a new class of bifurcating [FeFe] hydrogenase in which the exergonic oxidation of ferredoxin is used to drive the unfavorable oxidation of NADH. New Gene: [FeFe] hydrogenase (Mus musculus) PubMed
1836.
Study analyzed the biochemical properties of a TF:S7 complex from Thermotoga maritima and determined its crystal structure & obtained an atomic-level picture of a promiscuous chaperone in complex with a physiological substrate protein.[tig] (Mus musculus) PubMed
1837.
Study reports the structure of the complex between the entire cytoplasmic portion of Thermotoga maritima class I HK853 and its cognate, RR468, as well as the structure of the isolated RR468, both free and BeF(3)(-) bound.[HK853, RR468] (Mus musculus) PubMed
1838.
In this study, they characterized cbf11+ and cbf12+, the two CSL genes of Schizosaccharomyces pombe, in order to elucidate the CSL function in fungi. They provide evidence supporting their identity as genuine CSL genes. (Mus musculus) PubMed
1839.
Flo8 and Mss11 bind indirectly to UAS2-1 of the STA1 promoter by interacting with Ste12 and Tec1 [STA1] (Mus musculus) PubMed
1840.
In this article, we extend these findings by uncovering a role for H2B phosphorylation at serine 10 (Ser10) in another biological event that is associated with dramatic alterations in higher-order chromatin structure, meiosis [histone 2b] (Mus musculus) PubMed
1841.
PIG-Y appeared to be directly associated with PIG-A, implying that PIG-Y is the key molecule that regulates GPI-GnT activity by binding directly to the catalytic subunit PIG-A. PIG-Y is probably homologous to yeast Eri1p, a component of GPI-GnT. [PIG-Y] (Mus musculus) PubMed
1842.
The purification and characterization of the three Snf1-activating kinases (Sak1, Tos3, and Elm2) of Saccharomyces cerevisiae are reported.[Elm2] (Mus musculus) PubMed
1843.
We demonstrate that polyprenol reductase preferentially acts on typical polyprenols with 13-18 isoprene residues but can reduce much longer polyprenols with even 32 isoprene residues (Mus musculus) PubMed
1844.
Four active forms of CK2, composed of alphaalpha'betabeta', alpha(2)betabeta', alpha'(2)betabeta', and a free alpha'-subunit were isolated from wild-type yeast. (protein kinase CK2) (Mus musculus) PubMed
1845.
novel biotin biosynthesis gene identified and characterized;results suggest that Bio6p acts in an unknown step of biotin synthesis before KAPA synthesis [B106] (Mus musculus) PubMed
1846.
Raf60 is a component of the Rpd3 histone deacetylase complex that it is required for normal Rpd3 complex activity and repression of gene expression (Mus musculus) PubMed
1847.
The dephosphorylation of gammaH2AX by the HTP-C is necessary for efficient recovery from the DNA damage checkpoint [H2AX histone] (Mus musculus) PubMed
1848.
We found that strains deleted for either NAT3 or MDM20 displayed different growth rates and morphologies in specific stress conditions, demonstrating that the two NatB subunits have partly individual functions [natB] (Mus musculus) PubMed
1849.
An analysis of the amino acid residues necessary for binding of YS11 to 18s rRNA in S. cerevisiae is presented.[YS11] (Mus musculus) PubMed
1850.
crystal strycture of Geranylgeranyl-Diphosphate Synthase type III [GGPP3] (Mus musculus) PubMed
1851.
The kinetics and thermodynamics of the alkaline and acid conformational transitions of a Lys 79 --> Ala/Asn 52 --> Gly (A79G52) variant of iso-1-cytochrome c are studied[iso-1-cytochrome c] (Mus musculus) PubMed
1852.
Two classes of prohibitin dependent mutation (pbd1 and pbd2) were isolated and characterised. pbd1 mutant slightly extended lifespan, whereas in contrast, the pbd2 mutation resulted in a shortening in both the mean- and the maximum-lifespan. [Pbd1, Pbd2] (Mus musculus) PubMed
1853.
Sequences in the N-terminal cytoplasmic domain of Saccharomyces cerevisiae maltose permease, Mal61, are required for vacuolar degradation but not glucose-induced internalization. [Mal61] (Mus musculus) PubMed
1854.
These results indicate that the short-chain dehydrogenase-reductase-like Gly motif likely provides support to the overall structure of xylose reductase (XR), but it does not contribute directly to coenzyme binding in this XR. [xylose reductase] (Mus musculus) PubMed
1855.
analysis of the mechanism of Rbp1p function [Rbp1p] (Mus musculus) PubMed
1856.
TOR also regulates late stages of ribosome maturation in the nucleoplasm via the nuclear GTP-binding protein Nog1. [TOR] (Mus musculus) PubMed
1857.
crystal structure of Saccharomyces cerevisiae eEF3, showing that it consists of an amino-terminal HEAT repeat domain, followed by a four-helix bundle and two ABC-type ATPase domains, with a chromodomain inserted in ABC2 [eEF3] (Mus musculus) PubMed
1858.
PER1 encodes an evolutionary conserved component of the Glycosylphoshatidylinositol (GPI) anchor remodeling pathway, highlighting the close connection between the lipid remodeling of GPI and raft association of GPI-anchored proteins.[Phospholipase A2] (Mus musculus) PubMed
1859.
These results support a eukaryotic stalk structure in which P1 proteins are internally located while P2 proteins are more external and accessible to interact with other cellular components. [Ribosomal phosphoprotein P1, P2] (Mus musculus) PubMed
1860.
Comparison of 2D (15)N-HSQC spectra of IA(3) in water & in 23% 2,2,2-trifluoroethanol shows that individual residue cross peaks of IA(3) become more dispersed in TFE, indicating that it undergoes an unstructured to structured transition in TFE.[IA(3)] (Mus musculus) PubMed
1861.
Although pol eta could accommodate large bulges and continue synthesis without obstruction, bulge structures in the template, but not in the primer, caused termination of the T7 DNA replication complex[T7 DNA polymerase ] (Mus musculus) PubMed
1862.
These results support the existence of different components within the basic transcription complexes that antagonistically interact with the NC2 repressor.[Nc2 protein] (Mus musculus) PubMed
1863.
Might compensate the function of enzymes that detoxify H(2)O(2). (Mpr1, an N-acetyltransferase [not the same as RPN11, a metalloproteinase sometimes known as Mpr1] (Mus musculus) PubMed
1864.
A model that explains the role of multiple cyclin E/Sic1 degrons is provided by the findings that Fbw7 and Cdc4 dimerize, that Fbw7 dimerization enhances the turnover of a weakly associated cyclin E in vivo.[Fbw7] (Mus musculus) PubMed
1865.
Study determined crystal structure of fatty acid synthase, which illuminates how this enzyme is initially activated and then carries out multiple steps of synthesis in each of six sterically isolated reaction chambers.[Alpha subunit of FAS] (Mus musculus) PubMed
1866.
These results suggest that polyadenylated mRNA can enter P-bodies, and an mRNP complex including poly(A) mRNA, Pab1p, eIF4E, and eIF4G2 may represent a transition state during the process of mRNAs exchanging between P-bodies and translation.[EIF4E, EIF4G] (Mus musculus) PubMed
1867.
AID action is transcription-dependent in yeast and that strong and transcription-dependent hypermutation and hyperrecombination are induced by AID if cells are deprived of THO. (Mus musculus) PubMed
1868.
Hsp104 actively unfolds its polypeptide substrates during processing[HsP104 protein] (Mus musculus) PubMed
1869.
Q72E-yeast VDAC1 requires three glutamate residues, located in two cytosolic loops, for the interaction of VDAC1 with RuR and subsequent protection against cell death[Vdac1] (Mus musculus) PubMed
1870.
ADD66 encodes an approximately 30-kDa soluble, cytosolic protein and that the chymotrypsin-like activity of the proteasome is reduced in add66Delta mutants.[A1Pi] (Mus musculus) PubMed
1871.
Gamma-glutamyltransferase (GGT) is involved in recycling cadmium-glutathione complex in vacuoles. (Mus musculus) PubMed
1872.
The interaction between Bir1p and Sli15p is specifically involved in regulating septin dynamics during anaphase.[Septin] (Mus musculus) PubMed
1873.
chaperones within distinct complexes can play unique roles during endoplasmic reticulum-associated degradation (ERAD), establishes a role for Sse1/Hsp110 in ERAD, and identifies Hsp110 as a target to lower cholesterol[ Hsp110, apoB29 and apoB48] (Mus musculus) PubMed
1874.
Phosphatidylethanolamine and phosphatidylserine stimulate GTPase-activating protein (GAP) activity of Rga1p and Rga2p toward Cdc42p, whereas PI(4,5)P(2) inhibits it. [Rga1; Rga2] (Mus musculus) PubMed
1875.
One of the differentially expressed genes, YBR174W, is required for optimal growth in synthetic medium.[YBR174W] (Mus musculus) PubMed
1876.
A previously unrecognized function for the Saccharomyces cerevisiae Sad1-UNC-84 domain protein Mps3 in regulating telomere positioning in mitotic cells, is reported.[UNC-84] (Mus musculus) PubMed
1877.
Role for the cell cycle-regulated protein kinase Dbf2p in promoting V-ATPase function and mediating sorbic acid stress tolerance.[Dbf2p, V-ATPase] (Mus musculus) PubMed
1878.
in both yeast and amoebae, TM9 proteins (Dictyostelium Phg1a, b, and c; and S. cerevisiae Tmn1, 2 and 3) participate in the control of specific cellular functions in response to changing nutrient conditions (Mus musculus) PubMed
1879.
Fpk1p/Fpk2p are upstream activating protein kinases for Lem3p-Dnf1p/Dnf2p. (Fpk1p and Fpk2p) (Mus musculus) PubMed
1880.
confirms the important role of the N-terminal segment of cofilin in interactions with G-actin[G-actin] (Mus musculus) PubMed
1881.
Pba3-Pba4 orchestrates formation of a specific type of proteasome, the first example of a trans-acting factor that controls assembly of alternative proteasomal complexes.[Pba3, Pba4] (Mus musculus) PubMed
1882.
The structure of the Dmp1-Dmp2-alpha5 complex reveals how this chaperone functions in proteasome assembly and why it dissociates from proteasome precursors before the beta-rings are assembled.[Dmp1, Dmp2] (Mus musculus) PubMed
1883.
the Fra-Grx complex is an intermediate between the production of mitochondrial Fe-S clusters and transcription of the iron regulon [Fra1-Fra2] (Mus musculus) PubMed
1884.
results suggest that Myr1 is a novel factor linked to the secretory pathway and important cellular regulatory mechanisms [myr1] (Mus musculus) PubMed
1885.
analysis of the key surfaces on p35/ARPC2 required for Arp2/3 complex-mediated actin assembly and cellular function [ARPC2] (Mus musculus) PubMed
1886.
These results reveal a previously unknown ubiquitin-dependent mechanism for controlling the pre-mRNA splicing pathway.[ubiquitin] (Mus musculus) PubMed
1887.
This work provides a mechanistic framework for investigating the toxicity of TDP-43 aggregation relevant to human disease.[TDP-43] (Mus musculus) PubMed
1888.
Overexpression of DGK1 causes the appearance of phosphatidate-enriched membranes around the nucleus and leads to its expansion, without proliferating the cortical endoplasmic reticulum membrane[diacylglycerol kinase 1] (Mus musculus) PubMed
1889.
The results of functional analyses demonstrated roles for Mpp6 in the surveillance of both pre-rRNA and pre-mRNAs and in the degradation of "cryptic" noncoding RNAs. (Mus musculus) PubMed
1890.
Data show that Iqg1p interacts with three targets in Saccharomyces cerevisiae: myosin essential light chain (Mlc1p), calmodulin (Cmd1p) and the small GTPase Cdc42p [Iqgp1]. (Mus musculus) PubMed
1891.
Structural dynamics increase with increasing Mg(2+) concentrations, enabling the enzyme to reach its active state[D135 ribozyme] (Mus musculus) PubMed
1892.
Adaptation to H(2)O(2) treatment was demonstrated to occur when anaerobically grown wild-type cells were aerated for a short time that was reliant on the Yap1p and Skn7p transcription factors.[Yap1, Skn7p] (Mus musculus) PubMed
1893.
Results identified yeast Rpl31, a component of the large ribosomal subunit, as a contact point of the ribosome-associated complex at the polypeptide tunnel exit [Rpl31]. (Mus musculus) PubMed
1894.
structural comparison of dimethylallyltransferase (DMATase) in the complex with unliganded bacterial DMATase provides a molecular basis of ordered substrate binding by DMATase[dimethylallyltransferase] (Mus musculus) PubMed
1895.
One contains glycosylated pro-alpha-factor, the second contains the GPI-anchored proteins Cwp2p, Ccw14p and Tos6p and the third is enriched with the hexose transporter, Hxt1p[tos6] (Mus musculus) PubMed
1896.
DEAD-box proteins CYT-19, Mss116p, and Ded1p can achieve complete strand separation using a single ATP[CYT-19] (Mus musculus) PubMed
1897.
Yeast PARK9 helps to protect cells from manganese toxicity, revealing a connection between Parkinson disease genetics (alpha-syn and PARK9) and an environmental risk factor (PARK9 and manganese).[PARK9] and [PARK1=alpha synuclein]. (Mus musculus) PubMed
1898.
MSRA and MSRB helps to preserve the function of cellular FeS clusters from oxidative inactivation. [MSRB] (Mus musculus) PubMed
1899.
These data support a model in which autophagy is negatively regulated by the Tap42-PP2A pathway.[PP2A] (Mus musculus) PubMed
1900.
These findings provide the first evidence that NoCut is triggered by the interaction of acetylated chromatin with the passenger complex at the spindle midzone.[NoCut] (Mus musculus) PubMed
1901.
Ubiquitination of histone H2B and methylations of histone H3 are required for the release of Cdc14 from nucleolar chromatin. [H3, H2B] (Mus musculus) PubMed
1902.
Biophysical, structural and genetic studies presented here reveal that CDC26 stabilizes the structure of APC6, a core TPR protein required for APC integrity.[APC6] (Mus musculus) PubMed
1903.
(Fra2 protein) Inclusion of Fra2 in the Grx3/4 iron-sulfur complex causes a change in the cluster stability and coordination environment. (Fra2 protein) (Mus musculus) PubMed
1904.
PRD-4 is an ortholog of mammalian checkpoint kinase 2 (Chk2); expression of prd-4 is regulated by the circadian clock and, reciprocally, PRD-4 physically interacts with the clock component FRQ, promoting its phosphorylation [PRD-4] (Mus musculus) PubMed
1905.
POD6 acts together with COT1 and is essential for polar cell extension in a kinesin/dynein-dependent manner in N. crassa.[Pod6, Cot1] (Mus musculus) PubMed
1906.
(GPR-4):The involvement of a predicted G-protein-coupled receptor (GPCR), GPR-4, during growth and development in the presence of different carbon sources in N. crassa is investigated. (Mus musculus) PubMed
1907.
The cellular distribution of catalase-2 and catalase-4 was determined: CAT2 and CAT4. (Mus musculus) PubMed
1908.
In Neurospora, both nonhomologous integration pathways, MUS-52-dependent and MUS-52-independent, require MUS-53 (a homolog of human Lig4), which functions in the final step of nonhomologous end-joining. [Mus-53] (Mus musculus) PubMed
1909.
cysteine residues of NADH:ubiquinone oxidoreductase 11.5kDa subunit are likely important to acquisition & stabilization of the correct conformation [NADH:ubiquinone oxidoreductase 11.5kDA subunit] (Mus musculus) PubMed
1910.
identified QIP, a putative exonuclease, as a QDE-2-interacting protein; disruption of qip in Neurospora impaired gene silencing and siRNA accumulated, mostly in nicked duplex form [Qip protien] (Mus musculus) PubMed
1911.
Clockswitch (csw-1), is required for clock function; its product localizes to the frq promoter, is required for proper frq expression, and has an impact on chromatin structure. (Mus musculus) PubMed
1912.
Expression of the nde-3 gene is up-regulated in the late exponential growth phase of N. crassa.(Nde-3) (Mus musculus) PubMed
1913.
Data indicate that RRG-1 controls vegetative cell integrity, hyperosmotic sensitivity, fungicide resistance, and protoperithecial development through regulation of the OS-4/OS-5/OS-2 MAPK pathway [RRG-1]. (Mus musculus) PubMed
1914.
These results suggest that BiP and FKBP22 form a folding helper complex with a high chaperoning capacity in the endoplasmic reticulum of Neurospora crassa.[BiP, FKBP22] (Mus musculus) PubMed
1915.
Results describe the CPC1 regulon, the ortholog of Saccharomyces cerevisiae GCN4, by profiling transcription in wild-type and cpc-1 mutant strains. (Mus musculus) PubMed
1916.
The association of FKBP22 with the molecular chaperones and folding catalysts Grp170, alpha-subunit of glucosidase II, PDI, ERp38, and CyP23, is demonstrated. (Mus musculus) PubMed
1917.
CAO-2 is the enzyme responsible for the oxidative cleavage of torulene in the neurosporaxanthin biosynthetic pathway [CAO-2] (Mus musculus) PubMed
1918.
The subcellular location and traffic of two selected chitin synthases (CHS) from Neurospora crassa, CHS-3 and CHS-6, labeled with green fluorescent protein (GFP), were studied by high-resolution confocal laser scanning microscopy.[Spk, CHS 6] (Mus musculus) PubMed
1919.
Several mixed detergent systems were analyzed for their ability to fold Neurospora mitochondrial porin.[Mitochondrial porin] (Mus musculus) PubMed
1920.
These findings suggest that OS-2 MAP kinase(OS-2 Mitogen-Activated Protein Kinase) regulated the expression of cat-1 and cat-3 transcriptionally, and probably that of cat-3 posttranscriptionally. (Mus musculus) PubMed
1921.
CYT-19 mediates ATP-dependent unfolding of both the native conformation and a long-lived misfolded conformation of a group I catalytic RNA with efficiencies that depend on the stabilities of the RNA species but not on specific structural features [CYT-19] (Mus musculus) PubMed
1922.
These results suggest that OS-2 participates in the regulation of ccg-1 gene. (OS-2)(ccg-1) (Mus musculus) PubMed
1923.
Meiotic Silencing by Unpaired DNA (MSUD), a mechanism that silences expression from unpaired DNA during meiosis, requires the dcl-1 (but not the dcl-2) gene for its function.[DCL-1] (Mus musculus) PubMed
1924.
These data indicate that differential expression of FRQ isoforms is not required for temperature compensation but rather provides a means to fine-tune period length in response to ambient temperature.[FRQ] (Mus musculus) PubMed
1925.
QDE-1 is enriched at the transgenic locus required to trigger post-transcriptional gene silencing (QDE-1). (Mus musculus) PubMed
1926.
Studies show show that Neurospora U2 snRNP associated factor (U2AF65) binds RNA with low affinity and specificity, apparently evolving with its disappearing binding site [U2AF65] (Mus musculus) PubMed
1927.
Genetic and molecular analysis of the temperature-sensitive mutant un-17 carrying a mutation in the gene encoding poly(A)-polymerase in Neurospora crassa (Mus musculus) PubMed
1928.
Study concludes that the MID-1 protein plays a role in regulation of ion transport via Ca(2+) homeostasis and signaling. In the absence of normal ion transport activity, the mutant exhibits poorer growth. (Mus musculus) PubMed
1929.
RHO-4 plays important roles in regulating cytoskeleton and are essential for hyphal tip growth. [Rho4] (Mus musculus) PubMed
1930.
These results verify the role of Ncap conformational changes in gating the photic response of N. crassa and indicate that LOV-LOV homo- or heterodimerization may be a mechanism for regulating light-activated gene expression.[VVD] (Mus musculus) PubMed
1931.
These data indicate a functional link between COT1 and MAPK signaling in regulating filamentous growth, hyphal fusion, and sexual development.[COT1, MAK1, MAK2] (Mus musculus) PubMed
1932.
Study concludes that DNA methylation in Neurospora is mainly the result of a unidirectional pathway in which DIM-5 methylates histone H3K9 and then the DIM-2/HP1 complex recognizes the resulting trimethyl-H3K9 mark via the chromo domain of HP1.[HP1] (Mus musculus) PubMed
1933.
RHO1/LRG1 function in parallel with COT1 in coordinating apical tip growth.[COT1, LRG1] (Mus musculus) PubMed
1934.
Growth of basal hyphae is significantly reduced in mik-1, mek-1, and mak-1 deletion mutants on solid medium. [mik-1, mek-1, and mak-1] (Mus musculus) PubMed
1935.
establish an unexpected plasticity to the Polyketide Synthases fold, unanticipated from structural studies of other members of this enzyme family[oxoalkylresorcylic acid synthase] (Mus musculus) PubMed
1936.
The cyanide hydratase assembly is stabilized by two dyadic interactions between dimers across the one-start helical groove. [CHT, cyanide hydratase] (Mus musculus) PubMed
1937.
The study indicates that the zinc transport proteins encoded by tzn1 and tzn2 are members of the zinc uptake system regulated by zinc status in N. crassa. New Gene: tzn1 (Mus musculus) PubMed
1938.
T1hex-1 transcript and a variant splicing T2hex-1 transcript are up-regulated at alkaline pH (hex-1) (Mus musculus) PubMed
1939.
strains with a mutation in the vivid (vvd) gene, previously shown to code for the photoreceptor involved in photo-adaptation, exhibit conidiation rhythms in constant illumination as well as in constant darkness [vvd] (Mus musculus) PubMed
1940.
A PP1-impaired mutant showed increased H3S10p and selective reduction of methylation of H3K9 and DNA, similarly, amino acid substitutions of H3S10 abolished methylation of H3K9 and DNA [PP1, wild type] (Mus musculus) PubMed
1941.
Data suggest that BEM46 plays a role in a signal transduction pathway involved in determining or maintaining cell type-specific polarity.[BEM46] (Mus musculus) PubMed
1942.
Neurospora crassa SPA-2-GFP fusion protein was found at the apex of forming branches but not in septa, suggesting that it participates only in areas of tip growth. (Mus musculus) PubMed
1943.
CaBP has an Mr of around 6 kDa. and one mole binds 2 moles of calcium and is partially inhibited by other divalent cations. [CaBP] (Mus musculus) PubMed
1944.
Results suggest that DEAD-box proteins such as Mss116 and Cyt-19 function as RNA chaperones by virtue of their RNA-unwinding mechanism, which enables refolding of localized RNA regions or structures without globally disrupting RNA structure [Cyt-19]. (Mus musculus) PubMed
1945.
The female and male fertility-1 (fmf-1) mutant of Neurospora crassa maps to a homologue of the Schizosaccharomyces pombe Ste11p (fmf-1). (Mus musculus) PubMed
1946.
This is the first direct comparison of a monomeric Kinesin-3 with its dimeric full-length counterpart, and the kinetic changes observed here may also apply to other Kinesin-3 motors. (Mus musculus) PubMed
1947.
Lah-1 and Lah-2 promote equitable Woronin body inheritance by providing a link to the cell cortex. [Lah-1, Lah-2] (Mus musculus) PubMed
1948.
The rate of nuclear import of newly synthesized FRQ is progressively reduced in a phosphorylation-dependent manner, leading to an increase in the steady-state level of cytoplasmic FRQ[FRQ, no specific strain indicated] (Mus musculus) PubMed
1949.
GPIT-2, a glycosylphosphatidylinositol (GPI)transamidase subunit, is required for the addition of GPI anchors onto GPI-anchored proteins. [GPIT-2] (Mus musculus) PubMed
1950.
Leishmania eEF1B may help protect the parasite from lipid peroxidation [eEF1B] (Mus musculus) PubMed
1951.
SMP-1, a member of a new family of small myristoylated proteins in kinetoplastid parasites, is targeted to the flagellum membrane [SMP-1] (Mus musculus) PubMed
1952.
Leishmania major pteridine reductase is inhibited by 2,4,6-triaminoquinazoline, as shown by x-ray crystallography (Mus musculus) PubMed
1953.
LmPOT1 is a polyamine permease from the protozoan parasite Leishmania major [LmPOT1] (Mus musculus) PubMed
1954.
The expression and characterization of an ascorbate peroxidase from L. major is reported.[APX] (Mus musculus) PubMed
1955.
identification and characterization of MRK1, an essential, putative MEK kinase [MRK1] (Mus musculus) PubMed
1956.
identifiction and functional characterization of PEX19; evidence provided that PEX19 associates with other PEX membrane proteins [PEX19] (Mus musculus) PubMed
1957.
molecular characterization of LRNase HIIC; it is essential for the survival of the parasite [LRNase HIIC] (Mus musculus) PubMed
1958.
The Leishmania major mucolipin-like A and B genes (lmmlA and lmmlB) encode two proteins of 776 and 590 amino acids, respectively, and may be classified among the mucolipins family [transient receptors potential mucolipin (TRPML). [lmmlA], [lmmlB] (Mus musculus) PubMed
1959.
results demonstrate that SCA1 encodes a sc-D-ArapT and provide the first example of heterologous expression of a D-ArapT gene [SCA1] (Mus musculus) PubMed
1960.
The crystal structure of L. major GLO1 reveals differences in active site architecture to both human GLO1 and the nickel-dependent Escherichia coli GLO1.(GLO1) (Mus musculus) PubMed
determination of the three-dimensional structure of the Lmaj006129AAA at 1.6 angstroms, encompassing residues 7-163 [Lmaj006129AAA] (Mus musculus) PubMed
1963.
The isolation and characterization of phosphodiesterase A (PDEA), phosphodiesterase B1 (PDEB1), and phosphodiesterase B2 (PDEB2) are reported. [PDEA; PDEB1; PDEB2] (Mus musculus) PubMed
1964.
genetic analysis and characterization of Leishmania major UDP-glucose pyrophosphorylase (Mus musculus) PubMed
1965.
first report of a metalloid (antimonate) reductase (ACR2) with a bifunctional role in protein tyrosine phosphatase activity to dephosphorylate phosphotyrosine residues in leishmanial proteins [ACR2] (Mus musculus) PubMed
1966.
analysis of Leishmania major surface metalloprotease GP63 (leishmanolysin) [GP63] (Mus musculus) PubMed
1967.
RIC1 is a novel form of the F1 ATP synthase alpha-subunit that acts as the major energy transducer for tRNA import [RIC1] (Mus musculus) PubMed
Over-expression of the active pyroglutamyl peptidase I (PPI), but not inactive PPI, in L. major impaired differentiation from the procyclic promastigote to the infective metacyclic promastigote. [pyroglutamyl peptidase I] (Mus musculus) PubMed
1970.
intracellular localization of PRP1; mechanism of pentamidine resistance mediated by PRP1 is proposed [PRP1] (Mus musculus) PubMed
1971.
Shuttle mutatgenesis as a source of reagents for targeted disruption of RNA polymerase III (RPC2) in L. major is reported.[RPC2] (Mus musculus) PubMed
1972.
Kin13-2 localizes essentially to the flagellum, and its overexpression produces flagellar shortening and knockdown yields long flagella. [Kin13-2] (Mus musculus) PubMed
1973.
These results taken together suggest that Leishmania LmAQP1 has multiple physiological roles, being involved in solute transport, volume regulation and osmotaxis.[AQP1] (Mus musculus) PubMed
1974.
Reported here are the kinetic characterization of the LmjPDEB1 (phosphodiesterase)catalytic domain and its crystal structure as a complex with 3-isobutyl-1-methylxanthine (IBMX) at 1.55 A resolution. [PDEB1] (Mus musculus) PubMed
1975.
Functional characterization of recombinant and native LmPEX7 revealed that this receptor bound the PTS2 protein fructose-1,6-bisphosphate aldolase.[PEX7] (Mus musculus) PubMed
1976.
Thymidine kinase (TK1) was identified and role in flagellum formation, promastigote shape and growth, and virulence in mouse macrophages demonstrated. [TK1] (Mus musculus) PubMed
1977.
The results of cytochrome c binding, compound I formation rate and activity assay suggested that Trp208 in LmAPX was essential for electron transfer from cytochrome c to heme ferryl but was not indispensable for ascorbate oxidation.[Ascorbate peroxidase] (Mus musculus) PubMed
1978.
Leishmania trypanothione synthetase-amidase structure reveals a basis for regulation of conflicting synthetic and hydrolytic activities [TSA, trypanothione synthetase-amidase] (Mus musculus) PubMed
1979.
shows the essentiality of the topS gene encoding the L. major DNA topoisomerase IB small subunit [DNA topoisomerase IB small subunit] (Mus musculus) PubMed
1980.
Lmaj3'NT/NU may constitute a new important compound of the L. major purine scavenging pathway and could be involved in sandfly parasite survival and colonization. (Lmaj3'NT/NU) (Mus musculus) PubMed
1981.
The cloning of ORC1 from L. major, and the analysis of its expression in L. major promastigotes were reported. (Mus musculus) PubMed
1982.
The kinetoplastid Leishmania major Selenophosphate synthetase genes were cloned and the protein overexpressed and purified to apparent homogeneity. (Mus musculus) PubMed
1983.
overexpression of LmAPX, an ascorbate peroxidase, caused depletion of the mitochondrial ROS burden and conferred a protection against mitochondrial cardiolipin oxidation and increased tolerance to H2O2 [LmAPX] (Mus musculus) PubMed
1984.
This is the first report where metalloid and glycerol transport can be dissected by a single mutation at the extracellular pore entry of LmAQP1 channel.(LmAQP1) (Mus musculus) PubMed
1985.
certain LACK-altered peptide ligands are able to induce T cell responses with a protective phenotype in an infectious disease such as leishmaniasis.[LACK] (Mus musculus) PubMed
1986.
ATG12 localized in part to ATG8-containing puncta, suggestive of a functional ATG5-ATG12 conjugation pathway in the parasite.[Atg12] (Mus musculus) PubMed
1987.
Myosin XXI expression was more predominant in the promastigote stage where it was preferentially localized in the proximal region of the flagellum.[Myosin XXI] (Mus musculus) PubMed
1988.
Kinetic analysis shows a novel role of residue D70 in the excision rate of 3'-blocking ends by the class II AP endonuclease LMAP (LMAP). (Mus musculus) PubMed
1989.
LmaNT3 and LmaNT4 are nucleobase/proton symporters;LmaNT3 functions optimally at neutral pH and LmaNT4 at low pH[LMANT3 AND LMANT4] (Mus musculus) PubMed
1990.
Results suggest a role for mammalian and parasite casein kinase 1alpha in regulating IFNAR1 stability and type I IFN signaling. (Mus musculus) PubMed
1991.
structure of the La motif from the Trypanosoma brucei La protein to 1.6 A resolution [La protein] (Mus musculus) PubMed
1992.
TbRAB4 is involved in regulation of fluid-phase traffic to the lysosome in T. brucei but not in receptor-mediated endocytosis or recycling [Rab4] (Mus musculus) PubMed
1993.
Results identify a subunit of a tRNA processing complex (T. brucei MT40 , which is a putative methyltransferase and a homolog of Saccharomyces cerevisiae Gcd14[MT40] (Mus musculus) PubMed
1994.
Data suggest that cathepsin B (tbcatB), but not rhodesain, is essential for T. brucei survival in culture and is the most likely target of the diazomethane protease inhibitor Z-Phe-Ala-CHN(2) in T. brucei [tbcatB]. (Mus musculus) PubMed
1995.
arginine 735 is essential for RNA interference (argonaute 1) (Mus musculus) PubMed
1996.
Results describe a novel protein kinase, TbECK1, and the regulatory function of its long C-terminal extension [ECK1]. (Mus musculus) PubMed
1997.
X-ray diffraction analysis of farnesyl diphosphate synthase from Trypanosoma brucei [Farnesyl diphosphate synthase (FPPS)] (Mus musculus) PubMed
1998.
Results report the crystal structure of the catalytic domain of Trypanosoma brucei RNA editing ligase 1 (TbREL1) at 1.2 A resolution, in complex with ATP and magnesium [TbREL1]. (Mus musculus) PubMed
1999.
role for TbTRF4 in transcription performed by all three nuclear RNA polymerases (Mus musculus) PubMed
2000.
Rab5A and Rab5B are required for endocytosis in trypanosomes. [Rab5A and Rab5B proteins] (Mus musculus) PubMed
2001.
MRP1 and MRP2 are not essential for RNA editing but may have a regulatory role in the editing of specific transcripts and other RNA processing activities [MRP1 (gBP21) and MRP2 (gBP25)] (Mus musculus) PubMed
2002.
histone H3 variant is enriched at telomeres in Trypanosoma brucei [histone H3] (Mus musculus) PubMed
2003.
SNIP is part of an organized nucleoplasmic machinery responsible for processing of SL RNA [SNIP exonuclease] (Mus musculus) PubMed
2004.
KU80 may have a role in telomere length regulation in Trypanosoma brucei (KU80). (Mus musculus) PubMed
2005.
Glycosome provides protection of trypanosomes from the dangerous design of glycolysis. (PEX14 AND hexokinase AND phosphofructokinase). (Mus musculus) PubMed
2006.
NOPP44/46 is required for formation of the large ribosomal subunit in Trypanosoma brucei (Mus musculus) PubMed
2007.
over-expression caused two-fold down regulation of cytochrome oxidase subunit IV, and cytochrome c1 protein and a four-fold up-regulation of GPEET procyclin in the procyclic form. [Aox, alternative oxidase] (Mus musculus) PubMed
2008.
ARL1 is essential for viability in T. brucei bloodstream parasites (ARL1). (Mus musculus) PubMed
2009.
FRDm1 is involved in the maintenance of the redox balance in the mitochondrion, as proposed for the ancestral soluble FRD presumably present in primitive anaerobic cells [FRDm1 fumarate reductase] (Mus musculus) PubMed
2010.
kinetics for the cruzain catalyzed hydrolysis and structural examination for rational drug design (cruzain) (Mus musculus) PubMed
2011.
TbMP42 contributes both endo- and exoribonuclease activity to the RNA editing reaction cycle [TbMP42] (Mus musculus) PubMed
2012.
required for accurate and efficient cytokinesis but not for exit from mitosis. [MOB1-A, MOB1-B] (Mus musculus) PubMed
2013.
results show that degradation of polyadenylated RNAs in T. brucei mitochondria can occur through a unique mechanism that requires the polymerization of UTP into RNAs, presumably by the RET1 TUTase [RET1] (Mus musculus) PubMed
2014.
TbLRTP suppresses basal body replication and subsequent flagellar biogenesis and plays a critical role for the LRTP family of proteins in the control of the cell cycle. (Mus musculus) PubMed
TbMBAP1 is essential for both incoming and recycling membrane traffic.[TbMBAP1] (Mus musculus) PubMed
2017.
TbRAB11 controls recycling and is essential in both life stages of T. brucei but its primary role is subject to developmental variation. (Mus musculus) PubMed
2018.
identifiction and functional characterization of PEX19; findings show that show that knockdown of PEX19 in results in reduced growth and a glycosome biogenesis defect [PEX19] (Mus musculus) PubMed
2019.
Results suggest that Trypanosoma brucei TTAGGG repeat-binding factor (tbTRF), like vertebrate TRF2, is essential for telomere end protection. (Mus musculus) PubMed
2020.
The T. brucei ARL1 protein is expressed only in the mammalian bloodstream form of the parasite, in which it is localized to the Golgi apparatus (ARL1 protein) (Mus musculus) PubMed
2021.
findings show that genetic ablation of TbZFP1 compromises repositioning of the mitochondrial genome, a specific event in the strictly regulated differentiation programme [ZFP1] (Mus musculus) PubMed
2022.
the TRF4/SNAP(c)/TFIIA complex binds specifically to the SL RNA gene promoter upstream sequence element and is absolutely essential for spliced-leader RNA gene transcription in vitro [TRF4, SNAP(c), TFIIA] (Mus musculus) PubMed
2023.
TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression [tSNAP42, TBP] (Mus musculus) PubMed
2024.
CBF5 has a role in stabilization of small nucleolar RNAs of the H/ACA-like family [CBF5] (Mus musculus) PubMed
2025.
Two splicing factors (Prp31 and Prp43) were found to be essential for both trans- and cis-splicing pathways, suggesting that splicing factors are shared by these two reactions. [Prp31, prp43] (Mus musculus) PubMed
2026.
DMC1 is transcribed in the bloodstream stage where the gene can be mutated by reverse genetic disruption; mutation does not result in detectable alterations in DNA repair, recombination or antigenic variation efficiency in this life cycle stage [DMC1] (Mus musculus) PubMed
2027.
These results indicate that the cellular distribution of trypanosome lytic factor (TLF) is influenced by Serum resistance-associated protein (SRA) expression and may directly determine the organism's susceptibility to TLF. (Mus musculus) PubMed
2028.
The T.brucei TFIIB(like) protein localizes to the nucleus, specifically binds to the spliced leader RNA (SLRNA) promoter, interacts with RNA polymerase II, and is required for SLRNA transcription [TFIIB-like] (Mus musculus) PubMed
2029.
The observation that both PEX5 and PEX7 are essential for the viability of the parasite indicates that the respective branches of the glycosome-import pathway in which each receptor acts might be interesting drug targets.[PEX7] (Mus musculus) PubMed
2030.
TbcatB protein is a parasitic cysteine protease with a role in protein degradation and iron acquisition (Mus musculus) PubMed
2031.
the complement-binding protein gene is deleted from the genome of Western African strains of monkeypox virus (Mus musculus) PubMed
2032.
the RPO132 subunit of the RNA polymerase has a role in transcription elongation [RPO132] (Mus musculus) PubMed
2033.
RING protein p28 can mediate the formation of polyubiquitin conjugates; p28 is ubiquitinated in vivo and ubiquitin colocalizes with p28 to virus factories independently of an intact RING domain [RING protein p28] (Mus musculus) PubMed
2034.
cloned and sequenced the VGF gene of vaccinia virus strain Tian Tap [virus growth factor, VGF] (Mus musculus) PubMed
2035.
data suggest that correct temporal expression of the VV I7L cysteine proteinase is required for core protein maturation, virion assembly and production of infectious progeny [I7L] (Mus musculus) PubMed
2036.
H2 and A28 are the only proteins presently known to be specifically required for vaccinia virus entry and are likely components of a fusion complex. (H2 protein) (Mus musculus) PubMed
2037.
required for vaccinia virion morphogeneis (J1R protein) (Mus musculus) PubMed
2038.
important role of E3L in vaccinia virus pathogenesis involves modulating expression of host cellular genes at the transcriptional level [E3L] (Mus musculus) PubMed
2039.
mapped complement control protein domains of VCP important for its cofactor activities, decay-accelerating activities & binding to target proteins; results show the entire length of the protein is required for VCP's various functional activities [VCP] (Mus musculus) PubMed
2040.
Vaccinia virus F1L expression during infection inhibits apoptosis and interferes with the activation of Bak. (F1L) (Mus musculus) PubMed
2041.
results suggest that protein disulphide isomerases may be involved in reorganization of disulfide bonds within the L1R protein [L1R] (Mus musculus) PubMed
2042.
Atherosclerosis was induced by a high-fat diet, and Vaccinia virus complement control protein was injected once per week after 8 weeks, leading to a reduction of athersclerosis [Vaccinia virus complement control protein] (Mus musculus) PubMed
2043.
Vaccinia virus F1L uses a specific, BH3-like domain to bind and inhibit Bak at the mitochondria. (F1L) (Mus musculus) PubMed
2044.
Two vaccinia open reading frames were confirmed as being expressed as novel proteins: E6R and L3L. [E6R, L3L] (Mus musculus) PubMed
2045.
The model supports biochemical evidence that VP39 functions as a processivity factor by partially enclosing the RNA primer at the heterodimer interface.[polyadenylate polymerase] (Mus musculus) PubMed
2046.
B14 is an intracellular protein that is non-essential for virus replication in cell culture but contributes to virus virulence in vivo and affects the host response to infection. [B14] (Mus musculus) PubMed
2047.
Vaccinia virus kelch protein A55 affects virus cytopathic effect in cell culture and virulence in murine intradermal infection model [A55] (Mus musculus) PubMed
2048.
our results provide direct evidence that G3L is an essential component of the vaccinia virus fusion complex [G3L] (Mus musculus) PubMed
2049.
In 293T cells, VV apparently utilizes its M2L protein to interfere with a step (s) that would otherwise enable ERK2 phosphorylation and the consequential activation of an NF-kappaBeta response. [M2L] (Mus musculus) PubMed
2050.
These results point to the transmembrane domain of B5 as the major determinant of the A33-B5 interaction and demonstrate that protein-protein interactions are crucial in determining the composition of the virus envelope. [A33, B5] (Mus musculus) PubMed
2051.
despite the structural relationships of L1 and F9, the two proteins have distinct functions in assembly and entry, respectively[L1 and F9] (Mus musculus) PubMed
2052.
G9 is the sixth that has been shown to be required for entry and membrane fusion[ G9 protein] (Mus musculus) PubMed
2053.
Deletions in the Z-DNA- or dsRNA-binding domains of E3L led to activation of signal transduction cascades and up-regulation of host gene expression, with many genes involved in the inflammatory response.[E3L] (Mus musculus) PubMed
2054.
Multimerization of D5 protein (ATpase) and enzymatic activity are necessary to support DNA replication. [D5] (Mus musculus) PubMed
2055.
This is the first structure of a virus-encoded tumour necrosis factor receptor (TNFR).[CrmE] (Mus musculus) PubMed
2056.
The crystal structure of the complex between Fab-7D11 and L1 reveals the basis for the conformation-specific binding as recognition of a discontinuous epitope containing two loops that are held together by a disulfide bond. [L1 protein] (Mus musculus) PubMed
2057.
purified recombinant VACV D9 fusion protein also decaps mRNA and that this activity was abolished by point mutations in the Nudix hydrolase motif.[D9] (Mus musculus) PubMed
2058.
vaccinia virus mRNA cap N7 methyl-transferase was originally an RNA cap 2'O-MT that has evolved to a catalytically inactive form retained for D1 stabilisation and MT activity enhancement through an allosteric mechanism [mRNA cap N7 methyl-transferase] (Mus musculus) PubMed
2059.
G6R protein, a member of the NlpC/P60 superfamily, in involved in virulence in mice but not replication in cell culture. [G6R] (Mus musculus) PubMed
2060.
a new function for VCP that may be important for poxvirus pathogenesis and impact immune responses to VACV-based vaccines [complement control protein (VCP)] (Mus musculus) PubMed
2061.
The 68k ankyrin-like protein (68k-ank)interacts with S-phase kinase-associated protein 1a (Skp1a), a part of the SCF ubiquitin ligase complex and co-immunoprecipitated with components of the endogenous, mammalian SCF ubiquitin ligase. [68k-ank] (Mus musculus) PubMed
2062.
Results identify a new vaccinia IMV envelope protein, WR53.5, that mediates cell adhesion and is important for virus virulence in vivo [WR53.5]. (Mus musculus) PubMed
2063.
The SPI-3/A56 complex on the infected cell surface therefore appears to reduce the entry of virions into infected cells.[A56] (Mus musculus) PubMed
2064.
These data indicate that C16 diminishes the immune response and is an intracellular immunomodulator. [C16] (Mus musculus) PubMed
2065.
Vaccinia virus L1 binds to cell surfaces and blocks virus binding and entry independently of glycosaminoglycans (Mus musculus) PubMed
2066.
the dimeric quaternary structure of VH1 is essential for specific recognition of activated STAT1, which prevents its nuclear translocation, thus blocking interferon-gamma signal transduction and antiviral response [VH1] (Mus musculus) PubMed
2067.
A34 is required to recruit B5 into the extracellular enveloped virus (EEV) membrane and B5 acts as a molecular switch to control EEV membrane rupture upon exposure to glycosaminoglycans.[B5] (Mus musculus) PubMed
2068.
68-kDa ankyrin-like protein is an essential factor for DNA replication and completion of the MVA intracellular life cycle. [68k-ank] (Mus musculus) PubMed
2069.
our data show that variola virus IL-18BP prevents IL-18 from binding to IL-18R by interacting with three residues that are part of the binding site for hIL-18Ralpha. [IL-18 binding protein] (Mus musculus) PubMed
2070.
Smallpox inhibitor of complement enzymes is a virulence factor that binds to a variety of cell types and inhibits complement activation at the C3 convertase step with equal or greater efficiency than that of the related host regulators. [SPICE] (Mus musculus) PubMed
2071.
Elimination of three heparin binding sites of SPICE protein severely decreases but does not eliminate glycosaminoglycan binding; complement regulatory sites overlap with each of the three heparin binding motifs. [SPICE protein] (Mus musculus) PubMed
2072.
Cleavage by resolvase was also tightly coupled at symmetrical positions across the junction, and coupling required the complete Holliday junction structure[ resolvase] (Mus musculus) PubMed
2073.
upregulation of these classic macrophage-related proinflammatory cytokine markers following infection of myeloid cells with the M141-knockout MYXV is mediated via the rapid activation of the cellular NF-kappaB pathway.[M141] (Mus musculus) PubMed
2074.
The authors report that M-T5 can bind Akt and the host SCF complex (via Skp1) simultaneously in myxoma virus-infected cells. (Mus musculus) PubMed
2075.
Results report the crystal structure of a viral FLIP, MC159, at 1.2 Angstroms resolution [MC159]. (Mus musculus) PubMed
2076.
Transgenic expression of viral FLIP MC159 specifically blocks apoptosis and programmed necrosis induced by multiple death receptors but does not interfere with other essential lymphocyte functions [MC159] (Mus musculus) PubMed
2077.
The MC160 protein of Molluscum contagiosum virus utilizes at least two distinct mechanisms for impeding NF-kappaB activation, association with Hsp90 to result in IKK1 protein degradation or interaction with procaspase-8.[MC160] (Mus musculus) PubMed
2078.
proteomic studies show an association of ICP27 with the cellular translation initiation factors poly A binding protein, eukaryotic initiation factor 3, and eukaryotic initiation factor 4G in infected cells [ICP27] (Mus musculus) PubMed
2079.
The direct interaction in vitro and in infected cells of ICP27 and ICP8. (Mus musculus) PubMed
2080.
regulates eIF-2alpha phosphorylation and antagonizes PKR and PERK during productive infections [gamma(1)34.5 protein] (Mus musculus) PubMed
2081.
cloning, sequencing, and characterization of a transcript immediately upstream of latency associated transcript; designated UOL [UOL] (Mus musculus) PubMed
2082.
Herpes simplex virus type 1 (HSV-1) protein ICP27 interacts with the cellular export adaptor protein Aly/REF and the viral RNAs to which it binds are exported via the TAP/NXF1 export receptor.[ICP27] (Mus musculus) PubMed
2083.
found that ICP27 enhances VP16 expression primarily by increasing the translational efficiency of VP16 mRNA [ICP27] [VP16] (Mus musculus) PubMed
2084.
nucleolar localization of the viral protein ICP0 of herpes simplex virus type 1. (ICP0} (Mus musculus) PubMed
2085.
requirement of ICP22 and the U(L)13 protein kinase in the posttranslational modification of RNA POL II (ICP22) (Mus musculus) PubMed
2086.
REVIEW: ICP27 functions primarily at the post-transcriptional level in inhibiting precursor mRNA splicing and in promoting nuclear export of viral transcripts [ICP27] (Mus musculus) PubMed
2087.
This prostein accumulates in cells infected with the mutant lacking the gene encoding ICP22 mediated the phosphorylation of histone deacetylase. (ICP22) (Mus musculus) PubMed
2088.
These results indicate that the protein kinase activity of UL13 plays a role in viral replication in cell culture, but the activity is not essential for the optimal expression of UL41 and ICP0 [ICP0] (Mus musculus) PubMed
2089.
triplet repeats in the central domain of the gamma134.5 protein of Herpes simplex virus 1 facilitate virus egress [gamma134.5 protein] (Mus musculus) PubMed
2090.
baculovirus antiapoptosis gene can efficiently substitute for the LAT in enhancing the HSV-1 reactivation phenotype (Mus musculus) PubMed
2091.
ICP0 targets USP7 for ubiquitination and proteasome-dependent degradation; concluded that USP7-mediated stabilization of ICP0 is dominant over ICP0-induced degradation of USP7 during productive HSV-1 infection [ICPO] (Mus musculus) PubMed
2092.
a function encoded by the LAT gene increases the amount of dimethyl lysine 9 form of histone H3 or heterochromatin and reduces the amount of dimethyl lysine 4 form of histone H3 on viral lytic-gene promoters.(latency-associated transcript gene product) (Mus musculus) PubMed
2093.
(latency-associated transcript) locus regulates the frequency of encephalitis in male or female mice. (Latency associated protein) (Mus musculus) PubMed
2094.
Data show that the formation of superhelical ICP8-single stranded DNA filaments is required for annealing [ICP8]. (Mus musculus) PubMed
2095.
observed that a decrease in both latency-associated transcript (LAT) enhancer histone H3 acetylation and LAT RNA abundance occurs prior to an increase in acetylation, or transcriptional permissiveness, at the ICP0 promoter [LAT, ICP0] (Mus musculus) PubMed
2096.
VP16 was acquired prior to primary envelopment of the virus at the inner nuclear membrane [VP16] (Mus musculus) PubMed
2097.
findings show that a function of the stable 2-kb LAT intron is to protect cells from cold-induced stress and that this may be mediated via Hsp70 [LAT] (Mus musculus) PubMed
2098.
complement ICP0- viruses may lead to the identification of cellular activities that are important for reactivation from neuronal latency [ ICP0] (Mus musculus) PubMed
2099.
VP16 and ICP0 stimulate viral gene expression at least in part by counteracting this innate antiviral defence mechanism.[VP16, ICP0] (Mus musculus) PubMed
2100.
U(S)3 protein kinase blocks histone deacetylation by a mechanism distinct from that of ICP0.(ICP0) (Mus musculus) PubMed
2101.
Promyelocytic leukemia protein contributes to a cellular antiviral repression mechanism that is countered by the activity of ICP0. (Mus musculus) PubMed
2102.
The nucleocytoplasmic distribution of the LAT (latency-associated transcripts) exon RNA and its related function may be influenced by the differentiation state of cells. [LAT] (Mus musculus) PubMed
2103.
LATs might be involved in the maintenance of HSV-1 latency through the posttranscriptional regulation of ICP0 in order to inhibit expression of this potent activator of gene expression during latency [ICP0] (Mus musculus) PubMed
2104.
findings provide new data demonstrating that anterior corneal keratocytes become infected and express ICP0 during acute HSV-1 infection (Mus musculus) PubMed
2105.
virion-specific differences in ICP22- viruses add a new level of complexity to the functional analysis of this immediate-early viral regulatory protein [ICP22] (Mus musculus) PubMed
2106.
data indicate that the regulation of expression and processing of LAT RNA within the mouse is highly cell-type specific and occurs in the absence of other viral cis- and trans-acting factors [LAT] (Mus musculus) PubMed
2107.
ICP27 is essential for IEX-1 mRNA stabilization whereas virion host shut plays little if any role[ICP27] (Mus musculus) PubMed
2108.
HSV-1 LAT decreases the level of CGRP in trigeminal neurons [LAT PROTEIN, HSV1] (Mus musculus) PubMed
2109.
DNA ligase IV/XRCC4 serves an important role in the replication cycle of herpes viruses [DNA ligase IV and XRCC4 ] (Mus musculus) PubMed
2110.
the highly concentrated LANA-1, anchored to the host genome in the nuclear foci of latently infected cells and replicated through each cell generation, may function as "epigenetic modifier" (Mus musculus) PubMed
2111.
the N terminus of VP5 and the alpha helices embedded in this domain, as in the capsid shell proteins of some double-stranded DNA phages, are a key regulator of shell accretion and stabilization.[VP5] (Mus musculus) PubMed
2112.
LAT blocks two biochemical hallmarks of apoptosis, caspase 3 cleavage and DNA laddering, in the absence of other HSV-1 gene products.[LAT] (Mus musculus) PubMed
2113.
The results show that the cytoplasmic localization of ICP0 and ICP4 is a prerequisite for the assembly of these proteins into viral particles and ICP27 plays a role in determining the composition of HSV-1 virions.[ICP27, ICP0, ICP4] (Mus musculus) PubMed
2114.
Study confirms that ICP27 stimulates translation of VP16 mRNA as well as an additional HSV-1 late ICP5 mRNA.[ICP27] (Mus musculus) PubMed
2115.
Viral immediate-early protein ICP27 plays a role in inhibiting interferon I signaling by downregulating STAT-1 phosphorylation and in preventing the accumulation of STAT-1 in the nucleus. [ICP27] (Mus musculus) PubMed
2116.
2 LAT-specific small RNAs in the first 1.5 kb of LAT (apoptosis-inhibiting region). They have extensive secondary structure & a stem-loop structure & can base pair with the ICP4 mRNA. They may play a role in the latency-reactivation cycle. LAT. (Mus musculus) PubMed
2117.
Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16.[ICP6 protein, HSV] (Mus musculus) PubMed
2118.
nuclear localization signal may be involved in transport of VP1-2 early in infection or to late assembly sites within the nucleus or, considering the potential existence of VP1-2 cleavage products[VP1-2] (Mus musculus) PubMed
2119.
Based on these results, the authors conclude that ICP27 has two distinct effects on the transfected gC gene: it (i) stimulates mRNA accumulation and (ii) promotes the retention of an intron.[ICP27] (Mus musculus) PubMed
2120.
Herpes simplex virus-1 infected cell protein 27 (HSV-1 ICP27), represses NF-kappaB activity through binding to inhibitor of kappaB (IkappaBalpha), blocking phosphorylation and ubiquitination of IkappaBalpha, and stabilizing IkappaBalpha (ICP27). (Mus musculus) PubMed
2121.
HSV-1 expresses at least two primary miRNA precursors (from LAT) in latently infected neurons that may facilitate the establishment and maintenance of viral latency by post-transcriptionally regulating viral gene expression[LAT] (Mus musculus) PubMed
2122.
have implications on the role of base excision repair in viral genome maintenance during lytic replication and reactivation from latency[ 5'-deoxyribose phosphate lyase] (Mus musculus) PubMed
2123.
Induction of cellular stress overcomes the requirement of herpes simplex virus type 1 for immediate-early protein ICP0 and reactivates expression from quiescent viral genomes. (ICP0) (Mus musculus) PubMed
2124.
study provides evidence that ICP0 directly alters the chromatin structure of the HSV-1 genome during lytic infection [ICP0] (Mus musculus) PubMed
2125.
an HSV-1 LAT(-) mutant that expresses cellular FLICE-like inhibitory protein under control of the LAT promoter and in place of LAT nucleotides 76 to 1667 had a reactivation phenotype similar to wild-type virus [FLIP and LAT genes] (Mus musculus) PubMed
2126.
control of TBK1-mediated cell signaling by the gamma(1)34.5 protein contributes to herpes simplex virus infection[ gamma134.5 protein ] (Mus musculus) PubMed
2127.
Using chemical inhibitors, the authors show that the ICP27-mediated activation of p38 signaling is responsible for the observed induction of apoptosis in the induced cell lines.[ICP27] (Mus musculus) PubMed
2128.
The authors demonstrate that mitochondrial localization of UL12.5 relies largely on sequences located between UL12 residues 185 and 245 (UL12.5 residues 59 to 119).[UL12.5] (Mus musculus) PubMed
2129.
Electron microscopic image reconstruction reveals that the ICP8 filaments are bipolar, with an asymmetric unit containing two subunits of ICP8 that constitute a symmetrical dimer. (Mus musculus) PubMed
2130.
gamma 34.5 is involved in the impairment of innate immunity by inhibiting both type I interferon production and dendritic cell maturation. [gamma 34.5] (Mus musculus) PubMed
2131.
Glycoprotein E is dispensable for retrograde axonal transport; however, it promotes HSV-1 spread from epithelial cells to neurites. [Glycoprotein E] (Mus musculus) PubMed
2132.
arginine methylation of the ICP27 RGG box regulates its export activity (Mus musculus) PubMed
2133.
LAT modulate latent infection in mouse trigeminal ganglia. [LAT] (Mus musculus) PubMed
2134.
These results indicate that ICP27 RGG box methylation regulates interaction ALY and SRPK1 proteins. (Mus musculus) PubMed
2135.
expression of two LAT sRNAs plays a role in the latency-reactivation cycle by inhibiting apoptosis and productive infection[LAT] (Mus musculus) PubMed
The authors show that eIF2alpha dephosphorylation by gamma(1)34.5 is crucial for viral neuroinvasion.[gamma(1)34.5] (Mus musculus) PubMed
2138.
results demonstrate that phosphorylation of HSV-2 VP22 at multiple serine residues is induced by UL13 and cellular kinase(s); distribution of VP22 is independent of its phosphorylation status but is controlled indirectly by UL13 kinase activity [VP22] (Mus musculus) PubMed
2139.
ICP10 gene expression is sufficient to induce apoptosis in Jurkat cells, while its expression protects epithelial HEp-2 cells from apoptosis triggered by cycloheximide and tumor necrosis factor alpha.[ICP10] (Mus musculus) PubMed
2140.
Interactions between the LR fusion protein and C/EBP-alpha promote the establishment of latency. [LR gene (ORF1&ORF2 fusion)] (Mus musculus) PubMed
2141.
The authors demonstrated that an LR-encoded protein, open reading frame 2 (ORF-2), or ORF-2 fusion proteins encoded by alternatively spliced LR transcripts inhibit cold shock or Fas ligand-induced apoptosis in mouse neuroblastoma (neuro-2A) cells.[ORF-2] (Mus musculus) PubMed
2142.
The study demonstrated that BICP27 is a nucleolar protein, adding BICP27 to the growing list of transactivators which localize to the nucleolus.[BICP27] (Mus musculus) PubMed
2143.
required for efficient virus growth in vitro and the carboxy-terminal amino acids are not required for its function [glycoprotein K] (Mus musculus) PubMed
2144.
Results support our hypothesis that the EICP27 protein participates in the trans-activation of EHV-1 promoters, and suggest its presence within RNA polymerase II preinitiation complexes that assemble at viral promoters.[EICP27, IE protein] (Mus musculus) PubMed
2145.
Expression of full-length gp2 is sufficient to restore full respiratory virulence to the attenuated KyA strain. (gp2 protein) (Mus musculus) PubMed
2146.
ETIF has an essential function in the replication cycle of EHV-1, and its main role appears to be in secondary envelopment [ETIF] (Mus musculus) PubMed
2147.
IR2 downregulates EHV-1 gene expression by blocking immediate-early protein binding to viral promoters and/or squelching the limited supplies of transcription factors TFIIB and TATA box-binding protein. (IR2) (Mus musculus) PubMed
2148.
description of the discovery of a second hybrid gene found in EHV-1 defective interfering particles but not in the standard virus; the new Hyb gene (Hyb2.0) contains 684 bp (5') of the IR4 ORF fused to 45 bp from the 3'portion of the UL5 gene[Hyb2.0] (Mus musculus) PubMed
2149.
The possible role of the IR3 transcript in EHV-1 infection is discussed [IR3& IE] (Mus musculus) PubMed
2150.
in contrast to the highly pathogenic parent virus, the IR4 deletion mutant failed to cause disease in the CBA mouse as judged by assessing body weight and clinical signs and was unable to replicate in the murine lung.[IR4] (Mus musculus) PubMed
2151.
Transfection of cells with a plasmid expressing ORF63 but lacking the putative nuclear localization signal of the protein resulted in increased expression of the protein in the cytoplasm, ORF63 protein) (Mus musculus) PubMed
2152.
IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity [IE63] (Mus musculus) PubMed
2153.
IE63was able to downregulate the expression of reporter genes under the control of heterologous promoters, indicating that this viral factor can be involved in the VZV-mediated delayed host shutoff [IE63] (Mus musculus) PubMed
2154.
results indicate that IE62 nuclear import is modulated as a result of direct phosphorylation of IE62 by ORF66 kinase [IE62, ORF66 kinase ] (Mus musculus) PubMed
2155.
IE62 forms a complex with ORF9 protein in the cytoplasm at late times in infection. [IE62] (Mus musculus) PubMed
2156.
findings show that the IE63 protein increases the release of CGRP from trigeminal neurons [IE63] (Mus musculus) PubMed
2157.
IE63 affected transcription of a small number of cellular genes. It interfered with the TNF-inducibility of several NF-kappaB dependent genes by the accelerated resynthesis of the inhibitor IkappaBalpha. IE63. (Mus musculus) PubMed
2158.
IE62 activation domain appears to selectively interact with a form of the Mediator complex lacking CDK8[ IE62 ] (Mus musculus) PubMed
2159.
The transcriptional activation domain of IE62 directly with aa 402 to 590 of the MED25 subunit of the human mediator complex. (Mus musculus) PubMed
2160.
CMV IE1 protein induces RelB NF-kappaB subunit via activation of JNK and AP-1 [CMV IE1 protein] (Mus musculus) PubMed
2161.
results show that IE1(491aa) is composed of at least two domains that support replication, a region that complements ie1 mutant virus replication to low levels and an acidic domain that dramatically enhances complementation [IE1491aa] (Mus musculus) PubMed
2162.
pp71 provokes slow reactivation of quiescent genomes, in conjunction with cell survival, represents a novel property for a viral structural protein [pp71] (Mus musculus) PubMed
determined UL144 polymorphisms of HCMV strains from amniotic fluid of infected fetuses & compared them to strains from viremic adults; all five UL144 genotypes could be transmitted from mothers to fetuses & could cause congenital infection [UL144] (Mus musculus) PubMed
2165.
Evasion of NK cell killing was mediated by human cytomegalovirus UL141 blocking surface expression of CD155 [UL141] (Mus musculus) PubMed
2166.
UL142 is a novel HCMV-encoded MHC class I-related molecule (UL142) (Mus musculus) PubMed
2167.
glycoprotein M/gN can elicit a virus-neutralizing antibody response in humans infected with human cytomegalovirus [glycoprotein N] (Mus musculus) PubMed
2168.
UL80a amino-conserved domain involved in early steps of capsid assembly pathway. [UL80a] (Mus musculus) PubMed
2169.
pp28 must accumulate in the assembly compartment for efficient envelopment of the particle; it has a role in the late stages of assembly, such as envelopment (Mus musculus) PubMed
2170.
pUL50 AND pUL53 protein ate involved in the recruitment of protein kinase C, which is important for cytomegalovirus-induced distortion of the nuclear lamina.[pUL50 AND pUL53] (Mus musculus) PubMed
2171.
These results suggest that pUL50 and pUL53 may play an important role in the exit of virions from the nucleus by inducing structural modifications of the nuclear lamina. {UL50, UL53] (Mus musculus) PubMed
2172.
These results suggest that HCMV subverts innate immunity by suppressing type I IFN production of plasmacytoid dendritic cells during primary viral infection via its IL-10 homolog.[IL-10] (Mus musculus) PubMed
2173.
results argue that the UL29/28 locus contributes to activation of immediate-early gene expression [UL28; UL29] (Mus musculus) PubMed
2174.
may contribute to oncogenesis through its ability to promote cell survival by repressing TGF-beta signaling [K-bZIP] (Mus musculus) PubMed
2175.
results reveal a particular feature of the transmembrane domain of tumor-derived CAO-LMP1 and suggest its possible contribution to the pathogenesis of nasopharyngeal carcinoma (Mus musculus) PubMed
2176.
a tegument protein of the EBV homologous to VP16 of HSV1 and ORF22 of Varicella zoster virus. [BPLF1] (Mus musculus) PubMed
2177.
regulation of LMP1 on the nuclear translocation of EGFR is critical for the process of nasopharyngeal carcinoma (Mus musculus) PubMed
2178.
may directly engage signaling pathways to influence epithelial cell behavior such as cell adhesion and motility. [LMP2B] (Mus musculus) PubMed
2179.
isolated and sequenced complete EBV LMP1 genes from 12 biopsy samples of salivary gland lymphoepithelial carcinoma (latent membrane protein 1) (Mus musculus) PubMed
2180.
EBNA-LP strongly coactivated EBNA2 stimulation of LMP-1 and LMP2B RNAs, which are expressed from the viral divergent promoter. [LMP-1][LMP2B][EBNA-LP] (Mus musculus) PubMed
2181.
Deletion of the entire EBNA-3B open reading frame from the EBV BAC had no adverse impact on growth of EBV-immortalized B cells, providing formal proof that EBNA-3B is not essential for EBV-mediated B-cell growth transformation in vitro. [EBNA-3B] (Mus musculus) PubMed
2182.
LMP1-induced tyrosine phosphorylation of STAT1 is almost exclusively due to the NF-kappaB-dependent secretion of interferons in B cells.[LMP1] (Mus musculus) PubMed
2183.
An association of the LMP1 cytoplasmic carboxyl terminus with caspase-8 by a heterodimerizing agent causes apoptosis. [LMP1--latent membrane protein 1] (Mus musculus) PubMed
2184.
activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186 [BZLF1, BRLF1] (Mus musculus) PubMed
2185.
diseases share a common signal pathway, through either the mutation or LMP1-mediated suppression of the SH2 domain protein 1A, Duncan's disease gene [LMP1] (Mus musculus) PubMed
2186.
LMP1-mediated rodent fibroblast transformation is dependent upon activation of PI3K and Akt and is independent of activation of NF-kappaB [LMP1] (Mus musculus) PubMed
2187.
gp350/220 is involved in Epstein-Barr virus invasion of host cells [gp350/220] (Mus musculus) PubMed
2188.
EBNA-LP interacts with the promyelocytic leukemia nuclear body (PML NB)-associated protein Sp100 and displaces Sp100 and heterochromatin protein 1alpha (HP1alpha) from PML NBs. (Mus musculus) PubMed
2189.
EB2 is essential for the nuclear export of most, but not all, late mRNAs produced from intronless genes. (EB2 protein) (Mus musculus) PubMed
cloning, overexpression and purification of a C-terminal fragment of ZEBRA that encompasses the bZIP domain and its crystallization in complex with a DNA duplex[ZEBRA protein] (Mus musculus) PubMed
2192.
EBNA3B co-localized with both EBNA3A & EBNA3C in nuclei of cells when overexpressed; identification of four potential nuclear-localization signals (NLSs); only two of the NLSs were found to be functional in the context of the full-length EBNA3B[EBNA3B] (Mus musculus) PubMed
2193.
lyLMP-1 functions as a posttranslational negative regulator of LMP-1 oncogenesis.(lyLMP-1) (Mus musculus) PubMed
2194.
The identification of 6 functional nuclear localization signals in the Epstein-Barr nuclear antigen 3A (EBNA3A) is reported. [EBNA3A] (Mus musculus) PubMed
2195.
reveal distinct functional requirements for gH/gL and gp42 complexes in Epstein-Barr virus-mediated membrane fusion [gH and gL] (Mus musculus) PubMed
2196.
antibodies to gp350/220 enhance infection of epithelial cells (Mus musculus) PubMed
2197.
stronger DNA binding is required for ZEBRA to activate replication than that required to activate transcription[ZEBRA] (Mus musculus) PubMed
2198.
The A157154C mutation in A73 gene might be correlated to the occurrence and development of nasopharyngeal carcinoma. (Mus musculus) PubMed
2199.
In vitro methylation blocked binding of the cellular proteins c-Myc and ATF to the 5'-region of the EBER-1 gene, and silenced the expression of the EBER-1 and EBER-2 genes, transcribed by RNA polymerase III, in transfected cells.[EBER-1] (Mus musculus) PubMed
2200.
Glycoprotein B is required for cell fusion in epithelial adn B cells. [gB] (Mus musculus) PubMed
2201.
Growth-promoting properties of Epstein-Barr virus EBER-1 RNA correlate with ribosomal protein L22 binding [EBER1] (Mus musculus) PubMed
2202.
These results indicate that herpesvirus saimiri utilizes the ORF 57 protein to recruit components of the exon junction complex and subsequently TAP to promote viral RNA export through the cellular mRNA export pathway. [ORF 57] (Mus musculus) PubMed
2203.
data demonstrate that growth transformation by herpesvirus saimiri depends on a complex interaction of Tip with the T-cell tyrosine kinase Lck [Tip] (Mus musculus) PubMed
2204.
Expression of the ORF57 protein induces nucleolar redistribution of human TREX (transcription/export) proteins that are involved in mRNA nuclear export. (ORF 57) (Mus musculus) PubMed
2205.
Tip LBD1 binding did not cause gross structural changes in Lck SH3 but globally stabilized the domain and reduced the rate of partial unfolding by a factor of five. (Mus musculus) PubMed
2206.
findings show that association between ORF73 and MeCP2 is essential for HVS chromosomal attachment and episomal persistence.[Orf73] (Mus musculus) PubMed
2207.
viral oncoproteins saimiri transformation-associated protein of subgroup C induces NF-kappaB activation (Mus musculus) PubMed
2208.
manipulation of the repeat revealed that the motif EEAEEAEEE was sufficient to cause a reduction in recognition of ORF73 by CD8(+) cytotoxic T lymphocytes. (Mus musculus) PubMed
These data suggest that the GAAGRG motif may be required within a HVS intronless mRNA for recognition by the ORF57 protein. [ORF57 protein] (Mus musculus) PubMed
2211.
The authors demonstrate that ORF57 recruits several members of hTREX, namely Aly, UAP56 and hTHO-complex proteins, onto the viral mRNAs to assemble an export-competent ribonucleoprotein particle. (Mus musculus) PubMed
2212.
activation of p38 MAPK and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and TNFR1/TNFa expression [pX, hepatitis B virus] (Mus musculus) PubMed
2213.
hepatitis B virus M protein has an autoregulatory function on surface gene expression [M protein] (Mus musculus) PubMed
2214.
determination of minimal distance between the matrix and transmembrane domains of the large hepatitis B virus envelope protein [envelope protein L] (Mus musculus) PubMed
2215.
The HBxAg is associated with decreased expression of E-cadherin, accumulation of beta-catenin in the cytoplasm and nucleus, and increased cell migration, which may contribute importantly to hepatocarcinogenesis.[HBxAg] (Mus musculus) PubMed
2216.
mRNA differential display analysis of the role of hepatitis B virus HBx and MHBs in hepatocellular carcinoma [MHBs] (Mus musculus) PubMed
2217.
Efficiently cleaves target mRNA at specific sites in vitro (10-23 DNA enzyme) (Mus musculus) PubMed
2218.
Hepatitis B e antigen (HBeAg) status can be used with caution in selected recipients without significantly affecting graft and patient outcome.(HbeAg) (Mus musculus) PubMed
2219.
A higher prevalence of pre-S deletion was found in carriers with progressive liver diseases compared with HBV chronic carriers. (pre-S1 protein, pre-S2 protein, HBV) (Mus musculus) PubMed
2220.
protein kinase A facilitates hepatitis B virus(HBV) core assembly through phosphorylation of the HBV capsid proteins at Ser87 [Capsid Proteins] (Mus musculus) PubMed
2221.
HBx mutant that did not interact with cyclin E/A failed to destabilize p27(Kip1) or deregulate the cell cycle. (HBx protein) (Mus musculus) PubMed
2222.
findings demonstrate that the C-terminal region of pre-S1 and a putative translocation motif in pre-S2 are not necessary for HDV infectivity and, by inference, are not needed for HBV attachment and entry into susceptible cells [L protein] (Mus musculus) PubMed
2223.
the presence of precore/core promoter mutations was associated with fulminant hepatitis, severe coagulopathy and mortality [HBeAg; Hepatitis B envelope antigen] (Mus musculus) PubMed
2224.
The post-translational modification of the large L envelope protein by N-glycosylation is reported.[L protein] (Mus musculus) PubMed
2225.
These results establish that unlike HBx, MHBs(t) enhances TRAIL-induced hepatocyte apoptosis through a novel mechanism that involves ERK2. (Mus musculus) PubMed
2226.
A new mutation pattern in HBV reverse transcriptase, A181S+M2041, arising under lamivudine treatment confers cross-resistance to adefovir dipivoxil both in vivo and in vitro. (Mus musculus) PubMed
2227.
HBx deletion, especially the COOH-terminal deletion of HBx is a frequent event in HBV-associated HCC tissues in China. Deletion and probably integrated forms of the HBx gene may be implicated in liver carcinogenesis [HBx]. (Mus musculus) PubMed
2228.
Results indicate that HBSP interacts with Bcl-2/Bcl-xl in vitro and induces apoptosis in HepG2 cells [HBSP]. (Mus musculus) PubMed
2229.
Both replication and gene expression of HBV require functional CREB and HBV-CRE. CRE decoy oligonucleotides and overexpression of CREB mutants can effectively block HBV life cycle. Interventions against CREB could be new way to treat HBV infection. (Mus musculus) PubMed
2230.
The structural properties of dimeric HBc, as well as its dynamics and intermolecular interactions were characterised, at atomic resolution.[Hbc] (Mus musculus) PubMed
2231.
The study reveals genotypic differences in HBeAg processing and implicates furin as the major enzyme involved in the cleavage of the first and second RXXR motifs. (Mus musculus) PubMed
2232.
These results demonstrate that group II NPV F proteins can be functionally replaced with a homologue of other group II NPVs, suggesting that the interaction of F with other viral or host proteins is not absolutely species-specific. [F protein] (Mus musculus) PubMed
2233.
molecular analysis of Helicoverpa zea CYP6B8 and CYP321A1 [CYP6B8, CYP321A1] (Mus musculus) PubMed
2234.
DNA polymerase X binds the ssDNA without detectable cooperativity and with very modest base specificity[DNA polymerase X ] (Mus musculus) PubMed
2235.
Results discuss interactions of the DNA polymerase X of African swine fever virus with double-stranded DNA, and describe the functional structure of the complex [DNA polymerase X]. (Mus musculus) PubMed
2236.
the specific structure necessary to recognize the short gaps is induced by magnesium binding to the enzyme. In the absence of Mg+2, pol X looses its selectivity for short ssDNA gaps.[DNA polymerase X] (Mus musculus) PubMed
2237.
Heterogeneous nuclear ribonucleoprotein K was identified as interacting cellular protein with the abundant immediate early protein p30 from African swine fever virus in a macrophage cDNA library screening. (p30) (Mus musculus) PubMed
2238.
These results agree well with kinetic data for pol X and provide a structural/dynamic basis to explain, at atomic level, the fidelity of this polymerase compared with other members of the X family.[DNA polymerase X] (Mus musculus) PubMed
2239.
DNA polymerase x fidelity is altered by the redox state of the enzyme and its related conformational changes[DNA POLYMERASE X] (Mus musculus) PubMed
2240.
The authors show that recombinant ASFV g5Rp hydrolyzes the mRNA cap when tethered to an RNA moiety, liberating m(7)GDP as a product.[g5Rp] (Mus musculus) PubMed
2241.
E5 from both BPV-1 and BPV-4 disturbs the actin cytoskeleton and focal adhesions in transformed bovine cells [E5] (Mus musculus) PubMed
2242.
E5 is a player in the transformation of equine cells and the induction of sarcoids, and a potential major cause of MHC I downregulation and hence poor immune clearance of tumour cells. [E5] (Mus musculus) PubMed
2243.
NEW ENTRY human papillomavirus E7 oncoprotein The E7 chaperone can stably bind model polypeptides and hold them in a state with significant tertiary structure, but does not bind the fully native proteins (Mus musculus) PubMed
2244.
Binding of E2 at the binding sites play an important role in overcoming inhibition of E1 complex formation caused by the binding of CDP to the origin of replication. (E2 protein, papillomavirus) (Mus musculus) PubMed
2245.
E6*I mRNAs of high-risk high-risk human papillomaviruses are responsible for E7 production [E7 oncoprotein] (Mus musculus) PubMed
2246.
evasion of apoptosis mediated by HPV-16 E6 and E7 is associated with increased Bcl-2 and decreased Bak in laryngeal carcinogenesis and the decreased level of Bak by E6 and E7 is caused by reducing its protein stability.[E6, E7] (Mus musculus) PubMed
2247.
We report here that the HPV1 E4 protein, in the presence of a soluble form of the replication-licensing factor (RLF) Cdc6, inhibits initiation of cellular DNA replication in a mammalian cell-free DNA replication system. [E4] (Mus musculus) PubMed
2248.
it is shown here for the first time that the HPV-18 and -45 E7 proteins can be detected in cervical carcinoma biopsies [E7] (Mus musculus) PubMed
2249.
these data suggest that HPV-45 E7 is a transforming protein and that abrogation of cell cycle control contributes to its oncogenic potential.[E7] (Mus musculus) PubMed
2250.
a fraction of P6 immunoprecipitates with DRB4 in CaMV-infected cells. (P6) (Mus musculus) PubMed
2251.
Three-dimensional structure of the R115E mutant 2'-deoxycytidylate deaminase suggests a hypothesis for activity of the mutant as a dimer, and a model for the mechanism for allosteric regulation of the wild-type enzyme. [2'-deoxycytidylate deaminase] (Mus musculus) PubMed
2252.
RNA ligase type 1 from bacteriophage T4 (Rnl1) is involved in countering a host defense mechanism by repairing 5'-PO4 and 3'-OH groups in tRNA(Lys). (T4 RNA ligase) (Mus musculus) PubMed
2253.
contribution of both MuA and DNA supercoiling to the 5-noded Mu synapse built at the 3-way junction [transposase MuA] (Mus musculus) PubMed
2254.
gp44 is an essential protein for baseplate assembly & forms a trimer comprising a complex consisting of 42 kDa & 40 kDa subunits that had been cleaved in C-terminal region. Thermodynamic analysis shows that C-terminal region forms a flexible domain[gp44] (Mus musculus) PubMed
2255.
Data show that gp44 exists as a trimer exhibiting a hub-like structure with an inner diameter of 25 angstroms through which DNA can presumably pass during infection [gp44]. (Mus musculus) PubMed
2256.
Bacteriophage Mu baseplate protein gene product 44 (gp44) crystsals diffract X-rays to at least 2.1 A resolution and are stable in the X-ray beam and are therefore appropriate for structure determination (gp44) (Mus musculus) PubMed
2257.
MuA assembles DNA hairpin substrates into a catalytically competent transpososome, open the hairpin ends and accurately join the opened ends to the target DNA (MuA). (Mus musculus) PubMed
2258.
A subset of the six subunits of MuA associated with their cognate sub-sites at L and R communicate with the enhancer to trigger the stepwise assembly of the functional transpososome (Mus musculus) PubMed
2259.
data prove the saccharidic nature of the bacterial receptor recognized by phage p2 and identify the position of its binding site in the RBP (receptor binding protein) head domain [RBP] (Mus musculus) PubMed
2260.
Crystal structure of a truncated version of protein gpD [gpD] (Mus musculus) PubMed
2261.
beta protein can catalyze steps that are central to both strand annealing and strand invasion pathways of recombination(beta protein) (Mus musculus) PubMed
2262.
NMR solution structure of the monomeric form of the bacteriophage lambda capsid stabilizing protein gpD [capsid protein gpD] (Mus musculus) PubMed
2263.
the N/boxB complex exists in a dynamical two-state equilibrium between stacked and unstacked conformations; the present work determines the nature of interactions responsible for this sequence-dependent behavior (Mus musculus) PubMed
2264.
provide direct experimental support for the long presumed cooperative assembly of gpNu1 and IHF at the cos sequence of lambda DNA [gpNu1] (Mus musculus) PubMed
2265.
Characterization of a previously unrecognized phosphodiesterase activity of lambda phosphatase (lambda phosphatase). (Mus musculus) PubMed
2266.
The X-ray structure of the bacteriophage SPP1 portal protein in its isolated 13-subunit form and the pseudoatomic structure of a 12-subunit assembly, is described.[Portal protein] (Mus musculus) PubMed
2267.
Results suggest that NusAE136K suppresses Nun-arrest when it is a component of the transcription elongation complex, perhaps, in part, by blocking interactions between the Nun C terminus and RNA polymerase and DNA. (Mus musculus) PubMed
2268.
We propose that RNase III processing site enhances the on-rate of Nun at nutL of lambda phage, stimulating Nun-mediated arrest in vitro.[Nun] (Mus musculus) PubMed
2269.
Coliphage HK022 Nun protein targets phage lambda nut boxB RNA and acts as a transcriptional terminator, counteracting the phage lambda N protein, a suppressor of transcription termination. [Nun protein] (Mus musculus) PubMed
2270.
gp26 is very likely a triple stranded coiled-coil protein [gp26] (Mus musculus) PubMed
2271.
Gp26 is phage P22-encoded tail accessory factor essential for stabilization of viral DNA in capsid. In solution, gp26 exists as extended triple-stranded coiled-coil protein sharing profound similarities with class I viral membrane-fusion protein[gp26] (Mus musculus) PubMed
2272.
In the P22 tail needle, the authors identified an 85-residue-long helical domain, termed MiCRU (minimal coiled-coil repeat unit), that can be inserted in-frame inside the gp26 helical core, preserving the straight morphology of the fiber. (Mus musculus) PubMed
2273.
The phi29 DNA polymerase thumb subdomain may be responsible for the coordination of polymerization and exonuclease activities (DNA polymerase). (Mus musculus) PubMed
2274.
The X-ray crystal structures of phi29 DNAP, a member of the protein-primed subgroup of the B-family of polymerases, complexed with primer-template DNA. [DNA polymerase] (Mus musculus) PubMed
2275.
Results revealed that protein p56 blocked the DNA-binding site of uracil-DNA glycosylase (UDG). Thus, protein p56 could mimic DNA structural features in order to inhibit UDG (p56). (Mus musculus) PubMed
2276.
protein p56 ensures an efficient viral DNA replication, preventing the deleterious effect caused by uracil-DNA glycosylase (UDG) when it eliminates uracil residues present in the phi29 genome[p56] (Mus musculus) PubMed
2277.
The helicase rate of stimulation depends upon the DNA synthesis rate and does not rely on specific interactions between T7 DNA polymerase and the carboxy-terminal residues of T7 helicase [T7 helicase gp4] (Mus musculus) PubMed
2278.
T7 RNA polymerase pausing signal within this critical DNA structure could interfere with normal regulation of RNA transcription. (RNA polymerase) (Mus musculus) PubMed
2279.
Ser substitution at position 102 affects the structural stability of thioredoxin resulting in a reduced binding affinity for gp5 and loss of processivity [gp5] (Mus musculus) PubMed
2280.
During bacteriophage T7 infection, the Escherichia coli RNA polymerase beta' subunit is phosphorylated by the phage-encoded kinase Gp0.7 (Mus musculus) PubMed
2281.
data show that the form of the complex between endonuclease I and a DNA junction depends on the core of the junction and on interactions with the first six base-pairs of the arms containing the 5' ends of the continuous strands [endonuclease I] (Mus musculus) PubMed
2282.
quaternary protein structure of gene 4 primase/helicase [gene 4] (Mus musculus) PubMed
2283.
Night-time restricted feeding altered oscillation of the peripheral clock and mPai-1 mRNA rhythm (PAI-1) (Mus musculus) PubMed
2284.
Required in mediating Notch signaling in the developing cardi(ac and vascular systems. (Hesr2) (Mus musculus) PubMed
2285.
NS2 required for efficient viral infection, but dispensable for SAAB (Smn-associated APAR (autonomous parvovirus-associated replication) bodies ) formation. [NS2] (Mus musculus) PubMed
2286.
NS2 was expressed at high ratios even in the absence of upstream mutations, and progeny accumulation was efficient. (ns2 protein) (Mus musculus) PubMed
2287.
findings suggest that the accumulated level of NS2 may play a larger role in the host ranges of the fibrotropic strain and the lymphotropic strain of minute virus of mice than previously appreciated [NS2] (Mus musculus) PubMed
2288.
the NS2P isoform, even when expressed at a level lower than that of NS2Y, performs a critical role in infection of A9 cells that cannot be accomplished by the NS2Y isoform alone [NS2] (Mus musculus) PubMed
2289.
LIF, cAMP signaling cascades,Myt1 play roles in the differentiation of oligodendrocytes through their action on the Opalin oligodendrocyte enhancer. (Mus musculus) PubMed
2290.
Silencing Cep120 in the developing neocortex impairs both interkinetic nuclear migration (INM), a characteristic pattern of nuclear movement in neural progenitors, and neural progenitor self-renewal. (Mus musculus) PubMed
2291.
A supraphysiological nuclear export signal in an endogenous protein, the NS2 protein of parvovirus Minute Virus of Mice (MVM), is identified.[NS2] (Mus musculus) PubMed
2292.
Blocking expression of the proline-rich 11-kDa protein significantly reduced B19 viral infectivity and expression of the 11-kDa protein was critical for VP2 capsid production and trafficking in infected cells. (11-kilodalton protein, human parvovirus B19) (Mus musculus) PubMed
2293.
we have identified a novel cellular AAV-2 Rep78/Rep68 interaction partner, KCTD5, located predominantly in the cytoplasm.[Rep78] (Mus musculus) PubMed
2294.
Mre11 repair complex (MRN) poses a barrier to AAV and that the helper function provided by E1b55K/E4orf6 involves MRN degradation.[E1b, E4] (Mus musculus) PubMed
2295.
Beet curly top virus (BCTV) C4 interacted with two members of the shaggy-related protein kinase family (AtSKeta and AtSKzeta) and a putative leucine-rich repeat receptor-like kinase (LRR-RLK) in a yeast two-hybrid assay.[C4 protein] (Mus musculus) PubMed
2296.
The cloned cDNA is rice black-streaked dwarf virus S7. [S7] (Mus musculus) PubMed
2297.
The cloned S9-1 gene contains 1900 base pairs and encoded a 40 kD protien. [S9-1] (Mus musculus) PubMed
2298.
these results suggest that P9-1 is required for viroplasm formation and that it plays an important role in the early stages of the virus life cycle by forming intracellular viroplasms that serve as the sites of virus replication and assembly.[P9-1] (Mus musculus) PubMed
2299.
chracterization of Pns4; it associated with large cytoplasmic fibrils and formed novel minitubules in infected cultured cells of its leafhopper insect vector; might be involved in the process of assembly of the RDV virion [Pns4] (Mus musculus) PubMed
2300.
Rice dwarf virus exploits tubules composed of a nonstructural viral protein (Pns10) and actin-based filopodia to move into neighboring cells.[Pns10] (Mus musculus) PubMed
2301.
P2 shares structural features with membrane-fusogenic proteins encoded by enveloped animal viruses.(capsid protein P2) (Mus musculus) PubMed
2302.
VP1 protein of IBDV is involved in the efficiency of viral replication and modulates the virulence in vivo. (VP1 protein) (Mus musculus) PubMed
2303.
The IBDV capsid protein contains a functional alpha 4 beta 1 integrin ligand motif, and a single point mutation on this triplet abolishes the cell-binding activity of IBDV. [capsid protein] (Mus musculus) PubMed
2304.
crystallization and preliminary diffraction analysis of various mutant IPNV VP4 constructs [VP4 protease] (Mus musculus) PubMed
2305.
the crystal structure of VP4 protease from infectious pancreatic necrosis virus shows that it has an acyl-enzyme complex for an intermolecular self-cleavage reaction [VP4] (Mus musculus) PubMed
2306.
An IPNV infection of susceptible and permissive CHSE-214 cells could only be neutralized by IgG preparations obtained from rabbits immunized with authentic VP2. (Mus musculus) PubMed
2307.
These results suggest the essential role of Tim40 in sorting/assembly of small Tim proteins [Tim40]. (Mus musculus) PubMed
2308.
Replication protein A stimulated the ATPase activity of the Mcm467 complex. (Mcm467) (Mus musculus) PubMed
2309.
Requirements for the binding of Sindbis virus capsid protein to the cytoplasmic domain of the E2 glycoprotein, (capsid) (Mus musculus) PubMed
2310.
investigated the role of the amino acid residues located at or around position E2 391 and constraints on the length of the endodomain on virus assembly [E2 protein] (Mus musculus) PubMed
2311.
Seven sites of biotin modification were identified in the E2 glycoprotein, while one site of modification in the E1 glycoprotein (K16) was identified, confirming that the E1 protein is almost completely buried in the virus structure.[E2] (Mus musculus) PubMed
2312.
Deletions in the glycoprotein E2 endodomain (delta406-407, delta409-411, and delta414-417) resulted in the failure to assemble virions in mammalian cells [glycoprotein E2] (Mus musculus) PubMed
2313.
SIN nsP2 is critically involved in cytopathic effect development, determined by the integrity of the carboxy-terminal peptide of this protein located outside its helicase and protease domains(nonstructural protein nsP2) (Mus musculus) PubMed
2314.
The defective and lethal mutants give insight into regions of E2 important for protein stability, transport to the cell membrane, E1-E2 contacts, and receptor binding [E2] (Mus musculus) PubMed
2315.
analysis of free cysteinyl residues in the Sindbis virus E1 and E2 glycoproteins [E1, E2] (Mus musculus) PubMed
2316.
Data suggest that Sindbis virus infection leads to the formation of two types of nsP3-containing complexes, one of which is found in association with the plasma membrane and endosome-like vesicles, while the second is coisolated with cell nuclei [nsP3]. (Mus musculus) PubMed
2317.
These results establish the bidirectional transport of nsP2 across the nuclear membrane, suggesting that a critical function of nsP2 during infection involves its shuttling between the cytoplasm and the nucleus.(nsP2) (Mus musculus) PubMed
2318.
results demonstrated a requirement for residues located between amino acids 994-1102 of the RV P200 polyprotein, besides its cleavage site for RV protease trans-activity [P200] (Mus musculus) PubMed
2319.
Two disulfide bonds in the membrane-adjacent part of the E1 ectodomain are sufficient to generate conformations with a high and specific antigenicity[ E1 envelope protein ] (Mus musculus) PubMed
2320.
The effect of nsp3 mutations on replicase polyprotein processing was investigated, and several mutations were found to influence processing of the region downstream of nsp3 by the nsp4 main protease; none of the nsp3 mutations was tolerated.[nsp3] (Mus musculus) PubMed
2321.
E protein - position 123 in the E protein is responsible for determining the growth properties and pathogenicity of JEV (Mus musculus) PubMed
2322.
NMR assignments for domain III of the West Nile virus envelope protein [env] (Mus musculus) PubMed
2323.
there is a critical residue in the C protein of West Nile virus that potentially plays a role in stabilizing the homotypic interaction (Mus musculus) PubMed
2324.
NS1 protein is a viable early diagnostic marker of west nile virus infection. (NS1 protein) (Mus musculus) PubMed
2325.
findings suggest that West Nile virus capsid protein could function as a negative regulator of Hsp70 chaperone activities by binding to the substrate binding domain of Hsp70 [capsid protein] (Mus musculus) PubMed
2326.
identified important enzyme-substrate interactions that define substrate specificity for NS3 protease [NS3 protease] (Mus musculus) PubMed
2327.
extracellular NS1 may function to minimize Soluble and cell-surface-associated nonstructural protein 1 binds to and recruits the complement regulatory protein factor H (Mus musculus) PubMed
2328.
three-dimensional structure (at 3.1 A resolution) of the NS3 helicase domain (residues 186-619; NS3:186-619) from Kunjin virus, an Australian variant of the West Nile virus (Mus musculus) PubMed
2329.
An effective and highly specific interaction of the surface glycoprotein E domain II (DII) of the tick born encephalitis and Dengue viruses with the laminin binding protein (LBP), is shown.[Glycoprotein E] (Mus musculus) PubMed
2330.
tick-borne encephalitis virus -NS5 has high affinity to regulating synaptic membrane exocytosis-2 (RIMS2) and Scribble, whereas DENV-NS5 binds primarily to the tight junction protein zonula occludens-1 (ZO-1) [ns5] (Mus musculus) PubMed
2331.
In the partially surface-exposed BC loop of the envelope protein methionine-304 and valine-324 were identified as being critical for the structure of the loop.[envelope protein] (Mus musculus) PubMed
2332.
The crystal structure of RdRp containing an Asn438 duplication shows that the "N-terminal domain," which occurs only in pestiviruses such as BVDV, interacts with the polymerase component of the same polypeptide chain. (RdRp) (Mus musculus) PubMed
2333.
The viral envelope glycoprotein E(rns) inhibits IFN expression induced by extracellular viral ssRNA and dsRNA. [E(rns)] (Mus musculus) PubMed
2334.
De novo initiation pocket mutations have multiple effects on hepatitis C virus RNA-dependent RNA polymerase activities. (Mus musculus) PubMed
2335.
Mutations in the HCV core gene that would encode a truncated core protein were found in 4 of the 8 hepatocellular carcinoma patients (Mus musculus) PubMed
2336.
Amino acid alterations in HVR1 protein, ISDR and core antigen of hepatitis C virus associated with serum alanine aminotransferase increases. (Mus musculus) PubMed
2337.
HCV core protein (HCV-C)is involved in a tight modulation of HCV translation initiation, depending on its concentration, which suggests an important biological role of this protein in viral gene expression. (HCV core protein; HCV-C) (Mus musculus) PubMed
2338.
HCcAg (core protein) was detected in the nucleii of nonparenchymal liver cells from chronically HCV-infected patients [core protein] (Mus musculus) PubMed
2339.
NS5A-mediated phosphaatidylinositol 3-kinsae activation is a contributory factor in the increasingly common association between HCV infection and the development of hepatocellular carcinoma. (NS5A) (Mus musculus) PubMed
2340.
biological effects of Hepatitis C virus (HCV) core protein on cell cycle could be an additional viral mechanism for both HCV resistance to interferon (IFN) and hepatocarcinoma HCV-related pathogenesis [Hepatitis C virus core protein] (Mus musculus) PubMed
2341.
C-terminal 18 amino acids of HCV core were crucial for core secretion. HCV may utilize a unique core release mechanism to escape immune surveillance, thereby potentially representing feature of HCV morphogenesis. (HCV core protein) (Mus musculus) PubMed
2342.
A hepatitis C virus protein; study of its conformation and zinc binding domain.(NSrA protein) (Mus musculus) PubMed
2343.
results suggest that interaction of core protein with mitochondria and subsequent oxidation of the glutathione pool and complex I inhibition may be an important cause of the oxidative stress seen in chronic hepatitis C [core protein] (Mus musculus) PubMed
2344.
These biochemical and functional analyses identified a number of residues in the HCV RNA-dependent RNA polymerase(RdRp) that are important for HCV RNA synthesis.[RdRp] (Mus musculus) PubMed
2345.
identification of interaction between HBcAg and the novel protein C12 (Mus musculus) PubMed
2346.
the target of NS3/4A is the mitochondrial antiviral signaling protein, MAVS, that activates NF-kappaB and IFN regulatory factor 3 to induce type-I interferons [NS3 and NS4A] (Mus musculus) PubMed
2347.
specific amino acid substitutions in hepatitis C virus NS3 impair p53 interaction and anti-apoptotic activity of NS3 (Mus musculus) PubMed
2348.
The cleaveage of nonstructural protein 5A(NS5A) of the hepacivirus at two sites, and its targeting to different caspases are reported.[NS5A] (Mus musculus) PubMed
2349.
data suggested that the introduction of HCV core protein results in an increase in expression of IL-6, gp130, leptin receptor, and Stat3 in human hepatocytes [core protein] (Mus musculus) PubMed
2350.
Results indicate that hepatitis C virus NS5A protein may be directly involved in the induction of chromosome instability via mitotic cell cycle dysregulation [NS5A]. (Mus musculus) PubMed
2351.
identification of several clusters of genes that are differentially expressed in human B lymphocytes expressing HCV core, suggesting a potential impairment of antigen processing and presentation (Mus musculus) PubMed
2352.
crystal structure of the catalytic domain of the NS2-3 protease at 2.3 A resolution [NS2-3 protease] (Mus musculus) PubMed
2353.
Core protein, detectable in the plasma of HCV infected patients, triggers plasmacytoid dendritic cell (PDC) defects that are likely to contribute to HCV viral escape from immune responses. (N protein; nucleocapsid) (Mus musculus) PubMed
2354.
Transient or stable NS5A expression inhibits STAT1 phosphorylation in a dose-dependent manner in hepatocyte-derived cell lines. The NS5A may interact with STAT1, specifically, the N-terminal 488 amino acids of STAT1. STAT1 protein, hepatitis C (Mus musculus) PubMed
2355.
interferon-inducible gene 27 (IFI27) was highly expressed in NS3 and NS5A-infected hepatocytes and HCV-related CLD or HCC (NS3, NS5) (Mus musculus) PubMed
2356.
sequence barriers in RNA modulate NS3 activity, whichdepends on barriers ahead of the opening fork of the RNA [NS3 helicase] (Mus musculus) PubMed
2357.
Variants of full-length hepacvirus NS3 constitute effective models for resistance profiling of NS3 protease inhibitors. (Mus musculus) PubMed
2358.
Ribovarin induces mutations in HVC NS5A sequence, modifying infectivity and interferon sensitivity. (Mus musculus) PubMed
2359.
These data suggest that HCV core protein may contribute to hepatocellular injury by increasing both steady-state levels of prooxidants and the susceptibility of hepatocytes to damage by impairing their response to other sources of oxidative stress.[HO-1] (Mus musculus) PubMed
2360.
Synthetic siRNA against NS5BHCV inhibited HCV replication and viral proteins levels and thereby becomes a powerful strategy to combat hepatitis C virus [NS5BHCV]. (Mus musculus) PubMed
2361.
Hepatitis C virus non-structural 5A protein (NS5A) has central role in viral life cycle and in the progression of liver disease. (Mus musculus) PubMed
2362.
Nonstructural protein 5A proteinof hepatitis C virus plays an important role in the regulation of viral replication, interferon resistance, and apoptosis. [Nonstructural protein 5A] (Mus musculus) PubMed
2363.
Engagement of gC1qR on DCs by HCV core limits the induction of Th1 responses and may contribute to viral persistence.[Core protein] (Mus musculus) PubMed
2364.
Response of HCV-1b infected patients towards interferon therapy is influenced by the mutations within the interferon sensitivity determining region of NS5A gene. (Mus musculus) PubMed
2365.
Designed protease inhibitors based on structural features of hepatitis C virus NS3 protease. (Mus musculus) PubMed
2366.
NS5ATP9 is a non-structural protein 5A (NS5A) up-regulation gene which may play a role in the pathogenesis of HCV-associated hepatocellular carcinoma. (Mus musculus) PubMed
2367.
Aim of the studies included detection and subcellular localization of three HCV proteins (NS3, NS5A and C) in liver biopsies from adults (n=19) with chronic, long lasting hepatitis C as related to hepatocyte proliferative activity.[NS3, NS5A, C] (Mus musculus) PubMed
2368.
support interactions that include a 1:1 complex formed between NS3 and NS5B[NS3 helicase and NS5B] (Mus musculus) PubMed
2369.
data suggest an important role for mitochondria in the modulation HCV NS4A-induced inhibition of HCV core-mediated cell growth [NS4A protein] (Mus musculus) PubMed
2370.
Mutations in NS5A causing an assembly defect in hepatitis C virus can be rescued by trans-complementation. (Mus musculus) PubMed
2371.
Collectively, these results provide the first evidence for a genetic interaction between NS4B and NS3 important for productive HCV RNA replication.[NS3, NS4B] (Mus musculus) PubMed
2372.
large kinetic step size of NS3 unwinding reflects a delayed, periodic release of the separated RNA product strand from a secondary binding site that is located in the NTPase domain (Domain II) of NS3[ NS3 helicase] (Mus musculus) PubMed
2373.
The structure of the inhibitor/NS3p complex is very similar to that of the NS3p-NS4A complex, showing that binding of the NS4A cofactor is not the only event leading to a stable active-site conformation.[NS3, NS4A] (Mus musculus) PubMed
2374.
The protease domain with the NS4A peptide, in a covalent or noncovalent complex, is a good model for the protease activity of native full-length nonstructural proteins NS3-NS4A. (Mus musculus) PubMed
2375.
In conclusion, the core gene contains an internal signal that stimulates the initiation of protein synthesis at or near codon 91, leading to the production of p8.[p8] (Mus musculus) PubMed
2376.
monomer-monomer interface of NS5A(33-202) features an extensive buried surface area involving the most-highly conserved face of each monomer[ NS5A ] (Mus musculus) PubMed
2377.
impairment of Hsp60 function through binding of HCV core protein contributes to HCV viral pathogenesis by ROS generation and amplification of the apoptotic effect of TNF-alpha.(HVC core protein) (Mus musculus) PubMed
2378.
The authors propose that although domain III of NS5A is dispensable for RNA replication, it nevertheless influences this process. (Mus musculus) PubMed
2379.
NS5A and core proteins induce oxidative stress-mediated Ca(2+) homeostasis alterations in human hepatocyte-derived cells, which might underlie the effects of both proteins in the pathogenesis of liver disorders associated to HCV infection [NS5A]. (Mus musculus) PubMed
2380.
Formation of N-terminally truncated NS5A fragments could represent a mechanism to regulate HCV replication by withdrawal of essential factors from the replicon complex [NS5A]. (Mus musculus) PubMed
2381.
HCV NS3protein inhibits the interferon transmission system, and suppresses activation of the interferon-stimulated response element. (Mus musculus) PubMed
2382.
The three-dimensional structure of the HCV polymerase from genotype 2b was determined to 1.9-A resolution and compared with the genotype 1b enzyme.[NS5B] (Mus musculus) PubMed
2383.
Luciferase assay showed that hepatitis C virus NS4B also activates the multifunctional transcription factor, NF-kappaB, in a dose-dependent manner through Ca(2+) signaling and reactive oxygen species.[NS4B] (Mus musculus) PubMed
2384.
Nonstructural HCV viral protein NS5A is sufficient to activate a calpain cysteine protease, leading to degradation of Bid [NS5a]. (Mus musculus) PubMed
2385.
hepatitis c virus RNA-dependent RNA polymerase -- structural and functional analysis in HCV strain JFH1 (Mus musculus) PubMed
2386.
C-terminal leucine is locked in the active site, and mutation or deletion of this residue could therefore alter the conformation of NS2 and disrupt potential protein-protein interactions important for infectious particle production. (NS2 PROTEIN) (Mus musculus) PubMed
2387.
analysis of nonstructural proteins 8 and 9 of human coronavirus 229E [nsp8, nsp9] (Mus musculus) PubMed
2388.
analysis of SARS coronavirus main proteinase (Mpro) [3C or Mpro] (Mus musculus) PubMed
2389.
The highly conserved amino acid sequence of the ORF4 protein among clinical isolates suggests that the protein plays an important role in vivo. [ORF4] (Mus musculus) PubMed
2390.
Within the tightly controlled interplay of the two protease activities, PL2pro plays a universal and essential proteolytic role that appears to be assisted by the PL1pro paralog at specific sites.[PL1pro, PL2pro] (Mus musculus) PubMed
2391.
Both forms of the Nsp9 dimer are biologically relevant; the occurrence of the disulfide-bonded form may be correlated with oxidative stress induced in the host cell by the viral infection.[Nsp9] (Mus musculus) PubMed
nsp2 proteins of mouse hepatitis virus and SARS coronavirus are not critical for viral replication [nsp2] (Mus musculus) PubMed
2394.
TGEV spiker protein belongs to the class I fusion protein, characterized by the existence of two heptad-repeat (HR) regions, HR1 and HR2 [spiker] (Mus musculus) PubMed
2395.
These results indicate that SeV V protein counteracts IRF-3-mediated innate antiviral immunity for efficient virus replication and pathogenesis in mice [V protein] (Mus musculus) PubMed
2396.
From our data, we conclude that de novo synthesis of SeV N and P proteins is a key step for viral gene expression that facilitates the transition from preliminary to normal primary transcriptional activity. [N protein] (Mus musculus) PubMed
2397.
PD protein localized in nuclear and cytoplasmic compartments of HPIV 3 infected cells.[PD protein] (Mus musculus) PubMed
2398.
when P protein was co-expressed with the L protein, the former bound to a domain spanning the N-terminal 1060 amino acids of the latter preventing L-L self-association and resulting in functionally active RNA-dependent RNA polymerase.[L] (Mus musculus) PubMed
2399.
genetic analysis revealed that amino acids 238-266 of V protein were necessary for efficient RNA binding and overlapped with residues (238-278) required for maximal repression induced by the C-terminal domain.[V protein] (Mus musculus) PubMed
2400.
V protein was found to repress reporter activity. Two regions of the polypeptide contributed to this repressive effect including the carboxy-terminus and a region conserved in morbillivirus V proteins located between amino acids 110-131 [V] (Mus musculus) PubMed
2401.
results show that the codon for amino acid 522 of the MV N protein plays an important role in both in vitro and in vivo viral fitness (Mus musculus) PubMed
2402.
These results indicate that the putative NES (nuclear export sequence) is functional and that C protein has the ability to shuttle between the nucleus and the cytoplasm. [C protein] (Mus musculus) PubMed
2403.
Using the two-hybrid system and co-affinity purification experiments, we identified STAT1 and Jak1 as interactors of MV-V and demonstrate that MV-V can block the direct phosphorylation of STAT1 by Jak1. [V protein] (Mus musculus) PubMed
2404.
We concluded that one mutation, of the histidine at position 1042 of p150, was essential for the ts phenotype of the KRT strain. [P150] (Mus musculus) PubMed
2405.
The interaction of measles virus V protein with STAT2 is carried by the cysteine-constrained peptide of 49 amino acids localized in the VCT region, and is essential to the inhibition of IFN-alpha/beta signaling.[V] (Mus musculus) PubMed
2406.
experiments demonstrated that mannose-binding lectin (MBL) binds to envelope glycoprotein resulting in important biological effects and suggest that MBL can interact with filoviruses during infection in humans [Env protein] (Mus musculus) PubMed
2407.
crystal structure of proteinase-K-resistant domain within the P phosphoprotein [P phosphoprotein] (Mus musculus) PubMed
2408.
self-association domain of phosphoprotein of Indiana serotype plays a critical role in vesicular stomatitis virus transcription. (Mus musculus) PubMed
2409.
a specific sequence in VSV G protein, comprising the residues 145 to 164, directly involved in membrane interaction and fusion.[G glycoprotein] (Mus musculus) PubMed
2410.
Taking these results together, we conclude that the N-terminal 11 to 30 aa are required for N(0)-P complex formation but the N-terminal 210 aa are required for genome RNA encapsidation. [N protein, P protien] (Mus musculus) PubMed
2411.
p37-1 is a substrate for p40 production catalyzed by heparin-sensitive PK (protein kinase) in animal cells [P protein] (Mus musculus) PubMed
2412.
cloned and sequenced the nucleoprotein gene[Rabies virus 5aG strain, Nucleoprotein ] (Mus musculus) PubMed
2413.
the localization of the nuclear localization signal and the CRM1-dependent nuclear export signal determines the cellular distribution of the P gene products [P protein] (Mus musculus) PubMed
2414.
phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3 [P protein] (Mus musculus) PubMed
2415.
Rabies virus P protein does not induce STAT1 degradation and does not interfere with STAT1 phosphorylation. (Mus musculus) PubMed
2416.
N-terminal sequencing and mass spectrometry analysis identified a phosphhoprotein peptide containing residues 4-40 that binds to nucleoprotein and keeps it soluble [Phosphoprotein P] (Mus musculus) PubMed
2417.
phosphoprotein P inhibits interferon signaling via activation- dependent binding to STAT1 and STAT2 [phosphoprotein P] (Mus musculus) PubMed
2418.
products of the rabies virus P gene are able to counteract IFN signaling by creating both cytoplasmic and nuclear blocks for STAT1.[P protein] (Mus musculus) PubMed
2419.
an amino acid at position 95 of the matrix protein is a cytopathic determinant of the rabies virus and the cytopathic effect is, at least partly, due to apoptosis (Mus musculus) PubMed
2420.
results show NGF but not NT-3 caused increase of P protein & accumulation in neuronal bodies, revealing change in transport to neuritic processes; work shows part of cellular mechanisms regulating P protein expression during the viral cycle [P protein] (Mus musculus) PubMed
2421.
results suggest a conserved organization of P proteins in the Rhabdoviridae family in concatenated functional domains resembling that of the P proteins in the Paramyxoviridae family[P protein] (Mus musculus) PubMed
2422.
sequence of the 1918 influenza virus polymerase genes, PB1, PB2, and PA [PB1] (Mus musculus) PubMed
2423.
We demonstrated that the direct binding of the NS1A protein to the N-terminal 230 amino acid region of PKR inhibits PKR activation by PACT and dsRNA [Ns1A, A/Udorn/72] (Mus musculus) PubMed
2424.
hemagglutinin structure at 2.9 angstrom resolution; receptor specificity of mutations [hemagglutinin, H5N1 influenza virus A/Vietnam/1203/2004] (Mus musculus) PubMed
2425.
results show that NS1 protein from human H5N1 influenza isolate A/HK/156/97 reduces both systemic and pulmonary pro-inflammatory cytokines in an in vivo mouse model and protects against bone marrow lymphocyte depletion [NS1] (Mus musculus) PubMed
2426.
Data suggest that the primary role of double-stranded RNA binding by the NS1A protein in virus-infected cells is to sequester dsRNA away from RNAse L. (Mus musculus) PubMed
2427.
Data show that protonation of the third of four imidazoles coincides with acid activation of M2 and that, at physiological pH, the channel is closed by two imidazole-imidazolium dimers, each sharing a low-barrier hydrogen bond. (Mus musculus) PubMed
2428.
N-terminal region of PA is involved in multiple functions of the polymerase, including protein stability, endonuclease activity, cap binding, and promoter binding. (Mus musculus) PubMed
2429.
Knocking out the PB1-F2 protein had no effect on viral replication in tissue culture but diminished virus pathogenicity and mortality in mice. (Mus musculus) PubMed
2430.
the M2 protein cytoplasmic tail is a crucial mediator of infectious virus production binding through its cytoplasmic tail to M1 protein. (M2 protein) (M1 protein) (Mus musculus) PubMed
2431.
Results report that influenza A virus NS1 binds directly to p85beta, a regulatory subunit of phosphatidylinositol-3-kinase (PI3K), but not to the related p85alpha subunit [NS1]. (Mus musculus) PubMed
2432.
The bipartite nuclear localization signal, but not the unconventional nuclear localization signal, of NP is essential for influenza A virus replication (NP). (Mus musculus) PubMed
2433.
Mutations at positions 182 and 192 independently convert the HAs of H5N1 viruses known to recognize the avian receptor to ones that recognize the human receptor [HA] (Mus musculus) PubMed
NS1 not only blocks but also activates signaling pathways to ensure efficient virus replication (Mus musculus) PubMed
2437.
The data suggest that PB2 might play a pivotal role in molecular interactions involving both the viral nucleoprotein and cellular proteins. [PB2 protein] (Mus musculus) PubMed
2438.
two amino acid mutations in the hemagglutinin that cause a switch in receptor binding preference resulted in a virus incapable of respiratory droplet transmission between ferrets [hemagglutinin, H1N1 virus] (Mus musculus) PubMed
2439.
An independently folded C-terminal domain from PB2 was identified and its solution structure was determined by NMR. Both the domain and the full-length PB2 subunit are efficiently imported into the nucleus. (Mus musculus) PubMed
2440.
the direct binding of PKR to the NS1 protein in vitro that results in inhibition of PKR activation requires the NS1 123-127 amino acid sequence [NS1] (Mus musculus) PubMed
2441.
Here we show that influenza virus PA causes the specific degradation of the hypophosphorylated form of the largest subunit of RNAP II without affecting the accumulation of its hyperphosphorylated forms.[PA] (Mus musculus) PubMed
2442.
It is likely that the evolutionarily well-conserved nucleolar targeting function of nonstructural protein 1 (NS1A protein) plays a role in the pathogenesis of influenza A virus. [NS1A] (Mus musculus) PubMed
2443.
The NS1 protein down-regulates the splicing and blocks the nuclear export of its own viral mRNA (NS1). (Mus musculus) PubMed
2444.
We molecularly characterized the hemagglutinin (HA) and neuraminidase (NA) genes of the A/China/GD01/06 (GD01) strain causing the human H5N1 infection. [HA] (Mus musculus) PubMed
2445.
results demonstrate that both NLS1 and NLS2 on NP can mediate the nuclear uptake of influenza A vRNPs [NP] (Mus musculus) PubMed
2446.
The extracellular and cytoplasmic domains of M2 protein were not essential for ion channel activity of M2 protein. [M2 protein] (Mus musculus) PubMed
2447.
We conclude that the L163-I178 region of PA is directly or indirectly involved in cRNA promoter binding and suggest a novel function for RNA polymerase PA subunit in modulating promoter binding. [PA] (Mus musculus) PubMed
2448.
It was found that the D92E mutation could result in weakened interactions of the carboxylate side chain with other phosphorylated residues, thereby activating phosphorylation of NS1 [NS1] (Mus musculus) PubMed
2449.
the deletion of amino acids 191 to 195 of the NS1 protein is critical for the attenuation of the SW/FJ/03 virus in chickens and that this deletion affects the ability of the virus to antagonize IFN induction in host cells. (Mus musculus) PubMed
2450.
The results suggest that G8 as well as E11 play an important functional and structural role in membrane fusion and that the polarity of E11 is crucial for fusion activity.[A/chicken/Fujian/1042/2005 (H5N1) strain] (Mus musculus) PubMed
2451.
NS1 protein is critical for the pathogenicity of H5N1 influenza viruses in mammalian hosts and that the amino acid S42 of NS1 plays a key role in undermining the antiviral immune response of the host cell.[NS1 in A/Duck/Guangxi/27/03 strain] (Mus musculus) PubMed
2452.
the side-chain conformation and position of Trp41 differs significantly in the two pH-dependent states of the proton channel of M2TMD.(M2TMD) (Mus musculus) PubMed
2453.
study identified a region of conserved basic amino acids near the C-terminus of PB1 involved in regulating viral transcription. [PB1] (Mus musculus) PubMed
2454.
the structure of the tetrameric M2 channel in complex with rimantadine, determined by NMR [M2] (Mus musculus) PubMed
2455.
crystal structure of the transmembrane-spanning region of the homotetrameric M2 protein in the presence and absence of the channel-blocking drug amantadine [M2] (Mus musculus) PubMed
2456.
in vivo formation and in vitro renaturation of the N5D3 epitope depend on inter-subunit interactions of monomeric NPs and NP-NP interactions influence the antigenic structure of the influenza virus NP polymers.[NP] (Mus musculus) PubMed
2457.
Our data indicate that NA alone among viral proteins limits influenza A virus superinfection.[NA] (Mus musculus) PubMed
2458.
NS1 sequences from the 1918 H1N1 and H5N1 highly pathogenic avian influenza viruses demonstrated increased virulence in infected mice compared with wt A/WSN/33 virus [NS1] (Mus musculus) PubMed
2459.
the enzymatic properties and crystal structures of neuraminidase mutants from H5N1-infected patients that explain the molecular basis of resistance [neuraminidase] (Mus musculus) PubMed
2460.
We report a crystal structure for the NS1 effector domain of avian influenza virus A/Duck/Albany/76,and show that tryptophan-187 (a residue located at the helix-helix interface) is essential for dimerization of this effector domain. [NS1] (Mus musculus) PubMed
2461.
Phylogenic analysis of the matrix (M) genes of 67 strains revealed that A/duck/Hokkaido/W95/2006 (H10N8) was a reassortant virus. (Mus musculus) PubMed
2462.
Coarse-grained molecular dynamics (CG-MD) simulations have been used to explore partitioning into a membrane of M2 transmembrane helices during bilayer self-assembly from lipids.[M2 protein] (Mus musculus) PubMed
2463.
X-ray structure of the full-length NS1 from an H5N1 strain (A/Vietnam/1203/2004) that was associated with 60% of human deaths in an outbreak in Vietnam [NS1] (Mus musculus) PubMed
2464.
An in-depth analysis of M2 channel was performed for its functional studies, particularly for the mutations D44N, D44A and N44D on position 44, and the mutations on positions 27-38. (Mus musculus) PubMed
2465.
The authors conclude that M1 probably interacts with membranes via multiple binding sites.[M1 in strain A/FPV/Rostock/34] (Mus musculus) PubMed
2466.
The data suggest that CDK/ERK-mediated phosphorylation of NS1 at threonine-215 is important for efficient virus replication. (Mus musculus) PubMed
2467.
These results indicate that the PB2 protein restricts the growth of Ck/Yamaguchi/04 (H5N1) in pigs.[PB2 in strain Ck/Yamaguchi/04] (Mus musculus) PubMed
2468.
Phylogenetic analysis shows that two distinct gene pools, corresponding to both NS allele A and B, were present in the mallard populations in Northern Europe. [NS] (Mus musculus) PubMed
2469.
The different protonation states of the His-37 residues of the M2 bundle in a bilayer was explored using molecular dynamics (MD) simulations.[M2 protein] (Mus musculus) PubMed
2470.
The authors demonstrated an interaction between PA and PB2 that has not been reported previously.[PA & PB2 in strain H1N1 A/WSN/33] (Mus musculus) PubMed
2471.
The data show that residues comprising the fusion peptide pocket are important in triggering pH-dependent activation of the H5 HA protein.[HA in strain A/chicken/Vietnam/C58/04 (H5N1)] (Mus musculus) PubMed
2472.
biochemical and structural studies showing that the amino-terminal 209 residues of the PA subunit contain the endonuclease active site; this domain has intrinsic RNA and DNA endonuclease activity that is strongly activated by manganese ions [PA] (Mus musculus) PubMed
2473.
The 1918 PB2 protein was found to be both necessary and sufficient for airborne transmission of a virus expressing the 1918 HA and neuraminidase [HA & PB2] (Mus musculus) PubMed
2474.
The data suggest that protein kinase C contributes to the phosphorylation of influenza PB1 and NS1 proteins which appears to be functionally relevant for both viral RNA polymerase activity and efficient viral replication.[PB1 & NS1 in A/WSN/33 virus] (Mus musculus) PubMed
2475.
A role for the NS2/NEP protein in the regulation of influenza virus transcription and replication that is independent of its viral RNP export function is proposed.[NS2/NEP] (Mus musculus) PubMed
2476.
A wide range of complexes of influenza A neuraminidases with inhibitor molecules (sialic acid derivatives & others) have been analyzed; strongest interactions of the residues are with the acidic group at the C2 position of the inhibitor [neuraminidase] (Mus musculus) PubMed
2477.
NS1 truncated mutant demonstrated limited viral replication and enhanced type I IFN induction. (Mus musculus) PubMed
2478.
High degree of conservation in the NS1 and NS2 were found among influenza A virus subtypes. [NS1, NS2] (Mus musculus) PubMed
2479.
The results showed that a siRNA targeting influenza M2 gene (siM2) potently inhibited viral replication.[M2 protein] (Mus musculus) PubMed
2480.
The expression of N40, PB1-F2, and PB1 are interdependent, and certain mutations ablate PB1-F2 production affected N40 accumulation. [N40] (Mus musculus) PubMed
2481.
NF90 inhibits influenza virus replication during the early phase of infection through direct interaction with viral NP. [NP] (Mus musculus) PubMed
2482.
ESI-MS analysis and cellular expression of PB1-F2 mutants identified the positions Ser-35 as the major and the Thr-27 as an alternative PKC phosphorylation site.[PB1-F2] (Mus musculus) PubMed
2483.
Functional data on M2 proton channel activity and high-resolution structural information available describing the transmembrane domain are summarized. (Mus musculus) PubMed
2484.
Molecular dynamics (MD) simulations of the M2 transmembrane domain (TMD) in the absence and presence of the antiviral drug amantadine, is reported.[M2 protein] (Mus musculus) PubMed
2485.
Analysis of 391 influenza A (H1N1) viruses identified a previously undescribed Gln136Lys (Q136K) neuraminidase mutation conferring zanamivir resistance (confirmed using reverse genetics). [NA] (Mus musculus) PubMed
2486.
M1 blocked the interaction between C1qA and heat-aggregated IgG in vitro and inhibited haemolysis.[M1] (Mus musculus) PubMed
2487.
The nucleoprotein (NP) displayed very slow mobility that significantly increased on formation of transcriptionally active viral ribonucleoproteins. (Mus musculus) PubMed
2488.
These results show that a highly pathogenic avian influenza virus can be attenuated by modulating the caspase cleavage sites of NP and M2.[NP and M2] (Mus musculus) PubMed
2489.
The HA1 protein of swine H1N1/N2 viruses and the new A/H1N1 of viruses differed in conserved characteristics that reflect a distinct propensity of these viruses to undergo a specific interaction with swine or human host proteins or receptors. (Mus musculus) PubMed
2490.
This is the first study showing that the isoleucine residue at position 97 in PA plays a key role in enhanced virulence in mice and is implicated in the adaptation of avian influenza viruses to mammalian hosts. (Mus musculus) PubMed
2491.
Ataxin 10 and eukaryotic initiation factors interacts with M2 protein of influenza A virus. (Mus musculus) PubMed
2492.
Loss of a single N-linked glycan from the hemagglutinin of influenza virus (H3N2 strain A/Beijing/353/89) is associated with resistance to collectins and increased virulence in mice. (Mus musculus) PubMed
2493.
RVFV NSm protein is the first identified Phlebovirus protein that has an antiapoptotic function. [NSm protein] (Mus musculus) PubMed
2494.
Molecular-mass measurements suggest a G(N)-G(C) heterodimer as the most likely candidate for the capsomers.[G protein] (Mus musculus) PubMed
2495.
NSs proteins of the related but less virulent sandfly fever Sicilian virus and La Crosse virus, in contrast, had no such anti-double-stranded RNA-dependent protein kinase(PKR) activity despite being efficient suppressors of IFN induction[ PKR] (Mus musculus) PubMed
2496.
Hydrophobic region of glycoprotein C(GP-C) signal peptide is sufficient for the membrane insertion of GP-C, while both hydrophobic regions are required for the processing and cell surface expression of the GPs.(Glycoprotein C) (Mus musculus) PubMed
2497.
The results showed that of the substituted residues, only H1189 and D1329 appeared to be critically involved in binding Z.[Z protein] (Mus musculus) PubMed
2498.
Interaction between Z and N is required for assembly of the nucleocapsids and the glycoproteins into infectious arenavirus budding particles. [Z protein] (Mus musculus) PubMed
2499.
These results indicate that tacaribe virus Z protein utilizes a budding mechanism distinct from that reported for other arenaviruses. (Mus musculus) PubMed
2500.
results suggest that the mutated residues of may not be responsible for the higher pH optimum of HFV protease, but they may contribute to the lower dimer stability as compared with that of HIV-1 protease [protease] (Mus musculus) PubMed
2501.
Biologic activity of equine infectious anemia virus (EIAV) surface (SU) glycoprotein was assayed in a mouse model. [SU] (Mus musculus) PubMed
2502.
These results demonstrate that S2 gene expression is essential for disease expression of EIAV. (Mus musculus) PubMed
2503.
3D structure of 37-aa peptide from lentiviral EIAV nucleocapsid, complexed with zinc, contains 2 zinc binding domains held together by 5-residue basic linker Arg(38)-Ala-Pro-Lys-Val(42) that allows for spatial proximity between 2 finger domains[NCp11] (Mus musculus) PubMed
2504.
Epitope analysis of the p26 EIAV core protein. [p26] (Mus musculus) PubMed
2505.
Cytoplasmic tail truncation of EIAV env protein can cause an increase in the ability to induce cell death by mitochondria mediated necrosis within the env expressing cells. [Env] (Mus musculus) PubMed
2506.
Mutations in the S2 of the EIAV vaccine strains did not significantly alter the viral replication in vitro. [S2] (Mus musculus) PubMed
2507.
The design of several peptides derived from the FIV envelope protein gp36, their homology to HIV gp41, and the residues of the C-terminal region that are critical for interaction with the N-terminal region are reported.[gp36] (Mus musculus) PubMed
2508.
Severevirus attenuation for both replication and pathogenicity exhibited by a vif-deleted FIV mutant is similar for both neonatal and adult hosts. [fiv protein] (Mus musculus) PubMed
2509.
The analyses revealed alterations in genes critical for RNA post-transcriptional modifications and protein ubiquitination as the two most significant functional outcomes of OrfA expression. [OrfA] (Mus musculus) PubMed
2510.
P59 insertion between the lipid headgroups leads to significant liposome destabilization[glycoprotein gp36 ] (Mus musculus) PubMed
2511.
FIV is displaying relative little sequence variation during infection of its host, both in the env and the orfA gene [OrfA] (Mus musculus) PubMed
2512.
HIV-1-gp120 may predispose resting CD4(+)T cell to bystander CD95-mediated apoptosis and support the key role of ezrin/CD95 linkage in regulating susceptibility to CD95-mediated apoptosis [HIV-1 gp120]. (Mus musculus) PubMed
2513.
the role of the HIV-1 nucleocapsid protein p7 (NCp7) in the fate of the HIV-1 full length RNA from genomic RNA in a dimeric form to the proviral DNA.[NCP7] (Mus musculus) PubMed
2514.
Transcription, splicing, steady state RNA levels, and pr55Gag processing were not affected in hnRNP A2 HIV-1. (hnRNP A2) (Mus musculus) PubMed
2515.
Evolution of the HIV-1 V3 loop was monitored in 15 HIV subjects; recombination was detected in many of the sequences. (Glycoprotein 120 in HIV-1) (Mus musculus) PubMed
2516.
These studies suggest that gp120 may induce neuronal apoptosis in the CNS of HIV-associated dementia patients through the CXCR4-NADPH oxidase-superoxide-NSMase-ceramide pathway. [gp120] (Mus musculus) PubMed
2517.
gp120 has the capacity to dysregulate the vast CD4+ T cell population that expresses CXCR4 and may exploit its chemotactic properties to retain potential target cells and locally perturb their cytoskeleton, facilitating viral transmission. (gp120 env) (Mus musculus) PubMed
2518.
The ability of CD4 antigen-primed gp120 to block stromal cell-derived factor 1 (SDF-1) signaling in mouse neural progenitors may contribute to the neuropathological effects of HIV-1. (envelope surface glycoprotein gp120) (Mus musculus) PubMed
2519.
Efavirenz binds to HIV-1 reverse transcriptase predominantly through strong electrostatic interaction with the Lys101 residue. (reverse transcriptase) (Mus musculus) PubMed
2520.
Two C3d elements are able to elicit gp120 binding antibodies more efficiently than gp120 lacking C3d moieties. (gp120) (Mus musculus) PubMed
2521.
Toward the end of the asymptomatic period there was a change in the V3-loop structure or in the environment surrounding the V3 loop, possibly because of its proximity to the gp120 core. (gp120) (Mus musculus) PubMed
2522.
Two soluble trimeric recombinant gp41 proteinscan interfere with multiple steps of the HIV entry process. (gp41 protein) (Mus musculus) PubMed
2523.
gp120 may elicit polyclonal IgG and IgA responses by linking the innate and adaptive immune systems through the B cell-activating factor of the TNF family [gp120] (Mus musculus) PubMed
2524.
p24 may be an accurate low-cost alternative to monitor antiviral agents in pediatric HIV-1 infections (HIV-1 p24 antigen) (Mus musculus) PubMed
2525.
Integrase is an efficient mediator of DNA nuclear import in vitro and implies the potential for IN to fulfil such a role in vivo [IN] (Mus musculus) PubMed
2526.
The results establish a molecular mechanism for LEDGF/p75-mediated tethering of HIV-1 integrase to chromatin. [HIV-1 Integrase] (Mus musculus) PubMed
2527.
Frequency of K65R in combination with thymidine-analogue mutations at the genomic level of HIV-1[HIV-1 reverse-transcriptase] (Mus musculus) PubMed
2528.
correlate with deletion studies mapping the domain and subdomain boundaries of reverse transcriptase and integrase [integrase] (Mus musculus) PubMed
2529.
hydration sites study and a detailed analysis of the solvation of the nucleotide binding site are also presented[ reverse transcriptase] (Mus musculus) PubMed
2530.
Two regions within the enzyme involved in the interaction with LEDGF/p75, were identified and characterised.[HIV-1 integrase] (Mus musculus) PubMed
2531.
The study focused on the recognition step and examined possible peptide-peptide interactions between various principle neutralizing determinant (PND)-derived peptides from the V3-loop and the N-terminal (Nt) domain of CCR5. (Mus musculus) PubMed
2532.
could be applied for the characterization of gp41 conformers for use in immunological screening of antigens[gp41] (Mus musculus) PubMed
2533.
Stimulation of two receptors together, using gp120, a component of HIV enhanced cell adhesion greater than stimulation of CD4 or CXCR4 individually. (gp120) (Mus musculus) PubMed
2534.
These data reveal that HIV-1 can escape from an inhibitor of viral entry by acquiring mutations that cause the cytoplasmic tail of gp41 to be cleaved by the viral protease. (Mus musculus) PubMed
2535.
When bound to lipid bilayers at low concentration, the HIV fusion domain is also largely alpha-helical, as determined by CD and FTIR spectroscopy. [gp41 HIV fusion protein] (Mus musculus) PubMed
Studies with P-TEFb inhibitors demonstrate a loss of the large form of P-TEFb within the cell and a concomitant reduction in HIV-1 infectivity/ {P-TEFb] (Mus musculus) PubMed
2538.
von Hippel-Lindau binding protein and cullin2/von Hippel-Lindau are required for proper HIV-1 expression at a step between integrase-dependent proviral integration into the host genome and transcription of viral genes[integrase] (Mus musculus) PubMed
2539.
The first part of the NHR domain could be involved in the first steps of the destabilization of the HIV-1 gp41 six-helix bundle after its interaction with negatively charged phospholipid headgroups.[gp41] (Mus musculus) PubMed
2540.
Diketoacid (DKA) compounds have been shown to inhibit HIV-1 integrase by a mechanism that involves sequestration of the active site metals. (Mus musculus) PubMed
2541.
Double-stranded RNA-activated protein kinase (PKR) is involved in HIV/glycoprotein 120-associated neurodegeneration. [gp120; glycoprotein 120] (Mus musculus) PubMed
2542.
Chronic alcohol drinking augmented the adverse effects of HIV-1 gp120 possibly by suppressing its degradation in hepatocytes. (Mus musculus) PubMed
2543.
[p16 pol gene product]report two high-resolution crystal structures of wild-type protease (Mus musculus) PubMed
2544.
CBD1 but not CBD2 binds cells and forms large aggregates at the plasma membrane by colocalizing with cytofacial caveolin-1.[gp41] (Mus musculus) PubMed
2545.
The sensitivities of the R5X4 strain to coreceptor inhibitors were altered by a single amino acid substitution in the V3 region of gp120.[gp120] (Mus musculus) PubMed
2546.
N-acetyl-LWYIK-amide (LWYIK) represents the naturally-occurring CRAC motif segment in the pretransmembrane region of the gp41 protein of HIV-1. (Mus musculus) PubMed
2547.
The interaction between residues 322 and 440 of gp120 may serve as part of the molecular switch for HIV-1 phenotype conversion. (Mus musculus) PubMed
2548.
HIV-1 and gp120 can induce breast cancer cell apoptosis through gp120-CXCR4 interaction without a CD4-induced conformational change of gp120 [gp120] (Mus musculus) PubMed
2549.
p17 induces immature circulating plasmacytoid dendritic cells to home in lymph nodes devoid of their ability to serve as a link between innate and adaptative immune systems.[p17] (Mus musculus) PubMed
2550.
the loss of the N448 glycan induces structural changes in the C4 region of gp120 that make this specific region more resistant to proteolytic processing, thereby restricting the generation of CD4 T cell epitopes from this region [gp120] (Mus musculus) PubMed
2551.
detailed understanding of the molecular interactions mediating the immunosuppressive activity of the FP(5-13) motif should facilitate evaluating its contribution to HIV pathology and its exploitation as an immunotherapeutic tool[gp41] (Mus musculus) PubMed
2552.
Wild type HIV-1 reverse transcriptase (RT) indeed catalyzes incorporation of deoxynucleoside diphosphates (dNDP) substrates whereas RT with mutations of residue K65 were unable to catalyze this reaction.[Reverse transcriptase] (Mus musculus) PubMed
2553.
Derivatives of Gag p24(19-27) and Gag p17(77-85) cytotoxic T cell (CTL) epitopes are identified that induce cross reactive anti-HIV-1 CTL responses against naturally occurring mutants in lymphocytes primed ex vivo and in HLA-A2 transgenic mice in vivo. (Mus musculus) PubMed
2554.
HIV-1 glycoprotein 120 can up-regulate multidrug resistance protein Mrp1, but not Mrp4, functional expression in cultured astrocytes. [glycoprotein 120; gp120] (Mus musculus) PubMed
2555.
The solution structures of complexes between calcium-saturated calmodulin (Ca (2+)/CaM) and a CaM-binding domain of the HIV-1 matrix protein p17 have been determined by small-angle X-ray scattering.[p17] (Mus musculus) PubMed
The interactions between two beta-strands that are important for the formation and/or integrity of the beta-barrel can be supported by either a disulfide bond or beta-sheet favoring residues.[Gp120] (Mus musculus) PubMed
2558.
NMR studies show that NCp7(12-55) and NCp7(1-55) interact at the 5' end of the loop of DeltaP(-)PBS, a (-)PBS (primer-binding site) derivative without the 3' protruding sequence, in a slow-exchange equilibrium.[Ncp7] (Mus musculus) PubMed
2559.
The interaction of HIV-1 viral glycoprotein gp120 with the tyrosine-sulfated amino-terminus of human CCR5 is critical to the entry of HIV-1 into the cell, and has been characterized at the thermodynamic level. (Mus musculus) PubMed
2560.
The trimeric membrane-proximal external region structure represents the prefusion conformation of gp41, preceding the putative prehairpin intermediate and the postfusion trimer-of-hairpins structure.[gp41] (Mus musculus) PubMed
2561.
The structure of HIV-1 protease in complex with transition-state analog KNI-272 was determined by combined neutron crystallography at 1.9-A resolution and X-ray crystallography at 1.4-A resolution.[HIV-1 protease] (Mus musculus) PubMed
2562.
the RNA recognition mechanism for NCp8 is different from that of NCp7 and that the hydrophobic cleft in the second zinc finger acts as a secondary active domain instead of the 3(10) helix in NCp7 [NCp7] (Mus musculus) PubMed
2563.
Two IN dimers individually assemble on U3 and U5 DNA sequence ends before the non-covalent juxtaposition of two viral DNA ends, producing the synaptic complex.[Integrase] (Mus musculus) PubMed
2564.
The data suggest that in addition to facilitating annealing of tRNA(Lys3) to the primer binding site and possible denaturation of the primer activation signal, other functions of nucleocapsid p7 (NCp7) involved in annealing are required.[NCp7] (Mus musculus) PubMed
2565.
gp105 suppresses activation of T cells through a monocyte-mediated mechanism. The TLR4 pathway is likely involved, since gp105 activates TLR4 signaling and induces TNF-alpha production by monocytes. gp105. (Mus musculus) PubMed
2566.
results show for the first time that Vpu proteins from SIV(cpz)isolates, although diverse in sequence & predicted secondary structure from the HIV-1 subtype B protein, are capable of down-regulating CD4 [Vpu] (Mus musculus) PubMed
2567.
the accessory factor, vpr, behaves similarly to the essential lentiviral genes tat and env [vpr] (Mus musculus) PubMed
2568.
NAF may play a role in modulating host cell gene expression during MMTV infection. [NAF, negative acting factor] (Mus musculus) PubMed
2569.
Adventitial monocytes/macrophages are source of factor XIII in tissue-type transglutaminase(tTG)-null mice and contribute to an alternative, delayed mechanism of inward remodeling when tTG is absent. (Tissue-type transglutaminase, factor III) (Mus musculus) PubMed
2570.
Myostatin is dynamically regulated in the heart and acts more broadly than previously appreciated to regulate growth of multiple types of striated muscle. (Myostatin) (Mus musculus) PubMed
2571.
Recognition that p66shc conditions destiny of cardiac progenitor cells(CPCs) raises possibility that diabetic cardiomyopathy is stem cell disease in which abnormalities in CPCs define life and death of heart. (Mus musculus) PubMed
2572.
Identification of the segment of the MMTV genome which represents the binding site for Rem protein and is required for export of the unspliced viral RNA transcripts (Rem). (Mus musculus) PubMed
2573.
mutations in SU protein alter disease pathogenesis [SU protein] (Mus musculus) PubMed
2574.
RNase H primer grip is an important determinant of in vivo fidelity of DNA synthesis [reverse transcriptase (RT)] (Mus musculus) PubMed
2575.
intracellular expression of the env N-terminal heptad repeat region inhibited fusion by efficiently blocking proteolytic processing and intracellular transport of the envelope protein [env] (Mus musculus) PubMed
2576.
C-terminal disulfide-bonded loop of murine leukemia virus SU protein invovled in a postbinding step critical for viral entry [SU protein] (Mus musculus) PubMed
2577.
crystal structure at 1.6-Angstroms resolution of RNaseH was determined [RNase H] (Mus musculus) PubMed
2578.
correlate with deletion studies mapping the domain and subdomain boundaries of reverse transcriptase and integrase [RNase H and integrase] (Mus musculus) PubMed
2579.
transmembrane peptides bind to Env arrested at intermediate stage of activation by alkylation of the isomerization-active thiol in the surface subunit; this inhibits fusion rescue by dithiothreitol-mediated reduction of surface protein-TM disulfide [env] (Mus musculus) PubMed
2580.
Data indicate a possible mechanism by which the membrane-proximal domain in Moloney murine leukemia virus glycoprotein Env may affect the formation of membrane fusion intermediates. [Env] (Mus musculus) PubMed
2581.
Abl protein contribute to proper localization by playing a dominant role in trafficking of the v-Abl molecule[v-Abl protein ] (Mus musculus) PubMed
2582.
Random and site-directed mutagenesis in combination with high-temperature activity screens were used to identify multiple point mutations that collectively increase the half-life of reverse transcriptase at elevated temperature (reverse transcriptase). (Mus musculus) PubMed
2583.
NMR assignment of WT matrix protein and its R55F mutant from Mason-Pfizer monkey virus (Mus musculus) PubMed
2584.
Nucleocapsid-free dUTPase (48 426 Da) was cocrystallized with a dUTP substrate analogue using the hanging-drop vapour-diffusion method. (deoxy UTPase) (Mus musculus) PubMed
2585.
These results show clearly that the proposed redox mechanism does not rely solely on the formation of the stabilizing S-S bridge in the protease.[M-PMV protease] (Mus musculus) PubMed
2586.
The oligomeric properties of betaretroviral nonmyristoylated matrix protein (MA) and its R55F mutant from the Mason-Pfizer monkey virus in solution were studied by means of chemical crosslinking and NMR spectroscopy.[MA] (Mus musculus) PubMed
2587.
Integrase has evolved to have submaximal processing activity so that it can also catalyze DNA joining. [integrase] (Mus musculus) PubMed
2588.
the conserved 35-amino-acid spacing is not absolutely required for enzymatic activity, but the correlation between infectivity and Mg(2+)-dependent activity supports magnesium as the metal cofactor used by integrase in vivo (integrase) (Mus musculus) PubMed
2589.
We first used molecular modelling to predict that the gp30 minimal fusion peptide corresponds to the 15 first residues. (gp30) (Mus musculus) PubMed
2590.
Understanding the mechanism of how cleavage of IGFBP-5 by this protease (IGFBPase) alters its activity will help to further our understanding of the biologic actions of the IGFs [IGFBPase] (Mus musculus) PubMed
2591.
p12 could replace Nef in HIV-1, and reconstitute virus replication in HIV-1 infected Magi-CCR5 cells or macrophages. [HTLV-1p12] (Mus musculus) PubMed
2592.
p12I isdispensable for the transmission and maintenance of HTLV-I infection [P12I protein] (Mus musculus) PubMed
2593.
Data show that depletion of hCAP-D2 affects chromosome alignment in metaphase and delays entry into anaphase, suggesting that condensin I is involved in the correct attachment between kinetochores and the mitotic spindle [hCAP-D2]. (Mus musculus) PubMed
2594.
data indicate that p12I appears to play a vital role in HTLV-1-mediated T cell activation by activating calcium-mediated transcription and augmenting the amounts of p300 within T lymphocytes [p12I] (Mus musculus) PubMed
2595.
p30II functions as a novel retroviral modulator of Myc-TIP60-transforming interactions that may contribute to adult T-cell leukemogenesis. (Mus musculus) PubMed
2596.
some genetic markers were recognized in association with isolates from HTLV-1a subgroup B and Brazilian HTLV-1aA strains [p12I protein] (Mus musculus) PubMed
2597.
Results highlight the centrosome as a site to organize phosphorylation of Cep55 by Erk2/Cdk1 and Plk1, enabling it to relocate to the midbody to function in mitotic exit and cytokinesis [Cep55]. (Mus musculus) PubMed
report the structure of a complex of human T cell leukemia virus type 1 (HTLV-1) protease with a substrate-based inhibitor bound in subsites P5 through P5' (Mus musculus) PubMed
2600.
Expression of HTLV-1 Tax may lead to immune escape of infected T cells and, thus, to persistent infection and transformation. (TAX) (Mus musculus) PubMed
2601.
Growth-promoting activity of HBZ RNA likely plays an important role in oncogenesis by HTLV-I. (HBZ = basic leucine zipper factor) (Mus musculus) PubMed
2602.
HBZ was not required for in vitro cellular immortalization, but enhanced infectivity and persistence. (HBZ protein) (Mus musculus) PubMed
2603.
data show the presence of a novel isoform of HBZ in adult T-cell leukemia cells, and in addition, shed new light on the possibility that each isoform may play a unique role in distinct regions in the cell nucleus[HBZ] (Mus musculus) PubMed
2604.
Tax-mediated dendritic cell gene regulation might play a critical role in cellular activation and the mechanisms resulting in HTLV-1-induced disease. (Tax) (Mus musculus) PubMed
2605.
indicate that HTLV-1 p12(I), in addition to enhancing T cell activation, promotes cell-to-cell spread by inducing LFA-1 clustering on T cells via calcium-dependent signaling [p12I1] (Mus musculus) PubMed
2606.
Molecular analysis revealed a novel form of a single pigment gene with a unique arrangement of exon 5 (Y277 from the L gene and A285 from the M gene). (Mus musculus) PubMed
2607.
p30 nuclear/nucleolar retention is mediated through interactions with RNA and a constituent of the 60 S ribosomal subunit [gp30, HTLV-1] (Mus musculus) PubMed
2608.
tof/p30II interacts with HTLV-1 Rex protein and sequesters Rex/cellular export factor (CRM-1) complexes in the nucleoli [tof; p30II] (Mus musculus) PubMed
2609.
anti-gp46-197 antibody may be a novel beacon for gauging the efficacy of therapeutic approaches to adult T-cell leukemia/lymphoma [gp46] (Mus musculus) PubMed
2610.
results suggest that HTLV-I HBZ-SP1- mediated sequestration of JunB to the HBZ-SP1 nuclear bodies may be causing the repression of JunB activity in vivo [HBZ-SP1] (Mus musculus) PubMed
2611.
p12(I) has contrasting effects on TCR signaling: it down-regulates TCR in a LAT-dependent manner on one hand, and on the other, it increases calcium release in a LAT-independent manner.[p12(I)] (Mus musculus) PubMed
2612.
review summarizs the molecular and cellular mechanisms involved in the leukemogenesis induced by HTLV-I, focusing particularly on the viral gene HBZ(HBZ) (Mus musculus) PubMed
2613.
evidence is provided that HBZ/JunD heterodimers interact with Sp1 transcription factors and that activation of hTERT transcription by these heterodimers is mediated through binding sites for Sp1 present in the hTERT promoter.[bZIP] (Mus musculus) PubMed
2614.
a novel host-virus interaction between a cellular factor XBP-1 and transcriptional regulation of HTLV-1 [XBP-1] (Mus musculus) PubMed
2615.
Sp1 is critical for sHBZ transcription, which accounts for the constitutive expression of the sHBZ gene (Mus musculus) PubMed
2616.
Hbz expression enhances the proliferative capacity of HTLV-1-infected T cells, playing a critical role in cell survival and ultimately HTLV-1 tumorigenesis in the infected host. (Hbz) (Mus musculus) PubMed
2617.
Human T-cell leukemia virus type 1 HBZ protein bypasses the targeting function of ubiquitination [HBZ] (Mus musculus) PubMed
2618.
HBZ specifically suppressed NF-kappaB-driven transcription mediated by p65, but not the alternative pathway. HBZ binding to p65 diminished p65's DNA binding capacity and repressed its target genes. HBZ. (Mus musculus) PubMed
2619.
Expression of HBZ plays a role in pathogenesis of the HTLV-1 associated myelopathy and tropical spastic paraparesis. [HBZ] (Mus musculus) PubMed
2620.
The authors demonstrate that the repression of c-Jun activity in vivo is mainly due to the HBZ-SP1-mediated sequestration of c-Jun to the HBZ-NBs.[HBZ] (Mus musculus) PubMed
2621.
p28 function is critical for viral survival in vivo.[p28] (Mus musculus) PubMed
2622.
data indicate that VP2, a protein apparently unique to the caliciviruses, is essential for productive replication that results in the synthesis and maturation of infectious virions. [VP2] (Mus musculus) PubMed
2623.
Study reports the crystal and molecular structures of the 3C proteinase and provides insight into the mechanisms underlying the proteolysis of natural substrates by this viral cysteine peptidase. (Mus musculus) PubMed
2624.
Hepatitis A virus (HAV), a hepatotropic picornavirus, ablates type 1 interferon responses by targeting the 3ABC precursor of its 3C(pro) cysteine protease to mitochondria where it colocalizes with and cleaves MAVS.[3ABC] (Mus musculus) PubMed
2625.
there seemed to be more mutations in the strains obtained from fulminant hepatitis and acute hepatitis (AH) patients than in those obtained from AH patients in the central part of HAV 2B [HA virus protein 2b] (Mus musculus) PubMed
2626.
The expression of HAV cellular receptor, cr-1 on CD4 T cells correlated significantly with the antibody responses and cytokine levels.[cr-1] (Mus musculus) PubMed
2627.
cardioviruses target the same group of nucleoporins as enteroviruses, but the effector mechanism triggered by L (or L-Ran complexes) involves a unique cytosol-dependent phosphorylation cascade rather than proteolysis. (Mus musculus) PubMed
2628.
L protein is involved in the control of viral antiapoptotic functions. [L protein] (Mus musculus) PubMed
2629.
RNA-dependent RNA polymerase structure and complex with a template-primer RNA [RNA-dependent RNA polymerase] (Mus musculus) PubMed
2630.
certain RNA sequences within the foot-and-mouth disease virus (FMDV) 5' untranslated region but outside of the cre/bus can enhance VPg uridylylation activity[VPg] (Mus musculus) PubMed
2631.
findings suggest that phosphorylation of threonine/serine residues adjacent to the essential RNA-binding site in the auxiliary p33 protein likely plays a role in viral RNA replication and subgenomic RNA synthesis during tombusvirus infections [p33] (Mus musculus) PubMed
2632.
propose the primary function of reversible phosphorylation of p33 is to regulate RNA binding capacity of p33 which could affect assembly of viral replicase complexes, recruitment of RNA template into replication and/or release RNA from replication [p33] (Mus musculus) PubMed
2633.
as few as 3 residues of the coat protein R-domain may be sufficient for formation of T=3 particles; between 4 to 13 residues of the R-domain may be required for proper positioning of betaA and beta-annulus structural elements of the C-type subunits [cp] (Mus musculus) PubMed
2634.
The crystal structure of p21, which reveals an octameric ring architecture with a large central cavity of approximately 90 A diameter, was reported. (Mus musculus) PubMed
2635.
TGBp1 is an important symptom contributor in PVX infections [TGBp1 protein] (Mus musculus) PubMed
2636.
A revised model of the three-dimensional organization of coat protein (CP) subunits in the PVX virions is proposed. This two-domain model explains better the high plasticity of the PVX CP structure. [CP] (Mus musculus) PubMed
2637.
The 25K protein was shown to form homodimers and homooligomers (25K protein). (Mus musculus) PubMed
2638.
a Nicotiana tabacum kinase of the CK2 family is involved in TBGp1 phosphorylation during the course of viral infection [TGBp1] (Mus musculus) PubMed
2639.
C-terminal 10/18 amino acids region was not essential for virus-like particle assembly from coat protein, but virus-like particles assembled from the mutant coat protein were incapable of TGBp1 binding and being translationally activated. [TGBp1 and CP] (Mus musculus) PubMed
2640.
HCPro interferes with some of the catalytic functions of the 20S proteasome suggesting the existence of a novel type of defence and counter-defence interplay in the course of interaction between potyviruses and their hosts.[ HCPro] (Mus musculus) PubMed
2641.
interactions between the VPg and HcPro of Lettuce mosaic potyvirus (LMV) and between LMV VPg and the lettuce translation initiation factor 4E, the cap-binding protein (eIF4E), were demonstrated in vitro [VPg] (Mus musculus) PubMed
2642.
This is first report describing two distinct electrophoretic forms corresponding to phosphorylated and dephosphorylated forms of PPV capsid proteins in infected plants. [CP protein] (Mus musculus) PubMed
2643.
A virus purification protocol demonstrates the Cylindrical Inclusion protein (CI) of PVA is associated with a subpopulation of virions isolated from infected plants. [CI] (Mus musculus) PubMed
2644.
Five different amino acid substitutions in the VPg of Potato virus Y were shown to be independently responsible for virulence toward pvr2(3) resistance gene of pepper.[VPg] (Mus musculus) PubMed
2645.
dissociation constants of Tobacco etch virus protease substrate and product peptides using isothermal titration calorimetry for various forms of this enzyme[protease] (Mus musculus) PubMed
2646.
VPg inhibits cap-dependent translational initiation via binding to eIF(iso)4E [VPg] (Mus musculus) PubMed
2647.
In cap-bound eIF4E orthologues, the VPg binds to the C-terminal region, which constitutes one side of the entrance to the cap-binding pocket, whereas in cap-free state, VPg binds to the widely opened cap-binding pocket and its surrounding region.[VPg] (Mus musculus) PubMed
2648.
These results suggest that the viral replication proteins are associated with the intracellular membranes harboring TOM1 and TOM2A and that this association is important for RdRp activity. [TOM1, TOM2A] (Mus musculus) PubMed
2649.
results show a cis-preferential requirement of p88, but not of p27, for the replication of RNA1.[p88] (Mus musculus) PubMed
2650.
analysis of lytic activity of flock house virus capsid protein [capsid protein] (Mus musculus) PubMed
2651.
These data suggest that the packaging of RNA1 is dependent on trafficking of coat protein to mitochondria, the presumed site of FHV assembly, and that this trafficking requires a high density of positive charge in the N terminus. (Mus musculus) PubMed
2652.
implicate membrane phospholipids as important host determinants for FHV RNA polymerase membrane association [RNA polymerase ] (Mus musculus) PubMed
2653.
Deletion of a conserved coiled-coil domain from the 2b protein prevented its interaction with CP, whereas deletion of N- and C-terminal domains of the 2b protein greatly enhanced its interaction with CP. [2b protein] (Mus musculus) PubMed
2654.
Molecular model supports the hypothesis that BMV 1a should have helicase activity (1a replicase). (Mus musculus) PubMed
2655.
A highly conserved cis-acting 3' tRNA-like structure is required for the packaging of B3 in vivo, but not for B1 or B2. [B3, B2, & B1] (Mus musculus) PubMed
2656.
study tested the assumption that phosphorylation may be a mechanism that regulates B3a movement protein functions and showed that not only B3a but also the coat protein, BCP, was phosphorylated in BMV-infected barley protoplasts. [B3a, BCP] (Mus musculus) PubMed
2657.
we have created partial protein models for the region surrounding residue 461 of 1a protein which can account structurally for the effect of aa 461 on elicitor function in the hypersensitive response [1a protein] (Mus musculus) PubMed
2658.
These results suggest that Tcoi1 controls the propagation of CMV through an interaction with the CMV 1a protein.[Cucumber mosaic virus 1a protein] (Mus musculus) PubMed
2659.
The results indicate that TGB2 and gammab proteins play a previously unknown functional role at the site of virus replication.[triple-gen block 2 protein] (Mus musculus) PubMed
2660.
These experiments suggest that BSMV movement requires physical interactions of TGB2 and TGB3 and that substantial deviation from the TGB protein ratios expressed by the wild-type virus compromises movement.[TGB2 and TGB3] (Mus musculus) PubMed
2661.
the ORF3 protein exploits the endosomal sorting machinery to enhance the secretion of an immunosuppressant molecule (alpha1 microglobulin) from cultured hepatocytes [ORF3] (Mus musculus) PubMed
2662.
when expressed through baculovirus, the ORF1 polyprotein was processed into smaller proteins that correlated with their proposed functional domains; this processing mainly depended upon a cysteine protease [ORF1] (Mus musculus) PubMed
2663.
in contrast to its requirement in vivo, ORF3 protein is not required for infection of Huh-7 cells or production of infectious virus in vitro (ORF3 protein) (Mus musculus) PubMed
2664.
defines the pathway by which ORF2 obtains access to the cytoplasm[ORF2 protein] (Mus musculus) PubMed
2665.
hepatitis E virus Orf3 protein protects cells from mitochondrial depolarization and death [Orf3] (Mus musculus) PubMed
2666.
A potential oral vaccine is provided by virus-like particles formed by a protein construct of partial ORF3 protein (residue 70-123) fused to the N-terminus of the ORF2 protein (residues 112-608). (hepatitis E virus ORF3 and ORF2 proteins) (Mus musculus) PubMed
2667.
The authors propose that through its effects on EGFR trafficking, pORF3 prolongs endomembrane growth factor signaling and promotes cell survival. The effects on STAT3 translocation would result in a reduced inflammatory response. (Mus musculus) PubMed
2668.
ORF3 protein, at least its C-terminal portion, is present on the surface of HEV virions released from infected cells. [ORF3] (Mus musculus) PubMed
2669.
The ORF3-fibrinogen Bbeta interaction was verified by co-immunoprecipitation and fluorescence resonance energy transfer in mammalian cells. (Mus musculus) PubMed
2670.
These results suggest that the ORF3 protein is responsible for virion egress from infected cells and is present on the surface of released hepatitis E virus particles, which may be associated with lipids.[Orf3] (Mus musculus) PubMed
2671.
HEV ORF3 product localizes to microtubules and interferes with their dynamics. vp13 led to elevation of acetylated alpha-tubulin. [vp13] (Mus musculus) PubMed
2672.
The results showed that HIF-1alpha, a highly unstable subunit of the HIF-1, was stabilized in hepatitis E virus ORF3-expressing cells.[ORF3] (Mus musculus) PubMed
2673.
we report for the first time the crystal structure of the HEV capsid protein domain E2s (Mus musculus) PubMed
2674.
Endoplasmic reticulum stress and nfkb activation initiates the signal for inducing Hepatitis D LDAg translocation to cytoplasm by Hepatitis b virus surface antigens [LDag] (Mus musculus) PubMed
2675.
data suggest that a protonated base triple allows the WT ribozyme to maintain appreciable activity at acidic pH, which could play an important role in the life cycle of the virus[HDV ribozyme] (Mus musculus) PubMed
2676.
Comparison of a systematic set of cis- and trans-acting HDV ribozymes shows that the absence of either L4 or J1/2 significantly and independently impacts catalytic activity [ribozyme] (Mus musculus) PubMed
2677.
the structure of native JcDNV at 8.7A resolution and of the two VLPs formed essentially from VP2 and VP4 at 17 A resolution, as determined by cryo-electron microscopy [VP2 & VP4] (Mus musculus) PubMed
2678.
sequence critical for P9-driven expression identified within the overlapping 3' coding region of the viral capsid protein and non-structural genes [P9] (Mus musculus) PubMed
2679.
This study demonstrates the significance of VP2 in CAV replication and shows that specific mutations introduced into the gene encoding this protein can reduce virus replication, cytopathogenicity and downregulation of MHC I in infected cells. [VP2] (Mus musculus) PubMed
2680.
describes the substrate preferences and determinants of specificity for the dengue virus NS2B(H)-NS3pro protease [NS3, dengue virus] (Mus musculus) PubMed
2681.
the neutralizing epitopes of the DENV-2 Domain III to its specific neutralization antibody (mAb 137-22) by site-directed mutagenesis (Mus musculus) PubMed
2682.
envelope protein fusion peptide - mutation impairs fusion efficiency and reduces virus reactivity with flavivirus group-reactive antibodies (Mus musculus) PubMed
2683.
Core protein major features are a human HBV core protein-like two-domain structure with an assembly domain comprising the first about 185 amino acids and a C-terminal nucleic acid binding domain, connected by a morphogenic linker region.[core protein] (Mus musculus) PubMed
2684.
The inhibitory effect of DHBe on infection could play a role in maintaining viral persistence. [E antigen] (Mus musculus) PubMed
2685.
These findings identify E163 as a new chemokine binding protein in poxviruses and provide a molecular mechanism for the immunomodulatory activity previously reported for the vaccinia virus A41 ortholog.[E163] (Mus musculus) PubMed
2686.
The type I interferon (IFN) binding protein (bp) of ECTV, is essential for ECTV virulence and is a natural target of the antibody response.[type I IFN binding protein] (Mus musculus) PubMed
2687.
Data show that ectromelia virus CD30 is expressed as a secreted disulfide linked trimer and that the absence of vCD30 does not impair mousepox induced fatality in vivo [CD30]. (Mus musculus) PubMed
2688.
The M2-2 protein expressed at a high level completely inhibited respiratory syncytial virus replication. (M2-2 protein) (Mus musculus) PubMed
2689.
this paper shows that Fbl is a fibrinogen-binding adhesin and a clumping factor [Fbl] (Mus musculus) PubMed
2690.
AtlL is the first autolysin described in S. lugdunensis, with a bifunctional enzymatic (N-acetylglucosaminidase and N-acetylmuramoyl-l-alanine amidase activities) in peptidoglyan hydrolysis. [AtlL] (Mus musculus) PubMed
2691.
study suggests that 2b in PRRSV is similar to the E protein in equine arteritis virus and forms a minor structural component of the virion [2b protein] (Mus musculus) PubMed
2692.
Results report the crystal structure of nsp1alpha of PRRSV, and suggest that it functions differently from other reported viral leader proteases, such as that of foot-and-mouth disease [Nsp1alpha]. (Mus musculus) PubMed
2693.
The triple gene block protein 1 (TGBp1) encoded by Plantago asiatica mosaic virus (PlAMV), exhibited a strong suppressor activity, on the accumulation of microRNA, virus genomic RNA and virus-derived small interfering RNAs. [TGBp1] (Mus musculus) PubMed
2694.
v-slfn is an orthopoxvirus virulence factor that affects the host immune response to infection.[v-slfn] (Mus musculus) PubMed
2695.
SseF interacts functionally and physically with SseG but not SifA and is also required for the perinuclear localization of Salmonella vacuoles. (SseF)(SseG) (Mus musculus) PubMed
2696.
O-antigen contains repeating unit of ribitol phosphate and 2-acetimidoylamino-2,6-dideoxy-L-galactose. [O-antigen] (Mus musculus) PubMed
2697.
a functional role to the Salmonella effector SlrP as a binding partner and an E3 ubiquitin ligase for mammalian thioredoxin [SlrP] (Mus musculus) PubMed
2698.
induced within macrophages by phagosome acidification; may play a role in the establishment of the intracellular replication niche [virulence factor A; bvfA] (Mus musculus) PubMed
2699.
these results suggest that Brucella T4SS VirB is not involved in the control of dendritic cells maturation and does not interfere with the establishment of a T-helper type 1 adaptive immune response.[VirB in strain ATCC 23444] (Mus musculus) PubMed
2700.
Small-angle X-ray scattering analysis of Rhodothermus marinus Cel12A showed that the enzyme forms a loosely associated antiparallel dimer in solution, which may target the enzyme to the antiparallel polymer strands in cellulose [Cel12A] (Mus musculus) PubMed
2701.
Single-subunit Na+/H+ antiporter NhaE from Rhodothermus marinus nqoB operon of complex I is functional regarding sodium translocation, except at alkaline pH. (NhaE) (Mus musculus) PubMed
2702.
Data show that the contribution of the trehalose transporter is important only in trehalose-poor environments, and that at higher concentrations trehalose is assimilated primarily via trehalase and the glucose transport system [trehalase] (Mus musculus) PubMed
2703.
X-ray diffraction data for a cytochrome c were collected to 1.23 A resolution using synchrotron radiation and a wavelength of 0.93 A. [14kDa cyt c] (Mus musculus) PubMed
2704.
Thermophilic endo-1,3(4)-beta glucanase (laminarinase) from Rhodothermus marinus was crystallized.[endo-1,3(4)-beta glucanase] (Mus musculus) PubMed
2705.
shared activity of HPV-16 E7 and HPV-6 E7 to destabilize p130 and decrease or delay differentiation may be related to the role of E7 in the HPV life cycle [E7 protein] (Mus musculus) PubMed
2706.
The E2-DNA complex results in considerable bending of the DNA, which is facilitated by sequences with A:T-rich spacers that adopt a pre-bent conformation (E2 protein). (Mus musculus) PubMed
2707.
analysis of complex formation and catalytic activation by the PII signaling protein of N-acetyl-L-glutamate kinase from Synechococcus elongatus strain PCC 7942 [PII signaling protein] (Mus musculus) PubMed
2708.
For nitrate reductase complementary spectroscopic studies suggest a structural context for the activation[nitrate reductase ] (Mus musculus) PubMed
2709.
The proposed binding mode of KaiB explains the observation of simultaneous binding of KaiA and KaiB to KaiC, and provides insight into the mechanism of KaiB's antagonism of KaiA.[KaiB, KaiC] (Mus musculus) PubMed
2710.
RpaB interacts with a high light regulatory 1 element of several high light-responsive promoters. Under normal light conditions RpaB functions as a repressor, but its activity is weakened during high light stress. [RpaB] (Mus musculus) PubMed
2711.
The C-terminal loops of KaiC, the "A-loops", are the master switch that determines overall KaiC activity.[KaiC] (Mus musculus) PubMed
2712.
high-resolution structures of KaiA, KaiB, and KaiC suggest a ratcheting mechanism by which the KaiABC oscillator ticks unidirectionally[review][KaiA,KaiB, KaiC] (Mus musculus) PubMed
2713.
Data show that the non-conserved C-terminus of Synechococcus elongatus N-acetylglutamate kinase (NAGK) enhances arginine inhibition and holds most of the differences between S. elongatus and Arabidopsis NAGK with respect to arginine sensitivity [NAGK]. (Mus musculus) PubMed
2714.
morphological and behavioral differences in septin rings require the Elm1p and Gin4p kinases.[Elm1, Gin4] (Mus musculus) PubMed
2715.
Murine gammaherpesvirus 68 (gammaHV68) v-cyclin and v-bcl-2 genes are required for the efficient induction of gammaHV68-associated atypical lymphoid hyperplasia in BALB beta(2)m(-/-) mice. [v-Bcl-2] (Mus musculus) PubMed
2716.
Our results for MHV-68 ORF64, ubiquitin-specific protease (USP), are consistent with an enzymatic function of the tegument protein that is beneficial to the virus during acute infection, particularly in vivo. [USP] (Mus musculus) PubMed
2717.
The SVV immediate-early gene 62 (IE62) product transactivates ORF 28 and 29 expression, and a cellular upstream stimulatory factor-binding site is important for efficient IE62 induction of genes 28 and 29. [ORF 29 (Dna-binding protein), IE62] (Mus musculus) PubMed
2718.
These findings indicate that the defective presentation of class I MHC antigen on hepatocytes transcribing WHV is a consequence of posttranscriptional suppression exerted by virus pre-S2 protein and can be fully reversed by IFN-gamma. [Pre-S2 protein] (Mus musculus) PubMed
2719.
One interpretation of these data is that host range specificity of HDV is determined entirely by pre-S1 and that the woodchuck hepatitis virus and Hepatitis B virus pre-S1 proteins recognize different receptors on primary human hepatocytes. (Mus musculus) PubMed
2720.
Mutation analysis of the helicase-like domain of BaMV replicase possessing RNA 5'-triphosphatase and NTPase activities suggests that the activities are required for BaMV survival. [RNA 5'triphsophatase/NTPase] (Mus musculus) PubMed
2721.
These results raise the possibility that TGBp2 facilitates intracellular delivery of viral RNA through non-specific protein-RNA interaction.[TGBp2] (Mus musculus) PubMed
2722.
N-terminal region of NSm, which includes domain I and part of domain II, is required for virus assembly and the C-terminal hydrophobic domain V may function as an internal signal sequence for the Gc glycoprotein. (Mus musculus) PubMed
2723.
Receptor Binding Protein structure of the temperate phage TP901-1 [RBP] (Mus musculus) PubMed
2724.
the expression of pilA, which encodes the pilistructural protein, is directly regulated by a two-component regulatory system in which PilR functions as an RpoN-dependent enhancer binding protein [PilR] (Mus musculus) PubMed
2725.
MacA is not directly involved in electron transfer to Fe(III). [MacA] (Mus musculus) PubMed
2726.
structure solved by Fe SAD using data collected to a resolution of 1.86 A. In crystal, packing interactions in 1 dimension were exclusively mediated through Strep-tag II sequence. Tag & linker regions were in contact with 3 further monomers of OmcF[OmcF] (Mus musculus) PubMed
2727.
Outer membrane cytochrome c, OmcF, from Geobacter sulfurreducens shows high structural similarity to an algal cytochrome c6.[OmcF] (Mus musculus) PubMed
2728.
structural and biochemical characterization of the globin domain of the globin coupled sensors from Geobacter sulfurreducens (GsGCS(162)) is reported (Mus musculus) PubMed
2729.
Data suggest that the new type multihaem cytochroms are formed with domains homologous to the trihaem cytochrome c7: [cytochrome c7] (Mus musculus) PubMed
2730.
data show that CcpA variants S134P/V135K and S134P led to a distortion of the loop region, accompanied by an opening of the active-site loop, leaving the enzyme in a constitutively active state [Ccpa] (Mus musculus) PubMed
2731.
1.6 A crystal structure of a KinI motor core; results of this study confirm the suspected importance of loop 2 for KinI function, and provide evidence that KinI is specialized to hydrolyze ATP after initiating depolymerization [KinI] (Mus musculus) PubMed
2732.
Vps4 mediates multivesicular body formation [Vps4] (Mus musculus) PubMed
2733.
PSAC is a target for antimalarial development. (plasmodial surface anion channel) (Mus musculus) PubMed
2734.
PFB0150. Putative Ser-Thre kinase. AA 26-55 bind to band protein 4.1. (Mus musculus) PubMed
2735.
Data suggest that calcium-dependent protein kinase 1 belongs to a novel class of proteins whose export is dependent on a 'non-classical' pathway involving N-myristoylation/palmitoylation [cdpk1] (Mus musculus) PubMed
2736.
cloning and expression analysis of dihydroorotase, orotate phosphoribosyltransferase, and OMP decarboxylase (Orotidine Phosphate Carboxy-Lyase, also called OMP Decarboxylase) (Mus musculus) PubMed
2737.
P. falciparum expresses the proteins Pdx1 and Pdx2, corresponding to the yeast enzymes Snz1-p and Sno1-p, which are essential for the vitamin B6 biosynthesis [pdx2] (Mus musculus) PubMed
2738.
A nested polymerase chain reaction (PCR) using allele-specific primers for merozoite surface protein-2 gene was used to determine the parasite diversity of Plasmodium falciparum causing cerebral malaria. [msp-2] (Mus musculus) PubMed
2739.
analysis of Plasmodium falciparum cytoadherence-linked asexual protein 3 (CLAG 3) sequences that specifically bind to C32 cells and erythrocytes [CLAG3] (Mus musculus) PubMed
2740.
identified two genes, H101 and H103, related to MSP3; H101 and H103 are expressed during the asexual cycle and immunofluorescence indicates H103 localises to the merozoite surface as a peripheral membrane protein[H101, H103] (Mus musculus) PubMed
2741.
var2CSA is transcriptionally up-regulated in CSA-binding parasites; CSA-binding domains in var2CSA defined [var2CSA] (Mus musculus) PubMed
2742.
identification of a second copy of the small subunit gene, termed PfR4, encoding a 324 amino acid residue polypeptide that shares only 25% identity with the previously identified PfR2 small subunit of Plasmodium falciparum [PfR2 and PfR4] (Mus musculus) PubMed
2743.
detection of translation of the tufA gene encoded by the Plasmodium falciparum apicoplast genome [tufA] (Mus musculus) PubMed
2744.
High prevalence of Plasmodium falciparum pfcrt K76T mutation in pregnant women taking chloroquine prophylaxis in Senegal. [pfcrt] (Mus musculus) PubMed
2745.
enzyme activation of hypoxanthine guanine phosphoribosyltransferase is effected by the product, inosine monophosphate (IMP), and not by the substrates [HGPRT] (Mus musculus) PubMed
2746.
identified and characterized an immunophilin of the FKBP family, FKBP35; it's an essential parasitic chaperone with a novel drug-independent calcineurin-inhibitory activity [FKBP35] (Mus musculus) PubMed
2747.
hemoperoxidase has a role in P. falciparum growth, as shown when its inhibition by clotrimazole leads to oxidative stress (Mus musculus) PubMed
2748.
analysis of TBP-TFIIB complex structure from Plasmodium falciparum [TBP] (Mus musculus) PubMed
2749.
NIMA-related kinase NEK-4 plays an essential role in zygote-to-ookinete transformation by regulating the DNA replication that precedes meiosis. {NEK-4; NIMA-related protein kinase 4) (Mus musculus) PubMed
2750.
Plasmodium falciparum chloroquine resistance transporter (pfcrt) is involved in carrier-mediated chloroquine efflux from resistant cells. (Plasmodium falciparum chloroquine resistance transporter; pfcrt) (Mus musculus) PubMed
2751.
The molecular characterization of a novel cyclic nucleotide PDE (phosphodiesterase), isolated from the human malaria parasite P. falciparum and designated PfPDE1.[PfPDE1] (Mus musculus) PubMed
2752.
comparison of two structures, one with an empty nucleoside-binding site and a sulfate ion bound in the phosphate-binding pocket and one with substrate inosine bound reveals changes in the active site upon ligand binding (purine nucleoside phosphorylase) (Mus musculus) PubMed
2753.
upregulation of PfRH4 expression in the subclone Dd2(NM) suggests its role in erythrocyte invasion through the sialic acid independent pathway of Dd2(NM)[RH4] (Mus musculus) PubMed
2754.
structure of ribose 5-phosphate isomerase has been determined by molecular replacement at 2.09 angstroms resolution [ribose 5-phosphate isomerase] (Mus musculus) PubMed
2755.
biosynthesis of GAP45 and identify acylation by both myristoylation and palmitoylation as potentially important modifications of this protein [GAP45] (Mus musculus) PubMed
2756.
PfPKB is a protein kinase B-like enzyme from Plasmodium falciparum (Mus musculus) PubMed
2757.
The morphologies of erythrocytic falcipain-1 and falcipain-2' knockout parasites were indistinguishable from those of wild-type parasites. [falcipain-1, falcipain-2'] (Mus musculus) PubMed
2758.
Plasmodium falciparum chloroquine resistance marker protein (Pfcrmp) may be a chlroquine target protein in nucleus and that chloroquine resistance in malaria parasites may be caused by genetic alterations in Pfcrmp gene. [Pfrcmp] (Mus musculus) PubMed
2759.
provide solid evidence for the uptake of diverse solutes via plasmodial surface anion channel and implicate one or more parasite genes in expression of this channel[ plasmodial surface anion channel ] (Mus musculus) PubMed
2760.
Parasites with MSP-1(19) haplotypes different from that of the leading vaccine strain were consistently the most prevalent at a vaccine trial site. (Mus musculus) PubMed
2761.
Dead-box helicase 60kda in size shows ATP and Mg2+ dependent DNA unwinding, ssDNA-dependent ATPase and ATP-binding activities at wide ph and is schizont stage specific. [PfDH60] (Mus musculus) PubMed
2762.
Helicase 45 is an indispensable enzyme that is essential for growth, and probably survival, of P. falciparum (helicase 45). (Mus musculus) PubMed
2763.
These studies demonstrate the characterization of the catalytic subunit of signal peptidase complexSPC from P. falciparum. [SP21] (Mus musculus) PubMed
2764.
Cargo-binding function of Sec24 is conserved and that accumulation of cargo in discrete endoplasmic reticulum sites depends upon positive sorting signals. [Sec24] (Mus musculus) PubMed
2765.
The parasites successively and spontaneously switched to transcribe a shared var-gene (var2csa) matched by the loss of PfEMP1 surface expression and host cell-binding.[var2csa] (Mus musculus) PubMed
2766.
Upon ligand binding, several conformational changes occur in PfFKBD, including aromatic residues that shape the FK506 binding pocket as shown by NMR studies (Mus musculus) PubMed
2767.
ring exported protein 1 targeting to the Maurer's clefts is mediated by a two-phase process [REX1] (Mus musculus) PubMed
2768.
Study shows that the merozoite-acquired RhopH complex (comprising RhopH1, RhopH2, and RhopH3)is transferred to defined domains of the red blood cell cytoplasm, and possibly transiently associated with Maurer's clefts.[RhopH1, RhopH2, RhopH3] (Mus musculus) PubMed
2769.
ORC5 forms distinct nuclear foci colocalized with the PCNA and co-immunoprecipitates with PCNA during early-to-mid trophozoite stage replicating parasites. [ORC5] (Mus musculus) PubMed
2770.
These studies reveal the importance of the REX1 protein in determining the ultrastructure of the Maurer's cleft system. (Mus musculus) PubMed
2771.
These data implicate an important role for SERA5 in the regulation of the intraerythrocytic development of late-stage parasites and as a target for drug development.[SERA5] (Mus musculus) PubMed
2772.
two substrates of Plasmodium falciparum CDPK1: myosin A tail domain-interacting protein (MTIP) and glideosome-associated protein 45 (GAP45), both of which are components of the motor complex (Mus musculus) PubMed
2773.
RON2 forms a complex with AMA1 in Plasmodium falciparum merozoites, indicative of a fundamental role in host cell invasion. forms a complex with AMA1 in Pf merozoites. (Mus musculus) PubMed
2774.
The distribution of the 130 kDa Maurer's cleft protein changes from within the parasite to the clefts during intracellular RBC development as the parasite matures from young trophozoite to segmented schizont. [130kda Maurer's cleft protein] (Mus musculus) PubMed
2775.
The biochemical characterization and elucidation of molecular mechanisms involved in the regulation of PfCDPK4, is reported.[PfCDPK4] (Mus musculus) PubMed
2776.
Purified immunoglobulin G raised in rabbits against the binding domain of PfRh4 blocked the binding of native PfRh4 to the surfaces of erythrocytes and inhibited erythrocyte invasion. (Mus musculus) PubMed
2777.
The plasmodial surface anion channel may be encoded by multiple parasite genes and has a Complex inheritance pattern. [PSAC] (Mus musculus) PubMed
2778.
Results describe the mechanism of the metal dependency of arginase by means of homology modelling and molecular dynamics [arginase]. (Mus musculus) PubMed
2779.
Der1-1 and Uba1 (homologues of yeast ERAD components) localize to the apicoplast. [Uba1] (Mus musculus) PubMed
2780.
Longin domain is required for both endoplasmic reticulum and Golgi apparatus recycling of Sec22. [Sec22] (Mus musculus) PubMed
2781.
zfPDYN cDNA codes for a polypeptide of 252 amino acids that contains the consensus sequences for four opioid peptides: an Ile-enkephalin, the neo-endorphins, dynorphin A and dynorphin B. (Mus musculus) PubMed
2782.
the transient expression of purpurin protein was greatly different during development and optic nerve regeneration. (Mus musculus) PubMed
2783.
the Asian strain viral precursor protein E3E2 is cleaved most efficiently by furin and PC5A. This cleavage was also observed in CHIKV-infected cells and could be blocked by furin inhibitor decanoyl-RVKR-chloromethyl ketone [E2 surface glycoprotein] (Mus musculus) PubMed
2784.
may induce gp130 signaling by an exclusively autocrine mechanism that relies on intracellular binding to its receptor (interleukin-6) (Mus musculus) PubMed
2785.
role in the segregation of equivalent amounts of viral genomes tethered with LANA into two daughter progeny cells during cell division [LANA(latency associated nuclear antigen)] (Mus musculus) PubMed
2786.
ORF57 and hnRNP K interaction may modulate ORF57-mediated regulation of viral gene expression [ORF57] (Mus musculus) PubMed
2787.
LANA expression protects lymphoid cells from p16 INK4a-induced cell cycle arrest and induces S-phase entry.[LANA] (Mus musculus) PubMed
2788.
role for the inverted repeat in LANA1 binding to KSHV DNA [LANA1 (latency- associated nuclear antigen 1)] (Mus musculus) PubMed
2789.
a latent KSHV gene product, kaposin B, increases the expression of cytokines by blocking the degradation of their messenger RNAs [kaposin B] (Mus musculus) PubMed
2790.
study demonstrates that LANA physically associates with RBP-Jkappa in vitro and in KSHV-infected cells, with the complex formed capable of binding to RBP-Jkappa cognate sequences [LANA] [RBP-Jkappa] (Mus musculus) PubMed
2791.
DNase and host shutoff activities of SOX are genetically separable. [SOX protein] (Mus musculus) PubMed
2792.
findings demonstrate that the proposed leucine zipper region of K-bZIP (amino acids 182 to 218) is required for multimer formation but that it does not fold as a coiled coil[K-bZIP protein] (Mus musculus) PubMed
2793.
findings showed that MIR1 promoted down-regulation of HLA-B7 molecules lacking lysine residues in their intracytoplasmic domain [MIR1] (Mus musculus) PubMed
2794.
These data indicate that vFLIP uses TRAF2 and TRAF3 for signalling to NF-kappaB, which is crucial for KSHV-associated lymphomagenesis [vFLIP] (Mus musculus) PubMed
2795.
Kaposi's sarcoma-associated herpesvirus complement control protein (KCP) binds to heparin at physiological ionic strength. (KCP) (Mus musculus) PubMed
2796.
findings show that N-terminal LANA docks onto chromosomes by binding nucleosomes through the folded region of histones H2A-H2B (Mus musculus) PubMed
2797.
vIRF-2 protein is an interferon induction antagonist that acts pleiotropically, presumably facilitating KSHV infection and dissemination in vivo. [IRF-2] (Mus musculus) PubMed
2798.
Promoter switching allows simultaneous transcription of LANA and K14/vGPCR [LANA] (Mus musculus) PubMed
2799.
The acidic-repeat region of LANA-1 could function as an in cis-acting inhibitor of antigen presentation, which may contribute to the immune evasion of cells latently infected by KSHV. (Mus musculus) PubMed
2800.
three NLSs identified in ORF57 provide at least two functions, nuclear localization of ORF57 and up-regulation of ORF59 expression.(ORF57) (Mus musculus) PubMed
2801.
The latency-associated nuclear antigen (LANA) directly associated with a low oxygen responder, hypoxia-inducible factor-1 alpha (HIF-1 alpha). (LANA) (Mus musculus) PubMed
2802.
UNG2 binds to the carboxyl terminus of LANA and retains its enzymatic activity in the complex.[LANA] (Mus musculus) PubMed
2803.
gpK8.1 interaction with human fibroblasts induces antiviral response, as characterized by the activation of interferon regulatory factor 3 (IRF-3), production of interferon beta (IFN-beta), and expression of interferon-stimulated antiviral genes.[gpK8.1] (Mus musculus) PubMed
2804.
LANA associated with repressed cellular promoters, recruited Dnmt3a to DNA, and facilitated de novo promoter methylation of a down-regulated gene, cadherin 13 (H-cadherin). [LANA] (Mus musculus) PubMed
2805.
Hx8 appears to exert a key role in receptor stabilization through the conserved residue R7.61, directing the ligand binding profile of ORF74 and likely also that of other class A G-protein-coupled receptors [ORF74] (Mus musculus) PubMed
2806.
For virus replication to take over Kaposi sarcoma cell and produce lytic infection requires that viral gene expression of ORF57 outpace that of the host cell. [KSHV ORF57 (open reading frame 57)] (Mus musculus) PubMed
2807.
the KRAB-containing zinc finger protein K-RBP can suppress RTA-mediated transactivation and KSHV lytic replication and KSHV utilizes this protein as a regulator to maintain a balance between latency and lytic replication [K-RBP] (Mus musculus) PubMed
2808.
Results show that the LANA1 QED-rich central repeat (CR) region, particularly the CR2CR3 subdomain, retards LANA1 synthesis and markedly enhances LANA1 stability in vitro and in vivo, similar to the Epstein-Barr virus nuclear antigen-1 [LANA1] (Mus musculus) PubMed
2809.
We also show that RTA regulates ORF59 promoter through interaction with RBP-Jkappa as well as a cis-acting RTA responsive element within the promoter. [ORF59] (Mus musculus) PubMed
2810.
latency-associated nuclear antigen itself was localized mainly to the nuclear matrix fraction but also that TR region of the KSHV genome existed together in the G1 phase [latency-associated nuclear antigen ] (Mus musculus) PubMed
2811.
Late tumour stages of Kaposi sarcoma in tissues from HIV-positive patients are associated with high levels of LANA-1, HIF-1alpha and of the anti-apoptotic proteins, Bcl-2 and Mcl-1 [LANA-1]. (Mus musculus) PubMed
2812.
GBV-B has an analogous p7 protein to HCV p7 [p7 protein] (Mus musculus) PubMed
2813.
The characterization of the targeting and insertion of p36 into the mitochondrial outer membrane also sheds light on the mechanisms involved in sorting of host-cell membrane proteins to mitochondria. (Mus musculus) PubMed
2814.
Rv-cyclin down regulates NF-kappaB-dependent transcription, whether induced by TNFalpha or by direct phosphorylation of IkappaB by expressed MEKK1.[rv-cyclin] (Mus musculus) PubMed
2815.
Duplicate open reading frames ( Rf-1A and Rf-1B) with a pentatricopeptide (PPR) motif were cloned; it is concluded that Rf-1A is the Rf-1 gene [Rf-1A] (Mus musculus) PubMed
2816.
OsCRL4 represents a new member of the cytokinin receptor protein in rice. [CRL4] (Mus musculus) PubMed
2817.
upregulation of OsSBP expression conferred enhanced tolerance to different pathogens, possibly by increasing plant sensitivity to endogenous defense responses [OsSBP] (Mus musculus) PubMed
2818.
differential expression of SIG genes in leaf morphogenesis, suggesting the existence of tissue- and stage-specific functions of SIG proteins for transcriptional regulation of chloroplast genes in plant development [SIG1], [SIG2A] (Mus musculus) PubMed
2819.
Genes catalyze sequential cyclization steps in momilactone diterpenoid biosynthesis and seem to have been evolutionarily coupled by physical linkage and resulting cosegregation. [OsDTS2] (Mus musculus) PubMed
2820.
The gene for OsMADS18 protein is expressed in rice (OsMADS18), overinduction leading to early flowering.[OsMADS18] (Mus musculus) PubMed
2821.
Telomerase reverse transcriptase (OsTERT) contains at least five alternatively spliced transcripts and two putative phosphorylation sites for Akt kinase [OsTERT] (Mus musculus) PubMed
2822.
OsENT2 mediates adenosine transport, but has brooad substrate specificity (equilibrative nucleoside transporter 2) (Mus musculus) PubMed
2823.
results indicate that OsGNA1 is required for maintaining normal root cell metabolism and cell shape [glucosamine-6-P acetyltransferase, OsGNA1] (Mus musculus) PubMed
2824.
Al-resistant seedlings and Al-sensitive seedlings segregated at a 3 : 1 ratio, indicating that the high sensitivity to Al in als1 is controlled by a single recessive gene. The gene was mapped to the long arm of chromosome 6. [als1] (Mus musculus) PubMed
2825.
The mutant of rice (Oryza sativa L. ssp. indica cv IR8) arm2 is defective in the uptake of the naturally occurring auxin indole-3-butyric acid (IBA) [ARM2] (Mus musculus) PubMed
2826.
The pms3 (a gene for photoperiod-sensitive genic male sterility) locus was assigned to a 28.4-kb DNA fragment by chromosome 12 genetic and physical mapping. (Mus musculus) PubMed
2827.
The upregulation of RERJ1 in response to wounding and water stress is reported. [RERJ1] (Mus musculus) PubMed
2828.
The effects of overexpression as well as insertional mutagenesis of the rice two-pore channel 1 (OsTPC1), a putative voltage-gated Ca(2+)-permeable channel, on a proteinaceous fungal elicitor-induced defense responses in rice cells is reported. [TPC1] (Mus musculus) PubMed
2829.
Spontaneously occurring mutations in the CPD photolyase gene cause different degrees of sensitivity to UVB in rice. (Mus musculus) PubMed
2830.
data suggest that OsSERK1 may partially mediate defense signal transduction in addition to its basic role in somatic embryogenesis [SERK1] (Mus musculus) PubMed
2831.
cloning of the R gene Xa27 from rice and the cognate avr gene avrXa27 from Xanthomonas oryzae pv. oryzae [Xa27] (Mus musculus) PubMed
2832.
Possible functions of the GYM (gypsy embryo) gene and the ovule developmental mechanism are discussed.[GYM] (Mus musculus) PubMed
2833.
The htd-1 mutant increases its tiller number by releasing axillary buds from dormant stage rather than by initiating more axillary buds. By map-based cloning, the htd1 gene was fine mapped in a 30-kb DNA region on chromosome 4 (htd1). (Mus musculus) PubMed
2834.
The OsBIHD1 protein may be positively involved in activating expression of the defence-related genes in disease resistance responses, and is also important in rice development and abiotic stress tolerance. (Mus musculus) PubMed
2835.
The isolation and characterization of 4 DCL proteins in O. sativa is reported. [DCL1; DCL2; DCL3; DCL4] (Mus musculus) PubMed
2836.
Pi36(t) is a novel rice blast resistance gene located on rice chromosome 8 [Pi36(t)] (Mus musculus) PubMed
2837.
SKC1 is involved in regulating K(+)/Na(+) homeostasis under salt stress. (SKC1) (Mus musculus) PubMed
2838.
OsBIHD1 is a BELL type of homeodomain transcription factor present in the nucleus, whose induction is associated with resistance response in rice.[BIHD1] (Mus musculus) PubMed
2839.
DBS1 encodes a NACK-type kinesin-like protein (OsNACK); dbs1 mutation causes a severe defect in DBS1 function but does not completely shut it down. [dbs1] (Mus musculus) PubMed
2840.
isolated a putative transcription factor designated OsCBT; results suggest that OsCBT is a transcription activator modulated by calmodulin [CBT] (Mus musculus) PubMed
2841.
GID1 is a soluble receptor mediating gibberellin signalling in rice [GIBBERELLIN INSENSITIVE DWARF1 = GID1] (Mus musculus) PubMed
2842.
proposed that OsGAP1 facilitates vesicular trafficking from the trans-Golgi network to the plasma membrane or central vacuole by both stimulating the GTPase activity of OsRab11 and increasing the recycling of inactive OsRab11 [GAP1] (Mus musculus) PubMed
2843.
OsZIP4 is a Zn transporter that may be responsible for the translocation of Zn within rice plants. (Mus musculus) PubMed
2844.
A defect in the cytosolic AGPase small subunit2b transcription from the AGPS2 gene in endosperm sharply enhanced the expressions of endosperm and leaf plastidial AGPS1, the endosperm cytosolic AGPase large subunit2 (AGPL2), and the leaf plastidial AGPL1. (Mus musculus) PubMed
2845.
These data suggest that the RMtATP6 protein acts as a subunit of ATP synthase, and is expressed in response to stress from several salts [RMtATP6]. (Mus musculus) PubMed
2846.
Sequence comparison analysis reveals that the six paralogs at the Pi9 locus belong to four classes and gene duplication took place to form the gene cluster. Nbs2-Pi9 is the Pi9 gene. (Pi9) (Mus musculus) PubMed
2847.
a single recessive gene, tentatively designated as bph19(t), conditioned the resistance against brown planthopper.The bph19(t) locus was physically defined to an interval of about 60 kb.[BPH19] (Mus musculus) PubMed
2848.
The identification of Elongated Uppermost Internode (Eui) as a gibberellins (GAs) catabolism gene provides additional evidence that the GA metabolism pathway is a useful target for increasing the agronomic value of crops (Mus musculus) PubMed
2849.
Phylogenetic analysis, supported by comparative mapping in rice and maize (Zea mays), showed that Rc, a positive regulator of proanthocyanidin, is orthologous with INTENSIFIER1, a negative regulator of anthocyanin production in maize. (Mus musculus) PubMed
2850.
GID1 functions as a GA receptor. [GID1] [GIBBERELLIN INSENSITIVE DWARF1] (Mus musculus) PubMed
2851.
PLASTOCHRON2 acts to retard the rate of leaf maturation and is revealed to be an orthologue of terminal ear1, a maize (Zea mays) gene that encodes a MEI2-like RNA binding protein. (Mus musculus) PubMed
2852.
fine-mapping the eui1 gene and identification of its candidate gene using in silico analysis based on previous research work and rice genomic sequence data [EUI1] (Mus musculus) PubMed
2853.
OsDR8 has a role in disease resistance and thiamine accumulation [DR8] (Mus musculus) PubMed
2854.
Xa5 potentially retain their basic transcription factor function, which, in turn, may mediate the novel pathway for bacterial blight resistance and susceptibility, respectively.[xa5] (Mus musculus) PubMed
2855.
RNase-related protein is preferentially expressed in stems of wild-type rice and is significantly down-regulated in an increased tillering dwarf mutant ext37 [RNase-related protein] (Mus musculus) PubMed
2856.
Results describe the DNA renaturation and strand exchange activities of OsDmc1 in real time, using fluorescence resonance energy transfer (FRET) [Dmc1]. (Mus musculus) PubMed
2857.
OsRacB is only an accessory factor in plant salt tolerance [OsRacB] (Mus musculus) PubMed
2858.
OsCRY1 is implicated in blue-light inhibition of coleoptile and leaf elongation during early seedling development in rice, and that the signaling mechanism of OsCRY1 involves direct interaction with OsCOP1 [CRY1b] (Mus musculus) PubMed
2859.
The funtional characterization of MDP1 in O. sativa, including the effects of brassinolide on its expression and regualtion, is presented.[MDP1] (Mus musculus) PubMed
2860.
Pi35(t) is associated with resistance to leaf blast. [Pi35(t)] (Mus musculus) PubMed
2861.
Involved in cell division and might play diverse roles in differentation of panicles. (OsGASR1 and 2 = Oryza sativa GA-stimulated transcript-related gene 1 and 2) (Mus musculus) PubMed
2862.
GER1 expression is induced by early light and jasmonate and its reponse to red light is controlled by phytochrome A and phytochrome B. [GER1] (Mus musculus) PubMed
2863.
results substantiated our contention that OsPT6:1 encoded a high-affinity phosphate transporter of Oryza sativa (Mus musculus) PubMed
2864.
According to high-sequence conservation, the rolled-leaf gene in rice could be orthologous to the Arabidopsis ZIP/Ago7 gene, named OsAGO7. [AGO7 proein] (Mus musculus) PubMed
2865.
The transgenic plants over-expressing OCPI1 had significantly higher grain yield and seed setting rate than the wild type and under the severe drought stress conditions.[OCPI1 protein] (Mus musculus) PubMed
2866.
confirmed that NPR1 is the rice orthologue of Arabidopsis NPR1 by complementing the Arabidopsis npr1 mutant; over-expression of NPR1 conferred disease resistance to bacterial blight, but also enhanced herbivore susceptibility in transgenic plants [NPR1] (Mus musculus) PubMed
2867.
A mutation within the ALS gene confers highly specific resistance to pyrimidinyl carboxy (PC) herbicides. (Mus musculus) PubMed
2868.
1) WOX3 acts as a transcriptional repressor of YAB3. [WOX3] 2) WOX3 acts as a transcriptional repressor of YAB3. [YAB3] (Mus musculus) PubMed
2869.
DNA polymerase may be involved in a repair pathway similar to long-patch base excision repair. (Mus musculus) PubMed
2870.
The rice (E)-beta-caryophyllene synthase (OsTPS3), an enzyme catalyzing the formation of volatile sesquiterpenes, plays a role in indirect defense of rice plants. (Mus musculus) PubMed
2871.
The solution structure of OsCnfU-1A domain I (73-153). (Mus musculus) PubMed
2872.
CONSTITUTIVELY WILTED1-mediated indole-3-acetic acid biosynthesis plays an important role in maintaining root to shoot ratios and, in turn, affects water homeostasis in rice[ CONSTITUTIVELY WILTED1] (Mus musculus) PubMed
2873.
data suggest that OSH6 insertional mutant interferes with a developmental mechanism involved in bract differentiation, especially at the basal nodes of panicles [OSH6] (Mus musculus) PubMed
2874.
In conclusion, the production of incorrect CMO transcripts results in a deficiency of the full-length choline monooxygenase protein and probably reduces glycine betaine accumulation considerably in rice plants. (Mus musculus) PubMed
2875.
The tissues of rice seedlings grown in the presence of tryptamine exhibited a dose-dependent increase in serotonin in parallel with enhanced T5H enzyme activity. (T5H) (Mus musculus) PubMed
2876.
Report of a novel male sterility gene, ms91(t), in a spontaneous mutant line (ms91(t). (Mus musculus) PubMed
2877.
14-3-3 protein may play an important role in regulating ACS activity.(14-3-3) (Mus musculus) PubMed
2878.
OsWRKY89 plays an important role in response to biotic and abiotic stresses. [WRKY89] (Mus musculus) PubMed
2879.
Abscisic acid modulates post-transcriptional gene silencing through the transcriptional control of the OsRDR6 gene (OsRDR6). (Mus musculus) PubMed
2880.
a slight increase in Eui expression could dramatically change rice morphology, indicating the practical application of the Eui gene in rice molecular breeding for a high yield potential. (Mus musculus) PubMed
2881.
SNAC2 is a novel stress responsive NAC transcription factor that possesses potential utility in improving stress tolerance of rice. (Mus musculus) PubMed
2882.
identification of a mutant gene that causes a significant decrease in the width of the leaf blade, termed narrow leaf 7 (nal7); results indicate that NAL7 is involved in auxin biosynthesis and controls leaf shape [NAL7] (Mus musculus) PubMed
2883.
5'-UTR of the rice alcohol dehydrogenase gene contributes to efficient translation in not only dicotyledonous plant cells, but also in monocotyledonous rice cells .(Alcohol Dehydrogenase) (Mus musculus) PubMed
2884.
Complementation tests showed that rice OsMADS22 and OsMADS47 are unable to reverse the flowering-time phenotypes of the svp and agl24 mutants in Arabidopsis. [MADS22, MADS47] (Mus musculus) PubMed
2885.
characterisation of the frg gene in the Azucena variety, one of the few aromatic japonica cultivars [frg] (Mus musculus) PubMed
2886.
OsRecQ1 is a homolog of Neurospora crassa QDE-3, and is required for RNA silencing for inverted repeat DNA, but not for dsRNA. [OsRecQ1] (Mus musculus) PubMed
2887.
LPA1 is involved in phytic acid metabolism in rice. (Mus musculus) PubMed
2888.
results suggested that ZFP177 might play crucial but differential roles in plant responses to various abiotic stresses. (Mus musculus) PubMed
2889.
IPD3 represents a novel gene required for root symbiosis with arbuscular mycorrhizal fungi in plants [IPD3] (Mus musculus) PubMed
2890.
Activation of Ehd1 by OsId1 is required for the promotion of flowering. [Ehd1; OsId1] (Mus musculus) PubMed
2891.
GluD-1 is maximally expressed in the starchy endosperm starting at 5 d after flowering. [GluD-1] (Mus musculus) PubMed
2892.
OsRpl6-1 and OsRpl6-2 have an intron in the 5'-untranslated region, suggesting a gene duplication after its transfer to the nucleus. [Rpl6-2] (Mus musculus) PubMed
2893.
PHR1 is a polyphenol oxidase that contributes to grain discoloration during storage. [PHR1] (Mus musculus) PubMed
2894.
Results indicated that FLEXIBLE CULM1 (FC1), encoding a cinnamyl-alcohol dehydrogenase, plays an important role in the biosynthesis of lignin and the control of culm strength in rice: [FC1] (Mus musculus) PubMed
2895.
NL1 is an intrinsic factor that modulates and coordinates organogenesis through regulating the expression of PLA1 and other regulatory genes during reproductive development in rice. (Mus musculus) PubMed
2896.
2 low phytic acid lines, Os-lpa-XS110-2 & Os-lpa-XS110-3 were identified to carry 2 allelic mutations of rice orthologue, OsMRP5, of maize Lpa1 gene; evidence indicates that the OsMRP5 gene plays an important role in PA metabolism in rice seeds [MRP5] (Mus musculus) PubMed
2897.
The rice SDS and RCK are expressed in young flowers, and transgenic rice lines with reduced expression of these genes exhibited normal vegetative development, but showed reduced fertility with partially sterile flowers and defective pollens. (Mus musculus) PubMed
2898.
The cloning, structure, and characterization of 3BGlu6, a beta-glucosidease, in Oryza satival is reported.[3BGlu6] (Mus musculus) PubMed
2899.
clone and characterize DST, a previously unknown zinc finger transcription factor that negatively regulates stomatal closure by direct modulation of genes related to H(2)O(2) homeostasis [DST (drought and salt tolerance)] (Mus musculus) PubMed
2900.
Missense mutation in OsCESA4 (G858R), a highly conserved residue at the end of the fifth transmembrane domain, results in growth retardation and dramatically reduced plant strength. [CESA4] (Mus musculus) PubMed
2901.
We identified the N15 antirepressor gene, antC, and showed that its product binds to and acts against the main phage repressor, CB.[AntC] (Mus musculus) PubMed
2902.
P1 is required for systemic spread of virus; in Sf9 cells P1 localizes in the fraction of membranes and inclusions but not in soluble cytoplasmic protein fraction [P1 protein] (Mus musculus) PubMed
2903.
Partial proteolysis revealed that the DNA-binding domain of LEF-3 is located within a central region (residues 28 to 326) that is relatively resistant to proteolysis.[Lef-3] (Mus musculus) PubMed
2904.
Our results demonstrate that ac18 is not essential for viral propagation both in vitro and in vivo, but it may play a role in efficient virus infection in T. ni larvae. [ac18] (Mus musculus) PubMed
2905.
We concluded that the gene products encoded from these Ac 101, Ac 142, or the Ac 144 open reading frames are essential for virus production and may be involved in DNA processing, packaging, or nucleocapsid morphogenesis. [Ac 101, Ac 142, Ac 144] (Mus musculus) PubMed
2906.
These results suggest that ac66 plays an important role for the efficient exit of nucleocapsids from the nucleus to the cytoplasm for budded virus synthesis as well as for preoccluded virion and occlusion synthesis.[ac66] (Mus musculus) PubMed
2907.
Induction of apoptosis and budding virus formation occurs in AcMNPV FP-25/p35 double mutant infected Trichoplusia ni cells. [FP-25] (Mus musculus) PubMed
2908.
Domain mapping results showed that all the six domains were required but deletion of the N-terminal acidic region and the leucine zipper domains had the greatest impact on BV production.[Exon0] (Mus musculus) PubMed
2909.
integrity of the ac142-ac143 core gene cluster was required for the bacmids to display wild-type patterns of viral replication, BV production and RNA transcription.[ac142, ac143] (Mus musculus) PubMed
2910.
38K is a novel nucleocapsid protein and provide a rationale for why 38K is essential for nucleocapsid assembly [nucleocapsid protein ] (Mus musculus) PubMed
2911.
a functional nuclear localization domain on LEF-3 was required for interaction between LEF-3 and P143. [LEF-3] (Mus musculus) PubMed
2912.
P35, a caspase inhibitor, is required for robust virion production in Trichoplusia cells. [P35] (Mus musculus) PubMed
2913.
The core protein AC109 is essential for AcMNPV to be able to mount a successful infection. [ac109] (Mus musculus) PubMed
2914.
molecular cloning of a ubiquitin homologue in Spodoptera litura nucleopolyhedrovirus [ubiquitin] (Mus musculus) PubMed
2915.
These results suggest that moricin is present not only in Bombyx mori but also in other lepidopteran insects forming a gene family. (Mus musculus) PubMed
2916.
results suggest that identified SpltNPV-I ORF codes for a serine/threonine kinase. [pk1] (Mus musculus) PubMed
2917.
Splt-iap4 has no antiapoptotic function during SpltNPV infection. (Mus musculus) PubMed
2918.
F protein proved to be a functional analogue of GP64, is present as an oligomer, and possess N-inked glycans [F protein] (Mus musculus) PubMed
2919.
results indicate that the F protein is essential for baculovirus budded virus (BV) infectivity and that the cytoplasmic tail domain is important for F protein incorporation into BV [F protein] (Mus musculus) PubMed
2920.
These results indicate that N-linked glycosylation of the HearNPV baculovirus F(2) subunit is not essential for viral infectivity and suggest that it is involved in BV production and fusogenicity. [F protein] (Mus musculus) PubMed
2921.
These results demonstrate that group II NPV F proteins can be functionally replaced with a homologue of other group II NPVs, suggesting that the interaction of F with other viral or host proteins is not absolutely species-specific. [F protein] (Mus musculus) PubMed
2922.
The putative ACE from the phytopathogenic bacterium, Xanthomonas axonopodis pv. citri, named XcACE was cloned and characterized.(Angiotensin-converting enzyme) (Mus musculus) PubMed
2923.
(Maltose-binding protein; MalE) Study of the crystal structure and organization of MalE will shed light on the mechanism of sugar transport in Xanthomonas species as well as in other phytopathogenic bacteria. (Mus musculus) PubMed
2924.
The cloning, expression, purification and crystallization of PilZ(XAC1133), a protein consisting of a single PilZ domain from Xanthomonas axonopodis pv. citri, is reported.[PilZ] (Mus musculus) PubMed
2925.
The glycoprotein E2, classical swine fever virus expressed in C. reinhardtii chloroplasts could elicit animal bodies to produce antibodies against protein E2. (Mus musculus) PubMed
2926.
proteasomal degradation of interferon regulatory factor 3 is induced by a direct or indirect interaction with N(pro)[Npro] (Mus musculus) PubMed
2927.
Mutations in the carboxyl terminal region of E2 are responsible for viral attenuation. (E2 glycoprotein) (Mus musculus) PubMed
2928.
Expression of NS2-3 and NS4A in trans restored the production of infectious particles from genomes lacking NS2-3 expression and indicate that NS2-3 and NS3, each in association with NS4A, have independent functions in the CSFV life cycle.[NS2-3, NS4A] (Mus musculus) PubMed
2929.
AngM is a nonribosomal peptide synthetase (with peptidyl carrier protein and condensation domains) essential in the biosynthesis of anguibactin. [AngM] (Mus musculus) PubMed
2930.
EmpA is secreted as a approximately 48-kDa proenzyme and that activation occurs extracellularly by the removal of a approximately 10-kDa peptide. [EmpA] (Mus musculus) PubMed
2931.
Four nucleotide sequences showing homology to known hemolysin genes were cloned and sequenced from V. anguillarum strain H775 and demonstrated hemolytic acitivites against fish, sheep, rabbit erythrocytes [Vah2, VAh3, Vah4, Vah5] (Mus musculus) PubMed
2932.
These data show that Epp is the EmpA-processing protease.[Epp in strain M93S] (Mus musculus) PubMed
2933.
receptor-binding protein head domain structure from Lactococcus lactis phage bIL170 [receptor-binding protein] (Mus musculus) PubMed
2934.
sNiV-G binds to ephrinB3 with a 30-fold higher affinity than that of sHeV-G.(sHeV-G) (Mus musculus) PubMed
2935.
the crystal structure of the Yokose virus methyltransferase at 1.7A resolution was presented. (methyltransferase) (Mus musculus) PubMed
2936.
[genome-linked viral protein, VPg] The VPg sequence determined was found to be triplicated in the nonstructural protein precursor. Multiple VPg-like sequences were also found in 10 of the 12 dicistroviruses examined. (Mus musculus) PubMed
2937.
crystal structure of 2C-methyl-D-erythritol-2,4-cyclophosphate synthase [2C-methyl-D-erythritol-2,4-cyclophosphate synthase] (Mus musculus) PubMed
2938.
Results describe the genetic organization of the hrp gene cluster in Erwinia pyrifoliae and characterize HR active domains in HrpNEp protein by mutational analysis [HrpN]. (Mus musculus) PubMed
2939.
rstC gene of vibriophage fs2 integrates into the intergenic region 1 of chromosome 1 of V. cholerae O1 and O139. [rstC] (Mus musculus) PubMed
2940.
The Orf135 protein may be involved in suppressing mutations induced by oxidized deoxynucleotides (Orf135 protein). (Mus musculus) PubMed
2941.
structure of EcAIII, the isoaspartyl peptidase with L-asparaginase activity from Escherichia coli (Mus musculus) PubMed
2942.
nmr assignment of the 23 kDa organomercurial lyase MerB in its free and mercury-bound forms [MerB] (Mus musculus) PubMed
x-ray crystallographic studies of the Afa/Dr adhesin DraE and its interaction with chloramphenicol (Mus musculus) PubMed
2945.
dats show that the host intermediate filament protein cytokeratin 18 (CK18) is an interacting partner of EspF during enteropathogenic Escherichia coli (EPEC) pathogenesis [EspF] (Mus musculus) PubMed
2946.
blue light-regulated phosphodiesterase plays a protective role in response to oxidative stress [blue light-regulated phosphodiesterase] (Mus musculus) PubMed
2947.
role in initiating the mitochondrial death pathway. [EspF] (Mus musculus) PubMed
iucA is associated with virulence in avian pathogenic Escherichia coli (APEC) after exposure by the natural route of infection.[iucA] (Mus musculus) PubMed
2950.
E. coli K1 invasion occurs through the CNF1-67-kDa laminin receptor interaction [CNF1] (Mus musculus) PubMed
2951.
colicin A release was studied and the role played by Cal during secretion was investigated [Cal] (Mus musculus) PubMed
2952.
Hsp31 has roles as both chaperone and peptidase [Hsp31, also called hchA] (Mus musculus) PubMed
2953.
To estimate the prevalence of Shiga toxin producing Escherichia coli in Australia, bloody stool samples from two Australian locations were screened for the presence of Shiga toxin genes, stx1 and stx2. [stx1, stx2] (Mus musculus) PubMed
2954.
expression regulated by lrp as influenced by alanine and leucine [F165 1] (Mus musculus) PubMed
2955.
structural model for NDH-2 through comparative modelling onto a template from this family [NDH-2] (Mus musculus) PubMed
2956.
Crystallographic analysis of the heterodimeric CesA-EspA complex at a resolution of 2.8 A reveals that EspA contains two long a-helices, which are involved in extensive coiled-coil interactions with CesA [CesA & EspA] (Mus musculus) PubMed
2957.
EPEC PerC can activate both the EPEC and EHEC LEE1 promoters and the major transcriptional start site is similarly located in both organisms [PerC] (Mus musculus) PubMed
2958.
analysis of morphinone reductase reaction with 2-cyclohexen-1-one and 1-nitrocyclohexene [morB] (Mus musculus) PubMed
2959.
monomers of HlyB can interact at least transiently and are the important species during ATP hydrolysis [HlyB] (Mus musculus) PubMed
2960.
the two homologous halves of the ArsA may be functionally nonequivalent [ArsA] (Mus musculus) PubMed
2961.
LT(K63/R72) exhibits characteristics more closely related to LT(K63) than LT(R72)[heat-labile enterotoxin LT] (Mus musculus) PubMed
2962.
HosA is involved in temperature-dependent control of swimming motility and cellular aggretation [HosA] (Mus musculus) PubMed
2963.
findings show that EscJ comprises two subdomains (D1 - amino acid residues 1-55 in the mature protein, and D2 - amino acid residues 90-170), each comprising a three-stranded beta-sheet flanked by two alpha-helices (Mus musculus) PubMed
2964.
Pro-sequence and Ca2+-binding of Ntn-hydrolase penicillin amidase [pro-PA] (Mus musculus) PubMed
2965.
A new variant of the E. coli intimin protein (eae) is reported in cattle.[eae] (Mus musculus) PubMed
2966.
The peripheral stalk of F(1)F(0) ATP synthase is composed of a parallel homodimer of b subunits that extends across the cytoplasmic membrane. (f1f0-atp synthase) (Mus musculus) PubMed
2967.
with TrwB structural similarity to F1-ATPase, a mechanism for TrwB as a DNA-translocating motor is proposed [TrwB] (Mus musculus) PubMed
2968.
We have expressed the full-length and half domains of bovine bone sialoprotein in a prokaryotic system and identified the phosphorylation sites of casein kinase II. [casein kinase II] (Mus musculus) PubMed
2969.
in GRP94, ATP binding dictates the conformation of the N-domain and regulates its ability to form quaternary structural interactions [GRP94] (Mus musculus) PubMed
2970.
in extraintestinal Escherichi coli infections, no HylaA+ sheA+ strains were identified, suggesting possible incompatibility between HlyA and SheA in the chromosome of E. coli [HlyA] (Mus musculus) PubMed
2971.
QnrA binds to topoisomerase IV and its subunits in a reaction that does not depend on the presence of DNA, quinolone, or ATP [QnrA, quinolone resistance protein] (Mus musculus) PubMed
2972.
Arg-70 influences catalysis in HpaI at the pyruvate proton exchange step; highest activity for HpaI is found with Co2+ and Mn2+ as the cofactor. (HpaI; multifunctional; pyruvate-specific class II aldolase) (Mus musculus) PubMed
2973.
The nucleotide-binding domain of the HlyB transporter is characterized with respect to its uncoupled ATPase activity, oligomeric state, and stability in solution. (HlyB) (Mus musculus) PubMed
2974.
The alkyltransferase-like (ATL) protein inhibited the transfer of methyl groups to O6-methylguanine-DNA methyltransferase (ATL). (Mus musculus) PubMed
2975.
The SXN motif of PBP 5, and especially Ser110, is intimately involved in the catalytic mechanism of deacylation. (Mus musculus) PubMed
2976.
structures of the wild-type and the S70G TEM-1 beta-lactamase determined to 1.55 and 2.1 A, respectively, are presented [TEM-1 beta-lactamase] (Mus musculus) PubMed
2977.
new insights on the structural properties and temperature stability of the calcium depleted D-galactose/D-glucose-binding protein (GGBP) contribute to better understanding of the protein function [D-galactose/D-glucose-binding protein] (Mus musculus) PubMed
2978.
both a large cell-surface protein designated Contact-dependent inhibitor A (CdiA) and two-partner secretion family member CdiB were required for contact-dependent growth inhibition [CdiA, CdiB] (Mus musculus) PubMed
2979.
This result demonstrates an essential role for Ler in in vivo pathogenicity of attaching/effacing (A/E) E. coli. (Mus musculus) PubMed
2980.
Modulation of polymorphonuclear leukocyte (PMN) function by CNF1 facilitates uropathogenic Escherichia coli (UPEC)survival during the acute inflammatory response [cytotoxic necrotizing factor type 1; CNF1] (Mus musculus) PubMed
2981.
hydrophilic domain II of the structural fimbrial subunit DraE may be involved in cell entry (DraE) (Mus musculus) PubMed
2982.
Opening and closing of the catalytic chain domains of aspartate transcarbamoylase explains how the catalytic cycle occurs while the enzyme remains globally in the R-quaternary structure. (Mus musculus) PubMed
2983.
study showed that the lpfA genes identified in the genome of shiga toxin-producing Escherichia coli (STEC) strains are not specific to this category; results suggest that there is a relationship between the lpfA variant and the phylogenetic group [lpfA] (Mus musculus) PubMed
2984.
a molecular chaperone involved in recruiting multiple type III effectors to the T3SS via EscN for efficient secretion [CesT] (Mus musculus) PubMed
2985.
Data describe the post-transcriptional regulation of the biosynthesis of the periplasmic protein, penicillin amidase [penicillin amidase] (Mus musculus) PubMed
2986.
type-I methionyl aminopeptidases (MetAPs) can be selectively targeted over type-II MetAPs [type-I MetAPs and type-II MetAPs] (Mus musculus) PubMed
EspB protein (312 residues in total) has functions associated with its different regions. These regions may interact with each other or with other components of the type III system to orchestrate the intricate actions of EHEC during infection. [EspB] (Mus musculus) PubMed
2989.
molecular characterization of the organomercurial lyase merB gene from the different wild broad-spectrum E. coli isolates from the Indian subcontinent [merB] (Mus musculus) PubMed
2990.
crystal structures of ecLeuRS-ED (the editing domain of Escherichia coli LeuRS) in both the apo form and in complexes with Met and Ile at 2.0 A, 2.4 A, and 3.2 A resolution respectively.[leucyl-trna synthase] (Mus musculus) PubMed
2991.
AAA+ ATPases are ubiquitous proteins that employ the energy obtained from ATP hydrolysis to remodel proteins, DNA, or RNA. (AAA+ atpase) (Mus musculus) PubMed
2992.
description of DHA-1 cephalosporinase production in E. coli [DHA-1] (Mus musculus) PubMed
2993.
fraction of alpha-haemolysin is located within outer membrane vesicles that are released by the bacteria; propose an alternative pathway for the transport of alpha-haemolysin from the bacteria to host cells during bacterial infections [alpha-haemolysin] (Mus musculus) PubMed
2994.
There is a direct functional role for the 14-3-3tau:Tir interaction in E.coli infection. (Mus musculus) PubMed
2995.
K-API is now the second Kdo biosynthetic related gene that has been characterized from the kps group 2 capsule cluster [kpsF] (Mus musculus) PubMed
2996.
evolutionarily related family of aldolases distinct from the N-acetylneuraminate lyase (NAL) family [2-keto-3-deoxy-6-phosphogluconate aldolase] (Mus musculus) PubMed
2997.
analysis of hydrolysis of ATP by aminoglycoside 3'-phosphotransferase [APH3'Ia] (Mus musculus) PubMed
2998.
The KpsD protein, previously believed to be a periplasmic protein, is an outer membrane protein involved in the export of group 2 capsular polysaccharides across the outer membrane. (Mus musculus) PubMed
2999.
random mutagenesis studies suggest that EspB has distinct domain functions involved in effector translocation that can be distinguished from its role as a component of the translocation pore. [EspB] (Mus musculus) PubMed
3000.
the ArsA ATPase Cys-113 and Cys-422 form a high affinity metalloid binding site [ArsA] (Mus musculus) PubMed
3001.
results showed that three nonpolar amino acids at positions 381-383 (Phe-Leu-Leu) of AatA were required for export of dispersin, and these residues were located at the base of carboxy-terminal elongation in the equatorial domain of AatA [AatA, dispersin] (Mus musculus) PubMed
crystallization of cytolethal distending toxin (CdtB); CdtB crystals contain one molecule of MW 30.5 kDa per asymmetric unit, belong to space group P2(1)2(1)2(1) and diffract to 1.72 A [CdtB] (Mus musculus) PubMed
3004.
solved the crystal structure of the N-terminal relaxase domain of TrwC in complex with a 27 base-long DNA oligonucleotide that contains both the recognition hairpin and the scissile phosphate (Mus musculus) PubMed
3005.
The role of the CvaB protein c-terminal domain in the synthesis of colicin V in E. coli is reported.[CvaB] (Mus musculus) PubMed
3006.
The role of polyamines in the expression and effects of ColE7 in E. coli are reported.[ColE7] (Mus musculus) PubMed
3007.
Two-partner secretion locus etpBAC directs secretion of a high-molecular-weight glycosylated protein, EtpA, that in concert with the putative EtpB transporter participates in adherence of enterotoxigenic strain H10497 to epithelial cells. (EtpA, EtpB) (Mus musculus) PubMed
3008.
results indicate that EscC, EscD, and EscJ are required for the formation of the TTS (Type III Secretion) apparatus [EscC, EscD, EscJ] (Mus musculus) PubMed
3009.
identified sorting nexin 9 (SNX9) as a host cell EspF binding partner protein, which binds EspF via its amino-terminal SH3 region [EspF] (Mus musculus) PubMed
3010.
transcription control by Fit factors in vivo are discussed [fitA, fitB & fitC4] (Mus musculus) PubMed
3011.
The mechanisms underlying the Ca2+ oscillations induced by alpha-hemolysin are reported.[HlyA] (Mus musculus) PubMed
3012.
tRNase Z cleaves several unstructured RNAs other than pre-tRNAs, with a tendency to cleave after cytidine or before uridine [tRNase Z] (Mus musculus) PubMed
3013.
EspF-mediated inhibition of PI-3 kinase-dependent uptake: (i) is independent of mitochondrial targeting, (ii) requires the N-terminal domain and (iii) the C-terminal domain is sufficient to disrupt barrier function but not inhibition of bacterial uptake. (Mus musculus) PubMed
3014.
The mechanism of tetracycline resistance was studied using expression studies in E. coli mutants that were defective in the tet(A) and the tolC proteins.[tet9A)] (Mus musculus) PubMed
3015.
Study indicates that M.EcoHK31I is composed of polypeptides alpha and beta. The N-terminal region of polypeptide beta takes part in subunit interaction, while the C-terminal region is involved in DNA binding [M.EcoHK31I ] (Mus musculus) PubMed
3016.
evidence for chromosomal location of blaVIM-2 & blaGES-7 genes carried by a clinical isolate; the blaVIM-2 gene has been found on a class I integron, designated In8 [blaVIM-2, blaGES-7] (Mus musculus) PubMed
3017.
mutagenesis and crystallographic studies of DaaE; Naturally occurring variants and directed mutations in DaaE have been generated and analyzed for their ability to bind DAF(DaaE) (Mus musculus) PubMed
3018.
EilA contributes to virulence and activates the genetically linked high molecular weight bacterial surface protein Air [EILA] (Mus musculus) PubMed
3019.
Mutagenesis and chemical rescue data implicate the C-proximal Arg320, Glu324 and, possibly, His356 in catalysis by PrrC-anticodon nuclease (PrrC). (Mus musculus) PubMed
3020.
HbiF-mediated OFF-to-ON fimS molecular switching is independent of FimB and FimE. (HbiF) (Mus musculus) PubMed
3021.
(p)ppGpp regulates transcription of fimB promoter. (Mus musculus) PubMed
3022.
X-ray structure of the CdtB subunit (Escherichia coli-II CdtB, EcCdt) (Mus musculus) PubMed
3023.
we examine stability & folding/unfolding kinetics of Lpp-56 at neutral pH using GdmCl as denaturant. Folding & unfolding appear to represent structural transitions between folded trimer & unfolded monomer, without detectable intermediates[Lpp-56] (Mus musculus) PubMed
3024.
The catalytic cycle of isolated ATP-binding cassette (ABC)-transporter-nucleotide-binding domains of HlyB is divided into distinct steps that involve different conserved sequence motifs as key players, acting to coordinate intramolecular movements. (Mus musculus) PubMed
3025.
OMVs provide a means for delivery of cytotoxic necrotizing factor type 1 (CNF1) from a UPEC strain to PMNs and thus negatively affect the efficacy of the acute inflammatory response to these organisms. [CNF1] (Mus musculus) PubMed
3026.
aldose sugar dehydrogenase from Escherichia coli has a highly exposed active site conferring broad substrate specificity [Asd] (Mus musculus) PubMed
3027.
The induction of MdtEF expression in E. coli by multiple compounds, including GlcNAc, is presented. (Mus musculus) PubMed
3028.
High level expression of full length and truncated myocilins in E. coli. Bacterial and eukaryotic recombinant full length myocilin produced similar biological effect on trabecular meshwork cells. Phenotype largely due to the NH(2)-terminal half. (Mus musculus) PubMed
3029.
Study provides evidence that the secreted autotransporter toxin, Sat, acts as a virulence factor in Afa/Dr diffusely adhering Escherichia coli (DAEC) by promoting lesions in tight junctions of polarized epithelial Caco-2 cells [Sat] (Mus musculus) PubMed
3030.
analysis of the structure of R- and T-state Escherichia coli aspartokinase III (Mus musculus) PubMed
3031.
influence of the ung, dug, and dut genes in preventing uracil residues from accumulating in E. coli DNA was quantitatively determined [double-strand uracil-DNA glycosylase (dug)] (Mus musculus) PubMed
3032.
The first structural characterization of gentisate 1,2-dioygenase from the pathogenic O157:H7 Escherichia coli strain was reported. (Mus musculus) PubMed
3033.
Secreted autotransporter toxin, a serine protease, enters human bladder and kidney epithelial cells and localizes specifically to the cytoskeletal fraction where proposed protein targets reside. (secreted aurotransporter toxin) (Mus musculus) PubMed
3034.
GpUp is the minimal substrate strictly retaining specificity for ribonuclease activity by the Colicin E5 C-terminal domain (Colicin E5). (Mus musculus) PubMed
3035.
Two new crystal structures (free enzyme and enzyme-substrate complex), NMR, and site-directed mutagenesis data, suggest a four-stage catalytic cycle for the enzyme GDP-mannose mannosyl hydrolase. [Yefc protein] (Mus musculus) PubMed
3036.
These results show that diffuse positive charge associated with the C-terminal subdomains of EcoRV plays a key role in DNA association, bending, and cleavage.[EcoRV] (Mus musculus) PubMed
3037.
The reaction of glutamate mutase with the glutamate analogue, 2-thiolglutarate, was analysed. (Mus musculus) PubMed
3038.
OmpA facilitates the interaction of E. coli with human brain microvascular endothelial cells. (Mus musculus) PubMed
3039.
EibG acts as an IgG Fc- and IgA-binding protein, as well as an adhesin of LEE-negative Shiga toxin-producing Escherichia coli.(EibG) (Mus musculus) PubMed
3040.
Homotropic cooperative interactions between the catalytic sites for the binding of aspartate are explained by a quaternary structure transition from T state (aspartate low affinity) to R state (aspartate high affinity). (Mus musculus) PubMed
3041.
observations suggest that dissociation of the colicin E2 immunity protein occurs at the outer membrane surface and requires full translocation of the colicin E2 N-terminal domain [colicin E2 immunity protein] (Mus musculus) PubMed
3042.
Study shows that relaxase TrwC promotes recombination between two directly repeated oriTs while related relaxases TraI of F and pKM101 do not. [TrwC protein] (Mus musculus) PubMed
3043.
heat-labile enterotoxin B subunit pentamer (EtxB5) assembly in vitro is inhibited using monoclonal antibodies (Mus musculus) PubMed
3044.
experiments suggest that the proteolytic processing of AIDA-I plays a minor role in the functionality of this protein in adhesion. [AIDA-I] (Mus musculus) PubMed
3045.
NMR studies suggest that dilution of the chaotrope to initiate refolding will result in collapse of the clusters, leading to the formation of persistent helical structure and the three-helix folding intermediate.(colicin immunity protein Im7) (Mus musculus) PubMed
3046.
The nascent RNA-mediated destabilization of an interaction between sigma(70) region 4 and the flap domain of the beta subunit is required for the bacteriophage lambda Q antiterminator protein to contact holoenzyme during early elongation. (Mus musculus) PubMed
3047.
The results of these experiments show that while the target size of the catalytic activity for K92 polysialyltransferase is larger than a monomer of NeuS, a large complex is not required for catalysis.[NeuS polysialyltransferase] (Mus musculus) PubMed
3048.
Crystal structures of colicin E5-C-terminal domain complexed with its substrate analog and ImmE5 clearly demonstrate the mechanism by which specific substrate recognition is achieved (colicin E5). (Mus musculus) PubMed
3049.
structure of Escherichia coli PapI, a key regulator of the pap pili phase variation [PapI] (Mus musculus) PubMed
3050.
Ser503 and Gln504 in aromatic stacking region of CvaB block the ATP binding and are important for the GTP-binding preference[CvaB] (Mus musculus) PubMed
3051.
Reconstruction of an N-terminal truncate rendered FedF amenable to crystallization, resulting in crystals with space group P2(1)2(1)2(1) and unit-cell parameters a = 36.20, b = 74.64, c = 99.03 A that diffracted to beyond 2 A resolution[FedF] (Mus musculus) PubMed
3052.
Overall activities of the purified GmrSD enzyme are in good agreement with the properties of the cloned gmr genes in vivo and suggest a restriction enzyme specific for sugar modified hydroxymethylcytosine DNAs.[GmrS, GmrD] (Mus musculus) PubMed
3053.
Stx1 activates both apoptotic and cell survival signaling pathways in human macrophage-like myelogenous leukemia THP-1 cells. (Stx1; Shiga toxin 1) (Mus musculus) PubMed
3054.
When an SSB variant that lacks the C-terminal 8 amino acids is used, the capacity of RecOR to facilitate RecA loading onto the ssDNA is largely abolished[SSB protein] (Mus musculus) PubMed
The PapG II adhesin can enhance the early establishment of E. coli infection in the kidney [PapG II adhesin]. (Mus musculus) PubMed
3057.
This is the first report which documents the cell surface-to-ER and ER-to-cytosol trafficking of a bacterial non-AB toxin, Plasmid-encoded toxin. [Pet] (Mus musculus) PubMed
3058.
Study provides evidence for the molecular basis for the enhanced spontaneous mutator activity of RumA'B as well as explains its ability to promote efficient and accurate bypass of T-T pyrimidine dimers in vivo. [RumA'B protein, Bacteria] (Mus musculus) PubMed
3059.
The dimeric ImE7 protein is involved in a sequence-specific cleavage at the ceiE7 mRNA (ImE7). (Mus musculus) PubMed
3060.
These results demonstrate for the first time that STb can permeabilize its target membrane and suggest that it does so by forming nonspecific pores on piglet jejunal brush border membrane vesicles. (Mus musculus) PubMed
3061.
A proposed model in which transcriptional repression of the parD operon is tuned by the relative molar ratio of the Kid antitoxin and Kis toxin protein (Kid and Kis). (Mus musculus) PubMed
3062.
These results suggest that IbeA interacts with polypyrimidine tract-binding protein (PTB)-associated splicing factor (PSF) for the E. coli K1 invasion of HBMEC.[IbeA] (Mus musculus) PubMed
3063.
the calcium-binding C-terminal domain of Escherichia coli alpha-hemolysin is a major determinant in the surface-active properties of the protein [HlyA] (Mus musculus) PubMed
3064.
We have used phosphorescence spectroscopy to investigate the effects of glucose and calcium on the dynamics and stability of GGBP. (GGBP) (Mus musculus) PubMed
3065.
6S RNA interferes with transcription initiation and also acts as a template for the transcription of defined RNA molecules in the absence of DNA (6S RNA). (Mus musculus) PubMed
3066.
The subcellular targeting of E. coli K99 FanC to chloroplasts of transgenic soybeans is reported.[FanC] (Mus musculus) PubMed
3067.
These studies suggest that QseA activates the transcription of LEE1 by directly binding upstream of its P1 promoter region. [QseA] (Mus musculus) PubMed
3068.
The passenger domain of the Escherichia coli O157:H7 autotransporter EspP is released in a novel autoproteolytic reaction.[EspP] (Mus musculus) PubMed
3069.
TraY and IHF recognize sbyA and ihfA with limited sequence specificity and with relaxosome proteins requiring proper spacing and orientation with respect to each other[traY and IHF] (Mus musculus) PubMed
3070.
UDP-hexose 4-epimerase gene was found & characterized to be able to catalyze interconversion between UDP-GlcNAc/GalNAc and UDP-Glc/Gal with almost equal efficiency Deletion of gne1 in O86:B7 mutant exhibited rough LPS[gne1] (Mus musculus) PubMed
3071.
The aim of this study was to determine if tccP2 is found in atypical EPEC isolated from human and farm animals; tccP2 was found at a frequency of 41% in non-O26 EPEC isolates and in 82.3% of the O26 strains. [tecP2 protein] (Mus musculus) PubMed
3072.
short and long range residue motions could play an important catalytic role in TEM-1 beta-lactamase [TEM-1] (Mus musculus) PubMed
3073.
The cytotoxic necrotizing factors CNF1 and CNF2 of Escherichia coli and CNF(Y) of Yersinia pseudotuberculosis bind to different cellular receptors but are released into the cytosol from acidified endosomes. [CNF1 and CNF2] (Mus musculus) PubMed
3074.
The junction region of the passenger domain in AIDA-I is involed in the biogenesis of AIDA-I by interacting with and/or promoting folding of native passenger domains. [AIDA-I] (Mus musculus) PubMed
3075.
Access to a bona fide wild-type PcoC protein allowed unequivocal observation of intermediates involved in intermolecular redox copper transfer reactions[PcoC] (Mus musculus) PubMed
3076.
Isolates lacking papGII were more frequent among patients with urinary tract abnormalities (58% vs. 10%, p 0.0003), as were non-virulent phylogenetic group A isolates (25% vs. 5%, p 0.043)in E. coli causing pyelonephritis in children. [PapGII] (Mus musculus) PubMed
3077.
Results show that the N-terminal extension of PapF is required to adapt the PapG adhesin to the tip of the fiber [PapF,PapG] (Mus musculus) PubMed
3078.
Studies suggest that CexE may be a novel ETEC virulence factor because its expression is controlled by the virulence regulator CfaD [CfaD and CexE] (Mus musculus) PubMed
3079.
analysis of catalytic residues of the cyclase NisC involved in the biosynthesis of nisin [NisC] (Mus musculus) PubMed
3080.
identification of the VIM-1/VIM-2 hybrid metallo-beta-lactamase VIM-12 gene in a clinical isolate.[VIM-12] (Mus musculus) PubMed
3081.
strains belonging to EPEC 2 can trigger actin polymerization using both Nck and TccP2 actin-polymerization signalling cascades.[TccP2 protein] (Mus musculus) PubMed
3082.
Free methionine-(R)-sulfoxide reductase (fRMsr) is 100- to 1,000-fold more active than non-selenocysteine-containing MsrB enzymes for free Met-(R)-O. [fRMsr] (Mus musculus) PubMed
3083.
The CTX-M-14 ESBL in E. coli isolates is the result of the convergence of two different genes.[CTX-M-14] (Mus musculus) PubMed
3084.
Modelling substrate into the active site suggests the attacking water molecule is not part of the metal coordination shell [HpcG] (Mus musculus) PubMed
3085.
The carboxyl-terminal regions of TraG and Eex were found to localize in the cell cytoplasm; suggesting that complex topological rearrangements of conjugative proteins must occur during mating to enable these domains to interact.[Eex,TraG] (Mus musculus) PubMed
3086.
The 2.5 A crystal structure of the receptor-binding B-subunit of hLT in complex with the blood group A antigen analog provides evidence of a previously unknown binding site in the native toxin.[enterotoxin LT] (Mus musculus) PubMed
3087.
analysis of structural model of the R state of Escherichia coli aspartate transcarbamoylase with substrates bound [aspartate transcarbamoylase] (Mus musculus) PubMed
3088.
Peptide mimicry and Cys-mediated intersubunit cross-linking data suggest that the tRNALys-binding motif of PrrC is shared by C-domain portions interfacing in parallel (PrrC). (Mus musculus) PubMed
3089.
We found that 3'-phosphoadenosine 5'-phosphate phosphatase (CysQ) of Escherichia coli exhibited NADP(H) phosphatase and fructose-1,6-bisphosphatase activities. [CysQ] (Mus musculus) PubMed
3090.
there is strong coupling between cyclic nucleotide binding and MloK1 channel opening [MloK1] (Mus musculus) PubMed
3091.
F1-ATPase of the F(O)F1 ATP synthase complex involves rotation of the central gamma subunit relative to the catalytic sites in the alpha3beta3 pseudo-hexamer. We name this step k(gamma). (Mus musculus) PubMed
3092.
description of facile room-temperature protolytic cleavage by a thiol of the Hg-C bond in mercury-alkyl compounds that emulate the structure and function of the organomercurial lyase MerB [MerB] (Mus musculus) PubMed
3093.
inhibition of conjugative relaxases is a potentially novel antimicrobial approach[DNA relaxase] (Mus musculus) PubMed
3094.
Hygromycin B phosphotransferase (Hph; EC 2.7.1.119) converts hygromycin B to 7''-O-phosphohygromycin using a phosphate moiety from ATP, resulting in the loss of its cell-killing activity. (Mus musculus) PubMed
3095.
ErpA is an A-type Fe-S protein that is characterized by an essential role in cellular metabolism[ErpA] (Mus musculus) PubMed
3096.
CNF1 contains two major binding regions for binding to laminin receptor precursor protein: one located within the N terminus, which contained amino acids 135 to 164, and one which resided in the C terminus and included amino acids 683 to 730. (Mus musculus) PubMed
3097.
cytolethal distending toxin-1Phi is the latest member of a growing family of lambdoid phages encoding bacterial cyclomodulins [cytolethal distending toxin and type III effector protein] (Mus musculus) PubMed
3098.
The results suggest that the excision event in E. coli may involve additional factors, such as RecA and that the physiological status can influence the excision of nifD element.[RecA] (Mus musculus) PubMed
3099.
These data indicate that Pet secreted by EAEC binds to the cell surface via an unknown receptor, to be taken up by clathrin-mediated endocytosis, and exert its toxic effect in the cytoplasm. [Pet] (Mus musculus) PubMed
3100.
The biological function of GlmZ is to positively control the glmS mRNA in response to GlcN-6-P concentrations and that YhbJ negatively regulates GlmZ. As in yhbJ mutants GlcN-6-P has no effect, YhbJ is essential for sensing this metabolite.[GlmZ] (Mus musculus) PubMed
3101.
The steady-state kinetics and ligand binding properties of coaD in the biosynthesis of coenzyme A are reported.[CoA] (Mus musculus) PubMed
3102.
Infection of mice with hph-expressing H. capsulatum yeast cells at sublethal doses resulted in lethality. (Mus musculus) PubMed
3103.
Data show that ParM filaments have subunit-subunit interfaces that result in the helical handedness of the ParM filament being opposite to that of F-actin [ParM]. (Mus musculus) PubMed
3104.
A stem-loop structure on the sblA transcript plays a negative role in the regulation of sblA expression and might be involved in the regulation of the specific degradation of the sblA transcript.[sblA] (Mus musculus) PubMed
3105.
the NaK channel has a a Ca(2+) binding site at the extracellular entrance to the selectivity filter which allows Ca(2+) to act both as a permeating ion and blocker of CNG channels (Mus musculus) PubMed
3106.
Data showed crystal structure of HpcH in the apo form, and with magnesium and the substrate analogue oxamate bound, to 1.6 A and 2.0 A [HpcH] (Mus musculus) PubMed
3107.
analysis of the role of copper in folding and stability of cupredoxin-like copper-carrier protein CopC [CopC] (Mus musculus) PubMed
3108.
We conclude that the Lon protease supports survival during anaerobic carbon starvation by a mechanism which does not depend on Clp.[Lon in strain SG1094] (Mus musculus) PubMed
3109.
These findings suggest that the EspF-dependent assembly of SNX9 and N-WASP represents a novel form of signaling mimicry used to promote Escherichia coli pathogenesis and gastrointestinal disease.[EspF] (Mus musculus) PubMed
3110.
the centromere-like parC DNA is wrapped around a ParR protein scaffold and works with ParM polymerization to drive active DNA transport during plasmid partition [parR, parM] (Mus musculus) PubMed
3111.
The localized adherence pattern of an atypical enteropathogenic Escherichia coli is mediated by intimin encoded by the eae gene. [eae] (Mus musculus) PubMed
3112.
analysis of the structural stability and dynamics of D-galactose/D-glucose-binding protein from Escherichia coli [GGBP] (Mus musculus) PubMed
3113.
quantitative description of KcsA gating and of the macroscopic currents [KcsA] (Mus musculus) PubMed
3114.
kinetic model is proposed to describe the gating events in KcsA that recapitulates its macroscopic and single-channel behavior [KcsA] (Mus musculus) PubMed
3115.
analysis of the membrane-aqueous border for the voltage-sensing domain of potassium channel KvAP [KvAP] (Mus musculus) PubMed
3116.
glycosylation is required to ensure a normal conformation of AIDA-I and may be only indirectly necessary for its cell-binding function.[AidA-I] (Mus musculus) PubMed
3117.
a two-step reaction model mechanism is proposed, in which zinc-binding is regulated by the initial selective-binding of Zn(2+) to Cys followed by folding(Tim10) (Mus musculus) PubMed
3118.
Immunoprecipitation experiments revealed that LeoA interacts directly with OmpA, but that the GTP-binding domain is non-essential for this interaction in ETEC. [LeoA, OmpA] (Mus musculus) PubMed
3119.
phosphorescence of GlnBP is easily detected where emission of 2 tryptophan residues is readily discriminated by drastic difference in phosphorescence lifetime allowing assignments of short lifetime to W220 & long lifetime to W32[glutamine-binding protein] (Mus musculus) PubMed
3120.
EspI modulates the virulence of attaching and effacing pathogens by binding host PDZ-domain proteins. (Mus musculus) PubMed
3121.
This study showed that divergent transcription from a strong promoter can significantly enhance fooB expression and compensate for the absence of FooI in a wild-type strain.[FooB, FooI] (Mus musculus) PubMed
3122.
dispersin's likely role in fimbrial function is to overcome electrostatic attraction between aggregative adherence fimbriae and the bacterial surface.[dispersin in strain ES66] (Mus musculus) PubMed
3123.
Analysis of infrared polarized absorbance spectra and linear dichroism spectra of reconstituted melibiose permease from Escherichia coli [MelB] (Mus musculus) PubMed
3124.
It was found that Tyr4, Trp5, Glu15, Tyr45, Tyr61, and Glu82 in MdtJ and Glu5, Glu19, Asp60, Trp68, and Trp81 in MdtI are involved in the speridine excretion activity of MdtJI. [MdtI] (Mus musculus) PubMed
3125.
Structure discrimination for the C-terminal domain of Escherichia coli trigger factor in solution (Mus musculus) PubMed
3126.
By atomic force microscopy, ParR molecules are shown to bind to each of the 5-fold repeated iterons of the plasmid R1 centromere-like site parC (parR). (Mus musculus) PubMed
3127.
there is only a single high-affinity metalloid binding site in ArsA, and second that Cys-172 controls the affinity of this site for metalloid and hence the efficiency of metalloactivation of the ArsAB efflux pump (Mus musculus) PubMed
3128.
the CpxAR stress response indirectly controls the synthesis of the F mating apparatus, a complex transenvelope type IV secretion system, by degrading TraJ via HslVU. [HslV and HslU] (Mus musculus) PubMed
3129.
An "on-pathway" IM7 intermediate with nonnative interactions is formed as a consequence of an unusual cluster of highly frustrated interactions in the native structure; this cluster is involved in the binding of IM7 to its target, colicin E7. {IM7) (Mus musculus) PubMed
3130.
These results imply that Rnase E plays a dual role in processing and degradation to achieve tight control of M1 RNA biosynthesis.[Rnase E] (Mus musculus) PubMed
3131.
The expression of acid phytase (APPA)in transgenic soybeans and the metabolism of phytate to phosphorus are reported. (Mus musculus) PubMed
3132.
analysis of barriers and barrierless folding in BBL [BBL] (Mus musculus) PubMed
3133.
The contributions of HPF to 100S formation and translation were analysed in vitro.[HPF] (Mus musculus) PubMed
3134.
beta-1,3-galactosyltransferase from E. coli O127 expresses a T-antigen mimic in the lipopolysaccharide (LPS) structure. glycosylates a series of GalNAc analogues with alpha-substitutions at the reducing end, including glycosylated Ser & Thr [WbiP] (Mus musculus) PubMed
3135.
(PET, Escherichia coli) is expressed and shown to exhibit a 3-state folding and have a stable core structure. (Mus musculus) PubMed
3136.
The IncH entry exclusion proteins EexA and EexB likely prevent redundant plasmid transfer by interaction with one another.[EexA, EexB] (Mus musculus) PubMed
3137.
These results suggest that EspJ EspJ(EHEC) in phagocytes is sufficient to inhibit internalization of both IgG- and C3bi-opsonized RBC.[EspJ] (Mus musculus) PubMed
3138.
the ability of S1 to recognize different RNAs results from a high adaptability of both its structure and its binding surface (Mus musculus) PubMed
3139.
the molecular events coupled to ATP binding and hydrolysis (Mus musculus) PubMed
3140.
Residue F180 of lactaldehyde dehydrogenase participates in the exclusion of NADP+ from the coenzyme binding site and disturbs the binding of NAD+ (lactaldehyde dehydrogenase). (Mus musculus) PubMed
3141.
single-stranded DNA-binding protein functions to recruit polV to primer termini on RecA-coated DNA[Single-stranded DNA-binding protein] (Mus musculus) PubMed
3142.
These results demonstrate that PepA requires specific DNA sequences for binding, and that PepA and ArgR have no direct role in Cre recombination at P1 loxP.[PepA, ArgR] (Mus musculus) PubMed
3143.
This study investigated the role of the Cpx response in enteropathogenic Escherichia coli type III secretion through the locus of enterocyte effacement (LEE) pathogenicity island expression.[LEE] (Mus musculus) PubMed
3144.
Gene opgB was reported to encode phosphoglycerol transferase I; in this study, it is demonstrated that the periplasmic phosphoglycerol transferase II is a soluble form of the membrane-bound phosphoglycerol transferase I. (Mus musculus) PubMed
3145.
enzymatic properties of this lytic transglycosylase domain were found to be very similar to those of the wild-type enzyme[YfhD] (Mus musculus) PubMed
3146.
The structure of a new ternary complex (FimC-FimF(t)-FimD(N)) with the subunit FimF(t) instead of FimH(p), is reported.[FimC, FimF, FimD] (Mus musculus) PubMed
3147.
The crystal structure of the DapD tetrahydrodipicolinate N-succinyltransferase from Escherichia coli at 2.0 A resolution, is reported.[THDP N-succinyltransferase] (Mus musculus) PubMed
3148.
AcpT overexpression also suppressed the lethality due to deletion of the entire yejM gene and this suppression also did not require that AcpT be enzymatically active.[AcpT, YejM] (Mus musculus) PubMed
3149.
there is an orientation-dependent impediment to polymerase progression on 5'-CAG and 5'-CTG repeats that can be relieved by the binding of single-stranded DNA-binding protein [ssb] (Mus musculus) PubMed
3150.
these data suggest that EtpA is required for optimal colonization of the intestine, findings paralleling those of previous in vitro studies demonstrating its role in adherence.[EtpA in strain H10407] (Mus musculus) PubMed
3151.
results provide the structural basis for understanding the coupling between protein synthesis and enzymatic processing of nascent chains, and offer insights into the interplay of PDF with the ribosome-associated chaperone trigger factor [def =PDF] (Mus musculus) PubMed
3152.
Thermal denaturation of penicillin acylase (PA) from Escherichia coli has been studied by high-sensitivity differential scanning calorimetry as a function of heating rate, pH and urea concentration.[Penicillin acylase] (Mus musculus) PubMed
3153.
Electrochemistry measurements on DNA-modified electrodes are used to probe the effects of binding to DNA on the redox potential of SoxR, a transcription factor that contains a [2Fe-2S] cluster and is activated through oxidation.[SoxR] (Mus musculus) PubMed
3154.
The role of glycine residues in EmrE, a small multidrug transporter from Escherichia coli, was studied.[EmrE] (Mus musculus) PubMed
3155.
Osmotic induction of cardiolipin (CL) synthesis and concentration of ProP with CL at the cell poles adjust the osmotic activation threshold of ProP to match ambient conditions.[ProP] (Mus musculus) PubMed
3156.
The phenotype of the arcA2 mutants was due to the presence of a creC constitutive mutation introduced by P1 transduction. (creC)(arcA2) (Mus musculus) PubMed
3157.
Mutations in highly conserved residues at the active site affect the activity of the enzyme. Moreover, we have identified the residue that is responsible for setting the end product of RNase II [RNase II] (Mus musculus) PubMed
3158.
secondary structure model of membrane-bound UbiA [UbiA] (Mus musculus) PubMed
3159.
synergistic anion plays a structural and functional role in FbpA-mediated transport of iron across the periplasm and into the cytosol[FbpA] (Mus musculus) PubMed
3160.
NfuA could act as a scaffold/chaperone for damaged Fe/S proteins (Mus musculus) PubMed
3161.
observed partial release of trapped calcein following activation of MscL was attributed to the formation of a long-lived subconductance state of MscL following channel opening[ MscL] (Mus musculus) PubMed
3162.
represents the first use of fluorescence approaches to estimate MsbA binding affinities for nucleotides and putative transport substrates[ MsbA] (Mus musculus) PubMed
3163.
This study reveals hierarchical action of two well-conserved sRNAs in a complex regulatory cascade that controls the glmS mRNA.[glmS] (Mus musculus) PubMed
3164.
The electron paramagnetic resonance results for ColA reconstituted into liposomes of E. coli lipids support the umbrella model for the closed channel state. (Colicin A) (Mus musculus) PubMed
3165.
Therefore, L0017 is a chaperone, the second chaperone identified in this system after CesAB, and escorts EspA, a protein with a great tendency to polymerize.[L0017] (Mus musculus) PubMed
3166.
colicin D treatment induce A-site mRNA cleavage in Escherichia coli along with amino acid starvation (Mus musculus) PubMed
3167.
interaction of RecX protein and RecA may enable an enhanced DNA binding by RecX protein[SSB and RecA] (Mus musculus) PubMed
3168.
The crystal structure of YdcF reveals a fold of the adenine nucleotide hydrolase-like family. YdcF binds S-adenosyl-L-methionine (AdoMet) with a Kd value of 25 M.[YdcF] (Mus musculus) PubMed
3169.
A novel cell division factor ZapB was identified in Escherichia coli that simultaneously stimulates Z ring assembly and cell division. [ZapB] (Mus musculus) PubMed
3170.
role of Mg(2+) is to overcome a kinetic barrier to melting of the DNA by RecBC and presumably also by RecBCD[RecBC] (Mus musculus) PubMed
3171.
identify the residues involved directly in binding of substrate to the inward-facing conformation of GlpT, thus defining the structural basis for the substrate-specificity of this transporter[GlpT] (Mus musculus) PubMed
3172.
tetracycline (Tc) plays the role of a specific Mg(2+) carrier, whereas the Mg(2+) ion itself makes key interactions that trigger the allosteric transition in the TetR:Tc complex[Tet repressor] (Mus musculus) PubMed
3173.
During infection, iutA expression was increased 50-fold in the airsac and in the lung 3, 6 and 24h post infection; ibeA expression was increased 2.5-9-fold in the airsac in the early stages of the infection only. [ibeA, iutA] (Mus musculus) PubMed
3174.
K48Q mutant of Escherichia coli Thymidylate synthase was studied using structural and biophysical methods.[Thymidylate synthase] (Mus musculus) PubMed
3175.
combination of hydrophobic and hydrophilic binding surfaces explains the ability of ePepN to cleave Lys, Arg, Phe, and Tyr[ aminopeptidase N] (Mus musculus) PubMed
3176.
FtsZ itself can assemble the Z ring and generate a force. No other proteins were needed for assembly and force generation. [FtsZ] (Mus musculus) PubMed
3177.
F41A mutation increases the K(M) for UDP-3-O-(R-3-OHC14)-GlcN 30-fold, consistent with aromatic stacking of the corresponding F43 side chain against the uracil moiety of bound UDP-GlcNAc in the X-ray structure of Chlamydia trachomatis LpxD[LpxD] (Mus musculus) PubMed
3178.
A conserved sequence-HRVW(279)QNRR--in delta subunit of gamma complex contributes to binding primer-template DNA (delta subunit of gamma complex). (Mus musculus) PubMed
3179.
These results support the hypothesis that LT is a more significant contributor than STb to the virulence of F4(+) ETEC infections in young F4ac receptor-positive pigs less than 2 weeks old. [LT, STb] (Mus musculus) PubMed
3180.
Crystal structure: AlkB uses an unprecedented base-flipping mechanism to access the damaged base (Mus musculus) PubMed
3181.
complete enzyme models for the oxidized and reduced states of all three Fe-bound SOD species were generated using combined quantum mechanics/molecular mechanics (QM/MM) geometry optimizations[iron superoxide dismutase] (Mus musculus) PubMed
3182.
Enteropathogenic Escherichia coli EspF was found to be responsible for decreased NHE3 activity; however, neither EspF-induced apoptosis nor the interaction of EspF with sorting nexin-9, an endocytic protein, were involved.[EspF] (Mus musculus) PubMed
3183.
resulting model for C-terminal E. coli IF2 indicates important structural differences between the aIF5B crystal structure and IF2 in solution[ translation initiation factor IF2 ] (Mus musculus) PubMed
3184.
Ionizable residues change their ionization state at acidic pH, thereby disrupting this network, modifying the electrostatic landscape near the channel gate, and favoring channel opening.[KcsA] (Mus musculus) PubMed
3185.
The structure of the Escherichia coli 5-methyluridine (m(5)U) 54 tRNA methyltransferase (MTase) TrmA in a covalent complex with a 19-nt T arm analog to 2.4-A resolution.[TrmA] (Mus musculus) PubMed
3186.
a surface type II beta-turn in the Escherichia coli protein EscU undergoes auto-cleavage by a mechanism involving cyclization of a strictly conserved asparagine residue; Structural analysis of SpaS [EscU; SpaS] (Mus musculus) PubMed
3187.
nucleotide excision repair proteins from E. coli recognize the purine-Cr(III) adduct but not the Cr(III)-backbone phosphate complex[UvrA, B and C] (Mus musculus) PubMed
3188.
analysis of nucleotide regulation of aspartate transcarbamoylase [ATCase] (Mus musculus) PubMed
3189.
conformational change of the insertase YidC upon biing a Pf3 coat protein molecule (YidC). (Mus musculus) PubMed
3190.
binding of misfolded proteins transforms hexameric DegP into large, catalytically active 12-meric and 24-meric multimers [DegP] (Mus musculus) PubMed
3191.
discussion of the principally different mechanisms of ribosome splitting by IF1/IF3 and by RRF/EF-G [initiation factor 1 and ribosome recycling factor] (Mus musculus) PubMed
3192.
The first crystal structure of a bacterial PTK, the C-terminal kinase domain of Escherichia coli Tyr kinase (Etk) at 2.5-A resolution, is reported.[Etk] (Mus musculus) PubMed
3193.
crystal structures of the Escherichia coli RecA-ssDNA and RecA-heteroduplex filaments [RecA] (Mus musculus) PubMed
3194.
19 ciprofloxacin-resistant clinical isolates of K. pneumoniae in pediatric patients in China were positive for the qnr gene [quinolone resistance gene /qnr gene] (Mus musculus) PubMed
3195.
The enhanced affinity for the operator element is mediated by a cooperative DNA binding by a pair of RelB dimers and that the interaction between RelB dimers is strongly augmented by the presence of the cognate toxin RelE.[RelB, RelE] (Mus musculus) PubMed
3196.
The slow kinetics of holoBirA dimerization combined with fluctuations in the intracellular apoBCCP pool are critical determinants in partitioning BirA between its distinct biological functions.[BirA] (Mus musculus) PubMed
3197.
stoichiometry of the subunit c rings remains constant even after reduction of the synthesis of subunit c[ATP synthase subunit c] (Mus musculus) PubMed
3198.
These results suggest that Stx2-induced apoptosis is mediated by CHOP in human brain microvascular endothelial cells (HBMEC) and involves activation of both the intrinsic and extrinsic pathways of apoptosis. (Mus musculus) PubMed
3199.
The results indicate that Asp142 and Asp447, located on the A1 and A2 halves of the protein, have different roles in ArsA catalysis, consistent with our proposal that these two halves are functionally nonequivalent.[ArsA] (Mus musculus) PubMed
3200.
The authors found that EspF from rabbit enteropathogenic Escherichia coli (E22) participates in the regulation of actin polymerization by binding to a complex of proteins at the tight junctions.[EspF] (Mus musculus) PubMed
3201.
The authors found that DraE-positive recombinant bacteria adhere to and are internalized by primary human bladder epithelial cells which express DAF and CEACAMs.[DraE] (Mus musculus) PubMed
3202.
An EAL domain protein, encoded by ydiV, and cAMP are involved in the interaction between the two Quorum sensing systems in E. coli.[ydiV] (Mus musculus) PubMed
3203.
YgjK is a glucosidase with relaxed specificity for sugars[YgjK] (Mus musculus) PubMed
3204.
Analysis of the amino acid sequences of subunits NuoM and NuoN in the membrane domain of Complex I revealed a clear common pattern, including two lysines that are predicted to be located within the membrane, important for quinone reductase activity.[NuoM] (Mus musculus) PubMed
3205.
The DeltaibeA mutant was less adhesive to human brain microvascular endothelial cells than the wild-type strain BEN2908 was.[IbeA] (Mus musculus) PubMed
3206.
These studies identify a correlation between the stability of the ExoI/SSB-C terminal complex and SSB-stimulation of ExoI activity.[Exo I, SSB] (Mus musculus) PubMed
3207.
Analysis of ATP substrate inhibition kinetics on ATP hydrolysis in hexameric PspF(1-275) indicates negative homotropic effects between subunits[PspF] (Mus musculus) PubMed
3208.
Presented is the first high pH structure of Escherichia coli aspartate transcarbamoylase;Alterations in the electropositive environment of the active site may be responsible for the enhanced activity of the enzyme at pH 8.5. (Mus musculus) PubMed
3209.
Our results indicate that LamB, OmpC and TolC are important OM proteins for tetracycline resistance in E. coli. [LamB, OmpC, TolC] (Mus musculus) PubMed
3210.
The regulation of the activity of quinolinate synthase (NadA) via disulfide bond formation between Cys291 and Cys294 is reported.[NadA] (Mus musculus) PubMed
3211.
The Asn378 residue of E. coli photolyase is crucial both for stabilizing the neutral flavin radical cofactor and for catalysis.[DNA photolyase] (Mus musculus) PubMed
3212.
Our results show that the acyltransferases that generate the secondary acyl chains of lipid A are members of the GPAT family and set the stage for structural studies.[LpxL] (Mus musculus) PubMed
3213.
REVIEW: mechanisms of YidC substrate recognition and membrane insertion with emphasis on its role in the assembly of multimeric membrane protein complexes such as the F1F0-ATP synthase [YidC] (Mus musculus) PubMed
3214.
Characterization of three independent intragenic second-site suppressors of the rne-1 and rne-3071 alleles that demonstrate the dissociation of the in vivo activity of RNase E on mRNA versus tRNA and rRNA substrates (RNase E). (Mus musculus) PubMed
3215.
Demonstration that biotin synthase catalyzes the stepwise addition of sulfur to dethiobiotin (biotin synthase). (Mus musculus) PubMed
3216.
an alternative proton pathway in E. coli succinate dehydrogenase that might be functional only in vitro (succinate dehydrogenase). (Mus musculus) PubMed
3217.
both DegP oligomers were also observed in extracts of E. coli cells, strongly implicating their physiological importance[ DegP ] (Mus musculus) PubMed
3218.
Polarity of helicase and fork arrest in vitro is generated by a mechanism that not only involves interaction between the terminator protein and the arrested enzyme but also of Tus with replication termini.[DnaB, Tus] (Mus musculus) PubMed
3219.
Site-directed spin labeling electron paramagnetic resonance spectroscopy was used to study the opening and closing of the nucleotide-binding interface of MalFGK(2) during the catalytic cycle.[MBP, MalFGK(2)] (Mus musculus) PubMed
3220.
An uneven binding of MinD to the heterogeneous native membrane is possible, leading to formation of a lipid-specific distribution pattern of MinD and/or modulation of its temporal behavior.[MinD] (Mus musculus) PubMed
3221.
the X-ray crystal structure of Escherichia coli regulator of nucleoside kinase (Rnk) at 1.9 (Mus musculus) PubMed
3222.
Changes in dynamics of a model membrane caused by MinD binding was studied using membrane-embedded fluorescent probes as reporters.[MinD] (Mus musculus) PubMed
3223.
The crystal structure of K4CP in the presence of UDP and UDP-GalNAc as well as with UDP and UDP-GlcUA was determined. (K4CP, chondroitin polymerase) (Mus musculus) PubMed
3224.
expression of FkpA-DsbAs conferred modest resistance to CuCl2, a phenotype that depends on disulfide bond isomerization[DsbC] (Mus musculus) PubMed
3225.
These results indicate that MacAB, an ATP-binding cassette transporter of MacB and its accessory protein, MacA, participates in the translocation of STII from the periplasm to the exterior. [MacAB] (Mus musculus) PubMed
3226.
analysis of chondroitin polymerase K4CP and the molecular mechanism of selective bindings of donor substrates to two active sites [K4CP] (Mus musculus) PubMed
3227.
These results are consistent with a role for BipA in either the structure or the function of the ribosome and imply that wild-type ribosomes are dependent on BipA for efficient expression of target messenger RNAs.[BipA] (Mus musculus) PubMed
3228.
activity of cytochrome bo(3) with long-chain ubiquinones appears to be different from previous reports using short-chain substrate analogues such as ubiquinol(UQ)-1 in that typical Michaelis-Menten kinetics are not observed using UQ-10[cytochrome bo3 ] (Mus musculus) PubMed
3229.
tRNase Z might help modulate a cell growth rate by repressing translation under some stressful conditions. (Mus musculus) PubMed
3230.
ClpA becomes largely resistant to autodegradation in the absence of its C-terminus and, conversely, transfer of the last 11 residues of ClpA to the C-terminus of green fluorescent protein (GFP) renders GFP a substrate of ClpAP.[ClpA, ClpP] (Mus musculus) PubMed
3231.
An alternative approach was applied to study the catalytic mechanism of alkaline phosphatase (AP), a widely studied prototypical bimetallo enzyme.[Alklaine phosphatase] (Mus musculus) PubMed
3232.
the involvement of external Ca2+ on cPHB synthesis regulated by the AtoS-AtoC two-component system, thus linking Ca2+ with a signal transduction system, most probably through a transporter. (Mus musculus) PubMed
3233.
the first kinetic characterization of the reaction between NO and iron-sulfur clusters in protein using the Escherichia coli IlvD (dihydroxyacid dehydratase) [4Fe-4S] cluster as an example (Mus musculus) PubMed
3234.
histidine 63 of MetAP-I affects the hydrolysis of small peptide substrates whereas large peptides can overcome the observed loss in binding energy, as predicted from K(m) values, by additional hydrophilic and hydrophobic interactions [MetAP-I] (Mus musculus) PubMed
3235.
The DNA translocation properties of EcoR124I complexes in which the HsdR subunits had been mutated in the RecB-like nuclease motif II or III, were examined.[EcoR124I] (Mus musculus) PubMed
3236.
Taken together, these results pinpoint three amino acids in CNF1 that are key amino acids for recognition by neutralizing MAb NG8 and further help define a region in CNF1 that is critical for full toxin binding to HEp-2 cells.[Cnf1] (Mus musculus) PubMed
3237.
MacA would facilitate the delivery of drugs by MacB to TolC by enhancing the binding of drugs to it and inducing a conformation of MacB that is primed and competent for binding TolC[MacB and MacA] (Mus musculus) PubMed
3238.
findings show Tir & EspF(U) are sufficient for actin pedestal formation in cells; EspF(U) repeats activate a protein complex containing N-WASP & WIP in vitro, suggesting the repeats cooperate to stimulate actin polymerization in vivo [EspF(U)] (Mus musculus) PubMed
3239.
we confirm by direct measurements of Cl- and H+ fluxes a Cl--to-H+ exchange stoichiometry of 2, and summarize experimental facts pertinent to the exchange mechanism [CLC-ec1] (Mus musculus) PubMed
3240.
The medium-resolution structure of MenD from Escherichia coli (EcMenD) in complex with its cofactor and Mn2+ has been determined in two related hexagonal crystal forms.[MenD] (Mus musculus) PubMed
3241.
The 2'-OH of A76 of tRNA(Thr) and a conserved active-site histidine (His-309) collaborate to catalyze aminoacyl transfer by a mechanism distinct from HisRS.[ThrRS] (Mus musculus) PubMed
3242.
The distribution in the F(O)F(1) structure of compliant and stiff domains, was investigated.[F0F1ATPase] (Mus musculus) PubMed
3243.
Skp does not only serve as a specialized chaperone for a small set of outer membrane proteins, but it seems to exhibit a broader substrate spectrum, including soluble periplasmic proteins.[Skp] (Mus musculus) PubMed
3244.
crystal structures also provide detailed insights into the mechanism of carbon-mercury bond cleavage by MerB[MerB] (Mus musculus) PubMed
3245.
ppGpp/DksA responsive sigma(54)-transcription in the environmentally adaptable P. putida was found to be more robust under low energy conditions that occur upon nutrient depletion[RNA Polymerase Sigma 54 and DksA] (Mus musculus) PubMed
3246.
Analysis on substrate specificity of Escherichia coli ribonuclease P using shape variants of pre-tRNA: proposal of subsites model for substrate shape recognition (ribonuclease P). (Mus musculus) PubMed
3247.
Cells lacking rodZ no longer had rod shape but rather were round or oval. (Mus musculus) PubMed
3248.
Four loop-forming sections of the chain were probed for the time course of loop formation during refolding of Escherichia coli adenylate kinase.[Adenylate kinase] (Mus musculus) PubMed
3249.
DraE or AfaE-III adhesin subunits are necessary and sufficient to promote the receptor-mediated bacterial internalization into epithelial cells expressing human decay-accelerating factor (DAF), CEACAM1, CEA, or CEACAM6.[DraE & AfaE-III] (Mus musculus) PubMed
3250.
The authors show that clustering transfers Tir into cholesterol-rich detergent-resistant microdomains (DRMs), a signal prompting transient c-Fyn accumulation at bacterial adhesion sites.[Tir] (Mus musculus) PubMed
3251.
Hma is a high-affinity receptor for heme, and heme uptake is required by uropathogenic Escherichia coli for kidney infection. [Hma] (Mus musculus) PubMed
3252.
Fcf1 and Fcf2 from E. coli O52 were expressed, purified and assayed for their respective activities. (Fcf1) (Fcf2) (Mus musculus) PubMed
3253.
The one-electron activation of the cluster, coupled to catalytic recycling of the superoxide anion back to oxygen via superoxide dismutase and catalase, provides a novel means of amplifying the sensitivity of [4Fe-4S](2+) FNR to its signal molecule.[FNR] (Mus musculus) PubMed
3254.
The ability of SecB-bound substrates to continue folding while bound to SecB and their ability to interact with other components of the secretory machinery may be key opposing determinants that inhibit and promote protein export, respectively.[SecB] (Mus musculus) PubMed
3255.
The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate. (Mus musculus) PubMed
3256.
Structure of a xenon derivative of Escherichia coli copper amine oxidase: confirmation of the proposed oxygen-entry pathway (Mus musculus) PubMed
3257.
Thiol peroxidase (Tpx) forms a mixed-disulfide complex with cytoplasmic thioredoxin 1 (Trx1), indicating that Tpx localizes in the cytoplasm. [Tpx] (Mus musculus) PubMed
3258.
The characterization of the HicA protein as a member of a multigene toxin-antitoxin gene family is reported.[HicA] (Mus musculus) PubMed
3259.
The role of five toxin-antitoxin systems in E. Coli were evaluated, including the role of YjgK.[YjgK] (Mus musculus) PubMed
3260.
EtpA, a TPS exoprotein adhesin of enterotoxigenic E. coli, mimics and interacts with highly conserved regions of flagellin, the major subunit of flagella, and that these interactions are critical for adherence and intestinal colonization [EtpA] (Mus musculus) PubMed
3261.
These data support a conserved three-state chaperone cycle where the conformational equilibrium varies between species, implicating evolutionary tuning to meet the particular client protein and metabolic environment of an organism.[HtpG] (Mus musculus) PubMed
3262.
the redox potential of thioredoxin 2, the pK(a) of the active site nucleophilic cysteine, as well as the stability of the oxidized and reduced form of the protein (Mus musculus) PubMed
3263.
This study present results showing that the leucine-responsive regulatory protein, Lrp, is involved in this phenotype by acting as a positive regulator of YojI, a chromosomally encoded efflux pump which expels microcin out of cells.[Lrp; YojI] (Mus musculus) PubMed
3264.
This study suggested that iron-dependent regulation of FimE via IscR leads to decreased surface attachment and biofilm dispersal under iron-limiting conditions.[IscR; FimE] (Mus musculus) PubMed
3265.
The role of cAMP receptor in the expression of heat-labile toxin in enterotoxigenic E. coli was studied.[LT-I] (Mus musculus) PubMed
3266.
Loss of RodZ leads to misassembly of MreB into non-spiral structures, and a consequent loss of cell shape.[MreB, RodZ] (Mus musculus) PubMed
3267.
ParM filaments were identified in E.coli; small bundles of three to five intracellular ParM filaments that were situated close to the edge of the nucleoid were observed (Mus musculus) PubMed
3268.
Distinct activities of Escherichia coli small heat shock proteins IbpA and IbpB promote efficient protein disaggregation (Mus musculus) PubMed
3269.
These data demonstrate that S10 and NusB together form a BoxA-binding module, that NusB facilitates entry of S10 into the transcription machinery, and that S10 represents a central hub in processive antitermination.[NusB, NusE] (Mus musculus) PubMed
3270.
CycA mRNA is a target for both GcvB and Hfq regulation. [CycA, Hfq] (Mus musculus) PubMed
3271.
HfQ-GcvB interaction is necessary for GcvB mediated regulation of OppA and DppA and to facilitate RNA-RNA pairing of GvcB with its target mRNAs. [Hfq, OppA, OppB] (Mus musculus) PubMed
3272.
Two mechanisms by which the hot dog-fold thioesterase EntH can potentially prevent or reverse EntB misacylation, are shown.[EntH] (Mus musculus) PubMed
3273.
GTP hydrolysis on EF-Tu is controlled through a hydrophobic gate mechanism.[EF-Tu] (Mus musculus) PubMed
3274.
structures of gp23-chaperonin complexes, showing both the initial captured state and the final, close-to-native state with gp23 encapsulated in the folding chamber [GroEL] (Mus musculus) PubMed
3275.
We have identified and characterized a novel TTSS-dependent effector protein (Ibe) of EPEC and EHEC strains that interacts with the host cell scaffolding protein, IQGAP1. [Ibe] (Mus musculus) PubMed
3276.
These data establish the specific structural features of this noncatalytic domain of TraI that are essential to DNA conjugation. (Mus musculus) PubMed
3277.
YmdB functions by interacting with a site in the RNase III catalytic region, that expression of YmdB is transcriptionally activated by both cold-shock stress and the entry of cells into stationary phase [YmdB and RNase III; substrain not found] (Mus musculus) PubMed
3278.
The antibiotic resistance conferred by Cfr is provided by methylation at the 8 position and is independent of methylation at the 2 position of A2503 of 23S rRNA. (Mus musculus) PubMed
3279.
DegS stimulation can be regulated by outer-membrane porins peptide affinity for the active and for the inactive protease conformations, as well as by preferential substrate binding to active DegS.[DegS] (Mus musculus) PubMed
3280.
An liquid chromatography-mass spectrometry study revealed some heterogeneity in terms of molecular mass of a cysteine-free mutant of dihydrofolate reductase (DHFR) after long storage of the highly purified protein as an ammonium sulfate precipitate.[DHFR] (Mus musculus) PubMed
3281.
The active domain of colicin E5 (E5-CRD) was expressed in Saccharomyces cerevisiae and its effects on growth, was investigated.[Colicin E5] (Mus musculus) PubMed
3282.
The membrane-bound closed channel structure of helices 4 and 5 (Lys-406-Asp-446) of the colicin E1 channel domain was investigated by using a site-directed fluorescence labeling technique.[Colicin E1] (Mus musculus) PubMed
3283.
the bacterial actin homolog MreB participates in the temporal oscillation of Topo IV activity (Mus musculus) PubMed
3284.
Here, the authors show that an approximately 55-kDa fragment of CNF1, which contains the catalytic domain and an additional part of the toxin, is present in the cytosol.[Cnf1] (Mus musculus) PubMed
3285.
YcgF does not degrade the signaling molecule c-di-GMP, but directly binds to and releases the MerR-like repressor YcgE from its operator DNA upon blue-light irradiation [ycfF] (Mus musculus) PubMed
3286.
The authors identified a region in the the heat-labile enterotoxin LT distinct from the pocket involved in eukaryotic receptor binding that is responsible for binding to the surface of E. coli. (Mus musculus) PubMed
3287.
findings indicate that a single cleft in the beta sliding clamp is sufficient for both loading and stimulation of Pol III replication, but both clefts are required for unloading clamp from DNA after replication is completed (beta sliding clamp). (Mus musculus) PubMed
3288.
The authors show that IRSp53 family members, key regulators of membrane and actin dynamics, directly interact with both Tir and EspF(U). (Mus musculus) PubMed
3289.
Structural and biochemical analyses revealed that the E. coli YrdC protein binds ATP and preferentially binds RNA(Thr) lacking only the threonylcarbamoyladenosine modification. (Mus musculus) PubMed
3290.
NMR structures of a mutant of E. coli RelE toxin, RelE(R81A/R83A), with reduced toxicity and its complex with an inhibitory peptide from RelB antitoxin, RelB(C) (Lys(47)-Leu(79)), have been determined.[RelE, RelB] (Mus musculus) PubMed
3291.
The mechanism of the four-electron reduction of dioxygen by a multicopper oxidase, CueO, was studied based on reactions of single and double mutants with Cys(500), a type I copper ligand, and the noncoordinating Asp(112) and Glu(506). [CueO] (Mus musculus) PubMed
3292.
A previously characterized hypermorphic mutant FtsA (FtsA*) partially disassembled FtsZ polymers in vitro.[FtsA, FtsZ] (Mus musculus) PubMed
3293.
studies suggested that the ibeR gene was involved in regulating stationary-phase gene expression related to stress resistance and pathogenesis [IbeR] (Mus musculus) PubMed
3294.
The solution nuclear magnetic resonance structure of a truncated version of SlyD (1-165) from Escherichia coli (SlyD*) that lacks the presumably unstructured C-terminal tail, was determined.[SlyD] (Mus musculus) PubMed
3295.
lipid insertion instigates a global conformational change in colicin Ia and more than one molecule participates in the channel architecture with the vestibule, possibly facilitating the large scale peptide translocation upon channel opening[COLICIN IA] (Mus musculus) PubMed
3296.
YihU is a novel gamma-hydroxybutyrate dehydrogenase involved in the metabolism of succinic semialdehyde, and other potentially toxic intermediates that may accumulate under stress conditions in E. coli[YIHU] (Mus musculus) PubMed
3297.
Bundlin contains an N-acetyllactosamine-specific carbohydrate-binding domain. [bundlin] (Mus musculus) PubMed
3298.
In this work, four single tryptophan (Trp) mutants of the dimeric mannitol transporter of Escherichia coli, EII(mtl), are characterized using Trp and 5-fluoroTrp (5-FTrp) fluorescence spectroscopy (Mus musculus) PubMed
3299.
Two substitutions in DksA, L15F and N88I, result in higher DksA activity both in vivo and in vitro, primarily by increasing the apparent affinity of DksA for RNA polymerase.[DksA] (Mus musculus) PubMed
3300.
MzrA is a type II membrane protein that specifically interacts with EnvZ but not with OmpR or the related membrane sensor kinase, CpxA. [MzrA] (Mus musculus) PubMed
3301.
Here, we report the crystal structure of the C-terminal nuclease domain of RecE at 2.8 A resolution (Mus musculus) PubMed
3302.
SecY channel loosely sealed, or with a plug locked open, does not, however, lead to general membrane permeability.[SecY] (Mus musculus) PubMed
3303.
The results support an alternating site model for catalysis in HisRS that may prove to be common to other class II aminoacyl-tRNA synthetases.[HisRS] (Mus musculus) PubMed
3304.
Subunit a of the F(1)F(0) ATP synthase (F(0)a) is strictly dependent on Ffh, SecYEG and YidC for its membrane insertion but independent of the proton motive force.[YidC, SecYEG, F0a] (Mus musculus) PubMed
3305.
The effect of the initial binding process was examined in vitro by fluorescence quenching of the tryptophan (Trp) residues of YidC which are highly sensitive fluorescent probes for changes of the protein's tertiary structure.[YidC] (Mus musculus) PubMed
3306.
The structure of three secondary transporter proteins, GltT of Bacillus stearothermophilus, CitS of Klebsiella pneumoniae, and GltS of Escherichia coli, was studied.[GltS] (Mus musculus) PubMed
3307.
Three aspects of FtsZ filament dynamics at steady state: rates of GTP hydrolysis, subunit exchange between protofilaments, and disassembly induced by dilution or excess GDP, were measured.[FtsZ] (Mus musculus) PubMed
3308.
Because the binding of 3-isopropylmalate(IPM)to 3-isopropylmalate dehydrogenase (IPMDH) is associated with a hinge-bending domain closure, the more intense hinge-bending fluctuations at higher temperatures increasingly interfere with IPM binding[IPMDH] (Mus musculus) PubMed
3309.
The prevalence of espM and espT in enteropathogenic and enteroemhorrhagic Escherichia coli strains isolated from humans is reported.[espM; espT] (Mus musculus) PubMed
3310.
The effects of synthetic signal peptides, wild-type (WT) and export-defective mutant (MT) of ribose-binding protein, on the conformational changes of signal recognition particle 54 homologue (Ffh) in Escherichia coli, was examined.[Ffh, RbsB] (Mus musculus) PubMed
3311.
The crystallographic results and the lack of functional cysteine residues in the active site of YfcG suggests that the reductase activity is unique in that no sulfhydryl groups in the YfcG protein are covalently involved in the redox chemistry.[YfcG] (Mus musculus) PubMed
3312.
A beta1,3-galactosyltransferase (WbgO) was identified in Escherichia coli O55:H7; WbgO requires a divalent metal ion, either Mn(2+) or Mg(2+), for its activity. [beta1,3-galactosyltransferase (WbgO)] (Mus musculus) PubMed
cglD deletion in E. coli K1 leads to prolonged survival of neonatal rats in experimental meningitis, without affecting the penetration of E. coli K1 through the blood-brain barrier. [CglD] (Mus musculus) PubMed
3315.
Outer membrane protein A (OmpA) inhibits cellulose production through the CpxRA stress response system, and this reduction in cellulose increases biofilm formation on hydrophobic surfaces. [OmpA/CpxR/CpxA/E.coli K12 BW25113] (Mus musculus) PubMed
3316.
active form of DNA polymerase V is UmuD'(2)C-RecA-ATP [umuD, umuC & recA] (Mus musculus) PubMed
3317.
Folding via a three-helical species stabilised by both native and non-native interactions is an essential feature of Im7 folding, independent of the helical propensity of helix III.[colicin e7 immunity protein Im7] (Mus musculus) PubMed
3318.
Activation of SoxR can occur in a DNA-mediated reaction with guanine radicals, an early genomic signal of oxidative stress, serving as the oxidant.[SoxR] (Mus musculus) PubMed
3319.
Substrate molecules bind on the periphery of the TatBC complex and that substrate binding causes a significant reduction in diameter of the TatBC part of the complex.TatB, TatC] (Mus musculus) PubMed
3320.
katP contributes to the complex gene network protecting E. coli strain 43895 from peroxide-mediated oxidative damage in an OxyR-dependent manner. [katP] (Mus musculus) PubMed
3321.
The cloning and characterization of a new class 1 integron carrying an ISCR1 element in E. coli clinical strains harboring the blaCMY-11 gene are reported.[blaCMY-11; ISCR1] (Mus musculus) PubMed
3322.
The allelic variations of eae, bfpA, and perA proteins in typical and atypical E. coli in a cohort of Peruvian children with diarrhea are reported.[eae] (Mus musculus) PubMed
3323.
overall rate-limiting step of the enzymatic reaction seems to be the release of Fpg from its adduct with the 4-oxo-2-pentenal remnant of the deoxyribose moiety formed as a result of DNA strand cleavage by beta,delta-elmination [fpg] (Mus musculus) PubMed
3324.
The first crystallographic model of the MukB hinge domain, is reported.[MukB] (Mus musculus) PubMed
3325.
dissociation of product RNA from tRNA-guanine transglycosylase is overall rate-limiting in the steady state [TGT] (Mus musculus) PubMed
3326.
Transmission electron microscopy reveals the accumulation of aberrant intracellular membranes when LpxB is overexpressed [LpxB] (Mus musculus) PubMed
3327.
important regulatory component of the cascade that governs the expression of LEE operons and the resulting ability of EHEC O157:H7 to intimately adhere to host cells.[Hha] (Mus musculus) PubMed
3328.
StcE protease contributes to intimate adherence of EHEC to host cells by cleavage of glycoproteins from the cell surface [StcE protease] (Mus musculus) PubMed
3329.
The effects of ClpXP on the type III protein secretion system through regulation of RpoS and GrlR in EHEC 0157 is reported. [GrlR] (Mus musculus) PubMed
3330.
These results show that that quorum sensing regulators B and C (QseBC) are transcribed in an operon, and that QseB may act to autoregulate its own transcription through binding to low- and high-affinity sites found in its promoter [qseB,C]. (Mus musculus) PubMed
3331.
NleC is translocated into host cells via enterocyte effacement-encoded type III secretion system. (NleC) NleD is translocated into host cells via enterocyte effacement-encoded type III secretion system. (NleD) (Mus musculus) PubMed
3332.
GrlA-dependent repression of the flagellar regulon is important for efficient cell adhesion of EHEC to host cells [GrlA] (Mus musculus) PubMed
3333.
Ehx levels were not induced in the grlR grlA double mutant strain but increased markedly by overexpression of GrlA even in the ler mutant, indicating that GrlA is responsible for this regulation.[GrlA] (Mus musculus) PubMed
3334.
EspL2 of E. coli O157:H7 Sakai bound F-actin-aggregating annexin 2 directly, increasing its activity.[EspL2] (Mus musculus) PubMed
3335.
GadE is critical for the acid resistance and plays an role in virulence. [GadE] (Mus musculus) PubMed
3336.
The authors demonstrated that the association between the enterohemorrhagic Escherichia coli O157:H7 EspFu and IRSp53 induces dynamic membrane remodeling in epithelial cells.[ EspFu] (Mus musculus) PubMed
3337.
it is demonstrated that NikR can regulate H. pylori nickel metabolism by directly controlling transcriptional repression of NixA-mediated nickel uptake and transcriptional induction of urease expression.[NikR] (Mus musculus) PubMed
3338.
detailed comparison of the quinol:fumarate reductase enzymes from C. jejuni and H. pylori with that of W. succinogenes [QFR] (Mus musculus) PubMed
3339.
Virulence factor CagA induces human gastric epithelial cell (GEC) production of macrophage migration inhibitory factor that in turn up-regulates procarcinogenic GEC events. [CagA] (Mus musculus) PubMed
3340.
CznABC metal export functions of H. pylori are essential for gastric colonization and underline the extraordinary importance of metal ion homeostasis for survival of H. pylori in the gastric environment. (CznA, CznB, CznC) (Mus musculus) PubMed
3341.
The participation of a cluster consisting of surface-exposed histidines is not present in this protein in Helicobacter pylori. {nikR] (Mus musculus) PubMed
3342.
H. pylori NikR controls nickel-responsive expression of the HP1400 (FecA3) and HP1512 (FrpB4) OMPs. (NikR) (Mus musculus) PubMed
3343.
studies indicate that high levels of AhpC are not required for in vitro growth or for primary gastric colonization.[AhpC] (Mus musculus) PubMed
3344.
An extreme carboxy terminal region and an adjacent unique 34 amino acid insertion region were found to be essential for DnaB helicase activity (DnaB helicase). (Mus musculus) PubMed
3345.
This study provided the first evidences that the single cysteine residue of HpPPase (Helicobacter pylori inorganic pyrophosphatase) was involved in enzyme activation, thermostability, and stabilization of quaternary structure. [HpPPase] (Mus musculus) PubMed
3346.
Phe181Pro mutation within the alpha7-beta8 loop disrupts the hexamerization of Quinolinic acid phosphoribosyltransferase, and the resultant dimer shows dramatically reduced protein stability and no activity (Quinolinic acid phosphoribosyltransferase). (Mus musculus) PubMed
3347.
Our data indicate that CagF binding precedes recognition of the C-terminal CagA translocation signal, and that both steps are required to recruit CagA to the type IV translocation channel.[CagF, CagA] (Mus musculus) PubMed
3348.
Characterization of a waaF mutant of Helicobacter pylori strain 26695 provides evidence that an extended lipopolysaccharide structure has a limited role in the invasion of gastric cancer cells (Mus musculus) PubMed
3349.
Carbonic anhydrases (alpha and beta) contribute to the urease-dependent response to acidity of H. pylori and are required for high-grade inflammation and efficient colonization by some strains.[alpha carbonic anhydrase, beta carbonic anhydrase] (Mus musculus) PubMed
3350.
TlpD was found to mediate a repellent tactic response away from conditions of reduced electron transport.(TlpD) (Mus musculus) PubMed
3351.
These results suggest that delivery of CagA into epithelial cells by the bacterial type IV secretion system is mediated in a cholesterol-dependent manner. (Mus musculus) PubMed
3352.
Aldo-keto reductase reduces a range of aromatic aldehyde substrates with high catalytic efficiency, and exhibits dual cofactor specificity for both NADPH and NADH (Aldo-keto reductase). (Mus musculus) PubMed
3353.
AddAB and RecA are required for efficient colonization of the stomach of mice, RecA more than AddAB.(AddA) (Mus musculus) PubMed
3354.
Inactivation of the arsS (HP0165)and arsR results in a 10-fold SabA-dependent(HP0725) increase in adherence to gastric epithelial cells in strain J99 but not in strain 26695.[ArsR] (Mus musculus) PubMed
3355.
Biochemical and genetic analyses of restriction endonuclease and a DNA methyltransferase activity encoded by the locus HP0502/0503/0504/0505 (HP0502/0503/0504/0505). (Mus musculus) PubMed
3356.
Helicobacter pylori (Hp) SSB bound specifically to ssDNA and modulated the enzymatic ATPase and helicase activity of HpDnaB helicase[Dnab and single-stranded DNA binding protein] (Mus musculus) PubMed
3357.
Thus, nonphosphorylated CagA activity contributes to the epithelial proliferative and proinflammatory responses associated with development of chronic gastritis and gastric cancer.[CagA] (Mus musculus) PubMed
3358.
The Helicobacter pylory single-stranded DNA (ssDNA)-binding protein (SSB) monomer folds as an oligonucleotide/oligosaccharide binding fold with a Y-shaped conformation. (Mus musculus) PubMed
3359.
Effect of FliK mutation on the transcriptional activity of the {sigma}54 sigma factor RpoN in H pylori. FliK appears to be involved in three processes: hook-length control, export substrate specificity and control of RpoN transcriptional activity. [FliK] (Mus musculus) PubMed
3360.
The results indicate that function of ORF390 in WSSV is a kind of apoptotic suppressor (ORF390) (Mus musculus) PubMed
3361.
identified VP664 as major structural protein that forms stacked rings in nucleocapsid [VP664] (Mus musculus) PubMed
3362.
vp15 functions as histone-like DNA-binding protein with preference to supercoiled DNA suggesting it is involved in the packaging of the WSSV genome in the nucleocapsid. [VP15] (Mus musculus) PubMed
3363.
VP31 might play an important role in infectivity of this virus [VP31] (Mus musculus) PubMed
3364.
nonstructural protein VP9 has been identified and expressed in Escherichia coli, purified and crystallized (VP9 nonstructural protein) (Mus musculus) PubMed
3365.
The crystal structure of VP9 revealed a ferredoxin fold with divalent metal ion binding sites. (VP9) (Mus musculus) PubMed
3366.
an analysis of VP51 AND VP76 proteins in this virus[VP51 AND VP76] (Mus musculus) PubMed
data suggest that a complex involving SsaM and SpiC distinguishes between translocators and effector proteins, and controls their ordered secretion through the pathogenicity island 2 type III secretion system (Mus musculus) PubMed
3369.
IgaA is predicted to favor expression of the entire PhoP-PhoQ regulon based on its repression of the RcsC-YojN-RcsB phosphorelay[IgaA] (Mus musculus) PubMed
3370.
results indicate that both SopD and SopD2 contribute to virulence in mice and suggest a functional relationship between these two proteins during systemic infection of the host [SopD2] (Mus musculus) PubMed
3371.
the promoter binding ability of the PhoP and PmrA proteins occurring in low Mg2+ is correlated with phosphorylation of these proteins in vivo [PmrA] (Mus musculus) PubMed
3372.
involved in adherence of Salmonella enterica serovar Typhimurium to human cells [OmpD] (Mus musculus) PubMed
3373.
identification of genes regulated by PmrA and the roles of the identified genes in contributing to phenotypes associated with the PmrA-PmrB regulon [PmrA] (Mus musculus) PubMed
3374.
We investigated the role of the 5' untranslated region in the Salmonella pathogenicity island-1 type III secretion system-mediated secretion of SopE. [SopE] (Mus musculus) PubMed
3375.
PagL enzymatic deacylation is posttranslationally inhibited by membrane environments. [PagL] (Mus musculus) PubMed
3376.
findings show that cdgR[for c-diguanylate (c-diGMP) regulator] is required for the bacterium to resist host phagocyte oxidase in vivo [CdgR] (Mus musculus) PubMed
3377.
Full virulence of Salmonella typhimurium requires SseJ deacylase.(SseJ) (Mus musculus) PubMed
3378.
to understand how CobA and FldA interact, a computer model of a CobA.FldA complex was generated; results indicate that Arg-9 and Arg-165 are important for CobA.FldA docking but not to catalysis [CobA] (Mus musculus) PubMed
3379.
analysis of the spatial-temporal patterns of in vivo expression of genes of the PhoP and PmrA regulons and identification of the in vivo signals modulating their transcription [pmrA] (Mus musculus) PubMed
3380.
Salmonella enterica serovar Typhimurium with mutations in the ompS1 and ompS2 genes, which code for quiescent porins, were nevertheless highly attenuated for virulence in a mouse model, indicating a role in pathogenesis [OmpS1, OmpS2] (Mus musculus) PubMed
3381.
Wzzst expression controlled by PmrA/B and RcsC/YojN/RcsB systems. This suggests that the Wzzst protein is required under different environmental conditions.[Wzzst] (Mus musculus) PubMed
3382.
membranes of S.typhimurium contain a novel hydrolase that removes the 3'-acyloxyacyl residue of lipid A in the presence of 5 mM Ca2+. the gene is designated lpxR, by screening an ordered S. typhimurium genomic DNA library (LpxR) (Mus musculus) PubMed
3383.
PmrA-regulated lipopolysaccharide modifications aid Salmonella's survival and spread in non-host environments. [PmrA] (Mus musculus) PubMed
3384.
Changes in cell surface due to LPS alteration in ddhC and waaG mutants result in significant changes in the production of both curli and cellulose and biofilm formation[waaG, ddhC] (Mus musculus) PubMed
3385.
S. typhimurium PepN contributes significantly to cytosolic aminopeptidase activity and its role is manifested under selected stress conditions.[peptidase N] (Mus musculus) PubMed
3386.
These data suggest that protease resistance is a critical property that allows SodCI to function in the harsh environment of the phagosome to combat phagocytic superoxide.[SodCI protein] (Mus musculus) PubMed
3387.
A comparison of conformational differences that affect the structure of the active site between O-acetylserine sulfhydrylase A and O-acetylserine sulfhydrylase B (OASS-A and OASS-B). (Mus musculus) PubMed
3388.
Cooperation between the SipA domains F1, F2 and 'actin-binding' domain is required to promote Salmonella virulence.[SipA] (Mus musculus) PubMed
3389.
The native function of wild-type YhiT remains undetermined, but the collective results are consistent with a role as a general transporter of C4-dicarboxylates and other compounds with a similar basic structure.[YhiT] (Mus musculus) PubMed
3390.
Expression of CopA depends on CueR and this transporter and the multicopper oxidase, CuiD are essential for full copper tolerance under aerobic and anaerobic conditions. [CuiD] (Mus musculus) PubMed
3391.
Study shows that the three hydrogenase operons hyb, hya and hyd are expressed under different environmental conditions and are subject to control by different regulatory proteins.[hyb, hya, hyd] (Mus musculus) PubMed
3392.
Taken together, the results reveal a combined role for NorV and NrfA in NO detoxification under anaerobic conditions, and highlight the influence that growth conditions have on the sensitivity to NO of this pathogenic bacterium.[NorV] (Mus musculus) PubMed
3393.
CyaR (formerly RyeE) sRNA as an ompX repressor was identified;cyaR expression is tightly controlled by the cyclic AMP receptor protein, CRP.(CyaR) (Mus musculus) PubMed
3394.
The mechanism of pathogenesis involves the PmrA-PmrB two-component system, which is activated in vivo by direct or indirect means and regulates genes that modify lipopolysaccharide, aiding survival in host (and non-host) environments. [PmrA, PmrB] (Mus musculus) PubMed
3395.
the authors found that S. enterica serovar Typhimurium and S. flexneri activate different subtypes of phospholipase A(2), a critical enzyme involved in the liberation of arachidonic acid from cellular membranes.[phospholipase A2] (Mus musculus) PubMed
3396.
These results suggest that the hydrogenases hya, hyb and hyd are used to oxidize hydrogen in different stages of an infection.[hya, hyb, hyd in strain JSG210] (Mus musculus) PubMed
3397.
Mutations in the promoter region of ramA appear to play a role in the up-regulation of RamA and AcrAB, and RamA is an activator of the MDR regulation cascade in Salmonella Typhimurium.[RamA] (Mus musculus) PubMed
3398.
Hya alone oxidizes the bulk of H(2) produced during fermentation.[Hya in strain 14028s] (Mus musculus) PubMed
The results indicate that MviA regulates igaA transcription in an RpoS-dependent manner, but the results also suggest that MviA may regulate RcsB activation in an RpoS- and IgaA-independent manner. (Mus musculus) PubMed
3401.
The opgGH mutant strain poorly colonized mouse organs when introduced orally along with the wild-type strain.[OpgH] (Mus musculus) PubMed
3402.
Salmonella typhimurium showed a severe defect in motility and an attenuated phenotype in a competitive mouse infection experiment, where the DeltawbaP strain (SKI12) was directly compared to wild-type Salmonella.[wbaP] (Mus musculus) PubMed
3403.
SopB vaccination reduced the bacterial burden of organs by about 5-fold on day 4 and day 8 after challenge with virulent Salmonella and proved to be a more efficient vaccination strategy than live attenuated bacteria alone[SopB ] (Mus musculus) PubMed
3404.
Production of ArtA is induced by mitomycin C or H2O2, and ArtA is able to modify pertussis toxin-sensitive G proteins. [ArtA] (Mus musculus) PubMed
3405.
SpiC is involved in flagella assembly by affecting the post-transcription expression of flhDC. [SpiC] (Mus musculus) PubMed
3406.
ArcZ targets the coding sequence of tpx mRNA. Hfq is required for ArcZ mediated target repression. Overexpression alters the repertoire of Hfq-bound sRNAs. [ArcZ] (Mus musculus) PubMed
3407.
the intracellular survival of most S. Typhimurium bacteria is conferred by the PhoPQ two-component regulator (PhoPQ) (Mus musculus) PubMed
3408.
Omb is a previously unrecognized ferrous iron-binding protein. Omb may be involved in the acquisition of ferrous iron during the initial stages of SC infection and appears to be an important virulence factor. [omb/outer membrane beta-barrel protein] (Mus musculus) PubMed
3409.
results suggest that the left inverted terminal repeat contains the sole BAdV-3 E1A promoter [E1A] (Mus musculus) PubMed
3410.
E1B-156R, an early region 1B gene product of Adenovirus type 5, is a novel transformation-promoting E1B protein that acts without repressing p53 transactivation (E1B-156R). (Mus musculus) PubMed
3411.
Expression of PAdV-3 E1Blarge inhibited the NF-kappaB dependent transcription of luciferase from IL-8 promoter.[E1B large protein] (Mus musculus) PubMed
3412.
CUN085 is an occlusion body (OB) protein from the nucleopolyhedrovirus of Culex nigripalpus (CuniNPV) (Mus musculus) PubMed
3413.
first crystal of a coxsackievirus B3 RNA-dependent RNA polymerase is reported (Mus musculus) PubMed
3414.
Hypoxia-induced functional switch of complex II from succinate dehydrogenase to fumarate reductase, which subsequently leads to activation of voltage-gated calcium channels resulting in increased NO production by eNOS. (Mitochondrial complex II) (Mus musculus) PubMed
3415.
data provide the first evidence that (E)-4-Hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE) is a ferredoxin-dependent enzyme in Thermosynechococcus elongatus BP-1 (Mus musculus) PubMed
3416.
The isolation and characterization of NADH-quinone oxidoreductase-1 (NADH-1) in T. elongatus is reported.[NDH-1] (Mus musculus) PubMed
3417.
Neurofascin isoforms, Nfasc155 in glia and Nfasc186 in neurons, are required for assembly of nodal and paranodal domains of myelinated axons and are essential for transition to saltatory conduction in developing vertebrate nerves. (Nfasc155 and 186) (Mus musculus) PubMed
3418.
calcium ion is bound to the PsbO protein of photosystem II isolated from Thermosynechococcus elongatus. The Ca2+-binding site is located close to the lumenal exit of a putative proton channel leading from the water splitting site [PsbO] (Mus musculus) PubMed
3419.
These results suggest that the epsilon subunit of chloroplast-type ATP synthase plays an important regulator for the rotary motor enzyme, thus preventing wasteful ATP hydrolysis.[F1-ATPase epsilon] (Mus musculus) PubMed
3420.
PsbY is located in the periphery of photosystem II close to the alpha- and beta-subunits of cytochrome b559 (PsbY). (Mus musculus) PubMed
3421.
Structure of PBP-A from Thermosynechococcus elongatus, a penicillin-binding protein closely related to class A beta-lactamases (Mus musculus) PubMed
3422.
3C protease can localize in the nucleus and alter nucleocytoplasmic transport. [3C protease] (Mus musculus) PubMed
3423.
Open reading frame 29 (ha29) is a gene specific for Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus (Ha29 gene) (Mus musculus) PubMed
3424.
Increase of budded virus yield, decrease of virion production, and a smaller number of nucleocapsids produced in infected cells were result of fp25k deletion. No obvious changes of expression level of Ha133 and ODV-E66 were observed [FP25K] (Mus musculus) PubMed
3425.
deletion of the C terminus of the ha2 product, a phosphatidylinositol 4-kinase homolog, dramatically decreased the viral titer, while deletion of 128 aa from the N terminus did not affect HA2 function.[HA2] (Mus musculus) PubMed
3426.
espJ and tccP constitute an operon, whose expression in vitro is affected by the composition of the medium and environmental signals such as temperature, pH, osmolarity and O(2) pressure [espJ, tccP] (Mus musculus) PubMed
3427.
We found that secretion of OtpA into the extracellular environment in E. coli O157:H7 requires OtpB and that when OtpA was produced in an E. coli K-12 strain, its secretion was strictly dependent on the production of OtpB.[OtpA, OtpB] (Mus musculus) PubMed
3428.
the roles of NrfG in the formation of heme lyase complex (NrfEFG) and in the interaction between heme lyase complex and formate-dependent nitrite reductase (NrfA), we determined the crystal structure of NrfG at 2.05 A (Mus musculus) PubMed
3429.
study demonstrates that the phenotypic change occurring during mouse passage correlates with stress response of outer membrane protein W (OmpW); upon induction of oxidative stress, OmpW was highly expressed only in the stress-sensitive MP37 strain [OmpW] (Mus musculus) PubMed
3430.
Unlike other group III periplasmic binding proteins (PBPs), FitE forms dimers both in solution and in the crystals: [FitE] (Mus musculus) PubMed
3431.
These studies suggest that in strain 43895OR, the murein lipoprotein Lpp indirectly regulates CsgA expression through the CpxAR system by a posttranscriptional mechanism. [CsgA, Lpp] (Mus musculus) PubMed
3432.
REVIEW: Together, these regulatory proteins create a genetic circuit in which the cellular concentrations of CtrA and GcrA oscillate spatially and temporally to control daughter cell differentiation and cell cycle progression [CtrA] (Mus musculus) PubMed
3433.
The crystal structure of the unorthodox response regulator PleD from Caulobacter crescentus, which consists of two CheY-like receiver domains and a diguanylate cyclase domain, has been solved in complex with the product c-diGMP. (PleD) (Mus musculus) PubMed
3434.
experiments demonstrate that gyrB transcription does not require any auxiliary factors, suggesting that temporal regulation is not dependent upon an activator protein (Mus musculus) PubMed
3435.
The flaF gene is required for motility and flagellin protein synthesis. (Mus musculus) PubMed
3436.
data consistent with proposal that MalA actively transports maltodextrins; first example of an outer membrane protein for which an ExbB/ExbD-dependent transport of a nutrient other than iron & vitamin B(12) has been shown [MalA] (Mus musculus) PubMed
3437.
MreC may function in the spatial organization of penicillin-binding proteins as well as other proteins that lie outside the cytoplasmic membrane [MreC] (Mus musculus) PubMed
3438.
results show that DivL controls two key cell cycle regulators, CtrA and DivK, and that phosphoryl transfer is not DivL's essential cellular activity [DivL] (Mus musculus) PubMed
3439.
Study shows that MreC is required for the spatial organization of components of the peptidoglycan-synthesizing holoenzyme in the periplasm and MreB directs the localization of a peptidoglycan precursor synthesis protein in the cytosol. [MreB,MreC] (Mus musculus) PubMed
3440.
The xylX and at least one other promoter in the xylose regulon (PxylE) are controlled by the CC3065 (xylR) gene product, a LacI-type repressor.[XylR] (Mus musculus) PubMed
3441.
when deleted the tonB gene encoded by the cc2334a ORF abolished maltose transport [TonB] (Mus musculus) PubMed
3442.
NagA forms a small pore through which GlcNAc specifically diffuses into the periplasm and functions as an energy-coupled transporter for the larger chitin oligosaccharides.[NagA in strain JS1003] (Mus musculus) PubMed
3443.
Since SpoT controls (p)ppGpp abundance, the authors propose that this nucleotide relays carbon starvation signals to the cellular factors responsible for activating DnaA proteolysis, thereby inhibiting the initiation of DNA replication.[SpoT & DnaA] (Mus musculus) PubMed
3444.
crescentin also shares in vivo properties of assembly and dynamics with IF proteins by forming stable filamentous structures that continuously incorporate subunits along their length and that grow in a nonpolar fashion [crescentin] (Mus musculus) PubMed
3445.
ShpA is likely to share a common mechanism for molecular recognition and phosphotransfer with yeast phosphotransfer protein YPD1 despite their low overall sequence similarity. (Mus musculus) PubMed
3446.
analysis of structure, function, and targets of the transcriptional regulator SvtR from the hyperthermophilic archaeal virus SIRV1 [SvtR] (Mus musculus) PubMed
3447.
crystallization of the complement component-3-binding domain of Efb and presentation of the results of single and multiwavelength anomalous diffraction studies on these crystals [Efb] (Mus musculus) PubMed
3448.
results provide the first insight into the solution structure of full-length Eap and an experimental basis for interpreting the EAP domain crystal structures within the context of the full-length molecule [Eap] (Mus musculus) PubMed
3449.
Contribution of point mutations to vancomycin resistance [graR] (Mus musculus) PubMed
3450.
The specific binding of Efb to the putative receptor on the platelet surface results in a stimulated, non-functional binding of fibrinogen, distinct from natural binding of fibrinogen to platelets.(Extracellular fibrinogen binding protein, Efb) (Mus musculus) PubMed
3451.
a possible regulatory relationship between the MazEF(Sa) TA module and the pathogenicity in S. aureus[MazF] (Mus musculus) PubMed
3452.
hypothesized that SpyA is produced by S. pyogenes to disrupt cytoskeletal structures and promote colonization of the host [SpyA] (Mus musculus) PubMed
3453.
The proteolytic effect of SpeB on 5 S. pyogenes superantigens is reported; only SpeZ was completely degraded by the enzyme.[SpeZ] (Mus musculus) PubMed
3454.
amino acid requirements for IgG glycan-hydrolyzing activity of EndoS; findings show cysteine proteinase SpeB processes/degrades EndoS & emphasizes importance of SpeB as a degrading/processing enzyme of proteins from the bacterium itself [EndoS] (Mus musculus) PubMed
3455.
By degrading the host defense peptide IL-8, the SpyCEP protease impairs neutrophil clearance mechanisms. [SpyCEP] (Mus musculus) PubMed
3456.
SilCR upregulates the in vitro expression of sagA, siaA, and scpC, genes associated with S. pyogenes pathogenesis. [scpC] (Mus musculus) PubMed
3457.
Linkage of Cpa to T3 by the sortase family transpeptidase SrtC2 requires the VPPTG motif in the cell wall-sorting signal of Cpa. [Cpa; T3] (Mus musculus) PubMed
3458.
Here we provide evidence that, like Slmo, both the Prel and Retm proteins are localised to the mitochondria, indicating that the function of the PRELI/MSF1p' domain is specific to this organelle.[retm] (Mus musculus) PubMed
3459.
PsaR-mediated gene regulation in response to Mn2 is required for full virulence in the establishment of pneumonia. [PsaR] (Mus musculus) PubMed
3460.
the contribution of the blp locus, encoding putative bacteriocins and cognate immunity peptides, to intraspecies competition. (Mus musculus) PubMed
3461.
in vitro transcriptional changes in pneumococcal rr09 mutants of two strains, D39 and TIGR4, by microarray analysis [rr09] (Mus musculus) PubMed
3462.
The authors describe that the high calcium concentrations in the normal human host were toxic to pneumococci and that bacterial survival in vivo depended on CaxP, the first Ca2+ exporter reported in bacteria.[CaxP] (Mus musculus) PubMed
3463.
RitR functionally interacts with the S. pneumoniae Ser-Thr kinase-phosphatase pair StkP and PhpP. RitR is phosphorylated by StkP at the C-terminal DNA-binding domain. [RitR; StkP; PhpP] (Mus musculus) PubMed
3464.
The contribution of PpmA to virulence can be explained by its strain-specific role in adherence to epithelial cells and contribution to the evasion of phagocytosis. [PpmA/proteinase maturation protein A] (Mus musculus) PubMed
3465.
assembly of the trimeric complex DivIB/DivIC/FtsL and co-localiation at division site is regulated through controlled formation of the DivIC/FtsL heterodimer. [DivIC] (Mus musculus) PubMed
3466.
A serotyping technique based on sequences of various capsular proteins (cpsA AND cpsB AND wzy AND wzx) (Mus musculus) PubMed
3467.
The role of the Yycf regulator on fatty acid biosynthesis and plasma membrane composition in Streptococcus pneumoniae. (Mus musculus) PubMed
3468.
The crystal structure of virulence factor choline-binding protein e.(virulence factor choline-binding protein e). (Mus musculus) PubMed
3469.
findings support the conclusion that the VicR response regulator strongly and directly regulates the transcription of a set of genes encoding the important surface proteins PspA and PcsB [PcsB, VicR] (Mus musculus) PubMed
3470.
In this study, it was found that PcsB localizes to the plasma membrane and is released into the growth environment, yet it is detectable on the pneumococcal surface by flow cytometry analysis.[PcsB protein] (Mus musculus) PubMed
3471.
Deletion replacement mutation in stkP conferred hypersensitivity to penicillin G. [StkP] (Mus musculus) PubMed
3472.
Study presents the crystal structure of ORF14 of SIFV (Lipothrixviridae), a protein of 112 residues which has homologues in other archaeal viruses; SIFV-14 has a domain swapped structure and forms fiber structures in the crystal.[SIFV-14] (Mus musculus) PubMed
3473.
Sip2 and Sip3 proteins, putative type I signal peptidases, are inhibited by arylomycin A2. [Sip2; Sip3] (Mus musculus) PubMed
3474.
Critical residues for GP folding and viral entry identified in Ebola virus GP1 are conserved in Marburg virus. (Mus musculus) PubMed
3475.
experiments demonstrated that mannose-binding lectin (MBL) binds to envelope glycoprotein resulting in important biological effects and suggest that MBL can interact with filoviruses during infection in humans [Env protein] (Mus musculus) PubMed
3476.
Mass spectroscopic analysis indicated that primed GP(1,2) contains residues 33 to 190 of GP(1) and all residues of GP(2).[GP1 & GP2] (Mus musculus) PubMed
3477.
cloned & overexpressed ArgF'in E. coli and show that it catalyzes the formation of N-acetyl-L-citrulline from N-acetyl-L-ornithine and carbamyl phosphate; designate this enzyme as an acetylornithine transcarbamylase [acetylornithine transcarbamylase] (Mus musculus) PubMed
3478.
Opioid-derived peptide beta-endorphin is present in the genital tract of stallion, but is not locally produced as in other mammalian and nonmammalian models. (Mus musculus) PubMed
3479.
data show that CmeR governs the expression of multiple genes with diverse functions and is required for Campylobacter adaptation in the chicken host [CmeR] (Mus musculus) PubMed
3480.
MsrA and MsrB make a significant contribution to the protection of C. jejuni against oxidative and nitrosative stress. [MsrA] (Mus musculus) PubMed
3481.
inhibition of respiration by NO may increase availability of oxygen for Cgb (part of NssR regulon) synthesis and function [Cgb/NssR] (Mus musculus) PubMed
3482.
TGBp1, TGBp2, and TGBp3 are differed in cellular localization. [TGBp1, TGBp2, TGBp3] (Mus musculus) PubMed
3483.
Te crystal structures of the open form RpiA from Vibrio vulnificus YJ106 (VvRpiA) in complex with the R5P and the closed form with arabinose-5-phosphate (A5P) in parallel with the apo VvRpiA at 2.0 A resolution, were determined.[RpiA] (Mus musculus) PubMed
3484.
Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), have key roles in mycolic acid biosynthesis in Corynebacterianeae [accD2, accD3] (Mus musculus) PubMed
3485.
activity og GlnK is regulated by adenylylation, cell membrane localization and degradation by at least three different proteases, FtsH, the ClpCP and the ClpXP protease complex in response to cellular nitrogen supply.[GlnK] (Mus musculus) PubMed
3486.
findings indicated that MtrAB is involved in cell wall metabolism and influences the expression of genes involved in osmoprotection [mtrA] [mtrB] (Mus musculus) PubMed
3487.
a gene (acnR) encoding a TetR-type transcriptional regulator was found to be encoded immediately downstream of the aconitase gene (acn) in C. glutamicum (Mus musculus) PubMed
3488.
Depletion of ClpP1 and ClpP2 resulted in the accumulation of ClgR, indicating that ClgR is in fact a substrate of the ClpCP1 and/or ClpCP2 protease in C. glutamicum.[ClgR] (Mus musculus) PubMed
3489.
PorH (C.glut), a cation-selective channel-forming protein, is coded in the bacterial chromosome by a gene that is localized in the vicinity of porA(C.glut), within a putative operon of 13 genes.[PorH(C.glut)] (Mus musculus) PubMed
3490.
findings show that an AraC-type regulator, termed RipA for "regulator of iron proteins A," is involved in regulation of the aconitase gene under iron limitation [RipA] (Mus musculus) PubMed
3491.
The isolation and characterization of RamA, a transcriptional activator, in C. glutamicum, is reported.[RamA] (Mus musculus) PubMed
3492.
results suggested that Cg2831 is a transcriptional activator of cspB gene expression in C. glutamicum (Mus musculus) PubMed
3493.
An experimental analysis of the membrane topology of Emb arabinofuranosyltransferase was presented. (Mus musculus) PubMed
3494.
ppk2B gene (NCgl2620) corresponds to putative class II polyphosphate kinase. [ppk2B] (Mus musculus) PubMed
3495.
During growth on media lacking L-lactate, LldR represses expression of quinone depedent L-lactate dehydrogenase. {LldR] (Mus musculus) PubMed
3496.
Data show AmtA has a high substrate affinity and mediates saturable, membrane potential-dependent transport, which resulting in a high steady-state accumulation of methylammonium, even in the absence of metabolic trapping [AmtA] (Mus musculus) PubMed
3497.
MptB as a PPM-dependent alpha(1-->6) mannosyltransferase, involved in early stages of proximal alpha(1-->6) core Cg-LM-A and Cg-LM-B biosynthesis in C. glutamicum. (Mus musculus) PubMed
3498.
Data revealed that DccT, which is a member of the divalent anion/Na(+) symporter family, catalyzes the effective uptake of dicarboxylates like succinate, fumarate, L-malate, and likely also oxaloacetate in a sodium-dependent manner [dccT] (Mus musculus) PubMed
3499.
a double AlaT and AvtA mutant was auxotrophic for L-alanine, showing that both ATs can provide L-alanine and that they are the only ATs involved.[AvtA] (Mus musculus) PubMed
3500.
DNA microarray and DNase I footprint analyses suggested that LldR acts as a repressor regulating cgl2917-lldD and cgl1934-fruK-ptsF operons, which are indispensable for l-lactate and fructose/sucrose utilization, respectively (LldR). (Mus musculus) PubMed
3501.
RbsR and UriR demonstrate a transcriptional co-control of the rbs and uriR operons and the rbsK2 gene, and recognize the same cognate DNA sequences in the operators of their target genes. [RbsR, UriR] (Mus musculus) PubMed
3502.
The authors provide experimental evidence that a potential potassium channel (CglK) acts as the major potassium uptake system in a bacterium and proved CglK's function directly in its natural membrane environment.[CglK] (Mus musculus) PubMed
3503.
The l-lactate dehydrogenase (Ldh) gene was shown to be regulated at the transcriptional level by SugR, a pleiotropic transcriptional repressor. [Ldh, SugR] (Mus musculus) PubMed
3504.
The study show that LldR is another protein that binds to the ldhA promoter region, thus regulating ldhA expression.LldR has hitherto been characterized as an L-lactate-responsive transcriptional repressor of L-lactate utilization genes. New Gene: LldR (Mus musculus) PubMed
3505.
These results suggest that the PS II-H protein is essential for stable assembly of native dimeric PS II complex containing PS II-X.[psII-x] (Mus musculus) PubMed
3506.
PixJ, like SyPixJ1, is a novel photoreceptor in cyanobacteria ('cyanobacteriochromes') that are similar, but distinct from the phytochromes and bacteriophytochromes [PixJ] (Mus musculus) PubMed
3507.
results indicated that the chromophore of TePixJ is not phycocyanobilin but its isomer, phycoviolobilin (PVB); it is suggested that the GAF domain of TePixJ has auto-lyase and auto-isomerase activities [PixJ] (Mus musculus) PubMed
3508.
The results indicate that Tyr8 is not indispensable for the accumulation of the red-shifted form of PixD at least at 80 K.[PixD] (Mus musculus) PubMed
3509.
The F1FO-ATP synthase of the thermophilic cyanobacterium Thermosynechococcus elongatus, was isolated and characterized.[F1FO ATP synthase] (Mus musculus) PubMed
3510.
CphA catalyzed in vitro cyanophycin synthesis in the absence of a primer. [CphA] (Mus musculus) PubMed
3511.
CrtG is a 2,2'-beta-hydroxylase involved in the biosynthetic pathway of the carotenoids nostoxanthin and 2-hydroxymyxol 2'-fucoside. [CrtG] (Mus musculus) PubMed
3512.
the interaction with the FADH(*)-Y8(*) state occurred after the second photoexcitation of the photoinduced red-shifted states in the photocycle of TePixD [PixD] (Mus musculus) PubMed
3513.
DNA sequence of the cloned ipaB was the same as ipaB from other Shigella flexneri. [ipaB] (Mus musculus) PubMed
3514.
OspB and OspF localize to nucleus of host cells, reduce the amount of IL-8 secretion, and associate with Rb. [OspB; OspF] (Mus musculus) PubMed
3515.
L* protein is shown to play an important role in virus persistence, TMEV-induced demyelination, and virus growth in macrophages. [L*] (Mus musculus) PubMed
3516.
IFP35 can interact with the bovine Tas (BTas) regulatory protein of bovine foamy virus; overexpression of IFP35 disturbs the ability of BTas to activate viral-gene transcription and inhibits viral replication. (Mus musculus) PubMed
3517.
These data suggest the dimerization region is necessary for the transactivational function of BTas and is crucial to the replication of Bovine foamy virus.[BTas] (Mus musculus) PubMed
3518.
BibA is a novel multifunctional protein involved in both resistance to phagocytic killing and adhesion to host cells [BibA protein] (Mus musculus) PubMed
3519.
prpZ, prkY and prkX are virulence genes that may be part of a signaling pathway controlling long-term survival of S. Typhi in host cells. [prpZ, prkY and prkX] (Mus musculus) PubMed
3520.
Smu0630 is critical for biofilm formation [Smu0630] (Mus musculus) PubMed
3521.
This study reveals that AtlA is a surface-associated protein that plays a critical role in the network connecting cell surface biogenesis, biofilm formation, genetic competence, and autolysis (Mus musculus) PubMed
3522.
This study illustrates the central role of AtlA and VicK in orchestrating growth on surfaces and envelope biogenesis in response to redox conditions.[AtlA] (Mus musculus) PubMed
3523.
LiaS sensor kinase regulates the expression of several genes coding for virulence factors. [LiaS] (Mus musculus) PubMed
3524.
CiaX is part of the cia operon, and is required for calcium-mediated autoregulation and calcium-mediated biofilm formation. [CiaX] (Mus musculus) PubMed
3525.
Compared to the parental strain UA159, the histidine kinase (liaS) mutant strain (IBS148) was more tolerant to various inhibitors that target protein synthesis, DNA synthesis and cell-wall biosynthesis. [LiaS] (Mus musculus) PubMed
3526.
ClpL, ClpX and ClpP plays roles in the expression of key virulence traits of S. mutans. [ClpL] (Mus musculus) PubMed
3527.
Under bacitracin stress conditions, the LiaFSR signaling system was shown to induce transcription of several genes involved in membrane protein synthesis, peptidoglycan biosynthesis, envelope chaperone/proteases, and transcriptional regulators.[LiaFSR] (Mus musculus) PubMed
3528.
This study reveals that the control of agmatine deiminase (AgDS) gene expression by both agmatine and low pH is coordinated through the AguR protein and begins to identify domains of the protein involved in sensing and signaling.[AguR] (Mus musculus) PubMed
3529.
In the presence of high concentrations of CSP pheromone, the unprocessed form of mutacin V acted as an intracellular auto-active bacteriocin causing S. mutans autolysis. [mutacin V] (Mus musculus) PubMed
3530.
vicR expression was not autoregulated and was downregulated by the CSP in a ComX-independent manner. Expression of vicRKX is influenced by culture pH, growth phase and antibiotic stress, and is regulated by LiaFRS. [VicR] (Mus musculus) PubMed
3531.
showed that CovS/CovR plays a major role in positively controlling S. agalactiae virulence [CovS][CovR] (Mus musculus) PubMed
3532.
Threonine phosphorylation of CovR reduces its activation at the conserved aspartate and diminishes its ability to bind DNA and control gene expression. [CovR] (Mus musculus) PubMed
3533.
ArcA is partially activated by a HptA, a small protein homologous to the histidine phosphotransfer domain of ArcB from E. coli [HptA] (Mus musculus) PubMed
3534.
expression of Msr fusion proteins in bacterial pathogens is consistent with important role for this enzyme in maintenance of protein function necessary for bacterial survival under highly oxidizing conditions [MsrBA] (Mus musculus) PubMed
3535.
Cultures grown under aerobic conditions with 25 microM copper showed significantly increased expression of cusA, whereas copA ighly induced under anaerobic conditions with 100 microM copper. [copA, cusA] (Mus musculus) PubMed
3536.
The results indicated that CyaC plays a major role in regulating anaerobic respiration and may contribute to additional signaling pathways independent of AMP receptor protein. New Gene: cyaC (Mus musculus) PubMed
3537.
We postulate that PsrA functions as the main subunit of the S. oneidensis S2O3(2-) terminal reductase whose end products (sulfide [HS-] or SO3(2-)) participate in an intraspecies sulfur cycle that drives S(0) respiration. [PsrA] (Mus musculus) PubMed
3538.
MtrC (reductase) is shown to be kinetically competent to catalyze soluble iron reduction in whole cells but is not responsible for electron transfer via direct contact alone with insoluble iron-containing minerals. [MtrC] (Mus musculus) PubMed
3539.
HlyU protein, a virulence factor up-regulates the expression of RtxA1 (repeats in toxin gene), a gene, responsible for cytotoxicity and virulence. [HlyU, RtxA1] (Mus musculus) PubMed
3540.
sigma28-dependent class 3 gene expression was unaffected by flagellar shearing but was affected by the growth phase of the cell. (sigma28) (Mus musculus) PubMed
3541.
appears to be one of 3 TTSS effector proteins in V. parahaemolyticus. [VPA450] (Mus musculus) PubMed
3542.
From these experiments, the authors concluded that there is a T3S-associated chaperone, VecA, for a cytotoxic T3SS1-dependent effector, VepA.[VecA & VepA] (Mus musculus) PubMed
3543.
null mutants of rpoH1, rpoE1, and rpoE2 are defective for survival in mice at 4 weeks postinfection. rpoH2 deletion strongly reduces the expression of two major virulence factors, the type IV secretion system and the flagellum.[rpoH1, rpoH2, rpoE1, rpoE2] (Mus musculus) PubMed
3544.
A second LuxR-type regulatory protein,BlxR, was identified in Brucella militensis.(BlxR) (Mus musculus) PubMed
3545.
data indicate that N-acetylglucosaminidase (AtlA) is not produced as a proenzyme and that control of the AtlA glucosaminidase activity is likely to occur at the level of LysM-mediated binding to peptidoglycan [AtlA] (Mus musculus) PubMed
3546.
The data suggest that two secreted and coregulated proteases-GelE and SprE-are responsible for regulating autolysis and the release of high-molecular-weight eDNA, a critical component for the development of E. faecalis biofilms.[GelE and SprE] (Mus musculus) PubMed
3547.
BgsA is a glycosyltransferase synthetizing diglucosyl-diacylglycerol, and is involved in biofilm accumulation. [bgsA] (Mus musculus) PubMed
3548.
Presence of esp gene in Enterococcus faecalis isolates resistant to ampicillin was statistically higher than in susceptible strains, (esp protein, Enterococcus faecalis) (Mus musculus) PubMed
3549.
A unique lysin from the streptococcal bacteriophage C1, termed PlyC, is composed of two separate gene products PlyCA and PlyCB, and defines a previously uncharacterized structural family of cell-wall hydrolases. (PlyC; lysin) (Mus musculus) PubMed
3550.
Results show that Deinococcus radiodurans expresses a DNA polymerase belonging to the X family, PolX, which appears to play an important role in double-stranded DNA break repair [PolX]. (Mus musculus) PubMed
3551.
Crtl gene controls the biosynthesis of red carotenoid including lycopene. [crtl] (Mus musculus) PubMed
3552.
The desaturase activity of DR0861 (crtI) was further confirmed by the assay of enzyme activity in vitro and heterologous expression in Escherichia coli.[crtI] (Mus musculus) PubMed
3553.
Data support the hypothesis that DrRRA contributes to the extreme radioresistance of D. radiodurans through its regulatory role in multiple pathways such as antioxidation and DNA repair pathways: [DrRRA] (Mus musculus) PubMed
3554.
Data show that a recO null mutant exhibited a growth defect and extreme sensitivity to irradiation with gamma rays and UV light, suggesting that DNA repair in this organism occurs mainly via the RecF pathway [RecO] (Mus musculus) PubMed
3555.
Results suggest that while the stable protein core DdrA157 is functional for DNA binding and gamma radiation protection in vitro, the carboxyl terminus is required for important functions in vivo: [DdrA] (Mus musculus) PubMed
3556.
These results suggest a role, either directly or indirectly, for PprI as a general switch to efficiently enhance the DNA repair capability and extreme radioresistance of D. radiodurans via regulation of a series of pathways. (Mus musculus) PubMed
3557.
DR2250 encodes carotenoid 3',4'-desaturase (CrtD), which catalyses the C-3',4'-desaturation of the monocyclic precursor of deinoxanthin but not acyclic carotenoids. [CrtD] (Mus musculus) PubMed
3558.
deinococcal polymerase X is involved in DNA-damage tolerance of D. radiodurans, possibly by contributing to DNA double-strand break repair and base excision repair. [DNA polymerase X/PolX] (Mus musculus) PubMed
3559.
Cobalamin-independent methionine synthase binding sites permit direct interaction of the substrates in a ternary complex. (Cobalamin-independent methionine synthase) (Mus musculus) PubMed
3560.
new intracellular alkaline alpha-amylase identified and characterized to have a remarkably high pH optimum of pH 8.5 and an unusual sensitivity towards both ATP and EDTA.[AmyC] (Mus musculus) PubMed
3561.
Recombinant EstD was found to exhibit significant esterase activity with preference for short acyl chain esters (C4-C8). monomeric enzyme has a molecular mass of 44.5 kDa & optimal activity around 95 degrees C at pH 7.[EstD] (Mus musculus) PubMed
3562.
analysis on the thermostable MutL protein found in Thermotoga maritima MSB8 (MutL) (Mus musculus) PubMed
3563.
Report characterized the first beta-1,2-mannosyltransferase that uses di-myo-inositol phosphate as the mannosyl acceptor. [beta-1,2-mannosyltransferase] (Mus musculus) PubMed
3564.
the replication initiator gene rctB for oriCIIVC is under multiple negative and positive controls; multiple modes of control are expected to reduce fluctuations in the initiator concentration & help maintain chromosome copy number homeostasis [rctB] (Mus musculus) PubMed
3565.
5-Methyl cytosine (m5C) was detected in genomic DNA of the enteric pathogen Vibrio cholerae by HPLC analysis and immunoblotting with m5C-specific antibody. [vchM] (Mus musculus) PubMed
3566.
Study reports that the alternative sigma factor sigma(E) plays a critical role in determining V. cholerae resistance to antimicrobial peptides (AP) and that OmpU is a key determinant of basal sigma(E) expression. [sigmaE or rpoE protein] (Mus musculus) PubMed
3567.
These data suggest that processing of MicX enhances its effectiveness, and that sRNA cleavage is not simply a means to sRNA inactivation and clearance.(MicX) (Mus musculus) PubMed
3568.
These two toxin genes belong to the RTX family and are thought to play a role in pathogenicity. They display hemolytic activity, are involved with biofilm formation and cell adhesion, and contain cadherin domains. [rtxL1, rtxL2] (Mus musculus) PubMed
3569.
vrrA gene is a small non-coding RNA which represses ompA translation and release of outer membrane vesicles. [vrrA] (Mus musculus) PubMed
3570.
TrxA of the host strain is involved in the propagation of the VP3 phage.[TrxA] (Mus musculus) PubMed
3571.
Based on these results, I discuss the potential roles of STRIP in T5 and T6 transcription and in initiating SSV-1 DNA replication. [T5, T6] (Mus musculus) PubMed
3572.
required for aerobic but not for anaerobic growth [Mn-catalase] (Mus musculus) PubMed
3573.
PaaK activity was upregulated during growth on phenylacetate or phenylalanine. [paaK] (Mus musculus) PubMed
3574.
Binding of RNA substrates is mediated by the Hera C-terminal domain, but does not require a previously proposed putative RNase P motif within this domain (Hera). (Mus musculus) PubMed
3575.
The authors identified an ATPase (tRNA-two-thiouridine C, TtuC) required for the 2-thiolation of s(2)T in Thermus thermophilus.[TtuC] (Mus musculus) PubMed
3576.
Heat-resistant RNA-dependent ATPase (Hera) from Thermus thermophilus was overproduced in Escherichia coli and purified to homogeneity for studying the crystal structure.[Hera] (Mus musculus) PubMed
3577.
A novel electron transport system for thermostable CYP175A1 from Thermus thermophilus HB27 (Mus musculus) PubMed
3578.
These results demonstrated that Tomato leaf curl Java virus capsid protein shuttles between the nucleus and cytoplasm, such an activity homolog to bipartite geminivirus BV1 ORF.[capsid protein] (Mus musculus) PubMed
3579.
Results describe the olsB gene, which is required for ornithine lipid biosynthesis [olsB]. (Mus musculus) PubMed
3580.
role in Lipid A biosynthesis related to stress resistance and in alfalfa symbiosis [lpxXL, acpXL] (Mus musculus) PubMed
3581.
role or RirA in regulation of genes involved in global iron metabolism, including Fe-S cluster formation (Mus musculus) PubMed
3582.
identification of the rctA gene present in symbiotic plasmids; rctA gene seems to represent novel but probably widespread regulatory systems controlling the transfer of conjugative elements within the order Rhizobiales [rctA] (Mus musculus) PubMed
3583.
Beta-ketoadipate succinyl-coenzyme A (CoA) transferase activity involved in protocatechuate metabolism in S. meliloti was shown to be encoded by SMb20587 and SMb20588, and these genes have been renamed pcaI and pcaJ, respectively. [PcaI, PcaJ] (Mus musculus) PubMed
3584.
The expression of Lipopolysaccharide sulfotransferase (lpsS) is upregulated in strains that constitutively express the symbiotic regulator SyrA. [LpsS] (Mus musculus) PubMed
3585.
the divalent cation-dependent transcriptional downregulation of lpsS is dependent on the exoR gene, which encodes a global regulator of transcription. (Mus musculus) PubMed
3586.
we propose a model in which the symbiosis regulator CbrA functions as a developmental switch during symbiosis [CbrA] (Mus musculus) PubMed
3587.
Sinorhizobium meliloti hpdA, which encodes the herbicide target 4-hydroxyphenylpyruvate dioxygenase, is positively regulated by HpdR.[HpdR] (Mus musculus) PubMed
3588.
findings show that there are two triose phosphate isomerase encoding genes with different functions; tpiA is hypothesized to be constitutively active in a gluconeogenic role; tpiB is required for erythritol catabolism by an unknown mechanism [TpiA, TpiB] (Mus musculus) PubMed
3589.
We demonstrated that Mur(Fur-like protein) protein binds with high affinity to the promoter region of mntA gene in a manganese-responsive manner. [Mur][MntA] (Mus musculus) PubMed
3590.
We demonstrate that the ExpR/Sin quorum-sensing system controls motility gene expression through the VisN/VisR/Rem relay. [ExpR, Sin] (Mus musculus) PubMed
3591.
Loss of ManX decreased expression of melA-agp and lac, the operons needed for utilization of alpha- and beta-galactosides, slowed growth on diverse carbon sources, and enhanced accumulation of high-molecular-weight succinoglycan.[ManX] (Mus musculus) PubMed
3592.
GtrA and GtrB affect cell growth and effective symbiosis of S. meliloti [GtrA and GtrB] (Mus musculus) PubMed
3593.
The PS-accumulating psd mutant, MAV01, initiated nodule formation much later than the wild type and formed 90% fewer nodules than the wild type.[psd] (Mus musculus) PubMed
3594.
The authors show that the iron-regulated shmR gene encodes an outer membrane protein required for growth on heme.[ShmR] (Mus musculus) PubMed
3595.
The analyses revealed that ExpR is a highly versatile regulator with a unique ability to show different regulatory capabilities in the presence or absence of an autoinducer. New Gene: ExpR (Mus musculus) PubMed
3596.
The authors demonstrate that LpxXL and AcpXL play important but distinct roles in bacteroid development and that LpxXL is essential for the modification of S. meliloti bacteroid lipid A with VLCFAs.[LpxXL & AcpXL] (Mus musculus) PubMed
3597.
EmmA may play a greater role in the overall fitness of S. meliloti both during the free-living stage and in its association with its host. [EmmA] (Mus musculus) PubMed
3598.
analysis of Bmdbt and BmCKIalpha splice variants in Bombyx mori [Bmdbt, also called casein kinase Iepsilon] (Mus musculus) PubMed
3599.
These results suggest that Bm33 (SNF2 global transactivator homologue) is not essential for virus growth in vitro or in vivo, but that it accelerates the time of death of B. mori larvae. [Bm33] (Mus musculus) PubMed
3600.
FP25K is essential for the proper transcriptional regulation and efficient secretion of V-CATH. [FP25K] (Mus musculus) PubMed
3601.
BM61 was a late structure protein localized in nucleus. [BM61] (Mus musculus) PubMed
3602.
Two identical tandem genes rbr3A and rbr3B, which encode the heat shock protein Hsp21, show the transcription pattern of general stress genes (rbr3A, rbr3B). (Mus musculus) PubMed
3603.
Mass spectrometric analysis of purified MccA from Wolinella succinogenes suggests that two of the single cysteine residues are actually part of an unprecedented CX15CH sequence involved in haem c binding.[MccA] (Mus musculus) PubMed
3604.
Ldt(fm) is a novel peptidoglycan cross-linking enzyme for a beta-lactam-resistant transpeptidation pathway [Ldt(fm)] (Mus musculus) PubMed
3605.
E. faecium blood culture-derived isolates harbouring esp had a significantly higher ability to acquire the vanA gene cluster in vitro when compared with esp- isolates [esp] (Mus musculus) PubMed
3606.
Point mutations in penicillin-binding protein 5 (PBP5) and the levels of PBP5 expression were found to be significantly associated with ampicillin resistance. [PBP5] (Mus musculus) PubMed
3607.
study demonstrates that Esp expression on the surface of E. faecium (i) varies consistently between strains, (ii) is growth condition dependent, and (iii) is quantitatively correlated with initial adherence and biofilm formation [esp] (Mus musculus) PubMed
3608.
the C-terminal region of the pbp5 gene was highly polymorphic among the AmpR and AmpS isolates of animal origin; there seemed to be a correlation between specific changes located at positions close to the active site of PBP5 and the ampicillin MIC [pbp5] (Mus musculus) PubMed
3609.
Results showed distinct characteristics in mutation patterns of ermB and ermA. (Mus musculus) PubMed
3610.
The authors show with a rat endocarditis model that TX0082 Deltaacm::cat is highly attenuated versus wild-type TX0082.[Acm in strain TX0082] (Mus musculus) PubMed
3611.
PilA and PilB are two fimbriae proteins. Expression is growth condition- and temperature-dependent. [PilA, PilB] (Mus musculus) PubMed
3612.
E. faecium enterococcal surface protein Esp is not essential for high density colonization of the GI tract by nosocomial strains. [Esp] (Mus musculus) PubMed
3613.
efmA is constitutively expressed under laboratory growth conditions and would contribute to intrinsic resistance against multiple antimicrobial agents in E. faecium FN-1. (Mus musculus) PubMed
3614.
the first crystal structure of a member of the APH(2'') family of aminoglycoside phosphotransferases [Aminoglycoside-2''-phosphotransferase-IIa [APH(2'')-IIa]] (Mus musculus) PubMed
3615.
Our findings suggest that Enterococcal surface protein, Esp also has a role in ampicillin sensitivity. [Esp] (Mus musculus) PubMed
3616.
Esp expression enhanced in vitro binding to bladder and kidney epithelial cells [esp] (Mus musculus) PubMed
3617.
the SgrA and EcbA surface proteins were characterized to gain insight into their function in hospital-acquired E. faecium infections (Mus musculus) PubMed
3618.
RKA1 was upregulated in mycelial cells, indicate that an active PKA pathway promotes yeast-like growth and opposes mycelial development [protein kinase A] (Mus musculus) PubMed
3619.
YlInp1p is a peripheral peroxisomal membrane protein that affects the partitioning of peroxisomes between mother cell and bud in Y. lipolytica. (Mus musculus) PubMed
3620.
we report on the characterization of the Yarrowia lipolytica Ire1 ortholog. Our results show that Sls1, a nucleotide exchange factor for BiP, has important functions in regulating ER stress and the interaction of BiP and Ire1 (Sls1). (Mus musculus) PubMed
3621.
Ind1 facilitates the assembly of Fe-S cofactors and subunits of complex I.[Ind1] (Mus musculus) PubMed
3622.
{Snf7; Rim9; Rim23] YlRim23p is required for the alkaline pH response and interacts with YlSnf7 confirming the link between the Rim and Vps pathways, and deletion of the C-terminal tail of YlRim9p/PalI had no phenotypic effect on ambient pH signalling (Mus musculus) PubMed
3623.
Our data suggest that ornithine decarboxylase (ODC) gene transcription is down-regulated by putrescine, and stimulated by spermidine. [ODC] (Mus musculus) PubMed
3624.
The expression of FBP1 was not repressed by glucose. [FBP1] (Mus musculus) PubMed
3625.
New components of Yarrowia lipolytica Golgi multi-protein complexes containing the alpha-1,6-mannosyltransferases YlMnn9p and YlAnl1p (Mus musculus) PubMed
3626.
reveal an unprecedented role for members of the Pex3 protein family in peroxisome motility and inheritance in addition to their well-established role in peroxisome biogenesis at the endoplasmic reticulum.[Pex3] (Mus musculus) PubMed
3627.
Data show that show that SC3 hydrophobin adopts the amyloid state at the water-PTFE interface:[SC3 hydrophobin] (Mus musculus) PubMed
3628.
CgAUS1 appears to function as a sterol transporter that may contribute to lower azole susceptibility in the presence of serum and to protect C. glabrata against azole toxicity in vivo. [AUS1] (Mus musculus) PubMed
3629.
role for SLT2 and chitin production in the response of C. glabrata to caspofungin. [SLT2] (Mus musculus) PubMed
3630.
Data first demonstrate that CgSNQ2 contributes to the development of CgPDR1-dependent azole resistance in C. glabrata: CgPDR1 and CgSNQ2 (Mus musculus) PubMed
3631.
Cta1 was required for resistance to oxidative stressi and this resistance was dependent on the stress-related transcription factors Yap1p, Skn7p, and Msn4p.[Cta1,Yap1p, Skn7p, Msn2p, and Msn4p] (Mus musculus) PubMed
3632.
Three Epa family members functionally identified as adhesins in Candida glabrata (Epa1, Epa6 and Epa7) bind to ligands containing a terminal galactose residue.[Epa1, Epa6 and Epa7] (Mus musculus) PubMed
3633.
Msn2 regulated general stress response in C. glabrata. [Msn2, Msn4] (Mus musculus) PubMed
3634.
Rif1, Ku70 and Ku80 regulate silencing only a subset of genes at telomeres. [Rif1, Ku70 and Ku80 ] (Mus musculus) PubMed
3635.
decreased susceptibilities of C. glabrata clinical isolates to azole antifungals mainly results from gain-of-function mutations in the gene encoding the CgPdr1p transcription factor [CgPdr1p] (Mus musculus) PubMed
3636.
CgPho4 protein is necessary and sufficient for Pho2-independent gene expression. [PHO4, PHO2] (Mus musculus) PubMed
3637.
Four crystal structures of C. glabrata FMNAT in different complexed forms were determined at 1.20-1.95 A resolutions[FMN adenylyltransferase] (Mus musculus) PubMed
3638.
Data suggest that ascidian cellulose synthase is required for the coordination of the metamorphic events in the trunk and tail in addition to cellulose biosynthesis [cellulose synthase]. (Mus musculus) PubMed
3639.
These findings suggest that functional homologues of both the BH1-3 death effector Bax and the pro-survival Bcl-XL exist in sea squirt Ciona intestinalis, and they control the cell death machinery independent of their heterodimerization.[Bax, Bcl-XL] (Mus musculus) PubMed
3640.
Ci-p65, was transiently induced upon fertilization via T4 and found to exert its anti-apoptotic role in test cells nuclei as well as in a reconstituted cell system. (Ci-65) (Mus musculus) PubMed
3641.
The C3a receptor molecule involved in C. intestinalis C3a-mediated chemotaxis has been cloned and characterized and its expression profile analyzed. [C3aR, complement 3a receptor] (Mus musculus) PubMed
3642.
role in embryonic myogenesis of the MRF gene; we conclude MRF is required for larval tail muscle development and that an MRF-dependent myogenic regulatory network probably existed in the ancestor of tunicates and vertebrates [myogenic regulatory factor] (Mus musculus) PubMed
3643.
The full-length htt mRNA of Ciona intestinalis was sequenced, characterized and compared with other chordate species. HTT. (Mus musculus) PubMed
3644.
Ciona intestinalis APEX transcripts are clearly detectable in oocytes and embryos until the larva stage, but not in spermatozoa.(APEX) (Mus musculus) PubMed
3645.
the ascidian genome contains a single ASIC gene that gives rise to two splice forms; proton-independent mechanisms mediate the effects of ASIC in vivo. [ASIC] (Mus musculus) PubMed
3646.
Potential modulator of sperm-activating and sperm-attracting factor (SAAF) release from the egg. (Valosin-containing protein/p97) (Mus musculus) PubMed
3647.
C. intestinalis Mras orthologue (Ci-Mras) was expressed in the neural complex of the ascidian juveniles after metamorphosis.[Mras] (Mus musculus) PubMed
3648.
Misexpression of Lhx3b is sufficient to induce ectopic Mesp activation in cells expressing Tbx6b. Injection of antisense morpholino oligonucleotides showed that the Lhx3b isoform is required for endogenous Mesp expression.(Tbx6) (Mus musculus) PubMed
3649.
Ciona intestinalis alternative oxidase expression appears to offer promise as a wide-spectrum therapeutic tool in oxidative phosphorylation disorders. (Mus musculus) PubMed
3650.
Suggest that NO, specifically generated by nNOS, mediates sympathetic cardiac-cardiovascular responses through its action in the rostral ventrolateral medulla. (Mus musculus) PubMed
3651.
Neither the hyperpermeability in response to simultaneous stimulation of VEGFR-1 and VEGFR-2 nor VEGFR-1-mediated severe inflammation was associated with VEGF-E(NZ7)/PlGF-induced angiogenesis. (VEGF-E(NZ7)) (Mus musculus) PubMed
3652.
In this study, we show that both orf virus strains (NZ2 and NZ7)express equivalent levels of the viral VEGF variants and during infection of sheep skin induce comparable levels of vascularization, edema, epidermal rete ridge and scab formation. [VEGF] (Mus musculus) PubMed
3653.
ORFV structural proteins 10 kDa and F1L fused to FlAG peptide were displayed on surface of infectious particles, whereas ORF110-FLAG localized to the Golgi of infected cells and egress from the cells. [10kda, F1L, ORF-110] (Mus musculus) PubMed
3654.
Pseudorabies Viral envelope glycoprotein D (gD) was found to be necessary and sufficient for the induction of varicosities. (Mus musculus) PubMed
3655.
extreme C terminus of (p)UL36 fulfills an essential role in pseudorabies virus replication, while a large internal portion of the C-terminal half of the protein is dispensable for replication in cell culture[(p)UL36] (Mus musculus) PubMed
3656.
role of the 28-kDa amino-terminal product (nsp1) of the gene 1 polyprotein during replication of the coronavirus murine hepatitis virus (MHV) in cell culture. (nsp1 protein) (Mus musculus) PubMed
3657.
the replicase gene of murine coronavirus JHM strain plays a role in hepatitis [replicase] (Mus musculus) PubMed
3658.
Low doses of nsp1 mutant MHV elicited potent cytotoxic T cell responses and protected mice against virus challenge. (Mus musculus) PubMed
3659.
matrix protein behaves like an integral membrane protein although its primary structure suggests it to be a peripheral membrane protein[matrix protein] (Mus musculus) PubMed
3660.
The beta-ribbon structure folds over the peptide binding cleft and clearly contributes to substrate recognition by 3C protease (3C protease). (Mus musculus) PubMed
3661.
results demonstrate that, in contrast to the betaG-betaH loop RGD motif, the second RGD sequence in the capsid protein 1D of NAM/307/98 does not function as a ligand for receptor binding in BHK-21 cells [capsid 1D] (Mus musculus) PubMed
3662.
Molecular cloning and expression of two outer membrane proteins, BpsOmp38 (from Burkholderia pseudomallei) and BthOmp38 (from Burkholderia thailandensis)[omp38] (Mus musculus) PubMed
3663.
The type IVA pilin-encoding gene, pilA, is essential for microcolony development by B. pseudomallei and thus optimum association with eukaryotic cells. (Mus musculus) PubMed
3664.
A comprehensive biophysical analysis of the dynamic conformational behavior of the truncated monomeric needle subunit proteins MxiH(Delta5), BsaL(Delta5), and PrgI(Delta5), is presented.[BsaL] (Mus musculus) PubMed
3665.
The full length (933 bp) gene of bipD, a member of TTSS cluster of Burkholderia pseudomallei, was isolated by PCR amplification from B. pseudomallei DNA and cloned into pGEX 4T-1 [BipD] (Mus musculus) PubMed
3666.
a B. pseudomallei strain with mutation in the bsaQ gene, encoding a structural component of the type III secretion system (T3SS), was constructed. (Mus musculus) PubMed
3667.
study identified the RpoS regulon; used Hidden Markov Model for prediction of RpoS-dependent promoters in 51 genes encoding 63 down-regulated proteins in rpoS(-) strain & defined the promoters, which were classified into 3 main groups [RpoS] (Mus musculus) PubMed
Here the authors show that isocitrate lyase is a persistence factor for B. pseudomallei, and inhibiting the activity of this enzyme during experimental chronic B. pseudomallei lung infection forces the infection into an acute state.[isocitrate lyase] (Mus musculus) PubMed
3670.
Rgt1 binds to the RAG1 promoter in a glucose-dependent manner and represses RAG1 expression. (Rgt1) (Mus musculus) PubMed
3671.
biochemical analysis and comparison of KlNde1p and KlNde2p [external alternative dehydrogenases KlNde1p and KlNde2p] (Mus musculus) PubMed
3672.
unusual structure, so far found only in telomerase RNA, provides an essential and conserved telomerase-specific function[telomerase RNA] (Mus musculus) PubMed
study shows that Sck1 coordinates glucose import and glycolysis in K. lactis and that Rag8 controls this transcription factor by transcriptional and post-translational regulations [Sck1, Rag8] (Mus musculus) PubMed
3675.
YND1 is isolated and characterized as an endopyrase that enhances the secretion of the recombinant human serum albumin and glucoamylase employed as reporters, and suppresses cell wall phenotypes and glycosylation defects. [YND1] (Mus musculus) PubMed
3676.
The membrane-associated protein KNQ1, has a new unexpected role in iron homeostasis on which dithiothreitol tolerance may depend. [KNQ1] (Mus musculus) PubMed
3677.
We identified a 15-bp element responsible for the transcriptional repression of mitochodnrial alcohol dehydrogenase (ADH3) by ethanol. [ADH3] (Mus musculus) PubMed
3678.
From these results, it can be deduced that the K. lactis MATa cell produces the homolog of the S. cerevisiaealpha-pheromone, whereas the MATalpha cell produces the a-pheromone. [MATa, MATalpha] (Mus musculus) PubMed
3679.
Transcription factor gene GCR1 is a suppressor of the fermentation regulator Rag3. [GCR1,Rag3] (Mus musculus) PubMed
3680.
A novel glucokinase, Glk1, phosphorylates glucose, but fails to act on fructose as a sugar substrate.[Glk1] (Mus musculus) PubMed
3681.
Double and triple deletion mutants of KlWSC1, KlWSC2/3 and KlMID2 genes show severe cell wall integrity defects. indicating overlapping functions.[KlWSC1, KlWSC2/3 and KlMID2 in strain KB6-2C] (Mus musculus) PubMed
3682.
Two regulatory regions which contain the consensuses for KlGcr1p and KlMig1p binding are functional in the KlHEM1 promoter. (KlHEM1) (Mus musculus) PubMed
3683.
A stable anticodon stem and the anticodon loop are the minimal requirements for cleavage by gamma-toxin (gamma toxin). (Mus musculus) PubMed
3684.
The 5' arm of K. lactis telomerase RNA (TER) has critical roles in telomerase function, which may be linked to the function of Est3 [TER, Est3] (Mus musculus) PubMed
3685.
Glycerol diminishes KlICL1 expression and a single carbon source responsive element (CSRE) sequence is both necessary and sufficient to mediate this regulation.[ICL1] (Mus musculus) PubMed
3686.
The LAC1 protein of K. lactis is the enzyme that plays a crucial role in the synthesis of glucosylceramide. [LAC1] (Mus musculus) PubMed
3687.
analysis of the molecular basis of Gal4p recognition by Gal80p [Gal4, Gal80] (Mus musculus) PubMed
3688.
Regulation of PGS1 expression by myo-inositol and choline was not mediated at the transcriptional level. [PGS1] (Mus musculus) PubMed
3689.
Disruption of the KlPCL1 gene neither impaired sporulation nor affected growth. [PCL1] (Mus musculus) PubMed
3690.
Hap1 limits glucose uptake by repressing the expression of the glucose transporter gene RAG1. [Hap1, Rag1] (Mus musculus) PubMed
3691.
These results demonstrate that Pdr1p is involved in Kluyveromyces lactis multidrug resistance and is required for cell's tolerance to various cytotoxic compounds.[Pdr1p in strain PM6-7A] (Mus musculus) PubMed
3692.
Structure-activity relationships in Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease (Mus musculus) PubMed
3693.
a protein homologous to transposases, called alpha3, was essential for mating type switch in Kluyveromyces lactis [alpha3] (Mus musculus) PubMed
3694.
three different peptides belonging to the tandem repeat region of StPrP-2 from Takifugu rubripes have been considered; the coordination modes and conformations of their complexes with Cu(II) have been investigated [StPrP] (Mus musculus) PubMed
3695.
The primary structures of a CXC chemokine (CXCL8) and two CXC receptors (CXCR) have been characterized in fugu, Takifugu rubripes [cxcL8, CXCR!, CXCR2] (Mus musculus) PubMed
3696.
TLR3 and TLR22 link the IFN-inducing pathway via TICAM-1 [TICAM1][TLR3] (Mus musculus) PubMed
3697.
Reduction of PmHHK1 expression produces significant changes in morphogenesis (including polarized growth), sporulation and cell wall composition. [histidine kinase/PmHHK1/Penicillium marneffei GX1005] (Mus musculus) PubMed
3698.
full-length VP7 gene of Indian bluetongue virus (BTV) serotype 23 was sequenced and compared with prototype strains of BTV reported from different countries. (Mus musculus) PubMed
3699.
gL from rhesus lymphocryptovirus plays role in the recruitment of gB in Epstein-Barr virus infected B-cell membrane fusion. [gL] (Mus musculus) PubMed
3700.
The catalytic domain of glucuronoyl esterase from Hypocrea jecorina has been characterized; this is the first enzyme with glucoronoyl esterase activity to be crystallized. (glucuronoyl esterase) (Mus musculus) PubMed
3701.
Lim1, despite its function in sulphur metabolite repression, responds both to light as well as sulphur- and carbon source[LIM1, E3 ubiquitin ligase protein] (Mus musculus) PubMed
3702.
The data presented demonstrate that Aes1 and other homologous microbial proteins may represent a new family of esterases for lignocellulose biodegradation.[Aes1] (Mus musculus) PubMed
3703.
GNA3 regulated cellulase gene expression by positively modulating its stimulation by light. [GNA3, cellulase] (Mus musculus) PubMed
3704.
For Hypocrea jecorina grown on cellulose, the G-protein alpha subunit (GNA1) has a light-dependent role in regulation of cellulase and hydrophobin gene transcription. GNA1 also has a role in regulation of growth and stress tolerance [GNA1] (Mus musculus) PubMed
3705.
findings strongly suggest the involvement of a protease recognition pattern at the cleavage site of the fusion protein as a determinant of virulence [F protein] (Mus musculus) PubMed
3706.
findings show that two proteins, encoded by the un-spliced ORF from genomic segment 7 (s7ORF1) and the larger ORF from segment 8 (s8ORF2), are involved in modulation of the type I interferon (IFN) response. [s7ORF1, s8ORF2] (Mus musculus) PubMed
3707.
EspG modulates enteropathogen's host cytoskeleton function involving transient microtubule destruction and actin polymerization [EspG] (Mus musculus) PubMed
3708.
NleB is an essential virulence determinant of attaching and effacing pathogen Citrobacter rodentium (Mus musculus) PubMed
3709.
significant loss of mitochondrial respiratory function in the infected intestinal epithelium; Map was implicated in the disruption of epithelial barrier function [Map protein] (Mus musculus) PubMed
3710.
EspI modulates the virulence of attaching and effacing pathogens by binding host PDZ-domain proteins. (Mus musculus) PubMed
3711.
This is the first report to describe the molecular mechanism by which an environmental chemical stimulates transcription of virulence-associated genes of an enteric pathogen through an AraC/XlyS-like activator,RegA.[RegA] (Mus musculus) PubMed
3712.
RegA is a global regulator of virulence in C. rodentium which activates factors that are required for intestinal colonization. (Mus musculus) PubMed
3713.
In conclusion, RpoS is important for the stress response and is required for full virulence in C. rodentium. (Mus musculus) PubMed
3714.
These results suggest that EspT modulates the host cell cytoskeleton through coactivation of Rac-1 and Cdc42 by a distinct mechanism.[EspT] (Mus musculus) PubMed
3715.
PhoPQ regulates croP expression and the presence of CroP at the outer membrane. CroP contributes to the protection of the OM from antimicrobial peptide damage by actively degrading alpha-helical AMPs. [CroP] (Mus musculus) PubMed
3716.
The presence of bicarbonate relieves the autoinhibition of RegA activity by its N-terminal arm.[RegA] (Mus musculus) PubMed
3717.
Our data suggest that HCR2 is involved in HCS and identification of the gene may contribute to understanding the mechanisms for production of a hypercoagulable state of several critical clinical disorders. [hypercoagulability related gene-2 (HCR2)] (Mus musculus) PubMed
3718.
assembly of early viral chromatin requires both the association of SET/TAF-1beta and the release of protein VII.[protein VII] (Mus musculus) PubMed
3719.
We identified a novel interaction between E4 ORF3 and TIF1alpha [E4 ORF3] (Mus musculus) PubMed
3720.
UXP is a previously unrecognized protein derived from a novel late l-strand transcription unit with suggested function of DNA replication or RNA transcription.[UXP] (Mus musculus) PubMed
3721.
describes the mechanism of FX binding to Ad5 and demonstrates the critical role of hexon for virus infection of hepatocytes in vivo. [hexon capsid proteins] (Mus musculus) PubMed
3722.
An NF-kappa B-independent pathway is defined through which the E1A oncogene of human adenovirus sensitizes mouse and human cells to apoptosis by enhancement of caspase-2-mediated mitochondrial injury. [early region 1A oncogene; E1A oncogene] (Mus musculus) PubMed
3723.
PML was found to be important for E1A-induced suppression of EGFR and subsequent killing of head and neck squamous cell carcinoma cells suggesting a novel pathway involving PML and p73 in the regulation of EGFR expression.[E1A] (Mus musculus) PubMed
3724.
ORF3 protein of porcine circovirus (PCV) type 2 plays an important role in PCV2 viral pathogenesis via its apoptotic activity.[ORF3] (Mus musculus) PubMed
3725.
Results show that the PCV2 ORF3 protein specifically interacts with pPirh2 and inhibits its stabilization; this may lead to increasing p53 expression, resulting in apoptosis.[ORF3 protein] (Mus musculus) PubMed
3726.
The ORF3 mutant virus did not cause any observable disease or perturbation of the lymphocyte count in the inoculated piglets and elicited an efficient immune response. (Mus musculus) PubMed
3727.
The DNA binding potential and the significant region that confers the nuclear localization of the Rep protein were characterized. (Mus musculus) PubMed
3728.
The class III chitin synthase gene contains 2,739 bp and encodes a protein with 913 aa. [chitin synthase ] (Mus musculus) PubMed
3729.
Blotched snakehead virus (BSNV) is a member of the Birnaviridae family that requires a virally encoded protease known as VP4 in order to process its polyprotein into viral capsid protein precursors (protease VP4) (Mus musculus) PubMed
3730.
Ssk2 is a critical interface connecting the two-component system and the Pbs2-Hog1 MAPK pathway in C. neoformans [Ssk2, Pbs2, Hog1] (Mus musculus) PubMed
3731.
Sxi1alpha and Sxi2a control sexual development in a homeodomain-dependent fashion using DNA-binding sequences different from those defined previously for fungi. [Sxi1alpha;Sxi2a] (Mus musculus) PubMed
3732.
An essential role for acetate permease A (AcpA)in mediated acetate transport (AcpA). (Mus musculus) PubMed
3733.
Taken together, these results suggest that ArfA participates in hyphal growth through the secretory system.[ArfA] (Mus musculus) PubMed
3734.
CrzA and SltA are both capable of binding DNA and SltA acts positively on transcription of the Ena1p-like Na+ pump gene enaA and negatively on transcription of the putative vacuolar Ca2+/H+ exchanger gene vcxA (CrzA and SltA). (Mus musculus) PubMed
3735.
study identified the VelB/VeA/LaeA complex connecting light-responding developmental regulation & control of secondary metabolism; VeA interacts with VelB; VeA bridges VelB to the nuclear master regulator of secondary metabolism, LaeA [VelB, VeA, LaeA] (Mus musculus) PubMed
3736.
The results strongly support the view that during growth, FadA/SfaD/GpgA G protein signaling inhibits proteinase production via both Galpha and Gbetagamma subunits.[FadA, SfaD, GpgA] (Mus musculus) PubMed
3737.
Apoptosis-Inducing Factor-like mitochondrial oxidoreductase transcription is induced by farnesol and is improtant for decreasing the effects of farnesol and reactive oxygen species. [aifA] (Mus musculus) PubMed
3738.
analysis of the fungal phytochrome FphA from Aspergillus nidulans [FphA] (Mus musculus) PubMed
3739.
ugmADelta strains had compact colonial growth, which was associated with substantially delayed and abnormal conidiation.[ugmA in strain A1149] (Mus musculus) PubMed
3740.
Disruption of aatB resulted in a reduced penicillin titre.[[AatB] (Mus musculus) PubMed
3741.
FlbE is an upstream developmental activator which functions in close association with putative transcription factor FlbB. [FlbE] (Mus musculus) PubMed
3742.
Overexpression of imeB results in efficient sexual differentiation independently of light and repression of asexual development. ImeB is also needed for expression of the sterigmatocystin gene cluster. [ImeB] (Mus musculus) PubMed
3743.
ChiB is necessary for the DeltaflbA-induced autolysis. [ChiB] (Mus musculus) PubMed
3744.
This is believed to be the first report demonstrating the presence of soluble alpha1,2-mannosidase from the glycosyl hydrolases family 47 in a cytosolic compartment of the cell. [alpha1,2-mannosidase] (Mus musculus) PubMed
3745.
CaPTC8 plays a role in stress responses and is required for the yeast-hyphal transition, and the CaPTC8-related genes are evolutionarily conserved.[CaPTC8] (Mus musculus) PubMed
3746.
RHB1 and TSC2 are involved in nitrogen starvation-induced filamentation. [Tsc2] (Mus musculus) PubMed
3747.
Ena21 is a sodium ion transporter that increases salt tolerance. [Ena21] (Mus musculus) PubMed
3748.
Rfx2p regulates DNA damage responses, morphogenesis, and virulence. [RFX2] (Mus musculus) PubMed
3749.
Histological examination confirmed that the vps21Delta and ypt72Delta mutants are deficient in hyphal growth in vivo.[ypt72] (Mus musculus) PubMed
3750.
Msb2 is involved in the transmission of the signal toward Cek1 mediated by the Cdc42 GTPase. [Msb2] (Mus musculus) PubMed
3751.
an analysis of sequences of the large subunit which reliably finds specificity-enhancing mutations and ranks them according to the probability of success. (Mus musculus) PubMed
3752.
The control mechanism of the unique light-responsive groE expression is highly diversified in cyanobacteria [groESL1] (Mus musculus) PubMed
3753.
48 of the 108 copies of the 5S rRNA genes are located 3' of tRNA genes (5S rRNA). (Mus musculus) PubMed
3754.
crystal structure of TT1751 at 2.0 angstrom resolution [TT1751] (Mus musculus) PubMed
3755.
We report here the sat1 gene encoding L-serine O-acetyltransferase[SAT] of an extreme thermophile, Thermus thermophilus HB8.[sat1] = L-serine O-acetyltransferase, Thermus thermophilus HB8] (Mus musculus) PubMed
3756.
TT1662 from Thermus thermophilus HB8 is a member of the alpha/beta hydrolase fold enzymes (Mus musculus) PubMed
3757.
The crystal structure of a novel polyprenyl pyrophosphate binding protein, TT1927b, from Thermus thermophilus HB8, complexed with its ligand (TT1927b). (Mus musculus) PubMed
3758.
X-ray crystallographic structure of a purine/pyrimidine phosphoribosyltransferase-related protein from the thermophilic bacterium, Thermus thermophilus HB8 [APRTase] (Mus musculus) PubMed
3759.
The hydrophilic domain (peripheral arm) of the proton-translocating NADH:quinone oxidoreductase (complex I) from the thermophilic organism Thermus thermophilus HB8 has been purified and characterized[Nqo15] (Mus musculus) PubMed
3760.
A structural insight into the DNA recognition by this protein. [AT-rich DNA-binding protein; p25] (Mus musculus) PubMed
3761.
Hypothetical protein TTHA0281 is speculated to be involved in RNA metabolism, including RNA binding and cleavage. (Mus musculus) PubMed
3762.
Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8 (Mus musculus) PubMed
3763.
latter loop further changes its conformation upon binding of 4-hydroxyphenylacetate 3-monooxygenase and obstructs the active site from the bulk solvent[4-hydroxyphenylacetate 3-monooxygenase ] (Mus musculus) PubMed
3764.
The crystal structure of PaaG from Thermus thermophilus HB8 was determined at a resolution of 1.85 A. PaaG consists of three identical subunits related by local three-fold symmetry.[PaaG] (Mus musculus) PubMed
3765.
To further examine V. fischeri lipid A and its symbiotic function, we identified two paralogs of htrB (designated htrB1 and htrB2) and an msbB gene in strain ES114 and demonstrated that these genes encode lipid A secondary acyltransferases. [htrB, msbB] (Mus musculus) PubMed
3766.
An antimicrobial agent hypersensitive strain of Escherichia coli harboring murA from V. fischeri exhibited a high fosfomycin resistance phenotype, with minimum inhibitory concentration of 3,000 microg/ml.[MurA in strain VF107] (Mus musculus) PubMed
3767.
identification of a serine-aspartate repeat protein that binds collagen. [SrdI] (Mus musculus) PubMed
3768.
Systems pivotal for the organism's defense against photooxidative stress are strongly dependent on glutathione and are recognized by RpoH(II) in R. sphaeroides[RpoH(II)] (Mus musculus) PubMed
3769.
X-ray structure of the L protein (BchL) of the dark-operative protochlorophyllide reductase has been determined with bound MgADP to 1.6 A resolution [bchL] (Mus musculus) PubMed
3770.
Results indicate that the lipid membrane acts to accelerate proton uptake by the membrane-bound proton transporter cytochrome c oxidase of Rhodobacter sphaeroides.(cytochrome c oxidase / cytochrome aa3) (Mus musculus) PubMed
3771.
Results suggests the 17(3)-ester group of the bacteriochlorophyll P(A) to be involved in covalent interaction with the I(L177) photosynthetic reaction center subunit H (photosynthetic reaction center subunit H). (Mus musculus) PubMed
3772.
Hetero-oligomeric FleQ/FleT activated flagellar promoters through a conserved binding site. [FleQ, FleT] (Mus musculus) PubMed
3773.
The Raman results reported here demonstrate that R481 residue in cytochrome c oxidase plays a critical role in supporting efficient proton pumping, by holding the heme groups in a proper environment.[cytochrome c oxidase] (Mus musculus) PubMed
3774.
results indicate that AppA17-133 and AppA1-126 contain Trp104 in distinct alternate conformations in solution and that light absorption by the flavin causes partial movement/uncovering of Trp104 (AppA). (Mus musculus) PubMed
3775.
The 74-kDa MDH is involved in tricarboxylic acid cycle, while the 148-kDa MDH takes part in the citramalate pathway/ [MDH] (Mus musculus) PubMed
3776.
effect of ionic strength on the second-order electron transfer rate constant, k(2), between cyt c(2) and native or mutant RCs[cytc2] (Mus musculus) PubMed
3777.
T. fusca cutinases adopt an alpha/beta-hydrolase fold that exhibits both similarities and variations from the fungal cutinase structure (Mus musculus) PubMed
3778.
Expression patterns of cel5A and cel5B, two endoglucanase encoding genes were compared; the relative expression levels of cel5A were always higher than those of cel5B.(cel5A)(cel5B) (Mus musculus) PubMed
3779.
D274A Cel6B and its catalytic domain bound more tightly to both bacterial microcrystalline cellulose and swollen cellulose, respectively, than the wild-type Cel6B[exocellulase Cel6B] (Mus musculus) PubMed
3780.
CYP709C1 is a sub-terminal hydroxylase of long chain fatty acid in plants (Mus musculus) PubMed
3781.
DPE1-e exhibits disproportionating activity in vitro by cleaving maltotriose to produce glucose as well as being able to use maltoheptaose as the donor for the addition of glucans to the outer chains of glycogen and amylopectin. (Mus musculus) PubMed
3782.
Transcripts were detectable in the developing palea, but not in other floral organs, suggesting that WFL may play a novel role in developing palea in the wheat floret. (WFL = wheat FLO/LFY) (Mus musculus) PubMed
3783.
Wheat genome contains three similar genes of translation initiation factors 5A, eIF5a1 eIF5a2 and eIF5a3. [eIF5a1 eIF5a2 and eIF5a3] (Mus musculus) PubMed
3784.
SUT1B/D functions to transport Sucrose into the scutellum from the endosperm early in germination and later transports maltose. [SUT1B] & [SUT1D] (Mus musculus) PubMed
3785.
The roles of glutamine synthetase and NADH-dependent glutamate dehydrogenase in the accumulation of proline was determined in leaves of wheat seedlings exposed to salt stress. [GS & NADH-GDH] (Mus musculus) PubMed
3786.
findings suggest reductions in populations of Diuraphis noxia fed Dnx plants are related to the expression of sequences involved in defensive chemical production, cellular transport, and exocytosis. [Dnx] (Mus musculus) PubMed
3787.
The STS Xhor2kv and SSR Xgdm33 are two flanking markers that are tightly linked to H22 at genetic distances of 0.3 and 1.0 cM, respectively.(H22) (Mus musculus) PubMed
3788.
isolation and characterization of a cDNA clone encoding RanBP from wheat; it is expressed ubiquitously in roots, leaves and stems, with a similar abundance in these tissue [RanBP1] (Mus musculus) PubMed
3789.
Qualitative mapping of Fhb2 in wheat provides tightly linked markers that can reduce linkage drag associated with marker assisted selection of Fhb2 and aid the pyramiding of different resistance loci for wheat improvement. (Mus musculus) PubMed
3790.
cloning of Gpc-B1, a QTL associated with increased grain protein, zinc & iron content; ancestral wild wheat allele encodes NAM-B1 that accelerates aging & increases nutrient mobilization to developing grain; modern wheat has nonfunctional allele [NAM-B1] (Mus musculus) PubMed
3791.
This work is the first report of mapping Psy genes and supports the role of Psy1-1 in elevated levels of endosperm colour in durum wheat.[Phytoene synthase] (Mus musculus) PubMed
3792.
high molecular weight glutenin subunit allele 1Bx23 in common wheat (Mus musculus) PubMed
3793.
The LR1RGA1 encoding a CC-NBS-leucine-rich repeat type of protein, represents a very good candidate for the leaf rust resistance gene, Lr1 (LR1RGA1). (Mus musculus) PubMed
3794.
There are conserved cis-acting elements and trans-acting factors that enable the TaPT2 promoter to be regulated in a tissue-specific and Pi-dependent fashion in both monocots and dicots. [PT2] (Mus musculus) PubMed
3795.
Lr21-mediated signaling pathways require the wheat homologs of RAR1, SGT1, and HSP90[RAR1] (Mus musculus) PubMed
3796.
data provide molecular evidence that TaVRN1 may have pleiotropic effects in various processes such as control of axillary bud growth, transition to flowering and development of floral organs [TaVRN1] (Mus musculus) PubMed
3797.
Mutations within the Viviparous-1B gene are linked to abscisic acid sensitivity and resistance to pre-harvest sprouting. (Mus musculus) PubMed
3798.
characterization of three new wheat receptor-like kinase (RLK) genes (TaRLK-R1, 2 and 3); transcript levels of TaRLK-R1, 2 and 3 increased during the hypersensitive reaction to stripe rust fungus [RLK-R1, RLK-R2, RLK-R3] (Mus musculus) PubMed
3799.
The results are consistent with the hypothesis that chloroplast EF-Tu plays a functional role in heat tolerance by acting as a molecular chaperone.[EF-Tu] (Mus musculus) PubMed
3800.
SR07 fragment may play an important role in the water regulation of the plant. [SR07] (Mus musculus) PubMed
3801.
tin3 gene was mapped to a 324-kb region spanned by two overlapping bacterial artificial chromosomes (BACs) of rice chromosome arm 1L [tin3] (Mus musculus) PubMed
3802.
A cDNA (TaCM, caffeic acid 3-O-methyltransferase was identified from wheat and it was found to be expressed constitutively in stem, leaf and root tissues. (Mus musculus) PubMed
3803.
The first evidence of FNR (isolated from spinach and from wheat) interaction directly with a model membrane without the mediation of any additional protein, is presented.[FNR] (Mus musculus) PubMed
3804.
results imply that stage-specific transcription of TaBx3 and TaBx4 is not controlled by global sequence similarity of their promoters but by some essential cis-elements [Bx3 & Bx4] (Mus musculus) PubMed
3805.
These data demonstrate that eIFiso4F can kinetically compete with eIF4F for VPg binding.[eIF4F, eIFiso4F] (Mus musculus) PubMed
3806.
These results support the hypothesis that allelic differences in PSY-1 and at least one additional gene in the distal region of the long arm of homoeologous group 7L are associated with differences in grain yellow pigment content.[PSY-1] (Mus musculus) PubMed
3807.
SOS1 expressed in yeast cells lacking major endogenous sodium transporters restored salt tolerance and enhanced sodium/hydrogen exchange at the plasma membrane. (SOS1) (Mus musculus) PubMed
3808.
a cDNA clone encoding wheat CRT was successfully isolated and the results suggest that TaCRT is involved in the plant response to drought stress, indicating a potential in the transgenic improvements of plant water-stress [CRT] (Mus musculus) PubMed
3809.
The populations of wild emmer wheat showed a wide range of diversity in dimeric alpha-amylase inhibitors, both between and within populations (WDAI-3 (Mus musculus) PubMed
3810.
These observations implied that TaF(A)d is under mitochondrial retrograde regulation in the anthers of cytoplasmic male sterility plants with timopheevii cytoplasm.[TaF(A)] (Mus musculus) PubMed
3811.
Pm36, a gene conferring powdery mildew resistance, has been mapped to Triticum chromosome 5. [Pm36] (Mus musculus) PubMed
3812.
The RIP (tritin) activity and RIP-RALyase-mediated cleavage of SRD in the cytoplasmic ribosome were induced at the late stage of senescence of wheat coleoptiles.(RALyase) (Mus musculus) PubMed
3813.
results provide evidence that there have been only few evolutionary changes in Hv- and TaGAMYB; this confirms the close relationship between these species and also highlights the functional importance of this transcription factor [GAMYB] (Mus musculus) PubMed
3814.
Expression of the cold-Regulated genes, Wcs120, Wcor410, and Wcor14 was differentially regulated in the leaf and crown tissues.[Wcor14] (Mus musculus) PubMed
3815.
genomic locations of Lr48 and Lr49 genes [Lr48; Lr49] (Mus musculus) PubMed
3816.
TaCHSL1 is an anther-specific chalcone synthase-like gene which is highly expressed in the tapetum. [TaCHSL1] (Mus musculus) PubMed
3817.
LrZH84 is mapped as a new leaf rust resistance gene. (Mus musculus) PubMed
3818.
Four loci responsible for the activity of disulfide reductase were identified on chromosomes 4A, 5D, 6A, and7D. [disulfide reductase] (Mus musculus) PubMed
3819.
In order to reveal the mechanism by which 1By16 and 1Bx13 creates high quality, their open reading frames were amplified from common wheat Atlas66 and Jimai 20.[1Bx13, 1By16] (Mus musculus) PubMed
3820.
The mitochondrial gene orf260cra causes pistillody in alloplasmic wheat. [orf260cra] (Mus musculus) PubMed
3821.
These results suggested that TaAIDFa encodes a CRT/DRE element-binding factor that might be involved in multiple abiotic stress signal transduction pathways.[AIDFa] (Mus musculus) PubMed
3822.
The powdery mildew resistance gene Pm23 is relocated on chromosome 2AL. [Pm23] (Mus musculus) PubMed
3823.
Ph1 suppresses homoeologous chromosome interactions by regulating the level of TaASY1 expression during meiosis. [Ph1] (Mus musculus) PubMed
3824.
Structural and expressional divergence of genes encoding O-methyltransferase in wheat.[TaOMT4, TaOMT5]. (Mus musculus) PubMed
3825.
YrC591 is a novel stripe rust resistance gene in wheat. (Mus musculus) PubMed
3826.
Lr34 is a leaf rust resistance gene that helps upregulate genes associated with defense and stress-related proteins, secondary metabolism enzymes, and transcriptional regulation and cellular-signaling proteins. [Lr34] (Mus musculus) PubMed
3827.
MATE1 contributes to aluminum resistance via the citrate efflux pathway. [TaMATE1] (Mus musculus) PubMed
3828.
sdi1 expression was specifically induced in leaf and root tissues in response to sulphate deficiency. [sdi1] (Mus musculus) PubMed
3829.
Two unexpressed 1By genes from Triticum aesitvum L.ssp.yunnanese AS332 and T. aesitvum ssp.tibetanum AS908 were respectively cloned and characterized.[Glu-B1] (Mus musculus) PubMed
3830.
Large differences exist in relative expression levels of alpha-gliadins from the homoeologous Gli-2 loci among wheat genotypes. [Gli-2] (Mus musculus) PubMed
3831.
Upregulation of VRN1 during the light period was followed by the accumulation of FLOWERING LOCUS T. [VRN1] (Mus musculus) PubMed
3832.
the gene Lr34 confers resistance to multiple fungal pathogens; findings show the LR34 protein resembles ABC transporters of the pleiotropic drug resistance subfamily; alleles of Lr34 conferring resistance or susceptibility differ by 3 polymorphisms [Lr34] (Mus musculus) PubMed
3833.
After refolding and purification, TaGluD with 1 unit of beta-1,3-glucanase showed antifungal activity in vitro against Rhizoctonia solani, Rhizoctonia cerealis, Phytophthora capsici and Alternaria longipes.[GluD] (Mus musculus) PubMed
3834.
TaCPS3 is responsible for gibberellin biosynthesis, while TaCPS1 and TaCPS2 are possible functional homologs of diterpene cyclase genes OsCPS2 and OsCPS4 involved in phytoalexin biosynthesis in rice [CPS1; CPS2; CPS3] (Mus musculus) PubMed
3835.
Pea enation mosaic virus RNA 2 cap-independent translation elements binds eIF4F and its eIF4E subunit with high affinity.[eIF4F] (Mus musculus) PubMed
3836.
Comparative mapping of the soft glume (sog) gene of diploid Triticum monococcum L. and tenacious glume (Tg) gene of hexaploid T. aestivum L, is reported.[sog, Tg] (Mus musculus) PubMed
3837.
CM gene expression, enzyme activity, and protein content were associated with the lodging-resistant phenotype in wheat. [CM] (Mus musculus) PubMed
3838.
Pho1 enzyme activity levels were shown to increase throughout the period of starch synthesis [Pho1, starch phosphorylase] (Mus musculus) PubMed
3839.
Glo-3A wheat globulin is the gene for wheat protein WP5212. [Glo-3A] (Mus musculus) PubMed
3840.
Results describe wheatwin1 ribonuclease activity in three mutants with altered active sites [wheatwin1]. (Mus musculus) PubMed
3841.
Recognition of ToxA via Tsn1 triggers transcriptional reprogramming events similar to those reported for avirulence-resistance gene interactions.[Tsn1] (Mus musculus) PubMed
3842.
Study genetically mapped a TaPHT1.2 transporter, TaPHT1.2-D1, on the long arm of chromosome 4D using a recombinant inbred line derived from Xiaoyan 54 and Jing 411, and isolated a1,302 bp fragment of the TaPHT1.2-D1 promoter from Xiaoyan 54.[PHT1.2] (Mus musculus) PubMed
3843.
interaction of residues Leu292 of TAXI-IA and Pro294 of TAXI-IIA with the -2 glycon subsite of the xylanase is shown to be critical for both inhibition strength and specificity.[xylanase inhibitor XI-II} (Mus musculus) PubMed
3844.
The objective of the present study was to characterize IgE epitopes of Tri a 14 and to compare them with those of Pru p 3.[Tri a 14] (Mus musculus) PubMed
3845.
TM20 transmembrane protein has a polarized distribution within the cell in the most differentiated stages of development [TM20] (Mus musculus) PubMed
3846.
Maize mutants with a Mu-element insertion in UDPGDH-A or UDPGDH-B were isolated (udpgdh-A1 and udpgdh-B1 respectively) and studied for changes in wall polysaccharide biosynthesis.[UDPGDH-A; UDPGDH-B] (Mus musculus) PubMed
3847.
functional differentiation of maize LFNR isoenzymes, LFNR1, LFNR2, and LFNR3 [LFNR1, 2, and 3] (Mus musculus) PubMed
3848.
Conserved and divergent aspects of ZmSCR, the SCARECROW ortholog in Z. mays, are reported.[SCR] (Mus musculus) PubMed
3849.
Dwarf8 could be involved in maize climatic adaptation through diversifying selection for flowering time [Dwarf8] (Mus musculus) PubMed
3850.
SsChlI protein variants containing the substitutions identified in the dominant Oy1 maize alleles lack activity necessary for magnesium chelation and confer a semi-dominant phenotype via competitive inhibition of wild-type SsChlI.[SsChlI] (Mus musculus) PubMed
3851.
In the present study, reactions of maize (Zea mays) (cytokinin dehydrogenase) (CKX) with five different substrates (N6-isopentenyladenine, trans-zeatin, kinetin, p-topolin and N-methyl-isopentenyladenine) were studied. (Mus musculus) PubMed
3852.
quantitated the distribution of the three maize SUS isoforms across several maize tissues, analyzed their membrane association and investigated novel phosphorylation sites [Sh1; Sus2] (Mus musculus) PubMed
3853.
analysis of secondary structure and processes of oligomerization of 19 kDa alpha-zein [Z19] (Mus musculus) PubMed
3854.
Xcl1 is associated with L1 division patterns, hormonal pathways, and meristem maintenance. (Mus musculus) PubMed
3855.
Expression pattern of ZmPIN1a and ZmPIN1b in the SAM, tassel, and ear of maize [ZmPIN1a and ZmPIN1b] (Mus musculus) PubMed
3856.
the mop1 RNA-dependent RNA polymerase is required to maintain a threshold level of repeat RNA, which functions in trans to establish and maintain the heritable chromatin states associated with paramutation [mop1] (Mus musculus) PubMed
3857.
1) Molecular cloning, genomic characterization, and functional expression of the XylT gene is reported. [XylT] 2) Molecular cloning, genomic characterization, and functional expression of the FucT gene is reported.[FucT] (Mus musculus) PubMed
3858.
The ZmTCRR-1 protein codes for a member of the type-A response regulator class of proteins and is expressed exclusively in the endosperm transfer-cell layer 8-14 days after pollination, when transfer-cell differentiation is most active. (Mus musculus) PubMed
3859.
The presence of Zea m 1 in the pollen coat and wall suggests that Zea m 1 may play a potential role in pollen germination on the stigma. [Zea m 1 (beta-expansin 1)] (Mus musculus) PubMed
3860.
A model of expansin action in which EXPB1 facilitates the local movement and stress relaxation of arabinoxylan-cellulose networks within the wall by noncovalent rearrangement of its target, is proposed.[EXPB1] (Mus musculus) PubMed
3861.
A major quantitative trait locus affecting root traits and leaf abscisic acid concentration was identified in Z. mays and named root-ABA1.[ABA1] (Mus musculus) PubMed
3862.
TDY1 acts as a sugar sensor to regulate an inducible sugar export pathway as leaves develop under high light conditions. [TDY1] (Mus musculus) PubMed
3863.
The conservation of a paralogous gene sequence encoding a cytidine deaminase gene over 4.5 million years suggests that Helitrons could add functional gene sequences to new chromosomal positions and thereby create new haplotypes.[cytidine deaminase] (Mus musculus) PubMed
3864.
The roles of two cytosolic maize glutamine synthetase isoenzymes (GS1), products of the Gln1-3 and Gln1-4 genes, were investigated by examining the impact of knockout mutations on kernel yield.[gs1-3] (Mus musculus) PubMed
3865.
See2beta has an important role in nitrogenuse and resource allocation under nitrogen limited conditions, and a minor but significant function in the later stages of senescence.[See2] (Mus musculus) PubMed
3866.
EMP4 is necessary to regulate the correct expression of a small subset of mitochondrial transcripts in the endosperm. [EMP4] (Mus musculus) PubMed
3867.
Recessive y9 alleles condition accumulation of 9,15,9'-tri-cis-zeta-carotene in dark tissues, such as roots and etiolated leaves. [y9] (Mus musculus) PubMed
3868.
results support a model whereby Tdy1 acts in the veins to promote Suc export[Tdy1] (Mus musculus) PubMed
3869.
Random mutagenesis and expression of the maize endosperm AGPase show that the two AGPase subunits are equally predisposed to enzyme activity-altering amino acid changes when expressed in one environment with a single complementary subunit.[AGPase] (Mus musculus) PubMed
3870.
Ask1 and Ask2 were isolated, cloned, and mapped. [2 genes, Ask1 & Ask2] (Mus musculus) PubMed
3871.
Cytokinin-binding protein (CBP70) is a transcript elongation factor or a modulator of elongation factor activity specifically mediating a cytokinin-dependent regulation of transcription. (Mus musculus) PubMed
3872.
NDC80 is a constitutive feature of the central kinetochore [NDC80] (Mus musculus) PubMed
3873.
Findings suggest that ZmDWF4 may be an ortholog gene of Arabidopsis DWF4 and responsible for brassinolide biosynthesis in maize: ZmDWF4 (Mus musculus) PubMed
3874.
Thiamine biosynthesis gene thi3 from maize Zea mays has been identified through cloning and sequencing of cDNA and heterologous overexpression of the encoded protein, THI3, in Escherichia coli. (Mus musculus) PubMed
3875.
A maize clone (thermotolerance 6; TTO6) that seemed to confer elevated heat tolerance in comparison to control cells.[TTO6] (Mus musculus) PubMed
3876.
The results are consistent with the hypothesis that chloroplast EF-Tu plays a functional role in heat tolerance by acting as a molecular chaperone.[EF-Tu, rca] (Mus musculus) PubMed
3877.
CBL4 functions in the salt stress-elicited calcium signaling and thus in the tolerance to salinity. [CBL4] (Mus musculus) PubMed
3878.
The cloning and characterization of the novel maize phosphoethanolamine N-methyltransferase gene (ZmPEAMT1) was reported (ZmPEAMT1) (Mus musculus) PubMed
3879.
These findings describe a function for the bHLH domain of R in linking transcriptional regulation with chromatin functions by the recruitment of an EMSY-related factor.[R protein] (Mus musculus) PubMed
3880.
findings show that rmr1 encodes a novel Snf2 protein that affects both small RNA accumulation and cytosine methylation of a proximal transposon fragment at the Pl1-Rhoades allele [rmr1] (Mus musculus) PubMed
3881.
ZmLOX3-mediated pathway may act as a root-specific suppressor of all three major defense signaling pathways to channel plant energy into growth processes, but is required for normal levels of resistance against nematodes.[ZmLOX3] (Mus musculus) PubMed
3882.
findings show that variation at the lycopene epsilon cyclase locus alters flux down alpha-carotene versus beta-carotene branches of the carotenoid pathway [lycopene epsilon cyclase] (Mus musculus) PubMed
3883.
study proposes a model whereby TDY1 and TDY2 function together in a single genetic pathway, possibly in homo- and heteromeric complexes, to promote carbon export from leaves. [Tdy1, Tdy2] (Mus musculus) PubMed
3884.
The RIK protein may be involved in the maintenance of an inactive chromatin state of knox and possibly other genes in nonmeristematic tissues. (Mus musculus) PubMed
3885.
Analysis of allele frequencies in a landrace collection supports a key role of Vgt1 in maize altilatitudinal adaptation.[Vgt1] (Mus musculus) PubMed
SDH activity may represent an adaptation to the high-sugar/low-oxygen environment of the endosperm[Iditol 2-Dehydrogenase ] (Mus musculus) PubMed
3888.
heat tolerance of wheat, and possibly other crop plants, can be improved by modulating expression of plastidal EF-Tu and/or by selection of genotypes with increased endogenous levels of this protein[ EF-Tu ] (Mus musculus) PubMed
3889.
ZmLsi1 is an influx transporter of Si, which is responsible for the transport of Si from the external solution to the root cells and that ZmLsi6 mainly functions as a Si transporter for xylem unloading. [ZmLsi1; ZmLsi6] (Mus musculus) PubMed
data suggest that light induction of acetylation on promoter elements of the C4-Pepc gene is controlled by regulating Histone Acetyltransferases activity (C4-Pepc). (Mus musculus) PubMed
3892.
ATG8 is lipidated during development and in response to nutrient limitations, indicating that autophagy plays a key role in nutrient remobilization. [ATG8] (Mus musculus) PubMed
3893.
Alignment of respective chromosomal regions of these species via conserved genes allow identification of the pedigree of prolamin gene copies in space and time (Mus musculus) PubMed
3894.
The loss of mop1 or ts1 function results in increased mRNA levels for several members of the SBP-box gene family.[mop1, ts1] (Mus musculus) PubMed
3895.
Glycolate Oxidase 1 mutants grow normally under high CO2 conditions, but CO2 assimilation rapidly and linearly diminishes in high light and high O2. [GO1] (Mus musculus) PubMed
3896.
The proportion of known miRNAs is higher in the mop1-1 mutant relative to wild type and 24-nt siRNA levels are proportionally reduced.(mop1) (Mus musculus) PubMed
3897.
RNA-dependent RNA polymerase is required for enhancer-mediated transcriptional silencing associated with paramutation at the maize p1 gene (Mus musculus) PubMed
3898.
TDY1 functions in carbon partitioning by promoting phloem loading. [TDY1] (Mus musculus) PubMed
3899.
Suppressor of sessile spikelets1 functions in the ra1 branch of the ramosa pathway controlling meristem determinacy. [Sos1] (Mus musculus) PubMed
3900.
These data indicate that the poor penetrance and expressivity of Ufo1-induced phenotypes is caused by mosaicism of methylation, and progressive mitotic hypomethylation leads to improved meiotic heritability of the mutant phenotype.[Ufo1] (Mus musculus) PubMed
3901.
Maize AKR4C7 could utilize dl-glyceraldehyde and some pentoses as substrates... Polyclonal antisera raised against AKR4C7 recognized at least three AR-like polypeptides in maize kernels, consistent with the presence of a small gene family. [AKR4C7] (Mus musculus) PubMed
3902.
The interactions of a mutant maize line (lox3-4, in which ZmLOX3 is disrupted) with the mycotoxigenic seed-infecting fungi Aspergillus flavus and Aspergillus nidulans, was tested.[ZmLOX3] (Mus musculus) PubMed
3903.
BIF2 phosphorylates ZmPIN1a and regulates its subcellular localization in vivo. [ZmPIN1a] (Mus musculus) PubMed
3904.
kn1 and td1 function in a pathway to maintain meristem homeostasis but their products may interact with different partners during development.[thick tassel dwarf1 (td1)] (Mus musculus) PubMed
3905.
DCD1 and ADD1 function in preprophase band formation. [DCD1; ADD1] (Mus musculus) PubMed
3906.
findings implicate PAN1 in the transmission of an extrinsic signal that polarizes asymmetric subsidiary mother cell divisions toward guard mother cells [PAN1] (Mus musculus) PubMed
3907.
Lysine-81 and threonine-82 within the I72-T82 region of Glu1 are important for BGAF binding.[BGAF] (Mus musculus) PubMed
3908.
findings showed that the largest subunit of the presumed maize RNA Polymerase IV is involved in paramutation as well as normal maize development [rmr6, RPD1] (Mus musculus) PubMed
3909.
Differential expression of LcyB and LcyE mediates carotenoid accumulation and composition. LCYE generates a number of unusual carotenoids when LCYB activity is eliminated. [LycB; lycopene beta-cyclase] (Mus musculus) PubMed
3910.
The consecutive action of the two starch-related dikinases, the glucan, water dikinase and the phosphoglucan, water dikinase, was studied.[PWD, GWD] (Mus musculus) PubMed
3911.
Recombinant plant defensin corn 1 (Pdc1) inhibits the growth of Fusarium graminearum. The secondary structure of the recombinant protein was determined. (PDC1; corn EST sequence PCO081743, GenBank accession no. AY109292) (Mus musculus) PubMed
3912.
The molecular masses of ICL1, ICL2 , and ICL isoforms determined by gel filtration are 164, 207, and 208 kDa, respectively. [ICL1, ICL2] (Mus musculus) PubMed
3913.
Two related maize proteins, ZmMRPI-1 and ZmMRPI-2 belonging to the C(2)H(2) zinc finger protein family, which interact with ZmMRP-1 and modulate its activity on transfer cell specific promoters, were idenetifed.[BETL1, ZmMRP-1] (Mus musculus) PubMed
3914.
three-dimensional structure of an m144/beta2-microglobulin (beta2m) complex at 1.9A resolution [m144] (Mus musculus) PubMed
3915.
the ER environment restricts access of m4/gp34 to K(b); although m4/gp34-K(b) complexes could form when m4 was carried either by MCMV or the adenovirus vector, they were only efficiently exported from the ER in MCMV-infected cells [GP34] (Mus musculus) PubMed
3916.
IE3 protein, expressed preferentially in glial cells, may play the main role in acute infection. [IE3] (Mus musculus) PubMed
3917.
Mouse cytomegalovirus (MCMV) molecule fcr-1 promotes a rapid down-regulation of NKG2D ligands murine UL16-binding protein like transcript (MULT)-1 and H60 from the cell surface. (Mus musculus) PubMed
3918.
findings show that products of the m142 and m143 genes of murine cytomegalovirus together bind dsRNA [m142, m143] (Mus musculus) PubMed
3919.
These results indicate that m142 and m143 are both required for inhibition of the PKR-mediated host antiviral response.[m142, m143] (Mus musculus) PubMed
3920.
The crystal structure of the cysteine protease domain of murine cytomegalovirus M48 (M48(USP)) in a complex with a ubiquitin (Ub)-based suicide substrate, is reported. (Mus musculus) PubMed
3921.
The downregulation of NKG2D ligands by MCMV makes only a small contribution to the impact of m152/gp40 on CTL lysis and only for a small subset of CTL. (Mus musculus) PubMed
3922.
structural analysis of the murine cytomegalovirus major histocompatibility complex class I-like glycoprotein, m153 (Mus musculus) PubMed
3923.
Our results suggest that neither ORF is essential for virus replication but m29.1 is important for optimal viral growth in vitro and in vivo.[m29.1] (Mus musculus) PubMed
3924.
N- and C-terminal regions of M33 as well as known 7TMR signature motifs in transmembrane (TM) II and TM III to determine the impact on cell surface expression, constitutive signaling, and in vivo phenotype were probed.(M33) (Mus musculus) PubMed
3925.
These results consolidate the role of m38.5 as a viral mitochondrion-localized inhibitor of apoptosis and its functional similarity to the human cytomegalovirus UL37x1 gene product.[m38.5] (Mus musculus) PubMed
3926.
m157 mutations are predicted to alter the conformation of a putative m157 interface with Ly49H, one that relies on the position of a critical alpha0 helix of m157[ m157 protein] (Mus musculus) PubMed
3927.
Data show that murine cytomegalovirus arrests cells in G(1) and can also replicate in G(2) cells, due to the cell cycle-independent expression of MCMV immediate-early gene 3. (Mus musculus) PubMed
3928.
m38.5 associates with Bax, recruits it to mitochondria, and blocks Bax-mediated but not Bak-mediated mitochondrial outer membrane permeabilization. (Mus musculus) PubMed
3929.
The viral pm142-pm143 multimer interacts with PKR and causes its sequestration in cellular compartments where it is unable to shut off translation and repress viral replication.[pm142 & pm143] (Mus musculus) PubMed
3930.
The activating Ly49P receptor recognizes cells infected with mouse cytomegalovirus (MCMV) by a process that requires the presence of H2-D(k) and the MCMV m04 protein.[m04] (Mus musculus) PubMed
3931.
M33 contributes to the efficient establishment or maintenance of long-term latent murine cytomegalovirus infection. [M33] (Mus musculus) PubMed
3932.
M140 indirectly influences capsid formation in differentiated macrophages by regulating the stability of viral structural proteins.[M140] (Mus musculus) PubMed
3933.
M33 stimulates CREB transcriptional activity in a phospholipase C-beta and protein kinase C (PKC)-dependent manner. [M33] (Mus musculus) PubMed
3934.
CpcT is a new phycocyanobilin lyase that specifically attaches phycocyanobilin to Cys-153 of the phycocyanin beta-subunit[CPCT] (Mus musculus) PubMed
3935.
it is proposed that CcmR (and its associated regulon) represents a specialization for species inhabiting environments subject to fluctuating inorganic carbon concentrations [ccmR] (Mus musculus) PubMed
3936.
Thus, CpcM is the methyltransferase that modifies the amide nitrogen of Asn71/72 of CpcB, ApcB, and ApcF. (Mus musculus) PubMed
3937.
LjBGD2 and LjBGD4 preferentially hydrolyzed rhodiocyanoside A and lotaustralin, whereas linamarin was only slowly hydrolyzed [BGD2, BGD4] (Mus musculus) PubMed
3938.
Nodulin26-like Intrinsic Proteins (NIPs) LjNIP5;1 and LjNIP6;1 from Lotus japonicus are bi-directional As(III) channels [Nodulin26-like Intrinsic Proteins (NIPs) LjNIP5;1 and LjNIP6;1 ] (Mus musculus) PubMed
3939.
Differences in the C-terminal domains of PCS1 and PCS3 are responsible for their distinct expression levels or stabilities in heterologous systems and patterns of metal activation. [PCS3] (Mus musculus) PubMed
3940.
LjHb1 overexpression enhances symbiotic nitrogen fixation activity by removing NO as an inhibitor of nitrogenase. [LjHb1] (Mus musculus) PubMed
3941.
Overexpressing LjCLE-RS1 and -RS2 inhibits nodulation, and suppression depends on HAR1. LjCLE-RS2 expression is strongly up-regulated in roots by nitrate addition. [LjCLE-RS1; LjCLE-RS2] (Mus musculus) PubMed
3942.
LjSLY1 plays a negative role in nodule formation and overexpression enhances the level of gibberellin signaling. [Sly1] (Mus musculus) PubMed
3943.
Formation and progression of infection threads into the root cortex were significantly impaired in nap1 and pir1 mutants due to disturbed actin cytoskeleton organization. [nap1;pir1] (Mus musculus) PubMed
3944.
The brush mutant of Lotus japonicus exhibits a temperature-dependent impairment in nodule, root, and shoot development.[Brush] (Mus musculus) PubMed
3945.
The isolation and characterization of a hypernodulating mutant of L. japonicus named too much love is reported.[tml] (Mus musculus) PubMed
3946.
The molecular and biochemical characterization of parvulin-type PPIase family members annotated as LjPar1, LjPar2, and LjPar3 are presented. [3 genes] (Mus musculus) PubMed
3947.
LjNAS2 was expressed only in nodules, but LjNAS1 was expressed mainly in leaves, stems, and cotyledons[Nicotianamine synthase genes: Nas1 and Nas2] (Mus musculus) PubMed
3948.
LjINV1 is crucial to whole plant development, but is not essential for nodule formation or function. [LjINV1] (Mus musculus) PubMed
3949.
The crystal structure of the 3-chlorocatechol 1,2-dioxygenase from the Gram-positive bacterium Rhodococcus opacus (erythropolis) 1CP, specialized in the aerobic biodegradation of 3-chloro- and methyl-substituted catechols, has been solved. (Mus musculus) PubMed
3950.
Atf1 disruption mutant exhibited triacylglycerols leaky phenotype and accumulated 50 % less fatty acids than the wild-type. [Atf1] (Mus musculus) PubMed
3951.
X-ray crystallography of the the N1 neuraminidase of the H5N1 avian virus [neuraminidase] (Mus musculus) PubMed
3952.
ACP binding to human epithelial cell integrins appears to contribute to GBS internalization within epithelial cells. [ACP] (Mus musculus) PubMed
3953.
A transcription-factor binding motif (TTT-N(6)-ATAT)is required for full ACP expression. [ACP] (Mus musculus) PubMed
3954.
Pip protein, a proline iminopeptidase gene is upregulated in cabbage by a LuxR homologue and is essential for pathogenicity of Xanthomonas campestris pv. campestris. [Pip, LuxR] (Mus musculus) PubMed
3955.
Overexpression of the clp gene in Xcc wild-type strain 8004 enhanced the production of XpsE as well as endoglucanase and extracellular polysaccharide (EPS).[Clp, xpsE] (Mus musculus) PubMed
3956.
The pghAxc genes was identified to encode functional polygalacturonases and could be efficiently induced in planta,and were required for the full virulence of X. campestris pv. campestris to Arabidopsis. (Mus musculus) PubMed
3957.
The optimum pH and temperature of purified est were 8.0 and 52 degrees C. [Est] (Mus musculus) PubMed
3958.
VP1U of HBoV has sPLA2-like enzymatic activity, and these residues are crucial for its sPLA2-like activity. (Mus musculus) PubMed
3959.
Regulation of virB by RyhB (iron responsive small RNA molecule) implicates iron as an environmental factor contributing to the complex regulation of Shigella virulence determinants. [RyhB, VirB] (Mus musculus) PubMed
3960.
The heme ATP binding cassette (ABC) transporter, ShuUV, of Shigella dysenteriae has been incorporated into proteoliposomes and functionally characterized: [ShuUV] (Mus musculus) PubMed
3961.
Nonfunctional clyA gene was inactivated either by insertion mutation or frameshift mutation in Shigella strains. (Mus musculus) PubMed
3962.
The TonB-dependent haem outer membrane transporter ShuA of Shigella dysenteriae bound to heavy atoms was crystallized in several crystallization conditions using detergents.[ShuA] (Mus musculus) PubMed
3963.
Evidence that a calcium-dependent protein kinase, CDPK3, has an important function in regulating motility of the ookinete in the mosquito midgut (CDPK3). (Mus musculus) PubMed
3964.
Expression during ookinete development of genes encoding actin, MyoA, and MyoB, was studied and MyoA is only present in fully mature ookinetes, whilst the other two proteins are additionally expressed in gametocytes and zygotes.[Myosin B] (Mus musculus) PubMed
3965.
we report four new mutations (Y268N, Y268C, L271V and K272R), all in the Qo(2) domain of the cytochrome b gene associated with resistance to atovaquone. [Cytochrome b] (Mus musculus) PubMed
3966.
a conserved protein HAP2 required for gamete fusion (Mus musculus) PubMed
3967.
findings show that the rodent malaria parasite gene Plasmodium berghei GENERATIVE CELL SPECIFIC 1 (PbGCS1) plays a central role in its gametic interaction; PbGCS1 knockout parasites show male sterility, resulting in unsuccessful fertilization [GCS1] (Mus musculus) PubMed
3968.
PbSR is synthesized in macrogametocytes, gets targeted to the crystalloids of developing ookinetes and is involved in crystalloid formation.[PbSR] (Mus musculus) PubMed
3969.
PbROM1 functions in the invasive stages of parasite development.[rhomboid 1 protease] (Mus musculus) PubMed
3970.
LISP1-deficient liver-stage parasites do not rupture the membrane of the PV and remain trapped inside hepatocytes.[LISP1] (Mus musculus) PubMed
3971.
PI3K activity is poised to regulate both adenylyl cyclase activation and adaptation, thereby providing a link to ensure the proper balance of counteracting signals required to maintain optimal chemoresponsiveness [adenylyl cyclase] (Mus musculus) PubMed
3972.
Results suggest that Trix is specifically involved in a Rho GTPase-signaling pathway that is required for regulation of the actin cytoskeleton during exocytosis [Trix]. (Mus musculus) PubMed
3973.
Enlazin has roles in cell mechanics and adhesion, and these roles seem to be differentially significant for cytokinesis, depending on the genetic background. (Mus musculus) PubMed
3974.
identification of a novel gene,Trishanku(triA), by random insertional mutagenesis. TriA is a Broad complex Tramtrack bric-a-brac domain-containing protein,expressed during the late G2 phase of cell cycle and in presumptive spore (prespore (psp)) cells. (Mus musculus) PubMed
3975.
These results indicate that partial copies of dutA may act upstream of Dd-STATa to regulate tyrosine phosphorylation by an unknown mechanism [STATa]. (Mus musculus) PubMed
3976.
Results identify a novel vesicle-associated receptor tyrosine kinase-like protein, VSK3, in Dictyostelium discoideum, and demonstrate how VSK3 is involved in phagosome maturation. (Mus musculus) PubMed
3977.
O2-sensor model of prolyl 4-hydroxylase function was provided in an organism that lacks the canonical HIFalpha transcriptional factor subunit substrate. (Prolyl 4-hydroxylase-1) (Mus musculus) PubMed
3978.
Poly(ADP-ribose) polymerase inhibition has no deleterious effect on D. discoideum development under oxidative stress (poly(ADP-ribose) polymerase). (Mus musculus) PubMed
3979.
These results indicate that Dictyostelium G alpha subunit specificity is not limited to receptor coupling and that G alpha subunit sequences outside of the carboxyl terminus are important for cell movement and developmental processes.[G alpha] (Mus musculus) PubMed
3980.
Inactivation of the iplA gene, the only gene encoding an inositol 1,4,5-trisphosphate receptor (IP3R) in this organism, prevented autophagic cell death.[iplA] (Mus musculus) PubMed
3981.
hssA gene, whose expression is known to be G-box-binding-factor-dependent and which was specific to prestalk A (pstA) cells is isolated (Mus musculus) PubMed
3982.
polyketide synthases in Dictyostelium discoideum have roles in biosynthesis of the differentiation regulating factor 4-methyl-5-pentylbenzene-1,3-diol [DiPKS1, DiPKS37] (Mus musculus) PubMed
3983.
Vacuole membrane protein 1 is an endoplasmic reticulum protein required for organelle biogenesis, protein secretion, and development [vmp1] (Mus musculus) PubMed
3984.
Dictyostelium discoideum cells secrete CfaD, a protein that is similar to cathepsin proteases (Mus musculus) PubMed
3985.
Dictyostelium DPYK3 negatively regulates STATc during development in response to DIF-1 signaling.[DPYK3] (Mus musculus) PubMed
3986.
sibA and sibC are both expressed in vegetative Dictyostelium cells, but the expression of sibC is repressed when cellular adhesion decreases. [SibA, sibC] (Mus musculus) PubMed
3987.
A structurally dynamic model for nucleotide- and actin-induced closure of the actin-binding cleft of myosin, based on site-directed spin labeling and electron paramagnetic resonance (EPR) in Dictyostelium myosin II, is presented.[Myosin II] (Mus musculus) PubMed
3988.
Dictyostelium CblA protein regulates STAT signalling via a tyrosine phosphatase [CblA] (Mus musculus) PubMed
3989.
The identification of homolog of Saccharomyces cerevisiae RPB4 in D. discoideum was reported. (Mus musculus) PubMed
3990.
Cyclase associated protein (CAP) acts at multiple crossroads in Dictyostelium discoideum AX2 and links signaling pathways to the actin cytoskeleton either by physical interaction with cytoskeletal components or through gene expression regulation [CAP] (Mus musculus) PubMed
In wild-type slugs, the expL7 promoter was activated in the anterior tip region, but downrgulated in Dd-STATa-null slugs [ExpL7] (Mus musculus) PubMed
3993.
Altered morphogenesis and the cell-sorting defect of rapGAP3(-) cells may result in reduced directional movement of the mutant cells to the apex of the mound.[RapGap3] (Mus musculus) PubMed
3994.
Kif9 maintains a connection between the microtubule-organizing center and nucleus during interphase and Kif6 is essential for viability. [Kif6, Kif9] (Mus musculus) PubMed
3995.
Expression of the C-terminal fragment from the endogenous 34-kDa actin-binding protein of Dictyostelium discoideum leads to the formation of actin inclusions in vivo. [actin binding protein] (Mus musculus) PubMed
3996.
Reg is localized to the nucleus and is present in growing as well as starving Dictyostelium cells. [Reg] (Mus musculus) PubMed
3997.
CenB knockout cells exhibited aberrant nuclear architecture, characterized by enlarged and deformed nuclei and loss of centrosome-nucleus anchoring. [CenB] (Mus musculus) PubMed
3998.
PTEN is a mechanosensing signal transducer for myosin II localization in Dictyostelium cells (Mus musculus) PubMed
3999.
MhcA localizes to the posterior cell cortex and provides the contractile force for translocation of the cell body. [mhcA] (Mus musculus) PubMed
4000.
Purified recombinant ArnT protein was shown to be highly alpha-helical as determined by circular dichroism analysis. (L-Ara4N transferase protein ArnT) (Mus musculus) PubMed
4001.
Production of recombinant SplB and SplC proteases in Escherichia coli, together with structural and functional characterization of the purified enzymes.[splb, splc] (Mus musculus) PubMed
4002.
Inactivation of SarA in 8325-4 increases repression of Hla and depends on reduced expression of SarS, whereas in strain V8, inactivation of SarA decreases repressor activity and, therefore, enhances Hla transcription. [SarA, Hla, SarS] (Mus musculus) PubMed
4003.
These results suggest that the cvfB gene product contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways.[cvfB] (Mus musculus) PubMed
4004.
The data indicate that the expression of rot transcription is significantly repressed only by SarA. [SarA] (Mus musculus) PubMed
4005.
These results indicate that svrA does not play a role in Staphylococcus aureus infections via an agr-mediated pathway.[svrA] (Mus musculus) PubMed
4006.
It was concluded that the fibrillar nature of SasG explains its ability to mask binding of S. aureus microbial surface components recognizing adhesive matrix molecules to their ligands and to promote formation of biofilm.[SasG] (Mus musculus) PubMed
4007.
Complementation studies show that a putative ribitol phosphate polymerase, TarL, catalyzes both the addition of the priming ribitol phosphate onto the linkage unit and the subsequent polymerization of the polyribitol chain.[TarL] (Mus musculus) PubMed
4008.
Ebh might contribute to structural homeostasis by forming a bridge between the cell-wall and cytoplasmic membrane to avoid plasmolysis under hyperosmotic condition.(Ebh) (Mus musculus) PubMed
4009.
This is the first report of the direct observation of an Ebh structure containing a large number of repeating units, although structures containing one, two, or four repeating units have been reported. (Ebh) (Mus musculus) PubMed
4010.
LigA was found to be essential in vitro and in vivo and TarI was found to be essential in vitro but not in vivo. {ligA, TarI] (Mus musculus) PubMed
4011.
The results indicate that SarZ may be an important regulator governing the dissemination phase of S. aureus infections, as it promotes toxin expression while repressing factors required for biofilm formation. (Mus musculus) PubMed
4012.
These results show that rbf is an activator of biofilm formation in different strains of S. aureus, although the degree of activation varies among strains.[Rbf] (Mus musculus) PubMed
4013.
This study shows that SasG-A domain contributes to intercellular autoaggregation by homo-oligomerization, and that may facilitate the adherence to host-tissues in the infection of S. aureus.(SasG) (Mus musculus) PubMed
4014.
Inactivation of gdpS results in an alteration in the production of a range of virulence factors, such as serine and cysteine proteases, fibrinogen-binding proteins, and, specifically, protein A (Spa), a major surface protein of S. aureus.[GdpS] (Mus musculus) PubMed
4015.
analysis of Staphylococcus aureus AgrD residues required for autoinducing peptide biosynthesis [AgrD] (Mus musculus) PubMed
4016.
Our results are consistent with a model wherein rbf represses synthesis of icaR, which in turn results in derepression of icaADBC and increased PNAG production; rbf controls expression of an unknown factor(s) that represses icaR [rbf] (Mus musculus) PubMed
4017.
gARID1 is an important transactivator in regulation of the Giardia cwp1 gene, which is key to Giardia differentiation into cysts [gARID1 and cwp1] (Mus musculus) PubMed
4018.
These results suggest that G. lamblia possesses phospholipases, PLA A1 and PLA A2 isoforms that may be soluble or associated with membranes. [PLA A1, PLA A2] (Mus musculus) PubMed
4019.
The full length variant-specific surface antigen gene, vsp752, from the isolate of G. lamblia has the common characteristics with other previously identified VSPs. [vsp752] (Mus musculus) PubMed
4020.
The glOTC crystal contains one protein molecule in the asymmetric unit and the crystallographic 3-fold symmetry generates a trimeric structure, consistent with the association state measured in solution (vide supra). [OTC] (Mus musculus) PubMed
4021.
Using a reverse genetics approach, the report demonstrate that the tryptophan aminotransferase Tam1 catalyses pigment biosynthesis by conversion of tryptophan into indolepyruvate [Tam1] (Mus musculus) PubMed
4022.
Study reports the identification and characterization of the Cys(2)His(2)-type zinc finger protein Mzr1 that functions as a transcriptional activator during host colonization. [Mzr1] (Mus musculus) PubMed
4023.
demonstrate that Khd4 recognizes the sequence AUACCC in vivo via its tandem KH domains 3 and 4.[Khd4] (Mus musculus) PubMed
4024.
This is the first reported Entamoeba PAK member that contains a N-terminal pleckstrin homology domain and a highly conserved Cdc42/Rac interacting binding domain. [PAK2] (Mus musculus) PubMed
4025.
These findings clearly suggest that the 29-kDa protein of E. histolytica has a role in both survival of trophozoites in the presence of reactive oxygen species and pathogenesis of amoebiasis. (Mus musculus) PubMed
4026.
These data indicate that the two Rab7 isotypes play distinct but co-ordinated roles in lysosome and phagosome biogenesis.[Rab7A, Rab7B] (Mus musculus) PubMed
4027.
These results indicate that in addition to cytoskeletal association, EhLimA may also associate with lipid rafts in the parasite plasma membrane (EhLimA). (Mus musculus) PubMed
4028.
KERP1 was also seen to be a virulence marker as trophozoites affected in kerp1 expression by an antisense strategy were unable to form liver abscesses.[KERP1] (Mus musculus) PubMed
4029.
Downregulation of EhMLBP using antisense technology resulted in trophozoites with impaired growth and cytopathic activity, indicating that EhMLBP is an essential protein.[MLBP] (Mus musculus) PubMed
4030.
CrzA is an important downstream effector of calcineurin that controls morphology in A. fumigatus. [CrzA] (Mus musculus) PubMed
4031.
Ace2 is a factor that is essential for normal conidiation, cell wall architecture and pigment production. [Ace2] (Mus musculus) PubMed
4032.
These results showe that the mitochondrial copy number is reduced in the DeltacalA mutant strain, and the mutant has increased alternative oxidase (aoxA) mRNA accumulation and activity. .[CalA] (Mus musculus) PubMed
4033.
The LmjF01.0030 gene of Leishmania major Friedlin, annotated as 'MCAK-like', was confirmed as a kinesin with an internally located motor domain and termed LmjKIN13-1.(LmjKIN13-1) (Mus musculus) PubMed
4034.
Genome sequence of Leishmania major revealed two genes coding for two isoforms of SHMT the short form was found in the cytosol while the long one was found in an organelle that has hallmarks of the parasite mitochondrion. [Serine hydroxymethyltransferase] (Mus musculus) PubMed
4035.
Detailed kinetic studies comparing TDPX1 and TryP1 showed that both enzymes obey saturation ping-pong kinetics and both enzymes show high affinity for tryparedoxin and broad substrate specificity for hydroperoxides (TDPX1 and TryP1). (Mus musculus) PubMed
4036.
These data support the hypothesis that ISP2 and 3 of L. major target host serine peptidases and influence the early stages of infection of the mammalian host.[ISP2 & ISP3] (Mus musculus) PubMed
4037.
DHCH1 is an essential gene with NADP(+)-dependent methylene tetrahydrofolate DH and 5,10-methenyltetrahydrofolate CH activities. [DHCH1] (Mus musculus) PubMed
4038.
Despite the fact that dihydroxyacetonephosphate acyltransferase is important for virulence the null mutant still exhibited the typical characteristics of metacyclics.[ dihydroxyacetonephosphate acyltransferase] (Mus musculus) PubMed
4039.
GT78 is a novel UDP-galactose:fucoside alpha3-galactosyltransferase that modifies Skp1 in the cytoplasm of Dictyostelium (Mus musculus) PubMed
4040.
Ile(104) substitutions perturb the equilibrium between inactive and active cAR1 conformations in favour of the latter. (cAR1) (Mus musculus) PubMed
4041.
study shows by single-molecule microscopy an agonist-induced increase in mobile fraction of cAMP-receptor at the leading edge of chemotacting Dictyostelium; onset of receptor mobility was correlated to uncoupling & activation of Galpha2-protein [cAR1] (Mus musculus) PubMed
4042.
Inactivation of dupA resulted in depressed L. pneumophila growth and sustained hyperphosphorylation of ERK1. [Erk1, DupA] (Mus musculus) PubMed
4043.
These results suggest that Dictyostelium utilises a distinct Xpf nuclease-mediated repair process to remove crosslinked DNA.[Xpf, Rev3] (Mus musculus) PubMed
4044.
SAP1 is essential for liver infection possibly by controlling the expression of infectivity-associated parasite effector genes. [Sap1] (Mus musculus) PubMed
4045.
we characterized two respiratory dehydrogenases, succinate:ubiquinone reductase (complex II) and alternative NADH dehydrogenase (NDH-II),in Plasmodium yoelii yoelii (Mus musculus) PubMed
Here we report the identification and characterization of TcrPDEA1, a singular phosphodiesterase of T. cruzi which is resistant to the typical phosphodiesterase inhibitors, such as IBMX, papaverine and theofylline.[TcrPDEA1] (Mus musculus) PubMed
4048.
The precise temporal expression of the T. cruzi-specific protein Met-III is reported.[Met-III] (Mus musculus) PubMed
4049.
In this study, the metacaspases, MCA3 and MCA5 were expressed and indirect evidence of their participation in programmed cell death was obtained, induced by fresh human serum. [Metacaspase 3, Metacaspase 5] (Mus musculus) PubMed
4050.
identified parvulin TcPIN1 (parvulin peptidyl-prolyl cis/trans isomerase)as a homolog of the human hPin1 PPI. [PIN1] (Mus musculus) PubMed
4051.
Recombinant T. cruzi Protein geranylgeranyltransferase type I (PGGT-I) showed activity with distinct specificity toward the C-terminal CaaX motif of protein substrates. [PGGT-I] (Mus musculus) PubMed
4052.
TcMCP-1 is a metallocarboxypeptidase with a catalytic metal ion in the active site. [TcMCP-1] (Mus musculus) PubMed
4053.
Trypanosoma have a conserved Mago and a divergent Y14 protein. [Y14] (Mus musculus) PubMed
4054.
The G5 domain of aap dimerizes in the presence of Zn(2+), incorporating 2-3 Zn(2+) ions in the dimer interface for biofilms[aap protein] (Mus musculus) PubMed
4055.
The activation and aminoacylation properties of D. hafniense Pyrrolysyl-tRNA synthetase and the nature of the pyrrolysine tRNA identity elements were determined (Pyrrolysyl-tRNA synthetase). (Mus musculus) PubMed
4056.
binding of a potent effector molecule to reduced CprK1 induces local changes in the N-terminal effector binding domain[CprK1] (Mus musculus) PubMed
4057.
The apo 2.1A resolution structure of the intact D. hafniense pyrrolysyl-tRNA synthetase (PylS)was reported. (PylS) (Mus musculus) PubMed
4058.
The transcriptional regulator CprK induces expression of halorespiratory genes and is reversibly inactivated by oxygen. [CprK] (Mus musculus) PubMed
4059.
Desulfitobacterium hafniense PylRS-tRNA(Pyl) is an orthogonal pair in vitro and in vivo, and present the crystal structure of this orthogonal pair [Pyrrolysyl-tRNA synthetase] (Mus musculus) PubMed
4060.
Cel5G, Cel5H, and Cel5J were identified as processive endoglucanases acting on the beta-1,4 bonds linking cellobiose units in cellulose degradation. [Cel5G, Cel5H, Cel5J] (Mus musculus) PubMed
4061.
on the basis of the data, Glutamate-134 is intrinsically involved in the hydrolysis reaction catalyzed by DapE and likely plays the role of a general acid and base [DapE] (Mus musculus) PubMed
4062.
sequence-activity relationships and key residues of porin P2 Loop 7 were identified; ability of mutant peptides to induce activation of signal transduction pathways and release of TNF-alpha and IL-6 has been determined [porin P2] (Mus musculus) PubMed
4063.
all TpsB proteins have a modular structure, with a periplasmic domain that interacts with the cognate TpsA protein and with pore forming activity contained within the C terminus[HMW1B] (Mus musculus) PubMed
4064.
Results present the crystal structure of the C-terminal end of Hia, corresponding to the entire Hia translocator domain and part of the passenger domain (residues 992-1098). (Mus musculus) PubMed
4065.
The structure of SiaP in the presence of the sialic acid analogue 2,3-didehydro-2-deoxy-N-acetylneuraminic acid reveals the ligand bound in a deep cavity with its carboxylate group forming a salt bridge with a highly conserved Arg residue [SiaP] (Mus musculus) PubMed
4066.
isolated and characterized biophysical properties of HI1462 in relation to TolC in E coli. [HI1462] (Mus musculus) PubMed
4067.
study concludes that the NTHi vapBC-1 gene pair functions as a classical Toxin-antitoxin locus and that the induction of VapC-1 RNase activity leads to growth inhibition via the mechanism of mRNA cleavage[VapB-1 and VapC-1] (Mus musculus) PubMed
4068.
Results demonstrate that mutation of the invariant glycine (G418A) within motif 2 led to attenuated transport activity, while mutation of the invariant glycine (G155A/V/E) within motif 1 had no discernible effect on activity [FbpA, FbpB, FbpC] (Mus musculus) PubMed
4069.
The recognition site for the Mod methyltransferase in H. influenzae is 5'-CGAAT-3' (mod). (Mus musculus) PubMed
4070.
In the current study, examination of purified HMW1B by size exclusion chromatography and negative staining electron microscopy revealed that the predominant species was a dimer.[HMW1B] (Mus musculus) PubMed
4071.
In this study, we identified SiaR as a repressor of sialic acid transport and catabolism in nontypeable Haemophilus influenzae.[SiaR] (Mus musculus) PubMed
4072.
An extensive secondary structure at the 5' end of sxy mRNA sequesters the ribosome-binding site and start codon in a stem-loop (sxy). (Mus musculus) PubMed
4073.
In a collection of NTHI strains we found several strains in which there were two distinct but variant lic1D DNA sequences, genes predicted to encode the transferase responsible for directing the addition of PCho to LPS.[Lic1D] (Mus musculus) PubMed
4074.
data strongly suggest that the mechanism of phosphotransfer in the uridyltransferase reaction in GlmU is primarily through an associative mechanism with a pentavalent phosphate intermediate and an inversion of stereochemistry [GlmU] (Mus musculus) PubMed
4075.
In conclusion, we have discovered a novel non-typable Haemophilus influenzae outer membrane protein, protein E, with adhesive properties.[protein E in strain 772] (Mus musculus) PubMed
4076.
results indicate that dsbA is required in vivo and that HbpA and additional DsbA-dependent factors are likely to participate in H. influenzae pathogenesis [dsbA] (Mus musculus) PubMed
4077.
Aspartate 139 in the active site of serine acetyltransferase, in dyad linkage with histidine154, likely facilitates catalysis by increasing the basicity of His154; aspartate139 may also play a role during the catalytic reaction. (serine acetyltransferase) (Mus musculus) PubMed
4078.
HMW1 is a glycoprotein with an unusual N-linked carbohydrate modification; its glycosylation requires a glycosyltransferase with a novel activity (Mus musculus) PubMed
4079.
catalytic and structural properties of the H67A and H349A dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) from Haemophilus influenzae were investigated [DapE] (Mus musculus) PubMed
4080.
mucosal immunization of mice with rP2 induces antibodies that recognize surface exposed epitopes on multiple strains, indicating that P2 is a candidate for development of a mucosal vaccine for nontypeable Haemophilus influenzae[OMP P2 ] (Mus musculus) PubMed
4081.
The results suggest that BtuCD as a prototype type II ABC importer may have a mechanism that is distinct from that of ABC exporters such as Sav1866 or type I ABC importers such as those specific for molybdate (ModBC) or maltose (MalFGK). (BtuCD) (Mus musculus) PubMed
4082.
data suggest that the ubiquitous adhesin protein E plays an important role in the pathogenesis of nontypeable Haemophilus influenzae infection [adhesin protein E] (Mus musculus) PubMed
4083.
Here we describe the structure of YfeU and discuss the possible function as an etherase possibly involved in peptidoglycan recycling. (Mus musculus) PubMed
4084.
Canadian beta-lactamase-negative Haemophilus influenzae isolates were found to have the N526K mutations in their ftsI genes, and their ampicillin MIC(50) values were 4-8 times that of beta-lactamase-negative ampicillin-susceptible strains [ftsI] (Mus musculus) PubMed
4085.
The first structure of a member of the immunoglobulin A protease family at 1.75-A resolution was reported. (IgAP1) (Mus musculus) PubMed
4086.
Haemophilus influenzae beta-carbonic anhydrase is an allosteric enzyme that can adopt active and inactive conformations, the latter of which is stabilized by bicarbonate ion binding to a non-catalytic site. (beta-carbonic anhydrase). (Mus musculus) PubMed
4087.
YbaB was demonstrated to be a DNA-binding protein (YbaB) (Mus musculus) PubMed
4088.
findings revealed that MADS1 played a role in specifying lemma and palea and acted as a repressor of overdevelopment of lemma and palea; it was indicated that MADS1 upregulated the transcript level of AP3 homologue MADS16 [MADS1, MADS16] (Mus musculus) PubMed
4089.
EUI1 plays a negative role in gibberellin-mediated regulation of cell elongation in the uppermost internode of rice [EUI1] (Mus musculus) PubMed
4090.
results suggest that gibberellin modulates the activity of mitochondrial pyruvate dehydrogenase by regulating PDK1 expression and subsequently controlling plant growth and development [OsPDK1] (Mus musculus) PubMed
4091.
results supply genetic evidence that a plant Glu receptor-like gene, rice GLR3.1, is essential for the maintenance of cell division and individual cell survival in the root apical meristem at the early seedling stage [GLR3.1] (Mus musculus) PubMed
4092.
The GOLD HULL AND INTERNODE2 (GH2) gene in rice encodes a cinnamyl-alcohol dehydrogenase (CAD) functioning to synthesize coniferyl and sinapyl alcohol precursors in rice lignin biosynthesis. (Mus musculus) PubMed
4093.
first time that the function of a rice UGT has been characterized [UGT5] (Mus musculus) PubMed
4094.
only one member of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHPS1) family expresses in close correlation with phenylalanine ammonialyase [DAHPS1] (Mus musculus) PubMed
4095.
These results suggest that OsPPT1a is a functional p-hydroxybenzoate polyprenyltransferase (PPT) involved in ubiquinone (UQ) biosynthesis in Oryza sativa [OsPPT1a]. (Mus musculus) PubMed
4096.
Three of the four major clades of GSKs present in Arabidopsis and rice were established early in the evolutionary history of extant seed plants. (Mus musculus) PubMed
4097.
The rice genome has 4 RAD21-like genes that share lower than 21% identity at polypeptide levels, and each is present as a single copy in this genome.[OsRAD21-24] (Mus musculus) PubMed
4098.
findings show that human selection of an amino acid substitution in the predicted DNA binding domain encoded by sh4, a gene of previously unknown function, was primarily responsible for the reduction of grain shattering in rice domestication [sh4] (Mus musculus) PubMed
4099.
characterization of the rice leafy-head2 (lhd2) mutant that exhibits shortened plastochron, dwarfism, reduced tiller number, and failure of phase transition from vegetative to reproductive growth[leafy head2] (Mus musculus) PubMed
4100.
The modified GLP-1 (mGLP-1) gene was enlarged to 5xmGLP-1 (mGLPx5) by tandem repeat. Endoplasmic reticulum (ER) is a suitable intracellular organelle for accumulation of mGLPx5 peptide [GLP-1]. (Mus musculus) PubMed
4101.
OsIAA3 is one of the IAA gene family members whose expression is rapidly increased in response to auxin; results suggest that, in rice, auxin is important for development and its signaling is mediated by IAA genes [IAA3] (Mus musculus) PubMed
4102.
This gene is probably a new excessive tillering gene in rice and is designated tentatively ext-M1B (t). (Mus musculus) PubMed
4103.
results show that, at both a transcriptional and a transductional level, OsFK1 is preferentially expressed under aerobic conditions, whereas OsFK2 is induced under anoxia [FK1 & FK2] (Mus musculus) PubMed
4104.
These revealed high expression levels of the reporter genes directed by the rsus3 promoter in guar endosperm.[sucrose synthase] (Mus musculus) PubMed
4105.
Nuclear ACR7 interacts with nucleocytoplasmic HSP18.0-CII in vivo. The potential ability of nuclear protein ACR7 to bind Gln and the possibility of the protein acting as a Gln sensor in rice leaves is discussed [ACR7]. (Mus musculus) PubMed
4106.
The full-length cDNA (3612 bp) of OsNHA1 was cloned by RT-PCR approach from rice (Oryza sativa L.), which encodes a putative plasma membrane Na+/H+ antiporter. (Mus musculus) PubMed
4107.
Four alternative transcripts of OsFCA were cloned from the leaves of rice, and designated as OsFCA-1, OsFCA-2, OsFCA-3 and OsFCA-4 respectively. OsFCA-1 was homologous to FCA-gamma of Arabidopsis (Mus musculus) PubMed
4108.
A novel blast-inducible RING-H2 type zinc finger protein gene OsRING-1 was cloned from rice by cDNA library screening. (Mus musculus) PubMed
4109.
Cloning, characterization and tissue-specific expression of a putative EMBRYONIC FLOWER 2 (EMF2) gene in Oryza sativa. (Mus musculus) PubMed
4110.
The isolation and characterization of BTH-Induced MAP Kinase 2 (BIMK2) is reported. [BIMK2] (Mus musculus) PubMed
4111.
Oscry1s are responsible for regulating blue light-mediated de-etiolation in rice. OsCRY2 is involved in the flowering time in rice [OsCRY1 and OsCRY2]. (Mus musculus) PubMed
4112.
Expression patterns for PPCK1, PPCK2, and PPCK3 genes in rice are discussed. [PPCK1][PPCK2][PPCK3] (Mus musculus) PubMed
4113.
A rice cDNA encoding a putative arginine decarboxylase (ADC) protein, a key enzyme involved with putrescine (Put) biosynthesis in plants was cloned and characterized.[ADC1] (Mus musculus) PubMed
4114.
Mutations in the Rymv1 gene are associated with resistance to Rice yellow mottle virus. [Rymv1] (Mus musculus) PubMed
4115.
Treatment of seedlings with a histone deacetylase (HDAC) inhibitor, trichostatin A, increased acetylation of histones H3 and association of RNA polymerase II on the ADH1 and PDC1 loci, thereby increasing transcript levels of ADH1 and PDC1 [ADH1 and PDC1]. (Mus musculus) PubMed
4116.
OsDOS is a novel nuclear protein that delays leaf senescence likely, at least in part, by integrating developmental cues to the JA pathway. (Mus musculus) PubMed
4117.
isolated a Lon protease gene, OsLon1, from Oryza sativa; the OsLon1 gene was successfully expressed in E. coli and the detected protein size, about 120 kDa, matched the expected molecular mass of the His-tagged OsLon1 protein (Mus musculus) PubMed
4118.
OsEIL1 is involved in ethylene signal transduction pathway and acts as a positive regulator of ethylene response in rice. (Mus musculus) PubMed
4119.
1:PEX5L, a splice variant of the type I peroxisomal targeting signal (PTS1) receptor, is cloned and characterized. [PEX5L] 2:PEX5S, a splice variant of the type I peroxisomal targeting signal (PTS1) receptor, is cloned and characterized. [PEX5S] (Mus musculus) PubMed
4120.
GAMYB, GAMYBL1, and GAMYBL2 are regulated by microRNA miR159 in flowers. [GAMYB, GAMYBL1, and GAMYBL2] (Mus musculus) PubMed
4121.
Xanthomonas oryzae pv. oryzae commandeers the regulation of otherwise developmentally regulated host genes to induce a state of disease susceptibility [Os8N3] (Mus musculus) PubMed
4122.
There are synergistic interactions between RISBZ1 and RPBF involved in the recognition of a GCN4 target motif TGA(G/C)TCA. [RPBF]& [RISBZ1] (Mus musculus) PubMed
4123.
RPP10 is encoded by a single gene and has high homology to acyl-CoA-binding proteins from other plants. (Mus musculus) PubMed
4124.
Salicylic Acid and NaCl are inducers for pib promoter. [pib] (Mus musculus) PubMed
4125.
Xa21 mediated the disease resistance against Xanthomonas oryzae pv. oryzae. [Xa21] (Mus musculus) PubMed
4126.
cloning of the cDNA of FY; results indicate that the autonomous flowering pathway is present in monocots, and the regulation through FY and FCA interaction is conserved between monocots and dicots [FY, FCA] (Mus musculus) PubMed
4127.
CEBiP plays a key role in the perception and transduction of chitin oligosaccharide elicitor in the rice cells[CEBiP] (Mus musculus) PubMed
4128.
Green rice leafhopper resistance 5 (Grh5) is located on the distal region of the long arm of chromosome 8 and tightly linked to the simple sequence repeat markers RM3754 and RM3761. (Mus musculus) PubMed
4129.
Identification of Ala(111), Gly(123) and Ser(127)as key amino-acids in OsCaM61 that play a vital role in suitable changes of rice calmodulin-binding kinase conformation for kinase activation (OsCaM61). (Mus musculus) PubMed
4130.
isolateion & identification of a full-length cDNA, OsBISAMT1 which encodes a putative S-adenosyl-L: -methionine:salicylic acid carboxyl methyltransferase; it may be involved in disease resistance responses as well as in wound response in rice [BISAMT1] (Mus musculus) PubMed
4131.
IRO2 is involved in the regulation of gene expression under Fe-deficient conditions. [IRO2] (Mus musculus) PubMed
4132.
Gamma-Aminobutyrate transaminase (GABA-T)expression is induced by blast fungus infection, mechanical wounding and ultraviolet radiation in rice leaves and is not detected in normal rice organs. (Mus musculus) PubMed
4133.
The isolation and physical mapping of tms5 (thermosensitive genic male sterile 5) in in 3 rice populations are reported.[tms5] (Mus musculus) PubMed
4134.
identification of a cluster of three genes at the Sub1 locus, encoding putative ethylene response factors [Sub1A] (Mus musculus) PubMed
4135.
The MYBGA-GA Response Element interaction affects sugar feedback control in balanced energy production during seedling growth. [MYBGA] (Mus musculus) PubMed
4136.
These data suggest that SNAC1 holds promising utility in improving drought and salinity tolerance in rice.[Snac1] (Mus musculus) PubMed
4137.
The expression pattern of OSBZ8 directly correlates with the ability of the rice cultivar to tolerate salt stress (OSBZ8). (Mus musculus) PubMed
4138.
Sugar specificities of class III (OsChib1a) and class I (OsChia1cDeltaChBD) from Oryza sativa L.were investigated by nuclear magnetic resonance spectra of the enzymatic products from partially N-acetylated chitosans.(OsChib1a)(OsChia1cDeltaChBD) (Mus musculus) PubMed
4139.
RIP1 is probably a nuclear protein that may form a functional complex with other proteins and carry out essential cellular and developmental roles during the late stage of pollen formation. (Mus musculus) PubMed
4140.
The isolation and characterization of three floral organ number4 (fon4) alleles and the cloning of the FON4 gene in O. sativa is reported.[fon4] (Mus musculus) PubMed
4141.
The comparatively broader substrate range of this EGase with respect to beta-1,4-glycan backbones (glucose and xylose) may partly reflect different roles of gramineous and non-gramineous GHF9 enzymes.[EGase] (Mus musculus) PubMed
4142.
OsCel9A reveals a broad substrate specificity with respect to sugar backbones (glucose and xylose) in beta-1,4-glycans of type II cell wall. (Mus musculus) PubMed
4143.
FON2 transcripts are localized at the apical region in all meristems in the aerial parts of rice plants, showing an expression pattern similar to that of Arabidopsis CLV3 [FON2]. (Mus musculus) PubMed
4144.
data suggest that OsAGAP has a specific role in regulating vesicle trafficking pathways such as the auxin influx pathway, which in turn controls auxin-dependent root growth in plants [AGAP] (Mus musculus) PubMed
4145.
results indicate that a single amino acid in the xxLxLxx motif may be critical for maintaining the recognition surface of Pi2 and Piz-t to their respective avirulence proteins [Pi2 and Piz-t] (Mus musculus) PubMed
4146.
Results showed that the expression level of rice UDT1 and GAMYB were reduced in msp1-4, implying that UDT1 and GAMYB are possibly the downstream genes of MSP1 gene in rice pollen development: [UDT1, GAMYB] (Mus musculus) PubMed
4147.
Study describes the cloning and identification of a rice cDNA, OsTVLP1, encoding a protein with similarity to TGF-beta receptor interacting proteins and vacuolar assembly Vam6p/Vps39p proteins. [TVLP1 protein] (Mus musculus) PubMed
4148.
1) Expression of PBZ1 is regulated by gibberellic acid signalling and stress stimuli. [PBZ1] 2)GID1 is involved in tolerance to cold stress and resistance to blast fungus. [GID1] (Mus musculus) PubMed
4149.
cloning of OsAtg4 and OsAtg8 from Oryza sativa; detected their expression patterns in various tissues[OsAtg4]& [OsAtg8] (Mus musculus) PubMed
4150.
OsHKT1, OsHKT2, and OsVHA confer salt tolerance by maintaining a low cytosolic Na(+) level and a correct ratio of cytosolic Na(+)/K(+). [OsHKT1, OsHKT2, and OsVHA] (Mus musculus) PubMed
4151.
Complementation analyses for HTD1 confirm that the defect in HTD1 is responsible for both high-tillering and dwarf phenotypes in the htd1 mutant; HTD1 is an ortholog of MAX3 in A. thaliana.[HTD1] (Mus musculus) PubMed
4152.
OsSUT1 is present in the companion cells and sieve elements of the scutellar vascular bundle, where it may have a role in phloem loading of sucrose for transport to the developing shoot and roots. (Mus musculus) PubMed
4153.
These results indicate that TDR is a key component of the molecular network regulating rice tapetum development and degeneration.[TDR] (Mus musculus) PubMed
4154.
The characterization of a T-DNA insertional mutant in the Wax-deficient anther1 (Wda1) gene of rice (Oryza sativa), which shows significant defects in the biosynthesis of very-long-chain fatty acids in both layers, is reported.[Wda1] (Mus musculus) PubMed
4155.
The isolation and characterization of salt overly sensitive 1 (SOS1) in O. sativa is reported. (Mus musculus) PubMed
4156.
These results indicate that Xb3 is necessary for full accumulation of the XA21 protein and for Xa21-mediated resistance.[XB3] (Mus musculus) PubMed
4157.
The albino trait was controlled by a single recessive gene that's tantatively referred to as al12. [al12] (Mus musculus) PubMed
4158.
Fluorescence investigations of phytochrome (phy) in rice (Oryza sativa L. cv. Nipponbare) mutants deficient in phyA, phyB and phyA plus phyB were performed [phyA] (Mus musculus) PubMed
4159.
Secretory carrier membrane protein 1 (SCAMP1) localizes to the early endosome. [SCAMP1] (Mus musculus) PubMed
4160.
Study shows that the seed shattering is controlled by a single dominant gene, Shattering1 (SHA1), encoding a member of the trihelix family of plant-specific transcription factors. [SHA1 protein] (Mus musculus) PubMed
4161.
YABBY1 is involved in regulating the differentiation of a few specific cell types and is unrelated to polar regulation of lateral organ development [YABBY1] (Mus musculus) PubMed
4162.
The isolation and characterization of Lti6b in rice is reported.[Lti6b] (Mus musculus) PubMed
4163.
results demonstrated that the Rcn1 gene was not involved in the D3-associated pathway in tillering control [RcnI, D3] (Mus musculus) PubMed
4164.
NADP-ME2 has a role in enhancing tolerance of plants to salt and osmotic stress. [NADP-ME2] (Mus musculus) PubMed
4165.
SET Domain Group Protein 714 (SDG714) is involved in DNA methylation, the transposition of transposable elements, and genome stability in rice. [SDG714] (Mus musculus) PubMed
4166.
Expression of Lsi1 is required for the transport of Si through the cells of the exodermis and endodermis, is regulated by abscisic acid and displays a diurnal pattern. (Mus musculus) PubMed
4167.
OsCSLD1 function is required for hair elongation but not initiation. [CSLD1] (Mus musculus) PubMed
4168.
The LONELY GUY (LOG) gene of rice is required to maintain meristem activity and its loss of function causes premature termination of the shoot meristem [LOG] (Mus musculus) PubMed
4169.
Rice myosin gene controlled pollen development by sensing changed environmental factors.(Myosin XIB) (Mus musculus) PubMed
4170.
The role of SSIIIa during starch synthesis in rice endosperm is reported.[SSIIIa] (Mus musculus) PubMed
4171.
The results suggest that CDPK13, calreticulin and CRTintP1 might be important signaling components for response to cold stress in rice.[CDPK13, CRTintP1 proteins] (Mus musculus) PubMed
4172.
Upregulation of MUS81 in response to DNA radiation damage is reported.[MUS81] (Mus musculus) PubMed
4173.
The OsLPLA gene, which encoded 270 amino acids, was located on an approximately 21 Mb of chromosome 8 on the physical map of Oryza sativa Japonica type. OsLPLA transcripts were abundantly expressed in leaves and developing seeds.[LPLA] (Mus musculus) PubMed
4174.
The results suggest that OsSNAP32 belongs to a novel member of this gene family encoding SNAP25-type proteins, involved in the rice responses to biotic and abiotic stresses.[OsSNAp32] (Mus musculus) PubMed
4175.
purification and characterization of ACR2.1 and ACR2.2; ACR2.1 and, to a lesser extent, ACR2.2 exhibit bifunctional activities as phosphatases and arsenate reductases [ACR2.1, ACR2.2] (Mus musculus) PubMed
4176.
These results demonstrate that rice Ugp1 is required for callose deposition during pollen mother cells meiosis and bridges the apoplastic unloading pathway and pollen development.[Ugp1] (Mus musculus) PubMed
4177.
A phosphate starvation-induced acid phosphatase cDNA was cloned from the rice, Oryza sativa. The cDNA encoding O. sativa acid phosphatase (OsACP1) has 1100 bp with an open reading frame of 274 amino acid residues. (Mus musculus) PubMed
4178.
NYC1 plays essential roles in the regulation of light-harvesting complex II and thylakoid membrane degradation during rice senescence.[ (Mus musculus) PubMed
4179.
enhancing the Fe3+ chelate-reductase activity of rice plants that normally have low endogenous levels confers resistance to Fe deficiency[ferric citrate iron reductase] (Mus musculus) PubMed
4180.
data together suggest that SRT1 is required for safeguard against genome instability and cell damage to ensure plant cell growth [SRT1] (Mus musculus) PubMed
4181.
LA1 plays a negative role in polar auxin transport (PAT). Loss-of-function of LA1 enhances PAT greatly & alters endogenous IAA distribution in shoots, leading to reduced gravitropism, & therefore tiller-spreading phenotype of rice plants[LA1] (Mus musculus) PubMed
4182.
In senescing leaves, Sgr regulates chlorophyll (Chl) degradation by inducing light-harvesting chlorophyll binding protein(LHCPII) disassembly through direct interaction.[Sgr] (Mus musculus) PubMed
4183.
The results suggest that OsBISERK1 may be involved in disease resistance responses in rice.[OsBISERK1] (Mus musculus) PubMed
4184.
We present a detailed characterization of the chitin oligosaccharide elicitor-induced transcriptional activator gene. It plays important roles in elicitor-induced defense signaling pathways in rice.[OsWRKY53] (Mus musculus) PubMed
4185.
ygl1 locus was mapped to chromosome 5 and isolated by map-based cloning; sequence analysis revealed that it encodes the chlorophyll synthase [Ygl1] (Mus musculus) PubMed
4186.
The OsGluRS gene (TIGR locus Os02 g02860) which encode glutamyl-tRNA synthetase was identified as the Cde1(t) gene.[Cde1(t)] (Mus musculus) PubMed
4187.
RZF71 may play an important role in rice responses to salt and osmotic stresses as a transcription factor.[RZF71] (Mus musculus) PubMed
4188.
over-expression of COIN enhanced tolerance to cold, salt and drought and increased cellular proline level [COIN] (Mus musculus) PubMed
OsDMC1 is essential for rice meiosis and plays an important role in homologous pairing[OsDMC1 ] (Mus musculus) PubMed
4191.
The C-terminal extension of OsGAD2 plays a role as a strong autoinhibitory domain, and truncation of this domain causes the enzyme to act constitutively, with higher activity both in vitro and in vivo. (Mus musculus) PubMed
4192.
UGE-1 over-expressed in A. thaliana conferred tolerance to salt, drought and freezing stress, and increased raffinose metabolism without altering plant morphology.[UGE-1] (Mus musculus) PubMed
4193.
Identification of Pi39(t), gene conferring the broad-spectrum resistance to Magnaporthe oryzae.[Pi399(t)] (Mus musculus) PubMed
4194.
These results suggest that RTBP1 plays dual roles in rice (Oryza sativa), as both a negative regulator of telomere length and one of positive and functional components for proper architecture of telomeres.[RTBP-1] (Mus musculus) PubMed
4195.
In 3 elite rice varieties, the resistance conferring allele of the rice blast resistance gene Pi33 was introgressed from the wild rice Oryza rufipogon. (Mus musculus) PubMed
4196.
results showed that constitutive expression of FCA RNA recognition motifs (RRMs) could regulate cellular size [FCA] (Mus musculus) PubMed
4197.
A role for WRKY45 in Benzothiadiazole-induced and salicylic acid-mediated defense signaling in rice, is proposed. [WRKY45] (Mus musculus) PubMed
4198.
results indicate that the product of DSH1 may be involved in plant viability or reproductive processes, and that the phenotype of sterility is apparently caused by loss of function of DSH1 in the stigma [DSH1] (Mus musculus) PubMed
4199.
Study describes the low silicon rice 2 (Lsi2) gene, which is constitutively expressed in the roots; the protein is localized, on the plasma membrane of cells in both the exodermis and the endodermis and is a silicon efflux transporter.[Lsi2 protein] (Mus musculus) PubMed
4200.
Cconstitutive expression of OsZIP4 changes the Zn distribution within rice plants and is a critical Zn transporter. (Mus musculus) PubMed
4201.
The gibberellin-dependent GID1-SLR1 interaction also occurs in planta.[GID1, SLR1] (Mus musculus) PubMed
4202.
D10 transcription has a role in the regulation of the branching inhibitor pathway. (Mus musculus) PubMed
4203.
APO1 positively regulates class-C floral homeotic genes, but not class-B genes. (Mus musculus) PubMed
4204.
The expressed OsGSTF5 is a phi class glutathione S-transferase and appears to play a role in the conjugation of herbicide.[OsGSTF5] (Mus musculus) PubMed
4205.
HSF13 was a class C heat shock factor with all the conserved sequence elements of heat stress transcription factor. [HSF13] (Mus musculus) PubMed
4206.
These results indicate that the germ cell-specific rice MEL1 gene regulates the cell division of premeiotic germ cells, the proper modification of meiotic chromosomes, and the faithful progression of meiosis.[MEL1] (Mus musculus) PubMed
4207.
These results demonstrate that Os BOR1 is required both for efficient boron uptake and for xylem loading of boron. [BOR1] (Mus musculus) PubMed
4208.
demonstrate a conserved function of OsBZR1 and an important role of 14-3-3 proteins in brassinosteroid signal transduction in rice[BZR1] (Mus musculus) PubMed
4209.
Molecular cloning and functional analysis of Stay Green Rice (SGR) in O. sativa is reported.[SGR] (Mus musculus) PubMed
4210.
findings show that a novel gene, VIRESCENT 2 (V2), encodes a new type of guanylate kinase GK (designated pt/mtGK) that is localized in plastids and mitochondria [viescent2] (Mus musculus) PubMed
4211.
the residues forming the hydrophobic cavity play various important roles in the structure and function of rice nsLTP2, nonspecific lipid transfer protein 2 . (Mus musculus) PubMed
4212.
This study analysed the rice pdc gene family and alterations in the efficacy of the ethanolic fermentation process, by production of transgenic plants over- and under-expressing Ospdc1 as well as over-expressing alcohol dehydrogenase proteins.[Ospdc1] (Mus musculus) PubMed
4213.
We identified a cleistogamous mutant harbouring a missense mutation (I45T) in the class-B MADS-box gene SUPERWOMAN1 (SPW1), which specifies the identities of lodicules (equivalent to petals) and stamens. [Spw1] (Mus musculus) PubMed
4214.
These studies demonstrated that SnRK1A is an important intermediate in the sugar signaling cascade.[SmRK1A] (Mus musculus) PubMed
4215.
The responses to temperature of transgenic rice plants with 130 and 35% of the wild-type (WT) Rubisco content by transformation with rbcS cDNA in sense and antisense orientations, respectively.[rbcS] (Mus musculus) PubMed
4216.
This article is the first report on the functional characterization of HMA9, a P(1B)-type metal efflux transporter, in O. sativa.[HMA9] (Mus musculus) PubMed
Repression of the rice RAR1 gene suppressed defense responses induced in the pti1a mutant, indicating that Pti1a negatively regulates RAR1-dependent defense responses.[Pti1a, RAR1] (Mus musculus) PubMed
4219.
A gene encoding a Myb-like domain transcription factor with homology to Arabidopsis KANADI is the most probable candidate for RL10(t) (RL10(t). (Mus musculus) PubMed
4220.
These results reveal a critical role of Os DCL4-mediated trans-acting-siRNA biogenesis in rice development.[DCL4] (Mus musculus) PubMed
4221.
Overexpression of OsLFL1 might delay the flowering of W378 by repressing the expression of Ehd1.[OsLFL1] (Mus musculus) PubMed
4222.
14-3-3 protein may play an important role in regulating ACS activity.(ASC) (Mus musculus) PubMed
4223.
OPR7 encodes the enzyme catalysing the reduction of natural (+)-cis-12-oxophytodienoate for jasmonic acid biosynthesis [OPR7] (Mus musculus) PubMed
4224.
cloning of ROMT-15 and ROMT-17; ROMT-15 and -17 are cation-dependent and mutation of the predicted metal binding sites resulted in the loss of the enzyme activity. [ROMT-17] (Mus musculus) PubMed
4225.
not only required for arbuscular mycorrhizal symbiosis in rice but also is able to complement a Medicago truncatula dmi3 mutant [Dmi3] (Mus musculus) PubMed
4226.
This study identified cis-acting elements and their binding proteins of rice WRKY13, a gene that plays a pivotal role in disease resistance against bacterial and fungal pathogens.[WRKY13] (Mus musculus) PubMed
4227.
OsPI8-1 has multiple endogenous roles on developmental regulation.[OsPI8-1] (Mus musculus) PubMed
4228.
IDEF1 overexpression leads to enhanced expression of the iron deficiency-induced transcription factor gene OsIRO2, suggesting the presence of a sequential gene regulatory network [IDEF1] (Mus musculus) PubMed
4229.
Numerous truncated transcripts of OsVP1 resulting from an unusual post-transcriptional processing, were detected in four rice cultivars; various proportions of the transcripts were associated with preharvest sprouting. (Mus musculus) PubMed
4230.
These results also suggest that OsWRKY31 might be a common component in the signal transduction pathways of the auxin response and the defense response in rice.[OsWRKY31] (Mus musculus) PubMed
4231.
study revealed that the JIOsPR10 protein was expressed in developmental tissues, including in flower and root; the protein was also expressed under abiotic stresses, such as occurs during senescence and wounding[JIOsPR10] (Mus musculus) PubMed
4232.
CutA1 proteins from Thermus thermophilus (TtCutA1) and Oryza sativa (OsCutA1) and Pyrococcus horikoshii (PhCutA1)were examined, in order to elucidate the stabilization mechanism of PhCutA1.[CutA1] (Mus musculus) PubMed
4233.
Results suggest that cytosolic Ca2+ concentration may modulate NADPH oxidase activity by regulating the interaction between Rac GTPase and Rboh: [NADPH oxidase] (Mus musculus) PubMed
4234.
Results indicate that Rac1, RAR1, HSP90, and HSP70 form one or more protein complexes in rice cells and suggest that these proteins play important roles in innate immunity in rice: [RAR1] (Mus musculus) PubMed
4235.
dh1 presented severer mutation phenotype under relatively longer daylight than under shorter daylight implied that shorter daylight induced the expression of gene(s) redundant to DH1 in function and partially compensated for the loss-of-function[DH1] (Mus musculus) PubMed
4236.
The functional roles of two close homologs, MADS22 and MADS55, in the control of meristem identity and flowering time are reported.[MADS22; MADS55] (Mus musculus) PubMed
4237.
UDP-glucose pyrophosphorylase 1 (UGPase1) plays a key role in pollen development as well as seed carbohydrate metabolism.[UGPase1] (Mus musculus) PubMed
4238.
rice OSBZ8 is the prime factor interacting with both typical ABRE(s) and ABRE-like sequences (OSBZ8). (Mus musculus) PubMed
4239.
Rice GH3-8, an auxin-responsive gene functioning in auxin-dependent development, activates disease resistance in a salicylic acid signaling- and jasmonic acid signaling-independent pathway.[GH3-8, expansin] (Mus musculus) PubMed
4240.
Transgenic rice plants were tolerant to salt and drought during anthesis stage without any yield penalty as compared to unstressed transgenic plants[OsiSAP8] (Mus musculus) PubMed
4241.
These results indicate that Hd3a and RFT1 act as floral activators under short-day conditions, and that RFT1 expression is partly regulated by chromatin modification.[Hd3a, RFT1] (Mus musculus) PubMed
4242.
OsEXO1 interacted with rice DNA polymerase lambda (OsPol lambda), the 70 kDa subunit b of rice replication protein A (OsRPA70b), and the 32 kDa subunit 1 of rice replication protein A (OsRPA32-1). [EXO1; RPA70b; RPA32-1; Pol lamba] (Mus musculus) PubMed
4243.
Results suggest that OsABI5 could regulate the adaptive stress response and plant fertility [OsABI5] (Mus musculus) PubMed
4244.
XRCC1 contributes to DNA repair pathways that differ from the mammalian Bbase escision repair system. [XRCC1] (Mus musculus) PubMed
4245.
Data show that rice contains two TPD1-like genes, OsTDL1A and OsTDL1B. Both are co-expressed with MSP1 in anthers during meiosis: [OsTDL1A, OsTDL1B and MSP1] (Mus musculus) PubMed
4246.
Results collectively suggest that OsRar1 and OsSGT1 might be differentially required for rice basal disease resistance (OsRar1 and OsSGT1). (Mus musculus) PubMed
4247.
The role of JASMONATE RESISTANT 1 (JAR1) in phytochrome metabolism and jasmonic acid signaling is reported.[JAR1] (Mus musculus) PubMed
4248.
Alternative splicing takes place in both OsMET1 genes and appears to be regulated in a tissue-specific manner.[OsMET1a, OsMET1b] (Mus musculus) PubMed
4249.
Subcellular localization of OsACR9 and its accumulation and cellular distribution in various rice organs were examined by transient expression analysis and immunological methods using a monospecific antibody, respectively.[Acr9] (Mus musculus) PubMed
4250.
OsNuc37, a glycoprotein localized in the nucleus, is the executor for DNA laddering.[OsNuc37] (Mus musculus) PubMed
4251.
IDEF2 bound to OsYSL2 promoter region containing the binding core site, suggesting direct regulation of OsYSL2 expression[ iron deficiency-responsive element 2 ] (Mus musculus) PubMed
4252.
This result indicates that DCW11 could play a role as a mitochondrial signal transduction mediator in pollen germination.[DCW11] (Mus musculus) PubMed
4253.
The 5' UTR intron of the rubi3 gene elevated gene expression of the GUS reporter gene mainly at mRNA accumulation level, but also stimulated enhancement at translational level (rubi3). (Mus musculus) PubMed
4254.
Overexpression of ZFP252 in rice increased the amount of free proline and soluble sugars, elevated the expression of stress defense genes and enhanced rice tolerance to salt and drought stresses (ZFP252). (Mus musculus) PubMed
4255.
Biosynthesis genes for jasmonate, ethylene, and reactive oxygen species, as well as putative downstream targets involved in the stress-related process, were up-regulated in OsMADS26-overexpressing plants. [MADS26] (Mus musculus) PubMed
4256.
The male sterility is controlled by a single recessive gene of add(t) which is mapped between the markers of R02004 (InDel) and RM300 (SSR) on chromosome 2.[add(t)] (Mus musculus) PubMed
4257.
VR1 is a new male fertility controlling gene located on chromosome 4 in rice (VR1). (Mus musculus) PubMed
4258.
OsMADS2 and OsMADS4 show unequal redundancy of class B function.[OsMADS2, OsMADS4] (Mus musculus) PubMed
4259.
OsTudor-SN is a component of the RNA transport particle, and may control storage protein biosynthesis by regulating one or more processes leading to the transport, localization and anchoring of their RNAs to the cortical ER. (Mus musculus) PubMed
4260.
The functional expression and characterization of Flavanone 3beta-hydroxylases from rice is reported.[F3H] (Mus musculus) PubMed
Data suggest that eIF-1 has a central function in salt-stress adaptation in rice by regulating ion accumulation and the intracellular redox status.[Os07g34589] (Mus musculus) PubMed
4263.
The function of granule-bound starch synthase I (GBSSI) in rice, including the synthesis of extra-long unit chains of amylopectin, is reported.[GBSSI] (Mus musculus) PubMed
4264.
The ORF79 protein is expressed from a dicistronic gene atp6-orf79 in rice [ORF79] (Mus musculus) PubMed
4265.
The function of the sucrose nonfermenting 1-related protein kinase2 (SnRK2) SAPK4 in the salt stress response of rice, is characterized.[SAPK4] (Mus musculus) PubMed
4266.
The docking model can well interpret the specificity of protein Pir7b towards the anilid moiety of the substrates and provide valuable structure information about the ligand binding to protein Pir7b.[Pir7b] (Mus musculus) PubMed
4267.
OsDREB1F gene encodes a transcription activator, and can specifically bind to DRE/CRT element(G/ACCGAC) but not to ABRE element (OsDREB1F). (Mus musculus) PubMed
4268.
OsTRBF1, OsTRBF2 and OsTRBF3 play combinatory roles in the function and structure of telomeres in rice. (OsTRBF1)(OsTRBF2)(OsTRBF3) (Mus musculus) PubMed
4269.
These results reinforced the possibility that OsXIP is involved in plant defense mechanisms against phytopathogens.[OsXIP] (Mus musculus) PubMed
4270.
Results indicate that Lsi6 is a transporter responsible for the transport of Si out of the xylem and subsequently affects the distribution of Si in the leaf: [Lsi6] (Mus musculus) PubMed
4271.
Three ATG triplets in the polylinker decreased the synthesis of the HKT1 transporter and that the lower amount of transporter caused the functional change.[HKT1] (Mus musculus) PubMed
4272.
Nodulin26-like Intrinsic Proteins (NIPs) OsNIP2;1 and OsNIP3;2 from Oryza sativa, and LjNIP5;1 and LjNIP6;1 from Lotus japonicus are bi-directional As(III) channels [Nodulin26-like Intrinsic Proteins (NIPs) OsNIP2;1 and OsNIP3;2] (Mus musculus) PubMed
4273.
Rice ceramidase uses ceramide instead of phytoceramide as a substrate, and is localized to the endoplasmic reticulum and Golgi. [Os01g43520] (Mus musculus) PubMed
4274.
Nal1 affects polar auxin transport as well as the vascular patterns of rice plants and plays an important role in the control of lateral leaf growth. (Mus musculus) PubMed
4275.
The results suggest that OsDRF1 plays a role in disease resistance via upregulating defense-related gene expression. [OsDRF1] (Mus musculus) PubMed
4276.
Wax Crystal-Sparse Leaf1 encodes a beta-ketoacyl CoA synthase involved in biosynthesis of cuticular waxes on rice leaf[WSL1] (Mus musculus) PubMed
4277.
The strand-exchange activity of the Oryza sativa DMC1A protein was much higher than that of the DMC1B protein (DMC1A and DMC1B). (Mus musculus) PubMed
4278.
Data show that Spl11 mutants have delayed flowering under long-day conditions and that SPL11 negatively regulates Spin1 transcript levelspossibly via ubiquitination: [SPIN1] (Mus musculus) PubMed
4279.
The identification and characterization of a DROOPING LEAF (DL) mutation in the descendants of a mutable line, IM294, are reported. (Mus musculus) PubMed
4280.
The expression pattern of SHOOT ORGANIZATION2 in developing rice leaves is reported.[SHO2] (Mus musculus) PubMed
4281.
Study reports the cloning of a newly identified QTL, qSW5 (QTL for seed width on chromosome 5), involved in the determination of grain width in rice.[qSW5] (Mus musculus) PubMed
4282.
These results suggest that there may be a conserved function between OsFVE and FVE in the control of flowering time.[OsFVE] (Mus musculus) PubMed
4283.
Results strongly suggest that Pho1 plays a crucial role in starch biosynthesis in rice endosperm at low temperatures and that one or more other factors can complement the function of Pho1 at high temperatures: [Pho1] (Mus musculus) PubMed
4284.
The expression pattern of the rubi3 promoter as well as the effects of the rubi3 5'-UTR (5' untranslated region) intron and the 5' terminal 27 bp of the rubi3 coding sequence on the activity of the promoter in transgenic rice plants, was analyzed.[Rubi3] (Mus musculus) PubMed
4285.
Thehe rice CYP85A1 (OsCYP85A1) enzyme functions as a CS synthase rather than both CS synthase and BL synthase were examined. (OsCYP85A1) (Mus musculus) PubMed
4286.
Transcripts of sucrose transporter OsSUT2M were higher in source leaf blades than in other organs at the same development stage, whereas transcripts of sucrose transporter OsSUT5Z were less traceable in all organs investigated [OsSUT2M and OsSUT5Z] (Mus musculus) PubMed
4287.
These results suggest that the diacylglycerol kinase OsBIDK1 may play a role in disease resistance responses [BIDK1]. (Mus musculus) PubMed
4288.
These results suggest that the OsMADS1 intragenic sequence, largely intron 1, contains a key regulatory region(s) essential for expression.[OsMADS1] (Mus musculus) PubMed
4289.
This is the first report on in vitro characterization of Rad51 protein from crop plants.[OsRAD51] (Mus musculus) PubMed
4290.
Degradation of ROOT ARCHITECTURE ASSOCIATED1 is essential for the onset of anaphase in the cell cycle during root development. [OsRAA1] (Mus musculus) PubMed
4291.
Complementary DNA clones of both BAD1 and BAD2 were isolated and expressed in E. coli. [BAD1, BAD2] (Mus musculus) PubMed
4292.
These data indicate that the three cell-wall invertase genes play complementary/synergetic roles in assimilate unloading during the grain filling stage.[OsCIN1, OsCIN2, OsCIN3] (Mus musculus) PubMed
4293.
To study the effects of growing rice leaves under the treatment of elevated CO(2), changes in photosynthesis, photosynthate accumulation, sucrose phosphate synthase and sucrose synthase and their gene expressions were measured.[SPS, SS]] (Mus musculus) PubMed
4294.
PDF1B mutants have severe defects in chloroplasts and mild defects in mitochondria. Gene expression in both organelles was altered. [PDF1B] (Mus musculus) PubMed
4295.
Results suggest that RACK1A functions in rice innate immunity by interacting with multiple proteins in the Rac1 immune complex: [RACK1A] (Mus musculus) PubMed
4296.
Thioredoxin m plays an important role in the redox regulation of chloroplast target proteins. Mutation of this gene inhibits growth and chloroplast development. [Ostrxm] (Mus musculus) PubMed
4297.
Rice Indeterminate 1 (RID1) gene acts as the master switch for the transition from the vegetative to reproductive phase.[RID1] (Mus musculus) PubMed
4298.
Os03g52760 is a myo-inositol kinase. Mutation leads to reductions in seed phytic acid. [OsMIK] (Mus musculus) PubMed
4299.
Crossing alloplasmic cytoplasmic male sterility lines of rices with wild-type rice harboring the mitochondrial orfH79 gene restores fertility. [orfH79] (Mus musculus) PubMed
4300.
rice JMJ706 encodes a heterochromatin-associated H3K9 demethylase involved in the regulation of flower development in rice[JMJ706] (Mus musculus) PubMed
4301.
NOL and NYC1 are co-localized in the thylakoid membrane and act in the form of a complex as a chlorophyll b reductase. [NOL; NYC1] (Mus musculus) PubMed
4302.
The recessive gene xa24 confers disease resistance to Xanthomonas oryzae at the seedling and adult stages. [xa24] (Mus musculus) PubMed
4303.
Co-expression patterns of sense and antisense OsDof12 transcipts might be attributed to the basically common nature of the two promoters (OsDof12). (Mus musculus) PubMed
4304.
OsCIPK23 is a multistress induced gene and likely mediates a signaling pathway commonly shared by both pollination and drought stress responses in rice.[CIPK23] (Mus musculus) PubMed
4305.
Pit is a rice blast resistance gene that is activated by insertion of a retrotransposon in the Pit promoter region. [Pit] (Mus musculus) PubMed
4306.
rpms1 and rpms2 interact in controlling male sterility. [rpms1; rpms2] (Mus musculus) PubMed
4307.
OscFBP1 is a cytosolic fructose-1,6-bisphosphatase plays a major role in the cytosolic conversion of triose-phosphates to sucrose and regulation of carbohydrate partitioning. [OscFBP1] (Mus musculus) PubMed
4308.
These results demonstrate that Xb15 encodes a protein phosphatase 2C that negatively regulates the XA21-mediated innate immune response [XB15]. (Mus musculus) PubMed
4309.
The altered expression levels of OsBADH2 gene influence aroma accumulation, and the prevalent aromatic allele probably has a single evolutionary origin.[OsBADH2] (Mus musculus) PubMed
4310.
Rice OsCASTOR can fully complement symbiosis defects in the corresponding Lotus mutant lines for both mycorrhizal and rhizobial symbiosis. [OsCASTOR] (Mus musculus) PubMed
4311.
Abscisic acid does not inhibit the interaction between the rice genes FCA and FY. [OsFca; OsFY] (Mus musculus) PubMed
4312.
OsbZIP23 has a major role in ABA-dependent drought and salinity tolerance and has high potential usefulness in genetic improvement of stress tolerance. (Mus musculus) PubMed
4313.
BC10 is a DUF266-containing Golgi-localized glycosyltransferase that is required for cell wall biosynthesis. [BC10] (Mus musculus) PubMed
4314.
Pikm-specific resistance is conferred by cooperation of Pikm1-TS and Pikm2-TS. (Mus musculus) PubMed
4315.
OsHsp90 functioned as a chaperone, binding to a subset of substrates, and maintained E. coli growth well at high temperatures. [Hsp90] (Mus musculus) PubMed
4316.
RETARDED PALEA1 is only expressed in palea primordium during early flower development. Ectopic expression of REP1 caused the asymmetrical overdifferentiation of the palea cells, altering their floral asymmetry. [REP1] (Mus musculus) PubMed
4317.
Os-CASTOR and Os-POLLUX are indispensable for mycorrhizal symbiosis in rice. Os-POLLUX can restore nodulation, but not rhizobial infection, to a Medicago truncatula dmi1 mutant. [CASTOR; POLLUX] (Mus musculus) PubMed
4318.
OsPht1;2 and OsPht1;6 are abundantly expressed under Pi starvation in rice. OsPT6 plays a broad role in Pi uptake, whereas OsPT2 is a low-affinity Pi transporter. [OsPht1;2 and OsPht1;6] (Mus musculus) PubMed
4319.
RIM1 functions as a host factor that is required for multiplication of Rice dwarf virus in rice. [RIM1] (Mus musculus) PubMed
4320.
EXTRA GLUME1 regulates rice empty-glume fate and spikelet development. EG1 is expressed strongly in inflorescence primordia and weakly in developing floral primordia. [EG1] (Mus musculus) PubMed
4321.
OsGSR1 is a positive regulator of the gbberellin response, and regulates brassinosteroid biosynthesis. [OsGSR1] (Mus musculus) PubMed
4322.
OsFLS2 is the rice ortholog of AtFLS2. It recognizes the flg22 peptide of flagellin. Overexpression enhances immune responses involving cell death but does not affect resistance to Acidovorax. [OsFLS2] (Mus musculus) PubMed
4323.
OsPIP2;7 is involved in rapid water transport and maintenance of the water balance in cells, and improves the tolerance of rice to low temperature stress. [OsPIP2;7] (Mus musculus) PubMed
4324.
starch branching enzyme I was characterized with respect to biochemical and crystallographic properties. [BEI] (Mus musculus) PubMed
4325.
OsSPX1 is induced specifically by phosphorus starvation in roots. [OsSPX1] (Mus musculus) PubMed
4326.
OsCDT1 functions to prevent entry of cadmium into yeast and plant cells and thereby enhance their Cd tolerance. [OsCDT1] (Mus musculus) PubMed
4327.
crystal structure of Oryza sativa GID1 (OsGID1) bound with GA(4) and GA(3) at 1.9 A resolution [GID1] (Mus musculus) PubMed
4328.
OsA8 not only influences the uptake of Phosphorus (P) by roots, but also the translocation of P from the roots to the shoots in rice.[OsA8] (Mus musculus) PubMed
4329.
OsbZIP72 plays a positive role in drought resistance through ABA signaling. (Mus musculus) PubMed
4330.
direct evidence that OsKO2 is involved in the sequential oxidation of ent-kaurene to ent-kaurenoic acid in gibberellin biosynthesis in rice [ent-kaurene oxidase 2] (Mus musculus) PubMed
4331.
Gain-of-function tests in transgenic rice and Arabidopsis thaliana showed that constitutive expression of GAP1 (GTPase-activating protein 1)led to increased resistance to bacterial pathogens in both monocots and dicots.[GAP1] (Mus musculus) PubMed
4332.
The defect of Os Phot1a affects degradation of chlorophylls and carotenoids, and under photosynthetically active photon fluxes, mutation of phot1a results in loss of photosynthetic capacity owing to the damage of photosystems.[Phot1a] (Mus musculus) PubMed
4333.
Transgenic rice plants overexpressing OsPIP1;3 showed an enhanced level of chilling tolerance. [OsPIP1;3] (Mus musculus) PubMed
4334.
These results indicate that OsGH3.1 overexpression reduces auxin content, inhibits cell growth and cell wall loosening, and enhances resistance to a fungal pathogen.[OsGH3.1] (Mus musculus) PubMed
4335.
These results suggest that ONAC045 encodes a novel stress-responsive NAC transcription factor and is potential useful for engineering drought and salt tolerant rice.(NAC) (Mus musculus) PubMed
4336.
Rcn1 is the first functionally defined plant ATP-binding cassette protein subfamily G protein gene that controls shoot branching and could thus be significant in future breeding for high-yielding rice.[Rcn1] (Mus musculus) PubMed
4337.
study clarified the biochemical & structural features of the DNA binding domain of RTBP1; results suggest helix 3 functions as a sequence-specific recognition helix while the N-terminal arm stabilizes the DNA binding [RTBP1; telomere binding protein 1] (Mus musculus) PubMed
4338.
The presence of two genes (Pi5-1, Pi5-2) is required for rice Pi5-mediated resistance to Magnaporthe oryzae.[Pi5-1; Pi5-2] (Mus musculus) PubMed
4339.
study describes the identification of Pi41, a major gene which contributes to the blast resistance of cultivar 93-11 [Pi41] (Mus musculus) PubMed
4340.
SP1 encodes a putative transporter of the peptide transporter family, which affects the panicle size of rice plants. [short panicle1] (Mus musculus) PubMed
4341.
OsVPE1 is a cysteine protease that plays a crucial role in the maturation of rice glutelins. [OsVPE1] (Mus musculus) PubMed
4342.
the expression of OsARGOS causes organ enlargement [ARGOS] (Mus musculus) PubMed
4343.
OsCAS could not interact with serine-acetyltransferase, indicating that OsCAS mainly functions in cyanide detoxification.[OsCAS] (Mus musculus) PubMed
4344.
In a jasmonate (JA)-deficient rice mutant, the photodestruction of phyA is delayed as shown by in vivo spectroscopy and Western blot analysis.[PhyA] (Mus musculus) PubMed
4345.
Three PUL-deficient mutants were generated to investigate the function of PUL in starch biosynthesis.[Pullulanase] (Mus musculus) PubMed
4346.
The OsHSF7 gene was found to be rapidly expressed in high levels in response to temperature, which indicates that it may be involved in heat stress reception and response.[OsHSF7] (Mus musculus) PubMed
4347.
Data showed that OsDof12 had transcriptional activity and the expression of OsDof12 was not tissue-specific and fluctuated at different development stages: [OsDof12] (Mus musculus) PubMed
4348.
OsWRKY24 is a novel type of transcriptional repressor that inhibits both gibberellin and abscisic acid signaling. [WRKY24] (Mus musculus) PubMed
4349.
The OPB gene encodes a transcription factor with a zinc finger motif, and is involved in the regulation of genes related to cellular proliferation and floral organ identity. [OPB] (Mus musculus) PubMed
4350.
Glucose suppressed the expression of ABA catabolism genes OsABA8ox3 and OsABA8ox2, which led to the delay of germination. [OsABA8ox2; OsABA8ox3] (Mus musculus) PubMed
4351.
Accumulation of the Rdd1 transcript is circadian clock-regulated, and has effects on the regulation of plant growth, flowering and grain size. [Rdd1] (Mus musculus) PubMed
4352.
OsATG10b plays an important role in the survival of rice cells against oxidative stresses.[OsATG10b] (Mus musculus) PubMed
4353.
DLT leads to decreased brassinosteroid responses, and is involved in feedback inhibition of brassinosteroid biosynthesis genes. [DLT] (Mus musculus) PubMed
4354.
OsNek3 is downstream of DCW11 in retrograde signaling from the mitochondria to the nucleus and is involved in cytoplasmic male sterility. [OsNek3] (Mus musculus) PubMed
4355.
ONAC063 may play an important role in eliciting responses to high-salinity stress.[ONAC063] (Mus musculus) PubMed
4356.
PLA3/GO encodes a glutamate carboxypeptidase II and is an ortholog of Arabidopsis AMP1 and maize VP8. [PLA3] (Mus musculus) PubMed
4357.
The transcription factor OsNAC4 is a key positive regulator of plant hypersensitive cell death (Mus musculus) PubMed
4358.
Metallothionein OsMT1a participates directly in ROS scavenging pathway and regulates expression of the zinc finger transcription factors via the alteration of Zn(2+) homeostasis, which leads to improved plant stress tolerance. [MT1a] (Mus musculus) PubMed
4359.
Grat was located to a region of 42.4 kb flanked by two microsatellite markers RM2-97 and RM13553. [grat] (Mus musculus) PubMed
4360.
STAR1 and STAR2 are expressed mainly in the roots, interact together to form a complex that functions as an ABC transporter, and are responsible for Al tolerance in rice. [2 genes, STAR1 and STAR2] (Mus musculus) PubMed
4361.
Data show that the expression of the OsPUL gene was maintained at a significant level during the entire grain filling period and in the late stage of seed germination, which coincided with its involvement in starch anabolism and catabolism: [OsPUL] (Mus musculus) PubMed
4362.
Results suggest that WOX11 may be an integrator of auxin and cytokinin signaling that feeds into RR2 to regulate cell proliferation during rice crown root development [WOX11]. (Mus musculus) PubMed
OsIAA1 may play important roles in the cross-talk of auxin and brassinosteroid signaling pathways and plant morphogenesis. [IAA1] (Mus musculus) PubMed
4365.
OsMYB3R-2 regulates the progress of the cell cycle during chilling stress. (Mus musculus) PubMed
4366.
OsDEG10 is a small RBP involved in the response to various abiotic stresses.(OsDEG10) (Mus musculus) PubMed
4367.
OsPLDbeta1 functions as a negative regulator of defense responses and disease resistance in rice. (Mus musculus) PubMed
4368.
[2 genes-virescent3 & stripe1] Virescent3 encodes the large subunit of the ribonucleotide reductase and is required for chloroplast biogenesis. Stripe1 encodes the small subunit of the ribonucleotide reductase and is required for chloroplast biogenesis. (Mus musculus) PubMed
4369.
Results identify the role of SHALLOT-LIKE1 (SLL1) in the modulation of leaf abaxial cell development and in sustaining abaxial characteristics during leaf development [SLL1]. (Mus musculus) PubMed
4370.
Race-specific pathogen-induced Xa13 expression is critical for infection. [Xa13] (Mus musculus) PubMed
4371.
OsSKIPa has evolved a specific function in positive modulation of stress resistance through transcriptional regulation of diverse stress-related genes in rice[ski-interacting protein ] (Mus musculus) PubMed
4372.
LAX1 protein is trafficked to the axillary meristem in a stage- and direction-specific manner. (Mus musculus) PubMed
4373.
The structures of the rice KARI-Mg(2+) and rice KARI-Mg(2)(+)-NADPH complexes to 1.55 A and 2.80 A resolutions, respectively, were determined. [KARI] (Mus musculus) PubMed
4374.
These results demonstrate roles for OsYSL15 in iron uptake and distribution in rice plants.[OsYSL15] (Mus musculus) PubMed
4375.
Overexpression of OsBIPP2C2a in transgenic tobacco plants resulted in enhanced disease resistance and constitutive expression of defense-related genes. [OsBIPP2C2] (Mus musculus) PubMed
4376.
The level of APO1 activity regulates the inflorescence form through control of cell proliferation in the meristem.[APO1] (Mus musculus) PubMed
4377.
PAIR3 functions in gametophyte development, and is required for chromosome pairing but not cytokinesis. [PAIR3] (Mus musculus) PubMed
4378.
Northern analysis showed that Isu1 was downregulated in iron-deficient rice root.[Isu1] (Mus musculus) PubMed
4379.
Both ef1 or ef1-h alleles can be used as new gene sources in developing rice varieties with extremely long basic vegetative growth periods for low latitudes.[Ef1] (Mus musculus) PubMed
4380.
study identified the erect-pose panicle (EP) candidate gene and elucidated its effects on several agronomic traits [EP] (Mus musculus) PubMed
4381.
results demonstrate rice synthesizes C-glucosylated flavones through the concerted action of a CGT and dehydratase acting on activated 2-hydroxyflavanones, as an alternative means of generating flavonoid metabolites[OSCGT] (Mus musculus) PubMed
4382.
Results show that expression of both plastidial methionine sulfoxide reductases, OsMSRA4.1 and OsMSRB1.1, are constitutively expressed in all organs and can be induced by various stress conditions: [OsMSRA4.1 and OsMSRB1.1] (Mus musculus) PubMed
4383.
ETR2 delays flowering and causes starch accumulation in stems by regulating downstream genes. (Mus musculus) PubMed
4384.
The AP37 gene has the potential to improve drought tolerance in rice without causing undesirable growth phenotypes. (Mus musculus) PubMed
4385.
SL1 positively regulates SPW1/OsMADs16, and is expressed at early flower developmental stages. [SL1] (Mus musculus) PubMed
4386.
NYC3 encodes a plastid-localizing alpha/beta hydrolase-fold family protein with an esterase/lipase motif, but does not show chlorophyll hydrolase activity. [NYC3] (Mus musculus) PubMed
4387.
OGR1 encodes a PPR protein of the DYW sub-group localized to mitochondria and is essential for mitochondrial RNA editing. [OGR1] (Mus musculus) PubMed
4388.
Transcriptional regulation of GAMYB has a role in anther development in rice. (Mus musculus) PubMed
4389.
Suppression of the 1d-myo-inositol 3-phosphate synthase gene, RINO1, varies within caryopses, which results in differences in phytic acid accumulation in transgenic seeds. [RINO1] (Mus musculus) PubMed
4390.
MER3 is required for normal meiotic crossover formation, but not for presynaptic alignment in rice. (Mus musculus) PubMed
4391.
DWARF27 (D27) is involved in the MAX/RMS/D pathway, in which D27 acts as a new member participating in the biosynthesis of strigolactones. (Mus musculus) PubMed
4392.
RISBZ1 and RPBF regulate seed storage protein gene expression, and positively regulate the aleurone layer number-related genes. [RISBF1; RPBF] (Mus musculus) PubMed
4393.
The expression patterns and functional properties of three rice HKT transporters, OsHKT1;1, OsHKT1;3, and OsHKT2;1, is reported.[OsHKT1, OsHKT2] (Mus musculus) PubMed
4394.
A newly detected mutant gene named ef7 confers an extremely long basic vegetative growth phase and increases photoperiod sensitivity.[ef7] (Mus musculus) PubMed
4395.
OsSSI2 is involved in the negative regulation of defense responses in rice. (Mus musculus) PubMed
4396.
Post-translational processing of glutelin is not necessary for trafficking and stable accumulation. [GluA2] (Mus musculus) PubMed
4397.
OsWRKY13-mediated signalling pathways are partitioned by different transcription factors. [WRKY13] (Mus musculus) PubMed
4398.
A spontaneous rice mutant, Epi-d1 showing a metastable dwarf phenotype, was identified.[DWARF1] (Mus musculus) PubMed
4399.
D14 encodes a protein of the alpha/beta-fold hydrolase superfamily, and functions downstream of strigolactone synthesis, as a component of hormone signaling. [D14] (Mus musculus) PubMed
4400.
Lsi1 mediates the uptake of undissociated methylated As in rice roots.[Lsi1] (Mus musculus) PubMed
4401.
The results uncover a new mechanism for light-regulated plant growth, namely, light not only inhibits cell elongation but also suppresses cell division through HAL3 and E3 ubiquitin ligase. [HAL3] (Mus musculus) PubMed
4402.
Results suggest that quantitative effect of light on flowering in night break is mediated by the regulation of Hd3a transcription by phyB: [phyB] (Mus musculus) PubMed
4403.
OsMADS50 and OsMADS56 function antagonistically in regulating long day-dependent flowering by controlling expression of OsLFL1 and Ehd1. [MADS50] (Mus musculus) PubMed
4404.
OsFCA protein interacts with a host of proteins including components involved in RNA processing. [OsFCA] (Mus musculus) PubMed
4405.
OsKCH1 is associated with cortical microtubules and actin microfilaments. [OsKCH1] (Mus musculus) PubMed
4406.
OsSPX1 may be a regulator involved in the transcriptions of OsSPX2, 3 and 5.[OsSPX1, OsSPX3] (Mus musculus) PubMed
4407.
HTD2 gene could negatively regulate tiller bud outgrowth by the strigolactone pathway.[HTD2] (Mus musculus) PubMed
4408.
D88, Dwarf88, represents a new category of genes that regulates cell growth and organ development and consequently plant: [D88] architecture. (Mus musculus) PubMed
4409.
OsBWMK1 may mediate salicylic acid-dependent defense responses by activating the OsWRKY33 transcription factor in plants. (OsBWMK1) (OsWRKY33) (Mus musculus) PubMed
4410.
Data show that over-expression of OsTIFY11a, one of the stress-inducible genes, resulted in significantly increased tolerance to salt and dehydration stresses: [OsTIFY11a] (Mus musculus) PubMed
4411.
Results indicate that OsTGAP1 functions as a key regulator of the coordinated transcription of genes involved in inductive diterpenoid phytoalexin production:[OsTGAP1] (Mus musculus) PubMed
4412.
A novel BR-induced rice gene BRASSINOSTEROID UPREGULATED1 (BU1), encoding a helix-loop-helix protein, is described.[BU1] (Mus musculus) PubMed
4413.
We identified three tandem W-box elements, putative recognition sites for WRKY transcription factors, as cis elements that are essential to the elicitor-responsiveness of OsWRKY53.[OsWRKY53] (Mus musculus) PubMed
4414.
ADL1 encodes a plant-specific calpain-like cysteine proteinase orthologous to maize. It plays an important role in pattern formation of the leaf and embryo by promoting proper epidermal development. ADL1 (Mus musculus) PubMed
4415.
Data show that a major and cold-induced thioredoxin h of rice, OsTrx23, has an inhibitory activity on stress-activated mitogen-activated protein kinases (MAPKs), OsMPK3 and OsMPK6 in vitro [mpk3, mpk6] (Mus musculus) PubMed
4416.
The s73 mutant displays early flowering and photoperiodic insensitivity due to a null mutation in the PHOTOPERIOD SENSITIVITY5 (SE5) gene, which encodes an enzyme implicated in phytochrome chromophore biosynthesis.[SE5] (Mus musculus) PubMed
4417.
TDD1 encodes an anthranilate synthase beta-subunit. Mutant plants exhibit decreased levels of Trp and indole acetic acid. [TDD1] (Mus musculus) PubMed
4418.
OsEF3 regulates heading date by influencing the basic vegetative growth stage and does not affect photoperiodic sensitivity. [EF3] (Mus musculus) PubMed
4419.
show the molecular mechanism of deepwater response through the identification of the genes SNORKEL1 and SNORKEL2, which trigger deepwater response by encoding ethylene response factors involved in ethylene signalling [SK1 & SK2] (Mus musculus) PubMed
4420.
OsNAC5 is a novel senescence-associated abscissic acid-dependent NAC transcription factor and its function could be related to Fe, Zn and amino acids remobilization from green tissues to seeds.[OsNAC5] (Mus musculus) PubMed
4421.
Both OsWRKY45-1- and OsWRKY45-2 are positive regulators in rice resistance against M. grisea, but the former is a negative regulator and the latter is a positive regulator in rice resistance against Xanthomonas.[OsWRKY45-1- and OsWRKY45-2] (Mus musculus) PubMed
4422.
SAUR39 acts as a negative regulator for auxin synthesis and transport.[SAUR39] (Mus musculus) PubMed
4423.
The morphology of the three phytochrome genes (PHYA, PHYB and PHYC) triple mutant seedlings grown under red or far-red light appears completely the same as etiolated seedlings, and they show no expression of the light-induced genes: [PHYA, PHYB, PHYC] (Mus musculus) PubMed
4424.
The over-expression of OsDREB1D conferred cold and high-salt tolerance in transgenic plants.[OsDREB1D] (Mus musculus) PubMed
4425.
cytosolic dihydroorotate dehydrogenase is involved in plant stress response and that OsDHODH1 could be used in engineering crop plants with enhanced tolerance to salt and drought[cytosolic dihydroorotate dehydrogenase (DHODH)] (Mus musculus) PubMed
4426.
ZFP245 may contribute to the tolerance of rice plants to cold and drought stresses by regulating proline levels and reactive oxygen species-scavenging activities.(ZFP245) (Mus musculus) PubMed
4427.
OsMADS14 is activated by FLOWERING LOCUS T 1 (RFT1) protein in the shoot apical meristem after the transition to flowering.[RFT1] (Mus musculus) PubMed
4428.
show that the FLORAL ORGAN NUMBER2 (FON2) SPARE1 (FOS1) gene encoding a CLE protein functions along with FON2 in maintenance of the floral meristem.[FLORAL ORGAN NUMBER2(FON2) and FON2 SPARE1] (Mus musculus) PubMed
4429.
KHA1 can be classified as an Na(+)/H(+) transporter [KHA1] (Mus musculus) PubMed
4430.
Two major K+ uptake systems were cloned and characterized. [TRK1p, HAK1p] (Mus musculus) PubMed
4431.
Alkyy hydroperoxide reductase plays a key role in adaption to high salinity by scavenging ROS, serving as chaperone and mediating H2O2-mediated defense signaling. [AHP] (Mus musculus) PubMed
4432.
NRG1 (GENBANK# DQ641949)mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans [Nrg1] (Mus musculus) PubMed
4433.
C. neoformans may have a limited requirement for Cch1 and that this requirement appears to include ion stress tolerance [cch1] (Mus musculus) PubMed
4434.
Four members of the C. neoformans (H99)catalase gene family were identified - CAT1 and CAT3 encode putative spore-specific catalases, CAT2 encodes a putative peroxisomal catalase, and CAT4 encodes a putative cytosolic catalase: CAT1, CAT2, CAT3 and CAT4. (Mus musculus) PubMed
4435.
Study shows that a Cryptococcus neoformans Hsp70 homologue Ssa1 is a DNA-binding transcriptional co-activator of laccase by binding to a GC-rich element within the 5'-UAS in response to glucose starvation, iron, copper, calcium and temperature. (Mus musculus) PubMed
4436.
results suggest that SXI1alpha and SXI2a coordinately control uniparental mitochondrial inheritance in C. neoformans [SXI1 alpha SXI2a] (Mus musculus) PubMed
4437.
Cdc24 is a Ras1 effector in C. neoformans to mediate the ability of this fungus to grow at high temperature and to cause disease [CDC24] (Mus musculus) PubMed
4438.
C. neoformans produces two GDP-mannose transporters to satisfy its enormous need for mannose utilization in glycan synthesis.[GMT1, GMT2] (Mus musculus) PubMed
4439.
Eca1 which encodes a sarcoplasmic/endoplasmic reticulum (ER) Ca2+-ATPase (SERCA)-type calcium pump is likely involved in maintaining ER function, thus contributing to stress tolerance and virulence acting in parallel with Ca2+-calcineurin signaling. (Mus musculus) PubMed
4440.
Based on the phenotype of dominant active alleles, Gpa2 and Gpa3 signal in opposition: Gpa2 promotes mating, whereas Gpa3 inhibits.[Gpa2, Gpa3] (Mus musculus) PubMed
4441.
Laccases utilizes both L- and D-DOPA at a similar rate in melanin synthesis. [Laccase] (Mus musculus) PubMed
4442.
Results show that the repression of EF3 led to the mislocalization of Cch1, suggesting a role for EF3 in targeting Cch1 to the plasma membrane of C. neoformans.[EF3,Cch1 in strain H99] (Mus musculus) PubMed
4443.
Deletion of PKC1 shows that this gene is essential for defense against both oxidative and nitrosative stresses; however, other genes involved directly in the PKC1 pathway are dispensable for protection against these stresses.[PKC1] (Mus musculus) PubMed
4444.
The authors conclude that Crg2 participates in controlling both Gpa1-cAMP-virulence and pheromone-mating signaling cascades.[Crg2 in strain CDX40] (Mus musculus) PubMed
4445.
In animal models the phenotype of the all1Delta mutant mimicked the hypervirulent phenotype of the mucoid switch variant, which is characterized by decreased host survival and elevated intracranial pressure.[ALL1] (Mus musculus) PubMed
4446.
The crystal structure of Can2 reveals that the enzyme belongs to the "plant-type" beta-carbonic anhydrase (CAs) but carries a unique N-terminal extension that can interact with the active-site entrance of the dimer.[Can2] (Mus musculus) PubMed
4447.
Subcellular localization ras1 protein dictates its downstream signaling specificity. [Ras1] (Mus musculus) PubMed
4448.
The authors showed that the AFR1-overexpressing mutant strain was not sensitive to microglia-mediated anticryptococcal activity, as compared with the wild type and the afr1Delta mutant.[AFR1 in strain BPY22] (Mus musculus) PubMed
4449.
Disruption of CUF1 demolished the activation of LAC1 transcription by copper, whereas the reconstituted strain restored the phenotypic defects.[CUF1] (Mus musculus) PubMed
4450.
Deletion of vtc4 in U. maydis reduced proliferation in host plants and polyphosphate (polyP) stored in vacuoles revealing a novel role for PKA-regulated polyP accumulation in fungal morphogenesis and virulence [vtc4p] (Mus musculus) PubMed
4451.
Biz1 is involved in cell cycle arrest preceding plant penetration as well as in the induction of appressoria. (Mus musculus) PubMed
4452.
The Clp1 protein facilitates cell cycle progression during hyphal growth. [CLP1] (Mus musculus) PubMed
4453.
Don3 kinase exerts a dual function in the regulation of cell separation and nuclear envelope breakdown [Don3] (Mus musculus) PubMed
4454.
cooperation between BRC and CRE domains and the Dss1-provoked dissociation of Brh2 complexes are requisite features of Brh2's molecular mechanism [Dss1][Brh2] (Mus musculus) PubMed
4455.
Cdk5 is essential for growth, maintenance of cell polarity, and full virulence in U. maydis [Cdk5] (Mus musculus) PubMed
4456.
These results suggest that U. maydis is using its Yap1-controlled H(2)O(2) detoxification system for coping with early plant defense responses.[Yap1] (Mus musculus) PubMed
4457.
the role of the putative U. maydis BCCIP ortholog Bcp1 in DNA repair and recombination (Mus musculus) PubMed
4458.
Rad52 serves in an overlapping, compensatory role with both Rec2 and Brh2 to promote and maintain formation of the Rad51 nucleoprotein filament.[Rad52] (Mus musculus) PubMed
4459.
In vitro GDP/GTP exchange assays demonstrated that Don1 is highly specific for Cdc42 and cannot activate Rac1.[Don1, Cdc42] (Mus musculus) PubMed
4460.
fuz1 is necessary for cell morphogenesis of the Ustilago maydis. [Fuz1] (Mus musculus) PubMed
4461.
This study revealed that transcriptional regulation of prf1 had only minor influence on target gene expression stressing the importance of post-translational control.(Prf1) (Mus musculus) PubMed
4462.
Absence of Spa2 does not affect cytoskeleton organization and pathogenicity.[Spa2] (Mus musculus) PubMed
4463.
Bem1 and Cdc24 physically interact and colocalize at cell tips and that Cdk5 regulates this interaction.[Bem1, Cdc24, Cdk5] (Mus musculus) PubMed
4464.
Endosomal compartmentalization of a Cdc42-specific exchange factor is involved in the coordination of cytokinesis and cell separation.[Don1] (Mus musculus) PubMed
4465.
Lga2 in conjunction with Rga2 directs uniparental mtDNA inheritance by mediating loss of the a1-associated mtDNA.[lga2][rga2] (Mus musculus) PubMed
4466.
Rep1-1 filaments decrease in length at increasing concentrations[Rep1] (Mus musculus) PubMed
4467.
Brh2 can pair the displaced strand of a D loop with a complementary single-stranded DNA to form a duplexed, or double, D loop. (Mus musculus) PubMed
4468.
The expression of ena1 and ena2 transcripts in U. maydis was enhanced at high pH and at high K(+) and Na(+) concentrations. [ENA1, ENA2] (Mus musculus) PubMed
4469.
The rok1 dual specificity MAPK phosphatase regulates the activity of Kpp2 as well as of Kpp6. [Rok1] (Mus musculus) PubMed
4470.
The a2 mating-type-locus gene lga2 of Ustilago maydis interferes with mitochondrial dynamics and fusion, partially in dependence on a Dnm1-like fission component. (Mus musculus) PubMed
4471.
The authors identified the Ustilago maydis gene, cco1, encoding a putative beta-carotene cleavage oxygenase. (Mus musculus) PubMed
4472.
Spe-Sdh mutants were sensitive to stress, unable to carry out the yeast-to-mycelium dimorphic transition, and showed attenuated virulence to maize.[Spe-Sdh] (Mus musculus) PubMed
4473.
Template switching promoted by Brh2 provides a mechanism for recombination-mediated bypass of lesions blocking synthesis during DNA replication.[Brh2] (Mus musculus) PubMed
4474.
A single Candida albicans transcription factor gene UPC2 that regulates sterol metabolism. (Mus musculus) PubMed
4475.
Residue of H310 was important to the function of CYP51. [CYP51] (Mus musculus) PubMed
4476.
results suggest that Ecm33p is required for normal cell wall architecture as well as normal function and expression of cell surface proteins in C. albicans [ecm33] (Mus musculus) PubMed
4477.
This involvement of SST2 in the sensitivity to pheromone is consistent with the prediction that the mating response pathway in C. albicans requires the activation of a heterotrimeric G protein [SST2] (Mus musculus) PubMed
4478.
Tac1p is a transcription factor regulating CDR1 and CDR2, and its mutation is associated with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans [Tac1p, CDR2] (Mus musculus) PubMed
4479.
the fungal pathogen Candida albicans carries an 899-residue stress-inducible orthologue of Hsp104 (CaHsp104) that shows a high degree of amino acid identity to S. cerevisiae Hsp104 [Hsp104] (Mus musculus) PubMed
4480.
identification and disruption of RAC1, and show that, in contrast to CDC42, it is not necessary for viability or serum-induced hyphal growth but is essential for filamentous growth when cells are embedded in a matrix [rac1 & cdc42] (Mus musculus) PubMed
4481.
N-acetylglucosamine-phosphate mutase (AGM1) was purified and crystallized. The crystals diffract X-rays to beyond 1.8 angstroms resolution using synchrotron radiation. (AGM1) (Mus musculus) PubMed
4482.
two ORFs, CaFAD2 & CaFAD3, were identified based on homology to other yeast fatty acid desaturases; results strongly supported that CaFAD2 encodes the Delta12 fatty acid desaturase and that CaFAD3 encodes the omega3 fatty acid desaturase [FAD2, FAD3] (Mus musculus) PubMed
4483.
C. albicans Ssa2p facilitates fungicidal activity of Hst 5 in binding and intracellular translocation, whereas Ssa1p appears to have a lesser functional role in Hst 5 toxicity [Ssa1p, Ssa2p] (Mus musculus) PubMed
4484.
These results support the hypothesis that the Grr1 protein of C. albicans, presumably as the F-box subunit of an SCF ubiquitin ligase, has an essential role in preventing the switch from the yeast cell morphology to a pseudohyphal morphology.[GRR1] (Mus musculus) PubMed
4485.
PDR16 plays a role in C. albicans azole resistance.(PDR16) (Mus musculus) PubMed
4486.
Multiple transcription factors control expression of the MDR1 efflux pump and mutations that cause constitutive MDR1 overexpression and drug resistance affects the activities of several of these transcription factors. [MDR1] (Mus musculus) PubMed
4487.
results indicate that CaBud6 plays an important role in the polarized growth of C. albicans [Bud6] (Mus musculus) PubMed
4488.
BCR1 pathway functions in vivo to promote biofilm formation; known adhesin Hwp1 also contributes to biofilm formation [BRC1 and Hwp1] (Mus musculus) PubMed
4489.
The resistant strains experimentally induced after fluconazole exposure in vitro were associated mainly with up-regulation of ERG11 gene. [ERG11] (Mus musculus) PubMed
4490.
an essential role for the conserved Ras association (RA) domain-mediated Ras1-Cdc35 interaction in raising cellular cAMP levels for hyphal morphogenesis [CDC35, RAS1] (Mus musculus) PubMed
4491.
simple model can account for both the heritability of the white and opaque states and the stochastic nature of the switching between them [Wor1] (Mus musculus) PubMed
4492.
present genetic evidence for feedback regulation of WOR1 transcription[WOR1] (Mus musculus) PubMed
4493.
Fcy21 is efficient high-affinity, high-capacity, purine transporter equal to AzgA from Aspergillus nidulans (Fcy21). (Mus musculus) PubMed
4494.
alanyl-tRNA synthetase has evolved an unusual pattern of translation initiation and protein partitioning and codes for protein isoforms that can aminoacylate isoaccepting tRNAs from a different species and from across cellular compartments [ALA1] (Mus musculus) PubMed
4495.
the TR region of Als5p modulated the structure of the Ig-T region, augmented cell adhesion activity through increased binding to mammalian ligands, and simultaneously promoted fungal cell-cell interactions.[Als5] (Mus musculus) PubMed
4496.
findings show that Cka2p governs the interactions of C. albicans with endothelial and oral epithelial cells in vitro and virulence during oropharyngeal candidiasis [casein kinase II subunit alpha] (Mus musculus) PubMed
4497.
TOS9, exhibited an expression pattern consistent with a "master switch gene." TOS9 was only expressed in opaque cells, and its gene product, Tos9p, localized to the nucleus.[Tos9] (Mus musculus) PubMed
4498.
Endogenous Rim101 directly binds to the alkaline-pH-repressed gene PHR2, and the activity is governed not only by proteolytic processing but also by an additional mechanism not previously described: Rim101. (Mus musculus) PubMed
4499.
Results identify a novel protein that interacts with CaTup1p, named Tcc1p (Tup1p complex component) [Tcc1] (Mus musculus) PubMed
4500.
Deletions of VPS28 and VPS32 increase the susceptibility of C. albicans to cell wall disruption agents, echinocandin and azole antifungal agents. [Vps32] (Mus musculus) PubMed
4501.
the Vac1p protein is required for several cellular pathways, in particular those that control virulence and pathogenicity. [Vac1p] (Mus musculus) PubMed
4502.
This finding provides additional support for the model that Hwp1 is critical for biofilm adhesion. (Mus musculus) PubMed
4503.
In this study, the role of amino acid residues in the Ssk1p receiver domain was investigated by constructing point mutants at positions of protein phosphorylation [Ssk1p] (Mus musculus) PubMed
4504.
Cap1 has a significant role in redox status regulation, energy metabolism and substance transport (Cap1). (Mus musculus) PubMed
4505.
These results implicate Drg1p in the control of invasive filamentation in the laboratory, and in the progression of invasive disease in the host.[DRG1] (Mus musculus) PubMed
4506.
characterization of the cis-acting regulatory elements present in the MDR1 promoter [MDR1] (Mus musculus) PubMed
4507.
Proteomic comparison of plasma membrane proteins from buds and from hyphae induced by GlcNAc identified a novel hyphal protein (Ngt1) with similarity to the major facilitator superfamily of transporters. (Mus musculus) PubMed
4508.
These studies are the first to identify proteins that bind to a DNA segment that confers developmental gene regulation in C. albicans and suggest a new model for hypha-specific gene regulation.[Hwp1, Nhp6, Gcf1p] (Mus musculus) PubMed
4509.
Study identified and characterized a functional Candida albicans homolog (CaTCO89) of ScTCO89, which encodes a protein of 708 amino acids that shows overall 15% identity with ScTco89p at the amino acid level.[TCO89 protein] (Mus musculus) PubMed
4510.
We report here that the DNA helicase Hmi1p plays a crucial role in mtDNA stability in Candida albicans. [CaHm1p] (Mus musculus) PubMed
4511.
C. albicans invades mucosal tissues by promoting the proteolytic degradation of E-cadherin in epithelial adherens junctions, mediated by transcription factor Rim101 and Sap5 proteins. [Rim101, Sap5] (Mus musculus) PubMed
4512.
The role of two previously uncharacterized Rho proteins, encoded by the Candida albicans RHO3 (CaRHO3) and CaCRL1/CaRHO4 genes, is investigated.[Rho3, Rho4] (Mus musculus) PubMed
4513.
These results demonstrate that the GATA transcription factors GLN3 and GAT1 control expression of the MEP2 ammonium permease and that GLN3 is also an important regulator of nitrogen starvation-induced filamentous growth in C. albicans.[Mep2, Gln3, Gat1] (Mus musculus) PubMed
4514.
These data suggest that DOA1 of C. albicans, like its orthologue in S. cerevisiae, is associated with ubiquitin-mediated proteolysis and has multiple functions. [DOA1 protein] (Mus musculus) PubMed
4515.
Results illustrate an association between Eap1p-mediated adhesion and biofilm formation in vitro and in vivo [Eap1]. (Mus musculus) PubMed
4516.
CaAbp1 and CaPan1 were found to localize at the cortex and at hyphal tips in a patch-like manner, supporting their role in endocytosis [Abp1, Pan1] (Mus musculus) PubMed
4517.
Structural comparison with previously determined structures of the enzyme.ligand complexes of other orthologue allowed modeling of the binding of four different inhibitors into the active site of lumazine synthase from Candida albicans [lumazine synthase] (Mus musculus) PubMed
4518.
homozygous null mutant in a mouse model of systemic candidiasis displayed strongly reduced pathogenicity compared with parental or heterozygous strains. [ATC1] (Mus musculus) PubMed
4519.
It was found that a C. albicans fatty acid desaturase homolog (Ole2) and a multicopper oxidase homolog (Fet3) play roles in prostaglandin production. [Fet3] (Mus musculus) PubMed
4520.
Data demonstrate functional homology of Hmt1 between C. albicans and S. cerevisiae: CaHmt1 supports growth of S. cerevisiae strains that require Hmt1, and CaHmt1 methylates Npl3, a major Hmt1 substrate, in S. cerevisiae [Hmt1]. (Mus musculus) PubMed
4521.
For the yeast prion Sup35, we find that the switch to the prion state is controlled with exquisite specificity by small elements of primary sequence [Sup35] (Mus musculus) PubMed
4522.
These results reveal that C. albicans hyphal development occurs through Sec3p-independent and dependent phases, and provide strong genetic and biochemical evidence for a role of septins in polarized exocytosis. (Mus musculus) PubMed
4523.
VPS4 is required for vacuolar biogenesis and proper sorting of vacuolar proteins [VPS4, no strain name] (Mus musculus) PubMed
4524.
They knocked out both alleles of an ortholog of BCR1, a gene encoding a transcription factor known to be required for biofilm development in C. albicans. They show that C. parapsilosis BCR1 is necessary for biofilm development in C. parapsilosis (Mus musculus) PubMed
4525.
Cargt1 mutations cause cells to hyperfilament, and suppress the hypofilamented phenotype of an hgt4 mutant, indicating that the Hgt4 glucose sensor may affect filamentation by modulating sugar import and metabolism via CaRgt1.[Rgt1] (Mus musculus) PubMed
4526.
The effects of the deletion of PDE2 is investigated by genome-wide transcriptome profiling. (Mus musculus) PubMed
4527.
ALS5 alleles had 2-10 tandem repeat sequence copies while ALS6 alleles had 2-8 copies: [ALS5] and [ALS6] (Mus musculus) PubMed
4528.
One gene, upregulated in both reconstituted human oral epithelium infection and patients, named EED1, was essential for maintenance of hyphal elongation.[EED1] (Mus musculus) PubMed
4529.
Candida albicans yeast forms deleted for ALS5, ALS6 or ALS7 are more adherent than a relevant control strain to human vascular endothelial cell monolayers and buccal epithelial cells. [ALS5, ALS6, ALS7] (Mus musculus) PubMed
4530.
Results provide evidence that Cdc28/Hgc1 may act to prevent Rga2 from localizing to hyphal tips, leading to localized Cdc42 activation for hyphal extension [Rga2, Hgc1]. (Mus musculus) PubMed
4531.
This study of Gfa1p focuses on the features that distinguish it from the prokaryotic homologue in terms of quaternary structure, control of the enzymatic activity and details of the isomerase active site.[Gfa1] (Mus musculus) PubMed
4532.
Sfl1 is a negative regulator of hyphal development in C. albicans. (Mus musculus) PubMed
4533.
A connection between actin structures and the cAMP signaling pathway was shown using hyper- and hypomorphic cAMP mutants, providing a possible mechanism for up-regulation of HWP1 gene expression by stabilized actin.[HWP1] (Mus musculus) PubMed
4534.
The HOG stress response pathway likely represents a significant and effective challenge to physiological levels of Hst 5 and other toxic peptides in fungal cells.[Hog1] (Mus musculus) PubMed
4535.
These results suggest that Sfl1 functions in the repression of flocculation and filamentation and thus represents a novel negative regulator of C. albicans morphogenesis.[Sfl1] (Mus musculus) PubMed
4536.
CZF1 binds CZF1 promoter DNA in vitro and promotes the switch from white to opaque. [CZF1] (Mus musculus) PubMed
4537.
Ssk2 is the sole MAPKKK to relay stress signals to Hog1 in C. albicans [Hog1, Ssk2 and Pbs2] (Mus musculus) PubMed
4538.
Sun41 is required for biofilm formation and normal caspofungin tolerance. Sun41 is required for inducing disease.[Sun41] (Mus musculus) PubMed
4539.
Results show that PDR16 expression in Candida albicans was controlled by zinc cluster transcription factor Tac1p [PDR16 and Tac1p] (Mus musculus) PubMed
4540.
These results show that Tac1p binds under nonactivating conditions to the promoters of its targets, including to its own promoter.[Tac1] (Mus musculus) PubMed
4541.
Here, we demonstrate that the Rim101/PacC pH-sensing pathway acts in parallel to Crz1, via calcineurin, to adapt to alkaline pH. [Rim101, Crz2, calcineurin] (Mus musculus) PubMed
4542.
results suggest that MET6 is essential, and a double deletion is lethal [MET6] (Mus musculus) PubMed
4543.
GLN3 was an activator of two genes involved in ammonium assimilation, GDH3, encoding NADP-dependent glutamate dehydrogenase, and MEP2, which encodes an ammonium permease. [GLN3 in strain CAI-4] (Mus musculus) PubMed
4544.
the surface-expressed CaGpm1p is a virulence factor that utilizes the host Factor H, FHL-1, and plasminogen for immune evasion and degradation of extracellular matrices [CaGpm1p] (Mus musculus) PubMed
4545.
Site-directed mutagenesis indicates that T929G (Gly310Val) substitution is responsible for the non-functionality of the encoded enzyme.[HIS4 in strain CAI-4] (Mus musculus) PubMed
4546.
we have identified a zinc cluster transcription factor, designated as MRR1 (multidrug resistance regulator), that was coordinately upregulated with MDR1 in drug-resistant, clinical C. albicans isolates. (Mus musculus) PubMed
4547.
the main function of ascomycetous Sun proteins appears linked to cell wall remodelling, with a probable role in counter-balancing cell wall degradation to avoid cell lysis upon cell separation.[SUN41, SUN42] (Mus musculus) PubMed
4548.
Our data clearly show that both ergosterol and sphingolipids are essential for selectively recruiting CaDCr1p, over CaMdr1p, to the membrane rafts and that any imbalance in the raft lipid constituents results in missorting of CaCdr1p. [Cdr1p, Mdr1p] (Mus musculus) PubMed
4549.
Expression of EFH1 regulated the level of colonizing fungi, favoring commensalism as opposed to candidiasis. (Mus musculus) PubMed
4550.
Large fragments of Als5p contained the conserved amyloid-forming sequence and it formed amyloid-like fibers and bound Congo red under native conditions.[Als5] (Mus musculus) PubMed
4551.
Deletion mutation was used to determine the role of SSK2 and it was found to be involved in osmotic and oxidative stress.[SSK2] (Mus musculus) PubMed
4552.
Study reports the characterization of the three predicted Carnitine acetyltransferases genes in C. albicans, CTN1, CTN2 and CTN3.[CTN1, CTN2, CTN3] (Mus musculus) PubMed
4553.
The effect of deleting G-protein-coupled receptor 1 (GPR1) and trehalose-6-phosphate (T6P) phosphatase (TPS2) on the virulence of C. albicans in mice is reported.[GPR1; TPS2] (Mus musculus) PubMed
4554.
Our results demonstrate that both increased CDR1 transcription and enhanced CDR1 mRNA stability contribute to the overexpression of CDR1 in azole resistant C. albicans isolates. (Mus musculus) PubMed
4555.
The X-ray crystal structures of the apoenzyme of Sap1 and Sap5 in complex with pepstatin A at 2.05 and 2.5 A resolution are reported.(Sap1)(Sap5) (Mus musculus) PubMed
4556.
Upc2p is a key regulator of ergosterol metabolism. (Mus musculus) PubMed
4557.
These results reveal that the eIF5B in Candida albicans has a close functional relationship with that of Sacharomyces cerevisiae, as also shown by a phylogenetic analysis based on the amino acid sequences of the eIF5Bs.[eIFB] (Mus musculus) PubMed
4558.
protein kinase Psk1 is required for expression of SKO1 and of Sko1-dependent genes in response to caspofungin [Psk1] (Mus musculus) PubMed
4559.
Rbt5and Rbt51 facilitate the rapid endocytosis of haemoglobin into the C. albicans vacuole. [Rbt5, Rbt51] (Mus musculus) PubMed
4560.
HSP12 is regulated by CO2 via a cAMP-dependent mechanism.[hsp12] (Mus musculus) PubMed
4561.
CCAAT binding factor (CBF) is essential for FRP1 expression in iron-limited environments and FRE2 and FRP1 are both induced directly by the Rim101 transcription factor [CBF, FRP1,FRP2,Rim101] (Mus musculus) PubMed
4562.
The present findings provide evidence that DDR48 is essential for filamentation, stress response, and possibly viability of C. albicans.[DDR48] (Mus musculus) PubMed
4563.
These results demonstrate that mutations in MRR1 are the major mechanism of MDR1 overexpression in fluconazole-resistant strains and that MRR1 plays a central role in the development of drug resistance in C. albicans.(MRR1) (Mus musculus) PubMed
4564.
Rac1 activation by the guanine nucleotide exchange factor Dck1 is required for invasive filamentous growth in the pathogen Candida albicans [Dck1, Rac1] (Mus musculus) PubMed
4565.
Loss of Kar3p led to defects in nuclear division, causing cells to grow slowly and exhibit reduced viability compared to wild-type cells. [Kar3] (Mus musculus) PubMed
4566.
The disruption of RTA2 increased the susceptibility of C. albicans to azoles. (RTA2) (Mus musculus) PubMed
4567.
The presence of an inorganic phosphate in the crystallographic structure opposite the known AMP binding site relative to the thiamine moiety suggests that a second AMP molecule could be accommodated in the C. albicans structure.[TPK] (Mus musculus) PubMed
4568.
MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans (Mus musculus) PubMed
4569.
Galpha and Gbeta subunits do not act antagonistically but, instead, are both required for the transmission of the mating signal. [Cag1, Ste4] (Mus musculus) PubMed
4570.
present the crystal structure of GGTase-I from C. albicans (CaGGTase-I) in complex with its cognate lipid substrate, geranylgeranylpyrophosphate[geranylgeranyltransferase-I alpha and beta subunit] (Mus musculus) PubMed
4571.
C-terminal signals regulate the protein targeting of Ecm331 and Hwp1 to the cell wall or plasma membrane. [Ecm331, Hwp1] (Mus musculus) PubMed
4572.
RTA2 is involved in calcineurin-mediated azole resistance and sphingoid long-chain base release in C. albicans. (Mus musculus) PubMed
4573.
Complement receptor 3 related protein (CR3-RP) has immunomodulatory properties and a role in the adherence of Candida albicans in vitro (using the model systems of buccal epithelial cells) and biofilm formation. [CR3-RP] (Mus musculus) PubMed
4574.
C. albicans cells lacking the superoxide dismutase Sod5 leads to massive extracellular reactive oxygen species accumulation in vitro, and mutants lacking Sod5 and Sod4 exhibit a severe loss of viability in the presence of macrophages. [Sod4; Sod5] (Mus musculus) PubMed
4575.
These results suggest that Delta8-desaturation of long-chain bases in ceramides plays a role in the morphogenesis of C. albicans.[delta8-desaturase] (Mus musculus) PubMed
4576.
In this study the authors demonstrate that ferric reductase FRP1 expression is upregulated by alkaline pH and iron-limited conditions.[FRP1 in strain DAY1] (Mus musculus) PubMed
4577.
Phenotypic analysis of a methionine-regulated conditional mutant confirmed that Abg1p is involved in endocytosis.[ABG1] (Mus musculus) PubMed
4578.
findings support models in which Tor1 negatively controls cellular adhesion by governing the activities of Bcr1 and Efg1[Tor1] (Mus musculus) PubMed
4579.
Hog1 mutants show an enhanced respiratory rate and higher levels of intracellular reactive oxygen species.[Hog1] (Mus musculus) PubMed
4580.
a three-dimensional model of the C. albicans Met6p based on the known structure of the homologous enzyme from Arabidopsis thaliana was created. (Mus musculus) PubMed
4581.
Our resutls indicate that Gcf1 protein is a a nonspecific DNA-binding protein involved in mtDNA replication and recombination and thus in fine-tuning mtDNA metabolism. [Gcf1] (Mus musculus) PubMed
4582.
The iff4 Delta null mutant showed both a decrease of adherence to silicone catheter and a reduction of virulence.[iff4] (Mus musculus) PubMed
4583.
Bmh1 mutants showed attenuated virulence in a mouse model. [Bmh1] (Mus musculus) PubMed
4584.
Opposite roles for Tpk1 and Tpk2 isoforms were observed in glycogen storage, suggesting that each of the isoforms has different substrates involved in glycogen regulation. (TPK1) (TPK2) (Mus musculus) PubMed
4585.
Increased expression generally accompanies Cap1p binding at its targets, indicating that Cap1p functions as a transcriptional activator.[Cap1] (Mus musculus) PubMed
4586.
Study of crystal structures of the editing domain from 2 eukaryotic cytosolic LeuRS; shows a conserved structural core containing the active site for hydrolysis, with distinct bacterial, archeal, or eukaryotic peripheral insertions.[LeuRS] (Mus musculus) PubMed
4587.
Rep1p is involved in drug resistance by negatively regulating MDR1 in C. albicans.[Regulator of Efflux Pump 1/REP1] (Mus musculus) PubMed
4588.
The C. albicans zinc-response transcription factor Zap1 is a negative regulator of a major matrix component, soluble beta-1,3 glucan, in both in vitro and in vivo biofilm models.[Zap1] (Mus musculus) PubMed
4589.
These data suggest that Chk1p and Sho1p are components of parallel but independent signal pathways.[Chk1] (Mus musculus) PubMed
4590.
Overexpressing CaSwi1 mitigated invasive and pseudohyphal growth defects resulting from deletions in the MAP kinase and cAMP pathways.[Swi1] (Mus musculus) PubMed
4591.
The authors show that Cek1 phosphorylation is regulated by quorum sensing. (Mus musculus) PubMed
4592.
Auxotrophy of strain S4B3008 is due to a mutation of the ADE5 gene encoding a phosphoribosylamine-glycine ligase. (ADE5) (Mus musculus) PubMed
4593.
The reconstitution of Gibberella zeae PKS13, which is the nonreducing PKS associated with zearalenone biosynthesis, is reported.[PKS13] (Mus musculus) PubMed
4594.
Putative pheromone precursor genes (ppg1 and ppg2) and their corresponding pheromone receptor genes (pre2 and pre1) were identified in the genomic sequence of G. zeae. [pre2, pre1, ppg1, ppg2] (Mus musculus) PubMed
4595.
SNF1 is critical for normal sexual and asexual development in addition to virulence and the utilization of carbon sources. [SNF1] (Mus musculus) PubMed
4596.
data show that one of the mechanisms conferring in vitro-induced benznidazole resistance to T. cruzi correlates with deletion of copies of the TcOYE gene [OYE] (Mus musculus) PubMed
4597.
The identification and characterization of TcrPDEB1 and its comparison with the previously identified TcrPDEB2 (formerly known as TcPDE1), is reported. (Mus musculus) PubMed
4598.
Tc-1 is a cell surface casein kinase II (CKII) substrate expressed only in invasive trypomastigotes, phosphorylated by human CKII and involved in the early process of cellular infection. (Tc-1) (Mus musculus) PubMed
4599.
identification, expression, purification, enzyme kinetics, and the role of divalent metal in the ATPase activity of the RNA triphosphatase from Trypanosoma cruzi and compares it with the enzyme from Trypanosoma brucei [RNA triphosphatrase] (Mus musculus) PubMed
4600.
TcSPPS is a solanesyl-diphosphate synthase localizes in glycosomes of Trypanosoma cruzi [TcSPPS] (Mus musculus) PubMed
4601.
Our findings show an increased expression of the TcFeSOD-A enzyme in the T. cruzi population with in vitro-induced resistance to benznidazole. (FeSOD-A) (Mus musculus) PubMed
4602.
The isolation of phospholipase A1 (Plase A1) from Trypanosoma cruzi infective stages and its possible role regarding the interaction with mammalian host cells are reported.[phospholipase A1] (Mus musculus) PubMed
4603.
overexpression of mitochondrial iron superoxide dismutase, which is also observed during metacyclogenesis, resulted in cytoprotective effects[iron superoxide dismutase] (Mus musculus) PubMed
4604.
isolation and characterization of a new member of the gp82 family and global analysis on the expression as well as the cellular localization of gp82 proteins in metacyclic forms of the CL and G strains [Gp82] (Mus musculus) PubMed
4605.
In the case of Tc-SAHH, the final affinity for NAD+ is roughly micromolar and this affinity persists as the equilibrium affinity.[S-adenosylhomocysteine hydrolase] (Mus musculus) PubMed
4606.
The D80A mutation induces only a slight conformational change in the active site yet results in a significant alteration of nucleotide binding and modifies the ability of the dUTPAse to discriminate between dUTP and dUMP (dUTPase). (Mus musculus) PubMed
4607.
In summary, we found that few strains can express different isoforms of Amastigote Surface Protein 2 (ASP-2) which may not share cross-protective epitopes. [ASP-2] (Mus musculus) PubMed
4608.
Complementation experiments showed that the intact calmodulin-ubiquitin (cub) gene is necessary for full expression of virulence [cub] (Mus musculus) PubMed
4609.
Can utilize both L-galactono-gamma-lactone and D-arabinono-gamma-lactone as substrates for synthesis of vitamin C. (galactonolactone oxidase; galactonolactone dehydrogenase; GLDHase) (Mus musculus) PubMed
4610.
We demonstrated that three subfamilies of gp82 were in the genome of T. cruzi and maintained their functional structure, and that the mRNA expressions of those genes were equally controlled in a stage-specific manner.[pg82] (Mus musculus) PubMed
4611.
The unfolding transition of triosephosphate isomerase was found to be highly irreversible even at the very early stages of the reaction(triosephosphate isomerase). (Mus musculus) PubMed
4612.
The compartmentalization switch of LYT1 results in two surprisingly different functions: haemolytic activity at acid pH for mLYT1, and a putative involvement in mitochondrial metabolism for kLYT1.[LYT1] (Mus musculus) PubMed
4613.
Study reports the cloning, expression, purification, and characterization of the exopolyphosphatase TcPPX gene The product of this gene, has 383 amino acids and a molecular mass of 43.1 kDa.[PPX] (Mus musculus) PubMed
4614.
To define similarities and differences with the human pair, we performed a detailed alanine scan analysis that allowed us to identify the regions and the critical amino acids of T. cruzi SF3b155 involved in interaction with p14[SF3b155] (Mus musculus) PubMed
4615.
This study was conducted to characterize the infective behavior of the LYT1 deletion stratin, T. cruzi L16, in the insect vector and murine models.[LYT1] (Mus musculus) PubMed
4616.
TcPUF6 regulates the half-lives of its associated transcripts via differential association with mRNA degradation complexes throughout its life cycle[PUF6] (Mus musculus) PubMed
4617.
Results describe the expression of markers on dendritic cells from chronic chagasic patients stimulated with the KMP-11 protein and the K1 peptide from Trypanosoma cruzi [Kmp-11]. (Mus musculus) PubMed
4618.
Results describe polymorphisms in the genes in Colombian strains of Trypanosoma cruzi [trypanothione reductase, cruzipain]. (Mus musculus) PubMed
4619.
The crystal structure of dihydroorotate dehydrogenase (DHODH) from T. cruzi strain Y solved at 2.2A resolution was reported. (Mus musculus) PubMed
4620.
The binding of NAD (+) and NADH in SAHH appears structurally to be mediated by helix 18, formed by seven residues near the C-terminus of the adjacent subunit [SAHH] (Mus musculus) PubMed
4621.
first detailed characterization of the Trypanosoma cruzi actin [actin] (Mus musculus) PubMed
4622.
study reports the purification, partial biochemical characterization and subcellular localization of a T. cruzi secreted 75 kDa serine oligopeptidase from the axenic epimastigote forms [75 kDa serine oligopeptidase] (Mus musculus) PubMed
4623.
The role of complement C2 receptor inhibitor trispanning gene (CRIT) in the resistance of 2 strains of T. cruzi to complement-mediated lysis is reported.[CRIT] (Mus musculus) PubMed
4624.
TcVps34 plays a prominent role in vital processes for T. cruzi survival such as osmoregulation, acidification, and vesicular trafficking[TcVps34] (Mus musculus) PubMed
4625.
Our findings demonstrate increased expression of the cytosolic and mitochondrial Tryparedoxin peroxidase (TXNPx) in the T. cruzi population with in-vitro-induced resistance to benznidazole. (Mus musculus) PubMed
4626.
TcCRT participates in the induction of cardiac autoimmunity in Chagas' disease.[calreticulin] (Mus musculus) PubMed
4627.
TcSBDS contains a C-terminal extension of 200 amino acids that displays the features of intrinsically disordered proteins as determined by proteolytic, circular dichroism and NMR analyses. (TcSBDS, accession number EU715774) (Mus musculus) PubMed
4628.
As papain exhibits high structural similarity to the catalytic domain of the T. cruzi enzyme cruzipain, the present chagasin-papain complex provides a reliable model of chagasin-cruzipain interactions[chagasin] (Mus musculus) PubMed
4629.
These findings strongly support a key role for classical and novel protein kinase C isoenzymes in the signaling pathways involved in Trypanosoma cruzi metacyclogenesis induced by oleic acid.[protein kinase C in strain RA] (Mus musculus) PubMed
4630.
The dynamics of Tc38 subcellular localization observed during the cell cycle and life stages support a major role for Tc38 related to kDNA replication and maintenance.[Tc38] (Mus musculus) PubMed
4631.
These results show that GP63 is expressed at all life stages and that individual isoforms play a role in host cell infection. (Mus musculus) PubMed
4632.
The interaction between U2AF35 and U2AF65 was very weak or not detectable. However, as in other eukaryotes, the interaction between U2AF65 and SF1 was strong.[U2AF35,U2AF65 and SF1] (Mus musculus) PubMed
4633.
Dispersed Gene Family-1 (DGF-1) members, comprising the third largest T. cruzi specific gene family, have conserved adhesin motifs including four segments with significant similarity to human beta 7 integrin [Dispersed Gene Family-1] (Mus musculus) PubMed
4634.
KAP4 and KAP6 exhibit differential distribution in the kinetoplast of distinct developmental stages. [KAP4;KAP6] (Mus musculus) PubMed
4635.
These data demonstrate that prozyme mediated activation of S-adenosylmethionine decarboxylase is a common mechanism required to regulate S-adenosylmethionine decarboxylase activity in the trypanosomatids.[prozyme] (Mus musculus) PubMed
4636.
characterization of SHSP16;recombinant SHSP16 showed molecular chaperone activity in vitro [SHSP16] (Mus musculus) PubMed
4637.
Preliminary X-ray analysis of aspartate transcarbamoylase from Trypanosoma cruzi at 2.8 A resolution, is reported.[Aspartate transcarbamoylase] (Mus musculus) PubMed
4638.
The data show that the establishment of a disulfide bridge between two C202 of two dimeric Triosephosphate isomerase from the mesophile Giardia lamblia, accounts for multimerization. (Mus musculus) PubMed
4639.
The crystal structures of the apo and Ca(2+)-bound forms of alpha-11 giardin, the first alpha giardin to be characterized structurally, is reported.[alpha-11 giardin] (Mus musculus) PubMed
4640.
isolated as an approximately 35-kDa polypeptide, which was identified by mass spectrometry as a nitroreductase (NR) homologue (EAA43030.1). [GLNR1] (Mus musculus) PubMed
4641.
The solution structure of a distant variant of ubiquitin, found at the N-terminus of S27a in Giardia lamblia, referred to as GlUb(S27a), is reported.[GlUb(S27a)] (Mus musculus) PubMed
4642.
The only NST of Giardia (GlNst), which we could identify, transports UDP-GlcNAc in transfected Saccharomyces and is present in perinuclear and peripheral vesicles and increases in expression during encystation. [NST (nucleotide sugar transporter)] (Mus musculus) PubMed
4643.
Giardia cysteine protease 2 is not only the major cysteine endoprotease expressed in Giardia, but is also central to the encystation process [CP2] (Mus musculus) PubMed
4644.
These findings reveal a dual role played by ADI and define novel regulatory pathways used by Giardia for survival.[ADI] (Mus musculus) PubMed
4645.
Alpha-14 giardin exhibits calcium-dependent binding to phospholipids that coordinate cytoskeletal disassembly/assembly during differentiation of the parasite.[Annexin E1] (Mus musculus) PubMed
4646.
specificity of the oxygen-detoxifying flavodiiron protein towards O2 [flavodiiron protein] (Mus musculus) PubMed
4647.
Overexpression of ehcp5 but not of ehcp1 or ehcp2 significantly increased amoebic liver abscess formation in laboratory animals supporting the important role of EhCP5 in E. histolytica pathogenicity.[Cysteine proteinase CP5] (Mus musculus) PubMed
4648.
Expression of a negative dominant version of EhGEF2 protein in E. histolytica provoked a 30% decrease in its ability to phagocyte human erythrocytes as well as severe effects on both the proliferation and the cellular chemotaxis[GEF2] (Mus musculus) PubMed
4649.
we report the molecular cloning, from E. histolytica genomic DNA, of the genes ehtrxr and ehtrx41, respectively coding for thioredoxin reductase (EhTRXR) and thioredoxin (EhTRX41). EhTRXR)(EhTRX41) (Mus musculus) PubMed
4650.
This protein, alpha-actinin2, has a N-terminal actin-binding domain, a C-terminal calcium-binding domain and an intervening rod domain containing two spectrin repeats.[alpha-actinin2] (Mus musculus) PubMed
4651.
Entamoeba Arp2 complements analogous Dictyostelium mutations at all stages of the life cycle [arp2] (Mus musculus) PubMed
4652.
unfolding and refolding of the Triose phosphate isomerase from Entamoeba histolytica (Mus musculus) PubMed
4653.
Results provide insight into the structure of Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase [GAPDH]. (Mus musculus) PubMed
4654.
PAK3 protein from E. histolytica has constitutive activity and has demonstrated a strong involvement in receptor capping (EhPAK3). (Mus musculus) PubMed
4655.
The lgl4 and -5 subunits (31 kDa) are overexpressed and appear to compensate for the missing lgl1 to -3 in the heterodimer complex.[Lgl4, Lgl5] (Mus musculus) PubMed
4656.
EhSTIRP thus likely represents a novel determinant of virulence in Entamoeba histolytica.[EhSTIRP] (Mus musculus) PubMed
4657.
Here we show recombinant EhNst2 (nucleotide-sugar transproter) transports UDP-Glc in transfected Giardia, while recombinant EhNst3 transports UDP-GlcNAc in transfected Saccharomyces. [EhNsSt2, EhNst3] (Mus musculus) PubMed
4658.
The crystal structure of native O-acetyl-serine sulfhydrylase (OASS) from Entameoba histolytica has been determined at 1.86 A resolution and in complex with its product cysteine at 2.4 A resolution.(OASS) (Mus musculus) PubMed
4659.
results implicate rhomboid proteases for the first time in immune evasion and suggest that a common function of rhomboid enzymes in widely divergent protozoan pathogens is to break down adhesion proteins.[ROM1 protein (rhomboid protease)]. (Mus musculus) PubMed
4660.
Our results show that a CD59-like molecule is expressed in trophozoites of E. histolytica found in colonic amebic lesions. [CD59] (Mus musculus) PubMed
4661.
This gene has a 154 bp intron and encodes for a highly conserved polypeptide. {Ehvma2} (Mus musculus) PubMed
4662.
Functional studies of nucleotide exchange of Phe314Ala GEF1 mutant showed a decrement of 80% on RacG GTPase.[GEF1] (Mus musculus) PubMed
4663.
The 3D structure of EhCaBP2 was determined using multidimensional NMR; the protein consists of two globular domains connected by a short flexible linker region of four residues [CaBP2] (Mus musculus) PubMed
4664.
Oxidase and reductase activities were shown in the protein disulfide isomerase of Entamoeba histolytica. [PDI] (Mus musculus) PubMed
4665.
cloned, expressed and purified thymidine kinase (Eh-TK) and uridine-cytidine kinase (Eh-UCK). inhibitors or alternate substrates, although partially reduce protozoan proliferation, are reversible [thymidine kinase and uridine-cytidine kinase; no strain] (Mus musculus) PubMed
4666.
MLBP binds preferentially to the methylated forms of DNA target. [MLBP] (Mus musculus) PubMed
4667.
These studies demonstrate that PbKch1 contributes to the transport of K(+) in P. berghei parasites and supports the growth of the parasites, in particular the development of oocysts in the mosquito midgut.[Kch1] (Mus musculus) PubMed
4668.
Study shows that a novel, protein, termed TRAP-like protein (TLP), is a functional members of the TRAP family; TLP is expressed in invasive stages, targeted gene disruption revealed a nonvital role during life cycle progression.[TLP] (Mus musculus) PubMed
4669.
asparagine-rich protein is a key regulator of Plasmodium sporozoite gene expression and LS development[SLARP] (Mus musculus) PubMed
4670.
The authors demonstrate that the sporozoite-specific transmembrane protein S6 is required for efficient malaria transmission to the vertebrate host.[S6] (Mus musculus) PubMed
4671.
UBP-1 (deubiquinating enzyme) gene mutations in artesunate- and chloroquine-resistant rodent malaria parasites. [UBP-1] (Mus musculus) PubMed
4672.
Genetic polymorphism in T-helper cell epitopic regions of circumsporozoite protein of 148 Plasmodium falciparum isolates from different epidemic and endemic regions of India [circumsporozoite protein] (Mus musculus) PubMed
4673.
findings suggesting that most malaria in pregnancy arises from parasite adhesion to chondroitin sulfate A in association with expression of the unique epitopes of VAR2CSA[VAR2CSA] (Mus musculus) PubMed
4674.
crystal structure of beta-hydroxyacyl acyl carrier protein dehydratase of Plasmodium falciparum (PfFabZ) has been determined at a resolution of 2.4 A [FabZ] (Mus musculus) PubMed
4675.
A study evaluating the synthetic substrate and model inhibitor profiles of FP-2 and FP-3 as well as BP-2 (berghepain-2), an orthologue from the rodent parasite Plasmodium berghei, is presented. (Mus musculus) PubMed
4676.
Plasmodium falciparum histidine-rich protein II reduces CD69 expression in T cells. [Plasmodium falciparum histidine protein II] (Mus musculus) PubMed
4677.
The heparin binding site of TRAP-TSR domain is located in the N-terminal half of the structure. The smallest heparin fragment binding to TRAP-TSR is a tetrasaccharide.(Thrombospondin-related anonymous protein) (Mus musculus) PubMed
4678.
PfORC1 is expressed specifically in the nucleus during the trophozoite and schizont stages of the asexual parasitic life cycle where maximum amount of DNA replication takes place. [ORC1] (Mus musculus) PubMed
4679.
cloning, overexpression, and characterization of three members of the heat shock family, PfHsp70-1 (an Hsp70 protein with a C-terminal EEVD motif), PfHsp70-2 (an Hsp70 protein without the EEVD motif), and PfHsp70 interacting protein[PfHsp70-1, PfHsp70-2] (Mus musculus) PubMed
4680.
Gene is not amplificied in Plasmodium falciparum isolated from Guinea-Bissau and Liberisa. [pfmdr1 protein] (Mus musculus) PubMed
4681.
His-509-Glu-514 dyad, in analogy to those in related oxidoreductases, acts as the acid-base catalyst in Pf thioredoxin reductase [thioredoxin reductase] (Mus musculus) PubMed
4682.
Pfnek3 was able to phosphorylate and stimulate Pfmap2; the Pfnek3-Pfmap2 interaction may be specific for Pfmap2 regulation(Pfnek3)(Pfmap2) (Mus musculus) PubMed
4683.
results suggest that P. falciparum requires expression of falstatin to limit proteolysis by certain host or parasite cysteine proteases during erythrocyte invasion (Mus musculus) PubMed
4684.
The interaction of Plasmodium falciparum EBA-181 with the highly conserved 10 kDa domain of 4.1R provides new insight into the molecular mechanisms utilized by P. falciparum during erythrocyte entry [EBA-181] (Mus musculus) PubMed
4685.
Primary processing of merozoite surface protein 7 (MSP7) occurs prior to that of MSP1 in a post-Golgi compartment, whereas the secondary cleavage occurs on the surface of the developing merozoite[merozoite surface protein 7} (Mus musculus) PubMed
4686.
Raf kinase inhibitor protein is recognized as a substrate under in vitro conditions and appears to act as a regulator of calcium-dependent protein kinase 1 kinase activity[Raf kinase inhibitor protein and calcium-dependent protein kinase 1] (Mus musculus) PubMed
4687.
Study found that the N-terminal 24 amino acids of RhopH2, including signal peptide sequence, were sufficient to target green fluorescent protein to the rhoptries under the rhoph2 promoter. [RhopH2] (Mus musculus) PubMed
4688.
expression, purification, and characterization of a falcipain-1 construct encoding mature falcipain-1 and 35 amino acids from the C-terminal of the pro domain; results suggest a possible role of falcipain-1 in merozoite invasion [falcipain-1] (Mus musculus) PubMed
4689.
In these samples from Venezuela, there is a single origin and fixation for both dhfr(dihydrofolate reductase) and dhps (dihydropteroate synthase) Sulfadoxine-Pyrimethamine-resistant alleles. [Dhfr, Dhps] (Mus musculus) PubMed
4690.
The homologue of mammalian UCHL3 was cloned from both T. gondii and Plasmodium falciparum and it was shown that both enzymes possess deubiquitinating as well as deNeddylating activity.[UCHL3 protein] (Mus musculus) PubMed
4691.
In this study, a higher level of diversity at microsatellite (MS) loci within the pfcrt gene was observed when compared with the level of diversity at pfcrt flanking MS (Mus musculus) PubMed
4692.
Pfs48/45 protein consists of a C-terminal six-cysteine module recognized by anti-epitope I antibodies, a middle four-cysteine module recognized by anti-epitopes IIb and III, and an N-terminal module recognized by anti-epitope V antibodies [pfs48/45] (Mus musculus) PubMed
4693.
2.4-A and 2.7-A structures of P. falciparum aldolase (PfAldo), obtained from crystals grown in the presence of the C-terminal hexapeptide of TRAP from Plasmodium berghei, are described.[Aldolase] (Mus musculus) PubMed
4694.
Results suggest that PfGCN5 is recruited to the promoter regions of genes to mediate histone acetylation and activate gene expression in P. falciparum [PfGCN5]. (Mus musculus) PubMed
4695.
The mechanism deduced by product inhibition studies proves that PfLDH shares a common mechanism with the human LDHs, that of an ordered sequential bireactant system with coenzyme binding first.[lactate dehydrogenase] (Mus musculus) PubMed
4696.
Significant sequence polymorphism was found within repeat regions of PfRh1, PfRh2a, and PfRh2b [PfRH1] (Mus musculus) PubMed
4697.
the transition-state structures of PfADA, HsADA, and bovine ADA (BtADA) solved using competitive kinetic isotope effects (KIE) and density functional calculations [ADA] (Mus musculus) PubMed
4698.
Migration of parasites carrying an ancestral triple-mutant dhfr allele drives the spread of dhfr alleles associated with pyrimethamine resistance throughout West and Central Africa.[dihydrofolate reductase] (Mus musculus) PubMed
4699.
there is no promiscuous transcription of var genes at the individual cell level,and it is possible to correlate dominant transcripts with adhesion phenotype and clinical markers of malaria severity [var] (Mus musculus) PubMed
4700.
data demonstrate that stage specific promoter activity of the hrp3 gene in P. falciparum blood stage parasites is supported, at least in-part, by a small promoter region that can function in the absence of a larger chromosomal context[hrp3] (Mus musculus) PubMed
4701.
var gene transcription was analysed in patients dying with falciparum malaria.[var] (Mus musculus) PubMed
4702.
Lipoproteins, especially those of the low-density lipoprotein fraction, promote PfEMP1 surface presentation. (Mus musculus) PubMed
4703.
Data suggest that Pfmap-2 is essential for the asexual cycle of P. falciparum, but that Pfmap-1 is not necessary for schizogony and gametocytogenesis in erythrocytes, nor for gametogenesis and sporogony in the mosquito vector [Pfmap-1, -2]. (Mus musculus) PubMed
4704.
The role of Pfnek3 as a likely upstream MAPK kinase is defined through molecular and biochemical characterization.[Pfnek3] (Mus musculus) PubMed
4705.
MAEBL.The M2 domain was sequenced from lab isolates and African samples. No evidence of diversifying or positive selection was found in the pattern of base substitutions. (Mus musculus) PubMed
4706.
The effect of MSP2 polymorphism of P. falciparum on the severity of malaria infections is reported.[MSP2] (Mus musculus) PubMed
4707.
This study shows that PfSir2 has the appropriate characteristics to be a direct regulator of chromatin structure in P. falciparum.[Sir2] (Mus musculus) PubMed
4708.
The gene encoding this channel is termed P. falciparum aquaglyceroporin and is a single-copy gene and highly homologous to other aquaporins from other protozoa; only two non-synonymous mutations were found in 65 strains.[AQP] (Mus musculus) PubMed
4709.
point mutations occur in the dhfr and dhps genes and the presence of combinations of three alleles in dhfr (51Ile, 59Arg and 108Asn) and "quintuple" mutant (dhfr 51Ile, 59Arg, 108Asn and dhps 437Gly, 540Glu). (Mus musculus) PubMed
4710.
NMR chemical shift perturbation analysis mapped the location of the possible ferredoxin-NADP(+) reductase interaction sites on the surface of ferredoxin(ferredoxin-NADP(+) reductase, ferredoxin). (Mus musculus) PubMed
4711.
Both P. falciparum protein, reticulocyte homology 4 (PfRH4) and a recombinant protein bind strongly to neuraminidase-treated erythrocytes. (Mus musculus) PubMed
4712.
The substrate recognition mechanism as well as the rearrangement of the hydrogen bond array at the active site for orotidine 5'-monophoshate decarboxylase were determined (Orotidine 5'-monophoshate decarboxylase). (Mus musculus) PubMed
4713.
Used x-ray crystal structure of Plasmodium falciparum dihydrofolate reductase (DHFR) to select antimalarials for future high-throughput screening experiments. (Mus musculus) PubMed
4714.
Release of merozoites from schizonts resulted in the movement of rhomboid-1 protease from the lateral asymmetric localization to the merozoite apical pole and the posterior pole[rhomboid-1 protease] (Mus musculus) PubMed
4715.
In P. falciparum the para-Nitrophenyl Phosphatase capable to catalyse thiamine monophosphate phosphatase reaction has been identified by analysis of the substrate specificity.[para-Nitrophenyl Phosphatase] (Mus musculus) PubMed
4716.
Localisation studies show that LplA2 is present in both mitochondrion and apicoplast of Plasmodium falciparum. (Mus musculus) PubMed
4717.
investigation of PfATPase6 gene polymorphism in seventy-five P. falciparum isolates from imported malaria cases in Italy, originating in various endemic areas throughout the world [ATPase6] (Mus musculus) PubMed
4718.
complex interplay of domain-domain communication & nonactive-site modulation of catalysis in P. falciparum TS-DHFR. parasitic TS-DHFR is activated by mechanisms, modulated by their nonactive site regions[thymidylate synthase-dihydrofolate reductase] (Mus musculus) PubMed
4719.
These results suggest that secreted PfHMGB1 (high mobility group box protein 1) and PfHMGB2 may be responsible for eliciting/ triggering host inflammatory immune responses associated with malaria infection. [HMGB1, HMBG2] (Mus musculus) PubMed
4720.
The active conformation of protein kinase 7 is stabilized by a structural motif in which the role of the conserved phosphorylated residue that assists in structuring the activation loop is played by an arginine residue (protein kinase 7). (Mus musculus) PubMed
4721.
wild-type histoaspartic protease (HAP), H34A and S37A were strongly inhibited by the serine protease inhibitor phenylmethanesulfonyl fluoride[histoaspartic protease] (Mus musculus) PubMed
4722.
Native data sets extending to 1.9 A resolution have been collected and phasing is under way[var2csa and EMP1] (Mus musculus) PubMed
4723.
show the production of a properly folded Pfs48/45 C-terminal fragment by simultaneous coexpression with four periplasmic folding catalysts in Escherichia coli[Pfs48/45] (Mus musculus) PubMed
4724.
These results indicate a role of TRAP-Like Protein (TLP) in cell traversal by sporozoites [TLP]. (Mus musculus) PubMed
4725.
Pfdpm1 represents a unique enzyme among subgroups compared in this study.(Pfdpm1) (Mus musculus) PubMed
4726.
findings show that PfATP6 is a more diverse gene than previously demonstrated [ATP6] (Mus musculus) PubMed
4727.
VAR2CSA appears to be a major ligand for placental adhesion.[var2csa] (Mus musculus) PubMed
4728.
strong association between pfcrt , but not pfmdr1 86Y mutation and in vivo chloroquine resistance [pfcrt] (Mus musculus) PubMed
4729.
Binding of TRAP to SH3-domain containing proteins like Src-family kinases and their ability to phosphorylate PfTRAP suggests a novel role for TRAP in cell signaling during sporozoite invasion and homing inside the liver cells. [Trap] (Mus musculus) PubMed
4730.
MSP2 associates with lipid micelles, but predominantly through the N-terminal region rather than the C terminus, which is GPI-anchored to the membrane in the parasite. (Mus musculus) PubMed
4731.
These data demonstrate a role for central memory T cells in natural malarial immunity and support current vaccination strategies aimed at inducing durable protective T cell responses against the TRAP antigen.[TRAP] (Mus musculus) PubMed
4732.
Compared with the human enzyme, the recombinant P. falciparum thymidylate kinase showed a broader spectrum of substrate specificity (thymidylate kinase). (Mus musculus) PubMed
4733.
Collectively, these findings point towards an essential role for the PfTSN in the parasite's infection cycle.[Plasmodium falciparum Tudor Staphylococcal Nuclease (PfTSN)] (Mus musculus) PubMed
4734.
Plasmodium telomeres might fold back and that Orc1 cooperates with Sir2 in telomeric silencing [Orc1] (Mus musculus) PubMed
4735.
The experiments did not reveal significant changes in var2CSA levels and chondroitin sulfate A-binding capacity.[var2CSA in strain 193CSA] (Mus musculus) PubMed
4736.
The bacterial histone-like protein exhibits DNA binding and is capable of condensing DNA (bacterial histone-like protein). (Mus musculus) PubMed
4737.
a limited genetic polymorphism of the P126 OR domain does not seem to influence the development of a specific humoral immune response to P126 [P126 antigen (Sera or SERP)] (Mus musculus) PubMed
4738.
New insight into Plasmodium falciparum chloroquine resistance transporter {PFCRT) function and, along with previous results, proposing a model for a single chloroquine binding site. (Mus musculus) PubMed
4739.
Lack of MSP7 was not lethal at the asexual blood stage, but it impair the invasion of erythrocytes by merozoites. [MSP7] (Mus musculus) PubMed
4740.
Genetic analyses of Reticulocyte Binding protein PfRh2b reveal that the entire cytoplasmic tail and the conserved motif within the cytoplasmic tail are indispensable for invasion Plasmodium falciparum. (Mus musculus) PubMed
4741.
Pf332 both modulates the level of increased red blood cell(RBCs) rigidity induced by Plasmodium falciparum and plays a significant role in adhesion by assisting transport of PfEMP1 to the infected RBC surface[ Pf332 ] (Mus musculus) PubMed
4742.
We heterologously coexpressed AK2 and P. falciparum N-myristoyltransferase (NMT) in the presence of myristate in Escherichia (Mus musculus) PubMed
4743.
Reverse genetics in the rodent malaria model, Plasmodium berghei, suggests that profilin is essential for the invasive blood stages of the parasite. [profilin] (Mus musculus) PubMed
4744.
The Pf332 DBL domain conformed to the generic pattern for DBL domains. Pf332 is not involved in cytoadhesion or merozoite invasion. [Pf332] (Mus musculus) PubMed
4745.
The occurrence of mutations was investigated in the pfmdr1 (N86Y) and pfcrt (K76T) genes, associated with CQ resistance, as well as in pfdhfr (C59R), pfdhps (K540E), conferring sulphadoxine-pyrimethamine resistance. (pfmdr1)(pfcrt)(pfdhfr)(pfdhps) (Mus musculus) PubMed
4746.
There was a correlation only between Pfs 16 cDNA overexpression in the first 48h of the culture and the production of mature gametocytes. Pfs 16 is an early marker of the development of mature gametocytes in cultures [Pfs16] (Mus musculus) PubMed
4747.
high-resolution atomic force microscopy revealed non-linear asymmetric structures, with beaded domains and flexible loops that were recognized predominantly as dimers, although monomers and larger multimers were observed[MSP3, FVO strain] (Mus musculus) PubMed
4748.
spatial orientation of domains of the heat shock protein 70 from Plasmodium falciparum and the protein's chaperone function (Mus musculus) PubMed
4749.
Stx1 is the first identified vesicular trafficking component localized proximal to the P. falciparum plasma membrane.[Stx1] (Mus musculus) PubMed
4750.
Parasites with the PfRh2b deletion were found to preferentially utilize protease-resistant pathways for erythrocyte invasion[PfRh2b, new isolate] (Mus musculus) PubMed
4751.
Kinase activity was markedly affected by introducing a larger lysine residue instead of A111 and the lack of a hydroxyl group after inducing mutation of Y107F affected enzyme activity [TMP kinase, strain not indicated] (Mus musculus) PubMed
4752.
Parasite recrudescences in 33 consecutive paired episodes during the same pregnancy were identified by msp1 and msp2 [msp1,msp2] (Mus musculus) PubMed
4753.
sequenced the complete HDP gene encompassing three exons and two introns from five P. falciparum lab strains with known CQ sensitivity and 50 field isolates from Venezuela and Kenya, with high levels of CQ resistance [heme detoxification protein] (Mus musculus) PubMed
4754.
The presence of three or more copies of pfmdr1 were associated with recrudescence in artesunate-mefloquine treated patients [Pfmdr1] (Mus musculus) PubMed
4755.
results suggest that saglin/TRAP interaction is crucial for salivary gland invasion by Plasmodium sporozoites [TRAP] (Mus musculus) PubMed
4756.
MAHRP-1 specifically interacts with erythrocyte membrane through a 20-mer-long amino acid region, raising questions about this region's potential as a therapeutic target against malaria.(MAHRP-1) (Mus musculus) PubMed
4757.
The N-terminus but not the C-terminus of REX2 is important for export. A single-point mutation in the N-terminus abolishes export. [REX2] (Mus musculus) PubMed
4758.
PfNapL has unique histone binding properties [PfNapL] (Mus musculus) PubMed
4759.
The P. falciparum PfATPase gene is polymorphic at the 569 codon (Mus musculus) PubMed
4760.
first report implicating an heterochromatin protein 1 protein in the control of antigenic variation of a protozoan parasite (heterochromatin protein 1). (Mus musculus) PubMed
4761.
The presented results demonstrate that reduction in the mobility of this region in Pdx1 proteins is required for formation of the in vivo dodecamer, negatively affecting the activity of Pdx1, opening the possibility of allosteric Pdx1 inhibitors.[Pdx1] (Mus musculus) PubMed
4762.
Nhe-1 polymorphism was significantly associated with reduced quinine susceptibility. [Nhe-1] (Mus musculus) PubMed
4763.
In the apoenzyme crystals, HAP forms a tight dimer not seen previously in any aspartic protease.[HAP] (Mus musculus) PubMed
4764.
These findings indicate that genetically CQ-resistant P. falciparum are more common than previously thought in Madagascar even though the fitness of the minority variant pfcrt 76T parasites remains unclear (Mus musculus) PubMed
4765.
reports variation in C-terminal region of MSP-1 from P falciparum isolates from southern Iran [MSP-1] (Mus musculus) PubMed
4766.
analysis of the interactions of curcumin with PfATP6 (Mus musculus) PubMed
4767.
present work represents the first evidence for functional interactions between the PfHsp70-1 and Pfj1 [Hsp70-1] (Mus musculus) PubMed
4768.
The isolation and characterization of protein arginine N-methyltransferase 1 (PRMT1) in Plasmodium falciparum is reported.[PRMT1] (Mus musculus) PubMed
4769.
A study on the metal ion binding characteristics of recombinant P. falciparum M17 leucine aminopeptidase (rPfLAP) shows that the active site of this exopeptidase contains two metal-binding sites. (Mus musculus) PubMed
4770.
pfnhe contributes to QN resistance[sodium-proton exchanger PfNHE] (Mus musculus) PubMed
4771.
the 40 residue C-terminal domain of MSP3 protein self-assembles into a four-stranded alpha-helical coiled coil structure where alpha-helices are packed "side-by-side" [no strain specified; merozoite surface protein 3] (Mus musculus) PubMed
4772.
Evidence is provided that one of the novel eIF2alpha kinases, PfeIK1, is able to phosphorylate the P. falciparum eIF2alpha orthologue in vitro [PfeIK1 and eIF2alpha] (Mus musculus) PubMed
4773.
study reports structure of the gene that encodes PfRON4 & its apparent limited diversity amongst geographically diverse P. falciparum isolates; also report that PfRON4 protein sequences elicit immunogenic responses in natural malaria infections[PfRON4] (Mus musculus) PubMed
4774.
A structural model of pro-falcipain-2 was constructed by homology modeling based on crystallographic structures of mature falcipain-2, procathepsin K, procathepsin L, and procaricain.[Falcipain-2] (Mus musculus) PubMed
4775.
A functional nek-2 gene is required for transmission of both Plasmodium falciparum and the rodent malaria parasite Plasmodium berghei to the mosquito vector.[Nek-2] (Mus musculus) PubMed
4776.
monomerdimer interconversion of ferredoxin-NADP+ reductase can be controlled by oxidizing and reducing agents that are possibly present within the apicoplast, such as H(2)O(2), glutathione, and lipoate.[ferredoxin--NADP reductase] (Mus musculus) PubMed
4777.
Immunofluorescence studies with antibodies to functional ferrochelatase reveal that the native enzyme is localized to the mitochondrion of the parasite indicating that this organelle is the ultimate site of heme synthesis.[ferrochelatase] (Mus musculus) PubMed
4778.
Despite vast diversity, restricted disease-associated var genes were identified and might be used for innovative interventions based on erythrocyte membrane protein-1.[EMP1] (Mus musculus) PubMed
4779.
These findings suggest that the two arginine residues surrounding T121 are critical for the binding specificity of BAEBL (VSTK) to sialic acid and suggest a role for arginine in sialic acid binding independent of its negative charge.[BAEBL] (Mus musculus) PubMed
4780.
Kinetic data in combination with expression result support the proposal of serine hydroxymethyltransferase reaction being a regulatory step for dTMP cycle.[serine hydroxymethyltransferase] (Mus musculus) PubMed
4781.
potential in vivo regulation of Pfnek3, with residues T82, S221 and S226 functioning as phospho-activating sites.[Pfnek3] (Mus musculus) PubMed
4782.
Substrate of glyoxalase II is predominantly bound via ionic interactions with the conserved residues Arg(257) and Lys(260), and that correct substrate binding is a pH- and salt-dependent rate-limiting step for catalysis. [glyoxalase II] (Mus musculus) PubMed
4783.
The above observations suggest that the antibody response against RAP-2/RSP-2 and other members of the complex could trigger the destruction of RAP-2/RSP-2-tagged host cells.[RAP2] (Mus musculus) PubMed
4784.
DBL6 epsilon domain of VAR2CSA binds to placental chondroitin sulfate proteoglycans through a positively charged surface on the distal side of subdomain 2 that is exposed in intact VAR2CSA on the erythrocyte surface.[VAR2CSA] (Mus musculus) PubMed
4785.
The immune reaction of adults and children to liver stage antigen 1 (LSA-1) and thrombospondin-related adhesive protein (TRAP) among adults and children are reported.[LSA-1; TRAP] (Mus musculus) PubMed
4786.
1 amino acid substitution was responsible not only for PyEBL localization but also the erythrocyte-type invasion preference of the parasite and subsequently its virulence in mice[erythrocyte ligand or EBL] (Mus musculus) PubMed
4787.
The distribution of TaSE during mitosis makes it a protein to consider as playing a potential role for parasite distribution into daughter host cells. [TaSE] (Mus musculus) PubMed
4788.
These experiments suggest that ACE1 appressorium-specific expression does not depend on host plant signals but is connected to the onset of appressorium-mediated penetration. [ACE1 protein] (Mus musculus) PubMed
4789.
These data indicate that the MAPK-docking site of Mst7 is essential for its association and activation of downstream Pmk1, and the Mst7-Pmk1 interaction is enhanced or stabilized during appressorium formation. [Mst7, Pmk1] (Mus musculus) PubMed
4790.
Rgs1 regulates multiple Galpha subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism. [Rgs1] (Mus musculus) PubMed
4791.
These observations suggest that Con7p encodes a transcription factor required for the transcription of several genes which participate in disease-related morphogenesis in M. grisea.[Con7p] (Mus musculus) PubMed
4792.
Results describe the involvement of a Magnaporthe grisea serine/threonine kinase gene, MgATG1, in appressorium turgor and pathogenesis [Atg1]. (Mus musculus) PubMed
4793.
MIR1 is an M. grisea-specific gene that is highly conserved among the field isolates belonging to the M. grisea species complex; mir1 mutants had no obvious defects in appressorial penetration and rice infection. [Mir1 gene] (Mus musculus) PubMed
4794.
The snodprot1 homolog MSP1 is required for virulence. (Mus musculus) PubMed
4795.
Two superoxide-generating NADPH oxidase-encoding genes, Nox1 and Nox2, are independently required for pathogenicity of M. grisea. [Nox1 & Nox2 NADPH oxidase] (Mus musculus) PubMed
4796.
Cut2 is therefore required for surface sensing leading to correct germling differentiation, penetration, and full virulence in this model fungus.[Cutinase2] (Mus musculus) PubMed
4797.
The data suggests that ABC4 is required for the pathogenicity of M. grisea, helping the fungus to cope with the cytotoxic environment during infection.[ABC4] (Mus musculus) PubMed
4798.
EGL1 endoglucanase from Magnaporthe grisea was characterized [EGL1] (Mus musculus) PubMed
4799.
The mig1 deletion mutant had a normal growth rate and formed melanized appressoria, but it was nonpathogenic and failed to infect rice leaves through wounds.[mig1] (Mus musculus) PubMed
4800.
[ACE1] The avirulence gene ACE1 from the rice blast fungus Magnaporthe grisea encodes a polyketide synthase (PKS) fused to a nonribosomal peptide synthetase (NRPS). (Mus musculus) PubMed
4801.
The results demonstrate that MgLig4 is involved in, but not essential for, the non-homologous end-joining system.[MGLIG4 in strain Guy11] (Mus musculus) PubMed
4802.
study focuses on expression analysis, recombinant production and biochemical characterization of intracellular catalase/peroxidase of M. grisea (MagKatG1); [MagKatG1] (Mus musculus) PubMed
4803.
interactions between Rac1 and PAK kinase Chm1 are responsible for conidiogenesis, and between Rac1 and NADPH oxidases Nox1 and Nox2 are important for pathogenicity [Rac1][Chm1] (Mus musculus) PubMed
4804.
PMK1 gene sequence is homologous to MAPK gene. So are their functions. (Mus musculus) PubMed
4805.
The authors conclude that MgCRZ1 is essential for growth, development, and full virulence of Magnaporthe grisea.[CRZ1] (Mus musculus) PubMed
4806.
Mstu1 is required for appressorium-mediated infection due to its involvement in the mobilization of lipids and glycogen.[Mstu1] (Mus musculus) PubMed
4807.
CaM targets to the germ tubes, conidia, mycelia and the least in the aerial hypha. [CaM] (Mus musculus) PubMed
4808.
Plays an important role in the autolytic process in A. nidulans. (chiB; class V chitinase) (Mus musculus) PubMed
4809.
Study shows that ASTA is a physiological sulfate transporter; and reports cloning and characterization of the sulfate permease, sB gene; both genes, sB and astA, are regulated at the transcriptional level by sulfur metabolite repression [sB, astA] (Mus musculus) PubMed
4810.
results expand the number of known and predicted secondary metabolites requiring CfwA/NpgA for their biosynthesis, and suggest that a single PPTase is responsible for the activation of all PKSs and NRPSs in A. nidulans [CfwA/NpgA] (Mus musculus) PubMed
4811.
The Aspergillus nidulans Sur2 homolog BasA is also required for phytosphingosine biosynthesis but is also essential for viability.[BasA protein] (Mus musculus) PubMed
4812.
Results describe the processing of MYC(3)-tagged PacC in Western blots, and show unequivocally that PalB is essential for signaling proteolysis and is definitely not the processing protease [PacC, PalB]. (Mus musculus) PubMed
4813.
effect of substitution of R17 by N17 in PinA has been investigated by computational study, predicted that changing R17 to N17 in PinA lowers the ligand binding affinity as a result of reduced H-bonding between protein & phosphate group of ligand.[PinA] (Mus musculus) PubMed
4814.
The bZIP transcription factor MeaB was found to activate nmrA expression and a conserved element, TTGCACCAT, bound by MeaB in vitro is present in the promoters of NmrA homologues in other filamentous ascomycetes [NmrA and MeaB] (Mus musculus) PubMed
4815.
The results indicate an important role of the pentose phosphate pathway in the fungal proliferation during endogenous DNA damage and polar growth monitored by the AtmA kinase.[AtmA] (Mus musculus) PubMed
4816.
Data show that mitotic cytosolic localization of NapB might facilitate its putative role in the sorting of protein cargoes to the vacuole and that NapB and the mitotic B-type cyclin NimE compete for in vitro binding to KapA. [NapB KapA] (Mus musculus) PubMed
4817.
VosA couples sporogenesis and trehalose biogenesis in Aspergillus nidulans [VosA] (Mus musculus) PubMed
4818.
a gene containing the esd0543 EST, named esdC, was isolated and characterized; the gene structure, the expression pattern during development, and the function of the gene in development were investigated [escD] (Mus musculus) PubMed
4819.
CopA:GFP localized to putative Golgi equivalents that were concentrated at hyphal tips. [CopA] (Mus musculus) PubMed
4820.
Results indicate that pkcA plays an important role in the maintenance of cell integrity (pkcA). (Mus musculus) PubMed
4821.
The identification of two cell end marker proteins, TeaA and TeaR, in Aspergillus nidulans, is described.[TeaA, TeaR] (Mus musculus) PubMed
4822.
Data describe overexpression and characterization of TdiB, which catalyzes the reverse prenylation event during terrequinone A biosynthesis [TdiB] (Mus musculus) PubMed
4823.
The sumO gene was deleted in a diploid and sumODelta haploids were recovered. The mutant was viable but exhibited impaired growth, reduced conidiation and self-sterility.[sumO in strain A234] (Mus musculus) PubMed
4824.
Histone H3 acetylation is not required for transcriptional activation and chromatin remodeling but is required for the repression of prnB and prnD and for the repositioning of nucleosomes in the divergent promoter region.[Histone H3; prnD; prnB] (Mus musculus) PubMed
4825.
Study purified of CoA-transferase from A. nidulans and characterized its biochemical properties; enzyme used succinyl-, propionyl- and acetyl-CoA as CoASH donors and the corresponding acids as acceptor molecules.[CoA transferase] (Mus musculus) PubMed
4826.
In actively growing hyphae, cortical ActA::GFP and FimA::GFP patches were highly mobile throughout the hypha and were concentrated near hyphal apices.[ActA or AN6542.3, FimA or AN5803.3] (Mus musculus) PubMed
4827.
Study isolated the NUDF-associated protein BNFA (for binding to NUDF); BNFA was dispensable for growth and for nuclear migration; GFP-BNFA fusions localized to SPBs at different stages of the cell cycle.[BNFA] (Mus musculus) PubMed
4828.
The eglD gene is constitutively expressed in all developmental stages and compartments of A. nidulans asexual life cycle. [eglD] (Mus musculus) PubMed
4829.
CreA and XlnR form a transcriptional cascade regulating A. nidulans xylanolytic genes.[CreA and XlnR] (Mus musculus) PubMed
4830.
These results suggest that ChiA functions as a GPI-anchored chitinase at the sites where cell wall remodeling and/or cell wall maturation actively take place. [ChiA] (Mus musculus) PubMed
All three MCN proteins likely have cell cycle functions. [MCNA, MCNB, and MCNC] (Mus musculus) PubMed
4833.
Data show that the Aspergillus nidulans kinesin-3 motor protein UncA transports vesicles along a subpopulation of microtubules and is required for fast hyphal extension. (Mus musculus) PubMed
4834.
subcellular localization studies of GFP-fused AmyR in A. nidulans [AmyR] (Mus musculus) PubMed
4835.
Aspergillus nidulans Mlp1 nuclear pore complex protein has previously unrealized mitotic roles involving spatial regulation of spindle assembly checkpoint (SAC) proteins.[Mlp1] (Mus musculus) PubMed
4836.
KapA is required for the completion of both sexual and asexual reproductive cycles. [KapA] (Mus musculus) PubMed
4837.
Deletion mutant strains also accumulated more carbonylated proteins when exposed to hydrogen peroxide indicating that MsrA and MsrB are active players in the protection of the cellular proteins from oxidative stress damage.[MsrA & MsrB] (Mus musculus) PubMed
4838.
SNAD acted as a scaffold protein that is required for the localization of the septation initiation network proteins of SIDB and MOBA to the spindle pole body.[SNAD, MOBA, SIDB] (Mus musculus) PubMed
4839.
Data show that overexpression of nsdC not only enhanced formation of cleistothecia but also overcame inhibitory effects of certain stresses on cleistothecial development, implying that NsdC is a key positive regulator of sexual development: [nsdC] (Mus musculus) PubMed
4840.
PepJ is a deuterolysin-type metallo-proteinase. [PepJ] (Mus musculus) PubMed
4841.
Myosin motor-like domain of CsmB is crucial for its proper localization via interaction with actin. [CsmB] (Mus musculus) PubMed
4842.
Data show that A. nidulans pigP mutants have significantly decreased glycosylphosphatidylinositol synthesis [pigP] (Mus musculus) PubMed
4843.
crucial involvement of the NikA histidine kinase-SskA/SrrA phosphorelay system in both osmotic adaptation and asexual development [NikA histidine kinase] (Mus musculus) PubMed
4844.
The combined evidence points to FlbB as a key factor in the transition to asexual development, playing a role at various control points in which the process could be reversed.[FlbB] (Mus musculus) PubMed
4845.
detailed comparison of the quinol:fumarate reductase enzymes from C. jejuni and H. pylori with that of W. succinogenes [QFR] (Mus musculus) PubMed
4846.
in vitro characterization of PglC as a bacillosamine 1-phosphoryl transferase provides direct evidence for the early steps in the C. jejuni N-linked glycosylation pathway [PglC] (Mus musculus) PubMed
4847.
analysis of PseG of pseudaminic acid biosynthesis [PseG] (Mus musculus) PubMed
4848.
results showed that the point mutation was responsible, via a lack of binding of the CmeR repressor, for increased expression of the CmeABC efflux pump and consecutive multidrug resistance [CmeR] (Mus musculus) PubMed
4849.
In C. jejuni, tet(O) was plasmid-encoded in 54 % of tetracycline-resistant isolates, whereas in C. coli, tet(O) appeared to be located on the chromosome.[tet(O)protein] (Mus musculus) PubMed
4850.
Analyses of transformation frequencies and glycosylation statuses of N-glycosylated proteins indicated partial suppression of pglF by pseC.[ pglF, pseC] (Mus musculus) PubMed
4851.
The crystal structure of CmeR to 2.2 A resolution, revealed a dimeric two-domain molecule with an entirely helical architecture similar to members of the TetR family of transcriptional regulators.[CmerR] (Mus musculus) PubMed
4852.
beta 1,3-galactosyltransferase CgtB variants from the bacterium Campylobacter jejuni have distinct acceptor specificities [CgtB] (Mus musculus) PubMed
4853.
The C. jejuni ppk1 mutant was also defective for the virulence-associated phenotype of intraepithelial cell survival in a tissue culture infection model and exhibited a striking, dose-dependent chick colonization defect [polyphosphate kinase 1] (Mus musculus) PubMed
4854.
Strain 81-176 demonstrated GADH activity, converting d-gluconate to 2-keto-d-gluconate, that was higher at 42 degrees C than at 37 degrees C. In contrast, cj0414 and cj0415 mutants lacked GADH activity.[cj0414 and cj0415 in strain 81-176] (Mus musculus) PubMed
4855.
The results demonstrate that cytolethal distendin toxin CDT(+) C. jejuni strains adhere to and invade epithelial cells more efficiently than CDT(-) strains. CDT is responsible for intestinal pathology and the colon is the major target. [DT] (Mus musculus) PubMed
4856.
Diffraction data have been collected from these crystal forms to 2.5 and 2.95 A resolution, respectively[ stationary-phase survival E] (Mus musculus) PubMed
C. jejuni strains carrying a sialyltransferase gene (cst-II), which is essential for the biosynthesis of ganglioside-like lipooligosaccharides, are associated with the development of Guillain-Barre syndrome (Mus musculus) PubMed
4859.
CetA has two transmembrane helices in a helical hairpin while CetB is a peripheral membrane protein tightly associated with the membrane. [CetA, CetB] (Mus musculus) PubMed
4860.
Key residues in the binding site are essential for Cj0977 virulence function, suggesting a possible function of Cj0977 as an acyl-CoA binding regulatory protein.[Cj0977, sigma 28]] (Mus musculus) PubMed
Report immunogenicity and immunoprotection of recombinant PEB1 in Campylobacter-jejuni-infected mice. (Mus musculus) PubMed
4863.
The data indicate that Cj1279c is a novel adhesin. Because Cj1279c harbors fibronectin type III domains, the authors designated the protein FlpA, for fibronectin-like protein A.[FlpA] (Mus musculus) PubMed
4864.
We have investigated a novel AA-ABC transporter system, encoded by cj0467 to cj0469 which led us to designate these genes (paqP and paqQ) (Mus musculus) PubMed
4865.
Amino acid substitution mutagenesis demonstrated that R327, a basic amino acid that is highly conserved in CfrA, plays a critical role in ferric enterobactin acquisition in Campylobacter jejuni.[CfrA] (Mus musculus) PubMed
4866.
The crystal structure of the GT family 42 Campylobacter jejuni alpha-2,3/2,8-sialyltransferase (CstII) provides key insights into the sialyl-transfer mechanism, including tentative identification of His188 as the catalytic base [CstII] (Mus musculus) PubMed
4867.
Data conclude that FlpA mediates C. jejuni attachment to host epithelial cells via fibronectin binding. (Mus musculus) PubMed
4868.
the lack of PspC significantly enhances the susceptibility of S. pneumoniae to both bactericidal activity and secretory response by the microglial cells.[PspC] (Mus musculus) PubMed
4869.
data suggest that potD is involved in pneumococcal polyamine transport and is important for pathogenesis within various infection models [potD] (Mus musculus) PubMed
4870.
adr as the structural gene of the pneumococcal peptidoglycan O-acetylase was identified. (adr) (Mus musculus) PubMed
4871.
Surface expression of PspC was analysed in pneumococcal isolates of different pathological sources. [PspC] (Mus musculus) PubMed
4872.
structure-function studies of previously uncharacterized glycogen-binding modules in the surface-anchored pullulanase SpuA; multivalent binding to glycogen leads to a strong interaction with alveolar type II cells in mouse lung tissue [SpuA] (Mus musculus) PubMed
4873.
Ply, PspA, and PspC expression resulted in C3 degradation in vitro and in vivo.[Ply, PspA, PspC] (Mus musculus) PubMed
4874.
of 174 S. pneumoniae isolates, 76 (44%) had alterations in all of the three genes examined (pbp1a, pbp2b, and pbp2x), 81 (47%) had alterations in one or two of the genes, and 17 (10%) had no alterations [pbp1a, pbp2b, pbp2x] (Mus musculus) PubMed
4875.
In tetracycline-susceptible pneumococci with erm(B)-mediated erythromycin resistance, the erm(B) gene is carried on a variety of Tn916-related genetic elements either lacking tet(M) or, more often, carrying an unexpressed tet(M) gene. [ErmB] (Mus musculus) PubMed
4876.
While various adherence mechanisms have been characterized for pneumococci, the specific interaction of PspC with complement factor H represents a novel mechanism that tethers pneumococci to host tissues.[PspC protein] (Mus musculus) PubMed
4877.
characteristics of four optochin-resistant (Opt(r)) Streptococcus pneumoniae isolates from Brazil; all four Opt(r) isolates presented mutations in the nucleotide sequence coding for the c subunit of F(0)F(1) ATPase [atpC] (Mus musculus) PubMed
4878.
We conclude that a suicide gene of pneumococcus is spxB, which induces an apoptosis-like death in pneumococci and confers a selective advantage in nasopharyngeal cocolonization. [SpxB] (Mus musculus) PubMed
4879.
Upstream of czcD a gene was identified, encoding a novel TetR family regulator, SczA, that is responsible for the metal ion-dependent activation of czcD expression.[SczA, czcD] (Mus musculus) PubMed
4880.
CpsA expression under ambient oxygen concentrations correlates with serotype-specific invasiveness and is inversely associated with the prevalence of serotype-specific carriage.[cpsA] (Mus musculus) PubMed
4881.
rRNA structures that are required for efficient methylation by RlmA(II) [RlmA] (Mus musculus) PubMed
4882.
examined susceptibility to erythromycin and distribution of macrolide-resistance genes, mefA and ermB in S. pneumoniae isolates from upper respiratory tracts of children in 4 cities in the Sapporo district, Hokkaido prefecture, Japan [mefA and ermB] (Mus musculus) PubMed
4883.
The effects of multiple antibiotics on pneumolysin synthesis in Streptococcus pneumoniae were compared.[pneumolysin] (Mus musculus) PubMed
4884.
Data suggest that RrgA is central in pilus-mediated adherence and disease, even in the absence of polymeric pilus production [RrgA] (Mus musculus) PubMed
4885.
pneumolysin may be a particularly potent pneumococcal virulence factor in the setting of cirrhosis.[Pneumolysin from ATCC6303 strain] (Mus musculus) PubMed
4886.
Telithromycin resistance is shown to be conferred by a deletion in erm(B) gene that increases rRNA methylation. [erm(B)] (Mus musculus) PubMed
4887.
These data strongly suggest that Sp0928 encodes the S. pneumoniae type II signal peptidase (Lsp).[Sp0928 in strain 0100993] (Mus musculus) PubMed
4888.
Variable penicillin resistance determinants were found in PBP 2x, PBP 2b, and PBP 1a in isolates of two Streptococcus pneumoniae clonal groups, Poland 23F-16 and Poland 6B-20. [PBP2x, PBP 2b, PBP1a] (Mus musculus) PubMed
4889.
study analyzed in vitro and in vivo properties of penicillin-binding protein 2x (PBP2x )variants from cefotaxime-resistant laboratory mutants and a clinical isolate[PBP2x] (Mus musculus) PubMed
4890.
In erm(B)-positive tetracycline-resistant pneumococci, Tn6003 was the least common erm(B)-carrying Tn916-related element and Tn6002 the most common. [ermB] (Mus musculus) PubMed
4891.
Results describe the structure, ligand recognition and mechanism of sulfonamide resistance of dihydropteroate synthase (DHPS) from Streptococcus pneumoniae [DHPS]. (Mus musculus) PubMed
4892.
A young mouse model is established for complicated pneumococcal pneumonia. This model proved that allelic variation of zmpB affects the virulence of S. pneumoniae.[zmpB] (Mus musculus) PubMed
4893.
We demonstrated that 2 genetic loci, SP_2170 (AdcB, zinc ABC transporter) and SP_0157 (hypothetical protein), were involved in adherence to A549 cells.[SP_2170 and SP_0157 in strain 820047] (Mus musculus) PubMed
4894.
It was determined that the pilus locus is down-regulated by preexisting networks designed for adhesion and cation transport/response and that its regulation occurs through RlrA. [RlrA] (Mus musculus) PubMed
4895.
Transcription of dnaK and groEL operons in Streptococcus pneumoniae in regulated by HrcA and calcium. (Mus musculus) PubMed
4896.
Sequence analysis revealed that most penicillin-nonsusceptible S. pneumoniae isolates (penicillin MIC > or = 1.5 microg/mL and cefotaxime MIC > or = 2 microg/mL) shared identical PBP2b, PBP2x, and PBP1a amino acid profiles.[PBP2b, PBP2x, PBP1a] (Mus musculus) PubMed
4897.
The structure of a neuraminidase from S. pneumoniae: the crystal structure of NanB in complex with its reaction product 2,7-anhydro-Neu5Ac is reported. (Mus musculus) PubMed
4898.
Expression of psaA, pspC and cbpG is differentially regulated. [psaA, pspC and cbpG] (Mus musculus) PubMed
4899.
The purpose of this work was to characterize guanylate kinases from both gram positive and gram negative pathogenic bacteria. (Mus musculus) PubMed
4900.
PfbA is a novel plasmin- and fibronectin-binding protein of Streptococcus pneumoniae and an important factor in the development of pneumococcal infections (Mus musculus) PubMed
4901.
The 2 component regulatory system CiaRH is involved in regulation of pneumocin via upregulation of HtrA, a serine protease, production. [CiaR, CiaH, HtrA] (Mus musculus) PubMed
4902.
analysis of structure and mechanism of Streptococcus pneumoniae endohexosaminidase D [Endo-D] (Mus musculus) PubMed
4903.
the authors show that degradation of model SsrA-tagged proteins in Streptococcus pneumoniae depends primarily or exclusively on ClpXP in vivo.[ClpXP] (Mus musculus) PubMed
4904.
certain S. pneumoniae strains transport and potentially metabolize the histo-blood group antigen carbohydrates of its host (Mus musculus) PubMed
4905.
PspA-capsular polysaccharides conjugate vaccine produced strong protection to mice against the invasion of 1, 5, 6B, 19F, 23F serotypes. (Mus musculus) PubMed
4906.
These data demonstrate a previously unsuspected role for branched-chain amino acid transport during infection for S. pneumoniae. [LivJHMGF] (Mus musculus) PubMed
4907.
identified a new allelic variant of PspC (PspC4.4) as a major ligand for complement inhibitor C4b-binding protein [PspC] (Mus musculus) PubMed
Here, we show that LytR, a pneumococcal protein from the LytR-CpsA-Psr family, is essential for normal septum formation in cell division. [LytR] (Mus musculus) PubMed
4910.
These findings demonstrate that S. pneumoniae phages use the ubiquitous host autolysin, LytA, to accomplish an optimal phage exiting strategy.[LytA] (Mus musculus) PubMed
4911.
Taken together, these data suggest that EstA of Streptococcus pneumoniae is a novel inducer of NO and pro-inflammatory cytokines by activating the NF-kappaB, p38 and ERK 1/2 MAPK pathways during inflammatory responses.[EstA] (Mus musculus) PubMed
4912.
Results present the structure of Wzb in complex with phosphate and high-resolution structures of apo-CpsB and a phosphate-complexed CpsB [CpsB] (Mus musculus) PubMed
4913.
SpxA1 is a negative transcriptional regulator of X-state development. [Spx1] (Mus musculus) PubMed
4914.
role of the interaction of DivIB with FtsL and DivIC proteins [DivIB,FtsL,DivIC] (Mus musculus) PubMed
4915.
clpE gene-deficient Streptococcus pneumoniae expresses fewer kinds of proteins at also lower levels than the wt bacteria, suggesting that ClpE allows the bacteria to adapt to different host environments by inducing the expression of special proteins[clpE] (Mus musculus) PubMed
4916.
Solving two crystal structures for SrtC suggests that an opening of a flexible lid and a concomitant cysteine rotation are important for catalysis and the activation of the catalytic cysteine of pilus-associated sortases.[Sortase C] (Mus musculus) PubMed
4917.
Genetic dependencies of patch formation suggest that patch formation involves cross talk between Myo1p and Wsp1p/Vrp1p pathways.[Myo1, vrp1, wsp1] (Mus musculus) PubMed
4918.
analysis uncovers an important role for Grn1p/GNL3L within this unique group of nucleolar GTPases (Mus musculus) PubMed
4919.
Moc3 (SPAC821.07c) was a novel protein containing a Zn-finger (Zn(2)-Cys(6)) motif. Thus, Moc3 is not only involved in sexual development, but also in ascus formation and DNA integrity in an independent manner with Moc1 and Moc2 in S. pombe. (Mus musculus) PubMed
4920.
characterizeation of Pmo25p; it is required to maintain polarized growth in interphase and is involved in cell separation following cytokinesis it's an essential protein required for polar growth [Pmo25p] (Mus musculus) PubMed
4921.
Dcp1p binding to Dcp2p may regulate Dcp2p activity through conformational changes of the two domains [Dcp2p] (Mus musculus) PubMed
4922.
Genetic epistasis studies and whole genome expression profiling show that Cip1 and Cip2 exert posttranscriptional control of gene expression in a manner that is counteracted by Csx1. [cip1, cip2, csx1] (Mus musculus) PubMed
4923.
Mok12p, Mok13p, Mok14p are required for sporulation to succeed [Mok12p, Mok13p, Mok14p] (Mus musculus) PubMed
4924.
a novel DNA repair heterodimer of Nse5 and Nse6, which are nonessential nuclear proteins critical for chromosome segregation in fission yeast [NSE5, NSE6] (Mus musculus) PubMed
4925.
Mia1p is a microtubule-binding protein that preferentially localized to the minus ends of microtubules and is associated with the sites of microtubule attachment to the nuclear envelope. (Mus musculus) PubMed
4926.
Up-regulation of the S. pombe thioredoxin reductase TrxR gene is mediated by Pap1 via the transcriptional motif( s) located on the -499 approximately -186 bp region. [TxR][Pap1] (Mus musculus) PubMed
4927.
Swe1 prevents Clb2-Cdk1-mediated mitotic activities, but has little effects on Clb5-Cdk1-associated S-phase progression. (Swe1) (Mus musculus) PubMed
4928.
RecQ helicase Rqh1 reacts with homologous recombinant proteins in the repair of a double strand break created at a unique site within the Schizosaccharomyces pombe genome. (Mus musculus) PubMed
4929.
a possible contribution of MR1 gene to the lethal process taking place in irradiated cells [MR1 gene] (Mus musculus) PubMed
4930.
A complex including Bqt1 and Bqt2 is essential for connecting telomeres to the SPB (spindle-pole body - the centrosome equivalent in fungi). [bqt1, bqt2] (Mus musculus) PubMed
4931.
These results indicate that the vps26(+), vps29(+) and vps35(+) gene products are required for retrograde transport of SpVps10p from the prevacuolar compartment back to the Golgi in Sch. pombe cells.[vps26+, vps29+, vps35+] (Mus musculus) PubMed
4932.
Num1p functions as a cortical-anchoring factor for dynein. Num1p is expressed in a meiosis-specific manner and localized to the cell cortex through its C-terminal PH domain (Mus musculus) PubMed
4933.
The agn1 promoter contains three copies of the nucleotide sequence motif CCAGCC, whose presence seems to correlate with Ace2p-mediated transcription activation (agn1)(Ace2p). (Mus musculus) PubMed
4934.
Telomere bouquet formation requires Bqt2p as a linking component and is finely regulated during meiotic progression. [Bqt2p] (Mus musculus) PubMed
4935.
These results suggest a fundamental role for Ppc89 in organization of the S. pombe spindle-pole body (SPB). (Mus musculus) PubMed
4936.
The functional mechanism of FMO from Schizosaccharomyces pombe using the crystal structures of the wild type and protein-cofactor and protein-substrate complexes was analyzed. (FMO) (Mus musculus) PubMed
4937.
Eri1 controls the accumulation of heterochromatic siRNAs and negatively regulates the RNAi-mediated heterochromatin assembly. (Mus musculus) PubMed
4938.
The two activities of La in tRNA maturation map to its two conserved RNA-binding surfaces (La protein). (Mus musculus) PubMed
4939.
Map4p is a mating type-specific adhesin required for mating in h(+) cells and enhances cell adhesion when overexpressed. (Mus musculus) PubMed
4940.
A functional analysis of spo5(+)(mug12(+)) of Schizosaccharomyces pombe, which encodes a putative RNA-binding protein, is reported here. (Mus musculus) PubMed
4941.
The calcineurin-dependent response element (CDRE) in the promoter region of prz1(+) gene was identified and the calcineurin activity in living cells was monitored. (Mus musculus) PubMed
4942.
results confirm that TrxR is a crucial determinant of the level of cellular ROS during oxidative stress as well as in the normal state[thioredoxin reductase] (Mus musculus) PubMed
4943.
SWIRM1 and SWIRM2 are S pombe proteins with close homology to human histone H3 lysine 4 demethylase [SWIRM1, SWIRM2] (Mus musculus) PubMed
4944.
These results suggest that Sld3 functions furthest upstream in initiation complex assembly, followed by GINS and Cut5, then Cdc45. Consistent with this conclusion, DDK but not cyclin-dependent kinase (CDK) was required for Sld3 loading.[Sld3, Cdc45, DDK] (Mus musculus) PubMed
4945.
we show conclusively that the novel mitochondrial ADH is encoded by adh4 and, as such, is unrelated to ADH isoenzymes found in mitochondria of other yeasts.[adh4] (Mus musculus) PubMed
4946.
A pof14 mutant lacking the F-box and an skp1-3 temperature sensitive mutant behave as wild type in the presence of oxidant showing that Pof14 function is independent of SCF. (Mus musculus) PubMed
4947.
cyclin-dependent kinase 8 module forms a distinct structural entity that binds to the head and middle region of Mediator, thereby sterically blocking interactions with RNA polymerase II [cyclin-dependent kinase 8] (Mus musculus) PubMed
4948.
These results suggest a close relationship between Cam2 and Myo1. In addition, both F-actin and Myo1 localized with Cam2 in the leading edge region [F-actin and Cam2]. (Mus musculus) PubMed
4949.
The results indicate that the S. pombe pbh1 gene is up-regulated under metabolic oxidative stress in a Pap1-dependent manner. [Pbh1] (Mus musculus) PubMed
4950.
results suggest that XPB/Ptr8p plays roles not only in nucleotide excision repair and transcription,but also plays a conserved role in mRNA export. (Mus musculus) PubMed
4951.
Data suggest that Raf-1 may interfere with the role of Rad24 by competing with Rad24 for binding to Cdc25 or a direct phosphorylation of Cdc25, bypassing the checkpoint pathway in DNA repair through Cdc25 activation [Cdc25, Rad24]. (Mus musculus) PubMed
4952.
DNA-replication stress appears to allow Caf1 to interact with Suc22, resulting in release of the nucleoplasmic Spd1-Suc22 assembly (Caf1 and Suc22). (Mus musculus) PubMed
4953.
results show Sod22 has broad substrate specificity upon expression in S. cerevisiae & contributes to tolerance to high external levels of K(+); the S. pombe genome encodes 2 plasma membrane alkali metal cation/H(+) antiporters with different roles [Sod22] (Mus musculus) PubMed
4954.
These findings demonstrate that PGRMC1 is required for P450 activity and suggest that interindividual variation in PGRMC1 function may impact multiple biochemical pathways and drug metabolism. (Mus musculus) PubMed
4955.
crystal structures at 2.9 and 2.6 A resolution for ATP- and AMP-bound forms of a core alphabetagamma adenylate-binding domain from the fission yeast AMPK [AMPKalpha, beta, gamma] (Mus musculus) PubMed
4956.
mus7(+) is involved in the repair of replication-associated DNA damage in the fission yeast Schizosaccharomyces pombe [mus7(+)] (Mus musculus) PubMed
4957.
A second fission yeast Argonaute complex is identified which contains, in addition to Ago1, Arb1 and Arb2, both of which are required for histone H3 Lys9 (H3-K9) methylation, heterochromatin assembly and siRNA generation.[Arb1, Arb2] (Mus musculus) PubMed
4958.
We propose that Agn2p (endo-(1,3)-alpha glucanase) participates in the endolysis of the ascus wall by hydrolysing its (1,3)-alpha-glucan, thereby assisting in the release of ascospores. [Agnp] (Mus musculus) PubMed
4959.
Results suggest that during Rhp51-dependent repair of DSBs, Rqh1-Top3 suppresses crossovers in the Rhp57-dependent pathway while Mus81-Eme1 and possibly Rqh1 promote crossovers in the Swi5-dependent pathway [Mus81, Eme1]. (Mus musculus) PubMed
4960.
Schizosaccharomyces pombe UGA1 (GABA aminotransferase) transaminates only gamma-aminobutyrate and not beta-alanine: UGA1 (Mus musculus) PubMed
4961.
In addition to nuclear localization, a functional Cys-rich domain or nuclear export signal element in Cuf1 is required to appropriately regulate copper transport gene expression in response to changes in intracellular copper concentration.[Cuf1, Crm1] (Mus musculus) PubMed
4962.
Dominant mutations in the Schizosaccharomyces pombe spindle pole body (SPB) component Cut12 enable cdc25.22 mutants to overcome a G2 arrest. [Cut 12.1 protein] (Mus musculus) PubMed
4963.
Results suggest a crucial role for S. pombe Hop2-Mnd1 in homologous pairing and strand exchange by Dmc1 and Rad51 recombinases (Hop2 and Mnd1). (Mus musculus) PubMed
4964.
a microtubule-associated protein, Alp7, which forms a complex with Alp14, is a target of Ran in yeast for spindle formation [Alp7, Ran] (Mus musculus) PubMed
4965.
The Dds20 protein has functions in the Cds1-independent mechanism of UV damage tolerance of DNA.(Dds20) (Mus musculus) PubMed
4966.
Overexpression of Jmj2 but not a catalytically inactive mutant reduced histone H3-Lysine-4 trimethylation levels in vivo and suppressed the toxicity caused by overexpression of the histone H3 lysine 4-binding protein [jmj2 protein] (Mus musculus) PubMed
4967.
Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe [BHD] (Mus musculus) PubMed
4968.
characterized the sterol signal for Sre1 activation (Sre1); the sterol-sensing domain of Scp1 is important for regulating Sre1 proteolysis (Scp1) (Mus musculus) PubMed
4969.
Neither Fps1 nor Spo9 alone functions as a GGPS, but the two proteins together form a complex with GGPS activity.[Fps1, Spo9, GGPS] (Mus musculus) PubMed
4970.
concerted actions of Spc1 and Lkh1 are required for the activation of Csx1 during oxidative condition in the fission yeast S. pombe[Csx1 and Lkh1] (Mus musculus) PubMed
4971.
Electron microscopy studies were carried out to reveal the quaternary structure of the homo-octameric Pfk1 from S. pombe in the F6P-bound and in the ATP-bound state. (Mus musculus) PubMed
4972.
potential relevance of Bin1-Ku interaction to cancer are discussed in light of these findings[pku80 and hob1] (Mus musculus) PubMed
4973.
These findings suggest that cdc42p and bud6p activate for3p by relieving autoinhibition.[For3, cdc42, Bud6] (Mus musculus) PubMed
4974.
Collectively, the results imply that Rad9 plays a protective role against nitrosative and nutritional stress and is positively regulated by NO and nitrogen starvation in a Pap1-dependent manner. [Rad9, Pap1] (Mus musculus) PubMed
4975.
In this study, proteasome-COP9-initiation factor proteasome subunit, Rpn7, was isolated as a high copy suppressor that rescued the proteasome defects in yin6 null cells. (Mus musculus) PubMed
4976.
Two related Schizosaccharomyces pombe proteins, Rfp1 and Rfp2, each having an N-terminal SUMO-interacting motif (SIM) and a C-terminal RING-finger domain, were identified.[Rpf1, Rpf2] (Mus musculus) PubMed
4977.
propose a model for the regulation of the activity of the Spc1-stress-activated protein kinase signaling pathway by methylglyoxal in Schizosaccharomyces pombe[Spc1] (Mus musculus) PubMed
4978.
Disruption of the sir2 gene in the superoxide dismutase deficient mutant enhanced the short chronological lifespan without more enhanced protein oxidation.(sir2)(sod) (Mus musculus) PubMed
4979.
The tobacco (Nicotiana tabacum) day-neutral cv. Samsun transformed with the S. pombe mitotic activator gene cdc25 was used to study the onset of flowering.[cdc25] (Mus musculus) PubMed
4980.
The conserved biochemical function of translin is not implicated in primary pathways for regulating genome stability and/or segregation.[Translin, TRAX] (Mus musculus) PubMed
4981.
the ability of Pot1 to unfold the antiparallel tetraplex is required for telomerase-mediated telomere regulation. (Mus musculus) PubMed
4982.
The results show that Bot1p has a novel function in the control of cell respiration by acting on the mitochondrial protein synthesis machinery. (Mus musculus) PubMed
4983.
Expression of mag1 in the triple mutant confirmed the contribution of Mag1p and to base excision repair of methanesulfonate resistance. (Mus musculus) PubMed
4984.
Pxl1p might cooperate with type II myosin and Rng2p-IQGAP to regulate actomyosin ring constriction as well as to maintain its integrity during constriction. (Pxl1p) (Mus musculus) PubMed
4985.
The F-box & DNA helicase domains play indispensable but distinct roles in Fbh1 function. SCFFbh1 complex assembly is needed for the nuclear localization & DNA-damage-induced focus formation of Fbh1 & is prerequisite for the Fbh1 recombination function. (Mus musculus) PubMed
4986.
The total GSH level was more significantly enhanced in the KP1 cells overexpressing gamma-GT2 than gamma-GT1 during nitrogen starvation. [gamma GT1,gamma GT2] (Mus musculus) PubMed
4987.
Two sporulation-specific genes, spo13(+) and spo2(+), which are not required for progression of meiotic nuclear divisions, but are essential for sporulation, were analyzed.[Spo2, Spo13] (Mus musculus) PubMed
4988.
Nip1/Ctp1 is a functional counterpart of Sae2/Com1 and CtIP.(Nip1/Ctp1) (Mus musculus) PubMed
4989.
inactivation of the complex leads to loss of thiolation on tRNAs and to a thermosensitive decrease of viability associated with marked ploidy abnormalities and aberrant development(uridine tRNA thiolase Ctu1-Ctu2) (Mus musculus) PubMed
4990.
These results suggest that Hsp90 plays a specific role in the S. pombe glucose/cAMP pathway.[Git10] (Mus musculus) PubMed
4991.
SpHsp16.0 is likely to interact with denatured CS in the dissociated state, while SpHsp15.8 is likely to interact with CS in a large complex. [Hsp15.8] (Mus musculus) PubMed
4992.
Slk1p and Sid2p play a role in forespore membrane assembly by facilitating recruitment of components of the secretory apparatus, such as Psy1p, to allow membrane expansion [Slk1 protein] (Mus musculus) PubMed
4993.
Ers1 is a rapidly diverging protein essential for RNA interference-dependent heterochromatic silencing in Schizosaccharomyces pombe (Mus musculus) PubMed
4994.
Atx1 acts as a copper carrier to deliver copper to Cao1. [Atx1, Cao1] (Mus musculus) PubMed
4995.
We propose that chromatin assembly factor (CAF1) functions in heterochromatin maintenance by recruiting dislocated Swi6 during replication to replicated heterochromatin at the replication fork. [CAF1 (Pcf1,Pcf2,Pcf3)] (Mus musculus) PubMed
4996.
The alpha-amino group of the d-alanyl moiety of the lysino-d-alanyl residue serves as a catalytic base in the same manner as the epsilon-amino group of Lys57 of the original spSR.[Serine racemase] (Mus musculus) PubMed
4997.
Tn the yeast Schizosaccharomyces pombe, tdp1 mutant cells progressively accumulate DNA damage and rapidly lose viability in a physiological G0/quiescent state. (Mus musculus) PubMed
4998.
Functionally distinct isoforms of Cik1 are differentially regulated by APC/C-mediated proteolysis. (Mus musculus) PubMed
4999.
Degradation of Sre1 in the absence of Scp1 requires the ER-associated degradation (ERAD) components Ubc7, an E2 ubiquitin conjugating enzyme, and Hrd1, an E3 ubiquitin ligase.[Ubc7, Hrd1] (Mus musculus) PubMed
5000.
Schizosaccharomyces pombe contains two tRNase Z(L) genes, designated sptrz1(+) and sptrz2(+) and both are essential for growth[sptrz1 and sptrz2] ] (Mus musculus) PubMed
5001.
Dni1p plays a relevant role in co-ordinating membrane organization and cell wall remodelling during mating. [Dni1p] (Mus musculus) PubMed
5002.
the 3.2 A resolution structure of Schizosaccharomyces pombe Xpot in complex with tRNA and RanGTP, and the 3.1 A structure of unbound Xpot, revealing both nuclear and cytosolic snapshots of this transport factor [Xpot] (Mus musculus) PubMed
5003.
Data show that fission yeast kinesin-6 motor klp9p binds to the microtubule antiparallel bundler ase1p at the midzone at anaphase B onset [Klp9p]. (Mus musculus) PubMed
5004.
Describe a model of cullin-RING ubiquitin ligase (CRL) control in which substrate availability toggles CRLs between COP9 signalosome and CAND1(TIP120A) cycles. (Mus musculus) PubMed
5005.
the crystal structures of the C-terminal domain of the Saccharomyces cerevisiae Stn1 and the Schizosaccharomyces pombe Ten1 proteins are reported. (Ten1) (Mus musculus) PubMed
5006.
The abnormal degradation of TRH and GnRH, and perhaps other neuropeptides N-terminally blocked with a pyroglutamyl moiety, by trypanosome PGP, may contribute to some of the endocrine lesions observed in African trypanosomiasis. [PGP] (Mus musculus) PubMed
5007.
Genes for three proteins (PEX6, PEX10, PEX12) involved in glycosome biogenesis of Trypanosoma brucei were identified [PEX6, PEX10, PEX12] (Mus musculus) PubMed
5008.
AUK1 plays an essential role in cytokinesis that cannot be affected by changes in the level of polo-like kinase; TbAUK1 is also the first identified protein that couples both mitosis and kinetoplast replication with cytokinesis in the trypanosome [AUK1] (Mus musculus) PubMed
5009.
data indicate that trypanosomes utilize TRACK a RACK1 homologue to regulate the final stages of mitosis; disrupting the interaction between TRACK and its partners might be targeted in the design of novel therapies [TRACK] (Mus musculus) PubMed
5010.
Results report the first functional characterisation of a Trypanosoma brucei basal body-cytoskeletal NIMA-related kinase (NRK) protein, TbNRKC [NRKC]. (Mus musculus) PubMed
5011.
Data suggest that dDual targeting of a single tRNA(Trp) requires two different tryptophanyl-tRNA synthetases in Trypanosoma brucei. [tryptophanyl-tRNA synthetase] (Mus musculus) PubMed
5012.
TbEIF4AI may be involved in protein synthesis while the properties and sequence of TbEIF4AIII indicate that it may be the orthologue of eIF4AIII, a component of the exon junction complex in mammalian cells (TbEIF4AI, TbEIF4AIII). (Mus musculus) PubMed
5013.
IscS and IscU down-regulate the active mitochondrion of procyclic Trypanosoma brucei [Tbiscs, Tbiscu] (Mus musculus) PubMed
5014.
The characterization of MCP6, a novel T. brucei MCF protein, is localized in the mitochondria. (Mus musculus) PubMed
5015.
DOT1A and DOT1B influence the trypanosome cell cycle by regulating the degree of H3K76 methylation.[DOT1A, DOT1B] (Mus musculus) PubMed
5016.
Data show that mitochondrial RNA binding proteins MRP1/MRP2 act as RNA matchmakers by stabilizing the RNA molecule in an unfolded conformation suitable for RNA-RNA hybridization [MRP1, MRP2]. (Mus musculus) PubMed
5017.
findings show that TbAT1 and TbMRPA contribute independently to drug resistance, and the effects from combination of the two mutations were strictly additive [AT1; MRPA] (Mus musculus) PubMed
5018.
Study reports purification a transcriptionally active enzyme through affinity chromatography of its essential subunit, RPB4, the enzyme preparation is active in both promoter-independent and promoter-dependent in vitro transcription assays. [RPB4 protein] (Mus musculus) PubMed
5019.
Catalytic properties of recombinant TbPTR1 and inhibition by the archetypal antifolate methotrexate have been characterized and the crystal structure of the ternary complex with cofactor NADP+ and the inhibitor determined at 2.2 A resolution.(TbPTR1) (Mus musculus) PubMed
5020.
The heteroheptameric Sm core structure varies between spliceosomal snRNPs, and that modulation of the Sm core composition mediates the recognition of small nuclear RNA-specific Sm sites.[U2 SnRNP] (Mus musculus) PubMed
5021.
iPGAM is required for cell growth in procyclic T. brucei [iPGAM] (Mus musculus) PubMed
5022.
T.brucei cap 2'-O methyltransferase (TbCom1) binds specifically to m7GpppN-terminated RNA and catalyzes the transfer of a methyl group from AdoMet to the 2nd transcribed nucleoside to form m7GpppNpNm (T.brucei cap 2'-O methyltransferase). (Mus musculus) PubMed
5023.
the biological significance of tryparedoxin for hydroperoxide detoxification and its function in the parasite defence against oxidative stress (tryparedoxin). (Mus musculus) PubMed
5024.
TbZFP3 is a novel regulator of developmental events in kinetoplastids that acts at the level of the post-transcriptional control of gene expression [TbZFP3] (Mus musculus) PubMed
5025.
the identification and functional characterization of a T. brucei Dicer-like enzyme [Dcl1] (Mus musculus) PubMed
5026.
Data show that UDP-glucose 4'-epimerase is essential for the production of UDP-galactose required for galactosylation of glycoproteins, which is essential for the survival of bloodstream form T. brucei [UDP-glucose 4'-epimerase]. (Mus musculus) PubMed
5027.
Studies of the enzymatic activity of the T. brucei CK2s show that both the affinity for GTP and stimulation by polyamines have been lost and only the features of heparin inhibition and stimulation by polybasic peptides are conserved[CK2] (Mus musculus) PubMed
5028.
RRP6 can be present independent of exosome association[RRP6] (Mus musculus) PubMed
5029.
The essential Golgi-localizing T. brucei ARF1 has a primary role in the maintenance of both post-Golgi transport and endocytosis. (Mus musculus) PubMed
5030.
the identification, structural and biochemical analyses of a novel trypanosomal TUTase, TbTUT4, which represents a minimal catalytically active RNA uridylyltransferase, is reported.[Tut4] (Mus musculus) PubMed
5031.
In addition to the analysis of the crystal structure, 3D nuclear magnetic resonance interaction studies and docking experiments of 6-phosphogluconolactonase are reported here.[6-phosphogluconolactonase] (Mus musculus) PubMed
5032.
Study shows that in the mammalian-infective bloodstream-stage of the African trypanosome, Trypanosoma brucei, SIR2rp1 localizes to the nucleus while SIR2rp2 and SIR2rp3 are both mitochondrial proteins. [SIR2rp1, SIR2rp2, SIR2rp3 proteins] (Mus musculus) PubMed
5033.
a laboratory line of Trypanosoma brucei that adapted to high levels of resistance for the melaminophenyl arsenical drug melarsamine hydrochloride (Cymelarsan), had similarly lost TbAT1 and HAPT1 activity while retaining LAPT1 activity (HAPT1) (Mus musculus) PubMed
5034.
KREPB4 is important for the structural integrity of approximately 20S editosomes, editing endonuclease activity, and the viability of T. brucei cells.[KREPB4] (Mus musculus) PubMed
5035.
cyclin E1 forms complexes with CRK1 in promoting G1/S phase transition; with CRK2 in controlling the posterior morphogenesis during G1/S transition; with CRK3 in promoting passage across the G2/M checkpoint in the trypanosome.(cyclin E1) (Mus musculus) PubMed
5036.
a novel member of the ISWI family of SWI2/SNF2-related chromatin-remodelling proteins (TbISWI) is involved in ES downregulation in Trypanosoma brucei.(ISWI) (Mus musculus) PubMed
5037.
The catalytic mechanism of the Tpx peroxidase resembles that of atypical 2-Cys-peroxiredoxins but is distinct from that of the selenoenzymes [glutathione peroxidase-type tryparedoxin peroxidase] (Mus musculus) PubMed
5038.
These data identify a distinct mechanism for regulating AdoMetDC in the parasite that suggests new strategies for the development of parasite-specific inhibitors of the polyamine biosynthetic pathway.[AdoMetDC] (Mus musculus) PubMed
5039.
A new and unique role for centrin in the segregation of organelles without affecting their multiplication in the procyclic form of T. brucei, is revealed.[Centrin1] (Mus musculus) PubMed
5040.
Crystal structures of Mevalonate diphosphate decarboxylase (MDD) from T. brucei (TbMDD, at 1.8 A resolution) and S. aureus (SaMDD, each diffracting to 2.3 A resolution) have been determined[mevalonate diphosphate decarboxylase ] (Mus musculus) PubMed
5041.
TbPRMT5 is likely to be involved in novel methylation-regulated functions in trypanosomes, some of which may include RNA processing and/or translation.(TbPRMT5) (Mus musculus) PubMed
5042.
Results describe the first eukaryotic cap 1 2'-O-ribose methyltransferase, TbMTr1, a member of a conserved family of viral and eukaryotic enzymes [TbMTr1]. (Mus musculus) PubMed
5043.
Trimethylguanosine synthase (Tgs1)is responsible for hypermethylation of the m(7)G cap of both snRNAs and snoRNAs. [Tgs1] (Mus musculus) PubMed
5044.
These results suggest that Trypanosoma brucei peptide deformylase (TbPDF2) is functionally linked to TbPDF1, and that it can influence the efficiency of oxidative phosphorylation [PDF2, PDF1]. (Mus musculus) PubMed
5045.
Data suggest that Trypanosoma brucei Polo-like kinase is essential for basal body duplication, kDNA segregation and cytokinesis. (Mus musculus) PubMed
5046.
The ADP ribosylation factor 1 (TbARF1) protein remains essential for the viability of these procyclic cells but the major effect of TbARF1-depletion is enlargement of the lysosome.[ARF1] (Mus musculus) PubMed
5047.
JBP2 stimulates de novo J synthesis in newly generated telomeric arrays in blood stream form Trypanosoma. (Mus musculus) PubMed
5048.
The loss of the trypanosomatid-specific proteins p34 and p37 correlates with a diminution in 5S rRNA levels as well as a decrease in ribosome activity and an alteration in ribosome biogenesis.[p34,p37] (Mus musculus) PubMed
5049.
Slow growth and chromosome segregation defect phenotypes are completely reversed upon inducible expression of AGO1, demonstrating the role of AGO1 in chromosome segregation and RNA silencing.[AGO1] (Mus musculus) PubMed
5050.
TbeIF2K2 is a transmembrane glycoprotein expressed both in procyclic and in bloodstream forms.[eIF2 alpha kinase] (Mus musculus) PubMed
5051.
TbUBP1 and TbUBP2 may be relatively nonspecific RNA-binding proteins and that specific effects of overexpression or depletion could depend on competition between various different proteins for RNA binding.[UBP1, UBP2] (Mus musculus) PubMed
5052.
These results suggest that CFB2 is required for bloodstream-form trypanosome cytokinesis.[CFB2] (Mus musculus) PubMed
5053.
p34 and p37 regulate NOPP44/46 cellular localization by facilitating their association with exportin 1 [p34, p37] (Mus musculus) PubMed
5054.
Results describe two Tousled-like kinase homologs, TLK1 and TLK2, in Trypanosoma brucei, but only TLK1 plays an essential role in cell growth. [TLK1 and TLK2] (Mus musculus) PubMed
5055.
Depletion of the Trypanosoma brucei MTR4-like protein TbMTR4 caused growth arrest and defects in 5.8S rRNA processing similar to those seen after depletion of the exosome.[MTR4] (Mus musculus) PubMed
5056.
These data suggest that ICP (cysteine peptidase inhibitor) has a role in controlling the differentiation process and virulence through the modulation of Csyteine peptidase activity. [ICP} (Mus musculus) PubMed
5057.
biochemical evidence is provided that TbCgm1 is a capping enzyme.[TbCGM1] (Mus musculus) PubMed
5058.
Protein sorting by hydrodynamic forces helps to protect trypanosomes against complement-mediated immune destruction in culture and possibly in infected mammals. [VSG] (Mus musculus) PubMed
5059.
These results indicate that the overall structure of the C-terminal tail influences the HK activity of TbHK1.(TbHK1) (Mus musculus) PubMed
5060.
Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing (Metacaspase 2). (Mus musculus) PubMed
5061.
TbUBP and TbUBP2 may accentuate developmental regulation of the Tb927.3.4070-927.3.4110 mRNAs stability.[UBP1, UBP2] (Mus musculus) PubMed
5062.
Dual roles for the exoribonuclease, DSS-1, in degradation of 12S rRNA maturation by-products and as part of a mitochondrial RNA surveillance pathway that eliminates stalled 12S processing intermediates (DSS-1). (Mus musculus) PubMed
5063.
The Gup1p from T. brucei (tbGup1p) strongly prefers C14:0 and C12:0 over C16:0 and C18:0, whereas yeast Gup1p strongly prefers C16:0 and C18:0.[Gup1] (Mus musculus) PubMed
5064.
First reported molecular component of the tripartite attachment complex, connnecting kinetoplast DNA to the flagellar basal body. (p166) (Mus musculus) PubMed
5065.
KREPA6 is essential for the structural integrity and presence of 20S editosomes and for cell viability.(KREPA6) (Mus musculus) PubMed
5066.
findings show that histone acetyltransferase 3 (HAT3) is responsible for H4K4 acetylation [HAT3] (Mus musculus) PubMed
5067.
Together, these results suggest that protein phosphatase 5(PP5) positively regulates the function of Hsp90 to maintain cellular homeostasis during proteotoxic stresses in T. brucei. [PP5, Hsp90] (Mus musculus) PubMed
5068.
TbHTD2 can rescue the respiratory deficient phenotype of the yeast knock-out strain and restore the lipoic acid content, is localized in the mitochondrion and exhibits hydratase 2 activity.[TbHTD2] (Mus musculus) PubMed
5069.
Deletion of the TbALG3(alpha-mannosyltransferase)gene involved in site-specific N-glycosylation and N-glycan processing (Mus musculus) PubMed
5070.
TbTim17 is the translocator of nuclear encoded mitochondrial proteins and its expression is regulated according to mitochondrial activities in T. brucei. [Tim17] (Mus musculus) PubMed
5071.
A trypanosomal golgin, TbG63, is identified and characterized showing that it has a C-terminal membrane anchor and an N-terminus that projects into the cytoplasm.[TbG63] (Mus musculus) PubMed
5072.
These results indicate p67 plays an essential role in maintenance of normal lysosomal structure and physiology in bloodstream-stage African trypanosomes. (LAMP-like protein p67) (Mus musculus) PubMed
5073.
These data suggest that the mechanism by which RBP16 facilitates RNA editing involves its capacity to modulate RNA secondary structure and promote gRNA/pre-mRNA annealing. (Mus musculus) PubMed
5074.
TbMP42 is required for both endonucleolytic cleavage steps of RNA editing, but not for any of the subsequent steps of the editing cycles. (TbMP42) (Mus musculus) PubMed
5075.
Depletion of trypanosome CAF1 delayed deadenylation and degradation of constitutively expressed mRNAs (CAF1). (Mus musculus) PubMed
5076.
Data show that duplication of the bilobed structure required for Golgi duplication is dependent on the single polo-like kinase (PLK) homologue in T. brucei (TbPLK) [Polo-like kinase]. (Mus musculus) PubMed
5077.
A mitochondrial poly(A) polymerase, termed KPAP1, was identified and characterized.(KRAP1) (Mus musculus) PubMed
5078.
ethanolamine-phosphoglycerol is also present in eukaryotic elongation factor 1A of the protozoan parasite Trypanosoma brucei, indicating that this unique protein modification is of ancient origin[eukaryotic elongation factor 1A] (Mus musculus) PubMed
5079.
Initiation of cytokinesis is independent of sister chromatid cohesion or cohesin release following SCC1 cleavage. [SSC1] (Mus musculus) PubMed
5080.
TbRGG2 is an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages [TbRGG2] (Mus musculus) PubMed
5081.
Five crystal structures of the PTS1 binding domain of TbPEX5 were determined, each in complex with a hepta- or decapeptide corresponding to a natural or nonnatural PTS1 sequence.[PTS1 AND PEX5] (Mus musculus) PubMed
5082.
The data suggests a Zn(2+)-dependent metal ion catalysis mechanism for the ribonucleolytic activity of TbMP42 (TbMP42). (Mus musculus) PubMed
5083.
Data show that alternative editing of the mitochondrial cytochrome c oxidase III mRNA in Trypanosoma brucei produces a novel DNA binding protein, alternatively edited protein 1 (AEP-1) [AEP-1]. (Mus musculus) PubMed
5084.
Results obtained indicate that TbDRBD3 binds to a subset of developmentally regulated mRNAs encoding membrane proteins, and that this association promotes the stabilization of the target transcripts (TbDRBD3). (Mus musculus) PubMed
5085.
PLK was found to appear in late S phase and persist in G2/M phase but vanish in G1 phase. [PLK] (Mus musculus) PubMed
5086.
TbTFIIS1 and TbTFIIS2-1,two trypanosome homologues of transcription elongation factor TFIIS, are required for normal cell growth. [TbTFIIS1 and TbTFIIS2-1] (Mus musculus) PubMed
5087.
RNAi silencing of TbSLS1-4 in bloodstream trypanosomes led to rapid growth arrest and eventual cell death.[TbSLS1, 2, 3 & 4] (Mus musculus) PubMed
5088.
P34 and P37 are involved in the ribosomal biogenesis pathway. [P34, P37] (Mus musculus) PubMed
5089.
Results suggest that Trypanosoma brucei Centrin4 is involved in processes that coordinate karyokinesis and cytokinesis [Centrin4]. (Mus musculus) PubMed
5090.
Loss of MIX had a major effect on cytochrome c oxidase activity, the mitochondrial membrane potential, and the production of mitochondrial ATP. [MIX] (Mus musculus) PubMed
5091.
regulation of endocytosis is a physiological function of glycosylphosphatidylinositol-specific phospholipase C in bloodstream T. brucei. (Mus musculus) PubMed
5092.
TbRACK1 is a functional component of the trypanosome ribosome which associates with eukaryotic elongation factor 1A Inactivation of TbRACK1 showed that cytokinesis is selectively inhibited when translation is disrupted. [RACK1] (Mus musculus) PubMed
5093.
The kinetoplastid Trypanosoma brucei Selenophosphate synthetase genes were cloned and the protein overexpressed and purified to apparent homogeneity. (Mus musculus) PubMed
5094.
KMP-11 is a flagellar protein playing critical roles in regulating cytokinesis in both forms of the trypanosomes. [Kmp-11] (Mus musculus) PubMed
5095.
Glyoxalase II functions as general trypanothione thioesterase independent of ketoaldehyde detoxification. [Glyoxalase II] (Mus musculus) PubMed
5096.
The 3'-UTRs of MspA, MspB and MspC are responsible for their differential expression. [MspA, MspB, MspC] (Mus musculus) PubMed
5097.
POLID is a third essential DNA Pol required for kDNA replication. [POLID] (Mus musculus) PubMed
5098.
TbNT11.1, has been functionally expressed in null mutants of Leishmania that are deficient in purine nucleoside or nucleobase uptake and identified as a purine nucleobase transporter. And TbNT12.1, reveals that it is an adenine/pentamidine transporter. (Mus musculus) PubMed
5099.
These results provide evidence for TAX-2 function within the axoneme.[Tax-2] (Mus musculus) PubMed
5100.
A new function of the mitochondrial topoisomerase II (TbTOP2mt) was reported. (TbTOP2mt) (Mus musculus) PubMed
5101.
TbGT8 encodes a UDP-GlcNAc: beta-Gal-GPI beta1-3 N-acetylglucosaminyl transferase which may also influence the processing of the poly N-acetyllactosamine-containing asparagine-linked glycans. [TbGT8] (Mus musculus) PubMed
5102.
the five-protein complex CPC-TbTLK1-TbKIN-B plays key roles in regulating chromosome segregation in the early phase of mitosis [Tousled-like kinase TbTLK1] (Mus musculus) PubMed
5103.
The 82kDa TbncPAP1 is essential for viability of procyclic and bloodstream forms of T. brucei. The recombinant 54kDa TbncPAP2 showed a poly(A) polymerase activity as an individual polypeptide[TbncPAP1, TbncPAP2] (Mus musculus) PubMed
5104.
the mitochondrial porin identified in T. brucei is the main metabolite channel in the outer membrane and therefore the functional orthologue of VDAC.[MITOCHONDRIAL PORIN] (Mus musculus) PubMed
5105.
The TbMTr1 complex specializes the SLA1 H/ACA snoRNP for efficient processing of multiple modifications on the spliced leader RNA substrate.[TbMTr1] (Mus musculus) PubMed
5106.
Trypanosoma brucei UDP-glucose:glycoprotein glucosyltransferase is essential for parasite growth and survival at 40 degrees C.[UDP-glucose:glycoprotein glucosyltransferase] (Mus musculus) PubMed
5107.
While the individual JBP1 null and JBP2 null trypanosomes have reduced J levels, the deletion of both JBP1 and JBP2 generates a cell line that completely lacks base J but still contains glucosyl-transferase activity (JBP1 and JBP2). (Mus musculus) PubMed
5108.
study reports that transcription mediated by pol I requires TbRPB7, a dissociable subunit of the pol II complex; TbRPB7 was found to interact with two pol I-specific subunits, TbRPA1 and TbRPB6z [TbRPB7] (Mus musculus) PubMed
5109.
Peroxin 13 is essential for the parasite; depletion by RNA interference results in mislocalization of glycosomal proteins and death of the parasites. (Mus musculus) PubMed
5110.
Both PTB1 and PTB2 were shown to regulate mRNA stability;and are essential for trans-splicing of genes containing C-rich polypyrimidine tracts; PTB1, but not PTB2, also affects cis-splicing. [PTB1, PTB2] (Mus musculus) PubMed
5111.
TOR1 and TOR2 proteins may function as major regulators of cell growth and cytokinesis (TOR1, TOR2). (Mus musculus) PubMed
5112.
Screening of candidate palmitoyl acyltranferases identified a single enzyme, TbPAT7, that is necessary for calflagin palmitoylation and flagellar membrane targeting.[TbPAT7] (Mus musculus) PubMed
5113.
RNAi silencing reveals an essential role for RABL5 in trypanosome flagellum construction.[RABL5] (Mus musculus) PubMed
5114.
The structure of TbUrm1 (ubiquitin-related modifier 1) shares the highly conserved structure among its ubiquitin superfamily, and studies will shed more light on the road exploring evolution of ubiquitin superfamily: [Urm1] (Mus musculus) PubMed
5115.
study identifes the developmental regulator, TbZFP3, a CCCH-class predicted RNA binding protein, as an isoform-specific regulator of Procyclin surface coat expression in trypanosomes [ZFP3] (Mus musculus) PubMed
5116.
TbPRMT7 is a Type III PRMT, and its robust activity and presence in numerous complexes suggest it plays multiple roles during the complex T. brucei life cycle [PRMT7] (Mus musculus) PubMed
5117.
these results indicate that both KREX1 and KREX2 are important for retention of other proteins in editosomes, and suggest that the reduction in cell viability.[KREX1, KREX2] (Mus musculus) PubMed
5118.
The interaction between U2AF35 and U2AF65 was very weak or not detectable. However, as in other eukaryotes, the interaction between U2AF65 and SF1 was strong.[U2AF35,U2AF65 and SF1] (Mus musculus) PubMed
5119.
TbAUK1 aurora kinase is essential for infection in the mammalian host and can be targeted with small-molecule inhibitors. [AUK1] (Mus musculus) PubMed
5120.
Tb-SUMO interacts with human Ubc9 through residues located on the beta-sheet of Tb-SUMO, which is also similar to that of SUMO-1 and Smt3 suggesting the evolutionary conservation of SUMO and sumoylation in eukaryotes.[SUMO] (Mus musculus) PubMed
5121.
Study identifies tbRAP1 as an intrinsic component of the T. brucei telomere complex and a major regulator for silencing variant surface glycoprotein expression sites, [Rap1] (Mus musculus) PubMed
5122.
Three acid phosphatases (ACP) from lysosomal fractions of T. brucei are purified and described. [ACP I, ACP II, ACP III] (Mus musculus) PubMed
5123.
Depletion studies using RNAi showed that there was a modest growth inhibition in procyclic cells but lethality in bloodstream cells, showing that MORN1 is an essential protein in the bloodstream form of the organism.[MORN1] (Mus musculus) PubMed
5124.
These data demonstrate that prozyme mediated activation of S-adenosylmethionine decarboxylase is a common mechanism required to regulate S-adenosylmethionine decarboxylase activity in the trypanosomatids.[prozyme] (Mus musculus) PubMed
5125.
A new member of the FHIT protein family, designated HIT-45, has been identified and sequenced. This enzyme exhibited typical dinucleoside triphosphatase activity (EC 3.6.1.29), having its highest specificity for diadenosine triphosphate (ApppA). (HIT-45) (Mus musculus) PubMed
5126.
U2B associates with U2-40K, and U2-40K contacts the U2-specific Sm core complex.[U2B] (Mus musculus) PubMed
5127.
Gene knockout indicates that ethanolamine-phosphate cytidylyltransferase s essential for growth and survival for the pathogenic stage of the African trypanosome.[ethanolamine-phosphate cytidylyltransferase] (Mus musculus) PubMed
5128.
suggest that both RNA-specific and life cycle stage-specific factors impact MRP1/2 and RBP16 functions[RBP16, MRP1 and MRP2] (Mus musculus) PubMed
5129.
In the absence of glycosylphosphatidylinositol, the procyclin is N-glycosylated, transported to the lysosomal compartment, and secreted into the culture supernatant. [procyclin] (Mus musculus) PubMed
5130.
The 2.3 A resolution structure of the C-terminal domain of tTFIIB, is described.[TFIIB] (Mus musculus) PubMed
5131.
CRK9 could be specifically involved in regulating cytokinetic initiation in the procyclic form of Trypanosoma brucei.[CRK9] (Mus musculus) PubMed
5132.
Trypanosome-suppressive immunomodulating factor (TSIF) knock-down trypanosomes died within 2 days, indicating that TSIF may be essential for parasite biology.[TSIF] (Mus musculus) PubMed
5133.
A putative, highly divergent homolog of Sec61beta was identified in E. cuniculi. NOTE: This gene (BK005765) not annotated yet (acknowledged in paper) and so currently no Gene record for it. Located between ECU09_0940 (860433) and ECU09_0950 (860434). (Mus musculus) PubMed
5134.
Study describes that an endochitinase, CHT1 a chitin synthase, CHS1 and 2 subtilisin-like proteases, SLP1 and SLP2 are induced during meront to sporont development.[CHS1, CHP1, SLP1, SLP2] (Mus musculus) PubMed
5135.
When expressed in S. cerevisiae, EcTom70 inserts with the correct topology into the outer membrane of mitochondria but is unable to complement the growth defects of Tom70-deficient yeast. [Tom70} (Mus musculus) PubMed
5136.
The crystal structure of a ferredoxin-like protein from Thermoanaerobacter tengcongensis (Tflp), is reported. (Mus musculus) PubMed
5137.
VHv1.1 is at least in part responsible for the inhibitory effect of Campoletis sonorensis ichnovirus on host larval growth and development[VHv1.1] (Mus musculus) PubMed
5138.
Detailed expression profiles of let-7 microRNA in the whole life cycle and cultured cell line of silkworm show a clear association with ecdysone pulse and a variety of biological processes. (Mus musculus) PubMed
5139.
Based on a comparison of the normal W-chromosome and 7 translocation and W-deletion strains we present a map of Fem (female determining gene) relative to the 12 W-specific RAPD markers.[Fem] (Mus musculus) PubMed
5140.
Bombyx mori midgut membrane protein P252, which binds to Bacillus thuringiensis Cry1A, is a chlorophyllide-binding protein, and the resulting complex has antimicrobial activity. (Mus musculus) PubMed
5141.
The pp-1 gene contains 17 exons and codes for two pacifastin-related precursors of different length. [PP1] (Mus musculus) PubMed
5142.
In diapause eggs, an abrupt decrease in phosphorylation of GSK-3beta was found with the onset of diapause. [GSK-3beta] (Mus musculus) PubMed
5143.
mgtC is needed for growth of B. cenocepacia in magnesium-depleted medium and for bacterial survival within murine macrophages. (mgtC) (Mus musculus) PubMed
5144.
data demonstrate that HtrA(BCAL2829) is a virulence factor in B. cenocepacia [HtrA] (Mus musculus) PubMed
5145.
Steady-state kinetic analysis of the BCAL0207 gene product demonstrated that it has 4-hydroxyphenylpyruvic acid dioxygenase (HppD) activity.[HppD] (Mus musculus) PubMed
5146.
the conversion from rough wild type to shv in B. cenocepacia correlates with reduced biofilm formation and virulence, and we determined that BCAS0225 is one gene involved in the regulation of these phenotypes [BCAS0225] (Mus musculus) PubMed
5147.
this study is the first demonstration that the RpoN regulon in B. cenocepacia is involved in delaying phagolysosomal fusion, thereby prolonging bacterial intracellular survival within macrophages. [RpoN in strain k56-2] (Mus musculus) PubMed
5148.
Despite strong sequence similarity, the differences between lectin A and PA-IIL in their specificity, binding site and oligomerization mode indicate that the proteins should have different roles in the bacteria. [lectin A] (Mus musculus) PubMed
5149.
B. cenocepacia rpoE is required for bacterial growth under certain stress conditions and for the ability of intracellular bacteria to delay phagolysosomal fusion in macrophages.[RpoE] (Mus musculus) PubMed
5150.
data show that AtsR is involved in the regulation of genes required for virulence in B. cenocepacia K56-2, including genes encoding a T6SS.[AtsR in strain K56-2] (Mus musculus) PubMed
5151.
Results suggest that the enzyme favours the formation of GDP-mannose instead of mannose catabolism, thus channelling precursors to the formation of glycoconjugates.[BceA(J)] (Mus musculus) PubMed
5152.
This study demonstrates that the orphan LuxR homolog CepR2 contributes to the quorum-sensing regulatory network in two distinct strains of B. cenocepacia.[CepR2] (Mus musculus) PubMed
5153.
ZmpA and ZmpB may influence the resistance of B. cenocepacia to host antimicrobial peptides as well as alter the host protease/anti-protease balance in chronic respiratory infections. [Zinc metalloprotease A/Zinc metalloprotease B/B. cenocepacia K56-2] (Mus musculus) PubMed
5154.
VP22 of the CVI988/Rispens vaccine strain has an intercellular-trafficking function which might allow it to serve as a potential alternative delivering protein instead of virulent strains' VP22. [VP22] (Mus musculus) PubMed
5155.
The results suggested that the VP5 of Marine Birnavirus is a novel anti-apoptosis gene, which could regulate the cell apoptosis-off system.[VP5 gene] (Mus musculus) PubMed
5156.
X-ray diffraction data of Thermotoga petrophila endo-1,5-alpha-L-arabinanase were collected to a resolution of 2.86 A using synchrotron radiation.[endo-1,5-alpha-L-arabinanase ] (Mus musculus) PubMed
5157.
Eugenol oxidase is a flavin-adenine dinucleotide (FAD)-containing oxidase found to be most active with eugenol; its substrate reactivity is strikingly different compared with fungal vanillyl alcohol oxidase [eugenol oxidase] (Mus musculus) PubMed
5158.
Cyclic GMP suppresses pseudopod formation in the back of the cell, whereas the soluble guanylyl cyclase (sGC) protein refines pseudopod formation at the leading edge.[Soluble guanyl cyclase] (Mus musculus) PubMed
5159.
These results suggest that P64's function is to condense the large genome of this virus and assist in packaging this genome into its virion.[P64] (Mus musculus) PubMed
5160.
Mutants of DntR in which residues lining the proposed inducer-binding cavity were modified were constructed in order to identify the structural elements involved in inducer binding and to investigate the mechanism of transcriptional regulation by DntR. (Mus musculus) PubMed
5161.
A novel peptidase (BcepAP)in family M61 with specificity for N-terminal acidic residues of peptide substrates was identified. [BcepAp] (Mus musculus) PubMed
5162.
The conformational transition of B. cepacia lipase was dependent on the solvent. (Mus musculus) PubMed
5163.
CAD is essential for itaconic acid production in A. terreus. [Cad] (Mus musculus) PubMed
5164.
The A. terreus NADP-GDH was more stable and showed non-competitive ammonium inhibition with respect to glutamate compared to A. niger NADP-GDH. [NADP-GDH] (Mus musculus) PubMed
5165.
The amounts of ChA and ChC were significantly reduced when exposed to 75 degrees C for 24 h. [ChA, ChC] (Mus musculus) PubMed
5166.
Expression of chi46 is induced by exposure to the cell walls of plant pathogens and living pathogens, suggesting a role in plant disease resistance. [Chi46] (Mus musculus) PubMed
5167.
The cDNA and partial genomic sequence of ADF (actin-depolymerizing factor) were identified and its role in actin binding and host invasion demonstrated. [ADF] (Mus musculus) PubMed
5168.
HSP70 is a structural component of the synaptonemal complex (SC), and may be involved in SC functions such as chromosomal pairing, recombination, or disjunction. [HSP70] (Mus musculus) PubMed
5169.
CYP619C2 and CYP619C3 are involved in the biosynthesis of patulin. [CYP619C2, CYP619C3] (Mus musculus) PubMed
5170.
N-terminal extension of TrxRh1 was necessary to import the protein into the organelles and TrxRh2 had no N-terminal targeting signal but was efficiently targeted to hydrogenosomes. [TrxRh1, TrxRh2] (Mus musculus) PubMed
5171.
T. vaginalis trimethylguanosine synthase exhibits substrate specificity and amino acid requirements typical of an RNA cap-specific, m(7)G-dependent N2 methyltransferase (trimethylguanosine synthase). (Mus musculus) PubMed
5172.
FDP reduces dioxygen to water but is unable to utilize nitric oxide as a substrate. [FDP] (Mus musculus) PubMed
5173.
Myb2 and Myb3 coactivate ap65-1 transcription against Myb1 repression through competitive promoter binding. [ap65-1, Myb1, Myb2 and Myb3] (Mus musculus) PubMed
5174.
Study on the molecular basis for the DNA recognition of Myb1 DNA-binding domain (Myb1). (Mus musculus) PubMed
5175.
A post-transcriptional regulatory mechanism by iron for tvcp4 mediated by IRE/IRP-like interactions was found [cysteine proteinase 4, tvcp4]. (Mus musculus) PubMed
5176.
We propose that induction of collagenase-1 by IL-1alpha in both WF and NF depends on a unique combination of cell type-specific signaling pathways. [COLLAGENASE-1] (Mus musculus) PubMed
5177.
Expression of 11beta-HSD1 may be fundamental in the regulation of CSF secretion and the local generation of cortisol may represent a pathophysiological mechanism underlying cortisol-dependent neuroendocrine diseases.[11beta-hsd1]. (Mus musculus) PubMed
5178.
Study demonstrates the activity and gene expression of large neutral amino acid transporters Lat1 (SLC7A5) and LAT2 (SLC7A8)in the rabbit retina. LAT1 is involved in retinal uptake and intravitreal elimination of L-Phe.[Lat1 (SLC7A5) / LAT2 (SLC7A8)] (Mus musculus) PubMed
5179.
These data provide a mechanism by which constitutively and transiently expressed H1 forms can tightly regulate RyR1 channel activity in response to changing levels of expression and degradation of H1 proteins.[RyR1] (Mus musculus) PubMed
5180.
our studies suggest a novel regulatory mechanism in which phosphorylation of Munc18b operates vesicle docking and fusion in regulated exocytosis [Munc18b] (Mus musculus) PubMed
5181.
characterization the full-length cDNA sequence of the rabbit BK channel beta1 subunit gene, which will set the basis for further investigation in the transcriptional regulation of this gene. (Mus musculus) PubMed
5182.
In mouse and rabbit myocytes overexpressing CaMKIIdelta(C) by means of adenovirus-mediated gene transfer, recovery of fractional shortening and Ca transients was not impaired during late acidosis but even slightly improved.[CaMKIId] (Mus musculus) PubMed
5183.
expression of endogenous rabbit peroxisome proliferator-activating receptor and VEGFR2 were significantly increased in the growth factor-transduced muscles, but these inductions were efficiently prevented by 15-LO-1. (VEGFR2) (Mus musculus) PubMed
5184.
The data show that protein kinase B (Akt) activation promotes mitochondrial respiration and ATP production in toxicant-injured renal proximal tubular cells. [protein kinase B (Akt)] (Mus musculus) PubMed
5185.
The Ser or Thr at position 512 is the most important determinant of functional differences in apparent affinity for substrate and cations, and the cation and substrate binding sites are located in close proximity to one another: NaDC1 (Mus musculus) PubMed
5186.
Novel localization of pIgR to the regulated secretory pathway of lacrimal gland acinar cells and its secretion therefrom may be affected by its novel interaction with Rab3D. (Mus musculus) PubMed
5187.
Renal proximal tubular cell (RPTC)proliferation after plating is mediated by HB-EGF produced through an autocrine/paracrine mechanism and RPTC proliferation following oxidant injury is mediated by Src without involvement of HB-EGF. [HB-EGF] (Mus musculus) PubMed
5188.
analysis of ligand binding in cytochrome P450 1A2 [CYP1A2] (Mus musculus) PubMed
5189.
REP52 is synthesized and secreted in a tissue-specific manner by the mid (region 6) and distal (region 7) corpus epididymidis and associates weakly with the sperm surface overlying the principal piece of the tail [REP52]. (Mus musculus) PubMed
5190.
Chronic upregulation/activation of CaMKIID, and protein kinase D (PKD) in heart failure shifts histone deacetylase 5 (HDAC5) out of the nucleus, derepressing transcription of hypertrophic genes. (Mus musculus) PubMed
5191.
G(q)-dependent signalling by the lysophosphatidic acid receptor LPA(3) in gastric smooth muscle: reciprocal regulation of MYPT1 phosphorylation by Rho kinase and cAMP-independent PKA [LPA3, MYPT1] (Mus musculus) PubMed
5192.
results support an earlier observation that the combination of benzphetamine and cyt b 5 binding produce a synergy leading to unique active site structural changes when both are bound[cytochrome P450 2B4] (Mus musculus) PubMed
5193.
Rabbit L-gulonate 3-dehydrogenase was crystallized using the oil-microbatch method at 295 K [L-gulonate 3-dehydrogenase] (Mus musculus) PubMed
5194.
eIF5B or eIF5B/eIF3 also promote Met-tRNA(iMet) binding to IRES-40S complexes, forming 48S complexes that can assemble elongation-competent ribosomes.[eIF2] (Mus musculus) PubMed
5195.
Cardiotonic action of dopamine is due to dopamine D1 receptor and beta2 adrenergic receptor mediated increases in L-type calcium current. (Mus musculus) PubMed
5196.
binding pocket complementary to the reactive substrate fragment which contains all the active site residues needed to catalyze the reaction of the substrate piece or of the whole substrate [glycerol 3-phosphate dehydrogenase ] (Mus musculus) PubMed
5197.
iPLA(2)gamma is required for the prevention and repair of basal lipid peroxidation [iPLA2gamma] (Mus musculus) PubMed
5198.
Report complex regulation of store-operated Ca2+ entry pathway by protein kinase C(PKC)-epsilon in vascular smooth muscle cells. (Mus musculus) PubMed
5199.
Oxytocin-induced contractions within rat and rabbit ejaculatory tissues are mediated by vasopressin V1A receptors and not oxytocin receptors. (Mus musculus) PubMed
5200.
flow unilaterally attenuates FGF8/gap junction-mediated repression of Nodal on the left side, integrating gap junctional communication and FGF8 into the flow-based mechanism of symmetry breakage in the vertebrate embryo[ Nodal ] (Mus musculus) PubMed
5201.
results suggest that NK2 & NK3 but not NK1 receptors are involved in the excitatory modulation of inspiratory activity [NK1, NK2 AND NK3 RECEPTOR] (Mus musculus) PubMed
5202.
TIMP-3 is downregulated in a distinct subpopulation of atherosclerotic foam cells which have increased matrix metalloproteinase 14 (MT-MMP/MMP-14). (Mus musculus) PubMed
5203.
investigated whether oxidant stress plays a role in Ang II-induced AT1R upregulation and its relationship to the transcription factor activator protein 1 (AP1) in CHF rabbits and in the CATHa neuronal cell line [AP-1, Ang II and Jnk]. (Mus musculus) PubMed
5204.
Findings demonstrate that phosphodiesterase 3B (PDE3B) is present in rabbit erythrocytes and are consistent with the hypothesis that PDE3 activity regulates cAMP levels associated with a signaling pathway activated by iloprost in these cells. (Mus musculus) PubMed
5205.
Inhibition of farnesyl-diphosphate farnesyltransferase (squalene synthase) changed macrophage/lipid-rich coronary plaques of hypercholesterolaemic rabbits into fibrous lesions. (Mus musculus) PubMed
5206.
Study isolated two synaptopodin 2 isoforms from rabbit stomach that corresponded to known types of human synaptopodin 2 and synaptopodin 2 bound to Ca2+-calmodulin.[Synaptopodin 2] (Mus musculus) PubMed
5207.
enhancement of gap junction intercellular communication is activated by ET-1 via modulating the expression of connexin43, and plays an important role in the pathogenesis of cerebral vasospasm. (Mus musculus) PubMed
5208.
FGF5 gene could be the potential major gene affecting wool yield or link with the major gene, and polymorphic loci B and C may be used as molecular markers for im-proving wool yield in angora rabbits (Mus musculus) PubMed
5209.
Alpha-T was found in all semen fractions. Half of the total gamma (+beta)-T was found in germ cells, while 50% of total delta-T was accumulated in seminal plasma [alpha-, gamma (+beta)- and delta-tocopherol]. (Mus musculus) PubMed
5210.
CRPV early protein 2 activates the expression of MMP-9 in-trans through AP-1 and ERK1 and may contribute to cancer development and progression via this mechanism within the animal model[AP-1, ERK1, MMP-9] (Mus musculus) PubMed
5211.
two binding sites may be part of the extracellular (stereospecific) and intracellular (non-stereospecific) sugar interaction sites of SGLT1[Sodium-Glucose Transporter 1 ] (Mus musculus) PubMed
5212.
Novel insights of the gastric gland organization revealed by chief cell specific expression of moesin. (Mus musculus) PubMed
5213.
Role of CuZn superoxide dismutase (SOD1) on carotid body function in heart failure rabbits. (Mus musculus) PubMed
5214.
The ratio of non-synonymous to synonymous substitutions is significantly higher in peptide-binding-site codons than non-PBS codons. The high ratio at PBS codons suggests that the rabbit DQA locus may have been under intense selection. DQA. (Mus musculus) PubMed
5215.
Protein kinase A-mediated phosphorylation of the transporter represents a further mechanism in the regulation of SGLT1-mediated glucose transport in epithelial cells[SGLT1] (Mus musculus) PubMed
5216.
Report down-regulation of connexin 43 after load-induced hypertrophy in vitro. (Mus musculus) PubMed
5217.
both DJ-1 and PINK1, and DJ-1 and alpha-Synuclein were positive at 8 h of reperfusion in the same motor neurons, which eventually die[DJ-1] [PINK1] [alpha-Synuclein] (Mus musculus) PubMed
5218.
Indicate that the rabbit provides a relevant model, easily used in laboratories, to study the role of cardiac beta(3)-adrenoceptors in physiological conditions. (Mus musculus) PubMed
5219.
Angiotensin II inhibits the Na+/K+ pump alpha 1 subunit via protein kinase c epsilon-dependent activation of NADPH oxidase subunits. (Mus musculus) PubMed
5220.
Quercetin inhibited myocardial ischemia-reperfusion-induced NOX2 (NADPH oxidase 2) and iNOS (nitric oxide synthase 2) mRNA and protein expression. (Mus musculus) PubMed
5221.
There were no differences in NCX surface distribution or in the spatial relationship to caveolin 3.[NCX, Vaveolin-3] (Mus musculus) PubMed
5222.
results suggest a mechanism whereby nebulin specifies the minimum thin filament length and sarcomere length regulates and coordinates pointed-end dynamics to maintain the relative overlap of the thin and thick filaments during myofibril assembly [nebulin] (Mus musculus) PubMed
5223.
substantial binding between junctophilin-2 and TRPC3 suggests that junctophilin-2 can be a regulatory protein of TRPC3 and/or TRPC3-mediated Ca(2+) homeostasis in skeletal m[TRPC3] (Mus musculus) PubMed
5224.
hypercholesterolemia increases expression of connexin43 in rabbit aortic valve. results suggest that alterations in gap junctional intercellular communication via connexin43 may play a role in development of aortic valve sclerosis[connexin43] (Mus musculus) PubMed
5225.
fibronectin expression in response to the acute mechanical strain resembling aortic regurgitation is upregulated primarily via JNK[fibronectin] (Mus musculus) PubMed
5226.
SAP97 contributes to isoform specific organization of HCN channels within specific domains in the sinoatrial node of the rabbit.[SAP97] (Mus musculus) PubMed
5227.
These data suggest that CLIC2 can interact with RyR1 and modulate its channel activity.[RyR1] (Mus musculus) PubMed
5228.
function of VEGF-B in the vascular system is to act as a "survival," rather than an "angiogenic" factor and that VEGF-B inhibition may offer new therapeutic opportunities to treat neovascular diseases[VEGF-B] (Mus musculus) PubMed
5229.
Upregulation of RGS4 expression by IL-1beta in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3beta pathway. Links for ERK1/2, p38MAPK and GSK3beta. (Mus musculus) PubMed
5230.
Capase-12 seems to be involved in apoptosis induced by ischemia/reperfusion (caspase 12). (Mus musculus) PubMed
5231.
Gingival fibroblast stimulated the release of TGF-beta1, which in turn inhibited the transcription and synthesis of MMP-7.[MMP-7] (Mus musculus) PubMed
5232.
PTPro interaction with specific antibodies acutely increases albumin permeability in glomerular podocytes [PTPro]. (Mus musculus) PubMed
5233.
RANKL protects osteoclasts from the apoptosis-inducing and anti-resorptive effects of bisphosphonates in vitro by incresing the level of Mcl-1 (Mus musculus) PubMed
5234.
cAMP-dependent regulation of CYP19 gene in rabbit preovulatory granulosa cells and corpus luteum (Mus musculus) PubMed
5235.
Urban particulate matter caused severe oxidative stress in macrophages from diabetes mellitus rabbits and up-regulation of cytokine expression and MMP-9 activity. (Mus musculus) PubMed
5236.
In the myocardium, angiotensin 1-7 through its binding to Mas receptor induces a negative inotropic effect modulated by the endocardial endothelium and nitric oxide and independent of AT(1) or AT(2) receptors activation. (Angiotensin 1-7) (Mus musculus) PubMed
5237.
The aim of this study was to investigate the deleterious effects of shockwaves (SWs) using heat shock protein (HSP) 70 expression on obstructed kidneys with different obstruction periods.[HSP70] (Mus musculus) PubMed
5238.
The crystal structure of the N-terminal 210 residues of RyR1 (RyR(NTD)) at 2.5 A, is reported.[Ryr1] (Mus musculus) PubMed
5239.
[I-BABP] Substitution of the helix-turn-helix capping motif of ileal bile acid binding protein (I-BABP) with a flexible Gly-Gly-Ser-Gly linker results in loss of stabilizing hydrophobic contacts and renders the I-BABP beta-clamshell structure unfolded. (Mus musculus) PubMed
5240.
In this study, a previously cloned beta-glucosidase gene, umbgl3B, was heterologously expressed in Escherichia coli, and the biochemical properties of the purified enzyme were characterized.[umbgl3B] (Mus musculus) PubMed
5241.
The anti-adhesive property by insulin may be mediated by the Akt-mediated and nitric oxide-dependent pathway.[Akt] (Mus musculus) PubMed
5242.
Although macrophages were the main source of myeloperoxidase, not all macrophages secreted myeloperoxidase, which suggests that distinct subpopulations contribute differently to atherogenesis [myeloperoxidase]. (Mus musculus) PubMed
5243.
Data show that both with wild-type glutamate transporter EAAC1 and EAAC1-D455N, not only sodium but also lithium could support radioactive acidic amino acid uptake: [EAAC1] (Mus musculus) PubMed
5244.
Wnt-5A (upregulated by IL-1beta) may be associated with cartilage destruction by promoting the expression of matrix metalloproteinases [IL-1beta]. (Mus musculus) PubMed
5245.
These data strongly suggest that nectin-3 may contribute to the identification of corneal epithelial stem cells. (Mus musculus) PubMed
5246.
CCR2/MCP-1 mediated monocyte recruitment and a low shear environment act synergistically to augment neointimal hyperplasia development.[CCR2] (Mus musculus) PubMed
5247.
postconditioning neuroprotective effects on the spinal cord are mediated by phosphatidylinositol 3-kinase--PI3 KINASE (Mus musculus) PubMed
5248.
Results describe the purification and identification of the first L-rhamnose-1-dehydrogenase gene, RHA1, in the yeast Pichia stipitis [RHA1]. (Mus musculus) PubMed
5249.
purifcation, substrate specificity, and phylogenetic relationship to Azotobacter vinelandii and E Coli bacterial LADH[lactaldehyde dehydrogenase] (Mus musculus) PubMed
5250.
Zinc finger motifs and basic motifs of p12 protein have a role in subcelular localization, binding to nucleic aicds, and hypersensitive response induction upon expression from a PVX vector. [p12] (Mus musculus) PubMed
5251.
Erythromycin C-12 hydroxylase (CYP113A1), the P450 cytochrome active in the final stages of erythromycin biosynthesis, was cloned and expressed in E. coli. [EryK} (Mus musculus) PubMed
5252.
amastigotes and promastigotes both express multiple major surface protease (MSP)isoforms, but these MSPs differ biochemically and localize differently in the two parasite stages.[MSP in strain MHOM/BR/00/1669] (Mus musculus) PubMed
5253.
First report of cloning, sequencing, expression, and substrate specificity of recombinant cysteine proteinase B. [CPB] (Mus musculus) PubMed
5254.
results revealed that the virulent strain produced higher amounts of metallopeptidase (gp63) & cysteine peptidase(cpb)molecules, detected both in the surface and cytoplasm regions, than the avirulent counterpart [gp63,cpb] (Mus musculus) PubMed
5255.
phylogenetic, molecular, and biochemical characteristics of SucB, one of two novel intracellular invertases identified in Aspergillus niger [SucB] (Mus musculus) PubMed
5256.
The beta-xylosidase activities of the A. brasiliensis and A. niger strains had similar temperature and pH optima at 75 degrees C and pH 5 and retained 62% and 99%, respectively, of these activities over 1 h at 60 degrees C [beta-xylosidase] (Mus musculus) PubMed
5257.
A new GH12 (glycosyl hydrolase 12) family XEG, AnXEG12A, was overexpressed, purified and characterized [xyloglucan-specific endo-beta-1,4-glucanase, AnXEG12A] (Mus musculus) PubMed
5258.
Solution of these structures will help shed light on the molecular determinants of improved activity and high enantioselectivity towards a broad range of substrates[monoamine oxidase] (Mus musculus) PubMed
5259.
suggest that glucoamylase functions via transient dimer formation during hydrolysis of insoluble substrates and address the question of the cooperative effect of starch binding and hydrolysis[glucoamylase] (Mus musculus) PubMed
5260.
The molecular weight of the subunit was determined to be 76 kDa and the pI = 4.8. [NAGA] (Mus musculus) PubMed
5261.
An in-depth characterization of the Aspergillus niger glucoamylase (glaA) promoter performance was carried out on defined medium.[glaA] (Mus musculus) PubMed
5262.
amino acids of PGI and PGII that are unique in binding the pectin backbone and that are identified as possibly crucial for specificity [PGI & PGII] (Mus musculus) PubMed
5263.
The finding that A. niger does not thrive on nicotinamide as a sole carbon source suggest that the fungal dimethylmalate lyase functions in a presently unknown metabolic pathway.[dimethylmalate lyase in strain N400] (Mus musculus) PubMed
5264.
During secretion stress, hacA transcription starts from a new start site closer to the ATG and relieves the mRNA from the translational block. [HacA] (Mus musculus) PubMed
5265.
Under the conditions of citric acid production alternative oxidase of Aspergillus niger is regulated at the transcription stage.(aox1) (Mus musculus) PubMed
5266.
substrate specificity of a GH12 xyloglucanase from Aspergillus niger [XEG12A] (Mus musculus) PubMed
5267.
Metabolic pathways that are not directly involved in acetate metabolism are influenced by acuB deletion. [acuB] (Mus musculus) PubMed
5268.
Aglu gene contained 2880 bp and encoded a protein of 960 amino acids. [Aglu] (Mus musculus) PubMed
5269.
The A. terreus NADP-GDH was more stable and showed non-competitive ammonium inhibition with respect to glutamate compared to A. niger NADP-GDH. [NADP-GDH] (Mus musculus) PubMed
5270.
The optimal substrate of lipB is 4-nitrophenyl octanoate and the optimal temperature is 50 degrees C. [LipB] (Mus musculus) PubMed
5271.
het-c has no direct function in heterokaryon incompatibility in A. niger because the necessary allelic variation is absent. [het-c] (Mus musculus) PubMed
5272.
A single amino acid change in L-arabitol dehydrogenase contributes significantly to the substrate specificity difference between LAD and xylitol dehydrogenase. [LadA] (Mus musculus) PubMed
5273.
Disruption of fruR, which is a deoxyribonucleoside repressor (DeoR)-type transcriptional regulator co-transcribed with ptsF, resulted in enhanced induction of the fructose-pts operon, ptsI, and ptsH expression in response to fructose.[FruR] (Mus musculus) PubMed
5274.
These results suggest that SugR represses ptsI and ptsH in the absence of PTS sugar and derepression is the mechanism for the induction of the general components of PTS.[SugR] (Mus musculus) PubMed
5275.
narKGHJI operon is repressed by the ArnR protein under aerobic conditions, whereas the expression of the arnR gene is autoinduced by ArnR. (Mus musculus) PubMed
5276.
DcsT gene is a transporter involved in the utilization of C4 dicarboxylates in C. glutamicum. [dcsT] (Mus musculus) PubMed
5277.
These assays revealed that SugR acts as a negative transcriptional regulator of the gapA gene in the absence of sugar, and repression by SugR is alleviated in the presence of sugar...[SugR] (Mus musculus) PubMed
5278.
IdhA is repressed by SugR in the absence of sugar. [IdhA. SugR] (Mus musculus) PubMed
5279.
B2 upregulates Bax and triggers mitochondria-mediated necrotic cell death independent of cytochrome c release [non-structural protein B2] (Mus musculus) PubMed
5280.
The coding region of the inulinase contained 514 amino acids with a calculated molecular mass of 58.04 kDa. [INU1] (Mus musculus) PubMed
5281.
Deletion analyses indicated that aer-2 actively mediates an aerotaxis response, as assayed in succinate soft agar plates as well as a capillary assay. [aer-2] (Mus musculus) PubMed
5282.
A model derived for the 3-dimensional structure of the molecule indicates that subunits exist in 2 distinct conformations in the tetramer, leading to different relative accessibilities of cysteine and tryptophan residues, as observed in solution.[HlyT] (Mus musculus) PubMed
5283.
The conserved aspartate residue in the transmembrane helix of PomB and its H(+)-dependent homologs might act as a ligand for the coupling cation in the flagellar motor.[PomB] (Mus musculus) PubMed
5284.
all the designated DDD aspartates reside in clusters of amino acids that are conserved among piggyBac family transposase members. All four aspartates are necessary for excision to occur in a cellular environment[piggyBac, accession # J04364] (Mus musculus) PubMed
5285.
These results suggested that the mechanism of the proteolysis by the wild-type norovirus 3C-like protease was different from that of typical chymotrypsin-like serine proteases (Mus musculus) PubMed
5286.
Developed sandwich enzyme immunoassay to accurately quantify neurotoxin A, whatever the neurotoxin form. (Mus musculus) PubMed
5287.
The binding sites for gangliosides and phosphatidylethanolamine were identified in BoNT/C and BoNT/D. [BoNT/C, BoNT/D] (Mus musculus) PubMed
5288.
Seven wild-type and ARTT loop-mutant structures of C3 exoenzyme of Clostridium botulinum free and bound to its true substrate, NAD, were presented. (C3 exoenzyme) (Mus musculus) PubMed
5289.
C3 protein induces a proinflammatory response in microglia resembling the classical proinflammatory phenotype elicited by bacterial lipopolysaccharide. [Clostridium botulinum exoenzyme C3] (Mus musculus) PubMed
5290.
The authors that the long-lived nature of C2I in the host cell cytosol was essential for the nonreversible cytotoxic effect of C2 toxin, resulting in delayed apoptosis of the tested mammalian cells.[C2I] (Mus musculus) PubMed
5291.
A protease was purified from the culture medium of Clostridium botulinum serotype C strain Stockholm. (GenBank Accession No. AB325802) (Mus musculus) PubMed
5292.
the crystal structure of BoNT E holotoxin and show that the domain association is different and unique, although the individual domains are similar to those of BoNTs A and B (Mus musculus) PubMed
5293.
The crystallization and preliminary X-ray diffraction analysis to near-atomic resolution of DHDPS from Clostridium botulinum crystallized in the presence of its substrate pyruvate are presented.[DHDPS] (Mus musculus) PubMed
5294.
BLIP surface is tolerant of substitutions in residues that contact TEM-1 beta-lactamase in the structure of the complex[TEM-1 beta-lactamase] (Mus musculus) PubMed
5295.
5'UTR was responsible for a low reporter gene expression, whereas the intergenic region (IR) between LORIEN and MAT2 genes provided high luc levels[LORIEN and MAT2] (Mus musculus) PubMed
5296.
LiSIR2RP1 is an NAD(+)-dependent deacetylase that also exerts an ADP-ribosyltransferase activity. (Mus musculus) PubMed
5297.
Lack of HSP70-II expression has a pleiotropic effect, influencing cell morphology, replication and virulence. [HSP-70II] (Mus musculus) PubMed
5298.
Under the pressure of a death stimulus, EndoG is released from mitochondrion and translocates to the nucleus. [EndoG] (Mus musculus) PubMed
5299.
causes platelet aggregation in a complement- or fibrinogen-dependent manner. [ClfB] (Mus musculus) PubMed
5300.
strains with N-terminal truncations in SrrA displayed defects in growth and abnormally upregulated virulence factor expression under low-oxygen conditions.[SrrA] (Mus musculus) PubMed
5301.
MazFSa cleaves single-strand RNA preferentially at the 5' side of the first U or 3' side of the second U residue within the consensus sequences VUUV' (where V and V' are A, C, or G and may or may not be identical).[MazF] (Mus musculus) PubMed
5302.
ica operon is required for the expression of the important multifunctional virulence determinants eap and emp [Emp] (Mus musculus) PubMed
5303.
The activation of CD14(+) cells by Eap suggests that it could play a significant role in both septic shock and fever, two of the major pathological features of S. aureus infections.[Eap] (Mus musculus) PubMed
5304.
alpha-haemolysin in an agrA mutant background is required for vesicular escape of S. aureus into the host cell cytosol. (alpha-haemolysin) (Mus musculus) PubMed
5305.
clumping factor A (ClfA) was identified as a specific protein bound by factor I; the shed ClfA fragment increased factor I cleavage of C3b into inactive C3b (Mus musculus) PubMed
5306.
SarZ is a functional homologue of MgrA that senses oxidative stress and coordinates the expression of genes involved in metabolic switching, antibiotic resistance, peroxide stress defence, virulence, and cell wall properties. [SarZ] (Mus musculus) PubMed
5307.
These findings suggest that fudoh in the SCCmec type-II region suppresses colony spreading and exotoxin production, and is involved in S. aureus pathogenesis.[Fudoh] (Mus musculus) PubMed
5308.
MgrA acts as an activator of SarZ,which has an important role in controlling regulatory and virulence gene expression in S. aureus. [MgrA, SarZ] (Mus musculus) PubMed
5309.
Ectopic expression of MazF led to a rapid decrease in growth but cells remained viable.[MazF] (Mus musculus) PubMed
5310.
Thus, IsdA is an important adhesin to human ligands, which predominate in its primary ecological niche.[IsdA] (Mus musculus) PubMed
5311.
CymR controls utilization of sulfur sources of human origin such as taurine and homocysteine and is required for efficient biofilm formation. [CymR] (Mus musculus) PubMed
5312.
study found recognition specificity resides in pepper Bs3 promoter & is determined by binding of AvrBs3 to promoter region; data suggest recognition mechanism in which Avr protein binds & activates the promoter of the cognate R gene [AvrBs3] (Mus musculus) PubMed
5313.
AvrBs3 binds to a conserved element in the Capsicum annuum upa20 promoter & induces gene expression through its activation domain; AvrBs3 provokes developmental reprogramming of host cells by mimicking eukaryotic transcription factors [AvrBs3] (Mus musculus) PubMed
5314.
SRE1, a gene encoding a GATA-type protein, bound to promoter sequences of genes involved in siderophore biosynthesis [Sre1] (Mus musculus) PubMed
5315.
The cloned FPPS gene carries an open reading frame of 1044-bp encoding a deduced protein of 347 amino acids with a molecular weight of 39.83 kDa, and the coding region is interrupted with a 63-bp intron [Botrytis cinerea: Farnesyl pyphosphate synthase] (Mus musculus) PubMed
5316.
BcatrA reduced sensitivity to cycloheximide and catechol, indicating that BcatrA product functions as a multidrug transporter.[BcatrA] (Mus musculus) PubMed
5317.
although IE86 does repress the UL144-mediated activation of a synthetic NFkB promoter, it is unable to block UL144-mediated activation of the CCL22 promoter, and this lack of responsiveness to IE86 appears to be regulated by binding of CREB.[viral IE86] (Mus musculus) PubMed
5318.
UL112-113 locus was able to activate the complete KSHV lytic cycle, while the UL122-123 locus, encoding the IE1 and IE2 proteins, known to be strong transactivators, did not[UL113] (Mus musculus) PubMed
5319.
These data suggest a specific pUL69-pUL97 interaction and pUL97-mediated phosphorylation which influences the regulatory activities of pUL69. [UL69] (Mus musculus) PubMed
5320.
study demonstrates that miR-UL112 targets the UL114 gene; also show that two additional HCMV-encoded miRNAs, miR-US25-1 and miR-US25-2, reduce viral replication & DNA synthesis [miR-UL112, miR-US25-1, miR-US25-2] (Mus musculus) PubMed
5321.
production, purification, and physicochemical and biochemical characterizations of a new extracellular alpha-amylolytic enzyme, ScAmy43[ScAmy43] (Mus musculus) PubMed
5322.
BGT1 was up-regulated during infection of Brassica napus leaves. [BGT1] (Mus musculus) PubMed
5323.
Sclerotinia sclerotiorum PG interacts with canola IPG-1 protein during early infection. [PG] (Mus musculus) PubMed
5324.
This is the first study to describe nucleotide and amino acid sequences of serine hydroxymethyltransferase (SHMT) from the malaria parasite Plasmodium vivax. [SHMT] (Mus musculus) PubMed
5325.
Results suggested that almost all of the observed polymorphisms were located at one surface of apical membrane antigen 1 (apical membrane antigen 1). (Mus musculus) PubMed
5326.
Crystal structures of Plasmodium vivax ADA in complex with adenosine, guanosine, and the picomolar inhibitor 2'-deoxycoformycin, are reported.[Adenosine deaminase] (Mus musculus) PubMed
5327.
This study describes the identification and characterisation of Pv38, based on the available genomic sequence of Plasmodium vivax and previous studies done with its Plasmodium falciparum homologue: Pf38. (Pv38) (Mus musculus) PubMed
5328.
Amplification of pvmdr1 and single-nucleotide polymorphisms are correlated with susceptibility of P. vivax to multiple antimalarial drugs [mdr1] (Mus musculus) PubMed
5329.
Pv41 transcription and expression during late intra-erythrocytic parasite stages were demonstrated and its subcellular localization on the parasite surface was defined. (Pv41) (Mus musculus) PubMed
5330.
frequency distribution of mutations associated with sulphadoxine-pyrimethamine resistance was investigated in pvdhfr and pvdhps genes from field isolates [dhfr and dhps] (Mus musculus) PubMed
5331.
first report of the region between interspecies conserved blocks 4 and 5 of the MSP-1 gene of P. vivax in South Korea [MSP-1] (Mus musculus) PubMed
5332.
the equilibrium unfolding, functional activity regulation and stability characteristics of Glutathione S-transferases of Plasmodium vivax [Glutathione S-transferases] (Mus musculus) PubMed
5333.
The crystal structure of PNP (purine nucleoside phosphorylase) is described and is seen to have many features in common with the previously reported structure of PNP. (PNP). (Mus musculus) PubMed
5334.
Conserved cysteine residues in NqrD and NqrE subunits are necessary for the correct folding and/or the stability of the NADH:quinone oxidoreductase complex (NqrD and NqrH). (Mus musculus) PubMed
5335.
Study used mutagenesis and suppressor analyses to identify the acyl-homoserine lactone(AHL)-binding domain of LuxN and discovered LuxN mutants that confer both decreased and increased AHL sensitivity.[LuxN] (Mus musculus) PubMed
5336.
Enzymatic analyses demonstrated that the recombinant DegQVh protein expressed in and purified from E. coli was an active serine protease whose activity required the integrity of the catalytic site and the PDZ domains.[DegQ in strain HH2] (Mus musculus) PubMed
5337.
C92, C95, and C-terminal 12 of FurVh proved to be functionally inessential. [Fur] (Mus musculus) PubMed
5338.
The crystal structure of V. harveyi luciferase bound to flavin mononucleotide (FMN)was determined, revealing a single contact between Phe272 of the alpha subunit and Tyr151 of the beta subunit, essential for activity. (luciferase alpha and beta subunit). (Mus musculus) PubMed
5339.
The crystal structure of GcnA, an N-acetyl-beta-D-glucosaminidase from Streptococcus gordonii, was solved by multiple wavelength anomalous dispersion phasing using crystals of selenomethionine-substituted protein.[GcnA] (Mus musculus) PubMed
5340.
These findings indicate that S. gordonii Hsa specifically binds to GPA and band 3, alpha2-3-linked sialic acid membrane glycoproteins.[Hsa in strain Challis DL1] (Mus musculus) PubMed
5341.
These results suggest that, in S. gordonii, mutations in glmM appear to influence bacterial cell growth and morphology, biofilm formation, and sensitivity to penicillins.[GlmM in strain DL1] (Mus musculus) PubMed
5342.
Mfa1-interacting interface of sspB antigen encompasses both the KKVQDLLKK and NITVK motif and suggest that the adherence of P. gingivalis to streptococci is driven by a protein-protein interaction domain as in the eukaryotic NR box. [sspB] (Mus musculus) PubMed
5343.
Platelet binding by GspB is a major interaction in the pathogenesis of endocarditis.[GspB] (Mus musculus) PubMed
5344.
These data suggest that S. gordonii DL1 Hsa specifically binds to three glycoproteins as receptors and that this interaction may be the initial bacterial binding step in infective endocarditis by oral streptococci.[Hsa in strain DL1] (Mus musculus) PubMed
5345.
These data suggest that S. gordonii BfrAB controls biofilm formation by regulating multiple ABC-transporter systems. [BfrA, BfrB] (Mus musculus) PubMed
5346.
GlmM contributes to the resistance to polymorphonuclear leukocytedependent killing. (Mus musculus) PubMed
5347.
SspB was crystallized using the hanging-drop vapour-diffusion method and X-ray data were collected and processed to a maximum resolution of 2.1 A with 96.4% completeness.[SspB] (Mus musculus) PubMed
5348.
X-ray diffraction data were collected from betaC-S lyases from two oral bacteria, Streptococcus anginosus and S. gordonii.[betaC-S lyase] (Mus musculus) PubMed
5349.
In medaka, dmrt I bY mediates a mitotic arrest of PGCs in males prior to testes differentiation at the sex determination stage. This occurs possibly via a cross-talk of Sertoli cells and PGCs (Mus musculus) PubMed
5350.
mRNA levels increased after temperature shift from 25 to 15 degrees C in 3 h, and then decreased rapidly to near the original level within 12 h. [CYR61] (Mus musculus) PubMed
5351.
Data show that high temperature induced DMRT1 expression in genotypic females, which was observed already from stage 36 [DMRT1] (Mus musculus) PubMed
5352.
Dmrt1a is exclusively expressed in adult testes, 50 times higher than dmrt1bY [dmrt1a; dmrt1bY] (Mus musculus) PubMed
5353.
Both Pax1 and Pax9 are indispensable for the development of the vertebral body and neural arch. (Pax1, Pax9) (Mus musculus) PubMed
5354.
primordial germ cell movements are shown to be the consequence of a combination of active SDF1a & SDF1b-guided migration; both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs[SDF1b] (Mus musculus) PubMed
5355.
The medaka fabp7 gene consists of four exons in approximately 1 kb of the genomic region with a deduced amino acid sequence that exhibits over 80% identity with those of other higher vertebrates [fabp7] (Mus musculus) PubMed
5356.
cxcr7-expressing somitic domain expanded posteriorly with its margin immediately anterior of posteriorly drifting PGCs, as if PGCs were thrusted toward the gonadal area[CSCR7] (Mus musculus) PubMed
5357.
Comparative expression analyses showed medaka hoxa2a and b2a expression in the 2nd pharyngeal arch (PA2) beyond the onset of chondrogenesis, which suggests these genes function redundantly as selector genes of PA2 identity[hoxa2a and b2a] (Mus musculus) PubMed
5358.
study identified abcb7 as the responsible gene for the nmk mutant with fatty liver; findings suggest novel roles of Abcb7 in the development of physiologically functional liver [abcb7] (Mus musculus) PubMed
5359.
CHD5 was expressed in the developing heart after stage 28. It was also detected in the developing heart at embryonic stages 28 & 35. Knocking-down of CHD5 function caused severe cardiac & ocular abnormalities. CHD5. (Mus musculus) PubMed
5360.
beta4GalT2 activity is cell-autonomously required in cells undergoing mediolateral cell intercalation, which drives extension movements during medaka gastrulation.[beta4GalT2] (Mus musculus) PubMed
5361.
results point to an important role of olSfrp5 in visual system formation and indicate that olSfrp1 and olSfrp5, despite their overlapping expression, have only partially redundant function during eye development [Sfrp5] (Mus musculus) PubMed
5362.
Lack of SeqA causes attenuation of S. enterica virulence by the oral route but not by the intraperitoneal route, suggesting a virulence defect in the intestinal stage of infection [SeqA] (Mus musculus) PubMed
5363.
These results suggest that the N-terminal region of WbaP, which contains four transmembrane domains, is essential for the insertion or stability of the protein in the bacterial membrane.[WbaP] (Mus musculus) PubMed
5364.
mutations in ramR appear to play a major role in the efflux-mediated multidrug resistance phenotype of serovar Typhimurium [ramR] (Mus musculus) PubMed
5365.
confirmed the 12-transmembrane segments topology for this Wzx, and also indicated that the C-terminus was located within the cytoplasm [serovar Typhimurium Group B, gene=Wzx] (Mus musculus) PubMed
5366.
PagN is an outer membrane protein that is a haemagglutinin and contributes to adherence to mammalian cells [PagN] (Mus musculus) PubMed
5367.
conformational dynamics of O-Acetylserine sulfhydrylase [OASS] (Mus musculus) PubMed
5368.
All four extracellular loops of PagN are crucial for invasion of mammalian cells. [PagN] (Mus musculus) PubMed
5369.
preliminary X-ray characterization of a glycerol dehydrogenase [GldA] (Mus musculus) PubMed
5370.
crystal structure of AdiC at 3.2 A resolution [AdiC] (Mus musculus) PubMed
5371.
Integration of Wnt-dependent and Wnt-independent cell fate specification pathways within the Caenorhabditis genus can occur in different ways.[SKN-1, POP-1] (Mus musculus) PubMed
5372.
data indicate that NIT2 is a central regulatory gene required for nitrate signaling on the Chlamydomonas NIA1 gene promoter and that intracellular nitrate is needed for NIT2 function and to modulate NIA1 transcript levels [NIT2] (Mus musculus) PubMed
5373.
Gsm1/Gsp1 dyads share sequence homology with and are functionally related to KNOX/BELL dyads regulating stem-cell (meristem) specification in land plants.[Gsm1] (Mus musculus) PubMed
5374.
ODA16 appears to function as a cargo-specific adaptor between IFT particles and outer row dynein needed for efficient dynein transport into the flagellar compartment.[ODA16] (Mus musculus) PubMed
5375.
This gene was first identified in a medaka mutant, and found to be mutated in primary ciliary dyskinesia patients from two affected families as well as in the pf13 mutant of Chlamydomonas [pf13] (Mus musculus) PubMed
5376.
Sporangin is synthesized at a specific stage of the Chlamydomonas cell cycle and localized to the flagella of daughter cells within the sporangial cell wall. [sporangin] (Mus musculus) PubMed
5377.
Chlamydomonas kinesin-13 (CrKinesin-13), a member of the kinesin-13 family of microtubule depolymerizing kinesins best known for their roles in the cell cycle, functions in flagellar disassembly and flagellar assembly.[kinesin-13] (Mus musculus) PubMed
5378.
In microtubule sliding assays, using axonemes containing I1 dynein but devoid of IC97, show reduced microtubule sliding velocities, revealing a critical role for IC97 in I1-dynein function and dynein-driven motility: [IC97] (Mus musculus) PubMed
5379.
A [4Fe-4S] cluster is present in the iron hydrogenase HydA and is required for in vitro activation by the HydE, HydF, and HydG maturation enzymes. (HydA). (Mus musculus) PubMed
5380.
It was concluded that REP27 plays a dual role in the regulation of D1 protein turnover by facilitating cotranslational biosynthesis insertion and activation of the nascent D1 during the photosystem II repair process. (Mus musculus) PubMed
5381.
PGRL1 in C. reinhardtii may possess a dual function in the chloroplast; that is, iron sensing and modulation of electron transfer [PGRL1] (Mus musculus) PubMed
5382.
We cloned cDNA and determined the amino acid sequence of MB7TM2 receptor. [MB7TM2] (Mus musculus) PubMed
5383.
we report a first rainbow trout NILT sequence, Onmy-NILT2D, alternatively spliced into a long membrane-bound and a short, putatively secreted form, both with the same two immunoglobulin (Ig)-like domains. [Onmy-NILT2D] (Mus musculus) PubMed
5384.
RTLL is a group VII C-type lectin with multiple isoforms that bind pathogen-associated molecular patterns such as chitin and microbial surface (Mus musculus) PubMed
5385.
in response to a viral hemorrhagic septicemia virus (VHSV) infection, the levels of expression of IL-8R are suppressed in the head kidney, spleen and muscle, in contrast to what occurs in response to Poly I:C [interleukin-8 receptor ] (Mus musculus) PubMed
5386.
Gb3 plays a role in innate immunity by cooperating with natural ligands, L-rhamnose-binding lectins[Gb3] (Mus musculus) PubMed
5387.
the cloning and characterization of the CR3 receptor beta2 (CD18) and aM (CD11b) subunits in rainbow trout [CR3 receptor] (Mus musculus) PubMed
In tissue from infected rainbow trout, there was an overall relative increase in ladderlectin compared to healthy fish and proteins were detected in extra-cellular spaces surrounding bacteria, fungi and protozoa [ladderlectin] (Mus musculus) PubMed
5390.
Genetic selection for muscle fat content in trout results in overactivation of the TOR signaling pathway-associated lipogenesis and probably also improves utilization of glucose [TOR]. (Mus musculus) PubMed
5391.
TNF-alpha1 is 1379 bp and consists of a 738 bp open reading frame (ORF) translating into a predicted protein of 246 amino acids. TNF-alpha2 is 1412 bp containing an ORF and translated protein the same lengths as TNF-alpha1 [TNF-alpha1 and TNF-alpha2] (Mus musculus) PubMed
5392.
The complete T-cell receptor alpha/delta locus of Atlantic salmon (Salmo salar) has been characterized and annotated. The genomic and expression data suggest that the salmon T-cell receptor has enormous capacity to recognize a wide diversity of antigens. (Mus musculus) PubMed
5393.
selection is playing a role in shaping diversity at the lysyl oxidase gene locus (Mus musculus) PubMed
5394.
glycosylation is not required for IFN-alpha2 antiviral activity [IFN-alpha2] (Mus musculus) PubMed
5395.
identified two closely related Tollip-encoding genes in Atlantic salmon (Salmo salar) Tollip II (Mus musculus) PubMed
5396.
the homologues of mammalian CD4 in Atlantic salmon (Salmo salar): CD4-1 with four extracellular domains and CD4-2a and CD4-2b with two extracellular domains [CD4-1 and CD4-2] (Mus musculus) PubMed
5397.
study found that loss of RAD51 function in the moss Physcomitrella patens caused a significant vegetative phenotype, indicating an important function for RAD51 in this organism [RAD51] (Mus musculus) PubMed
5398.
PprecA2 partially complemented the recA mutation in Escherichia coli and was involved in the repair of chloroplast DNA in Physcomitrella patens [PprecA2] (Mus musculus) PubMed
5399.
DCL3is required for the accumulation of 22-24 nucleotide(nt) small interfering RNAs(siRNA), but not 21 nt siRNAs. [Dcl3] (Mus musculus) PubMed
5400.
Data show that the K(m) values for beta-sitosterol of CYP710A13 and CYP710A14 were at comparable levels of those reported with higher plant CYP710A proteins: [CYP710A13 and CYP710A14] (Mus musculus) PubMed
5401.
RECA1 does not promote but rather suppresses recombination among short repeats scattered throughout the mitochondrial genome, thereby maintaining mitochondrial genome stability. (Mus musculus) PubMed
5402.
OLE1, OLE2, and OLE3 are expressed in a tissue specific manner, which can be altered via alternative splicing. [3 genes] (Mus musculus) PubMed
5403.
Plants lacking class II formins (For2) are severely stunted and composed of spherical cells with disrupted actin organization.[Formin-2] (Mus musculus) PubMed
5404.
The chitin-binding domain of chitinase A contributes to the hydrolysis of chitin in the cell-wall of S. commune.[chitinase A] (Mus musculus) PubMed
5405.
A. nidulans and A. oryzae kexB disruptants grown under hyperosmotic conditions processed a recombinant fusion protein [KexB] (Mus musculus) PubMed
5406.
The apparent K(m) and V(max) values of the enzyme for C12-NBD-ceramide were 3.32 microM and 0.085 micromol min(-1) mg(-1), respectively.[neutral ceramidase] (Mus musculus) PubMed
5407.
A Coprinopsis cinerea homokaryotic fruiting strain was mutagenised, identifying a mutant that exhibited a hyphal growth temperature sensitive defect and hyphal knot development defect at an early fruiting stage.[Smc1] (Mus musculus) PubMed
5408.
Coprinus cinereus rad50 mutants reveal an essential structural role for Rad50 in axial element and synaptonemal complex formation, homolog pairing and meiotic recombination (Mus musculus) PubMed
5409.
IraM (inhibitor of RssB activity during Magnesium starvation) and IraD (inhibitor of RssB activity after DNA damage) inhibit sigmaS proteolysis both in vivo and in vitro.[IraM and IraD] (Mus musculus) PubMed
5410.
both WfaP and WfgD are forms of UDP-Glc: GlcNAc-pyrophosphate-lipid beta-1,3-glucosyltransferases.[WfaP, WfgD] (Mus musculus) PubMed
5411.
The investigations performed showed that type II secretion in E. coli Dr+ strains leads to DraD translocation at the bacterial cell surfaces. (Mus musculus) PubMed
5412.
Overall, efficient glucosylation (IroB), transport (IroC and IroN), and processing (IroD and IroE) of salmochelins are required for avian pathogenic Escherichia coli (APEC) virulence, although IroE appears to serve an ancillary role. (Mus musculus) PubMed
5413.
These data show for the first time the efficient delivery of the autotransporter EspC protein inside the epithelial cells by EPEC, through cooperation between T5SS and T3SS. (Mus musculus) PubMed
5414.
Differences in fibronectin binding of almost 2 orders of magnitude were observed between EAEC 042 and a mutant in the AAF/II major pilin gene, aafA.[AafA] (Mus musculus) PubMed
5415.
The authors show that Cif induces not only G2, but also G1 cell cycle arrest depending on the stage of cells in the cell cycle during the infection. (Mus musculus) PubMed
5416.
EspC, a Per-activated serine protease autotransporter protein, conferred enhanced resistance on nonpathogenic E. coli.[EspC] (Mus musculus) PubMed
5417.
A new macrolide efflux protein, Mef(B), with 38% amino acid identity to Mef(A), has been characterized and represents the second member of the mef family of genes.[MefB] (Mus musculus) PubMed
5418.
We have identified a novel immunodominant cDNA clone, BmL3-helicase, encoding DEAD box RNA helicase by immunoscreening of a larval stage cDNA library of Brugia malayi. [BmL3- RNA helicase] (Mus musculus) PubMed
5419.
Cytoplasmic NAD-dependent polypropylene glycol dehydrogenase from Stenotrophomonas maltophilia was purified and characterized.[PPG-DH] (Mus musculus) PubMed
5420.
results indicate that L2 beta-lactamase charge variants give S. maltophilia a better chance of adapting and surviving in response to changes in the environment[L2] (Mus musculus) PubMed
5421.
These studies demonstrate that the Zn(2) site in L1 is very flexible and can accommodate a number of different transition metal ions.[ L1 metallo-beta-lactamase] (Mus musculus) PubMed
5422.
Phase combination plus density modification gave an interpretable map. Molecular replacement with a distantly related model foundd a dimer in the asymmetric unit & provided the correct transformation for averaging electron density between SgrAI subunits. (Mus musculus) PubMed
5423.
Extracellular proteome analysis of the wild-type and DeltaadpA strains revealed that 38 secreted proteins, including many catabolic enzymes, such as protease, glycosyl hydrolase and esterase, were produced in an AdpA-dependent manner.[AdpA] (Mus musculus) PubMed
5424.
rsmG, but not rpsL, mutants showed greater ability (two- to threefold) to produce streptomycin.[rsmG] (Mus musculus) PubMed
5425.
The findings indicate that CebR is a master regulator of cellulose/cellooligosaccharide catabolism. [CebR] (Mus musculus) PubMed
5426.
Constitutive over-expression results in an extended lifespan without impairing vital functions, suggesting a protecting role against oxidative stress. (PaMTH1, a putative methyltransferase) (Mus musculus) PubMed
5427.
The protein encoded by rpoE gene acted as a sigma factor and was sufficient to direct core RNA polymerase to the rpoE promoter. [rpoE] (Mus musculus) PubMed
5428.
Flagellar biogenesis requires RpoN2 and FliA and is temporally regulated by FlhA, FlhB, and FlgM.[RpoN2, FliA, FlhA, FlhB, FlgM] (Mus musculus) PubMed
5429.
Here, we demonstrate that the X. campestris pv. campestris Zur is involved in hypersensitive response (HR) and positively regulates the transcription of hrpA to hrpF operons and hrpX but not hrpG. [Zur] (Mus musculus) PubMed
5430.
Southern blot analysis of the 47 isolates with ToxA and ToxB probes revealed that the toxin genes were always located on different chromosomes.[ToX, ToxB] (Mus musculus) PubMed
5431.
SERK1 expression is associated with developmental change. [SERK1] (Mus musculus) PubMed
5432.
Medicago truncatula has two PISTILLATA homologues with different expression patterns and functions. RNAi silencing of MtPI and MtNGL9 affects floral development. (PI; NGL9) (Mus musculus) PubMed
5433.
Data conclude that MATE1 is an essential membrane transporter for proanthocyanidin biosynthesis in the Medicago seed coat. [MATE1] (Mus musculus) PubMed
5434.
Zoocin A has now been determined to be a d-alanyl-l-alanine endopeptidase.[zoocin A] (Mus musculus) PubMed
5435.
SeE is a novel carboxylesterase with optimal activity for acetyl esters. [SeE] (Mus musculus) PubMed
5436.
Prophage-encoded hyaluronate lyases play a more direct role in disease pathogenesis. [hyaluronate lyases] (Mus musculus) PubMed
5437.
Twenty-four S. equi subsp. zooepidemicus strains were analyzed to determine the genetic difference among three previously characterized as zoocin A producers (strains 4881, 9g, and 9h) and the 21 nonproducers.[Zoocin A, Zif] (Mus musculus) PubMed
5438.
These data show that Zif is a novel FemABX-like immunity factor because it provides resistance to a bacteriolytic endopeptidase by lengthening the peptidoglycan cross bridge.[Zif] (Mus musculus) PubMed
5439.
Purple acid phosphatase-like sequences in prokaryotic genomes and the characterization of an atypical purple alkaline phosphatase from Burkholderia cenocepacia J2315 (Mus musculus) PubMed
5440.
expression of E6 increased primary human keratinocytes cell adhesion [HPV16 E6 oncoprotein] (Mus musculus) PubMed
5441.
UV radiation and wounidng enahnces HPV8 E6 expression and skin tumor development. [HPV8 E6] (Mus musculus) PubMed
5442.
Later embryos and larvae of amphioxus express AmphiLim1/5 in clusters of cells, probably motoneurons, in the anterior part of the central nervous system, in the hindgut, in Hatschek's right diverticulum [LIM-homeobox gene, AmphiLim1/5] (Mus musculus) PubMed
5443.
PpNCED1 and VVNCED1 initiate ABA biosynthesis at the beginning of fruit ripening, and that ABA accumulation might play a key role in the regulation of ripeness and senescence of both peach and grape fruits.[VvNCED1] (Mus musculus) PubMed
5444.
The BTL was expressed during the last maturation stages in both skin and pulp tissues and exhibited an apparent molecular mass of c. 31 kDa. [BTL] (Mus musculus) PubMed
5445.
Mutants in the rpoE gene that suppress the mutation of the most conserved residue A-30G of the rpoEp3 promoter, were identified.[Sigma E] (Mus musculus) PubMed
5446.
FliK length variants produce flagellar rods with lengths proportional to the corresponding FliK molecular size, suggesting that FliK controls the length of not only the hook but also the rod. (Mus musculus) PubMed
5447.
The negative regulatory effect of iron on clyA expression is mainly at translational level. (Mus musculus) PubMed
5448.
unique dual activity amino acid hydroxylase;TgAaaH1, is constitutively expressed while the other gene, TgAaaH2, is induced during formation of the bradyzoites of the cyst stages of the life cycle [TgAaaH1; TgAaaH2;] (Mus musculus) PubMed
5449.
Herein, we report the presence of PREX (DNA primase, DNA helicase and DNA polymerase activities), a P. falciparum orthologue in Toxoplasma gondii. [PREX] (Mus musculus) PubMed
5450.
FtsH1 undergoes processing events to remove both the N- and C-termini. [FtsH1] (Mus musculus) PubMed
5451.
This study supports for the first time that type 2C protein phosphatase is an important regulator of cell growth in Toxoplasma gondii.[PP2C] (Mus musculus) PubMed
5452.
Data present a structural model for the inhibition of TgCPL by LHVS and possible roles for TgCPL as a protease involved in the degradation or proteolysis of parasite proteins involved in invasion: [TgCPL] (Mus musculus) PubMed
5453.
The X-ray structure of the yeast aquaporin Aqy1 from Pichia pastoris at 1.15 A resolution, is presented.[Aqy1] (Mus musculus) PubMed
5454.
two novel serotonin transporter gene transcripts, SmSERT-A and SmSERT-B, from S.mansoni [SmSERT-A][SmSERT-B] (Mus musculus) PubMed
5455.
eIF4E binds to m(7)G and m(2,2,7)G caps with similar specificity. [eIF4E] (Mus musculus) PubMed
5456.
On the Na(+)-driven flagellar motor of Vibrio alginolyticus, FliG copurified with the basal bodies. Data detect FliG on the MS ring surface of the basal bodies. [FliG] (Mus musculus) PubMed
5457.
PF-8 forms a head-to-head dimer in the form of a C clamp, with its concave face containing a number of basic residues that are predicted to be important for DNA binding.[PF-8] (Mus musculus) PubMed
5458.
Using large-scale cloning analysis on EBV-positive nasopharyngeal carcinoma cells, two novel EBV miRNA, now named miR-BART21 and miR-BART22, were identified (Mus musculus) PubMed
5459.
Highly purified and immunoreactive intimin has been successfully obtained, which can adhere to the surface of HEp-2 cells. [intimin] (Mus musculus) PubMed
5460.
Data discovered that Zur controls a cluster of genes predicted to direct synthesis of an uncharacterized siderophore-related non-ribosomally encoded peptide designated coelibactin. [Zur] (Mus musculus) PubMed
5461.
WhiD is a soluble protein containing a single [4Fe-4S](2+) cluster ligated by four cysteines. [WhiD] (Mus musculus) PubMed
5462.
alpha-amylase isoform I-1 degrades starch granules in living rice cells, and Contains a plastid-targeting signal common to both rice and onion cells. [AmyI-1] (Mus musculus) PubMed
5463.
Overexpression of OsGLK1 promoted transcription of a set of nucleus-encoded genes related to chloroplast functions and plastid-encoded genes. [GLK1] (Mus musculus) PubMed
5464.
report here the identification and expression analysis of a novel rainbow trout IL-20L molecule that is phylogenetically related to IL-19, IL-20 and IL-24, and its expression is modulated by different cytokines[IL-20-like protein] (Mus musculus) PubMed
5465.
[Pax6] results show that the strongly conserved features of Pax6 expression through forebrain development shared by all amniote vertebrates are also present in the anamniote amphibians as a common characteristic of the forebrain organization of tetrapods (Mus musculus) PubMed
5466.
established that methionine sulfoxide reductase A-1 expression decreases during aging and is regulated by the DAF-16/FOXO3a transcription factor.[FOXO3a] (Mus musculus) PubMed
5467.
The centrosomal localization of Diversin is crucial for its function in Wnt signaling.[Diversin] (Mus musculus) PubMed
5468.
P-protein undergoes microtubules (MT)-inhibited import, with the mode of MT-interaction being regulated by the oligomeric state of the P-protein.[P-protein] (Mus musculus) PubMed
5469.
A deletion in the stalk of the NA, a feature observed during the process of adaptation of influenza viruses from wild aquatic birds to poultry, favors viral replication and enhances pathogenesis in chickens. (Mus musculus) PubMed
5470.
Early gene, hhi1, identified as the gene, or one of the genes, responsible for viral reactivation. [hhi] (Mus musculus) PubMed
5471.
AAV5 ensures the production of a Rep40-like protein by utilizing a novel internal translation initiation event.[Rep40-like protein] (Mus musculus) PubMed
5472.
BRITTLE CULM 5 mutants have reduced secondary cell wall thickness in the nodes, and the cell wall composition was specifically altered in the nodes. [bc5] (Mus musculus) PubMed
5473.
Overexpression of APX in the mitochondria prevents cells from oxidative stress and cellular death. [Apx] (Mus musculus) PubMed
our results demonstrate that apoptosis of HSV-1-infected iDCs requires both c-FLIP downregulation and diminished expression of viral latency-asociated transcript. (LAT) (Mus musculus) PubMed
5476.
crystal structure of Escherichia coli FocA at 2.25 A resolution [FocA] (Mus musculus) PubMed
5477.
FEN1 gene of a model legume, Lotus japonicus, overcomes the lack of NifV in rhizobia for symbiotic nitrogen fixation [fen1] (Mus musculus) PubMed
5478.
fitness of the npq4 mutant in a shifting light environment is reduced compared to wild-type cells, demonstrating that LHCSR is required for survival in a dynamic light environment [npq4] (Mus musculus) PubMed
5479.
data indicate that Tipin/Tim1/And1 form a complex that links stabilization of replication fork and establishment of sister chromatid cohesion [And1] (Mus musculus) PubMed
5480.
Polar transport of indole-3-acetic acid synthesized at the tip region is regulated by ZmPIN1. [PIN1] (Mus musculus) PubMed
5481.
Data report a diSUMO-like protein that appears to be essential for nuclei segregation and positioning, the prerequisite for cell specification during FG maturation. [DiSUMO-like] (Mus musculus) PubMed
5482.
OdsH encodes protein localizing to evolutionarily dynamic loci in heterochromatin & leads to decondensation; in male hybrids, D mauritiana OdsH acts as sterilizing factor by associating with heterochromatic Y of D simulans; D simulans OdsH does not [OdsH] (Mus musculus) PubMed
5483.
[PomA-PomB stator complex] Aspartate24 and at least two other carboxylates constitute sodium ion interaction sites in the PomA-PomB supramolecular motor complex. (Mus musculus) PubMed
5484.
The structure of TrxR was homodimeric with both NADPH- and flavin adenine dinucleotide (FAD)-binding domains containing variants of the canonical nucleotide binding fold, the Rossmann fold. It can utilize only NADPH for activity. [TrxR] (Mus musculus) PubMed
5485.
Purified skeletal ryanodine receptors are similarly activated by purified triadin or purified junctin added to their luminal side, although a lack of competition indicated that the proteins act at independent sites.[RyR1] (Mus musculus) PubMed
5486.
Lsi6 is a silicon transporter responsible for intervascular transfer in the node. [Lsi6] (Mus musculus) PubMed
5487.
TDR possibly plays crucial regulatory roles in several basic biological processes during rice pollen development.[TDR] (Mus musculus) PubMed
5488.
revealed intact omTLR7 and omTLR8a1 open reading frames (ORFs) located on chromosome 3 and a second locus on chromosome 22 that contains an omTLR8a2 ORF and a putative TLR7 pseudogene.[TLR7, TLR8a1 and TLR8a2] (Mus musculus) PubMed
5489.
Rab5 and Rab7 occur on different but partly overlapping endosome populations. Rab7 but not Rab5 occurs on symbiosome membranes. [Rab5; Rab7] (Mus musculus) PubMed
5490.
Data show that betaine aldehyde dehydrogenase OsBADH1 catalyzes the oxidation of acetaldehyde efficiently, while the activity of OsBADH2 is extremely low: [OsBADH1 and OsBADH2] (Mus musculus) PubMed
5491.
NeuO expression led to a reduced biofilm formation in biofilm positive E. coli K1 isolates (NeuO). (Mus musculus) PubMed
5492.
crystal structure of recombinant Lmb, a laminin-binding adhesin from Streptococcus agalactiae, has been determined at 2.5 A resolution.[laminin-binding adhesin] (Mus musculus) PubMed
5493.
HI-LOX is a chloroplast-localized type 2 13-lipoxygenase gene involved in herbivore-induced jasmonic acid biosynthesis. [HI-LOX] (Mus musculus) PubMed
5494.
present the catalytic properties and the structure of SH from X. campestris pv. campestris (SC) in the resting apo state with an empty active site (apo SC).[sucrose hydrolase] (Mus musculus) PubMed
5495.
AMPK signalling in response to mitochondrial dysfunction enhances Legionella proliferation in host cells.[AMPK] (Mus musculus) PubMed
5496.
BmToll9 is possibly involved in the local gut immune response.[Toll9] (Mus musculus) PubMed
5497.
the N-terminal domain of Vsr changes its conformation as a result of DNA nicking, and DNA Pol I releases Vsr from the nick by reversing that conformational change [vsr] (Mus musculus) PubMed
5498.
Resistance to apramycin in these isolates was closely related to aac(3)-IV gene. [aac(3)-IV] (Mus musculus) PubMed
5499.
The aim of this study was to assess early preconditioning protection against stunning in conscious sheep and analyze the role of ATP-dependent potassium (KATP) channels in the protective mechanism.[mKATP, sKATP] (Mus musculus) PubMed
5500.
The identification of a mitochondrial-type monothiol glutaredoxin in the mitosomes of G. intestinalis thus completes the mitosomal FeS cluster biosynthetic pathway and provides further evidence for the mitochondrial origin of these organelles. (Mus musculus) PubMed
5501.
NMR assignment of the FK506-binding domain of PvFKBP35 [FKBP35] (Mus musculus) PubMed
5502.
OsENOD93-1 is an early nodulin gene expressed in vascular bundles, as well as in epidermis and endodermis. Transgenic plants accumulated higher concentrations of total amino acids and total N in roots. [OsENOD93-1] (Mus musculus) PubMed
5503.
differences in cry2 mRNA cycling between Ae. aegypti and Cx. quinquefasciatus suggest a potential role for this mammalian-like cryptochrome in the control of mosquito activity patterns[cry2] (Mus musculus) PubMed
5504.
The OsLRR1 protein interacts with the plasma membrane-localized O. sativa hypersensitive-induced response protein 1. Expression of OsLRR1 in transgenic plants enhances resistance to P. syringae. [OsLRR1; OsHIR1] (Mus musculus) PubMed
5505.
We demonstrate the interaction of PfeIF4G with PfeIF4E, PfeIF4A (PfH45) and PfPABP. [Eif4G] (Mus musculus) PubMed
5506.
Data show that an ACE2-Ang-(1-7)-AT(7)R pathway modulates Ang II-dependent ROS formation within the nucleus, providing a protective mechanism against oxidative stress and cell damage: [ACE2 and AT(7)R] (Mus musculus) PubMed
5507.
(1)H, (15)N, and (13)C assignments for the ferric (low-spin, S = (1/2)) protein with a b heme cofactor and after post-translational modification leading to a c-like heme. [hemoglobin] (Mus musculus) PubMed
5508.
complete resonance assignment of Plasmodium falciparum thioredoxin in its oxidized form by heteronuclear multidimensional spectroscopy [thioredoxin] (Mus musculus) PubMed
5509.
NMR assignments for the second microneme adhesive repeat of the microneme protein 3 of E. tenella [MIC3] (Mus musculus) PubMed
complete NMR chemical shift assignments of Cqui-OBP1 bound to the MOP pheromone obtained at pH 7.0 and 25 degrees C [OBP1] (Mus musculus) PubMed
5512.
study of changes in ryanodine receptor (RYR) expression and subcellular localization as result of temperature acclimation [ryr] (Mus musculus) PubMed
5513.
Tbj1, was heterologously expressed, purified, and found to exist as a compact monomer in solution; findings indicated that while Tbj1 did not possess independent chaperone activity, it potentially functioned as a novel co-chaperone of Hsp70 [Tbj1] (Mus musculus) PubMed
5514.
The characterization of PadA and its interaction with human platelets at the fibrinogen receptor GPIIbIIIa are reported.[PadA] (Mus musculus) PubMed
5515.
The adrenergic sensors QseC and QseE were not required for norepinephrine (NE)-enhanced enteritis, intestinal colonization of calves, or NE-dependent growth in culture media and did not influence virulence factors.[QseE] (Mus musculus) PubMed
5516.
A review of of the main functions of DegP and DegS in stress sensing, regulation and protection during the unfolded protein response (DegP and DegS). (Mus musculus) PubMed
5517.
review summarizes current knowledge about the molecular mechanisms and multiple signal integration in sigma(S)(RpoS) degradation (RpoS). (Mus musculus) PubMed
5518.
The segmental duplication of Opaque-2 gene is not only found in rice, but also in sorghum, which split from maize 11.9 million years ago.[Opaque-2] (Mus musculus) PubMed
5519.
These results indicate that OsPBP1 is a novel functional C2-domain phospholipids-binding protein that is required for pollen fertility likely by regulating Ca(2+) and phospholipid signaling pathways.[PBP1] (Mus musculus) PubMed
5520.
We here describe the sequencing of the gene coding for the PDI from P. chabaudi and analyse the relationship to its counterpart enzymes, particularly with the PDI from other Plasmodium species.[protein disulfide isomerase] (Mus musculus) PubMed
5521.
no association between low-armour Eda allele and preference for freshwater over saltwater[Ectodysplasin] (Mus musculus) PubMed
5522.
The segmental duplication of Opaque-2 gene is not only found in rice, but also in sorghum, which split from maize 11.9 million years ago.[Opaque-2] (Mus musculus) PubMed
5523.
MprF represents a new class of lipid-biosynthetic enzymes with two separable functional domains that synthesize Lys-PG and facilitate Lys-PG translocation.[Staphylococcus aureus SA113, MprF] (Mus musculus) PubMed
5524.
ICP27 and UL47 jointly displace Paip2 from PABP, and did not alter translation efficiency of transfected reporter RNAs but modulated transcript abundance and expression [ICP27] (Mus musculus) PubMed
5525.
(1)H, (15)N and (13)C backbone chemical shift assignments for the Psb27 protein of Photosystem II from Synechocystis PCC 6803 [Psb27] (Mus musculus) PubMed
5526.
Data show that the crystallographic temperature factors for phosphoenolpyruvate sugar phosphotransferase system EI are lower for the HPr binding domain in contact with the P-His domain and higher for EIC: [EI] (Mus musculus) PubMed
5527.
Data indicate that TvMST has a k(cat)/K(m) for reduced thioredoxin of 6.2 x 10(7) m(-1) s(-1), suggesting that thioredoxin is a preferred substrate for TvMST: [TvMST) (Mus musculus) PubMed
5528.
The KIF9A and KIF9B genes are strongly associated with the flagellar skeleton and participate in flagellar motility. (Mus musculus) PubMed
5529.
Thrombospondin-related sporozoite protein (TRSP) is an additional thrombospondin type 1 repeat (TSR)-containing malaria parasite protein that is mainly involved in initial infection of the mammalian host. [TRSP] (Mus musculus) PubMed
5530.
We report the discovery and characterization of MISFIT, the first protein with paternal effect on the development of the rodent malaria parasite Plasmodium berghei in Anopheles mosquitoes. (Mus musculus) PubMed
5531.
Identification of a functionally important loop in Salmonella typhimurium ArnT (Mus musculus) PubMed
5532.
Gamma-glutamylcysteine synthetase has been analysed in the asexual erythrocytic stages of rodent malaria parasite, Plasmodium berghei and its host erythrocytes. [gamma GCS] (Mus musculus) PubMed
5533.
Bqt3 and Bqt4 are inner nuclear membrane proteins required for chromosomal bouquet formation. [2 genes] (Mus musculus) PubMed
5534.
OsPra2 protein was localized in the membrane and nucleus of the cell. Overexpression caused a dwarf phenotype. [Pra2] (Mus musculus) PubMed
5535.
Macrophage inhibitory factor (MIF) expression was induced by oxidized LDL in vascular smooth muscle via a NF-kappaB dependent manner. (Mus musculus) PubMed
5536.
organization of the T cell receptor beta locus resembles that seen in mammals; there are 51 V segments, a single D segment, 27 Jbeta1 segments, a single Jbeta2 segment, and two constant regions. (Mus musculus) PubMed
5537.
AphB activates the expression of two virulence regulators, ToxR and TcpP, which together control the expression of the master virulence regulator ToxT. [AphB] (Mus musculus) PubMed
5538.
Many genes of flavonoid biosynthesis were down-regulated in a tissue-specific manner in M. truncatula lines harboring retrotransposon insertions in the MtWD40-1 gene. [WD40-1] (Mus musculus) PubMed
5539.
The thermodynamics and kinetics of wild-type and mutant HTLV-1 nucleocapsid/nucleic acid interactions, were quantified.[Nucleocapsid] (Mus musculus) PubMed
5540.
These results indicate that MutT specifically recognizes 8-oxoguanine nucleotides by the ligand-induced conformational change.[MutT] (Mus musculus) PubMed
5541.
Transcriptional functionality of duplicated genes, challenging the dogma of mutually exclusive var gene transcription and suggesting mechanisms behind antigenic variation of var2csa genes, is demonstrated.[var2csa] (Mus musculus) PubMed
5542.
UDP-N-acetylgalactopyranose mutase (UNGM), has relaxed specificity and can use either UDP-Gal or UDP-GalNAc as a substrate.[UNGM] (Mus musculus) PubMed
5543.
Hatching enzyme space group was assigned as primitive orthorhombic P2(1)2(1)2(1), with unit-cell parameters a = 32.9, b = 62.5, c = 87.4 A. The crystal contained one ZHE1 molecule in the asymmetric unit[ZHE1] (Mus musculus) PubMed
5544.
(PSD-95)PSD-95 family members at nicotinic synapses on chick ciliary ganglion neurons in culture execute multiple functions to enhance transmission. (Mus musculus) PubMed
5545.
purification, crystallization & preliminary crystallographic analysis of VanG in complex with ADP are reported. The crystal belonged to space group P3(1)21, with unit-cell parameters a=b=116.1, c=177.2A, & contained 2 molecules in asymmetric unit[VanG] (Mus musculus) PubMed
5546.
Periconceptional undernutrition and twinning may result in the alterations of placental 11betaHSD1/2 activities at particular times during gestation, influencing fetal hypothalamic-pituitary-adrenal function. (Mus musculus) PubMed
5547.
Molecular details of the interaction between the semiquinone radical and the nitrate reductase A environment have been provided.[NarG, NarH, NarI] (Mus musculus) PubMed
5548.
chemical basis for mistranslation of serine for alanine by AlaRS [AlaRS] (Mus musculus) PubMed
5549.
NMT depletion in trypanosomes causes avirulence and endocytic defects. [NMT] (Mus musculus) PubMed
5550.
The ICP27 RGG box is unique in its recognition of nucleic acid sequences compared to other RGG box proteins; it prefers flexible, GC-rich substrates that do not form stable secondary structures (ICP27). (Mus musculus) PubMed
5551.
The 2.95 A resolution X-ray crystal structure of APS kinase reported here revealed a hexameric assembly with D3 symmetry.[APS kinase] (Mus musculus) PubMed
5552.
show that Tyt1 reconstituted in proteoliposomes is strictly dependent on the Na(+) gradient and is stimulated by an inside negative membrane potential and by an inversely oriented proton gradient. [ Tyt1 ] (Mus musculus) PubMed
5553.
Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae (Mus musculus) PubMed
5554.
Partial depletion of ALD and GAPDH was sufficient to rapidly kill the trypanosomes. [ALD, GAPDH] (Mus musculus) PubMed
5555.
GK3 gene are up-regulated by acclimation to 5 degrees C in diapause eggs. [GK3] (Mus musculus) PubMed
5556.
CDC16 is one of the key mediators in controlling the overall number of lateral roots and nodules. [CDC16] (Mus musculus) PubMed
5557.
CYP51 bound to 4 standard fungicides and to 14 XF-synthetic fungicide compounds. [CYP51] (Mus musculus) PubMed
5558.
Deleterious mutations in the LjRHL1 gene, encoding a basic helix-loop-helix (bHLH) transcription factor, were responsible for the lack of root hairs in the L. japonicus Ljrhl1-1 mutant. [RHL1] (Mus musculus) PubMed
5559.
Trypanothione reductases from T. brucei and T. cruzi are highly similar based on structural, kinetic and inhibitor studies. [trypanothione reductase] (Mus musculus) PubMed
5560.
LIN is an E3 ubiquitin ligase containing highly conserved U-box and WD40 repeat domains, and is a regulator of nodulation factor signal transduction pathway. [LIN] (Mus musculus) PubMed
5561.
The structure of M2 was solved by three different groups, using different techniques, protein sequences and pH environment.[M2] (Mus musculus) PubMed
5562.
Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition. (Mus musculus) PubMed
5563.
examined the functions of the non-duplicated KlSir2 and found that it interacts with both KlSir4 and KlSum1.[Sum1] (Mus musculus) PubMed
5564.
The GTP-binding motif of FlhF is important for polar localization of the flagellum but not for the interaction with FlhG.[FlhF] (Mus musculus) PubMed
5565.
The results suggested that the assembly characteristics of EcFtsZ and MtbFtsZ are different and indicated that the assembly dynamics of these proteins are regulated by different mechanisms.[FtsZ] (Mus musculus) PubMed
5566.
Loss of CAP5.5 and CAP5.5V lead to the loss of protein from the posterior cell-end, organelle mis-positioning giving rise to aberrant cytokinesis, and disorganisation of the sub-pellicular microtubules that define trypanosome cell shape.[CAP5.5, CAP5.5V] (Mus musculus) PubMed
5567.
H94 in the input domain of ArsS is crucial for acid perception in H. pylori 26695 [ArsS] (Mus musculus) PubMed
5568.
First structural insights into a full-length ROSE element are provided by examining the temperature-induced conformational changes of ROSE(ibpA).[ibpA] (Mus musculus) PubMed
5569.
The channel-forming capability of recombinant expressed, affinity-purified PorA and PorH proteins of C. glutamicum revealed that the channels consisted solely of these two components. [porH] (Mus musculus) PubMed
5570.
CadB only acts as a lysine-cadaverine antiporter but also mediates cadaverine uptake at alkaline pH to result in cell protection from superoxide stress. [CadB] (Mus musculus) PubMed
5571.
Suggest a novel Na(+)/NH(4)(+) exchange pathway in apical membranes of mitochondrion-rich cells of medaka involving slc913, Rhcg1 and Rhbg. (Mus musculus) PubMed
5572.
These results show that bovine viral diarrhea virus NS4B is an integral membrane protein associated with the Golgi apparatus and virus-induced membranes, the putative site for BVDV genome replication. (Mus musculus) PubMed
5573.
NS5A protein directly interacts with endogenous beta-catenin and colocalizes with beta-catenin in the cytoplasm. (NS5A protein) (Mus musculus) PubMed
5574.
The data show that ORF3 is dispensable for Porcine circovirus type 2 replication in pigs.[ORF3] (Mus musculus) PubMed
5575.
TAR1 mediation of temperature-associated repression of LAC1 suggests a novel mechanism of laccase regulation and a new function for Nmr proteins.[TAR1] (Mus musculus) PubMed
5576.
Results suggest that TcUBP1 could be linking the mRNA metabolism at both sides of the nuclear pore complex, using the RRM as a nuclear localization signal, and being exported as a cargo on mRNA. (Mus musculus) PubMed
5577.
RTA expression which controls viral reactivation from latency, was regulated by a virus-encoded microRNA. [RTA] (Mus musculus) PubMed
5578.
the membrane topology of LolC and LolE proteins [LolC][LolE] (Mus musculus) PubMed
5579.
Data show that the high-resolution structure of the adenylation domain of Staphylococcus aureus NAD(+)-dependent DNA ligase establishes the conserved domain architecture with other bacterial adenylation domains [ligA] (Mus musculus) PubMed
5580.
A recombinant His-tagged portion of the extracellular domain of the Staphylococcus aureus serine/threonine kinase Stk1, containing three PASTA subunits, has been crystallized [Stk1]. (Mus musculus) PubMed
5581.
Results deascribe the expression, purification, crystallization and preliminary X-ray analysis of the NADPH-dependent aldo-keto reductase conjugated polyketone reductase C2 from Candida parapsilosis. (Mus musculus) PubMed
5582.
The binding of purified GlxR, RamA and RamB was verified by electrophoretic mobility shift assays and the regulatory effects of these proteins on sdhCAB gene expression were tested.[sdhC, RamA, GlxR] (Mus musculus) PubMed
5583.
We have shown the participation of a novel transcript (named somitovasculin) in circulatory vessel development (Mus musculus) PubMed
5584.
CATP-5 represents the first P(5)-type ATPase that is associated with the plasma membrane, being expressed in the apical membrane of intestinal cells and the excretory cell. (CATP-5) (Mus musculus) PubMed
5585.
High frequency oscillatory ventilation combined with exogenous pulmonary surfactant can decrease the concentration of caspase-3 and p73 rabbit with acute respiratory failure. [p73] (Mus musculus) PubMed
Expression of protocadherin 9 in the nervous system of the embryonic zebrafish (Mus musculus) PubMed
5588.
RA68 is required for postmeiotic pollen development. (Mus musculus) PubMed
5589.
Functional 3c protein expression is crucial for feline coronavirus replication in the gut. [3C] (Mus musculus) PubMed
5590.
The complex of KfiA and KfiC has polymerase activity to synthesize N-acetylheparosan. [KfiC][KfiA] (Mus musculus) PubMed
5591.
PpoC from Aspergillus nidulans is a fusion protein with only one active heme (Mus musculus) PubMed
5592.
Characterization of the restriction enzyme-like endonuclease encoded by the Entamoeba histolytica non-long terminal repeat retrotransposon EhLINE1 (Mus musculus) PubMed
5593.
the crystal structures of dimeric TftC and tetrameric TftD [TftD][TftC] (Mus musculus) PubMed
5594.
Alanine aminotransferase of Trypanosoma brucei--a key role in proline metabolism in procyclic life forms (Mus musculus) PubMed
5595.
Data show that Greatwall is activated during M phase by Cdk1/cyclin B (MPF), but once activated, Gwl promotes PP2A/B55delta inhibition with no further requirement for MPF. (Mus musculus) PubMed
5596.
GalNAc-P-P-Und is synthesized reversibly by a novel GlcNAc-P-P-Und epimerase after the formation of GlcNAc-P-P-Und by WecA in E. coli O157. [Z3206] (Mus musculus) PubMed
5597.
Our experimental results at physiological pH and computational analyses reveal that amino acid residues in transmembrane segment II contribute to the cation pathway of NhaA and its pH regulation. [NhaA] (Mus musculus) PubMed
5598.
analysis of the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I) (Mus musculus) PubMed
5599.
the first structure of a eukaryotic microsomal 14DM that acts on sterol biosynthesis [sterol 14alpha-demethylase] (Mus musculus) PubMed
5600.
These results suggest that Rnd1/3 are required for Xenopus somitogenesis. (Rnd1 and Rnd2) (Mus musculus) PubMed
5601.
fzd6 are broadly expressed throughout the head, during zebrafish craniofacial development (Mus musculus) PubMed
5602.
ticrr acts in association with TopBP1 and plays an essential role in preinitiation complex formation [ticrr = TopBP1-interacting, checkpoint, and replication regulator] (Mus musculus) PubMed
5603.
Btbd6a promotes the relocation of Plzf from nucleus to cytoplasm and targets Plzf for ubiquitination and degradation (Mus musculus) PubMed
5604.
Heparan sulfate functions as a factor that promotes the binding of BAEBL and merozoite invasion. [BAEBL] (Mus musculus) PubMed
5605.
study reports identification and characterization of an insect farnesol dehydrogenase (AaSDR-1) that oxidizes farnesol into farnesal, a precursor of juvenile hormone , in the corpora allata [farnesol dehydrogenase (AaSDR-1)] (Mus musculus) PubMed
5606.
The data show that the porcine reproductive and respiratory syndrome E (envelope) protein myristoylation is non-essential for PRRSV infectivity but promotes the growth of the virus. (Mus musculus) PubMed
5607.
pM140 protects its binding partner, pM141, from ubiquitin-independent proteasomal degradation. Protection is conferred by a stabilization domain mapping to amino acids 306 to 380 within pM140. (pM140 and pM141) (Mus musculus) PubMed
5608.
These data suggest that PyMIF modulates host immune responses together with host MIF and has potential to prolong parasitemia or the chronicity of malaria infection.[MIF] (Mus musculus) PubMed
5609.
IDEF1 coordinately regulates the expression of iron deficiency-responsive genes related to iron acquisition and utilization during the early stage of iron deficiency. [IDEF1] (Mus musculus) PubMed
5610.
[E2 glycoprotein] Sequestering E2 into E7-E2 oligomers provides a possible additional route to uncontrolled E7 expression, in addition and prior to the disruption of the E2 gene during viral integration into the host genome. (Mus musculus) PubMed
5611.
pre-tRNA binding affinities for Bacillus subtilis and Escherichia coli RNase P are enhanced by sequence-specific contacts between the fourth pre-tRNA nucleotide on the 5' side of the cleavage site and the RNase P protein subunit.[Rnase P] (Mus musculus) PubMed
5612.
Properties of intragenic suppressor strains lead us to postulate that the C-terminal tail facilitates an oscillation of transmembrane-spanning segment 5 that is required for coordinated pore function and high AmtB activity. [AmtB] (Mus musculus) PubMed
5613.
A new Plasmodium falciparum erythrocyte binding protein that appears to be located in the micronemes of the merozoite stage of the parasite and membrane linked through a glycosylphosphatidylinositol (GPI) anchor, was identified.[GAMA] (Mus musculus) PubMed
5614.
TUP1 has pathobiological significance and plays both conserved and distinct roles in serotype A and D strains of C. neoformans.[Tup1] (Mus musculus) PubMed
5615.
These data establish the direct role of Clp in the response to fluctuating c-di-GMP levels and depict a novel mechanism by which quorum sensing links the second messenger with the X. campestris pv. campestris virulence regulon.[Clp] (Mus musculus) PubMed
5616.
Protein kinases A and C regulate receptor-mediated increases in cAMP in rabbit erythrocytes [protein kinase A and protein kinase C]. (Mus musculus) PubMed
5617.
The data suggest that L protein is required for virus growth in J774-1 cells and also suggest that the site responsible for virus growth in those cells, is the acidic domain of L protein. (Mus musculus) PubMed
5618.
Results identify proteins that are substrate candidates for the DsbA disulfide oxidoreductase as well as being responsible for the virulence attenuation of the dsbA mutant. (Mus musculus) PubMed
5619.
Data establishes functional groups of genes controlling different regulatory phases, including Ath5 expression at cell-cycle exit and its down-regulation prior to terminal RGC differentiation: [Ath5] (Mus musculus) PubMed
5620.
genetic evidence that AmtB inactivation depends on the essential protease HflB, which appears to cause inactivation not as a protease but as a chaperone [HflB][AmtB] (Mus musculus) PubMed
5621.
These results show that SigB may positively influence the appearance of Staphylococcus aureus small-colony variants and the production of biofilm upon aminoglycoside exposure. (Mus musculus) PubMed
5622.
Recombinant SSL10 inhibited the binding of complement component C1q to IgG-Sepharose and hemolysis of IgG-sensitized sheep erythrocytes via the classical complement activation pathway.[SSl10] (Mus musculus) PubMed
5623.
most active and enantioselective mutants retain the high thermostability of the parent WT phenylacetone monooxygenase. [Phenylacetone Monooxygenase] (Mus musculus) PubMed
5624.
Lr10-mediated leaf rust resistance depends on the RGA2 gene. [Lr10; RGA2] (Mus musculus) PubMed
5625.
Episomal overexpression of EhADH3 in E. histolytica in only subtle increase of virulence in animal models of amebic colitis and amebic liver abscess, making it difficult to directly link EhADH3 levels to virulence.[ADH3] (Mus musculus) PubMed
5626.
Comparative studies in the cytokine response between Equine infectious anemia virus and its S2 deletion mutant infection revealed that S2 enhances the expression of IL-1alpha, IL-1beta, IL-8, MCP-2, MIP-1beta, IP-10 and IL-34. (Mus musculus) PubMed
5627.
Data show thaT FLR-2 acts as a signaling molecule for the neural control of intestinal functions, which is achieved in a functional network involving class 1 and class 2 flr genes as well as ghi-1: [ghi-1] (Mus musculus) PubMed
5628.
Thus, our data suggest that Kv3.1b expression occurs with the onset of functional synaptogenesis, while a different signal, absent from cultures of dissociated auditory brain stem, is needed for Kv1.1 expression.(KV3.1) (Mus musculus) PubMed
5629.
Phosphate carrier is the phosphate sensor in YMUC and contributes to the structure of this channel.[YMUC] (Mus musculus) PubMed
5630.
Suggest that urotensin-II normally acts as a pulmonary vasodilator after birth, but in the presence of meconium aspiration syndrome, it assumes a vasoconstrictor role. (Mus musculus) PubMed
5631.
crystallographic structures of two mutant effector domains, W187Y and W187A, of influenza A/Udorn/72 virus NS1 effector [NS1] (Mus musculus) PubMed
5632.
Description of a unique PNPase mediated processing pathway for tRNALeu5 that is distinct from all previously reported RNase E and RNase P dependent tRNA processing pathways (leuX). (Mus musculus) PubMed
5633.
study reports a single nAChR gene (Agamalphabeta9) generating both alpha and non-alpha subunits by alternative splicing [nicotinic acetylcholine receptor, Agamalphabeta9] (Mus musculus) PubMed
5634.
The endogenous abscissic acid concentration of enf1 was lower than that of wild-type seedlings and the nitrogen fixation activity of abamine-treated plants was elevated to the same levels as enf1.[Enf1] (Mus musculus) PubMed
5635.
The activation of TLD1 reduced the IAA maxima at the lamina joint, shoot base, and nodes, resulting in subsequent alterations in plant architecture and tissue patterning but enhancing drought tolerance.[TLD1] (Mus musculus) PubMed
5636.
Data show that protein kinase CIPK15 [calcineurin B-like (CBL)-interacting protein kinase] plays a key role in O(2)-deficiency tolerance: [CIPK15] (Mus musculus) PubMed
5637.
The structure of the cytosolic portion of MgtE (residues 6-262) was determined at 2.2 A resolution by the single-wavelength anomalous dispersion method. [MgtE] (Mus musculus) PubMed
5638.
The present study examined the expression of OsEILs in wounded rice and the DNA binding characteristics of proteins encoded by wound-inducible OsEIL1 and 2.[OsEIL1, OsEIL2] (Mus musculus) PubMed
5639.
OsRPA1a plays an essential role in DNA repair but may not participate in, or at least is dispensable for, DNA replication and homologous recombination in rice.[OsRPA1a] (Mus musculus) PubMed
5640.
The effects of polymorphisms of the T cell receptor beta chain on body weight and fecal oocyst shedding during coccidiosis shedding are reported.[TCR-beta] (Mus musculus) PubMed
5641.
50 methicillin resistant Staphylococcus aureus all have the same mecA genotype. [mecA] (Mus musculus) PubMed
5642.
PNG1 ortholog from the filamentous ascomycete Neurospora crassa is an essential protein, and its deletion results in strong polarity defects[PNG1] (Mus musculus) PubMed
results illustrate a cellular response to environmental and genetic perturbations through remodeling of the Skp1-Cullin-F-box protein complex-mediated ubiquitination system.[Cullin and Skp1] (Mus musculus) PubMed
5645.
The first crystal structure at 1.0 and 1.7 A resolution of two recombinant Schistosoma mansoni glutathione peroxidases, carrying the active site mutations Sec43Cys and Sec43Ser, respectively.[Gpx4] (Mus musculus) PubMed
5646.
auto-induction of murR by an activated form of MurR (Mus musculus) PubMed
5647.
inter-spin distances suggest that the transmembrane helices of TatA subunits are arranged as a single-walled ring containing a contact interface between Ile(12) on one subunit and Val(14) on an adjacent subunit[TWIN ARGININE PROTEIN TRANSLOCASE] (Mus musculus) PubMed
5648.
provided the first evidence for the temporal production and utilization of four different bovine foamy virus (BFV) btas mRNAs during persistent infection. [btas] (Mus musculus) PubMed
5649.
Study solved at 2.6 A resolution the 3D structure of the TonB-dependent heme/hemoglobin outer membrane receptor ShuA from S. dysenteriae; ShuA binds to hemoglobin and transports heme across the outer membrane. [ShuA] (Mus musculus) PubMed
5650.
Overepression of A. fumigatus AfCrzA increased the mRNA accumulation of several genes. AfRcnA affects the mRNA accumulation of genes whose expression is influenced by AfcrzA. [CrzA; RcnA] (Mus musculus) PubMed
5651.
The authors identified a new cathepsin L termed SmCL3 using PCR strategies based on S. mansoni EST sequence data.[CL3] (Mus musculus) PubMed
5652.
Comparative analyses of the genetic diversity between the PRRSV isolate HH08 and other Chinese as well as foreign reference strains of PRRSV were discussed based on the sequence comparison and the topology of phylogenetic trees constructed[HH08] (Mus musculus) PubMed
5653.
Data provide evidence for neural control of tick salivary gland by myoinhibitory peptide MIP and SIFamide from the synganglion.[myoinhibitory peptide (MIP)] [SIFamide] (Mus musculus) PubMed
5654.
UDG efficiently removes uracil from internal locations in the nucleosome where the DNA backbone is oriented away from the surface of the histone octamer, without significant disruption of histone-DNA interactions[UDG] (Mus musculus) PubMed
5655.
Report a metabolic pattern in ciona intestinalis consistent with the presence of an As3mt ortholog in its genome and constitutive expression of the gene in prominent organs. (Mus musculus) PubMed
5656.
The current study reveals that in the Lister427 strain of T. brucei, a gene conversion replaced the coding region for the GAF-A domain of TbrPDEB2 by the corresponding region of the upstream gene TbrPDEB1.[PDEB1 & PDEBE2] (Mus musculus) PubMed
5657.
Study identified the zfh2 gene as a novel factor required for normal leg development in Tribolium. (Mus musculus) PubMed
5658.
Purification of 84kDa protein/Surface expression was detected in intermediate forms between trypomastigotes and amastigotes/ the gene starts expressing when trypomastigotes begin transformation into amastigotes [SSP4/amastigote-specific surface protein] (Mus musculus) PubMed
5659.
Urotensin-II increased resting papillary muscle length. This effect was increased in the presence of angiotensin-II, but was unaffected by the presence of endothelin-1. [Urotensin-II] (Mus musculus) PubMed
5660.
a 42kDa protein was purified from retina and was a biotin-coupled bifunctional enzyme containing glutamine synthetase activity and glutamate decarboxylase activity. Biotin was possibly involved in activities. [p42/42kDa biotin-coupled protein] (Mus musculus) PubMed
5661.
PhlA is a hemolysin that induces destabilization of target cell membranes in the presence of phospholipids. [PhlA] (Mus musculus) PubMed
5662.
Identification of a bacterial GatCAB-specific element that enables this enzyme to distinguish a U1-A72 base pair from a G1-C72 pair (GatC, GatA and GatB). (Mus musculus) PubMed
5663.
It regulates reactive oxygen species mediated by proline metabolism and protects Saccharomyces cerevisiae from oxidative stress. (review) (Mus musculus) PubMed
5664.
The crystal structure of TbATG8B, is presented.[ATG8] (Mus musculus) PubMed
5665.
TNFR encodes a complete receptor sequence composed of 599 amino acids, and contains four cysteine-rich domains. [TNFR] (Mus musculus) PubMed
5666.
HIM-18, an ortholog of MUS312/Slx4, is identified as a critical player required in vivo for processing late homologous recombination intermediates in Caenorhabditis elegans.[HIM-18, SLX-1, XPF-1] (Mus musculus) PubMed
5667.
The authors conclude that COT1 regulates elongation and branching in an independent manner, which is determined by its phosphorylation state.[COT1] (Mus musculus) PubMed
5668.
Computational solvent mapping of both x-ray and NMR structures of the influenza M2 proton channel shows the most important binding hot spot inside the pore, surrounded by the amino acid residues Ala30, Ser31, and Gly34 [M2] (Mus musculus) PubMed
5669.
Together, the data demonstrate that the p32, p39 and p30 proteins of FCV locate to the ER and lead to reorganization of ER membranes.[p39] (Mus musculus) PubMed
5670.
An isogenic mutant strain defective in AtlA expression exhibited reduced survival and virulence when tested in a rat model of infective endocarditis compared with the wild-type and complemented strains.[AtlA] (Mus musculus) PubMed
5671.
Different Pol IV isoforms play distinct roles in the maintenance of meiotically-heritable epigenetic information in the grasses.[NRPD1, NRPD2] (Mus musculus) PubMed
5672.
Parasites with one intact GSH1 chromosomal allele lost the rescuing plasmid but not the double knockout, when grown in the absence of antibiotic, indicating the essentiality of the GSH1 gene in Leishmania.[GSH1] (Mus musculus) PubMed
5673.
CspA mRNA is able to sense temperature downshifts, adopting functionally distinct structures at different temperatures without the aid of trans-acting factors. (Mus musculus) PubMed
5674.
PhoB acts to diminish biofilm formation by lowering the expression of the positive regulator VpsR and modulates resistance to environmental stresses in a manner independent of RpoS. [phoB/VpsR/Vibrio cholerae El Tor C7258] (Mus musculus) PubMed
5675.
ferredoxin is involved in secretion of CNF1 across the inner membrane in meningitis-causing E. coli K1 [CNF1} (Mus musculus) PubMed
5676.
The expression of the AOX, well-tolerated by the cells, compensates for both the growth defect and the pronounced oxidant-sensitivity of COX-deficient human cells.[AOX] (Mus musculus) PubMed
5677.
candida aspartate semialdehyde dehydrogenase (ASADH) is a functional dimer, with a similar overall fold and domain organization to the structurally characterized bacterial ASADHs.[aspartate beta-semialdehyde dehydrogenase] (Mus musculus) PubMed
5678.
MOSAIC FLORAL ORGANS1 (MFO1/MADS6) regulates floral organ identity and floral meristem determinacy. [MFO1] (Mus musculus) PubMed
5679.
MinC and MinD proteins, but not MinE, influence Bacillus subtilis cell division. Expression of these heterologous Min proteins resulted in cell elongation. [MinC/MinD/MinE/Escherichia coli strain MM294] (Mus musculus) PubMed
5680.
DeltaIE1 had a diminished ability to infect salivary glands persistently in vivo and to reactivate from spleen explant cultures ex vivo.[IE1] (Mus musculus) PubMed
5681.
a novel enterocin with bactericidal mode of action (Mus musculus) PubMed
5682.
Results describe the subcellular localization and the oligomeric organization of Vipp1 from Synechocystis PCC 6803, and show that Vipp1 forms stable dimers and higher-ordered oligomers in the cytoplasm and at cytoplasmic and thylakoid membranes. (Mus musculus) PubMed
5683.
C. elegans ATAD-3 is essential for mitochondrial activity and development [ATAD-3, also called F54B3.3] (Mus musculus) PubMed
5684.
gamma-Glutamylcysteine synthetase from Escherichia coli has the ability to combine Glu and amines to form gamma-glutamylamides.[gamma-glutamylcysteine synthetase] (Mus musculus) PubMed
5685.
YggT endowed E. coli cells with a tolerance for osmotic shock. [YggT] (Mus musculus) PubMed
5686.
Ecl1 family proteins are novel regulatory factors involved in chronological lifespan among yeasts.[Ecl1] (Mus musculus) PubMed
5687.
Direct Repeat 6 from human herpesvirus-6B encodes a nuclear protein that forms a complex with the viral DNA processivity factor p41 [gp41] (Mus musculus) PubMed
5688.
Identification of the protease responsible for Plasmodium protein export into erythrocytes [plasmepsin V] (Mus musculus) PubMed
5689.
A deletion in lrhA reduced the transcription levels of pchA and pchB to different degrees, and also reduced the expression of locus of enterocyte effacement -coded type 3-secreted protein, EspB.[PchA & PchB] (Mus musculus) PubMed
5690.
Study identified 31 distinct proteins in the secretome of wild-type C. glabrata cells by MS/MS of proteins-most of these proteins are predicted to be cell wall proteins, cell wall modifying enzymes and aspartyl proteinases.[Ace2] (Mus musculus) PubMed
5691.
function of mitochondrial Adh3 in the thermotolerant yeast Kluyveromyces marxianus [Adh3] (Mus musculus) PubMed
5692.
The expression of CDR1 in rice and transgenic Arabidopsis thaliana in response to plant disease signals is reported.[CDR1] (Mus musculus) PubMed
5693.
Using a chemical genetic approach the authors demonstrate that the germinal centre kinase Don3 triggers this septin reorganization during secondary septum formation.[Don3] (Mus musculus) PubMed
5694.
plasmepsin V, an ER aspartic protease with distant homology to the mammalian processing enzyme BACE, recognizes the PEXEL motif and cleaves it at the correct site [plasmepsin V] (Mus musculus) PubMed
5695.
The gene product catalyzed the oxidation of formate to yield hydrogen peroxide but showed no evidence of activity on the other substrates tested. [formate oxidase] (Mus musculus) PubMed
5696.
Comparative analyses of fungal strains infected by wild-type Mycoreovirus 1 and its variants carrying rearrangements of S4 showed that S4 is non-essential for virus replication but required for efficient vertical transmission and symptom expression.[S4] (Mus musculus) PubMed
5697.
we identified a 52 kDa human antigen/it is a modestly glycosylated mature protein with a pI 5.3/ identical to a glucoamylase previously reported from an aluminum-tolerant P. chrysogenum mutant. [glucoamylase/Penicillium chrysogenum-MEA] (Mus musculus) PubMed
5698.
Covalently attached penicillins press against a phenylalanine residue near the active site and disturb the deacylation step.[PBP4 & PBP5] (Mus musculus) PubMed
5699.
Together, these findings indicate that Xanthomonas campestris CLP regulates bacterial virulence gene expression in a manner negatively controlled by the c-di-GMP concentrations.[CLP] (Mus musculus) PubMed
5700.
The authors demonstrate that SarA is capable of binding DNA with high affinity but that its binding affinity and pattern of shifted complexes in electrophoretic mobility shift assays is responsive to the redox state.[SarA] (Mus musculus) PubMed
5701.
Ace is involved in pathogenesis of, and is useful for protection against, E. faecalis experimental endocarditis (Mus musculus) PubMed
5702.
Lysozyme c-1 plays an important role in antibacterial defense against selected bacteria. [LYSC-1] (Mus musculus) PubMed
5703.
the splicesosome machinery for trout cyp19b1 that includes intronic sequence and edits presumptive exon 2 to generate transcripts with 5'-UTRs of a variety of lengths [cyp19b1] (Mus musculus) PubMed
5704.
Over-expression of wheat TaDi19A in Arabidopsis increased the plants' sensitivity to salinity stress, ABA and mannitol during the germination stage. [TaDil9A] (Mus musculus) PubMed
5705.
Embp is a multifunctional cell surface protein that mediates attachment to host extracellular matrix, biofilm accumulation and escape from phagocytosis, and therefore is well suited for promoting implant-associated infections.[Embp] (Mus musculus) PubMed
5706.
The authors conclude that the status of sspBC in S. aureus, as paralogues of the ancestral scpAB genes, facilitated a different activation mechanism, a stable proSspB isoform and modified Staphostatin function.[SspB & SspC] (Mus musculus) PubMed
5707.
The bE1/bW1 complex is required and sufficient to initiate pathogenic development and sexual reproduction.[bE1 and bW1] (Mus musculus) PubMed
5708.
Synthetic lethal interactions between members of the cohesin complex and CTF4, RAD27, and components of the alternative RFC(CTF18) complex.[CTF18] (Mus musculus) PubMed
5709.
study concludes ORFV125's mechanism of action is Bcl-2-like and propose that the viral protein's combined ability to bind to a range of BH3-only proteins as well as the active form of Bax provides significant protection against apoptosis [ORFV125] (Mus musculus) PubMed
5710.
RecF, recO and recR proteins are essential for DNA double-strand-break repair. [recO] (Mus musculus) PubMed
5711.
data suggest that Zn(2+)-Atx1 can form in vivo [Atx1] (Mus musculus) PubMed
5712.
Data show that p24 delta2 and alpha3 furnish subcompartments of the secretory pathway with specific sets of machinery cargo to provide the proper microenvironments for efficient and correct secretory protein transport and processing [p24alpha3, delta2]. (Mus musculus) PubMed
5713.
Visualization of surface potentials around the substrate-binding region of the enzymes have demonstrated a more positive potential for Aliivibrio salmonicida uracil-DNA N-glycosylase(asUNG) compared with Vibrio cholerae UNG.[uracil-DNA N-glycosylase] (Mus musculus) PubMed
5714.
native crystals of RspB diffracted to a resolution of 2.5 A using an in-house X-ray source, while the selenomethionine-derivative crystals diffracted to a resolution of 2.2 A using synchrotron radiation. [RspB] (Mus musculus) PubMed
5715.
DEP and AFO are both required to ensure sexual reproduction in rice. [DEP,AFO] (Mus musculus) PubMed
5716.
findings show that the transcriptional regulator VpsT directly senses cyclic di-guanosine monophosphate to inversely control extracellular matrix production and motility, which identifies VpsT as a master regulator for biofilm formation [VpsT] (Mus musculus) PubMed
5717.
Although ORF50 protein does not directly bind to the ORF61 and ORF60 promoters in vitro, the authors show the association of ORF50 protein with these two promoters in vivo.[ORF61, ORF60, ORF50] (Mus musculus) PubMed
5718.
Both the dimeric and folded monomeric forms of HIV-2 protease were characterized by solution NMR and compared with HIV-1 protease.[HIV-2 protease] (Mus musculus) PubMed
5719.
OsIRL may behave as an antioxidant in response to oxidative stresses in suspension-cultured cells as well as during root development in rice. [OsIRL] (Mus musculus) PubMed
5720.
CovS mutation uniformly repressed capsule expression and hampered keratinocyte adherence in all serotypes. [CovS] (Mus musculus) PubMed
5721.
Functional studies and modeling of pore-lining residue mutants of the influenza a virus M2 ion channel (Mus musculus) PubMed
5722.
BAFF and its receptors during B-cell activation and autoantibody production in rabbits derived from selective breeding to develop a reproducible rabbit model of Systemic Lupus Erythematosus, were investigated.[BR3, TACI] (Mus musculus) PubMed
5723.
While NPR1 has a positive effect on pathogen resistance, it has a negative effect on symbiotic interactions, by inhibiting root hair deformation and nodulin expression.[NPR1] (Mus musculus) PubMed
5724.
SigA binds to epithelial HEp-2 cells as well as being able to induce fodrin degradation in vitro and in situ, further extending its documented role in the pathogenesis of Shigella infections.[SigA] (Mus musculus) PubMed
5725.
Structural and functional studies of Aspergillus clavatus N(5)-carboxyaminoimidazole ribonucleotide synthetase (Mus musculus) PubMed
5726.
these data thus suggest that the PRMT1 plays a key role as a cellular regulator of HSV-1 replication through ICP27 RGG-box methylation.(ICP27) (Mus musculus) PubMed
5727.
identified a JmjC domain protein in Neurospora, DNA METHYLATION MODULATOR-1 (DMM-1), that prevents aberrant spreading of DNA and histone H3K9 methylation from inactivated transposons into nearby genes [DMM-1] (Mus musculus) PubMed
5728.
L alpha-glucan phosphorylase has higher catalytic efficiency toward both linear and branched alpha-glucans in the synthesis direction than in the degradation direction.[L alpha-glucan phosphorylase] (Mus musculus) PubMed
5729.
findings show that translocation and phosphorylation of CagA are necessary, but not sufficient, for the induction of hummingbird phenotype in AGS cells infected with Helicobacter pylori [CagA] (Mus musculus) PubMed
5730.
The cloning and characterization of Francisella tularensis MEP synthase, a MEP pathway enzyme and potential target for antibiotic development, is described.[MEP synthase] (Mus musculus) PubMed
5731.
In addition to its localization in the cytoplasm and in the nucleoid, a significant amount of Hfq protein is located at the cell periphery.[Hfq] (Mus musculus) PubMed
5732.
Mapping of the signal peptide-binding domain of Escherichia coli SecA using Forster resonance energy transfer. (Mus musculus) PubMed
5733.
identified DNF1 gene encoding a subunit of a signal peptidase complex highly expressed in nodules; propose symbiosome development requires secretion of proteins through coordinated upregulation of a nodule-specific pathway exemplified by DNF1[DNF1] (Mus musculus) PubMed
5734.
We conclude that Erm dependence functionally distinguishes intermediate neural progenitors from neuroblasts in the Drosophila larval brain, balancing neurogenesis with stem cell maintenance.(EARMUFF PROTEIN, DROSOPHILA) (Mus musculus) PubMed
5735.
Deletion of one mgt1 allele from L. major led to increased virulence, while deletion of one allele of mgt2 resulted in slower growth and total loss of virulence in vitro and in vivo.[MGT1, MGT2] (Mus musculus) PubMed
5736.
The authors show that bromodomain factor 2 (BDF2), is expressed in discrete regions inside the nucleus of all the parasite life cycle stages and binds H4 and H2A purified histones from Trypanosoma cruzi.[BDF2] (Mus musculus) PubMed
5737.
DR0093 was confirmed to encode gamma-carotene ketolase to catalyse the ketolation of g-carotene derivatives in the native host. [DR0093/Deinococcus radiodurans strain R1] (Mus musculus) PubMed
5738.
the collagen-binding protein SdrI of S. saprophyticus, a member of the Sdr-family, can also bind fibronectin.[SdrI/Staphylococcus saprophyticus strain 7108] (Mus musculus) PubMed
5739.
The authors observed that substitution of both chromosomal TXN1 alleles was only possible upon parasite complementation with an episomal copy of the gene indicating the essentiality of TXN1.[TXN1] (Mus musculus) PubMed
5740.
Results describe the subcellular localization of ICP27 and its colocalization with cellular RNA export factors Aly/REF and TAP/NXF1. (Mus musculus) PubMed
5741.
Proposed is that the peptide region 207-216 is a flexible loop and that H208, Y211, R212 and Q214 of this loop are involved in the correct assembly of the DNA-integrase complex during integration.[Integrase] (Mus musculus) PubMed
5742.
Vrn-D4, which was mapped within a 1.8 cM interval flanked by markers Xcfd78 and Xbarc205 in the centromeric region of chromosome 5D.[Vrn-D4] (Mus musculus) PubMed
5743.
the Ile(13) residue of microcin J25's tetrapeptide sequence (VGIG) is only required for interaction with FhuA, and VGIG is not a major recognition element by SbmA. [FhuA/SbmA/Escherichia coli AB1133] (Mus musculus) PubMed
5744.
Hypophosphorylation of VSV P protein was found to occur in neuronal cell lysates, but not within budded virions from the same IFN-beta-treated cells. phosphoprotein P. (Mus musculus) PubMed
5745.
These data suggest that Soa proteins are components of a molecular mechanism controlling lipase gene expression in response to extracellular triacylglycerol.[SOA1, SOA2] (Mus musculus) PubMed
5746.
The fission yeast Schizosaccharomyces pombe Ssp1 kinase, which controls G2/M transition and response to stress, is the putative CaMKK. (Mus musculus) PubMed
5747.
irvA promotes Dextran-dependent aggregation not only by GbpC, a cell surface glucan-binding protein, but also via an increase in the major surface adhesin P1 [irvA] (Mus musculus) PubMed
5748.
NS3h translocates on ssDNA as a monomer, but the translocase activity does not correspond to comparable DNA unwinding activity or protein displacement activity under identical conditions.[NS3] (Mus musculus) PubMed
5749.
A tau class GST gene (OsGSTU17) was cloned from rice, which encodes a protein of 223 amino acid residues with a calculated molecular mass of 25.18 kDa. The recombinant OsGSTU17 formed a homodimer protein and showed GSH-conjugating activity...[OsGSTU17] (Mus musculus) PubMed
5750.
The assembly of F(1)F(O)-ATP synthase is disrupted upon interference of RNA editing in Trypanosoma brucei. [F(1)F(O)-ATP synthase] (Mus musculus) PubMed
5751.
Prohibitin 1 (PHB1) and 2 (PHB2) appear to be indispensable for mitchondrial translation.[PHB1, PHB2] (Mus musculus) PubMed
5752.
Identified MtMTP1, a Zn transporter of the CDF family in the legume model plant Medicago truncatula. [MtMTP1] (Mus musculus) PubMed
5753.
In yeast, the secretion of SDF-2-like activity is GRASP dependent, triggered by nitrogen starvation, and requires autophagy proteins as well as medium-chain fatty acyl CoA generated by peroxisomes.[Acb1] (Mus musculus) PubMed
5754.
These findings suggest that FAM3C is involved in retinal laminar formation processes in vertebrates.(XFAM3C) (Mus musculus) PubMed
5755.
The temperature sensitivity of the photoreaction of YcgF suggests that this protein could have a biological function as a temperature sensor as well as behaving as a light sensor [YcgF] (Mus musculus) PubMed
5756.
the solution structure of the norsolorinic acid synthase (NSAS) holo ACP domain of type I polyketide synthase [type I polyketide synthase] (Mus musculus) PubMed
5757.
crystals of the reduced enzyme and of the enzyme in complex with a wide range of ligands typically led to high-quality complete data sets to 1.30-1.60 A resolution[SYE4] (Mus musculus) PubMed
5758.
Crystals were obtained in space group P4(1)2(1)2 and diffracted to 2.0 A resolution, with unit-cell parameters a = b = 89.4, c = 179.6 A.[diaminopimelate epimerase] (Mus musculus) PubMed
5759.
data indicate that LpxC can use either Fe(2+) or Zn(2+) to activate catalysis in vitro and possibly in vivo, which may allow LpxC to function in E. coli grown under different environmental conditions [LpxC] (Mus musculus) PubMed
5760.
Genetic analysis revealed hybrid breakdown involving weakness phenotype in the F2 progenies to be controlled by two recessive genes: hybrid breakdown 2 (hbd2) and hbd3.[hbd2 and hbd3] (Mus musculus) PubMed
5761.
the crystals were thought to belong to space group P4(2)2(1)2, with unit-cell parameters a = 105.5, b = 105.5, c = 62.4 A. However, the R factors remained high following initial processing of the data[dihydrodipicolinate synthase (S pneumoniae OXC141)] (Mus musculus) PubMed
5762.
Data imply that a SUMO system essential for regulating cell cycle progression might exist in the procyclic-form T. brucei [SUMO]. (Mus musculus) PubMed
5763.
Expb1 are needed for pollen separation and stigma penetration. [Expb1] (Mus musculus) PubMed
5764.
Membrane targeting by RSBP-1 is essential for EAT-16 activity.[RSBP-1, EGL-10] (Mus musculus) PubMed
5765.
The authors conclude that H. pylori HspA is involved in intracellular nickel sequestration and detoxification and plays a novel role as a specialized nickel chaperone involved in nickel-dependent maturation of hydrogenase.[HspA] (Mus musculus) PubMed
5766.
Together, these data support the hypotheses that BinA functions as a phosphodiesterase and that c-di-GMP activates cellulose biosynthesis.[BinA] (Mus musculus) PubMed
5767.
DSM1 may act as an early signal regulating the responses to drought stress in rice. Drought hypersensitivity of dsm1 is partially due to a decrease in reactive oxygen species scavenging. [DSM1] (Mus musculus) PubMed
5768.
Hd6 requires functional Hd1 for flowering repression under long day conditions, and does not affect circadian rhythms. (Mus musculus) PubMed
5769.
study evaluated the role of Cwt1p in morphogenesis, cell wall architecture & virulence; findings suggest that an intermediate dosage of Cwt1 affects phenotypes profoundly, while its complete absence may elicit compensatory responses of C. albicans [Cwt1] (Mus musculus) PubMed
5770.
Antisense MtSucS1 sucrose synthase provoked an impaired arbuscular mycorrhiza fungal colonization, and plants had reduced growth and reproduction, photosynthetic activity, and an impaired nutritional status. [SucS1] (Mus musculus) PubMed
5771.
Phosphoenolpyruvate carboxylase binds phosphatidic acid and its activity is inhibited by anionic phospholipids. [PepC] (Mus musculus) PubMed
5772.
Stp1 is a functionally conserved orthologue of the mammalian Site-2 protease and Stp1 cleaves Sre1 within its predicted first transmembrane segment (Stp1). (Mus musculus) PubMed
5773.
These data demonstrate a role of the E3 ubiquitin ligases in CTA1 retro-translocation.[CTA1] (Mus musculus) PubMed
5774.
ModE of C. jejuni differentially regulates both molybdenum and tungsten transport (ModE). (Mus musculus) PubMed
5775.
Dissection of the opposing synthetic and hydrolytic functions of trypanothione synthetase-amidase (TRYS) in order to independently study their respective roles in T. brucei cell virulence and viability (TRYS). (Mus musculus) PubMed
5776.
characterization of PTK2 role in turgor regulation; osmoadaptation role is unrelated to activity of MAP kinase cascade; it acts in an alternative pathway that, like the MAP kinase cascade, also involves ion transport mediated osmoadaptation [Ptk2] (Mus musculus) PubMed
5777.
Identified is a new icd gene encoding isocitrate dehydrogenase from Helicobacter pylori.[isocitrate dehydrogenase] (Mus musculus) PubMed
5778.
Compared are the enzyme kinetics of alpha-glucosidase from Saccharomyces cerevisiae during denaturation by guanidinium chloride and SDS.[alpha-glucosidase] (Mus musculus) PubMed
5779.
Comparison of eIF4G(tsv1) gene sequences among susceptible and resistant plants suggested the association of RTSV resistance with one of the single nucleotide polymorphism sites found in exon 9 of the gene [eIF4G, translation initiation factor] (Mus musculus) PubMed
5780.
Erl1 and Gin-N are orthologs and might be involved in the control of hyphal growth in planta [erl1] (Mus musculus) PubMed
These data suggest that TolC function is required for Francisella tularensis to inhibit host cell death and dampen host immune responses. (Mus musculus) PubMed
5783.
AatA was shown to enhance adhesion of avian pathogenic Escherichia coli to chicken embryo fibroblast cells and to contribute to APEC virulence.[AatA] (Mus musculus) PubMed
5784.
crystal structure of an E. coli AdiC variant bound to Arg at 3.0 A resolution [AdiC] (Mus musculus) PubMed
5785.
gene was found to exist in most pathogenic strains but scarcely in non-invasive isolates[Streptococcus suis, strain 05ZYS ; IgA1 protease] (Mus musculus) PubMed
5786.
In this study, 16 20-mer-long synthetic peptides spanning the entire ribosomal phosphoprotein sequence were evaluated by means of receptor-ligand assays with human red blood cells. (Mus musculus) PubMed
5787.
evidence that PfUCHL3 is essential to parasite survival [UCHL3] (Mus musculus) PubMed
5788.
study concluded that atfA is involved in conidial germination via carbon and nitrogen source metabolism [atfA] (Mus musculus) PubMed
5789.
WRN-1 functions together with RPA-1 upstream of ATM and ATR to trigger cell cycle arrest in response to double-strand DNA breaks. [ATR] (Mus musculus) PubMed
5790.
Rrp36p protein is nucleolar and interacts with 90S and pre-40S preribosomal particles. Its depletion affects early cleavages of the 35S pre-rRNA and results in a rapid decrease in mature 18S rRNA levels. (Rrp36p) (Mus musculus) PubMed
5791.
Fbl and ClfA bind the same site in fibrinogen by similar mechanisms [Fbl] (Mus musculus) PubMed
5792.
A H145Y mutation in metK is responsible for a 70% decrease in intracellular S-adenosylmethionine content which probably affects the activities of numerous SAM-dependent enzymes.[metK] (Mus musculus) PubMed
5793.
This effect of AgC10 is likely due to its ability to induce L-selectin shedding from the monocyte membrane, since pharmacologic blocking of this shedding prevents AgC10 activity. (Mus musculus) PubMed
5794.
These results indicate that OsACDR1 plays an important role in the positive regulation of disease resistance in rice.[OsACDR1] (Mus musculus) PubMed
5795.
We cloned the EP2 gene by way of a map-based cloning strategy. (Mus musculus) PubMed
5796.
ORF19 knock down by RNA interference inhibited virus replication indicating that the gene is indispensable for HvAV-3e replication.[ORF19] (Mus musculus) PubMed
5797.
uhpA involved in regulating sulfur assimilation pathways upon up-shift high osmotic treatment for 30 min [UhpA] (Mus musculus) PubMed
5798.
a dense granule protein that displays no homology with other proteins/ behaves similarly to both GRA2 and GRA6/ may bind non-specifically to the moving junction complex in vitro. [GRA12] (Mus musculus) PubMed
5799.
Structural perturbation results from a buried thiolate anion attributed to suppression of the Cys sulfhydryl group pK(a) from 9.4 in aqueous solvent to 7.5 in the hydrocarbon ruler microenvironment. [PagP] (Mus musculus) PubMed
5800.
The results suggest that the physiological role of beta-N-acetylglucosaminidase is to degrade the chitooligosaccharides transported through membrane following hydrolysis of chitin into beta-N-acetylglucosamine (beta-N-acetylglucosaminidase). (Mus musculus) PubMed
These results raise the possibility that loss of OsUBP6 is functionally compensated for by an as-yet unknown OsUBP homolog during later stages of development in rice plants.[OsUBP6] (Mus musculus) PubMed
5803.
Metformin attenuated the progression of aortic atherosclerosis via down-regulation of nuclear NF-kappaB subunit p65 (RelA). (Mus musculus) PubMed
5804.
Results show that REL2 is crucial for A. aegypti immunity upon infection with Escherichia coli and Bacillus subtilis.[REL2] (Mus musculus) PubMed
5805.
The results suggest that the physiological role of beta-N-acetylglucosaminidase (cbsA)is to degrade the chitooligosaccharides transported through membrane following hydrolysis of chitin into beta-N-acetylglucosamine (cbsA). (Mus musculus) PubMed
5806.
The effect of suppressing the lepB protein on twin-arginine signal peptide metabolism is reported.[lepB] (Mus musculus) PubMed
5807.
The half-life of p130, relative to control cells, was decreased in the cytoplasm in the presence of human papillomavirus 6 E7 or human papillomavirus 16 E7, but only decreased by HPV 6 E7 in the nucleus. (Mus musculus) PubMed
5808.
A recent study now shows that two additional tyrosines within Tir recruit the inositol phosphatase SHIP2 to generate a PI(3,4)P2-enriched membrane platform that stabilizes pedestal assembly.[Tir] (Mus musculus) PubMed
5809.
Together, this study suggests that BFV activates the NF-kappaB pathway through BTas to enhance viral transcription.[BTas] (Mus musculus) PubMed
5810.
the activation mechanism of botulinum neurotoxin type E upon nicking and subsequent reduction of disulfide bond (Mus musculus) PubMed
5811.
Orysa;CycB1;1 expression is critical for endosperm formation via the regulation of mitotic division, and the endosperm plays an important role in maintenance of embryo development in rice.[Orysa;CycB1;1] (Mus musculus) PubMed
5812.
LAP was optimally active at slightly alkaline pH and its activity was dependent on divalent metal ions. [Lap] (Mus musculus) PubMed
5813.
TgLAP is a functional aminopeptidase in the cytoplasm. (Mus musculus) PubMed
5814.
PfRh5 binds to glycosylated receptors on erythrocyte surface/localises to rhoptries in merozoites and follows the tight junction during the process of erythrocyte invasion/may play a key role in invasion. [Reticulocyte-binding protein homologue 5/PfRh5] (Mus musculus) PubMed
Deletion of amino acids 3-11 of NikR abolished the nickel-responsive activity and enhanced nonspecific DNA binding. [NikR] (Mus musculus) PubMed
5817.
AP180 interacts with the cytoplasmic domain of Vamp7B & directs it into clathrin-coated vesicles on contractile vacuoles, regulating the internal distribution of fusion-competent SNARE proteins & limiting homotypic fusions among contractile vacuoles. (Mus musculus) PubMed
5818.
CP250, a 2110-AA corona component, is an acidic coiled-coil protein present throughout interphase, disappearing during prophase & reappearing at late telophase. AAs 756-1148 are enough for centrosomal targeting & cell-cycle-dependent association. (Mus musculus) PubMed
5819.
Results of this study support the active role of rpoS in the low salinity adaptation of Vibrio vulnificus by regulating the expression of virulence and low salinity-associated factors[RpoS] (Mus musculus) PubMed
5820.
The study reports that substitution of the acidic surface residue Glu226 to Ala in ascorbate peroxidase from Leishmania major alters the 5 coordinate high spin (5cHS) to a 6 coordinate low spin (6cLS) form at pH 7.5.[ascorbate peroxidase] (Mus musculus) PubMed
5821.
These findings support acceleration of gp41-induced membrane fusion by early pre-hairpin intermediate conformation and fusion arrest after folding to the final six-helix bundle structure.[gp41] (Mus musculus) PubMed
5822.
The Erect Panicle 3 (EP3) gene has been mapped and cloned. (Mus musculus) PubMed
5823.
evidence is provided for the function of the periplasmic fumarate reductase FccA and the decaheme c-type cytochrome MtrA in periplasmic electron transfer reactions in the gammaproteobacterium Shewanella oneidensis.[FccA] (Mus musculus) PubMed
5824.
The X-ray crystal structure of CmlS determined at 2.2 A resolution, is determined.[CmlS] (Mus musculus) PubMed
5825.
The heterotrimeric G-protein alpha subunit protein RGA1 participates in the regulation of cell number in a developmental stage-dependent manner. [RGA1] (Mus musculus) PubMed
5826.
The authors demonstrated that Aur and SspA, two proteases that are overexpressed in the sigB mutant strain and are capable of degrading Bap, inhibit biofilm formation.[Bap & SspA & Aur] (Mus musculus) PubMed
5827.
FRH is a core component of the central oscillator that is permissive for rhythmicity but appears not to modulate periodicity. (Mus musculus) PubMed
5828.
uncovers the strategy used by the photosynthetic alpha-proteobacterium Rhodobacter sphaeroides to procure the cobamide it needs to grow on acetate as a carbon and energy source requires CbiZ enzyme. [CbiZ] (Mus musculus) PubMed
5829.
14-3-3 post-translational modifications act in combination to affect encystation in Giardia duodenalis. [14-3-3] (Mus musculus) PubMed
5830.
Genetic analysis confirmed that rdxA and rdxB are cotranscribed and induced during in vivo growth in the chick intestinal tract, but an absence of these genes did not strongly impair C. jejuni for commensal colonization.[RdxB] (Mus musculus) PubMed
5831.
the effect of the single-residue mutation of leucine 42 to arginine (L42R) centrally positioned in the polypeptide binding pocket of SecB on its chaperonin function [SecB] (Mus musculus) PubMed
5832.
The authors created an hdrR overexpression strain and showed that it could reproduce each of the hdrM competence and mutacin phenotypes, indicating that HdrM acts as a negative regulator of HdrR activity.[hdrR & hdrM] (Mus musculus) PubMed
5833.
Data suggest that the ICP27-independent gC expression occurred even in the absence of viral DNA synthesis, indicating that the silencing element helps to regulate the tight DNA replication-dependent expression of gC [ISP27]. (Mus musculus) PubMed
5834.
The data confirm that covS plays a direct role in regulating Group A Streptococcus virulence[covS] (Mus musculus) PubMed
5835.
Although ORFV024 interferes with activation of the NF-kappaB signaling pathway, its deletion from the OV-IA82 genome had no significant effect on disease severity, progression, and time to resolution in sheep.[ORFV024] (Mus musculus) PubMed
5836.
PAKB pathway is central to eliciting the appropriate morphogenetic response by the pathogen to the host environment independently of the common temperature signal, thus separating the temperature- and intracellular-dependent signaling systems[PAKB] (Mus musculus) PubMed
5837.
X-ray diffraction data to 1.85 A resolution were collected from a monoclinic crystal of 1-deoxy-D-xylulose 5-phosphate reductoisomerase. [1-deoxy-D-xylulose 5-phosphate reductoisomerase] (Mus musculus) PubMed
5838.
X-ray diffraction data of phosphoglucose isomerase to 1.5 A resolution were collected from an orthorhombic crystal form belonging to space group P2(1)2(1)2(1) with unit-cell parameters a = 103.3, b = 104.1, c = 114.6 A.[phosphoglucose isomerase] (Mus musculus) PubMed
5839.
Here, the authors show that self-protection is provided by the pneumococcal LiaFSR system, which senses the damage inflicted to the cell wall by CbpD, LytA, and LytC.[LiaF, LiaS & LiaR] (Mus musculus) PubMed
5840.
A Trypanosoma brucei DNA primase gene, PRI1, that encodes a 70-kDa protein that localizes to the kinetoplast and is essential for both cell growth and kinetoplast DNA replication, is described.[PRI1] (Mus musculus) PubMed
5841.
X-ray diffraction data of alternative oxidase were collected at 100 K and were processed to 2.9 A resolution with 93.1% completeness and an overall R(merge) of 9.5%.[cyanide-insensitive alternative oxidase] (Mus musculus) PubMed
5842.
This is the first study to demonstrate the roles of antisera against sortase A (SrtA) and lipase 2 in the inhibition of biofilm formation in S. aureus.[SrtA; lipase2] (Mus musculus) PubMed
5843.
Xenopus Wnt11b is identified as a potential pronephric inducer. [Wnt11b] (Mus musculus) PubMed
5844.
DadA with 44 kDa molecular mass possessed FAD as cofactor, and showed the highest activity to D-proline. [DadA] (Mus musculus) PubMed
5845.
fetal cortisol concentrations are suppressed by adenosine A(1) receptor activity, largely though a direct adrenal mechanism[ADENOSINE A1 RECEPTOR] (Mus musculus) PubMed
5846.
The IE62 consensus binding site functions to down-modulate IE62 activation, and interaction of IE62 with this sequence may result in loss or decrease of the ability of IE62 to recruit cellular factors needed for full promoter activation.[IE62] (Mus musculus) PubMed
5847.
These data indicate that the pre-S2 domain of the L protein serves an important role for virus assembly, but does not participate as part of the M protein or as a subdomain of the L protein in virus entry.[L] (Mus musculus) PubMed
5848.
Mutations E627K, D701N, and E677G had no major impact on virus replication in the respiratory tracts of mice and ferrets or on pathogenesis.[PB2] (Mus musculus) PubMed
5849.
Efficient budding of the tacaribe virus matrix protein z requires the nucleoprotein.(Z PROTEIN) (Mus musculus) PubMed
5850.
The ORF3 protein of hepatitis E virus was found to interact with CIN85 and compete with the formation of the growth factor receptor-Cbl-CIN85 complex, resulting in the reduced ubiquitination of CIN85.[ORF3] (Mus musculus) PubMed
5851.
The structure reveals variability in the order and position of a small domain, which forms a lid for the active site and serves to capture conformations likely to exist during the catalytic cycle.[glutathione synthetase] (Mus musculus) PubMed
5852.
The minicircle-encoded antisense transcripts, which are stabilized by RET1-catalyzed uridylylation, may direct a nucleolytic cleavage of multicistronic precursors.[RET1] (Mus musculus) PubMed
5853.
palH plays a very important role in controlling the alkaline protease level in A. oryzae. [palH] (Mus musculus) PubMed
5854.
Genetic ablation of the APT transporter results in rapid death of parasites.[APT] (Mus musculus) PubMed
5855.
Data presented here demonstrate that Stomatin like protein-2 is a novel tegument protein located in the host-parasite interface.[Stomatin like protein-2] (Mus musculus) PubMed
5856.
we show a mitochondrial localization for 3-hydroxy-3-methyl-glutaryl Coenzyme A (HMG-CoA) synthase while mevalonate kinase is associated mainly with the glycosomal matrix. [3-hydroxy-3-methyl-glutaryl Coenzyme A synthase/ mevalonate kinase] (Mus musculus) PubMed
5857.
we show a mitochondrial localization for 3-hydroxy-3-methyl-glutaryl Coenzyme A (HMG-CoA) synthase while mevalonate kinase is associated mainly with the glycosomal matrix. [3-hydroxy-3-methyl-glutaryl Coenzyme A synthase/ mevalonate kinase] (Mus musculus) PubMed
5858.
we describe the cloning and characterisation of an S. mansoni bone morphogenetic protein(SmBMP). SmBMP is expressed throughout the mammalian life-cycle of the parasite in both male and female schistosomes. [bone morphogenetic protein/BMP] (Mus musculus) PubMed
5859.
However, both mutants with an altered N-terminal cysteine were inactive. (Mus musculus) PubMed
5860.
Based on these experimental data, the authors conclude that Trichomonas vaginalis malate dehydrogenase is negatively regulated by miR-1.[malate dehydrogenase] (Mus musculus) PubMed
5861.
Both XBcl9 and XPygo2 are required to induce supernumerary axis and dorsal gene activation in Xenopus embryos. [Pygo2] (Mus musculus) PubMed
5862.
This study analyzed the behavior of two highly homologous rice HKT transporters in plant cells, HKT2;1 and HKT2;2, that show differential potassium permeabilities in heterologous systems.[HKT2;1, HKT2;2] (Mus musculus) PubMed
5863.
This study demonstrates that the regulation of a mechanism of multidrug resistance genes and expression of virulence genes show considerable overlap; the role of ramA in both is demonstrated.[RamA] (Mus musculus) PubMed
5864.
These results suggest that PhaR regulates the expression of phaP in Rhodobacter sphaeroides FJ1.[PhaR] (Mus musculus) PubMed
5865.
the CRN7 role in chemotaxis and phagocytosis is through its effect on the actin cytoskeleton [CRN7] (Mus musculus) PubMed
5866.
by expression analysis of deoxynivalenol (DON)-induced samples using GeneChip Wheat Genome Array, a DON-resistance related gene TaUGT3 was cloned and characterized from a scab resistant wheat variety [UGT3] (Mus musculus) PubMed
5867.
Here, the authors show that deletion of 3 or 9 residues at the C terminus of IpaB leads to fast constitutive secretion of late effectors, as observed in a DeltaipaB strain.[IpaB] (Mus musculus) PubMed
5868.
Mp1p ligand binding domain 2 has a function as a fatty acid-binding protein [Mp1p] (Mus musculus) PubMed
5869.
The CEK1-mediated MAPK pathway is involved in beta-glucan exposure in a fungal pathogen, hence influencing dectin-1-dependent immune cell recognition.[CEK1] (Mus musculus) PubMed
5870.
ZmRdRP1 was involved in antiviral defense in maize. (Mus musculus) PubMed
5871.
All new variant Chlamydia trachomatis isolates from 2006 displayed an identical ompA genotype E and multilocus sequence typing MLST profile, which strongly indicates a clonal spread of the nvCT. (Mus musculus) PubMed
5872.
findings suggest ZmsHSP might have a function in cytokinin response in Zea mays[sHSP, Zea mays] (Mus musculus) PubMed
5873.
FgEnd1 is a putative member of the endocytic machinery, although it acts through a different mechanism from ScEnd3 or ScEnd4 of S. cerevisiae. End1. (Mus musculus) PubMed
5874.
CcCel6C consists of a distorted seven-stranded beta/alpha barrel and has an enclosed tunnel [CcCel6C] (Mus musculus) PubMed
5875.
findings show that a peroxidase (IMPer), secreted by the Anopheles gambiae midgut, and dual oxidase form a dityrosine network that decreases gut permeability to immune elicitors [IMPer] (Mus musculus) PubMed
5876.
Data suggest that LmaMPK7 protein kinase activity may be implicated in parasite growth control and thus relevant for the development of nonproliferating stages during the infectious cycle [MPK7]. (Mus musculus) PubMed
5877.
Data describe the identification and function of the dynamin-like protein DLP1 from the protist parasite Entamoeba histolytica [DLP1]. (Mus musculus) PubMed
5878.
study demonstrates the activity of IrvR is controlled in a manner analogous to that of the CI protein; it has ability to undergo autocleavage, which promotes proteolytic degradation of its DNA binding domain leading to derepression of irvA [IrvR] (Mus musculus) PubMed
5879.
HsfA4a of wheat and rice confers cadmium tolerance by upregulating metallothionein gene expression in planta. [TaHsfA4a] (Mus musculus) PubMed
5880.
HsfA4a of wheat and rice confers cadmium tolerance by upregulating metallothionein gene expression in planta. [OsHsfA4a] (Mus musculus) PubMed
5881.
The recombinant CYP704B2 protein catalyzed the hydroxylation of palmitic acid and unsaturated C18 fatty acids in the omega position of the carbon chain. CYP704B2 is required for synthesis of cutin monomers.[CYP704B2] (Mus musculus) PubMed
5882.
Reveal myozap as a previously unrecognized component of a Rho-dependent signaling pathway that links the intercalated disc to cardiac gene regulation and implicate it in the pathogenesis of cardiomyopathy. (Mus musculus) PubMed
5883.
(KcsA potassium channel) The technique of electron spin-echo envelope modulation by deuterium demonstrates that KcsA inserts into the membrane without creating water-accessible crevices along its protein surface. (Mus musculus) PubMed
5884.
Results indicate that FlgT functions to stabilize the flagellar apparatus at the pole of the cell. [FlgT] (Mus musculus) PubMed
5885.
The relationship of agr expression with biofilm formation in methicillin-resistant S. aureus strains isolated in Greek patients is reported.[agr] (Mus musculus) PubMed
5886.
A single nucleotide substitution in hyaluronate lyase, resulting in an amino acid change at position 199, was present in a highly-conserved region of the protein in isolates not producing active enzyme.[hylA] (Mus musculus) PubMed
5887.
Studies shoe that IFT144 and IFT139, two complex A proteins, are encoded by FLA15 and FLA17, respectively, and Temperature-sensitive mutations in FLA15 and FLA17 show defects in retrograde intraflagellar transport (IFT): [FLA15 and FLA17] (Mus musculus) PubMed
5888.
Results suggest that AspA and AspC interact with each other and are important for normal development, especially for preventing the inappropriate emergence of germ tubes and branches [AspA; AspC]. (Mus musculus) PubMed
5889.
full length gene, named TaGly I, was cloned, sequenced and characterized; TaGly I might play a role in response to diverse stresses in plants[Glyoxalase I] (Mus musculus) PubMed
5890.
study shows that PdkA & PdkB function as the key activation loop kinases; cells lacking PdkA & PdkB are defective in PKB activation, chemotaxis & fruiting body formation upon nutrient deprivation[PKBR1] (Mus musculus) PubMed
5891.
OsBIANK1 may be involved in regulation of disease resistance response in rice.[BIANK1 protein] (Mus musculus) PubMed
5892.
ILI1-Os IBH1 is a conserved pair of antagonistic HLH/bHLH transcription factors that function downstream of BZR1 to mediate brassinosteroid regulation of cell elongation. [ILI1; IBH1] (Mus musculus) PubMed
5893.
Taken together, the results presented here demonstrate a novel, submitochondrial localization of the cytosolic phospholipase A2like protein in Aspergillus oryzae.[cytosolic phospholipase A2-like protein] (Mus musculus) PubMed
5894.
The biochemical properties of site-directed mutants indicate that H45, C51, and C53 of GroES make up an oxidation-sensitive zinc-binding site that may donate the bound metal to a zinc acceptor.[GroES] (Mus musculus) PubMed
5895.
An important region in the hepatitis C virus (HCV) NS4B protein is identified which might be implicated in the HCV life cycle and possibly in the formation of the membranous web.[NS4B] (Mus musculus) PubMed
5896.
eight characteristic mutations in the HCV-1b core gene related to the occurrence of hepatocellular carcinoma were identified [1b core protein] (Mus musculus) PubMed
5897.
Temperature-accelerated molecular dynamics is applied to the GroEL subunit, a 55-kDa, three-domain protein, and HIV-1 gp120.[gp120] (Mus musculus) PubMed
5898.
The recombinant extracellular var2CSA region is correctly folded and it binds with high affinity and specificity to chondroitin sulfate A.[var2CSA] (Mus musculus) PubMed
5899.
Lana-1-induced serum response element activation was inhibited by the dominant-negative N-terminal domain of the human MED25 mediator subunit, suggesting that this subunit mediates Lana-1-induced serum response element activation.[Lana-1] (Mus musculus) PubMed
5900.
C. neoformans Rim101 is also activated by the cAMP/PKA pathway [Rim101] (Mus musculus) PubMed
5901.
Rice (Oryza sativa L.) has a plant-type phosphoenolpyruvate carboxylase, Osppc4, that is targeted to the chloroplast.[Osppc4] (Mus musculus) PubMed
5902.
Trypanosoma cruzi calreticulin interacts in vitro with both solid phase bound active C1s and C1.[calreticulin] (Mus musculus) PubMed
5903.
we describe the purification and characterization of PfSIP2, a member of the ApiAP2 family of putative transcription factors, as the unknown nuclear factor interacting specifically with cis-acting SPE2 motif arrays in subtelomeric domains. (Mus musculus) PubMed
5904.
Characterization of a single-thioredoxin (Trx) QSOX shows strong similarities with the double-Trx enzymes investigated so far; lack of a second Trx domain does not result in major changes in QSOX catalytic specificity.[quiescin sulfhydryl oxidase; QSOX] (Mus musculus) PubMed
5905.
CaMKII binding and phosphorylation sites on beta(2a) are concise but pivotal components of a molecular and biophysical and mechanism for early afterdepolarizations and impaired survival in adult cardiomyocytes.[CamKII, Cav1.2beta] (Mus musculus) PubMed
5906.
Study shows that Galphai2 function is mediated by its interaction with GDE2, a known regulator of motor neuron differentiation, and that disruption of the GDE2/Galphai2 complex in vivo causes motor neuron deficits analogous to Galphai2 ablation.[Galphai2] (Mus musculus) PubMed
5907.
Hpa is a novel harpin with two heptads for hypersensitive response. [Hpa] (Mus musculus) PubMed
5908.
compelling evidence that CueO is a cuprous oxidase [CueO] (Mus musculus) PubMed
5909.
In the present study, the authors confirm the specific binding of NS5B to one of the RNA stem-loop structures in the region, 5BSL3.2. (Mus musculus) PubMed
5910.
Employing the new technique of analytical ultracentrifugation with fluorescence detection we have, for the first time, shown that the K(D)(4-2) for Ec-PK1 is in the subnanomolar range, well below the concentrations used in kinetic studies. (Mus musculus) PubMed
5911.
PrtV protease has a role in Vibrio cholerae cytolysin-induced inflammatory response in human intestinal epithelial cells [PrtV] (Mus musculus) PubMed
5912.
results suggest that, in Synechocystis cells, RNA helicase CrhR regulates the low-temperature inducibility of molecular chaperonins GroES, GroEL1 and GroEL2, which are, in turn, essential for growth at low temperatures [CrhR] (Mus musculus) PubMed
5913.
evidences for intragenic recombination in PvMsp-5 were found in most populations except that from southern Thailand in which haplotype diversity and nucleotide diversity were exceptionally low.[merozoite surface protein-5] (Mus musculus) PubMed
5914.
Our data suggest a host-specific factor is required for efficient folding of plasmid-encoded toxin.[plasmid-encoded toxin] (Mus musculus) PubMed
5915.
a cell model with DC-SIGN transient transfection to study p38 mitogen-activated protein kinase (MAPK) signaling pathway in response to the E2 treatment [hepatitis C virus E2] (Mus musculus) PubMed
5916.
Substrate selectivity of glycerol-3-phosphate acyltransferase (EC 2. 3. 1. 15) of rice (Oryza sativa L.) was explored in a comparative study of acyltransferases from seven plant species.[GPAT] (Mus musculus) PubMed
5917.
significant differences between the human and Plasmodium dUTPases [dUTPase] (Mus musculus) PubMed
5918.
The SAP domain is required for association of XDppa2/4 to chromatin and for embryonic survival at later stages of development suggesting epigenetic programming events.[XDppa2/4] (Mus musculus) PubMed
5919.
The characterization of an NAD(+)-dependent and zinc containing alcohol dehydrogenase (ADH) from Thermus thermophilus (TTHADH) is described.[TTADH] (Mus musculus) PubMed
5920.
The experimental data support the idea that transmembrane proximal region of E1 might be involved in membrane destabilization and viral fusion.[E1 glycoprotein] (Mus musculus) PubMed
5921.
The interaction of two helical antimicrobial peptides, HPA3 and HPA3P, derived from RpL1, with planar supported lipid membranes was quantitatively analysed using two complementary optical biosensors.[RpL1] (Mus musculus) PubMed
5922.
We present soluble overexpression and molecular characterization of Aga50D. It had unique exo-lytic activity and was able to produce neoagarobiose directly from agarose. [Aga50D] (Mus musculus) PubMed
We identified a response regulator, VemR, that regulates Xcc pathogenesis. [VemR] (Mus musculus) PubMed
5925.
Overexpression of OsRAN2 in rice resulted in enhanced sensitivity to salinity, osmotic stress, and abscissic acid.[OsRAN2] (Mus musculus) PubMed
5926.
Our results show that ADE8 (encoding phosphoribosylglycinamide formyl-transferase) and GUA1 (GMP synthase) genes involved in purine biosynthesis are required for systemic candidiasis. [ADE8, GUA1] (Mus musculus) PubMed
5927.
Molecular dynamics simulations of hexameric PNP from Plasmodium falciparum (PfPNP), is described.[PfPNP] (Mus musculus) PubMed
5928.
C-terminal domain of the Pseudomonas aeruginosa OprM and the alpha-helical hairpin domain of Vibrio cholerae VceA play an important role in the assembly of a chimeric efflux pump.[VceA][VceB] (Mus musculus) PubMed
5929.
Pf332 is a molecule with a potential role to support merozoite invasion. Due to the high level of conservation in sequence, the novel DBL-domain of Pf332 is of possible importance for development of novel anti-malaria drugs and vaccines [Pf332] (Mus musculus) PubMed
5930.
report the high-resolution crystal structure of RrgA, a 893-residue elongated macromolecule whose fold contains four domains presenting both eukaryotic and prokaryotic origins. [RrgA] (Mus musculus) PubMed
5931.
The SsrB-dependent regulon of ancestral and horizontally acquired genes, is described.[SsrA, SsrB] (Mus musculus) PubMed
5932.
found that peptidoglycans derived from Gram-negative bacteria (Escherichia coli 0111:B4 and K12), are potent inducers of IL-1beta and IL-6 gene expression and were equal to, or more potent than, crude LPS.[IL-1beta] (Mus musculus) PubMed
5933.
Varicella-zoster virus IE4 protein interacts with SR proteins and exports mRNAs through the TAP/NXF1 pathway [IE4] (Mus musculus) PubMed
5934.
assessed distribution of the F290V resistant AChE1 in natural populations around the Mediterranean Sea; presence of duplicated alleles, associating a susceptible & a V copy of the ace-1 gene, was shown in most individuals analyzed for its presence [ace-1] (Mus musculus) PubMed
5935.
Results describe the regulation of neuronal K(2P)2.1 (KCNK2, TREK-1) channel activity by resting membrane potential [KCNK2]. (Mus musculus) PubMed
5936.
OsCSTLP1 has CMP-sialic acid transporter activity. On the other hand, OsCSTLP2 did not exhibit any nucleotide sugar transporter activity. [OsCSTLP1 and OsCSTLP2] (Mus musculus) PubMed
5937.
We have cloned and expressed a short tyrosinase-like enzyme from A. oryzae lacking a C-terminal domain and classifed it a catchol oxidase since it lacked activity on tyrosine. [AoCO4] (Mus musculus) PubMed
5938.
the CID1 C-type cyclin gene plays multiple roles in the regulation of vegetative growth, sexual development, conidiation, DON production, and pathogenicity [CID1] (Mus musculus) PubMed
5939.
Study we show that the dst2-1 mutant exhibits a blind phenotype during asexual spore production in addition to that in fruiting-body photomorphogenesis and that dst2 is predicted to encode a protein with a putative FAD-binding-4 domain. (Mus musculus) PubMed
5940.
data suggest that, by directly interacting with fibronectin, plasminogen- and fibronectin-binding protein B (PfbB) significantly increases the ability of S. pneumoniae to adhere to human epithelial cells [PfbB] (Mus musculus) PubMed
5941.
Viral-derived membrane interacting peptides all act via a similar mechanism, which is substantially different from that of the non-cell selective lytic peptide melittin.[Glycoprotein B] (Mus musculus) PubMed
5942.
Here, the authors show that ICP27 undergoes a head-to-tail intramolecular interaction but not head-to-tail or tail-to-tail intermolecular interactions.[ICP27] (Mus musculus) PubMed
5943.
Data present a novel, plasma membrane-localized sucrose transporter (Srt1) from the corn smut fungus Ustilago maydis and its characterization as a fungal virulence factor. [Srt1] (Mus musculus) PubMed
5944.
BmNOX is a secretory protein expressed heavily in the posterior mid gut, with weaker expression in the fore- and mid-gut regions [NADH-oxidoreductase-like protein, BmNox] (Mus musculus) PubMed
5945.
Prolyl isomerase activity is located in a typical FKBP domain, whereas chaperone function is associated with the autonomously folded insert-in-flap (IF) domain.[SlyD] (Mus musculus) PubMed
5946.
report the first crystal structures of Fis bound to high- and low-affinity 27-base-pair DNA sites [Fis] [no strain indicated] (Mus musculus) PubMed
5947.
The results show that TaSnRK2.4 is involved in the regulation of enhanced osmotic potential, growth, and development under both normal and stress conditions.[TaSnRK2.4] (Mus musculus) PubMed
5948.
The current knowledge about the structure and biosynthesis of PIA is summarized.[PIA] (Mus musculus) PubMed
5949.
LepA is involved in co-translational folding of proteins that are otherwise vulnerable to tellurite oxidation [LepA] (Mus musculus) PubMed
5950.
Ta-JA1 belongs to a mannose-specific lectin, which may confer a basal but broad-spectrum resistance to plant pathogens.[JA1] (Mus musculus) PubMed
5951.
These data suggest that Orysa;KRP3 is involved in cell cycle control of syncytial endosperm.[Orysa;KRP3] (Mus musculus) PubMed
5952.
the function of Nup98 extends beyond transport at the nuclear pore to include mRNA regulation in the cytoplasm [Nup98] (Mus musculus) PubMed
5953.
Unlike other CREB2 (ATF4) proteins, the ATF4 isolated from the gonads of Xenopus embryos contains a consensus phosphorylation site for protein kinase A (PKA).[PKA] (Mus musculus) PubMed
5954.
Depolarization increases phosphatidylinositol (PI) 4,5-bisphosphate level and KCNQ currents through PI 4-kinase mechanisms [KCNQ2 and KCNQ3] (Mus musculus) PubMed
5955.
report the identification of a soluble form of the pilus protein FimA from the culture supernatants of E. coli K1, Salmonella, and Shigella that can potently inhibit Bax-mediated release of cytochrome c from isolated mitochondria.[FimA] (Mus musculus) PubMed
5956.
For the first time, endogenous components of SCF (Cullin-1 and Skp1) were co-precipitated with Myxoma Nuclear factor, expressed in an infectious context, and without over-expression of any protein.[Myxoma Nuclear factor] (Mus musculus) PubMed
5957.
LAT functions as an anti-apoptosis factor during HSV-1 infection. [LAT] (Mus musculus) PubMed
5958.
The N-terminal domain of unliganded P3 is a tetrameric parallel coiled coil with a unique organization showing two successive four-stranded subdomains with opposite supercoiling handedness stabilized by a ring of interchain disulfide bridges.[P3] (Mus musculus) PubMed
5959.
This study highlights the fact that interactions of M1 with viral envelope proteins are essential to direct M1 to the plasma membrane for influenza virus particle release. (Mus musculus) PubMed
5960.
The authors showed that in addition to the E627K mutation, the influenza A virus PB2 mutation T271A enhances polymerase activity in human cells.[PB2] (Mus musculus) PubMed
5961.
These findings suggest that furin or a furin-like proprotein convertase facilitates duck hepatitis B virus infection by cleaving both the docking receptor and the viral large envelope protein.[viral large envelope protein] (Mus musculus) PubMed
5962.
report the identification of a soluble form of the pilus protein FimA from the culture supernatants of E. coli K1, Salmonella, and Shigella that can potently inhibit Bax-mediated release of cytochrome c from isolated mitochondria.[FimA] (Mus musculus) PubMed
5963.
All the data suggest that Classical swine fever virus NS2 protein modulate the cellular growth and cell cycle progression through inducing the S-phase arrest and provide a cellular environment that is advantageous for viral replication.[NS2] (Mus musculus) PubMed
5964.
structural modelling of the E. coli EfeO Cup domain identifies two potential metal-binding sites [EfeO] (Mus musculus) PubMed
5965.
These data indicate that the m74 gene product together with other viral proteins codetermines CMV spread and CMV entry into cells.[M74] (Mus musculus) PubMed
5966.
The isolation and characterization of 2 new alleles of merozoite surface protein alpha in P. vivax from Korean patients are reported. (Mus musculus) PubMed
5967.
ManA transcription is positively regulated by Clp and RpfF and induced by locust bean gum. [ManA] (Mus musculus) PubMed
5968.
we identified, SrcA, a multi-cargo secretion chaperone that is functionally integrated with the SPI-2-encoded type III secretion system and required for systemic infection in mice. (Mus musculus) PubMed
5969.
TgMORN1 is required for maintaining the structural integrity of the parasite posterior end (Mus musculus) PubMed
5970.
The mitogen-activated protein (MAP) kinase Hog1 controls CMV activation by osmotic stress through the ATF/CRE-related transcription factor Sko1 and the yeast osmostress factor Hot1.[Hot1, Sko1] (Mus musculus) PubMed
5971.
RecA and the SOS response are required for a substantial fraction of thymineless death.[RecA] (Mus musculus) PubMed
5972.
This study showed that E. coli could not enter the VBNC state in the lack of EnvZ product under the stress of osmolarity, pH and starvation and the relationship between EnvZ and VBNC state are not affected by pH, osmolarity and starvation.[EnvZ] (Mus musculus) PubMed
5973.
IHF positions SmcR to contact RNAP by looping the vvpE regulatory DNA, thus allowing precise control of the expression level of VvpE during the pathogenesis of V. vulnificus [VvpE] (Mus musculus) PubMed
5974.
Data demonstrated the binding of BeF3- to HpCheY1 and the interaction between BeF3--HpCheY1 and HpFliM. Comparison of the BeF3--HpCheY1 and BeF3--EcCheY structures revealed a distinctive FliM binding surface. [CheY1] (Mus musculus) PubMed
5975.
Using a bioinformatic approach, we show that SporoSAG clusters with the SAG2 subfamily of the SAG1-related superfamily (SRS) and is non-polymorphic among the 11 haplogroups. (SporoSAG) (Mus musculus) PubMed
5976.
6S RNA -35 binding to sigma(70) RNA polymerase holoenzyme can regulate expression from "strong" and "weak" -35 DNA promoters and 6S RNA release rates may have been fine tuned during evolution to correctly regulate cellular levels of transcription (6S RNA) (Mus musculus) PubMed
5977.
xlEPO shares structural and functional similarities and differences with mammalian counterparts, and regulation of xlEPO expression and its influence on the erythropoietic system appears to be unique. EPO. (Mus musculus) PubMed
5978.
show that Xenopus Bsx (Xbsx) is expressed rhythmically in postmitotic photoreceptor precursors, reaching a peak during the night, with a cycle that is complementary to the daily rhythms of S-phase entry displayed by pineal cells.[ Bsx ] (Mus musculus) PubMed
5979.
The relevance of CdpA in Burkholderia pseudomallei virulence was demonstrated by a 3-fold reduction in invasion of human lung epithelial cells and a 6-fold reduction in cytotoxicity on human macrophage cells infected with the cdpA mutant.[cdpA] (Mus musculus) PubMed
5980.
These results suggest ERK1 and ERK2 have different roles in G protein-mediated signaling during growth and development.[ERK1, ERK2] (Mus musculus) PubMed
5981.
The authors found that an amphipathic helix located within the M2 cytoplasmic tail is able to bind cholesterol, and they speculate that M2 cholesterol binding is essential for both filament formation and the stability of existing viral filaments. (Mus musculus) PubMed
5982.
Ser/Thr phosphorylation by PknB/Stk and dephosphorylation by Stp play an important role in central metabolic processes such as cell wall metabolism, glycolysis, citrate cycle, purine-, pyrimidinesynthesis, and translation. [REVIEW/Stk/PknB/Stp] (Mus musculus) PubMed
5983.
Changes in pulmonary alveolar ultrastructure and decreased expression of SP-A occur in fetal rabbits after intrauterine infection. [surfactant protein A] (Mus musculus) PubMed
5984.
The results indicated that the MPR300 in chicken embryo fibroblasts cells plays a key role in sorting and trafficking of these soluble hydrolases.[MPR300] (Mus musculus) PubMed
5985.
study demonstrates that the deviation from Michaelis-Menten behavior for GpdQ at lower pH when bpNPP is the substrate is due to the sequential hydrolysis of both bpNPP and its monoester product pNPP [Glycerophosphodiesterase (GpdQ)] (Mus musculus) PubMed
5986.
These results indicate that stringent conditions are present during infection and that RSH-dependent derepression of CodY-regulated genes is essential for virulence in Staphylococcus aureus.[RSH] (Mus musculus) PubMed
5987.
Controlling the temperature and pH of KcsA samples produced three distinct methyl-TROSY and NOESY spectra, corresponding to the resting, activated, and inactivated states. [KcsA] (Mus musculus) PubMed
5988.
Incubation with lipopolysaccharides did not affect the binding of the B-subunits of heat-labile enterotoxin of human isolates to blood group A-carrying glycosphingolipids.[heat-labile enterotoxin] (Mus musculus) PubMed
5989.
These results demonstrate that deglycosylation of a human serum glycoconjugate(s) by the combined effects of NanA, BgaA, and StrH, is important for resistance to complement phagocytic killing of Streptococcus pneumoniae.[BgaA & StrH] (Mus musculus) PubMed
5990.
The logarithm of the catalytic efficiency for R274N/R276N, log(k(cat)/K(m)) exhibited the best linear correlation with the heat-denaturation temperature midpoint of the corresponding acylated complex of E166A/R274N/R276N. (beta-lactamase Toho-1) (Mus musculus) PubMed
5991.
Tax binds the cyclin D1 promoter-proximal cyclic AMP response element (CRE) in the presence of phosphorylated CREB (pCREB) in vitro, and together the Tax-pCREB complex recruits the cellular co-activator p300 to the promoter. (Mus musculus) PubMed
5992.
The data suggest that centromeric RNA helps to recruit CENPC to the inner kinetochore by altering its DNA binding characteristics.[CENPC] (Mus musculus) PubMed
5993.
Slit acts via Robo2 in dendrites as a branching/growth factor but not in guidance, while Robo2 and Robo3 function in concert in axons to mediate axonal interactions and respond to Slits as guidance factors [Robo2] (Mus musculus) PubMed
5994.
Identified are two independent sites in tubulin, which are critical for kinesin motility. [kinesin] (Mus musculus) PubMed
5995.
FRH has a role in regulating the phosphorylation and stability of Neurospora circadian clock protein FRQ [FRH] (Mus musculus) PubMed
5996.
The authors observed that the putative Staphylococcus saprophyticus virulence factors Ssp and SdrI were important for persistence, but not for initial colonization, in the murine urinary tract.[Ssp & SdrI] (Mus musculus) PubMed
5997.
TgMYST-B is a MYST family lysine acetyltransferase that facilitates ataxia telangiectasia mutated (ATM) kinase-mediated DNA damage response in Toxoplasma gondii [MYST-B] (Mus musculus) PubMed
5998.
These results demonstrated that the expression of GRA1 in ER of macrophages promotes both growth and adherence of macrophages and modulates the intracellular calcium release stimulated by arachidonic acid [GRA1] (Mus musculus) PubMed
5999.
E. coli DUF299 catalyzes both the ADP-dependent inactivation and the Pi-dependent activation of Phosphoenolpyruvate synthetase (DUF299). (Mus musculus) PubMed
6000.
The virulence of the sspA(-) mutant was markedly lower than the wild type in pigs as demonstrated in experimental infections.[sspA] (Mus musculus) PubMed
6001.
Microarrays confirmed the global regulatory role of SpxA and SpxB. SpxB had a secondary role in regulation of oxidative stress genes but appeared to play a larger role in controlling processes associated with cell wall homeostasis. [SpxB] (Mus musculus) PubMed
6002.
The authors identify and characterize a Cryptococcus neoformans homolog of the Saccharomyces cerevisiae BIM1 gene, and establish the importance of BIM1 for proper filamentous growth of Cryptococcus neoformans.[BIM1] (Mus musculus) PubMed
6003.
These results indicate that selective binding of gp82 to gastric mucin may direct Trypanosoma cruzi metacyclic trypomastigotes to stomach mucosal epithelium in oral infection. (Mus musculus) PubMed
6004.
The structure of the 3' region of the cagA gene in Helicobacter pylori isolated from an Iranian population was Western type. (Mus musculus) PubMed
6005.
data identify SAND-1 (Mon1) and CCZ-1 (Ccz1) as critical and evolutionarily conserved components regulating the processing of ingested apoptotic cell corpses [CCZ-1] (Mus musculus) PubMed
6006.
The association between daily cotrimoxazole-prophylaxis and infection with P. falciparum containing mutations in the dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) genes among HIV patients is reported.[DHFR; DHPS] (Mus musculus) PubMed
6007.
The results of surveillance for mutations in dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhps)in P. falciparum during introduction of artesunate-cotrimoxazole combined therapy in Mozambique are reported.[DHFR; DHPS] (Mus musculus) PubMed
6008.
Two novel tachykinin-like peptides named tachykinin-DR1 and -DR2 were identified from skin secretions of Danio rerio [tachykinin-DR1 and tachykinin-DR2] (Mus musculus) PubMed
6009.
Stromal processing peptidase is essential for chloroplast biogenesis at the early growth stage and for rice root development. [SPP] (Mus musculus) PubMed
6010.
These results suggest that some protein fragments of CLAG-9 may be part of the molecular machinery used by malaria parasites to invade erythrocytes.[CLAG-9] (Mus musculus) PubMed
6011.
Data demonstrate that there is no competition for actin-binding between PfEMP3 and Pf332, suggesting that they bind to different target sequences in actin [Pf332]. (Mus musculus) PubMed
6012.
Leak K(+) channels (TASK-1) seem to be importantly involved in the initiation of the oxygen sensing mechanisms of the rabbit carotid body.[TASK-1] (Mus musculus) PubMed
6013.
These results suggest that SaHPF is a key protein involved in 100S ribosome formation in S. aureus.[SaHPF] (Mus musculus) PubMed
6014.
Mutagenesis and spectroscopic analyses were performed to identify the heme axial ligands in HtsA and to characterize axial mutants of HtsA [HtsA] (Mus musculus) PubMed
6015.
The crystal structures of Get3 in ADP-bound and nucleotide-free forms at 3.0 A and 2.8 A resolutions, respectively, are reported.[Get3] (Mus musculus) PubMed
6016.
The white-collar complex is the key element for con-10 activation.[Con-10] (Mus musculus) PubMed
6017.
EBNA1 inhibits the canonical NF-kappaB pathway in carcinoma lines by inhibiting the phosphorylation of IKKalpha/beta.[EBNA1] (Mus musculus) PubMed
6018.
Changes in the expression of Sema3A in spinal cord and NP-1 in L6 dorsal root ganglion after partial root rhizotomy may be involved in collateral sprouting of spared root in superficial lamina. [Sema3A; NP-1] (Mus musculus) PubMed
6019.
The first structure of a pneumococcal autolysin, that of the LytC lysozyme, has been solved in ternary complex with choline and a pneumococcal peptidoglycan (PG) fragment. (Mus musculus) PubMed
6020.
crystal structure of the N-terminal domain of Encephalitozoon cuniculi Cdc27 reveals a homo-dimeric structure, composed predominantly of successive TPR motifs [Cdc27, Apc3] (Mus musculus) PubMed
6021.
These results indicated that SigN was involved in morphological development, secondary metabolism and stress responses in Streptomyces coelicolor.[SigN] (Mus musculus) PubMed
6022.
[env glycoprotein] An immunodominant peptide derived from West Nile virus (WNV) envelope glycoprotein is paired with HLA-A*0201 trimer in a vaccine model that elicits a robust epitope-specific CD8+ T cell cytotoxic response against lethal WNV infection. (Mus musculus) PubMed
6023.
These results indicate a possible role for Hwp2 in adhesion and invasiveness.[Hwp2] (Mus musculus) PubMed
6024.
The pvmdr1 analysis revealed the existence of single (85.7%) and double (14.3%) mutant haplotypes (Mus musculus) PubMed
6025.
(adrenergic alpha1L receptor) A typical alpha1L adrenoceptor phenotype with extremely low affinity for prazosin is exclusively expressed in the iris of pigmented rabbits. (Mus musculus) PubMed
6026.
Ifr1 restores fertility through reducing either the transcription rate of B-atp6-orf79 or the stability of its primary transcripts. (Mus musculus) PubMed
6027.
Both OsRR3 and OsRR5 mainly act as negative regulators of cytokinin signaling.[OsRR3, OsRR5] (Mus musculus) PubMed
6028.
There was a significant difference in the prevalence of each MSP1 allelic variant both between age-groups and between the various categories of anaemia considered (P<0.0001 for each), with the highest number of alleles occurring in severe anaemia. (Mus musculus) PubMed
6029.
The result confirms that PglB is solely responsible for the oligosaccharyltransferase activity and complements the finding that PglB exhibits relaxed sugar substrate specificity.(PglB) (Mus musculus) PubMed
6030.
ERAP32 and ERAP18 are trypanosome-specific ER-localized proteins with a major role in VSG protein export [ERAP32, ERAP18] (Mus musculus) PubMed
6031.
BICP27 shuttles between the nucleus and the cytoplasm by the functional nuclear export signal and nuclear localization signal through a CRM1-dependent nuclear export pathway and a Ran dependent nuclear import pathway.[BICP27] (Mus musculus) PubMed
6032.
Sequence analysis of 3a and 3b genes of Chinese field strains showed that the strains were genetically diverse among themselves as well as in comparison with reference strains. [3a protein, 3B protein] (Mus musculus) PubMed
6033.
The CYP102B1 fatty acid hydroxylase metabolism of arachidonic acid produced 11,12-epoxyeicosa-5,8,14-trienoic acid in addition to 18-hydroxy arachidonic acid and 14,15-epoxyeicosa-5,8,11-trienoic acid.[CYP102B1] (Mus musculus) PubMed
6034.
the ultra-weak photon emission of the E. coli with and without the Yhha gene (Mus musculus) PubMed
6035.
CLP24 is a novel regulator of VEGFR-2 and VEGFR-3 signaling pathways and of normal lymphatic vessel structure [Claudin-like protein of 24 kDa (CLP24)] (Mus musculus) PubMed
6036.
The isoforms of Xenopus Cdc4,xCdc4alpha is found to be dynamically expressed throughout early Xenopus development, with particular enrichment in neural crest and neural crest-derived tissues. [xCdc4alpha] (Mus musculus) PubMed
6037.
CLP24 is a novel regulator of VEGFR-2 and VEGFR-3 signaling pathways and of normal lymphatic vessel structure [Claudin-like protein of 24 kDa (CLP24)] (Mus musculus) PubMed
6038.
cagA in situ expression is increased in H pylori-infected children with peptic ulcers and may play a role in the pathogenesis of peptic ulcer disease during childhood [cagA] (Mus musculus) PubMed
6039.
"flipped" conformation of selectivity filter present in E71A allows weaker extracellular & stronger intracellular TEA binding, whereas higher PG content decreases channel conductivity and stabilizes the channel open "flipped" state[KcsA] (Mus musculus) PubMed
6040.
Study demonstrated that Cul4 and DDB1 are associated with the histone methyltransferase DIM-5 protein and are essential for DNA methylation in vivo. [Cul4] (Mus musculus) PubMed
6041.
Solved is the structure of the autoinhibited (apo) and activated (calcium-bound) conformation of calcium-dependent protein kinase from the apicomplexan parasite Toxoplasma gondii.[calcium-dependent protein kinase] (Mus musculus) PubMed
6042.
Neurospora PARP orthologue (NPO) may regulate aging by impacting NAD+/NAM availability, thereby influencing Sirtuin activity, or they may function in alternative NAD+-dependent or NAD+-independent aging pathways.[NPO] (Mus musculus) PubMed
6043.
Results indicate that NrdB protein, and most likely RNR protein, is closely linked to the replication proteins or replisome at the replication fork ( NrdB ). (Mus musculus) PubMed
6044.
These data indicate that the Aspergillus oryzae PlaA and PlaB secretory phospholipase enzymes display distinct, presumably non-redundant, physiological functions.[PlaB] (Mus musculus) PubMed
6045.
The study shows the crystal structure of the reduced form of R. marinus high-potential iron-sulfur protein (HiPIP) solved by the single-wavelength anomalous diffraction method,refined to 1.0 A resolution.[high-potential iron-sulfur protein] (Mus musculus) PubMed
6046.
These results collectively suggest that AMA-1 displays high genetic polymorphism among Myanmar Plasmodium vivax isolates with highly diversifying selection at domain I.[AMA-1] (Mus musculus) PubMed
6047.
Variance of vacA genotypes of local H. pylori isolates mainly lied in mid-region.[VacA] (Mus musculus) PubMed
6048.
Our discovery of previously undocumented nonfunctional phr1 alleles suggests that there are likely to be other loss-of-function mutations segregating in Oryza sativa around the world. [Phr1 protein, Oryza] (Mus musculus) PubMed
6049.
Yeast two-hybrid analysis revealed that the full-length PTP1, PTP2 and PTP3 proteins of Encephalitozoon cuniculi interact with each other in vivo.[PTP1 , PTP2 and PTP3] (Mus musculus) PubMed
6050.
E2F5 may play important roles in zebrafish brain, eye and ovarian development.[zE2F5a and zE2F5b] (Mus musculus) PubMed
6051.
The ancient OsMADS6 gene is able to specify "floral state" by determining floral organ and meristem identities in monocot crop rice. (Mus musculus) PubMed
6052.
The authors showed that Hp-DcuA, the fourth component of these novel deamidase-transport systems, was as crucial as Hp-gammaGT, Hp-AnsB, and Hp-GltS for animal model colonization.[AnsB] (Mus musculus) PubMed
6053.
find that two knotted methyltransferases, YibK and YbeA, can exist in a trefoil-knot conformation even in their chemically unfolded states.[YibK] (Mus musculus) PubMed
6054.
The crystal structure of Plasmodium falciparum D-tyrosyl-tRNATyr deacylase was determined using the iodide-SAD phasing method.[D-tyrosyl-tRNATyr deacylase] (Mus musculus) PubMed
6055.
H. pylori is likely to adhere to the gastric mucosa with sialic acid binding adhesin(SabA). Expression is frequently switched "on" or "off", suggesting that SabA expression can rapidly respond to changing conditions in the stomach. [REVIEW] (Mus musculus) PubMed
6056.
The TBF1 protein of Saccharomyces cerevisiae is required for full snoRNA expression, yet it does not influence nucleosome positioning at snoRNA promoters. (Mus musculus) PubMed
6057.
Intersubunit electrostatic interaction among Glycine Receptor subunits contributes to the stabilization of the closed channel state, and its disruption represents a critical step in GlyR activation. [GlyR-alpha] (Mus musculus) PubMed
6058.
The crystal structure of release factor 2 bound to ribosome with an aminoacyl tRNA substrate analog at the ribosomal P site, at 3.1 A resolution, is reported.[release factor 2] (Mus musculus) PubMed
6059.
Strains with a deletion of vttR(A) or vttR(B) showed attenuated colonization in vivo, indicating that the type three secretion system -encoded regulatory proteins play a role in virulence.[vttR(A), vttR(B)] (Mus musculus) PubMed
6060.
The CvfA-enolase complex in Streptococcus pyogenes is involved in the regulation of virulence gene expression by controlling RNA degradation according to nutritional stress. (Mus musculus) PubMed
6061.
The study shows the crystal structure of the Sac phosphatase domain of yeast Sac1.[Sac1] (Mus musculus) PubMed
6062.
Formation of the genetically transmissible prion state is a two-step process that involves an ancient system for the asymmetric inheritance of damaged proteins and heritable changes in the extent of prion fragmentation.[Sup35] (Mus musculus) PubMed
6063.
A systematic analysis of Magic-angle spinning (MAS) solid-state NMR protein spectra for two protein systems--GB1, a 6 kDa nanocrystalline protein and DsbA, a 21 kDa nanocrystalline protein, are presented.[DsbA] (Mus musculus) PubMed
6064.
A map-based cloning approach pinpointed an Ostetratricopeptide repeat (TPR) as a strong candidate of FLO(a) and the proteins that contain TPR motifs might play a significant role in rice starch biosynthetic pathways.FLO(a) (Mus musculus) PubMed
6065.
a TFA-type zinc finger protein gene ZFP207 (GenBank assession number AK063147.1) was cloned from rice variety Jiucaiqing by RT-PCR approach.[ZFP207] (Mus musculus) PubMed
6066.
The crystal structure of Salmonella FliT at 3.2-A resolution, is reported.[FliT] (Mus musculus) PubMed
6067.
The anterior expression is not fixed in the period of limb development, but the expression domains of Mkp3, Sef and TSK change considerably from the distal domain to the anterior domain [Mkp3] (Mus musculus) PubMed
6068.
H. pylori urease may exist in aggregated and dissociated forms, each with intact function but differing kinetics that may be of importance in maximizing urea breakdown at varying urea concentrations in vivo. [Urease/ H. pylori ATCC 49503] (Mus musculus) PubMed
6069.
The results suggested that SCO3900 encodes a negative regulator participating in morphological differentiation of Streptomyces coelicolor by influencing the expression of its downstream genes.[SCO3900] (Mus musculus) PubMed
6070.
Igo1/2 may have an evolutionarily conserved role in fungal mRNA stability control. (Mus musculus) PubMed
6071.
The detailed location of a low-tillering gene, Ltn, which has been localized on chromosome 8 in Aikawa 1, was confirmed by molecular mapping.[Ltn] (Mus musculus) PubMed
6072.
high-resolution solution NMR spectra of OmpX kept water-soluble by either amphipol A8-35 or the detergent dihexanoylphosphatidylcholine. (Mus musculus) PubMed
6073.
Data demonstrates that the RNA recognition motif of Rna15 displays a strong preference for GU-rich RNA, mediated by a binding pocket that is entirely conserved in both yeast and mammalian Rna15 orthologues (Rna15). (Mus musculus) PubMed
6074.
This study concluded that further work should be performed to elucidate the role of platelet activating factor (PAF) in the pathophysiology of inflammatory airway disease.[PAF] (Mus musculus) PubMed
6075.
These results demonstrated that the PmrAB system in Erwinia amylovora renders the pathogen more susceptible to polymyxin B and acidic pH, but more resistance to excess iron.[PmrA & PmrB] (Mus musculus) PubMed
6076.
RamR mutation and presence of plasmid borne tet(A)variant assoaciated with TN 1721 in A clinical isolate Salmonella enterica serovar Hadar resistant to tigecylcine. [ramR, tet(a)] (Mus musculus) PubMed
6077.
The function of MukB hinge appears to be limited to dimerization of two copies of MukB molecules.[MukB] (Mus musculus) PubMed
6078.
Follow-up of the mutant clone that was most heavily impaired in biofilm formation led to the identification of a novel 285 kDa multi-domain protein which the authors have termed biofilm-promoting factor A (BpfA).[BpfA] (Mus musculus) PubMed
6079.
Pup1 has the potential to improve yield in phosphorus-deficient and/or drought-prone environments and in diverse genetic backgrounds.[Pup1] (Mus musculus) PubMed
CagA protein negatively regulates the functions of DC via CagA phosphorylation and that cagA-positive H. pylori strains suppress host immune responses resulting in their chronic colonization of the stomach. (Mus musculus) PubMed
6082.
A model for HpNikR activation involves a first activation step where occupancy of the high-affinity site establishes a hydrogen bond network required for DNA binding. (Mus musculus) PubMed
6083.
Suppression of rpS3a caused by RNAi did not permanently block ovarian development. [RpS3a] (Mus musculus) PubMed
6084.
zfMC2R is not functional in the absence of MRAP expression.[MRAP1, MRAP2a, MRAP2b] (Mus musculus) PubMed
6085.
These data indicate that the galU gene contributes to Xanthomonas citri subsp. citri growth in intercellular spaces and is involved in extracellular polysaccharides and capsular polysaccharide synthesis and biofilm formation. (Mus musculus) PubMed
6086.
found that DIM-7 is essential for recruitment of DIM-5 to form heterochromatin.[DIM-7] (Mus musculus) PubMed
6087.
higher-level thymidine phosphorylase expression is correlated with LMP1 positivity in NPC biopsy samples (LMP1). (Mus musculus) PubMed
6088.
FtsK trimers with a single catalytic mutation give translocases impaired in displacing a DNA roadblock. [FtsK] (Mus musculus) PubMed
6089.
Complete data sets were collected to 1.5 and 1.4 A resolution, respectively, from single crystals of DdlB under cryogenic conditions using synchrotron radiation.[DdlB] (Mus musculus) PubMed
6090.
Results show that NRL1 gene was mapped to chromosome 12 and encodes the cellulose synthase-like protein D4 (OsCslD4): [NRL1] (Mus musculus) PubMed
6091.
The 36.5 kDa m164 gene product is identified here as an integral type-I membrane glycoprotein trafficking within the endoplasmic reticulum (ER) and outer nuclear membrane with an high lateral membrane motility. (Mus musculus) PubMed
6092.
Crystals of apo Dictyostelium discoideum phenylalanine hydroxylase (DicPAH; residues 1-415) and the DicPAH-dihydrobiopterin-Fe(III) complex diffracted to 2.6 and 2.07 A resolution. [phenylalanine hydroxylase ] (Mus musculus) PubMed
6093.
The 480-kDa complex contributes to template-dependent RdRP activities. [RdRP] (Mus musculus) PubMed
6094.
TrwB has a role in recognizing G-quadruplex structures as loading sites on the DNA [TrwB] (Mus musculus) PubMed
6095.
The oral administration of the expressed alpA induced protective immunity in mice. [alpA] (Mus musculus) PubMed
6096.
These results indicate that GlxR plays an important role in carbon catabolite repression as well as in acetate metabolism.[GlxR] (Mus musculus) PubMed
6097.
cytochrome P450 gene has been isolated from the insecticide-susceptible strain of the red flour beetle, Tribolium castaneum (Herbst) and the nucleotide sequence determined. [CYP345D3 ] (Mus musculus) PubMed
6098.
The gene coding for rice chloroplastic L-myo-inositol-1-phosphate synthase (MIPS; EC 5.5.1.4) has been identified.[MIPS] (Mus musculus) PubMed
6099.
exoerythrocytic P. berghei parasites express a potent cysteine protease inhibitor (PbICP) which has an important function in sporozoite invasion and is capable of blocking hepatocyte cell death[PBICP] (Mus musculus) PubMed
6100.
The changes of HSP 70 mRNA and c-fos mRNA expression in skeletal muscle and cardiac muscle can be used as an indicator to distinguish antemortem from postmortem electrocution. [HSP70; c-fos] (Mus musculus) PubMed
6101.
One fur mutant was attenuated on a host plant, thus indicating that fur has important roles in the virulence of Xanthomonas campestris pv. campestris.[fur] (Mus musculus) PubMed
6102.
Hydrophobicity of the VP5 is required for membrane disruption during rotavirus cell entry. [VP5] (Mus musculus) PubMed
6103.
CaPTC6 is the functional homologue of Saccharomyces cerevisiae PTC6. [PCT6] (Mus musculus) PubMed
6104.
CaPTC6 is the functional homologue of Saccharomyces cerevisiae PTC6. [PCT6] (Mus musculus) PubMed
6105.
ZmPIN1 proteins are polarly localized in the embryo cell plasma membrane from the first developmental stages, indicating the existence of ZmPIN1-mediated auxin fluxes. [PIM1] (Mus musculus) PubMed
6106.
low-density lipophorin (LDLp), results suggest that LDLp is required for the delivery of lipids for organogenesis during embryogenesis. (Mus musculus) PubMed
6107.
Ppd-D1 haplotypes in 492 wheat varieties from diverse geographic locations and 55 accessions were identified.[Ppd-D1] (Mus musculus) PubMed
6108.
MtMSBP1 is critical for mycorrhiza development.[MtMSBP1] (Mus musculus) PubMed
6109.
It was concluded that Ku86 deficiency accelerates high NaCl induced cellular senescence in cultured cells, C. elegans, and knockout mouse kidney.[KU86] (Mus musculus) PubMed
6110.
findings are consistent with the idea that the N-terminal domain of Kdo transferase may bind the acceptor lipid substrate, whereas the C-terminal domain binds the donor nucleotide (Kdo transferase) (Mus musculus) PubMed
6111.
NMR characterization of the interaction of the Salmonella type III secretion system protein SipD and bile salts (Mus musculus) PubMed
6112.
findings are consistent with the idea that the N-terminal domain of Kdo transferase may bind the acceptor lipid substrate, whereas the C-terminal domain binds the donor nucleotide (Kdo transferase) (Mus musculus) PubMed
6113.
In wt & RIC1 cells, gammaH2AX foci formed after gamma-irradiation, but they disappeared more quickly in the RIC1 cells. Instability of gammaH2AX foci in RIC1 cells cause an aberration of the DNA damage response. RIC1 (Mus musculus) PubMed
6114.
amphioxus SARM appears unique in that it may play dual functions in neural development and innate immunity by targeting amphioxus TLR signaling. (Mus musculus) PubMed
6115.
Mgm1p mediates fusion through oligomerization, GTP hydrolysis, and lipid binding in a manner similar to those of other dynamin mechanoenzymes.[Mgm1p] (Mus musculus) PubMed
6116.
transcriptional factor UreR is involved in the temperature dependency of urease activity, two nucleotides within the ureR promoter region are of particular importance for the urease activity dependency [UreR/Urease/V parahaemolyticus TH3996 and AQ4673] (Mus musculus) PubMed
6117.
These results indicate the existence of a conformationally well-defined heme pocket that involves amino acids located in the proximity of H130, of CcmE.[CcmE] (Mus musculus) PubMed
6118.
These results show that the type II thioesterase evolves its distinctive ability to recognize the aberrant intermediates from the versatile catalytic platform of hotdog proteins.[EntH] (Mus musculus) PubMed
6119.
Hsp30 is necessary during lethal heat stress.[Hsp39] (Mus musculus) PubMed
6120.
structures revealed the mode of binding of Rap1 and TFIIA to TFIID, as well as a reorganization of TFIIA induced by its interaction with Rap1 [TFIIA, Rap1, TFIID; strain not specified] (Mus musculus) PubMed
6121.
Site-directed mutagenesis of residues in the BC loop (residues 329-333) of the envelope (E) protein domain III in a West Nile virus demonstrated a critical role for residues in this loop in the function and antigenicity of the E protein.[E] (Mus musculus) PubMed
6122.
NMR relaxation studies of an RNA-binding segment of the rous sarcoma virus gag polyprotein in free and bound states: a model for autoinhibition of assembly (Mus musculus) PubMed
6123.
HBZ is encoded on the proviral antisense & transcribed from a promoter in the 3' LTR. It inhibits expression of the other viral proteins by blocking the interaction of Tax & ATF/CREB & the recruitment of CBP/p300 by Tax on the promoter. HBZ. (Mus musculus) PubMed
6124.
The authors show that P34 is a sequence non-specific single-stranded RNA-binding protein in vitro.[P34] (Mus musculus) PubMed
6125.
Duplicated pair of GIF1 and OsCIN1 has experienced sub-functionalization that selection acts independently on each duplicate towards different functional specificity. [GIF1, CIN1] (Mus musculus) PubMed
6126.
Biallele and triallele polymorphism of phosphoglucomutase locus was determined [phosphoglucomutase] (Mus musculus) PubMed
6127.
MviN is regulated by LuxO and is involved in the pathogenicity. [MviN, LuxO] (Mus musculus) PubMed
6128.
Data show that melatonin surges in the final stages of chick retinal cell differentiation in culture are essential for development of cells expressing alpha8 nAChR in full functional form [nAChR alpha8]. (Mus musculus) PubMed
6129.
VacA p58 induced apoptosis in gastric epithelial carcinoma cells; apoptotic process is associated with the up-regulation of Bax/VDAC1 and downregulation of Bcl-2 [VacA] (Mus musculus) PubMed
The authors demonstrated that GlnR and the GlnR box (ATGTNAN(7)TNACAT) were involved in the transcriptional repression of clusters of genes encoding proteins involved in glutamine and glutamate metabolism under acidic challenge.[GlnR] (Mus musculus) PubMed
6132.
mga mutants displayed an increased attachment and internalization rate for eukaryotic cells.[mga] (Mus musculus) PubMed
6133.
The study not only reveals the key structural elements and residues of sTrpRS involved in the recognition and binding of the ligands, but also provide new insights into the catalytic mechanism of Trp activation by eukaryotic TrpRSs (TrpRS). (Mus musculus) PubMed
6134.
Metabolic control of vH(+)-ATPase involving regulation of its assembly state by elements of the glycolytic pathway could provide a means to adapt rumen epithelial cells ATP consumption according to energy availability.[vH(+)-ATPase] (Mus musculus) PubMed
6135.
The authors show that expression of all genes of a gene cluster responsible for ustilagic acid biosynthesis depends on Rua1, a nuclear protein of the C(2)H(2) zinc finger family, whose gene is located within the gene cluster.[Rua1] (Mus musculus) PubMed
6136.
The rpoX gene is involved in biofilm formation and stress response but the effects are controlled by colony phase variation in V. alginolyticus.[rpoX] (Mus musculus) PubMed
6137.
Lack of Apobec2-related proteins causes a dystrophic muscle phenotype in zebrafish embryos (Mus musculus) PubMed
6138.
The AceK structure reveals a eukaryotic protein-kinase-like domain containing ATP and a regulatory domain with a novel fold [aceK; no strain specified] (Mus musculus) PubMed
6139.
RNAIII represses the synthesis of staphylocoagulase through a direct binding with the mRNA[RNAIII and staphylocoagulase] (Mus musculus) PubMed
6140.
we report the high-resolution structure of the catalytically active amidase domain AmiE (amidase S. epidermidis) from the major autolysin of S. epidermidis[azutolysin] (Mus musculus) PubMed
6141.
Snf1 modulates the level of eIF2alpha phosphorylation by different mechanisms, depending on the kind of nutrient deprivation existing in cells.[Snf1, Gcn2, Glc7, Sit4, eif2 alpha] (Mus musculus) PubMed
6142.
prd-1 and prd-2 are good candidates for components of the FRQ-less oscillator and prd-3 and prd-4 act on the system mainly through effects on FRQ/WCC [prd-1,2,3,4] (Mus musculus) PubMed
6143.
Increased iron and hydrogen peroxide concentrations decreased PerR binding to the promoter region of dpr, suggesting that regulation of Dpr by environmental signals is mediated by PerR directly.[PerR] (Mus musculus) PubMed
6144.
nineteen different ms4760 microsatellite profiles of Pfnhe-1 were found including 14 not previously described; multivariate analysis showed no significant association between in vitro susceptibility to quinine with particular ms4760 profiles [Pfnhe-1] (Mus musculus) PubMed
6145.
tryptophan oxygenase cDNA had 1374 nucleotides that encoded a 401 amino acid protein with an estimated molecular mass of 46.47 kDa and a PI of 5.88. [tryptophan oxygenase] (Mus musculus) PubMed
6146.
These findings also identify survivin as a potential new target for the prevention of germ cell death during testicular torsion. (survivin) (Mus musculus) PubMed
6147.
HrtA is responsible for increased expression of immunomodulatory factors and HrtB in absence of HrtA damages bacteria cell membrane by pore formation[HRTA AND HRTB] (Mus musculus) PubMed
6148.
SPL28 encodes a clathrin-associated adaptor protein complex 1, medium subunit micro 1 (AP1M1), which is involved in the post-Golgi trafficking pathway. [SPL28] (Mus musculus) PubMed
6149.
The roles of three actin cytoskeletal proteins, coronin, cofilin and Aip1 in actin dynamics by promoting or regulating disassembly, was examined.[Coronin1, Cofilin1, Aip1] (Mus musculus) PubMed
6150.
The fbl gene was detected in all 17 Staphylococcus lugdunensis isolates examined. (Mus musculus) PubMed
6151.
A naturally occurring missense polymorphism in WRN that interferes with helicase activity abolished its ability to restore top3 phenotype in sgs1 top3 S. cerevisiae.[SGS1; TOP3] (Mus musculus) PubMed
6152.
Influenza A virus NS1 protein serves as a strong inducer of apoptosis in infected human respiratory epithelial cells and plays a critical role in disease pathogenesis.[NS1] (Mus musculus) PubMed
6153.
Endogenous nitric oxide and carbon monoxide and mu3 receptors contribute to morphine-induced ocular hypotension. (mu3 receptor) (Mus musculus) PubMed
6154.
The results of this study suggest for the first time that CYP1A may be implicated in the seawater acclimation of the gills of rainbow trout.[CYP1A] (Mus musculus) PubMed
6155.
Cdc-25 family members function as distinct but related cell cycle regulators to control diverse cell cycles in C. elegans germline development. (Mus musculus) PubMed
6156.
The data provide evidence for the presence of a cation-pi interaction between Arg58 of Ste2p and Tyr(13) of alpha-factor. [Ste2; alpha-factor] (Mus musculus) PubMed
6157.
Activation of AKT and PKBR1 requires PDK1-site phosphorylation, but that phosphorylation by TORC2 is insufficient for AKT or PKBR1 activation.[AKT, PKBR1, PDK1, TORC2] (Mus musculus) PubMed
6158.
the structure of HydA(DeltaEFG) (HydA expressed in a genetic background devoid of the active site H-cluster biosynthetic genes hydE, hydF and hydG) revealing the presence of a [4Fe-4S] cluster and an open pocket for the 2Fe subcluster [HydA] (Mus musculus) PubMed
6159.
the results of studies silencing the expression of Sm-tsp-1 and Sm-tsp-2 mRNAs implied that tetraspanins play important structural roles impacting tegument development, maturation or stability (Mus musculus) PubMed
6160.
results suggest a role for SFL2 in morphogenesis and an indirect role in C. albicans pathogenesis in epithelial tissues (SFL2). (Mus musculus) PubMed
6161.
results suggest that C. albicans PEP12 plays a key role in biofilm integrity and in vivo virulence (PEP12). (Mus musculus) PubMed
6162.
Sum1 functions as a key meiotic brake through the NDT80 promoter and that Cdk1 and Ime2 trigger exit from meiotic prophase by inhibiting the Sum1 transcriptional repression complex.[Cdk1, Ime2, Sum1] (Mus musculus) PubMed
6163.
The authors show that both VP24 and VP40 regulate not only viral genome replication, but also transcription.[VP24 & VP40] (Mus musculus) PubMed
6164.
Intracellular Ca(2+) is a parallel second messenger, by showing that agents that elevate intracellular Ca(2+) levels are potent STATc activators that stimulate phosphorylation of Serine 448 and Serine 747.[STATc] (Mus musculus) PubMed
6165.
Within the intergenic region virA-icsA, a new gene was found that encodes a non-translated antisense RNA, transcribed in cis on the complementary strand of icsA (icsA). (Mus musculus) PubMed
6166.
A homology model was constructed on the basis of the crystal structure of integron integrase VchIntIA from Vibrio cholerae bound to its cognate attC substrate VCRbs.[VchIntIA] (Mus musculus) PubMed
6167.
The DNA bend angle (theta) depends on the TATA sequence, with theta for coreTBP and human TBP being greater than that for yeast TBP.[TBP] (Mus musculus) PubMed
6168.
Assessment of Rot-dependent regulation of target genes revealed that Rot is a positive regulator of spa (protein A) transcription in all strains examined.[Rot] (Mus musculus) PubMed
6169.
This study further established a link between salt and alkali stress and osa-MIR396c in rice.[MIR396c] (Mus musculus) PubMed
6170.
The gene for epidermal cell differentiation inhibitor-B is part of a diverse pathogenicity island present in specific S. aureus clonal lineages. [EDIN-B] (Mus musculus) PubMed
6171.
Sdo1p and SBDS may work to regulate Btn1p and CLN3, respectively (Sdo1p and Btn1p). (Mus musculus) PubMed
6172.
Results suggest that CcCTR1 plays an important role in Cu accumulation in C. cinerea (CcCTR1). (Mus musculus) PubMed
6173.
Esp hinders S. aureus colonization in vivo through a novel mechanism of bacterial interference, which could lead to the development of novel therapeutics to prevent S. aureus colonization and infection [Esp] (Mus musculus) PubMed
6174.
eIF5 stabilizes the binding of GDP to eIF2 and is therefore a bi-functional protein that acts as a GDP dissociation inhibitor (GDI)[eIF5 = TIF5] (Mus musculus) PubMed
6175.
The authors show that F18 associates with an A30-containing multiprotein complex in vivo in a manner that depends upon clusters of hydrophobic/aromatic residues in the N' terminus of the F18 protein.[F18] (Mus musculus) PubMed
6176.
Epstein-Barr virus LMP1-mediated EGFR induction required the NF-kappaB-inducing kinase (NIK) but not the IkappaB kinase (IKK) complex components that regulate canonical or noncanonical NF-kappaB pathways.[LMP1] (Mus musculus) PubMed
6177.
Hfq can form hexamers and to bind RNA molecules, and major role in the survival of Burkholderia cepacia under stress conditions. (Mus musculus) PubMed
6178.
RASCAL and UL50 appeared to specifically interact, suggesting that RASCAL is a new component of the nuclear egress complex (NEC) and possibly involved in mediating nucleocapsid egress from the nucleus.[RASCAL] (Mus musculus) PubMed
6179.
Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) is an essential regulator of calcium-dependent exocytosis in this opportunistic human pathogen [CDPK1] (Mus musculus) PubMed
6180.
Our work demonstrates that although membrane insertion and folding of beta-barrel membrane proteins may be a cooperative process, the fragments can associate in vitro without any additional components.[OmpA] (Mus musculus) PubMed
6181.
The relative contributions of CcrA and CcrB in the excision and integration of staphylococcal cassette chromosome mec(SCCmec).[CcrA; CcrB] (Mus musculus) PubMed
6182.
BcCCC2 is necessary not only for penetrating a host but also for fungal growth within plant tissues [CCC2] (Mus musculus) PubMed
6183.
Mei4 and Rec114, are evolutionarily conserved in most eukaryotes[Mei4] (Mus musculus) PubMed
6184.
These data provide the first evidence that the capacity of the rabies virus P protein to inhibit STAT1 nuclear translocation and interferon signaling correlates with the viral pathogenicity.[P protein] (Mus musculus) PubMed
6185.
The mask of the antigenic epitopes by 158N glycosylation at the HA globular head and its alpha2,3 sialoside binding preference of influenza A/Vietnam/1203/2004 (H5N1) vaccine virus affect virus antigenicity and replication in the host. (Mus musculus) PubMed
6186.
the downstream step in this developmental signaling pathway as a DxDxT phosphatase, TbPIP39, which is activated upon tyrosine phosphorylation, and hence is negatively regulated by TbPTP1 (Mus musculus) PubMed
6187.
The authors conclude that arginines at positions 138, 148, and 150 within the RGG box of ICP27 are required for binding to GC-rich sequences and that the N-terminal portion of ICP27 is highly flexible in structure.[ICP27] (Mus musculus) PubMed
6188.
The D151G substitution was shown to cause a change in the specificity of NA such that it acquired the capacity to bind receptors, which were refractory to enzymatic cleavage, without altering its ability to remove receptors for HA. (Mus musculus) PubMed
6189.
The avian C-terminal ESEV motif of influenza A virus H7N1 NS1 protein increased virulence in mice. (Mus musculus) PubMed
6190.
The authors show that the architecture of the N-terminal domain (NTD) of Nsp1beta adopts a fold closely resembling that of several known nucleases and has intrinsic nuclease activity that is strongly activated by manganese ions.[Nsp1beta] (Mus musculus) PubMed
6191.
This work presents a thorough analysis of the structural, functional and regulatory attributes of PfNapS from P. falciparum with respect to previously studied histone chaperones. (Mus musculus) PubMed
6192.
Molecular and biochemical characterization of two closely related maize 9-lipoxygenase paralogs, ZmLOX4 and ZmLOX5, is reported. [ZmLOX4, ZmLOX5] (Mus musculus) PubMed
6193.
the methyltransferase activity of RlmN and Cfr [RlmN][Cfr] (Mus musculus) PubMed
6194.
Translesion synthesis pathways require Rad8, Mms2 and Ubc13 enzymes needed for poly-ubiquitination of proliferating cell nuclear antigen (PCNA) and for mono-ubiquitination.[Rad8, Mms2 and Ubc13] (Mus musculus) PubMed
6195.
The objectives of this study were to dissect, quantify, and compare the effects of compatible Snn1-SnTox1 and Tsn1-SnToxA interactions on susceptibility in the wheat-S. nodorum pathosystem.[Tsn1, Snn1] (Mus musculus) PubMed
6196.
OsZIP5 plays a role in Zn distribution within rice.[OsZIP5] (Mus musculus) PubMed
6197.
The objectives of this study were to dissect, quantify, and compare the effects of compatible Snn1-SnTox1 and Tsn1-SnToxA interactions on susceptibility in the wheat-S. nodorum pathosystem.[Tox1, ToxA] (Mus musculus) PubMed
6198.
Continuous-wave and pulsed electron paramagnetic resonance spectroscopy have been used to characterize two variants of bacterial sulfite dehydrogenase from Starkeya novella. [SDH] (Mus musculus) PubMed
6199.
Now, we're going to discuss the role of plant PRA concerted with Rab and GDI proteins by recycling Rab between membrane and cytosol for intracellular trafficking of cargo proteins. [OsPRA1] (Mus musculus) PubMed
6200.
A fine-mapping population was used to resolve the Rf2 locus to a 236,219-bp region of chromosome SBI-02.[Rf2] (Mus musculus) PubMed
6201.
The varS gene is involved in regulation of HapA in V. cholerae strain 2740-80. Mutants exhibit decreased HapA production and increased biofilm formation. [VarS; HapA] (Mus musculus) PubMed
6202.
The results indicate that Utp25p is a novel SSU processome subunit involved in pre-40S maturation. (Mus musculus) PubMed
6203.
TbPAR42 is a novel Parvulin anda knockdown of TbPAR42 in its procyclic form results in reduced proliferation rates suggesting an important role in cell growth. [TbPAR42] (Mus musculus) PubMed
6204.
The Aspergillus fumigatus medA deletion mutant exhibited reduced virulence in both an invertebrate and a mammalian model of invasive aspergillosis.[MedA] (Mus musculus) PubMed
6205.
Comparative transcriptome analysis revealed novel roles for the Ras (ras1) and cAMP (cac1) signaling pathways in C. neoformans in both stress response and antifungal drug susceptibility.(ras1 and cac11) (Mus musculus) PubMed
6206.
The up-regulation of miR398a/b and miR408 and the down-regulation of their respective target genes, which encode the copper proteins COX5b and plantacyanin, highlight the involvement of these miRNAs in response to water deprivation in M. truncatula. (Mus musculus) PubMed
6207.
These results suggest that the proper distribution of nucleoids requires the YlmG protein, and the mechanism is conserved between cyanobacteria and chloroplasts.[YlmG] (Mus musculus) PubMed
6208.
XacPNP induces changes in host photosynthesis at the level of protein expression and in photosynthetic efficiency in particular.[XacPNP] (Mus musculus) PubMed
6209.
Murine cytomegalovirus M45-encoded inhibitor of RIP activation (vIRA) targets RIP3 during infection and disrupts RIP3-RIP1 interactions characteristic of TNFalpha-induced necroptosis, thereby suppressing both death pathways.[M45] (Mus musculus) PubMed
6210.
These results indicate that regulation of MAFbx in salmon occurs at both the transcriptional and post-transcriptional level through production of the alternatively spliced MAFbx-beta, which is a likely target for non-sense mediated decay. (MAFbx-beta) (Mus musculus) PubMed
6211.
Three resided in the PB1-F2 open reading frame, caused amino acid (aa) substitutions in the PB1-F2 protein, and reduced A/Vietnam/1203/H5N1 avian influenza virus lethality in mallard ducks. [Pb1-F2] (Mus musculus) PubMed
6212.
a unique DtxR homologue (DR2539) with special characteristics from Deinococcus radiodurans was indentified. (DR2539) (Mus musculus) PubMed
6213.
report cloning of a cDNA (Am5-ht1A) sharing high similarity with members of the 5-HT(1) receptor class; data presented mark first comprehensive study-from gene to behavior-of a 5-HT(1A) receptor in the honeybee [5-HT1A] (Mus musculus) PubMed
6214.
The structure of glycosylated tandem repeats (TR) from Als5 was determined by ab initio modeling. Experiments showed that the hydrophobic TR domains supported binding to polystyrene and other TR domains, leading to nonsaturable homophilic binding.(Als5} (Mus musculus) PubMed
6215.
the Orc1BAH domain was necessary for ORC's stable association with yeast chromosomes, and was physiologically relevant to DNA replication in vivo [Orc1; strain not found] (Mus musculus) PubMed
6216.
demonstrate the direct involvement of H-NS as a positive factor stimulating translation of the malT mRNA [H-NS gene, substrain not found] (Mus musculus) PubMed
6217.
sPLA(2)-III enhances sAPP(alpha) secretion through its action to increase membrane fluidity and recruitment of APP at the cell surface.[sPLA(2)-III] (Mus musculus) PubMed
6218.
The regions 357-368 and 418-427 of HSP60Sp could be associated with glaucoma. [HSP60] (Mus musculus) PubMed
6219.
The expression of surface antigen 6 (CS6) was the most prevalent colonization expressed by enterotoxigenic E. coli in children with diarrhea in Kolkata, India.[CS6] (Mus musculus) PubMed
6220.
data indicate that the assembly of the U4-specific Sm core provides an essential step in U4/U6 di-snRNP biogenesis and splicing in trypanosomes [SSm4] (Mus musculus) PubMed
6221.
Tsh1 encodes a GATA zinc-finger protein and is expressed in the cryptic bract primordium. Mutants fail to suppress bract development. [Tsh1] (Mus musculus) PubMed
6222.
CSA is a key transcriptional regulator for sugar partitioning in rice during male reproductive development. (Mus musculus) PubMed
6223.
MtSNARP1 and MtSNARP2 are members of a novel family of nodulins with RNA-binding activity. [SNARP1; SNARP2] (Mus musculus) PubMed
6224.
under acidic conditions, HP-ferritin was upregulated at pH 5 compared to pH 7; it can switch from an iron-storage protein with ferroxidase activity to a DNA-binding/protection function upon exposure to acidic environment [HP-ferritin] (Mus musculus) PubMed
These results indicate that mutations in the lipid A deacylase PagL which relieve the enzyme from its latency affect the ability of PagL to interact with lipopolysaccharide.(PagL) (Mus musculus) PubMed
6227.
The LATD/NIP gene is a member of the NRT1(PTR) transporter family, and is essential for integrating nutrient and hormone signaling with lateral root growth and nodule development. [LATD] (Mus musculus) PubMed
6228.
UGT73F3 is a uridine diphosphate glycosyltransferase that showed specificity for multiple sapogenins in vitro and was confirmed to be involved in saponin biosynthesis in vivo. [UGT73F3] (Mus musculus) PubMed
6229.
ARS1 and ARS2 are alkylresorcinol synthases that are likely to participate in the biosynthesis of sorgoleone. [ARS1; ARS2] (Mus musculus) PubMed
6230.
Lsi1 plays a role in arsenite efflux in rice roots exposed to arsenate.[Lsi1] (Mus musculus) PubMed
6231.
TehB plays a role in both resistance to oxidative damage and haem uptake and is required for infection in rat models. [tehB] (Mus musculus) PubMed
6232.
Aah and aidA are transcribed as a bicistronic message. [aah, aidA] (Mus musculus) PubMed
6233.
RamA and RamB are involved in the regulation of glycogen synthesis.[RamA and RamB] (Mus musculus) PubMed
6234.
ZmMATE2 expression is not specifically localized to any particular tissue and does not respond to aluminum. [MATE2] (Mus musculus) PubMed
6235.
PM25 is an atypical late embryogenesis-abundant protein that es not interact or stabilize phospholipid membranes in the dry state. [PM25] (Mus musculus) PubMed
6236.
Characterized the zebrafish ortholog of nephrocystin-3 (NPHP3) by morpholino oligo-mediated knockdown. Suggest an essential role in ciliary function. (Mus musculus) PubMed
6237.
didB Delta exacerbates the dominant-negative growth defect resulting from Vps32-GFP over-expression (Did2). (Mus musculus) PubMed
6238.
The first 109 amino acids of DspB/F were required for binding and efficient translocation of DspA/E. [Dspa, DspB, DspF, DspE] (Mus musculus) PubMed
6239.
preliminary characterization of A. nidulans ugeA through analysis of the ugeADelta deletion strain (UgeA). (Mus musculus) PubMed
6240.
ZmFLS1 is a UV-B-inducible maize flavonol synthase. [FLS1] (Mus musculus) PubMed
6241.
RIM1 functions as a regulator of the jasmonate signaling pathway and is degraded by JA treatment via a 26S proteasome-dependent pathway. [RIM1] (Mus musculus) PubMed
6242.
SNF4b plays a role in constitutive defense responses during hydration of dormant seeds. [SNF4b] (Mus musculus) PubMed
6243.
In an in vitro macrophage model of virulence, the sur7Delta mutant was impaired in macrophage killing.[SUR7] (Mus musculus) PubMed
6244.
The phenotypes resulting from Pex2 deletion are no different from those of previously isolated pex mutants affected in peroxisomal protein import, and viable ascospores are produced in selfed crosses.[Pex2] (Mus musculus) PubMed
6245.
The cDNA consisted of 1,700 nucleotides and was predicted to encode a 474-amino acid protein.[CitA] (Mus musculus) PubMed
6246.
The results indicated that the BIR or RING motif of Antheraea pernyi nucleopolyhedrovirus inhibitor of apoptosis protein1 (IAP1) had equally function to inhibit cell apoptosis.[IAP1] (Mus musculus) PubMed
6247.
findings show Ssp1 and Ssp2 are structurally similar to fucose-specific lectins and suggest regulatory compensation for loss of Ssp1 coupled with potential functional redundancy among lectins accumulating in sclerotia and apothecia [Ssp1, Ssp2] (Mus musculus) PubMed
6248.
[nAChR alpha7] nAChR alpha3 and alpha7 lateral mobility is controlled by domain specific, receptor subtype dependent, and cell-type constrained mechanisms; this system could tailor nicotinic signaling capabilities to specific needs of individual locations (Mus musculus) PubMed
6249.
We conclude increased resistance to host cathelicidin and killing within phagocyte extracellular traps contribute to the propensity of M1 GAS strains to produce invasive infections. [M1 protein] (Mus musculus) PubMed
6250.
These findings suggest that NAD(+) glycohydrolase has a NADase-independent function and prompt a reevaluation of its role in streptococcal pathogenesis. (Mus musculus) PubMed
6251.
Taken together, the data suggest a model for occlusion in which A26p has a bridging role between ATIp and A27p, and A27p provides a link to the mature virion membrane.[ATI, A26 & A27] (Mus musculus) PubMed
6252.
The authors identified the putative pocket protein binding sequence (PPBS) on C42 that is essential for C42 to exert its function in nuclear actin polymerization.[C42] (Mus musculus) PubMed
6253.
The function of quorum-sensing E. coli regulator D (QseD) in enterohemorrhagic E. coli and E. Coli K12 is reported.[QseD] (Mus musculus) PubMed
6254.
nphT7, found in the mevalonate pathway gene cluster from a soil-isolated Streptomyces sp. strain, encodes an unusual acetoacetyl-CoA synthesizing enzyme [nphT7] (Mus musculus) PubMed
6255.
Pom33 (YLL023C), is an evolutionarily conserved membrane protein that is functionally linked to nuclear pore complexes (NPC) components and required for proper NPC assembly and/or stability in S. cerevisiae [pom33] (Mus musculus) PubMed
6256.
Loss-of-function mutants of PALM1 develop dissected leaves with five leaflets clustered at the tip.[PALM1] (Mus musculus) PubMed
6257.
HP0256 is required for full motility and it is involved, possibly indirectly, in expression of outer membrane proteins and adhesins involved in pathogenesis and adhesion.[HP0256] (Mus musculus) PubMed
6258.
crystals of MglA belonged to the hexagonal space group P6(1) or P6(5), with unit-cell parameters a = b = 125, c = 54 A.[MglA] (Mus musculus) PubMed
6259.
crystals of HPPK belonged to space group P2(1), with unit-cell parameters a = 36.8, b = 76.6, c = 51.5 A, alpha = gamma = 90.0, beta = 100.2 degrees.[6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK)] (Mus musculus) PubMed
6260.
crystal structures of Saccharomyces cerevisiae Poleta (also known as RAD30) in ternary complex with a cis-syn thymine-thymine (T-T) dimer and with undamaged DNA [RAD30] (Mus musculus) PubMed
6261.
Cytomegalovirus pUL83 recruits human IFI16 to the major immediate-early promoter, and IFI16 binding at the promoter is dependent upon the presence of pUL83.[pUL83] (Mus musculus) PubMed
6262.
Staphylococcal pathogenicity island derepression is effected by a specific, non-essential phage protein (dut) that binds to Stl, disrupting the Stl-DNA complex and thereby initiating the excision-replication-packaging cycle of the island [dut=dUTPase] (Mus musculus) PubMed
6263.
These data show that, in addition to directly driving the transcription of the dinB gene in stationary-phase cells, RpoS regulates the activity of Pol IV in exponentially growing cells via a second, indirect pathway.[RpoS; DinB] (Mus musculus) PubMed
6264.
Plasmodium actin-depolymerization factors 1 and 2 have been crystallized. The crystals diffracted X-rays to maximum resolutions of 2.0 and 2.1 A.[actin-depolymerization factor 1 and actin-depolymerization factor 2] (Mus musculus) PubMed
6265.
Plasmodium actin-depolymerization factors 1 and 2 have been crystallized. The crystals diffracted X-rays to maximum resolutions of 2.0 and 2.1 A.[actin-depolymerization factor 1 and actin-depolymerization factor 2] (Mus musculus) PubMed
6266.
Native and SeMet-derivative crystals of D/C mosaic neurotoxin showed X-ray diffraction to 2.8 and 3.1 A resolution, respectively. [botulinum toxin type C and botulinum toxin type D] (Mus musculus) PubMed
6267.
Staphylococcal pathogenicity island derepression is effected by a specific, non-essential phage protein (dut) that binds to Stl, disrupting the Stl-DNA complex and thereby initiating the excision-replication-packaging cycle of the island [dut=dUTPase] (Mus musculus) PubMed
6268.
SeDsbA, SeDsbL and SeSrgA crystals diffracted to resolution limits of 1.55, 1.57 and 2.6 A and belonged to space groups P2(1), P2(1)2(1)2 and C2, respectively.[DsbL] (Mus musculus) PubMed
6269.
Our results showed that functional deficiency due to frameshift mutation and subsequent nonsense mutation in perA reduced BFP expression in typical EPEC strains isolated in Japan.[perA, BfpA] (Mus musculus) PubMed
6270.
Structures of Nup145N residues 443-605 [Nup145N(443-605)] from the larger autoproteolytic segment, are described.[Nup145] (Mus musculus) PubMed
6271.
The authors demonstrate that that two DNA replication proteins are substrates of Pfmrk-mediated phosphorylation and that PfMAT1 confers substrate specificity to the Pfmrk kinase complex.[Pfmrk & PfMAT1] (Mus musculus) PubMed
6272.
study shows highly dynamic regulation of Crmp-2 forms during development and identifies post-translational changes in Crmp-2 as putative contributors to the maintenance of spinal-cord regenerative ability [Crmp-2] (Mus musculus) PubMed
6273.
Rice with Xa7 exhibited less disease than lines without Xa7 over 11 yr, even though virulence of Xoo field populations increased. Xa7 restricted disease more effectively at high than at low temperatures. [Xa7] (Mus musculus) PubMed
6274.
The effects of secG and secY2 mutations in the extracellular proteome biogenesis of S. aureus are reported; the effects of mutations on organism virulence are included.[secG; sexY2] (Mus musculus) PubMed
6275.
These results indicate that NADase is important for the virulence of Streptococcus pyogenes in vivo and is the potential target to suppress the virulence.[NADase] (Mus musculus) PubMed
6276.
The interactions of Poly(A) polymerase I (PAP I) with multiple rpoteins in the RNA degradosome, and the role of RssB in its maintenance are reporte.[RssB; PAP I] (Mus musculus) PubMed
6277.
study demonstrated significant in vitro activities and multifaceted specificities of protein arginine methyltransferases (PRMTs) and provided evidence for a role of protein methylation in mechanisms of oxidative stress response [RmtA,RmtB,RmtC] (Mus musculus) PubMed
6278.
It was also shown that the CH domains are functional and bind to F-actin, whereas the BAR and GBD/FH3 domains interact in vitro and in vivo with different families of GTPases such as Rho and Ras, and with different phosphoinositides.[EhNCABP166] (Mus musculus) PubMed
6279.
The structure of GlgX from Escherichia Coli K12 was determined at 2.25 A resolution.[GlgX] (Mus musculus) PubMed
6280.
Lis1, nuclear migration protein, controls microtubule dynamics and thus the regulated delivery of vesicles to growth sites and other cell domains that govern nuclear movements.[Lis1] (Mus musculus) PubMed
6281.
roles of both cytoplasmic N and C termini in channel assembly and stability of KcsA were determined.[KcsA] (Mus musculus) PubMed
6282.
both JBP2 and JBP1 are capable of stimulating de novo base J-synthesis (JBP1 and JBP2). (Mus musculus) PubMed
6283.
Alpha-phosphoglucomutase isozymes were characterized and the data indicated that TgPGM-I, but not TgPGM-II, may play an important role in alpha-D-glucose 6-phosphate production. [PGM-I, PGM-II] (Mus musculus) PubMed
6284.
The authors demonstrate that VrrA RNA represses ompT translation by base-pairing with the 5' region of the mRNA and that regulation requires the RNA chaperone protein Hfq.[VrrA, OmpT, Hfq] (Mus musculus) PubMed
6285.
This study reports a high-resolution NMR structure for full-length myristoylated yeast (Saccharomyces cerevisiae) Arf1 in complex with a membrane mimic. [Arf1] (Mus musculus) PubMed
6286.
This study shows formation of large inverted chromosome duplications at the site of a 246 bp interrupted DNA palindrome in the absence of the SbcCD and the RecA.[SbcC, SbcD, RecA] (Mus musculus) PubMed
6287.
CvfB represents a novel assembly of modules for binding RNA [CvfB] (Mus musculus) PubMed
6288.
structural insights into sialyl transfer by the trans-sialidase (Mus musculus) PubMed
6289.
AbsB and AdpA participate in a post-transcriptional regulatory loop that modulates the cellular levels of the proteins encoded by both genes (AbsB and AdpA). (Mus musculus) PubMed
6290.
The N-terminal 107 residues of ColA (TA1-107) bound to TolB to show that the TolB box of ColA consists of a 12-residue domain that binds to the beta-propeller canyon of TolB (ColA). (Mus musculus) PubMed
6291.
These studies suggest that besides the conserved helicase domain of the novel DEAD box helicase Has1p,the highly variable N-terminal region also contributes in the activity of the protein. [Has1p] (Mus musculus) PubMed
6292.
Mutagenesis studies support that the proline-induced structural twist contributes directly to gyrase's (-) supercoiling activity (gyrase A subunit). (Mus musculus) PubMed
6293.
Streptolysin O mutants that are unable to form pores retain the ability to translocate nicotinamide adenine dinucleotide-glycohydrolase.[Streptolysin O] (Mus musculus) PubMed
6294.
A model for EhC2A-mediated regulation of the transcriptional activities of URE3-BP via Ca(2+)-dependent anchoring of the transcription factor to the amebic plasma membrane, is proposed.[URE3-BP, EhC2A] (Mus musculus) PubMed
6295.
sporozoite latency is an active process controlled by a eukaryotic initiation factor-2alpha (eIF2alpha) kinase (IK2) and a phosphatase.[IK2] (Mus musculus) PubMed
6296.
Septum-associated microtubule-organizing centers share at least two further components, gamma-tubulin and GcpC (S. pombe Alp6) with spindle pole bodies and ApsB interacts with gamma-tubulin.[ApsB, gamma tubulin] (Mus musculus) PubMed
6297.
These results show that enteropathogenic Escherichia coli effector NleH acts via a global anti-apoptotic pathway.[NleH] (Mus musculus) PubMed
6298.
Study demonstrates that SCO5725 (EsxA) and SCO5724 (EsxB) in S. coelicolor are novel morphogenetic proteins whose secretion is dependent on functions encoded by at least two other genes in the locus.[EsxA, EsxB] (Mus musculus) PubMed
6299.
Based on its cell-division-dependent localization and interaction with FtsZ, study proposes that StkP plays a currently undefined role in cell division of pneumococcus.[StkP] (Mus musculus) PubMed
6300.
The authors provide evidence that the aryl alcohol dehydrogenase NorA (AflE) encoded by the aflatoxin biosynthetic gene cluster in Aspergillus flavus affects the accumulation of aflatoxins in the final steps of aflatoxin biosynthesis.[NorA] (Mus musculus) PubMed
6301.
Using in vivo and in vitro binding assays, study showed that this motif anchors the SciZ protein to the cell wall and is required for Type VI secretion systems function.[SciZ] (Mus musculus) PubMed
6302.
OmpC is compared to its structural homolog OmpF at different KCl concentrations, pH values, and a broad temperature range. [OmpC][OmpF] (Mus musculus) PubMed
6303.
insight into the molecular basis for the distinct functional properties of OmpU and OmpT proteins [OmpU][OmpT] (Mus musculus) PubMed
6304.
The membrane topology of a recently recognized Gtr, GtrIc, which is known to mediate S. flenxeri serotype switching from 1a to 1c, is presented.[GtrIc] (Mus musculus) PubMed
6305.
Sclerotinia sclerotiorum agglutinin reveals a novel dimeric assembly markedly dissimilar to those described earlier for ricin-type lectins.[Sclerotinia sclerotiorum agglutinin] (Mus musculus) PubMed
6306.
P-TEFb is recruited to the promoter in a catalytically inactive state bound to the inhibitory 7SK small nuclear ribonucleoprotein (snRNP), thereby preventing elongation.[small nuclear ribonucleoprotein] (Mus musculus) PubMed
6307.
the role of Tlp1 as a chemoreceptor was investigated using isogenic mutants and through analysis of protein-protein interactions with the predicted chemotaxis proteins of C. jejuni NCTC 11168 using the yeast hybrid systems (Tlp1). (Mus musculus) PubMed
6308.
TbPLK has accomplished its role in guiding cytokinesis before the late S phase, presumably by phosphorylating a certain substrate(s) during S phase, which may play a critical role in initiating the subsequent cytokinesis.[TbPLK] (Mus musculus) PubMed
6309.
This work shows that the sigma(R)-RsrA system plays a more significant role in protein quality control than previously realized, and emphasizes the importance of controlling the cellular thiol-disulphide redox balance.[sigR] (Mus musculus) PubMed
6310.
This is the first molecular dynamic study that simulates the whole tetrameric catalase structure immersed in water and in a H2O2 solution. [catalase-1] (Mus musculus) PubMed
6311.
The authors show that in Schizosaccharomyces pombe, mating-specific cell adhesion is dependent on the exocyst subunit Sec8p, but independent of the exocyst subunit Exo70p.[Sec8p & Exo70p] (Mus musculus) PubMed
6312.
In this study, three Panton-Valentine Leukocidin gene carrying methicillin-susceptible Staphylococcus aureus (MSSA) strains (M1-AAG42B, PY30C-b and YF1B-b) were isolated from different food samples in Kesan-Edirne, Turkey. (Mus musculus) PubMed
6313.
the critical role of RAD51 in controlling the balance between targeted and random integration events observed upon transgenesis [RAD51] (Mus musculus) PubMed
6314.
A focal gradient of MAG can induce polarized endocytosis with asymmetric redistribution of beta1-integrin and vinculin-containing contact adhesions in axonal growth cones (MAG, myelin-associated glycoprotein) (Mus musculus) PubMed
6315.
The authors found a strong correlation between the macroscopic translocation rates and the binding affinity of the translocating NS3h protein for the respective substrates such that weaker affinity corresponded to faster translocation.[NS3] (Mus musculus) PubMed
6316.
Nitroreductase NRSal from Salmonella typhimurium is a versatile biocatalyst that displays both nitroreductase and enoate reductase activity.[nitroreductase] (Mus musculus) PubMed
6317.
The TaNIP gene codes for an aquaporin that markedly improved salt tolerance of transgenic Arabidopsis plants. [NIP] (Mus musculus) PubMed
6318.
structure of urate oxidase was refined at atomic resolution (1 A) using new crystal data in the presence of xanthine and at near-atomic resolution (1.3-1.7 A) in complexes with the natural substrate (urate) [ urate oxidase ] (Mus musculus) PubMed
6319.
The data presented constitutes a targeted analysis of the formation of the GtrV active site and highlights the essential role of the large periplasmic Loop 2 in its function.[GtrV] (Mus musculus) PubMed
6320.
These data provide a causal link between changes in the J protein partner and specialization of duplicate Hsp70.[Jac1, Hsp70] (Mus musculus) PubMed
6321.
S. cerevisiae thr1Delta and thr4Delta mutants were severely depleted after only 4 h in vivo. Similarly, Candida albicans thr1Delta mutants, but not hom3Delta mutants, were significantly attenuated in virulence.[Homoserine kinase] (Mus musculus) PubMed
6322.
Results strongly indicate that the main function of HmuP is the transcriptional regulation of shmR.[HmuP] (Mus musculus) PubMed
6323.
Neurospora cry encodes a DASH-type cryptochrome that appears capable of binding flavin adenine dinucleotide (FAD) and methenyltetrahydrofolate (MTHF). [Cryptochrome] (Mus musculus) PubMed
6324.
Delayed re-endothelialization with rapamycin-coated stents is rescued by the addition of a glycogen synthase kinase-3beta inhibitor. (Mus musculus) PubMed
6325.
a different, but also effective, electron-transfer cascade is conserved among the class II photolyases [class II cyclobutane pyrimidine dimer photolyases] (Mus musculus) PubMed
6326.
TgSPATR (secreted protein with an altered thrombospondin repeat) of Toxoplasma gondii (TgSPATR), is probably new member of microneme protein and maybe involved in parasite invasion. [TgSPATR] (Mus musculus) PubMed
6327.
The study reports the first crystal structure of a DEAH/RHA helicase: the full-length yeast Prp43 in complex with ADP/Mg2+ at 1.9 A resolution.[Prp43] (Mus musculus) PubMed
6328.
analysis of the humoral immune response against the prokaryotic expressed N-terminal autoprotease (N(pro)) protein of bovine viral diarrhoea virus [N(pro)] (Mus musculus) PubMed
6329.
NOPP44/46 is a major substrate of TbPTP1.[TbPTP1, NOPP44/46] (Mus musculus) PubMed
6330.
HBV/P22 protein could inhibit the induced apoptosis of HepG2 cells both in vitro and in vivo. [p22] (Mus musculus) PubMed
6331.
Strains expressing EibG-alpha and EibG-beta displayed a mostly typical chain-like adherence pattern (CLAP), with formation of long chains on both human and bovine intestinal epithelial cells. (Mus musculus) PubMed
6332.
Expression of the NS1 proteins resulted in inhibition of host innate immune responses (beta interferon and protein kinase R production).[NS1] (Mus musculus) PubMed
6333.
The authors demonstrated that the LuxS/AI-2 signaling system regulates capsular polysaccharide production via a two-component system, KdpDE, whose function has not yet been clarified in Staphylococcus aureus.[KdpE] (Mus musculus) PubMed
6334.
An R217A substitution in the J domain-interacting surface of BiP compromised the physical and functional interaction with Sec63p, an Hsp40 required for Eendoplasmic reticulum translocation.[BiP] (Mus musculus) PubMed
6335.
These results not only provide evidence that mRNA unwinding by eIF4A stimulates start codon recognition, but also suggest that the eIF4A-binding site on eIF4G made of the HEAT domain stimulates the ribosomal scanning independent of eIF4A.[eIF4A, eIF4G] (Mus musculus) PubMed
6336.
Imidazole binding to cyt c(1) substantially lowers the midpoint potential of the heme and fully inhibits bc(1) complex activity.[Cytochrome c1] (Mus musculus) PubMed
6337.
The kinetics of imidazole (Im) and N-methylimidazole (MeIm) binding to oxidized cytochrome (cyt) c(1) of detergent-solubilized bc(1) complex from Rhodobacter sphaeroides are described.[Cytochrome c1] (Mus musculus) PubMed
6338.
TGF-beta1 modulates the expression of IGFBP-4 and PAPP-A in cultured periosteal explants.[PAPP-A, rabbit; and IGFBP-4, rabbit] (Mus musculus) PubMed
6339.
The results suggest evolutionary adaptation of ASIC1 to match the value of the species-specific plasma pH.[ASIC1] (Mus musculus) PubMed
6340.
These results suggest that EDIN is a risk factor for Staphylococcus aureus dissemination through the vasculature by virtue of its ability to promote the formation of infection foci in deep-seated tissues.[EDIN] (Mus musculus) PubMed
6341.
Rab5 and Rab7, were associated with the pathway of autophagosome formation and the fate of intracellular group A streptococcus. (Mus musculus) PubMed
6342.
These data place Isd11 at the center of these sulfur transactions and raises the possibility of a connection between Fe/S metabolism and protein synthesis, helping integrate two seemingly unrelated pathways.[Isd11] (Mus musculus) PubMed
6343.
results demonstrate the involvement of Pbr on the regulation of phenazine biosynthesis, and an important role for this regulatory protein on several cellular processes related to stress resistance and virulence[Pbr] (Mus musculus) PubMed
6344.
T. gondii PBGS displays a broad activity peak (pH 7-8.5), with a K(m) for aminolevulinic acid of approximately 150 microM and specific activity of approximately 24 micromol of porphobilinogen/mg of protein/h.[PBGS] (Mus musculus) PubMed
6345.
These results show that the H274Y NA mutation affects the fitness of two H5N1 influenza viruses differently. (Mus musculus) PubMed
6346.
The authors report that CD2AP, an endocytosis-associated and cortactin-binding protein, is a novel and important component of enteropathogenic Escherichia coli pedestal formation that also utilizes Y474 phosphorylation of the bacterial Tir.[Tir] (Mus musculus) PubMed
6347.
Seven mutants showed notable abnormalities in processing (constructs with the E1231A, E1249A, and R1374A mutations) and beta-barrel assembly or insertion into the outer membrane (constructs with the G1158Y, F1360A, Y1375A, and F1377A mutations).[EspP] (Mus musculus) PubMed
6348.
By introducing the M112/M113 mutations into wt murine cytomegalovirus, the authors demonstrated that they are sufficient to facilitate murine cytomegalovirus replication in human cells.[M113] (Mus musculus) PubMed
6349.
These results suggest that Epidermal Growth Factor (EGF)-like Cyst Protein 1(EGFCP1)s may function like cyst wall proteins, involved in differentiation of Giardia lamblia trophozoites into cysts.[EGFCP1] (Mus musculus) PubMed
6350.
These data suggest that HpHSP60 enhances angiogenesis via CXCR2/PLCbeta2/Ca2+ signal transduction in endothelial cells.(HSP60) (Mus musculus) PubMed
6351.
Data suggest that there are three factors that govern nucleoprotein oligomerization: interaction between the tail loop and the insertion groove, maintenance of the tail loop conformation, and stabilization of the NP homo-oligomer [H1N1 NP] (Mus musculus) PubMed
6352.
Data show that OrfA acts to markedly reduce cell surface expression of the FIV primary binding receptor, CD134. (Mus musculus) PubMed
6353.
The authors present evidence that CadC negatively regulates the expression of the arginine-dependent adaptive acid-resistance system (AR3), encoded by the adi locus while it has no effect on the expression of AR1 and AR2 systems.[CadC] (Mus musculus) PubMed
6354.
results suggest a role for SkzL in S. agalactiae pathogenesis through fibrinolytic enhancement [Skzl] (Mus musculus) PubMed
6355.
analysis of interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46 [IFT46] (Mus musculus) PubMed
6356.
These findings strongly implicate steric hindrance as the mechanism of repression of rob by MarA.[marA; rob] (Mus musculus) PubMed
6357.
These results explain the inhomogeneous distribution of OmpR in and demonstrate that binding to native sites in the chromosome can be imaged and quantified by fluorescence microscopy.[OmpR] (Mus musculus) PubMed
6358.
The effects of site-directed mutagenesis on the export and metabolism of cytolysin A, a cytolytic pore-forming toxin, are reported.[ClyA] (Mus musculus) PubMed
6359.
Cln3 is involved in the mechanism underlying sporulation incompetence by inhibiting IME1 transcription and the Ime1-Ume6 interaction [strain Kyokai no 7 (K7); genes: Cln3, IME1, Ume6] (Mus musculus) PubMed
6360.
This study show that when E. coli's origin of replication is substituted by V. Cholerae oriCI, dam, but not seqA, becomes important for growth, arguing that Dam methylation exerts a critical function at the origin of replication.[dam] (Mus musculus) PubMed
Promoter of penicillin biosynthesis genes pcbC gene didn't contain TATA box-like sequence but pcbAB and penDE contain proposed TATA boxes. [pcbC, pcbAB and penDE] (Mus musculus) PubMed
6363.
identify the catalytic and coenzyme binding domains of L-arabinitol 4-dehydrogenase (LAD1) from Hypocrea jecorina [LAD1]. (Mus musculus) PubMed
6364.
Findings provide evidence that gamma-glutamyl transpeptidase (GGT) is a pathogenic factor associated with H pylori-induced peptic ulcer disease. (Mus musculus) PubMed
6365.
These data suggest that RssAB signaling negatively regulates prodigiosin production, and such inhibition is mediated through direct and specific repression of transcriptional activity of the pig operon.[RssA, RssB, PigA] (Mus musculus) PubMed
6366.
The data show that Plasmodium falciparum PFE0485w can functionally complement a Saccharomyces cerevisiae temperature-sensitive pik1 mutation.[pik1] (Mus musculus) PubMed
6367.
Mouse antiserum raised against recombinant KPA3 recognized a 21.8kDa protein, which was found, by indirect immunofluorescence and immunoelectron microscopy, to be associated with the Trypanosoma cruzi kinetoplast.[KAP3] (Mus musculus) PubMed
6368.
Host membrane phosphatidylserine plays a key role in the delivery, localization, and pathophysiological action of CagA. (Mus musculus) PubMed
6369.
This study used bioinformatic and statistical analyses to evaluate whether the allelic diversity of the outer membrane proteins homB and homA is generated by recombination.[homA; homB] (Mus musculus) PubMed
6370.
The analysis of chromosomal segregation in smc (structural maintenance of chromosomes) and spoIIIE single and double mutants unravels differences in the chromosome dynamics in the spherical staphylococcal cells compared to the model in rods.[SMC; SpoIIIE] (Mus musculus) PubMed
6371.
crystal structure of KcsA in its open-inactivated conformation and investigation of the mechanism of C-type inactivation gating at the selectivity filter from channels 'trapped' in a series of partially open conformations [KcsA] (Mus musculus) PubMed
6372.
side-chain rearrangements at position 103 mechanically couple activation and inactivation in KcsA [KcsA] (Mus musculus) PubMed
6373.
Simulations of diffusion and exchange of GFP-Ras2 between the membrane and cytosol show that the spatial dependence of fluorescence recovery after photobleaching curves can be used to account for exchange if it occurs.[Ras2] (Mus musculus) PubMed
6374.
Cdc13 can bind to the telomeric template for lagging-strand replication.[Cdc13] (Mus musculus) PubMed
6375.
Ecm29 functions as scaffold protein during the remodeling of incompletely matured RP-CP assemblies into regular enzymes. [Ecm29] (Mus musculus) PubMed
6376.
Expansion of the target of rapamycin (TOR) kinase family and function shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity. (TOR3) (Mus musculus) PubMed
6377.
Data highlight a potential human adaptation of NS1 that seems absent in "classically derived" swine-origin influenza A viruses, including the 2009 H1N1 virus[NS1] (Mus musculus) PubMed
6378.
TCRR-1 and TCRR-2 encode type-A response regulators whose expression is cell type specific and developmentally regulated. (Mus musculus) PubMed
6379.
Oryza sativa Rac1 is activated by Pit during pathogen attack and plays a critical role in Pit-mediated immunity in rice.[Rac1 & Pit] (Mus musculus) PubMed
6380.
This study indicates a possible role for AdhC in aldehyde metabolism and a broader role for NmlR(sp) in the regulation of carbon metabolism.[NmlR(sp)] (Mus musculus) PubMed
6381.
The roles of the pca gene in carbon dioxide metabolism and growth of S. pneumoniae under carbon dioxide-poor conditions are reported.[pca] (Mus musculus) PubMed
6382.
Data show that human Daxx-mediated repression of LUNA during lytic infection absolutely requires IE72 gene expression[IE72] (Mus musculus) PubMed
6383.
The putative virulence factor C protein beta was found to be upregulated under the conditions hypothesised to reflect those associated with foetal exposure to Streptococcus agalactiae.[C protein beta] (Mus musculus) PubMed
6384.
Targeted disruption of the pkrp gene in Plasmodium berghei, a rodent model of malaria, compromises the ability of parasites to infect different tissues within the mosquito host.[pkrp] (Mus musculus) PubMed
6385.
Data suggest that PKA signalling is required for cercarial viability and may play a specific role in the reproductive activity of adult Schistosoma mansoni worms.[protein kinase A] (Mus musculus) PubMed
6386.
These observations suggest that glutamine synthase is essential to NH(4)(+) repression of nitrogenase and that deletion of glnA1 results in the complete derepression of nitrogenase by preventing NH(4)(+) assimilation in vivo.[glnA1] (Mus musculus) PubMed
6387.
the role of the unscheduled meiotic gene expression 6 (UME6) gene in Kluyveromyces lactis (Mus musculus) PubMed
6388.
genetic and biochemical evidence that the Lon protease and the SecB and DnaJ/Hsp40 chaperones are involved in the quality control of presecretory proteins in Escherichia coli. [Lon protease][SecB][DnaJ] (Mus musculus) PubMed
6389.
ArcAB two-component system of S. enterica stimulates pSLT transfer under microaerobiosis by two concerted actions: activation of the tra operon and repression of the sdhCDAB operon.[ArcA][ArcB][SdhA][SdhB][SdhC][SdhD] (Mus musculus) PubMed
6390.
Accumulation of sorghum 3-deoxyanthocyanidin phytoalexins and resistance to C. sublineolum in sorghum require a functional y1 gene. (Mus musculus) PubMed
6391.
Cop6, a sesquiterpene synthase, is a "high-fidelity" alpha-cuprenene synthase that retains its fidelity under various conditions tested.[Cop4, Cop6] (Mus musculus) PubMed
6392.
CagL may contribute directly to H. pylori pathogenesis by promoting aberrant signaling cross-talk within host cells. (Mus musculus) PubMed
6393.
UmuD(2), when bound to DinB, displaces the equilibrium in favor of the non-slipped conformation, thereby preventing frameshifting and potentially enhancing DinB activity on non-slipped substrates[DinB & UmuD] (Mus musculus) PubMed
6394.
our data reveal the existence of a cross-talk between the canonical Wnt pathway and the Sir2-FoxO longevity pathway to protect against mutant PABPN1 toxicity [PABPN1] (Mus musculus) PubMed
6395.
identified 32 transgene-positive zebrafish, transmitting one or more independent constructs displaying ASCL1-like regulatory control. [ASCL1] (Mus musculus) PubMed
6396.
solid-state NMR chemical shift fingerprints of two distinct conformations of the selectivity filter; changes are observed in the chemical shifts of key residues in the filter as the potassium ion concentration is changed from 50 mM to 1 muM (KcsA channel) (Mus musculus) PubMed
6397.
Data show that the florigen gene Hd3a (Heading date 3a) is toggled by only a 30-min day-length reduction: [Hd3a] (Mus musculus) PubMed
6398.
Using U373MG cells we found that IE86 protein was bound to cellular Mcm3, but did not inhibit the cellular DNA synthesis. (IE86) (Mus musculus) PubMed
6399.
identification of the protease responsible for proteolytic cleavage ta C-terminus of SAGA complex and generation of SLIK protein complex [Pep4p] (Mus musculus) PubMed
6400.
ACO1 has a little effect on internode elongation at the heading stage. [ACO1] (Mus musculus) PubMed
6401.
it appears that cryptochrome 1 has significant spectroscopic and electrochemical similarities to Escherichia coli DNA photolyase. (Mus musculus) PubMed
6402.
The structures of the apoenzyme and the reaction intermediate (pantoyl adenylate; PA) complex were determined by X-ray crystallographY [pantothenate synthetase] (Mus musculus) PubMed
6403.
information on the ability of RNase BN to process tRNA precursors [RNase BN] (Mus musculus) PubMed
6404.
Dmr1p is therefore the first yeast pentatricopeptide repeat protein, which has an rRNA target and is probably involved in the biogenesis of mitochondrial ribosomes and translation.[DMR1] (Mus musculus) PubMed
6405.
The expression of II type collagen and MMP-7 is correlated to a retrogression of acetabular cartilage and increases obviously in early developmental dysplasia. (Mus musculus) PubMed
6406.
These results indicated that Plasmodium ADF2 plays a pivotal role in transformation in the malaria parasite life cycle.[ADP2] (Mus musculus) PubMed
6407.
report the identification of Dbx1 as a direct target of Gsh2-mediated transcriptional repression, and show that a series of cross-repressive interactions[Gsh2] (Mus musculus) PubMed
6408.
OsRZ2 complements the defect in mRNA export from the nucleus to the cytoplasm in grp7 mutant plants during cold stress. [RZ2] (Mus musculus) PubMed
6409.
These results raise the possibility that the activity of AphB is influenced by the pH and oxygen tension of the environment.[AphB] (Mus musculus) PubMed
6410.
the high-resolution crystal structures of substrate-loaded Asp105Asn and His88Gln mutants of Synechocystis sp. PCC 6803 PcyA in the initial oxidized and one-electron reduced radical states were reported.(PcyA) (Mus musculus) PubMed
6411.
The identification and functional characterisation of the eroA and ervA genes from Aspergillus niger, is described.[eroA, ervA] (Mus musculus) PubMed
6412.
The combined results suggest a unique mechanism that ensures the transport of a single substrate by the SecA2/Y2 system.[SecA2 & SecY2] (Mus musculus) PubMed
6413.
Results of the present study indicate that the FecL(L) mutation could act on the ovaries by modulating follicular development and by modulating, indirectly or directly. (FecL(L)) endocrine profiles [FecL] (Mus musculus) PubMed
6414.
AggR regulates its own expression in mammalian intestind during EAEC infection. [AggR] (Mus musculus) PubMed
6415.
a putative role in autoregulation of nodulation; linked to proliferation and differentiation [CLE12, CLE13] (Mus musculus) PubMed
6416.
Studies show that the 1.9-A resolution crystal structure of the basal pilin FctB, revealing an immunoglobulin (Ig)-like N-terminal domain with an extended proline-rich tail: [ pilin FctB] (Mus musculus) PubMed
6417.
Our data suggest that a neuromeddin U receptor (nmur-1) processes information from specific food cues to influence lifespan and other aspects of physiology. (Mus musculus) PubMed
6418.
MADD-2 is a UNC-40 cofactor in axon attraction and branching, paralleling the role of UNC-5 in repulsion;, targeting of a guidance factor to specific axonal branches can confer differential responsiveness to guidance cues.(MADD-2 PROTEIN, C ELEGANS) (Mus musculus) PubMed
6419.
Our results suggest that MADD-2 may enhance UNC-40 pathway activity by facilitating an interaction between UNC-40 and UNC-73(MADD-2 PROTEIN, C ELEGANS) (Mus musculus) PubMed
6420.
RecQ helicase might act on the DNA structures that are generated by the processing of DNA by the MutSLH complex and UvrD helicase.[RecQ, RecJ, MutS, UvrD] (Mus musculus) PubMed
6421.
We have identified the transcription factor Tec1 as the last component of the newly evolved signal transduction pathway that regulates the pheromone response of the white cell phenotype in Candida albicans. [Tec1] (Mus musculus) PubMed
6422.
the differences among the P. vivax circumsporozoite protein variants are restrict to the central repeated region of the protein, mostly nucleotide variation with important serological consequences [circumsporozoite protein, p vivax] (Mus musculus) PubMed
6423.
Findings suggest that p13 may have a distinct impact on T cell turnover depending on the inherent ROS level: [p13] (Mus musculus) PubMed
6424.
Expression of MYBS3 is ubiquitous and is activated by cold stress. It suppresses the DREB1-dependent pathway under prolonged cold stress. [MYBS3; DREB1] (Mus musculus) PubMed
6425.
ETA gene was transferred by three phages into non-toxigenic S. aureus strains responsible for outbreaks of pemphigus neonatorum in the Czech Republic. [ETA] (Mus musculus) PubMed
6426.
Study determined the crystal structure of Galactitol 2-dehydrogenase (GatDH) in complex with its cofactor NAD(H) and three different substrates from Rhodobacter sphaeroides strain D: [GatDH] (Mus musculus) PubMed
6427.
Differential expression of CYP51, 14-SR as well as C4MO would contribute to the MAS synthesis and metabolism in response to gonadotropins in the rabbit ovary and testis.[CYP51][14-SR][C4MO] (Mus musculus) PubMed
6428.
observe synthetic-negative interactions between mutations in the switch loop of RF1 and in helix 69 of 23S rRNA, revealing that these structural features interact functionally in the termination process.[release factor 1] (Mus musculus) PubMed
6429.
CymR plays a major role in virulence and adaptation of S. aureus for survival within the host (Mus musculus) PubMed
6430.
The thylakoid phosphoproteome of the wild-type strain and the stt7 mutant of Chlamydomonas under state 1 and state 2 conditions, was investigated.[Stt7] (Mus musculus) PubMed
6431.
Potential chicken specific miR-143 target sites were also validated for LPIN1, PCK2, PYCR2, METTL14, SLC2A2 and TNFSF10. (Mus musculus) PubMed
6432.
STAR-2 binds tightest to a consensus hexamer that more closely resembles the sequence preferred by Qk-1 rather than GLD-1 (STAR-2). (Mus musculus) PubMed
6433.
Results indicate that PsiA is also involved in prestalk cell differentiation in Dictyostelium discoideum strain Ax2: [PsiA] (Mus musculus) PubMed
6434.
MEAT1 shows no appreciable conformational change upon UTP binding and apparently does not require RNA substrate to select a cognate nucleoside triphosphate.[MEAT1] (Mus musculus) PubMed
6435.
Data show that structural study combined with functional analyses provides essential information for understanding the reaction mechanism of bacterial UGPases, as well as a platform for the development of novel antibacterial agents: [HpUGPase] (Mus musculus) PubMed
6436.
Noncollagenous region of the streptococcal collagen-like protein is a trimerization domain that supports refolding of adjacent homologous and heterologous collagenous domains. (Mus musculus) PubMed
6437.
Dil 1 protein is required to prevent meiosis I homolog non-disjunction. (Mus musculus) PubMed
6438.
Large and irregular oil clusters were observed in cells of double mutant seeds. [OLE16 and OLE18] (Mus musculus) PubMed
6439.
demonstrate that the expression of a Medicago truncatula gene named Vapyrin is essential for arbuscule formation, and also for efficient epidermal penetration by Arbuscular mycorrhizal fungi. [Vapyrin] (Mus musculus) PubMed
6440.
crystals of nucleoside diphosphate kinase 1 belonged to the trigonal space group P3, with unit-cell parameters a = b = 127.84, c = 275.49 A.[nucleoside diphosphate kinase 1] (Mus musculus) PubMed
6441.
P1 proteins play a key role in maintaining a subtle equilibrium between defense and counter-defense mechanisms, to insure efficient virus multiplication and the preservation of host integrity.[ P1 protein ] (Mus musculus) PubMed
6442.
Pkd1a/b and pkd2 interact to regulate extracellular matrix secretion or assembly, and that altered matrix integrity may be a primary defect underlying autosomal dominant polycystic kidney disease tissue pathologies.[pdk1] (Mus musculus) PubMed
6443.
In this study, they characterize the choC gene encoding a putative highly conserved phospholipid methyltransferase. (Mus musculus) PubMed
6444.
results revealed that seven of the animals (70%) were homozygous for the same combination of microsatellite alleles of myostatin observed in the Texel[Myostatin ] (Mus musculus) PubMed
6445.
The crown of the HIV-1 envelope glycoprotein gp120 V3 has four conserved structural elements.[gp120] (Mus musculus) PubMed
6446.
These data suggest that TaCAD1 is the predominant CAD in wheat stem for lignin biosynthesis and is critical for lodging resistance.[CAD1] (Mus musculus) PubMed
6447.
By inhibiting E-cadherin expression and enhancing ICAM-1 expression, LMP1 may reduce the cell-cell adhesive ability and improve the cell-matrix adhesive ability and migratory ability of nasopharyngeal carcinoma cells. [LMP-1] (Mus musculus) PubMed
6448.
The results demonstrate that MPR1/azetidine-2-carboxylic acid is a safe and efficient selection system that does not involve microbial antibiotic or herbicide resistance genes.[MPR1] (Mus musculus) PubMed
6449.
Expression and characterization of PKL01, an Ndr kinase homolog in Lotus japonicus. (Mus musculus) PubMed
6450.
Subcellular localization, expression patterns and patterns sugar transport ability of OsTMT1 and OsTMT2 were analysed.[OsTMT1, OsTMT2] (Mus musculus) PubMed
6451.
LMP1 is expressed in lymph node metastatases in nasopharyngeal carcinoma. Expression is positively correlated with Fascin, pStat3 and the proliferation index of tumor cells. [LMP-1] (Mus musculus) PubMed
6452.
report on the binding of HIV-1 gp120 to the cytoplasmic C-terminus of the voltage-gated potassium channel BEC1, an interaction that can result in the repression of BEC's activity and the inhibition of HIV-1 particle-release (gp120) (Mus musculus) PubMed
6453.
Dauer pheromone and gpa-3 signaling modulate the coordination of intraflagellar transport of kinesin-II and OSM-3. [kinesin-II] (Mus musculus) PubMed
6454.
ZFP179 plays a crucial role in the plant response to salt stress, and is useful in developing transgenic crops with enhanced tolerance to salt stress.[ZFP179] (Mus musculus) PubMed
6455.
BmTh gene is responsible for the sch mutation, which plays an important role in melanin synthesis producing neonatal larval color.[Sch] (Mus musculus) PubMed
6456.
Active transport of mannitol only takes place when EII(mtl) becomes phosphorylated at Cys(384) in the cytoplasmic B domain. (Mus musculus) PubMed
6457.
Overexpression of ERG11, CDR1 and CDR2 genes is associated with the increase of fluconazole resistance in clinical isolates of C. glabrata. [CDR1; CDR2] (Mus musculus) PubMed
6458.
The four phtosynthetic FNR protein isoforms are each present in the chloroplast in phosphorylated and non-phosphorylated states.[FNR] (Mus musculus) PubMed
6459.
The cloning and characterization of two solanesyl diphosphate synthase genes, OsSPS1 and OsSPS2, in Oryza sativa is reported here. [OsSPS1 and OsSPS2] (Mus musculus) PubMed
6460.
The data support a model in which AnhE acts as a dimeric metallochaperone to deliver cobalt to ANHase. [AnhE] (Mus musculus) PubMed
6461.
The present study investigates the cascade components at the higher integrated level of Sorghum bicolor leaf discs and leaves. PEPC-k up-regulation required light and photosynthetic electron transport.[PEPC-k. PLD] (Mus musculus) PubMed
6462.
Mutation of sarA resulted in a reduced capacity to form a biofilm in all clinical isolates irrespective of the functional status of agr.[sarA, agr] (Mus musculus) PubMed
6463.
The structure of scpB-lmb intergenic region in 111 GBS isolates belonging to the intraspecies major clonal complexes (CCs).[scpB, lmb] (Mus musculus) PubMed
6464.
Xac catalase-specific activity is induced during the stationary phase of growth in parallel with the bacterial resistance to peroxide challenge.[KatE] (Mus musculus) PubMed
6465.
Enterocin X, composed of peptides (Xalpha and Xbeta), is a novel class IIb bacteriocin of strain KU-B5, which displays variably enhanced or reduced antibacterial activity compared to each peptide individually. [enterocin X] (Mus musculus) PubMed
6466.
Both cyclin C and Cdk8 are regulated during development in response to extracellular signals and the levels of these proteins are important in controlling the timing of developmental processes.[Cyclin C] (Mus musculus) PubMed
Our results suggest that cAMP-CRP-mediated downregulation of phage adsorption may contribute to a mechanism for the V. cholerae O1 strains to survive predation by multiple environmental phages. [CRP] (Mus musculus) PubMed
6469.
physicochemical properties and crystal structure of cytochrome c(554)[cytochrome c554] (Mus musculus) PubMed
6470.
The phylogeny of GimA was unravelled and investigate its island character was investigated.[GimA] (Mus musculus) PubMed
6471.
both RpoS and OxyR are required to promote expression of both the katG-dpsA operon and dpsA gene. [RpoS, OxyR, katG, dpsA] (Mus musculus) PubMed
6472.
examine the transcriptional regulator Wor1, a master regulator of white-opaque switching in the human fungal pathogen Candida albicans; involves an unusual coupling between two dissimilar, covalently linked domains (Mus musculus) PubMed
6473.
We cloned a bacterial copper-containing nitrite reductase (NirK) homolog gene of Aspergillus oryzae (AonirK). [AonirK] (Mus musculus) PubMed
6474.
In this study, we cloned and sequenced cDNA and genomic DNA carrying ocpO encoding carboxypeptidase O. [carboxypeptidase O] (Mus musculus) PubMed
GAP-43 protein expression in airway afferent neurons can be induced by allergic airway inflammation. (Mus musculus) PubMed
6477.
The overall morphology of the strain carrying the un-7 mutation is compared to strains carrying the png-1 mutation and these mutations are evaluated in the context of other temperature-sensitive mutants in Neurospora.[png-1, un-7] (Mus musculus) PubMed
6478.
Genetic partners of Rps15p were identified in Saccharomyces cerevisiae and elucidate the role of Rps15 during ribosomal biogenesis, was elucidated.[Rps15p] (Mus musculus) PubMed
6479.
The presented data, which was obtained in the test-tube experiments, adds GCN4 and c-Jun to the pool of proteins with multiple functions.[GCN4] (Mus musculus) PubMed
6480.
Neurokinin B acts via the neurokinin-3 receptor in the retrochiasmatic area to stimulate luteinizing hormone secretion. [Neurokinin 3 receptor, sheep] (Mus musculus) PubMed
6481.
The structural plasticity of gp120 can accommodate multiple modes of antibody binding within the CD4 binding site.[gp120] (Mus musculus) PubMed
6482.
Show that repeated duplication events have led to at least five carnitine palmitoyltransferase I (CPT I) isoforms in rainbow trout. (Mus musculus) PubMed
6483.
presents the structure of the par toxin Fst, the first atomic resolution structure of a component of an antisense regulated toxin-antitoxin system; and mode of membrane binding was determined by epr and molecular dynamics simulation [Fst] (Mus musculus) PubMed
6484.
The crystal structure at 2.3 A resolution of the carboxyltransferase domain of yeast ACC in complex with tepraloxydim, is reported.[ACC] (Mus musculus) PubMed
6485.
Mutations at positions 186 and 194 in the HA gene of the H1N1 influenza virus improve virus replication. [HA] (Mus musculus) PubMed
6486.
1.9 A crystal structure of the HDV ribozyme shows the HDV ribozyme may use a combination of metal ion Lewis acid and nucleobase general acid strategies to effect RNA cleavage. (Mus musculus) PubMed
6487.
The data indicate that Verotoxin 2 (VT2) plays a role in the adherence of EHEC O157:H7 to intestinal epithelial cells, possibly by increasing the expression of the host receptor beta1-integrin. [VT2] (Mus musculus) PubMed
6488.
The SO3177 gene, encoding a putative formyltransferase and situated in a cell surface polysaccharide biosynthesis gene cluster, was responsible for the increased currentn and affects cell adhesion to graphite anodes. (Mus musculus) PubMed
6489.
mRNPs containing TcDHH1 are involved in mRNA metabolism, regulating the expression of at least epimastigote-specific genes[TcDHH1] (Mus musculus) PubMed
6490.
Med8, Med18, and Med20 can fold in different ways to form both soluble monomeric proteins and different distinct subcomplexes.[Med8, Med18, Med20] (Mus musculus) PubMed
6491.
discovered two patches of residues-one on H3 and a second on H4-that are crucial for sporulation but not critical for mitotic growth, and likely comprise interactive nucleosomal surfaces[histone H3 and Histone h4; strain is SK1] (Mus musculus) PubMed
6492.
In addition to their role in initiation, Ligatin and MCT-1/DENR can promote release of deacylated tRNA and mRNA from recycled 40S subunits after ABCE1-mediated dissociation of post-termination ribosomes[MCT-1,DENR] (Mus musculus) PubMed
6493.
The 165-kD crystal structure of the central domain of Sec16 in complex with Sec13 was solved at 2.7-A resolution [sec13 & sec16] (Mus musculus) PubMed
6494.
During the acts of DNA double-strand-break repair, there is competition of DNA polymerases I, II and III with DNA Pol IV for action at the primer terminus.[DNA polymerases I, II, III, IV] (Mus musculus) PubMed
6495.
These data indicate that RNAPII polyubiquitylation requires cooperation between distinct, sequentially acting ubiquitin ligases.[RNAPII] (Mus musculus) PubMed
6496.
These results define the polypeptide path during SecA-mediated protein translocation.[SecA] (Mus musculus) PubMed
6497.
The active form of Puf5 is localised to cytoplasmic foci.[Puf5] (Mus musculus) PubMed
6498.
The data indicates that cCAT-2A is a low affinity, high velocity transporter for lysine and arginine and is the cCAT-2 isoform responsible for lysine and arginine transport in avian skeletal muscle (cationic amino acid transporter-2). (Mus musculus) PubMed
6499.
The Escherichia coli O103 3-hydroxybutanoyltransferase gene involved in the synthesis of a Fuc3N derivative [fdhC] (Mus musculus) PubMed
6500.
These findings suggest that the increased bacteriophage-encoded enterotoxin A (sea) expression in S. aureus caused by acetic acid induced the sea-encoding prophage, linking SEA production to the lifecycle of the phage.[sea] (Mus musculus) PubMed
6501.
Confining Fus3 in the nucleus, via fusion to a histone H2B, reduced MAPK activation and diminished all responses (pheromone-induced gene expression, cell cycle arrest, projection formation, and mating). [Fus3] (Mus musculus) PubMed
6502.
The geometry of the axial ligands of the hemes in the triheme cytochrome PpcA from Geobacter sulfurreducens was determined in solution for the ferric form.[PpcA] (Mus musculus) PubMed
6503.
Transcription of chpA was dependent on chpR, a CadC family transcriptional regulator located upstream of, and divergently transcribed from, chpAB.[chpR] (Mus musculus) PubMed
6504.
IDEF1 and IDEF2 are constitutively expressed during both vegetative and reproductive stages. The spatial expression patterns of IDEF1 and IDEF2 overlap with their target genes in restricted cell types, but not in all cells. [IDEF1] (Mus musculus) PubMed
6505.
OsCIPK14 and OsCIPK15 interact with Ca2+ sensor proteins and are involved in microbial defense responses, including hypersensitive cell death, mitochondrial dysfunction, phytoalexin biosynthesis, and pathogenesis-related gene expression. [CIPK14; CIPK15] (Mus musculus) PubMed
6506.
The AnBud3-Rho4 module acts downstream of the septation initiation network to mediate recruitment of the formin SepA to the site of contractile actin ring assembly.[Bud3, Rho4] (Mus musculus) PubMed
6507.
A new FeEnt receptor CfrB was indentified and characterized using both in vitro and in vivo systems. [CfrB] (Mus musculus) PubMed
6508.
OsPHR2 physically regulates the expression of OsPT2. OsSPX1 suppresses the function of OsPHR2 in regulation of OsPT2 expression in roots. [SPX1; PT2] (Mus musculus) PubMed
6509.
Genetic analyses with other maize mutants with variegated leaves and impaired carbohydrate partitioning suggest that Psc defines an independent pathway.[Psc] (Mus musculus) PubMed
6510.
The Eps1 orthologous regions from rice, Aegilops tauschii, and Brachypodium distachyon were compared as part of current efforts to clone this gene.[Eps-1] (Mus musculus) PubMed
6511.
Our 3-D structure results of the Dihydropyridine receptor propose a model in which the beta subunit may regulate ion channel function by acting as a hinge between alpha(1) and alpha(2)delta subunits of the DHPR. [DHPR] (Mus musculus) PubMed
6512.
Ssl3076 protein (GgpR) represses ggpS expression under low-salt conditions, whereas in salt-shocked and salt-acclimated cells a stress-proportional ggpS expression occurs, leading to glucosylglycerol accumulation. [GgpR] (Mus musculus) PubMed
6513.
SspB, particularly in the presence of staphylococcal protein A, may reduce the number of functional phagocytes at infection sites, thus facilitating colonization and dissemination of S. aureus.(SspB) (Mus musculus) PubMed
6514.
Stn1 interacts with Ten1 through an alpha-helix, in a manner analogous to the interaction between the comparable subunits of the replication protein A complex.[Stn1, Ten1] (Mus musculus) PubMed
6515.
In hxk2 deletion mutant CEN.PK, growth rate collapses and derepression occurs on the physiological level, while the hxk2 deletion mutant S288C descendant FY4 still grows like the parent strain and shows a fully repressed metabolism.[HXK2] (Mus musculus) PubMed
6516.
The proximal consequence of LTV1 mutations is inhibition of the cytoplasmic maturation of 40S subunits and nuclear retention of pre-40S subunits is a downstream consequence of the failure to release and recycle critical factors back to the nucleus.[Ltv1] (Mus musculus) PubMed
6517.
Swm2p is required for a substrate-specific activity of Tgs1p.[Tgs1, Swm2] (Mus musculus) PubMed
6518.
Cleavage of HA by plasmin control the virulence of H1N1 influenza virus.[HA] (Mus musculus) PubMed
6519.
PB2 associates with CCT2 as a monomer and the CCT binding site is located in a central region of the PB2 protein. . [PB2] (Mus musculus) PubMed
6520.
Tyrosine residue at position 76 of M2 was critical for the formation of infectious virus particles. [M2] (Mus musculus) PubMed
6521.
M2 protein cholesterol recognition/interaction amino acid consensus (CRAC) motif is a virulence determinant which may facilitate virus replication in vivo but is not required for basic virus replication in tissue culture. [M2 protein] (Mus musculus) PubMed
6522.
Fitness epistasis among amino acids of a functionally important region of the human immunodeficiency virus type 1 (HIV-1) exterior envelope glycoprotein (gp120), was investigated.[gp120] (Mus musculus) PubMed
6523.
A major function of RecG is to curb potentially pathological replication initiated via PriA protein at sites remote from oriC.[RecG, RuvA, RuvB, RuvC] (Mus musculus) PubMed
6524.
AgsA regions for lysozyme chaperone activity are located outer surface of the oligomeric complex while those regions important for insulin are located inside the oligomeric complex and those for MDH are located within the N-terminal arm. (AgsA) (Mus musculus) PubMed
6525.
CbaX displays typical features of a generic Surf1 factor essential for binding and positioning the heme a moiety for correct assembly into the protein scaffold of oxidase subunit I. [CbaX] (Mus musculus) PubMed
6526.
These results suggest that ttcsp2 mRNA acts as a 'thermosensor' that responds to temperature downshift by changes in its own secondary structure. (ttcsp2) (Mus musculus) PubMed
6527.
This work suggests that, although NRG1 repression plays a key role in regulating true hyphal growth, it apparently does not regulate pseudohyphal growth in the same fashion.[NRG1] (Mus musculus) PubMed
6528.
The human cytomegalovirus microRNA miR-UL112 was found to act synergistically with cellular microRNA to escape immune elimination. (Mus musculus) PubMed
6529.
A single mutation in hfq was responsible for the multiple benefits under glucose limitation through changes in at least five regulation targets. [Hfq] (Mus musculus) PubMed
6530.
Triticum aestivum-5B2 (( Ta ) 5B2) is suggested to be a wheat analogue of human CDK2 enzyme.[5B2] (Mus musculus) PubMed
6531.
These data indicate that TaNF-YC11 is potentially involved in regulation of photosynthesis-related genes.[TaNF-YC11] (Mus musculus) PubMed
6532.
analysis of differences in large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4 [KCC4/SLC12A7] (Mus musculus) PubMed
6533.
the pK(a) values of each of the imidazole rings of the two ligating histidines (His134 and His154) in the oxidized and reduced states of the Rieske protein [Rieske protein] (Mus musculus) PubMed
6534.
Maternal deprivation affects the intraneuronal locations involved in the maturation of GnRH from proGnRH in the preoptic area-hypothalamus of weanlings.[GAP] (Mus musculus) PubMed
6535.
This study concluded that VjbR and N-dodecanoyl homoserine lactone signaling molecule (C12-HSL) contribute to virulence and survival by regulating expression of virulence mechanisms.[C12-HSL] (Mus musculus) PubMed
6536.
Ciona heart ANP might play a similar role like in the heart of vertebrates.[ANP] (Mus musculus) PubMed
6537.
YCF45 protein is targeted into the mitochondrion but not plastids. [YCF45] (Mus musculus) PubMed
6538.
Interaction of UL112-113 with UL44 is necessary for efficient viral DNA replication. [UL113] (Mus musculus) PubMed
6539.
An htrA mutant had 20-23% less growth than an htrA-complemented strain of S. mutans K7 under acidic conditions.When the htrA expression level was restored, the normal growth phenotype was restored under acid stress. HTRA. (Mus musculus) PubMed
6540.
These results indicate that the vital role of both Sal1p and Aac2p is to maintain the essential intramitochondrial ATP pool owing to their ability to transport adenine nucleotides.[Sal1 & Aac2] (Mus musculus) PubMed
6541.
The putative N-peptide binding area in Sec1p domain 1 is important for Mso1p binding, and Mso1p can interact with Sso1p and Sso2p.[Sec1p, Mso1p] (Mus musculus) PubMed
6542.
SSD1 controls plant elongation by controlling cell division in higher plants.[SSD1] (Mus musculus) PubMed
6543.
One gene candidate, TcAAAP411, was characterized as a very specific, high-affinity, l-arginine permease.[AAAP411] (Mus musculus) PubMed
6544.
examination of the DNA binding thermodynamics of Klenow and Klentaq to different DNA structures [DNA polymerase I] (Mus musculus) PubMed
6545.
novel insights into the molecular structure of OmcA in solution and its interaction with insoluble hematite and small organic ligands [OmcA] (Mus musculus) PubMed
6546.
The BTas transactivator contains two major functional domains: the N-terminal DNA-binding domain (residues 1-133) and the C-terminal activation domain (residues 198-249). [Ttas] (Mus musculus) PubMed
6547.
trimeric state and monomeric state of EhCaBP1 [EhCaBP1] (Mus musculus) PubMed
6548.
We showed MDV pUL49.5 down-regulates MHC class I directly and identified its cytoplasmic tail as essential for this function. [UL49.5] (Mus musculus) PubMed
6549.
IgT, an immunoglobulin isotype of unknown function, acts like a mucosal antibody [IgT] (Mus musculus) PubMed
6550.
the effect of membrane thickness on prestin [prestin] (Mus musculus) PubMed
6551.
The newly described Lip2 has 43 kDa molecular weight, C8 substrate specificity and optimal reaction temperature of 50 degrees C.[Lip2] (Mus musculus) PubMed
6552.
Purification and characterization of mycoferritin [mycoferritin] (Mus musculus) PubMed
6553.
Purified SnrA and cnr were investigated for their capacity to activate several mutagens in the Ames test as well as their kinetic parameters K(m) and V(max).[SnrA, cnr] (Mus musculus) PubMed
6554.
OsGA2ox6 mainly affects plant stature, and the dominant dwarf trait of the H032 mutant can be used as an efficient dwarf resource in rice breeding.[OsGA2ox6] (Mus musculus) PubMed
6555.
PDA1 is required for post-meiotic tapetal development and pollen/microspore formation in rice.[PDA1] (Mus musculus) PubMed
6556.
SMS1 gene will be a novel gene that regulates the two developmental processes.[SMS1] (Mus musculus) PubMed
6557.
MIP1 interacted with MOC1 both in vitro and in vivo {MIP1 & MOC1] (Mus musculus) PubMed
6558.
This study identifies CRL4Cdt2 as the ubiquitin ligase for Xic1 in the egg.[CRL4Cdt2] (Mus musculus) PubMed
6559.
A model of HisK:GalR is proposed to explain how galactose mediates the expression of the gal operon in T. tengcongensis. [HisK, GalR] (Mus musculus) PubMed
6560.
osmads34 mutants developed altered inflorescence morphology, with an increased number of primary branches and a decreased number of secondary branches, and displayed a decreased spikelet number and altered spikelet morphology. (Mus musculus) PubMed
6561.
These data indicate that 53R is an essential viral protein that is required for replication in vitro and suggest it plays a critical role in virion formation. [53R] (Mus musculus) PubMed
6562.
The C-terminal extension is responsible for redox regulation of ZmGLYK. [GLYK] (Mus musculus) PubMed
6563.
Gene expression of Xyl1, but not Xyl2 and Xyl3, is induced by xylose. [Xyl1,Xyl2,Xyl3] (Mus musculus) PubMed
6564.
K5 lyase KflA combines a viral tail spike structure with a bacterial polysaccharide lyase mechanism [KflA] (Mus musculus) PubMed
6565.
In conclusion, these data reinforce the notion that Helicobacter pylori neutrophil-activating protein has a pivotal role in sustaining a prolonged activation of monocytes and neutrophils. (Mus musculus) PubMed
6566.
The authors conclude that ATG9 and hence macroautophagy has a protective role during pathogen infection.[ATG9] (Mus musculus) PubMed
6567.
The activities of Bim1 and Bik1, two +TIP proteins from budding yeast and members of the EB1 and CLIP-170 families, respectively, are described.[Bim1, Bik1] (Mus musculus) PubMed
6568.
Mdm38 and Mba1 exhibit overlapping regulatory functions in translation of selected mitochondrial mRNAs.[Mdm38 and Mba1] (Mus musculus) PubMed
6569.
The reversible association of RCA with the thylakoid membrane is ATP and pH. [RCA] (Mus musculus) PubMed
6570.
Calflagin inhibition prolongs host survival and suppresses parasitemia in Trypanosoma brucei infection (Mus musculus) PubMed
6571.
TbPRMT6 is a type I protein arginine methyltransferase that contributes to cytokinesis in Trypanosoma brucei (Mus musculus) PubMed
6572.
extension of NS1 to 230 aa had no impact on replication; minimal effects on replication, pathogenicity and transmission observed in animal model; data suggest 2009 H1N1 virus optimized to replicate efficiently without requiring certain NS1 functions[NS1] (Mus musculus) PubMed
6573.
Under ex vivo conditions, CaGto1 and CaGtt11 become transitorily upregulated inside macrophages and neutrophils.[Gto1 & Gtt11] (Mus musculus) PubMed
6574.
A Plasmodium falciparum transcriptional cyclin-dependent kinase-related kinase with a crucial role in parasite proliferation associates with histone deacetylase activity (Mus musculus) PubMed
6575.
OSIAGP codes for an arabinogalactan protein homologue, and its promoter contains several pollen-specificity and light-regulatory elements active during pollen development and pollen tube growth. [OSIAGP] (Mus musculus) PubMed
6576.
crystal structure provides a possible unification of the discrete site versus continuum conduction models (M2 proton channel) (Mus musculus) PubMed
6577.
Analysis of lacZ expression in several deletion mutants confirmed that the effect of Snf7p on anaerobic upregulation of TIR1 involved Rim101p.[Snf7, TIR1 & Rim101] (Mus musculus) PubMed
6578.
OXP1/YKL215c, an uncharacterized open reading frame of Saccharomyces cerevisiae, encodes a functional ATP-dependent 5-oxoprolinase of 1286 amino acids.[OXP1] (Mus musculus) PubMed
6579.
data suggest a role for RfxA in linking cellular division with morphogenesis, particularly during conidiation and yeast growth [RfxA] (Mus musculus) PubMed
6580.
study reports that CaNdt80p is indeed required for hyphal growth in response to different filament-inducing cues and for the proper expression of genes characterizing the filamentous transcriptional program [Ndp80] (Mus musculus) PubMed
6581.
These data show that Rck2p regulates cellular responses to cell wall stresses, filamentation and virulence in the human fungal pathogen Candida albicans.[Rck2] (Mus musculus) PubMed
6582.
Suppression of the C. elegans thioredoxin orthologs trx-1 and trx-2, involved in the redox chaperone activity of exo-3, overrides the protective effect of cep-1 RNAi treatment on neuronal integrity, neuronal function, mean and maximum life span.[TRX-2] (Mus musculus) PubMed
6583.
Lysine 161 is not absolutely essential for catalysis.[DHDPS] (Mus musculus) PubMed
6584.
MtsR is a global regulator in GAS that shapes the expression of vital virulence factors and genes involved in metabolic functions and metal transport, and we discuss the implications for the GAS disease process.(MtsR) (Mus musculus) PubMed
6585.
These results demonstrate that TSRF1 enhances the osmotic and drought tolerance of rice by modulating the increase in stress responsive gene expression.[TSRF1] (Mus musculus) PubMed
6586.
Inhibition of gliding motility without inhibition of micronemal secretion by 1NM-PP1 suggests a function for Toxoplasma gondii CDPK1 in gliding motility. (Mus musculus) PubMed
6587.
Subdomain 3 of Plasmodium falciparum VAR2CSA DBL3x is a minimal chondroitin sulfate A-binding region [VAR2CSA] (Mus musculus) PubMed
6588.
IE62 has two critical but discrete roles following varicella zoster virus entry: to induce expression of viral genes and to disarm the interferon-dependent antiviral defense through a novel mechanism that prevents IRF3 phosphorylation.[IE62] (Mus musculus) PubMed
6589.
Rrp46 forms a homodimer separately from exosome complexes and, dimeric oRrp46 had both phosphorolytic RNase and hydrolytic DNase activities and is a component of the machinery that cleaves DNA during apoptosis[Rpr46] (Mus musculus) PubMed
6590.
Data show that T. brucei possesses a member of the Trk/HKT superfamily of monovalent cation permeases, HKT1, which so far had only been known from bacteria, archaea, fungi, and plants [HKT1]. (Mus musculus) PubMed
6591.
Artemisinin resistance in western Cambodia is not linked to pfATPase6, as was suggested by earlier studies. [pfATPase6] (Mus musculus) PubMed
6592.
SERA1 and SERA2 loss-of-function lines progressed normally through the parasite life cycle, suggesting a specialized, non-vital role for serine-type SERAs in vivo.[SERA1 and SERA2] (Mus musculus) PubMed
6593.
Isogenic hla-negative (Deltahla) strains caused skin lesions in a mouse infection model that were significantly smaller than those caused by wild-type USA300 [hla] (Mus musculus) PubMed
Study identified a mosGCTL-1 homolog, CPIJ010995, and found that silencing it reduced the WNV burden compared to the control group suggesting that Culex mosGCTL-1 plays a role in facilitating WNV infection in Culex mosquitoes.[CPIJ010995, Culex mosGCTL-1] (Mus musculus) PubMed
6596.
Data show that the transcriptional activity of Neurog3 affects migration and differentiation of ectopic endocrine cells in chicken endoderm. [Neurog3] (Mus musculus) PubMed
6597.
Localization and targeting of an unusual pyridine nucleotide transhydrogenase in Entamoeba histolytica (Mus musculus) PubMed
6598.
Data demonstrate that DBF-2 is involved in three fundamental processes in a filamentous fungus: cell cycle regulation, glycogen biosynthesis, and conidiation, and functions as a link between Hippo and glycogen metabolism pathways. (Mus musculus) PubMed
6599.
The authors propose that PIF1, PIF2, PIF3, and P74 form an evolutionarily conserved complex on the occlusion-derived virus surface, which has an essential function in the initial stages of baculovirus oral infection.[PIF1, PIF2 & PIF3] (Mus musculus) PubMed
6600.
Mutations in the middle of the M53 open reading frame (ORF) resulted in dominant negative mutants inhibiting virus replication by approximately 100-fold, mutations at the C terminus resulted in up to 1,000,000-fold inhibition of virus production.[M53] (Mus musculus) PubMed
6601.
Cif deamidated NEDD8, which abolished activity of neddylated Cullin-RING ubiquitin ligases (CRLs); ubiquitination and ubiquitin-dependent degradation of CRL substrates were impaired by Cif in EPEC-infected cells [Cif] (Mus musculus) PubMed
6602.
PB1-F2 protein has various lengths, amino acid sequences, cellular localizations, and functions in different strains, which result in strain-specific pathogenicity. (Mus musculus) PubMed
6603.
findings show CHBP was a potent inhibitor of the eukaryotic ubiquitination pathway; CHBP acted as a deamidase that specifically and efficiently deamidated Gln40 in ubiquitin and ubiquitin-like protein NEDD8 in vitro and during Burkholderia infection[CHBP] (Mus musculus) PubMed
6604.
These results suggest a division of labor between Isw1 and Isw2, whereby Isw2 maintains repressive chromatin structure at gene ends while Isw1 has a similar function at mid-coding regions.[Isw1] (Mus musculus) PubMed
6605.
results suggest that human-derived mutations in HA of H5N1 viruses can affect viral replication efficiency and organ tropism [HA] (Mus musculus) PubMed
6606.
L35 assembles in the nucleolus and binds to early pre-60S ribosomal particles (L35). (Mus musculus) PubMed
6607.
Data show that Rac1 and betaPIX are indirect targets of NS5 acting through the multifunctional polarity protein Scribble to oppose neuronal differentiation [NS5]. (Mus musculus) PubMed
6608.
Redox titration analysis revealed that the midpoint reduction potential of OmcZ(S) is approximately -220 mV (versus the standard hydrogen electrode [SHE]) with nonequivalent heme groups that cover a large reduction potential range (-420 to -60 mV).[OmcZ] (Mus musculus) PubMed
6609.
The authors show that the P1 domain is sufficient to determine which response regulators will be phosphorylated in vitro while the P5 domain is sufficient to localize the CheAs to a specific chemosensory cluster.[CheA2, CheA3 & CheA4] (Mus musculus) PubMed
6610.
MoTea4 plays an important role in organizing the F-actin cytoskeleton and is essentially required for polarized growth and morphogenesis during asexual and pathogenic development in Magnaporthe.[MoTea4] (Mus musculus) PubMed
6611.
report an all-atom model of the macromolecular structure of Panton-Valentine leukocidin in its octameric, pre-pore conformation that confirms and extends our understanding of the toxin's mechanism of action [LukF, LukS] (Mus musculus) PubMed
6612.
This study investigates the time-resolved reaction between fully reduced ba3 Cytochrome c oxidase and O2 in variants where Thr-312 and Thr-315 were modified.[ba3 Cytochrome c oxidase] (Mus musculus) PubMed
6613.
These findings indicate that close interaction between adhesive and anchoring pilin domains of CfaE keeps the former in a low-affinity state that toggles into a high-affinity state upon separation of two domains.[CfaE] (Mus musculus) PubMed
6614.
Physical interaction between CP and HC-Pro is important for potyviral aphid transmission.[Coat protein] (Mus musculus) PubMed
6615.
Transcription of the nagF and nagE2 genes is induced by N-acetylglucosamine.[nage2] (Mus musculus) PubMed
6616.
Disruption of the CIN1 gene had a pleiotropic effect on growth, cytokinesis, intracellular transports and the production of virulence factors. [Cin1] (Mus musculus) PubMed
6617.
show that the intra-antenna energy transfer processes in CP43 and CP47 are surprisingly fast[CP47] (Mus musculus) PubMed
6618.
FgPTC1 plays an important role in regulating the hyphal growth and virulence of F. graminearum.[FgPTC1] (Mus musculus) PubMed
6619.
P-body formation is disrupted in strains with deleted Edc3(enhancer of decapping) or CutA (encodes a nucleotidyltransferase); the signalled degradation of specific transcripts are dependent on nuclease activity of Caf1 but not Ccr4[Edc3,CutA, Caf1,Ccr4] (Mus musculus) PubMed
6620.
Data indicate that the activity of SpGH38 alpha-mannosidase, together with its genomic context strongly hints at a function in the degradation of host N- or possibly O-glycans: [GH38 alpha-mannosidase] (Mus musculus) PubMed
6621.
These results suggested that the double silencing of cytosolic OsApx genes induced compensatory antioxidant mechanisms in rice while single knockdown of these genes did not, which resulted in the impairing of normal plant development. [Apx1 and Apx2] (Mus musculus) PubMed
6622.
the pollen disrupted for OsSUT1 is dysfunctional, however, starch accumulation during pollen development was not affected by disruption of OsSUT1 [SUT1] (Mus musculus) PubMed
6623.
Deleting ARP2 abolished hyphal formation, generated round and swollen yeast phase cells, disrupted cortical actin patches and blocked virulence in mice.[ARP2] (Mus musculus) PubMed
6624.
Study identified genes that are expressed in a monopolar cell (Amfutsch and Amtau) or ventral medulla-preferential manner (AmMESK2) in insect OLs: [Amfutsch, Amtau and AmMESK2] (Mus musculus) PubMed
6625.
The crystal structure of the urease maturation protein UreE from Helicobacter pylori has been determined in its apo form at 2.1 A resolution, bound to Cu(2+) at 2.7 A resolution, and bound to Ni(2+) at 3.1 A resolution. [UreE] (Mus musculus) PubMed
6626.
Reresults indicate that QDE-1 displays five distinct catalytic activities, which can be dissected by mutating critical amino acids or by altering reaction conditions. [QDE-1] (Mus musculus) PubMed
6627.
Glyoxalase I (GloI) and one of the two glyoxalases II (cGloII) were located in the cytosol of the blood stages. The second glyoxalase II (tGloII) was detected in the apicoplast pointing to alternative metabolic pathways.[GloI & GloII] (Mus musculus) PubMed
6628.
root-yield-1.06 has a major constitutive effect on root traits, plant vigour and productivity across water regimes, genetic backgrounds, and inbreeding levels [root-yield-1.06] (Mus musculus) PubMed
6629.
Overexpression of the TcPOT1.1 and TcPOT1.2 genes in T. cruzi epimastigotes revealed that TcPOT1.1 and TcPOT1.2 were high-affinity transporters that recognized both putrescine and cadaverine but not spermidine or spermine.[POT1.1 & POT1.2] (Mus musculus) PubMed
6630.
Data show that the PfSERCA (PfATP6) functional domains were very well conserved, with non synonymous mutations located outside the functional domains: [PfATP6] (Mus musculus) PubMed
6631.
The authors show that FlbB activates the expression of FlbD, both factors then jointly activate brlA, a C(2)H(2) zinc finger transcription factor, which plays a central role in spore formation.[FlbB, FlbD & brlA] (Mus musculus) PubMed
6632.
Data suggest that small, non-coding RNA EBER1 plays an oncogenic role in EBV associated malignant disease: [EBER1] (Mus musculus) PubMed
6633.
The presence of cagE and virB11 cag pathogenicity island genes shows that they are important factors for the pathogenesis and malignancy of gastric cancer related to H. pylori. [cagE, virB11] (Mus musculus) PubMed
6634.
Results report the crystal structure of the MID domain of the eukaryotic Argonaute protein QDE-2 from Neurospora crassa [QDE-2]. (Mus musculus) PubMed
6635.
Inhibition of oxidative phosphorylation perturbs sugar regulation of Amy3D expression in the embryo. [Amy3D] (Mus musculus) PubMed
6636.
kch1 insertion mutants show impaired cell expansion and increased division. KCH overexpression delays nuclear positioning and mitosis. [KCH1] (Mus musculus) PubMed
6637.
Near-optimal catalytic properties are observed for diacylglycerol kinase in micelles composed of lysomyristoylphosphatidylcholine. [diacylglycerol kinase] (Mus musculus) PubMed
6638.
BR2 is expressed in nodal meristems, and analyses of auxin transport and content indicate that BR2 function in these grass-specific tissues is analogous to ABCB1 function in the shoot and root apex of Arabidopsis [BR2] (Mus musculus) PubMed
6639.
CBP70 is a plastid transcription elongation factor or a modulator of plastid elongation factor activity. [CBP70] (Mus musculus) PubMed
6640.
Data suggest that OsNAC5 may be a useful gene that can improve the stress tolerance of without affecting its growth [OsNAC5] (Mus musculus) PubMed
6641.
The authors show that Fer3, a non-ribosomal peptide synthetase, Fer4, an enoyl-coenzyme A (CoA)-hydratase, and Fer5, an acylase, are required for ferrichrome A production.[Fer3, Fer4 & Fer5] (Mus musculus) PubMed
6642.
The effects of deleting the genes encoding ACL on growth and development, were investigated.[ATP citrate Lyase] (Mus musculus) PubMed
6643.
This study has uncovered a multitude of novel regulatory targets of SnStuA and has highlighted the critical role of this gene product in the pathogenicity of Stagonospora nodorum.[StuA] (Mus musculus) PubMed
6644.
GH3-1 expression increased at the onset of ripening (veraison), suggesting that it might be involved in the establishment and maintenance of low indole-3-acetic acid concentrations in ripening berries[GH3-1] (Mus musculus) PubMed
6645.
Localization of BUD4 as a cortical ring prior to septation initiation was independent of functional BUD3 or RGF3.[BUD4, BUD3 & RGF3] (Mus musculus) PubMed
6646.
A knockout mutation in OsCOL4 causes early flowering. OsCOL4 acts as a repressor upstream of Ehd1. [COL4] (Mus musculus) PubMed
6647.
Ca(2+)/calmodulin-dependent protein kinase plays a key role in the coordinated induction of infection thread formation and nodule organogenesis. [CCaMK] (Mus musculus) PubMed
6648.
SNL is a novel gene involved in flower development in rice.[SNL] (Mus musculus) PubMed
6649.
Loss of MtNST1 function resulted in reduced lignin content, associated with reduced expression of most lignin biosynthetic genes, and a smaller reduction in cell wall polysaccharide content. [NST1] (Mus musculus) PubMed
6650.
Data show that XA21 is glycosylated and is primarily localized to the ER and also to the plasma membran: [XA21] (Mus musculus) PubMed
6651.
the biochemical and functional characterization of the protein product (Wzy) of the gene annotated as the putative O-antigen polymerase [Wzy] (Mus musculus) PubMed
6652.
structure features of alpha-galactosidase and substrate recognition and specificity [alpha-galactosidase] (Mus musculus) PubMed
6653.
3 SNPs were identified in field-collected mosquitoes associated with parasite infection in molecular form-dependent patterns: 2 were detected in the Toll5B gene and 1 was detected in the gene encoding insulin-like peptide 3 precursor [ILP3 precursor] (Mus musculus) PubMed
6654.
Deletion of bovine herpesvirus 4 ORF73 did not affect the capacity of the virus to replicate in vitro, but it prevented latent infection in vivo using a rabbit model.[ORF73] (Mus musculus) PubMed
6655.
CYP736B transcript was up-regulated in Xylella fastidiosa infection resistant plants and down-regulated in Xylella fastidiosa infection susceptible plants[CYP736B] (Mus musculus) PubMed
6656.
Extensive mapping showed that all of the information for nuclear import resides within the small p14 protein in a bipartite nuclear localization signal composed of the signature RRKRRR and a region of the RNA recognition motif domain.[p14] (Mus musculus) PubMed
6657.
Hfq negatively regulates the expression of tviA at early stage of hyperosmotic stress.[tviA, Hfq] (Mus musculus) PubMed
NUE is a histone methyltransferase that targets histones H2B, H3 and H4 and itself (automethylation). [NUE] (Mus musculus) PubMed
6660.
Data show that interaction of KtrA and KtrE with KtrB increased the K+ uptake rate and conferred Na+ dependency. [KtrA] (Mus musculus) PubMed
6661.
The N-terminal PR domain of SpyCep was sufficient to mediate endothelial cell invasion, whereas for IL-8-degrading activity, the protease domain and the flanking A domain were required.[SpyCep] (Mus musculus) PubMed
6662.
Analysis of mutations in the SURF1 homolog Shy1 revealed Coa4, a new member of the cytochrome oxidase assembly factor family [Coa4]. (Mus musculus) PubMed
6663.
the Saccharomyces cerevisiae AAA-adenosine triphosphatase Cdc48 and its substrate-recruiting cofactor Shp1/Ubx1 are novel components needed for autophagosome biogenesis.[Cdc48, Shp1, Atg8] (Mus musculus) PubMed
6664.
The bud neck-associated kinase Elm1 participates in Kin4 activation and SPOC signaling by phosphorylating a conserved residue within the activation loop of Kin4.[Elm1] (Mus musculus) PubMed
6665.
The Atg9-positive compartments are important for the de novo formation of the phagophore assembly site and the sequestering vesicle that are the hallmarks of autophagy.[Atg9] (Mus musculus) PubMed
6666.
The only consistent mutation in the genomes of viral clones obtained from dying mice was D225G substitution in HA. [hemagglutinin] (Mus musculus) PubMed
6667.
Data suggest that M2 mediates the final steps of budding for influenza viruses, bypassing the need for host ESCRT proteins. [M2] (Mus musculus) PubMed
6668.
These studies revealed that, in addition to its excellent resistance to thermal perturbations, EspP loop 5 (L5) also has remarkable mechanical stability against pulling forces along the membrane norm.[EspP] (Mus musculus) PubMed
6669.
three crystal structures of Escherichia coli LexA in complex with SOS boxes [LexA] (Mus musculus) PubMed
6670.
A novel Fe regulated bHLH transcription factor (OsIRO3) that plays an important role for Fe homeostasis in rice was identified[OsIRO3] (Mus musculus) PubMed
6671.
The plasma membrane protein Sho1 interacts specifically with the MAP kinase Kpp6. Msb2 encodes a mucin-like protein. sho1 and msb2 are not required for mating and do not affect stress responses. [Sho1; Msb2] (Mus musculus) PubMed
6672.
The low-resolution structure determined by small angle X-ray scattering indicated that AbnA is monomeric in solution and its molecular shape is in full agreement with the model.[AbnA] (Mus musculus) PubMed
6673.
structural models of the open and closed conformations [KtrB] (Mus musculus) PubMed
6674.
Study indicated that XdrA is a major activator of spa expression that appears to act directly on the spa promoter and not through previously characterized regulators. [XdrA] (Mus musculus) PubMed
6675.
determined the crystal structure at 2.23 A resolution of D-Alanine:D-Alanine ligase from Streptococcus mutans [D-Alanine:D-Alanine ligase] (Mus musculus) PubMed
6676.
the predicted ribozyme is not essential for LAT's ability to enhance the HSV-1 reactivation phenotype in mice. [LAT] (Mus musculus) PubMed
6677.
These data support a model in which FeuN interacts directly with FeuQ to attenuate phosphorylation of FeuP, and that without this activity, hyperactive signalling through FeuPQ results in cessation of growth or death.[FeuN] (Mus musculus) PubMed
6678.
The cloning and analysis of the jhe gene in the red flour beetle, Tribolium castaneum, a model insect of Coleoptera, is reported.[JHE] (Mus musculus) PubMed
the complex of Tah18 and the CIA protein Dre2 is part of an electron transfer chain functioning in an early step of cytosolic Fe-S protein biogenesis [Tah18 & Dre2] (Mus musculus) PubMed
6681.
Study reports the crystal structure of Maf1 and cryo-electron microscopic structures of Pol III, an active Pol III-DNA-RNA complex, and a repressive Pol III-Maf1 complex.[RNA Pol III] (Mus musculus) PubMed
6682.
Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major (Mus musculus) PubMed
6683.
replication of hepatitis C virus was inhibited by overexpression of ISG15 and NS5A was identified as the substrate for ISGylation (Mus musculus) PubMed
6684.
The present report provides corroborating coding and additional 5' and 3' flanking sequence for three Pinb variants: Pinb-2v1, Pinb-2v2, and Pinb-2v3; additionally, a new Pinb variant, Pinb-2v4, is reported.[Pinb-2v1,Pinb-2v2, Pinb-2v3, Pinb-2v4] (Mus musculus) PubMed
6685.
Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation (Mus musculus) PubMed
6686.
These results suggest multiple role(s) for PfTudor-SN protein mainly in nuclear and splicing processes at asexual blood stages of the malaria parasite.[PfTudor-SN] (Mus musculus) PubMed
6687.
The authors report that CSP-induced and basal comCDE transcription both initiate from the same promoter, P(E).[ComCDE] (Mus musculus) PubMed
6688.
identified the predicted OB-fold as the functional domain of KREPA4 that mediates a high-affinity interaction with the gRNA oligo(U) tail (KREPA4) (Mus musculus) PubMed
6689.
STAT3 is constitutively activated by IGF-1 in scleral fibroblasts. (Mus musculus) PubMed
6690.
The hlyA99 mutant protein is secreted relatively efficiently but haemolytic activity is reduced. [HlyA] (Mus musculus) PubMed
6691.
Heat shock exposure of rice seedlings for 3h in the dark was effective in reducing subsequent Cd-induced decrease in the activity of glutamine synthetase and increase in the specific activity of protease.[Glutamine synthetase] (Mus musculus) PubMed
6692.
These data suggest that Jen1 and Jen2 are expressed in glucose-poor niches within the host, and that these short-chain carboxylic acid transporters may be important in the early stages of infection.[JEN1 & JEN2] (Mus musculus) PubMed
6693.
TUF1 overexpression could restore respiratory growth and fluconazole sensitivity, and could suppress induction of fluconazole resistance by tetracycline treatment. [TUF1] (Mus musculus) PubMed
6694.
A potential role of SmPlk1 in mitosis and/or meiosis in schistosomes was supported by the in situ detection of SmPlk1 transcripts in female vitelline cells and oocytes as well as in male spermatocytes.[Plk1] (Mus musculus) PubMed
6695.
Exposure to low-dose trichloroethylene alters nitric oxide synthase 3 gene expression and function in the developing chick heart. (Mus musculus) PubMed
6696.
Characterization of site-specific mutants of alkylhydroperoxide reductase with dual functionality [ahpC] (Mus musculus) PubMed
6697.
Results indicate that in addition to a role in fumarate respiration, Mfr allows C. jejuni to reduce analogous substrates specifically present in the host gut environment [Mfr]. (Mus musculus) PubMed
6698.
The central cleft of the zebrafish hatching enzyme 1 (ZHE1) represents the active site of the enzyme that is crucial for substrate recognition and catalysis.[ZHE1] (Mus musculus) PubMed
6699.
A conserved immunoreceptor tyrosine-based inhibition motif exists in the cytoplasmic domain between transmembrane domains 7 & 8 in TM9SF5. A conserved TRAF2 binding domain is predicted in the cytoplasmic regions of TM9SF5. TM9SF5. (Mus musculus) PubMed
6700.
Results identify a novel signaling process governing G-protein-coupled cAMP signal transduction-opposing actions of the phosphatase calcineurin and the CK1/GSK3beta protein kinases on the phosphodegron-dependent degradation of PDE4D [PDE4D]. (Mus musculus) PubMed
6701.
DnaA utilizes at least two different oligomeric conformations for engaging single- and double-stranded DNA. [DnaA] (Mus musculus) PubMed
6702.
Trigger factor appears to employ multiple mechanisms to interact with a wide range of substrate proteins. [TF] (Mus musculus) PubMed
6703.
crystal structure of an amino-terminally truncated form of IpgC [IpgC] (Mus musculus) PubMed
6704.
that CTR1 expression was inhibited at the transcriptional level through direct inhibition of the Mac1 transcriptional activator.[Mac1] (Mus musculus) PubMed
6705.
RAVL1 participates in the maintenance of brassinosteroid homeostasis by enhancing the expression of BRI1 and several BR biosynthetic genes. (Mus musculus) PubMed
6706.
model revealed unique structural features of TaOMT2 which permit the stepwise methylation of tricetin[-methyltransferase (TaOMT2)] (Mus musculus) PubMed
6707.
expression of Y53A-actin, which does not affect cell growth, phagocytosis, or pinocytosis, inhibits the formation of head-to-tail cell streams during cAMP-induced aggregation, although individual amoebae chemotax normally [actin] (Mus musculus) PubMed
6708.
the work presented here shows that are differences between Dad1 from C. albicans and S. cerevisiae. [Dad1] (Mus musculus) PubMed
6709.
a novel post-translationally modified hemolytic toxin, clostridiolysin S [clostridiolysin S] (Mus musculus) PubMed
6710.
a new, second gene encoding a plastid located glutamine synthetase (GS2) in M. truncatula [glutamine synthetase 2b] (Mus musculus) PubMed
6711.
ValR, a homolog to V. harveyi LuxR, may control biofilm formation by regulating flagellar biosynthesis and affect the expression of the genes involved in colony phase variation in V. alginolyticus. [ValR] (Mus musculus) PubMed
6712.
DnaK2 is the most abundant DnaK protein in Synechocystis, and only the expression of dnaK2 is highly up-regulated under diverse stress conditions. [DnaK2] (Mus musculus) PubMed
6713.
These results indicate that ClpP enhances the formation of Staphylococcus epidermidis biofilms by degrading Spx, a negative regulator of biofilm formation.[Spx] (Mus musculus) PubMed
6714.
The equine homologues of OS-9 and PSMC3 were cloned and their interactions with equine infectious anemia virus S2 protein confirmed using co-immunoprecipitation assays.[S2] (Mus musculus) PubMed
6715.
BC12 encodes a kinesin-4 protein that shows microtubule-dependent ATPase activity. Mutation results in altered mechanical strength and reduced plant height. [BC12] (Mus musculus) PubMed
6716.
STb and AIDA-I is associated with the pathogenicity of enterotoxigenic Escherichia coli. [AIDA-I] (Mus musculus) PubMed
6717.
The authors identified PavB as colonization factor.[PavB] (Mus musculus) PubMed
6718.
Sorbic acid decarboxylation also requires the activity of a putative 4-hydroxybenzoic acid decarboxylase, encoded by a gene termed ohbA1, and a putative transcription factor, sorbic acid decarboxylase regulator, encoded by sdrA.[ohbA1 & sdrA] (Mus musculus) PubMed
6719.
A gene (CYG56) coding for a nitric oxide (NO)-dependent guanylate cyclase (GC) was interrupted in a mutant defective in repression of NIA1 and NR in response to ammonium.[sGC, NIA1] (Mus musculus) PubMed
6720.
While gene disruption reveals that ROP13 is not essential for growth in fibroblasts in vitro or for virulence in vivo, the authors find that ROP13 is a soluble effector protein that can access the cytoplasm of host cells.[ROP13] (Mus musculus) PubMed
6721.
arf3a transcripts hyperaccumulate but remain abaxialized in rgd2 mutant apices, revealing that trans-acting small interfering RNA -siARF function is not required for arf3a polarization.[rgd2] (Mus musculus) PubMed
6722.
STR heterodimerizes with STR2, and the resulting transporter is located in the peri-arbuscular membrane where its activity is required for arbuscule development and consequently a functional arbuscular mycorrhizal symbiosis.[STE, STR2] (Mus musculus) PubMed
6723.
The bacterial risk factor iceA2 seems an important predictor of severe histological changes in chronic gastritis, separately or in combination with host genetic factors in the Venezuelan population. (Mus musculus) PubMed
6724.
Results demonstrate that trypanosomal tRNA(Sec), in contrast to its human counterpart, is transcribed by Pol-II (tRNASec). (Mus musculus) PubMed
6725.
mitotic division, the M-phase-promoting factor amplification loop is constantly active throughout the cell cycle, and that correct regulation of PP2A activity is essential to promote normal mitosis [MPF,Greatwall]. (Mus musculus) PubMed
6726.
Hpk2 and Rrp2 constitute a functional two-component system that contributes to environmental sensing [Hpk2, Rrp2] (Mus musculus) PubMed
6727.
The authors found that Helicobacter pylori CheZ (CheZ(HP)) efficiently dephosphorylates CheY(HP) and CheAY and has additional weak activity on CheV2.[CheZ] (Mus musculus) PubMed
6728.
the first crystal structure of a RihA bound to a competitive inhibitor [RihA] (Mus musculus) PubMed
6729.
The diheme cytochrome c(4) from Vibrio cholerae is a natural electron donor to the respiratory cbb(3) oxygen reductase (Mus musculus) PubMed
The Scll of M41-type GAS specifically binds LDL. [scl1] (Mus musculus) PubMed
6732.
Mdm36-dependent formation of cell cortex anchors is required for the generation of tension on mitochondrial membranes to promote mitochondrial fission by Dnm1.[Mdm36] (Mus musculus) PubMed
6733.
Chs3 and Ste24 form a complex in the endoplasmic reticulum that facilitates protease action on prenylated Chs4, a known activator of Chs3 with a C-terminal CaaX motif, leading to a more efficient localization of Chs3 at the plasma membrane.[Ste24] (Mus musculus) PubMed
6734.
An MEN mutant, cdc15-2, though competent in activating the spindle assembly checkpoint when exposed to Nocodazole, mis-segregated chromosomes during recovery from spindle checkpoint activation.[cdc 15-2] (Mus musculus) PubMed
6735.
Data suggest that Bat3 either modulates the Sec61beta/TRC40 pathway in higher eukaryotes or provides an alternative fate for newly synthesised tail-anchored proteins [Bat3]. (Mus musculus) PubMed
6736.
Saccharomyces cerevisiae gamma-TuSC forms rings even in the absence of other gamma-TuRC components [Tub4= gamma tubulin] (Mus musculus) PubMed
6737.
Sequence polymorphisms in LMP2A from northern Chinese EBV-associated gastric carcinoma patients, nasopharyngeal carcinoma and healthy donors shows variations in the LMP2A gene reveals classifiable sequence polymorphisms in exon 1 and exons 2-8. [LMP2A] (Mus musculus) PubMed
6738.
These findings demonstrate that co-mutation of amino acid residues at multiple positions in the NS1 protein can increase the pathogenicity of influenza virus in mice. (Mus musculus) PubMed
6739.
Mapping tests further demonstrated that aa 22-53 in the N-terminal region of H5N1 virus NS2 and the glycine-leucine-phenylalanine-glycine (GLFG) repeat domain (aa 1-511) of human Nup98 are crucial for the interaction of these two proteins. (Mus musculus) PubMed
6740.
[zinc-binding protein; Z-protein] structural studies on zinc-binding protein: ligand binding to C-terminal RING domain (Mus musculus) PubMed
6741.
[OsChia1b, class I chitinase, RCC2] crystal structure of full-length OsChia1b at 2.00-Angstrom resolution; docking simulation with tri-N-acetylchitotriose (Mus musculus) PubMed
6742.
Deletion of the gene encoding the gamma-butyrolactone receptor homologue ScbR2 led to the discovery of a yellow pigment and an antibiotic compound. [ScbR2] (Mus musculus) PubMed
6743.
The X-ray crystallographic analyses of apo- and complexed MalX illuminate the protein's specificity for the degradation products of glycogen and its striking ability to recognize the helical structure of the ligand.[MalX] (Mus musculus) PubMed
6744.
The hemolysin was stable up to 40 degrees C. Only partial activity remained at 50 and 60 degrees C. [hemolysin] (Mus musculus) PubMed
6745.
Functions of isoamylase-type starch-debranching enzyme (ISA) proteins and complexes in maize (Zea mays) endosperm were characterized.[ISA1, ISA2] (Mus musculus) PubMed
6746.
Deletion of atg8 abolished autophagosome accumulation in the vacuoles of carbon-starved cells and drastically reduced the survival of U. maydisDeltaatg8 mutant strains during these conditions. [atg8] (Mus musculus) PubMed
6747.
A highly conserved nuclear-encoded cGTPase of likely prokaryotic origin is essential for proper chloroplast ribosome assembly and/or translation in plants.[NOA1] (Mus musculus) PubMed
6748.
Os03g22780, renamed as OsDVR, encodes a functional DVR in rice.[DVR] (Mus musculus) PubMed
6749.
novel phosphoribosyltransferase transition states [Orotate Phosphoribosyltransferase] (Mus musculus) PubMed
6750.
BmPLCbeta1, BmGq1, and unexpectedly, BmPLCgamma, are part of the PBAN signal transduction cascade.[Gq1, PLcbeta1] (Mus musculus) PubMed
6751.
The authors showed that both ssl5 and ssl8 were induced by Sae and repressed by Agr, suggesting that Sae and Agr are the positive and the negative regulators, respectively, of these two ssl genes.[ssl8 & Agr] (Mus musculus) PubMed
6752.
Mouse angiogenin inhibitor 1 interacts with hylA of Streptococcus suis. [hylA] (Mus musculus) PubMed
6753.
Ltn1 is predominantly associated with ribosomes, and it marks nascent non-stop proteins with ubiquitin to signal their proteasomal degradation [Ltn1] (Mus musculus) PubMed
6754.
By yeast two-hybrid assay, the authors found that the capsid protein (CA) of bovine immunodeficiency virus interacted with the dynein light-chain component LC8.[capsid protein] (Mus musculus) PubMed
6755.
FINE CULM1 (FC1) partially works downstream of strigolactones to inhibit axillary bud outgrowth. [FC1] (Mus musculus) PubMed
6756.
The findings suggest that RcsFCDB activation in response to CAMP-induced membrane disorder is a result of a change in structure or availability of RcsF to the IM signaling constituents of the Rcs phosphorelay. (Mus musculus) PubMed
6757.
Data revealed that OdhA specifically catalyzes the E1 and E2 reaction to convert 2-oxoglutarate to succinyl-coenzyme A (CoA) but fully relies on the lipoyl residues provided by AceF involved in the reactions to convert pyruvate to acetyl-CoA.[OdhA] (Mus musculus) PubMed
6758.
Data conclude that the StyA1/StyA2B system represents a novel type of multifunctional flavoprotein monooxygenase. [StyA1] (Mus musculus) PubMed
6759.
The authors found that the rodent malaria parasite orthologue, Plasmodium berghei hexose transporter (PbHT) gene, was similarly refractory to knockout attempts, indicating it's essentiality.[PbHT] (Mus musculus) PubMed
6760.
Heterologous expression of the Aspergillus fumigatus cafB, and Aspergillus nidulans canA and canB genes completely rescued the high CO(2)-requiring phenotype of a Saccharomyces cerevisiae Deltance103 mutant.[cafB] (Mus musculus) PubMed
6761.
Heterologous expression of the Aspergillus fumigatus cafB, and Aspergillus nidulans canA and canB genes completely rescued the high CO(2)-requiring phenotype of a Saccharomyces cerevisiae Deltance103 mutant.[canA & canB] (Mus musculus) PubMed
6762.
Based on these data, the authors propose that POLIB performs an essential role at the core of the minicircle replication machinery.[POLIB] (Mus musculus) PubMed
6763.
These data indicate that Arl2 has a fundamentally conserved role in trypanosome microtubule biogenesis that correlates with alpha-tubulin acetylation.[Arl2] (Mus musculus) PubMed
6764.
dupA promotes duodenal ulceration in some populations and GU and GC in others. This is typical of other virulence factors, such as cagA. Hence, it was concluded that the H. pylori virulence factor, dupA, is a true virulence factor.[dupA](Meta-Analysis) (Mus musculus) PubMed
6765.
V. vulnificus produce outer membrane vesicles that can induce host cell death and this process is mediated by VvhA. [VvhA] (Mus musculus) PubMed
6766.
Analysis of protein interactions showed that K179A, K180A, and K221A substitutions of classical swine fever virus core protein disrupt core-SUMO-1 binding, while K220A substitution precludes core-UBC9 binding.[core protein] (Mus musculus) PubMed
6767.
The expression of the spliced form of YlHAC1 mRNA in the wild-type andDeltaYlhac1 strains resulted in an increased resistance to DTT, thereby indicating that the spliced form is translated into a functional YlHac1p.[HAC1] (Mus musculus) PubMed
6768.
Overexpression of ZmWRI1 results in an oil increase similar to overexpression of ZmLEC1 without affecting germination, seedling growth, or grain yield.[ZmWRI1] (Mus musculus) PubMed
6769.
Expression of Bs1 is tightly controlled and occurs during a narrow developmental window in early ear development.[Bs1] (Mus musculus) PubMed
6770.
sequence, linkage, association and expression analyses collectively showed that the two maize genes represent chromosomal duplicates, which function to control some of the phenotypic variation for kernel size and weight [ZmGW2-CHR4 and ZmGW2-CHR5] (Mus musculus) PubMed
6771.
expression of orfH79 in mitochondria impairs mitochondrial function, which affects the development of both male gametophytes and the roots of CMS-HL rice [orfH79; CMS-HL line] (Mus musculus) PubMed
6772.
a gene encoding a nucleotide binding site (NBS) and leucine rich repeat (LRR) domain-containing (NBS-LRR) protein encodes Pish, which confers resistance against races of Magnaporthe oryzae containing avrPish (Mus musculus) PubMed
6773.
the first report that the cholesterol binding ability may directly correlate with AeSCP-2's in vivo function in aiding the uptake of cholesterol (Mus musculus) PubMed
6774.
promiscuous TtHICDH was evolved into an enzyme showing distinct IPMDH activity by directed evolution using a DNA-shuffling technique[homoisocitrate dehydrogenase ] (Mus musculus) PubMed
6775.
BiP binding to Ire1 serves to desensitize Ire1 to low levels of stress and promotes its deactivation when favorable folding conditions are restored to the endoplasmic reticulum.[Ire1, BiP] (Mus musculus) PubMed
6776.
The finding that both mitochondrial AAC proteins and the vacuolar Pep4p interfere with mitochondrial degradation suggests a complex regulation and interplay between mitochondria and the vacuole in yeast programmed cell death.[AAC] (Mus musculus) PubMed
6777.
expressed in the ovary throughout early fetal stages to adulthood [BMP1] (Mus musculus) PubMed
6778.
Group B Streptococcus with decreased CovR function show a dramatic increase in their ability to cause bloodstream infections, activate innate immune signalling pathways and penetrate the blood-brain barrier. [CovR] (Mus musculus) PubMed
6779.
Because of the role of ARD in the methionine salvage pathway, these results suggest that TaARD (aci-reductone-dioxygenase) may be involved in ethylene synthesis and ethylene signaling in response to biotic and abiotic stresses. (Mus musculus) PubMed
6780.
Expressed chitinases from S. marcescens GEI by recombinant Escherichia coli showed pathogenicity against Varroa destructor in the laboratory [ChiA; ChiB; ChiC1] (Mus musculus) PubMed
6781.
These studies provide clear evidence that SpyCEP is necessary and sufficient for systemic bacterial dissemination from a soft tissue focus in this model and also underlies dissemination in the respiratory tract.[CEP] (Mus musculus) PubMed
6782.
BmTCTPk may play an important role during the developmental transition from pupa to imago.[TCTPk] (Mus musculus) PubMed
6783.
Overexpression of a number of protein kinases in the rac1, dck1 and lmo1 deletion mutants indicates that Rac1, Dck1 and Lmo1 function upstream of the mitogen-activated protein kinases Cek1 and Mkc1.[ Rac1, Dck1 and Lmo1] (Mus musculus) PubMed
6784.
These data show that in Plasmodium falciparum the mitochondrion serves as a dynamic Ca(2+) store and that PfCHA functions as a Ca(2+) efflux system expelling excess Ca(2+) from the mitochondrion.[CHA] (Mus musculus) PubMed
6785.
The authors demonstrate that a parasite cathepsin protease, TgCPL, occupies a newly recognized vacuolar compartment (VAC) that undergoes dynamic fragmentation during Toxoplasma gondii replication.[CPL] (Mus musculus) PubMed
6786.
The study presented here develops high-resolution genetic and physical maps in an effort to identify the XiR1 gene(s).[XiR1] (Mus musculus) PubMed
6787.
These results demonstrate the involvement of rnjB in E. faecalis pilin gene expression and provide insight into a novel mechanism of regulation of pilus production in Gram-positive pathogens.[rnjB] (Mus musculus) PubMed
6788.
Study conclude LukGH is a novel two-component leukotoxin with cytolytic activity toward neutrophils, and thus potentially contributes to S. aureus virulence. [LukG] (Mus musculus) PubMed
6789.
Lipophorin (Lp) and vitellogenin (Vg), two nutrient transport proteins, reduce the parasite-killing efficiency of the antiparasitic factor TEP1.[Vitellogenin] (Mus musculus) PubMed
6790.
It is proposed that WNV gpE can interact specifically with two cellular proteins (laminin-binding protein and alphaVbeta3 integrin) during virus entry (glycoprotein E). (Mus musculus) PubMed
6791.
The Si influx transporter OsNIP2;1 is permeable to selenite. [NIP2;1] (Mus musculus) PubMed
6792.
The formation of myosin filaments through the tail region has only a slight effect on binding to F-actin but has significant effects on the cortical localization of myosin II.[Myosin, Actin] (Mus musculus) PubMed
6793.
DTH8 suppressed rice flowering under long day conditions, and plays an important role in the regulation of plant height and yield potential. [DTH8] (Mus musculus) PubMed
6794.
The samples analyzed corresponded to SAG2 type I isolates, and they differ from classic SAG2 type I by genetic polymorphisms.[SAG2] (Mus musculus) PubMed
6795.
Sialostatin L2 - but not sialostatin L - facilitates the growth of B. burgdorferi in murine skin. [sialostatin L2] (Mus musculus) PubMed
6796.
Results indicate that SMAD1 signaling is active in culture as well as in blastula embryos, but STAT3 is inactive and can thus not be involved in pluripotency control of blastula cells or their derived pluripotent in vitro counterparts. (Mus musculus) PubMed
6797.
part of Xenopus Dead end-localization elements critical for somatic RNA clearance exhibits homology to zebrafish nanos1 and appears to be targeted by Xenopus miR-18 for somatic mRNA clearance. [miR-18] (Mus musculus) PubMed
6798.
The effects of heat stress and hypothyroidism on reproductive hormones and vasoactive intestinal polypeptide (VIP)-immunoreactive cells in the hypothalamus in hens are reported.[VIP] (Mus musculus) PubMed
6799.
An external constant electric field is able to modify the secondary structure of a protein and induce a transition from a beta-sheet into a helix-like conformation.[gp120] (Mus musculus) PubMed
6800.
Gene knockout studies in the bloodstream form of the parasite indicate that the neutral sphingomyelinase is essential for growth and survival.[neutral sphingomyelinase] (Mus musculus) PubMed
6801.
CRA1 regulates lignin and flavonoid contents and, consequently, affects polar auxin transport and root growth. [CRA1] (Mus musculus) PubMed
6802.
OmpK gene cloned/expressed; DNA/protein sequences reported; sequence alignment/phylogenetic analysis among Vibrio proteins reported. OmpK protein is likely a genus-specific antigen for Vibrio species [OmpK] (Mus musculus) PubMed
6803.
Native Scl1 mediated group A Streptococcus adherence to ligand-coated glass cover slips and promoted GAS internalization into HEp-2 cells.[Scl1] (Mus musculus) PubMed
6804.
The authors found that EAP and Nptase also play a role in biofilm formation under iron-replete conditions in the presence of human serum.[Eap] (Mus musculus) PubMed
6805.
The HcpA pilin monomer of the HCP produced by EHEC O157:H7 is a potent inducer of IL-8 and TNF-alpha release [HCP] (Mus musculus) PubMed
6806.
a stepwise mechanism for the replacement of H2A with Htz1 in SWR1 complex[SWR1][H2A.Z] (Mus musculus) PubMed
6807.
Vpu protein does not affect the conformation of influenza A virus HA in acidic trans-Golgi compartment. [HA] (Mus musculus) PubMed
6808.
The blocking of complement receptor 3-related protein by antibodies before adherence affected the fitness of biofilm, which was not able to revitalize in the later stages.[complement receptor 3-related protein] (Mus musculus) PubMed
6809.
Structural and functional characterization of the ga-substituted ferredoxin from Synechocystis sp. PCC6803, a mimic of the native protein (Mus musculus) PubMed
6810.
HHV-6 glycoprotein Q1 is an essential gene for virus growth. [gQ1] (Mus musculus) PubMed
6811.
Age3p, a functional ortholog of GCS1, is required for hyphal growth [GCS1] (Mus musculus) PubMed
6812.
The authors provide the first experimental evidence of the function of the Candida albicans putative gene orf19.7626 as an eIF4E protein.[eIF4E] (Mus musculus) PubMed
6813.
These data establish a new role to EFG1 in affecting the drug susceptibilities of Candida albicans cells, independent of reactive oxygen species and known drug efflux mechanisms.[EFG1] (Mus musculus) PubMed
6814.
Age3p, a functional ortholog of GCS1, is required for hyphal growth [AGE3] (Mus musculus) PubMed
6815.
In Zygosaccharomyces rouxii, the loss of Fps1p compromised the use of acetamide and several other small amides as sources of nitrogen, an indication that these amides enter the cells of this yeast by passive diffusion through the Fps1p pore.[Fps1] (Mus musculus) PubMed
6816.
identification of a specific damage-dependent Mec1/Tel1 site of Slx4 phosphorylation, Thr 113, that is required for efficient cleavage of 3' non-homologous tails by Rad1-Rad10 [Mec1; TEl1; Slx4; Rad1; Rad10] (Mus musculus) PubMed
6817.
Loss of HNT3 in rad27Delta cells, which are deficient in long-patch base excision repair (LP-BER), resulted in synergistic sensitivity to H(2)O(2) and methylmethane sulfonate. [Rad27] (Mus musculus) PubMed
6818.
The ceKDM7A is a histone demethylase specific for H3K9me2 and H3K27me2, and the PHD finger binding to H3K4me3 guides the demethylation activity in vivo.(ceKDM7A proteins) (Mus musculus) PubMed
6819.
The ceKDM7A is recruited to the promoter to demethylate H3K9me2 and H3K27me2 and activate gene expression through the binding of the PHD domain to H3K4me3. (ceKDM7A protein) (Mus musculus) PubMed
6820.
ACP adopts a unique conformation for each intermediate driven by changes in the internal fatty acid binding pocket [ACP] (Mus musculus) PubMed
6821.
These results suggest that immediate-early protein 3 (IE3) acts as a key protein for viral DNA replication by establishing pre-replication domains via recruitment of the required viral and cellular proteins, and by reducing host defences.[IE3] (Mus musculus) PubMed
6822.
LPD1 was required for filamentous growth under a serum-containing hyphal-inducing condition. [Lpd1] (Mus musculus) PubMed
6823.
The isolated virus lacking an intact transcriptional activator C2 protein is the causes of the cotton leaf curl disease.[C2] (Mus musculus) PubMed
6824.
daf-2(e1370) and daf-2(e1370);pept-1(lg601) animals were compared with a focus on genes that showed significantly higher changes in expression levels in daf-2;pept-1 than in daf-2.[pept-1] (Mus musculus) PubMed
6825.
crystals of isopropylmalate dehydrogenase were grown in the presence of various combinations of substrate and/or cofactors[isopropylmalate dehydrogenase ] (Mus musculus) PubMed
6826.
Analysis of the products demonstrates unambiguously that Ari1p directs hydride transfer from the si face of NADPH to the re face of furfural.[Ari1] (Mus musculus) PubMed
6827.
FeoA is found to adopt a unique dimer cross-linked by two zinc ions and six anions (chloride ions). [ FeoA ] (Mus musculus) PubMed
6828.
This study identifies HPA-1 and HPA-2 as novel negative regulators of EGF signaling and constitutes the first report of EGF signaling as a major pathway for healthy aging.[EGFR, PLC gamma, IP3R] (Mus musculus) PubMed
6829.
formation of the 'glutamine transamidosome' from the bacterium Thermotoga maritima, consisting of tRNA(Gln), GluRS and the heterotrimeric amidotransferase GatCAB, and its crystal structure at 3.35 A resolution [GluRS; GatC&A&B] (Mus musculus) PubMed
6830.
These results support a model whereby transcription factors SBF and MBF may be differentially activated by Cln3.[Cln3] (Mus musculus) PubMed
6831.
These data indicate that HBZ of human T-cell leukemia virus type 1 activates Dkk1 expression through its interaction with p300/CBP.[HBZ] (Mus musculus) PubMed
6832.
Cryptococcus neoformans CLN1 is able to complement Saccharomyces cerevisiae G1 cyclin deficiency, demonstrating that it is a G1 cyclin homologue.[CLN1] (Mus musculus) PubMed
6833.
Complementation and epistasis analyses reveal that it is the repression of exsA expression, but not exsB expression, by LuxR that is responsible for the QS-mediated repression of type 3 secretion system genes at high cell density.[LuxR & ExsA] (Mus musculus) PubMed
6834.
Sorting of transmembrane GRA6 to the host vacuole is driven by its N-terminal hydrophilic domain. [GRA6] (Mus musculus) PubMed
6835.
These findings reveal an important role for eIF4H/drr-2 in the TOR-mediated longevity responses to dietary restriction.[Drr-2, TOR] (Mus musculus) PubMed
6836.
HOS2 and HDA1 have opposite roles in the regulation of hyphal formation [HOS2][HDA1] (Mus musculus) PubMed
6837.
role of PPK2 as a novel pathogenicity determinant that is critical for C. jejuni survival, adaptation, and persistence in the host environments [PPK2] (Mus musculus) PubMed
6838.
MORN1 is required for basal complex assembly [MORN1] (Mus musculus) PubMed
6839.
Gpa2 and Pde1 are responsible for down-regulation of cAMP signalling induced by glucose addition. [Gpa2 and Pde1] (Mus musculus) PubMed
6840.
caspase-1 activation by SopE and the type iii secretion system-1 [SopE][T1] (Mus musculus) PubMed
6841.
VPA0450 is an inositol polyphosphate 5-phosphatase that hydrolyzed D5 phosphate from plasma membrane phospholipid phosphatidylinositol 4,5-bisphosphate; it disrupted cytoskeletal binding sites on inner membrane surface; caused membrane blebbing[VPA0450] (Mus musculus) PubMed
6842.
findings provide evidence that 5'-end capping is not a constitutive process that necessarily always proceeds to completion and demonstrates that Rai1 has an essential role in clearing mRNAs with aberrant 5'-end caps[Rai1] (Mus musculus) PubMed
6843.
Our results indicate that interactions between p27 and p88 replicase proteins play an essential role in viral RNA replication and in suppressing RNA silencing via the 480-kDa replicase complex assembly.[p27, p88] (Mus musculus) PubMed
6844.
The detection of tet(c) positive E. coli was found to be difficult using the current for tetracycline resistance.[TetC] (Mus musculus) PubMed
6845.
These results indicate that virA plays an important role in the pathogenicity of Streptococcus suis serotype 2.[virA] (Mus musculus) PubMed
6846.
The C-terminal part of the Nce102 protein is necessary for localization of both Nce102 itself and Can1 to membrane compartment of arginine permease Can1 and also for the formation of furrow-like membrane invaginations.[Nce102] (Mus musculus) PubMed
6847.
The Uga3 and Uga35/Dal81 transcription factors bind to the UGA4 promoter in a gamma-aminobutyric acid-dependent manner and that this binding is impaired by the presence of leucine.[Uga3, Uga35, Uga4] (Mus musculus) PubMed
6848.
This study demonstrates the importance of chromatin remodeling by the conserved histone acetyltransferase Gcn5 in regulating the expression of specific genes that allow C. neoformans to respond appropriately to the human host.[Gcn5] (Mus musculus) PubMed
6849.
These results demonstrate that the endosomal sorting complex required for transport pathway has Rim101-independent functions for C. albicans virulence.[Rim101] (Mus musculus) PubMed
6850.
These results suggest no significant role of EhROM1 in complement resistance but unexpected roles in parasite adhesion and phagocytosis.[EhROM1] (Mus musculus) PubMed
6851.
These results indicate that the expression of AQP4 and Kir4.1 channels on Muller cells is associated with the changes in ocular volume seen during the induction of refractive errors.[Kir1.4] (Mus musculus) PubMed
6852.
crystal structure of FucP at 3.1 A resolution, which shows that it contains an outward-open, amphipathic cavity [FucP] (Mus musculus) PubMed
6853.
The involvement of glycoprotein G in membrane fusion is investigated through electron microscopy. (Mus musculus) PubMed
6854.
These data suggest a putative role of DNA polymerase A in translesion DNA synthesis in Entamoeba histolytica.[DNA polymerase A] (Mus musculus) PubMed
These results indicate that oxidized LolA stably binds to LolCDE, which causes strong envelope stress [LolA] (Mus musculus) PubMed
6857.
The role of small noncoding RNAs in the translation and stability of rpoS mRNA during expression is reported [rpoS] (Mus musculus) PubMed
6858.
These results suggest that the toxT promoter recognition function provided by ToxR can facilitate the interaction of TcpP with the toxT promoter. [TcpP; ToxT; ToxR] (Mus musculus) PubMed
6859.
The results show that the native lipoprotein SitC-His specifically colocalizes with murine TLR2, is internalized by host cells, induces proinflammatory cytokines, and triggers intracellular accumulation of TLR2.[SitC] (Mus musculus) PubMed
6860.
This report characterizes a a genetic locus unique to staphylococci called rsr that has a role in repressing teh virulence regulator agr.[RSR; AGR] (Mus musculus) PubMed
6861.
The role of the SasG surface protein in bacterial adhesion and biofilm formation is reported.[SasG] (Mus musculus) PubMed
6862.
Osmotic induction of transcription of the sigHp2 promoter that is specifically recognized by RNA polymerase containing sigma(H) was absent in an S. coelicolor bldG mutant, indicating a role of BldG in sigma(H) activation.[sigma H] (Mus musculus) PubMed
6863.
The removal of Dig1 results in a specific increase in intrinsic and extrinsic noise in the transcriptional outputs of the mating pathway. The dig1Delta cells, Ste12 relocalizes from the nucleoplasmic distribution seen in wild-type cells. (Mus musculus) PubMed
6864.
We report LT-IIc, a new type II heat labile enterotoxin (HLT) encoded from an enterotoxigenic E. coli (ETEC) strain isolated from an avian host. [LT-IIC] (Mus musculus) PubMed
6865.
Gelatinase (GelE) is the principal mediator of pathogenesis in endocarditis. [GelE] (Mus musculus) PubMed
6866.
Telomerase activity in the lens epithelial cells of posterior capsule opacification is lower than that in the equator capsule. [Telomerase] (Mus musculus) PubMed
6867.
Mutant strains deficient in nadA, nadC, or nadS required exogenous nicotinate for growth. NdnR acts as a transcriptional repressor of NAD de novo biosynthesis genes.[nadC, nadS and NdnR] (Mus musculus) PubMed
6868.
We report the identification and activities of three novel superantigen-encoding genes in Streptococcus equi subsp. zooepidemicus: szeF, szeN, and szeP.[szeF, szeN, szeP] (Mus musculus) PubMed
6869.
The results indicate that the genetic blockage of starch synthesis in the sta6 and sta7-10 mutants increases the accumulation of lipids on a cellular basis during nitrogen deprivation.[sta7-10] (Mus musculus) PubMed
6870.
open reading frame of flaC gene contains 1155 bp and the putative protein consists of 384 amino acid residues[FlaC] (Mus musculus) PubMed
6871.
[2 genes, Coa3 & Cox14]Coa3 and Cox14 are required for Mss51 association with newly synthesized Cox1. (Mus musculus) PubMed
6872.
We report a mechanism employed by Fusobacterium nucleatum for cell death induction of human lymphocytes via two outer membrane proteins (OMPs), Fap2 and RadD, which share regions homologous to autotransporter secretion systems.[Fap2,RadD] (Mus musculus) PubMed
6873.
Zip1-S75 phosphorylation does not alter chromosome synapsis or double-strand break repair, indicating that Mec1 separates centromere pairing from the other functions of Zip1.[Mec1, PP4] (Mus musculus) PubMed
6874.
These results show that recognition of C. albicans by S. gordonii involves Als3 protein-SspB protein interaction, defining a novel mechanism in fungal-bacterial communication. (Mus musculus) PubMed
6875.
A functional analysis of two major homologues of the velvet complex in P. chrysogenum, velA (PcvelA) and PclaeA, is provided.[PcvelA, PclaeA] (Mus musculus) PubMed
6876.
Pat1a is a translational repressor in oocytes in a CPEB-containing complex, and Pat1b is a component of P-bodies in somatic cells.[Pat1a and Pat1b] (Mus musculus) PubMed
6877.
The colicin rRNase domain binds the A site of the decoding center in the 70S ribosome & cleaves the 16S rRNA between A1493 & G1494 via the concerted action of conserved residues Glu62 & His58 of the cytotoxic domain of colicin E3. Colicin E3. (Mus musculus) PubMed
6878.
19-A resolution shows a dodecameric structure with a central channel having a closed periplasmic gate. The periplasmic domain forms a vestibule with a conserved constriction. It binds a pentameric exoprotein & the tip of the T2SS pseudopilus. GspD. (Mus musculus) PubMed
6879.
The N-terminal S-layer-homologous domain of the Mep45 outer membrane protein was found to be protruding into the periplasmic space and was responsible for binding to peptidoglycan.[Mep45] (Mus musculus) PubMed
6880.
show that the yeast Acr3p mediates not only high-level resistance to arsenite but also moderate tolerance to antimonite[Acr3p] (Mus musculus) PubMed
6881.
Compartmentalization of NS1 within the cell contributes to the pathogenicity of avian influenza virus H7N1. [NS1] (Mus musculus) PubMed
6882.
In contrast to other characterized N1 neuraminidases, which are all members of group 1, 2009 H1N1 neuraminidase does not have a 150-cavity. (Mus musculus) PubMed
6883.
can be taken to imply that the TrwB transmembrane domain plays a regulatory role in its biological activity[TrwB] (Mus musculus) PubMed
6884.
Bovine foamy virus transactivator BTas interacts with cellular RelB to enhance viral transcription. [BTas] (Mus musculus) PubMed
6885.
findings show that GtrA, specifically binds the promoter of the matPQMAB operon, positively regulating its expression [GtrA] (Mus musculus) PubMed
6886.
Data show that chloramphenicol boiosynthetsis is catalyzed by the enzyme CmlA from an operon containing the genes for biosynthesis of L-PAPA and the nonribosomal peptide synthetase CmlP: [CmlA and CmlP] (Mus musculus) PubMed
6887.
Dom34 & GTP bind to Hbs1 with strong cooperativity. Dom34 acts as GTP-dissociation inhibitor. Conformational change in Dom34 occurs upon binding to Hbs1. Dom34-Hbs1 complex terminates translation & commits mRNAs to no-go decay.[Dom34, Hbs1] (Mus musculus) PubMed
6888.
Data identified the transcription factor Meis2 as one of the main targets of miR-204 function: [miR-204 and Meis2] (Mus musculus) PubMed
6889.
Injection of peptidoglycan-polysaccharide resulted in fever, increased concentrations of haptoglobin on the day of and the day after challenge, and decreased concentrations of progesterone on days 14 and 21.(haptoglobin, HP) (Mus musculus) PubMed
6890.
A direct relationship between ecto-ATPase activity and adhesion to host cells was observed. In these assays, inhibition of enzyme activity resulted in decreased levels of yeast adhesion to epithelial cells.[ecto-ATPase] (Mus musculus) PubMed
6891.
A new member of the Bombyx mori small heat shock protein family, BmHSP25.4 was cloned and characterized.[BmHSP25.4] (Mus musculus) PubMed
6892.
An E(z) homolog, EZH, in the green alga Chlamydomonas reinhardtii, was characterized to gain insight on the role of PRC2 in single celled organisms.[PRC2, EZH] (Mus musculus) PubMed
6893.
Both LIS-1 and the dynein heavy-chain DHC-1 are required for integrity of the actin cytoskeleton in C. elegans.[DHC-1] (Mus musculus) PubMed
6894.
BTEB1 activated the FGFR1 promoter via interaction with the Sp1-like binding site located at -59 bp within the FGFR1 promoter.[BTEB1] (Mus musculus) PubMed
6895.
Gain-of-function mutations in CgPDR1 contributed to the clinical azole resistance, but different mutations had various degrees of impact on the CgPDR1 target genes. [PDR1] (Mus musculus) PubMed
6896.
The observed post-translational mannosylation of polar tube protein PTP1 may be involved in the functional properties of the polar tube, including its adherence to host cells during penetration. [PTP1] (Mus musculus) PubMed
6897.
results suggest that Clp upregulates the gum operon by binding to two non-consensus sites [Clp] (Mus musculus) PubMed
These data support the critical role of residue 87 in the stability and folding of VIM-2. [VIM-2] (Mus musculus) PubMed
6900.
Our data show that BpeAB-OprB of Burkholderia pseudomallei 1026b is a multidrug efflux system which extrudes macrolides, fluoroquinolones, tetracyclines, acriflavine, and, to a lesser extent, chloramphenicol. [BpeA, BpeB, OprB] (Mus musculus) PubMed
6901.
The authors propose that the reduced virulence of the pga29 mutant is a consequence of altered surface properties, resulting in altered fungal recognition. (Mus musculus) PubMed
6902.
The authors used indirect immunofluorescence assays and immunoelectron microscopy to demonstrate that PfASP is localized in the neck of rhoptries and not in micronemes as previously described.[ASP] (Mus musculus) PubMed
6903.
Based on these results, Theileria parva SCOP likely plays an important role in NF-kappaB activation and apoptosis inhibition during Theileria infection.[SCOP] (Mus musculus) PubMed
6904.
These results show that bovine LEE-negative STEC strains possessed genes encoding virulence factors present in human LEE-negative STEC strains that are associated with disease. (Mus musculus) PubMed
6905.
The authors show that short N-terminal fragments (</=70 amino acids) from SepL are capable of targeting fusion proteins for secretion and translocation. (Mus musculus) PubMed
6906.
Results point to considerable potential for a role for FKBP16-1 in early chloroplast development, architecture of photosynthetic apparatus and plant development: [FKBP16-1] (Mus musculus) PubMed
6907.
TbRGG2 facilitates complete utilization of certain gRNAs.[RGG2] (Mus musculus) PubMed
6908.
Pichia pastoris mutant strains, defective in the enzyme pyruvate carboxylase, showed a pronounced growth defect on d-alanine, concomitant with a significant reduction in Dao1p activity relative to the wild-type control.[pyruvate carboxylase & Dao1] (Mus musculus) PubMed
6909.
Collectively, these results indicate that SarA binds directly to the tst promoter and that SarA plays a significant and direct role in the expression of tst.[SarA & tst] (Mus musculus) PubMed
6910.
Here, the authors evidence that K-bZIP affects IFN signaling, resulting in impaired IFN-stimulated genes expression.[K-bZIP] (Mus musculus) PubMed
6911.
Cadmium and phytochelatin levels were determined in protoplasts and vacuoles isolated from leaves of Nicotiana tabacum expressing either of two phytochelatin synthase genes, AtPCS1 and CePCS.[CePCS] (Mus musculus) PubMed
6912.
subtle differences between the TDO and IDO reactions [TDO] (Mus musculus) PubMed
6913.
The azole susceptibilities of the C. albicans isolates correlated well with ERG11 mutations. [ERG11] (Mus musculus) PubMed
6914.
The presence of 2 DNNND repeats in microsatellite ms4760 of pfnhe, a sodium hydrogen exchanger, was associated with reduced susceptibility to quinine, while 3 repeats were associated with restoration of susceptibility. [pfnhe] (Mus musculus) PubMed
6915.
Rabbit antithymocyte globulin alters the balance of regulatory to memory effector T cells posttransplant, providing an explanation for how it positively impacts transplant outcome. (antithymocyte globulin) (Mus musculus) PubMed
6916.
There is gain of function, i.e., multiple embryos in the seeds in the knockout mutant OsPE whereas its wild-type allele strictly controls single embryo per seed.[OsPE] (Mus musculus) PubMed
6917.
Polymorphism of host MMP-3, but noth dupA of Helicobacter pylori, correlate with the susceptibility to duodenal ulcer. [dupA] (Mus musculus) PubMed
6918.
CD1d is downregulated by the HPV16 E5 and HPV6 E5 protein. [E5] (Mus musculus) PubMed
6919.
AatA increased adherence of non-fimbriated E. coli K-12 strain to a chicken fibroblast cell line. [aatA] (Mus musculus) PubMed
6920.
VP23R mediates formation of virus-mock basement membrane to provide attaching sites for lymphatic endothelial cells. [VP23R] (Mus musculus) PubMed
6921.
Blue copper-binding protein, heat-stress transcription factor, WIR1A protein and ent-kaurene synthase transcripts were significantly involved in the resistance phenotype across all genotypes.[heat-stress transcription factor, WIR1A, ent-kaurene synthase] (Mus musculus) PubMed
6922.
These results show that over-expression of ZmPP2C2 in tobacco enhanced tolerance to cold stress, suggesting that this new gene, ZmPP2C2, may act as a positive regulator of cold resistance in plants.[PP2C2] (Mus musculus) PubMed
6923.
Presence of the IS1016-bexA deletion is associated with enhanced virulence in non-type b H. influenzae.[bexA] (Mus musculus) PubMed
6924.
The knockout mutant OsAPC6 interferes with the gibberellic acid signaling pathway leading to reduced height and cell size probably through ubiquitin-mediated proteolysis.[APC6] (Mus musculus) PubMed
6925.
PLD activity was able to hydrolyze a fluorescently labeled analog of phosphatidylcholine and was capable of performing the transphosphatidylation reaction characteristic of PLDs.[PLD] (Mus musculus) PubMed
6926.
In addition to its antifungal activity, AcAMP is the first fungal peptide exhibiting antibacterial activity against several Gram-positive and Gram-negative bacteria.[AcAMP] (Mus musculus) PubMed
6927.
Two dnai2 genes function either redundantly or distinctly in tissues possessing motile cilia.[jaodori] (Mus musculus) PubMed
6928.
The combined results suggest that 3C-mediated cleavage of PTB might be involved in down-regulation of viral translation to give way to subsequent viral genome replication.[3C] (Mus musculus) PubMed
6929.
The zinc site and protein structure in dimeric HypA are dependent on both the nickel binding status and the pH.[HypA] (Mus musculus) PubMed
6930.
structure of DspF, required for virulence of Erwinia amylovora, was modeled; study supports the significance of the predicted beta-sheet helix-binding groove in DspF chaperone function [DspF] (Mus musculus) PubMed
6931.
the reduced flavin mononucleotide coenzyme of IDI-2 functions as an acid/base catalyst [IDI-2] (Mus musculus) PubMed
6932.
Sialic acid transport and catabolism are cooperatively regulated by SiaR and CRP. [SiaR and CRP] (Mus musculus) PubMed
6933.
Gup1p strongly interferes with the capacity of cells to develop hyphae, to adhere, to invade, and to form biofilm. (Mus musculus) PubMed
6934.
Data determine the structures of the FK506 binding domain of Plasmodium vivax FKBP35 in unliganded form by NMR spectroscopy and in complex with FK506 by X-ray crystallography [FKBP35]. (Mus musculus) PubMed
6935.
Four new members of the SOCS family of molecules in rainbow trout (Oncorhynchus mykiss), CISH and SOCS6, 7 and 9, are described for the first time in this species[socs9] (Mus musculus) PubMed
6936.
PLB activity is involved in the process of adhesion, internalization and subsequent down-regulation of macrophage activation. [PLB] (Mus musculus) PubMed
6937.
LHbeta and LH-R mRNA expression might be involved in initial maturation events of gametes, at least in males [LHbeta] (Mus musculus) PubMed
6938.
Myo2p transport along actin cables may support a feedback loop by which delivery of astral microtubule plus ends sustains Kar9p polarized recruitment to the bud-ward spindle pole. [Kar9] (Mus musculus) PubMed
6939.
rabB Delta and rabA Delta mutations are synthetically lethal, demonstrating that Rab5-mediated establishment of endosomal identity is essential for A. nidulans.[RabB, rab5] (Mus musculus) PubMed
6940.
IFT70/CrDYF-1 is a canonical subunit of intraflagellar transport (IFT) particle complex B and strongly support the hypothesis that the IFT machinery has species- and tissue-specific variations with functional ramifications.[IFT70] (Mus musculus) PubMed
6941.
PotD plays a physiological role in the uptake of polyamines in vivo. [PotD] (Mus musculus) PubMed
6942.
To provide structural insights into how BoNT/D enters neuronal cells, the crystal structure of the receptor binding domain (S863-E1276) for this serotype (BoNT/D-HCR) was determined at 1.65A resolution.[BoNT/D] (Mus musculus) PubMed
6943.
The expression profiles of the MtTFIIS-like gene were compared to those of the MtTFIIS gene, encoding the canonical TFIIS protein, which was similarly up-regulated in response to both stresses; copper and polyethylene glycol.[TFIIS} (Mus musculus) PubMed
6944.
czrC is encoding zinc and cadmium resistance in CC398 MRSA isolates, and that it is widespread both in humans and animals. [czrC] (Mus musculus) PubMed
6945.
ScanProsite analysis of IAP4 amino acid sequence show that it contains a baculovirus Inhibitor of Apoptosis repeat (BIR) motif at the N-terminal portion from 18 to 61 amino acid and a Zinc finger RING motif near its C-terminus.[IAP4] (Mus musculus) PubMed
6946.
a novel transcriptional regulator that binds to the promoter region of succinyl-CoA synthetase (sucCD) in Corynebacterium glutamicum was identified. [SucR] (Mus musculus) PubMed
6947.
The structure of G-actin is presented in a form that is devoid of polymerization-deterring chemical modifications or binding partners, either of which may alter its conformation.[G-actin] (Mus musculus) PubMed
6948.
Coronin and Aip1 are important effectors that act together in maintaining the balance of actin polymerization and depolymerization in living cells.[Coronin and Aip1] (Mus musculus) PubMed
6949.
structural, dynamical, and thermodynamic properties of a model potassium channel [KcsA] (Mus musculus) PubMed
6950.
kaposin-B plays a key role in PROX1 upregulation during lymphatic reprogramming of blood vascular endothelial cells by KSHV (Mus musculus) PubMed
6951.
Rbf1 is a novel master regulator in a multilayered network of transcription factors that facilitates the complex regulatory traits of sexual and pathogenic development of Ustilago maydis (Mus musculus) PubMed
6952.
These findings provide direct genetic evidence that CTCF functions as a chromatin insulator that prevents the promiscuous transcription of surrounding genes and blocks the epigenetic silencing of an essential promoter, Qp, during EBV latent infection (Mus musculus) PubMed
6953.
vaccinia virus complement control protein domains 2 and 3 provide binding surface for factor I interaction, whereas domain 1 mediates dissociation of C2a and Bb from the classical and alternative pathway C3 convertases, respectively. (Mus musculus) PubMed
6954.
the mechanism for Ca2+-dependent CPI-17 phosphorylation and its effect of G protein activation is investigated. (Mus musculus) PubMed
6955.
a novel chromatin factor, X non-disjunction factor 1 (xnd-1), is responsible for the global distribution of meiotic crossovers in C. elegans [xnd-1] (Mus musculus) PubMed
6956.
the exchange coupling constant in the type 3 center in a fully metalated oxidase [Fet3] (Mus musculus) PubMed
6957.
Gcn5 impacts genome integrity via multiple mechanisms, including nucleosome assembly.[Gcn5] (Mus musculus) PubMed
6958.
Localization of Sst2 to the projection prevents excess G-protein activation during the pheromone response.[Sst2] (Mus musculus) PubMed
6959.
The structure-function relationship of cohesin, an essential chromosome maintenance protein, is investigated by analyzing its collective dynamics and conformational flexibility.[cohesin] (Mus musculus) PubMed
6960.
Transcription elongation by bacteriophage T7 RNAP was quatified on small, circular DNA templates approximately 100 bp in size.[RNAP] (Mus musculus) PubMed
6961.
findings suggest that tricarboxylic acid cycle enzymes AcnA and SdhA were not controlled by RyhB; study provides evidence to delineate the unique RhyB gene regulation in S. oneidensis [RyhB] (Mus musculus) PubMed
6962.
An ecdysone receptor and Broad-Complex Z2 (BR-Z2) are required for maximal BMWCP10 expression in the wing disc of Bombyx mori. [BMWCP10] (Mus musculus) PubMed
6963.
Clb2-Cdk1 protects Swe1 from premature degradation until its Hsl1 mediated de-protection, which enables its Cdc5 mediated degradation.[Clb2, Cdh1, Swe1] (Mus musculus) PubMed
6964.
FXDY-11 associates with and may regulate Na+-K+-ATPase activity in the gill of Atlantic salmon. (Mus musculus) PubMed
6965.
HPP1 represents a novel type of peptide pheromone precursors, and is essential for male fertility. [HPP1] (Mus musculus) PubMed
6966.
Thoracic gunshot injury decreased Cx40 level and increased pulmonary vascular permeability, with a significant correlation between Cx40 staining intensity and vascular permeability. [Connexin 40] (Mus musculus) PubMed
6967.
The heterodimeric glycoprotein GP3 is a constituent of the insoluble extracellular matrix. The backbones of both GP3 subunits are encoded by the same gene. [GP3] (Mus musculus) PubMed
6968.
crystal structure of EF-Tu and aminoacyl-tRNA bound to the ribosome with a GTP analog, to 3.2 angstrom resolution; activated conformation is due to interaction of the catalytic histidine with A2662 of the sarcin-ricin loop of the 23S ribosomal RNA [EF-TU] (Mus musculus) PubMed
6969.
X-ray structure of the MATE transporter NorM from Vibrio cholerae determined to 3.65 A[NorM] (Mus musculus) PubMed
6970.
These results suggest that Sin catalytic activity and oligomerization state are tightly linked.[Sin] (Mus musculus) PubMed
6971.
The protein kinase Elm1 is an obligate regulator of the pindle position checkpoint, and this function requires localization of Elm1 to the bud neck. [ELM1 protein, S cerevisiae] (Mus musculus) PubMed
6972.
These data suggest that Toxoplasma gondii cyclophilin 18 recruits cells and enhances the growth of host cells at the site of infection for maintenance of the interaction between the parasite and host.[cyclophilin 18] (Mus musculus) PubMed
6973.
OsNSP1 and OsNSP2 fully restore the defects in root nodulation symbiosis of Lotus japonicus mutants. [OsNSP2] (Mus musculus) PubMed
6974.
OsNPR1 has a role in the reallocation of energy and resources during defense responses. (Mus musculus) PubMed
6975.
Mss116 stimulates group II intron folding through a multi-step process that involves electrostatic stabilization of early intermediates and ATP hydrolysis during the final stages of native state assembly [Mss116] (Mus musculus) PubMed
6976.
Data show that the mutant ferric-binding protein A (FbpA) isolated from H. influenzae strain DL63, retain significant iron-binding affinity regardless of the nature of the replacement amino acid: [FbpA] (Mus musculus) PubMed
6977.
Loss of OsJAG function results in maldevelopment of all floral organs, such as degenerated lemma and palea, elongated lodicules and deformed and sterile pistil. (Mus musculus) PubMed
6978.
These data support that Trypanosoma cruzi protein kinase A phosphorylates trans-sialidase super family members in vivo.[protein kinase A] (Mus musculus) PubMed
6979.
The plenty mutant exhibited a unique phenotype of moderate hypernodulation. [PLENTY] (Mus musculus) PubMed
6980.
expression of both trout (t) FoxP3a and tFoxP3b are detectable in all the 14 tissues examined without any significant difference except in muscle in which the expression of tFoxP3a was higher[ FoxP3a and FoxP3b ] (Mus musculus) PubMed
6981.
Abnormal accumulation of proglutelin in the esp2 mutant is caused by the deficiency of PDIL1-1. PDIL1-1 disrupts the accumulation and packaging of rice seed storage proteins. [PDIL1-1] (Mus musculus) PubMed
6982.
FbsB(C) was cloned, expressed and purified. Dot blot, Western blot and ELISA experiments carried out with the purified protein showed that FbsB C-terminal, FbsB(C) has the ability to bind to bovine fibrinogen.[FsbB] (Mus musculus) PubMed
6983.
Identified is a PWL2 allele gene, which was termed PWL2D, in a strain of M. grisea. [PWL2] (Mus musculus) PubMed
6984.
Data describe the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by structural and functional analysis of the U597C mutant. (Mus musculus) PubMed
6985.
OsDSG1 encodes a RING finger E3 ligase that negatively regulates OsABI3. [OsDSG1] (Mus musculus) PubMed
6986.
MtATB2 is a bZIP transcription factor regulated by sucrose and localized to vascular tissues and root and nodule apices. [ATB2] (Mus musculus) PubMed
6987.
These results suggest that plasma membrane sphingomyelin is required for targeting of Helicobacter pylori VacA to membrane rafts important for subsequent Cdc42-dependent pinocytic cellular entry.[VacA] (Mus musculus) PubMed
6988.
study describes the purification and antibacterial spectrum of E229DL, a cationic and highly hydrophobic member of the delta-lysin peptide family that exhibits relatively little hemolytic activity [E229DL] (Mus musculus) PubMed
TaCHP enhances stress tolerance via the promotion of CBF3 and DREB2A expression.[TaCHP] (Mus musculus) PubMed
6993.
This study showed that beta2-Adrenergic receptors and G-protein-coupled receptor kinase 2 in rabbit pleural mesothelium. (Mus musculus) PubMed
6994.
MpdA was expressed in both sporulating and nonsporulating mycelia, while mtdA was expressed only in sporulating mycelium. [Mpd, Mtd] (Mus musculus) PubMed
6995.
RNG1 is a small, low-complexity, detergent-insoluble protein that assembles at the apical polar ring very late in the process of daughter parasite replication[RNG1] (Mus musculus) PubMed
6996.
Differential filamentation is governed by of UME6 expression. [UME6] (Mus musculus) PubMed
6997.
Ancestral roles for Wnt9s in early patterning of neural/oral-pharyngeal ectoderm and mesendoderm derivatives.[Wnt9a protein, zebrafish] (Mus musculus) PubMed
6998.
The CPAF signal peptide-directed translocation of PhoA requires the Sec-dependent pathway. [CPAF] (Mus musculus) PubMed
6999.
From these results the authors propose that FliL could participate in the coupling of MotB with the flagellar rotor in an indirect fashion.[FliL] (Mus musculus) PubMed
7000.
A combination of proteomics and transcriptomics analyses revealed three wheat glycosyltransferase proteins as promising candidates involved in Glucuronoarabinoxylans synthesis in wheat. [TaGT43-4, TaGT47-13, and TaGT75-4] (Mus musculus) PubMed
7001.
Rcm-1(NCU06842), rco-1(NCU06205) and ham-5(NCU11925) were required for hyphal fusion. [ram-5 (NCU11925)] (Mus musculus) PubMed
Interaction of Rickettsia felis OmpB with Ixodes histone H2B facilitates the infection.[H2B] (Mus musculus) PubMed
7004.
The disruption of hpdR led to reduced production of calcium-dependent antibiotic.[hpdR] (Mus musculus) PubMed
7005.
PilA pilus of two Enterococcus faecium isolats eassembles at different temperatures. [PilA] (Mus musculus) PubMed
7006.
single nucleotide polymorphism in the erythrocyte binding-like 1 (ebl-1) gene [ebl-1] (Mus musculus) PubMed
7007.
A cis-acting mutation and duplication of the Cyp9m10 gene is associated with overexpression in pyrethroid resistant Culex quinquefasciatus. (Mus musculus) PubMed
7008.
CaGPI19 is required for normal morphology and cell wall architecture. [CaGPI19] (Mus musculus) PubMed
7009.
The formation of a complex between the denatured monomeric form of Phb and the dissociated forms of GroEL is detected during heating at 46 degrees C.[GroEL] (Mus musculus) PubMed
7010.
[Elongation Factor G; EF-G] crystal structure of apo EF-G at 1.9 A resolution; comparison to previously published crystal structure of Thermus thermophilus EF-G (Mus musculus) PubMed
7011.
PDF-1 and PDF-2 are peptide deformylase homologues. PDF-1 has some different enzymic properties compared with PDF from S. aureus. PDF-2 has no peptide deformylase activity. [PDF-1; PDF-2] (Mus musculus) PubMed
7012.
The crystal structures of a type 2 RNase H in complex with substrates containing a (5')RNA-DNA(3') junction, is reported.[RNase H2] (Mus musculus) PubMed
7013.
Cj1514 has a specific role in the biogenesis of formate dehydrogenase, but is not required for TMAO reductase activity. [Cj1514] (Mus musculus) PubMed
7014.
Dictyostelium requires PS for phagocytosis and cell-fate specification in a cell-autonomous manner, and show that regulation of phagocytosis requires an active gamma-secretase.[Presenilin, gamma secretase] (Mus musculus) PubMed
7015.
These data suggest that OsC6 plays a crucial role in the development of lipidic orbicules and pollen exine during anther development in rice.[OsC6] (Mus musculus) PubMed
7016.
Ume6 directs hyphal growth via a pathway involving Hgc1 protein. [Ume6, Hgc1] (Mus musculus) PubMed
7017.
Upc2 protein binds to two cis-acting elements in the promoter region and autoregulated the transcription of UPC2 gene. [UPC2] (Mus musculus) PubMed
7018.
This method may also discriminate trans-sialidase and trans-sialylation activities by running the assay in the absence of benzyl beta-d-Fuc-(1-->6)-alpha-d-GlcNAc. (Mus musculus) PubMed
7019.
[RrgA] two variants suggest that proper folding and structural arrangement are crucial to retain functionality and are cross-reactive and cross-protective (Mus musculus) PubMed
7020.
a role of Avt5p in cellular uptake of toxic Li+ [Avt5p] (Mus musculus) PubMed
7021.
Rad9 phosphorylation by DDK releases Rad9 from DNA damage sites to facilitate DNA repair.[Rad9, DDK] (Mus musculus) PubMed
7022.
an extracellular carbohydrate esterase (CcEst1) was cloned from the basidiomycete Coprinopsis cinerea [CcEst1] (Mus musculus) PubMed
7023.
The let-7 represses expression of regeneration-associated genes such as, ascl1a and lin-28 exhibit basal expression in the uninjured retina and let-7 may inhibit this expression to prevent premature Muller glia dedifferentiation.[let7 microRNA] (Mus musculus) PubMed
7024.
rbm-28 genetically interacts with the lin-4 developmental timing pathway and uncover a previously unrecognized role for lin-14 and lin-28 in coordinating organismal growth (Mus musculus) PubMed
7025.
miR-1 was found to be involved in the regulation of the chondrocytic phenotype and thus to play an important role in chondrocytes during the late stage of the differentiation process, maintaining the integrity of the cartilage tissue. [mir-1] (Mus musculus) PubMed
7026.
CagA suppresses pinocytic endocytosis and the cytotoxicity of VacA in gastric epithelial cells without affecting clathrin-dependent endocytosis.[CagA, VacA] (Mus musculus) PubMed
7027.
a quantitative measure of how a conformational equilibrium in BtuB is modified in the crystal environment [BtiB] (Mus musculus) PubMed
7028.
The RecA-induced deformation and the binding energetics are fine-tuned to ensure optimal sequence detection.[RecA] (Mus musculus) PubMed
7029.
thermodynamic parameters for binding of N-acetylglucosamine oligomers to ChiB of Serratia marcescens [ChiB] (Mus musculus) PubMed
7030.
IIA(Glc) of the sugar phosphotransferase system regulates the peptidase activity of a mammalian insulysin homolog in V. vulnificus.[IIA Glc] (Mus musculus) PubMed
7031.
This study emphasizes the importance of core genome-encoded toxins in community acquired staphylococcal skin infections caused by the methicillin resistant USA300 strain.[alpha toxin, delta toxin] (Mus musculus) PubMed
7032.
alpha-solenoid structures such as importin-beta may bridge the molecular gap between completely structured and intrinsically disordered proteins [Kap95p] (Mus musculus) PubMed
7033.
Rok1 protein level is regulated by pstream open reading frames [ROK1] (Mus musculus) PubMed
7034.
Mrc1 facilitates Mec1 phosphorylation of the S/T-Q motifs of chromatin-bound Mcm2-7 during S phase to activate replication.[Mec1, Mcm2, Mcm7, Cdc7] (Mus musculus) PubMed
7035.
Mutations that disrupt ubiquitin binding abrogate Doa1 function, demonstrating the importance of the interaction with ubiquitin.[Doa1] (Mus musculus) PubMed
7036.
Psh1 functions to prevent the mislocalization of Cse4.[Psh1, Cse4] (Mus musculus) PubMed
7037.
The Cse4 centromere targeting domain is a key regulator of its stability and helps Psh1 discriminate Cse4 from histone H3.[Psh1, Cse4] (Mus musculus) PubMed
7038.
Model for translocation and unwinding activities of NS3 helicase. The model predicts that the NS3 helicase actively unwinds duplex by reducing more than 50% the free energy that stabilizes base pairing/stacking.(NS3 helicase) (Mus musculus) PubMed
7039.
M2 functionally reconstituted in liposomes populates at least three different conformational states over a physiologically relevant pH range, with transition midpoints that are consistent with previously reported His37 pK(a) values[M2 protein] (Mus musculus) PubMed
7040.
The obtained results showed that PRRSV nsp1 could inhibit Poly(I:C)-induced IFN-beta promoter activity in MARC-145 cells by down-regulating the protein level of IRF-3 and inhibiting the phosphorylation of IRF-3.[nsp1] (Mus musculus) PubMed
7041.
Helix-turn-helix motifs and a flexible sequence of Rns are required for maximal activation of fimbrial gene expression. [Rns] (Mus musculus) PubMed
7042.
structural characterization of oxidation intermediates for AlkB demethylase [AlkB] (Mus musculus) PubMed
7043.
A conserved X-shaped crystallographic dimer stabilized by intermolecular interactions between the second PASTA subunits of each monomer is observed in the two crystal forms of Stk1.[Stk1] (Mus musculus) PubMed
7044.
The structures reveal an anchor-shaped substrate-binding cavity comprising a conserved hydrophobic box that clamps the nucleotide base, a buried phosphoryl binding site, and three solvent-filled pockets.[e (P4) phosphatase] (Mus musculus) PubMed
7045.
CYP93G2 as the first enzyme that channels flavanones to C-glycosylflavone biosynthesis in rice.[CYP93G2] (Mus musculus) PubMed
These studies reveal that Mxr1p specifically binds to promoter regions containing multiple 5'-CYCC-3' sequences, although all DNA sequences containing the 5'-CYCC-3' motif do not qualify as Mxr1p-binding sites.[Mxr1p] (Mus musculus) PubMed
7048.
the structure of the PcyA V225D-biliverdin IXalpha complex was determined to reveal that an unpredictable structural change occurred in the substrate-binding pocket as a result of only one mutation in a residue distant from the processing sites. [PcyA] (Mus musculus) PubMed
7049.
The Staphylococcus aureus autoinducer-2 (AI-2) producer protein LuxS is phosphorylated by the Ser/Thr kinase Stk1 at a unique position, Thr14, abrogating its enzymatic activity.[LuxS & Stk1] (Mus musculus) PubMed
7050.
Fim1p has a novel role as a positive actin-binding "selector" protein that promotes the access of other proteins to actin filaments by inhibiting Cdc8p. [2 genes, Fim1 and Cdc8] (Mus musculus) PubMed
7051.
The asymmetric CEH-36 expression promotes asymmetric ngn-1 and hlh-2 expression, which in turn induces asymmetric MI neurogenesis.[CEH-36, NGN-1, HLH-2] (Mus musculus) PubMed
7052.
study of the avian MYB/gga-miR-150 interaction shows a conservation of miR-150 target site functionality between chicken and zebrafish that does not extend to mammals [miR-150] (Mus musculus) PubMed
7053.
Missense mutations A184V, T265M, R275Q, and N276D, which are known to occur in TEM extended-spectrum beta-lactamases from clinical isolates, were identified as suppressors of TEM-1 protein stability defects.[TEM-1 beta-lactamase] (Mus musculus) PubMed
7054.
The assembly of the RFC.PCNA.DNA complex and its progression to holoenzyme upon addition of polymerase delta, was examined.[PCNA, RFC] (Mus musculus) PubMed
7055.
Ubiquitin signaling in Met4 is controlled by its tandem ubiquitin-binding domain regions.[Met4] (Mus musculus) PubMed
7056.
Residue 221 of NS1 was identified to be a new key residue involved in the C-terminal nuclear localization signal (NLS) and nucleolar localization signal (NoLS) of NS1 from A/Sydney/5/97.[NS1] (Mus musculus) PubMed
7057.
The authors showed, in vitro, a direct interaction between Orf virus anaphase promoting complex regulator and APC2 and its interference with interactions between APC11 and APC2.[anaphase promoting complex regulator] (Mus musculus) PubMed
7058.
the potential KLV-HAR1 receptor complex regulates symbiotic nodule development and that KLV is also a key component in other signal transduction pathways that mediate non-symbiotic shoot development [klavier] (Mus musculus) PubMed
7059.
These findings not only provide a structural basis for the catalytic machinery of CUS but also suggest further strategies toward expanding the biosynthetic repertoire of the type III polyketide synthase enzymes.[Curcuminoid synthase] (Mus musculus) PubMed
7060.
This study demonstrates that the PfEMP1 semi-conserved head structure is under selection for protein transport, in addition to its known roles in adhesion.[PfEMP1] (Mus musculus) PubMed
7061.
break-induced Rad3 and Ddb1-Cul4(Cdt)(2) ubiquitin ligase-dependent Spd1 degradation and RNR activation promotes postsynaptic ssDNA gap filling during HR repair [Rad3, Ddb1, Cul4(Cdt)(2); no strain listed] (Mus musculus) PubMed
7062.
[PbHad32p] - plays an important role in adherence to host cells and influences pathogenicity (Mus musculus) PubMed
7063.
a negative feedback mechanism by which intracellular cAMP synthesis is inhibited by PKA through Cdc25p phosphorylation [Cdc25p] (Mus musculus) PubMed
7064.
Orexin A was found in the beta cells of cattle, sheep, and swine where it may be implicated in the control of pancreatic activity.[orexin A] (Mus musculus) PubMed
7065.
Overexpression of mir-57 causes dramatic posterior defects, which also mimic the phenotypes of mutant alleles of a posterior Hox gene, nob-1.[mir-57, Nob-1] (Mus musculus) PubMed
7066.
The study describes the structure of Escherichia coli rhomboid GlpG covalently bound to a mechanism-based isocoumarin inhibitor. [GlpG] (Mus musculus) PubMed
7067.
LytM deletion mutant lysed at a significantly faster rate compared with the wild-type. [LytM] (Mus musculus) PubMed
7068.
We report that through binding with the human nuclear receptor importin alpha5 (Impalpha5), the viral NP is no longer oligomeric but maintained as a monomer inside the complex. (Mus musculus) PubMed
7069.
These results suggest FliO maintains FliP stability through transmembrane domain interaction.[FliO, FliP] (Mus musculus) PubMed
7070.
These results reveal a novel mechanism for the control of the abscisic acid/gibberellic acid balance in rice which is regulated by OsAP2-39 that in turn regulates plant growth and seed production.[OsAP2-39] (Mus musculus) PubMed
7071.
Als5p nanodomains result from protein redistribution triggered by force-induced conformational changes in the initially probed proteins, rather than from nonspecific cell-wall perturbations.[Als5p] (Mus musculus) PubMed
7072.
BKIP-1 is a novel auxiliary subunit critical to SLO-1 function in vivo. (Mus musculus) PubMed
7073.
Yeast seipin is in a large discrete protein complex and plays at least a structural role in organizing droplets or in communication between droplets and ER Seipin protein, strain BY4742] (Mus musculus) PubMed
7074.
influence of ATPgammaS on the competitive binding of RecA and single-stranded binding protein (SSB) on single-stranded DNA [RecA] (Mus musculus) PubMed
7075.
dcaf26 was required for all of the DNA methylation.[DCAF26] (Mus musculus) PubMed
7076.
MoCel6A showed higher hydrolytic activities on phosphoric acid-swollen cellulose (PSC), beta-glucan, and cellooligosaccharide derivatives than on cellulose, of which the best substrates were cellooligosaccharides.[MoCel6A] (Mus musculus) PubMed
7077.
The extended signal peptide region is not essential for the secretion or the function of Pet. [Pet] (Mus musculus) PubMed
7078.
Rice Starch Regulator1 is an AP2/EREBP family transcription factor that negatively regulates starch biosynthesis and is important for starch content and structure. [RSR1] (Mus musculus) PubMed
Overexpression of the ERF1-1 B-3 ethylene response factor quantitatively increases resistance to Rhizoctonia and Phytophthora but not root knot nematode. (Mus musculus) PubMed
7081.
Those who reported midlife physical activity, but were APOE 4 carriers, did not have reduced risk for dementia. (APOE 4] (Mus musculus) PubMed
7082.
Single-stranded DNA binding protein is targeted to the apicoplast and it binds to apicoplast DNA (Single-stranded DNA binding protein). (Mus musculus) PubMed
7083.
Heterodimer formation of RcsB and BglJ expands the role of the Rcs two-component system and the network of regulators affecting the bgl promoter via H-NS repression.[BglJ; RcsB; H-NS] (Mus musculus) PubMed
7084.
Aah and AIDA-I are transcribed in a growth-dependent fashion, mainly at the start of the stationary phase. [AIDA-I] (Mus musculus) PubMed
7085.
Snl6 is required for NH1-mediated resistance to Xanthomonas oryzae pv. oryzae.[Snl6, NH1] (Mus musculus) PubMed
7086.
the involvement of quelling defective-2 interacting protein (qip(+)), a Neurospora gene whose function is essential to silencing by quelling, in meiotic silencing, and normal sexual development [QIP] (Mus musculus) PubMed
7087.
Presented is the cryo-electron microscopy structures of tmRNA-SmpB accommodated or translocated into stalled ribosomes.[SmpB] (Mus musculus) PubMed
7088.
Translesion synthesis efficiency of Pol eta depends critically on the size of the bulky adduct forming the lesion.[DNA polymerase eta] (Mus musculus) PubMed
7089.
The ability of p8 to simultaneously anergize and cluster T cells, together with its induction of cellular conduits, secures virus propagation while avoiding the host's immune surveillance.[p8] (Mus musculus) PubMed
7090.
We conclude that VP4 protein appears as a product of RNA encapsidation, and that defective processing of capsid proteins precludes genome encapsidation. [VP4] (Mus musculus) PubMed
7091.
These results indicate that the competitive advantage of the rpoS(Ty19) mutant is dependent on Crl and suggest that crl plays a role in the appearance of rpoS mutants in bacterial populations.[crl; rpoS] (Mus musculus) PubMed
7092.
QDE-2-interacting protein is important for the production of single-stranded siRNA during Quelling [QIP] (Mus musculus) PubMed
7093.
SUB1 is the first putative serine protease experimentally described for T. vaginalis. [Sub1] (Mus musculus) PubMed
7094.
The authors demonstrating that Escherichia coli laminin-binding fimbriae , encoded by ycbQRST, contributes to adherence to human intestinal epithelial cells and to cow and pig gut tissue in vitro.[ycbS & T] (Mus musculus) PubMed
7095.
study describes how Gwl activation results in PP2A inhibition; identified Arpp19 and alpha-Endosulfine that, when phosphorylated by Gwl, associate with and inhibit PP2A promoting mitotic entry [Greatwall, Gwl) (Mus musculus) PubMed
7096.
the position of the triphosphate group (5' and not 3') on the ribose/deoxyribose ring is important for recognition by ANT(4'); NTPs with larger substituents at the 3'-position of the ribose ring are not cosubstrates for ANT(4'). [ANT9(4')] (Mus musculus) PubMed
7097.
conformational transitions in an oligomeric and high molecular weight class II alpha-mannosidase from Aspergillus fischeri [class II alpha-mannosidase] (Mus musculus) PubMed
7098.
dst1 encodes a homolog of WC-1, a fungal blue-light photoreceptor first identified in Neurospora crassa, while dst2 encodes a novel protein with a putative flavin adenine dinucleotide (FAD)-binding-4 domain.[dst1 & dst2] (Mus musculus) PubMed
7099.
Two putative mosquito glutamate decarboxylase-like enzymes of mosquitoes were expressed and their substrate specificity and biochemical properties, were analyzed. [GDC] (Mus musculus) PubMed
7100.
Two putative mosquito glutamate decarboxylase-like enzymes of mosquitoes were expressed and their substrate specificity and biochemical properties, were analyzed.[ADC] (Mus musculus) PubMed
7101.
a large-scale comprehensive study to determine the genotype of Helicobacter pylori cagA gene in Hong Kong (Mus musculus) PubMed
7102.
Results identified a Leishmania major-specific gene that can partly compensate for the loss of virulence observed for L. major HSP100 null mutants [Hsp100]. (Mus musculus) PubMed
7103.
The GRAS Domain of SLR1 Stabilizes the Interaction between GID1 and SLR1. [GID1; SLR1] (Mus musculus) PubMed
7104.
Grapevine rupestris stem pitting-associated virus capsid protein contains a nuclear localization signal "KRKR" near its N-terminus, which is conserved among all five strains whose genomes are completely sequenced.[capsid protein] (Mus musculus) PubMed
7105.
Extracellular pH controls the ZmSUT1 and UmSRT1 at the host/pathogen interface. [SRT1] (Mus musculus) PubMed
7106.
There were a total of 14 single nucleotide polymorphisms (SNPs) in KRTAP1-4 identified and these SNPs tended to be clustered in two regions.[KRTAP1-4] (Mus musculus) PubMed
7107.
Purine starvation induces upregulation of the purine permease NT1 in wild-type parasites. [NT1] (Mus musculus) PubMed
7108.
MC159 is a dual-function immune modulator that regulates host cell death as well as NF-kappaB responses by innate immune signaling receptors. (MC159) (Mus musculus) PubMed
7109.
Mutations in both EspP1-25 and L22 suppress the aggregation of a cytoplasmic protein containing EspP1-25. [EspP] (Mus musculus) PubMed
7110.
The crystallographic structures of Encephalitozoon cuniculi Iws1 and the Iws1/N-terminal region of Spt6 complex reveal two conserved binding subdomains in Iws1. [Iws1, Spt6] (Mus musculus) PubMed
7111.
mutational analysis and crystallography of aminoacylhistidine dipeptidase from Vibrio alginolyticus reveal a new architecture of M20 metallopeptidases [PepD] (Mus musculus) PubMed
7112.
Analysis of the expression pattern of wheat TaPDS and TaZDS in different tissues revealed that the transcripts levels were higher in leaves and flowers petals, followed by in inflorescences, and were nearly absent in the roots and seeds.[PDS] (Mus musculus) PubMed
7113.
sigma factor SigV plays a key role in the original model of lysozyme resistance and virulence of Enterococcus faecalis [SigV] (Mus musculus) PubMed
7114.
Adc1 is expressed in leaf, root & stem. Adc2 encodes a 629-AA protein, predicted M.W. 67 kDa. The Adc2 gene has an intron & a short upstream open reading frame in the 5'-UTR. Its expression is restricted to stem tissue. ADC1. ADC2. (Mus musculus) PubMed
7115.
In C. elegans, Zfr mRNA expression was barely detectable in the fertilized egg and the L1 stage, but increased in the adult organism (Mus musculus) PubMed
7116.
CagA exploits a polarity-signaling pathway to induce oncogenesis [CagA] (Mus musculus) PubMed
7117.
crystal structure of RibU, the S component of the ECF-type riboflavin transporter from Staphylococcus aureus at 3.6-A resolution [ribU] (Mus musculus) PubMed
7118.
Rmi1 serves to stimulate DNA decatenation, removing the last linkages between the repaired and template DNA molecules. (Mus musculus) PubMed
7119.
RFC(Ctf18) is essential for the Mrc1-dependent activation of Rad53 and for the maintenance of paused replication forks. [Ctf18] (Mus musculus) PubMed
7120.
Pif1 and Exo1 are required for different nuclease activities that generate ssDNA and activate the DNA damage checkpoint following Cdc13 inactivation.[Pif1, Exo1] (Mus musculus) PubMed
7121.
The authors show that RCO-1 and RCM-1 participate in the light-transduction pathway of Neurospora and has a role in photoadaptation by repressing gene transcription after long exposures to light.[RCM-1] (Mus musculus) PubMed
7122.
These data suggest that POR1 encodes a transcriptional activator widely regulating fatty acid metabolism in Y. lipolytica. [POR1] (Mus musculus) PubMed
7123.
NusG slows down rather than facilitates transcript elongation by its cognate RNA polymerase (NusG). (Mus musculus) PubMed
7124.
The crystal structure reveals that the P2 C protein forms a symmetric dimer oriented to bind the major groove of two consecutive turns of the DNA (C protein). (Mus musculus) PubMed
7125.
A comparison of the structure of NpmA with KamB from the Streptoalloteichus tenebrarius provides insights into the likely molecular mechanisms of action of the A1408 methyltransferases (NpmA). (Mus musculus) PubMed
7126.
Mutations of conserved, polar residues within the K-channel block or inhibit steady state aa3 oxidase activity. (aa3-type cytochrome c oxidase) (Mus musculus) PubMed
7127.
PIFTC3, an orthologue of nematode DYF-13, participates in a macromolecular complex with components of both IFT-A and IFT-B. [PIFTC3] (Mus musculus) PubMed
7128.
The expression pattern of the MtF3H gene was analyzed.[F3H] (Mus musculus) PubMed
7129.
p13 might control key processes regulated through Ca2+ signaling such as activation and death of T cells, the major targets of HTLV-1 infection. (p13) (Mus musculus) PubMed
7130.
These results indicate that PriA is involved in the discontinuous synthesis of nascent DNA.[PriA] (Mus musculus) PubMed
7131.
A novel Ras small monomeric GTPase Rsr1 gene, designated PmRsr1, from yeast-form Penicillium marneffei, was isolated and characterized.[PmRsr1] (Mus musculus) PubMed
7132.
Substrate specificity of Os3BGlu7 and HvBII depends on the inherent conformational and spatial flexibilities of gluco- and manno-configured substrates in the enzymes' active sites [Os3BGlu7] (Mus musculus) PubMed
7133.
The ABC efflux system PatA/PatB is induced upon exposure to subinhibitory concentrations of fluoroquinolones, whether substrates of the transporter or not.[PatA & PatB] (Mus musculus) PubMed
7134.
The eukaryotic gamma subunit of eukaryotic translation initiation factor 2 is able to bind by itself the initiator tRNA. The two peripheral alpha and beta subunits are required for strong binding. [eukaryotic translation initiation factor 2] (Mus musculus) PubMed
7135.
The results of a 200-ns molecular dynamics simulation of the sodium-dependent galactose cotransporter vSGLT, are reported.[vSGLT] (Mus musculus) PubMed
7136.
The observed dynamics shows that Phosphoglycerate kinase has the flexibility to allow fluctuations and displacements that seem to enable the function of the protein.[PGK] (Mus musculus) PubMed
7137.
The interaction of human adenovirus E4orf4 with both Cdc55 and B55 involves residues within blades 1 and 2, a finding that is consistent with the idea that E4orf4 binding may block the dephosphorylation of at least some PP2A substrates. [cdc55] (Mus musculus) PubMed
7138.
These results indicated that the hydrophobic domain of infectious bronchitis virus E protein alters the host secretory pathway to the apparent advantage of the virus. (Mus musculus) PubMed
7139.
NSP1 suppresses protein sythesis in mammalian cells and Hela cells extracts but not rabbit reticulocytes. [NSP1] (Mus musculus) PubMed
7140.
Infection of chickens with R65(mono)-S-ETR or R65(mono)-S-ER clevage site in haemagglutinin led to slight transient respiratory symptoms, whereas R65-infected animals died within 2 days.[haemagglutinin] (Mus musculus) PubMed
7141.
The authors demonstrate that NS1 of the highly pathogenic avian influenza A/Duck/Hubei/L-1/2004 (H5N1) virus interacts with human Ubc9 and SUMO1 is conjugated to H5N1 NS1 in both transfected and infected cells.[NS1] (Mus musculus) PubMed
7142.
RCMV miRNA miR-r111.1-2 is highly expressed in the salivary glands and miR-R87-1 is expressed in most tissues during the acute infection phase in vitro and in vivo and associated with a stage of viral infection.[miR-r111.1-2, miR-R87] (Mus musculus) PubMed
7143.
Translocation and unwinding by single DnaB molecules in three tethered DNA geometries held under tension, was investigated.[DnaB] (Mus musculus) PubMed
7144.
The results suggest a two-step opening mechanism that gives rise first to a semi-open conformation upon adsorption of the lipase at the water/organic solvent interface, followed by a further opening of the lid upon substrate binding.[Lipase] (Mus musculus) PubMed
7145.
The small hydrophobic (SH) protein of JPV plays a role in inhibiting TNF-alpha expression. [SH protein] (Mus musculus) PubMed
7146.
These data indicate that Atf1p plays a direct and specific role in targeting integration in the promoter of fbp1. [Atfp1, fbp1] (Mus musculus) PubMed
7147.
The interaction of human adenovirus E4orf4 with both Cdc55 and B55 involves residues within blades 1 and 2, a finding that is consistent with the idea that E4orf4 binding may block the dephosphorylation of at least some PP2A substrates. [E4ORF4] (Mus musculus) PubMed
7148.
A detailed computational model of CaMKII and PKA signaling in cardiac myocytes that provides unique insights into their regulation of normal and pathological Ca(2+) handling, was developed.[CaMKII] (Mus musculus) PubMed
7149.
Sororin and Eco2 work together to form a unique regulatory module that limits cohesion to cells with replicated chromatin and support a model in which cohesion in vertebrates is not fully established until the G2 phase of the cell cycle. [Eco2] (Mus musculus) PubMed
7150.
2 genes: Low Rif2 content marks short telomeres for preferential elongation. [Rif2] The absence of Mec1 at short telomeres target them for preferential elongation. [Mec1] (Mus musculus) PubMed
7151.
Neurovirulence of interferon-resistant rabies virus correlates with the capacity of the virus phosphoprotein to prevent activation of IRF3 and IRF7. (Mus musculus) PubMed
7152.
These data suggest that PB1-F2 N66S may contribute to the delay of innate immune responses, allowing for unchecked viral growth and ultimately severe immunopathology observed in the lungs.[PB1-F2] (Mus musculus) PubMed
7153.
This work shows a second binding site for divalent metal cations in phosphofructokinase-2 and by means of substitution studies establishes that, besides Mg2+, Mn2+ can interact at this site and with a higher affinity than Mg2+. [phosphofructokinase-2] (Mus musculus) PubMed
7154.
Identify semaphorin 3G (Sema3G) as a primarily endothelial cell-expressed class 3 semaphorin that controls endothelial and smooth muscle cell functions in autocrine and paracrine manners. (Mus musculus) PubMed
7155.
Bacteriophage Sf6 virion contains two proteins, OmpA and OmpC, from its host Shigella flexneri.[OmpA and OmpC] (Mus musculus) PubMed
7156.
The structure of Hbs1 with and without GDP and a low-resolution model of the Dom34-Hbs1 complex is presented. [Hbs1] (Mus musculus) PubMed
7157.
A Bo10 deletion virus was viable but showed a growth deficit associated with reduced binding to epithelial cells.[Bo10] (Mus musculus) PubMed
7158.
The Walleye dermal sarcoma virus cyclin functions as a structural ortholog of cyclin C in spite of its limited amino acid sequence identity with C cyclins or with any known cyclins and activates Cdk8 and Cdk3.[cyclin] (Mus musculus) PubMed
7159.
The authors report that a protein encoded in the 34-kbp genome of the rudivirus SIRV1 is a member of the replication initiator (Rep) superfamily of proteins, which initiate rolling-circle replication (RCR) of diverse viruses and plasmids. (Mus musculus) PubMed
7160.
In the present study, it was shown that ShvR negatively regulates its own expression, as is typical for LysR-type regulators.[ShvR] (Mus musculus) PubMed
7161.
This study combined different approaches to investigate the role and mechanism of sigma(E)-dependent activation in X. campestris pv. campestris. (Mus musculus) PubMed
7162.
The V-ATPase accessory subunit Ac45 represents the first regulator of the proton pump and controls V-ATPase-mediated granular acidification that is necessary for efficient prohormone processing.[Ac45] (Mus musculus) PubMed
7163.
The entire extra-cellular region of PrkC (residues 378-664), containing three predicted PASTA domains and an extra-domain of unknown function, has been successfully crystallized using vapor-diffusion methods[PrkC] (Mus musculus) PubMed
7164.
Vps4 functions as a stable oligomer that acts upon individual Endosomal Sorting Complexes Required for Transport [ESCRT-III] subunits to facilitate ESCRT-III disassembly.[Vps4] (Mus musculus) PubMed
7165.
The Cdk1 kinase and two Cdk phosphorylation sites in the nucleoporin Nup1 were required for peripheral targeting of INO1 and GAL1.[Cdk1, Nup1, INO1, GAL1] (Mus musculus) PubMed
7166.
RNase MRP was involved in viral (Tomato Bushy stunt virus) RNA degradation and RNA recombination in a Saccharomyces cerevisiae model host.[Rnase MRP] (Mus musculus) PubMed
7167.
The data presented in this study demonstrate that PB2-E158G is a novel pathogenic determinant of pandemic influenza A viruses H1N1 and H5 in the mouse model. [PB2] (Mus musculus) PubMed
7168.
miR-M3 blocked cisplatin-induced apoptosis by directly downregulating Smad2 protein expression.[miR-M3] (Mus musculus) PubMed
7169.
These results support the proposal that SoxR senses redox-active molecules, such as actinorhodin in S. coelicolor, and induces a protective function against them.[SoxR] (Mus musculus) PubMed
7170.
The genetic analysis reported here also reveals that the slow growth and other defects associated with inactivation of rluD in E. coli K-12 strains are due to a defective RF2 protein, with a threonine at position 246, which is present in all K-12 strains. (Mus musculus) PubMed
7171.
OsOxi1 positively regulates defense responses through the phosphorylation of OsPti1a. [OsOxi1; OsPti1a] (Mus musculus) PubMed
7172.
report describes a lack of association between H. pylori CagA-protein polymorphisms and pathogenesis [CagA] (Mus musculus) PubMed
7173.
The study provides molecular details of how yeast frataxin (Yfh1) interacts with Isu1 as a structural module to improve our understanding of the multiprotein complex assembly that completes Fe-S cluster assembly. [Yfh1, Isu1] (Mus musculus) PubMed
7174.
Isolated ExbB adopts a stable homooligomer with four to six monomers.[ExbB] (Mus musculus) PubMed
7175.
Reported are several high-resolution crystal structures of the nicotinamidase from Streptococcus pneumoniae (SpNic) in unliganded and ligand-bound forms. [SpNic] (Mus musculus) PubMed
7176.
These data show that PfHslV is located to the plasmodial mitochondrion and presumably has vital function within this organelle which makes it an attractive target for interventions.[PfHslV] (Mus musculus) PubMed
7177.
in pandemic 2009 H1N1 isolates, the H1N1v NS1 gene was more conserved than previous epidemic strains; a closer genetic identity of H1N1v with the swine than the human reference strains was shown; hot-spots were shown in the H1N1v NS1 aa sequence [NS1] (Mus musculus) PubMed
7178.
These results indicate that CRP functions as an essential activator, whereas SmcR functions in the presence of CRP for full vvpE expression.[CRP, SmcR & vvpE] (Mus musculus) PubMed
7179.
We show that White Collar Complex directly controls the expression of 24 transcription factor genes, including the clock-controlled adv-1 gene, which controls a circadian output pathway required for daily rhythms in development. [adv-1] (Mus musculus) PubMed
7180.
The silencing of MTL3 locus requires the yKu70, yKu80, and Rif1 proteins. [yKU70, Yku80, Rif1] (Mus musculus) PubMed
7181.
A novel GlcNAc-induced gene, GIG1, which is not essential for GlcNAc catabolism or the induction of hyphae, was identified and is required for fro sensitivity to nikkomycin z.[GIG1] (Mus musculus) PubMed
7182.
Three PABP (poly(a) binding protein) homolouges are simultaneousy expressed but differ in protein and RNA binding properties and in subcellular localization under conditions of transcription inhibition. [PABP1, PABP2, PABP3]. (Mus musculus) PubMed
7183.
Both cholesterol and the putative bile salt efflux pump HefC play important roles in H. pylori resistance to bile salts and ceragenins.[HefC] (Mus musculus) PubMed
7184.
This study demonstrated that disruption of the fadD gene has marked effects on expression of the ToxR virulence regulon, especially TcpP, motility, and in vivo lethality of V. cholerae.[TcpP] (Mus musculus) PubMed
7185.
structure of c-Rph1 is composed of a JmjN (Jumonji N) domain, a long beta-hairpin, a mixed structural motif and a JmjC domain[Rph1] (Mus musculus) PubMed
7186.
crystal structure of Lassa virus NP at 1.80 A resolution, which reveals amino (N)- and carboxy (C)-terminal domains with structures unlike any of the reported viral NPs [NP] (Mus musculus) PubMed
7187.
The the DNA double-strand breaks (DSB) resection and procrossover functions of Exo1 during meiosis involve temporally and biochemically distinct activities. (EXO1 protein, S cerevisiae) (Mus musculus) PubMed
7188.
Gene disruption of bcass1 was carried out and generated a strict auxotroph, unable to grow without exogenous arginine supplementation.[Bcass1] (Mus musculus) PubMed
7189.
Taken together, these observations support the conclusion that ChxR, in the absence of phosphorylation, exhibits many of the characteristics of a phosphorylated (active) OmpR/PhoB subfamily response regulator.[ChxR] (Mus musculus) PubMed
7190.
Covalently modified by oligo-(R)-3-hydroxybutyrates (cOHB) conjugated residues in the ion pathway, S102 and S129 were mutated to determine the influence of cOHB on channel properties.[KcsA] (Mus musculus) PubMed
7191.
Methionine sulfoxide reductases MsrA and MsrB are involved in the regulation of mitochondrial function. [MsrA,MsrB] (Mus musculus) PubMed
7192.
[gag p24] Cytotoxic T cell escape at arginine264 in a conserved epitope of HIV gag p24 is a major determinant of subsequent viral load in HLA-B*27-positive individuals with HIV infection. (Mus musculus) PubMed
7193.
OsSIZ1 and OsSIZ2 are localized to the nucleus and function as SUMO E3-ligases. [Siz2] (Mus musculus) PubMed
7194.
VX-4 might function as a hemoglobinase in the acidic parasite food vacuole, a maturase of Plasmodium vivax plasmepsin 4 at neutral or acidic pH, and a cytoskeleton-degrading protease in the neutral erythrocyte cytosol.[VX-4] (Mus musculus) PubMed
7195.
Prm1, a pheromone-regulated membrane glycoprotein, functions on the plasma membrane at sites of cell-cell contact and enhances fusion during mating. [Prm1] (Mus musculus) PubMed
7196.
The transcriptional activator Met4 functions as a substrate-specificity factor in the context of SCF(Met30/Met4) to coordinate cofactor degradation with its own activity status. (MET4 protein, S cerevisiae) (Mus musculus) PubMed
7197.
A network of cell wall proteins comprising Als3p, Hwp1p, and Eap1p, with complementary adhesive functions, promotes interactions of C. albicans with host and bacterial molecules, and effective colonization within polymicrobial communities. [Hwp1p, Eap1p] (Mus musculus) PubMed
7198.
The brassinosteroid (BR)-induced initial H(2)O(2) production activates ZmMPK5, which is involved in self-propagation of apoplastic H(2)O(2) via regulation of NADPH oxidase gene expression in BR-induced antioxidant defence systems.[NADPH oxidase] (Mus musculus) PubMed
7199.
inactivation of katA (catalase) and sodA (Superoxide dismutase) hypersensitive to seawater stress at 4 degrees C (Mus musculus) PubMed
7200.
Here we show that the vesicle-associated protein Sec4 localizes to a subapical spot, confirming that secretory vesicles accumulate in the putative C. albicans Spitzenkorper. [Sec4] (Mus musculus) PubMed
7201.
PilA and SurG are necessary for conidial eisosome organization in ways that differ from those for their S. cerevisiae homologues. [PilA, SurG] (Mus musculus) PubMed
7202.
Slab is required for endocytosis and polarity maintenance in hyphae. [SLaB] (Mus musculus) PubMed
7203.
Tthe N terminus of phophosidesterases PDEB1 and PDEB2 is essential for determining the flagellar skeleton location of PDEB1, and the cell body location of PDEB2. [PDEB1, PDEB2] (Mus musculus) PubMed
7204.
SsgB promotes the polymerization of FtsZ. [ssgB and FtsZ] (Mus musculus) PubMed
7205.
crystal structure of Dhaf4260 from Desulfitobacterium hafniense DCB-2 was determined by single-wavelength anomalous diffraction (SAD) to a resolution of 2.01 A[Dhaf4260 ] (Mus musculus) PubMed
7206.
New interactions of PthAs with citrus proteins involved in protein folding and K63-linked ubiquitination, are described.[PthA] (Mus musculus) PubMed
7207.
While Pif1 is a monomer in solution, the study shows that binding of ssDNA to Pif1 induces protein dimerization. [Pif1] (Mus musculus) PubMed
7208.
These findings are consistent with the idea that RNA silencing is an antiviral defence mechanism and that the counter-defence role of P25 is through the degradation of AGO proteins via the proteasome pathway.[P25] (Mus musculus) PubMed
7209.
Described is the 2.0 A resolution crystal structure of RB69 DNA polymerase.[DNA polymerase] (Mus musculus) PubMed
7210.
crystals of Swi5 and Swi5-DeltaN180Sfr1 are likely to contain one tetramer and two heterodimers in the asymmetric unit, respectively[Swi5 and Sfr1] (Mus musculus) PubMed
7211.
crystal of formate oxidase was orthorhombic and belonged to space group C222(1)[ formate oxidase] (Mus musculus) PubMed
7212.
In this study, Quantum Mechanics/Molecular Mechanics rare event trajectories from the transition state structures of the rate limiting step of the thymidylate synthase catalyzed reaction have been carried out. [thymidylate synthase] (Mus musculus) PubMed
7213.
results demonstrate that the ClC subunit alone is the basic functional unit for transport and that cross-subunit interaction is not required for Cl(-)/H(+) exchange in ClC transporters [ClC-ec1] (Mus musculus) PubMed
7214.
ROA plays multiple roles in maintaining the proper morphology and discharge of ascospores in G. zeae[ROA] (Mus musculus) PubMed
7215.
These results suggest that the translation initiation efficiency of the antiterminator proteins, at least in part, determines whether the target genes are subject to glucose repression.[BglG & BglG2] (Mus musculus) PubMed
7216.
The structure of the complement-binding domain of Staphylococcus aureus protein Sbi (Sbi-IV) in complex with ligand C3d is presented.[Sbi] (Mus musculus) PubMed
7217.
only the GTPase domains are required for the mitochondrial inheritance function of Gem1p [Gem1p] (Mus musculus) PubMed
7218.
Substance P and SP-R mRNA expressions were reduced after IMETIT treatment of allergic rhinitis. (Mus musculus) PubMed
7219.
expression of rv-cyclin protects the fish liver from carcinogen damage and delays onset of malignancy (Mus musculus) PubMed
7220.
newly synthesized Cox1 physically interacts with a complex of proteins involving Ssc1, Mss51, and Cox14 [Cox25][Mss51][Ssc1][Cox14][Cox1] (Mus musculus) PubMed
7221.
These results suggested that Rice ragged stunt virus Pns6 functions as a virus suppressor of RNA silencing that targets an upstream step of the dsRNA formation in the RNA silencing pathway.[Pns6] (Mus musculus) PubMed
7222.
biochemical and structural characterization of an effector protein (NleL) from Escherichia coli O157:H7, a widespread pathogen causing severe foodborne diseases [NleL] (Mus musculus) PubMed
7223.
TcMAPK2 has an important role in the stress response of Trypanosoma cruzi and may be important in regulating proliferation and differentiation (MAPK2). (Mus musculus) PubMed
7224.
The crystal structure of Leishmania major ADP-ribosylation factor-like 1 (ARL1) in complex with GDP has been determined to 2.1 A resolution and reveals a high degree of structural conservation with human ADP-ribosylation factor 1 (ARF1). [Arf1] (Mus musculus) PubMed
7225.
hepatitis C virus infection can induce endoplasmic reticulum stress, with NS2 protein being a major mediator.(NS2 PROTEIN) (Mus musculus) PubMed
7226.
Together, these results demonstrated that the induction of CXCL8 in human neutrophils activated by Streptococcus pneumoniae PspA and PspC was regulated by p38 MAPK and NF-kappaB pathways.[PspA & PspC] (Mus musculus) PubMed
7227.
prevalence of different ga2 alleles within teosinte and maize was evaluated, and the implications of this distribution on a role for the Ga2 system in the reproductive isolation of Zea subspecies are discussed[ga2] (Mus musculus) PubMed
7228.
analysis ofAP-1 mu1A and mu1B expression revealed tissue-specific expression for either one during embryogenesis and in adult tissues in contrast to their expression in mammalia [AP-1 mu1A and mu1B (Mus musculus) PubMed
7229.
The double null lys21Delta/lys22Delta mutant lacked homocitrate synthase activity and exhibited lysine auxotrophy in minimal media that could be fully rescued by the addition of 0.5-0.6 mM L-lysine.[lys22] (Mus musculus) PubMed
7230.
Specific expression in the growing part of rice leaves is well in agreement with the role of SUB1A in suppressing leaf elongation under submergence.[SUB1A] (Mus musculus) PubMed
7231.
The amino acid substitutions in conserved sequences of penicillin-binding proteins 2B, 1A and 2X increase MIC for beta-lactam antibiotics. (Mus musculus) PubMed
7232.
analysis of positional importance of aromatic residues and lysine in the interactions of peptides with the Plasmodium falciparum Hsp70-1 (Mus musculus) PubMed
7233.
A single dominant gene, Ml3D232, confers resistance in the host seedling stage.[M13D232] (Mus musculus) PubMed
7234.
Presented is the structure of the class II ribonucleotide reductase tmNrdJ from Thermotoga maritima in three complexes: (i) with allosteric effector deoxythymidine triphosphate, substrate GDP, and adenosylcobalamin. [tmNrdJ] (Mus musculus) PubMed
7235.
Trypanosoma brucei Tob55 is essential for cell survival and is required for VDAC assembly on outer mitochondrial membrane. [Tob55] (Mus musculus) PubMed
7236.
the histidine coordination and stability of the [2Fe-2S] cluster in the Fra2-Grx3 complex are essential for iron regulation in yeast [Fra2][Grx3] (Mus musculus) PubMed
7237.
Results suggest that bradykinin is involved in parainfluenza-3 virus-induced inflammatory cell influx and airway hyperreactivity.(bradykinin, i.e., kininogen 1/kng1 gene) (Mus musculus) PubMed
7238.
ArcA, acting independently of acetate metabolism, is also required for maximum lifespan extension in the lipA and lpdA mutants, indicating that these mutations promote entry into a mode normally associated with a low-oxygen environment [ArcA] (Mus musculus) PubMed
7239.
The putative WRKY transcription factor OsWRKY80 is up-regulated in rice leaves, stems and roots after Fe-excess treatment.[OsWRKY80] (Mus musculus) PubMed
7240.
Changes in biomass yield, food characteristics, and genetic stability of S. cerevisiae strains overexpressing HAP4 are reported.[HAP4] (Mus musculus) PubMed
7241.
two chitin-binding proteins (BmPM-P43 and BmPM-P41) from the peritrophic membrane of the silkworm, Bombyx mori, were identified and cloned (Mus musculus) PubMed
7242.
FATP1 gene polymorphisms were associated with chicken carcass traits or was linked with the major gene.[FATP1] (Mus musculus) PubMed
7243.
XA13, COPT1, and COPT5 are associated with Cu redistribution in rice. Activating Xa13 makes plants susceptible to bacterial blight disease. (Mus musculus) PubMed
7244.
Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans. [GSR-1 glutathione reductase] (Mus musculus) PubMed
7245.
study of the sodium/galactose transporter from Vibrio parahaemolyticus (vSGLT), consisting of molecular dynamics simulations, biochemical characterization and a new crystal structure of the inward-open conformation at a resolution of 2.7 A [vSGLT] (Mus musculus) PubMed
7246.
RelA is cleaved by chlamydial protease-like activity factor (CPAF), which impairs proinflammatory signaling in cells infected with Chlamydiae; IL-1beta-dependent secretion of IL-8 is also reduced by CPAF expression [CPAF] (Mus musculus) PubMed
7247.
These findings suggest that trimethylation of pilA1 at the C-terminal lysine may be essential for the biogenesis of functional pili.[pilA1] (Mus musculus) PubMed
7248.
sbrA and sbrB were found to contain open reading frames encoding small, highly basic peptides that are conserved among Staphylococci, SbrC did not contain any likely open reading frame and thus constitute a genuine non-coding sRNA [SbrA, SbrB,SbrC] (Mus musculus) PubMed
7249.
Adhesion is mediated through Scl1 on bacterial surface and protein receptor(s) on epithelial cells. [Scl1] (Mus musculus) PubMed
7250.
The direct and functional interaction of SCO3201 with the promoter region of scbA, a gene under the positive control of the TetR-like regulator, ScbR, was indeed demonstrated by in vitro as well as in vivo approaches.[SCO3201] (Mus musculus) PubMed
7251.
Pseudouridylation of RNA can be induced at sites of imperfect sequences, and Pus7p and snR81 RNP can catalyse both constitutive and inducible pseudouridylation [SnR81 RNP, Pus7p] (Mus musculus) PubMed
7252.
The repair defect caused by the triple deletion of Pph3, Ptc2, and Ptc3 is most prominent when a DSB is slowly repaired and the DNA damage checkpoint is fully activated.[Pph3, Ptc2, Ptc3] (Mus musculus) PubMed
7253.
Eleven human host proteins interacting with Core and 45 interacting with NS4B were identified.[NS4B, Core protein] (Mus musculus) PubMed
7254.
Enzymatic activity of virulence factors ecreted aspartyl proteinase and phospholipase were found to be significantly high in amphotericin-B resistance strains. [aspartyl proteinase, phospholipase] (Mus musculus) PubMed
7255.
genes encoding TcCox10 and TcCox15 are responsible for coding heme O and heme A synthases and are differentially transcribed during the parasite life cycle [TcCox10] [TcCox15] (Mus musculus) PubMed
7256.
Vba2p is involved in basic amino acid transport in S. pombe under diverse conditions [Vba2p] (Mus musculus) PubMed
7257.
[IL-21; interleukin-21] Multiple signaling pathways involved in IL-21-induced expression of interferon-gamma, interleukin (IL)-10, and IL-22 have been found to be involved in recombinant rainbow trout IL-21 signaling. (Mus musculus) PubMed
7258.
demonstrating that GRA15 alone is sufficient for NF-kappaB activation[GRA15] (Mus musculus) PubMed
7259.
Data show that loss-of-function mutations of moc-3 and dph-3 effectively suppress the Multivulva (Muv) phenotype of the lin-1(e1275, R175Opal) mutation: [MOC-3 & DPH-3] (Mus musculus) PubMed
7260.
Data suggest that mus-10 is involved in mitochondrial maintenance: [MUS-10] (Mus musculus) PubMed
7261.
Study provides insights into the comprehensive signaling networks orchestrated by carbonic anhydrase Can2/CO2-sensing pathways in Cryptococcus neoformans strain H99: [Can2] (Mus musculus) PubMed
7262.
These results suggest a suppressive effect of HBZ on Maf function, which may have a significant role in HTLV-1 related pathogenesis [HBZ]. (Mus musculus) PubMed
7263.
The importance of Hsc70 in AtlE adhesin-mediated internalization was demonstrated by the inhibition of Staphylococcus aureus internalization with anti-Hsc70 antibodies.[AtlE] (Mus musculus) PubMed
7264.
The reduction of virulence in the trag mutant compared to the wild-type in animal model systems, laid the foundation for further studies.[trag] (Mus musculus) PubMed
7265.
Several attempts to delete the mahrp2 gene failed, indicating that the protein is essential for parasite survival.[MAHRP2] (Mus musculus) PubMed
7266.
In summary, FlbC is a putative nuclear transcription factor necessary for proper activation of conidiation, and its balanced activity is crucial for governing growth and development in Aspergillus nidulans.[FlbC] (Mus musculus) PubMed
7267.
The authors conclude that DAC1 and DAC3 play distinct roles in subtelomeric gene silencing and that DAC3 represents the first readily druggable target linked to variant surface glycoprotein expression sites control.[DAC1 & DAC3] (Mus musculus) PubMed
7268.
Studies identified the stem-loop precursor structure of miR-363 and 363* followed by their temporal and spatial expression patterns in chicken embryo at the stage of E3.5-6.5 d: [miR-363 and 363*] (Mus musculus) PubMed
7269.
Mutations of R102 cause accumulation of extrachromosomal ribosomal DNA circles and reduce life span, suggesting that histone H2B contributes to longevity. (Mus musculus) PubMed
7270.
These biochemical data suggest that DPAP1 accelerates the production of amino acids from hemoglobin by bridging the gap between the endopeptidase and aminopeptidase activities of the food vacuole.[DPAP1] (Mus musculus) PubMed
7271.
In conclusion, Clostridium botulinum C2 toxin is endocytosed by dynamin-dependent mechanisms and we provide evidence for involvement of clathrin and Rho.[Clostridium botulinum C2 toxin] (Mus musculus) PubMed
7272.
Thus TgSUB1 is involved in micronemal protein processing and regulation of adhesive properties of macromolecular adhesive complexes involved in host cell invasion.[SUB1] (Mus musculus) PubMed
7273.
The three-dimensional (3D) structure of Dnm1 in a GTP-bound state has been determined. (Mus musculus) PubMed
7274.
Vibrio cholerae anaerobic induction of virulence gene expression is controlled by thiol-based switches of virulence regulator AphB [AphB] (Mus musculus) PubMed
7275.
Sum1 and Sok2, which regulate IME1, bind to nonperfect consensuses within nonconserved regions in the sensu stricto Saccharomyces strains.[IME1] (Mus musculus) PubMed
7276.
Rab proteins and PI4P collaborate in the association of secretory compartments with Myo2p.[Myosin V] (Mus musculus) PubMed
7277.
CgPMU2 has neofunctionalized to become a broad range, phosphate starvation-regulated acid phosphatase, which functionally replaces PHO5 in Candida glabrata.[CgPMU2] (Mus musculus) PubMed
7278.
NdeA-B and ndiA encode external and internal alternative NADH dehydrogenases. [NdeA-B, ndiA] (Mus musculus) PubMed
7279.
Purified sialidase released sialic acid from diverse substrates such as mucin, fetuin, epithelial cell glycans and colominic acid (sialidase). (Mus musculus) PubMed
7280.
SPO11 is essential for homologous chromosome pairing and crossover formation. [Spo11] (Mus musculus) PubMed
PbSP interacts with a peptidyl prolyl cis-trans isomerase, calnexin, HSP70 and PWP2. [SP, serine protease] (Mus musculus) PubMed
7283.
OsABF2 functions as a transcriptional regulator that modulates the expression of abiotic stress-responsive genes through an abscissic acid-dependent pathway.[ABF2] (Mus musculus) PubMed
7284.
ACS-3-derived long-chain fatty acyl-CoAs, perhaps incorporated into complex ligands such as phosphoinositides, modulate NHR-25 function, which in turn regulates an endocrine program of lipid uptake and synthesis. [ACS-3] (Mus musculus) PubMed
7285.
The structure of a peptide corresponding to 1.5 units of the PthA repeat domain was solved.[PthA] (Mus musculus) PubMed
7286.
The ClpX stimulates expression of Staphylococcus aureus spa by Rot dependent and independent pathways. [spa, Rot,ClpX] (Mus musculus) PubMed
7287.
Alteration AQP1 Ala163 to aspartate, glutamate, and glutamine blocked passage of water, glycerol, and other organic solutes.[AQP1] (Mus musculus) PubMed
7288.
Molecular dynamics techniques were used to investigate the detailed interactions between the complete tetrameric form of IN and two molecules of the integrase binding domain of LEDGF/p75.[Integrase] (Mus musculus) PubMed
7289.
Two tandem mitochondrial ribosomal protein L27 genes (mtRPL27a and mtRPL27b), both of which are inactive and leads to F(1) pollen sterility in a cross between O. sativa and O. nivara.[mtRPL27a and mtRPL27b] (Mus musculus) PubMed
7290.
analysis of how the SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II C-terminal repeat domain [Spt6] (Mus musculus) PubMed
7291.
The sequence of WciP, a GT2-family glycosyltransferase, indicates that point mutation has compromised linkage specificity, allowing two alternative oligosaccharides to be synthesized.[WciP] (Mus musculus) PubMed
7292.
Trypanosoma brucei TbDNAH10 was silenced using RNA interference and this resulted in immotile flagella, showing no movement except for occasional slight twitches at the tips.[TbDNAH10] (Mus musculus) PubMed
7293.
enzymatic properties of the silkworm Na(+)/K(+)-ATPase are suitable for its growth, despite the differences between dog and silkworm Na(+)/K(+)-ATPases[Na(+)/K(+)ATPase] (Mus musculus) PubMed
7294.
The fhbA gene encoding putative flavohemoglobins expression is correlated to the hyphal growth phenotype. [FhbA] (Mus musculus) PubMed
7295.
an active and water soluble NDH-2 was obtained [NDH-2] (Mus musculus) PubMed
7296.
X-ray crystal structure of the DNA-binding domain of the response regulator WalR; specific interactions of WalR with the target DNA [WalR] (Mus musculus) PubMed
7297.
carbohydrate moieties of arabinogalactan-proteins are degraded by the concerted action of NcAraf1 and Nc6GAL secreted from N. crassa [NcAraf1][Nc6GAL] (Mus musculus) PubMed
7298.
The results presented here implicate plastidic GS2 in proline production during stress and provide interesting insights into the function of proline in response to drought.[glutamine synthetase GS2] (Mus musculus) PubMed
7299.
WAF1 is required for a wide range of developmental events by stabilizing miRNAs and ta-siRNAs. [WAF1] (Mus musculus) PubMed
7300.
Septins are required for proper morphogenesis but dispensable for virulence. [sep1, sep2, sep3, sep4] (Mus musculus) PubMed
7301.
Data showed that EhPCP5 RGD motif is a ligand for alpha(V)beta(3) integrin-mediated adhesion on colonic cells and represents a novel mechanism to trigger an inflammatory response in the pathogenesis of intestinal amebiasis: [EhPCP5] (Mus musculus) PubMed
7302.
The greatwall protein as a new regulator of the DNA damage response plays an important role in recovery from DNA damage. (Mus musculus) PubMed
7303.
SBF and Spt10 cooperate to control the timing of HTA1-HTB1 expression.[Spt10, Swi4] (Mus musculus) PubMed
7304.
Hepatitis B spliced protein (HBSP) interacts with fibrinogen gamma chain (FGG) and inhibits fibrin polymerization and factor XIIIa-mediated fibrin cross-linking. [HBSP] (Mus musculus) PubMed
7305.
LytSR two-component system regulates extracellular murein hydrolase activity, bacterial cell death and pyruvate utilization. [murein hydrolase] (Mus musculus) PubMed
7306.
Data indicate a cooperative role of Aip1 and cofilin in pH-dependent cell migration, and they suggest defective chemotaxis in Ddnhe1(-) cells is determined primarily by loss of cofilin-dependent actin dynamics [Aip1]. (Mus musculus) PubMed
7307.
Leishmania phenylalanine hydroxylase may mitigate but not alleviate Tyrosine auxotrophy, but plays no essential role in the steps of the parasite infectious cycle.[phenylalanine hydroxylase] (Mus musculus) PubMed
7308.
Pb1 encodes an atypical R protein-like protein, which confers resistance to rice blast. [Pb1] (Mus musculus) PubMed
7309.
structural basis and dynamics of precursor recognition by Tom20 [Tom20] (Mus musculus) PubMed
7310.
Results suggest that OsCPK21 is involved in the positive regulation of the signaling pathways that are involved in the response to ABA and salt stress: [OsCPK21] (Mus musculus) PubMed
7311.
Solubilized sterol C24-methyltransferase (24-SMT) was purified to homogeneity from a cell extract of the yeast Candida albicans (Mus musculus) PubMed
7312.
Using Penicillium chrysogenum Pex11, the study shows that this amphipathic helix, termed Pex11-Amph, associates with liposomes in vitro; interaction is evident when liposomes with a content resembling that of peroxisomal membranes are used. [Pex11] (Mus musculus) PubMed
7313.
Thus, HdpA is the first enzyme belonging to the M23-peptidase family able to perform the d,d-carboxypeptidation and regulate cell shape.[HdpA] (Mus musculus) PubMed
7314.
Cdc28 kinase localizes to meiotic chromosomes and is necessary for the formation of the synaptonemal complex. [Cdc28] (Mus musculus) PubMed
7315.
The FLR1 network structure was revised, based on the comparison between simulated and experimental gene expression data.[FLR1] (Mus musculus) PubMed
7316.
Positive torsion in front of the polymerase induces supercoiling (writhe) and is largely resolved by Top2. Negative torsion behind the polymerase induces DNA strand separation and is largely resolved by Top1.[Top1, Top2] (Mus musculus) PubMed
7317.
Ash1 recognition by Cdc4 appears to be mediated by at least three phosphorylation sites that form two redundant diphosphorylated degrons.[Cdc4, Ash1] (Mus musculus) PubMed
7318.
Spt6 regulates transcription by controlling chromatin structure over regulatory regions.[Spt6] (Mus musculus) PubMed
7319.
Sen1 prevents the accumulation of R loop formations and protects the genome from instability. (Mus musculus) PubMed
7320.
Cdc48 functions in conjunction with proteasomes to sustain processive degradation of unstable subunits of some macromolecular protein complexes. (Mus musculus) PubMed
7321.
Mutants lacking functional addB(HP1089} or addA show deficiency in intrachromosomal RecA-dependent homologous recombination. [AddA] (Mus musculus) PubMed
7322.
Ctr2 mutant displayed sensitivity to copper starvation and defects in polysaccharide capsule production and increased phagocytosis. [Ctr2] (Mus musculus) PubMed
7323.
Deletion and overexpression of flbE result in developmental defects.[FlbE] (Mus musculus) PubMed
7324.
hydrolysis of p-nitrophenyl-beta-1,4-cellobioside (pNP-G2) by the catalytic domain of the retaining-family 5-2 endocellulase Cel5A from Thermobifida fusca [Cel5Acd] (Mus musculus) PubMed
7325.
Deletion and overexpression of flbE result in developmental defects.[FlbE] (Mus musculus) PubMed
7326.
flbB encodes two basic leucine zipper domain (bZIP) proteins required for proper asexual development and gliotoxin production (flbB) (Mus musculus) PubMed
7327.
Thus, AcuM represses SreA and thereby induces iron acquisition, a process that is essential for the maximal virulence of Aspergillus fumigatus.[AcuM & SreA] (Mus musculus) PubMed
7328.
Mass spectrometry analysis identified the the 47-kDa protein as the putative chlorophenol reductive dehalogenase CprA3.[CprA3] (Mus musculus) PubMed
7329.
DSM2 contributes to control of the xanthophyll cycle and ABA synthesis, both of which play critical roles in the establishment of drought resistance in rice. [DSM2] (Mus musculus) PubMed
7330.
Genetic analysis determined a single recessive gene controls male sterility in Guangzhan63S variety of rice. [ptgms2-1] (Mus musculus) PubMed
7331.
The 108N, 51I and 437G mutations prevail in the populations of P. falciparum, indicating a cumulative effect of mutations (Mus musculus) PubMed
7332.
Pot1 and Rqh1 are required for efficient chromosome segregation.[Pot1, Rqh1] (Mus musculus) PubMed
7333.
Mre11 nuclease activity and Ctp1 are critical for efficient Rad3-to-Chk1 signaling.[Mre11, Ctp1, Chk1, Rad3, Tel1] (Mus musculus) PubMed
7334.
The histone complex containing Asf1 and HIRA has a role in global histone deacetylation and transcriptional silencing. [2 genes] (Mus musculus) PubMed
7335.
Interaction between two chromodomains (CD) causes Swi6 to tetramerize on a nucleosome, generating two vacant CD sticky ends. (Mus musculus) PubMed
7336.
levels of IR2 and IR3 mRNA declined from pre-hatch (29 days post-fertilization, dpf) to post-hatch (68-90 dpf), whereas levels of IR1 and IR4 remained relatively unchanged[insulin receptor] (Mus musculus) PubMed
7337.
The recessive lss mutation reduces expression of the SUNN gene. [SUNN] (Mus musculus) PubMed
7338.
2-keto-3-deoxy-D-manno-octulosonic acid (Kdo) cleavage requires simultaneous expression of both proteins KdoH1 and KdoH2.[KdoH1 and KdoH2] (Mus musculus) PubMed
7339.
Together, these results suggest a role for the Nik system in the urinary tract infection by S. aureus, probably due to the urease-mediated pH increase of the urine.[NikA & NikBCDE] (Mus musculus) PubMed
OsDRP2B is a typical dynamin-related protein-2 family member. Mutants have lower cellulose content and altered cell wall composition. [OsDRP2B] (Mus musculus) PubMed
7342.
OsMPK6 regulates systemic acquired resistance in response to Xanthomonas oryzae infection. [OsMPK6] (Mus musculus) PubMed
7343.
The activity of UreA is down-regulated post-translationally by ammonium-promoted endocytosis. [UreA] (Mus musculus) PubMed
7344.
Data show that BcsK(C)/BcsL(B) interaction is essential for the T6SS activity in B. cenocepacia K56-2: [BcsK(C) and BcsL(B)] (Mus musculus) PubMed
7345.
Crystal structure of RNAP bound to Gfh1: results reveal that Gfh1 inhibits transcription by preventing NTP binding and freezing RNAP in the alternative structural state [Gfh1] (Mus musculus) PubMed
Mutations at the pore-helix position Glu71 of KcsA unmask a series of kinetically distinct modes of gating in a side chain-specific way. [KcsA] (Mus musculus) PubMed
7348.
Substrates are recruited to the Anaphase-promoting complex by binding to a bipartite substrate receptor composed of Cdh1 and Doc1. [2 genes - Cdh1, Doc1] (Mus musculus) PubMed
7349.
Dcr1 physically associates with some euchromatic genes, noncoding RNA genes and retrotransposon long terminal repeats, and that this association is independent of the Clr4 histone methyltransferase. (Mus musculus) PubMed
7350.
phoPQ mutants were more resistant to strong acidic conditions (pH 4.5 or 5) than that of the wild-type (WT) strain, suggesting that this system in Erwinia amylovora may negatively regulate acid resistance gene expression.[PhoPQ] (Mus musculus) PubMed
7351.
Data demonstrate that miR-275 is indispensable for blood-meal-activated processes: [miR-275] (Mus musculus) PubMed
7352.
The dynamics of matefin/SUN-1 aggregates remained unchanged throughout leptonene/zygotene, despite the progression of pairing.[KASH] (Mus musculus) PubMed
7353.
This study defines a new regulator, CHB-3, in the trafficking process and also shows the importance of ciliary targeting of the signaling molecule, GCY-12, in sensory-dependent body size regulation in C. elegans.[CBH-3, GCY-12] (Mus musculus) PubMed
7354.
SIC (streptococcal inhibitor of complement) interferes with the activation of the contact system and blocks the activity of antibacterial peptides generated through complement and contact activation [SIC] (Mus musculus) PubMed
7355.
The ability of Escherichia coli K-12 MG1655 to overcome the loss of phosphoglucose isomerase (pgi) by adaptively evolving ten replicates of E. coli lacking pgi, was investigated.[Pgi] (Mus musculus) PubMed
7356.
We demonstrate through sequence and structural comparisons that HugZ belongs to a new heme-binding protein family with a split-barrel fold[HUGZ] (Mus musculus) PubMed
7357.
Atg9 has all the prerequisites to be a major factor in regulating the supply of at least part of the membranes necessary for the formation and expansion of nascent autophagosomes.[Atg9] (Mus musculus) PubMed
7358.
GAP40 is a polytopic inner membrane complex protein that belongs to the glideosome. [GAP40] (Mus musculus) PubMed
7359.
DAF-25 is required for proper DAF-11 ciliary localization.[DAF-25, DAF11] (Mus musculus) PubMed
7360.
These studies pinpoint RACK-1 as a component of a novel signaling pathway involving Rac GTPases and UNC-115/abLIM.[UNC-115, CED-10] (Mus musculus) PubMed
7361.
A marker at the 5' untranslated region of the GARS-AIRS-GART gene was significant for inosine 5'-monophosphate content (GARS-AIRS-GART). (Mus musculus) PubMed
7362.
Analysis of the mVbeta8.2-SEG interface allowed us to explain the higher affinity of this complex compared with the others, which may account for the early activation of T-cells bearing mVbeta8.2 by SEG[SEG] (Mus musculus) PubMed
7363.
Phosphorylation of Atg1 on multiple sites provides critical mechanisms to regulate Atg1 function in autophagy and the Cvt pathway.[Atg1] (Mus musculus) PubMed
7364.
RACK1 stimulates the translation arrest that is induced by basic amino-acid sequences that leads to endonucleolytic cleavage of the mRNA, as well as to co-translational protein degradation.[RACK1] (Mus musculus) PubMed
7365.
These data suggest a model wherein Dpb3 and Dpb4 do not directly influence replication fidelity per se, but rather contribute to normal replication fork progression.[Dpb3, Dpb4] (Mus musculus) PubMed
7366.
gp41 may destabilize viral membrane, priming the virus for fusion with a target cell.[gp41] (Mus musculus) PubMed
7367.
The results indicate that the nucleocapsid locally melts the TAR RNA and RRE-IIB RNA hairpins, whereas Tat and Rev may strengthen the hairpin structures through specific binding interactions.[Nucleocapsid] (Mus musculus) PubMed
7368.
The conformational change of adenylate kinase (AK) between open and closed forms by conducting five all-atom molecular-dynamics simulations, each of 100 ns duration, was studied.[Adenylate kinase] (Mus musculus) PubMed
7369.
Data show that Im7 glycosylation influences folding by modulating the local conformational preferences of the glycosylated sequence: [Im7] (Mus musculus) PubMed
7370.
Results show that rhcmvIL-10 alters the earliest host responses to viral antigens by dampening the magnitude and specificity of innate effector cells to primary RhCMV infection: [rhcmvIL-10; UL111A] (Mus musculus) PubMed
7371.
study reports that rice cells require a LysM receptor-like kinase, OsCERK1, in addition to CEBiP, for chitin signaling[CEBiP] [CERK1] (Mus musculus) PubMed
7372.
identified mutations in both the gyrA and parC genes of four ofloxacin- and ciprofloxacin-resistant S. pneumoniae isolates; mutations were found in the gyrA gene at positions Ser81Phe, Glu85Gly, Glu85Lys and in the parC gene at Ser79Tyr [gyrA and parC] (Mus musculus) PubMed
7373.
Combined resistance to lincosamides, pleuromutilins and streptogramin A antibiotics is associated with the resistance genes vga(A)5 and vga(C), both of which are located on plasmids in MRSA from swine. [vga(A)] (Mus musculus) PubMed
7374.
Data show, by performing site-directed mutagenesis of chimeric chicken alpha7/mouse 5-hydroxytryptamine 3 receptor-channel complex, that the allosterically potentiating ligand binding site is different from the positive allosteric modulators binding site. (Mus musculus) PubMed
7375.
The relative position between the highly conserved GXXXG motif and an arginine residue around the gp41 MSD alpha-helix is critical for intracellular trafficking of HIV-1 Env. [gp41] (Mus musculus) PubMed
7376.
ATM and ATR homologes(ataxia telangiestasia muted proteins) of Neurospora crassa regulate independent pathways and are essential for normal cell growth and maintenance of chromosome integrity. [ATM][ATR] (Mus musculus) PubMed
7377.
study of the transcription of BM109, characterized its structural localization and the protein expression pattern [Nm109] (Mus musculus) PubMed
7378.
Mutation of the ZEBRA2 gene results in the accumulation of all-trans-lycopene precursor, prolycopene (7Z,9Z,7'Z,9'Z tetra cis-lycopene), in dark-grown zebra2 tissues[ZEBRA2] (Mus musculus) PubMed
7379.
no consistent relationship between growth rate and resistance phenotypes among the DHFR alleles [DHFR] (Mus musculus) PubMed
7380.
In combination with the overproduction of the chromosomal AmpC enzyme, the loss of OmpF may have played a role in the acquisition of meropenem resistance. [AmpC] (Mus musculus) PubMed
7381.
GacA regulates the virulence in an iron-dependent manner. [GacA] (Mus musculus) PubMed
7382.
CcrAB genes are expressed in E. faecium and are widely distributed in the other Enterococcus. [CcrAB] (Mus musculus) PubMed
7383.
FSY1 was repressed by high concentrations of glucose or fructose and was highly expressed on ethanol as the sole carbon source. [FSY1] (Mus musculus) PubMed
7384.
Myb-4controls a hierarchical network comprised of several regulatory sub-clusters associated with cellular defense and rescue, metabolism and development [OsMyb4] (Mus musculus) PubMed
7385.
the identification of a novel conjugative plasmid carrying the cfr gene indicates the ability of cfr to spread to other MRSA strains [cfr] (Mus musculus) PubMed
7386.
Both NP and PB2 contribute to the high pathogenicity of the H5N1 HPAI viruses in chickens, and valine at position 105 of NP may be one of the determinants for adaptation of avian influenza viruses from ducks to chickens. [NP, PB2] (Mus musculus) PubMed
7387.
YshA is an unknown outer-membrane protein from Salmonella typhimurium [YshA] (Mus musculus) PubMed
7388.
Unitary conductance, dwell times, and open probability of the K(+) channel KcsA as a function of temperature in lipid bilayers were measured.[KcsA] (Mus musculus) PubMed
7389.
NatB deletion led to a very significant change in protein phosphorylation.[NatB] (Mus musculus) PubMed
7390.
These results indicate that post-transcriptional control is important in the myo1Delta stress response and possibly other stresses in yeast.[Myo1] (Mus musculus) PubMed
7391.
All rate constants for the multistep reaction between EF-Tu (wild-type and two mutants), EF-Ts, GDP, and GTP were determined using the stopped-flow technique.[EF-Tu] (Mus musculus) PubMed
7392.
the co-crystal structure of the CusBA efflux complex, showing that the transporter (or pump) CusA, which is present as a trimer, interacts with six CusB protomers and that the periplasmic domain of CusA is involved in these interactions [CusA & CusB] (Mus musculus) PubMed
7393.
The linker of the Trichoderma reesei Family 7 cellobiohydrolase (Cel7A) is examined by simulation.[Cel7A] (Mus musculus) PubMed
7394.
B. mori 3-dehydroecdysone 3beta-reductase (3DE 3beta-reductase) maintains ecdysone titer through converting 3DE to ecdysone. [3-dehydroecdysone 3beta-reductase/3DE 3beta-reductase] (Mus musculus) PubMed
7395.
Charged residues in the cytoplasmic loop of MotA are required for assembly of the flagellar motor. {motA] (Mus musculus) PubMed
7396.
V. cholerae mutant lacking TarA is compromised for mouse colonization. [TarA] (Mus musculus) PubMed
7397.
NleH1 or nleH2 decreased IKK-beta-induced NF-kappaB activity and attenuated TNF-alpha-induced degradation of phospho-IkappaBalpha. [NleH1 and NleH] (Mus musculus) PubMed
7398.
This investigation shows that minor capsid proteins, BDLF1 and BORF1, form a triplex similar to that of HSV-1, which interacts with VCA to connect capsomers on a capsid. {BDLF1, BORF1] (Mus musculus) PubMed
7399.
Reported here is the gp23.1 crystal structure at 1.6 A resolution, a protein that lacks sequence identity to any known protein. [gp23.1] (Mus musculus) PubMed
7400.
The Snf7 binds Bro1 domain enhances the stability of ESCRT-III by inhibiting Vps4-mediated disassembly in vivo and in vitro. [Bro1 & Snf7] (Mus musculus) PubMed
7401.
The first thermodynamic study on the conformational equilibrium and stability of NS3 and the effect of zinc on such equilibrium is presented here.[NS3] (Mus musculus) PubMed
7402.
The product of the rssC gene is predicted to be mainly responsible for fatty-acid biosynthesis of the Serratia marcescens outer membrane.[rssC] (Mus musculus) PubMed
7403.
Deletion of ptkA had a lethal effect in later stages of vegetative growth and completely impeded asexual development. [ptkA] (Mus musculus) PubMed
7404.
Detailed kinetic analysis using 3'-labeled DNA indicates that endonuclease V also possesses non-specific 5'-exonuclease activity (endonuclease V) (Mus musculus) PubMed
7405.
Overexpression of rsmA restores production of sterigmatocystin. [rsmA] (Mus musculus) PubMed
7406.
The DR7B protein bound to human p53 protein. p105-p50/p65 mRNA expression and activation of the NFkappaB complex were increased when DR7B was expressed.(HHV-6 DR7B protein) (Mus musculus) PubMed
7407.
HI assays against H1N1pdm demonstrate that the D131E and S186P mutations caused minor antigenic changes and, likely, affected receptor binding.[Hemagglutinin;A/California/04/09(H1N1)] (Mus musculus) PubMed
7408.
findings support a model in which PrrC toxicity is contingent on head-to-tail dimerization of the NTPase domains to form two composite NTP phosphohydrolase sites (PrrC). (Mus musculus) PubMed
7409.
nsrR mutant constitutively overexpresses Hmp is hypersensitive to peroxynitrite. [Hmp] (Mus musculus) PubMed
7410.
OsMADS6 is highly expressed in flower and endosperm; study shows that H3K27 is trimethylated in tissues where OsMADS6 is silenced, and that H3K36 is trimethylated in tissues where OsMADS6 is highly activated. [MADS6] (Mus musculus) PubMed
7411.
His160 and Asn191 were found to be essential for catalysis and Asn182 to be required for stability of EndA (EndA). (Mus musculus) PubMed
7412.
Data show that replacement of Tyr253 by alanine in alternative oxidase (AOX) resulted in a 72% loss of activity suggesting that the benzoquinone group and not hydroxyl group is important for quinol binding: [AOX] (Mus musculus) PubMed
7413.
A structure determination for the monomeric form using traditional NMR methods is presented, followed by a dimer structure determination using docking under orientation constraints from residual dipolar couplings data. (Mus musculus) PubMed
7414.
Fet3 protein lacking any one of the core glycan units is found in an intracellular high-molecular mass species resolvable by blue native gel electrophoresis. [Fet3] (Mus musculus) PubMed
7415.
Transcription factor genes YAP1, PDR1, PDR3, RPN4, and HSF1 appeared to play key regulatory rules for global adaptation in the yeast S. cerevisiae.[YAP1, PDR1, PDR3, RPN4, HSF1] (Mus musculus) PubMed
7416.
Expression of hbz resulted in lower levels of p30(II) mRNA.[hbz & p30II] (Mus musculus) PubMed
7417.
RcsB protein represses rcsD gene expression by binding directly to the P promoter, negatively autoregulating the RcsCDB system. [RcsD] (Mus musculus) PubMed
7418.
KU70 homologue (NkuA) and the heterochromatin-associated proteins HepA, ClrD and HdaA were partially required for transgene silencing. [NkuA] (Mus musculus) PubMed
7419.
zinc finger structure and pol eta regulation [polymerase eta] (Mus musculus) PubMed
7420.
The SunB is essential for accurate prestalk/prespore differentiation during Dictyostelium development and that its cell-type dependent localization is regulated by a Dd-STATa-mediated signaling pathway.(SunB protein) (Mus musculus) PubMed
7421.
Taken together, these results indicate that CYP51A is required for efficient conidiogenesis, full virulence and for mediating DMI sensitivity by the rice blast fungus.[CYP51A] (Mus musculus) PubMed
7422.
The interaction of streptococcal pyrogenic exotoxin B (SpeB) with alpha 1-antitrypsin in vitro and its effects in a mouse model of systemic infection are reported.[SpeB] (Mus musculus) PubMed
7423.
The results suggest that the position of the prion domain affects the ability of Ure2 to form fibrils primarily due to effects on its flexibility.[Ure2] (Mus musculus) PubMed
7424.
Different non-structural protein 1 (NS1) of influenza viruses, one from allele A (H10N4) and another from allele B(H10N7), show different abilities to suppress the type I interferon beta expression. (Mus musculus) PubMed
7425.
pathogenicity test for E058 strain and E058 (delta aes-31) strain showed that the mutant had a higher mortality (75%) to 35-day-old specific pathogen-free (SPF) chicks than that of E058 (62.5%)[ aes-31 ] (Mus musculus) PubMed
7426.
This work reveals Ustilago maydis Rco1 as the first eukaryotic resveratrol cleavage enzyme identified so far.[Rco1] (Mus musculus) PubMed
7427.
[2-KPCC, 2-ketopropyl CoM oxidoreductase (carboxylating), EC 1.2.7.-] crystal structure of 2-KPCC at 1.9 A resolution; structure with substrates/ligands bound (CO2, 2-ketopropyl CoM); catalytic mechanisms discussed (Mus musculus) PubMed
7428.
[GcpE, hydroxymethylbutenyl 4-diphosphate synthase] X-ray structure at 2.5 A resolution; putative substrate binding site; binding mode of [4Fe-4S] cluster; catalytic mechanisms discussed (Mus musculus) PubMed
7429.
Inactivation of PI3K enhances Legionella infection and suppresses the protective effect of Nramp1 overexpression. [ Nramp1 ] (Mus musculus) PubMed
7430.
Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner. [Atg8] (Mus musculus) PubMed
7431.
Abch1 is a novel ATP binding cassette (ABC) transporter found in fish. This study is an initial characterisation of this transporter using phylogenetic analyses, membrane topology prediction and determination of tissue expression pattern in zebrafish (Mus musculus) PubMed
7432.
present complete MRP1 (ABCC1) and partial MRP3 (ABCC3) cDNAs from rainbow trout (Oncorhynchus mykiss). [ABCC1 protein] (Mus musculus) PubMed
7433.
The concerted activity of p8 and p12 is essential for the persistence of virus infected cells in the host.[p8, p12] (Mus musculus) PubMed
7434.
The gat1 mutant exhibited impaired growth on all amino acids tested as sole nitrogen sources, with the exception of arginine and proline.[GAT1] (Mus musculus) PubMed
7435.
The data suggest that three different Aedes aegypti midgut proteins, i.e., cadherin, AaeALP1, and AaeAPN1, are involved in Cry11Ba binding to Aedes aegypti midgut brush border membranes.[AaeALP1] (Mus musculus) PubMed
7436.
This study study demonstrated that the lipid kinase Vps34p is already associated with peroxisomes during biogenesis.[Vps34p] (Mus musculus) PubMed
7437.
DOT1A dimethylated H3K79, DOT1B trimethylated H3K79 even in the absence of dimethylation by DOT1A. [DOT1A, DOT1B] (Mus musculus) PubMed
7438.
The authors show that an anti-sigma factor antagonist BldG associates with RshA and negatively regulates its activity.[BldG] (Mus musculus) PubMed
7439.
Rsr1 also exhibits heterotypic interaction with the Cdc42 GTPase in vivo.[Rsr1, Cdc42] (Mus musculus) PubMed
7440.
The translational regulation of the most highly osmostress-regulated mRNAs was more strongly dependent on the stress-activated protein kinases Hog1 and Rck2 than the transcriptional regulation.[Hog1] (Mus musculus) PubMed
The cell-surface lipoprotein SiaA, a component of the SiaABC transporter, acts as the primary receptor for heme in the infamous human pathogen Streptococcus pyogenes. (Mus musculus) PubMed
7443.
The purified Rvs161-Rvs167 complex binds to liposomes in a curvature-independent manner and promotes tubule formation in vitro.[Rvs161, Rvs167] (Mus musculus) PubMed
7444.
The complex functions of HBZ modulate T-cells, and promote their proliferation, which is likely indispensable for leukemogenesis by HTLV-1.[HBZ] (Mus musculus) PubMed
7445.
The splicing activity of the PRP8 intein from the Blastomyces dermatitidis, Emmonsia parva and Paracoccidioides brasiliensis species complex was demonstrated in a non-native protein context in Escherichia coli. (Mus musculus) PubMed
7446.
UspB, a member of the RpoS regulon, is required for proper DNA repair [UspB][RuvC][RpoS] (Mus musculus) PubMed
7447.
These results indicate that different sterol demethylation inhibitor fungicides target different CYP51 proteins in Fusarium graminearum and that a mixture of fungicides can result in synergistic effects.[CYP51] (Mus musculus) PubMed
7448.
In conclusion, the Ste50 adaptor protein controls sexual differentiation of Cryptococcus neoformans via the pheromone-responsive MAPK pathway but is not required for virulence.[Ste50] (Mus musculus) PubMed
7449.
Data show that CENH3 expression patterns shed more light on the inter-coordination between varied centromeric DNA sequences and highly conserved kinetochore protein in synthesized allopolyploids of Oryza: [CENH3] (Mus musculus) PubMed
7450.
The authors propose a K(+)-H(+) symporter that, under certain conditions may work as a K(+)-Na(+) transporter, as the mechanism driving K(+) influx mediated by DhHak1p.[Hak1] (Mus musculus) PubMed
7451.
A short conserved C-terminal sequence in Mto1, termed MASC, is important for targeting Mto1 to multiple distinct microtubule organizing centers (MTOCs). (Mus musculus) PubMed
7452.
The present review is focused on the current knowledge of p13, an HTLV-1 accessory protein targeted to the inner mitochondrial membrane and, under certain conditions, to the nucleus.[p13] (Mus musculus) PubMed
7453.
This work defines a new role for arrestins in membrane trafficking and offers insight into how alpha-arrestins coordinate signaling events with protein trafficking.[Aly1, Aly2] (Mus musculus) PubMed
7454.
SifA may use a similar mode of action via Rho proteins to alter yeast peroxisomal and mammalian endosomal membranes. [Rho1] (Mus musculus) PubMed
7455.
ROS production by mitochondrial mutants and found that isp-1 and nuo-6 mutants have increased generation of the superoxide anion but not increased levels of other ROS and that this increase is necessary and sufficient for longevity.[Nuo-6] (Mus musculus) PubMed
7456.
(photoactivated adenylyl cyclase alpha; PACalpha) PACalpha is expressed in cholinergic neurons and is used to determine changes in neurotransmitter release and behavioral effects. (Mus musculus) PubMed
7457.
Hsp33 crystal structure was determined at 2.40A resolution.[Hsp33] (Mus musculus) PubMed
7458.
The crystal structure of pyridoxal phosphate-bound SpeA from Campylobacter jejuni is reported at 3.0A resolution and that of Escherichia coli SpeA in complex with a sulfate ion is reported at 3.1A resolution.[SpeA] (Mus musculus) PubMed
7459.
The crystallographic structures of BamC, BamD and BamE, each lacking the N-terminal membrane anchor, are described.[BamC, BamD, BamE] (Mus musculus) PubMed
7460.
Crystals of C-terminally His6-tagged Wzi diffracted to 2.8A resolution.[Wzi] (Mus musculus) PubMed
7461.
During synthesis of siderophore enterobactin in iron-starved strain BW25113 cells, tetrameric EntA optimally interacts with EntE forming a specific complex with EntE, resulting in an enhancement of EntE activity. [EntA] (Mus musculus) PubMed
7462.
Rice MEL2 protein discovered in this study shows partial similarity with human proline-rich RRM protein, deleted in Azoospermia-Associated Protein1 (DAZAP1), though MEL2 also possesses ankyrin repeats and a RING finger motif[MEL2] (Mus musculus) PubMed
7463.
The crystal structure of pyridoxal phosphate-bound SpeA from Campylobacter jejuni is reported at 3.0A resolution and that of Escherichia coli SpeA in complex with a sulfate ion is reported at 3.1A resolution.[SpeA] (Mus musculus) PubMed
7464.
find that Clr5 controls gene expression at multiple chromosomal locations in addition to affecting the mating-type region[Clr5 ] (Mus musculus) PubMed
7465.
BoNT/D receptor binding domain was crystallized and the crystals diffracted to 1.65A resolution.[BoNT/D] (Mus musculus) PubMed
7466.
three-dimensional crystal structures of SgrAI bound to cleaved primary-site DNA and Mg(2)(+) and bound to secondary-site DNA with either Mg(2)(+) or Ca(2)(+) are presented[SgrAI ] (Mus musculus) PubMed
7467.
Virulent T. gondii strain ROP18 kinase phosphorylates host Irga6 at two threonines in the nucleotide-binding domain, biochemically inactivating the GTPase and inhibiting its accumulation and action at the T. gondii parasitophorous vacuole membrane.[ROP18] (Mus musculus) PubMed
7468.
VacA induces apoptosis mediated by BAX and BAK but additionally induces the translocation of BAX to mitochondrial endosomes[VacA induces apoptosis mediated by BAX and BAK but additionally induces the translocation of BAX to mitochondrial endosomes [VacA] (Mus musculus) PubMed
7469.
Data show that the OsMKK4-OsMPK6 cascade plays a crucial role in reprogramming plant metabolism during MAMP-triggered defense responses: [OsMKK4 & OsMPK6] (Mus musculus) PubMed
7470.
the GH57 GBE possesses about 4% hydrolytic activity with amylose and in vitro forms a glucan product with a novel fine structure, demonstrating that the GH57 GBE is clearly different from the GH13 GBEs characterized to date. [GH57 GBE] (Mus musculus) PubMed
7471.
Two LjCLE genes, LjCLE19 and 20, were up-regulated specifically and greatly in roots of L. japonicus by phosphate addition to the hydroponic solution.[LjCLE19,LjCLE20] (Mus musculus) PubMed
7472.
These results illustrate that over-expression of osa-MIR393 can negatively regulate rice salt-alkali stress tolerance.[osa-MIR393] (Mus musculus) PubMed
7473.
Interferon tau induces expression of DEAD box polypeptide 58 (DDX58) and phospholipid scramblase 1 (PLSCR1) in ovine endometrial cells via the classical STAT1-mediated cell signaling pathway. (Mus musculus) PubMed
7474.
Both Lgl and Dsh are required for normal apical-basal polarity of Xenopus ectodermal cells. (Mus musculus) PubMed
7475.
CHAT-1 and TAT-1 maintain membrane phosphatidylserine asymmetry, thus promoting membrane tubulation and regulating endocytic sorting and recycling. [CHAT1] (Mus musculus) PubMed
7476.
Study reports the crystal structure of a UvrA protein in complex with a chemically modified oligonucleotide; shows that the UvrA dimer does not contact the site of lesion directly, but rather binds the DNA regions on both sides of the modification.[UvrA] (Mus musculus) PubMed
7477.
Formation of the outer membrane translocon for cellular import of the nuclease colicins is a demonstrably dynamic process, because it depends on lateral diffusion of BtuB and collisional interaction with relatively immobile OmpF.[BtuB, OmpF] (Mus musculus) PubMed
7478.
LaeA control fungal morphological, chemical development, and interactions of the velvet regulators. [LaeA] (Mus musculus) PubMed
7479.
OsRAN2 regulats cold resistance in rice by maintaining cell division through promoting the normal export of intranuclear tubulin at the end of mitosis. (Mus musculus) PubMed
7480.
OsRab5a plays an essential role in trafficking of storage protein to protein body II. [OsRab5a] (Mus musculus) PubMed
7481.
crystal structure of Hbp shows that the protein carries a serine protease domain and a small domain of 75 residues which is inserted into the long beta-helix characteristic of autotransporter passenger proteins[Hbp/Tsh, UniProt reference code O88093] (Mus musculus) PubMed
7482.
Certain TaGS2 haplotypes may be valuable in breeding wheat varieties with improved agronomic performance and Nitrogen-use efficiency.[Ta-GS2] (Mus musculus) PubMed
7483.
A major BiP cochaperone in antibody folding, ERdj3, modulated the conformational space of BiP in a nucleotide-dependent manner, placing the lid subdomain in an open, protein-accepting state.[ERdj3] (Mus musculus) PubMed
7484.
Interferon tau stimulated expression of N-myc interactor gene mRNA in 2fTGH (ie, in a STAT1-dependent manner), but not in U3A (STAT1-null) cells.[N-myc interactor gene, IFN tau] (Mus musculus) PubMed
7485.
The substrate cleavage pattern monitored by capillary zone electrophoresis showed that TpAraF is a classical exo-acting enzyme producing arabinose as its end-product.[AraF] (Mus musculus) PubMed
7486.
[Isc1, inositol phospho-sphingolipid-phospholipase C 1] Isc1 exhibits only IPC-PLC activity (not SM-PLC as seen in homologous enzymes in other species). Isc1 regulates metabolism/accumulation of complex sphingolipids and ceramides. (Mus musculus) PubMed
7487.
[Isc1, inositol phospho-sphingolipid-phospholipase C 1] Isc1 exhibits only IPC-PLC activity (not SM-PLC as seen in homologous enzymes in other species). (Mus musculus) PubMed
7488.
INTERMEDIUM-C, a modifier of lateral spikelet fertility in barley, is an ortholog of the maize domestication gene TEOSINTE BRANCHED 1 [TEOSINTE BRANCHED 1] (Mus musculus) PubMed
7489.
Despite overall similarity of Xenotropic MuLV-related virus VP62 protease to other retropepsins, the topology of its dimer interface more closely resembles those of the monomeric, pepsin-like enzymes.[protease] (Mus musculus) PubMed
7490.
Variation in SsIIa enzyme activity is associated with the cohesiveness of rice grains when cooked.[SsIIa] (Mus musculus) PubMed
7491.
Our observations confirm that in contrast to its homologues in other organisms, Mip1 can function as a single-subunit replicative polymerase. [Mip1] (Mus musculus) PubMed
7492.
Sumoylation of T. brucei Topoisomerase-II alpha is not required for centromere-specific cleavage activity (Topoisomerase-II alpha). (Mus musculus) PubMed
7493.
Substance P and CGRP correlate with the occurrence and development of allergic rhinitis. [Substance P] (Mus musculus) PubMed
7494.
The authors found that simultaneous mutations at three positions (E67S/E74S/E75S) of NS2/NEP were important for inhibition of influenza viral polymerase activity.[NS2] (Mus musculus) PubMed
7495.
The study describes the analysis of the folding behavior of 12 different alanine-scanning mutants of DsbB. [DsbB] (Mus musculus) PubMed
7496.
The authors found that insertions of as many as twenty residues after the twelfth residue of murine leukemia virus nucleocapsid yielded proteins that directed the efficient assembly of virus particles.[nucleocapsid] (Mus musculus) PubMed
7497.
Gene disruption established that Dur3, encoded by orf 19.781, is the predominant urea transporter.[Dur3] (Mus musculus) PubMed
7498.
Lupeol synthase, encoded by OSC3, and its product, lupeol, have a role in developing roots and nodules in Lotus japonicus. (Mus musculus) PubMed
7499.
Depolarization of GlyCl-expressing cells induces these drastic changes in melanocyte behavior via a serotonin-transporter-dependent increase of extracellular serotonin (Mus musculus) PubMed
7500.
CHLalphaGcT is originally synthesized in the cytoplasm of H. pylori as an inactive form and then activated when it is associated with the cell membrane [cholesterol alpha-glucosyltransferase] (Mus musculus) PubMed
7501.
Changes in extracellular pH result in altered transcription of BTN1.[Btn1] (Mus musculus) PubMed
7502.
These findings suggest that the movement of broad bean wilt virus 2 between cells is mediated by the tubular structures that contain the VP37 protein, and the VP37 protein itself is capable of inducing these tubule-like structures in cells.[VP37] (Mus musculus) PubMed
7503.
One gene encodes a UDP-xylose synthase (Uxs) that converts UDP-glucuronic acid to UDP-xylose, and the second encodes a UDP-xylose 4-epimerase (Uxe) that interconverts UDP-xylose and UDP-arabinose.[Uxs & Uxe] (Mus musculus) PubMed
7504.
While characterizing the cDNAs, fortuitous mutations at NS2A position 46 and NS5 position 836 were found to affect viral production.[NS2A & NS5] (Mus musculus) PubMed
7505.
Several backcross derivatives (hexaploid) possessing variable sized Sr22-carrying segments were used in this study to identify a closely linked DNA marker. [Sr22] (Mus musculus) PubMed
7506.
TaGW2 was located in homologous group 6 chromosomes.[TaGW2] (Mus musculus) PubMed
7507.
The slow-rusting gene(s) Lr67/Yr46 can be utilized in combination with other slow-rusting genes to develop high levels of durable adult plant resistance to leaf rust and stripe rust in wheat.[Lr67, Yr46] (Mus musculus) PubMed
7508.
Entamoeba histolytica holotransferrin-binding protein was identified by MS/MS analysis and database searches as acetaldehyde/alcohol dehydrogenase-2 (EhADH2), an iron-dependent enzyme.[ADH2] (Mus musculus) PubMed
7509.
OsHMA3 was identified as the gene that controls root-to-shoot cadmium translocation rates. (Mus musculus) PubMed
7510.
NCC (Slc12a3)is highly expressed in the mefugu kidney but at lower levels in the torafugu kidney. NKCC2 (Slc12a1) is highly expressed in the kidney of mefugu and torafugu. (Slc12a1 and Slc12a3) (Mus musculus) PubMed
7511.
Nuclear magnetic resonance techniques allowed the calculation of the structure of the LytA197-210[ND] peptide, which displayed a beta-hairpin conformation highly similar to that found within the full-length C-LytA module. [LytA] (Mus musculus) PubMed
7512.
Analyzed are the stability and folding of yeast hexokinase isoenzyme ScHxk2 consisting of two domains with a discontinuous peptide sequence. [ScHxk2] (Mus musculus) PubMed
7513.
Deletion of residues 151-158 accelerates the nucleation, growth and fragmentation of amyloid-like aggregates in vitro, and the aggregates formed are able to seed formation of fibrils of the wild-type protein.[Ure2] (Mus musculus) PubMed
7514.
Collectively, this finding suggests that S186 at the N terminal region of PA of swine-origin influenza virus H1N1 is necessary for the protein to function optimally.[PA] (Mus musculus) PubMed
7515.
The membrane-association of PfYkt6.1 was dependent on the presence of a conserved C-terminal CAAX motif (CCSIM).[Ykt6.1] (Mus musculus) PubMed
7516.
Capsid protein could interact with the nuclear import factor importin alpha, suggesting that the CP is possibly imported into the nucleus via an importin alpha-dependent pathway.[capsid protein] (Mus musculus) PubMed
7517.
inactivation and initial interrogation of key oxygenase CmmOIV of the biosynthetic pathway of chromomycin A(3) in Streptomyces griseus ssp. griseus [CmmOIV] (Mus musculus) PubMed
7518.
In this study the authors identified TAF250, an RNA polymerase II complex component, as an essential gene.[TAF250] (Mus musculus) PubMed
7519.
Research into basic-rich sequences that could be indicative of a functional nuclear localization signal led to the identification of a novel nuclear localization signal for TgGCN5-B, RPAENKKRGR.[GCN5-B] (Mus musculus) PubMed
7520.
The data presented here show that NikR may first select its targets by identifying sequences within the previously defined consensus and subsequently establish base-specific contacts to firmly bind DNA, in particular with the fecA3 target.[NikR; fecA3] (Mus musculus) PubMed
7521.
Results describe a molecular switch governing TSHbeta transcription through the circadian clock, linking the circadian clock to the evolution of seasonal timing in mammals [TSHbeta]. (Mus musculus) PubMed
7522.
DPV022 encoded an inhibitor of apoptosis and interacted with cellular Bak and Bax. [DPV022] (Mus musculus) PubMed
7523.
crystal structure of a TrkH; results reveal the molecular basis of K(+) selectivity and suggest a novel gating mechanism for this large and important family of membrane transport proteins [TrkH] (Mus musculus) PubMed
7524.
This study showed that colony spreading of S. aureus involves the agr quorum-sensing system.[agr] (Mus musculus) PubMed
7525.
the ygs gene controls Staphylococcus epidermidis biofilm accumulation and stress resistance[ygs] (Mus musculus) PubMed
7526.
These data provide evidence of the importance of metacaspase processing into an active catalytic domain and of its role in disrupting mitochondria.[metacaspase] (Mus musculus) PubMed
7527.
ORFV121 interacted with NF-kappaB-p65 in the cell cytoplasm and inhibited NF-kappaB-p65 phosphorylation and nuclear translocation. [RelA] (Mus musculus) PubMed
7528.
The functional diversity of VPg is attributable to structural flexibility. [VPg] (Mus musculus) PubMed
7529.
Unsuccessful attempts at disrupting the Pfark-1 gene with a knockout construct further indicate that Pfark-1 is required for parasite growth in red blood cells.[Pfark-1] (Mus musculus) PubMed
7530.
Expressed NS4B protein hydrolyzes both ATP and GTP.[NS4B] (Mus musculus) PubMed
7531.
Thus, in this system, infectious laryngotracheitis virus-miR-I5 decreased infectious laryngotracheitis virus ICP4 mRNA levels via transcript cleavage and degradation.[miR-I5] (Mus musculus) PubMed
7532.
While deletion of espV from C. rodentium did not affect colonization dynamics or fitness in mixed infections, expression of EspV in mammalian cells led to drastic morphological alterations, which were characterized by nuclear condensation[EspV] (Mus musculus) PubMed
7533.
The results here presented are consistent with the importance of the cyclic AMP signalling pathway in regulatory volume decrease and implicate TcrPDEC2 as a specifically localized phosphodiesterase involved in osmoregulation.[TcrPDEC2] (Mus musculus) PubMed
7534.
Expression of Pik-mediated resistance requires the cooperation of two independent coiled-coil nucleotide binding site leucine-rich repeat genes, Pik-1 and Pik-2 (Pik-1 and Pik-2). (Mus musculus) PubMed
7535.
The authors found that a mutant of Brh2 deleted of the non-canonical DNA-binding domain within the N-terminal region is dependent upon the presence of Rad52 for DNA repair activity.[Brh2] (Mus musculus) PubMed
7536.
mitochondrial and cytosolic tryparedoxin peroxidases from T. cruzi are highly efficient peroxidases that reduce hydrogen peroxide and peroxynitrite [ tryparedoxin peroxidase] (Mus musculus) PubMed
7537.
These data show that complex I is not only present in the procyclic stage of Trypanosoma brucei 29-13 strain, but it does participate in electron transport chain.[complex I] (Mus musculus) PubMed
7538.
The authors showed that that the physical interaction of RpfG with two proteins with a diguanylate cyclase (GGDEF) domain, acts to control a sub-set of RpfG-regulated virulence functions.[RpfG] (Mus musculus) PubMed
7539.
ROP18 phosphorylation of immunity related GTPases prevented clearance within inflammatory monocytes and IFN-gamma-activated macrophages, conferring parasite survival in vivo and promoting virulence.[ROP18] (Mus musculus) PubMed
7540.
a potentially important role of calmodulins during early larval development [SmCaM1(03962); SmCaM2(07755)] (Mus musculus) PubMed
7541.
aimed detect Shiga toxins (stx1 and stx2), enterohaemolysin and intimin virulence genes of 11 E. coli O157:H7 strains isolated from faecal samples of 300 clinically healthy Anatolian water buffaloes [stx1, stx2, EhlyA, intimin] (Mus musculus) PubMed
7542.
These observations show that BiP and CRT activities complement each other to supervise a complete and efficient Trypanosoma cruzi CATL folding process.[BiP] (Mus musculus) PubMed
7543.
In general, mutations in the capping enzyme decreasing the activity for GTP methylation also had correspondingly detrimental effects on virus accumulation.[capping enzyme] (Mus musculus) PubMed
7544.
The binding kinetics between single molecules of bacteriophage T7 RNA polymerase and DNA was measured as a function of tension.[RNA polymerase] (Mus musculus) PubMed
7545.
It was found that the asc1 null mutant was avirulent in a mouse model.[Asc1] (Mus musculus) PubMed
7546.
the preferential polarities of Dmc1 and Rad51 strand exchange are different (Dmc1 promotes exchange in the 5'-to-3' and Rad51 promotes exchange in the 3'-to-5' direction relative to the ssDNA region of the DNA substrate [Dmc1, Rad51; no strain specified] (Mus musculus) PubMed
7547.
A computational search assessing electrostatic interactions for multiple azimuthal locations, z-positions, and pseudo-rotations of tropomyosin on F-actin was performed. [F-actin] (Mus musculus) PubMed
7548.
CDPK4 was a typical calcium-dependent protein kinase which had well-conserved N-terminal kinase domain and C-terminal calmodulin-like structure with 4 EF hand motifs for calcium-binding.[CDPK4] (Mus musculus) PubMed
7549.
structure of the C-terminal domain of SpaP (residues 1136-1489) was solved and refined to 2.2 A resolution with six molecules in the asymmetric unit [SpaP] (Mus musculus) PubMed
7550.
Data report the structure of the small laccase from Streptomyces coelicolor determined from a crystal soaked with potassium hexacyanoferrate [K4Fe(CN)6] [laccase]. (Mus musculus) PubMed
7551.
bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 and Notch3, suggesting that ORF2 interfered with the trans-activation potential of Notch.[ORF2] (Mus musculus) PubMed
7552.
Most critical was residue I405 in the thumb domain of the polymerase, which strongly stimulated replication in cell culture by enhancing overall de novo RNA synthesis.[NS5B] (Mus musculus) PubMed
7553.
These data suggest that budding-competent neuraminidase proteins possess an as-yet-unidentified means of counteracting the antiviral restriction factor tetherin and identify a way in which the influenza virus neuraminidase can contribute to virus release. (Mus musculus) PubMed
7554.
crystal structure of SEp22, a DNA-binding protein from starved cells has been determined in two forms: the native state at 1.25 A resolution and an iron-soaked form at 1.30 A resolution [SEp22] (Mus musculus) PubMed
7555.
The SeqA protein could modulate periodically the initiation of replication of the pBR322 plasmid.[SeqA] (Mus musculus) PubMed
7556.
The DROOPING LEAF (DL) gene, a member of the YABBY gene family, promotes midrib formation in the leaf and carpel specification in the flower. [DROOPING LEAF] (Mus musculus) PubMed
7557.
CYP9M10 is linked to permethrin resistance in these strains of C. p. quinquefasciatus, and is likely to be the P450 gene responsible for resistance in these strains.[CYP9M10] (Mus musculus) PubMed
7558.
Data describe the cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase DapL from Chlamydomonas reinhardtii [DapL]. (Mus musculus) PubMed
7559.
The crystal structure of phenylalanyl-tRNA synthetase from E. coli, a class II aminoacyl-tRNA synthetase, complexed with phenylalanine and AMP. [phenylalanyl-tRNA synthetase subunit alpha, beta] (Mus musculus) PubMed
7560.
Analyses of arginase activity show the bmarg-r gene is expressed in male reproductive organs, whereas the bmarg-f gene is expressed in larval and adult nonreproductive organs.[bmarg-r,bmarg-f] (Mus musculus) PubMed
7561.
The structure of CLC of Synechocystis sp. PCC 6803 is nearly identical to that of E. coli. [CLC] (Mus musculus) PubMed
7562.
BC1L4 encodes a COBRA-like protein that exhibits typical structural features of a glycosylphosphatidylinositol-anchor protein. (BC1L4) (Mus musculus) PubMed
7563.
In the present study a homologue of ix was identified in Bombyx mori.[Bmix] (Mus musculus) PubMed
7564.
Conditioning exposure can change the expression of F-actin in guinea pig cochlea. [F-actin] (Mus musculus) PubMed
7565.
Sodium salicylate can promote the protein expression of NF-kappaB in cochlear spiral ganglion cells. [NF-kappaB] (Mus musculus) PubMed
7566.
Crystal structure of the Thermotoga maritima sirtuin, Sir2Tm, bound to a propionylated peptide derived from p53. (Mus musculus) PubMed
7567.
SAM-responsive box acts as a reversible switch modulating expression of the metK gene. [metK] (Mus musculus) PubMed
7568.
Small regulatory RNA FasX enhances streptokinase activity by increasing the stability of the ska mRNA. [FasX] (Mus musculus) PubMed
7569.
Aga1 is essential for appressorium formation and maintenance of the actin cytoskeleton. [Aga1] (Mus musculus) PubMed
7570.
Purified CYP51 exhibited tight binding to azole antifungal agents such as ketoconazole, econazole, fluconazole, or itraconazole, with K(d) values around 0.26-0.84 muM.[CYP51] (Mus musculus) PubMed
7571.
the identification of the glucose sensor Rag4 as a factor essential for oxygen-dependent regulation of the fermentative pathway.[Rag4] (Mus musculus) PubMed
MBF activator Rep2 plays a role in mediating the cell cycle-specific transcription through the recruitment of RNAP-II to the MBF-bound G(1)/S-phase genes. [MBF(DSC1)] (Mus musculus) PubMed
7574.
conservation of insulin/insulin-like growth factor (IGF) functions in developmental speed control [IGF] (Mus musculus) PubMed
7575.
Immediately adjacent positioning of genes can be functionally significant for their coregulated expression of MPP10 and YJR003C. [MPP10; YJR003C] (Mus musculus) PubMed
7576.
study found evidence of three diffusely adherent (DAEC) strains expressing CS20-like molecules [CS20] (Mus musculus) PubMed
7577.
Structural characterization of Escherichia coli BamE, a lipoprotein component of the beta-barrel assembly machinery complex (Mus musculus) PubMed
7578.
UDP-glucose pyrophosphorylase is a regulated enzyme in E. histolytica [UDP-glucose pyrophosphorylase] (Mus musculus) PubMed
7579.
TbrPPX1 represents the T. brucei exopolyphosphatase. It is located throughout the cytoplasm, and its genetic ablation does not produce a dramatic phenotype. [PPX1] (Mus musculus) PubMed
7580.
results show that Rev1's catalytic activity is important in vivo when the cell has to cope with specific DNA lesions, such as N(2)-dG [rev1] (Mus musculus) PubMed
7581.
rnlA-rnlB define a new toxin-antitoxin (TA) system [rnlA][rnlB] (Mus musculus) PubMed
7582.
Although H. pylori infection is associated with higher serum levels of hs-CRP, serum concentrations of this inflammatory marker were not affected by expression of bacterial CagA virulence factor. (Mus musculus) PubMed
7583.
These results demonstrated that RpoE promoted the expression of class-3 flagellar genes and it might be performed by initiating the expression of fliA in S. enterica serovar Typhi under hyperosmotic stress.[rpoE & fliA] (Mus musculus) PubMed
7584.
Results describe an intragenic suppressor mutant for gid1, named Sgd-1, and reveal that gibberellin is not always required for interaction between its receptor, GID1, and DELLA proteins such as SLR1 [gid1, SLR1]. (Mus musculus) PubMed
7585.
Data show that strains of X. oryzae pv oryzae can defeat the recessive resistance of xa13 by the deployment of any one of the alternate major type III TAL effectors PthXo2, PthXo3, or AvrXa7.022, due to the induction of the alternate S gene Os-11N3. (Mus musculus) PubMed
7586.
NTR or AAT6 loss-of-function represent major potential mechanisms of resistance to these drugs [AAT6, NTR] (Mus musculus) PubMed
7587.
Dug1p can recognize a variety of oligopeptides, but has evolved with post-binding screening potential to hydrolyze Cys-Gly peptides selectively.[Dug1p] (Mus musculus) PubMed
applied a dynamic multisubstrate resolution system for the rapid evaluation of lipase performances of cyanohydrin structures[Amano Lipase PS-C-I] (Mus musculus) PubMed
7590.
These data demonstrate that ExsD binds ExsA to block expression of T3SS1 genes, while ExsC binds ExsD to permit expression of T3SS1 genes. [ExsA, ExsC, ExcD] (Mus musculus) PubMed
7591.
Spt2 is required for the major chromatin deposition pathway that uses old histones to refold nucleosomes in the wake of RNA polymerase II at the SRG1-SER3 locus. [SRG1] (Mus musculus) PubMed
7592.
This analysis suggests that the direct activation of a lipid kinase PI4KA by hepatitis C virus NS5A contributes critically to the integrity of the membranous viral replication complex. (Mus musculus) PubMed
7593.
The frequency of URE3 prion occurrence is very low in Kluyveromyces lactis, well below that of the (ure2-) mutation, such that it may even be impossible to obtain this prion.[URE3] (Mus musculus) PubMed
7594.
Pleiotropic effects were less evident in the o7 mutant, but severe in the o2 and o2o7 backgrounds, with large changes in gene expression patterns, affecting a broad range of kernel-expressed genes. [Opaque-7] (Mus musculus) PubMed
7595.
HSP83 protein is involved in protection against heat stress and could be involved in oogenesis during ovarian maturation of T. castaneum. [hsp83] (Mus musculus) PubMed
7596.
These observations suggest that CT703 may be an important regulator for promoting chlamydial productive infection.[CT703] (Mus musculus) PubMed
7597.
Wld-type allene oxide synthase (AOS) from Arabidopsis or rice in fact produces both AOS and hydroperoxide lyase products in a ratio of about 80:15, something that was found only in trace amounts before. (Mus musculus) PubMed
7598.
These results suggest that down-regulation of quorum sensing by excess LsrR can lower Salmonella virulence by hampering Salmonella evasion from oxidative killing within macrophages.[LsrR] (Mus musculus) PubMed
7599.
purification and detailed characterization of a novel helicase from P. falciparum and show that this helicase is a homologue of Dbp5 and DDX19 from yeast and human, respectively[ddp5/DDX19] (Mus musculus) PubMed
7600.
substrate specificity of the enzyme produced in E. coli [CdpA] (Mus musculus) PubMed
7601.
cHSP60- and cHSP10-induced caspase expression, proinflammatory cytokine production and apoptosis of primary cervical epithelial cells might play a role in the pathogenesis of infertility in women with persistent chlamydial infection [Hsp10]. (Mus musculus) PubMed
7602.
IgA1 protease might contribute to S. suis pathogenesis. (Mus musculus) PubMed
7603.
The immediate early gene 2 is duplicated in the genome of bovine herpesvirus 4 isolate U. [IE2] (Mus musculus) PubMed
7604.
The authors demonstrate a role of GCS3 in plasminogen-dependent streptococcal adherence to human pharyngeal cells (cell line Detroit 562) that indicates an additional function of the protein as an adhesin in the oral cavity.[GCS3] (Mus musculus) PubMed
7605.
Cbk1-mediated phosphorylation of Ssd1 promotes the cortical localization of Ssd1-mRNA complexes. [CBK1] (Mus musculus) PubMed
The aim of this study was to develop molecular markers for Sr13 facilitating efficient pyramiding of Sr genes.[Sr13] (Mus musculus) PubMed
7608.
The recombination between leaf rust resistance gene Lr53 and stripe rust resistance gene Yr35, to identify simple sequence repeats markers linked to these genes, and to determine linkage relationships between Lr53 and Lr36.[Lr35, Yr35, Lr36] (Mus musculus) PubMed
7609.
(IE-1) Human cytomegalovirus major immediate early protein (IE)1 of 72 kDa associates with metaphase chromatin, recruiting both tumor suppressor protein IE1-of 72kDa, recruiting both promyelocytic protein (PML) and STAT2. (Mus musculus) PubMed
7610.
SspA of S. suis shared similarities with subtilisin-like proteases produced by other pathogenic streptococci and may contribute to the pathogenic process of S. suis infections. [SspA] (Mus musculus) PubMed
7611.
Sequence analysis of full-length endoglucanase 1 (TcEG1) cDNA clone shows sequence homology to glycosyl hydrolase family 9 (GHF9) enzymes & verified presence of a change (Gly for Ser) in the conserved catalytic domain for GHF9 cellulases. [TcEG1] (Mus musculus) PubMed
7612.
results suggest that OsRad21-2 functions in regulation of cell division and growth[Rad21-2] (Mus musculus) PubMed
7613.
These results demonstrate that Pac1 negatively regulates Tri gene expression and toxin production in Fusarium graminearum.[Pac1 & Tri] (Mus musculus) PubMed
7614.
These results strongly support a model in which HU binds to and stabilizes the stacked-X DNA conformation. [HU] (Mus musculus) PubMed
7615.
Tem1 is required at the spindle pole bodies for the proper function of the mitotic exit network and spindle position checkpoint. (Mus musculus) PubMed
7616.
[NS-5A] An amphipathic alpha-helical peptide [C5A] of hepatitis C virus derived from its nonstructural 5A membrane anchor domain is a chemoattractant and activator of phagocytic leukocytes via the host formyl peptide receptor. (Mus musculus) PubMed
7617.
A repression of phloem feeding was induced by HrpNEa in wild-type (WT) Arabidopsis but not in atpp2-a1/E/142, the plant mutant that had a defect in the AtPP2-A1 gene, the most HrpNEa-responsive of 30 AtPP2 genes.[HrpNEa] (Mus musculus) PubMed
7618.
These results allowed the conclusion that TolC plays an important role as a virulence and fitness factor of Erwinia amylovora by mediating resistance towards phytoalexins through its exclusive interaction with AcrAB.[TolC] (Mus musculus) PubMed
7619.
EpsL may function as a scaffold to link EpsG and EpsE and thereby transduce the energy generated by ATP hydrolysis to support secretion. [EpsL, EpsG] (Mus musculus) PubMed
7620.
The binding of 14-3-3 proteins to Yak1 coincides with PKA activity and such regulatory mechanisms might allow cytoplasmic retention of an inactive form of Yak1 under high glucose conditions.[Yak1, PKA, Bmh1] (Mus musculus) PubMed
7621.
Full kinase activation involves interaction of CheA with groups of three receptor dimers, presumably as a trimer of dimers, and that more extensive interactions among receptors are not necessary for full kinase activation.[CheA] (Mus musculus) PubMed
7622.
DksA2 plays a role in Zn homeostasis and serves as a back-up copy of the canonical Zn-dependent DksA in Zn-poor environments.[DksA] (Mus musculus) PubMed
7623.
MrpA is a new site-specific tyrosine recombinase that acts with mrpS. [MrpA] (Mus musculus) PubMed
7624.
Using this HSF1 CE2 deletion mutant the authors demonstrate that Hsf1 activation, and hence thermal adaptation, contributes significantly to the virulence of Candida albicans.[Hsf1] (Mus musculus) PubMed
7625.
Two COL17A1 orthologues were identified in the zebrafish genome, col17a1a and col17a1b, which are expressed in the skin and the neural system, respectively. (col17a1a and col17a1b) (Mus musculus) PubMed
7626.
EPG-8 may function as a highly divergent homolog of the yeast autophagy gene Atg14. (Mus musculus) PubMed
7627.
results indicate that a discrete surface of the urease UreA-UreB complex is important for Helicobacter pylori strain X47 persistence during gastric colonisation [UreA & UreB] (Mus musculus) PubMed
7628.
Data show that in the G3 strain of An. gambiae AgApoLp-III participates in midgut epithelial defense responses that limit Plasmodium infection: [ApoLp-III] (Mus musculus) PubMed
7629.
Data show that CovR directly binds to the putative promoter region of SMU.1882 [SMU.1882] (Mus musculus) PubMed
7630.
These studies demonstrate that Cryptococcus neoformans CRK1 gene functions as a negative regulator in the mating differentiation.[CRK1] (Mus musculus) PubMed
7631.
Wheat head infection by the disruptants was severely attenuated, indicating the involvement of FgATG15 in pathogenesis.[ATG15] (Mus musculus) PubMed
7632.
The decrease in Noa1 expression level resulted in a decrease in NO production in roots, but not in symbiotic nodules. [Noa1] (Mus musculus) PubMed
7633.
study showed that P-TEFb and Dengue virus (DENV) core protein work in concert to enhance IL-8 gene expression by DENV infection [core protein] (Mus musculus) PubMed
7634.
Pirenzepine may affect Smad3 signaling pathway and CTGF in the sclera by inhibiting the development of form deprivation myopia. [Smad3; CTGF] (Mus musculus) PubMed
7635.
TaSnRK2.7 is involved in carbohydrate metabolism, decreasing osmotic potential, enhancing photosystem II activity, and promoting root growth. [SnRK2.7] (Mus musculus) PubMed
7636.
CBL4 is the barley homologue of the Arabidopsis SOS3 controlling the Na+ transport. [CBL4] (Mus musculus) PubMed
7637.
The results indicate that during glycerol fermentation, H+ was expelled via F1F0. [F1F0] (Mus musculus) PubMed
7638.
MDR2 is proposed to modulate antifolate responses, possibly mediated by the transport of folate intermediates.[MDR2] (Mus musculus) PubMed
7639.
miRNA-488 is one of regulator in cell to ECM (extracellular matrix) interaction through modulation of focal adhesion activity by MMP-2 during chondrogenesis of limb mesenchymal cells. (Mus musculus) PubMed
7640.
The authors showed that substitutions of neuraminidase (NA) residues 234, 241, 257, 286 and 345, adversely affected the NA-mediated viral particle release, suggesting that these residues are critical for NA enzymatic activity.[NA] (Mus musculus) PubMed
7641.
A heparin binding site motif in members of the Duffy binding protein family may form part of a conserved erythrocyte receptor binding pocket. (Mus musculus) PubMed
7642.
HTLV-1 p30 interacts with ATM and REGgamma to increase viral spread by facilitating cell survival (Mus musculus) PubMed
7643.
Analysis of 656 full-length sequences from 13 parasite populations in Africa, Asia, Oceania, and South America revealed 64 single nucleotide polymorphisms (SNPs), of which 43 were newly identified and 38 resulted in amino acid substitutions [PfATP6] (Mus musculus) PubMed
7644.
we report identification and characterization of a novel 62-amino acid peptide, designated as hemolymph major anionic peptide (HemaP), from the hemolymph of Bombyx mori larvae that induces foraging behaviors[HEMAP] (Mus musculus) PubMed
7645.
SdrE has been previously proposed to play role in bone infections, whilst our results can indicate that sdrD plays a role in the interactions between the pathogen and human human blood.[sdrD & sdrE] (Mus musculus) PubMed
7646.
A novel galanin type I-like receptor is characterized. (Mus musculus) PubMed
7647.
Results show that the RNA toxicity induced by expanded CAG and CUG repeats can be mediated, at least in part, through the functional alteration of muscleblind protein in Caenorhabditis elegans [muscleblind]. (Mus musculus) PubMed
7648.
ADT-2 is required for normal levels of expression of a DBL-1-responsive transcriptional reporter.[ADT-2, DBL-1] (Mus musculus) PubMed
7649.
It is proposed that serine phosphorylation of hepatitis C virus E2 gene has a significant role in interferon resistance.[E2] (Mus musculus) PubMed
7650.
The F103L and M106I NS1 mutations were adaptive genetic determinants of growth and virulence in both human and avian NS1 genes in the mouse model.[NS1] (Mus musculus) PubMed
7651.
The authors found that the envelope proteins of genotype 1 were fully functional in genotype 2 porcine reproductive and respiratory syndrome virus, and the chimeric progeny viruses showed robust genetic stability and replication properties in vitro. (Mus musculus) PubMed
7652.
Two cDNA clones coding for alpha-type carbonic anhydrases (CA; EC 4.2.1.1) in the nitrogen-fixing nodules of the model legume Lotus japonicus were identified.LjCAA1, LjCAA2] (Mus musculus) PubMed
7653.
Zcf37 acts as an activator of white cell formation and a repressor of opaque state and functions upstream of Efg1.[Zcf37] (Mus musculus) PubMed
7654.
The authors now report that the influenza C virus NS1 protein also inhibits the RIG-I-mediated IFN signalling.[NS1] (Mus musculus) PubMed
7655.
LdCSBP Smr domain independently possesses both DNA and RNA endonuclease activities, but the full-length LdCSBP exhibits only riboendonuclease activity.[LdCSBP] (Mus musculus) PubMed
7656.
sequenced the Pv200L coding region of MSP-1; found two new alleles and several previously unidentified dimorphic substitutions and significant size polymorphism [MSP-1] (Mus musculus) PubMed
7657.
full-length sequences of msp1p gene were generally highly conserved; they had a few amino acid substitutions, 1 highly polymorphic E/Q-rich region and a single-to-triple hepta-peptide repeat motif; 21 allelic types of E/Q-rich region identified [msp1p] (Mus musculus) PubMed
7658.
The MtCRE1-dependent cytokinin pathway is required to regulate Nod factor signaling genes. [CRE1] (Mus musculus) PubMed
7659.
GcpA is critical for cellulose production and biofilm formation on polystyrene surface. [GcpA] (Mus musculus) PubMed
7660.
Alanine-substitution within Core regions I, II, III and IV of classical swine fever virus identified residues that specifically mediate the Core-IQGAP1 interaction.[Core] (Mus musculus) PubMed
7661.
The authors conclude that dengue virus type-1 M protein does not show pH-activated ion channel activity.[M] (Mus musculus) PubMed
7662.
P. patens encodes BOP-like genes that are post-transcriptionally regulated by Pp-miR534. Deletion of PpMIR534a causes elevated PpBOP1/2 transcript levels and early formation of gametophores. [miR534] (Mus musculus) PubMed
7663.
Pep was a luxO-regulated extracellular protein and involved in the motility. [Pep, luxo] (Mus musculus) PubMed
7664.
The four loci of DLK1 gene and CLPG gene in 1109 individuals, which belong to eight breeds/species of bovidae, including cattle, buffalo and yak, were analyzed. (Mus musculus) PubMed
7665.
Bidirectional motor learning, like bidirectional synaptic plasticity, requires the activation of mGluR1 in the cerebellar cortex. Without mGluR1 activity, learning becomes unidirectional. mGluR1. (Mus musculus) PubMed
7666.
The study determined that the mismatch repair initiation protein MutS forms a transient clamp that scans duplex DNA for mismatched nucleotides by 1D diffusion for 1 s (~700 base pairs) while in continuous rotational contact with the DNA. [MutS] (Mus musculus) PubMed
7667.
Coupling SlmA activation to specific DNA binding provides a mechanism for the precise spatiotemporal control of its anti-FtsZ activity within the cell.[SlmA, FtsZ] (Mus musculus) PubMed
7668.
It was found that homotropic allostery between the two active sites of the homodimeric enzyme is modulated by opposing mechanisms. [aminoglycoside N-(6')-acetyltransferase-Ii] (Mus musculus) PubMed
7669.
The study reports the crystal structures of Kluyveromyces lactis Xrn1 (residues 1-1,245, E178Q mutant), alone and in complex with a Mn(2+) ion in the active site. [Xrn1] (Mus musculus) PubMed
7670.
Down-regulation of Hel61 [renamed REH1 (RNA editing helicase 1)] expression in Trypanosoma brucei selectively affects editing mediated by two or more overlapping guide RNAs.[REH1] (Mus musculus) PubMed
7671.
The study shows that the structure of FliJ derived from Salmonella enterica serovar Typhimurium is remarkably similar to that of the two-stranded alpha-helical coiled-coil part of the gamma subunit of F(o)F(1)-ATP synthase. [FliJ] (Mus musculus) PubMed
7672.
we identified CD4, CD8alpha and CD8beta gene homologs both in Xenopus tropicalis, whose full genome has been sequenced, and its sister species Xenopus laevis [CD4, CD8 alpha and beta] (Mus musculus) PubMed
7673.
Data show that CtkA from H. pylori J99 is a unique eukaryotic-type Ser/Thr kinase that translocates into human cells to up-regulate the NF-kappaB activity in a kinase-dependent manner [CtkA/JHP940]. (Mus musculus) PubMed
7674.
Results describe the NMR structure of insulin receptor tyrosine kinase substrate (IRTKS) SH3 domain in complex with a repeat from Escherichia coli-secreted protein F-like protein encoded on prophage U [EspF(U)] (Mus musculus) PubMed
7675.
The ion concentration-dependent changes in the thermal stability of the protein, evaluated as the Tm value for thermal-induced denaturation of the protein, may suggest the existence of both high- and low-affinity K+ binding sites of KcsA. (Mus musculus) PubMed
7676.
SAM enzymes identified that methylate C atoms not inherently nucleophilic via intermediacy of 5'-deoxyadenosyl 5'-radical; determined reaction mechanism targeting sp(2)-hybridized carbons at position 2 and 8 of adenosine in 23S RRNA catalyzed by Cfr [Cfr] (Mus musculus) PubMed
7677.
Affected lambs were found to be deficient in glucocerebrosidase activity, and mutational analysis found them to be homozygous for the missense mutations c.1142G>A (p.C381Y) and c.1400C>T (p.P467L).[beta glucocerebrosidase, sheep]. (Mus musculus) PubMed
7678.
Respiratory infection of mice with an N1L deletion mutant virus (ECTVDeltaN1L) demonstrated profound attenuation of the mutant virus, confirming N1 as an orthopoxvirus virulence factor. (Mus musculus) PubMed
7679.
OsHAK5 functions as a Na+-insensitive K+ transporter, while OsHAK2 is sensitive to extracellular Na+ and exhibits higher Na+ over K+ transport activities. [HAK2; HAK5] (Mus musculus) PubMed
7680.
dynein controls kinesin-3 activity on the early endosomes and thereby determines the long-range motility behavior of the organelles.[Dynein heavy chain] (Mus musculus) PubMed
7681.
crystal structure of the FGL1 gene product, an extracellular lipase of gibberella zeae (GZEL) (Mus musculus) PubMed
7682.
the role of the FAD moiety conformation and the structural determinants involved in stabilizing it, ultimately modulating the functional output of ferredoxin-NADP(H) reductases [FNR] (Mus musculus) PubMed
7683.
high-resolution structure of the extracellular region of PrkC: reveals typical features of adhesive proteins [PrkC, protein kinase C (a serine/threonine kinase)] (Mus musculus) PubMed
Mutations in the polymerase proteins PB1 and PB2 played a crucial role in the temperature sensitive growth phenotype of cold-adapted A/Leningrad/134/17/57 (H2N2) virus.[PB1 & PB2] (Mus musculus) PubMed
7686.
Collectively, these results demonstrate that foot-and-mouth disease virus Lb(pro) possesses deubiquitinase activity in addition to serving as a viral proteinase.[Lb(pro)] (Mus musculus) PubMed
7687.
Overexpression of acrA and acrB overexpression storngly correlated with fluoroquinolone and multidrug resistance. [acrA,acrB] (Mus musculus) PubMed
7688.
Azole susceptibility, ergosterol levels, and expression of ERG genes were elevated in an A643V amino acid substitution in Upc2p transcription factor. [Upc2p] (Mus musculus) PubMed
7689.
These results indicate that key cellular functions of Ufd2 and Ufd3 in proteasomal protein degradation require their interaction with Cdc48.[Ufd2, Ufd3, Cdc48] (Mus musculus) PubMed
7690.
The binding of a phosphate ion to the Escherichia coli phosphate-binding protein, was studied.[PBP] (Mus musculus) PubMed
7691.
Cells that might otherwise recover from damage or injury are destroyed in progranulin mutants, which in turn facilitates disease progression.[PGRN-1] (Mus musculus) PubMed
7692.
pol V and pol IV compete to carry out error-prone bypass of the G[8,5-Me]T cross-link [DNA polymerase IV][DNA poymerase V] (Mus musculus) PubMed
7693.
replacement of Ile274 results in a reduction in catalytic efficiency [HPII] (Mus musculus) PubMed
7694.
This study found that state mutant versions of cohesin colocalize with Scc2/4 at core centromeres, sites that catalyze wild-type cohesin's recruitment to sequences 20 kb or more away.[cohesin; Scc2; Scc4] (Mus musculus) PubMed
7695.
Docking of eIF2alpha on PKR induces a conformational change that regulates the degree of Ser51 exposure and thus restricts phosphorylation to the proper kinases.[PKR, eIF2alpha] (Mus musculus) PubMed
7696.
Amino acids outside the core-binding region of PB1 are essential for PA binding. {PB1, PA] (Mus musculus) PubMed
7697.
Viruses expressing the hemagglutinin of pandemic influenza A viruses were associated with significant pathology in the lower respiratory tract, including acute inflammation, and showed low binding activity for lung surfactant protein D.[HA] (Mus musculus) PubMed
[OsCCC1] cloning and demonstration of a significant role in K+ and Cl- homeostasis and development (Mus musculus) PubMed
7700.
[OsIRO2] required under iron deficient conditions and role in germination and seed maturation (Mus musculus) PubMed
7701.
gene expression and DNA methylation of OsMAPK2 in the process of callus formation [MAPK2] (Mus musculus) PubMed
7702.
OsPSK3 increases chlorophyll content of leaves in rice [PSK3] (Mus musculus) PubMed
7703.
The function of 28-residue asparagine repeat present in the P. falciparum proteasome lid subunit 6, Rpn6, was analyzed.[Rpn6] (Mus musculus) PubMed
7704.
demonstrate for the first time in fish the presence of both PACAP transcriptional variants [PACAP]in spleen (Mus musculus) PubMed
7705.
data demonstrate that both mammalian and teleost FXR (Fxralpha2 isoform) are activated by primary and secondary bile acids [Fxralpha] (Mus musculus) PubMed
7706.
Increased caspase 12 expression causes endoplasmic reticulum stress-related apoptosis in cochlea cells after exposure to intense noise. (Mus musculus) PubMed
7707.
These results indicate that arginine activates the MTOR/FRAP1-ribosomal protein S6 kinase, k-90 (RPS6K)-RPS6 signaling pathway in ovine trophectoderm cells.[RPS6K] (Mus musculus) PubMed
7708.
The newly cloned ovine FcgammaRIII cDNA contains a 940 bp open-reading frame, and is predicted to encode a 250 amino acid glycoprotein composed of two extracellular domains, a transmembrane region and a short cytoplasmic tail.[FcgammaRIII] (Mus musculus) PubMed
7709.
MT1-MMP plays a crucial role in RAGE-activated NADPH oxidase-dependent signaling pathways.[RAGE] (Mus musculus) PubMed
7710.
functional interaction between RNA polymerase and RapA [RapA] (Mus musculus) PubMed
7711.
Further evidence for the specific interaction of G3 and L5 was obtained by mass spectrometry.[G3] (Mus musculus) PubMed
7712.
In addition to rcnA, RcnR controls expression of its own gene in response to Ni and Co, but the two genes are differentially expressed [RcnR][RcnA] (Mus musculus) PubMed
7713.
analysis of Pap1-dependent regulation of the Schizosaccharomyces pombe spy1 gene under nitrosative and nutritional stresses [spy1] (Mus musculus) PubMed
7714.
analysis of site-directed mutagenesis of phyI1s from Aspergillus niger (Mus musculus) PubMed
7715.
The genetics and phenotyping of CMY-2 beta-lactamase (bla CMY-2) producing Salmonella typhimurium in Japanese cattle are reported.[bla CMY-2] (Mus musculus) PubMed
7716.
analysis of cloning and enzyme structure modeling of the Aspergillus oryzae N74 fructosyltransferase [FTase] (Mus musculus) PubMed
7717.
the mechanism of ADP arsenolysis mediated by Escherichia coli PNPase [polynucleotide phosphorylase] (Mus musculus) PubMed
7718.
the structure of D-serine dehydratase [D-serine dehydratase] (Mus musculus) PubMed
7719.
crystal structure of catalytic core of methionyl-tRNA synthetase [methionyl-tRNA synthetase] (Mus musculus) PubMed
7720.
Crystal structure of curcuminoid synthase from Oryza sativa (Mus musculus) PubMed
7721.
The 972 bp length of transaldolase gene tal was cloned from Pichia stipitis CICC1960, encoding a 323 amino acid protein with a calculated molecular mass of 35.36 kDa and isoelectric point of 5.20.[Tal] (Mus musculus) PubMed
7722.
rAaTI can probably inhibit thrombin by interacting with thrombin exosite 2 [rAaTI] (Mus musculus) PubMed
7723.
Overexpression of stuA increased the transcript levels of brlA and abaA (another developmental regulator) and derepressed conidiation during liquid-submerged growth but did not affect penicillin V productivity. [StuA, BrlA (Mus musculus) PubMed
7724.
investigation of role of IE2 in up-regulation of host IL8 metabolism/secretion (bovine BoHV-4 induced endometritis cell model) [IE2; Immediate Early 2; ORF50; Rta] (Mus musculus) PubMed
7725.
ArgR can affect FarR binding to the argB promoter region, as protein binding is dominated by the protein most able to do so. [FarR] (Mus musculus) PubMed
7726.
Overexpression of MAIF1 reduces abiotic stress tolerance and promotes root growth. [MAIF1] (Mus musculus) PubMed
7727.
our results suggest that IPSE/alpha-1 from schistosome eggs may have additional nuclear functions in host cells. [IPSE] (Mus musculus) PubMed
7728.
We identified a novel effector protein in the repertoire of V. cholerae, annotated as A33_1663 and herein named VopX [VopX] (Mus musculus) PubMed
7729.
These results identify acidic patch residues of H2A.Z that are critical for mediating deposition and function in chromatin.[H2A.z] (Mus musculus) PubMed
7730.
The present article reports on the characterization of the urochordate metallothionein (MT) gene, CiMT-1, from the solitary ascidian Ciona intestinalis. [CiMT-1] (Mus musculus) PubMed
7731.
A model of the regulation of the lpfA1 operon of E. coli O157:H7 by H-NS and Ler is discussed.[H-NS; Ler; lpfA1] (Mus musculus) PubMed
7732.
This study investigated a previously uncharacterized gene, esaD, downstream of esxB.[esaD] (Mus musculus) PubMed
7733.
This study demonstrated that FsrA binds to two imperfect direct repeats separated by 13 bp, based on the consensus sequence of FsrA, T/AT/CAA/GGGAA/G, which is consistent with the binding characteristics of LytTR domains.[FsrA] (Mus musculus) PubMed
7734.
The SRS1 mRNA and proteins are abundant in wild type rice specifically in young organs, namely young leaves, internodes and panicles [SRS1] (Mus musculus) PubMed
7735.
Mid1p contributes to controlling cell cycle-specific gene expression as part of a feedback loop.[Mid1p] (Mus musculus) PubMed
7736.
Clp1p controls cell cycle-specific gene expression through binding to and dephosphorylating Mbx1p.[Clp1p] (Mus musculus) PubMed
unfolded protein response (UPR) in Pichia pastoris requires splicing of a non-conventional intron in the HAC1(u) mRNA [HAC1] (Mus musculus) PubMed
7739.
AHD of Arv1 is required for mating, pheromone-induced G1 cell cycle arrest, and for sterol trafficking [Arv1, strain w303] (Mus musculus) PubMed
7740.
Debaryomyces hansenii has two genes (DhCTA1 and DhCTT1) encoding two catalase isozymes with a differential enzymatic activity profile which is not strictly correlated with a differential expression profile of the encoding genes.[CTA1 & CTT1] (Mus musculus) PubMed
7741.
A novel LDH homologue, designated as BmLDH1, was firstly identified and characterized from the silkworm, Bombyx mori.[BmLDH1] (Mus musculus) PubMed
7742.
NMR solution structure and function of BamE within the outer membrane and the beta-barrel assembly machine. [BamE] (Mus musculus) PubMed
7743.
The MET15 gene encodes O-acetyl homoserine thiolase. Disruption leads to strict organic sulfur auxotrophy. [MET15] (Mus musculus) PubMed
7744.
Mutation of the S. epidermidis tagO gene has pleiotropic effects, including impaired biofilm production and increased autolytic activity. [TagO] (Mus musculus) PubMed
7745.
The latch, an insertion into the helicase-like domain of reverse gyrase, coordinates the individual domain activities by modulating the helicase-like domain, and by communicating changes in the nucleotide state to the topoisomerase domain(reverse gyrase). (Mus musculus) PubMed
7746.
we cloned and expressed full-length vibriolysin gene from V. cholerae [vibriolysin] (Mus musculus) PubMed
7747.
Xray structural explanation for the pathological properties of the complex formed between streptococcal M1 and human fibrinogen [M1] (Mus musculus) PubMed
7748.
ZmPep1 pretreatment was found to enhance resistance to both southern leaf blight and anthracnose stalk rot caused by Cochliobolis heterostrophus and Colletotrichum graminicola, respectively.[ZmPep1] (Mus musculus) PubMed
7749.
LRP is involved in lipoprotein endocytosis and parasite replication.[LRP] (Mus musculus) PubMed
7750.
MscL self-assembly into channel clusters plays an osmoregulatory functional role in the membrane [MscL] (Mus musculus) PubMed
7751.
These results showed that IL-1beta and IL-1 receptor types I and II (IL-1R type 1, IL-1R type II) were expressed in the ovine hypothalamus in response to lipopolysaccharide injection.[IL-1R type 1; IL-1R type 2] (Mus musculus) PubMed
7752.
Activation Induced Cytidine Deaminase (AID)-induced translocations were strongly enhanced in yeast THO null mutants, consistent with the idea that AID-mediated DSBs depend on R-loop formation[Activation Induced Cytidine Deaminase] (Mus musculus) PubMed
7753.
Results describe a model for full-length GBS80 (N1, N2, and N3) with the help of available homologous major pilin structures, and suggest a model for the GBS PI-1 pilus shaft [GBS80]. (Mus musculus) PubMed
7754.
Our results reveal a novel binding mode between the Sec1p C-terminal tail and the SNARE complex, and suggest a role for Mso1p as an effector of Sec4p (Sec1p, Mso1p) (Mus musculus) PubMed
7755.
A report on the crystal structure of NpmA and its complex with AdoMet and AdoHcy, along with structure-guided functional and modeling studies (NpmA). (Mus musculus) PubMed
7756.
a novel major transcript of the Oryzias latipes AIFL gene that retained intron 4 (AIFL-I4) in embryos and tissues from adult fish was identified. [AIFL] (Mus musculus) PubMed
7757.
propose that NhABC1 and the cytochrome P450 may function in a sequential manner in which the energy expense from pisatin efflux by NhABC1 releases the repression of the cytochrome P450, ultimately allowing pisatin tolerance by two mechanisms [ABC1] (Mus musculus) PubMed
7758.
OsCIPK10 decreases under high salt and increases in low potassium conditions. [CIPK10] (Mus musculus) PubMed
7759.
investigation of molecular conformation and Mg2+ and Na+ binding sites during catalysis [HDV ribozyme] (Mus musculus) PubMed
7760.
These results provide evidence that Osg1 is essential for timely callose degradation in the process of tetrad dissolution.[Osg1] (Mus musculus) PubMed
7761.
Rre37 is involved in induction of glycolytic and glycogen catabolic genes during nitrogen depletion. [Rre37] (Mus musculus) PubMed
7762.
The fission yeast casein kinase 1 (CK1) delta/epsilon isoforms Hhp1 and Hhp2 are required for full levels of Rec8 phosphorylation and for efficient removal of Rec8 at the onset of anaphase I.[Rec8, Hhp1, Hhp2] (Mus musculus) PubMed
7763.
We report that Glycosomal ABC transporters GAT1 and GAT3 are expressed both in bloodstream and procyclic form trypanosomes, whereas GAT2 is mainly or exclusively expressed in bloodstream-form cells. [GAT1, GAT2, GAT3] (Mus musculus) PubMed
7764.
GDF11 has a central role in the activation of Smad2 phosphorylation in tailbud stage Xenopus embryos.[GDF11] (Mus musculus) PubMed
7765.
Data show that constitutive expression of IL-IL-23 p19 was observed in the kidney, liver, gut and muscle: [IL-23 p19] (Mus musculus) PubMed
7766.
(RGEF-1b) RasGRP protein RGEF-1b couples external stimuli to behavior by activating LET-60 protein in sensory neurons. (Mus musculus) PubMed
7767.
in Xenopus ovarian follicles FP receptors play an important role during gonadotropin- and progesterone-induced ovulation [prostaglandin F2alpha receptor isoform A][prostaglandin F2alpha receptor isoform B] (Mus musculus) PubMed
7768.
Infection with a H. pylori strain containing the dupA without the stop codon polymorphisms is associated with a lower risk of development of gastric carcinoma in Brazilian subjects.[dupA] (Mus musculus) PubMed
7769.
roles of active site polar residues Glu47, Gln110, Lys159, and His251 for elementary steps of catalysis [AHAS II] (Mus musculus) PubMed
7770.
a conformational change as a result of substrate binding [YidC] (Mus musculus) PubMed
7771.
crystal structure of a representative NAT protein, the Escherichia coli uracil/H(+) symporter UraA, in complex with uracil at a resolution of 2.8 A [UraA] (Mus musculus) PubMed
7772.
The authors showed that thermal unfolding of the autochaperone region is reversible and determined its crystal structure at 2.0-A resolution.[IscA] (Mus musculus) PubMed
7773.
the in vitro incorporation of methylmalonyl groups ligated by MatB to CoA, pantetheine, or N-acetylcysteamine into a triketide pyrone by the terminal module of the 6-deoxyerythronolide B synthase [MatB] (Mus musculus) PubMed
7774.
The results of this study show that the anti-apoptotic proteins, HSP70 and alpha-BC, were overexpressed with increased apoptosis in foot-and-mouth disease virus-infected heart tissues.[HSP70] (Mus musculus) PubMed
7775.
The authors show that at least two foamy virus protease-reverse transcriptase molecules bind to the protease-activating RNA motif and only RNAs containing this motif result in significant activation of the protease.[protease] (Mus musculus) PubMed
7776.
Mutations in ArsD near the metalloid binding site and on the surface of the helix 1 affect binding with the ArsA ATPase. [ArsD] (Mus musculus) PubMed
7777.
CgYPS1 is essential for survival in the post-diauxic growth phases, and is required to survive low-pH environment. [Yps1] (Mus musculus) PubMed
7778.
STE50 is involved in multiple steps of sexual reproduction, andfunctions between Ste11p and Ste20p as an adapter protein and regulates the activation of Ste11p. [STE50] (Mus musculus) PubMed
7779.
A cleaved amplified polymorphic sequence (CAPS) marker that is associated with the presence or absence of the S2 gene was developed in 115 of 122 (95%) diverse wheat lines.[Sr2] (Mus musculus) PubMed
7780.
SAP1 is involved in a selective post-transcriptional mechanism to regulate the abundance of transcripts critical to the infectivity of sporozoites. [Sap1] (Mus musculus) PubMed
7781.
Zcf37p is the DNA binding factor that recruits Mcm1p to target promoters that directly activate adhesion genes. [Ahr1] (Mus musculus) PubMed
7782.
The authors show that the function of SsuR is essential for the utilization of a number of organic sulfur sources of either environmental or human origin.[SsuR] (Mus musculus) PubMed
7783.
CYP78As participate in the synthesis of a critical growth regulator in P. patens [CYP78A] (Mus musculus) PubMed
7784.
amphioxus Vasa and Nanos are also expressed zygotically in the tail bud[Vasa] (Mus musculus) PubMed
7785.
The potential activity of E coli GalE for free monosaccharide, was determined.[GalE] (Mus musculus) PubMed
7786.
without Chp signaling, E-cadh shifts to intracellular vesicles rather than the adhesive contacts needed for directed cell movement during epiboly. [Chp] (Mus musculus) PubMed
7787.
the single nucleotide heterogeneity (A at M847) in the Gn protein substantially affected the RVFV virulence [Gn envelope protein] (Mus musculus) PubMed
7788.
Sak189 response regulator is necessary for activation of bac gene transcription. It also controls the virulent properties of S. agalactiae [Sak189] (Mus musculus) PubMed
7789.
AcpB could provide the hydrolytic activity necessary to transform the nontransportable phosphorylated vitamin B1 present in tissues to a form that can be absorbed by the intracellular pathogen. [AcpB] (Mus musculus) PubMed
7790.
A-type inclusions phenotype is dependent on the A-type inclusion protein (Atip) and the P4c protein.[Atip & P4c] (Mus musculus) PubMed
7791.
The first type III PRMT in C. elegans, was identified. (Mus musculus) PubMed
7792.
heat tolerance function of Gts1p is regulated by Ssa1p and Ssa2p [Gts1p][Ssa1p][Ssa2p] (Mus musculus) PubMed
7793.
structural basis for recognition of budding yeast (Saccharomyces cerevisiae) CenH3 (called Cse4) by Scm3 [Scm3 & Cse4] (Mus musculus) PubMed
7794.
Protein kinase C in Neurospora crassa is activated by exogenous diacylglycerol and phorbol esters, and translocates to the plasma membrane from the cytoplasm.[protein kinase C] (Mus musculus) PubMed
An almost complete homology model of AtoC and of its putative entity as a dimer is constructed for this study, as well as a model of its binding to its target DNA sequence.[AtoC] (Mus musculus) PubMed
7797.
staphopain A (ScpA) and staphopain B (SspB)secreted from S. aureus degrade collagen and fibrinogen ledaing to clotting impariment and tissue destruction. [ScpA, SspB] (Mus musculus) PubMed
7798.
There was a predominance of one major haplotype and extreme reduction in genetic diversity of OsAMT1;1 in cultivated rice compared to that in its wild progenitor O. rufipogon. [OsAMT1;1] (Mus musculus) PubMed
A cDNA encoding a putative extracellular alpha-L-arabinofuranosidase was cloned from the basidiomycete Coprinopsis cinerea [CcAbf62A] (Mus musculus) PubMed
7801.
Kip3 clusters kinetochores on the metaphase spindle by tightly regulating kinetochore microtubule lengths.[Kip3] (Mus musculus) PubMed
7802.
Binding of calmodulin to the regulatory domain induces conformational changes that release the catalytic cleft, activating the kinase and exposing an otherwise inaccessible phosphorylation site, threonine 286.[CaMKII] (Mus musculus) PubMed
7803.
The PP2A-SUR-6 promotes centriole assembly by protecting ZYG-1 and SAS-5 from degradation. (Mus musculus) PubMed
7804.
Together, these results may suggest that both PD-1 and Tim-3 are mediators of CD8(+) T cell exhaustion and latency in LAT-expressing herpes simplex virus-1 infection.[LAT] (Mus musculus) PubMed
7805.
The authors show that the function of Cauliflower mosaic virus viroplasmin in reinitiation depends on physical association with TOR, with viroplasmin-TOR binding being critical for both translation reinitiation and viral fitness.[viroplasmin] (Mus musculus) PubMed
7806.
The results show that the carboxy-terminus of Orf is involved in nucleic acid recognition and also plays an unexpected role in maintaining structural integrity.[Orf] (Mus musculus) PubMed
7807.
The types of forces important to binding via a combination of isothermal titration calorimetry (ITC) and computational docking studies that employed rice GID1 (OsGID1), were studied.[OsGID1] (Mus musculus) PubMed
7808.
TcEF-2 bound with similar affinity to the four P1/P2 ribosomal P proteins of T. cruzi but with reduced affinity to TcP0.[EF-2] (Mus musculus) PubMed
7809.
The energetic contribution to guanylate kinase substrate binding and the forces underlying ligand recognition, was investigated.[Guanylate kinase] (Mus musculus) PubMed
7810.
TLN4 is an extensively processed putative metalloproteinase secreted from micronemes. [TLN4] (Mus musculus) PubMed
7811.
A modification of Clb2, by the C-terminal addition of a Myc12 epitope, causes the loss of one specific mitotic function of Clb2.[Clb2] (Mus musculus) PubMed
7812.
Data suggest a genetic link between AgSAC6 and AgWAL1 based on the common mutant phenotypes regarding aberrant hyphal growth and endocytosis. [WAL1] (Mus musculus) PubMed
7813.
These data suggest that the defects in sexual reproduction were caused by the reduction in histone acetylation in the ATP citrate lyase deletion mutants.[ATP citrate lyase] (Mus musculus) PubMed
7814.
DeltaMoplc2 and DeltaMoplc3 mutants developed multiple appressoria on separate germ tubes of a conidium, indicating that MoPLC2- and MoPLC3-regulated signaling suppresses a feedback loop of a pathway for appressorial development.[plc2 &plc3] (Mus musculus) PubMed
7815.
The authors propose that in the presence of chitin disaccharide, TfoR sRNA is expressed to activate the translation of tfoX, which leads to the induction of natural competence.[tfoX] (Mus musculus) PubMed
7816.
Data show that histidine decarboxylase (hdcA)was isolated from a new strain Staphylococcus epidermidis TYH1: [hdcA] (Mus musculus) PubMed
7817.
proteasomal degradation of Sfp1 is mediated by Blm10 and contributes to the repression of ribosome biogenesis under nutrient depletion.[Sfp1, Blm10] (Mus musculus) PubMed
7818.
Membrane trafficking and septins function synergistically to maintain the dynamic polarization of Cdc42p during asymmetric growth in yeast.[Cdc42, septin] (Mus musculus) PubMed
7819.
Accumulation of aggregated polypeptides was strongly decreased by the AAA-protease Pim1/LON.[Pim1] (Mus musculus) PubMed
7820.
BiP1, predominantly expressed in maturing rice endosperm, acts as not only a chaperone but also a stress sensor protein for ER quality control. (Mus musculus) PubMed
7821.
The kinetic parameters of carbohydrate oxidation catalyzed by Escherichia coli PQQ-dependent aldose sugar dehydrogenase (ASDH) were determined using various electron acceptors.[ASDH] (Mus musculus) PubMed
7822.
These results show that ERG20 (farnesyl pyrophosphate synthase) is not required for survival in an infected mouse, but the RAM2-encoded prenyltransferase was critical for growth under both in vitro and in vivo conditions.[RAM2] (Mus musculus) PubMed
7823.
PkaC2 acts in concert with PkaC1 to support cell wall homeostasis and regulate conidial germination and carbohydrate metabolism, but has limited influence on asexual development (Mus musculus) PubMed
7824.
C. albicans smt3/smt3 cells displayed defects in growth, morphology, cell separation, nuclear segregation, and chitin deposition, suggesting important roles for sumoylation in cell cycle control.[Smt3] (Mus musculus) PubMed
7825.
These data suggest that the blue-light receptor MGWC-1 in Magnaporthe oryzae is involved in light-dependent disease suppression during the dark-phase (disease-conducive light condition) immediately after pathogen-host contact.[MGWC-1] (Mus musculus) PubMed
7826.
Direct kinetic measurements of RNA polymerase II (Pol II) movement across the 9.5-kb GAL10p-VPS13 gene revealed that the elongation rate of polymerase is 24% slower in the absence of Htz1. We provide evidence for two nonexclusive mechanisms. [Htz1] (Mus musculus) PubMed
7827.
Study results establish elongator protein 3b (ELP3b) as a major negative regulator of rDNA transcription and extend the roles of the Elp3-related proteins to RNAP-I transcription units.[Elongator protein 3b] (Mus musculus) PubMed
7828.
ProQ does not regulate proP transcription. It may act as an RNA-binding protein to regulate proP translation. [ProQ][ProP] (Mus musculus) PubMed
7829.
a novel role for the identity of A-Site bound tRNA in RelA-mediated (p)ppGpp synthesis [RelA] (Mus musculus) PubMed
7830.
Expression of ClpB regulated by CtsR, appears to play a major role in induced thermotolerance and in pathogenesis, as assessed by using the Galleria mellonella virulence model. [clpB, CtsR] (Mus musculus) PubMed
7831.
janosiThese data confirm the importance of a cation-binding site in BetP, playing a key role in a proposed molecular mechanism of Na(+) and H(+) coupling in betaine-choline-carnitine transporters.[BetP] (Mus musculus) PubMed
7832.
Diclofenac inhibits respiration by interfering with Rip1p and Cox9p in the respiratory chain, resulting in ROS production that causes cell death. [Rip1, Cox9] (Mus musculus) PubMed
7833.
findings explain how Gle1(InsP6), Nup159 and Dbp5 collaborate in mRNA export and provide a general mechanism for DEAD-box ATPase regulation by Gle1/eIF4G-like activators [Gle1 & Nup159 & Dbp5] (Mus musculus) PubMed
7834.
The Ire1-catalyzed phosphoryl-transfer aids disassembly of Ire1 signaling complexes and is a critical component of the unfolded protein response homeostatic feedback loop.(Ire1) (Mus musculus) PubMed
7835.
The importance of proper Ire1 RNase attenuation is demonstrated by the inability of cells expressing Ire1-D828A to grow under ER stress. (Ire1 RNase ) (Mus musculus) PubMed
7836.
These data and the corresponding results point to one of Hfq functional structural consequences due to ATP binding and Tyr25Ala mutation.[Hfq] (Mus musculus) PubMed
7837.
The proteomic data from this study provides direct evidence that the E. coli specific beta-methylthiolation likely occurs when S12 is assembled as part of a ribosomal subunit.[Ribosomal protein S12] (Mus musculus) PubMed
7838.
Sskp, which encodes a periplasmic chaperone involved in targeting misfolded outer-membrane proteins to the beta-barrel assembly machinery, is required for infections in a murine model of typhoid. [Skp] (Mus musculus) PubMed
7839.
Hydrodynamic parameters of the holoenzyme indicated that Y. lipolytica cAMP-dependent protein kinase is a dimer of 90 kDa composed of an R subunit of 42 kDa and a C subunit of 39 kDa. [cAMP-dependent protein kinase] (Mus musculus) PubMed
7840.
Our results show that Clp dependent proteolysis of LexA is conserved in S. aureus and that the NTD may differentially regulate a subset of genes in the SOS regulon. [Clp, LexA] (Mus musculus) PubMed
7841.
These results show that the Aspergillus niger albA polyketide synthase is responsible for both the production of the spore pigment precursor and a family of naphtho-gamma-pyrones.[albA] (Mus musculus) PubMed
7842.
This protein is homologous to PfRON2 which has previously been shown to be associated with PfAMA-1, suggesting a similar role for PvRON2.[PvRON2] (Mus musculus) PubMed
7843.
Prothoracicotropic hormone (PTTH) transcripts exhibit a daily cycling profile in final larval instar. In adult females expression was initially at a nearly constant level in diapausers but decreased quickly in nondiapausers. [prothoracicotropic hormone] (Mus musculus) PubMed
7844.
study shows how yihU-yshA gene cluster forms a transcriptional unit regulated y by cAMP receptor protein; results show 2 CRP-binding sites on regulatory region of the yihU-yshA operon are required to promote transcriptional activation [CRP, yihU, yshA] (Mus musculus) PubMed
7845.
FimD-FimC-FimH structure provides unique insights into the pilus subunit incorporation cycle, and captures the first view of a protein transporter in the act of secreting its cognate substrate (Mus musculus) PubMed
7846.
NLP is also involved in repression of transcription in the inactive variant surface glycoprotein Basic Copy arrays, minichromosomes and procyclin loci (NLP). (Mus musculus) PubMed
7847.
These results suggest that Crg2 is critical for establishment of early pulmonary infection and for persistence of infection.[Crg2] (Mus musculus) PubMed
7848.
CiCAP is expressed by Ciona intestinalis hemocytes after lipopolysaccharide challenge. The polypeptide displays a modular structure with similarities to vertebrate CAP-superfamily proteins and to a collagen binding adhesin of Streptococcus mutans. [CiCAP] (Mus musculus) PubMed
7849.
central conserved domain of Prp8 is related to the catalytic domain of reverse transcriptases [Prp8] (Mus musculus) PubMed
7850.
crystal structures of ISW1a lacking its ATPase domain both alone and with DNA bound at resolutions of 3.25 A and 3.60 A, respectively; visualization of two different nucleosome-containing remodelling complexes using cryo-electron microscopy [ISW1a] (Mus musculus) PubMed
7851.
Axs5 is a GH62 alpha-L-arabinofuranosidase specific for arabinoxylan. [Axs5] (Mus musculus) PubMed
7852.
Structural asymmetry in a trimeric Na+/betaine symporter, BetP, from Corynebacterium glutamicum (BetP) (Mus musculus) PubMed
7853.
Identification of N-terminal regions of wheat leaf ferredoxin NADP+ oxidoreductase important for interactions with ferredoxin (Mus musculus) PubMed
7854.
a new 5' exon (exon 1) in the apn1 gene and show that the inactivity of S. pombe Apn1 is due to a nonsense mutation in the fifth codon of this new exon (Mus musculus) PubMed
7855.
demonstrate that in vitro Stm1 inhibits translation after formation of an 80S complex[Stm1] (Mus musculus) PubMed
7856.
The authors show that Cse3 type CRISPR-specific endoRNases bind a hairpin structure and residues downstream of the cleavage site within the repetitive segment of cognate CRISPR RNA.[Cse3] (Mus musculus) PubMed
7857.
The surface-associated subtilisin-like protease SspA induced the secretion of IL-1beta, TNF-alpha, IL-6, CXCL8 and CCL5 by macrophages. [SspA] (Mus musculus) PubMed
7858.
This study reveals the possible initial structural event that leads to release of the B loop from its prefusion conformation, which is aided by unexpected structural changes within the membrane-distal HA1 domain at low pH.[HA] (Mus musculus) PubMed
7859.
These results demonstrate the considerable pathogenicity of NA N294S substitution-possessing H5N1 viruses and underscore the importance of monitoring the emergence of the NA N294S mutation in circulating H5N1 viruses.[NA] (Mus musculus) PubMed
7860.
In addition to salt stress, the cyclophilin OsCYP2 can respond to other types of stresses, such as drought, heat and cold. [CYP2] (Mus musculus) PubMed
7861.
high resolution crystal structure of SNAC1 (stress-responsive NAC) NAC domain [SNAC1] (Mus musculus) PubMed
7862.
The N-terminal unstructured domain of yeast ODC functions as a transplantable and replaceable ubiquitin-independent degron (Mus musculus) PubMed
7863.
Q-motif not only senses the nucleotide state of the helicase but could also stabilize a catalytically competent conformation of the P-loop and other helicase signature motifs [Hera] (Mus musculus) PubMed
7864.
show that MRB3010 is essential for growth of both procyclic form and bloodstream form life-cycle stages of Trypanosoma brucei[MRB3010] (Mus musculus) PubMed
7865.
This study showed that extracellular hemicentin-1[Hmcn1] assemble at the cleavage furrow of dividing cells in the C. elegans germline and in preimplantation mouse embryos.[Hmcn1] (Mus musculus) PubMed
7866.
Dia1 mRNA localizes to the perinuclear endoplasmic reticulum through interactions between Dia1 nascent peptide and Rho-GTP. [Dia1] (Mus musculus) PubMed
7867.
Characterization of a novel Salmonella Typhimurium chitinase which hydrolyzes chitin, chitooligosaccharides and an N-acetyllactosamine conjugate (Mus musculus) PubMed
7868.
SpnA is a novel group A streptococcal virulence factor. [SpnA] (Mus musculus) PubMed
7869.
A high-affinity adenosine kinase from Anopheles gambiae. (Mus musculus) PubMed
7870.
Substitution of the highly conserved catalytic Thr132 into Ser or Ala of NPP completely abolished enzyme activity. [NPP] (Mus musculus) PubMed
7871.
CD8 T cell responses to T. annula...were shown to be focused entirely on a single dominant epitope in one antigen, Ta9. (Mus musculus) PubMed
7872.
The authors conclude that the HA-33/HA-17 arm is not necessarily required for, but facilitates, transport of botulinum toxin complexes.[HA-33 & HA-17] (Mus musculus) PubMed
7873.
These show that the mean absorbance values for binding to the HCMV UL118/UL119-encoded FcgammaR were higher for IgG1 expressing the GM 3 allotype than for those expressing the allelic GM 1,2,17 determinants (p = 0.0005).[UL118, UL119] (Mus musculus) PubMed
7874.
the possible roles of the budding yeast Smc5/6 complex in maintaining appropriate chromosome end-structures allowing cell survival in absence of telomerase[Smc5][Smc6] (Mus musculus) PubMed
7875.
The effect of the ret1-1 mutation on the secretome, the glycosylation patterns and locations of the secretory proteins, were studied.[Ret1-1] (Mus musculus) PubMed
7876.
IFE-1 is required for efficient expression of some sperm-specific proteins.[IFE-1] (Mus musculus) PubMed
7877.
studies establish XalphaCP2 as a novel cytoplasmic polyadenylation trans factor, indicate that C-rich sequences can function as noncanonical cytoplasmic polyadenylation elements[alphaCP2] (Mus musculus) PubMed
7878.
The V. cholerae CqsA/CqsS system is less stringent and does not discriminate well between ligands.[CqsA/CqsS] (Mus musculus) PubMed
7879.
The authors identify a novel Lymantria dispar multicapsid nucleopolyhedrovirus apoptosis suppressor gene, apsup, which functions to suppress apoptosis induced in Ld652Y cells.[apsup] (Mus musculus) PubMed
7880.
The authors demonstrated that the NS1 protein interacts specifically with NP and not the polymerase subunits.[NS1 & NP] (Mus musculus) PubMed
7881.
In a trans-complementation experiment with a movement-defective tomato mosaic virus, pC6 of rice grassy stunt virus facilitated intercellular transport of the virus.[pC6] (Mus musculus) PubMed
7882.
These results provide support for a role for the extreme amino terminus of NS3 in the late stages of virus growth in mammalian cells, plausibly in egress.[NS3] (Mus musculus) PubMed
7883.
The authors show that the mouse cytomegalovirus m155 open reading frame is required for the posttranscriptional inhibition of CD40 expression in infected antigen-presenting cells. (Mus musculus) PubMed
7884.
V. harveyi CqsA/CqsS system is exquisitely selective for (Z)-3-aminoundec-2-en-4-one. [CqsA,CqsS] (Mus musculus) PubMed
7885.
CaBP1 regulates voltage-dependent inactivation and activation of Ca(V)1.2 (L-type) calcium channels [CaBP1] (Mus musculus) PubMed
7886.
characterization of a hyperthermostable Mn-superoxide dismutase from Thermus thermophilus HB27 (Mus musculus) PubMed
7887.
crystallization and preliminary X-ray analysis of SaMazF; crystals of S. aureus MazF (SaMazF) were grown in space group P2(1)2(1)2(1);crystals diffracted to 2.1A resolution and are likely to contain two SaMazF dimers in the asymmetric unit [MazF] (Mus musculus) PubMed
7888.
The Ndc80 loop region has an important role in the conversion from lateral to end-on attachment, a crucial maturation step of kinetochore-microtubule interaction. (Mus musculus) PubMed
7889.
analysis of the mechanism of action of TbREL1 inhibitors [TbREL1] (Mus musculus) PubMed
7890.
ATF3 interacts with HTLV-I bZIP factor and promotes proliferation of ATL cells. (Mus musculus) PubMed
7891.
It is demonstrated that the inter-subspecific differentiation of SD1 contributes height difference between indica and japonica [SD-1] (Mus musculus) PubMed
7892.
characterization of the Streptococcus pneumoniae RrgB pilus backbone D1 domain [RrgB] (Mus musculus) PubMed
7893.
Integral membrane cargo proteins become polarized by directed vesicle traffic given the experimentally determined rates of vesicle traffic and diffusion but cannot effectively polarize the more rapidly diffusing Cdc42p. (Mus musculus) PubMed
7894.
PSS1 is a novel member of the kinesin-1 family essential for male meiotic chromosomal dynamics, male gametogenesis, and anther dehiscence in rice. (Mus musculus) PubMed
7895.
PDIL1;1 localizes to the ER lumen and facilitates the oxidative folding of vacuole-targeted storage proteins. PDIL2;3 localizes on the protein body surface and promotes the specific localization of crP10 in the protein body core. [PDIL1;1 & PDIL2;3] (Mus musculus) PubMed
7896.
SUB1A confers drought tolerance to rice, increases ABA responsiveness, and enhances oxidative stress tolerance. (Mus musculus) PubMed
7897.
expression of Paracoccidioides brasiliensis alternative oxidase is developmentally regulated through mycelium to yeast differentiation. [AOX] (Mus musculus) PubMed
7898.
M-Enk expression after complete dorsal rhizotomy is mainly on the lateral side in lamina II of the sprinal cord. [M-Enk] (Mus musculus) PubMed
7899.
Dendroaspis natriuretic peptide was detected in heart, kidney, liver, brain, and plasma of New Zealand rabbits. It may help to maintain sodium and fluid volume homeostasis in a healthy cardio-renal environment. (Mus musculus) PubMed
7900.
Vaccinia virus VH1 is essential for dephosphorylation of STAT1 at tyrosine 701 [VH1] (Mus musculus) PubMed
7901.
OmpD, the most abundant porin in Salmonella enterica serovar Typhimurium, facilitates uptake of hydrogen peroxide (HO) and that its expression is negatively regulated by ArcA upon peroxide exposure. [OmpD] (Mus musculus) PubMed
7902.
Candida glabrata Pdr1 combines features of Saccharomyces cerevisae Pdr1 and Pdr3 to produce a transcription factor with chimeric regulatory properties. [CgPdr1] (Mus musculus) PubMed
7903.
Hap43 executes its function by becoming a transcriptional repressor and accumulating in the nucleus in response to iron deprivation. [Hap43] (Mus musculus) PubMed
7904.
the EndoG homologue, NucA, is not involved in cell death, but it plays a role in the DNA-damaging response in Aspergillus nidulans. [nucA] (Mus musculus) PubMed
7905.
MLC2 is associated with myosin D via its calmodulin (CaM)-like domain and anchored to the plasma membrane of T. gondii via its N-terminal extension [MyoD, MLC2] (Mus musculus) PubMed
7906.
JNK expression was elevated in cochlea after exposure to intense noise. (Mus musculus) PubMed
7907.
miR-92 is a critical regulator of endoderm formation and left-right asymmetry during early zebrafish development.[miR-92 microRNA] (Mus musculus) PubMed
7908.
These studies support a role for AgAQP1 in water homeostasis during blood feeding and humidity adaptation of A. gambiae, a major mosquito vector of human malaria in sub-Saharan Africa. (Mus musculus) PubMed
7909.
ATP binding to hemoglobin response gene 1 protein is necessary for regulation of the mating type locus in Candida albicans [Hbr1] (Mus musculus) PubMed
7910.
A galactose-stable deletion derivative of Mig2 caused a strong Mig phenotype, confirming that galactose induction of the GAL1 gene requires the degradation of the repressor Mig2.[GAL1; Mig2] (Mus musculus) PubMed
7911.
Genetic analysis of the cyp-35B1 promoter showed both DAF-16 and HSF-1 are direct regulators.[HSF-1, cuyp-35B1] (Mus musculus) PubMed
7912.
The interaction between HrpB2, a small protein secreted by the Xanthomonas citri subsp. citri type III secretion system, and the cytosolic domain of the inner membrane protein HrcU, is characterized.[HrpB2, HrcU] (Mus musculus) PubMed
7913.
An evaluation of two independent domains in the monomeric protein NusG is reported.[NusG] (Mus musculus) PubMed
7914.
The single-particle cryo-EM structure of the Sec YEG complex in a membrane environment is determined. [SecY, SecE, and SecG] (Mus musculus) PubMed
7915.
Multiple regions of Bud3p ensure efficient targeting of Bud3p to the bud neck in the assembly of the axial landmark and distinct domains of Bud3p are involved in axial bud-site selection and other cellular processes.[Bud3] (Mus musculus) PubMed
7916.
Pba1-Pba2 requires a previously overlooked C-terminal hydrophobic-tyrosine-X (HbYX) motif for function. [Pba1 & Pba2] (Mus musculus) PubMed
7917.
a single point mutation (Ile219-->Lys; a base pair change) in the glycan receptor-binding site (RBS) of a representative 2009 H1N1 influenza A virus, A/California/04/09 or CA04/09, quantitatively increases its human receptor-binding affinity (Mus musculus) PubMed
7918.
The COOH-terminal truncated form of p17 (p17Delta36) induced activation of the PI3K/Akt pathway by maintaining PTEN in an inactive phosphorylated form.[p17] (Mus musculus) PubMed
7919.
These data therefore demonstrate that at least these two CgPDR1-dependent and -upregulated genes contribute to the enhanced virulence of C. glabrata that acquired azole resistance.[CgPDR1] (Mus musculus) PubMed
7920.
Motif conservation analysis revealed that nine FlbB orthologs belonging to the Eurotiales order contained a motif in the central region that could mediate interaction with FlbE.[FlbB] (Mus musculus) PubMed
7921.
the avian-like low-pH stability of sialidase activity in the 1918 pandemic virus NA contributes to the viral replication efficiency [NA, strain 1918] (Mus musculus) PubMed
7922.
Ecs is essential for staphylococcal virulence and antimicrobial resistance probably since the transport function of Ecs is essential for the normal structure and function of the cell wall [Ecs] (Mus musculus) PubMed
7923.
analysis of genomic CeMyoD binding sites revealed and cross validated by ChIP-Chip and ChIP-Seq techniques [MyoD] (Mus musculus) PubMed
7924.
TbUNC119 and its binding protein complex are essential for propagation, motility, and morphogenesis of Trypanosoma brucei procyclic form cells [TbUNC119] (Mus musculus) PubMed
7925.
SNX-6 is enriched on phagosome surfaces and promotes the fusion of early endosomes and lysosomes to phagosomes. (Mus musculus) PubMed
7926.
The N-terminal domain of Ama1p interacts with 2 motifs within Cdc20p during meiosis. [2 genes] (Mus musculus) PubMed
7927.
ewes with genotype BB had 0.58 (P < 0.01) lambs more than those with AA in Hu sheep[ inhibin beta B] (Mus musculus) PubMed
7928.
Actinobacillus pleuropneumoniae HMW1C-like glycosyltransferase mediates N-linked glycosylation of the Haemophilus influenzae HMW1 adhesin [HMW1] (Mus musculus) PubMed
7929.
findings indicate that a specific factor in royal jelly, royalactin, drives queen development through an Egfr-mediated signalling pathway [royalactin] (Mus musculus) PubMed
7930.
folding of the 790-residue membrane protein BamA, which is the core component of the Escherichia coli outer membrane protein assembly machinery [BamA] (Mus musculus) PubMed
7931.
Protein binding and unbinding of the Min proteins, MinC, MinD, and MinE functions to propagate the pole-to-pole oscillation of Min proteins involved in cell division. [3 genes] (Mus musculus) PubMed
7932.
The 1.8 A crystal structure of Cass2, an integron-associated protein derived from an environmental V. cholerae, is reported.[Cass2] (Mus musculus) PubMed
7933.
New ompA gene sequences different from L2/434 reference strain and from the L2b variant were found including point mutations at VS1 domain A294T & C472G, and VS4 C1012T. (Mus musculus) PubMed
7934.
The EndA structure reveals a DRGH (Asp-Arg-Gly-His) motif-containing betabetaalpha-metal finger catalytic core augmented by an interesting 'finger-loop' interruption of the active site alpha-helix (EndA). (Mus musculus) PubMed
7935.
The functional YFP-GmtA (GDP-mannose transporter)Golgi reporter shows the GPTase SrgC has an important role in maintaining the integrity of Golgi-like structures in A. niger. [GmtA, SrgC] (Mus musculus) PubMed
7936.
AeSCP-2 expression knockdown in early instar larvae resulted in detectable phenotypes of the expression deficiency such as high mortality, lowered fertility, and distorted sex ratio.[AeSCP-2] (Mus musculus) PubMed
7937.
Data suggest that Nato3 is a direct target of Foxa2, a transcription activator and effector of Sonic hedgehog, the hallmark regulator of neural tube floor plate induction and spinal cord development [Nato3]. (Mus musculus) PubMed
7938.
Agr and SaeRS have roles in the pathogenesis of CA-MRSA USA300 infection [SaeR, SaeS] (Mus musculus) PubMed
7939.
CDP1 and CYG56 regulation is involved in the NH4+ signalling pathway. [2 genes] (Mus musculus) PubMed
7940.
results suggest that metabotropic glutamate receptors I/II regulate the release of glutamate, likely from bipolar cells, that in turn activates GABA release from amacrine cells via a transporter mediated process[metabotropic glutamate receptor 2] (Mus musculus) PubMed
7941.
The effects of 6 mutations on CpxP function in physiological stress are reported.[CpxP] (Mus musculus) PubMed
7942.
SubAB induced small bowel hemorrhage and inflammatory changes.[SubA, subB] (Mus musculus) PubMed
7943.
dentipain contributes to the virulence of T. denticola [dentipain] (Mus musculus) PubMed
7944.
Cx50 is phosphorylated in vivo by PKA at Ser-395, which promotes increased dye permeability of Cx50 channels and plays an important role in metabolic coupling and transport in lens fibers [PKA] (Mus musculus) PubMed
7945.
These results demonstrate that during periods of hydrogen peroxide stress, the induction of YaaA is a critical device to suppress intracellular iron levels; it thereby attenuates the Fenton reaction and the DNA damage that would otherwise result.[YaaA] (Mus musculus) PubMed
7946.
analysis of how the CtrA and CtrB transporters-PCP-OPX multiprotein complex functions to export CPS across the cell envelope [CtrA, CtrB] (Mus musculus) PubMed
7947.
the kinetic mechanism for the AlkA-catalyzed excision of hypoxanthine [AlkA] (Mus musculus) PubMed
7948.
Despite sequence and structural similarity with spermidine synthases from other organisms, a novel C-terminal beta-sheet and differences in the catalytic site of aminopropyltransferase were observed. [aminopropyltransferase TAAPT] (Mus musculus) PubMed
7949.
Tpk1 and Tpk2 isoforms regulate pseudohyphal development, biofilm structure, cell aggregation and adhesins expression. [Tpk1, Tpk2] (Mus musculus) PubMed
7950.
The role of WalRK and DacB in the remodeling of cell walls during division are reported.[WalRK; DacB] (Mus musculus) PubMed
7951.
Mutation in the COX5 gene alters utilization of amino acids as carbon source and ethanol formation. [Cox5] (Mus musculus) PubMed
7952.
RpoE and RpoS regulated gene expression during hyperosmotic stress. [RpoE] (Mus musculus) PubMed
7953.
Structural analyses of mannosylglycerate synthase complexes not only provide insight into metal coordination but also how lactate can function as an alternative acceptor to glycerate[mannosylglycerate synthase] (Mus musculus) PubMed
7954.
Oct3/4 initiates its own negative autoregulation through Cdx1 up-regulation to begin the repression of pluripotency in preparation for the onset of gastrulation and germ layer differentiation.[oct3/4, Xenopus laevis] (Mus musculus) PubMed
7955.
This work further clarifies the coordinated role of MarA and Rob in regulating the expression of the outer membrane porins.[MarA; Rob] (Mus musculus) PubMed
7956.
analysis of the C-terminal domain of a tyrosyl-tRNA synthetase that functions in group I intron splicing [TyrR, TyrS] (Mus musculus) PubMed
7957.
CCZ1, MON1 and YPT7 proteins are required for the cytoplasm to vacuole targeting pathway, and for nutrient starvationinduced non-specific macroautophagy in the methylotrophic yeast P. pastoris. [CCZ1, MON1,YPT7] (Mus musculus) PubMed
7958.
MyoB is essential for chitin deposition at nascent septation sites but not actin localization. [MyoB] (Mus musculus) PubMed
7959.
Pdr1 activates a broad repertoire of genes, specific mutations activates discrete subsets of this repertoire. [Pdr1] (Mus musculus) PubMed
7960.
In the distal germline, where MPK-1 is not activated, TRA-1 represses the male fate as NOS-3 functions in translational repression leading to inactivation of the FEM-CUL-2 ubiquitin ligase. (Mus musculus) PubMed
7961.
a bicarbonate transport metabolon proposed for the interaction between CAII and NBCe1 does not work at least in Xenopus oocytes [NBCe1/SLC4a4] (Mus musculus) PubMed
7962.
Inactivation of rbp1 led to a great reduction in the acquired chill-light tolerance, while ectopic expression of rbp1 enabled the cyanobacterium to survive the chill-light stress without preconditioning.[rbp1] (Mus musculus) PubMed
7963.
All-atom molecular dynamics simulations were used to to obtain atomic-scale data on the effects of membrane interface lipid composition on PMP1 structure and tilt.[PMP1] (Mus musculus) PubMed
7964.
The provide evidence that a similar yet distinct process is taking place: the motor domain is precluding the tail domain from binding to cortical Num1. (Num1) (Mus musculus) PubMed
7965.
The recombinant form of UDP-galactopyranose mutase (UGM) was obtained in a soluble and active form and characterized. [UGM] (Mus musculus) PubMed
7966.
The distribution of HU in Caulobacter crescentus was investigated using a combination of super-resolution fluorescence imaging and spatial point statistics.[HU protein] (Mus musculus) PubMed
7967.
App1 is upregulated during glucose starvation. [App1] (Mus musculus) PubMed
7968.
the mechanism of penicillin-binding protein-catalyzed cross-linking of the bacterial cell wall [PBP 1b] (Mus musculus) PubMed
7969.
Depletion of mitochondrial acyl carrier protein in bloodstream-form causes a kinetoplast segregation defect. [ACP] (Mus musculus) PubMed
7970.
The structure of this functionally important region of calponin and its interaction with actin and calmodulin at amino-acid resolution, was mapped.[F-actin] (Mus musculus) PubMed
7971.
The authors report that expression of human herpesvirus 5 ORF94 protein leads to decreased 2',5'-oligoadenylate synthetase (OAS) expression in transfected cells with and without interferon stimulation.[ORF94] (Mus musculus) PubMed
7972.
Inactivation of atlS resulted in formation of long chains by the cells, markedly decreased autolytic capacity, poor biofilm formation, diminished tolerance of acid and oxidative stress, and decreased production of extracellular DNA (eDNA).[atlS] (Mus musculus) PubMed
7973.
a novel C. elegans longevity factor, SLCF-1, whose inactivation increased lifespan in worms (Mus musculus) PubMed
7974.
infection with East-Asian-type CagA H. pylori was more closely associated with gastric mucosal atrophy and gastric cancer than infection with non-East-Asian-type CagA H. pylori [CagA] (Mus musculus) PubMed
7975.
The study identified the embryonic isoform laminin-associated polypeptide 2 gamma, which was downregulated during development similarly to laminin-associated polypeptide 2 omega. [laminin-associated polypeptide 2] (Mus musculus) PubMed
7976.
Data show that Kluyveromyces lactis KlGalpha interacts with the adaptor protein KlSte50p [Ste50]. (Mus musculus) PubMed
7977.
These results suggest that the protein kinase B gene homologue pkbR1 mutant has defects in a system that changes the physiological dynamics in the prestalk cell region of a finger [pkbR1]. (Mus musculus) PubMed
7978.
Data show that the C. neoformans wsp1 mutant exhibited defects in growth, cytokinesis, chitin distribution, and endocytosis and exocytosis, and whose ability to cause lethal infection in a murine model of cryptococcosis was also attenuated. (Mus musculus) PubMed
7979.
Studies on the reaction mechanism revealed that PpoA uses two different heme domains to catalyze two subsequent reactions. Initially, the fatty acid substrate is dioxygenated at C8, yielding an 8-hydroperoxy fatty acid at the N-terminal domain. [PpoA] (Mus musculus) PubMed
7980.
The SmQnrR protein is a transcriptional repressor for the contiguous Smqnr and SmtcrA genes, and SmQnrR is a negative regulator of SmqnrR-SmtcrA operon expression.[QnrR] (Mus musculus) PubMed
7981.
CG-1A promotes condensation formation and cartilage development; knockdown of CG-1A inhibits the formation of skeletal elements CG-1A causes the aggregation of precartilage cells. [CG-1A] (Mus musculus) PubMed
7982.
The authors demonstrated by performing genetic studies as well as by using semipurified molecules that, in contrast to a previous report, both of these genes are required for optimum mutacin IV activity.[nlmA & nlmB] (Mus musculus) PubMed
7983.
Clusters of polarized photons indicated an anisotropy decay of single actomyosin motors of ~9s during muscle contraction.[Actomyosin] (Mus musculus) PubMed
7984.
fur mutations can affect metronidazole susceptibility by altering the balance among Fur's several competing activities.[fur] (Mus musculus) PubMed
7985.
[KdpDE]- important virulence regulator coordinating external K+ sensing and Agr signaling during pathogenesis (Mus musculus) PubMed
7986.
FbsA protein is composed of alpha helices predominantly and random coils to a lesser extent. (Mus musculus) PubMed
7987.
Ccr4-Not has previously unrealized functional connections to the mRNA processing/export pathway.[Ccr4] (Mus musculus) PubMed
7988.
These data support a new model of NS1 regulation in which the RNA binding domain remains dimeric throughout infection, while the effector domain switches between several quaternary states in order to expand its functional space.[NS1] (Mus musculus) PubMed
7989.
LitR caused by some photodependent mechanism induces the expression of TT_P0055 protein, which serves as a transcriptional activator for the crtB operon and hence causes the expression of carotenoid biosynthesis.[LitR] (Mus musculus) PubMed
7990.
These studies support the model that CidA and LrgA proteins are bacterial holin-/antiholin-like proteins that function to control cell death and lysis during biofilm development.[CidA] (Mus musculus) PubMed
7991.
Non-binding inhibitory antibodies reacted highly against the C-terminal end of the VAR2CSA molecule especially the highly polymorphic DBL6epsilon domain.[VAR2CSA] (Mus musculus) PubMed
7992.
In this study, relevant nucleotides of the casA regulatory region that mediate its LeuO transcriptional activation were identified.[LeuO & CasA] (Mus musculus) PubMed
7993.
a novel role for Rif1 in assisting the essential telomere protection function of the CST complex [RIF1, strain not found] (Mus musculus) PubMed
7994.
the bioinformatics data showing an unexpected similarity between NDM-1 and beta-lactamase II from Erythrobacter litoralis [NDM-1][ElBla2] (Mus musculus) PubMed
7995.
reaction mechanism involving different barrier energies [MutY] (Mus musculus) PubMed
7996.
In vivo, comparison of the Streptomyces lividans wild type and DeltaCsnR strains using beta-lactamase reporter genes showed that CsnR represses the expression of csnA and of its own gene.[CsnR & CsnA] (Mus musculus) PubMed
7997.
PAIR3 is required for bouquet formation, homologous pairing, normal recombination, and synaptonemal complex installation; PAIR3 localizes to the chromosome axis and is required for normal binding of PAIR2 to chromosome [PAIR3] (Mus musculus) PubMed
7998.
The authors have also shown that both MGT and SgtA interact with PBP2 and other enzymes involved in cell wall synthesis in a bacterial two-hybrid assay.[MGT & SgtA] (Mus musculus) PubMed
7999.
role of the cofactor pyridoxal-5'-phosphate and its binding domain in stability and subunit assembly of phosphoserine aminotransferase [PSAT] (Mus musculus) PubMed
8000.
Two mitogen activated kinase kinase genes, MKK1 (Tb927.3.4860) and MKK5 (Tb927.10.5270), are not essential in the pathogenic bloodstream stage of Trypanosoma brucei, either in vitro or in vivo [MKK1, MKK5] (Mus musculus) PubMed
8001.
Pga1 triggers germination in response to carbon sources and affects negatively resistance to different stress conditions. [Pga1] (Mus musculus) PubMed
8002.
at the entrance of the death phase carbon-metabolizing enzymes [such as the TCA cycle enzymes Mqo2 (malate: quinone oxidoreductase) and FumC/CitG (fumarate hydratase)] are carbonylated to a larger extent in the clpC mutant.[clpC] (Mus musculus) PubMed
8003.
Nma is involved in apoptosis but not in stress adaptation.[Nma] (Mus musculus) PubMed
8004.
SOX2 is a novel flavin-dependent sulfhydryl oxidase with good pH and temperature stability. [SOX2] (Mus musculus) PubMed
8005.
crystal structure of Thermus thermophilus SecDF at 3.3 A resolution, revealing a pseudo-symmetrical, 12-helix transmembrane domain belonging to the RND superfamily and two major periplasmic domains, P1 and P4 [secDF] (Mus musculus) PubMed
8006.
alternative splicing of Saccharomyces cerevisiae SRC1 pre-mRNA is promoted by the conserved ubiquitin-like protein Hub1[Hub1] (Mus musculus) PubMed
8007.
These data suggest an early co-circulation of genetically distinct A/HNINv variants and emphasize the importance of a close molecular surveillance to detect rapidly the spread of new viral variants and to define their epidemiological impact. (Mus musculus) PubMed
8008.
We show here that co-expression of PpRSL1 and PpRSL2 is sufficient to transform gametophore cells into rhizoid cells, indicating that PpRSL1 and PpRSL2 expression is sufficient for rhizoid system development. [RSL1,RSL2] (Mus musculus) PubMed
8009.
AGL11 is the major functional candidate gene for seedlessness. [AGL11] (Mus musculus) PubMed
8010.
Cell-cycle-dependent localization of human cytomegalovirus UL83 phosphoprotein in the nucleolus and modulation of viral gene expression in human embryo fibroblasts in vitro (Mus musculus) PubMed
8011.
In this study, plate assay revealed that Xanthomonas campestris pv. campestris possesses pectin methylesterase activity encoded by pmeA and that its expression is controlled by Clp and RpfF.[pmeA] (Mus musculus) PubMed
8012.
Constitutive activation of GNA1 or GNA3 in the absence of ENVOY leads to constitutive G-alpha activation in darkness. [ENVOY, GNA1, GNA3] (Mus musculus) PubMed
8013.
This study revealed that a single BRC motif in BRCA2is sufficient to bind to RAD51 paralogues.[BRCA2 & RAD51] (Mus musculus) PubMed
Noise exposure triggered activation of caspase 3 in apoptic hair cells. (Mus musculus) PubMed
8016.
These results extend to A. thaliana alpha(5) the range of HcPro-interacting proteasomal subunits, and suggest that HcPro may modulate its associated RNase activity which may contribute to an antiviral response.[HcPro] (Mus musculus) PubMed
8017.
Report the relationship between infections of HPV16 EP variants and cervical squamous cell carcinoma in young Chinese women. (Mus musculus) PubMed
8018.
Uremic serum enabled NF-kappaB p65 nuclear translocation and increased NF-kappaB DNA binding activity in cultured aortic endothelial cells. (Mus musculus) PubMed
8019.
The soluble periplasmic domain of CcmE demonstrated no affinity for the Zn- or Sn-containing protoporphyrins and low affinity for Mn(ii)-protoporphyrin IX. [CcmE] (Mus musculus) PubMed
8020.
BgsB is a glucosyltransferase that synthesizes monoglucosyldiacylglycerol. Its inactivation profoundly affects cell membrane composition and has secondary effects on lipoteichoic acid biosynthesis.[BgsB] (Mus musculus) PubMed
8021.
Rum1 encodes a canonical Aux/IAA protein that is required for the initiation of embryonic seminal and post-embryonic lateral root initiation in primary roots of maize. [RUM1] (Mus musculus) PubMed
8022.
A patch of conserved surface residues contributed by both IFT25 and IFT27 is found adjacent to the GTP-binding site and could mediate the binding to other IFT proteins as well as to a potential GTPase-activating protein.[IFT25 & IFT27] (Mus musculus) PubMed
8023.
Iodotyrosine dehalogenase-1 was found to be expressed during gastrulation to neurulation in developing chick embryo and was postulated to be a regulator of cell specific deiodination involved in iodine turnover. [DEHAL1] (Mus musculus) PubMed
8024.
Phenotypic analyses following titration of EzrA levels in Staphylococcus aureus have shown that the protein is required for peptidoglycan synthesis as well as for assembly of the divisome at the midcell and cytokinesis.[EzrA] (Mus musculus) PubMed
8025.
The authors show that Bca1 controls an early step in complex III assembly and that the supra-molecular organization of Bca1 is dependent upon the assembly level of complex III.[Bca1] (Mus musculus) PubMed
8026.
The ZC3H18 gene is not essential in bloodstream forms, but in an in vitro model of differentiation, depletion of ZC3H18 delayed the transformation of bloodstream-form trypanosomes to the procyclic form that grows in the Tsetse fly.[ZC3H18] (Mus musculus) PubMed
8027.
Intraamniotic IL-1alpha causes an acute detrimental inflammatory response in the ileum and a disturbed balance between T-effector and FoxP3+ cells may contribute to this process.[IL-1alpha] (Mus musculus) PubMed
8028.
how the combination of several pivotal parameters can all lead to strand switches during DNA synthesis by HIV-1 RT was studied. [HIV-1 reverse transcriptase] (Mus musculus) PubMed
8029.
The crystal structures of apo Os4BGlu12, and its complexes with 2,4-dinitrophenyl-2-deoxyl-2-fluoroglucoside (DNP2FG) and 2-deoxy-2-fluoroglucose (G2F) were solved at 2.50, 2.45 and 2.40A resolution, respectively. [Os4BGlu12] (Mus musculus) PubMed
8030.
The functional role of GlLa in Giardiavirus-internal ribosome entry site mediated translation in Giardia, was studied.[GlLa] (Mus musculus) PubMed
8031.
The novel cGMP/PKG/ROS/calmodulin/CaMKII signaling pathway may regulate cardiomyocyte excitability by opening K(ATP) channels and contribute to cardiac protection against ischemia-reperfusion injury.[CaMKII] (Mus musculus) PubMed
8032.
These findings suggest that the SmeAB pump plays an important role in nodulation competitiveness by mediating resistance toward antimicrobial compounds produced by the host plant.[SmeAB] (Mus musculus) PubMed
8033.
Complementation of Deltacnb parasites with CnB restored thermotolerance and infectivity in both macrophages and animal models.[CnB] (Mus musculus) PubMed
8034.
In parasites expressing the DM10 domain of TcNDPK2 fused with green fluorescent protein, the fluorescence was localized in cytoskeleton and flagellum with an identical pattern to TcNDPK2.[NDPK2] (Mus musculus) PubMed
8035.
AtfA is permanently localized in the nucleus, while SakA accumulates in the nucleus in response to oxidative or osmotic stress signals or during normal spore development, where it physically interacts with AtfA.[SakA & AtfA] (Mus musculus) PubMed
8036.
Data suggest a dual regulation in which XESR5 produces a competent area for mesoderm formation by suppressing the gene expression of XESR1, while XESR1 sharpens the boundary of Xbra expressio: [XESR5] (Mus musculus) PubMed
8037.
crystal structure of BamD from the thermophilic bacteria Rhodothermus marinus refined to 2.15 A resolution is reported. [BamD] (Mus musculus) PubMed
The alpha-glucuronidase Agu1 is a member of a novel glycoside hydrolase family. [Agu1] (Mus musculus) PubMed
8040.
In the chick embryo, Ngn3 independently controls epithelium delamination and differentiation programs. [Ngn3] (Mus musculus) PubMed
8041.
Data show that three isolated genes: Defender Against Cell Death (Dad1), Polyubiquitin II (UbII) and Ferritin Heavy chain (fth1), are implicated in Programmed Cell Death (PCD)[UBII] (Mus musculus) PubMed
8042.
To understand the molecular mechanism of translocation, the molecular motions of EF-G were examined in solution by means of molecular dynamics simulations.[EF-G] (Mus musculus) PubMed
8043.
The extent of alpha-helical secondary structure coincided well, lending support for the two-stage model for membrane protein folding. [disulfide bond forming protein B] (Mus musculus) PubMed
8044.
Determined is the structure of the S. cerevisiae Nup133 C-terminal helical domain at 1.9 A resolution. [Nup133] (Mus musculus) PubMed
8045.
The sensitivity of [SWI+] to the activity of Hsp70 chaperone machinery may serve a regulatory role, keeping this prion in an easily-lost, meta-stable state. [Swi1] (Mus musculus) PubMed
8046.
results indicate NP swine-origin influenza virus(S-OIV)requires early start codon and V313 residue for optimal function-characteristics required for strong compatibility between S-OIV polymerase subunits and its indigenous NP over other strains [NP] (Mus musculus) PubMed
8047.
BC12/GDD1 is a kinesin-like protein with transcription regulation activity that mediates cell elongation by regulating the GA biosynthesis pathway. [GDD1] (Mus musculus) PubMed
8048.
AGO104 is required for proper chromatin condensation during meiosis, and acts to repress germ cell fate in somatic tissues. (Mus musculus) PubMed
8049.
vt2 plays a significant role in axillary meristem formation during inflorescence development in maize. [vt2] (Mus musculus) PubMed
8050.
The two-pore K+ channels TPKa and TPKb are localized to different types of vacuoles. (Mus musculus) PubMed
8051.
The study reports the solution structure of a cyanovirin-N homolog protein (CVNH) from Gibberella zea, GzCVNH, that shares 30% sequence identity with cyanovirin-N. [GzCVNH] (Mus musculus) PubMed
8052.
describe a novel Plasmodium vivax tryptophan-rich protein named PvTRAg33.5. It is expressed by blood stage(s) of the parasite and its gene contains two exons.[PvTRAg33.5] (Mus musculus) PubMed
8053.
Flounder growth hormone-releasing hormone (GHRH) plays roles in the bidirectional communication network between growth and immunity in fish. (Mus musculus) PubMed
8054.
results suggests that CBP1 expression is repressed during vegetative growth; transcriptional regulatory mechanism of CBP1 is discussed [CBP1] (Mus musculus) PubMed
8055.
MoVam7, like MoSec22, is a component of the SNARE complex whose functions in vacuole assembly also underlies the growth, conidiation, appressorium formation, and pathogenicity of M. oryzae.[MoVam7] (Mus musculus) PubMed
8056.
Individually expressed HSV-1 R1 (ICP6) shares, with HSV-2 R1, the ability to bind caspase-8 and to protect cells against death receptor-induced apoptosis.[ICP6] (Mus musculus) PubMed
8057.
Individually expressed HSV-1 R1 (ICP6) shares, with HSV-2 R1, the ability to bind caspase-8 and to protect cells against death receptor-induced apoptosis.[ICP10] (Mus musculus) PubMed
8058.
Txl1 and Txc1 are proteasome co-factors connected with oxidative stress. [Txc1] (Mus musculus) PubMed
8059.
The TgVTC2 mutant showed dramatically reduced polyphosphate accumulation, a defect restored by introduction of TgVTC2 to the mutant [TgVTC2] (Mus musculus) PubMed
8060.
MADS3 regulates male reproductive development at least in part through regulating ROS homeostasis. [MADS3] (Mus musculus) PubMed
8061.
Results suggest that PTB/PID-containing Ci-Noto4 is essential for midline intercalation of notochord cells in embryos: [Noto4] (Mus musculus) PubMed
8062.
A C2 domain protein kinase initiates phagocytosis in the protozoan parasite Entamoeba histolytica. (Mus musculus) PubMed
8063.
Mutation of the staphylococcal accessory regulator limits the accumulation of alpha-toxin and phenol-soluble modulins in Staphylococcus aureus isolates of the USA300 clonal lineage.[sarA] (Mus musculus) PubMed
8064.
crystals of ThiM belonged to the primitive space group P1, with unit-cell parameters a = 62.06, b = 62.40, c = 107.82 A, alpha = 92.25, beta = 91.37, gamma = 101.48 degrees [ThiM] (Mus musculus) PubMed
8065.
The authors show that TraB constitutes a novel conjugation system that is clearly distinguished from DNA transfer by a type IV secretion system.[TraB] (Mus musculus) PubMed
8066.
In Streptomyces coelicolor, both overexpression and deletion of cdgB inhibited aerial-mycelium formation, and overexpression also inhibited production of the antibiotic actinorhodin.[cdgB] (Mus musculus) PubMed
8067.
crystal belonged to space group P6(3), with unit-cell parameters a = b = 61.265, c = 361.045 A. The asymmetric unit may contain four to six CheW molecules (Mus musculus) PubMed
8068.
a 2.7 A resolution data set was collected from a single crystal of gp45[ gp45 ] (Mus musculus) PubMed
8069.
[glycoprotein gp120] While NBD-556 has a stable fluctuation profile, simulations indicate that its presence in the phenylalanine-43 cavity enhances overall mobility of gp120 envelope protein in comparison to CD4, miniprotein bound and uncomplexed forms. (Mus musculus) PubMed
8070.
HBZ binds with high affinity to the KIX domain of p300/CBP. The two phiXXphiphi motifs in the activation domain of HBZ mediate binding to a single surface of the KIX domain, the mixed-lineage leukemia binding surface. [HBZ protein, HTLV-1] (Mus musculus) PubMed
8071.
We show that the rat cytomegalovirus CD200 orthologue (e127) binds CD200R on rat peritoneal macrophages. [e127] (Mus musculus) PubMed
8072.
[HGPRT] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) catalyzes the phosphoribosylation of guanine and hypoxanthine, while Plasmodium falciparum HGPRT acts on xanthine as well. (Mus musculus) PubMed
8073.
EF2292 (VanV) was found not to be required for vancomycin resistance under the conditions tested, thus coding for another accessory protein in the vanB operon.[VanV] (Mus musculus) PubMed
8074.
FH5 is a type II formin-like protein encoded by Rice Morphology Determinant (RMD) that functions as an actin-nucleating protein by regulating rice plant morphology by modulating the microtubule- and microfilament-based cytoskeletal systems. (Mus musculus) PubMed
8075.
The dl2 vascular patterning distortions are strictly associated with a defective polar auxin transport activity and sensitivity to different classes of polar auxin transport inhibitors. [dl2] (Mus musculus) PubMed
8076.
Data show that OsSDIR1 could complement the drought sensitive phenotype of the sdir1 mutant and overexpressing transgenic Arabidopsis were more sensitive to ABA, indicating that the OsSDIR1 gene is a functional ortholog of SDIR1: [OsSDIR1] (Mus musculus) PubMed
8077.
Recombinant NT-Als9-2 from C. albicans (residues 18-329) was overexpressed in Escherichia coli, purified and crystallized. Diffraction data were collected to 2.0 A resolution. [NT-Als9-2] (Mus musculus) PubMed
8078.
here is the 2.0 A resolution structure of a family 32 carbohydrate-binding module of EndoD[endo-beta-1,4-N-acetylglucosamidase] (Mus musculus) PubMed
8079.
A gene encoding the Bombyx homolog of Drosophila Apterous (BmAp-A) protein is located 4.5 kb downstream of the distal breakpoint of the 1.5-Mb interstitial deletion. (Mus musculus) PubMed
8080.
HDR(homology-directed DNA repair) was stimulated through individual expression of the viral immediate-early protein IE1-72, mimicking full virus infection. [IE1-72] (Mus musculus) PubMed
8081.
Diffraction data from two crystal forms of beta-N-acetylhexosaminidase (primitive monoclinic and primitive tetragonal) were collected to resolutions of 3.2 and 2.4 A, respectively[beta-N-acetylhexosaminidase ] (Mus musculus) PubMed
8082.
AafA has been crystallized at pH 3.4 and diffraction data have been collected to 2.1 A resolution[AafA] (Mus musculus) PubMed
8083.
Amphioxus connectin has the domain structure of invertebrate connectin-like proteins at its N-terminus and that of vertebrate connectin at its C-terminus. [connectin, Branchiostoma floridae] (Mus musculus) PubMed
8084.
Rice may have evolved a CPD photolyase that functions in chloroplasts, mitochondria and nuclei, and that contains DNA to protect cells from the harmful effects of UV-B radiation. [CPD photolyase] (Mus musculus) PubMed
8085.
SasRGA4 is an NBS-LRR protein encoding gene that is necessary for Pia function. SasRGA5, adjacent to SasRGA4, is required for the full function of Pia that specifically recognizes AVR-Pia. [RGA4; RGA5] (Mus musculus) PubMed
8086.
PDP-1 modulates the expression of several insulin genes that are likely to feed into the IIS pathway to regulate DAF-16 activity. [PDP1] (Mus musculus) PubMed
8087.
These results suggested that HBZ has dual suppressive effects on IRF-1 function, which may contribute to HTLV-1 related pathogenesis.[HBZ] (Mus musculus) PubMed
8088.
The results suggest the functional role of SIZ1, a SUMO E3 ligase, in regulating rice anther dehiscence. [Oryza sativa] (Mus musculus) PubMed
8089.
The cytosolic glutamine synthetase 1;1 has a crucial role in ammonium assimilation and normal shoot growth. [OsGS1;1] (Mus musculus) PubMed
8090.
BUBR1 is required for ubiquitin-mediated proteasomal degradation of cell division cycle protein 20 in the G0 phase and maintains anaphase-promoting complex/cyclosome-CDC20 homolog 1 activity that regulates level of dishevelled for ciliogenesis [bubr1] (Mus musculus) PubMed
8091.
(S)-adenosylmethionine (SAM) is one of the two biosynthetic substrates for CqsA. CqsA couples SAM and decanoyl-coenzyme A to produce a previously unknown but potent quorum-sensing molecule, 3-aminotridec-2-en-4-one (Ea-CAI-1). (Mus musculus) PubMed
8092.
PCRMP3 and 4 play multiple roles during the Plasmodium life cycle; they are essential for the establishment of sporozoite infection in the mosquito salivary gland, and subsequently for development in hepatocytes.[pcrmp3,pcrmp4] (Mus musculus) PubMed
8093.
Taken together our results suggest a requirement for SNAP-29 in the fusion of post-Golgi vesicles with the recycling endosome for cargo to reach the cell surface. [SNAP 29] (Mus musculus) PubMed
8094.
PulD protomers normally cross the periplasm together with PulS bound to LolA but when the latter cannot be separated (due to the mutation in lolA), the PulD protomers form dodecamers that insert into the inner membrane.[PulD] (Mus musculus) PubMed
8095.
in gastric cancer patients infected with cagA-negative H. pylori, the s1m1 allelic combination of vacA was more frequent (54.4%), where s1 was present in 81.8% of the samples [VacA] (Mus musculus) PubMed
8096.
To maintain normal adhesion and biofilm function in response to exogenous oxidants msrA is upregulated, methionine oxidation of adhesins and perhaps other proteins is reversed, and adhesion and biofilm formation is maintained.[msrA] (Mus musculus) PubMed
8097.
study identified rainbow trout and Atlantic salmon IL-4/13A, a homologue of mammalian Th2 cytokine genes IL-4 and IL-13; salmonid IL-4/13A and GATA-3 were found highly expressed in thymus, gill, and skin [IL-4/13A] (Mus musculus) PubMed
8098.
The authors propose that a Msb2, Cek1 and Ace2 signalling pathway addresses PMT genes as downstream targets and that different modes of regulation have evolved for PMT1 and PMT2/PMT4 genes.[Msb2] (Mus musculus) PubMed
8099.
Amino-acid substitutions in AFLJ of A. oryzae induce inactivation at the protein level, and aflatoxin is not produced. (Mus musculus) PubMed
8100.
Only hyaluronic acid capsule and M1 protein shared with Sda1 an essentiality for the covRS switching phenotype. [covR,covS] (Mus musculus) PubMed
8101.
Crystal structure of Sa240: a ribose pyranase (RbsD) homolog with partial active site from Staphylococcus aureus. [Sa240] (Mus musculus) PubMed
8102.
stunter1 is a novel recessive maternal effect mutation that affects the size and germination efficiency of pollen. [stt1] (Mus musculus) PubMed
8103.
cloned three ER subtypes (ERalpha, ERbeta1, and ERbeta2), and examined their developmental expression in the gonads of females and males during embryonic and larval development [ERalpha] (Mus musculus) PubMed
8104.
OVP1 overexpression resulted in enhanced cold tolerance in transgenic rice, which was related to an increased integrity of cell membrane, decreased MDA content and accumulation of proline to higher level as compared with wild type rice seedlings. [OVP1] (Mus musculus) PubMed
8105.
These results suggest that Ptenb by antagonizing PI3 kinase and its downstream Akt1 and Cdc42 to regulate actin polymerization that is critical for proper cell motility and migration control during gastrulation in zebrafish.[Akt1] (Mus musculus) PubMed
8106.
The absence of ATX-3 activates the DAF-16 pathway leading to an overexpression of molecular chaperones, which yields knockout animals with an improved capacity for dealing with deleterious stimuli.[Ataxin-3] (Mus musculus) PubMed
8107.
FhbB crystals diffracted to 1.8 A resolution and belonged to space group P4(3)2(1)2 or P4(1)2(1)2, with unit-cell parameters a = b = 46.76, c = 167.68 A[FhbB] (Mus musculus) PubMed
8108.
A comparison of the binding mode and thermodynamic stability of the complexes of peptides from the C-terminal domains of HspA and Hpn proteins with four metals (HspA and Hpn). (Mus musculus) PubMed
8109.
diffraction data were collected to 3.51 A resolution from a crystal of selenomethionine-substituted dihydrouridine synthase in complex with tRNA[dihydrouridine synthase ] (Mus musculus) PubMed
8110.
The major virulence factor of S. aureus, protein A (SpA) binds directly to osteoblasts.[SpA] (Mus musculus) PubMed
8111.
Invasion of keratinocytes by S. aureus requires multiple high-affinity FnBRs within FnBPA.[FnBPA] (Mus musculus) PubMed
8112.
Report the influence of flavonoids on the voltage gating of a single alpha-hemolysin channel in planar lipid membranes. (Mus musculus) PubMed
8113.
crystal structures of YsxC from Thermotoga maritima and its complex with GDP were determined at maximal resolutions of 2.3 and 1.9 A[YsxC] (Mus musculus) PubMed
8114.
Cdc48-Npl4-Ufd1 is important for the maintenance of cell wall integrity in order for normal cell growth and division.[Cdc48, Npl4, Ufd1] (Mus musculus) PubMed
8115.
This study illustrates the importance of multiple intracellular regions of Gap1 in its secretion, transport activity, and down-regulation.[Gap1] (Mus musculus) PubMed
8116.
The results indicate that the isolated Sic1 kinase-inhibitor domain retains dynamic helical structure and populates collapsed states of different compactness.[Sic1] (Mus musculus) PubMed
8117.
crystal of the eIF5BDeltaN-eIF1ADeltaN complex diffracted to 3.3 A resolution and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 101.9, b = 120.9, c = 132.8 A[eIF1A and eIF1B] (Mus musculus) PubMed
8118.
E2-CD81 engagement may contribute to Hepatitis C virus-associated B cell lymphoproliferative disorders and insufficient neutralizing antibody production.[E2] (Mus musculus) PubMed
8119.
Results suggest that this staphyloccocal nuclease-like protein is the transcription factor that activates the transcription of some pathogenicity-related genes of E. histolytica.[URE1BP] (Mus musculus) PubMed
8120.
DEP3 is a patatin-like phospholipase A2 that might play a significant role in vascular bundle formation and inflorescence architecture. [DEP3] (Mus musculus) PubMed
8121.
The crystal 3D-structure of the Candida albicans CA3427 protein at 2.1 A resolution, is reported.[CA3427] (Mus musculus) PubMed
8122.
Isopeptides bonds were formed between Lys(63)-Asn(214) and Lys(243)-Asn(372) in PitB. [PitB] (Mus musculus) PubMed
8123.
results indicate that DypB has a significant role in lignin degradation in R. jostii RHA1, is able to oxidize both polymeric lignin and a lignin model compound, and appears to have both Mn(II) and lignin oxidation sites (Mus musculus) PubMed
8124.
These studies suggest a novel role for PDE5 in erythrocytes.[PDE5] (Mus musculus) PubMed
8125.
During the purification, three forms of catechol oxidase (39.3, 40.5 and 44.3 kDa) were obtained[catechol oxidase] (Mus musculus) PubMed
8126.
dTIEG regulates the activity of JAK/STAT pathway suggesting a conserved role of TIEG proteins as positive regulators of TGF-beta signalling.[TIEG] (Mus musculus) PubMed
8127.
The identification of a novel allele conferring enhanced fosfomycin resistance in a multidrug-resistant pathogen species in a rural river in British Columbia (fosA2). (Mus musculus) PubMed
8128.
The xa34(t) gene might be a novel recessive resistance gene that confers a new type of plant disease resistance based on our research. [xa34(t)] (Mus musculus) PubMed
8129.
identified a fibronectin-binding protein, GfbA which functions as an adhesin and invasin [GfbA] (Mus musculus) PubMed
8130.
The NO associated factor TaNOA might be involved in wheat responses to abiotic stresses. [NOA] (Mus musculus) PubMed
8131.
A broad characterization of S. agalactiae sortase C1 of the pilus island 2a is presented.[Sortase C1] (Mus musculus) PubMed
8132.
Transcriptome analyses revealed that Fusarium verticillioides expresses a protein (FvGLLc1) identical to a recently identified cytoplasmic/nuclear GNA-like lectin from maize (ZmGLLc)...not derived from a contaminating Fusarium species. [ZmGLLc] (Mus musculus) PubMed
8133.
The maturation and assembly of influenza A virus is controlled by the SUMO modification of M1 protein. [M1 protein] (Mus musculus) PubMed
8134.
Toxoplasma gondii GRA1 stimulates apoptosis of monocytes through autocrine TGF-beta1 signaling. (Mus musculus) PubMed
8135.
Deletion of atg1 results in impairment of autophagy, in an increased number of peroxisomes, an increase in the enzyme levels of the penicillin biosynthetic pathway, and enhanced production levels of penicillin. (Mus musculus) PubMed
8136.
ICP27 import does not appear to be regulated by arginine methylation. ICP27 import does not appear to be regulated by arginine methylation. ICP27 nucleus import does not appear to be regulated by arginine methylation. [ICP27] (Mus musculus) PubMed
8137.
Crystal structures of exo-arabinanase and of its complex with arabinobiose were determined at the high resolutions of 1.14 A to an R(work) of 10.7% (R(free) = 12.8%) and 1.04 A to an R(work) of 10.4% (R(free) = 12.5%). [exo-arabinanase] (Mus musculus) PubMed
8138.
Dmrt5 is an important player in ventral mesencephalic neural fate specification [Dmrt5] (Mus musculus) PubMed
8139.
An assay for pathogenicity in the adult rabbit diarrhea model suggested that VopF is involved in eliciting the diarrheal response in infected rabbits.[VopF] (Mus musculus) PubMed
8140.
role of Zta1p in the yeast adaptation to some stress types and the general functional significance of zeta-crystallins [Zta1p] (Mus musculus) PubMed
8141.
CLE12 overexpression or the exogenous application of its synthetic peptide inhibits root elongation, indicating that this 12-amino acid CLE12 peptide is biologically active.[CLE12] (Mus musculus) PubMed
8142.
1.9 A resolution crystal structure of GfcC, a periplasmic protein encoded by the gfc operon, which is essential for assembly of group 4 polysaccharide capsule (Mus musculus) PubMed
8143.
These results showed that the interaction between herpes simplex virus type 1 ICP27 and human TAP/NXF1 occurred in living cells upon head-to-tail intramolecular association of ICP27.[ICP27] (Mus musculus) PubMed
8144.
RT-PCR analysis was employed to analyze the differential expression patterns of nitrogen fixation genes under free-living and symbiotic conditions.[nix, fix] (Mus musculus) PubMed
8145.
Microarray analysis identified global transcriptional differences between glnR+ and glnR mutant strains under varying nitrogen conditions (GlnR). (Mus musculus) PubMed
8146.
Together, these findings suggest that Asp2 and Asp3 are likely to function in part as chaperones in the early phase of GspB transport.[Asp2, Asp3, GspB] (Mus musculus) PubMed
8147.
Report the characterization of Thermotoga maritima ferritin reveals an unusual subunit dissociation behavior and efficient DNA protection from iron-mediated oxidative stress. (Mus musculus) PubMed
8148.
The results link H(2) oxidation via the Hyb enzyme to growth, amino acid transport, and expression of periplasmic proteins that facilitate proton motive force-mediated transport across the outer membrane.[Hyb] (Mus musculus) PubMed
8149.
Mannosylphosphorylation of N- and O- linked glycans in Yarrowia lipolytica is mediated primarily by a single gene, MPO1 (mannosyl phosphorylation of oligosaccharides 1) without involvement of other genes. [MPO1] (Mus musculus) PubMed
8150.
Intestinal-enhanced presence of caspase-3+ cells was associated with an increased number of CD3epsilon+ cells located in the lamina propria-submucosa and within the epithelium.[CD3epsilon+] (Mus musculus) PubMed
8151.
Results suggest a possible role of SMc01113 in interactions mediated by the sRNA-pathway (SMc01113). (Mus musculus) PubMed
8152.
Hsl1 deletion mutants displayed an inability to synthesize/accumulate glycerol as a compatible solute. [Hsl1] (Mus musculus) PubMed
8153.
AMBER force field parameters were employed for the molecular dynamics simulation of rabbit 15S-lipoxygenase in aqueous solutions. [15S-lipoxygenase ] (Mus musculus) PubMed
8154.
The addition of the metabolite analogs of glycine betaine enhanced not only the rate constant but also the thermostability, salt tolerance, and substrate specificity of alpha-glucosidase. [alpha-glucosidase] (Mus musculus) PubMed
8155.
Substrate specificity of cdk1 gradually changes throughout the cell cycle. (Mus musculus) PubMed
Either Pep or GprA was shown to be necessary for fungal growth in protein medium at low pH. [Pep, GprA] (Mus musculus) PubMed
8162.
Pectin methylesterase (EC 3.1.1.11), a cell-wall remodeling enzyme, was activated in response to heat shock, and its elevated activity was related to the recovery of the HS-released Ca(2+) concentration.[PME] (Mus musculus) PubMed
8163.
The TolC enhancement of extreme-acid survival includes Gad induction, but TolC-dependent growth rates below pH 6.5 do not involve Gad.[GadA, GadB] (Mus musculus) PubMed
8164.
The ubiquitin-conjugating enzyme UbcX causes the ubiquitylation of XErp1, followed by its dissociation from the anaphase-promoting complex/cyclosome. [UbcX - Xenopus Ubch10 orthologue] (Mus musculus) PubMed
8165.
Both UDPDH and mshA gene expression are required for successful colonization of Euprymna tasmanica. [UDPDH] (Mus musculus) PubMed
8166.
The internalization of SLO-negative Streptococcus pyogenes was blocked by knocking down of the expression of clathrin or dynamin. [SLO] (Mus musculus) PubMed
8167.
These results indicate that TaNF-YB3 is involved in the positive regulation of a number of photosynthesis genes in wheat. [TaNF-YB3] (Mus musculus) PubMed
8168.
OsBBI1 modulates broad-spectrum resistance to blast fungus by modifying cell wall defence responses.[OsBBI1] (Mus musculus) PubMed
8169.
Cdc55 (PP2A) regulation of Net1 is essential for preventing early exit from meiosis I. (Mus musculus) PubMed
8170.
we provide in vitro evidence that a complex of the yeast protein disulfide isomerase Pdi1p and the mannosidase Htm1p processes Man(8)GlcNAc(2) carbohydrates bound to unfolded proteins, yielding Man(7)GlcNAc(2) [Pdi1 & Htm1] (Mus musculus) PubMed
8171.
Pho4 binding is not sufficient for transcriptional activation-a cooperative interaction between Pho2 and Pho4 specifies genes that are activated [Pho4] (Mus musculus) PubMed
8172.
[HTLV-1 envelope glycoprotein gp46] gp46 surface glycoprotein is recognized by neutralizing antibodies and cytotoxic T cells following a protective immune response, therefore it represents an attractive component for an HTLV-1 vaccine. (Mus musculus) PubMed
8173.
CWA1/BC1 plays a role in assembling secondary cell wall materials at appropriate sites, enabling synthesis of highly ordered secondary cell wall structure with solid and flexible internodes in rice.[CWA1] (Mus musculus) PubMed
8174.
The p25 subunit of dynactin is critical for dynein-mediated early endosome movement. [An5022/p25] (Mus musculus) PubMed
8175.
To reveal how Mot1 specifically disrupts TBP-DNA complexes, we combined crystal and electron microscopy structures of Mot1-TBP from Encephalitozoon cuniculi with biochemical studies. [Mot1 & TBP] (Mus musculus) PubMed
8176.
(chitinases ChiA and ChiB) The transglycosylation properties of family 18 chitinases ChiA and ChiB may be manipulated by mutations that affect the configuration of the catalytic machinery and the affinity for sugar acceptors. (Mus musculus) PubMed
8177.
a specific signal recognition particle-dependent substrate, Sec71p, is targeted exclusively to Ssh1p [Ssh1p] (Mus musculus) PubMed
8178.
data imply a new mechanism, actin-mediated sorting, in which WASH and the Arp2/3 complex polymerize actin on vesicles to drive the separation and recycling of proteins such as the V-ATPase [WASH] (Mus musculus) PubMed
8179.
these data suggest that OsJAR1 and OsJAR2 jasmonyl-L-isoleucine synthases are differentially involved in the activation of JA signalling in response to wounding and pathogen challenge in rice. [OsJAR1] [OsJAR2 ] (Mus musculus) PubMed
8180.
VasX localizes to the bacterial membrane and interacts with membrane lipids. We present VasX as a novel virulence factor of the T6SS. (Mus musculus) PubMed
8181.
The role of Cdc5 in the recombination checkpoint was analysed.[Cdc5] (Mus musculus) PubMed
8182.
propose VacA augments H pylori-induced mucosal inflammation in the stomach by causing programmed necrosis of gastric epithelial cells and release of proinflammatory proteins and may contribute to pathogenesis of gastric cancer and peptic ulceration [VacA] (Mus musculus) PubMed
8183.
The study identifies ATP-hydrolysis induced conformational changes in a complete ABC exporter (Sav1866) from Staphylococcus aureaus, using molecular dynamics (MD) simulations. [ABC exporter] (Mus musculus) PubMed
8184.
The study reports the crystal structure of An. gambiae serpin 2, the first serpin fold from a dipteran insect, in its native conformation to 1.75-A resolution. [serpin 2] (Mus musculus) PubMed
8185.
The analyses indicate that neither the semiopen nor an open conformation with native bottom-to-top flap ordering can effectively bind the substrate and reach to a closed conformation for hydrolysis. [HIV-1 protease] (Mus musculus) PubMed
8186.
ORF124L attenuates nuclear factor-kappaB activation and interacts with IkappaB kinase beta. [ORF124L] (Mus musculus) PubMed
8187.
These results are consistent with the interpretation that Npc1p is important for normal transport of ergosterol from the vacuole and is essential for proper membrane function under particular environmental conditions.[Npc1] (Mus musculus) PubMed
8188.
overexpression resulted in the generation of singlet oxygen and other reactive oxygen species and produced a chlorophyll-dependent regional cell death phenotype on leaves of rice seedlings [SGR] (Mus musculus) PubMed
8189.
delineated the erythrocyte binding domain (EBD) of one member of the reticulocyte binding protein homologue family, termed Py235 [Py235] (Mus musculus) PubMed
8190.
NS80 interacts with proteins NS38, VP4, and VP6. [NS80] (Mus musculus) PubMed
8191.
The X-ray structure of the anaerobic enzyme-substrate complex gives credit to substrate activation before the dioxygen fixation in the peroxo hole, where incoming and outgoing reagents (dioxygen, water, hydrogen peroxide) are handled. [urate oxidase] (Mus musculus) PubMed
8192.
Functioning of the fur Gene is Required for the acid tolerance response. [Fur] (Mus musculus) PubMed
8193.
The cag4 of Helicobacter pylori NCTC11637 has the enzyme activity of lytic transglycosylase. [cag4] (Mus musculus) PubMed
8194.
The crystal structure of Staphylococcus aureus MenH has been determined at 2 A resolution.[MenH] (Mus musculus) PubMed
8195.
a novel role for RedJ in facilitating transfer of a dodecanoyl chain from one acyl carrier protein to another en route to the key biosynthetic intermediate 2-undecylpyrrole [RedJ] (Mus musculus) PubMed
8196.
in vitro interaction of Pkh1 and Sch9 [PKH1][Pkh2][Pkh3][Sch9] (Mus musculus) PubMed
8197.
Three phosphorylation sites in Tub4 were found to be critical for Tub4 stability and microtubule organization.[Tub4] (Mus musculus) PubMed
8198.
The present results demonstrate that NS1 protein of Influenza A Virus interacts with heat hock protein Hsp90 and meidates the apoptosis induced by influenza A virus through the caspase cascade. (Mus musculus) PubMed
8199.
NS4A is identified as a critical determinant of flavivirus replication [NS4A] (Mus musculus) PubMed
8200.
Fur.Mn(2+), by binding to the upstream BoxA sequence, directly stimulates the expression of hilD in S. enterica.[fur, hilD] (Mus musculus) PubMed
8201.
NS4A is identified as a critical determinant of flavivirus replication [NS4A] (Mus musculus) PubMed
8202.
crystals of SM23 belonged to the I-centred tetragonal space group I4(1)22, with unit-cell parameters a = b = 126.6, c = 190.9 A[Sm23] (Mus musculus) PubMed
8203.
OsiICK1 and OsiICK6 interacted with OsCYCD, but differed in their interactions with CDKA. [OsiICK1, OsiICK6] (Mus musculus) PubMed
8204.
Hypoxia enhances mesenchymal stem cells to differentiate into osteogenic lineage cells and suggest that Cbfalpha1 may be negatively regulated by HIF-1alpha.[Cbfalpha1] (Mus musculus) PubMed
8205.
data implicate the Ebp pili as having some role in collagen adherence, albeit less than that of Ace, and a very major role in fibrinogen adherence[ebpA, ebpB, ebpC] (Mus musculus) PubMed
8206.
Two-component system RgfA/C activates the fbsB gene encoding major fibrinogen-binding protein in highly virulent CC17 clone group B Streptococcus.[RgfA/C protein, S.agalactiae; fbsB protein, S.agalactiae] (Mus musculus) PubMed
8207.
Ebp pili, are highly conserved and mediate adherence to platelets, suggesting that Ebp pili may be a reasonable immunotherapeutic target for prevention or possibly treatment of endocarditis caused by this species. [ebp] (Mus musculus) PubMed
8208.
evidence that in exponentially growing Salmonella enterica serotype Enteritidis, Dps is vital for protection against common killing mechanism of bactericidal antibiotics, a mechanism manifested by hydroxyl radical production via Fenton reaction [Dps] (Mus musculus) PubMed
8209.
The results reveal that NumA1 is a true nucleolar protein and the only nucleolar calmodulin-binding protein identified in Dictyostelium. The possible use of nuclear/nucleolar localization signal-mediated drug targeting to nucleoli is discussed. (NumA1) (Mus musculus) PubMed
8210.
Cohesin inactivation alters the expression of positionally clustered genes. (Mus musculus) PubMed
8211.
The investigators used the Streptococcus suis Dps-like peroxide resistance protein (SsDpr) to study the properties of the iron core in the wild-type protein and in four mutants (E64A, E67A, E68A, and E75A). [Dps-like peroxide resistance protein] (Mus musculus) PubMed
8212.
The study dissected the nucleotide cycle of the isolated helicase-like domain of T. maritima reverse gyrase, the influence of DNA on the nucleotide cycle, as well as coupling between DNA and nucleotide binding. [reverse gyrase] (Mus musculus) PubMed
8213.
A genome-wide transcriptional analysis identified genes upregulated in response to GTS1 induction, most of which were found to be regulated by the Tup1-Cyc8 co-repressor. [GTS1][Tup1][Cyc8] (Mus musculus) PubMed
8214.
Data suggest that eukaryotes with regional centromeres make use of different strategies for maintenance of CenH3 at centromeres, and we suggest a model in which centromere proteins nucleate at the core but require DIM-5 and HP1 for spreading. (Mus musculus) PubMed
8215.
results suggest that Hbx4 modulates DdCAD-1-mediated cytokinesis and cell-type proportioning [DdCAD-1] (Mus musculus) PubMed
8216.
gliG was found not to be involved in fungal self-protection against gliotoxin [gliG] (Mus musculus) PubMed
8217.
Complementation of the rice expansin 17(OsEXPA17) mutant with other root hair Expansins (OsEXPA30 and Arabidopsis EXPA7) can restore root hair elongation, indicating functional conservation of these root hair EXPAs in monocots and dicots. [EXPA17] (Mus musculus) PubMed
8218.
Polymorphisms of the Cytochome b gene show that there are distinct genotypes within Colombian Trypanosoma cruzi I populations. [Cytb] (Mus musculus) PubMed
8219.
There was a noticeable length polymorphism in PvMCA1 of P. vivax isolates, linked to the presence of tandem repeat units in the intronic region of the gene. [metacaspase 1] (Mus musculus) PubMed
8220.
PpPRR2 serves as a clock component in P. patens [PRR2] (Mus musculus) PubMed
8221.
purified and characterized a heterologously expressed gene product of AO090103000153 [OcpC] (Mus musculus) PubMed
8222.
AipA colocalized with Abp1 at the tip region, suggesting that AipA functions in endocytosis. [AipA] (Mus musculus) PubMed
8223.
Identification and expression of soul/p22HBP genes in zebrafish (Mus musculus) PubMed
8224.
hnRNP K is the nexus of a novel post-transcriptional regulatory module controlling the synthesis of proteins that integrate all three cytoskeletal polymers to form the axon. (Mus musculus) PubMed
8225.
Local accumulation or high levels of expression of EndoS in certain Streptococcus pyogenes strains may contribute to virulence.[EndoS] (Mus musculus) PubMed
8226.
A phiSM101 muramidase gene (psm) revealed by this study can be assumed to encode an N-acetylmuramidase, since the N-terminal catalytic domain deduced from the gene shows high homology of those of N-acetylmuramidases.[psm] (Mus musculus) PubMed
8227.
Plzf was found to be localized in the nucleus of both type A and type B spermatogonia until the 8-cell clone. (Mus musculus) PubMed
8228.
Trigger factor plays an important part in the pathogenesis and stress tolerance of S. suis serotype 2 infection. [tig] (Mus musculus) PubMed
8229.
Psy-A1 alleles control flour yellowness in Australian hexaploid wheat genotypes. [phytoene synthase 1] (Mus musculus) PubMed
8230.
Rsn1 is a cytokinin-O-glucosyltransferase that controls sensitivity of rice to a necrosis-inducing phytotoxin from Rhizoctonia solani. [Rsn1] (Mus musculus) PubMed
8231.
The ds1 gene encodes Leucine-Rich Repeat Receptor Kinases (LRR-RKs) and is involved in the resistance/susceptibility to target leaf spot. [ds1] (Mus musculus) PubMed
8232.
In this study, the ncgl1108 (named as pheP (Cg)) was identified as a new L-Phe specific transporter from Corynebacterium glutamicum RES167.[pheP] (Mus musculus) PubMed
8233.
Determined is the crystal structure of Leishmania major MIX to a resolution of 2.4 A. MIX forms an all alpha-helical fold comprising seven alpha-helices that fold into a single domain. [MIX] (Mus musculus) PubMed
8234.
A stem rust resistance gene was mapped to the long arm 6V#3L in T6AS.6V#3L and was designated as Sr52. [Sr52]. (Mus musculus) PubMed
8235.
These data indicate that PAF enhances conidiation in Penicillium chrysogenum by modulating the expression of brlA, the central regulatory gene for mitospore development.[PAF] (Mus musculus) PubMed
8236.
[2 genes]The structure of Lsp1 and Pil1 consists mainly of a banana-shaped BAR domain. (Mus musculus) PubMed
8237.
interference with mouse ATF6beta-dependent immune responses is a novel pathogenic mechanism induced by Toxoplasma gondii virulence factor ROP18 (Mus musculus) PubMed
8238.
Dysfunction of homogentisate oxygenase (VC1345) causes homogentisate accumulation and pigment formation in naturally pigmented strains of Vibrio cholerae.[homogentisate oxygenase] (Mus musculus) PubMed
8239.
These results suggest that the O-acetylesterase is probabbly essential for the synthesis of capsular Neu5Ac in S. suis. [NeuA] (Mus musculus) PubMed
8240.
the structural basis for the functional cooperation of a helicase domain with a DNA topoisomerase in reverse gyrase [reverse gyrase] (Mus musculus) PubMed
8241.
the histone deacetylase Sir2 plays a role in chromosomal position effects across the chromosome.[Sir2] (Mus musculus) PubMed
8242.
Both heads of one kinesin dimer are microtubule-bound at submicromolar ATP concentrations.[Kinesin] (Mus musculus) PubMed
8243.
Most importantly, when the point mutation converting Arg 19 to Leu in V1 was introduced into the full-length tomato yellow leaf curl virus-Israel genome, it disrupted its ability to cause symptoms.[V1] (Mus musculus) PubMed
8244.
These data support the functional characterization of SO2426 as a positive regulator of siderophore-mediated iron acquisition.[SO2426] (Mus musculus) PubMed
8245.
This report demonstrates the significant role Ohr and OhrR proteins play in bacterial stress resistance against organic peroxides in Sinorhizobium meliloti.[Ohr and OhrR] (Mus musculus) PubMed
8246.
A steady-state analysis shows that high light repression can indeed occur at intermediate oxygen levels if PpsR is reduced on a faster timescale than AppA and if the electron transfer from AppA to PpsR is effectively irreversible.[PssR, AppA] (Mus musculus) PubMed
8247.
The results indicate that both Nax genes have the potential to improve the salt tolerance of bread wheat.[Nax1, Nax2] (Mus musculus) PubMed
8248.
DdCAD-1 influences the sorting behavior of cells in slugs by its differential distribution on the prestalk and prespore cells.[DdCAD-1] (Mus musculus) PubMed
8249.
data indicate a conservation of the biochemical mechanisms of proliferating cellular nuclear antigen-mediated interactions between metazoa, yeast and parasitic protozoa [proliferating cellular nuclear antigen ] (Mus musculus) PubMed
8250.
distinct structural and antigenic properties of kappa-5 glycans suggest a specific role for kappa-5 in schistosome egg immunogenicity. [kappa-5] (Mus musculus) PubMed
8251.
Cys-520 and Cys-574 are not likely to be involved in the catalytic mechanism of thioredoxin glutathione reductase [thioredoxin glutathione reductase] (Mus musculus) PubMed
8252.
The glutamate-139 residue of V-ATPase NtpK subunit is indispensable for its enzymatic activity that is linked with the salt tolerance. [NtpK] (Mus musculus) PubMed
8253.
HmrA is a peptidase that participates in resistance mechanisms in vivo in the presence of beta-lactams (Mus musculus) PubMed
8254.
integrase-induced intramolecular conformational change in the viral DNA ends [integrase] (Mus musculus) PubMed
8255.
The formation of the rice prolamin-containing protein body I is initiated by the accumulation of CysR10. [CysR10] (Mus musculus) PubMed
8256.
These experiments showed that the NH2-terminal of the classical swine fever virus NS2 protein was highly hydrophobic and the protein localized in the endoplasmic reticulum. (Mus musculus) PubMed
8257.
The products of both easC (catalase) and easE (FAD-dependent oxidoreductase) are required for conversion of N-methyl-4-dimethylallyltryptophan (N-Me-DMAT) to chanoclavine-I. (Mus musculus) PubMed
8258.
By replacing rat cardiac troponin I (cTnI) in a mammalian cTn complex with trout cTnI it was demonstrated that this protein increases the Ca2+ affinity and reduces the influence of PKA phosphorylation on the Ca2+ affinity of the cTn complex.[PKA] (Mus musculus) PubMed
8259.
PKA treatment phosphorylated myosin light chain 2 but not cTnI or cardiac myosin binding protein C. Function of trout cardiac contractile element is altered by PKA phosphorylation in a manner different from that in mammalian heart.[PKA] (Mus musculus) PubMed
8260.
Ixr1, but not Dun1, is required for the proper RNR1 expression both during an unperturbed cell cycle and after DNA damage [Ixr1 and Rur1][strain not found] (Mus musculus) PubMed
8261.
that Est3 acts downstream of both Est2 and Est1 and that the putative activation function of Est1 can be explained by its role in recruiting Est3 to telomeres [Est3, and Est1] [strain not found] (Mus musculus) PubMed
8262.
This paper tested the hypothesis that overexpression (OX) of GS1 in rice improves utilization N use efficiency.[Glutamine synthetase 1] (Mus musculus) PubMed
8263.
interaction between Rtt107 and the SMC5/6 [Rtt107][SMC5][SMC6] (Mus musculus) PubMed
8264.
The specific activity of the SCR II E228S variant was increased approximately 7-20 times for acetophenones. [SCR II] (Mus musculus) PubMed
8265.
SCR and RCR mainly distributed in the intracellular membrane and cytoplasm. [SCR and RCR] (Mus musculus) PubMed
8266.
crystal structure of the 30 K protein from the silkworm Bombyx mori reveals a new member of the beta-trefoil superfamily. [Bmlp7] (Mus musculus) PubMed
8267.
Reduced HSP82 expression markedly attenuates the virulence of Histoplasma yeast in vivo.[Hsp82] (Mus musculus) PubMed
8268.
Taken together, these data reveal that the targeting of NSvc4 to plasmodesmata exploits the early secretory pathway and the actin-myosin VIII motility system in the leaves of a non-host plant, Nicotiana benthamiana.[NSvc4] (Mus musculus) PubMed
8269.
Shigella flexneri type III secreted effector OspF inhibits c-Jun expression at the transcriptional level. [OspF] (Mus musculus) PubMed
8270.
Together, these results consistently demonstrate that MtrC and OmcA are the terminal reductases used by Shewanella oneidensis MR-1 for extracellular Cr(VI) reduction where OmcA is a predominant Cr(VI) reductase.[MtrC] (Mus musculus) PubMed
8271.
crystal structure of free and inhibitor bound plasmepsin I (Mus musculus) PubMed
8272.
These data show that the ShvR-regulated genes BCAS0208 to BCAS0201 are required for the rough colony morphotype, biofilm and pellicle formation, and virulence in Burkholderia cenocepacia.[ShvR] (Mus musculus) PubMed
8273.
biophysical properties of the NS1A ED from H3N2 influenza A/Udorn/307/1972 (Ud) virus in solution [NS1A] (Mus musculus) PubMed
8274.
The authors conclude that both AlpA and AlpB contribute to Helicobacter pylori laminin binding.[AlpA and AlpB] (Mus musculus) PubMed
8275.
The authors conclude that type 1 pilus expression in pneumococcus exhibits a bistable phenotype, which is dependent upon the molecular interplay between the RlrA and RrgA proteins.[ RlrA and RrgA] (Mus musculus) PubMed
8276.
Intranasal exposure to staphylococcal enterotoxin B in C57BL/6 wild-type mice caused acute lung injury characterized by vascular leak, cytokine storm, and infiltration of mononuclear cells in the lungs. [staphylococcal enterotoxin B] (Mus musculus) PubMed
8277.
These findings suggest that PfRH2a and, most likely, the other members of the RH family, depending on their processing stage, can engage different receptors at different stages of the invasion process.[RH2a] (Mus musculus) PubMed
8278.
The structural details and their comparison give new insights into substrate and activator binding to adenosine kinase at the molecular level.[adenosine kinase] (Mus musculus) PubMed
8279.
NCp7 binding and functional remodeling of the human anticodon stem and loop domain (hASL(Lys3)) were studied.[NCp7] (Mus musculus) PubMed
8280.
The conformation of a 27-residue Nt-CCR5 peptide, sulfated at Y10 and Y14, was studied both in its free form and in a ternary complex with deglycosylated gp120 and a CD4-mimic peptide.[gp120] (Mus musculus) PubMed
8281.
The inhibition of IN-DNA interaction by the LEDGF/p75 C-terminus may provide a novel strategy for the inhibition of HIV IN activity.[Integrase] (Mus musculus) PubMed
8282.
(211)KELQKQITK and (262)RRKAK regions of IN C-terminal domain are required for Impalpha3 interaction and HIV-1 cDNA nuclear import.[Integrase] (Mus musculus) PubMed
8283.
The expressed hepatitis E virus ORF1 gene product does not undergo proteolytic processing, indicating that the replicase precursor of HEV is potentially unique in this regard. (Mus musculus) PubMed
8284.
The results suggest that site I of HA33 is quite unique in that it mainly recognizes Neu5AcN-acetylneuraminic acid, and site II seems less important for the lectin specificity. [HA33] (Mus musculus) PubMed
8285.
A transgenic P. berghei, in which endogenous Pbdhfr allele was replaced with the mutant PfdhfrS108N, was generated and confirmed to have normal growth rate comparing to parental non-transgenic parasite and also confer resistance to pyrimethamine. [PfDHFR] (Mus musculus) PubMed
distinct histone H3 pairs of variants arose independently in each of these clades and in basidiomycetes [histone H3] (Mus musculus) PubMed
8288.
Hd1 and Ehd1 together control the number of primary branches in the panicle. [Ehd1] (Mus musculus) PubMed
8289.
Atg35 is a new Atg protein that relocates to the peri-nuclear structure and specifically regulates micropexophagic apparatus formation during micropexophagy (Mus musculus) PubMed
8290.
The functional characterization of a multidrug and toxin extrusion transporter (MATE2), from Medicago truncatula, is reported.[MATE2] (Mus musculus) PubMed
8291.
[nef] A rhesus macaque CD8-positive T cell line recognizes N-myristoylated peptides of simian immunodeficiency virus (SIV) nef; Nef peptide-specific T cells expand significantly in monkeys with simian immunodeficient virus (SIV) infection. (Mus musculus) PubMed
8292.
The analysis constitutes the first characterization of an Oligosaccharyltransferase from delta-proteobacteria involved in N-linked protein glycosylation. (Mus musculus) PubMed
8293.
activation of digestion by ILPs may also underlie the growth promoting effects of insulin and TOR signaling in other species [ILP3][TOR] (Mus musculus) PubMed
8294.
The high affinity and specificity of the S. cerevisiae Cdc13 DNA binding domain for single-stranded telomeric DNA are not widely shared by other fungal Cdc13 proteins.[Cdc13] (Mus musculus) PubMed
8295.
The N-terminal of influenza A virus PB1 mediates its binding to host RanBP5. (Mus musculus) PubMed
8296.
Fbp1 is essential for fungal sporulation and virulence in C. neoformans, which likely represents a conserved novel virulence control mechanism. [Fbp1] (Mus musculus) PubMed
8297.
Alanine substitutions within a linker region of the NS1 alter its subcellular localization and attenuate virus replication. [NS1] (Mus musculus) PubMed
8298.
the importance of Tyr13, Glu77 and Ala117 specific to plasmepsin V that facilitates the accommodation of arginine at P in the RxLxE/Q/D motif [plasmepsin V] (Mus musculus) PubMed
8299.
The lipid modifications on ornithine-containing lipids due to OlsD occur on the amide-linked fatty acyl chain.[OlsD] (Mus musculus) PubMed
8300.
Purification and biochemical characterization of a novel glutamyl endopeptidase (VSPase)secreted by a clinical isolate of Staphylococcus aureus. [VSPase] (Mus musculus) PubMed
8301.
Os API5 is a nuclear protein that interacts with two DEAD-box ATP-dependent RNA helicases, API5-INTERACTING PROTEIN1 (AIP1) and AIP2.[AIP1, AIP2] (Mus musculus) PubMed
8302.
Downregulation of BNR2 causes defects in sporangium formation and a decrease in the total spore number.[BNR2] (Mus musculus) PubMed
8303.
Ubp15's enzymatic activity is regulated by the N- and C-terminal domains that flank the catalytic core domain.[Ubp15] (Mus musculus) PubMed
8304.
NLS1 encodes a CC-NB-LRR protein that mediates both salicylic acid and NPR1-independent defense signaling pathways in rice. [NLS1] (Mus musculus) PubMed
8305.
The quorum sensing response is mediated by base pairing between Qrr sRNAs and hapR mRNA and Hfq stabilizes Qrr/hapR complex formation. [Hfq] (Mus musculus) PubMed
8306.
The present study identified and characterized, for the first time in an oenological Saccharomyces cerevisiae strain, a gene involved in foam formation, named FPG1 (foam-promoting gene).[FPG1] (Mus musculus) PubMed
8307.
Mid1, a mechanosensitive calcium ion channel, affects growth, development, and ascospore discharge in the filamentous fungus Gibberella zeae. [Mid1] (Mus musculus) PubMed
8308.
mutations of Tyr8, Gln50, and Met93 disrupt the ability of PixD dimers to interact with PixE to form a higher-order PixD(10)-PixE(5) complex.[pixE, PixD] (Mus musculus) PubMed
8309.
a mutant rice lesion initiation 1 (rlin1) encoding a putative coproporphyrinogen III oxidase in tetrapyrrole biosynthesis pathway [RLIN1] (Mus musculus) PubMed
8310.
show that Hfq cannot stably bridge the RNAs. Persistent ternary complexes only form when the two RNAs are complementary[Hfq] (Mus musculus) PubMed
8311.
Cdc31 displays one Ca(2+)/Mg(2+) mixed site in the N-terminal domain and two low-affinity Ca(2+) sites in the C-terminal domain.[Cdc31] (Mus musculus) PubMed
8312.
the Ceramide glucosyltransferase gene is indispensable in the germline and that an ample supply of GlcCer is needed for oocytes and fertilized eggs to maintain normal membranes and to proceed through the normal cell cycle. (Ceramide glucosyltransferase ) (Mus musculus) PubMed
8313.
Disruption of FIT2 genes reduced accumulation of triacylglycerols and reduced the formation of lipid droplets. [FIT2] (Mus musculus) PubMed
8314.
Transgenic lines with RNAi-suppressed SSIIa and SSIIIa exhibited changed grain development, and reduced short and long amylopectin chain contents. [SSIIa; SSIIIa] (Mus musculus) PubMed
8315.
The differences found in the phosphorylation status of Rab21 are related to water stress tolerance in Oryza sativa. (Mus musculus) PubMed
8316.
The mei4Delta mutant was found to arrest cell division with its telomeres clustered at the spindle pole body, demonstrating a role for Mei4 in telomere dispersion.[mei4] (Mus musculus) PubMed
8317.
Cir1 contributes to copper mediated enhancement of sexual filamentation. Cir1 influences the expression of mating. [Cir1] pheromone genes suggesting that this protein plays a role in the early phase of sexual development on V8 mating medium. (Mus musculus) PubMed
8318.
KLF6a and KLF7a as important mediators of optic nerve regeneration and suggest that not all induced genes are essential to mount a regenerative response (Mus musculus) PubMed
8319.
the same E3 ubiquitin ligase known to regulate Snail family proteins, Partner of paired (Ppa), also controlled Twist stability and did so in a manner dependent on the Twist WR-rich domain [ppa] (Mus musculus) PubMed
8320.
Differences in the relative contributions of cardiolipin synthase 1 (CLS1) and CLS2 to cardiolipin accumulation under different triggering conditions suggest differences in the role and regulation of these two enzymes.[CLS1; CLS2] (Mus musculus) PubMed
8321.
The alpha-synuclein motifs target distinct vesicles in cells by direct interaction with different lipid environments. (Mus musculus) PubMed
8322.
Aar2p acts as a phosphorylation-controlled U5 snRNP assembly factor that regulates the incorporation of the particle-specific Brr2p [Aar2, strains not in gene] (Mus musculus) PubMed
8323.
SBEIIa is necessary in producing an amylopectin structure amenable to degradation by starch metabolism enzymes.[Sbe2a] (Mus musculus) PubMed
8324.
identify catalytically important residues and show that the enzyme reaction proceeded through the two-step mechanism involving the formation of a covalent intermediate.[epoxide hydrolase ] (Mus musculus) PubMed
8325.
This study revealed a complex interdependency of Ca(2+) and phosphoinositide-specific phospholipase C activity, with phosphoinositide-specific phospholipase C being essential throughout gamete formation.[phosphoinositide-specific phospholipase C] (Mus musculus) PubMed
8326.
The five nucleotides identified are the target DNA-binding sequence of ART1.[ART1] (Mus musculus) PubMed
8327.
The recombinant protein based on gp82, the Trypanosoma cruzi metacyclic trypomastigote surface molecule that mediates cell adhesion/invasion, induced exocytosis in HeLa cells. (Mus musculus) PubMed
8328.
These data suggest that actin bundling may improve the ability of the myosin motor system for nanotransport applications.[Myosin II] (Mus musculus) PubMed
8329.
Comparative sequence analysis identified interspecies variable- and conserved-parts in pvs230, and provides evidence that Pvs230, particularly CRDs, has limited polymorphism. [Pvs230] (Mus musculus) PubMed
8330.
Using zebrafish we determined that zfhx1b was expressed in the developing liver during biliary growth and remodeling, and that morpholino antisense oligonucleotide-mediated knockdown of zfhx1b led to defects in biliary development. (Mus musculus) PubMed
8331.
Brown planthopper feeding rapidly initiated the ethylene signaling pathway and up-regulated Bphi008a transcript levels after 6 to 96 h of feeding.[Bphi008a] (Mus musculus) PubMed
8332.
H-NS have a higher relative binding affinity for the ctx promoter than for the tcpA promoter. [CTX, H-NS] (Mus musculus) PubMed
8333.
rice FT homologue Hd3a interacts with 14-3-3 proteins in the apical cells of shoots, yielding a complex that translocates to the nucleus and binds to the Oryza sativa (Os)FD1 transcription factor, a rice homologue of Arabidopsis thaliana FD [Hd3a] (Mus musculus) PubMed
8334.
glyceraldehyde-3-phosphate dehydrogenase 2 interacts with glutathione peroxidase 3 through its carboxyl-terminal domain both in vitro and in vivo [GAPDH2] (Mus musculus) PubMed
8335.
The results do not support the role of MEF2A as direct regulators of primary muscle fiber type differences. (Mus musculus) PubMed
8336.
The scratch2 protects neurons from apoptosis by maintaining Puma levels low during normal embryonic development.(Scratch2 protein) (Mus musculus) PubMed
8337.
The bioactive peptide, BSP-I, from chicken humoral immune system, might provide novel insights on linking between humoral immune system and development of effective immunotherapeutic strategies for treating human cancers diseases. (Mus musculus) PubMed
8338.
Transpirational demand triggers a dramatic increase in gene expression of OsPIP2;5. [OsPIP2;5] (Mus musculus) PubMed
8339.
Disrupting the IPT1 gene greatly reduced Candida adhesion to gingival epithelial cells, compared to the wild-type and revertant strains.[IPT1] (Mus musculus) PubMed
8340.
These results indicated that CIA6 is required for the formation of the pyrenoid and further supported the notion that the pyrenoid is required for a functional CO(2)-concentrating mechanism in C. reinhardtii.[CIA6] (Mus musculus) PubMed
8341.
Two functional domains of VvpS is essential for autolysis. [VvpS] (Mus musculus) PubMed
8342.
SpkG play essential roles in Synechocystis sp. for sensing the high salt signal directly.[SpkG] (Mus musculus) PubMed
8343.
Data indicate that ChpH is required for promoting aerial development: [ChpH] (Mus musculus) PubMed
8344.
previously undescribed roles for the Spt16 M-domain and extreme carboxy terminus in regulating interactions between Spt16 and chromatin during the process of transcription elongation [Spt16] (Mus musculus) PubMed
8345.
Bxi1p, like its metazoan homologs, is an ER-localized protein that links the unfolded protein response and programmed cell death [Bxi1p] (Mus musculus) PubMed
8346.
These results demonstrated the molecular adaptation of parasite NDKbs in order to exert their biological functions intra-parasite and when secreted by regulating ATP levels of host cells.[NDKb] (Mus musculus) PubMed
8347.
HCV NS3 protein is involved in the activation of the Notch-signaling pathway through the targeting to both SRCAP and p400 (Mus musculus) PubMed
8348.
Expression of PVX TGBp3 from a heterologous vector induces the same set of genes in N. benthamiana and Arabidopsis (Arabidopsis thaliana) leaves.[TGBp3] (Mus musculus) PubMed
8349.
FlgM and FliA controls flagellum number and is essential for efficient swimming and biofilm formation. [FlgM and FliA] (Mus musculus) PubMed
8350.
Overexpression of ZmWri1a increases the fatty acid content of the mature maize grain and the content of certain amino acids, of several compounds involved in amino acid biosynthesis, and of two intermediates of the tricarboxylic acid cycle.[ZmWri1a] (Mus musculus) PubMed
8351.
These findings suggest a diversified and conserved switch of PTC1/MS1 in regulating programmed male reproductive development in both dicots and monocots.[PTC1] (Mus musculus) PubMed
8352.
Diffusible factors released by Glomus intraradices induce OsCPK18 and OsCPK4 expression in rice roots.[OsCPK18] (Mus musculus) PubMed
8353.
These results demonstrated the molecular adaptation of parasite NDKbs in order to exert their biological functions intra-parasite and when secreted by regulating ATP levels of host cells.[NDKb] (Mus musculus) PubMed
8354.
Tyr10 is criticle for the catalytic activity of BceC . [BceC] (Mus musculus) PubMed
8355.
Data show that Cr-DapL L,L-diaminopimelate aminotransferase was dimeric in both solution and when crystallized: [DapL] (Mus musculus) PubMed
8356.
Structure of PomAB revealed two arm domains connected to a large base made of the transmembrane and cytoplasmic domains. [PomA, PomB] (Mus musculus) PubMed
the CRE1 regulatory range in Trichoderma reesei [CRE1] (Mus musculus) PubMed
8359.
OsSpo11-4 exhibited double-strand DNA cleavage activity and its enzymatic activity appears dependent on Mg(2+) and independent of OsTopVIB, despite its interaction with OsTopVIB.[OsSpo11-4, OsTopVIB] (Mus musculus) PubMed
8360.
The data suggest that the Rad3 helicase in C. albicans is the product of the orf19.7119 gene. (Mus musculus) PubMed
8361.
These data highlight the importance of PERK eIF2alpha kinase-dependent eIF2alpha phosphorylation in the intracellular development of Leishmania.[PERK & eIF2alpha] (Mus musculus) PubMed
8362.
XlnR is highly phosphorylated when it is active in transactivation [XlnR] (Mus musculus) PubMed
8363.
Periplasmic PomB fragments form a homodimer and that deletions in the PomB linker region cause growth impairment of the cells. [PomB] (Mus musculus) PubMed
8364.
Sgp2 is not associated with the major pilus subunit Sgp1 in the absence of SrtG. [Sgp2, SrtG] (Mus musculus) PubMed
8365.
The lack of urease activity in vitro is not solely due to the amber codon in ureD. [UreD] (Mus musculus) PubMed
8366.
Esp PAI is a self-transmissible element that requires the IntA integrase contained on this element for excision. [IntA, Esp] (Mus musculus) PubMed
8367.
This is the first report detailing complete plasmepsin 4 gene analysis from Indian P. vivax isolates.[PM4] (Mus musculus) PubMed
8368.
A hwp2 null mutant is more susceptible to increasing doses of hydrogen peroxide, unable to adhere efficiently to epithelial and endothelial cell lines and unable to form wild type biofilm levels.[hwp2] (Mus musculus) PubMed
8369.
Experimental evidence that SauUSI, a gene nearly identical to those found in S. aureus strains SA564 and UAMS-1, is a modification-dependent restriction enzyme that requires ATP or dATP for endonuclease activity. (Mus musculus) PubMed
8370.
The results presented in here suggest that GP63 protease plays a vital role in Trichomonas vaginalis infection process, but may not be related to the adherence of parasitic cells to their hosts.[GP63] (Mus musculus) PubMed
8371.
[VacA] Chronic infection of VacA-positive Helicobacter pylori may increase the risk for atrial fibrillation by inducing systemic inflammation. (Mus musculus) PubMed
8372.
The role of infectious bursal disease virus proteins in the activation of the P85alpha subunit of phosphatidylinositol 3-kinase and akt proto-oncogene are reported.[AKT] (Mus musculus) PubMed
8373.
The authors propose that as animals enter fertile adulthood, EGF signalling switches the mechanism for maintaining protein homoeostasis to an approach involving protein elimination via augmented ubiquitin proteasome system activity.[EGF] (Mus musculus) PubMed
8374.
Results suggest that the uncommon recognition determinant of two closely spaced tyrosines is a limiting factor in NFAT signaling via Syk association with Vav1 [Vav1]. (Mus musculus) PubMed
8375.
Ccrp59 and Ccrp1143 are essential for the maintenance of proper cell shape. [Ccrp59; Ccrp1143] (Mus musculus) PubMed
8376.
The chlamydia-specific hypothetical protein CT311 was detected both inside and outside of the chlamydial inclusions in Chlamydia trachomatis-infected cells.[CT311] (Mus musculus) PubMed
8377.
From this study it is evident that VPg can serve as a specific regulator of potato virus A expression by boosting the viral RNA amounts as well as the accumulation of viral translation products.[VPg] (Mus musculus) PubMed
8378.
PaaR is a repressor that controls the expression of the two operons composing the paa gene cluster in vitro. [PaaR] (Mus musculus) PubMed
8379.
VarS/VarA two-component system acts on a component of the phosphorelay pathway upstream of HapR to regulate HapR expression levels. [VarS, VarA, HapR] (Mus musculus) PubMed
8380.
The resulting HypF-N mutants have higher contents of alpha-helical structure at the site(s) of mutation in their pH-unfolded states, but such an increase does not correlate with a change of aggregation rate. [HypF-N] (Mus musculus) PubMed
8381.
Overexpression of ZmCCA1 functionally delays flowering in Arabidopsis.[CCA1] (Mus musculus) PubMed
8382.
Ska3/Rama1, occupies a unique domain in the outer kinetochore.[Ska3] (Mus musculus) PubMed
8383.
Our data demonstrate that CcpA has a significant effect on the capsule synthesis and virulence properties of S. suis. [CcpA] (Mus musculus) PubMed
8384.
These studies identified a number of potential sites of regulation within Atg1 and will serve as a framework for future work with this enzyme.[Atg1] (Mus musculus) PubMed
8385.
Neither pyruvate : ferredoxin oxidoreductase (PFO) nor hydrogenase localize to the mitosome, but are mostly found in the cytosol. [PFO, hydrogenase] (Mus musculus) PubMed
8386.
The specific binding component for prostaglandin F(2alpha) (PGF(2alpha)) that exists in the plasma membrane fraction of the oviduct uterus myometrium of laying hens was shown to possess receptor properties for PGF(2alpha).[PGF2alpha receptor] (Mus musculus) PubMed
8387.
crystal and molecular structures of the LL-diaminopimelate aminotransferase ) in the apo-form and the pyridoxal-5'-phosphate-bound form [LL-diaminopimelate aminotransferase] (Mus musculus) PubMed
8388.
Here, we solved the N5 structure, the last unknown structure group 1 serotype with a unique Asn147 residue in its 150-loop, demonstrating that it has an extended 150-cavity that closes upon inhibitor binding [neuraminidase] (Mus musculus) PubMed
8389.
study reports crystal structure of a Foldtype II d-serine deaminase and describes features of the active site essential for catalysis [d-serine deaminase ] (Mus musculus) PubMed
8390.
These data are consistent with rhesus cytomegalovirus Rh178 blocking protein translation of MHC-I heavy chains at a step prior to the start of translocation, thereby downregulating MHC-I at a very early stage of translation. (Mus musculus) PubMed
8391.
study describes that the possession of cytochrome c oxidoreductase (SOR)and the ability to utilize sulphite as an electron donor significantly influences bacterial motility, gene regulation, autoagglutination and the invasiveness of C. jejuni [SOR] (Mus musculus) PubMed
8392.
APx-R is structurally related to ascorbate peroxidases and is targeted to the chloroplast and mitochondria in rice. (Mus musculus) PubMed
8393.
These findings suggest that Staphylococcus aureus colony spreading requires the expression of agr, which is positively regulated by environmental carbon sources.[agr] (Mus musculus) PubMed
Fsr mediates Ace surface levels through its regulation of the metalloprotease gelatinase (GelE), which we showed directly cleaves Ace, subsequently impacting the ability of cells to adhere to collagen. [GelE, Ace] (Mus musculus) PubMed
8396.
Absence of RNase III leads to a significant increase in PNPase levels. [PNPase] (Mus musculus) PubMed
8397.
findings clearly indicate that the origin of NP determines Mx sensitivity and that human influenza viruses acquired adaptive mutations to evade MxA restriction [NP, H5N1 virus, H1N1 Virus] (Mus musculus) PubMed
8398.
results identify the cooperation between PB2 and PB1 as an important restricting factor for reassortment of in fl uenza viruses[PB1,PB2] (Mus musculus) PubMed
8399.
The tyrosine phosphatase homolog CtpA is necessary for viability in Caulobacter. One function of CtpA is to regulate PG biosynthesis or remodeling via dephosphorylation of tyrosine residues on target proteins. [CtpA] (Mus musculus) PubMed
8400.
MnSOD of E. faecalis contributes to survival of the bacterium in microglial cells by influencing their antimicrobial activity. [MnSOD] (Mus musculus) PubMed
8401.
SpiA gene is involved in both biofilm formation and virulence of S. enteritidis. [spiA] (Mus musculus) PubMed
8402.
TaCab1 is involved in the plant-pathogen recognition, symptom development, and the basal tolerance to biotic and abiotic stresses through the salicylic acid signaling pathway.[TaCab1] (Mus musculus) PubMed
8403.
Trm9p and Trm112p function together at the final step in formation of mcm(5)U in tRNA by using the intermediate cm(5)U as a substrate.[trm9] (Mus musculus) PubMed
8404.
Relative to the wild-type Tx/91-induced gene expression, the NS1 mutant virus induced enhanced expression of innate immune genes, specifically NF-kappaB signalling-pathway genes and IFN-alpha and -beta target genes. (Mus musculus) PubMed
8405.
Trypanosoma-Sub2 (Tryp-Sub2) is a component of mRNA transcription/export pathway in trypanosomes [TcSub2] (Mus musculus) PubMed
8406.
The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes. (Mus musculus) PubMed
8407.
show that two orthodenticle genes, otd1 and otd2, and hunchback act as maternal anterior patterning genes in the honeybee (Mus musculus) PubMed
8408.
MreB has a role in cell shape determination and binds directly to the cell membrane. (Mus musculus) PubMed
8409.
structure and nucleotide specificity of dihydrodipicolinate reductase [DapB] (Mus musculus) PubMed
8410.
The ability of the Sup35 and PrP repeats to support [PSI(+)] propagation stems from their amino acid composition, not their primary sequences.[Sup35] (Mus musculus) PubMed
8411.
Centromere-bound Scm3 aids recruitment of Cse4/H4 to assemble and maintain an H2A/H2B-deficient centromeric nucleosome. [Scm3] (Mus musculus) PubMed
8412.
Taken together, these findings suggest that MOPICE modulates the anti-monkeypox virus immune response and that this protein is not the sole virulence factor of the central African clade of monkeypox virus.[MOPICE] (Mus musculus) PubMed
8413.
Virus with PB2 D253N and Q591K induced more tumor necrosis factor alpha (TNF-alpha) in human macrophages, replicated better in differentiated normal human bronchial epithelial (NHBE) cells, and was more pathogenic for mice.[PB2] (Mus musculus) PubMed
8414.
The results suggest that expression of L of the DA strain of Theiler's murine encephalomyelitis virus plays an important role in the pathogenesis of Theiler's murine encephalomyelitis virus-induced demyelinating disease. (Mus musculus) PubMed
8415.
OsHDT1 may be involved in epigenetic control of parental genome interaction for differential gene expression.[OsHDT1] (Mus musculus) PubMed
8416.
The crystal structure of full length RrgB, solved by X-ray crystallography at 2.8 A resolution, is reported. (Mus musculus) PubMed
8417.
crystal of glucokinase in complex with glucose belonged to space group P6(2)22 or P6(4)22, with unit-cell parameters a = b = 109.19, c = 141.18 A. The crystal contained one molecule in the asymmetric unit[glucokinase ] (Mus musculus) PubMed
8418.
SucR was identified as the fourth transcriptional regulator involved in expression control of the adhA gene.[SucR] (Mus musculus) PubMed
8419.
shows that miR-200 activity is required for taste bud formation and in particular for Calb2b(+) cell formation[miR-200 ] (Mus musculus) PubMed
8420.
[Cph1; cyanobacterial phytochrome 1] This study describes the effects of divalent cations, pH, and light on the regulation of the autokinase activity of Cph1 and the subsequent control of phosphotransfer to the cognate response regulator Rcp1. (Mus musculus) PubMed
8421.
The binding of protein phosphatase 1 to the evolutionarily conserved RVSF motif of the kinetochore protein Spc105 is essential for viability by silencing the spindle assembly checkpoint. [Spc105] (Mus musculus) PubMed
8422.
three cytoskeletonrelated proteins, ARP3, ANXA1, and ANXA5, have been identified as being differentially regulated, in response to dietary change. [ARP3 and ANXA1 and ANXA5] (Mus musculus) PubMed
8423.
This study therefore expands the versatile nature of the NS1 protein in inhibiting interferon responses at multiple levels, by demonstrating for the first time that it occurs in a manner dependent on allele type. (Mus musculus) PubMed
8424.
The authors suggest that the sensory box protein, SO3389, is an O2/redox sensor that is involved in optimization of aerobic growth and transitions to anoxia in Shewanella oneidensis MR-1.[SO3389] (Mus musculus) PubMed
8425.
The authors conclude that GRD1 represents a novel enhancer of cellulase gene expression, which by coregulation with the major cellulase may act via optimization of inducing mechanisms.[GRD1] (Mus musculus) PubMed
8426.
The authors conclude that the dispersion of ND10 by major immediate-early protein 1 (IE1) appears not to be important for murine cytomegalovirus replication in a mouse-cell culture.[IE1] (Mus musculus) PubMed
8427.
Secondary envelopment did not proceed in the absence of functional M94, and capsids subsequently accumulated in the center of the cytoplasmic assembly complex.[M94] (Mus musculus) PubMed
8428.
(pyrrolysine tRNA synthetase) The origin of allostery and half-sites reactivity of activated pyrrolysine tRNA synthetase lies in subtle rearrangements of interactions and dynamics at a global level. (Mus musculus) PubMed
8429.
To examine the potential functional role of food vacuole-associated enolase, the authors showed the ability of the enolaseto complement a mutant Saccharomyces cervisiae strain deficient in enolase activity.[enolase] (Mus musculus) PubMed
8430.
The Schizosaccharomyces pombe WISH/DIP/SPIN90 ortholog dip1p is an actin-patch protein that regulates the temporal sequence of endocytic events. [dip1p] (Mus musculus) PubMed
8431.
The purified protein demonstrated transketolase activity with K(m) values of 0.2mM and 0.8mM respectively for xylulose 5-phosphate and ribose 5-phosphate.[transketolase] (Mus musculus) PubMed
8432.
Homology modeling of the LmTRYP6 was proposed to predict some functional property of this protein.[TRYP6] (Mus musculus) PubMed
8433.
In this study the authors show that, upon oxidative stress, Aft1 is transitorily internalized into the nucleus, followed by transcription activation of components of its regulon. (Mus musculus) PubMed
8434.
These results demonstrate that GRASP, a protein involved in unconventional protein secretion, is also required for polysaccharide secretion and virulence in Cryptococcus neoformans.[GRASP] (Mus musculus) PubMed
8435.
cellular IRF5 and vIRF3 interact, leading to the functional modulation of IRF5-mediated type I IFN expression and cell cycle regulation [IRF3] (Mus musculus) PubMed
8436.
rbMATE1 is a multispecific organic cation H(+) exchanger (Mus musculus) PubMed
8437.
These results suggest that OsPLDalpha is involved in salt tolerance in rice through the mediation of H(+)-ATPase activity and transcription.[OsPLDalpha, H+ ATPase] (Mus musculus) PubMed
8438.
Spectroscopic, electrochemical, and crystallographic results of IsdI are reported that provide evidence that this heme ruffling is essential to the catalytic activity of the protein.[IsdI] (Mus musculus) PubMed
8439.
The Galpha subunit of the heterotrimeric G protein complex from wheat (Triticum aestivum), GA3, and the calcium-binding protein, Clo3 which functions to enhance the GTPase activity of GA3. [GA3] (Mus musculus) PubMed
8440.
These results identify the binding of RON2 to the hydrophobic pocket of AMA1 as the step that commits Plasmodium merozoites to red blood cell invasion and point to RON2 as a potential vaccine candidate.[AMA1, RON2] (Mus musculus) PubMed
8441.
Nell-1 genes could promote new bone formation and maturation in the rabbit maxillary sinus model. (Mus musculus) PubMed
8442.
TORC1 can be substantially, if not fully, reactivated in an autophagy-dependent manner under ongoing starvation.[TORC1] (Mus musculus) PubMed
8443.
the unique folding of this conserved Sir3 AAA(+) domain generates novel surface regions that mediate Sir3-Sir4 and Sir3-nucleosome interactions [Sir3 and Sir4; strain not in database] (Mus musculus) PubMed
8444.
Catalase and superoxide dismutase-2 are particularly important for diapause female survival; elevation of catalase also contributes to protection of the ovaries. RNAi directed against forkhead transcription factor suppressed both enzymes.[Cat,Sod-2] (Mus musculus) PubMed
8445.
identification of a NCgl2130 gene of C. glutamicum as a novel succinate exporter that functions in succinate production, and designated sucE1 [sucE1] (Mus musculus) PubMed
8446.
aaNAT1 is more abundant in Ae. aegypti larval/pupal body, and aaNAT2 is more abundant in the head of adults. It appears that aaNAT1 is mainly involved in sclerotization and aaNAT2 in neurotransmitter inactivation.[aaNAT1,aaNAT2] (Mus musculus) PubMed
8447.
The calcineurin B-like protein-interacting protein kinases CIPK14 and CIPK15 reduced ROS production and regulate defense responses. [CIPK14, CIPK15] (Mus musculus) PubMed
8448.
Constituent-based models with an anisotropic elastin part characterize more accurately the mechanical properties of the arterial wall.[Elastin] (Mus musculus) PubMed
8449.
These results suggest that IR2 protein function requires the two N-terminal domains for binding DNA and TFIIB as well as the C-terminal residues 707 to 1116 containing the TBP-binding domain.[IR2] (Mus musculus) PubMed
8450.
we report a novel double Ig IL-1R related molecule (DIGIRR) from three model fish (Tetraodon nigroviridis, Gasterosteus aculeatus, and Takifugu rubripes) (Mus musculus) PubMed
8451.
membrane cholesterol plays an essential role in the binding of C. jejuni CDT subunits to membrane rafts, which promotes the pathogenic events in host cells[cdta, cdtb,cdtc] (Mus musculus) PubMed
8452.
These results suggest that the p300-acetylated lysines of BTas are important for transactivation of bovine foamy virus promoters and therefore have an important role in bovine foamy virus replication.[BTas] (Mus musculus) PubMed
8453.
S. Typhi STY1365 encodes a holin remnant protein that is involved in the stability of the bacterial envelope [STY1365; different strain] (Mus musculus) PubMed
8454.
cloning and characterization of Francisella tularensis MEP cytidylyltransferase [MEP cytidylyltransferase] (Mus musculus) PubMed
8455.
The results showed that NS1 of avian influenza virus H5N1 (A/chicken/Guangdong/1/2005) is able to bind to PSD-95, whereas NS1 of human influenza virus H1N1 (A/Shantou/169/2006) is unable to do so.[NS1] (Mus musculus) PubMed
8456.
human proximal tubule epithelial cell line, HK-2 cells, are differentially susceptible to the cytotoxic action of Shiga Toxin Types 1 and 2. [Stx1] and [Stx2] (Mus musculus) PubMed
8457.
Genetic analysis of LB4D indicated that the dwarf phenotype was controlled by a single semidominant dwarfing gene, which was named LB4D.[LB4D] (Mus musculus) PubMed
8458.
The relationship between oxygen input, physiology and gene expression of E. coli MG1655 and two isogenic mutants lacking succinate dehydrogenase (SDH) and fumarate reductase (FRD) activities was analyzed at different aerobiosis levels.[sdhC, frdA] (Mus musculus) PubMed
8459.
At day 7 and later, expression of cpo was much higher in diapausing vs. non-diapausing adults. In 2-month old diapause females transferred to diapause-terminating conditions, cpo expression declined.[cpo] (Mus musculus) PubMed
8460.
the TaSnRK2.7-A genomic region has evolved under extensive selection pressure during crop breeding [SnRK2.7-A] (Mus musculus) PubMed
8461.
suggesting that OsAM1 plays a fundamental role in building the proper chromosome structure at the beginning of meiosis[AM1] (Mus musculus) PubMed
8462.
These measurements support a cofilin-severing mechanism in which mechanical asymmetry promotes local stress accumulation and fragmentation at boundaries of bare and cofilin-decorated segments, analogous to failure of some nonprotein materials.[Cofilin] (Mus musculus) PubMed
8463.
Data indicate that p13 protein directly binds Tax, decreases Tax binding to the CBP/p300 transcriptional coactivator, and, by reducing Tax transcriptional activity, suppresses viral expression: [p13] (Mus musculus) PubMed
8464.
Neither Glu-286 nor active-site water likely constitutes the gating element proton pumping in cytochrome c oxidase.[Cco] (Mus musculus) PubMed
8465.
mechanism of oxygen reactivity in a heme and tyrosyl radical-containing fatty acid alpha-(di)oxygenase [fatty acid alpha-(di)oxygenase] (Mus musculus) PubMed
8466.
Expression analysis in 16 different tissues of fifth instar larvae and functional prediction using InterProScan suggested that BGIBMGA003864 was most likely to be the gene responsible for the sex-linked translucent (os) phenotypes. [BGIBMGA003864] (Mus musculus) PubMed
8467.
CagA in the stomach plays an important role in the migration of H. pylori-primed CD4(+) T cells in the gastric mucosa. [CagA] (Mus musculus) PubMed
8468.
this study shows the essentiality of T. brucei Stearoyl-CoA desaturase (SCD)[SCD] (Mus musculus) PubMed
8469.
A total of 441 differentially expressed genes, designated as XDGs (Xa21 mediated differentially expressed genes), were identified.[Xa21] (Mus musculus) PubMed
8470.
In developing ovaries, copy number of treh-2 mRNA per 1 copy of rp49 mRNA was 1000x higher than that of treh-1 mRNA. Trehalase activities enhanced by diapause hormone originate from treh-2 protein regulated at the transcriptional level.[diapause hormone] (Mus musculus) PubMed
8471.
two redundant genes, OsSUS5 and OsSUS7, evolved via duplication of a chromosome region and through the transposition of transposable elements. [OsSUS5 and OsSUS7] (Mus musculus) PubMed
8472.
BEST1 is a functional anion channel in the plasma membrane. [BEST1] (Mus musculus) PubMed
8473.
Spore production for ugtADelta was reduced to 1%, and spore germination was reduced to half. [ugtA] (Mus musculus) PubMed
8474.
Iwr1 plays an important role in preinitiation complex formation by all three nuclear RNA polymerases [Iwr1] (Mus musculus) PubMed
8475.
this study suggests that NleC is a unique virulence factor that impacts several aspects of in fl ammatory signaling [NleC] (Mus musculus) PubMed
8476.
Data suggest that TaMYB4 negatively regulates the lignin biosynthesis in wheat: [TaMYB4] (Mus musculus) PubMed
8477.
Heme-L-lysinate could attenuate atherosclerotic progression through upregulating HO-1 and HSP70 expression and increasing CO production. [HSP70] (Mus musculus) PubMed
8478.
local and global thermodynamic stability of the variant (1-165) of SlyD from Escherichia coli [SlyD] (Mus musculus) PubMed
8479.
Results describe the molecular analysis of partial cDNA sequences of sheep Peg10 and Xist. (Mus musculus) PubMed
8480.
Silencing of MtSAP1 by RNA interference (RNAi) showed that the function of the encoded protein is required for adequate accumulation of storage globulin proteins, vicilin and legumin, and for the development of embryos... [SAP1] (Mus musculus) PubMed
8481.
TheHra2 deletion mutant was deficient in adherence but not autoaggregation or invasion, pointing to a functional distinction from the autoagglutinin Hra1 and the Tia invasin.[Hra2] (Mus musculus) PubMed
8482.
Deletion of the SIT4 gene, which encodes for the catalytic subunit of type 2A ceramide-activated protein phosphatase in yeast, abolished the premature ageing and hydrogen peroxide sensitivity of isc1Delta cells.[SIT4 & isc1] (Mus musculus) PubMed
8483.
In a FRQ-sufficient background, the UV90 mutation causes damping of the free-running conidiation rhythm, reduction of the amplitude of the FRQ [Frequency] protein rhythm, and increased phase-resetting responses to both light and heat pulses.[FRQ] (Mus musculus) PubMed
8484.
An hlyU mutant was constructed, which exhibited an approximately 5-fold decrease in hemolytic activity on sheep blood agar with no statistically significant decrease in cytotoxicity of the wild-type strain.[hlyU] (Mus musculus) PubMed
8485.
The authors showed that purified YefM(Spn) antitoxin and the YefM-YoeB(Spn) toxin-antitoxin protein complex bind to a palindrome sequence encompassing the -35 region of the main promoter (P(yefM2)) of the operon.[YoeB] (Mus musculus) PubMed
8486.
These results suggest that m- and micro-calpain may be involved in colon epithelial cell death induced by E. histolytica.[m-calpain, micro-calpain] (Mus musculus) PubMed
8487.
OsPT8 is involved ininorganic phosphate homeostasis in rice and is critical for plant growth and development.[OsPT8] (Mus musculus) PubMed
8488.
Mutagenesis of the interchange thiol of NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase (2-KPCC) abolished all redox-dependent reactions of 2-KPCC (2-KPC carboxylation or protonation).[2-KPCC] (Mus musculus) PubMed
8489.
relative expression levels of IgD, IgM, and IgZ/T were measured in triplicate for zebrafish (Mus musculus) PubMed
8490.
Determined is the crystal structure of E.coli MnmC containing flavin adenine dinucleotide, at 3.0 A resolution. [MnmC] (Mus musculus) PubMed
8491.
The authors demonstrate that the Streptococcus pyogenes FbaB is essential and sufficient to trigger endothelial cell invasion via a Rac1-dependent phagocytosis-like uptake.[FbaB] (Mus musculus) PubMed
8492.
Gem1 ortholog Miro-1 localizes to sites of endoplasmic reticulum-mitochondrial contact, suggesting that some of the features ascribed to Gem1 may be evolutionarily conserved.[Gem1] (Mus musculus) PubMed
8493.
The complete attenuation of the SDH mutant for virulence in the mouse model and increased virulence mutant strains postcomplementation with SDH, indicated that the SDH surface export indeed regulates virulence.[SDH] (Mus musculus) PubMed
8494.
These results suggest that OsREC8 has several essential roles in the meiotic processes.[OsREC8] (Mus musculus) PubMed
8495.
Mg(2+) and Ca(2+) transport via OsHKT2;4 may be small and would depend on competing K(+) concentrations in plants.[OsHKT2;4] (Mus musculus) PubMed
8496.
The authors show that all four RAD51 paralogues act in DNA repair and recombination, though not equivalently, while mutation of only one RAD51 paralogue gene significantly impedes variant surface glycoprotein switching.[RAD51] (Mus musculus) PubMed
8497.
The expression patterns of miR-2b and P25 gene indicate that miR-2b might act as a fine-tuning regulator of expression of the P25 gene at the post-transcriptional level.[microRNA-2b] (Mus musculus) PubMed
8498.
It is shown that a member of the TetR family of transcriptional regulators (SACE_7040 homolog) is an important regulator of the morphological differentiation of Saccharopolyspora erythraea. (Mus musculus) PubMed
8499.
These data indicate that CDC15 regulates hyphal growth and asexual development for the pathogenic development of M. orzyae. [CDC15] (Mus musculus) PubMed
8500.
Wheat, barley, maize, and rice all possess purple acid phosphatase (PAP) genes that, expressed in Pichia pastoris, give fully functional phytases (PAPhys) with very similar enzyme kinetics.[PAP] (Mus musculus) PubMed
8501.
LTN1 is a crucial phosphate (Pi) starvation signaling component downstream of miR399 involved in the regulation of multiple Pi starvation responses in rice.[LTN1] (Mus musculus) PubMed
8502.
Cwht1p crystals were grown and subjected to X-ray irradiation, giving a complete diffraction dataset to 2.04 A resolution. [Cwht1p] (Mus musculus) PubMed
Findings support the notion of a central role for Puf2 in parasite latency during switch between the insect and mammalian hosts [Puf2]. (Mus musculus) PubMed
8505.
Csn2 is a ds-DNA-binding protein functioning at the quaternary structure level and regulated by Ca(2+) ions [Csn2] (Mus musculus) PubMed
8506.
The authors observed that beta-sheet and coiled-coil domains in the N-terminal moiety of SiiE are required for the control of SiiE retention on the surface and co-ordinated release.[SiiE] (Mus musculus) PubMed
8507.
Rice ATP binding cassette (ABC)-type transporter, ABCG43, is Cadmium inducible and confers cadmium tolerance on yeast. (Mus musculus) PubMed
8508.
Inactivation of pulA, a MalR regulated gene which encodes a cell surface carbohydrate binding protein, significantly reduced GAS human epithelial cell adhesion and mouse oropharyngeal.[pulA & MalR] (Mus musculus) PubMed
8509.
Both Fet31 and Fet34 localize to the yeast plasma membrane and both support iron uptake along with Ftr1 protein.[Fet31 & Fet34 & Ftr1] (Mus musculus) PubMed
8510.
aph(3")-IIIa was present in 22 strains of methicillin resistant staphylococcus aureus. [aph(3")-IIIa] (Mus musculus) PubMed
8511.
The authors show that postreplication repair (PRR) of newly synthesized DNA in UV-damaged yeast cells is inhibited in the absence of Mec1 and Rad53 proteins.[Mec1 and Rad53] (Mus musculus) PubMed
8512.
These data show that LSA-1 plays a critical role during late liver-stage schizogony and is thus important in the parasite transition from the liver to blood.[LSA-1] (Mus musculus) PubMed
8513.
The authors propose that CTL843 acts as a S-adenosylmethionine/S-adenosylhomocysteine transporter (SAMHT) allowing Chlamydia to acquire S-adenosylmethionine from the host cell and excrete the toxic by-product S-adenosylhomocysteine.[CTL843] (Mus musculus) PubMed
8514.
NanS, a carbohydrate esterase that is shown in this study to deacetylate the 9 position of 9-O-sialic acid. [NanS] (Mus musculus) PubMed
8515.
Quantitative RT-PCR revealed that transcription of the bursicon monomers, burs and pburs, steadily increases through the larval stages, peaks in the black pupa stage, and decreases to below detectable levels by 8 h after adult ecdysis.[bursicon] (Mus musculus) PubMed
8516.
A gene responsible for tolerance to boron (B) toxicity in rice (Oryza sativa), named BORON EXCESS TOLERANT1, was identified.[BET1] (Mus musculus) PubMed
8517.
ABL1 modulates abscissic acid (ABA) and auxin responses by directly regulating the ABA-responsive elements containing genes. (Mus musculus) PubMed
8518.
Role of four calcium transport proteins, encoded by nca-1, nca-2, nca-3, and cax, in maintaining intracellular calcium levels in Neurospora crassa (Mus musculus) PubMed
8519.
These experiments demonstrate that inhibition of SID1 expression in vivo reduces the virulence of Histoplasma capsulatum yeasts.[SID1] (Mus musculus) PubMed
8520.
The authors provide evidence that the beta' zipper, an evolutionarily conserved loop of the largest subunit of RNA polymerase core, interacts with promoter spacer, a DNA segment that separates the -10 and -35 promoter elements. (Mus musculus) PubMed
8521.
Nop8p may control the exosome function during pre-rRNA processing [Nop8p] (Mus musculus) PubMed
8522.
Lysine 99 contributes 2.79 and 2.6 kcal/mol to Lys and alpha-ketoglutarate binding, and 1.85 kcal/mol to binding NADH, respectively.[saccharopine dehydrogenase] (Mus musculus) PubMed
8523.
the nascent antizyme polypeptide OAZ1 is the relevant polyamine sensor that operates in cis to negatively regulate upstream ribosomal frameshifting on the polysomes, where its own mRNA is being translated [OAZ1] (Mus musculus) PubMed
8524.
Cdc15 functions as a coincidence detector of two essential cell cycle oscillators: the Polo kinase Cdc5 synthesis/degradation cycle and the Tem1 G-protein cycle [cdc15, Tem1, and Polo; strain 2303] (Mus musculus) PubMed
8525.
These results demonstrate that the amino acid at position 109 in NP enhances viral RNA synthesis and the pathogenicity of highly pathogenic avian influenza viruses.[NP] (Mus musculus) PubMed
8526.
The cysteine-rich protein (CRP) of potato virus M inhibited both local and systemic silencing, whereas the triple gene block protein 1 (TGBp1) showed suppressor activity only on systemic silencing.[CRP & TGBp1] (Mus musculus) PubMed
8527.
The observed reduced virus production in salivary glands could be reverted by repair of the frameshift mutation in MCK-2 protein. (Mus musculus) PubMed
8528.
The data support the conclusion that D10Deltagdha parasites are not experiencing enhanced oxidative stress and that GDHa function may not be the provision of NADP(H) for reductive reactions.[gdha] (Mus musculus) PubMed
8529.
This in vivo study validates Kaposi's sarcoma-associated herpesvirus miR-K12-11 as a functional ortholog of miR-155 in the context of hematopoiesis and suggests a novel mechanism by which KSHV miR-K12-11 induces splenic B-cell expansion. (Mus musculus) PubMed
8530.
The data demonstrates that Goa1p is required for mitochondrial functions, especially complex I activity, and, as a consequence, is critically important in maintaining nontoxic levels of reactive oxidant species (goa1). (Mus musculus) PubMed
8531.
The results suggest that Cdc20p and Cdh1p may be anaphase-promoting complex/cyclosome APC/C activators that are important for mitosis but also morphogenesis in C. albicans (Cdc20 and Cdh1). (Mus musculus) PubMed
8532.
Examination of the kinetic mechanisms of interactions of the strong DNA-binding subsite and the total DNA-binding site of the ASFV pol X with the ssDNA, and energetics of the intermediate formations (polymerase X). (Mus musculus) PubMed
8533.
Examination of the energetics of interactions of the total DNA-binding site and the strong DNA-binding subsite of the ASFV pol X with the ssDNA (polymerase X). (Mus musculus) PubMed
8534.
Data indicates that actin plays a major role in the orderly traffic and localization of CHS-1 at the hyphal apex (chitin synthase 1). (Mus musculus) PubMed
8535.
DYF-17 and DYF-18-cellular components important for cilium formation and function (Mus musculus) PubMed
8536.
The 147C strain of Helicobacter pylori expressing tyrosine-phosphorylated CagA (EPIYA present) induced enhanced MMP-9 secretion by gastric epithelial cells.[CagA] (Mus musculus) PubMed
8537.
Our results suggest the involvement of RNase G in the processing of the 5'-region of 23S rRNA precursors.[RNaseG] (Mus musculus) PubMed
8538.
Deletion of saeRS in Staphylococcus epidermidis resulted in an increase in biofilm-forming ability, which was associated with increased extracellular DNA release and up-regulated Aap expression.[saeRS] (Mus musculus) PubMed
8539.
MpkB MAP kinase is required for some post-karyogamy process as well as at the hyphal anastomosis stage to accomplish sexual development successfully. [MpkB MAP kinase] (Mus musculus) PubMed
8540.
These results demonstrate that, as in mitosis, Smc5-Smc6 is required to ensure proper chromosome segregation during meiosis.[Smc6, Smc5] (Mus musculus) PubMed
8541.
Inhibition of Cdc25 by the replication checkpoint is reinforced by degrading any Cdc25 which is not phosphrorylated and/or 14-3-3 bound.[Cdc25] (Mus musculus) PubMed
8542.
the impact of the F610A mutation on the functionality of AcrB by means of computational techniques [AcrB] (Mus musculus) PubMed
8543.
TFIIH constitutes a multitarget complex for Ydj1, as six of the seven TFIIH core components contain biologically relevant Ydj1- binding motives.[TFIIH, Ydj1] (Mus musculus) PubMed
8544.
The amino-terminal conserved, glutamate-rich sequence of herpesvirus saimiri Tip specifically interacts with the human retromer subunit Vps35 and inhibits retromer activity.[Tip] (Mus musculus) PubMed
8545.
These findings indicate that binding of NS1 to Scribble and Dlg1 functions to disrupt the cellular tight junction and that this effect likely contributes to the severe disease associated with highly pathogenic H5N1 influenza A viruses.[NS1] (Mus musculus) PubMed
8546.
Trypanosoma brucei RGG2, directly binds mRPN1 and is thought to modulate guide RNA utilization by editing complexes[mitochondrial RNA precursor-processing endonuclease 1] (Mus musculus) PubMed
8547.
graX, also involved in cationic antimicrobial peptide resistance and cotranscribed with graRS, encodes a regulatory cofactor of the GraSR signaling pathway.[GraS, GraR] (Mus musculus) PubMed
8548.
The stability and folding relaxation rate of phosphoglycerate kinase (PGK) Forster resonance energy transfer (FRET) constructs localized in the nucleus or in the endoplasmic reticulum (ER) of eukaryotic cells, was measured.[PGK] (Mus musculus) PubMed
8549.
Intrinsic HIV-2 integrase variation at "secondary" HIV-1 integrase inhibitor-resistance sites may affect the genetic barrier to HIV-2 INI resistance.[Integrase] (Mus musculus) PubMed
8550.
These data define the importance of a cluster of mutations in the second zinc finger of E6m in increasing the oncogenic potential of human papillomavirus 83.[E6] (Mus musculus) PubMed
8551.
Orexin A acts as feeding regulator in the zebrafish. (Mus musculus) PubMed
8552.
VopL stabilizes primarily lateral (short-pitch) contacts between actin monomers to create the base of a two-stranded filament. (Mus musculus) PubMed
8553.
VopL promotes rapid cycles of filament nucleation and detachment and stabilizes a hexameric double-stranded pointed end nucleus. (Mus musculus) PubMed
8554.
Here the ion and water molecules are queued by the KscA potassium channel during permeation; their modification is predicted under physiologically relevant conditions. (Mus musculus) PubMed
8555.
Data indicate that Spb4 is a component of early nucle(ol)ar pre-60S ribosomal particles containing 27SB pre-rRNA. [Spb4] (Mus musculus) PubMed
8556.
report that four subunits of the Ccr4-Not complex-Ccr4p, Pop2p, Not2p, and Not4p-severely impact HSP104 RNA transcription site-associated retention induced by MFT1 gene deletion[not4] (Mus musculus) PubMed
8557.
The interactions of Tom22, a multifunctional subunit of the outer membrane translocator TOM40 complex, with other translocator subunits, were analyzed.[Tom22] (Mus musculus) PubMed
8558.
LacY is oriented physiologically with a closed periplasmic side that limits access of sugar to the binding site.[LacY] (Mus musculus) PubMed
8559.
Rice DNG701 is a 5-meC DNA glycosylase/lyase responsible for the demethylation of Tos17.[DNG701] (Mus musculus) PubMed
structural and functional analyses reveal that the effector domain of AVR3a contains a conserved, positively charged patch and that this region, rather than the RXLR domain, is required for binding to phosphatidylinositol monophosphates[AVR3a] (Mus musculus) PubMed
8562.
RolR (ResorcinolRegulator) may represent a new subfamily of TetR proteins that are invovled in aromatic degradation and sharing common recognition mode as for RolR [RolR] (Mus musculus) PubMed
cell-free studies suggest that Mes1 behaves as a pseudosubstrate for Fzr1/Mfr1 but works as a competitive substrate for Slp1[Fzr1] (Mus musculus) PubMed
8565.
Interaction of WhcA with SpiA is modulated by the redox status of the cell. [WhcA] (Mus musculus) PubMed
8566.
katanin regulatory subunit in turn caused a dramatic change in the microtubule-binding properties of the N-terminal domain of the catalytic subunit[ katanin ] (Mus musculus) PubMed
8567.
EYE2 is positioned along, and adjacent to, the daughter four-membered rootlet in the absence of pigment granules[ EYE2 ] (Mus musculus) PubMed
8568.
Aerobic inactivation of catalytic hydrogen oxidation by the [NiFe]-hydrogenase (HoxEFUYH) is total and nearly instantaneous, producing two inactive states. [HoxEFUYH] (Mus musculus) PubMed
8569.
(trans-acyltransferase) The X-ray crystal structure of trans-acyltransferase (AT) from "AT-less" disorazole synthase (DSZS) is reported and a model is derived for the selective association of the DSZS AT and its acyl carrier protein substrate. (Mus musculus) PubMed
8570.
(H-NOX) Structure of the heme pocket of H-NOX family protein highlights the locations of important residues; overview of the distal and proximal pockets reveals hydrogen-bonding network, proximal His-102, and residues associated with heme deformation (Mus musculus) PubMed
8571.
These results showed that changing the glutamine to a basic arginine residue of Newcastle disease virus fusion protein reduced viral replication and attenuated the pathogenicity of the virus in chickens.[F] (Mus musculus) PubMed
8572.
Gene polymorphisms and copy number variation was observed in isolates of P. vivax from Southeast Asian countries. In Korean isolates polymorphism is limited to the F1076L variant, and no isolates with high level of resistance were found [pvmdr1;pvcrt-o] (Mus musculus) PubMed
8573.
These results clearly demonstrate that Sup35p C-terminal domain plays a critical role in prion propagation and provide new insights into the mechanism of prion conversion.[Sup35] (Mus musculus) PubMed
8574.
These findings suggest that Rho-ROCK signaling could be involved, via a mitochondrial pathway, in the apoptosis-like death of Cryptococcus neoformans induced by the adherence of Staphylococcus aureus.[Rho, Rho-associated coiled-coil forming kinase] (Mus musculus) PubMed
8575.
The essential role of lipoamide dehydrogenase (LipDH) in bloodstream parasites was confirmed by an in vivo model. Lipdh-/- cells were unable to infect mice.[lipoamide dehydrogenase] (Mus musculus) PubMed
8576.
Findings suggest that Orf5 are homologs of YscL from Yersinia. They associated with the bacterial membrane and interact with EscN. (Mus musculus) PubMed
8577.
first PARG crystal structure (derived from the bacterium Thermomonospora curvata), which reveals that the PARG catalytic domain is a distant member of the ubiquitous ADP-ribose-binding macrodomain family [PARG] (Mus musculus) PubMed
8578.
T2SS is required for V. vulnificus pathogenicity, which is mediated by at least two secreted factors, VvhA hemolysin and VvpE elastase, via facilitating the secretion and exposure of these factors to host cells. [VvhA, VvpE] (Mus musculus) PubMed
8579.
Stk, a serine/threonine protein kinase activates genes for virulence factors, osmoregulation, metabolism of alpha-glucans, and fatty acid biosynthesis, as well as genes affecting cell wall synthesis. [Stk] (Mus musculus) PubMed
8580.
The G(S)Z isozyme serves as an ATP phosphoribosyltransferase in histidine biosynthesis when histidine is available; however, HisG(L) also functions as ATP phosphoribosyltransferase, particularly during nitrogen fixation (HisG(L)and HisG(S)Z). (Mus musculus) PubMed
8581.
MASP52 (mucin-associated surface protein) plays a role in a process whereby the trypomastigote forms of the parasite invade the host. [MASP52] (Mus musculus) PubMed
8582.
The authors discovered that Helicobacter pylori strains establish bacterial colonies deep in the gastric glands and identified a novel protein, ChePep, necessary to colonize this niche.[ChePep] (Mus musculus) PubMed
8583.
Data found IolR to be required for the repression of its own gene and for the downregulation of the idhA-encoded myo-inositol dehydrogenase activity in the presence and absence of inositol. [IolR] (Mus musculus) PubMed
8584.
ASP is effectively expressed from the 3' LTR in infected T cells and localizes to the cell membrane. [Asp] (Mus musculus) PubMed
8585.
MsmK was identified as an ATPase which energizes multiple carbohydrate transporters in S. pneumoniae [MsmK]. (Mus musculus) PubMed
8586.
our study suggests that RIP1 has emerged as a molecular switch in triggering cell death or survival in Branchiostoma (Mus musculus) PubMed
8587.
results demonstrate that phosphodiesterase SmNPP-5 is a virulence factor for schistosomes [SmNPP-5] (Mus musculus) PubMed
8588.
Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL mRNA expression. [RANKL] (Mus musculus) PubMed
8589.
Among the residues studied, F270 and Q498 are critical specificity determinants for the distinction of mono- from dicarboxylates, and N501 is a critical residue for transport.[Jen1] (Mus musculus) PubMed
8590.
Transcriptional activation of maize defence genes in infections with Deltapit1/2 mutant strains indicates that the mutants have a defect in suppressing plant immune responses.[pit1 & pit2] (Mus musculus) PubMed
8591.
Agr-dependent repression of staphylococcal superantigen-like proteins expression is indirect and mediated by the transcription factor repressor of toxins (Rot).[Rot] (Mus musculus) PubMed
8592.
BraDE is involved in bacitracin sensing and signalling through BraSR, whereas VraDE acts specifically as a detoxification module and is sufficient to confer bacitracin and nisin resistance.[BraSR, BraDE, VraDE] (Mus musculus) PubMed
8593.
These data indicate that nuclear shuttling is critical for Ssd1 mRNA binding and Ssd1-mRNA localization in the cytoplasm.[Ssd1] (Mus musculus) PubMed
A new 80 kDa protein, Bombyx mori egg protein 80 (BmEP80) is a component of the eggshell which is secreted by follicle cells during the late vitellogenesis stage to early choriogenesis stage. (Mus musculus) PubMed
8596.
M18BP1 directly binds CENP-C through conserved domains in the CENP-C protein (M18BP1) (Mus musculus) PubMed
8597.
The phenotype of temperature-sensitive (ts) mutants of GTF1, a gene proposed to code for subunit F of mitochondrial amidotransferase in Saccharomyces cerevisiae, is described.[Gtf1p] (Mus musculus) PubMed
8598.
Polzeta and Rev1 are unique among PCNA-interacting proteins in using the novel binding site near the intermolecular interface of PCNA.[PCNA, Polzeta, Rev1] (Mus musculus) PubMed
8599.
The present findings provide new insights on how MA interacts with CaM that may ultimately help in identification of the functional role of CaM-Gag interactions in the HIV replication cycle.[Matrix protein] (Mus musculus) PubMed
8600.
In the absence of SPI-2 protein, ectromelia virus is attenuated in mousepox-susceptible mice, resulting in lower viral loads in the liver, decreased spleen pathology, and substantially improved host survival.[SPI-2] (Mus musculus) PubMed
8601.
Caenorhabditis elegans SNAP-29 is required for organellar integrity of the endomembrane system and general exocytosis in intestinal epithelial cells. (Mus musculus) PubMed
8602.
Results identify three adiponectin receptor homologs in C. elegans, paqr-1, -2 and -3, and suggest that paqr-1 and paqr-2 regulate fatty acid metabolism and cold adaptation [paqr-1, -2, -3]. (Mus musculus) PubMed
8603.
The role of CagA dimerization in induction of the hummingbird phenotype, was investigated.[CagA] (Mus musculus) PubMed
8604.
Genetic deletion of ptpA or ptpB does not affect in vitro growth or cell wall integrity, raising the possibility that PtpA and PtpB have specialized functions during infection.[PtpA & PtpB] (Mus musculus) PubMed
8605.
These data reveal a novel mechanism for the inhibition of hepatitis B virus replication by cIAP2 via acceleration of the ubiquitin-proteasome-mediated decay of polymerase.[polymerase] (Mus musculus) PubMed
8606.
HTLV-1 accessory protein p13 binds the SH3 domain of Src family kinases via its carboxyl-terminal proline-rich motif, forming a stable heterodimer that translocates to mitochondria. (Mus musculus) PubMed
8607.
E. coli O157 : H7-derived flagellin induces rapid phosphorylation of the epidermal growth factor receptor, as an early event in intestinal epithelial cell signalling, and that this is required for the release of the pro-inflammatory cytokine IL-8.[fliC] (Mus musculus) PubMed
8608.
Each subunit deletion resulted in a reduction in the adhesion to intestinal cells to the same level of laboratory strains, and this effect was restored by complementary plasmids, suggesting that the 4 proteins are necessary for CS6 expression.[CS6] (Mus musculus) PubMed
8609.
These data define PceT (and more generally the new RdhT family) as a class of TF-like chaperones involved in the maturation of proteins secreted by the twin-arginine translocation pathway.[PceT] (Mus musculus) PubMed
8610.
Data reveal that Xog1p, originally identified from LL-37 binding, has a role in C. albicans adhesion to polystyrene and, by inference, attach to host cells via direct or indirect manners [Xog1p]. (Mus musculus) PubMed
8611.
Schizosaccharomyces pombe mcb1(+) (Mcm-binding protein 1), an apparent orthologue of the human MCM-binding protein that associates with a subset of MCM complex proteins.[MCM-BP] (Mus musculus) PubMed
8612.
Rab11 functions are mediated by evolutionarily conserved and potentially lineage-specific interactions essential for the integration of the endomembrane system. [Rab11] (Mus musculus) PubMed
8613.
Glycerol 3-phosphate, which is produced in vivo by a glycosome-resident glycerol kinase, mitigated acid inactivation of lysate-derived TbHK activity.[TbHK1] (Mus musculus) PubMed
8614.
Depletion of the major 5'-3' exoribonuclease, XRNA, resulted in the stabilization of most mRNAs with half-lives under 30 min[5'-3' exoribonuclease ] (Mus musculus) PubMed
8615.
Bombyx mori flap endonuclease-1 (BmFEN-1) gene consists of seven introns and eight exons that encode a protein with 380 amino acids that has the typical XPG domain. BmFEN-1 can inhibit apoptosis and promote cell proliferation. (Mus musculus) PubMed
8616.
PIC5 is a novel virulence factor involved in appressorium differentiation and pathogenesis in Magnaporthe oryzae. [PIC5] (Mus musculus) PubMed
8617.
We observed mutations in vraS and graR during vancomycin non-susceptibility development and novel stop codons in the reverted strain. Mutations in graR appear important for development of intermediate susceptibility to vancomycin. [VraSm GraR] (Mus musculus) PubMed
8618.
Increaased (E)-beta-caryophyllene synthase gene activity in Zea mays roots upon feeding by larvae of Diabrotica virgifera virgifera [TPS 23] (Mus musculus) PubMed
8619.
NAR2.1 was mainly expressed in roots and induced by nitrate. NAR2.1 plays a key role in enabling the plant to cope with variable nitrate supply. [NAR2.1] (Mus musculus) PubMed
8620.
The interaction between the human NimA-like protein kinase Nek9 and the Helicobacter HcpC has been validated by ELISA and surface plasmon resonance. (Mus musculus) PubMed
8621.
Detailed characterization of a functionally unknown gene (HP986), which was detected in patient isolates, is reported.[HP986] (Mus musculus) PubMed
8622.
the structural and functional features of mutant GGBP [GGBP] (Mus musculus) PubMed
8623.
Glycosylation of the CH2/CH3 interface inhibits interaction with the pathogen IgA binding protein SSL7, while maintaining binding of pIgR, essential to the biosynthesis and transport of SIgA.[SSL7] (Mus musculus) PubMed
8624.
The crystal structure of EF1143 and dynamic light scattering measurements in solution revealed a tetrameric oligomer as the most probable biologically active unit.[EF1143] (Mus musculus) PubMed
8625.
(H2A.Z) The role of H2A.Z is to facilitate addition and removal of promoter nucleosomes and to prevent formation of unfavorable stable epigenetic chromatin structures. (Mus musculus) PubMed
8626.
Repression was also more efficient when Pab1p was bound in close proximity to Puf5p.[Puf5p, Pab1p] (Mus musculus) PubMed
8627.
CIITA inhibit Tax-2 by binding the viral transactivator both directly or through a tripartite interaction with NF-YB in.[Tax-2] (Mus musculus) PubMed
8628.
[cytidine repressor CytR] Operator-DNA binding of CytR is accompanied by disorder-to-order transition in which the disordered state is an ensemble of distinct conformations. (Mus musculus) PubMed
8629.
The plant-specific N-terminal domain of CK2beta subunits is involved in the down-regulation of the CK2 holoenzyme activity and in the stabilization of CK2beta1 protein.[CK2beta1] (Mus musculus) PubMed
8630.
a novel signaling pathway was found by which Cdc28 controls Cbk1 through the regulatory phosphorylation of Mob2, which is crucial for normal hyphal development.[Cdc28] [Cbk1] [Mob2] (Mus musculus) PubMed
8631.
Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1. [Mrr1] (Mus musculus) PubMed
8632.
The flagellar localization and membrane association of FCaBP in L. amazonensis suggest that the mechanisms for flagellar targeting, including a specific palmitoyl acyltransferase, are conserved in this organism.[FCaBP] (Mus musculus) PubMed
8633.
A carbohydrate binding site within GspBBR mediates binding of S. gordonii strain M99 to sialyl-T antigen, and this interaction is important for virulence. (Mus musculus) PubMed
8634.
From these results, the authors speculate that the Na(+) flux is reduced by the PomB-F22Y mutation, and that PomB-F22 is important for the effective release of Na(+) from PomB-D24.[PomB] (Mus musculus) PubMed
8635.
The association between the emergence of influenza A/H1N1/09v 222G/N polymorphisms in the hemagglutinin gene and increased virulence was documented. (Mus musculus) PubMed
8636.
Adherence assays revealed significantly reduced binding of the Deltarga mutant to epithelial HEp-2 cells and to immobilized human keratin 4, respectively.[Rga] (Mus musculus) PubMed
8637.
Pneumococcal choline-binding protein A (PcpA) plays a critical role in pneumococcal pneumonia. [PcpA] (Mus musculus) PubMed
8638.
SWI/SNF acts at least in part independently of SOMI-1 to inhibit the supernumerary molt. ; somi-1 coordinates a nuclear response that complements the activity of mir-84 [SWI/SNF; and mir-84] (Mus musculus) PubMed
8639.
a ternary crystal complex structure of Escherichia coli Hfq bound to a major Hfq recognition region on DsrA (AU(6)A) together with ADP, and a crystal complex structure of Hfq bound to ADP [Hfq and DsrA; strain not specified] (Mus musculus) PubMed
8640.
Rrn3 crystal structure reveals a unique HEAT repeat fold and a surface serine patch [Rrn3] (Mus musculus) PubMed
8641.
Leaf rust resistance and powdery mildew resistance co-locate with Sr2. [Sr2] (Mus musculus) PubMed
8642.
These data show that the A domains of CTRP are critical for ookinete gliding motility and oocyst formation whilst, unexpectedly, its tandem thrombospondin type I repeat-like domains are fully redundant.[CTRP] (Mus musculus) PubMed
8643.
A genetic and functional interaction between the innexin UNC-7 and the cation leak channel NCA in Caenorhabditis elegans neurons, is reported.[UNC-7, NCA] (Mus musculus) PubMed
8644.
protein 7 modifies TGEV virulence, reducing virus pathology and increasing the period of virus shedding.[protein 7] (Mus musculus) PubMed
8645.
findings indicate that the amino acid at position 100 of VP1 is important for EMCV in vivo infection, and its mutation alters the pathogenicity of viral infection in mice [VP1] (Mus musculus) PubMed
8646.
S. Typhi trans-complemented with the functional sopD2 gene from S. Typhimurium (sopD2STM) reduced the invasion of human epithelial cell lines (sopD2). (Mus musculus) PubMed
8647.
Hyperosmotic stress destroyed the structure of ocular surface epithelium, induced the decrease of conjunctival goblet cell density and MUC5AC expression, and led to decreased tear film stability. [MUC5AC] (Mus musculus) PubMed
8648.
Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression. (Mus musculus) PubMed
8649.
conformational coupling between the nucleotide-binding domain and the transmembrane domain in the Escherichia coli maltose transporter [maltose transporter] (Mus musculus) PubMed
8650.
found that over-expression of the yGPN1 gene promotes sister chromatid separation during anaphase[GPN1] (Mus musculus) PubMed
8651.
Sucrose non-fermenting1-related protein kinase 2 (SnRK2) plays a critical role in plant sugar signaling via phosphorylation.[SnRK2] (Mus musculus) PubMed
8652.
Both Vibriocholerae FadR and Escherichia coli FadR bound the Vibrio cholerae plsB promoter region and binding was reversed upon addition of long-chain fatty acyl-CoA thioesters.[FadR & PlsB] (Mus musculus) PubMed
8653.
Chlamydia protease-like activity factor (CPAF) targets chlamydial effectors secreted early during the establishment of the pathogen-containing vacuole [CPAF] (Mus musculus) PubMed
8654.
Hemoglobin prevented expression of the agr quorum sensing system. (Mus musculus) PubMed
8655.
findings show that the SaPI1-encoded protein gp6 is necessary for efficient formation of small capsids; suggests gp6 acts as an internal scaffolding protein in capsid size determination.[gp6 protein] (Mus musculus) PubMed
8656.
Taken collectively, the results provide evidence that AspA is a biofilm-associated adhesin that may function in host colonization by Streptococcus pyogenes.[AspA] (Mus musculus) PubMed
8657.
The SNP on exon 10 of the Wx gene, from C -> T, is a significant factor influencing gel consistency. [Waxy] (Mus musculus) PubMed
8658.
conserved Mediator protein Ssn8 functions as a global regulator which negatively regulates diverse physiological and developmental processes and is required for virulence in C. neoformans [Ssn8] (Mus musculus) PubMed
8659.
a high level of allelic diversity, 27 polymorphic nucleotides and 33 amino acid haplotypes of the Duffy Binding Protein II (DBPII) gene in 100 local Plasmodium vivax isolates collected from two hypoendemic areas (Mus musculus) PubMed
8660.
Dimerization is required for and driven by receptor engagement of the Duffy binding protein (DBP). (Mus musculus) PubMed
8661.
Using C-terminal fusion to Suc2-His4, the authors determined the orientation of full-length Arv1 in the endoplasmic reticulum membrane.[Avr1] (Mus musculus) PubMed
8662.
Residue Phe-191 of B. subtilis UDG is critical for the interaction with phi29 p56 proteins. [p56] (Mus musculus) PubMed
8663.
Identical domains of Vps23 are required for both Rim and ESCRT pathways, but the UEV domain was shown to bind the arrestin-like protein Rim8/PalF in the Rim pathway, whereas it binds Vps27 in the ESCRT pathway.[Vps23 & Rim8 & Vps27] (Mus musculus) PubMed
8664.
The thk1 mutation defines a negative regulator that functions downstream of dek1 in the signaling system that controls aleurone specification and other aspects of endosperm development.[Thk1] (Mus musculus) PubMed
8665.
Hrf1 conferred enhanced tolerance to drought stress on transgenic crops.[Hrf1] (Mus musculus) PubMed
8666.
These results indicate that transcription of enterohemolysin (ehx) is positively regulated by Ler, GrlA, and LrhA, which all act as positive regulators for locus of enterocyte (LEE) expression.[ehx; LEE] (Mus musculus) PubMed
8667.
This study compared the capacities of different espF alleles to inhibit bacterial phagocytosis by macrophages, translocation through an M-cell coculture system, and uptake by and translocation through cultured bovine epithelial cells.[EspF] (Mus musculus) PubMed
8668.
The authors showed that AgrA is indispensable to agr P2 and P3 transcription, whereas SarA activates and SarR represses P2 transcription in the Agr locus. (Mus musculus) PubMed
8669.
Gtf2 and its homologs GtfA and GtfB possess the conserved molecular chaperone activity that mediates protein glycosylation of bacterial adhesins [Gtf2, GtfA, GtfB] (Mus musculus) PubMed
8670.
The conformational states of Escherichia coli Rep helicase undergoing ATP hydrolysis while bound to a partial-duplex DNA (pdDNA) were studied using single-molecule fluorescence resonance energy transfer.[Rep] (Mus musculus) PubMed
8671.
This work defines two MntR-regulated new proteins, MntS and MntP, involved in manganese homeostasis and suggests mechanisms for their action.[MntS and MntP] (Mus musculus) PubMed
8672.
This study characterized glycosylphosphatidylinositol-anchored micronemal antigen (GAMA) encoded by the PF08_0008 gene in Plasmodium falciparum.[GAMA] (Mus musculus) PubMed
8673.
expression pattern of endogenous Apo-14 in zebrafish embryogenesis [Apo-14] (Mus musculus) PubMed
8674.
gene and protein structures of the C. elegans filamin orthologs fln-1 and fln-2 [FLN-1][FLN-2] (Mus musculus) PubMed
8675.
peel-1 encodes a novel four-pass transmembrane protein that is expressed in sperm and delivered to the embryo via specialized, sperm-specific vesicles. [peel-1] (Mus musculus) PubMed
8676.
CyaY does not alter the relative ratio between [2Fe2S](2+) and [4Fe4S](2+) but directly affects enzymatic activity [CyaY][IscU] (Mus musculus) PubMed
8677.
zinc regulates Zap1 activity post-translationally via three independent mechanisms [Zap1] (Mus musculus) PubMed
8678.
pORF3 increases HNF4 phosphorylation through the ERK and Akt kinases [OFR3] (Mus musculus) PubMed
8679.
a restricted terminal region of the chromosome is specifically dedicated to the last steps of chromosome segregation and to their coupling with cell division by FtsK [FtsK] (Mus musculus) PubMed
8680.
O-acetylserine sulfhydrylase has predominantly entropy driven methionine binding is not mediated through classical hydrophobic binding, instead, may involve desolvation of the polar active site. (Mus musculus) PubMed
8681.
levels of transcription of pfhrp2 and pfhrp3, and protein expression of PfHRP varied between different P. falciparum strains [pfhrp2][pfhrp3] (Mus musculus) PubMed
8682.
Quantification of the in vivo Ni(2+)-NikR response of 11 direct NikR targets that encode functions related to nickel metabolism, four activated and seven repressed genes (NikR). (Mus musculus) PubMed
8683.
[metallo-beta-lactamase IMP-1] Steady-state kinetic and spectroscopic studies suggest that metal binding to metal-free metallo-beta-lactamase (IMP-1) follows a positive-cooperative mode. (Mus musculus) PubMed
8684.
The membrane topology of the cyanobacterial bicarbonate transporter, SbtA, was determined.[SbtA] (Mus musculus) PubMed
8685.
tfoY is required for efficient transformation in V. fischeri, but is not functionally identical to tfoX. [tfoY] (Mus musculus) PubMed
8686.
[uridine phosphorylase UPP] The reaction mechanism of uridine phosphorylase from T. cruzi is defined by steady-state and pre-steady-state kinetics, pH-rate profiles, kinetic isotope effects from uridine, and solvent deuterium isotope effects. (Mus musculus) PubMed
8687.
Expression of auxin-related genes was affected in oni1 shoot.[Oni1] (Mus musculus) PubMed
8688.
Evidence for a mechanism of intrachromosomal gene duplication where the GSH1 locus becomes polyploid preserving two intact copies of the essential gene upon sequential rounds of gene inactivation (GSH1). (Mus musculus) PubMed
8689.
function in tick salivary gland may include inactivation of the salivation signal via sulfonation of dopamine or octopamine[SULT1 and Sult2] (Mus musculus) PubMed
8690.
Lgt processing of lipoproteins is required for lipoprotein mediated innate immune activation.[Lgt] (Mus musculus) PubMed
8691.
Modelling studies showed that the most functionality-lowering substitutions in OSC deeply alter the H-bond network involving the channel/constriction apparatus.[OSC] (Mus musculus) PubMed
8692.
The sequence of nine al-2 mutant alleles, was determined and the carotenoid content in the corresponding strains, was analyzed.[al-2] (Mus musculus) PubMed
8693.
A detailed biochemical analysis of NTPase/RNA helicase and 5'-RNA phosphatase activities of recombinant CHIKV-nsP2T protein was carried out.[nsP2] (Mus musculus) PubMed
8694.
This study suggested that the constitutive expression of ramA locus regulate not only multidrug efflux pump and accessory genes but also genes involved in carbon metabolic pathways. (Mus musculus) PubMed
8695.
global gene expression profile in stem bases of crl1 mutant and wild-type (WT) plants [CRL1] (Mus musculus) PubMed
8696.
The synergistic increase is caused by the Ca(2+) influx from the extracellular medium via the Cch1-Yam8 complex.[Cch1, Yam8] (Mus musculus) PubMed
8697.
Asp-208 is directly involved in proton motive force-driven protein export and that the cooperative interactions of FlhA with FlhB, FliH, FliI, and FliR drive the translocation of export substrate.[FlhA] (Mus musculus) PubMed
8698.
The key role MtFTa1 plays in regulating flowering was demonstrated by the identification of fta1 mutants that flowered significantly later in all conditions examined.[MtFTa1] (Mus musculus) PubMed
8699.
ROP18 phosphorylates and inactivates immunity-related GTPases , thereby protecting the parasite from killing.[Review][ROP18] (Mus musculus) PubMed
8700.
These results suggest that Yfr017p functions as an inhibitor of Gdb1p, enhancing the ability of yeast cells to store glucose as glycogen.[Gdb1 & Yfr017] (Mus musculus) PubMed
8701.
The influence of the lipid environment on p7 ion channel structure and function, was analyzed.[p7] (Mus musculus) PubMed
8702.
The data support an orientation of the CitS and GltS monomers in the dimer with the N-termini close to the dimer interface.[GltS] (Mus musculus) PubMed
8703.
The residue at the H5 helix position of the aromatic/arginine filter of both OsLsi1 and AtNIP5;1 plays a key role in the permeability to silicon and boron, but there is a relatively low selectivity for arsenite.[OsNIP2;1] (Mus musculus) PubMed
8704.
Molecular-dynamics simulations of the bacterial multidrug ATP-binding cassette transporter Sav1866, is reported.[Sav1866] (Mus musculus) PubMed
8705.
The search process is governed by the interaction between the virus and the LamB receptors, and by the spatial organization of the receptor network on the cell surface.[LamB] (Mus musculus) PubMed
8706.
The effect of an inert small molecule osmolyte, trimethyl amine N-oxide (TMAO), upon the conformational equilibria of Escherichia coli adenylate kinase was studied using time-resolved fluorescence resonance energy transfer.[Adenylate kinase] (Mus musculus) PubMed
8707.
data demonstrate that Puf2 is a key player in regulating sporozoite developmental control, and imply that transformation of salivary gland-resident sporozoites into liver stage-like parasites is regulated by a post-transcriptional mechanism [Puf2] (Mus musculus) PubMed
8708.
The relationships among LuxO, LuxR, and the small regulatory RNA qrr4 in the model quorum-sensing bacterium Vibrio harveyi, were investigated.[LuxO, LuxR, Qrr4] (Mus musculus) PubMed
8709.
TgNF3 protein is predominantly a nucleolar, chromatin-associated protein that binds specifically to T. gondii gene promoters in vivo, leading to a direct role in transcriptional regulation. [TgNF3] (Mus musculus) PubMed
8710.
The authors used site-directed mutagenesis and azide rescue activity assays to show definitively that the catalytic base in Thermobifida fusca Cel48A is aspartic acid 225.[Cel48A] (Mus musculus) PubMed
8711.
Data demonstrate that H. pylori HSP60/mAbs could modulate helicobacterial pathogenesis by increasing IL-8 and TNF-alpha production [Hsp60]. (Mus musculus) PubMed
8712.
NorG positively regulated the transcription of global regulators mgrA, arlS, and sarZ. [NorG] (Mus musculus) PubMed
8713.
A conjugation assay demonstrated cotransfer of tcrB (transferable copper resistance) and erm(B) genes between E. faecium and E. faecalis strains isolated from feces of piglets those were fed with copper supplemented diets. [tcrB] (Mus musculus) PubMed
8714.
The level of AdpA directly affects expression of developmental genes. [AdpA ] (Mus musculus) PubMed
8715.
holocytochrome c production by Saccharomyces cerevisiae HCCS [HCCS] (Mus musculus) PubMed
8716.
Transient-expression assays revealed the colocalization of the plant histone H3 and nuclear shuttle protein (NSP) in the nucleus and nucleolus and of histone H3 and movement proteins in the cell periphery and plasmodesmata.[NSP] (Mus musculus) PubMed
8717.
The authors demonstrate that the RNA-binding activity of NP is necessary for stabilization of cRNA, whereas, surprisingly, homo-oligomerization of NP is not essential.[NP] (Mus musculus) PubMed
8718.
Transfection of the SVGA astrocyte cell line with a plasmid encoding gp120 resulted in a time-dependent increase in expression levels of CCL5 in terms of mRNA and protein by 24.6 +/- 2.67- and 35.2 +/- 6.1-fold, respectively. [gp120] (Mus musculus) PubMed
8719.
ShanDong-Satellite RNAs reduced the accumulation of the 2b protein and its coding RNA4A and attenuated the yellowing caused by ShanDong strain, Cucumber mosaic virus (SD-CMV)infection.[2b protein] (Mus musculus) PubMed
8720.
Expression of DR0171 increased in response to gamma radiation. Inactivation of dr0171 increases the susceptibility of D. radiodurans cells to DNA-damaging agents. [DR0171] (Mus musculus) PubMed
8721.
Cyclic di-GMP and quorum sensing control the expression of vpsT and aphA. [vpsT] (Mus musculus) PubMed
8722.
A conjugation assay demonstrated cotransfer of tcrB (transferable copper resistance) and erm(B) genes between E. faecium and E. faecalis strains isolated from feces of piglets those were fed with copper supplemented diets. [tcrB] (Mus musculus) PubMed
8723.
OsSFR6 can act as a functional orthologue of AtSFR6 in the acquisition of freezing tolerance in Arabidopsis. [SFR6] (Mus musculus) PubMed
8724.
Rpa43 directly bind Spt5, an RNAPI elongation factor also acting in RNAPII-dependent transcription, and may also interact with the nucleosomal chaperone Spt6 [Rpa43] (Mus musculus) PubMed
8725.
H2BK123ub is removed by the deubiquitinases Ubp8 and Ubp10, but their genomic target regions remain to be determined [Ubp8, Ubp10, H2BK123; no strain indicated] (Mus musculus) PubMed
8726.
mechanistically similar functions of H2B ubiquitylation (nucleosome assembly) elicit different functional outcomes on genes depending on its positional context in promoters (repressive) versus transcribed regions (activating) [strain not found; H2B] (Mus musculus) PubMed
8727.
Parasites in which TbbetaHBDH (beta-hydroxybutyrate dehydrogenase) is depleted exhibit slowed growth, indicating an important role for this enzyme in vivo.[beta-hydroxybutyrate dehydrogenase] (Mus musculus) PubMed
8728.
CYP71Z6 & 7 appear to have evolved distinct roles in rice diterpenoid metabolism [CYP71Z6][CYP71Z7] (Mus musculus) PubMed
8729.
transcription of pacC is modulated in response to alternative RNA splicing of the palB gene [pacC][palB] (Mus musculus) PubMed
8730.
Rpa43 directly bind Spt5, an RNAPI elongation factor also acting in RNAPII-dependent transcription, and may also interact with the nucleosomal chaperone Spt6 [Rpa43] (Mus musculus) PubMed
8731.
AgsA fibrils may represent a distinctive type of structural and functional form of small heat shock protein from spherical oligomers [AgsA] (Mus musculus) PubMed
8732.
CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication [p97] (Mus musculus) PubMed
8733.
UreB facilitates the interaction of urease with accessory proteins during metallocenter assembly, with the N-terminal hinge and tether region being specifically required for this process. [UreB] (Mus musculus) PubMed
8734.
structural differences between SrtA and SrtC1 [SrtA][SrtC1] (Mus musculus) PubMed
8735.
The study used high-resolution optical tweezers to characterize the folding and unfolding reactions of a single GCN4 coiled coil domain and their dependence on the pulling direction. [GCN4] (Mus musculus) PubMed
8736.
the existence of a relationship between tubulins and P450 cytochromes during A. gambiae immune response to P. berghei invasion [cytochrome P450 reductase] (Mus musculus) PubMed
8737.
analysis of substrate specificity of TbSLS1, an inositol phosphorylceramide (IPC) synthase, and TbSLS4, a bifunctional sphingomyelin (SM)/ethanolamine phosphorylceramide (EPC) synthase [TbSLS1, TbSLS4] (Mus musculus) PubMed
8738.
ATPase p529 of Acidianus two-tailed virus associates with the Sulfolobus solute binding protein Sso1273. [p529] (Mus musculus) PubMed
8739.
[IscU] IscU is conformationally flexible and may allow for formation of iron-sulfur (FeS) complexes having different coordination patterns and binding stabilities as evidenced by differences in ability to transfer iron-sulfur clusters to apo-ferredoxin. (Mus musculus) PubMed
8740.
A T. brucei GNA1 conditional null mutant was shown to be unable to sustain growth in vitro under nonpermissive conditions, demonstrating that there are no metabolic or nutritional routes to UDP-GlcNAc other than via GlcNAc-6-phosphate. [GNA1] (Mus musculus) PubMed
8741.
The effects of the polymorphisms of the follicle-stimulating hormone receptor (FSHR) gene on egg production in a Beijing You chicken population divergently selected for egg number, egg weight, and BW across 3 generations are reported.[FSHR] (Mus musculus) PubMed
8742.
[U1 snRNP ribozyme] In contrast to most large and small ribozymes, the HDV ribozyme modeled in this review facilitates nucleophile RNA deprotonation and stabilizes conformation of the magnesium-dependent active site for in-line nucleophile attack. (Mus musculus) PubMed
8743.
This study examined the frequency of Plasmodium falciparum chloroquine transporter (pfcrt) haplotypes in Sri Lanka in 1996-1998 and 2004-2006 using a high-resolution melting assay.[pfcrt] (Mus musculus) PubMed
8744.
These results clarify recombination-mediated routes of cagA evolution and provide a solid basis for a deeper understanding of its function in pathogenesis.[cagA] (Mus musculus) PubMed
8745.
This study describes the conformational changes of SecB upon binding of all-Ala-bovine pancreatic trypsin inhibitor to spin-labeled single cysteine mutants of SecB. [SecB] (Mus musculus) PubMed
8746.
Among the identified HdeA client proteins, the periplasmic chaperones DegP and SurA were initially found to be protected by HdeA at a low pH, but they subsequently facilitated the HdeA-mediated acid recovery of other client proteins.[HdeA] (Mus musculus) PubMed
8747.
FRQ-bound CK1a progressively phosphorylates the positively charged N-terminal domain of FRQ at up to 46 nonconsensus sites, triggering a conformational change [FRQ] (Mus musculus) PubMed
8748.
we identified a protein homologous to a mammalian solute carrier family 4 (SLC4) bicarbonate transporter that we show is involved in valproic acid uptake. [SLC4] (Mus musculus) PubMed
8749.
Ypd1 is required for the viability of Cryptococcus neoformans via the Hog1 mitogen-activated protein kinase (MAPK) pathway but plays multiple cellular roles in both a Hog1-dependent and -independent manner. [Ypd1] (Mus musculus) PubMed
8750.
Suggest ammonia excretion via Rhcg1 in larval zebrafish gills is linked to sodium uptake via NHE3b. (Mus musculus) PubMed
8751.
Comparison of the native enzyme responses with those of a mutant allowed identification of the elementary steps that makes the mutant type more efficient than the wild type. [quinoprotein glucose dehydrogenase] (Mus musculus) PubMed
8752.
Our studies identify the role of AidB in alkylating agent exposed cells and suggest a new cellular strategy in which a subset of the genome is preferentially protected from damage by alkylating agents. (Mus musculus) PubMed
8753.
Intrinsic multiple functions of gene product 5 are shown to be served in turn regulated by gradual change of interdomain interactions, which enables the initial infection process with single protein trimer by continuous screw motion. [gene product 5] (Mus musculus) PubMed
8754.
Host temperature adaptation is accompanied by transient induction of the endoplasmic reticulum stress response and Ccr4-dependent posttranscriptional gene regulation contributes to resolution of ER stress during host temperature adaptation. [CCR4] (Mus musculus) PubMed
8755.
SDF-1 apparently acts through the adenylyl cyclase ACG to activate the cyclic AMP-dependent protein kinase A and trigger the production of more SDF-1. [SDF-1] (Mus musculus) PubMed
8756.
Putrescine is required for the expression of eif-5a. [eif-5a] (Mus musculus) PubMed
8757.
Our data suggest that Hsl7 may regulate cell cycle progression, while both Smu1 and Cla4 appear to be involved in the filamentous response in U. maydis. [Hsl7] (Mus musculus) PubMed
8758.
A novel phenylacetic acid-induced CoA-ligase encoding gene, designated as phlC, has been cloned from penicillin-producing fungus Penicillium chrysogenum. [phlC] (Mus musculus) PubMed
8759.
Exposure to arsenic downregulates EAAT1/GLAST activity and expression by a mechanism that involves several protein kinases, particularly p38 mitogen-activated protein kinase. (Mus musculus) PubMed
8760.
Shq1p operates as a Cbf5p chaperone during RNP assembly by acting as an RNA placeholder, thereby preventing Cbf5p from nonspecific RNA binding before association with an H/ACA RNA and the other core RNP proteins [strain not noted; SHQ1] (Mus musculus) PubMed
8761.
The study reports comparison of the cleavage efficiencies of all known hepatitis C virus NS3-4A protease cleavage sequences in a cell-based system. [NS3-4A protease] (Mus musculus) PubMed
8762.
Our results indicate that TbISWI is a versatile chromatin remodeler that regulates transcription at multiple Pol I loci and is particularly abundant at many Pol II transcription boundaries in T. brucei. [TbISWI] (Mus musculus) PubMed
8763.
Disclosed is the critical role of a specialized glutathione S-transferase (GST), GliG, which mediates carbon-sulfur bond formation in gliotoxin biosynthesis. [glutathione S-transferase] (Mus musculus) PubMed
8764.
An insertional mutation into the Ler linker region diminished oligomerization activity.[Ler] (Mus musculus) PubMed
8765.
The crystal structure of PDH from Streptococcus mutans in a complex with NAD(+) shows that the enzyme exists as a homo-dimer.[PDH] (Mus musculus) PubMed
8766.
The two consecutive glutamates in the beta4/alpha4 loop of T. maritima CheB that is absent in T. maritima CheY and in E. coli/S. typhimurium CheB may be one factor contributing to the low CheA affinity.[CheA, CheB] (Mus musculus) PubMed
8767.
Cationic lipids enhanced the assembly of FtsZ in association with an increase in the GTPase activity of FtsZ.[FtsZ] (Mus musculus) PubMed
8768.
The two consecutive glutamates in the beta4/alpha4 loop of T. maritima CheB that is absent in T. maritima CheY and in E. coli/S. typhimurium CheB may be one factor contributing to the low CheA affinity.[CheA, CheB] (Mus musculus) PubMed
8769.
The structure of PfCS along with cofactor FMN was predicted by homology modeling.[CS] (Mus musculus) PubMed
8770.
This study demonstrates that CAF1 of the CCR4-Not complex is a significant gene regulatory mechanism needed for Plasmodium development within the human host [CCR4-associated factor 1] (Mus musculus) PubMed
8771.
we identified the ligand binding surface and the critical residues responsible for ligand binding of HtrA PDZ domain by chemical shift perturbation and site-directed mutagenesis. [HtrA] (Mus musculus) PubMed
8772.
These data reveal that the Staphylococcus epidermidis SarX protein regulates the transcriptional activity of the agr and ica loci and controls the biofilm phenotype, primarily by regulating icaADBC transcription and PIA production.[SarX] (Mus musculus) PubMed
8773.
A gene encoding aminolevulinate synthase (ALA-S) in yeast (Saccharomyces cerevisiae YHem1) was introduced into the genome of tobacco (Nicoliana tabacum) under the control of Arabidopsis thaliana HemA1 gene promoter (AtHemA1 P).[YHem1] (Mus musculus) PubMed
8774.
These findings suggested a complicated transcriptional regulation of OsUgp2.[OsUgp2] (Mus musculus) PubMed
8775.
Data suggest that RctB has at least two DNA binding domains-one for binding to oriCII and initiating replication and the other for binding to rctA and thereby inhibiting RctB's ability to initiate replication: [rctA & rctB] (Mus musculus) PubMed
8776.
Pep plays a critical role in the pathogenesis. [Pep] (Mus musculus) PubMed
8777.
LAPTc is a 330-kDa homohexameric metalloaminopeptidase expressed by all T. cruzi forms and mediates the major parasite leucyl aminopeptidolytic activity. [LAPTc] (Mus musculus) PubMed
8778.
Overall, these results indicate that the muramidase activity of EtgA is not critical but makes a significant contribution to the efficiency of the type III secretion process.[EtgA] (Mus musculus) PubMed
8779.
Characterization of the structure and function of Escherichia coli DegQ as a representative of the DegQ-like proteases of bacterial HtrA family proteins. [DegQ] (Mus musculus) PubMed
8780.
structural models for PfMDR1 in different predicted conformations [PfMDR1] (Mus musculus) PubMed
8781.
modification of respiratory chain proteins and stress response proteins suggests the occurrence of a mild oxidative stress in anxC4 disruptant strain[annexin C4] (Mus musculus) PubMed
8782.
The authors have identified the acetyltransferase p300 as an additional target of Escherichia coli type III secreted protease NleC.[NleC] (Mus musculus) PubMed
8783.
All Asp-hemolysin mutant strains showed no attenuation in virulence in a mouse infection model for invasive pulmonary aspergillosis.[Asp-hemolysin] (Mus musculus) PubMed
8784.
IdiC is loosely attached to the thylakoid and to the cytoplasmic membranes and that its expression is enhanced during conditions of iron starvation and during the late growth phase.[IdiC] (Mus musculus) PubMed
8785.
Antigenic sites A and D in the S protein completely inhibit viral infection. [Spike protein, S protein] (Mus musculus) PubMed
8786.
Rev protein of Human Immunodeficiency Virus type 1 (HIV-1) inhibits nuclear import and mediates nuclear export of the HIV-1 integrase (IN) protein [integrase] (Mus musculus) PubMed
8787.
The crystal structure of endonuclease I has been solved both as free protein and in complex with a DNA junction, showing that the protein, as well as the junction, becomes distorted on binding. [T7 endonuclease I] (Mus musculus) PubMed
8788.
The interactions of C and histones add an interesting new role for the presence of C in the nucleus during Dengue virus infection.[Capsid protein] (Mus musculus) PubMed
8789.
P. falciparumRh5 interacting protein forms a complex with PfRh5 in merozoites. PfRipr protein localises to the apical end of the merozoites in micronemes whilst PfRh5 is contained within rhoptries and both are released during invasion[PfRipr] (Mus musculus) PubMed
8790.
By means of the energy decomposition method, the study identifies the residues that have the biggest influence on catalysis. [trans-sialidase] (Mus musculus) PubMed
8791.
Apical complex lysine (K) methyltransferase depletion greatly inhibits activation of motility, compromises Toxoplasma gondii invasion and egress, and thus severely impairs the lytic cycle[AKMT] (Mus musculus) PubMed
8792.
We expressed and purified a 13.4 kDa fragment of Engrailed 2, which comprises a 54-residue N-terminal extension in addition to the homeodomain region. Almost all backbone and side-chain resonances have been assigned. (Mus musculus) PubMed
8793.
Here we present the near complete assignment of Schistosoma mansoni IPSE/alpha-1 variant, IPSEDeltaNLS, which comprises the core domain of the protein. (Mus musculus) PubMed
8794.
The study reports the generation and biophysical characterization of deflavinated AidB and of an AidB mutant that has greatly reduced affinity for flavin adenine dinucleotide. [AidB] (Mus musculus) PubMed
8795.
The W56H variant showed an increased stability of the complex against autoxidation and a slower rate of O(2) activation. [nitric oxide synthase] (Mus musculus) PubMed
8796.
This study uses a combination of limited proteolysis, mass spectrometry, and N-terminal sequencing to precisely define the interaction region of Smc5 with Mms21. [Smc5, Mms21] (Mus musculus) PubMed
8797.
This study reports the structure of the 2-aminopurine-dCTP base pair formed within the polymerase active site of the RB69 Y567A-DNA polymerase. [DNA polymerase] (Mus musculus) PubMed
8798.
MltE and MltC regulated cell wall turnover and biofilm formation. [MltE] (Mus musculus) PubMed
8799.
CipB does not seem to participate in membrane depolarization to assist passage of DNA. [CipB] (Mus musculus) PubMed
8800.
MtrC protein trafficking to the outer membrane and its subsequent degradation are tightly regulated, which is consistent with cellular processing pathways that target MtrC to extracellular structures. (MtrC metal reductase) (Mus musculus) PubMed
OsGDI3 functions as a negative regulator of OsMAPK2 through modulating its kinase activity.[OsGDI3][OsMAPK2] (Mus musculus) PubMed
8803.
KRT31, KRT33A, KRT33B, KRT34, KRT36, KRT38-39, KRT81, KRT83 and KRT86-87 are expressed only in the fibre cortex. (Keratin 87) (Mus musculus) PubMed
8804.
Genetic interaction between Caenorhabditis elegans teneurin ten-1 and prolyl 4-hydroxylase phy-1 and their function in collagen IV-mediated basement membrane integrity during late elongation of the embryo. [phy-1] (Mus musculus) PubMed
8805.
These findings suggest that naturally acquired immunity against Pfs48/45 and Pfs230 is a function of recent exposure rather than of cumulative exposure to gametocytes.[Pfs48-45; Pfs230] (Mus musculus) PubMed
8806.
Both amino- (1-226) and carboxyl-terminal (196-403) parts of the LeIF protein were shown to induce significant levels of the three cytokines analysed.[LeIF] (Mus musculus) PubMed
8807.
Glycine max and Medicago extracellular fluids were each shown to possess an endoproteolytic activity that recognizes and cleaves at border sequences in a synthetic 31 amino acid CLE36.[CLE36] (Mus musculus) PubMed
8808.
A transcriptional and translational analysis of S. meliloti hfq expression by means of lacZ reporter fusions strongly suggests that the S. meliloti Hfq protein autocontrols its expression at the translational level (hfq). (Mus musculus) PubMed
8809.
POSTN is involved in conceptus elongation during early pregnancy.[Periostin; Ovis aries] (Mus musculus) PubMed
8810.
This study identify DCAR-1 as the first seven-transmembrane receptor required for avoidance of a water-soluble repellent, DHCA, in C. elegans. (Mus musculus) PubMed
8811.
(cagA) An inhibitory effect of H. pylori results from activation of the transcription factor heat shock factor(HSF)-1 by H. pylori virulence factor CagA and by host signaling molecules ERK1/2 and JNK kinases [CagA] (Mus musculus) PubMed
8812.
S. mutans lipoprotein PpiA contributes to suppression of MARCO-mediated phagocytosis of this bacterium by macrophages. [PpiA] (Mus musculus) PubMed
8813.
Epstein - Barr virus Latent Membrane Protein 1 suppresses reporter activity through modulation of promyelocytic leukemia protein-nuclear bodies. (Mus musculus) PubMed
8814.
The structural and mutagenesis analyses reported here establish ChuZ and ChuZ homologs as a new bacterial heme oxygenase family apart from the canonical and IsdG/I families.[ChuZ] (Mus musculus) PubMed
8815.
Localization of the beta giardin protein between assemblages A and B are different but localization of alpha-1 giardin in strains from assemblages A and B are the same. (Mus musculus) PubMed
8816.
Increased muscle activity after low-dose injections of botulinum toxin in mice does not influence the efficacy of the toxin in normal mouse muscles. (Mus musculus) PubMed
8817.
E. coli TopA may be modulated by iron and zinc binding in vivo [TopA] (Mus musculus) PubMed
8818.
OsGMST1 may play a direct or an indirect role in tolerance to salt stress in rice. (Mus musculus) PubMed
Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH [IsdH] (Mus musculus) PubMed
8821.
analysis of GlgE from Streptomyces and Mycobacterium tuberculosis [GlgE] (Mus musculus) PubMed
8822.
Dd-PIAS controls the developmental speed and duration of slug migration. Dd-PIAS does not affect Dd-STATa nuclear localization. [STATa; PIAS] (Mus musculus) PubMed
8823.
HSFd protein binds to heat shock elements and may activate mRNA expression of Hsp70a and Samui genes upon exposure of diapause eggs to 5 degrees C. [HSP70a] (Mus musculus) PubMed
8824.
The direct binding of the PmrA regulator to a specific promoter site induces the expression of the wzz(fepE) gene (PmrA and wzzfepE). (Mus musculus) PubMed
8825.
The results suggested that Paracoccidioides brasiliensis gp43 binds to human TLR2, TLR4, and mannose receptors, with TLR2 and mannose receptors having the strongest effect.[gp43] (Mus musculus) PubMed
8826.
Rrd1 is a novel transcription elongation factor that fine-tunes the transcriptional stress response of RNAPII.[Rrd1] (Mus musculus) PubMed
8827.
Viral capture of an ankyrin-like domain in Epstein-Barr virus BZLF1 ZEBRA protein provides a mechanism for binding to proteins in the NF-kappaB and p53 transcription factor families. (Mus musculus) PubMed
8828.
PcaQ regulates the expression of the S. meliloti smb20568-smb20787-smb20786-smb20785-smb20784 gene cluster, which is predicted to encode an ABC transport system (PcaQ). (Mus musculus) PubMed
8829.
mice immunized intranasally with the FlaB-PspA fusion protein were the most protected from a lethal challenge with live S. pneumoniae [FlaB] (Mus musculus) PubMed
8830.
Structural and functional analysis of the tandem beta-zipper interaction of a Streptococcal protein with human fibronectin [SfbI-5] (Mus musculus) PubMed
8831.
Our data showed that a prime-boost immunization using heterologous MPR 649-684-displaying immunogens, i.e., F1-V MPR 649-684 and CTB MPR 649-684, may provide a solution to overcome the poor humoral immunogenicity of MPR 649-684. [gp41] (Mus musculus) PubMed
8832.
H-NS silencing of hilA is antagonized by integration host factor (H-NS, hilA and integration host factor). (Mus musculus) PubMed
8833.
The functional role of ghrelin and peripheral GHS-R1a for the regulation of gastrointestinal motility is weak in the guinea-pig. (Mus musculus) PubMed
8834.
Nasal administration of Flt3 ligand cDNA with Phosphorylcholine may contribute to the development of nasal vaccination for prevention of S. pneumoniae infection. [Flt3] (Mus musculus) PubMed
8835.
results show segment 7 and 8 mRNAs of A/Brevig Mission/1918/1 (H1N1) were inefficiently spliced; this resulted in production of higher levels of NS1 protein, which could potentially contribute to its pathogenic properties [NS1] (Mus musculus) PubMed
8836.
Data present the crystal structures of Schizosaccharomyces pombe aprataxin Hnt3 and dsDNA-AMP reveal how Hnt3 recognizes and processes 5'-adenylated DNA in a structure-specific manner. (Mus musculus) PubMed
8837.
TbSA C2 utilized alpha2-3 sialyllactose as a donor, and produced an alpha2-3-sialylated product, suggesting that it is an alpha2-3 trans-sialidase; TbSA C2 plays a role in the sialic acid modification of the trypanosome cell surface. [TbSAC2] (Mus musculus) PubMed
8838.
The substrate specificity of the Aro8 encoded aminotransferase was investigated; The enzyme should be classified as an alpha-aminoadipate aminotransferase. [alpha-aminoadipate aminotransferase] (Mus musculus) PubMed
8839.
This study reports the cloning and characterization of a putative type III polyketide synthase from Aspergillusniger, AnPKS. [AnPKS] (Mus musculus) PubMed
8840.
the gating mechanism of a type II ABC importer, the BtuCD-F vitamin B(12) importer from Escherichia coli [BtuCD-F] (Mus musculus) PubMed
8841.
The chaperonin TRiC was shown to assist an ATP-dependent refolding of recombinant forms of sperm-specific glyceraldehyde-3-phosphate dehydrogenase. [chaperonin TRiC] (Mus musculus) PubMed
8842.
The autophagic process was blocked in the ATG5 deletion mutant. [ATG5] (Mus musculus) PubMed
8843.
Identification of the keratin-associated protein KAP1-2 gene (KRTAP1-2). PCR-SSCP analysis of KRTAP1-2 revealed nine unique banding patterns representing nine different DNA sequences. (KRTAP1-2). (Mus musculus) PubMed
8844.
the identification and dynamics characterization of a tvMyb2 fragment comprising amino acid residues 40-156 (tvMyb240-156) as the minimum structural unit that retains near full binding affinity with the ap65-1 gene promoter DNA (Myb2). (Mus musculus) PubMed
8845.
two major R genes, designated Pi47 and Pi48, were located between RM206 and RM224 on chromosome 11, and between RM5364 and RM7102 on chromosome 12, respectively [Pi47;Pi48] (Mus musculus) PubMed
8846.
The authors show that Qs, an RNA from the 5' end of the prgQ operon, represses expression of PrgX by targeting prgX mRNA for cleavage by RNase III.[RNase III] (Mus musculus) PubMed
8847.
Fe-S clusters synthesis is regulated by the leucine biosynthetic pathway involving Leu1p and Aco1p [Atm1p][Aco1p][Leu1p] (Mus musculus) PubMed
8848.
Cooperativity of cAMP binding is generally correlated to the global dynamics of the protein and DNA binding affinity. [cAMP binding receptor protein] (Mus musculus) PubMed
8849.
study determined whether ongoing expression of HPV16 or HPV18 oncogenes is required for the proliferation of primary human cervical carcinoma cells; data suggest that E6 and E7 dependence is an inherent property of human cervical cancer cells [E6,E7] (Mus musculus) PubMed
8850.
Our results support a role for RIC8 in regulating GNA-1 and GNA-3 in Neurospora. (Mus musculus) PubMed
8851.
The L98H induced relocation of tyrosine 121 and tyrosine 107 seems to be related to the multi-azole-resistance phenotype, without affecting the biological activity of the CYP51A protein.[CYP51A] (Mus musculus) PubMed
8852.
allosterism between the nucleotide and DNA binding sites in MutS can occur via ligand-induced changes in motion, i.e., dynamical allosterism [MutS] (Mus musculus) PubMed
8853.
Sgs4 and Sgs5 are produced exclusively in female salivary glands [Sgs4][Sgs5] (Mus musculus) PubMed
8854.
relative ligand binding free energy by mutating tryptophans in the Trichoderma reesei family 6 cellulase (Cel6A) to alanine [Cel6A] (Mus musculus) PubMed
8855.
[differentiation inducing factor 1; DIF-1]Inhibits Wnt/beta-catenin signaling pathway by suppressing transcription factor 7-like 2 expression via reduced early growth response (Egr)-1-dependent transcriptional activity in human colon cancer cells (Mus musculus) PubMed
8856.
Both Isa1 and Isa2 are indispensable for growth, as they are required for the assembly of Fe-S clusters in mitochondrial aconitase, fumarase and succinate dehydrogenase.[Isa1 and Isa2] (Mus musculus) PubMed
8857.
The present study establishes TNC as a functional plasma membrane nickel transporter necessary for physiological acquisition of nickel in the multicellular fungi Neurospora crassa.[TNC] (Mus musculus) PubMed
8858.
Expression of the metalloreductase FreB was found to be transcriptionally repressed by iron via SreA, a repressor of iron acquisition during iron sufficiency, indicating a role in iron metabolism.[FreB] (Mus musculus) PubMed
8859.
PhoB binding to distinct Pho boxes enables the precise control of phoBR expression. [PhoB, PhoR] (Mus musculus) PubMed
8860.
Srr1, Srr2 and PilA contribute to adherence to vaginal epithelial cells. [Srr1, Srr2, PilA] (Mus musculus) PubMed
8861.
Bap1 was concentrated at the biofilm-surface interface and stabilized the association of the multilayer biofilm with the surface. [BAP1] (Mus musculus) PubMed
8862.
In this study, we have identified a new posterior body contraction calcium-binding protein, PBO-1/CHP, that regulates at least two intestinal sodium-proton exchangers in C. elegans [pbo-1] (Mus musculus) PubMed
8863.
NanR, CRP, and N-acetylmannosamine 6-phosphate cooperate for precise adjustment of the expression level of the V. vulnificus nan cluster (Mus musculus) PubMed
8864.
the 1-600-amino acid domain of DPB11 is both required and sufficient for full replication function of Dpb11 but that this domain is defective for activation of the principal checkpoint kinase Mec1 in vitro and in vivo.[Dpb11] (Mus musculus) PubMed
8865.
The authors concluded that the central regulatory unit composed of AdpA and BldA plays important roles in the initiation of morphological differentiation and secondary metabolism triggered by A-factor.[BldA] (Mus musculus) PubMed
8866.
Transcription factor NusA modulates the transcriptional pausing of RNA polymerase in Escherichia coli. (Mus musculus) PubMed
8867.
These data suggest that rak1 is a regulator of rop1 expression with additional roles after cell fusion.[Rak1] (Mus musculus) PubMed
8868.
Secretion of SmHMGB1 is regulated by phosphorylation.[HMGB1] (Mus musculus) PubMed
8869.
The study examines SSB binding to shorter oligodeoxynucleotides ((dX)35) to probe whether this effect requires binding of one or two (dX)35 molecules per SSB tetramer. [SSB] (Mus musculus) PubMed
8870.
These results document a distinct transcriptional profile invoked by the HIV-1/V3 epitope.[gp120] (Mus musculus) PubMed
8871.
This study describes two novel regulators, GalX and GalR, that control d-galactose utilization in Aspergillus nidulans.[GalX and GalR] (Mus musculus) PubMed
8872.
The data presented here show that glycosylphosphatidylinositol-linked alkaline phosphatase (GPI-ALP) from Aedes aegypti has high-affinity binding to Bacillus thuringiensis Cry4Ba toxin even in the absence of protein glycosylation.[GPI-ALP] (Mus musculus) PubMed
8873.
The beta-agarase AgaA(CN41) belongs to the GH50 (glycoside hydrolase 50) family but yields neoagarotetraose as the end product.[AgaA] (Mus musculus) PubMed
8874.
A GFP::MtRopGEF2 fusion protein localizes in the apex of emerging and actively growing root hairs. The amino terminus of MtRopGEF2 regulates its ability to interact with MtRops in yeast, and regulates its biological activity in vivo.[RopGEF] (Mus musculus) PubMed
8875.
Medicago truncatula Vapyrin (VPY) gene is required for rhizobial colonization and nodulation. (Mus musculus) PubMed
8876.
findings show that pcsB is not essential for cell survival but is essential for proper cell division;data suggest that LysM domain proteins partially compensate for the lack of PcsB function and allow the survival and slow growth of the pneumococcus (Mus musculus) PubMed
8877.
results indicate that MNX1 and MNX2 code for flavoprotein monooxygenases catalysing the first steps in the 3-oxoadipate and gentisate pathways, respectively ( 4-hydroxybenzoate 1-hydroxylase and 3-hydroxybenzoate 6-hydroxylase)[MNX1, MNX2] (Mus musculus) PubMed
8878.
Streptococcus gordonii FSS2, an infective endocarditis isolate, expresses a dipeptidyl-carboxypeptidase with activity homologous to angiotensin-converting enzyme [challisin] (Mus musculus) PubMed
8879.
conformational changes in the protein's ATPase site in solution (Mus musculus) PubMed
8880.
Two internal NDH2 isoforms are both required for optimal tachyzoite growth. [NDH2] (Mus musculus) PubMed
8881.
PKA-dependent regulation of Cdc25 RasGEF localization [Tpk1][Cdc25] (Mus musculus) PubMed
8882.
subunit coordination may be general to many ring-shaped helicases and reveals a potential mechanism for regulation of DNA unwinding during replication [gene product 4] (Mus musculus) PubMed
8883.
The authors suggest that the continued engagement of the receptor binding protein is essential to F protein function until the onset of membrane merger.[HN] (Mus musculus) PubMed
8884.
The lymphocytic choriomeningitis virus nucleoprotein domain that interacted with Z overlapped with a previously documented C-terminal domain that counteracts the host type I interferon (IFN) response.[Z] (Mus musculus) PubMed
8885.
Overall, the results presented here point toward an important role for PCBP1 and PCBP2 in regulating porcine reproductive and respiratory syndrome virus RNA synthesis via binding to viral nonstructural protein 1beta.[nonstructural protein 1beta] (Mus musculus) PubMed
8886.
ScbR2 negatively controls the biosynthesis of gamma-butyrolactone by directly repressing the transcription of scbA. [ScbR2] (Mus musculus) PubMed
8887.
GEST mediates malaria transmission to both mosquito and vertebrate host. {GEST] (Mus musculus) PubMed
8888.
Wzd and Wze are spatial regulators of capsular polysaccharide synthesis.[Wzd, Wze] (Mus musculus) PubMed
8889.
SbP5CS1 and SbP5CS2 are stress inducible genes but might play non-redundant roles in plant development. [SbP5CS1; SbP5CS2] (Mus musculus) PubMed
8890.
RMR1 functions as a sorting receptor in transporting vicilin-like storage proteins. [RMR1] (Mus musculus) PubMed
8891.
function of two hydrophobic domains in the C-terminal region of the Tob37 protein and Tob38 protein [Tob37][Tob38] (Mus musculus) PubMed
8892.
comprehensive information on the CRE-1 regulon in N. crassa [CRE-1] (Mus musculus) PubMed
8893.
TRIM79 restricts tick-borne encephalitis virus replication by degradation the NS5 protein, an RNA-dependent RNA polymerase essential for virus replication. [NS5] (Mus musculus) PubMed
8894.
The authors provide evidence that the Kluyveromyces lactis KlPDR1 gene is under positive autoregulation by KlPdr1p, which plays a role in the activation of the main multidrug resistance transporter gene KlPDR5.[KlPDR1] (Mus musculus) PubMed
8895.
the residual resection observed in Exo1-mutant cells is dependent on Mre11, and both exonuclease activities are required for efficient DNA double-strand break repair [Exo1 & Mre11] (Mus musculus) PubMed
8896.
identification of an iron-dependent sulphide transfer reaction from a conserved cysteine residue of the protein to a reaction intermediate and the demonstration that THI4p is a suicide enzyme undergoing only a single turnover [THI4] (Mus musculus) PubMed
8897.
IcmF mutant has decreased adherence to and invasion of epithelial cells and decreased intra-macrophage survival. [IcmF] (Mus musculus) PubMed
8898.
HNS control the integrase IntI1 and integron promoters expression. [IntI1] (Mus musculus) PubMed
8899.
PKB/Akt expression decreased in adrenocortical cells induced by cadmium chloride. [PKB] (Mus musculus) PubMed
8900.
OsKNOLLE plays a crucial role in responses to abiotic stresses. [KNOLLE] (Mus musculus) PubMed
8901.
The first negative regulatory histone methylation is observed in budding yeast and indicates that histone H4 lysine 20 is evolutionarily conserved from simple to complex eukaryotes. (Mus musculus) PubMed
8902.
an additional subunit of the Gid complex containing a degenerated RING finger, Gid9/Fyv10 [Gid9] (Mus musculus) PubMed
8903.
Rvb2 physically associates with telomerase/Est2 in vivo [Rvb2][Est2] (Mus musculus) PubMed
8904.
the inhibitory effect of alpha(1)-antitrypsin on the catalytic activity of trypsin [alpha(1)-antitrypsin][trypsin] (Mus musculus) PubMed
8905.
Chlamydia trachomatis CPAF secretion in the cytosol of host epithelial cells is decreased. [CPAF] (Mus musculus) PubMed
8906.
These data suggest that Pga1 plays an important role in cell wall rigidity and stability.[Pga1] (Mus musculus) PubMed
8907.
H. pylori DsbG functions as a reductase against HP0518, a putative L,D-transpeptidase with a catalytic cysteine residue [DsbG] (Mus musculus) PubMed
8908.
the role of GTP hydrolysis in FtsZ function and cell division [FtsZ] (Mus musculus) PubMed
8909.
Saccharomyces cerevisiae Rad51 paralogues, the Rad55-Rad57 heterodimer, counteract the antirecombination activity of the Srs2 helicase [rad55, rad57, srs2, & rad51] (Mus musculus) PubMed
8910.
HSV-1 gene expression from reactivated ganglia is disordered and concurrent with suppression of latency-associated transcript and miRNAs [LAT] (Mus musculus) PubMed
8911.
covariance of the 243(rd) nucleotide of the 5'UTR with NS2 and NS3 [NS2][NS3] (Mus musculus) PubMed
8912.
PmFKBP46 might be involved in genome packaging by viral VP15 during virion assembly [VP15] (Mus musculus) PubMed
8913.
disease in BALB/c mice and Wistar rats infected by the rodent malaria parasite Plasmodium berghei with a gene knock out for merozoite surface protein (MSP) 7 (Mus musculus) PubMed
8914.
Mosquito Aedes aegypti (L.) leucokinin receptor is critical for in vivo fluid excretion post blood feeding. [leucokinin receptor] (Mus musculus) PubMed
8915.
phenotype of a conditional mutant impaired in host cell invasion and egress was pinpointed to a defect in secretion of the micronemes; sequencing identified the etiological point mutation in TgDOC2.1[TgDOC2.1] (Mus musculus) PubMed
8916.
Pdr5p (pleiotropic drug resistance gene)is a main actor in the efficacy of lovastatin in S. cerevisiae. (Pdr5p) (Mus musculus) PubMed
PerC and GrlA independently regulate Ler expression. [PerC, GrlA, Ler] (Mus musculus) PubMed
8919.
our data reveal a potential new role for Swap70 in regulating transition of dividing neural precursors to specified oligodendrocyte progenitor cells (Swap70). (Mus musculus) PubMed
8920.
the structural basis of cotransporter water permeability (Mus musculus) PubMed
8921.
These findings provide the first evidence that yeast septin proteins are acetylated and that NuA4 impacts septin dynamics.[NuA4] (Mus musculus) PubMed
8922.
Report expression of keratin 19 and NKCC1 in developing mammary glands. (Mus musculus) PubMed
8923.
OIP30 belongs to the RuvBL2 DNA helicase 2 subfamily, and is an OsCPK25/26-interacting protein in pollen. (Mus musculus) PubMed
8924.
The association of Cna1 with Sec28 and Sec13 was confirmed by co-immunoprecipitation.[Calcineurin, Sec28, Sec13] (Mus musculus) PubMed
8925.
An insertional mutant Z39P105 with a defect in sexual development was characterised and a gene encoding a putative transcription factor designated as MYT1, was identified.[MYT1] (Mus musculus) PubMed
8926.
The peroxide regulator can positively regulate the expression of the secreted protein MF3 that contributes to the virulence in S. pyogenes[MF3],[PerR] (Mus musculus) PubMed
8927.
the mutations of walK and clpP identified in LR5P1-V3 constitute a new combination of genetic events causing vancomycin resistance in Staphylococcus aureus. (Mus musculus) PubMed
8928.
Deletion of the Aspergillus nidulans flavohemoglobin gene fhbA induced sexual development and decreased sterigmatocystin production. [fhbA] (Mus musculus) PubMed
8929.
SidL is a constitutively active N5-hydroxyornithine-acetylase required for ferricrocin biosynthesis, in particular under iron-replete conditions. [SidL] (Mus musculus) PubMed
8930.
The result provide key insights into the regulation of homolog pairing and reveal that targeting of plk-2 to the NE by meiotic chromosomes establishes the conserved linkages to cytoskeletal forces needed for homology assessment.(Polo Kinase-2) (Mus musculus) PubMed
8931.
This work reveals unexpected functions for the conserved PLK-2, and advances understanding of how meiotic processes are properly coordinated to ensure transmission of genetic information from parents to progeny.(Polo Kinase-2) (Mus musculus) PubMed
8932.
The role of Low-density lipoprotein receptor-related protein 2 (LRP2) in lipoprotein metabolism and egg quality traitrs is reported.[LRP2] (Mus musculus) PubMed
8933.
The results of the binding of RecA from E. coli and T. thermophilus show adaptation to pressure and temperature at the single protein level.[RecA] (Mus musculus) PubMed
8934.
study identifed protease chlamydial protease-like activity factor (CPAF) as the factor mediating cleavage of golgin-84 and as the target of WEHD-fmk-inhibition; results define CPAF as the first protein that is essential for replication of Chlamydia [CPAF] (Mus musculus) PubMed
8935.
study assessed the fitness cost associated with the expression in S. aureus cells of the cfr gene alone or in combination with ermB[cfr] (Mus musculus) PubMed
8936.
proteins that directly or indirectly affect Sup35p aggregation and [PSI(+)] formation (Mus musculus) PubMed
8937.
The phosphorylation of the Rab Sec4p prevents interactions with its effector, the exocyst component Sec15p, and that the inhibition may be relieved by a PP2A phosphatase complex containing the regulatory subunit Cdc55p.[Sec4p] (Mus musculus) PubMed
8938.
The second endocytic pathway, that depends on the GTPase Rho1 and the downstream formin Bni1, and the Bni1 cofactors Bud6 and Spa2. (Mus musculus) PubMed
8939.
The nonphosphorylatable Nsk1 mutant binds prematurely to kinetochores and spindle, cementing improper k-MT attachments and leading to high rates of lagging chromosomes that missegregate.(Nsk1 & cdk1) (Mus musculus) PubMed
8940.
The result establish Tim50 as the primary presequence receptor at the inner membrane and show that targeting signals and Tim50 regulate the Tim23 channel in an antagonistic manner.( Tim50 ) (Mus musculus) PubMed
8941.
The results suggest that the number of CSE4 molecules exceeds the number of kinetochore-microtubule attachment sites on each chromosome and that CSE4 is not the sole determinant of kinetochore assembly sites in Saccharomyces cerevisiae.(CSE4 protein) (Mus musculus) PubMed
8942.
The Cse4 may be associated with the CEN nucleosome, and Cse4 could be located within flanking nucleosomes at random sites that differ between chromosomes. (Mus musculus) PubMed
8943.
the Myo4p, one of two class V myosins in budding yeast, continuously transports messenger RNA (mRNA) cargo in the cell but is nonprocessive when characterized in vitro.(Myo4p) (Mus musculus) PubMed
8944.
Signal transduction kinases Mec1 (ATR) and Tel1 (ATM) mutants exhibit only one double-strand breaks occurs per four chromatids.[Mec1, Tel1] (Mus musculus) PubMed
8945.
C6 inhibits the activation of IRF3 and IRF7 downstream of the kinases TBK1 and IKKepsilon, while C6 does not inhibit signalling pathways using IKKalpha for IRF7 activation. [C6] (Mus musculus) PubMed
8946.
The HIV-1 protease (pro) gene was sequenced to view the distribution of sequence variation of a complex viral population within a host.[Hiv-1 protease] (Mus musculus) PubMed
8947.
crystals of protein 2AB belonged to space group P4(1) or P4(3), with unit-cell parameters a = b = 90.42, c = 73.43 A, and contained two molecules in the asymmetric unit[protein 2A, protein 2B ] (Mus musculus) PubMed
8948.
HtpG is a newly identified positive modulator of the clustered regularly interspaced short palindromic repeats system that is essential for maintaining functional levels of Cas3. (Mus musculus) PubMed
8949.
The results of the binding of RecA from E. coli and T. thermophilus show adaptation to pressure and temperature at the single protein level.[RecA] (Mus musculus) PubMed
8950.
The 3.0 A-resolution X-ray crystal structure of gp33 complexed with its RNA polymerase binding determinant, the beta-flap domain, was determined.[rpob] (Mus musculus) PubMed
8951.
kinetics and thermodynamic characterization of the SePat enzyme [Pat,N(epsilon)-lysine acetyltransferase] (Mus musculus) PubMed
8952.
Disruption of YlTPS1 drastically slowed growth at 35 degrees C. [YlTPS1] (Mus musculus) PubMed
8953.
Recombinant betaine aldehyde dehydrogenase 2 was successfully expressed in E. coli as an N-terminal hexahistidine fusion protein and was purified using Ni Sepharose affinity chromatography[betaine aldehyde dehydrogenase 2] (Mus musculus) PubMed
8954.
ChuZ-haemin complex crystals belonged to space group C222(1), with unit-cell parameters a = 106.474, b = 106.698, c = 52.464 A, alpha = beta = gamma = 90 degrees [ChuZ] (Mus musculus) PubMed
8955.
Diamond-shaped crystals of DeltaN(59)sortase A diffracted to 4.0 A resolution and belonged to a tetragonal system with unit-cell parameters a = b = 122.8, c = 86.5 A, alpha = beta = gamma = 90 degrees [sortase A] (Mus musculus) PubMed
8956.
Form I of HA3 belonged to space group R32, with unit-cell parameters a = b = 357.4, c = 249.5 A, alpha = beta = 90, gamma = 120 degrees [HA3 ] (Mus musculus) PubMed
8957.
ROP16 deletion converts Type I tachyzoites from low to high inducers of IL-12p40, and simultaneously abrogates the suppressive effect of Toxoplasma on TLR signaling. [ROP16] (Mus musculus) PubMed
8958.
The crystal structure of the DF complex of the prokaryotic V-ATPase of Enterococcus hirae at 2.0-A resolution, was demonstrated.[V-ATPase D, V-ATPase F] (Mus musculus) PubMed
8959.
The characterization of another recessive resistance gene, xa25, for Xoo resistance, is reported.[Xa25] (Mus musculus) PubMed
8960.
RSOsPR10 protein accumulated mainly in the root cortex cells after abiotic stresses and application of plant hormones. (Mus musculus) PubMed
8961.
Unusual N-glycan structures required for trafficking Toxoplasma gondii GAP50 to the inner membrane complex regulate host cell entry through parasite motility. (Mus musculus) PubMed
8962.
TMC647078 is a potent and speci fi c novel nucleoside inhibitor of the HCV NS5B RdRp with broad genotypic coverage and a high barrier to resistance. [NS5b] (Mus musculus) PubMed
8963.
The N terminus of NS5A has been crystallized as a dimer, complementing the symmetry of BMS-346 and allowing a potential mode of inhibition of NS5A to be discussed. [NS5a] (Mus musculus) PubMed
8964.
This is the first report of tet(B) in streptococci, a Gram positive bacterium. tet(B) was detected in plasmid extracts from 17/111 (15%) Streptococcus suis isolates from diseased pigs. (Mus musculus) PubMed
8965.
The Cdc50p may play an important role for phospholipid translocation by Drs2p.(Cdc50p protein) (Mus musculus) PubMed
8966.
This study shows that sigma A factor does not bind to the vraSR operon control region in the absence of VraR, suggesting that VraR may interact directly with this factor.[VraR] (Mus musculus) PubMed
8967.
Study identifies Stk as an important regulator of biofilm formation and virulence of S. epidermidis, with additional involvement in purine metabolism and the bacterial stress response. [Stk] (Mus musculus) PubMed
8968.
SrtA is required for pili cell wall covalent attachment, acting exclusively on the minor accessory pilin, representing the terminal subunit located at the base of the pilus.[Sortase A] (Mus musculus) PubMed
8969.
IreK and IreP act antagonistically via protein phosphorylation and dephosphorylation to regulate cellular adaptation to cephalosporin-induced stress. [IreK, IreP] (Mus musculus) PubMed
8970.
A metabolic control analysis-based strategy demonstrated that most of the lysine biosynthesis control resided on the non-cooperative and weakly feedback-inhibited Lys20 isoform.[Lys20] (Mus musculus) PubMed
8971.
The data provide new insight into simultaneously occurring counter-acting effects of HEV ORF2 that may be part of a strategy to prevent host suicide before completion of the viral replication cycle. [ORF2] (Mus musculus) PubMed
8972.
These results indicate that the F-actin-targeting effector VopV is involved in enterotoxic activity of type III secretion system 2-possessing bacterial pathogens.[VopV] (Mus musculus) PubMed
EglA cDNA contains 717 bp and encoded a 238 aa endoglucanase with a predicted molecular mass of 26 kDa. [EglA] (Mus musculus) PubMed
8975.
A single dose of insulin-like peptide 3, sufficient to stimulate egg development, rescues hemocyte proliferation. [ILP3] (Mus musculus) PubMed
8976.
Silencing of Nox1 indicated a central role for this enzyme in both virulence and pathogenic development, while inactivation of the Nox2 gene resulted in limited sclerotial development, but the organism remained fully pathogenic.[Nox1 & Nox2] (Mus musculus) PubMed
8977.
During Caenorhabditis elegans meiosis, loading of cohesin requires SCC-2, whereas the cohesin-related complexes condensin and SMC-5/6 can be loaded by mechanisms independent of both SCC-2 and cohesin.[scc-2] (Mus musculus) PubMed
8978.
These results indicate that purified leukotoxin LukM/F' is not likely to contribute to the initiation of the inflammatory response and could even play an anti-inflammatory role in the mammary gland by inactivating macrophages.[LukM & LukF] (Mus musculus) PubMed
8979.
The Deltastp was attenuated in a CD1 murine model of infection and its LD50 values was seven-fold higher than the wild type.[stp] (Mus musculus) PubMed
8980.
[sortase A, SrtA] Both in vitro and in vivo evidence show that transpeptidase SrtA increases S. pyogenes' resistance against the bactericidal activity of human group IIA-secreted phospholipase A2 (PLA2-IIA). (Mus musculus) PubMed
8981.
It can be concluded that rpoZ is controlled negatively by PhoP, thus connecting phosphate depletion regulation with antibiotic production and morphological differentiation in Streptomyces.[rpoZ & PhoP] (Mus musculus) PubMed
8982.
Ndi1 expression did not trigger any inflammatory or immune response in rats.[Ndi1] (Mus musculus) PubMed
8983.
[gp150; glycoprotein 150] A mouse transgenic for a gp150-specific T-cell receptor displays epitope-specific activation of transgenic CD4 T cells during acute and latent gamma-herpesvirus infections. (Mus musculus) PubMed
8984.
TaFKBP13 interacts with TaRieske in the wheat thylakoid. [FKBP13] (Mus musculus) PubMed
8985.
Isolation and identification of an AP2/ERF factor that binds an allelic cis-element of rice gene LRK6 (Mus musculus) PubMed
8986.
The fates of absorbed light energy in PSII were quantitatively estimated by the typical energy allocation models using transgenic rice in which psbS genes were silenced by RNA interference.[PsbS1, PsbS2] (Mus musculus) PubMed
8987.
both motors participate in early endosomes motility, with dynein transporting the organelles through the unipolar MT array near the cell ends, and kinesin-3 taking over at the beginning of the medial antipolar microtubule array. [kinesin-3] [dynein] (Mus musculus) PubMed
8988.
uhd1 deletion strains produced ustilagic acid lacking the beta-hydroxyl group of the short-chain fatty acid.[uhd1] (Mus musculus) PubMed
8989.
These results suggest different binding specificities of Efg1 in yeast growth and in hyphal induction and suggest a brief time window following hyphal induction, in which Efg1 exerts its repressive effect on target promoters.[Efg1] (Mus musculus) PubMed
8990.
Surprisingly, conditional knockout indicates that TbRab7 may be non-essential in procyclic insect form trypanosomes.[Rab7] (Mus musculus) PubMed
8991.
IRE-BP 1 transcription level was 6.7 times higher in the cypermethrin-resistant strain than in the susceptible strain. [ IRE-BP 1] (Mus musculus) PubMed
8992.
msw, by controlling Kupffer's vesicle morphogenesis, controls lateralized behaviors related to diencephalic asymmetries.[msw] (Mus musculus) PubMed
8993.
C. elegans mutants of the genes for the OSA/BAF250 homolog, LET-526, and the Polybromo homolog, PBRM-1, in a screen for the abnormal asymmetric cell division phenotype, were isolated.[PBRM-1, LET-526] (Mus musculus) PubMed
8994.
Data show that the death pathway is independent of ERK but relies on activating Bad phosphorylation through the control of both kinases Cdk1 and JNK: [Bad] (Mus musculus) PubMed
8995.
Certain Spt16 activities collaborate with histone acetylation and the activities of a Bur-kinase/Spt4-Spt5/Paf1C pathway that facilitate transcription elongation.[FACT, Bur1, Bur2, HirC] (Mus musculus) PubMed
8996.
The study shows isolation of yeast minimal RNA polymerase II open complexes and regulation by TFIIF. [TFIIF] (Mus musculus) PubMed
8997.
Inoculation of the long-stalk-neuraminidase virus resulted in a higher cloacal excretion in ducks and lower-level oropharyngeal excretion in chickens. (Mus musculus) PubMed
8998.
A strong association was found between HIV-2 phenotypic tropism and gp105 V3-loop sequences, allowing for the prediction of R5- and/or X4-tropic viruses in HIV-2 infection. [HIV-2 gp105 envelope glycoprotein] (Mus musculus) PubMed
8999.
Rem folding and cleavage is required for retrotranslocation and escape from endoplasmic reticulum-associated degradation. (Mus musculus) PubMed
9000.
NS5 N-terminal capping enzymes binding the 5' end of the viral RNA was observed escence polarization-based RNA binding assay.[NS5] (Mus musculus) PubMed
9001.
NhaA's binding site is relatively promiscuous and that the selectivity is determined at a later stage of the transport cycle.[NhaA] (Mus musculus) PubMed
9002.
The energy dissipation model is applied to investigate E. coli aspartokinase III mutations to better understand the desensitization of product feedback inhibition via allostery.[Aspartokinase III] (Mus musculus) PubMed
9003.
Data indicate that the expression of RamA promoted the development of ciprofloxacin resistant mutants of S. enterica serovar Typhimurium: [RamA] (Mus musculus) PubMed
9004.
These results indicate that speB expression in M1 strains is induced by environmental pH changes but is not regulated by the LuxS signalling pathway. [SpeB, LuxS]] (Mus musculus) PubMed
9005.
The stretching of actin filaments, the preferential binding of myosin II filaments to stretched actin filaments, and myosin II-dependent contraction form a positive feedback loop that contributes to the stabilization of cell polarity.[Myosin II] (Mus musculus) PubMed
9006.
Degradation of intestinal cathelicidins is a novel function of Entamoeba histolytica cysteine proteinases in the evasion of the innate immune system in the bowel.[CP1] (Mus musculus) PubMed
9007.
heme, a molecule from the blood digestion, triggers epimastigote proliferation through a redox-sensitive signalling mechanism, through activation of camkII.[CaMKII] (Mus musculus) PubMed
9008.
These data suggest that PLD of Aspergillus fumigatus regulates its internalization into lung epithelial cells and may represent an important virulence factor for Aspergillus fumigatus infection.[PLD] (Mus musculus) PubMed
9009.
These in vivo data show that Gdh1p is the primary glutamate dehydrogenase enzyme and Gdh2p and Gdh3p play evident roles during aerobic glutamate metabolism.[Gdh1, Gdh2 and Gdh3] (Mus musculus) PubMed
9010.
The gene knockdown of CaM Kinase I delta using morpholino-based antisense oligonucleotides induced significant morphological abnormalities in zebrafish embryos. [CaM Kinase I delta] (Mus musculus) PubMed
9011.
The ability of tomosyn to regulate neurotransmitter release in vivo depends on the physical integrity of the protein, indicating that both N- and C-terminal domains are necessary but not sufficient for effective inhibition of release in vivo.[Tomosyn] (Mus musculus) PubMed
9012.
Thermal denaturation studies demonstrated that Ser88 and His91 both play crucial roles in the stability of the protein as their mutants showed a decrease in the melting temperature. [Arginase] (Mus musculus) PubMed
9013.
Data suggest that the transition between two dimer architectures represents the transition between the 'on' and 'off' states of YeaZ: [YeaZ] (Mus musculus) PubMed
9014.
Transcriptional analysis of devA and devE indicates that they are expressed at different stages of the lifecycle [devA][devE] (Mus musculus) PubMed
9015.
the effect of residue 227 in HA on cell tropism and transmission of pH1N1 2009 [HA] (Mus musculus) PubMed
ClpXP proteases function in the signaling pathway of the Escherichia coli extracellular stress response. [ClpXP] (Mus musculus) PubMed
9018.
The OsNAS genes, particularly OsNAS2(Os03g19420), show enormous potential for Fe and Zn biofortification of rice endosperm. [OsNAS2] (Mus musculus) PubMed
These results may suggest that Toxoplasma gondii PL1 moves to the parasitophorous vacuole to protect parasites from nitric oxide by an undetermined mechanism.[PL1] (Mus musculus) PubMed
9021.
Starch biosynthesis in rice endosperm requires the presence of either starch synthase I or IIIa.[SS3a] (Mus musculus) PubMed
9022.
Phenotypic and molecular analyses of transgenic lines provided direct evidence for ALK as a key gene for gelatinization temperature.[ALK] (Mus musculus) PubMed
Expression of VRN1 increased before flowering date, then decreased after flowering time. Expression of VRN2 was only detected in the leaves at the 3-leaf stage and in the embryo buds during seeds germination. [VRN1; VRN2] (Mus musculus) PubMed
9025.
Overexpression of OsAGAP, an ARF-GTPase-activating protein in rice, stimulates vesicle transport from the plasma membrane to the Golgi apparatus in protoplasts and transgenic plants and induces the accumulation of early endosomes and AUX1.[AUX1, OsAGAP] (Mus musculus) PubMed
9026.
ZRA1 is involved in zearalenone production and shares a common regulatory mode with ZEA cluster genes [ZRA1] (Mus musculus) PubMed
9027.
DupA seems to protect against gastic ulcer and gastric cancer development, whereas a positive association was observed between the occurrence of duodenal ulcer and the presence of DupA. [DupA] (Mus musculus) PubMed
9028.
These results suggest that Gcn2, by phosphorylating eIF2alpha, may activate translation of an unknown regulator of amino acid transporters different from Gcn4.[Gcn2] (Mus musculus) PubMed
9029.
The present paper reported that a single amino acid substitution in the mature form of Isu1 restored many deficient functions in yfh1 or frataxin-depleted yeast cells. (Mus musculus) PubMed
9030.
NS1 protein plays a role in the regulation of splicing of influenza virus M1 mRNA. [NS1, M1] (Mus musculus) PubMed
9031.
KipA is an active ATPase, which is able to dimerize and move processively along microtubules with a speed of 9.48 mum/min (Mus musculus) PubMed
9032.
Down-regulation of SBEIIb by miRNA produced a more extreme starch phenotype than hp-RNA. [SBEIIb] (Mus musculus) PubMed
9033.
the Est1-Ccq1 interaction is critical for telomerase recruitment, while the Est1-TER1 interaction acts downstream from Ccq1-mediated recruitment to stabilize the holoenzyme at the telomere [Ccq1, TER1, Est1; no strain indicated] (Mus musculus) PubMed
9034.
A total of seven single nucleotide polymorphisms were identified, two in SBD1 and five in SBD2.[SBD1] (Mus musculus) PubMed
9035.
Collectively, these data support an important role of the graRS and vraFG loci in the sensing of and response to specific cationic antimicrobial peptides involved in innate host defenses. (Mus musculus) PubMed
9036.
Results indicate that LYK3 protein localization and dynamics are altered in response to symbiotic bacteria [LYK3]. (Mus musculus) PubMed
9037.
RNA-dependent RNA polymerase and nonstructural proteins 2, 3, and 8 are incorporated into viral particles. (NSP, RdRp) (Mus musculus) PubMed
9038.
Overexpression of the truncated OsTPS1 enhances tolerance to drought, salt and cold in rice. (Mus musculus) PubMed
9039.
eri-6/7 mutations cause the loss of 26-nucleotide (nt) endogenous siRNAs derived from genes and pseudogenes in oocytes and embryos, as well as deficiencies in somatic 22-nucleotide secondary siRNAs corresponding to the same loci. [ERI-6/7] (Mus musculus) PubMed
9040.
Cg_ArsC1' is a three-cysteine containing homodimer that uses a reduction mechanism linked to the thioredoxin pathway with a k(cat)/K(M) value which is 10(3) times higher than the one of Cg_ArsC1 or Cg_ArsC2.[Cg_ArsC1', Cg_ArsC1, Cg_ArsC2] (Mus musculus) PubMed
9041.
pigment granule aggregation signals in melanophores stimulate microtubule minus end-directed transport by increasing the number of growing microtubule plus ends decorated with CLIP-170. [CLIP-170] (Mus musculus) PubMed
9042.
Clb5-Cdk1-dependent phosphorylation generates positive feedback that is required for switch-like Sic1 destruction [Sic1] (Mus musculus) PubMed
9043.
studies have revealed novel regulatory elements in Cyr1 that normally repress Cyr1 activity to prevent the toxicity of unregulated high cAMP levels. (Mus musculus) PubMed
9044.
The primary phenotype of ARP4a mutation is the mis-segregation of duplicated chromosomes with chromosome loss during nuclear division.[ARP4a] (Mus musculus) PubMed
9045.
The authors identified IPSE/alpha-1 as a novel hepatotoxin and conclude that both IPSE/alpha-1 and omega-1 account for the majority of the hepatotoxicity secreted by Schistosoma mansoni eggs.[IPSE/alpha-1] (Mus musculus) PubMed
9046.
These data further support the hypothesis that alternative oxidase is important in the fungal defense against oxidative stress imposed by immune cells and is relevant in the virulence of Paracoccidioides brasiliensis.[alternative oxidase] (Mus musculus) PubMed
9047.
The authors have identified three conserved arginine residues of IF7 and IF17 that are essential for the interaction of these proteins with glutamine synthetase type I.[IF7 and IF17] (Mus musculus) PubMed
9048.
These results show that AdcA and AdcAII play an essential and redundant role in specifically importing zinc into the pneumococcus, and that both zinc transporters are required for proper cell division and for bacterial survival during infection.[AdcAII] (Mus musculus) PubMed
9049.
Its main activity is the conversion of InsP(6) to 5PP-Ins(1,2,3,4,6)P(5), one of the main inositol phosphates found in Entamoeba histolytica.[EhIPK1] (Mus musculus) PubMed
9050.
data suggest MADS6 is a key player in specifying flower development via interacting with other floral homeotic genes in rice [MADS6] (Mus musculus) PubMed
9051.
The yeast H3 mutants hht2-T80A, hht2-K79E, hht2-L70S, and hht2-E73D show normal nucleosome positioning and stability in minichromosomes.[Histone H3] (Mus musculus) PubMed
9052.
Expression of the OmpC K12 porin in the clinical isolates lowers the microbial inhibitory concentration, consistent with modified porin function contributing to drug resistance.[OmpC] (Mus musculus) PubMed
9053.
GcvB rewires primary transcriptional control circuits and seems to act as a distinct regulatory node in amino acid metabolism. [GcvB] (Mus musculus) PubMed
9054.
expression, purification and characterization of RocF and its apo form [RocF] (Mus musculus) PubMed
9055.
crystals of SecDF diffracted X-rays to 2.3 A resolution and belonged to space group C2, with unit-cell parameters a = 161.1, b = 35.8, c = 181.6 A, suggesting that they contain four molecules per asymmetric unit (Mus musculus) PubMed
9056.
Rpn12 binds LP2 only upon correct assembly of all other lid subunits, and the Rpn12 tail then helps drive lid-base joining.(Rpn12) (Mus musculus) PubMed
9057.
The Gal11 activator-binding domain 1 has a four-helix fold with a small shallow hydrophobic cleft at its center. (GAL11 & GCN4) (Mus musculus) PubMed
9058.
Both crystals of capsid protease belonged to space group C2, with unit-cell parameters a = 79.6, b = 35.2, c = 49.5 A[capsid protease] (Mus musculus) PubMed
9059.
the contribution of phoX in poly P synthesis and in TAT-system mediated stress responses [phoX] (Mus musculus) PubMed
9060.
AKHR2a and AKHR2b are two orphan G-protein-coupled receptors for adipokinetic hormones from silkworm Bombyx mori [AKHR2a, AKRH2b] (Mus musculus) PubMed
9061.
Study demonstrates that ZfL2-1 ORF1p has all the canonical activities associated with known ORF1ps, including self-interaction, nucleic acid binding, and nucleic acid chaperone activities. [Zfl2-1 ORF1p] (Mus musculus) PubMed
9062.
Results indicate that CscB exhibits specificity directed toward the fructofuranosyl moiety of the glycoside to be transported. [CscB; sucrose permease] (Mus musculus) PubMed
9063.
a new rice (Oryza sativa L.) blast resistance allele of Pid3, designated Pi25 [Pi25] (Mus musculus) PubMed
9064.
Parasites lacking NPT1 are severely compromised in the production of gametocytes and the rare gametocytes produced are unable to differentiate into fertile gametes[NPT1] (Mus musculus) PubMed
9065.
These findings suggest that PfCRT and PfMDR1 are carriers of antimalarial drugs. (Mus musculus) PubMed
9066.
The authors show that in W65Scyc1 cells there is a decrease in reactive oxygen species production and an increase in caspase-like activity.[cyc1] (Mus musculus) PubMed
9067.
Silencing of CLSP2, but not CLSP1, results in the activation of prophenoloxidase, suggesting that CLSP2 is a negative modulator of this reaction. [CLSP1 and CLSP2] (Mus musculus) PubMed
9068.
We demonstrate that the CopA ATPase is a major pneumococcal copper resistance mechanism and provide the first evidence that the CupA protein plays a role in copper resistance. [CopA and CupA] (Mus musculus) PubMed
9069.
Characterization of the Src/Abl hybrid kinase SmTK6 of Schistosoma mansoni [SmTK6] (Mus musculus) PubMed
9070.
Mutations in cup-5, encoding the C. elegans Mucolipin 1 homolog, cause defects in the autophagy pathway.[CUP-5] (Mus musculus) PubMed
9071.
Immunomicroscopy revealed EhMLCI cortical and cytoplasmic distribution in trophozoites and true colocalization with EhmhcA.[EhMLCI] (Mus musculus) PubMed
9072.
Changes in the local DNA structure as well as in the MutS structure that appear to be correlated with base flipping, were observed.[MutS] (Mus musculus) PubMed
9073.
GlnK is a pleiotropic regulator for morphological differentiation and secondary metabolism. [GlnK] (Mus musculus) PubMed
9074.
A report on key mechanistic differences between the reverse transcriptases of human immunodeficiency virus type-1 and of xenotropic murine leukemia virus-related virus(reverse transcriptase). (Mus musculus) PubMed
9075.
These findings indicate that phytochromes contribute to multiple steps in the control of internode elongation.[PhyA, PhyB, PhyC] (Mus musculus) PubMed
9076.
FACT-L is critically involved in the formation of fertile male gametes and parasite transmission. [FACT-L] (Mus musculus) PubMed
9077.
Identification of tvMyb3(53-180) as the essential fragment for DNA recognition and a report of the crystal structure of tvMyb3(53-180) bound to MRE-1 promoter DNA (Myb3). (Mus musculus) PubMed
9078.
The findings underscore the possibility that contemporary alanyl-tRNA synthetase genes (ALA1 and ALA2)in V. polyspora arose relatively recently from duplication of a dual-functional predecessor of mitochondrial origin(ALA1 and ALA2). (Mus musculus) PubMed
9079.
Results describe and compare the expression of the neuronal nuclei protein (NeuN, a.k.a. Fox-3) and doublecortin antigens in the whole brain of chicks 2 days, 8 days, and 14 weeks posthatch [NeuN]. (Mus musculus) PubMed
9080.
Panicles of the lp-1 and lp-2 mutants show improved architecture, produce more inflorescence branches and contain more grains. [LP] (Mus musculus) PubMed
9081.
extent and frequency of allelic diversity at the Pvmsp-1 locus in field isolates in Republic of Korea during the past decade; 6 Pvmsp-1 gene types (SKOR-I to SKOR-VI) were identified as unique combinations of type sequences in each variable bloc [msp-1] (Mus musculus) PubMed
9082.
cloning and characterization of RPS29; transcriptional level of RPS29 was upregulated in deltamethrin (DM) resistant Cx. p. pallens; study provides evidence that RPS29 might be associated with fitness cost of DM resistance (Mus musculus) PubMed
9083.
Genome wide cloning of maize meiotic recombinase Dmc1 and its functional structure through molecular phylogeny. [Dmc1] (Mus musculus) PubMed
9084.
The expression of xen1 starts on a later stage of development 47-48, while the gene xen2 is expressed on all stages of development with the same increase starting from stage 0-5. [xen1] [xen2] (Mus musculus) PubMed
9085.
yeast cells control RNR function during iron deficiency by redistributing the Rnr2-Rnr4 small subunit from the nucleus to the cytoplasm [Rnr2 & Rnr4] (Mus musculus) PubMed
9086.
the importance of two invariant residues, Gln2 and Ser65 in ubiquitin (Mus musculus) PubMed
9087.
study reports that ICP0 induces the widespread proteasome-dependent degradation of SUMO-conjugated proteins during infection and has properties related to those of cellular SUMO-targeted ubiquitin ligases ICP0] (Mus musculus) PubMed
9088.
VocC is required for the efficient secretion of VopC via type III secretion system 2. [VopC] (Mus musculus) PubMed
9089.
Sapp1p displays enzyme activity prior to secretion, and therefore, it is probably fully folded within the upper layer of the cell wall. [Sapp1p] (Mus musculus) PubMed
9090.
Rice and Arabidopsis CFL1 negatively regulate cuticle development by affecting the function of HDG1, which regulates the downstream genes BDG and FDH. [HDG1; CFL1] (Mus musculus) PubMed
9091.
Nitric oxide (NO)-mediated GS posttranslational inactivation is related to metabolite channeling to boost the nodule antioxidant defenses in response to NO.[GS] (Mus musculus) PubMed
9092.
p38 MAPK signaling regulates neutrophil infiltration in acute lung injury induced in mice by streptococcal M1 protein.[M1 PROTEIN] (Mus musculus) PubMed
9093.
These findings newly indicate a regulatory role of beta and beta' subunits of CK2 in the nutrient response.[CK2 beta, CK2 beta'] (Mus musculus) PubMed
9094.
A structure for Zea mays CK2beta1 by homology modeling, is predicted.[CK2beta] (Mus musculus) PubMed
9095.
LAX2 encodes a nuclear protein that is required for the process of axillary meristem formation and acts together with LAX1. [LAX2] (Mus musculus) PubMed
9096.
complex regulatory mechanisms underlie functional matA expression during self-fertilization and sexual reproduction in A. nidulans[matA] (Mus musculus) PubMed
9097.
EspT induces expression of cyclooxygenase-2 in U937 human macrophages by activating the nuclear factor kappa-B, the extracellular signal-regulated kinases 1 and 2 (Erk1/2) and c-Jun N-terminal kinase (JNK) pathways. [EspT] (Mus musculus) PubMed
9098.
(cortisol) There was a significant increase in cortisol at birth in lambs born to obese ewes related to an increase in leptin in the first day of life. (Mus musculus) PubMed
9099.
The data of this study demonistrated that the apobec2b is essential for retina and optic nerve regeneration. (Mus musculus) PubMed
9100.
These results show the possibility that polka dots (Xpod) is involved in the establishment of a certain subpopulation of ionocytes under hypertonic conditions.[Xpod] (Mus musculus) PubMed
9101.
Depolarization-induced charge movement causes a conformational change in the M(2) receptor that may be responsible for the voltage-dependence of agonist binding.[M2R] (Mus musculus) PubMed
9102.
Rev1 is biologically relevant and is required specifically for dCMP insertion during the bypass of endogenous AP sites [Rev1] (Mus musculus) PubMed
9103.
SAGA-associated Sgf29p facilitates the recruitment of TBP (and hence transcription) without altering the global structural integrity of SAGA in vivo [Sgf29p][TBP] (Mus musculus) PubMed
9104.
The work described herein provides a platform for photochemical radical initiation and study of proton-coupled electron transfer (PCET) in the beta2 subunit of RNR.[RNR beta2] (Mus musculus) PubMed
9105.
Mph1 is a sufficient marker for recruitment of Bub1. Mad1, in contrast, requires an additional condition/component for stable association with kinetochores.[Mph1, Bub1, Mad1] (Mus musculus) PubMed
9106.
the structural basis and mechanistic implications of TLR5-flagellin recognition [flagellin] (Mus musculus) PubMed
9107.
P11 could bind to A. phagocytophilum and thus facilitate its infection of tick cells.[P11] (Mus musculus) PubMed
9108.
novel streptogramin A, pleuromutilin, and lincosamide resistance determinant, Vga(E), was identified; vga(E) gene encoded a 524-amino-acid protein belonging to the ABC transporter family [vga(E)] (Mus musculus) PubMed
9109.
The deletion of Candida glabrata genes PWP7 and AED1 results in a significant reduction in adherence to endothelial cells compared with the wild-type parent.[PWP7 and AED1] (Mus musculus) PubMed
9110.
As a consequence, the disruption of ZDS3 resulted in complete loss of virulence in a mouse cryptococcosis model.[ZDS3] (Mus musculus) PubMed
9111.
the duplication of a chromosomal segment containing mdr1 is selected by mefloquine, lumefantrine, and artemisinin from a complex P. chabaudi genetic mixture. [mdr1] (Mus musculus) PubMed
9112.
the nucleus-encoded TDA1 factor is specifically required for translation of the chloroplast atpA transcript that encodes subunit alpha of ATP synthase [TDA1] (Mus musculus) PubMed
9113.
This finding indicates that the energy required for PvuA1 to transport ferric vibrioferrin across the outer membrane is provided by the TonB2 system.[PvuA1 & TonB2] (Mus musculus) PubMed
9114.
a signal peptide is required for the assembly of a bacterial adhesin FadA [FadA] (Mus musculus) PubMed
9115.
SIZ-dependent sumoylation may modulate the activity of multiple proteins to promote efficient nucleotide excision repair [SUMO] (Mus musculus) PubMed
9116.
Srs2 promotes checkpoint recovery by removing Rad51 after DNA repair [Srs2] (Mus musculus) PubMed
9117.
a post-translational modification to the inactive enzyme during hypoxia [Sod1p] (Mus musculus) PubMed
9118.
These findings suggest that the constitutive activation of STAT6 by Tip in T-cells may contribute to IL-2-independent T-cell transformation by herpesvirus saimiri.[Tip] (Mus musculus) PubMed
9119.
These results indicate that the acylation and cholesterol-binding motifs in M2 are not crucial for the replication of influenza virus in cell culture, indicating that other factors can target M2 to the budding site.[M2] (Mus musculus) PubMed
9120.
HTLV-1 transmission through cellular conduits induced by the viral accessory protein p8. [p8] (Mus musculus) PubMed
9121.
The fibrinogen-binding protein (Fbl) of Staphylococcus lugdunensis is not involved in the invasion of cells as ruled out by an isogenic fbl mutant.[Flb] (Mus musculus) PubMed
9122.
WR1 is a positive regulator of wax synthesis related genes , and this regulation, distinct from its homology regulator of WIN1/SHN1 in cutin synthesis, subsequently contributes to reduced water loss and enhanced drought tolerance. (WR1) (Mus musculus) PubMed
9123.
[dihydrofolate reductase DHFR] Two modified 23S rRNA ribosomes suppress UAG codons in E. coli DHFR in the presence of beta-alanyl-tRNA. (Mus musculus) PubMed
9124.
These results suggest that CagA C-terminal domain EPIYA repeats directly interact with cholesterol-rich microdomains that induce efficient IL-8 secretion in the epithelial cells.[CagA] (Mus musculus) PubMed
9125.
ApbC mutant is unable to grow on tricarballylate as a carbon source. [ApbC] (Mus musculus) PubMed
9126.
new structural and functional insight into a carbohydrate-mediated component of the pneumococcus-host interaction mediated through StrH is provided. [StrH] (Mus musculus) PubMed
9127.
[RrgA; RrgB; RrgC] Sortase-2 catalyzes the formation of both RrgA-RrgB and RrgB-RrgC structural complexes. (Mus musculus) PubMed
9128.
MtlA protein expression is regulated posttranscriptionally by the MtlS small regulatory RNA.[MtlS] (Mus musculus) PubMed
9129.
Results sugggest that Ndc10 provides a central platform for inner-kinetochore assembly: [Ndc10] (Mus musculus) PubMed
9130.
Bacterial two-hybrid and far-Western analysis indicated that Mip interacted with PrtA directly.[PrtA] (Mus musculus) PubMed
9131.
the structure of IRP1 in complex with transferrin receptor 1 B iron responsive elements [IRP1] [transferrin receptor 1 B] (Mus musculus) PubMed
9132.
LytF is a functional analogue of CbpD and is an essential part of the natural transformation system.[LytF] (Mus musculus) PubMed
9133.
Vimentin- like transcript was expressed in both chordocytes and chordoblasts, whereas the elastin- like transcript was uniquely expressed in the chordoblasts lining the notochordal sheath.[Elastin] (Mus musculus) PubMed
9134.
Using molecular dynamics simulations, the catalytic roles of Arg197 and Thr183 were analyzed. [sortase A] (Mus musculus) PubMed
9135.
VanN-type resistance was transferable by conjugation to E. faecium. This is the first report of transferable D-Ala-D-Ser-type resistance in E. faecium. [VanN] (Mus musculus) PubMed
9136.
Telomerase regulatory subunit Est3 in Candida species physically interacts with the TEN domain of TERT and telomeric DNA [Est3, TRT1] (Mus musculus) PubMed
9137.
anthoMATE1 and anthoMATE3 are involved in anthocyanin transport mechanisms.[anthoMATE3, anthoMATE1] (Mus musculus) PubMed
9138.
The phosphotransferase VanU, which phosphorylates and activates VanO, repressed expression of the Qrr sRNAs and stabilized vanT mRNA.[VanU, VanO and Qrr] (Mus musculus) PubMed
9139.
ROP is the first example of a zinc finger transcription factor involved in the catabolite repression of phosphoenolpyruvate carboxykinase in yeast cells cultured under biotin- or PC-deficient and glucose-abundant conditions.[ROP] (Mus musculus) PubMed
9140.
Xog1p is one of the LL37/hBD-3 targets, and elevated beta-1,3-exoglucanase activity reduces C. albicans adhesion to plastic.[Xog1p ; candida albicans.] (Mus musculus) PubMed
9141.
The crystal RrgB fibre is a compelling model for deciphering the molecular details required to generate the pneumococcal pilus. (Mus musculus) PubMed
9142.
chloroplast preproteins as a general class of HSP90 client proteins in plants using HOP and FKBP as novel cochaperones [HSP90][FKBP][HOP] (Mus musculus) PubMed
9143.
OsGL1-1 is involved in leaf cuticular wax and cuticle membrane [OsGL1-1] (Mus musculus) PubMed
9144.
Results suggest a possible mechanism for ATP-dependent DNA tethering and DNA double-strand break processing by the Mre11:Rad50 complex (MRE11, Rad50). (Mus musculus) PubMed
9145.
Although Dcp2 can interact with Upf1, this interaction is indirect and is largely dependent on the Edc3 protein, which interacts with the N-terminal domain of Upf1 and Pat1 has an independent interaction with the N-terminus of Upf1.[Upf1, Edc3, Pat1] (Mus musculus) PubMed
9146.
proteotoxic stress, caused by transient Hsp90 inhibition or heat shock, markedly increased chromosome instability to produce a cell population with high karyotype diversity [Hsp82] (Mus musculus) PubMed
9147.
interaction between Gal3p-Gal80p proteins occurs only when Gal3p is in a "closed" state induced by ligand binding[Gal3 and Gal80; strain not listed] (Mus musculus) PubMed
9148.
Heptatitis c virus (HCV) specific E2 and host CD81 antibodies reduce HCV pseudoparticle entry.[E2] (Mus musculus) PubMed
9149.
Candida glabrata Yps1 is required for cell growth at elevated temperatures, and that the heat-induced expression of YPS1 is regulated predominantly by the calcineurin-Crz1 pathway and partially by the Slt2 MAPK pathway. [YPS1, CRZ1, and SLT2] (Mus musculus) PubMed
9150.
Both slnA and drkA are essential for the generation of yeast cells in vivo, with slnA required for the germination of conidia and drkA required for dimorphic switching during macrophage infection.[slnA and drkA] (Mus musculus) PubMed
9151.
the direct phosphorylation of Ccq1 Thr 93 by Tel1 and Rad3 is involved in the recruitment of telomerase to elongate telomeres [Tell(ATM), Rad3(ATR), Ccq1;different strain] (Mus musculus) PubMed
9152.
crystal structure of a botulinum neurotoxin (BoNT/A)in complex with nontoxic nonhemagglutinin(NTNHA) protein at 2.7 A; studies show NTNHA provides large and multivalent binding interfaces to protect BoNT/A from gastrointestinal degradation [BoNT/A; NTNHA] (Mus musculus) PubMed
9153.
identified gene inducing male-specific wing size and shape differences between species; results indicate how changes in regulation of upd-like are involved in microevolution of morphologic and sex-specific differences between species[upd-like NV21594] (Mus musculus) PubMed
9154.
These results highlight that in tissue culture, function of elongation factor G in the apicoplast can be diminished, but during an animal infection, translation in the apicoplast must be fully functional.[elongation factor G] (Mus musculus) PubMed
9155.
We show that the syntenic A. gossypii homolog of MFa1 (AFL062w) does not encode a mature a-factor peptide, but identified another gene, AAR163c, which encodes a candidate a-specific mating pheromone and is thus reannotated as AgMFalpha2. [AgMFalpha2] (Mus musculus) PubMed
9156.
The regulation of copper homeostasis by Cuf1 is realized by its subcellular localization.[Cuf1] (Mus musculus) PubMed
9157.
As anticipated, deletion of ccpA derepressed tricarboxylic acid cycle activity and inhibited biofilm formation; however, ccpA deletion had only a modest effect on icaADBC transcription.[ccpA] (Mus musculus) PubMed
9158.
crystals of dextranase diffracted to a resolution of 1.6 A and belonged to space group P2(1), with unit-cell parameters a = 53.2, b = 89.7, c = 63.3 A, beta = 102.3 degrees [dextranase] (Mus musculus) PubMed
9159.
crystals of Serine-rich repeat protein 1 diffracted to 3.8 A resolution using synchrotron radiation and belonged to space group P2(1), with unit-cell parameters a = 47.56, b = 59.48, c = 94.71 A, beta = 93.95 degrees [Serine-rich repeat protein 1] (Mus musculus) PubMed
9160.
Identification of the key residues, His121, Asn145 and Glu164, which are crucial for Spd1 nucleolytic activity (Spd1). (Mus musculus) PubMed
9161.
CgArsR-C15/16/55S was expressed, purified, crystallized and X-ray diffraction data were collected to 1.86 A resolution[CgArsR-C15/16/55S] (Mus musculus) PubMed
9162.
crystals of 130K replication protein belonged to the orthorhombic space group P2(1)2(1)2(1), with unit-cell parameters a = 85.8, b = 128.3, c = 40.7 A.[130K replication protein] (Mus musculus) PubMed
9163.
The collective findings of this study provide insight into the regulation of the bamboo mosaic virus satellite RNA (satBaMV)-P20 ribonucleoprotein complex by phosphorylation during satBaMV co-infection (P20). (Mus musculus) PubMed
9164.
the expression of igf-I, gh and ghr1 is involved in the regulation of growth rate at larval stages in T. rubripes [growth hormone, growth hormone receptor I and insulin-like growth factor I] (Mus musculus) PubMed
9165.
the mechanism of GUN4 activation of magnesium chelatase [GUN4][Ch1H] (Mus musculus) PubMed
9166.
Thus, Trichomonas vaginalis pyruvate:ferredoxin oxidoreductase A (PFOA) is an example of a surface-associated cell-binding protein that lacks enzyme activity and that is involved in cytoadherence.[pfoA] (Mus musculus) PubMed
9167.
Mutations in the core region and NS5A region of hepatitis C virus are associated with peginterferon responsiveness in chronic hepatitis C. (Mus musculus) PubMed
9168.
Deletion of PGA26 may cause an imbalance in the morphological switching ability of Candida, leading to attenuated dissemination and infection. [PGA26] (Mus musculus) PubMed
9169.
H3 tail acts as an integrating platform for signals that influence DNA methylation, in part through methylation of H3K9.[histone H3] (Mus musculus) PubMed
9170.
cholesterol impedes the membrane association and destabilizing activities of membrane-proximal external region of gp41.[gp41] (Mus musculus) PubMed
9171.
The free energy barrier for water-mediated proton transport between the two proton gating residues Glu(203) and Glu(148) in the ClC-ec1 antiporter, including the Grotthuss mechanism of proton hopping, was calculated.[ClC-ec1] (Mus musculus) PubMed
9172.
A basal signalling module providing activation of Ras at the leading edge, which is sufficient for chemotaxis, was identified.[Ras] (Mus musculus) PubMed
9173.
TTV ORF1 protein may be a nuclear protein which contains 2 non-regular secondary structure region. 265aa to 486aa and 510aa to 679aa may be the two fragments to construct the plasmids, which would be prepared for future hybrid experiments [ORF1 protein] (Mus musculus) PubMed
9174.
miR-449 strongly accumulated in multiciliated cells in human airway epithelium and Xenopus laevis embryonic epidermis, where it triggered centriole multiplication and multiciliogenesis by directly repressing the Delta/Notch pathway.[review: miR-449] (Mus musculus) PubMed
9175.
Ole1 (fatty acid desaturase) regulates glucotoxicity by converting glucose into lipid droplets. [Ole1] (Mus musculus) PubMed
9176.
PbP27 expression was examined at the transcriptional and translational levels in the mycelia and yeast forms of different isolates of the species complex of P. brasiliensis (PbP27). (Mus musculus) PubMed
9177.
Pob3 histone binding was modification-independent, implicating the loop of Rtt106 in H3K56ac-specific recognition in vivo.[Rtt106] (Mus musculus) PubMed
9178.
Structures of the central domain in two different oligomerization states for a small terminase from the T4 family of phages, are reported.[Terminase] (Mus musculus) PubMed
9179.
Analysis of the data elucidated a new role of NCp7 by facilitating DNA-directed DNA synthesis during reverse transcription by HIV-1 reverse transcriptase. [NCP7 protein, HIV-1] (Mus musculus) PubMed
9180.
The hSIK1 appears to be of potential relevance within vascular smooth muscle cells function and blood pressure regulation. (Mus musculus) PubMed
9181.
FliC could enhance specific IgA responses in saliva and protective ability of pGJA-P VAX, providing an effective mucosal adjuvant candidate for intranasal immunization of an anti-caries DNA vaccine [FliC] (Mus musculus) PubMed
9182.
The protein encoded by hemN1 appears to be the major enzyme that is involved in anaerobic heme synthesis of Shewanella oneidensis.[hemN1] (Mus musculus) PubMed
9183.
A predicted basic helix-loop-helix protein-encoding gene designated ecdR (early conidiophore development regulator) plays a major role in conidiation in Aspergillus oryzae(ecdR). (Mus musculus) PubMed
9184.
Findings indicate that multicilin initiates multiciliate cell differentiation in diverse tissues, by coordinately promoting the transcriptional changes required for motile ciliogenesis and centriole assembly [multicilin] (Mus musculus) PubMed
9185.
Using limited proteolysis coupled with mass spectrometric analyses, the authors defined CheA(163-256) to be the CheS binding domain, which overlaps with the N-terminal part of the CheY2 binding domain (CheA(174-316)).[CheA & CheS] (Mus musculus) PubMed
9186.
The authors propose a model for RpoS regulation of motility gene expression that involves (i) attenuation of H-NS repression by IHF and (ii) RpoS-dependent transcription initiation resistant to H-NS.[RpoS & H-NS] (Mus musculus) PubMed
9187.
This study aimed at gainin an enhanched view of ion binding to the extraceullular end of the KcsA ion channel selectivity filter.[KcsA] (Mus musculus) PubMed
9188.
The transition state structure is able to descend down the glycosylation pathway through the critical combination of Asp214 (HOMO), ring oxygen (LUMO), and Glu212 (HOMO), anomeric carbon (LUMO) interactions. [cellobiohydrolase I] (Mus musculus) PubMed
9189.
Accordingly, inactivation of yjbH in Staphylococcus aureus increased the level of Spx protein and transcription of the Spx-regulated gene trxB.[yjbH] (Mus musculus) PubMed
9190.
Here the authors present evidence that bistable expression of the type 1 pilus is mediated by the positive-feedback loop controlling rlrA expression.[rlrA] (Mus musculus) PubMed
9191.
we report the identification of a nuclear localization domain in Myb2, spanning nearly the entire R2R3 domain. [Myb2] (Mus musculus) PubMed
nuclear pore complex mediates binding of the Mig1 repressor to target promoters [Mig1] (Mus musculus) PubMed
9194.
We identify the ssDNA-binding protein, I3 as a viral factor that interacts and co-localizes with the eIF4F scaffold protein, eIF4G in VACV infected cells. [I3] (Mus musculus) PubMed
9195.
TRAIL dependent fratricidal killing of gp120 primed hepatocytes by HCV core expressing hepatocytes (Mus musculus) PubMed
9196.
The target-of-rapamycin (TOR) growth pathway modulates cilia size and function during zebrafish development.[Torc1] (Mus musculus) PubMed
9197.
The FusB family are two-domain metalloproteins, the C-terminal domain of which contains a four-cysteine zinc finger with a unique structural fold.[FusB] (Mus musculus) PubMed
9198.
Residues that confer differences in substrate specificity between Drs2 and Dnf1, Saccharomyces cerevisiae P4-ATPases that preferentially flip phosphatidylserine and phosphatidylcholine (PC), respectively, were identified.[Drs2, Dnf1] (Mus musculus) PubMed
9199.
tra1 alleles that are selectively defective for interaction with Gal4 in vivo [Gal4 interaction defective (GID) mutants], were characterized.[Gal4, Tra1] (Mus musculus) PubMed
9200.
cryo-electron microscopy reconstructions of eukaryotic and archaeal ribosome recycling complexes containing ABCE1 and the termination factor paralogue Pelota [Rli1 & Dom34] (Mus musculus) PubMed
9201.
Crystal structures of two bacterial E3s, Salmonella SopA and Escherichia coli NleL, both in complex with human E2 UbcH7, are reported.[NleL] (Mus musculus) PubMed
9202.
The pathogenicity of eaeA was moderate attenuated and the pathogenicity of stx2 and ehxA were highly attenuated. [Stx2,eaeA ] (Mus musculus) PubMed
9203.
Rhcg1 and NHE3b are involved in ammonium-dependent sodium uptake by zebrafish larvae acclimated to low-sodium water. (Mus musculus) PubMed
9204.
a mutation in the acceptor site of the second intron of SV2A (the gene encoding synaptic vesicle glycoprotein 2A) is causing photosensitive reflex epilepsy in a unique vertebrate model, the Fepi chicken [SV2A] (Mus musculus) PubMed
9205.
XIAP may act as a regulator of follicular atresia in the sheep ovary by preventing activation of caspase 3. [XIAP] (Mus musculus) PubMed
9206.
findings suggest that although the hemagglutinin D222G mutation does not influence virus transmission, it may be considered a molecular marker for enhanced replication in certain cell types[HA] (Mus musculus) PubMed
9207.
Cj0561c was more effectively induced by bile salts than cmeABC and taurocholate was superior to cholate as an inducer of transcription. [Cj0561] (Mus musculus) PubMed
9208.
Edc3 & Scd6 stimulate decapping in vitro, presumably by preventing the Dcp1:Dcp2 complex from adopting an inactive conformation. Protein interactions via LSm & HLM domains were identified.[Scd6] (Mus musculus) PubMed
9209.
(neuron-specific enolase) No correlation is found between neuron-specific enolase (NSE) levels and outcome following spinal cord decompression. The initial degree of paresis is not a prognostic factor to predict outcome. (Mus musculus) PubMed
9210.
preventing gadd153 activation protects against Alzheimer's disease related to cholesterol oxidized products.[GADD153] (Mus musculus) PubMed
9211.
in trout embryo, N-cadherin is associated with muscle cell immaturity while M-cadherin is associated with muscle cell maturation and differentiation and this during the two successive phases of myogenesis [n-cadherin, M-cadherin] (Mus musculus) PubMed
9212.
These data suggest that the ClpXP adaptor YjbH has more target proteins than previously thought, and that oxidative burst and beta-lactam resistance mechanisms of S. aureus are closely linked. [YjbH] (Mus musculus) PubMed
9213.
Results showed that SatAB is a narrow-spectrum fluoroquinolone exporter (norfloxacin and ciprofloxacin), susceptible to reserpine,esistance. [SatA, SatB, SmrA] (Mus musculus) PubMed
9214.
Expression levels of MYB genes (MYB13-1, MYB13-2 and MYB13-3) were found to be positively correlated with the mRNA levels of sucrose:sucrose 1-fructosyltransferase and sucrose:fructan 6-fructosyltransferase in wheat stems.[MYB13-1] (Mus musculus) PubMed
9215.
OsNST1 is important for the overall structure of cell wall polysaccharides. Mutants show altered orientation of cellulose microfibrils. (Mus musculus) PubMed
9216.
This study supports the involvement of the Pfnhe-1 gene in the modulation of the in vitro quinine response when associated with mutated Pfcrt and Pfmdr1 genes.[nhe-1] (Mus musculus) PubMed
9217.
Ligustrazine has notable protective effects on pulmonary ischemia/reperfusion injury inhibiting Fas/FasL mRNA express in lung tissue and decreasing apoptosis. (Mus musculus) PubMed
9218.
These results demonstrate that ggFcR has a contact site to IgY which closely resembles that of human IgG bound to FcR.[ggFcR, IgY] (Mus musculus) PubMed
9219.
The presence of jhp0945 was significantly associated with gastric ulcer, duodenal ulcer, and gastric cancer (odds ratios [95% confidence intervals]: 2.27 [1.04 to 4.98], 1.86 [1.03 to 3.34], and 1.92 [1.03 to 3.56], respectively).[jhp0945] (Mus musculus) PubMed
9220.
The fusB resistance determinant in S. epidermidis was highly associated with phage-related resistance islandss. [Fus] (Mus musculus) PubMed
9221.
The first direct observation of the interaction between chemoreceptor and CheW.{CheW] (Mus musculus) PubMed
9222.
conserved element in RNA polymerase II promoters [RNA polymeras II] (Mus musculus) PubMed
9223.
A lack of gp180 encoded by Bo10 had no impact on the establishment and maintenance of BoHV-4 latency, but markedly sensitized virions to neutralization by immune sera[Bo10] (Mus musculus) PubMed
Solution structure of the HIV-1 exon splicing silencer 3.[ ESS3 (Exon splicine silencer 3); HIV-1] (Mus musculus) PubMed
9226.
N-terminally myristoylation of Gag allows Env-independent budding of viral particles. (Mus musculus) PubMed
9227.
[heat-labile enterotoxin B] A hybrid peptide of E coli enterotoxin B subunit fused with synapsin carboxyl domain up-regulates expression of anti-inflammatory cytokines and diminishes myelin basic protein-specific T-helper cell responses in lymph nodes. (Mus musculus) PubMed
9228.
These results show that the XylB, RbtT, and MtlD proteins allow the growth of Corynebacterium glutamicum on D-arabitol and that D-arabitol metabolism is subject to arabitol-dependent derepression by AtlR.[AtlR] (Mus musculus) PubMed
GAL102 in C. albicans encodes a homolog of dTDP-glucose 4,6-dehydratase, an enzyme that affects cell wall properties as well as virulence of many pathogenic bacteria[Gal102] (Mus musculus) PubMed
9231.
GF14e-silenced plants show enhanced resistance to bacterial and fungal rice diseases. [GF14e] (Mus musculus) PubMed
9232.
MSP1-19 is not a major target of growth inhibitory antibodies [MSP1] (Mus musculus) PubMed
9233.
the specificity of NEDD8-specific peptidase SENP8 [NEDD8] (Mus musculus) PubMed
9234.
We biochemically characterized a heat stable PulA produced from T. neapolitana by examining its substrate specificity and its mode of action in transglycosylation reactions. [PulA] (Mus musculus) PubMed
9235.
WbaP (UDP-galactose:Und-P galactose-1-phosphate transferase) C-terminal domain contains all the essential motifs to catalyze the synthesis of the Und-P-P-Gal molecule that primes the biosynthesis of bacterial surface glycan (Mus musculus) PubMed
9236.
A crl5 ral1 double mutant displayed an additive phenotype, showing that the formation of each root is regulated by different genetic mechanisms in rice. [CRL5] (Mus musculus) PubMed
Radix astragali injection inhibits fibroblast proliferation in hypertrophic scars through down-regulating mRNA expression and protein synthesis of TGF-beta and Smad3. [Smad3] (Mus musculus) PubMed
9239.
the kinetics of transient events in Saccharomyces cerevisiae RFC-catalyzed PCNA loading, including ATP-induced RFC activation, PCNA opening, ptDNA binding, ATP hydrolysis, PCNA closing, and PCNA.ptDNA release.[RFC protein] (Mus musculus) PubMed
9240.
ATP binding and hydrolysis switch RFC between conformations with high and low affinities, respectively, for open PCNA and ptDNA, and thus bookend the clamp loading reaction.[RFC protein] (Mus musculus) PubMed
9241.
The study reports a real-time measurement of ATP-induced conformational changes in the terminase of bacteriophage T7. [terminase] (Mus musculus) PubMed
9242.
This study provides insight into the structure and function of the CBM33 family of enzymes, which, together with their fungal counterpart called GH61, currently receive considerable attention in the biomass processing field.[EfCBM33A enzyme] (Mus musculus) PubMed
9243.
These crystal structures depicted that DrRRA has the structural features of the OmpR/PhoB subfamily and were also confirmed by SAXS investigation of the protein in solution. [DrRRA] (Mus musculus) PubMed
9244.
These results suggest an ancestral role for TGA1-like genes in early spikelet development.[TGA1] (Mus musculus) PubMed
9245.
metacaspase-3 was biochemically validated as a bona fide SUMOylation substrate in Trypansosoma cruzi (Mus musculus) PubMed
9246.
The data provide evidence for the biological function of OsARF12, which is implicated in regulating root elongation.[OsARF12] (Mus musculus) PubMed
we describe the identification and characterization of a novel open reading frame (ORF4) encoded by the murine norovirus and propose the name virulence factor 1, VF1 for this protein (Mus musculus) PubMed
9249.
studies supported the role of Ada2 in the direct regulation of capsule and mating responses [Ada2] (Mus musculus) PubMed
9250.
aim of this work was to investigate the role of a unique sterol-sensing domain-containing protein, TgNCR1, expressed by T. gondii (Mus musculus) PubMed
9251.
clearance of sumoylated Gcn4 requires the protein kinase and Mediator complex subunit Srb10 [Gcn4 and Srb10, strain not found] (Mus musculus) PubMed
9252.
Using Colocalization single-molecule spectroscopy was used to directly visualize on single DNA molecules all major steps in initiation, including polymerase binding, open complex formation, transcript production, and sigma54 departure. [sigma 54] (Mus musculus) PubMed
9253.
found that Ndt80p directly regulated its target genes, such as YHB1, via the mid-sporulation element [Ndt80p] (Mus musculus) PubMed
9254.
PfAlba3 binds to the telomeric and subtelomeric regions as well as to var gene promoter (PfAlba3). (Mus musculus) PubMed
9255.
mutation of 3 of the 275 residues in Lhp1 alters its import pathway to a Kap121-dependent process [Lhp1][Kap121] (Mus musculus) PubMed
9256.
insight into the complexity of Hsp60 function [Hsp60] (Mus musculus) PubMed
9257.
Rf2 encodes a protein consisting of 152 amino acids with a glycine-rich domain. Expression of Rf2 mRNA was detected in developing and mature anthers. An RF2-GFP fusion was shown to be targeted to mitochondria [Rf2] (Mus musculus) PubMed
9258.
Alcohol promotes the myocardial oxidative stress and fibrosis through an elevated expression of PYK2 and a lowered expression of caveolin-1. [PYK2] (Mus musculus) PubMed
9259.
analysis reveals how the structure responds to linker separation and suggests a mechanism of MotB activation that entails linker unfolding and rotational displacement of MotB transmembrane helices[MotB] (Mus musculus) PubMed
9260.
Thermus thermophilus L1 mutant lacking one residue in the fragment corresponding to the hinge was obtained and its crystal structure was solved[ribosomal L1 protein] (Mus musculus) PubMed
9261.
structure of the complex revealed a GGDEF-domain of diguanylate cyclase dimer cross-linked by two molecules of c-di-GMP at the strongly conserved active sites[diguanylate cyclase ] (Mus musculus) PubMed
9262.
protein fold is dominated by an eight-stranded beta-sandwich and identifies SmLip as a new member of the transthyretin family of proteins[ Lip] (Mus musculus) PubMed
9263.
These results indicate that V. vulnificus AphB is involved in the IL-8 production via an NF-kappaB dependent pathway in human intestinal epithelial cells.[AphB] (Mus musculus) PubMed
9264.
crystal structure of O-Acetylhomoserine sulfhydrylase(MetY) determined at 2.2 A; structure of MetY, together with biochemical data, provides insight into mechanism of sulfur transfer to a small molecule via a protein thiocarboxylate intermediate [MetY] (Mus musculus) PubMed
9265.
It was concluded that two amino acids in avian-origin PB1, 473V and 598P, contribute to the polymerase activity of the H5N1 virus, especially in mammalian cells. (Mus musculus) PubMed
9266.
hMR expressed by vaginal epithelial cells has high affinity for HIV gp120 and this binding induces production of matrix metalloproteinases.[gp120] (Mus musculus) PubMed
9267.
Transcriptional regulation of genes encoding rice 60S ribosomal protein L32 (rpL32) in response to salt stress has been studied.[rpL32] (Mus musculus) PubMed
9268.
These data provide compelling biochemical evidence for a P(5A)-type Cta4 ATPase as an essential component of Ca(2+) transport system.[Cta4p] (Mus musculus) PubMed
9269.
purification and characterization of phenol monooxygenase; enzyme requires NADH and FAD as cofactors, catalyses hydroxylation of a wide range of monocyclic phenols, aromatic acids and dihydroxylated derivatives of benzene except for catechol (Mus musculus) PubMed
9270.
miR-BHRF1-1 is involved in TPA-induced accumulation of EBV lytic proteins and viral copies in late lytic cycle (miR-BHRF1-1). (Mus musculus) PubMed
The amino-terminal signal peptide of Vfr protein negatively influences RopB-dependent SpeB expression and attenuates virulence.[Vfr, RopB, SpeB] (Mus musculus) PubMed
9273.
The 2.0 A resolution structure of Zn(II)-bound AdcR reveals a highly helical two-fold-symmetric dimer with two distinct metal-binding sites per protomer. [AdcR] (Mus musculus) PubMed
9274.
In Cfr and RlmN, S-adenosylmethionine bound to the unique iron of the [4Fe-4S] cluster displays 2 reactivities; serves to methylate C338 or to generate the 5'-deoxyadenosyl 5'-radical, required for substrate-dependent methyl synthase activity.[Cfr] (Mus musculus) PubMed
9275.
crystal structure of Cel5A resolved to 2.05 A [Cel5A] (Mus musculus) PubMed
9276.
cloned the gene for CXCLC; results indicate that CXCLC attracts adjacent cells to the midline region, so as to ensure accurate lateral-medial directional tissue convergence during gastrulation and neurulation [CXCLC] (Mus musculus) PubMed
9277.
In contrast, a deficiency of the Treponema denticola major outer sheath protein increased resistance to LL-37.[major outer sheath protein] (Mus musculus) PubMed
9278.
This study has also shown significantly lower disease burden in Gambians infected with a mixture of cag-positive and cag-negative strains.[cagA] (Mus musculus) PubMed
9279.
These results uncovered extensive connections between Hsp90 and (1) general transcription, (2) ribosome biogenesis and (3) GTP binding proteins.[Hsp90] (Mus musculus) PubMed
9280.
the GAS surface adhesin Scl1 may have an important role in biofilm-associated pathogenicity.[sCL1] (Mus musculus) PubMed
9281.
Spodoptera frugiperda (fall armyworm) larvae fed samples of both Mp708 and Tx601 Zea mays genotypes showed high transcript number of tps23, the gene responsible for the synthesis of (E)-beta-caryophyllene in maize.[terpene synthase 23] (Mus musculus) PubMed
9282.
OsMGH3 was characterized by overexpression and knock-down analysis and a partial overlap in these phenotypes with that of mutants in OsMADS1 and OsMADS6, was shown.[OsMGH3, OsMADS1, OsMADS6] (Mus musculus) PubMed
9283.
OsCYP96B4 might be involved in lipid metabolism and regulate cell elongation.[OsCYP96B4] (Mus musculus) PubMed
9284.
FgVeA plays a critical role in a variety of cellular processes in F. graminearum.[FgVeA] (Mus musculus) PubMed
9285.
Csc1p is required for the dephosphorylation of the septation initiation network scaffolding protein Cdc11p and is thereby required for the recruitment of Byr4p, a component of the GTPase-activating subunit for Spg1p, to the mitotic spindle pole bodies. (Mus musculus) PubMed
9286.
C1d and primary ciliary dyskinesia protein 1(Pcdp1)coordinate the activity of specific dynein isoforms to control ciliary motility [C1d][primary ciliary dyskinesia protein 1] (Mus musculus) PubMed
9287.
the first incidence of Rem2 isoforms in a species that are the result of gene duplication.[Rem2] (Mus musculus) PubMed
9288.
An unprecedented subdomain in the ATP-grasp module of GshF was identified at the interface of the GshF dimer, which is poised to mediate intersubunit communication and allosteric regulation of enzymatic activity. [GshF protein] (Mus musculus) PubMed
9289.
a model for an Hsp90-Tah1-Pih1 ternary complex [Hsp90][Tah1][Pih1] (Mus musculus) PubMed
9290.
the early spliceosomal association of Bud31 [Bud31][Ycr063w] (Mus musculus) PubMed
9291.
The charged linker, in addition to providing the flexibility necessary for Hsp90 domain rearrangements--likely its original purpose--has evolved in eukaryotes to serve as a rheostat for the Hsp90 chaperone machine.[HSP90] (Mus musculus) PubMed
9292.
A rad53 mutation that destabilized the Asf1-Rad53 complex and increased the viability of rad9 and rad24 mutants in conditions of genotoxic stress, was identified.[Rad53, Asf1] (Mus musculus) PubMed
9293.
The pc4 induced foliar necrosis and supported the viral long-distance movement. [pc4] (Mus musculus) PubMed
9294.
changes within the active site of TfGH11 lead to significant differences compared with those of previously deposited Xyn11 structures via the introduction of three water-mediated hydrogen bonds when compared with the known xylanase structures [GH11] (Mus musculus) PubMed
9295.
Mbs1 promoted production of melanin and capsule and thereby was required for full virulence of C. neoformans. [Mbs1] (Mus musculus) PubMed
9296.
Candida albicans cells lacking the SUR7 gene were more susceptible to attack by macrophages than cells with the gene and showed greatly reduced virulence in a mouse model of systemic infection.[SUR7] (Mus musculus) PubMed
9297.
crystal of orotate phosphoribosyltransferase exhibited tetragonal symmetry, belonging to space group P4(1) or P4(3), with unit-cell parameters a = b = 49.15, c = 226.94 A [orotate phosphoribosyltransferase ] (Mus musculus) PubMed
9298.
hese results provide the first example of involvement of the protein N-terminal acetyltransferase in the circadian rhythm.[Nat3] (Mus musculus) PubMed
9299.
Cloning, sequencing and analysis of IL-6Ralpha and gp130 in rainbow trout and comparision with other predicted fish homologues (IL-6Ralpha and glycoprotein-130). (Mus musculus) PubMed
9300.
These results demonstrate that Toxoplasma gondii serine protease inhibitor 1 influences both parasite virulence and bradyzoite differentiation, presumably by inhibiting parasite and/or host serine proteases.[serine protease inhibitor 1] (Mus musculus) PubMed
9301.
The bleaching signal transduction pathway via NblS is regulated by RpaB and that SrrA is partially involved.[Nbls, RpaB, SrrA] (Mus musculus) PubMed
