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GeneWiki Entries

GeneWiki enables you to enrich the annotation of genes and transcripts. Please submit or edit a GeneWiki note (500 characters max) related to a gene, its transcripts, or proteins. When possible include PubMed identifiers or web resource links (URL addresses). Please ensure that the additions will have widespread use. For additional information, check the GeneWiki help document.

GeneWiki for NEWENTRY:

GeneNetwork:
 There is no GeneWiki entry for this gene.
GeneRIF from NCBI:
 1.

nleA is involved in the ability of bacteria to transmit between hosts. (Mus musculus) PubMed

 2.

Facilitation of bone marrow transplantation is dependent on facilitating cell (FC) expression of a unique heterodimer consisting of the T cell receptor beta-chain and a 33-kDa protein, FCp33. (FCp33) (Mus musculus) PubMed

 3.

developmental expression of vitamin K-dependent gamma-carboxylase activity in zebrafish embryos and effect of warfarin [vitamin K-dependent carboxylase] (Mus musculus) PubMed

 4.

Tbx5 and Wnt2b function together to initiate and specify forelimb outgrowth and identity.Tbx5 functions downstream of WNT signaling to regulate Fgf10, which, in turn, maintains Tbx5 expression during limb outgrowth [WNT-2B, FGF-10] (Mus musculus) PubMed

 5.

mib interacts with the intracellular domain of Delta to promote its ubiquitylation and internalization; mib is essential for efficient activation of Notch signaling by Delta [mind bomb mib] (Mus musculus) PubMed

 6.

zCRY and zPER2 regulate the sub-cellular distributions of zBMAL3 (BMAL3). (Mus musculus) PubMed

 7.

molecular cloning, expression, and functional characterization of zebrafish SULT1 ST1 and SULT1 ST2 [SULT1 ST1/SULT1 ST2] (Mus musculus) PubMed

 8.

Sema4E is repulsive for facial and gill motor axons and functions as a barrier for these axons within the pharyngeal arches. (sema4E) (Mus musculus) PubMed

 9.

Results suggest that the reg6 mutation causes defects in branch formation and/or angiogenic sprouting [reg6]. (Mus musculus) PubMed

 10.

the zebrafish prepro-ORX gene had one exon in contrast to mammals; The ORX-A peptide was less conserved than the ORX-B peptide compared with other vertebrates. Organization of the ORX system of zebrafish was similar to that of mammals [Prepro-orexin] (Mus musculus) PubMed

 11.

The peak absorption spectrum (lambdamax) of the zebrafish blue visual pigment is consistently shifted to short wavelength compared with that of the goldfish (blue opsin) (Mus musculus) PubMed

 12.

a novel family of parasitation-induced -RFamide neuropeptides that inhibit the activity of neuroendocrine cells in Lymnaea stagnalis. (Mus musculus) PubMed

 13.

Zebrafish possess a rhodopsin-porphyropsin interchange system that functions to spectrally tune rod and cone photoreceptors. (Rhodopsin) (Mus musculus) PubMed

 14.

role for the dazed gene in rod and Muller cell development and overall retinal cell survival and maintenance [dazed] (Mus musculus) PubMed

 15.

nephrin-positive glomeral nexus does form anteriorly and links the two structures from stage 38 onward (Mus musculus) PubMed

 16.

membrane-type 1 metalloproteinase (MT1-MMP), gelatinase A, and tissue inhibitor 2 of metalloproteinases mRNA transcripts were expressed in the blastema [MT1-MMP] (Mus musculus) PubMed

 17.

This work supports the hypothesis that Homer is an important molecule in neuronal circuit development, necessary for crucial behaviors required for development and survival.(Homer 1c) (Mus musculus) PubMed

 18.

The Proto-Oncogene Proteins b-myb is a ubiquitously expressed transcription factor involved in cellular proliferation and cancer. (Mus musculus) PubMed

 19.

aryl acylamidase associated with acetylcholinesterase was higher than the esterase activity on zebrafishembryo [aryl acylamidase] (Mus musculus) PubMed

 20.

The production of loss-of-function models for znfl2, znfl2b and znfl2/znfl2b together suggested that these erythrocyte specific zinc finger genes are dispensible for erythropoiesis. (finger-like gene 2b) (Mus musculus) PubMed

 21.

Alpha1T-expressing Muller glia dedifferentiate and mediate regeneration of the injured zebrafish retina. (Alpha1 tubulin) (Mus musculus) PubMed

 22.

Zebra fish foxl1 is a novel regulator of neural development that acts by suppressing shh expression. (Mus musculus) PubMed

 23.

zCaMKP-N plays a crucial role in the early development of zebrafish.[zCaMKP-N] (Mus musculus) PubMed

 24.

integrity of the N-terminal region and the first armadillo repeat are necessary and sufficient for high-affinity phosphorylation by CK1 of Ser-45[protein kinase CK1] (Mus musculus) PubMed

 25.

Here we further demonstrated that zebrafish Mib and Mib2, similar to their mouse orthologs, have a C-terminal-most RING finger-dependent E3 ubiquitin ligase activity. Mib and Mib2 are reciprocal E3 ubiquitin ligases and substrates. (Mus musculus) PubMed

 26.

propose a critical role for Baf60c in Notch-dependent transcription and left-right asymmetry[Baf60c] (Mus musculus) PubMed

 27.

GST Pi plays role in the detoxification mechanism of freshwater fishes (Mus musculus) PubMed

 28.

The expression of the four DrPcdh subclusters was analysed and DrPcdh transcripts are upregulated in the developing zebrafish nervous system. (Mus musculus) PubMed

 29.

Danio rerio appears to be a suitable model to gain insight into the basic physiological functions of meprin metalloproteases[ meprin alpha2] (Mus musculus) PubMed

 30.

Syntenin binding to Delta1 plays a dual role in promoting intercellular adhesion and regulating Notch signalling.[Delta1] (Mus musculus) PubMed

 31.

Ectopic circumferential expression of chordin and other dorsal genes is completely dependent on Nodal and fibroblast growth factor signaling, and is independent of a functional organizer. (Nodal) (Mus musculus) PubMed

 32.

The present study describes the isolation, sequencing and initial characterisation of an androgen receptor from zebrafish Danio rerio. (Mus musculus) PubMed

 33.

These results demonstrate that zfTRPM5 and PLC-beta2 colocalize in zebrafish taste receptor cells--zftrpm5 (Mus musculus) PubMed

 34.

Hsp90alpha1 plays an important role in muscle development, likely through facilitating myosin folding and assembly into organized myofibril filaments [Hsp90alpha1] (Mus musculus) PubMed

 35.

Axon terminals contain bicuculline-sensitive GABAA receptors and both picrotoxin-sensitive and insensitive GABAC receptors. Dendritic processes express zinc- and picrotoxin-sensitive GABAC receptors. (GABA C receptor) (Mus musculus) PubMed

 36.

The first X-ray crystal structures of zebrafish ribonucleases, RNases ZF-1a and-3e at 1.35-and 1.85 A resolution, respectively, is presented.[Rnase A] (Mus musculus) PubMed

 37.

The function and structure of the zebrafish (Danio rerio) Na+-sulfate cotransporter 1 (NaS1) cDNA and gene (slc13a1), was characterized.[NaS1] (Mus musculus) PubMed

 38.

Homozygous mno mutant embryos have a defect in the protoporphyrinogen oxidase gene. By 36 hours post-fertilization they are visibly anemic and porphyric. Human ppox partially rescues them. MNO. (Mus musculus) PubMed

 39.

Two putative cytosolic sulfotransferase sequences from zebrafish, designated SULT3 ST1 and ST2, were identified.[ST1, ST2] (Mus musculus) PubMed

 40.

Developmental expression analysis in zebrafish showed that K23 transcripts were maternally expressed in ovum and the amount of K23 transcripts increased gradually from zygote to pharyngula period [K23 protein] (Mus musculus) PubMed

 41.

SIN3 is required for multiple developmental events during the Drosophila life cycle[SIN3a] (Mus musculus) PubMed

 42.

Cdc2l1 is a previously unrecognized member of the Hh signal transduction cascade. (Mus musculus) PubMed

 43.

identification/characterization of a novel exocrine cell determinant gene, exdpf, highly expressed in the exocrine cell progenitors and differentiated cells of the developing pancreas in zebrafish [exocrine differentiation and proliferation factor, exdpf] (Mus musculus) PubMed

 44.

The data provide first evidence of the presence of Mel(1a) melatonin receptor in carp ovary and offer interesting perspectives especially for the study of the mechanisms of the control of its rhythmicity and its response to external factors. (Mus musculus) PubMed

 45.

mgo mutation genetically interacts with pax2a required for the initiation of mid-hindbrain boundary formation[mgo] (Mus musculus) PubMed

 46.

Activation of PKCgamma is necessary for the activity-dependent trafficking of AMPARs in embryonic zebrafish and is NMDA and SNARE-dependent and requires AMPARs to associate with both NSF and PICK1.[PICK1] (Mus musculus) PubMed

 47.

Results demonstrate that the vascular-specific marker angiomodulin (AGM) modulates vascular remodeling in part by temporizing the proangiogenic effects of VEGF-A. (Mus musculus) PubMed

 48.

Knockdown analysis using antisense morpholinos shows that reducing Axud1 levels impairs neural progenitor cell proliferation and survival, revealing an essential function of this gene for the growth of cephalic derivatives. (Axud1/Csrnp1) (Mus musculus) PubMed

 49.

LC8 facilitates nuclear import of Pak1 and this function is indispensable during vertebrate development [DYNLL1] (Mus musculus) PubMed

 50.

This study investigated the expression of genes encoding enzymes involved in long-chain polyunsaturated fatty acid biosynthesis, namely fatty acyl desaturase and Elovl5- and Elovl2-like elongases, during early embryonic development of zebrafish.[Fad] (Mus musculus) PubMed

 51.

Targeted knockdowns of all five genes of heme biosynthesis resulted in profound anemia without impacting erythroid lineage specification. (Mus musculus) PubMed

 52.

zebrafish lissencephaly 1 plays a very important role in embryonic development[lissencephaly 1a and lissencephaly 1b] (Mus musculus) PubMed

 53.

Data show that microtubules in neighboring cells reorient and target p115 RhoGEF to sites where dying cells are squeezed out of the epithelial sheet [p115 RhoGEF]. (Mus musculus) PubMed

 54.

Mg2+ regulates the cardiac mitoKATP channel from the matrix site by affecting both the channel conductance and gating. (Mus musculus) PubMed

 55.

FMSF showed high protein specificity and affinity for activating forward motility of goat cauda epididymal spermatozoa.[FMSF] (Mus musculus) PubMed

 56.

in endothelial cells CAMKII exerts a profound inhibition of endoplasmic reticulum Ca(2+) release, which is mediated by glycolytically generated ATP, possibly through ATP-dependent phosphorylation of the IP(3)R. (Mus musculus) PubMed

 57.

TOR deficiency results in developmental arrest at mid-to-late L3, which is accompanied by marked gonadal degeneration and a pronounced intestinal cell phenotype. TOR is a major upstream regulator of overall mRNA translation in C. elegans [TOR] (Mus musculus) PubMed

 58.

Crystals diffracted to 1.75 A and belong to the orthorhombic space group P2(1)2(1)2(1), with unit-cell parameters a = 44.3, b = 54.3, c = 60.2 A [ubiquitin-conjugation enzyme M7.1] (Mus musculus) PubMed

 59.

the genomic structure of PRKCD was analyzed; exon-intron genomic structure is highly conserved among mammals, while significantly diverged in C. elegans [PKC-delta] (Mus musculus) PubMed

 60.

AF9, called GLGPRPLRF-NH2 (AF9), is a ligand activating the cloned NPR-1 receptor [AF9] (Mus musculus) PubMed

 61.

expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1 is coordinated [two entries: Fre-1 and DCS-1] (Mus musculus) PubMed

 62.

Tudor-SN (tudor staphylococcal nuclease)--a protein containing five staphylococcal/micrococcal nuclease domains and a tudor domain--is a component of the RISC enzyme in Caenorhabditis elegans, Drosophila and mammals [Tudor-SN] (Mus musculus) PubMed

 63.

study of critical residues of choline kinase A2 [CKA-2] (Mus musculus) PubMed

 64.

Nuclear membrane protein that colocalizes with Ce-lamin and binds Ce-lamin but does not require Ce-lamin for its localization. (Matefin, mtf-1) (Mus musculus) PubMed

 65.

OSR-1 plays a central role in integrating stress detection and adaptation responses by invoking multiple signaling pathways to promote survival under hyperosmotic environments [OSR1] (Mus musculus) PubMed

 66.

Loss of function of this gene leads to the activation of a ced-3-dependent, ced-4-independent form of programmed cell death (pvl-5 gene) (Mus musculus) PubMed

 67.

cloning and the characterization of the third FMRFamide-related peptide (FaRP) receptor in Caenorhabditis elegans, the VRFa receptor 1 [VRfa receptor 1] (Mus musculus) PubMed

 68.

molecular cloning [CeENT1, CeENT2] (Mus musculus) PubMed

 69.

srf-3 is a mutant of Caenorhabditis elegans deficient in glycoconjugates (Mus musculus) PubMed

 70.

SPD-1 is a conserved microtubule-bundling protein that localizes to the spindle midzone and may play an early role in the pathway of midzone assembly. (Mus musculus) PubMed

 71.

hyperactivation of the Caenorhabditis elegans FGF receptor, EGL-15, similarly inhibits the differentiation of the hermaphrodite sex muscles (Mus musculus) PubMed

 72.

chondroitin polymerizing factor shows cell and organ-specific expression and has a critical role in chondroitin synthesis and embryonic cell division (Mus musculus) PubMed

 73.

results support the hypothesis that ncr-1 and ncr-2 are involved in intracellular cholesterol processing in C. elegans, and that a sterol-signaling defect is responsible for the Daf-c phenotype of the ncr-2; ncr-1 mutant [ncr1, ncr2] (Mus musculus) PubMed

 74.

AMP-activated protein kinase alpha subunit AAK-2 is activated by AMP and functions to extend lifespan. [AMPK alpha2 (AAK2)] (Mus musculus) PubMed

 75.

the first cloning, expression, and pharmacological characterization of members of a family of anion-selective acetylcholine receptor subunits(acetylcholine-gated chloride channel) (Mus musculus) PubMed

 76.

data indicate that binding sites in three PDI domains, a, b', and a', contribute to efficient C-P4H tetramer assembly [phy-1] (Mus musculus) PubMed

 77.

acts generally in gene expression (CYL-1, a cyclin); acts in heat-shock-inducible transcription (HSF-1 = heat-shock factor 1) (Mus musculus) PubMed

 78.

dac-1 is expressed in a subset of sensory neurons including the AFD thermosensory neurons and is regulated by the TTX-1 OTX homeodomain protein. [dac-1] (Mus musculus) PubMed

 79.

Both cof-2 mRNA and protein expression are developmentally regulated and both are affected by heat shock stress. (Mus musculus) PubMed

 80.

Required for the movement of homologous pairs of vulva cells towards this midline position. (Plx-1) (Mus musculus) PubMed

 81.

rde-3 is required for siRNA accumulation and for efficient RNAi in all tissues, and it is essential for fertility and viability at high temperatures. [rde-3] (Mus musculus) PubMed

 82.

This syudy cloned Caenorhabditis elegans lev-8 and demonstrated that it encodes a novel nicotinic acetylcholine receptor (nAChR) subunit, which has functional roles in body wall and uterine muscles as part of a levamisole-sensitive receptor. (Mus musculus) PubMed

 83.

CeBRC-2 regulates RAD-51 during homologous recombination and can also function independently of rad-51 in DSB repair processes (CeBRC-2 ). (Mus musculus) PubMed

 84.

three different MPS subunits combine with KVS-1 to form both binary (MPS-1.KVS-1) and ternary (MPS-2.MPS-3.KVS-1) complexes in chemosensory neurons [MPS-2, MPS-3] (Mus musculus) PubMed

 85.

aurora-B mediates phosphorylation of ZEN-4/MKLP1 in the completion of cytokinesis. [aurora B] (Mus musculus) PubMed

 86.

This paper demonstrates a concentration-dependent relationship of C. elegans CYP35A1, A2, A5, and C1 gene expression in response to four organic xenobiotics, namely atrazine, PCB52, fluoranthene, and lansoprazole. [CYP35] (Mus musculus) PubMed

 87.

Inhibition of PME-2 decreases embryonic survival rate of irradiated worms. (Mus musculus) PubMed

 88.

C. elegans daf-6 encodes a patched-related protein required for lumen formation. (Mus musculus) PubMed

 89.

The fos-1 is expressed in the anchor cell and controls invasion cell autonomously. (Mus musculus) PubMed

 90.

RIM disrupts ELKS active zone targeting, suggesting a tight association between the two proteins in vivo. (RIM) (Mus musculus) PubMed

 91.

The formation of the mitochondrial EF-Tu2/GTP/aminoacyl-tRNA ternary complex is probably supported by a unique interaction between the C-terminal extension of EF-Tu2 and the tRNA (EF-Tu2). (Mus musculus) PubMed

 92.

The assembly of fibulin-1C and fibulin-1D in multiple locations is dependent upon the presence of hemicentin.[HEMICENTIN] (Mus musculus) PubMed

 93.

Nup155 has an essential function in nuclear envelope formation in Caenorhabditis elegans embryos (Nup155). (Mus musculus) PubMed

 94.

Data that cyclin D and other regulators of the G1/S transition coordinate key regulators of axis formation and sex determination with cell cycle progression to achieve the sexually dimorphic somatic gonadal precursor cell asymmetric division [cyclin D]. (Mus musculus) PubMed

 95.

Caenorhabditis elegans Dcp8 is localized to distinct foci during embryogenesis. (Dcp8) (Mus musculus) PubMed

 96.

The polyamine synthesis enzyme spermidine synthase (SPDS) from the model nematode Caenorhabditis elegans has been cloned and characterized.(SPDS) (Mus musculus) PubMed

 97.

ACE-1 is an amphiphilic tetramer associated with a hydrophobic non-catalytic subunit, analogous to vertebrate T enzymes, whereas ACE-2 and ACE-3 are glycosylphosphatidylinositol-linked amphiphilic dimers[ACE-2] (Mus musculus) PubMed

 98.

The C. elegans SIR-2.1, a member of the Sir-2 family of NAD(+)-dependent protein deacetylases, has been shown to regulate nematode aging via the insulin/IGF pathway transcription factor daf-16. (Mus musculus) PubMed

 99.

In contrast to mitosis, both oocyte meiotic divisions proceeded normally following depletion of CENP-A, demonstrating the potential to uncouple assembly of outer-kinetochore proteins from CENP-A chromatin.[CENP-A] (Mus musculus) PubMed

 100.

The expression of nephrocystin-1 is DAF-19 dependent, that its expression is restricted to ciliated sensory neurons, and that both NPH-1 and NPH-4 concentrate at the transition zones at the base of the cilia, but are not found in the cilium axoneme. (Mus musculus) PubMed

 101.

Data suggest that inactive Ca2+/calmodulin-dependent protein kinase-II (CaMKII) forms tightly packed autoinhibited assemblies that convert upon activation into clusters of loosely tethered and independent kinase domains [CaMKII]. (Mus musculus) PubMed

 102.

May function in hypodermal cell migration during ventral enclosure by maintaining levels of WSP-1. (Waspip-1 = WASP-interacting protein isoform 1) (Mus musculus) PubMed

 103.

These results indicate that the actin-regulating activity of UNC-78 in cooperation with ADF/cofilin is essential for its in vivo function to regulate actin filament organization in muscle cells.(UNC-78) (Mus musculus) PubMed

 104.

Fatty acid synthase (FAS) gene, encoding for a key enzyme involved in the biogenesis of membrane lipids in rapidly proliferating cells, is a conserved target of the p53 family throughout the evolution.[fasn-1] (Mus musculus) PubMed

 105.

The cloning of daf-10 gene, this gene affects chemotaxis and are reqiured for intraflgellar transport. (Mus musculus) PubMed

 106.

PA28 is likely to function in collaboration with Hsp90.(PA28) (Mus musculus) PubMed

 107.

oxidative, osmotic, heat shock and starvation stresses induce germ cell apoptosis through a p53 and EGL-1 independent pathway [p53] (Mus musculus) PubMed

 108.

Data suggest that a NURF-like complex including ISW-1 promotes the expression of vulval cell fates by antagonizing the transcriptional and chromatin-remodeling activities of complexes similar to Myb-MuvB/dREAM, NuRD and Tip60/NuA4 [NURF1, ISW1] (Mus musculus) PubMed

 109.

These results suggest that AD-004 like protein (ADLP) is more likely a member of the adenylate kinase (AK6) family. (Mus musculus) PubMed

 110.

Shal channels play a role as the predominant transient outward current in Caenorhabditis elegans muscle [Shl-1 and Shk-1] (Mus musculus) PubMed

 111.

the critical residues essential for the unique serine specificity of C. elegans mitochondrial EF-Tu2 [EF-TU2] (Mus musculus) PubMed

 112.

Results suggest that prohibitin 2 is involved in a previously uncharacterized pathway of multidrug resistance [prohibitin 2] (Mus musculus) PubMed

 113.

The alternative-splicing defective-1(asd-1), encoding a new RNA-binding protein of the evolutionarily conserved Fox-1 family, as a regulator of the egl-15 reporter. (Mus musculus) PubMed

 114.

most prominent expression of the protein is observed in the intestine, while muscle and epithelial cells express asp-6 to a lesser extent[aspartyl protease 6] (Mus musculus) PubMed

 115.

analysis delineated a cohort of genes whose expression requires MPK-1 signaling in germ cells in the pachytene stage of meiosis I [MPK-1] (Mus musculus) PubMed

 116.

A possible mechanism for cyclin E-Cdk2-dependent differentiation: the establishment of cortical polarity by the centrosome.[Cyclin E,Cdk2] (Mus musculus) PubMed

 117.

C. elegans has at least two genes encoding functional d-aspartate oxidases (C47Ap and F18Ep) (Mus musculus) PubMed

 118.

Inositol monophosphatase is required in central interneurons of the mature nervous system for correct localization of synaptic components and thus for normal behavior. [Inositol monophosphatase] (Mus musculus) PubMed

 119.

expression of nex-2 & nex-4 was temporal, peaking at L1 stage followed by gradual decrease toward adult stage. NEX-2 & NEX-3 showed binding activities to phospholipids but not to phosphatidylcholine[nex-2, nex-3,nex-4] (Mus musculus) PubMed

 120.

cloning of poly(ADP-ribose) glycohydrolases (pme-4). (Mus musculus) PubMed

 121.

Caenorhabditis elegans expresses bona fide CRAC channels that require the function of Orai1- and STIM1-related proteins [orai1. STIM1, CRAC channel] (Mus musculus) PubMed

 122.

Lag-3 has a role in regulating p53-mediated germ cell apoptotic response to DNA damage and expression of Ced-13 and Egl-1, downstream pro-apoptotic targets of the C. elegans p53 homolog Cep-1 [Lag-3] (Mus musculus) PubMed

 123.

DYF-5 plays a role in the undocking of kinesin II from intraflagellar transport (IFT) particles and in the docking of OSM-3 onto IFT particles. (Mus musculus) PubMed

 124.

afp-6 that both the transcript and the peptides are expressed in a single cell in the ventral ganglion. (Mus musculus) PubMed

 125.

Characterize putative orthologs of human reduced folate carrier : folt-1 and folt-2 (Mus musculus) PubMed

 126.

the molecular identification and characterization of PNGase (png-1, F56G4.5) from Caenorhabditis elegans. This enzyme released both high mannose- and complex-type N-glycans from glycopeptides and denatured glycoproteins. (Mus musculus) PubMed

 127.

identified the sut-1 gene and found it encodes a novel protein. (Mus musculus) PubMed

 128.

Here, we present cellular and biochemical analysis of Letm1 of a C. elegans mutant that could serve as a model for Wolf-Hirschhorn syndrome (Mus musculus) PubMed

 129.

The fkb-6 gene is expressed in all stages of C elegans from embryo to adult with predominant expression being noted in the adult dorsal and ventral nerve cords. (Mus musculus) PubMed

 130.

Transgenic mice expressing C. elegans n-3 fatty acid desaturase (fat-1) gene produce milk with elevated levels n-3 polyunsaturated fatty acids, altering growth rates/visual development in suckling pups. (Mus musculus) PubMed

 131.

These results rule out the calmodulin/MLCK pathway as the missing regulator of cytokinesis in the C. elegans early embryo. [MLCK] (Mus musculus) PubMed

 132.

Cadmium-induced germline apoptosis is dependent on the MAPK signaling pathways. (Mus musculus) PubMed

 133.

Data show that the anti-obesity function of adipose (Adp) (worm Y73E7A.9, fly adp, and murine Wdtc1) is conserved from worms to mammals. [Adp] (Mus musculus) PubMed

 134.

UNC-80 encodes a novel, but highly conserved, neuronal protein required for the proper localization of the NCA-1 and NCA-2 ion channel subunits. (Mus musculus) PubMed

 135.

These results suggest that Galpha signaling and LET-99 control centration by regulating polarized actomyosin contraction.[GPA-16] (Mus musculus) PubMed

 136.

prom-1 regulates the timely progression through meiotic prophase I [prom-1] (Mus musculus) PubMed

 137.

ablation of BBS1 and BBS4 leads to alterations of s.c. sensory innervation and trafficking of the thermosensory channel TRPV1 and the mechanosensory channel STOML3[BBS1 and BBS4] (Mus musculus) PubMed

 138.

Olrn-1 and voltage-activated calcium channels are mediators and targets of AWC signaling that act at the transition between a multicellular signaling network and cell-autonomous execution of the decision. (OLRN-1 PROTEIN, C.ELEGANS) (Mus musculus) PubMed

 139.

Heat shock protein 16.2 reduce transfected abeta protein toxicittyby interacting directly with the Abeta peptide and altering its oligomerization pathways. [HSP16.2 protein] (Mus musculus) PubMed

 140.

These results suggest that C. elegans COM-1 plays a role in the generation of ssDNA tails that can load RAD-51, invade homologous DNA tracts and thereby initiate recombination. (Mus musculus) PubMed

 141.

RMD-1 functions in chromosome segregation in C. elegans embryos, possibly through the aurora B-mediated pathway. (Mus musculus) PubMed

 142.

siRNA-mediated knockdown of a splice variant of the PK-A catalytic subunit gene causes adult-onset paralysis in C. elegans (Mus musculus) PubMed

 143.

Long-chain polyunsaturated fatty acids are required for efficient synaptic vesicle recycling, probably by modulating synaptojanin localization at synapses.[Synaptojanin] (Mus musculus) PubMed

 144.

intracellular trafficking of MIG-14 by AP-2 and retromer plays an important role in Wnt secretion. [AP-2] (Mus musculus) PubMed

 145.

Regulation of the transport pathway between the Golgi apparatus and cell membrane may enable Wnt-producing cells to control the range of Wnt signaling in the tissue. [WNT] (Mus musculus) PubMed

 146.

DYF-11 is likely associated with IFT complex B. Domain analysis using DYF-11 deletion constructs revealed that the coiled-coil region is required for proper localization and ciliogenesis. [DYF-11] (Mus musculus) PubMed

 147.

analysis of 20 gene products that reproducibly enhanced misfolding of alpha-synuclein over the course of aging in human and C. elegans (Mus musculus) PubMed

 148.

PBO-4 is a putative Na+/H+ ion exchanger expressed on the basolateral membrane of intestine, juxtaposed to the posterior body muscles. In pbo-4 mutants the extracellular space is not acidified and the muscles fail to contract. (PB0-4 PROTEIN, C ELEGANS) (Mus musculus) PubMed

 149.

Polo kinases, via their polo box domains, bind to and regulate the activity of two key polarity proteins, MEX-5 and MEX-6.[DYRK2] (Mus musculus) PubMed

 150.

CIN-4 and TOP-2 are topoisomerase II isoforms that perform separate essential functions in centromere structure and function.[CIN-4] (Mus musculus) PubMed

 151.

meg-1 and meg-2 are expressed in the maternal germline and encode proteins that localize exclusively to P granules during embryonic germline segregation.[MEG-1, MEG-2] (Mus musculus) PubMed

 152.

DEPS-1 is a key component of the P-granule assembly pathway and its roles include promoting accumulation of several mRNAs. (Mus musculus) PubMed

 153.

CHE-12 and DYF-11 are conserved ciliary proteins that function cell-autonomously and are continuously required for maintenance of cilium morphology and function. [CHE-12 AND DYF-11] (Mus musculus) PubMed

 154.

In summary, our studies suggest that LNP-1 plays a role in synaptogenesis by regulating vesicular transport or localization.(LNP-1 PROTEIN, C.ELEGANS) (Mus musculus) PubMed

 155.

the extensive cys-loop LGIC gene superfamily observed for Caenorhabditis elegans namedlgc gene. (Mus musculus) PubMed

 156.

NMR solution structure of a model mimicking the interaction of let-7 miRNA with its complementary site in the 3' untranslated region of the lin-41 mRNA (let-7 miRNA). (Mus musculus) PubMed

 157.

Chromosome termini possess 3' G-strand overhangs and 5' C-strand overhangs; these two classes of overhangs are bound by two single-stranded DNA binding proteins, CeOB1 and CeOB2, which exhibit specificity for G-rich or C-rich telomeric DNA. [OB1,OB2] (Mus musculus) PubMed

 158.

The heat shock transcription factor, hsf-1, is required for enhanced thermotolerance, suppression of proteotoxicity, and lifespan extension by dietary restriction. (Mus musculus) PubMed

 159.

Data show that elipsa encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase, known to localize to cilia. (Mus musculus) PubMed

 160.

The C. elegans glycosyltransferase BUS-8 has two distinct and essential roles in epidermal morphogenesis. (Mus musculus) PubMed

 161.

The data suggest that MNP-1 is expressed in migrating muscle cells and localizes to the plasma membrane with the non-peptidase domain exposed to the extra-cellular environment.[MNP-1] (Mus musculus) PubMed

 162.

Membrane trafficking regulated by ipla-1 provides a mechanism to control the cortical asymmetry of beta-catenin.[PLA-1] (Mus musculus) PubMed

 163.

analysis of the expression pattern of the four mitochondrial adenine nucleotide transporter ant genes and their roles during the development of Caenorhabditis elegans [ANT-1.1, ant-1.2, ant-1.3, and ant-1.4] (Mus musculus) PubMed

 164.

CRA-1 as a key component in promoting the assembly of the tripartite synaptonemal complex structure. (Mus musculus) PubMed

 165.

Piwi acts upstream of an endogenous siRNA pathway in Tc3 silencing.[Piwi] (Mus musculus) PubMed

 166.

Arsenite induced germline apoptosis through a MAPK-Dependent, p53-independent pathway in Caenorhabditis elegans. (Mus musculus) PubMed

 167.

Expression of elt-5 and elt-6 increases during normal aging, and both of these GATA factors repress expression of elt-3, which shows a corresponding decrease in expression in old worms.[elt-5] (Mus musculus) PubMed

 168.

ZOO-1 cooperates with the cadherin-catenin complex to dynamically regulate strong junctional anchorage to the actin cytoskeleton during morphogenesis. (Mus musculus) PubMed

 169.

mRNA levels of several Dicer-regulated genes vary with changes in rncs-1 expression.[Dicer] (Mus musculus) PubMed

 170.

The results presented in this study demonstrates voltage dependent inactivation of the nematode ICln splice variant IClnN2.[IClnN2] (Mus musculus) PubMed

 171.

loss of UNC-64/DAT-1 interactions leads to enhanced synaptic dopamine release[syntaxin 1A or UNC-64 ] (Mus musculus) PubMed

 172.

GLO-3 as a novel player in the formation of lysosome-related organelles (Mus musculus) PubMed

 173.

GAP-3 is identified as the to date missing Caenorhabditiselegans member of the p120 RasGAP family.[GAP-3] (Mus musculus) PubMed

 174.

[STG-2] In STG-2 mutants, AMPAR-mediated currents and worm behaviors are selectively disrupted despite apparently normal surface expression and clustering of the receptors. (Mus musculus) PubMed

 175.

Sarcomeric actin organization is synergistically promoted by tropomodulin, ADF/cofilin, AIP1 and profilin in C. elegans(AIP1 and ADF/cofilin). (Mus musculus) PubMed

 176.

Endogenous Q9 (coq-9) content of coq-8(ok840) knockouts was demonstrated to be about 7% of that found in the wild-type, indicating the basal biosynthesis rate is reduced in this strain. (Mus musculus) PubMed

 177.

Purification, crystallization and X-ray structures of manganese superoxide dismutase2 and MnSOD3 from Caenorhabditis elegans (Mus musculus) PubMed

 178.

SZY-20 opposes the Plk4-related kinase ZYG-1 to limit centrosome size [SZY-20, Plk-4] (Mus musculus) PubMed

 179.

rep-1 functions only in the RAB-27 pathway. (Mus musculus) PubMed

 180.

Results suggest that pqbp-1.1 is involved in lipid metabolism of intestinal cells, and that dysfunction of lipid metabolism might underlie lean body, one of the most frequent symptoms associating with PQBP1-linked mental retrdation patients. (Mus musculus) PubMed

 181.

SEPA-1 functions as a bridging molecule in mediating the specific recognition and degradation of P granule components by autophagy during C. elegans embryogenesis. (Mus musculus) PubMed

 182.

mig-32 and spat-3 mutants are fertile, suggesting that Polycomb repression complex 1 (PRC1) function is not absolutely required in the germline for essential functions of PRC2 (Mus musculus) PubMed

 183.

rictor mutants are developmentally delayed, small in size, lay an attenuated brood, and are short-lived, indicating that Rictor plays a role in partitioning calories between long-term energy stores and vital organismal processes [Rictor] (Mus musculus) PubMed

 184.

findings indicate that SGK-1 is a mediator of Rictor activity; findings identify new physiological roles for TORC2, mediated by SGK, in regulation of C. elegans lipid accumulation and growth [Rictor] (Mus musculus) PubMed

 185.

mutations in alpha-1,2-mannosidase I may extend longevity by modulating dietary restriction [alpha-1,2-mannosidase I ] (Mus musculus) PubMed

 186.

A genetic screen identified DEX-1 and DYF-7, extracellular proteins required for dendritic tip anchoring, which act cooperatively at the time and place of anchoring.[DEX-1,DYF-7] (Mus musculus) PubMed

 187.

A reduction in teg-4 activity reduces the splicing efficiency of targets involved in controlling the balance between proliferation and differentiation.[Teg-4] (Mus musculus) PubMed

 188.

epg-1 encodes a divergent functional homolog of Atg13 in C. elegans.[Epg-1] (Mus musculus) PubMed

 189.

Data demonstrate that klf-3 is a hitherto unrecognized key regulator of fat metabolism in C. elegans, and is critical for maintaining normal fatty acid composition by regulating genes involved in a fatty acid desaturation pathway [Klf-3]. (Mus musculus) PubMed

 190.

NPF peptide from the nematode Caenorhabditis elegans was isolated and sequenced by tandem mass spectrometry[neuropeptide F] (Mus musculus) PubMed

 191.

analysis of heme binding and catalytic activity of Caenorhabditis elegans and human dual oxidase 1 [DUOX1] (Mus musculus) PubMed

 192.

in C. elegans, essential functions of Hop exist which apparently do not depend on the simultaneous binding of Hsp90 and Hsp70 to Hop.(Hop/Sti1) (Mus musculus) PubMed

 193.

Data show that TBX-35 and CEH-51 have overlapping function in MS blastomere lineage development. (Mus musculus) PubMed

 194.

GS28 and Ykt6 have a role in differentiation of stem cell-like epithelial cells (seam cells) and act redundantly for the proper expression of Golgi-resident proteins in C. elegans. [GS28, Ykt6] Results (Mus musculus) PubMed

 195.

an interactive relationship between let-7 miRNA function and ribosomal protein RPS-14 in regulation of terminal differentiation that may help in understanding the mechanism of translational control by miRNAs (Mus musculus) PubMed

 196.

Let-7 is the 1st known target of HBL-1 in C. elegans. A negative feedback loop mechanism controls let-7 and HBL-1 regulation. Let-7 (Mus musculus) PubMed

 197.

Notch and Prospero repress proliferation following cyclin E overexpression in bristle cell lineage. [Prospero] (Mus musculus) PubMed

 198.

pathways containing EGL-8-TPA-1-DKF-2 enable learning and behavioral plasticity by receiving, transmitting, and cooperatively integrating environmental signals targeted to both neurons and intestine [ DKF-2, DKF-2A, DKF-2B] (Mus musculus) PubMed

 199.

reducing expression of a dual oxidase, Ce-Duox1/BLI-3, causes a decrease in reactive oxygen species production by Caenorhabditis elegans in response to E. faecalis (Mus musculus) PubMed

 200.

LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans [let-7 microRNA] (Mus musculus) PubMed

 201.

Genetic and cell biological interactions suggest that CALF-1 couples intracellular traffic to functional maturation of CaV2 presynaptic calcium channels. (Mus musculus) PubMed

 202.

Knockdown of erasin, a platform for p97/VCP and ubiquilin binding, or knockdown of ubiquilin in human cells slowed degradation of two classical endoplasmic reticulum-associated protein degradation substrates.[erasin,Ubiquilin] (Mus musculus) PubMed

 203.

A complex feedback loop between DAF-12 and the let-7-family miRNAs involving both the repression of DAF-12 by let-7-family miRNAs and the ligand-modulated transcriptional activation and repression of let-7-Fam miRNAs by DAF-12, is reported.[let-7 miRNA] (Mus musculus) PubMed

 204.

NSF is not a required component of the cortical vesicle fusion machinery (Mus musculus) PubMed

 205.

Unichrom binds to genome DNA at G-stretch and degradation of Unichrom is required for segregation of chromosomes. (Mus musculus) PubMed

 206.

P16 is localized downstream of Alx1 in the PMC gene network, thereby linking the network to a specific "effector" protein involved in biomineralization (Mus musculus) PubMed

 207.

The presence of secretory pathway Ca2+-ATPases (SPCA) and Ca2+ store in sea urchin sperm, which refills by SPCA-type pumps, is shown. (Mus musculus) PubMed

 208.

a threefold increase in nucleolin leads to the complete absence of pre-rRNA maturation in addition to significant repression of RNA polymerase I transcription [ncl, =nucleolin] (Mus musculus) PubMed

 209.

both XCAP-E and pEg7 are localized in the granular component of the interphase nucleolus (XCAP-E and pEG7) (Mus musculus) PubMed

 210.

molecular cloning and biochemical characterization of two forms of Xenopus laevis UDP-GlcNAc: alpha6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II [GnT II-A, GNT II-B] (Mus musculus) PubMed

 211.

Kir4.1 and Kir5.1 potassium channels bind with a heteromeric interaction that influences rectification, gating, and pH sensitivity [Kir4.1] (Mus musculus) PubMed

 212.

These studies show that LKB1/XEEK1 is required for Wnt-beta-catenin signalling and provides novel insights into its role in vertebrate developmental patterning and carcinogenesis [LKB1(XEEK1)] (Mus musculus) PubMed

 213.

Data suggest that the effects of Xrx1 on proliferation, neurogenesis and gene expression are restricted to the rostral region of the embryo, implicating this gene as an anterior regulator of neurogenesis [Xrx1]. (Mus musculus) PubMed

 214.

xCIRP2 associates with specific mRNAs and can regulate the length of poly(A) tail in Xenopus oocytes [xCIRP2]; also xCIRP2 and ElrA may be involved in the regulation of mRNA stability at different steps [elavl1 or ElrA] (Mus musculus) PubMed

 215.

results show that XCTK2 microtubule cross-linking activity is regulated by the importin alpha/beta and Ran pathway through a classical bipartite nuclear localization signal [CTK2] (Mus musculus) PubMed

 216.

data demonstrate a positive role for protein phosphatase 2A:B56epsilon in the Wnt/beta-catenin signaling pathway [PP2A:B56epsilon] (Mus musculus) PubMed

 217.

Data support a mechanism in which maternal XSOX3 inhibits beta-catenin-mediated axis specification by repressing expression of Xnr5 [XSOX3]. (Mus musculus) PubMed

 218.

MECP2 along with methylated DNA and the SMRT complex has a role in cell fate decisions during primary neurogenesis in Xenopus [MeCP2] (Mus musculus) PubMed

 219.

Cdc48/p97-Ufd1-Npl4 is an essential chaperone that regulates transformation of the microtubule structure as cells reenter interphase [AAA-ATPase Cdc48/p97] (Mus musculus) PubMed

 220.

p42 MAPK and Cdc2 system normally generates an irreversible biochemical response from a transient stimulus, but the response becomes transient when positive feedback is blocked [cdc2, p42 MAPK] (Mus musculus) PubMed

 221.

Hoxb4 directly induces the expression of FLASH, a component of the FAS-CAPSASE8 apoptotic pathway, in the notochord of embryos after neurulation. [Hoxb4][FLASH] (Mus musculus) PubMed

 222.

the autoactivation mechanism of Aurora A [Aurora A] (Mus musculus) PubMed

 223.

histone variant H2AZ stabilizes the histone octamer within the nucleosome [histone h2AZ] (Mus musculus) PubMed

 224.

plays an essential role in the control of cell movement during gastrulation [platelet-derived growth factor receptor] (Mus musculus) PubMed

 225.

Sox17 and beta-catenin interact to transcribe endodermal target genes [Sox17] (Mus musculus) PubMed

 226.

CaMKIx plays some critical role in the late stages of embryogenesis of Xenopus laevis [CaMKIx] (Mus musculus) PubMed

 227.

PTK7 is required for neural convergent extension and neural tube closure [ptk7] (Mus musculus) PubMed

 228.

paraxial protocadherin can interact with the Xenopus Frizzled 7 receptor, and both proteins contribute to the development of separation [paraxial protocadherin] (Mus musculus) PubMed

 229.

activity of both, Xenopus paraxial protocadherin and planar cell polarity signalling, is required to coordinate convergence and extension movements [paraxial protocadherin] (Mus musculus) PubMed

 230.

Glut1 glucose transporter transmembrane segment 3 is an outer helix [Glut1] (Mus musculus) PubMed

 231.

Kif2a is targeted to spindle poles by dynein/dynactin [Kif2a] (Mus musculus) PubMed

 232.

Data show that two members of Par proteins, 14-3-3 (Par-5) and atypical PKC (PKClambda), regulate the serine/threonine kinase Par-1 to control Xenopus gastrulation [Par-1] (Mus musculus) PubMed

 233.

Each of the SNAP-25 isoforms in the Xenopus pituitary and brain has a distinct function in cellular fusion processes including secretion, depending on the type of secreted hormone and/or the activity state of the cell.(snap-25a protein, Xenopus) (Mus musculus) PubMed

 234.

Data suggest that Xenopus oocytes have a limited capacity to guide the assembly of nicotinic acetylcholine receptor alpha7 subunits, but not 5-hydroxytryptamine 3A subunits to homopentamers [nicotinic acetylcholine receptor alpha7]. (Mus musculus) PubMed

 235.

A dominant-negative mutant of xAC7 induced hormone-independent oocyte maturation and accelerated progesterone-induced oocyte maturation; findings suggest xAC7 is a major component of the G2 arrest mechanism in Xenopus oocytes. [adenylyl cyclase 7 (AC7)] (Mus musculus) PubMed

 236.

Novel conditional and hypomorphic alleles of smad2 were generated. (Mus musculus) PubMed

 237.

ZPA has a role in egg envelope hardening after proteolysis [egg envelope component ZPA] (Mus musculus) PubMed

 238.

Oocytes expressing Cx26 exhibited large membrane conductances over a broad range of hyperpolarizing and depolarizing membrane potentials (connexin 26). (Mus musculus) PubMed

 239.

At late tail bud stages flotillin1B expression is more restricted in the dorsal neural tube and head sensory structures. (flotillin 1B) (Mus musculus) PubMed

 240.

Myo3A plays a role in the morphogenesis and maintenance of calycal processes of vertebrate photoreceptors [myo3a] (Mus musculus) PubMed

 241.

May be an important factor for skin maturation, may also serve as a good marker for epidermis maturation. (Nkx-2.3) (Mus musculus) PubMed

 242.

EDEN-BP-dependent post-transcriptional regulation of gene expression is required for the process of somitic segmentation.(EDEN-BP) (Mus musculus) PubMed

 243.

interaction of tau with microtubules may modify local mechanical properties of individual microtubules and play a crucial role in the remodeling of the microtubules cytoskeleton during neuronal plasticity [tau] (Mus musculus) PubMed

 244.

Purification, crystallization and preliminary X-ray analysis of the N-terminal domain of NO38 [NO38, also called nucleophosmin or B23] (Mus musculus) PubMed

 245.

[NRP-1; BruL-1 or Etr-1] Nrp-1 is expressed in both stem cells and mitotic precursors in developing Xenopus retina. BruL-1 is a good marker of post-mitotic retinal neurons. (Mus musculus) PubMed

 246.

activin a has a role in development of tooth and eye in Xenopus [Activin A] (Mus musculus) PubMed

 247.

analysis of activin-like kinase receptor-4 (ALK4) developmental expression in Xenopus laevis [ALK4] (Mus musculus) PubMed

 248.

Xenopus laevis CYP17 regulates androgen biosynthesis independent of the cofactor cytochrome b5 [CYP17, cytochrome b5] (Mus musculus) PubMed

 249.

Regulator of the Wnt signaling pathway. (PR72) (Mus musculus) PubMed

 250.

Results suggest that one functional subunit can regulate the pH-dependent gating of the Kir1.1 channel, and that channel sensitivity to pH increases with additional subunits. (Mus musculus) PubMed

 251.

ionotropic glutamate receptor 3 has specific N-terminal domain regions that form the subunit oligomerization interfaces that control subtype-specific receptor assembly [GLUR3] (Mus musculus) PubMed

 252.

rapid movements of TFIIIA side chains permit them to make fluctuating contacts with adjacent bp in the DNA of the gene (5S rRNA) (Mus musculus) PubMed

 253.

may mediate neurogenesis control by maintaining splicing and translational silencing in undifferentiated neural cells (SRp38) (Mus musculus) PubMed

 254.

Data show that the anaphase-promoting complex (APC/C)-Cdc20 can mediate cyclin B degradation in cytostatic factor-arrested Xenopus eggs and extracts [Cdc20, cyclin B]. (Mus musculus) PubMed

 255.

Wnt-4 is required for eye development in Xenopus laevis. (Mus musculus) PubMed

 256.

The spinophilin (SPL), which binds the third intracellular loop (3iL) of several GPCRs, binds the N-terminal domain of RGS2. (Mus musculus) PubMed

 257.

a novel function of xPontin and xReptin as co-repressors in the c-Myc/Miz-1 pathway [Miz-1] (Mus musculus) PubMed

 258.

solution structure of Quaking protein [Quaking protein ] (Mus musculus) PubMed

 259.

directly involved in ribosome biogenesis (NO52) (Mus musculus) PubMed

 260.

MNAR participates in G protein-regulated meiosis in Xenopus laevis oocytes [MNAR, also called PELP1] (Mus musculus) PubMed

 261.

Xenopus beta2-microglobulin mRNA is expressed ubiquitously with highest expression in intestine, spleen, and thymus, correlating well with classical class Ia expression [beta2-microglobulin] (Mus musculus) PubMed

 262.

Eg5 can tether microtubule plus-ends, suggesting an additional microtubule-binding mode for Eg5 [Eg5] (Mus musculus) PubMed

 263.

Gonadal proopiomelanocortin convertase gene expression is demonstrated in Xenopus laevis. (prohormone convertase 1, prohormone convertase 2) (Mus musculus) PubMed

 264.

The CaBP1-binding sites at the C terminus of TRPC5 are closely localized, but not identical, to CaM-binding sites. We conclude that TRPC5 is a Ca2+-regulated channel, and its activity is negatively controlled by CaBP1.[TRPC5] (Mus musculus) PubMed

 265.

molecular cloning of connexin40.4; during Xenopus laevis development, connexin40.4 was first expressed after the mid-blastula transition [connexin40.4] (Mus musculus) PubMed

 266.

investigated the role of steroid receptor coactivator 3 (SRC3) in gene activation by thyroid hormone receptor (TR) in vivo during development(steroid receptor coactivator-3) (Mus musculus) PubMed

 267.

PDGFRalpha-mediated cell survival requires PLCgamma and phosphatidylinositol 3-kinase signaling, and that PDGFRalpha with binding sites for these two signaling factors is sufficient for this activity (Mus musculus) PubMed

 268.

Xenopus NKCC is stimulated by insulin and genistein in a synergistic manner (Mus musculus) PubMed

 269.

isolation of Xmad1, Xmad3 and Xmnt, novel genes belonging to the Mad family and description of their temporal and spatial expression patterns during embryogenesis [mad3, mnt mad1] (Mus musculus) PubMed

 270.

A novel Daple-like protein, a positive regulator of the Wnt/beta-catenin pathway, named as xDal (Xenopus Daple-like)was identified.(xDal) (Mus musculus) PubMed

 271.

Data show that Esr1 and Esr10 are differentially regulated both in terms of Notch input and its interaction with heterologous factors [Esr1]. (Mus musculus) PubMed

 272.

TFAP2alpha is important for ectoderm development and is required for the molecular linkage between the epidermis and neural crest in the Xenopus embryo. (Mus musculus) PubMed

 273.

Down-regulation of TCOF1 (treacle) expression in X. laevis oocytes resulted in inhibition of rDNA gene transcription and suggests evolutionary conservation of the function of treacle in ribosomal RNA biogenesis in higher eukaryotes [TCOF1] (Mus musculus) PubMed

 274.

calcium-activated CaMKII triggers exit from meiosis II by sensitizing the APC/C inhibitor XErp1 for polo-like kinase 1 (Plx1)-dependent degradation [XErp1] (Mus musculus) PubMed

 275.

Agrin regulates neurite extension and provide evidence for an unanticipated role of agrin in growth-cone steering in developing neurons. [ARGIN] (Mus musculus) PubMed

 276.

Furthermore, while activities to process procaspase-8 and procaspase-9 appeared in SAMDC-overexpressed apoptotic embryos, the activity to process procaspase-8 did not appear in p53-overexpressed apoptotic embryos. (Mus musculus) PubMed

 277.

These results suggest that pEg3 might play a role at the cell cortex during mitosis.[Protein kinase pEg3] (Mus musculus) PubMed

 278.

complex containing Smicl and the newly induced Xlim1 induces expression of Chordin [Smicl] (Mus musculus) PubMed

 279.

SOX7 and SOX18b are essential regulators of cardiogenesis in Xenopus. [Sox18beta] (Mus musculus) PubMed

 280.

Blocking mitotic entry by adding the catalytic subunit of protein kinase A results in increased wee1 Ser549 phosphorylation and maintenance of cdc25C. (protein kinase A) (Mus musculus) PubMed

 281.

Nrarp independently regulates canonical Wnt and Notch signalling by modulating LEF1 and Notch protein turnover, respectively.[Nrarp (Notch-regulated ankyrin repeat protein)] (Mus musculus) PubMed

 282.

The Werner syndrome protein is a RecQ-type DNA helicase, which seems to participate in DNA replication, double-strand break (DSB) repair, and telomere maintenance. (Mus musculus) PubMed

 283.

identified 71 transcripts that are upregulated by Mixer or Sox17beta[Mixer and Sox17beta (Mus musculus) PubMed

 284.

Noelin-4 protein is glycosylated and secreted and that it interacts with Noelin-1, an isoform previously found to promote differentiation in neuralized animal caps [Noelin-4]. (Mus musculus) PubMed

 285.

Lox-related enzymes are required for the proper formation of the ECM during X. laevis development.[Xlox-1] [Xlox-3] (Mus musculus) PubMed

 286.

[Neuroserpin] Xenopus neuroserpin may play an important physiological role, e.g. as a serine protease inhibitor during development, and for proper neuronal and neuroendocrine cell functioning. (Mus musculus) PubMed

 287.

The alpha-neurexins are differentially regulated during development with respect to gene temporal and spatial expression and alternative splicing. [nrxnI alpha, nrxnII alpha, nrxnIII alpha] (Mus musculus) PubMed

 288.

MRN complex is not required for efficient and accurate NHEJ-mediated repair of DSBs in this vertebrate system (Mre11). (Mus musculus) PubMed

 289.

We cloned the full-length gene encoding Xenopus separase from an oocyte cDNA library. Purified xSeparase can cleave the human alpha-kleisin subunit of cohesin in vitro but cannot bind to hSecurin when these two proteins are coexpressed in 293T cells. (Mus musculus) PubMed

 290.

[calretinin]Most calcium-binding proteins calretinin-containing spinal cord neurons were located in the superficial dorsal gray field, but with distinct topography. (Mus musculus) PubMed

 291.

The role of Xorbit in spindle assembly and function is studied. (Mus musculus) PubMed

 292.

These results demonstrate for the first time a PKA-restrictive and a PKA-permissive phase in oocyte maturation [Protein kinase A] (Mus musculus) PubMed

 293.

X-Delta-2 is involved in the migration of the cranial placodes cells, as well the migration of the cranial neural crest cells during neurogenesis.(X-Delta-2) (Mus musculus) PubMed

 294.

These results demonstrate that a reversible Pum2 interaction controls RINGO/Spy mRNA translation and, as a result, CPEB-mediated cytoplasmic polyadenylation. (Mus musculus) PubMed

 295.

embryonic expression pattern of the SLC20A1; SLC20A1 mRNA is expressed in the somitic mesoderm and lower level of expression is detected in the neural tube, eye, and neural crest cells [SLC20A1] (Mus musculus) PubMed

 296.

Dissociated by RanGTP, NuSAP may aid to maintain spindle integrity by stabilizing and cross-linking microtubules around chromatin. RANFRP AND NuSAP) (Mus musculus) PubMed

 297.

XlHMGA2alpha appears to be preferentially expressed during oogenesis and after midblastula transition, whereas XlHMGA2beta expression predominates after neurulation, suggesting an individual transcriptional regulation. (Mus musculus) PubMed

 298.

Bowline is a novel protein interacting with Groucho/TLE and may play a role in somitogenesis (bowline protein) (Mus musculus) PubMed

 299.

xSyn4 and fibronectin cooperate with xFz7 and Wnt in the specific activation of the non-canonical Wnt pathway.[Syndecan-4] (Mus musculus) PubMed

 300.

MELK phosphorylation by MPF and MAPK enhance its activity during M-phase [MELK, MPF, MAPK] (Mus musculus) PubMed

 301.

These results show that somitogenesis and patterning of the anteroposterior axis are closely linked involving Hox genes and X-Delta-2, suggesting the existence of a coordination mechanism between somite formation and axis patterning. [X-Delta-2] (Mus musculus) PubMed

 302.

PCNS (Protocadherin in Neural crest and Somites), a novel Pcdh in Xenopus, is initially expressed in the mesoderm during gastrulation, followed by expression in the cranial neural crest and somites. [PCNS] (Mus musculus) PubMed

 303.

results confirm that the level of expression of both TOPK and DYRK1A is significantly higher in oocytes induced to mature in insulin than in oocytes that are induced to mature by injection of Val 12-ras-p21 [TOPK] (Mus musculus) PubMed

 304.

Required for normal vascular development in the frog embryo and has properties consistent with a role during normal and pathological angiogenesis. (apelin or Apln) (Mus musculus) PubMed

 305.

results support a recent proposal that AKAP participates in regulating protein kinase A activity independently from cAMP [A kinase anchoring protein, AKAP, portein kinase A type II] (Mus musculus) PubMed

 306.

These data suggest that pEg6 acts as a vegetally localized factor contributing to the actin nucleation process during Xenopus early development.(EG6 PROTEIN, XENOPUS) (Mus musculus) PubMed

 307.

metastasis-associated kinase is a novel regulator of Wnt signaling during morphogenetic movements, and eye and brain development in Xenopus embryos. (metastasis-associated kinase--MAK) (Mus musculus) PubMed

 308.

Nup107-160 complex is dynamic in mitosis and that it promotes spindle assembly in a manner that is distinct from its functions at interphase nuclear pores.[Nup107, Nup160] (Mus musculus) PubMed

 309.

We show here that EDEN-BP is able to oligomerize. A 27-amino-acid region of EDEN-BP was identified as a key domain for oligomerization.Impairing oligomerization specifically abolished EDEN-dependent deadenylation.[EDEN-BP (EDEN-binding protein)] (Mus musculus) PubMed

 310.

results provide the first evidence that Neogenin acts as an axon guidance molecule in vivo and support a model whereby Neogenin-expressing axons respond to a combination of attractive and repulsive cues as they navigate their ventral trajectory [Neogenin] (Mus musculus) PubMed

 311.

Xenopus laevis POU91 protein, an Oct3/4 homologue, regulates competence transitions from mesoderm to neural cell fates (Mus musculus) PubMed

 312.

We identify Partner of paired (Ppa) as the F-box component of a modular E3 ligase, and show that it is expressed in neural crest-forming regions, and that it binds to and promotes ubiquitin-mediated proteasomal degradation of Slug (Mus musculus) PubMed

 313.

although Smad4alpha and Smad4beta may have similar activities, they are differentially utilized during frog embryogenesis, with only Smad4beta being essential for mesoderm induction [Smad4alpha, Smad4beta] (Mus musculus) PubMed

 314.

Proper expression of XTsh1 is essential for segmentally restricted gene expression in the posterior brain and CNC and suggest for the first time that teashirt genes act as positional factors also in vertebrate development.[XTsh1] (Mus musculus) PubMed

 315.

Grhl3 promotes superficial gene expression in the deep layer of the epidermis. (Grhl3,grainyhead-like 3) (Mus musculus) PubMed

 316.

Cyclin B dissociation from CDK1 precedes cyclins B degradation upon CDK1 inactivation in mitotic embryo extracts and that proteasome proteolytic activity is dispensable for both activation and inactivation of CDK1 in such extracts. [Cyclin B2, MPF,] (Mus musculus) PubMed

 317.

Results indicate PN-1 could have a natriuretic role by inhibiting prostasin activity. Aldosterone and TGF-beta reciprocally regulate expression of PN-1. PN-1 could represent a factor that contributes to regulation of ENaC activity [prostasin and PN-1]. (Mus musculus) PubMed

 318.

ET receptors in pigment cells of vertebrate species were identified by RT-PCR assays, and the differential expression of the various subtypes in each species was compared by quantitative PCR.(Endothelin receptor Ax, Endothelin receptor C] (Mus musculus) PubMed

 319.

Emi2 plays an essential role in meiotic but not mitotic cell cycles [emi2] (Mus musculus) PubMed

 320.

Several CKI isoforms including CKIalpha and Gish/CKIgamma can phosphorylate the Wg coreceptor Arrow (Arr), which may account, at least in part, for their positive roles in the Wg pathway. (Mus musculus) PubMed

 321.

A novel member of the hairy/Enhancer of split [E(spl)] gene family in Xenopus, XHes2, as a regulator to bias retinal precursor cells towards a glial fate, was identified. (Mus musculus) PubMed

 322.

identify inositol 1,4,5 trisphosphate receptor type 1 (IP3R1) phosphorylation by M-phase kinases as a regulatory mechanism of IP3R1 function in eggs that serves to optimize internal calcium release at fertilization [IP3R1]. (Mus musculus) PubMed

 323.

Whole-mount in situ hybridization analysis showed that rhoB is expressed in the dorsal marginal zone early in gastrula then in the dorsal midline and at mid-neurula stages, rhoB expression extends to the CNS, presomitic mesoderm and somites.[RhoB protein] (Mus musculus) PubMed

 324.

high level of sustained maternal Jun NH2-terminal kinase activity in early Xenopus embryos may provide a timing mechanism for controlling the dorsal axis formation[Jun NH2-terminal kinase ] (Mus musculus) PubMed

 325.

report the identification and developmental expression of Xenopus laevis hmga2beta (Xlhmga2beta) (Mus musculus) PubMed

 326.

B56epsilon regulatory subunit of protein phosphatase 2A (PP2A) is involved in Xenopus eye induction and subsequent eye field separation. [PP2A:B56epsilon] (Mus musculus) PubMed

 327.

Enhanced expression of SCP2 in Xenopus embryos leads to an extensive loss of linker phosphorylation of Smad1 and Smad2. (Mus musculus) PubMed

 328.

Maskin phosphorylation-dephosphorylation also oscillates with the cell cycle and is controlled by the kinase CDK1 and the phosphatase calcineurin [CDK1] (Mus musculus) PubMed

 329.

These observations identify PP2A/B56delta as a central checkpoint effector and suggest a mechanism for controlling 14-3-3 interactions to promote mitosis. (Mus musculus) PubMed

 330.

By the cotransport mechanism about 35 water molecules were transported for each sugar molecule by a mechanism within the GLUT2 [GLUT2]. (Mus musculus) PubMed

 331.

These results suggest that XSu(H)2 is involved in mesoderm formation and the cell movement of gastrula embryos in a different manner from the Notch signaling target gene, XESR-1-mediated Notch signaling pathway. [XSu(H)2 protein] (Mus musculus) PubMed

 332.

These results suggest that XSu(H)2 is engaged in the cell fate decision during gastrulation through the gene expression of the Xoct25/91-mediated pathway.[Suppressor of hairless 2] (Mus musculus) PubMed

 333.

These findings demonstrate that the spatial localization of type II PKA to growth cone filopodia plays an important role in the regulation of growth cone motility and guidance by cAMP.[type II protein kinase A] (Mus musculus) PubMed

 334.

The data suggest that EphA4 activation sequesters active Cdc42 and in this way down-regulates cell-cell adhesion.[Pak1, Cdc42] (Mus musculus) PubMed

 335.

Rx1 and Pax6 differentially modify the ability of eye field precursors to produce different neurotransmitter subtypes of amacrine cells. (RX1, Pax6) (Mus musculus) PubMed

 336.

Galphai3-induced activation of G protein-activated K+ channels by Gbetagamma, demonstrated in intact cells, supports the hypothesis that Galphai regulates ion gating under physiological conditions [Galphai3 and G protein beta/gamma]. (Mus musculus) PubMed

 337.

Study isolated 35-kDa Ca-dependent lectin, XCL-1 from adult serum and a cDNA for an XCL-1-related protein, XCL-2; XCL-2gene expression was significantly increased in the regenerating tails, suggesting its role in tail regeneration.[XCL-1, XCL-2 protein] (Mus musculus) PubMed

 338.

over-expression of PHD47 rescued the small eye abnormality caused by xSiah2 [HIF-prolyl 4-hydroxylase] (Mus musculus) PubMed

 339.

Full-length Eg5 moves processively and stepwise along microtubule bundles. Eg5 typically detached from microtubules before stalling. This behavior may reflect a regulatory mechanism important for the role of Eg5 in the mitotic spindle. (Mus musculus) PubMed

 340.

Xenopus Gef (XGef), a Rho-family guanine-exchange factor, influences the activating phosphorylation of CPEB. (Xgef) (Mus musculus) PubMed

 341.

the identification and functional characterization of Xenopus Tetraspanin-1 (xTspan-1). (Mus musculus) PubMed

 342.

The ontogenetic patterns of Aro, Srd5a1 and Srd5a2 suggest that these genes are involved in sexual differentiation of gonads and brain already in early developmental stages.[srd5a1 and srd5a2] (Mus musculus) PubMed

 343.

Overexpression of Nrl dramatically increased the number of lens fibers, both directed photoreceptor precursors to become rods at the expense of cones. (Nrl = leucine zipper transcription factor) (Nr2e3 = nuclear receptor subfamily 2, group E, member 3) (Mus musculus) PubMed

 344.

In Xenopus oocytes, p42 MAPK interacts with hypophosphorylated Cdc25 before meiotic induction. During meiotic induction, p42 MAPK phosphorylates Cdc25 at three sites, increasing Cdc25's phosphatase activity. [p42 MAPK] (Mus musculus) PubMed

 345.

results clarify the direct link of the classical Mos-MAPK pathway to Erp1 in meiotic arrest of vertebrate oocytes [Erp1] (Mus musculus) PubMed

 346.

xEIAP/XLX is physiologically phosphorylated by p42MAPK in Xenopus unfertilized eggs[p42MAPK and xEIAP] (Mus musculus) PubMed

 347.

Vg1 and VegT can repress the ability of dorsal-animal retinogenic blastomeres to form retina, converting the lineage from neural/retinal to non-neural ectodermal and endo-mesodermal fates. [VegT] (Mus musculus) PubMed

 348.

Casein kinase I and FGF signalling converge on an antagonistic regulation of FoxG1, which in turn controls neurogenesis in the forebrain. (Mus musculus) PubMed

 349.

Report demonstrates that the neuroectoderm/mesoderm boundary is controlled by the chromatin remodeling ATPase CHD4/Mi-2beta. [CHD4 protein] (Mus musculus) PubMed

 350.

This investigation reveals important role of xVAP019 in embryonic development.(xVAP019) (Mus musculus) PubMed

 351.

Data show that ATM (ataxia-telangiectasia mutated) regulates Xenopus TopBP1 by phosphorylating serine 1131 and thereby strongly enhancing association of TopBP1 with ATR(ATM and Rad3-related) [TopBP1]. (Mus musculus) PubMed

 352.

stimulation of ENaCs by EPA occurs via SGK in membrane-bound compartments containing an AKAP, activated PKA, and a phosphodiesterase [AKAP] (Mus musculus) PubMed

 353.

findings implicate xGLUT1 as an important player during gastrulation cell movement in Xenopus [GLUT1] (Mus musculus) PubMed

 354.

Analysis of kinetics and substrate specificity of SLC20A1. (Mus musculus) PubMed

 355.

Lysine-specific demethylase gene was cloned and its expression in metamorphosis examined; study concluded that LSD1 participates in the regulation of metamorphosis by thyroid hormone- transcriptional factor-induced chromatin remodeling. [LSD1 protein] (Mus musculus) PubMed

 356.

homomeric and heteromeric Kir2.x channels are activated by beta(3)-adrenoceptors via different protein kinase-dependent pathways: Kir2.1 subunits are modulated by PKC, whereas Kir2.2 is modulated by protein kinase A. [Kir2.2][adrenergic beta3 receptor] (Mus musculus) PubMed

 357.

findings show that neither cyclin B2 degradation nor Thr-161 dephosphorylation participates directly in CDK1 inactivation as measured by histone H1 kinase decline upon the exit from mitotic M-phase in Xenopus embryo extract[CDK1] (Mus musculus) PubMed

 358.

TOPK is required for oocyte maturation induced by wild-type p21. [TOPK] (Mus musculus) PubMed

 359.

these results suggest that the Kir4.1-Kir5.1 but not the homomeric Kir4.1 channel is strongly inhibited by PKC activation.[Kir4.1] (Mus musculus) PubMed

 360.

These studies support a model in which vertebrate Ctr1 functions as a key regulator of the differentiation capacity of both stem and progenitor cell populations.[Ctr1] (Mus musculus) PubMed

 361.

The cloning, expression, purification, and antibody production of a PNAS-4 homolog (named xPNAS-4) from Xenopus laevis were reported.(xPNAS-4) (Mus musculus) PubMed

 362.

Ceramide mediates TNF-alpha inhibition of the renal epithelial sodium channel (ENaC) via a pathway associated with PKC-dependent externalization of phosphatidylserine [ENaCand protein kinase C]. (Mus musculus) PubMed

 363.

interaction of the 9-1-1 complex (Rad9-Hus1-Rad1) with the BRCT I-II region of TopBP1 is necessary for binding of ATR-ATRIP to the ATR-activating domain of TopBP1 and the ensuing activation of ATR [TOPBP1] (Mus musculus) PubMed

 364.

Cloning and expression studies of the DRR1 gene during embryo development (DRR1). (Mus musculus) PubMed

 365.

Cleavage of Geminin by caspase-3 is not relevant to its function as regulator of DNA synthesis, suggesting that its cleavage may be relevant to its role in differentiation.[Caspase-3] (Mus musculus) PubMed

 366.

Custom-tailored current of Kv2.1/Kv8.2 functionally contributes to photoreception, which why mutations of Kv8.2 lead to a genetic visual disorder. [KV8.2] (Mus musculus) PubMed

 367.

Rho GTPases can regulate the expression of XSnail2 during neural crest ontogeny (Mus musculus) PubMed

 368.

These data suggest a model in which ERK phosphorylation must be spatially coupled to integrin-mediated DIM-7 activation to make a complex that can be imported efficiently.[Dim-7] (Mus musculus) PubMed

 369.

Xenopus laevis microRNAs miR-15 and miR-16 restrict the size of the organizer by targeting the Nodal type II receptor Acvr2a [Acvr2a & Nodal & miRNAs too?] (Mus musculus) PubMed

 370.

Cep57/Translokin is required for stable microtubule attachments at the kinetochore and at the centrosome. (Mus musculus) PubMed

 371.

A phosphorylated protein with molecular mass of 25,000 (pp25) derived from Xenopus laevis vitellogenin B1 may play different role from those of yolk proteins lipovitellin and phosvitin in X. laevis oocytes and developing embryos. (Mus musculus) PubMed

 372.

Here we identify Xenopus laevis Tipin as a substrate for cyclin E/cyclin-dependent kinases 2 that is phosphorylated in interphase and undergoes further phosphorylation upon entry into mitosis. (Mus musculus) PubMed

 373.

Sos (Son of Sevenless Proteins) forms part of a multiprotein complex vital for intracellular signaling via LV1 (lipovitellin 1) in xenopus ooxytes. (Mus musculus) PubMed

 374.

a mutation in the Sall1 repression motif disrupts recruitment of the nucleosome remodeling and deacetylase complex and repression of Gbx2 (Mus musculus) PubMed

 375.

Immunohistochemical techniques were employed to investigate orexin-A-like and orexin receptor 1 (OX1R)-like immunoreactivities in the Xenopus pituitary gland.[Orexin A, orexin receptor 1] (Mus musculus) PubMed

 376.

Ubp-M regulates Hox gene expression through H2A deubiquitination and that blocking the function of Ubp-M results in defective posterior development in Xenopus laevis [Ubp-M] (Mus musculus) PubMed

 377.

Characterization of the PL-I-related SP2 protein from Xenopus.[Sp2] (Mus musculus) PubMed

 378.

SHP-2 functions within the FGF/MAPK pathway to maintain survival of proliferating populations of cardiac progenitor cells.[SHP-2, also known as PTPN11] (Mus musculus) PubMed

 379.

prospective neural cells are poised to respond to Smad2 and Smad1 signals to adopt mesodermal and non-neural ectodermal fates even at gastrula stages[ Smad1 and Smad2] (Mus musculus) PubMed

 380.

Bod1 is a novel kinetochore protein that is required for the detection or resolution of syntelic attachments in mitotic spindles.[Bod1] (Mus musculus) PubMed

 381.

CPEB, partnered with several highly conserved RNA-binding partners, inhibits protein synthesis in oocytes using a novel pairing of 4E-T and eIF4E1b [4E-T] (Mus musculus) PubMed

 382.

Xhes6 is essential for XmyoD induction and acts by relieving Groucho-mediated repression of gene expression.[Hes6, MyoD] (Mus musculus) PubMed

 383.

Intracellular Ca(2+) plays a role as the second messenger in hypotonic stress-induced Na(+) transport by stimulating transcription of SGK1 and ENaC subunits [SGK1 and ENaC]. (Mus musculus) PubMed

 384.

These results suggest that xRic-8 is participating in the immature oocyte by keeping Gsalpha-Gbetagamma-AC signaling complex in an activated state and therefore maintaining G2 arrest.[xRic-8, Gsalpha] (Mus musculus) PubMed

 385.

Results report that WNK3, another member of the WNK kinase family expressed by distal tubule cells, interacts with WNK4 and WNK1 to regulate NCC in both human kidney cells and Xenopus oocytes [NCC]. (Mus musculus) PubMed

 386.

demonstrated a critical requirement for XHSP27 in developing cardiac and skeletal muscle tissues[Hsp27] (Mus musculus) PubMed

 387.

Partitioning-defective (PAR1) is a conserved serine/threonine protein kinase implicated in the establishment of cell polarity [PAR1] (Mus musculus) PubMed

 388.

CDC2 protein kinase, Xenopus. CDC2 phosphoylation of BubR1 controls spindle checkpoint arrest and plk-mediated formation of the 3F3/2 epitope. (Mus musculus) PubMed

 389.

Sox3 genomic elements were identified and characterized and an element required for BMP-mediated repression via Vent1 and Vent2 proteins was identified through the use of transgenesis and computational analysis.[Vent1] (Mus musculus) PubMed

 390.

SUR1 and SUR2A randomly coassemble into functional K(ATP) channels [SUR1 and SUR2A] (Mus musculus) PubMed

 391.

We conclude that the SCFskp2 complex has functions in the control of neuronal differentiation additional to its role in cell cycle regulation. (SKP2 PROTEIN, XENOPUS) (Mus musculus) PubMed

 392.

TGIF2 is the molecular link between dorsoventral patterning of the endoderm and pancreatic specification.[TGIF2, Gata5] (Mus musculus) PubMed

 393.

Evolutionarily conserved glucocorticoid regulation of corticotropin-releasing factor expression.[CRF] (Mus musculus) PubMed

 394.

HVA L-type channel kinetics differ in relation to environmental changes in cellular secretory state, via intracellular Ca(2+)-buffering. Occurrence of LVA Ca(2+) channels depend on environment controlled channel gene expression [calcium channel, L-type]. (Mus musculus) PubMed

 395.

Analysis of collectrin expression in pronephroi at a variety of embryonic stages indicates that this gene is expressed at very high levels throughout the pronephric system, including proximal and distal segments and the Wolffian duct (collectrin). (Mus musculus) PubMed

 396.

suggest a role for importin alpha in regulating lamin assembly and possibly modulating the interactions of lamins with lamin-binding proteins[ lamin b3] (Mus musculus) PubMed

 397.

We propose that the main function of NEDD1 in Xenopus is in microtubule organization.(NEDD1 protein, Xenopus) (Mus musculus) PubMed

 398.

We have defined the proportion of GnRHRs at the cell surface. (GnRH receptor) (Mus musculus) PubMed

 399.

defined regions of Nup53 that bind to neighboring nucleoporins as well as those domains that target Nup53 to the nuclear pore complex (Nup53) (Mus musculus) PubMed

 400.

findings indicate that Activin/nodal signaling participates in regulation of XPAPC expression through a Smad binding element within the XPAPC promoter [XPAPC] (Mus musculus) PubMed

 401.

The amphibian sequence encodes a protein that is indeed a functional Na(+)/iodide symporter (NIS protein) in X. laevis, as well as R. catesbeiana [NIS protein]. (Mus musculus) PubMed

 402.

Cdk11 is responsible for RanGTP-dependent MT stabilization around chromosomes; this local stabilization is essential for normal rates of spindle assembly and spindle function.(CDK11 PROTEIN, XENOPUS) (Mus musculus) PubMed

 403.

Interactions between extracellular matrix molecule laminin beta2 and CaV2.2 calcium channel/Cacna1B regulate connectivity in the developing nervous system.(Cav2.2; cacna1B channel; calcium channel, voltage-dependent, N type, alpha 1B subunit) (Mus musculus) PubMed

 404.

Results suggest that Mitfalpha-M is involved in the regulation of melanosome transport and the level of dendricity in melanophores. (Mus musculus) PubMed

 405.

We conclude that importin beta, human or Xenopus, is an authentic negative regulator of nuclear assembly and, presumably, spindle assembly. (Importin beta, Xenopus) (Mus musculus) PubMed

 406.

Data show that HMGA2, a member of the HMGA sub-family of HMG proteins, has a critical function in cardiogenesis. (Mus musculus) PubMed

 407.

MKP3 can act to enhance DAT function and identifies MKP3 as a phosphatase involved in regulating dynamin-dependent endocy [DUSP6; SLC6A3] (Mus musculus) PubMed

 408.

Pituitary adenylate cyclase-activating polypeptide regulates brain-derived neurotrophic factor exon IV expression through the VPAC1 receptor in the amphibian melanotrope cell. [VPAC1 receptor] (Mus musculus) PubMed

 409.

findings document a critical role of VEGFR-3 in embryonic lymphatic development and function, and reveal a previously unrecognized modifier role of VEGF-D in the regulation of embryonic lymphangiogenesis in embryos (VEGF-D and VEGFR-3) (Mus musculus) PubMed

 410.

RGM A and neogenin have important functions during early neural development. [neogenin] (Mus musculus) PubMed

 411.

Tbx6 and mespb proteins interact physically with each other and regulate bowline expression. (mespb) (Mus musculus) PubMed

 412.

These results suggest that GPR3 moderates the oocyte response to maturation-promoting signals, and that gonadotropin-mediated activation of metalloproteinases may play a partial role in sensitizing oocytes for maturation.[GPR3] (Mus musculus) PubMed

 413.

Report elevation in heat shock protein 72 (HSP72) mRNA following contractions in isolated single skeletal muscle fibers. (Mus musculus) PubMed

 414.

Gene expression of upstream stimulatory factors, USF1 and USF2, was first detected as maternal transcripts and was observed continuously throughout embryonic development (USF1 and USF2). (Mus musculus) PubMed

 415.

ELYS chromatin capture recruits POM121 and NDC1 to initiate nuclear pore assembly (Mus musculus) PubMed

 416.

Data demonstrate that the cell adhesion molecule of the neuronal immunoglobulin superfamily DM-GRASP/ALCAM/CD166 is required for normal heart development in X. laevis. [DM-GRASP] (Mus musculus) PubMed

 417.

The accumulation of HSP110 in Xenopus laevis A6 kidney epithelial cells, was examined.[HSP110] (Mus musculus) PubMed

 418.

Mix.1/2 regulates levels and/or duration of FGF signals to which pronephros precursors are exposed during gastrulation[mix1] (Mus musculus) PubMed

 419.

p38 MAPK & CREB function along the dorsal-ventral axis in mesoderm patterning; the phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis & the p38 MAPK pathway mediates phosphorylation of CREB [p38 MAPK] (Mus musculus) PubMed

 420.

Eg5 diffuses along individual microtubules without detectable directional bias at close to physiological ionic strength. Eg5's motility becomes directional when bound between two microtubules.[Eg5] (Mus musculus) PubMed

 421.

matrix metalloproteinases 7, 9, and 18 are required in vivo for macrophage migration during embryonic development [MMP7] (Mus musculus) PubMed

 422.

Dynein-dynactin transports the essential motor Eg5 toward the spindle poles in Xenopus laevis egg extract spindles, revealing a direct interplay between two motors of opposite directionality.[Eg5, dynein, dynactin] (Mus musculus) PubMed

 423.

Data and preliminary model calculations suggest a faster turnover rate of PEPT1 in the presence of high substrate concentrations on the cytosolic surface [PEPT1]. (Mus musculus) PubMed

 424.

XSeb4R interacts directly with the 3'-UTR of VegT mRNA, stabilizes it, and stimulates translation. (VegT) (Mus musculus) PubMed

 425.

Left-sided heart-specific transcription of mouse galanin thus should be controlled by the left-right pathway[Galanin ] (Mus musculus) PubMed

 426.

HURP and TPX2 have nonredundant functions essential for chromatin-induced microtubule assembly.[HURP] (Mus musculus) PubMed

 427.

Data show that in Xenopus laevis oocytes, polar body emission requires a RhoA contractile ring and Cdc42-mediated membrane protrusion [RhoA]. (Mus musculus) PubMed

 428.

Results suggest that Ryk functions as an essential regulator for noncanonical Wnt11/frizzled 7-mediated endocytosis in the regulation of Xenopus laevis convergent extension movements [ryk]. (Mus musculus) PubMed

 429.

identify an essential role for Tgif1 in the control of nodal expression [ Tgif1 ] (Mus musculus) PubMed

 430.

identify Rspo3 as a novel, evolutionarily conserved angiogenic factor in embryogenesis[ R-spondin 3] (Mus musculus) PubMed

 431.

review mechanism of action and mode of regulation of Emi2, CSF function, and the general principles of APC/C regulation and control of protein function by MAPK pathways [review] [cytostatic factor, CSF] (Mus musculus) PubMed

 432.

Data suggest that ADAM cleavage of cadherin-11 promotes migration by modifying its ability to support cell-cell adhesion while maintaining the membrane-bound pool of beta-catenin associated with the cadherin-11 cytoplasmic domain [cadherin-11]. (Mus musculus) PubMed

 433.

Fgf8a induces NC indirectly through the activation of Wnt8 in the paraxial mesoderm, which in turn promotes neural crest (NC) formation in the overlying ectoderm primed by Bmp antagonists.[Fgf8a] (Mus musculus) PubMed

 434.

These experiments reveal a conserved role for maternally-encoded Irf6 in differentiation of a simple epithelium in X. laevis and D. rerio.[Irf6] (Mus musculus) PubMed

 435.

CaMKII turns on parallel pathways to activate the APC/C and to induce microtubule depolymerization at meiotic anaphase onset.[CamKII] (Mus musculus) PubMed

 436.

SGK1 might participate in the regulation of insulin secretion in part by controlling Kv1.5 surface abundance.[Kv1.5] (Mus musculus) PubMed

 437.

Data show that frg1 is expressed in and essential for the development of the tadpole musculature, and suggest that maintenance of normal FRG1 levels is critical for proper muscle development in frogs and humans [FRG1]. (Mus musculus) PubMed

 438.

XCTK2 has a role in controlling spindle length by cross-linking and sliding microtubules. (Mus musculus) PubMed

 439.

Results suggest that Rx-L, unlike Rx1, is required for the determination of retinal cell types, especially photoreceptors, rather than for proliferation of retinal progenitors [Rx-L]. (Mus musculus) PubMed

 440.

Chemical inhibition of Wee1 and Myt1 or expression of Cdk1 phosphorylation site mutants allows reversal to M phase even from late G1[cyclin-dependent kinase 1] (Mus musculus) PubMed

 441.

These results implicate MVP, and thus also vaults, in nuclear pore complexes (NPC)biogenesis.[MVP] (Mus musculus) PubMed

 442.

Strong ERK activation can target Cdc25A for degradation in a manner similar to, but independent of, Chk1 for cell cycle arrest.[ERK1] (Mus musculus) PubMed

 443.

Data show that Notch signaling acts downstream of foxD5 to promote the expression of a subset of neural ectodermal transcription factors; and Notch signaling and the foxD5 pathway maintain the neural plate in an undifferentiated state [foxD5]. (Mus musculus) PubMed

 444.

N- and E-cadherin play primary roles in F-actin assembly in addition to roles in cell adhesion, and that this function is specific to individual cadherins[E-cadherin] (Mus musculus) PubMed

 445.

These findings suggest that the MRN complex is a crucial mediator in the process whereby ATM promotes the TopBP1-dependent activation of ATR-ATRIP in response to double-stranded DNA breaks.[TopBP1] (Mus musculus) PubMed

 446.

TopBP1 directly recruits the 9-1-1 complex to stalled DNA replication forks. (Mus musculus) PubMed

 447.

The chromosomal distribution and dynamics of cohesin, the four-protein complex (RAD21/MCD1/SCC1, SMC1, SMC3, SCC3/SA2) responsible for sister chromatid cohesion, in Xenopus lampbrush chromosomes is characterized. RAD21, SMC1, SCC3. (Mus musculus) PubMed

 448.

MAPK signaling specifically modulates coupling mediated by Cx50 and that gap junctional communication and signal transduction pathways may interact in osmotic regulation during postnatal fiber development.[Cx50] (Mus musculus) PubMed

 449.

Data show that directionality and crosslinking are not the only characteristics for proper functioning of Kinesin-5 during spindle assembly in Xenopus egg extract; its motor domain properties are fine-tuned for its specific function [kinesin 5]. (Mus musculus) PubMed

 450.

Isovaleric, methylmalonic, and propionic acids have anesthetic effects in tadpoles and modulate alpha1 glycine receptor function. (Mus musculus) PubMed

 451.

FRG1 overexpression is capable of disrupting both the musculature and vasculature, recapitulating the two most prominent features of facioscapulohumeral muscular dystrophy.[FRG1] (Mus musculus) PubMed

 452.

Data suggest that Shroom 1-4 proteins play an important role in the morphogenesis of several different epithelial tissues during development [shroom 1, 2, 3, 4]. (Mus musculus) PubMed

 453.

These findings suggest a crucial role for the miR-430/427/302 family in vertebrate embryogenesis by controlling germ layer specification.[miR-427] (Mus musculus) PubMed

 454.

These findings highlight a specific role for XMEF2C in tendon development and identify a novel gene transactivation pathway where MEF2C cooperates with the bHLH protein, Xscleraxis, to activate specific gene expression. (Mus musculus) PubMed

 455.

The p24 proteins fulfil their role in secretory protein biosynthesis via COPI- or COPII-coated transport vesicles.[p24delta2] (Mus musculus) PubMed

 456.

Lhx1 plays fundamental roles in blastoporal region since the ancestral eumetazoan arose, it contributed as an 'original organizer gene' to evolution of vertebrate gastrula organizer, and Lhx3 is involved in establishment of organizer gene networks. [lhx1] (Mus musculus) PubMed

 457.

These results uncover new functions for TRAF4 as a Smurf1-regulated mediator of BMP and Nodal signaling that are essential for neural crest development and neural plate morphogenesis.[TRAF4, TGFB] (Mus musculus) PubMed

 458.

Sex-typical vocalizations most likely arise from activation of different populations of 5-HT(2C) receptor expressing cells or from differential activation of downstream pattern generating neurons [5-HT2C receptor] (Mus musculus) PubMed

 459.

CXCL14 expression in the ectoderm is regulated by both Bmp and canonical Wnt signaling[ CXCL14 ] (Mus musculus) PubMed

 460.

The results suggest that FLRT3, Unc5B and Rnd1 proteins interact to modulate cell adhesion in early Xenopus development.[Rnd1] (Mus musculus) PubMed

 461.

Results suggest that Xenopus MBD4/MLH1 participates in a novel G2 checkpoint that is responsive to DNMT1p levels in developing embryos and cells [Mbd4]. (Mus musculus) PubMed

 462.

Data demonstrate that XProfilin2 and XProfilin1 are non-redundant effectors for Daam1 for non-canonical Wnt signaling and that they regulate distinct functions during vertebrate gastrulation [profilin1]. (Mus musculus) PubMed

 463.

the cytoplasmic tail of Xcad-11 is both necessary and sufficient for proper cranial neural crest cell migration as long as it was linked to the plasma membrane[cad-11] (Mus musculus) PubMed

 464.

SPLUNC1 is secreted onto mucosal surfaces as a soluble volume sensor whose concentration and dilution can regulate ENaC activity and mucosal volumes, including that of airway surface liquid.[SPLUNC1, ENaC] (Mus musculus) PubMed

 465.

Report an adhesion-independent, aPKC-dependent function for E-cadherin in morphogenetic movements. (Mus musculus) PubMed

 466.

Shroom2/spectrin/dynactin-based mechanism controls pigment localization in amphibian eggs and that variation in maternal Shroom2 mRNA levels accounts in part for variation in amphibian egg pigment patterns during evolution.[Shroom2] (Mus musculus) PubMed

 467.

Dazap2 is a novel and essential branch of FGF-induced neural patterning.[Dazap2] (Mus musculus) PubMed

 468.

Data suggest that both aPKC and Lgl2 affect cell fate, but that aPKC is a nuclear determinant itself that might shuttle from the membrane to the nucleus to control cell proliferation and fate [Lgl2, aPKC]. (Mus musculus) PubMed

 469.

PIP(2) stimulates NBCe1-A activity, and phosphoinositides are regulators of bicarbonate transporters [NBCe1] (Mus musculus) PubMed

 470.

Data show that Mind bomb (Mib), a ubiquitin ligase that promotes Notch ligand trafficking and activity, is a crucial molecular substrate for PAR-1 and is involved in neurogenesis [Mib, Par-1]. (Mus musculus) PubMed

 471.

suggests that Mre11-Rad50-Nbs1 inactivation participates in the down-regulation of damage signaling during checkpoint recovery following double-strand breaks repair.[Mre11] (Mus musculus) PubMed

 472.

These results demonstrate an essential role for Myo10 in normal cranial neural crest migration and suggest a link to cell-cell interactions and formation of processes [myosin 10]. (Mus musculus) PubMed

 473.

Xiwi associates with translational regulators in an RNA-dependent manner, but Xenopus tudor interacts with Xiwi independently of RNA.[Piwi homologue] (Mus musculus) PubMed

 474.

Results suggest that Frizzed 10 mediates Wnt1 signalling to determine sensory neural differentiation in Xenopus in vivo and in mouse cell culture [frizzled 10b]. (Mus musculus) PubMed

 475.

Transport along actin filaments and the switching from actin to microtubule networks are regulated by changes in the diffusion time between periods of active motion driven by myosin-V. [myosin-V] (Mus musculus) PubMed

 476.

analysis of CLIP-170-dependent capture of membrane organelles by microtubules initiates minus-end directed transport [CLIP170] (Mus musculus) PubMed

 477.

work links the onset of zygotic gene expression in the Xenopus embryo with the translocation of Smicl from cytoplasm to nucleus, the phosphorylation of Rpb1 and the 3'-end processing of newly transcribed mRNAs.[Smicl and Rpb1] (Mus musculus) PubMed

 478.

demonstrate that the maternal mRNAs for cyclins A1 and B2 each contain a single miR-427 target sequence, spanning less than 30 nucleotides, that is both necessary and sufficient for deadenylation.[miR-427] (Mus musculus) PubMed

 479.

Position of Pro and Ser near Glu7.32 in the extracellular loop 3 is critical for the differential ligand selectivity between mammalian and nonmammalian GnRHRs. [GnRH-II] (Mus musculus) PubMed

 480.

Membrane-proximal expression of the cytoplasmic domain of Ig alpha supports early B cell development as efficiently as the intact B cell receptor complex. [CD79A antigen (immunoglobulin-associated alpha), mb-1] (Mus musculus) PubMed

 481.

Bves may play a role in cell adhesion and movement of epithelia during early embryogenesis [Bves] (Mus musculus) PubMed

 482.

H2A histone family, member B3 (H2ABbd) confers lower stability to the nucleosome [H2ABbd] (Mus musculus) PubMed

 483.

MURF-2 has roles in microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development [MURF-2, also called TRIM55 or RNF29] (Mus musculus) PubMed

 484.

the complex of Nished, NFATc4, and co-activator p300 bound to the intronic regulatory element has a role in upregulating myosin light chain-2v in cardiac hypertrophy [NFATc4] (Mus musculus) PubMed

 485.

Hoxd10 expression is sufficient to induce LS motoneuron identity and axon trajectories characteristic of motoneurons in the LS region [Hox10d] (Mus musculus) PubMed

 486.

Alterations in mature SREBP-1 play role in mediating effects of starvation and feeding high-carbohydrate, low-fat diet on acetyl-CoA carboxylase-alpha transcription in chick liver. (Sterol regulatory element-binding protein-1) (Mus musculus) PubMed

 487.

OCTN3 protein was mainly associated with the basolateral membrane of enterocytes [OCTN3] (Mus musculus) PubMed

 488.

Sab is associated with the mitochondria and co-localizes with a portion of active JN kinase after stress treatment. (Sab--SH3BP5) (Mus musculus) PubMed

 489.

RasGRP3 undergoes phosphorylation at Thr-133 upon B cell receptor cross-linking, thereby resulting in its activation (RasGRP3) (Mus musculus) PubMed

 490.

Antigen receptor activation of wild type PKD is dependent on phospholipase C (PLC)/diacylglycerol (DAG) and PKC, whereas PKD-S744E/S748E is only dependent on PLC/DAG but no longer requires PKC [phospholipase C gamma 2] (Mus musculus) PubMed

 491.

The chicken proglucagon gene is composed of seven exons, and contains an additional exon that contains much of intervening peptide 1 that has not been seen in any other proglucagon gene. (Mus musculus) PubMed

 492.

effect of dietary protein intake and stage of development on chicken intestinal peptide transporter (cPepT1) mRNA abundance. (cPepT1) (Mus musculus) PubMed

 493.

Activation of mGluR5 may modulate L-type voltage-gated Ca2+ current in these GABAergic amacrine cells via activation of protein kinase A, possibly via direct activation of a Ca2(+)-dependent adenylate cyclase. (mGlur5) (Mus musculus) PubMed

 494.

Data suggest that Sox9 and Nkx2.5 are regulated independently by bone morphogenetic protein signaling, and act coordinately to specify the pyloric sphincter. (Mus musculus) PubMed

 495.

activation and repression of FGFR1 gene transcription is governed by interplay between Sp1, p107, p130, and E2F4 in distinct transcriptional complexes during skeletal muscle development [FGFR1, E2F4, p107] (Mus musculus) PubMed

 496.

The anterior region-specific expression of mario corresponds well with the presence of digit 2, and fate map analysis showed that mario expression at early stages represents the presumptive digit 2 region [mario] (Mus musculus) PubMed

 497.

Agouti signaling (ASIP) genes exist in many species in lower vertebrates and were most probably present in early stages of vertebrate evolution. (agouti-signaling peptide; ASIP) (Mus musculus) PubMed

 498.

Prx1a:Prx1b ratio and the alternative splicing mechanism that generates these two isoforms are critical in controlling chondrogenesis [Prx1a and Prx1b] (Mus musculus) PubMed

 499.

Nrf3, adjacent to the Hox A cluster, is expressed during early development of the chicken embryo(NRF-3 protein) (Mus musculus) PubMed

 500.

Interaction of steroid receptorss with chicken-transfected hsp90 is minimal when compared to a bona fide type of interaction, with the co-factors. (Mus musculus) PubMed

 501.

in the neural retina, expression is restricted to the ventricular zone, where the cell bodies of retinal progenitor cells reside. (cRPTPlambda AND cRPTPpsi) (Mus musculus) PubMed

 502.

a crucial role of Cdk5 in elongation and maintenance of axons as well as for stability and steering of their growth cones. (cdk35) (Mus musculus) PubMed

 503.

Proneural proteins promote neurogenesis by upregulating Sox21. Key role for Sox21 in progression of neuronal differentiation. Important role of proneural proteins is capacity to upregulate Sox21. (Mus musculus) PubMed

 504.

Results failed to demonstrate co-assembling of GATA factors or SCL with Lmo2. While overlapping expression of GATA-2/3 and SCL was detected, Lmo2 activation could not be demonstrated in neural cells in investigated period of neuronal development. (SCL) (Mus musculus) PubMed

 505.

Cbfbeta and Runx1 display multiple combinatorial patterns in the endoderm and in specific nerves or ganglia.(Runx1) (Mus musculus) PubMed

 506.

Results demonstrate a crucial role for NrCAM in the navigation of retinal ganglion cell axons in the developing retina towards the optic fissure, and also for pathfinding into the optic nerve [NrCAM]. (Mus musculus) PubMed

 507.

PHI-1 may act as a CPI-17 analog in chicken smooth muscle and inhibit myosin phosphatase activity during G-protein stimulation to produce Ca2+ sensitization. (Mus musculus) PubMed

 508.

This study show that distinct tissue competence to express Mkp3 rostrally and caudally to the zona limitans intrathalamica (ZLI). (Mus musculus) PubMed

 509.

Commissural neurons from chicken embryos expressing a dominant-negative PlTPalpha mutant show reduced axon outgrowth. These results identify a crucial role for PlTPalpha in netrin-1-induced neurite outgrowth. [PITPalpha] (Mus musculus) PubMed

 510.

talpid2 is likely to have a tissue-autonomous, bidirectional (positive and negative) role in hedgehog (HH) signaling [talpid2] (Mus musculus) PubMed

 511.

isolation and molecular characterization of the chick ortholog of nyctalopin (NYX), the gene responsible for X-linked complete congenital stationary night blindness (Mus musculus) PubMed

 512.

Sema5A is expressed in the newly formed atrioventricular valves in the embryonic heart [Sema5A] (Mus musculus) PubMed

 513.

findings revealed that phospho-CREB is specifically expressed in a previously unreported myelin-associated protein of oligodendrocytes[CREB] (Mus musculus) PubMed

 514.

AWAK. Chick intestine contains a novel 767 amino acid avian protein which has a proposed molecular weight of 81kDa. The presence of WAP and Kunitz modules suggests that AWAK has proteinase inhibitor activity. (Mus musculus) PubMed

 515.

ALG-2. The interaction of the ALG-2/Alix complex with TSG101 and CHMP4b is necessary for naturally occurring death of motoneurons. (Mus musculus) PubMed

 516.

Role of GDF-5 in cavitation was shown. (Mus musculus) PubMed

 517.

Neuropeptide Y content in chick embryo hypothalamus during development. (Mus musculus) PubMed

 518.

The reciprocal expression of heat shock transcription factor 1 (HSF1) and heat shock transcription factor 3 (HSF3) in blood and brain in response to heat exposure is reported. [HSF1; HSF3] (Mus musculus) PubMed

 519.

Muscularization of cushion-derived mesenchymal tissues in embryonic heart is associated with a discrete genetic program reflected by the expression of h1-calponin. [h1-calponin] (Mus musculus) PubMed

 520.

redistribution of PS is dependent on an increase in phospholipid scramblase activity and a decrease in APLT activity.Lastly,we show that translocator activity is likely to be modulated by membrane cholesterol levels through a membrane raft microdomain (Mus musculus) PubMed

 521.

The presence of MMP-9 enzyme was negatively correlated with the presence of TIMP-1 enzyme [TIMP-1] (Mus musculus) PubMed

 522.

Shh contributes to CDC25B transcriptional activation in the neural tube both of chick and mouse embryos (CDC25B) (Mus musculus) PubMed

 523.

The acquisition of DNA (cytosine-5-)-methyltransferase 3-like(DNMT3L) by a common ancestor of eutherians and marsupials might have been closely related to the evolution of imprinting. (DNMT3L) (Mus musculus) PubMed

 524.

Several proteins associated with the egg shell membranes (ESM) with antibacterial activity have been identified including beta-N-acetylglucosaminidase (beta-NAGase)and pure fractions of beta-NAGase were obtained from egg white. [beta-NAGase] (Mus musculus) PubMed

 525.

biochemical behavior of di-N-acetylchitobiase indicates it has three subsites, -2, -1, +1, in which the reducing-end trimer of any sized chitooligosaccharide is bound. The +1 site is specific for an alpha-anomer [di-N-acetylchitobiase] (Mus musculus) PubMed

 526.

TSK isoforms play a crucial role in chick axis formation by locally modulating VG1 and BMP activities during gastrulation.(VG1) (Mus musculus) PubMed

 527.

May be involved in regulating the development and functional maturation of the pineal gland. (Islet-1) (Mus musculus) PubMed

 528.

isolated a homologue of BM88, a cell-intrinsic nervous system-specific protein and examined the expression of BM88 mRNA and protein in the developing nervous system of the embryo by in situ hybridization and immunohistochemistry (BM88) (Mus musculus) PubMed

 529.

The expression of the chick four-jointed (fjx) homologue during embryonic development was determined. (Mus musculus) PubMed

 530.

Our data indicate that Muller cells in the chicken retina possess 11-cis-ARAT activity, thus providing an explanation for the accumulation of 11-cis-retinyl esters in the cone cycle[11-cis acyl-CoA:retinol O-acyltransferase] (Mus musculus) PubMed

 531.

Data show that Notch2, Hey1 and Hey2 initiate a signaling cascade that delimits the non-chamber atrioventricular canal (AVC) and inner curvature (IC) regions of the developing heart [Hey1, Hey2] (Mus musculus) PubMed

 532.

PHI-1 inhibits myosin light chain phosphatase by interacting with the active site of PP1c to produce a Ca(2+) independent increase in myosin light chain(20) phosphorylation and force[PHI-1, myosin light chain(20) and myosin light chain phosphatase] (Mus musculus) PubMed

 533.

investigated the domain requirements and transcriptional activities associated with Dlx5- and Dlx6-mediated chondrogenesis[Dlx6] (Mus musculus) PubMed

 534.

fibroblast growth factor (FGF), FGF8-soaked beads induce ectopic mkp3 expression, indicating that apical ectodermal ridge apical ectodermal ridge-derived FGF8 protein may activate mkp3 in the distal mesenchyme[mkp3] (Mus musculus) PubMed

 535.

Results describe the gene expressions of taurine transporter and taurine biosynthetic enzyme during mouse and chicken embryonic development [taurine transporter]. (Mus musculus) PubMed

 536.

in addition to thecal perlecan, ggBM1 is involved in the transfer of yolk precursors from the thecal capillary bed to oocyte surface lipoprotein receptors mediating their uptake into oocytes [ggBM1] (Mus musculus) PubMed

 537.

The present findings show that the interaction between PKCgamma and GluR4 is specifically required to assure PKC-driven phosphorylation and surface membrane expression of GluR4.[PKCgamma] (Mus musculus) PubMed

 538.

These findings collectively show for the first time that multiple MMPs, ADAMs, and TIMPs appear to functionally interact during corneal development.[TIMP1] (Mus musculus) PubMed

 539.

These results suggested that lysophosphatidic acid in hen egg white is produced from lysophospholipids, especially LPC, by the action of ATX/lysoPLD, possibly originating from hen oviduct fluid.[Lysophospholipase D] (Mus musculus) PubMed

 540.

CYP1B1 is one of the RALDH-independent components by which embryos direct Retinoic Acid-mediated patterning. [CYP1B1] (Mus musculus) PubMed

 541.

function of miR-124 during spinal cord development; miR-124 appears to ensure that progenitor genes are post-transcriptionally inhibited in neurons [miR-124] (Mus musculus) PubMed

 542.

Reelin-expressing primary retinal cultures were used to investigate the role of the four Dab1 tyrosine phosphorylation sites on overall tyrosine phosphorylation, Dab1 phosphorylation, Src family kinase activation and neurite formation.[Dab-1] (Mus musculus) PubMed

 543.

The ability of supplementation of Freund adjuvant to enhance the quantity of specific immunoglobulin Y in eggs of laying hens. [immunoglobulin Y IgY] (Mus musculus) PubMed

 544.

alpha-MSH causes behavioral effects that may secondarily affect feed intake at a low magnitude and may modulate the behavioral effects of NPY in chicks, contributing to the overall effect on feed intake [alpha-MSH] (Mus musculus) PubMed

 545.

analysis of expression patterns of chick Musashi-1 in the developing nervous system [Musashi-1] (Mus musculus) PubMed

 546.

specific H1R variant plays a unique and important role in the DNA damage response in vertebrates. (Mus musculus) PubMed

 547.

Data show that on binding of Slit to Robo, the adaptor protein Cables is recruited to Robo-associated Abl and forms a multimeric complex by binding directly to N-cadherin-associated beta-catenin [Robo, Cables]. (Mus musculus) PubMed

 548.

fesselin is a natively unfolded protein [fesselin] (Mus musculus) PubMed

 549.

cHS4 insulator counteracts telomeric position effects in an upstream stimulatory factor-independent manner [cHS4] (Mus musculus) PubMed

 550.

Intracerebroventricular neuropeptide S causes anorexigenic effects in chicks, without directly affecting water intake, and the hypothalamus is involved. (Mus musculus) PubMed

 551.

Retinal dehydrogenase 1 (RALDH1) mRNA levels in the chick duodenum increased during the postnatal period, indicating a similar developmental expression pattern to that of BCMO1. (Mus musculus) PubMed

 552.

These studies on the biochemical characterization of the recombinant proteins suggest the interdependence of the two domains for proper organization of the riboflavin binding pocket.[Riboflavin carrier protein] (Mus musculus) PubMed

 553.

ZBP2, a homologue of the splicing factor KSRP, binds initially to nascent beta-actin transcripts and facilitates the subsequent binding of the shuttling ZBP1.[ZBP1, ZBP2] (Mus musculus) PubMed

 554.

This study found that tissue hypoxia is likely a normal component of embryonic development in the chicken based on the upregulation of hypoxia response genes, including hypoxia upregulated protein 1(HUP1).[HUP1] (Mus musculus) PubMed

 555.

PTPsigma can thus show differential complex formation with different Trk family members and in neurons can selectively target the neurite-forming signalling pathway driven by TrkA.[PTPsigma] (Mus musculus) PubMed

 556.

a novel role for Cad6B in controlling the proper timing of neural crest emigration and delamination from the neural tube of the avian embryo. (Mus musculus) PubMed

 557.

A 2.0 A resolution crystal structure of myristoylated GCAP1 with Ca(2+) bound (GCAP1). (Mus musculus) PubMed

 558.

Thyroid receptor beta 0 (TRbeta0) trimers have DNA recognition and transcriptional regulatory properties that are not observed for dimers. (Mus musculus) PubMed

 559.

The vertebrate KNL1 counterpart is essential for chromosome segregation and is required to localize a subset of outer kinetochore proteins.[KNL1] (Mus musculus) PubMed

 560.

Sema6A acts as a gate keeper between the PNS and the CNS both ventrally and dorsally. (SEMA6A, CHICKEN) (Mus musculus) PubMed

 561.

These findings demonstrate, for the first time, the contribution of Isl1(+) splanchnic mesoderm cells to a subset of branchiomeric skeletal muscles.[Islet-1] (Mus musculus) PubMed

 562.

partial cloning, characterization and tissue distribution of chicken 11beta-hydroxysteroid dehydrogenase type 2. (Mus musculus) PubMed

 563.

closely related adhesion molecules--Dscam, DscamL, Sidekick-1 and Sidekick-2--are expressed in chick by non-overlapping subsets of interneurons and RGCs that form synapses in distinct IPL sublaminae [DscamL] (Mus musculus) PubMed

 564.

The regulation of S6K1 differs between the liver and muscle and between chickens divergently selected for growth. There is a potential involvement of S6K1 in the control of muscle growth and an open issue concerning S6K1 function in chicken liver [S6K1] (Mus musculus) PubMed

 565.

helical and kinase domain mutations act synergistically when present in the same p110alpha molecule[p110alpha of phosphatidylinositol 3-kinase] (Mus musculus) PubMed

 566.

Cdk6 up-regulation in TDP-43-depleted cells is accompanied by an increase in phosphorylation of two of its major targets, the retinoblastoma protein pRb and pRb-related protein pRb2/p130. TDP-43] (Mus musculus) PubMed

 567.

Par6/Smurf1/RhoA have roles in regulating EMT in endocardial cells (Mus musculus) PubMed

 568.

A key role for phospholipase C-gamma2 (PLCgamma2), Vav, B cell linker, and Bruton's tyrosine kinase in the formation of highly coordinated "microsignalosomes," , is identified.[Plcgamma2] (Mus musculus) PubMed

 569.

A report on the isolation and expression pattern of the Sizzled gene in the chick embryo (Sizzled). (Mus musculus) PubMed

 570.

In the embryonic heart, JNK activity exhibits a characteristic pattern during anoxia and reoxygenation and the respective open-state of ion channels can be a major determinant of JNK activity.[mtioKATP, JNK] (Mus musculus) PubMed

 571.

HC progenitors are sensitive to follistatin and become committed to produce Lim1+ HC subtypes concomitantly with or early after their own generation [Lim1] (Mus musculus) PubMed

 572.

findings are consistent with mGluR1 activating inositol (1,4,5)-trisphosphate receptors to release intracellular Ca(2+) required for long-term memory formation and have been interpreted within a long term potentiation 2 model[MGLUR1] (Mus musculus) PubMed

 573.

TGF-beta1, TGF-beta2, TGF-beta3 have different roles in the embryonic nervous system of mouse and chicken [TGF-beta1] (Mus musculus) PubMed

 574.

results provide evidence for the important role of vasotocin receptor VT2 in mediating effects of arginine vasotocin on endocrine secretion from corticotropes and, partially, from lactotropes [VT2R] (Mus musculus) PubMed

 575.

misexpression of the EWS-FLI1 oncogene in neural crest-derived stem cells may be an initiating event in ESFT genesis.(EWS-FLI1) (Mus musculus) PubMed

 576.

DNA binding and functional assays revealed that the 5'-UTR has a consensus neuron-restrictive silencing element that binds NRSF, and a SP element that binds SP3, both repressing Grin1 transcription in undifferentiated P19 cells and PC12 cells. [NRSF] (Mus musculus) PubMed

 577.

Results show that the serine/threonine kinase death-associated protein kinase (DAPK) is involved in the signal transduction of neogenin [DAP kinase]. (Mus musculus) PubMed

 578.

Data show that SynCAM is expressed in the chick ciliary ganglion, embedded in a nicotinic pathway, and, as shown previously for neuroligin and L1-CAM, acts transcellularly to promote synaptic maturation on the neurons in culture [synCAM]. (Mus musculus) PubMed

 579.

Results provide evidence for 11beta-hydroxysteroid dehydrogenase type 1 as a tissue-specific regulator of glucocorticoid action in non-mammalian vertebrates [11HSD1]. (Mus musculus) PubMed

 580.

The 1.8-A-resolution crystal structure of the CHIR-AB1 ectodomain, is described.[CHIR-AB1] (Mus musculus) PubMed

 581.

Gonadotrophin-inhibitory hormone receptor (GnIHR) expressed in FSHbeta or LHbeta mRNA-containing cells is likely to mediate the inhibitory effect of GnIH on LH and FSH secretion.[Gonadotrophin-inhibitory hormone receptor] (Mus musculus) PubMed

 582.

Short time exposure to hypoxia increases DNA synthesis in primary cultured chicken hepatocytes through cooperation of Ca2+/PKC, p38 MAPK, p44/42 MAPKs, and PI3K/Akt pathways.[mTOR protein] (Mus musculus) PubMed

 583.

NP25 plays a dynamic role in the regulation of neurite growth. (Mus musculus) PubMed

 584.

Data show that Art7.1 was predominantly expressed on the surface of B cells from the bursa of Fabricius as a GPI-anchored form, as well as on T cells from the thymocytes [Art7.1]. (Mus musculus) PubMed

 585.

Expression of full-length human NMHC-IIA and -IIB in 10 T1/2 cells demonstrated that flectin antibody recognizes both isoforms (Mus musculus) PubMed

 586.

ENOX2 may fulfill some functions essential to the growth of early embryos which are lost in late embryo stages and absent from normal adult cells but which then reappear in cancer. (Mus musculus) PubMed

 587.

FKBP65 is also able to interact with triple helical collagen, and acts as a collagen chaperone[ FKBP65 ] (Mus musculus) PubMed

 588.

local structural changes in the protein due to cation binding or ligand binding (protonation)[acid sensing ion channel-1] (Mus musculus) PubMed

 589.

In skeletal muscle, fesselin was associated with desmin in regularly spaced bands distributed along the length of muscle fibers suggesting localization to the Z-line. [fesselin] (Mus musculus) PubMed

 590.

Study determined the crystal structure of CG-1B; position of the Trp ring in the lectin site, presence of only 2 ordered water molecules therein, and changes in interface region between the 2 subunits, set the structure of CG-1B apart from CG-1A.[CG-1B] (Mus musculus) PubMed

 591.

These findings indicate that the CAV promoter activity can be affected directly or indirectly by COUP-TF1 and deltaEF1. [COUP-TF1] (Mus musculus) PubMed

 592.

These results suggest that neurogenin 3 (ngn3) regulates retinal neurogenesis by inducing regulatory genes for early-born neurons and repressing those for later-born cells [ngn3]. (Mus musculus) PubMed

 593.

IL-6 stimulates the proliferation of primary cultured chicken hepatocytes through PKC, p44/42 MAPKs, and PPARdelta pathways.[PPARdelta, Mapk3] (Mus musculus) PubMed

 594.

The Fcupsilon3-4 structure reveals features common to both IgE-Fc and IgG-Fc, and the implications for IgY binding to its receptor are discussed.[IgY] (Mus musculus) PubMed

 595.

TGF-beta1 inhibits skeletal muscle growth by regulating MyoD and myogenin expression [transforming growth factor-beta1] (Mus musculus) PubMed

 596.

The expression pattern of IP(3)R contributes to the formation of specialized calcium release-activated calcium current stores in B cells.[IP3 receptor] (Mus musculus) PubMed

 597.

These studies suggest that portions of the KV4.2 T1 domain can act as docking sites for proteins such as PPTX, further underscoring the significance of this domain.(KV4.2 protein, chicken) (Mus musculus) PubMed

 598.

Patch-clamp photometry was used to determine the contribution of Ca(2+) to total current through native and recombinant ASIC1a receptors.[ASIC1a] (Mus musculus) PubMed

 599.

Cyclic mechanical stretch increased cardiomyocyte (CM), but not non-CM, proliferation and increased p38MAPK phosphorylation.[p38MAPK] (Mus musculus) PubMed

 600.

These findings reveal that retinoid and Sema6A/PlexA4 signaling pathways intersect through FARP1 to control dendritic growth(Farp1 protein, chicken) (Mus musculus) PubMed

 601.

The normal FOP protein localizes at the centrosome throughout the cell cycle and preferentially accumulates at the distal end of the mother centriole.[FOP] (Mus musculus) PubMed

 602.

At the calyciform synapse, rapid synaptic transmission is mediated apparently without participation of ionotropic receptors concentrated at postsynaptic densities.[alpha3-nAChR, alpha7-nAChR] (Mus musculus) PubMed

 603.

The complex of YF1*7.1 heavy chain and beta(2)-microglobulin was reconstituted and purified without a peptide.[YF1*7.1] (Mus musculus) PubMed

 604.

Expression of arginine vasotocin receptor 2 (VT2R) in the pituitary was increased in chickens with 2-thiouracil-induced hypothyroidism; expression of VT2R in the pituitary was decreased by water deprivation of such birds [VT2R] (Mus musculus) PubMed

 605.

results indicate that myostatin and peroxisome-proliferator-activator-gamma-coactivator-1alpha(PGC-1alpha) expression in the skeletal muscle rapidly change in response to acute cold(PGC-1alpha) (Mus musculus) PubMed

 606.

Although the complete helicase domain is critical for crosslink repair, a predicted inactivating mutation of the Walker B box domain has no impact on Fanconi Anaemia pathway associated functions (FANCM). (Mus musculus) PubMed

 607.

Akt activity can regulate growth cone expansion via localized Rac1 signaling and regulate axonal branching and soma size via activation of mTOR. (Mus musculus) PubMed

 608.

Retinal pigment epithelium morphogenesis and cytodifferentiation requires SoxB1 downregulation.[SoxB1] (Mus musculus) PubMed

 609.

The expression of this gene varied from tissue to tissue. The study with labelled green fluorescence showed that the protein mainly concentrated in the nucleus. (Mus musculus) PubMed

 610.

These data suggested that the apoptotic effect of transforming growth factor-beta1 on satellite cells is likely associated with a beta1 integrin-mediated focal adhesion kinase signaling pathway.[beta1 integrin] (Mus musculus) PubMed

 611.

Results identified a centromere protein S (CENP-S)-containing subcomplex that includes the new constitutive kinetochore protein CENP-X [CENP-X, -S]. (Mus musculus) PubMed

 612.

Epigenetic mechanisms are necessary for in vivo chicken alpha-globin gene switching through differential gene silencing of the embryonic alpha-globin gene in order to allow proper activation of adult alpha-globin genes.[Pi globin] (Mus musculus) PubMed

 613.

3BP2 induces the protein complex with cellular signaling molecules through phosphorylation of Tyr(183) and SH2 domain leading to the activation of NFAT in B cells [3BP2] (Mus musculus) PubMed

 614.

The effect of dietary phenylalanine on the activity of phenylalanine-pyruvate aminotransferase (PAT) activity in broiler chicks is reported.[PAT] (Mus musculus) PubMed

 615.

A study evaluating the tissue distribution and relationship to aging of xanthine oxidoreductase (XOR) in broiler chicks is reported.[XOR] (Mus musculus) PubMed

 616.

The novel gene, OSU-T1-50 displayed a very dynamic enhancement of gene expression during trophoblastic elongation. It may play an important role in trophoblastic elongation[OSU-T1-50] (Mus musculus) PubMed

 617.

LLC-PK1 cells transport L-leucine through Na+-independent pH-insensitive and high-affinity LAT1 transporter and L-DOPA through Na+-independent pH-insensitive and low-affinity LAT2 transporter. (LAT1, LAT2) (Mus musculus) PubMed

 618.

the p38 MAPK is an upstream component of Akt-mediated eNOS activation [p38 MAPK; Akt kinase] (Mus musculus) PubMed

 619.

identified a secretolytin-like peptide (KR-11, pCgB(637-647)) from porcine chromaffin granules[KR-11 peptide] (Mus musculus) PubMed

 620.

Data suggest that force suppression is mediated by phosphorylation of heat shock protein 20, resulting full or partial inhibition of local myosin binding at the thin- or thick-filament level. (Mus musculus) PubMed

 621.

is involved in the meiotic maturation of mammalian oocytes, and blocking Cdk2 activity results in the failure of cyclin B1 accumulation and second meiosis induction (Mus musculus) PubMed

 622.

results suggest that the N-glycans located in the N-terminal half of the zona pellucida domain of porcine zona pellucida B glycoprotein(ZPB) are involved in sperm-zona binding (Mus musculus) PubMed

 623.

Piglets infected with E coli O55 showed a significant increase of plasma calprotectin and the highest mean level of calprotectin in the bronchoalveolar lavage, which was coincident with septicaemia [calprotectin] (Mus musculus) PubMed

 624.

Knockout of this enzyme in pigs makes it possible to transcend barriers for heart transplantation (alpha1,3-galactosyltransfesrase) (Mus musculus) PubMed

 625.

Chemokines acting via CXCR2 and platelet-activating factor are released by porcine endothelial cells inducing efficient chemotaxis of human neutrophils. (CXR2, platelet activating factor) (Mus musculus) PubMed

 626.

Data suggest that polarized, shear stress-induced signaling from focal adhesions at the upstream lamellae,leads to the local inactivation of Rac1 by inhibiting paxillin and p130CAS phosphorylation [paxillin, p130CAS, Rac1]. (Mus musculus) PubMed

 627.

Genetic variability is assocated with reproductive traits. (ESR genes) (Mus musculus) PubMed

 628.

Enzyme-mediated cardioprotection after ischemia-reperfusion involves, at least in part, the phosphatidylinositol 3-kinase/AKT pathway [AKT] (Mus musculus) PubMed

 629.

The number of calretinin and reelin-positive neurons decreased from 1 day to one year. (Reelin and calretinin) (Mus musculus) PubMed

 630.

developmental change in PKB activation is isoform specific and involves regulation by PDK-1 [PDK-1, PKBalpha, PKBbeta] (Mus musculus) PubMed

 631.

hypoxia induces overexpression of alphaB crystallin in the gastrointestinal tract of the newborn piglet [alphaB crystallin] (Mus musculus) PubMed

 632.

Nuclear Mitotic Apparatus (NuMA) protein is contributed by the donor cell nucleus in cloned porcine embryos [NuMA] (Mus musculus) PubMed

 633.

These data indicate that Ang-(1-7) inhibits the proximal tubule Na+-ATPase by interaction with the AT2 receptor that subsequently activates the G(i/o) protein/cGMP/PKG pathway.[Na AtPase] (Mus musculus) PubMed

 634.

Activation of Rac1 and inhibition of RhoA restored the abnormal phenotype and permeability of hypertensive pulmonary artery endothelial cells to normal. (Rac1 AND RhoA) (Mus musculus) PubMed

 635.

Upregulation mechanisms underlying the B1 receptor takes place in an ocular tissue, the pig iris sphincter. (bradykinin b1 receptor) (Mus musculus) PubMed

 636.

existence of Amylo-1,6-glucosidase as well as glycogen phosphorylase in the brain explains brain glycogenolysis fully and supports the hypothesis that glycogen is a significant source of energy in this organ [Amylo-1,6-glucosidase ] (Mus musculus) PubMed

 637.

genomic structure and a novel alternatively spliced forms [pre-T cell receptor alpha] (Mus musculus) PubMed

 638.

results suggest that the proteolysis of securin is dependent on ubiquitin-proteasome pathway and is necessary for the degradation of Rec8 during meiotic metaphase-to-anaphase transitions in oocytes [securin, Rec8] (Mus musculus) PubMed

 639.

evidence that neonatal uterine expression of LGR7 & LGR8 is detectable at birth, is regulated developmentally during an established critical period for estrogen-sensitive uterine programming & is stimulated by estrogen exposure [LGR7,LGR8] (Mus musculus) PubMed

 640.

glycolysis starts at concrete points in the boar-sperm surface[ADP-dependence of pyruvate kinase] (Mus musculus) PubMed

 641.

signaling by RA via RA receptors regulates the expression of NRL, providing a framework for delineating early steps in photoreceptor cell fate determination [photoreceptor transcription factor NRL] (Mus musculus) PubMed

 642.

results implicate TNFalpha and TNFalpha-RII as important actors in both the acute and the chronic phases of inflammation following stent implantation [TNFalpha receptor II] (Mus musculus) PubMed

 643.

A study of the mapping characteristics and relationship to body composition of FAT1 and FABP4 in swine is reported.[FAT1] (Mus musculus) PubMed

 644.

electrons from the electron transfer flavoprotein(ETF) flavin semiquinone may enter the ETF-ubiquinone oxidoreductase flavin one by one, followed by rapid equilibration with the cluster[Electron transfer flavoprotein-ubiquinone oxidoreductase] (Mus musculus) PubMed

 645.

CD4(-) gammadelta thymocytes that can be further subdivided according to their CD2/CD8alphaalpha phenotype[TCRgammadelta] (Mus musculus) PubMed

 646.

the presence of the halothane gene induced early energy depletion, which could be a primary reason causing AMPK activation, leading to accelerated glycolysis and an increased incidence of PSE meat [AMPK & Porcine Stress Syndrome gene] (Mus musculus) PubMed

 647.

These results suggest that lysoPAF was degraded by high ecto-lysophospholipase C activity.[Lysophospholipase C] (Mus musculus) PubMed

 648.

Perturbing the amount of Smarca 2 in porcine embryos disrupts cleavage development. (Mus musculus) PubMed

 649.

Hepatocyte nuclear factor 4 alpha (HNF-4 alpha)induces apoliprotein IV gene in response to dietary lipids in the intestine. (Mus musculus) PubMed

 650.

The MUC4 g.243A>G mutation is strongly associated with susceptibility to enterotoxigenic Escherichia coli F4ab/ac infection. (Mus musculus) PubMed

 651.

New role for PBR which could be a major target in the regeneration process during ischemia reperfusion. (PBR, peripheral-type benzodiazepine receptor) (Mus musculus) PubMed

 652.

This study suggested closer links between the release of haptoglobin, Pig-MAP and monocytes compared to the release of AGP, serum amyloid A and transthyretin.[Pig-MAP; serum amyloid A] (Mus musculus) PubMed

 653.

the phosphorylation pattern and activity of the kinase p90rsk,during in vitro and in vivo maturation of pig oocytes. (Mus musculus) PubMed

 654.

Platelet derived growth factor A and B (PDGF-A/PDGF-B) were up-regulated in model of obliterative bronchiolitis. (Mus musculus) PubMed

 655.

Arylesterase distribution in minipig skin in similar to that in human skin. (Mus musculus) PubMed

 656.

Demonstrate the presence of a human lactoferrin receptor homologue in pig, with mRNA and protein expression concomitantly regulated in the duodenum and inversely regulated in the jejunum. (Mus musculus) PubMed

 657.

Blockade of the thromboxane A2/prostaglandin H2 receptor provided a fast and potent platelet inhibitory effect in a porcine model of in-stent thrombosis. (Mus musculus) PubMed

 658.

the N(pro) protein targets interferon regulatory factor-3 (IRF-3) for degradation by proteasomes and thus prevents IRF-3 from activating transcription from the IFN-beta promoter. (Mus musculus) PubMed

 659.

Beneficial effect of nicorandil on endothelial junctions could be due to its effect on endothelin-1 (ET-1) via the activation of KATp channel. (Mus musculus) PubMed

 660.

mitocryptide-2 (MCT-2) and its human homolog hMCT-2 are cryptides that activate neutrophils[Mitocryptide-2] (Mus musculus) PubMed

 661.

Results discuss how constitutively bound factors such as NF1 and Oct1 may participate in the maintenance of tissue specificity of genes responsive to hormones through receptors such as the glucocorticoid receptor. [Nf1] (Mus musculus) PubMed

 662.

Hsp70 expression in the thoraces of flight-capable bees is probably flight-induced by oxidative and mechanical damage to flight muscle proteins rather than temperature.[HSP70] (Mus musculus) PubMed

 663.

Strains with mutations in either the prcA-prtP or the msp region showed altered expression of the other locus. (msp = major outer sheath protein) (Mus musculus) PubMed

 664.

The gene encoding the Treponema denticola factor H-like protein 1 (FHL-1) binding protein, FhbB, was recovered and characterized [FhbB] (Mus musculus) PubMed

 665.

Msp inhibits the polarized accumulation of activated Rac and PI3-kinase products upon exposure to formyl-methionyl-leucyl-phenylalanine (fMLP). [major outer sheath protein (Msp)] (Mus musculus) PubMed

 666.

These data suggest that major outer sheath protein (MSP) acts as an adhesin during the coaggregation process of T. denticola with P. gingivalis and F. nucleatum through its protein and carbohydrate moieties, respectively. [MSP] (Mus musculus) PubMed

 667.

In this study we demonstrated with a pull-down assay that purified full-length recombinant lipoprotein FhbB (lacking the leader peptide) binds exclusively to FH and not to FHL-1(factor H-like protein 1). [FhbB] (Mus musculus) PubMed

 668.

Results of our studies suggest that the C. jejuni NeuNAc synthase catalyses the condensation of the si face of PEP with the aldehyde sugar. [neuB1] (Mus musculus) PubMed

 669.

A Campylobacter jejuni two-component signal transduction system, designated dccR-dccS (diminished capacity to colonize; Cj1223c-Cj1222c), has been found to be important for in vivo colonization but dispensable for in vitro growth [dccR;dccS strain 81-176] (Mus musculus) PubMed

 670.

alternative model of evolution for FbpA homologs involving an early iron-binding ancestor instead of a requirement for a preexisting anion-binding ancestor. (ferric binding protein) (Mus musculus) PubMed

 671.

identification and characterization of a new DsbB-related disulfide oxidoreductase (DsbI) from C. jejuni [DsbI] (Mus musculus) PubMed

 672.

findings show the profound effect of a resistance-conferring point mutation in gyrA on the fitness of a foodborne pathogen in its natural host & suggest a reason for the rapid emergence of FQ-resistant Campylobacter on a worldwide scale [gyrA, strain S3B] (Mus musculus) PubMed

 673.

The frequence, chromosomal distribution and localization of tet(O) on plasmid and chromosomal DNA of C. jejuni strains isolated in Australia is reported. [tet(O) gene] (Mus musculus) PubMed

 674.

cloning, sequence analysis and expression of OXA-61, a novel molecular class D beta-lactamase [OXA-61] (Mus musculus) PubMed

 675.

Phenylalanine-arginine-leucine-serine residues (CadF AA 134-137) of the C. jejuni CadF protein possess fibronectin-binding activity. (Mus musculus) PubMed

 676.

DprA ortholog that functionally most closely resembles that of H. pylori and is involved in DNA transformation [DprA] (Mus musculus) PubMed

 677.

In this study, an unusual phase-variable mechanism controlling production of FlgR, the response regulator of the FlgSR two-component system required for transcription of sigma54-dependent flagellar genes, is identified. (Mus musculus) PubMed

 678.

the Cj0618 gene deletion mutant showed a caecal colonization defect in chick infection.[Cj0618] (Mus musculus) PubMed

 679.

The data suggest that DocA and Cjj0382 have characteristics of CCPs but likely perform different physiological functions for the bacterium in colonization that are not related to resisting oxidative stress. [docA and Cjj0382] (Mus musculus) PubMed

 680.

Data suggest that the FlgR receiver domain has the capacity for regulation in controlling the activation of the protein and FlgR lacks a DNA-binding motif and is not required for sigma(54)-dependent flagellar gene expression [FlgR] (Mus musculus) PubMed

 681.

CprRS influences expression of factors important for biofilm formation, colonization and stress tolerance. [CprR; CprS] (Mus musculus) PubMed

 682.

By using genetic approaches, we found that FlgSR activity is linked to and downstream of the flagellar export apparatus in a regulatory cascade that terminates in expression of sigma(54)-dependent flagellar genes.[FlgS & FlgR] (Mus musculus) PubMed

 683.

In summary, mutation of cj0596 alters the Campylobacter jejuni OMP profile and leads to changes in OMP-related phenotypes involved in Campylobacter jejuni pathogenesis.[cj0596 homolog] (Mus musculus) PubMed

 684.

The three-dimensional structure of H. pylori ACP and its structural characteristics were clarified using NMR and CD spectroscopy [Acyl carrier protein] (Mus musculus) PubMed

 685.

crystal structure of Spermidine Synthase [Spermidine Synthase] (Mus musculus) PubMed

 686.

interaction of HSP60 with TLR (toll-like receptors)in gastric epithelial cells contributes to development of gastic inflammation of H. pylori infection. [HSP60] (Mus musculus) PubMed

 687.

results demonstrate that periplasmic carbonic anhydrase is essential for survival of H. pylori in an acid environment studied in vitro [alpha-CA strain ATCC43504] (Mus musculus) PubMed

 688.

interacts with fibronectin and alters HeLa cell adhesion and cytoskeletal organization in vitro [VacA] (Mus musculus) PubMed

 689.

The vacuolating activity of VacA is due mainly to the free-soluble form rather than the outer membrane vesicle-associated form of VacA. (Mus musculus) PubMed

 690.

Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori [Hp-QAPRTase] (Mus musculus) PubMed

 691.

role of DsbI protein in Helicobacter pylori pathogenesis; demonstrated that a dsbI mutant impaired in disulfide bond formation revealed a greatly reduced ability to colonize mice gastric mucosa [DsbI] (Mus musculus) PubMed

 692.

The recombinant KatA has original antigenicity. [KatA] (Mus musculus) PubMed

 693.

Altogether, Ni-free and Ni-bound structures have allowed determination of the route for nickel within HpNikR and reveal the cooperativity between the tetramerization domain and the DNA-binding domain. [NikR protein] (Mus musculus) PubMed

 694.

We identify the gene hp0421 as encoding the enzyme cholesterol-alpha-glucosyltransferase responsible for cholesterol glucosylation [hp0421] (Mus musculus) PubMed

 695.

we analyzed the amino acid sequence of HrcA that predicted association of this protein to the inner membrane, which was experimentally verified. The functionality of the purified protein was then confirmed with an in vitro DNA-binding assay.[HrcA] (Mus musculus) PubMed

 696.

The prevalence of cytotoxin-associated gene A positivity was significantly higher in Behcet's disease compared to the controls [cagA] (Mus musculus) PubMed

 697.

hp0015 is associated with adhesion, and hp0015, hp0016, and hp0017 are associated with natural transformation. Hp0017 has been named as virB4/comB4. Therefore, hp0015 and hp0016 are named as comB2 and comB3, respectively.[virB4, comB2, comB3] (Mus musculus) PubMed

 698.

structure-function relationships of residues in the fifth transmembrane domain (TM5) of the Na+/H+ antiporter A (NhaA) from Helicobacter pylori [Na+/H+ antiporter] (Mus musculus) PubMed

 699.

These results indicate that perturbation of the E-cadherin/beta-catenin complex by H. pylori CagA plays an important role in the development of intestinal metaplasia. (Mus musculus) PubMed

 700.

results suggest that ERK and p38 MAPK signalling linked to the TLR2 recognition receptor in human monocytes may be an important pathway in H. pylori-HSP60-induced IL-8 secretion [HSP-60] (Mus musculus) PubMed

 701.

Helicobacter pylori formamidase AmiF has a cysteine-glutamate-lysine catalytic triad, as shown by crystallographic analysis (Mus musculus) PubMed

 702.

GatCAB is equally efficient in glutamine-dependent transamidation of Asp-tRNAAsn and Glu-tRNAGln [GatCAB] (Mus musculus) PubMed

 703.

The H.pylori neutrophil-activating protein is able to bind and condense DNA by a mechanism different from that described for E.coli Dps (neutrophil-activating protein). (Mus musculus) PubMed

 704.

Study identified Crk adapter proteins, Rac1 and H-Ras, but not RhoA or Cdc42 as crucial components of the CagA-induced phenotype. (Mus musculus) PubMed

 705.

High levels of diversity of activity of CagA H. pylori strains in gastric epithelial cells and its association with polymorphism in CagA gene. [CagA] (Mus musculus) PubMed

 706.

provides further evidence for a causal role of CagA+ H pylori infection in the immunopathogenesis of gastric cancer [CagA] (Mus musculus) PubMed

 707.

Present work provides useful information for understanding the D-Ala-D-Ala ligase of Helicobacter pylori. (Mus musculus) PubMed

 708.

Crystal structure of YbgC was determined and its enzymatic activity was characterized. (YbgC) (Mus musculus) PubMed

 709.

These data indicate that the assembly of functional oligomeric VacA complexes is dependent on specific sequences, including amino acids 346 and 347, within the p55 amino-terminal subdomain. [VacA] (Mus musculus) PubMed

 710.

the effect of VacA on the secretion of macrophages as an individual virulence determinant [VacA] (Mus musculus) PubMed

 711.

Hpn-like (Hpnl) protein, encoded by the hpnl gene in Helicobacter pylori and featuring a histidine-rich and two glutamine-rich motifs, can render nickel tolerance to H. pylori when the external nickel level reaches toxic limits.[hpnl] (Mus musculus) PubMed

 712.

cagT can stimulate SGC-7901 cells to express cytokine interleukin-8 and inhibit proliferation [cagT] (Mus musculus) PubMed

 713.

in unstable angina patients, immune response against CagA-positive H. pylori strains might be critical to coronary instability mediated by antigen mimicry between CagA antigen and a protein contained in coronary atherosclerotic plaques[CAGA]Review (Mus musculus) PubMed

 714.

Study shows a significant proatherogenic effect of H. pylori-secreted factor VacA on a range of vascular endothelial dysfunction markers. (Mus musculus) PubMed

 715.

Genotyping of vacA and cagA in H. pylori by a multiplex polymerase chain reaction assay for use in developing countries is reported.[vacA; cagA] (Mus musculus) PubMed

 716.

Protein dynamics and flexibility in the activated and inactivated state, respectively, was analysed by probing accessibility in (1)H/(2)H exchange experiments for the wild type and the mutant NhaA which is constitutively active independent of pH.[NhaA] (Mus musculus) PubMed

 717.

In China the prevalence of dupA gene was highest in duodenal ulcer and inversely related to gastric ulcer and gastric cancer. (Mus musculus) PubMed

 718.

ClpP and ClpA mutants display reduced macrophage and murine survival. [ClpA, ClpP] (Mus musculus) PubMed

 719.

inhibition of EGFR endocytosis occurs via a CagA-dependent activation of the non-receptor kinase c-Abl, which in turn phosphorylates the EGFR target site pY1173.[CagA in strain P1] (Mus musculus) PubMed

 720.

These data indicate that in some strains of H. pylori, the HopQ outer membrane protein can attenuate bacterial adherence to gastric epithelial cells.[HopQ] (Mus musculus) PubMed

 721.

The interactions between HPNikR and the target operator sequences of the genes directly regulated (ureA, NixA, NikR, Fur OPI, Fur OPII, Frpb4, FecA3, and exbB) were characterized.[NikR] (Mus musculus) PubMed

 722.

study reports a statistical link between the East Asian CagA EPIYA-ABD genotype and the development of gastric cancer [CagA] (Mus musculus) PubMed

 723.

the induction of autophagy by VacA may represent a host mechanism to limit toxin-induced cellular damage [VacA, strain 60190] (Mus musculus) PubMed

 724.

findings show that cagA gene is relevant to the expressions of antioxidant proteins of H pylori, which may be a novel mechanism involved in H pylori cagA pathogenesis[cagA] (Mus musculus) PubMed

 725.

Virulence factors like cagA and vacA enhance gastric mucosal inflammation & are associated with the development of peptic ulcer & gastric cancer. They induce proinflammatory cytokines. [vacA;cagA] Review. (Mus musculus) PubMed

 726.

the neutrophil-activating protein not only plays a role in driving Th1 inflammation but it is also able to inhibit Th2 responses in vitro and in vivo in allergic bronchial asthma, in humans and mice (neutrophil-activating protein; NAP) (Mus musculus) PubMed

 727.

Binding of H. pylori adhesins BabA and SabA to the whole range of salivary proteins was explored.[SabA] (Mus musculus) PubMed

 728.

A significant correlation between peptic ulceration and the presence of H. pylori isolates carrying cagE and cagA genes was demonstrated in Iranian patients. (cagE and cagA) (Mus musculus) PubMed

 729.

results indicate that CagA variants are linked with premalignant lesions in distinct populations and that epithelial responses to these strains are selective based upon locale [CagA] (Mus musculus) PubMed

 730.

FldA induction is independent of the Fur protein under iron starvation. [FldA, Fur] (Mus musculus) PubMed

 731.

Deletion of FlhB inhibits expression of both RpoN- and FliA- dependent reporter genes. (Mus musculus) PubMed

 732.

These studies thus show that the H. pylori CheV proteins each differently affect swimming behaviour. [CheV1, CheV2, CheV3] (Mus musculus) PubMed

 733.

The HugZ-haemin complex has been purified and crystallized and diffraction data sets have been collected to 1.8 A resolution.[HugZ] (Mus musculus) PubMed

 734.

The secreted Helicobacter cysteine-rich protein A causes adherence of human monocytes and differentiation into a macrophage-like phenotype (Mus musculus) PubMed

 735.

The structures of a truncated version of Tipalpha (TipalphaN34) in two crystal forms are presented here (Mus musculus) PubMed

 736.

Helicobacter pylori strains isolated from Mexican chronic gastritis patients are highly positive for vacA, cagA and babA2 virulence markers. [vacA, cagA, babA2] (Mus musculus) PubMed

 737.

The present study focuses on the metal-binding properties of HpUreE (Helicobacter pylori UreE) and its interaction with the related accessory protein HpUreG.[UreE, UreG] (Mus musculus) PubMed

 738.

CagA, vacA s1m1, and iceA1 genotypes are the predominant genotypes of H pylori isolated from the southeastern European pediatric population. [cagA, vacA, and iceA] (Mus musculus) PubMed

 739.

findings show that the biological half-life of CagA is about 200 min in gastric epithelial cells; CagA is a relatively short half-life protein whose stability may be modulated through complex formation with PAR1 [CagA] (Mus musculus) PubMed

 740.

Using in vitro infection assays, the authors showed that Helicobacter pylori CagA interacts with E-cadherin, p120-catenin, and c-Met. (Mus musculus) PubMed

 741.

These results indicated that the oligomeric status of HpHsp60s might have an important role in regulating host inflammation and thus help facilitate H. pylori persistent infection. (Hsp60) (Mus musculus) PubMed

 742.

A higher prevalence of more virulent cagA genotype was found in children compared to adults. [cagA] (Mus musculus) PubMed

 743.

All 126 isolates possessed cagA, with the majority encoding EPIYA-A (97.6%) and all encoding EPIYA-B. [cagA] (Mus musculus) PubMed

 744.

VacA activated NF-kappaB via classical but not alternative pathway. [VacA] (Mus musculus) PubMed

 745.

These results revealed that the C-terminal region of HPNAP is indispensable for human neutrophil stimulation and their further adhesion to endothelial cells - a step necessary to H. pylori inflammation.[ HPNAP] (Mus musculus) PubMed

 746.

Report distribution of Helicobacter pylori (strain not specified) cagA, cagE, oipA and vacA in different major ethnic groups in Tehran, Iran. (Mus musculus) PubMed

 747.

tolC is a critical virulence factor of F. tularensis [tolC] (Mus musculus) PubMed

 748.

The identification of the F. tularensis surface protein FsaP is reported, which, when expressed in nonadherent Escherichia coli, confers recombinant bacteria with the ability to bind to A549 cells. (Mus musculus) PubMed

 749.

The LpnA-deficient strain showed equivalent ability to promote secretion of chemokines by human monocyte-derived macrophages as its wild-type counterpart.[Tul4] (Mus musculus) PubMed

 750.

role in host cell adhesion, virulence, and fiber assembly. [pilT, pilF] (Mus musculus) PubMed

 751.

the IglC, IglD, and MglA proteins each directly or indirectly critically contribute to the virulence of F. tularensis LVS, including its intracellular replication, cytoplasmic escape, and inhibition of acidification of the phagosomes.[IglC, IglD, MglA] (Mus musculus) PubMed

 752.

the interaction between surface nucleolin and its bacterial ligand EF-Tu plays an important role in Francisella tularensis adhesion and entry process and may therefore facilitate invasion of host tissues [bacterial elongation factor Tu] (Mus musculus) PubMed

 753.

The IglA-IglB complex formation is clearly crucial for Francisella pathogenicity.[IglA & IglB] (Mus musculus) PubMed

 754.

F. tularensis subsp.holarctica strain LVS prevents neutrophil activation and intramacrophage killing via carA, carB, and pyrB genes, (small and large subunits of carbamoylphosphate synthase and aspartate carbamoyl transferase). [carA, carB, pyrB] (Mus musculus) PubMed

 755.

report validation of the predicted route (NaMN --> NMN --> NAD) in F. tularensis including mathematical modeling[nadE] (Mus musculus) PubMed

 756.

the cloning, expression, purification and crystallization methods for the class C acid phosphatases from F. tularensis and Pasteurella multocida are reported.[AcpC] (Mus musculus) PubMed

 757.

The authors have identified migR (FTL_1542), a gene that regulates expression of the iglABCD operon and is essential for bacterial growth in monocyte-derived macrophages and also contributes to the blockade of neutrophil NADPH oxidase activity.[migR] (Mus musculus) PubMed

 758.

The structures show that the core domain supplies the phosphoryl binding site, catalytic histidine (His17), and an aspartic acid residue (Asp261), while the cap domain contributes residues that enforce substrate preference.[ histidine acid phosphatase] (Mus musculus) PubMed

 759.

Two crystal forms of KDGK from Thermus thermophilus were obtained by vapour-diffusion and microbatch methods. [2-keto-3-deoxygluconate kinase] (Mus musculus) PubMed

 760.

ttMutS2 demonstrated the ability to bind double-stranded (ds) DNA, but, unlike ttMutS, ttMutS2 showed no specificity for mismatched duplexes [mutS2] (Mus musculus) PubMed

 761.

three-dimensional NMR solution structure of NusG from Thermus thermophilus, which shows 43% amino acid sequence similarity to the Escherichia coli NusG [NusG] (Mus musculus) PubMed

 762.

crystal structure of carboxypeptidase 1 [carboxypeptidase 1] (Mus musculus) PubMed

 763.

Thermus thermophilus putative periplasmic glutamate/glutamine-binding protein 1099 x-ray crystallographic structure [TT1099] (Mus musculus) PubMed

 764.

biochemical properties of the trehalose-6-phosphate synthase (otsA) and trehalose-6-phosphate phosphatase (otsB) in Thermus thermophilus RQ-1 [otsA and otsB] (Mus musculus) PubMed

 765.

structures revealed the elements that are responsible for the oligomerization modes. The distributions of the electrostatic potential on the solvent-accessible surfaces suggested putative active sites(Thermus thermophilus HB8, TT1887 and TT1465) (Mus musculus) PubMed

 766.

TT1383 is a novel dNTP triphosphohydrolase stimulated by dATP and dTTP (Mus musculus) PubMed

 767.

crystal structure of RraA[RraA] (Mus musculus) PubMed

 768.

The N-terminal helix was concluded to play no significant role in the specific binding of the S15 protein to its target on 16S rRNA[ribosomal protein S15] (Mus musculus) PubMed

 769.

A thermostable beta-ketothiolase from T. thermophilus was isolated and characterized. (Mus musculus) PubMed

 770.

crystal structure of the P-protein of the glycine cleavage system from Thermus thermophilus HB8 has been determined; first reported crystal structure of a P-protein [P-protein] (Mus musculus) PubMed

 771.

crystal structures of two mutants of Thermus thermophilus EF-G, G16V and T84A, which exhibit Fusidic acid hypersensitivity and resistance in vitro [EG-F] (Mus musculus) PubMed

 772.

Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes [ribosomal proteins L12 & L10] (Mus musculus) PubMed

 773.

The role of the individual enzyme components on protein maturation and activation of nitrate reductase in T. thermophilus is reported. [nar] (Mus musculus) PubMed

 774.

The post-transfer-editing and product complexes of Thermus thermophilus LeuRS (LeuRSTT) with tRNA(Leu) at 2.9- to 3.3-A resolution was described. (LeuRSTT),(tRNA-Leu). (Mus musculus) PubMed

 775.

The activity of the separately expressed and purified nucleotide binding domains of ClpB from T. thermophilus is reported.[clpB] (Mus musculus) PubMed

 776.

structure and function of the dimanganese catalase are discussed[dimanganese catalase ] (Mus musculus) PubMed

 777.

crystal structure of subunit F of vacuole-type ATPase/synthase was determined to of 2.2 A resolution; the subunit F exhibits two conformations, a 'retracted' form in the absence and an 'extended' form in the presence of ATP [V-ATPASE subunit F] (Mus musculus) PubMed

 778.

Transition from the GTP-bound to the GDP-bound state involves substantial conformational changes of IF2 and of the entire ribosome. (Mus musculus) PubMed

 779.

Using neutron spin-echo spectroscopy (NSE), normal mode analysis, and a statistical-mechanical framework, we reveal overdamped, coupled domain motion within DNA polymerase I from Thermus aquaticus [Taq polymerase] (Mus musculus) PubMed

 780.

six of the 12 ancestral mutants of 3-isopropylmalate dehydrogenase tested showed thermal stability higher than that of the original enzyme[3-isopropylmalate dehydrogenase] (Mus musculus) PubMed

 781.

comparison of the protein-RNA interactions in the L1-mRNA and L1-rRNA complexes identified amino acid residues of L1 crucial for recognition of its specific targets on the both RNAs [ribosomal protein L1 ] (Mus musculus) PubMed

 782.

A study of the Thermus thermophilus chorismate mutase is described by using quantum mechanics (self-consistent-charge density-functional tight binding)/molecular mechanics, umbrella sampling, and the weighted histogram analysis method [chorismate mutase] (Mus musculus) PubMed

 783.

X-ray crystallographic study of the L-fuculose-1-phosphate aldolase (FucA) from Thermus thermophilus HB8 [FucA] (Mus musculus) PubMed

 784.

Results describe the structure, function, possible mechanism of action and regulation of Gfh1. (Mus musculus) PubMed

 785.

rhodanese homologue TTHA0 is crystallized and its molecular structure exmined. (rhodanese homologue TTHA0613 (Mus musculus) PubMed

 786.

The crystal structure of EF-Tu x pulvomycin in complex with the guanylyl imino diphosphate at 1.4 A resolution reveals an antibiotic binding site extending from the domain 1-3 interface to domain 2, overlapping the domain 1-2-3 junction.(EF-Tu) (Mus musculus) PubMed

 787.

versatile enzyme activities of TthNfo play an important role in counteracting DNA base damage in vivo[endonuclease IV] (Mus musculus) PubMed

 788.

Two mutants, containing multiple mutations, were constructed and show greater thermal stabilities than the wild-type and single-point mutant 3-isopropylmalate dehydrogenase (IPMDHs) do. [3-Isopropylmalate dehydrogenase] (Mus musculus) PubMed

 789.

Purified/characterized sulfite oxidase from Thermus thermophilus. (Mus musculus) PubMed

 790.

Temperature dependence of the structure of the substrate and active site of the chorismate mutase E x S complex was studied. (Mus musculus) PubMed

 791.

Report presents the crystal structure of the N-terminal domain of the Thermus thermophilus RNA helicase Hera in complex with adenosine monophosphate (AMP). [RNA helicase Hera] (Mus musculus) PubMed

 792.

Data describe the cloning, over-expression, characterization of cognate ligands, and determination of the X-ray crystal structure of a glucose binding protein from Thermus thermophilus [TtGBP]. (Mus musculus) PubMed

 793.

We report the presence of Mlc in a thermophilic bacterium; Mlc is the first gene within an operon encoding an ABC transporter for glucose and mannose, including a glucose/mannose-binding protein and two permeases [Mlc] (Mus musculus) PubMed

 794.

protein S1 binds in the region of the neck of the 30S ribosomal subunit inducing a conformational change of its structure[Ribosomal protein S1] (Mus musculus) PubMed

 795.

2.1 A X-ray structure of FtsY from T. aquaticus bound to GDP [FtsY] (Mus musculus) PubMed

 796.

In purified GcpE enzyme, a new transient iron-sulfur-based signal is detected in electron paramagnetic resonance spectroscopy. (Mus musculus) PubMed

 797.

the conserved helix 3 of the M domain is specifically required for the DnaK-dependent shuffling of aggregated proteins, but not of soluble denatured substrates, to the pore entrance of the ClpB translocation channel. (ClpB) (Mus musculus) PubMed

 798.

ClpB captures substrates on the upper surface of the AAA-1 ring before threading them through the ClpB hexamer in an ATP hydrolysis-driven step. (ClpB) (Mus musculus) PubMed

 799.

The crystal structure of T. thermophilus RF2 is similar to the compact structures of E. coli RF2 (RF2). (Mus musculus) PubMed

 800.

A network of interaction with the ribosome establishes the active GTP conformation of EF-G and thus facilitates GTP hydrolysis and tRNA translocation.[EF-G] (Mus musculus) PubMed

 801.

The structure of protein SI of Thermus thermophilus (M = 61 kDa) in solution at low and moderate ionic strengths (0 M and 100 mM NaCl, respectively) has been studied by small-angle X-ray and neutron scattering. (Mus musculus) PubMed

 802.

description of the crystal structure of the Thermus thermophilus ribosome recycling factor (RRF) bound to a 70S ribosomal complex containing a stop codon in the A site, a transfer RNA anticodon stem-loop in the P site and tRNA(fMet) in the E site [RRF] (Mus musculus) PubMed

 803.

the crystal structures of the full-length Thermus thermophilus MgtE at 3.5 A resolution, and of the cytosolic domain in the presence and absence of Mg2+ at 2.3 A and 3.9 A resolutions, respectively [MgtE] (Mus musculus) PubMed

 804.

dodecins can act as bifunctional cofactor storage proteins that sequester catalytic cofactors in prokaryotes very efficiently in an aggregated and unreactive state[ dodecin ] (Mus musculus) PubMed

 805.

Indicate formation of ribonucleoprotein complex composed of aspartyl-tRNA synthetase (DRS2)/tRNA-dependent amidotransferase (AdT)/aspartyl-tRNA involved in asparagine biosynthesis. (Mus musculus) PubMed

 806.

is a successful application of this approach to the integral membrane protein Thermus thermophilus cytochrome ba(3) oxidase[cytochrome ba3] (Mus musculus) PubMed

 807.

CutA1 proteins from Thermus thermophilus (TtCutA1) and Oryza sativa (OsCutA1) and Pyrococcus horikoshii (PhCutA1)were examined, in order to elucidate the stabilization mechanism of PhCutA1.[CutA1] (Mus musculus) PubMed

 808.

confirmed the tetrameric oligomerization state of TrmI[TrmI] (Mus musculus) PubMed

 809.

ClpB forms a very dynamic complex, reshuffling subunits on a timescale comparable to steady-state ATP hydrolysis.(ClpB) (Mus musculus) PubMed

 810.

domain structure of IF-2 [IF-2] (Mus musculus) PubMed

 811.

computer simulations of the peptidyl transfer reaction in the T. thermophilus ribosome to address the role of L27 [rpmA] (Mus musculus) PubMed

 812.

1.9 A resolution structure of Thermus thermophilus proline dehydrogenase inactivated by the mechanism-based inhibitor N-propargylglycine [proline dehydrogenase ] (Mus musculus) PubMed

 813.

analysis using molecular dynamics simulations to explain higher fidelity compared to the wild type enzyme [Thermus aquaticus DNA polymerase I] (Mus musculus) PubMed

 814.

A recombinant futalosine hydrolase (TTHA0556) of T. thermophilus, which participates in the second step of the pathway and catalyzes the reaction releasing hypoxanthine from futalosine, was prepared and used in functional analyses.[TTHA0556] (Mus musculus) PubMed

 815.

study reports the crystal structure of elongation factor P (EF-P) bound to the 70S ribosome along with the initiator transfer RNA N-formyl-methionyl-tRNA(i) (fMet-tRNA(i)(fMet)) & a short piece of mRNA at a resolution of 3.5 angstroms [EF-P] (Mus musculus) PubMed

 816.

determined two crystal structures of C-terminal fragments of heat resistant RNA-dependent ATPase from Thermus thermophilus.[DEAD-box RNA Helicase] (Mus musculus) PubMed

 817.

Crystal structures of ternary complexes of Thermus thermophilus Ago catalytic mutants with 5'-phosphorylated 21-nucleotide guide DNA and complementary target RNAs of 12, 15 and 19 nucleotides in length [Ago] (Mus musculus) PubMed

 818.

AvrXv4 functions like a SUMO protease during Xanthomonas-plant interactions (AvrXv4). (Mus musculus) PubMed

 819.

Data suggest that HpaB promotes the secretion of a large set of effector proteins and prevents the delivery of non-effectors into the plant cell [HpaB] (Mus musculus) PubMed

 820.

plays an important role in, but is not solely responsible for, both the adaptive and menadione-induced cross-protective responses to H2O2 killing in X. campestris. [katA] (Mus musculus) PubMed

 821.

Crystal structure of N-acetylornithine transcarbamylase (Mus musculus) PubMed

 822.

Transcription initiation site for virulence factor engA was determined. (Mus musculus) PubMed

 823.

expression of both katA(catalase) and ahpC (alkyl hydroperoxide reductase) is controlled by the global peroxide sensor and transcriptional activator, OxyR [KatA, AphC, OxyR] (Mus musculus) PubMed

 824.

X-ray analysis of XC229, a conserved hypothetical protein from Xanthomonas campestris (Mus musculus) PubMed

 825.

X-ray analysis of XC5357 from Xanthomonas campestris (Mus musculus) PubMed

 826.

X-ray characterization of a conserved hypothetical protein XC6422 from Xanthomonas campestris (Mus musculus) PubMed

 827.

X-ray crystallographic analysis of XC847, a 3'-5' oligoribonuclease from Xanthomonas campestris [XC847] (Mus musculus) PubMed

 828.

The structure of a novel acetylcitrulline deacetylase from Xanthomonas campestris has been solved by multiple-wavelength anomalous dispersion (MAD) using crystals grown from selenomethionine-substituted protein and refined at 1.75 A resolution. (argE) (Mus musculus) PubMed

 829.

the determined structure of XC6422 shows that it belongs to the superfamily of serine alpha/beta-hydrolases, with an active site that is fully accessible to solvent owing to the absence of a lid domain [XC6422] (Mus musculus) PubMed

 830.

RpfC modulates two different functions (virulence factor synthesis and DSF synthesis) by utilization of a conserved phosphorelay system and a novel domain-specific protein-protein interaction mechanism, respectively[RpfC] (Mus musculus) PubMed

 831.

XC5357 ia a putative tetracenomycin polyketide synthesis protein adopting a cupin subfamily structure (XC5357) (Mus musculus) PubMed

 832.

The crystal structure of XC847 from Xanthomonas campestris (Mus musculus) PubMed

 833.

A novel N-acetylglutamate synthase/kinase bifunctional enzyme of arginine biosynthesis that was homologous to vertebrate N-acetylglutamate synthases was identified in Xanthomonas campestris.[N-acetylglutamate synthase/kinase] (Mus musculus) PubMed

 834.

The functional promiscuity discovered for fuconate dehydratase highlights possible structural mechanisms for evolution of function in the enolase superfamily. [fuconate dehydratase] (Mus musculus) PubMed

 835.

enzyme from X. campestris could become a good model for mammalian N-acetylglutamate synthase-kinase in structural, biochemical and biophysical studies[N-acetylglutamate synthase-kinase ] (Mus musculus) PubMed

 836.

In the present study, the presence of poly ADP-ribose polymerase (PARP)-like activity associated with caspase-3-like protein of Xanthomonas campestris pv. glycines is reported.[caspase-3-like protein] (Mus musculus) PubMed

 837.

A single amino acid substitution is sufficient to swap the substrate specificities of N-acetyl-L-ornithine transcarbamylase (N-acetyl-L-ornithine transcarbamylase). (Mus musculus) PubMed

 838.

R286A mutation caused XpsE lose the ability to associate with the cytoplasmic membrane via XpsL(N); as a consequence, ATP hydrolysis by XpsE was uncoupled from protein secretion. (XpsE) (Mus musculus) PubMed

 839.

The susceptibility of the mutant to unrelated chemicals indicated a general role for OmlA in maintaining membrane integrity.[OmlA in Xanthomonas campestris pv. phaseoli] (Mus musculus) PubMed

 840.

The structures of reduced and organic hydroperoxides-oxidized OhrR, visualizing the structural mechanism of OHP induction. (Mus musculus) PubMed

 841.

Our findings extend previous work on Clp and RpfF regulation to show that they both influence the expression of pehA in Xcc.[PehA, Clp and RpfF in strain Xc17] (Mus musculus) PubMed

 842.

The structure of an intact OGT homolog and kinetic analysis of human OGT variants reveal a contiguous superhelical groove that directs substrates to the active site.[OGT] (Mus musculus) PubMed

 843.

In addition to acting as a repressor of putative Zn(2+)-uptake systems, the Zur of the bacterial phytopathogen Xanthomonas campestris acts as an activator of a Zn(2+) efflux pump (Zur). (Mus musculus) PubMed

 844.

FlgD comprises two individual domains, a flexible N-terminal domain that cannot be detected in the current study and a stable C-terminal domain that forms a stable dimer[flagellar hook-capping protein ] (Mus musculus) PubMed

 845.

The tertiary structures of the apo- and GTP-bound forms of uridylate kinase (UMPK) from the gram-negative plant pathogen Xanthomonas campestris, were determined.[UMPK] (Mus musculus) PubMed

 846.

HrcN from the plant pathogenic bacterium Xanthomonas campestris pathovar vesicatoria hydrolyzes ATP and is essential for T3S and bactieral pathogenicity. [HrcN] (Mus musculus) PubMed

 847.

Virulence activities of the effector proteins AvrBs1, AvrBs3 and AvrBs4 were uncovered using Agrobacterium-mediated transient expression of the corresponding genes in Nicotiana benthamiana, followed by microscopic analyses.[AvrBs1, AvrBs3, AvrBs4] (Mus musculus) PubMed

 848.

XopJ has a role in the inhibition of cell wall-based defense responses. (Mus musculus) PubMed

 849.

The crystal structure of XcPqqD was found to adopt a dimer of novel saddle-like fold that revealed considerable differences to the structure predicted de novo and carried out in the absence of suitable template.[PqqD] (Mus musculus) PubMed

 850.

XcBCP carries out its oxidoreduction activity through the alternate opening and closing of the substrate entry channel and the disulfide-bond pocket.[BCP] (Mus musculus) PubMed

 851.

X-ray structures of Neisseria meningitidis and Xanthomonas campestris MsrB have been determined.[MsrB] (Mus musculus) PubMed

 852.

described mutant forms of DctD that activated transcription efficiently from a dctA'-'lacZ reporter gene that possessed the upstream activation sequences (UAS), but not from a reporter gene that lacked the UAS. [DctD] (Mus musculus) PubMed

 853.

description of three distinct DNA sequence elements of the ExpG binding sites and their contribution to the specific binding process [ExpG strain2011] (Mus musculus) PubMed

 854.

dctA deletion mutants that contain the mutant dctA alleles on a plasmid can proceed further in symbiotic development than null mutants of dctA. (dctA) (Mus musculus) PubMed

 855.

findings supported the conclusion that RirA is the mediator of iron-responsive transcriptional repression of the two transcripts encoding the rhizobactin 1021 biosynthesis and transport genes [RirA] (Mus musculus) PubMed

 856.

molecular cloning and biochemical characterization including substrate specificity, kinetcs and reaction conditions of L-N-carbamoylase [L-N-carbamoylase] (Mus musculus) PubMed

 857.

Molecular model of the DNA-binding domain of FixJ that binds to the fixK promoter (fixj and fixk). (Mus musculus) PubMed

 858.

oxygen dramatically inhibited the reaction of the RmFixL-RmFixJ complex with ATP but affected neither ATP binding nor RmFixL-RmFixJ complex formation [FixL, FixJ] (Mus musculus) PubMed

 859.

The thermodynamic binding parameters of hydantoin racemase were studied (hydantoin racemase). (Mus musculus) PubMed

 860.

The expression of the nolR gene in Sinorhizobium meliloti AK631 was investigated in relation to stage of growth, availability of nutrients, and different environmental stimuli using the nolR::lacZ fusion report system. (Mus musculus) PubMed

 861.

bioinformatic, genetic, physiological, biochemical, and structural proof for reassignment of MotD, a protein previously thought to function as a cytoplasmic motility protein as a hook length regulator, FliK [MotD,FliK] (Mus musculus) PubMed

 862.

GroEL/GroES production alone cannot explain the requirements for RpoH1 and RpoH2 in S. meliloti. (Mus musculus) PubMed

 863.

The major role of BetS is as an emergency system involved in the rapid uptake of betaines in isolated and in planta osmotically stressed bacteroids of S. meliloti. (Mus musculus) PubMed

 864.

results suggest that ExpR may repress the expression of motC operon in a low cell density, but this repression can be deprived in a higher cell density [motC; ExpR] (Mus musculus) PubMed

 865.

The TolC protein of S. meliloti is assumed to be involved in the excretion of proteins ExsH and ExpE1. (Mus musculus) PubMed

 866.

The importance of thioredoxin in melanin production in bacteria, through the regulation of laccase or tyrosinase activities, or both, by the redox state of structural or catalytic SH groups, is discussed. [trxL] (Mus musculus) PubMed

 867.

NifA plays a regulatory role in multiple cellular processes in S. meliloti. [NifA] (Mus musculus) PubMed

 868.

The authors propose that the distinct CheY2 and CheY2-P surfaces interact with two overlapping sites in the P2 domain that selectively bind either CheY2 or CheY2-P, depending on whether CheA is active or inactive.[CheY2 & CheA in strain RU 13/281] (Mus musculus) PubMed

 869.

signalling through the FeuP/FeuQ pathway is responsive to extracellular osmotic conditions, with low osmolarity stimulating ndvA expression.[FeuP, FeuQ in strain SU47] (Mus musculus) PubMed

 870.

crystal analysis of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states (Mus musculus) PubMed

 871.

The nesR mutant was deficient in competing with the wild-type strain for plant nodulation.[nesR in strain Rm8530] (Mus musculus) PubMed

 872.

An ABC transporter plays a role in potassium transport regulation and alkaline stress.[ABC transporter] (Mus musculus) PubMed

 873.

The levels of lipids containing C16 fatty acids were decreased in plsC mutant. [plsC] (Mus musculus) PubMed

 874.

the crystal structure of ChoX in an unusual, ligand-free conformation that represents a semi-closed form of ChoX. [ChoX] (Mus musculus) PubMed

 875.

Rhizobium sp. strain NGR234 possesses a functional type three secretion system through which a number of proteins, called nodulation outer proteins (Nops), are delivered to the outside of the cell. (NopB) (Mus musculus) PubMed

 876.

Mutation of nopP leads to a dramatic reduction in nodule numbers on F. congesta and T. vogelii. (Mus musculus) PubMed

 877.

biochemical assays show here that NopA, NopB and NopX proteins interact directly with one another.[NopB & NopX] (Mus musculus) PubMed

 878.

DNase I footprinting revealed that TtsI occupied not only the tts box consensus sequence, but also upstream and downstream regions in a concentration-dependent manner.[TtsI] (Mus musculus) PubMed

 879.

NopJ and NopM are secreted by the type III secretion system. NopM can stimulate nodulation. [NopJ; NopM] (Mus musculus) PubMed

 880.

The UPase is a trimer of 43 kD subunits and has a maximal activity at a pH value of 7.8 and 50 degrees C. [Upase] (Mus musculus) PubMed

 881.

We confirmed that DspA/E acts as a major cell-death inducer during disease and HR, because the dspA/E mutant is severely impaired in its ability to induce electrolyte leakage in apple and tobacco leaves [DspA/E] (Mus musculus) PubMed

 882.

AvrRpt2EA acts as a virulence factor on immature pear fruits. (Mus musculus) PubMed

 883.

A major Erwinia amylovora outer-membrane protein (Omp-EA) and the gene encoding for this protein (omp-EA) were isolated and characterized. [Omp-EA] (Mus musculus) PubMed

 884.

We sequenced the putative autoinducer-2 (AI-2) synthase gene luxS from E. amylovora (Mus musculus) PubMed

 885.

Type three-secreted proteins DspA/E and HrpN induce cell death, activation of defense pathways, and ROS accumulation in Arabidopsis. [DspA/E and HrpN] (Mus musculus) PubMed

 886.

Inactivation of luxS impaired motility, extracellular polysaccharide (EPS) production, and tolerance for hydrogen peroxide, and reduced virulence on pear leaves. (Mus musculus) PubMed

 887.

Results suggests that the N-terminal and C-terminal halves of HrpN mediate cell-free elicitor activity and avirulence activity, respectively: [HrpN] (Mus musculus) PubMed

 888.

The waaL mutant showed reduced in virulence, a decrease in twitching motility, and increase sensitive to polymyxin B. [waaL] (Mus musculus) PubMed

 889.

2.0 A resolution crystal structure of the complex between the toxic domain of Colicin D and its immunity protein ImmD (Colicin D and ImmD) (Mus musculus) PubMed

 890.

resonance assignment of a 'donor-strand complemented' AfaE from Escherichia coli [AfaE or Afa-3] (Mus musculus) PubMed

 891.

CNF1 is a candidate virulence factor in E coli infections in ferrets [CNF1] (Mus musculus) PubMed

 892.

Analysis of the pH dependence of enzyme stability provides evidence that stable penicillin acylase conformation is maintained by salt bridges [penicillin acylase] (Mus musculus) PubMed

 893.

The saa gene is commonly associated with bovine eae-negative verotoxin-producing Escherichia coli (VTEC) strains but not with ovine or caprine VTEC strains. [saa] (Mus musculus) PubMed

 894.

EspG modulates enteropathogen's host cytoskeleton function involving transient microtubule destruction and actin polymerization [EspG] (Mus musculus) PubMed

 895.

Data show that expression of TetD activates transcription of a subset of the SoxS/MarA/Rob regulon genes and confers resistance to redox-cycling compounds and antibiotics [TetD]. (Mus musculus) PubMed

 896.

An exxmination of crystal structure and substrate specificity of this enzyme (isoaspartyl aminoptidase0 (Mus musculus) PubMed

 897.

ParG protein is shown to be a transcriptional repressor of the parFG genes. (ParG protein) (Mus musculus) PubMed

 898.

The structure of isoenzyme B (CysM) from Escherichia coli was established in a hexagonal crystal form at 2.7 A resolution. (CysM) (Mus musculus) PubMed

 899.

the TolB box sequence in ColE9 is actually larger than the pentapeptide and extends from residues 34 to 46[COLE9] (Mus musculus) PubMed

 900.

intrinsic differences between Tir from enterohemorrhagic and enteropathogenic strains of E coli were determined [Tir] (Mus musculus) PubMed

 901.

The role of the afaE and afaD genes in the mortality of pregnant rats from intrauterine infection with E. coli is reported.[afaE; afaD] (Mus musculus) PubMed

 902.

Results describe the crystal structure of the complex between E. coli RF1 and PrmC bound to the methyl donor product AdoHCy [RF1]. (Mus musculus) PubMed

 903.

biochemical analysis of binding of cytochrome bo3 from Escherichia coli (Mus musculus) PubMed

 904.

TolC and VceC are interchangeable for the functioning of the AcrAB and VceAB pumps. (VceC) (Mus musculus) PubMed

 905.

Recomsbinant F1F0 ATP synthasewas blocked in ATP hydrolysis activity, and this activity was stimulated by the detergent lauryldimethylamine oxide. (F1F0-ATP synthase) (Mus musculus) PubMed

 906.

Phosphorylation and dephosphorylation of poly(A) polymerase I (PAP I) effects the activity of the enzyme. (Mus musculus) PubMed

 907.

Study reports that EPEC strain B171 produces a functional Cif and that delivery of purified Cif into HeLa cells induces cell cycle arrest and actin stress fibres, implying that Cif is necessary and sufficient for these effects. [Cif protein] (Mus musculus) PubMed

 908.

Our results indicate that BarA-UvrY regulates virulence properties in Avian Pathogenic E. coli (APEC) [BARA, UvrY] (Mus musculus) PubMed

 909.

fine-tuning of the CRP activity may be critical for bacterial viability and adaptability to changing osmotic conditions [crp] (Mus musculus) PubMed

 910.

Results identify the 16-residue TolB binding epitope in the natively disordered T-domain of the nuclease colicin E9 (ColE9) and present the crystal structure of the complex [ColE9]. (Mus musculus) PubMed

 911.

Isolates with LEE + HPI gene were more frequently detected in diarrheic swine than in edematous swine and edematous/diarrheic swine.[IEE] (Mus musculus) PubMed

 912.

The presence of the tetracycline resistance determinant tet(M) in human clinical isolates of Escherichia coli is described for the first time in this report [tet(M)] (Mus musculus) PubMed

 913.

multiple genes associated with biofilm formation are regulated by aggR.[AggR] (Mus musculus) PubMed

 914.

Homologous AroQ chorismate mutases from the thermophile Methanococcus jannaschii & the mesophile Escherichia coli were compared as to their capacity to accommodate extensive mutation. There were 10% less functional variants in the E coli AroQ. (Mus musculus) PubMed

 915.

Stimulates ATP hydrolysis by ParF approximately 30-fold. The mobile tails of ParG are crucial for this enhancement; arginine R19 within the tail is absolutely required. (ParG) (Mus musculus) PubMed

 916.

data suggest that Hbp can fold in the periplasm but must retain a certain degree of flexibility and/or modest width to allow translocation across the outer membrane [Hbp] (Mus musculus) PubMed

 917.

The toxicity of EHEC-Hly to microvascular endothelial cells plausibly contributes to the virulence of the stx-negative E. coli O26 strains and to the pathogenesis of HUS. [Hly] (Mus musculus) PubMed

 918.

The EAEC strain 60A imp operon differs structurally from previously described homologs [impB, strain 60A] (Mus musculus) PubMed

 919.

we observed that MCP-1, and IL-8 to a lower extent, is produced in urine at higher concentrations in UTIs caused by UPECs carrying alpha-hly/cnf1 [cnf1] (Mus musculus) PubMed

 920.

Rabbit-specific enteropathogenic Escherichia coli plasmid-encoded autotransporter adhesin. (RpeA) (Mus musculus) PubMed

 921.

Selection for F18(+)E. coli resistant pigs might be an attractive approach to prevent pigs from F18(+)E. coli infections, unlike to what has previously been postulated. (Mus musculus) PubMed

 922.

computational analysis of the electrostatic properties of Lpp-56 (Braun's E. coli outer membrane lipoprotein (Lpp-56)) combining molecular dynamics simulations and continuum pK calculations (Mus musculus) PubMed

 923.

All four components of the yej locus are required for microcin sensitivity in E. coli.[Yej] (Mus musculus) PubMed

 924.

These results show that the DsbA is required for stable expression of outer membrane secretin EscC. [DsbA, EscC in strain 2348/69] (Mus musculus) PubMed

 925.

the N-terminal third of mature AIDA-I is involved in binding of this protein to cultured epithelial cells.[Aida-I] (Mus musculus) PubMed

 926.

A 3-dimensional map of melibiose permease was calculated from data obtained by electron crystallography. melB. (Mus musculus) PubMed

 927.

Enteropathogenic Escherichia coli O125:H6 lacks the ability to utilize either Nck or TccP/TccP2 and hence triggers actin polymerization in vitro only inefficiently.[TccP; TccP2] (Mus musculus) PubMed

 928.

Here we demonstrate that NleA compromises the Sec23/24 complex, a component of the mammalian COPII protein coat that shapes intracellular protein transport vesicles, by directly binding Sec24. [NleA] (Mus musculus) PubMed

 929.

SitABCD, MntH, and FeoB could potentially promote bacterial survival during infection by facilitating the transport of these trace metals and by countering oxidative stress during infection of the host. [SitA, B, C & D, MntH, FeoB in strain 7122] (Mus musculus) PubMed

 930.

mutagenesis study on intimin-binding domain of EPEC TIR & how mutations affect TIR-intimin association; a three-residue TIR hot spot is identified that mediates interaction; mutants altering beta-hairpin structure of TIR diminish binding affinity [TIR] (Mus musculus) PubMed

 931.

the results suggest that PapB and FocB can form heterodimers and that these complexes can repress expression of the foc operon.[PapB and FocB in strain J96] (Mus musculus) PubMed

 932.

Binding kinetics, mutational analysis and spectroscopic examination of CEA dimers suggest that Dr adhesins can dissociate CEA dimers prior to the binding of monomeric forms.[Dr adhesin] (Mus musculus) PubMed

 933.

The superb activity of the 8-oxoguanine glycosylases Fpg, hOGG1, and Ntg1 toward removal of FapyG and FapyA in vitro suggests that these enzymes may act upon these oxidized lesions in vivo.(Fpg) (Mus musculus) PubMed

 934.

Hek-mediated adherence is dependent on binding to glycosoaminoglycan. The ability to hemagglutinate, autoaggregate, adhere, and invade is contingent on a putative 25-amino-acid loop that is exposed to the outside of the bacterial cells. (Mus musculus) PubMed

 935.

These results suggest that TolC promotes the aggregation and adhesion of EAEC 042 by secreting an assumed humoral factor.[TolC in strain EAEC 042] (Mus musculus) PubMed

 936.

In the strain of Escherichia coli K1, data suggest the presence of two domains in the molecular structure of IbeA, with differential unfolding stabilities [IbeA] (Mus musculus) PubMed

 937.

The paper demonstrates a direct link between FyuA and biofilm formation in iron-poor environments. [FyuA] (Mus musculus) PubMed

 938.

Inserting a Phe near C46 in AhpC makes it inactive as a peroxidase. Some point mutants confer exhibit an enhanced reductase activity toward mixed disulfides between glutathione and glutaredoxin. [AhpC] (Mus musculus) PubMed

 939.

Data demonstrate that the conserved 'amphiphilic' feature of HdeA is essential for exhibiting chaperone-like activity under extremely low pH conditions. (Mus musculus) PubMed

 940.

the pattern of suppression suggests that two distinct sites on FliG interact with FliM, perhaps with two FliM molecules in a dimer per molecule of FliG.[FliM and FliG in strain HCB1] (Mus musculus) PubMed

 941.

the rpoS tnaB double mutant exhibited decreased adherence.[rpoS and tnaB in strain AIEC O83:H1] (Mus musculus) PubMed

 942.

GrlA upregulates the expression of LEE through binding of the LEE1 promoter, which in turn increases the level of LEE-encoded regulator allowing it to function as a downstream activator. [GrlA, Lee] (Mus musculus) PubMed

 943.

Without l-rhamnose, RhaS does not effectively bind DNA while RhaR does not effectively contact RNAP. Upon l-rhamnose binding, both proteins undergo structural changes that enable transcription activation.[RhaS, RhaR in strain SME3000] (Mus musculus) PubMed

 944.

The linkage between class 1 integrans, the dfrA12-orfF-aadA2 cassette array, and sul3 in multidrug resistant E. coli, is reported.[sul3] (Mus musculus) PubMed

 945.

findings demonstrate for that immunity release from enzymatic colicins occurs immediately after reduction of the disulfide bond of ColE9s-s leading to unfolding of the helical hairpin [ColE9] (Mus musculus) PubMed

 946.

From these data, we speculate that Hly hemolysin (HlyA) and cytotoxic necrotizing factor type 1 (CNF1), may be largely responsible for the signs and symptoms of cystitis in humans infected with toxigenic UPEC. [HlyA, CNF1] (Mus musculus) PubMed

 947.

Results describe mapping studies of the epitopes of three NhaA-specific conformational monoclonal antibodies, two of which drastically inhibit the antiporter. (Mus musculus) PubMed

 948.

Results describe the crystal structure of QOR2, a new type of NADPH-dependent quinone oxidoreductase from Escherichia coli [QOR2]. (Mus musculus) PubMed

 949.

Results present a structural characterisation of a conformational state populated at low pH by the N-terminal domain of Escherichia coli HypF [HypN-F]. (Mus musculus) PubMed

 950.

[strain MC4100, genes IbpA and IbpB] IbpA/B protect Escherichia coli cells from oxidative damage caused by copper (Mus musculus) PubMed

 951.

[strain YU423, glucose dehydrogenase] (Mus musculus) PubMed

 952.

the first report of aac (6')-Ib-cr gene in E. coli isolates from food-producing animals [(6')-Ib-cr] (Mus musculus) PubMed

 953.

the emergence of CTX-M-1-producing E. coli in western Austria may be attributed to multiple independent events [CTX-M-1] (Mus musculus) PubMed

 954.

Our findings suggest that one function of chaperonins may involve trapping unfolded proteins and subsequently exposing them to a microenvironment in which the hydrophobic effect, a crucial thermodynamic driving force for folding, is enhanced. [GroEL] (Mus musculus) PubMed

 955.

EspF(U) activates N-Wiskott-Aldrich syndrome protein by competitively disrupting the autoinhibited state [E.Coli O157:H7 strain not specified, EspF(U)] (Mus musculus) PubMed

 956.

EspF(U) forms an amphipathic helix that binds the GTPase binding domain, mimicking interactions of the VCA domain in autoinhibited WASP. [E.Coli O157:H7 strain not specified, EspF(U)] (Mus musculus) PubMed

 957.

While deletion of the N-terminal affected the expression level of AIDA-I, the protein was still exported to the outer membrane and glycosylated. [AIDA-I] (Mus musculus) PubMed

 958.

Results provide experimental evidence for the existence of a stable half-barrel subdomain in the (beta/alpha)8-barrel fold of TrpF [TrpF]. (Mus musculus) PubMed

 959.

the solution structure of the apo-thiolation-thioesterase (T-TE) di-domain fragment of the Escherichia coli enterobactin synthetase EntF NRPS subunit [no strain specified; EntF] (Mus musculus) PubMed

 960.

demonstrate a magnetic-field effect on the photochemical yield of a flavin-tryptophan radical pair in Escherichia coli photolyase [no strain indicated, DNA photolyase] (Mus musculus) PubMed

 961.

A crystal structure of Cif is presented, revealing it to be a divergent member of the superfamily of enzymes including cysteine proteases and acetyltransferases that share a common catalytic triad.[Cif] (Mus musculus) PubMed

 962.

crystal structure of Escherichia coli bacterioferritin has been solved to 1.9 A [bacterioferritin] (Mus musculus) PubMed

 963.

Antisense ribozymes that act on the DNA gyrase A subunit can also induce recA.[recA, DNA gyrase] (Mus musculus) PubMed

 964.

Hsp15 translocates the tRNA moiety from the A site to the P site of stalled 50S subunits. By stabilizing the tRNA in the P site, Hsp15 indirectly frees up the A site, allowing a release factor to land there and cleave off the tRNA. (Mus musculus) PubMed

 965.

Both flagellum filament assembly and the motor proteins MotA and MotB appeared to be required for E. coli AL511 uptake into collecting duct cells. [MotA, MotB] (Mus musculus) PubMed

 966.

In solution, the periplasmic loop P2 of MalF interacts with MalE in a manner independent of maltose. MalF-P2 adopts a well-defined tertiary structure independent of other parts of the transporter. (MalF) and (MalE) (Mus musculus) PubMed

 967.

Glu99 serves as a haem d ligand of cytochrome bd[cytochrome bd quinol oxidase, no strain indicated] (Mus musculus) PubMed

 968.

the unique electrostatic network of NhaA that connect the coupled clusters of the "pH sensor" with the binding site, which is crucial for pH activation of NhaA [NhaA, no strain indicated] (Mus musculus) PubMed

 969.

The structure of EcoO109I is intrinsically flexible in the direction of its functional movement, to facilitate effective structural changes for sequence-specific DNA recognition and processing.[EcoO109I] (Mus musculus) PubMed

 970.

Screening of the mammalian SH3 proteome for the ability to bind EspF(U) identified the SH3 domain of insulin receptor tyrosine kinase substrate (IRTKS), a factor known to regulate the cytoskeleton.[Tir, EspF(U)] (Mus musculus) PubMed

 971.

W44 of CusF protein is important in maintaining a moderate-affinity and solvent-shielded three-coordinate environment for Cu(I).[CusF] (Mus musculus) PubMed

 972.

Here we demonstrate that the yfiC gene of E. coli encodes an enzyme responsible for the methylation of A37 in tRNA(1)(Val). (Mus musculus) PubMed

 973.

The isolation and characterization of 2 closely related antigenic variants of fedA and their association with gastrointestinal disease in swine are reported.[fedA] (Mus musculus) PubMed

 974.

study describes structural means by which an enzyme that does not completely enclose its substrate evolved to achieve processive catalysis, and how interactions with DNA flanking the recognition site alter this processivity[DNA ADENINE METHYLTRANSFERASE] (Mus musculus) PubMed

 975.

Molecular dynamics study is presented to identify factors that contribute to PmrD protein's stability. [PmrD] (Mus musculus) PubMed

 976.

RecF pathway has many parallels with recombinational repair in eukaryotes [recF, unspecified strain] (Mus musculus) PubMed

 977.

qnrS1 gene was associated with a Tn3-like transposon[qnrs1] (Mus musculus) PubMed

 978.

The IscU-HscB complex exists as two (or more) distinct states that interconvert at a rate much faster than the rate of dissociation of the complex. HscB binds to and stabilizes the ordered state of apo-IscU. (HscB) and (IscU). (Mus musculus) PubMed

 979.

The structure of a monothiol GRX homodimer (Escherichia coli GRX4) coordinating a [Fe2S2] cluster is presented. (GRX4). (Mus musculus) PubMed

 980.

the function of threonine 44 in Escherichia coli dihydrodipicolinate synthase [dihydrodipicolinate synthase] (Mus musculus) PubMed

 981.

By repetitive element sequence-based PCR genotyping, genetic similarity was established for selected isolates. We believe this to be the first report of E. coli strains producing CNF1 in non-human primates. (cytotoxic necrotizing factor 1, cnf1) (Mus musculus) PubMed

 982.

There is a correlation between Pet secretion by enteroaggregative Escherichia coli, internalization of Pet into epithelial cells, cell detachment and cell death in EAEC-infected cells.[plasmid-encoded toxin (Pet)/ Escherichia coli 042] (Mus musculus) PubMed

 983.

The highest queous accessibility of subunit c of the F1F0 ATP is located in the cytoplasmic side of transmembrane helix 2 and in a pocket of residues around Asp-61. [subunit c of F1F0] (Mus musculus) PubMed

 984.

sodA, sodB, gor, trxA, gshA, grxA and marR have distinct roles in safeguarding or sensitizing cells to different toxic metal ions (Cr(2)O(7)(2-), Co(2+), Cu(2+), Ag(+), Zn(2+), AsO(2)(-), SeO(3)(2-) or TeO(3)(2-)). [sodA,sodB,gor,trxA,gshA,grxA and marR] (Mus musculus) PubMed

 985.

Electromagnetic coupling of hemes is important for facilitated heme-heme electron transfer in cytochrome bo. [cytochrome bo quinol oxidase] (Mus musculus) PubMed

 986.

The structure of the active site of ribonucleotide reductase A chain (PDB 1RIB) in the radical state (tyrosyl radical) was studied using EPR. [ribonucleotide reductase A chain (PDB 1RIB)] (Mus musculus) PubMed

 987.

The conformation of the membrane bound, closed channel state of colicin A was determined. (Mus musculus) PubMed

 988.

YidC functions as a membrane-based chaperone 'module' to facilitate assembly of a subset of protein complexes in the inner membrane of E. coli.[YidC; Mscl] (Mus musculus) PubMed

 989.

These data indicated that AzoR is a quinone reductase providing resistance to thiol-specific stress caused by electrophilic quinones.[AzoR] (Mus musculus) PubMed

 990.

This study reports mapping of the ybaW promoter and its expression; it recommends changing the name of the protein to fadM based on its regulation and metabolism.[fadM] (Mus musculus) PubMed

 991.

It was shown that over a range of intracellular NagB concentrations it is the quantity of the substrate, GlcN6P, which is limiting growth rather than N-acetylglucosamine-6-phosphate. (Mus musculus) PubMed

 992.

The transcriptional regulation of rraB, an inhibitor of RNase E is reported.[rraB; RNase E] (Mus musculus) PubMed

 993.

This study showed that, despite differences in FimH structure and fine receptor specificity, the shear-dependent nature of FimH-mediated adhesion is highly conserved between bacterial species.[FimH] (Mus musculus) PubMed

 994.

The role of the major periplasmic chaperones in the biogenesis of EspP, a prototype SPATE protein produced by Escherichia coli O157:H7 is reported.[EspP] (Mus musculus) PubMed

 995.

new details of the catalytic mechanism of 1-deoxy-D-xylulose 5-phosphate synthase [1-deoxy-D-xylulose 5-phosphate synthase] (Mus musculus) PubMed

 996.

the positively charged Skp targets OmpA to a negatively charged membrane, which facilitates the release of OmpA from its complex with Skp for subsequent folding and membrane insertion [E. coli, no strain indicated; ompA and Skp] (Mus musculus) PubMed

 997.

A glycine within a flexible beta-strand that links the aminoacylation and editing domains of leucyl-tRNA synthetase was determined to be important to tRNA translocation.[leucyl-tRNA synthetase] (Mus musculus) PubMed

 998.

Structural data of FaeG during different stages of the F4 fimbrial biogenesis process confirm the general principles of the donor strand complementation/exchange mechanisms taking place during pilus biogenesis.[FaeG] (Mus musculus) PubMed

 999.

PsiB binds to RecA protein that is free in solution. The RecA-PsiB complex impedes formation of RecA nucleoprotein filaments on DNA.(RecA) and (PsiB) (Mus musculus) PubMed

 1000.

A phylogenetic analysis of AAN82231 that shows it belongs to the DsbB subfamily of proteins is reported. (Mus musculus) PubMed

 1001.

Stabilization and bundling of FtsZ polymers by ZapA was inversely correlated to the GTPase activity of FtsZ.(FtsZ and ZapA) (Mus musculus) PubMed

 1002.

In the absence of EntB, EntE catalyzes the formation of Ap(4)A, which is implicated in regulating cell division during stress. EntE expression during iron starvation may produce Ap(4)A to slow growth until intracellular iron stores can be restored. (Mus musculus) PubMed

 1003.

The prevalence of cnf, hlyD, sfa, and papGIII in fecal Escherichia coli isolates from healthy dogs and their owners and their association with history of urinary tract infection are reported.[cnf; sfa; papGIII] (Mus musculus) PubMed

 1004.

cAMP switches the catabolite activator protein from the 'off' state (inactive), which binds DNA weakly and non-specifically, to the 'on' state (active), which binds DNA strongly and specifically [no strain indicated; catabolite activator protein] (Mus musculus) PubMed

 1005.

Rep and UvrD provide two contrasting solutions as to how organisms may promote replication of protein-bound DNA.[Rep] (Mus musculus) PubMed

 1006.

Omp1 shows a great sequence & structural homology to the family of outer membrane porins of enteric bacteria; Reconstitution of the purified protein into lipid bilayers demonstrated that it is a channel-forming component & slightly cation-selective[Omp1] (Mus musculus) PubMed

 1007.

ChiB hydrolyzes crystalline beta-chitin via a mechanism in which four exposed aromatic residues play important roles (Mus musculus) PubMed

 1008.

The digestion of the beta-chitin fibrils by ChiA occurred from the reducing end to the nonreducing end, whereas digestion by ChiB occurred from the non-reducing end to the reducing end [chiA & chiB] (Mus musculus) PubMed

 1009.

Amino acid substitution in the omega loop of chromosomal AmpC beta-lactamase in S. marcescens confers resistance to ceftazidime. (Mus musculus) PubMed

 1010.

swrW gene encoding putative serrawettin W1 synthetase was identified; putative SwrW was uni-modular nonribosomal peptide synthetase specifying only L-serine [swrW] (Mus musculus) PubMed

 1011.

chitin-binding protein CBP21 homologs occur in most chitin-degrading microorganisms,suggesting a general mechanism by which chitin-binding proteins enhance chitinolytic activity. (Mus musculus) PubMed

 1012.

Greater retention of the glycosyl fragment at the active site of the -3 mutant of Serratia marcescens chitinase A might favor transglycosylation due to a stabilized conformation of its D313 [chitinase A] (Mus musculus) PubMed

 1013.

characterization of polyphosphate operon; it is composed of a polyphosphate promoter, polyphosphate kinase (ppk) and exopolyphosphatase (ppx) [ppk, ppx] (Mus musculus) PubMed

 1014.

heme transfer from the soluble HasA hemophore to its membrane-bound receptor HasR is driven by protein-protein interaction from a high to a lower affinity binding site [HasA, HasR] (Mus musculus) PubMed

 1015.

SpnT might be involved in regulation of DNA replication and swarming-related phenomenon independent of SpnIR. (SpnT) (Mus musculus) PubMed

 1016.

HexS was shown as a LysR type transcriptional regulator; it was a transcriptional negative regulator of the genes swrW encoding serrawettin W1 synthase and PigA for prodigiosin synthesis [hexS] (Mus musculus) PubMed

 1017.

while DHasA can bind two heme molecules, it is not able to deliver them to the receptor HasR [HasA, HasR] (Mus musculus) PubMed

 1018.

loss of processivity in the W97A mutant was accompanied by a 29-fold increase in the degradation rate for single-polymer chains as present in the soluble chitin-derivative chitosan[chitinase B] (Mus musculus) PubMed

 1019.

Mutations in three extracellular loops of HasR abolished hemophore HasA binding both in vivo and in vitro [HasR, HasA] (Mus musculus) PubMed

 1020.

Together, these data support a model in which OxyR contributes to early stages of S. marcescens biofilm formation by influencing fimbrial gene expression.[OxyR] (Mus musculus) PubMed

 1021.

HasB is specific to heme uptake in the natural host and in Escherichia coli expressing the S. marcescens receptor HasR. (Mus musculus) PubMed

 1022.

These results indicate that SmdAB is probably a heterodimeric multidrug efflux pump of the ABC family in S. marcescens.[SmdA & SmdB, in strain Db10] (Mus musculus) PubMed

 1023.

E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149. [TME-149] (Mus musculus) PubMed

 1024.

Data show that S. marcescens HemTUV permease and HemTUV orthologs present in many gram-negative pathogens form a class of heme-specific permeases different from the Dpp peptide/heme permease characterized in E. coli. Gene Name: HemTUV permease (Mus musculus) PubMed

 1025.

Results indicated that activated RssA-RssB signaling directly inhibits flhDC(Sm) promoter activity at 37 degrees C, and this inhibitory effect was comparatively alleviated at 30 degrees C [flhD, flhC, RssA and RssB] (Mus musculus) PubMed

 1026.

The gene responsible for multidrug resistance from chromosomal DNA of Serratia marcescens has been cloned. (Mus musculus) PubMed

 1027.

The high specificity of the interaction with the (non-chitinous) column material is mediated by aromatic residues that occur in the substrate-binding clefts and surfaces of the enzymes[chitinase C1] (Mus musculus) PubMed

 1028.

Three tryptic peptides of the chitosanase are identical to a chitin-binding protein Cbp21 from S. marcescens with 63% sequence coverage. (chitosanase) (Mus musculus) PubMed

 1029.

rssC is hierarchically classified as class II members in FlhDC(Sm) regulon, and reciprocally defect in rssC results in aberrant swarming and hypervirulence in S. marcescens.(rssC) (Mus musculus) PubMed

 1030.

SdeCDE knockout strains showed no change in antibiotic susceptibility in comparison with the parental strains for any of the substrates.[SdeC, SdeD, SdeE] (Mus musculus) PubMed

 1031.

in addition to uptake as N,N'-diacetylchitobiose, a proportion of the N,N'-diacetylchitobiose is converted to N-acetylglucosamine by chitobiase, mainly in the periplasm, and incorporated into the cytoplasm by NagE.[chitobiase in strain 2170] (Mus musculus) PubMed

 1032.

SpnR acted as a negative regulator for the production of prodigiosin, swarming motility and biofilm formation, which were regulated by quorum sensing.[SpnR] (Mus musculus) PubMed

 1033.

mutations in components of the catabolite repression system (cyaA and crp) eliminate flagellum production and swimming motility. [cyaA, crp] (Mus musculus) PubMed

 1034.

role of the (alpha+beta) domain on the stability, catalytic activity and specificity of chitinase A was investigated [chitinase A] (Mus musculus) PubMed

 1035.

Three structures of the Serratia marcescens receptor HasR in complex with its hemophore HasA, are presented.[hasA, HasR] (Mus musculus) PubMed

 1036.

Results characterize the hydrolytic activities of the chitinase B mutants toward beta-chitin and the soluble chitin-derivative chitosan. (Mus musculus) PubMed

 1037.

the topology of GtrII has been determined [gtrII] (Mus musculus) PubMed

 1038.

identified ospD1 as a gene whose product negatively controls expression of genes regulated by secretion activity; evidence presented that OspD1 associates with the chaperone Spa15 and MxiE and acts as an anti-activator until it is secreted [OspD1] (Mus musculus) PubMed

 1039.

OspG negatively controls the host innate response induced by S. flexneri upon invasion of the epithelium. (Mus musculus) PubMed

 1040.

role of Fur and RyhB in the regulation of acid resistance [Fur, RyhB] (Mus musculus) PubMed

 1041.

YfiH protein could participate in the same pyrimidine salvage pathway as sfhB gene product[YfiH] (Mus musculus) PubMed

 1042.

Expression of both the sit and mntH promoters was repressed by either iron or manganese, partially dependent upon Fur and MntR, respectively. Only the mntH promoter exhibited OxyR-dependent induction in the presence of hydrogen peroxide. [SitA, MntH] (Mus musculus) PubMed

 1043.

report the crystal structure of YidB protein at 1.45 A resolution[YidB] (Mus musculus) PubMed

 1044.

OspF and OspC1 are essential for polymorphonuclear transepithelial migration. (OspF) (OspC1) (Mus musculus) PubMed

 1045.

A Shigella flexneri protein effector OspF as a dually specific phosphatase that dephosphorylated mitogen-activated protein kinases in the nucleus, was identified. (Mus musculus) PubMed

 1046.

effects of OspF on the host immune signaling pathways, including those of nuclear factor kappaB(NFkappaB) and MAPKs [OspF] (Mus musculus) PubMed

 1047.

IscR was a positive regulator of suf expression in the presence of hydrogen peroxide and a negative regulator of isc expression in the absence of hydrogen peroxide.[IscR in strain SA100] (Mus musculus) PubMed

 1048.

We found that coiled-coil regions (CCRs) 2 and 3 are necessary for wild-type Oag chain length regulation by Wzz.[Wzz in strain RMA2162] (Mus musculus) PubMed

 1049.

These results suggest that induction of OspF is enhanced during Shigella invasion of dendritic cells and decreases the phosphorylation level of Erk1/2.[OspF] (Mus musculus) PubMed

 1050.

The crystal structure of a periplasmic l-aspartate/l-glutamate binding protein (DEBP) from Shigella flexneri complexed with an l-glutamate molecule has been determined and refined to an atomic resolution of 1.0 A.[DEBP] (Mus musculus) PubMed

 1051.

The authors present a characterization of the native T3SS ATPase, Spa47, from the cytoplasm of Shigella flexneri, demonstrating it to be in two distinct high-molecular-weight complexes with Spa33: MxiN and MxiK.[Spa47 in strain M90T] (Mus musculus) PubMed

 1052.

determination of the crystal structure of VirA at 3.0 A resolution; the fold of VirA is unique and does not resemble that of any known protein [VirA] (Mus musculus) PubMed

 1053.

Cys363 within a conserved CXD motif acts as a nucleophile to catalyze ubiquitin transfer through a transthiolation reaction.[IpaH3 in strain 301] (Mus musculus) PubMed

 1054.

The residues 206-246 are required for Spa32 binding to the C-terminus of Spa40, an inner membrane protein required for Ipa proteins secretion. (Spa32)(Spa40) (Mus musculus) PubMed

 1055.

Overexpression of AcrA gene leads to multidrug resistance in clinical isolates of S. flexneri, and ciprofloxacin acquired susceptible to S. flexneri with Phe-Arg-beta-naphthylamide.[AcrA] (Mus musculus) PubMed

 1056.

Findings are consistent with a model in which Skp plays a critical role in the chaperoning of the alpha-domain of IcsA during transit through the periplasm: [Skp] (Mus musculus) PubMed

 1057.

Interaction of lipids with IpaB inducec IpaC localization at the needle tip concomitant with translocon insertion into the host membrane and type III secretion induction.[IpaC] (Mus musculus) PubMed

 1058.

single base substitution in the oriCIvc of the classical biotype has a significant effect on its replication initiation. [oriC] (Mus musculus) PubMed

 1059.

Results define the elements on the phage genome and bacterial chromosome required for CTXphi integration by XerC amd XerD [XerC, XerD] (Mus musculus) PubMed

 1060.

TcpH regulates virulence gene expression by controlling transcription activator TcpP proteolysis [TcpH,TcpP strain 0395] (Mus musculus) PubMed

 1061.

Data report the crystal structure of the transcriptional activator AphA to 2.2 angstrom resolution [AphA]. (Mus musculus) PubMed

 1062.

crystal structure of the outer membrane protein VceC from Vibrio cholerae (Mus musculus) PubMed

 1063.

Identification of a complex of TcpC protein and TcpQ protein in the development of the V. cholerae pilus. [TcpC, TcpQ] (Mus musculus) PubMed

 1064.

results indicate that HapR autorepresses from a single binding site in the hapR promoter and suggest a model for the temporal regulation of its expression as its intracellular levels increase[HapR] (Mus musculus) PubMed

 1065.

results suggest that the differences in FlrC binding to various flagellar promoters results in the differences in transcription levels that mirror the relative requirement for the flagellar components within the flagellum [FlrC] (Mus musculus) PubMed

 1066.

The dimer of EpsL in this complex is very similar to the dimer seen in the crystal structure of the native cytoplasmic domain of EpsL [EpsL, EpsE] (Mus musculus) PubMed

 1067.

identification of the ToxT binding sites located between acfA and acfD required for transcriptional activation of both genes[ToxT, acfA, AcfD] (Mus musculus) PubMed

 1068.

clpB1 insertion mutant showed increased sensitivity towards high temperature, oxidative stress, and acid pH. ClpB1 also conferred thermotolerance to V. cholerae [ClpB1] (Mus musculus) PubMed

 1069.

results provide a model for how the genes in the acetoin biosynthetic operon are regulated in V. cholerae by AlsR and AphA in response to environmental signals [AlsR, AphA] (Mus musculus) PubMed

 1070.

Crystal structures of a cholera toxin A1 subunit (CTA1):ARF6-GTP (guanosine triphosphate) complex reveal that binding of the human activator elicits dramatic changes in CTA1 subunit loop regions that allow NAD+ to bind to the active site [CTA1] (Mus musculus) PubMed

 1071.

small regulatory RNA with diverse functions, ranging from iron homeostasis to the regulation of biofilm formation [RyhB] (Mus musculus) PubMed

 1072.

neruaminidase (VCNA)Asp-576 & Arg-577 were specifically labeled with fluorescent substrate suggesting that a flexible beta-turn structure containing this sequence may have a role in the dynamic nature of substrate recognition & catalytic action [VCNA] (Mus musculus) PubMed

 1073.

role of NspS in V. cholerae biofilm development; norspermidine activates biofilm formation in an MbaA- and NspS-dependent manner [NspS] (Mus musculus) PubMed

 1074.

results provide a model for a two-domain structure for ToxT, with an N-terminal dimerization and environmental sensing domain and a C-terminal DNA-binding domain. [ToxT] (Mus musculus) PubMed

 1075.

Fur has both positive and negative regulatory functions in virulence of Vibrio cholerae. (Fur) (Mus musculus) PubMed

 1076.

identification of GbpA protein required for efficient intestinal colonization that mediates attachment to both zooplankton and human epithelial cells by binding to a sugar present on both surfaces [GbpA] (Mus musculus) PubMed

 1077.

report X-ray crystal structures of T1485 and T1512 and compare them with other structures of similar fold and discuss the putative active site [T1485 and T1512] (Mus musculus) PubMed

 1078.

VC0702 may have a biochemical function that involves NTP binding and phosphatase activity of some kind, and is likely involved in regulation of the signaling pathway [VC0702] (Mus musculus) PubMed

 1079.

In V. cholerae, VqmA regulates hapR transcription directly by binding to its promoter region and expression of vqmA is cell density dependent and autoregulated. [VqmA; HapR] (Mus musculus) PubMed

 1080.

CTA1 utilizes the A1(3) subdomain for functional interaction with ADP-ribosylation factor (ARF) 6 and for efficient expression of in vivo enzyme activity (Mus musculus) PubMed

 1081.

ToxT binds independently as a monomer to each toxbox in the tcpA direct repeat. (ToxT) (tcpA) (Mus musculus) PubMed

 1082.

the crystal structure of an integron integrase (Vibrio cholerae IntIA) bound to an attC substrate [IntIA] (Mus musculus) PubMed

 1083.

Results demonstrate a key role for PrtV in Vibrio cholerae interaction with grazing predators [PrtV]. (Mus musculus) PubMed

 1084.

iron transport systems, including a homologue of the ferrous transporter Feo and a periplasmic binding protein-dependent ATP binding cassette (ABC) transport system, termed Fbp, were identified in the V. cholerae genome sequence. [Feo, Fbp] (Mus musculus) PubMed

 1085.

Results describe the structure and function of both periplasmic domains of EpsC [EpsC]. (Mus musculus) PubMed

 1086.

Repression of type IV mannose-sensitive hemagglutinin (MSHA) was mediated by the key virulence transcription factor ToxT, indicating that V. cholerae is able to coordinate both virulence gene activation and repression.[ToxT] (Mus musculus) PubMed

 1087.

HlyU exhibits structural features common to the SmtB/ArsR family of transcriptional repressors (HlyU). (Mus musculus) PubMed

 1088.

EpsE ATP hydrolysis is stimulated by EpsL and acidic phospholipids [EpsL, EpsE] (Mus musculus) PubMed

 1089.

Study identifies the nucleoid protein Fis as playing a major role in the V. cholerae quorum-sensing circuit.[Fis protein] (Mus musculus) PubMed

 1090.

The vpvC allele found in the rugose genetic background is more active at producing c-di-GMP while that in smooth genetic background is less active. [vpvC] (Mus musculus) PubMed

 1091.

We found that gene expression of this PTS system is influenced by catabolite regulation and also by an Mlc homologue (VC2007), which in E. coli is a global regulator of sugar metabolism. [Mlc] (Mus musculus) PubMed

 1092.

the essential function of CgtA is as a repressor of the stringent response that acts by regulating SpoT activity to maintain low ppGpp levels when bacteria are growing in a nutrient-rich environment [CgtA, SpoT] (Mus musculus) PubMed

 1093.

The results here provide a model for the dual activation of the aphA promoter by Lrp and VpsR as well as its dual repression by HapR and AphA.[HapR, AphA, Lrp, VspR] (Mus musculus) PubMed

 1094.

The crystal structure of HapR to 2.2-A resolution reveals a dimeric, two-domain molecule with an all-helical structure that is strongly conserved with members of the TetR family of transcriptional regulators.[HapR protein] (Mus musculus) PubMed

 1095.

These data provide compelling evidence of a role for dynamics in the catalytic cycle of DsbA.[DsbA] (Mus musculus) PubMed

 1096.

It was shown that under hydrodynamic conditions biofilms were formed independent of VspA and LuxO but were controlled by expression of RpoS a negative regulator of VpsA. [VpsA, LuxO, RpoS] (Mus musculus) PubMed

 1097.

The ability of V. cholerae to prevent clearance and establish this prolonged colonization was associated with the accessory toxins hemolysin, the multifunctional autoprocessing RTX toxin, and hemagglutinin/protease.[HlaA, RtxA, HapA] (Mus musculus) PubMed

 1098.

Hemolysin had the predominant role in lethality, with a secondary contribution by the multifunctional autoprocessing RTX (MARTX) toxin.[HlyA, RtxA] (Mus musculus) PubMed

 1099.

Our results indicate that cyclic AMP receptor protein (CRP) plays a crucial role in the V. cholerae life cycle by affecting quorum sensing and multiple genes required for survival of V. cholerae in the human host and the environment. [CRP] (Mus musculus) PubMed

 1100.

characterization of a unique chitin oligosaccharide deacetylase involved in chitin catabolic cascade in the marine bacterium Vibrio cholerae [chitin oligosaccharide deacetylase] (Mus musculus) PubMed

 1101.

results indicate that specific residues of OmpU play different roles in controlling the passage of various compounds [OmpU] (Mus musculus) PubMed

 1102.

these results support a main role of HlyA in the pathogenesis of the CT gene-negative V. cholerae non-O1, non-O139 strain and identify apoptosis as a previously unrecognized cell death pathway triggered by HlyA.[HlyA in strain VC175] (Mus musculus) PubMed

 1103.

results suggest a model for the regulatory input of cyclic AMP (cAMP) receptor protein (CRP) on exopolysaccharide biosynthesis [CRP] (Mus musculus) PubMed

 1104.

Analysis of the truncated EpsM mutants revealed that the region of EpsM from amino acids 100 to 135 is necessary for EpsM to form homo-oligomers, while residues 84 to 99 appear to be critical for a stable interaction with EpsL. [EpsM, EpsL] (Mus musculus) PubMed

 1105.

Comparison among 4 x-ray structures of MsbA, trapped in different conformations (2 nucleotide-bound structures & 2 without nucleotide) reveals a flexible hinge formed by extracellular loops 2 & 3, allowing large ranges of motion. MsbA. (Mus musculus) PubMed

 1106.

FabV defines a new class of enoyl-ACP reductase.[FabV] (Mus musculus) PubMed

 1107.

The 3D structure of hemagglutinin/protease [HA/P (vibriolysin)] was predicted based on its sequence homology with Pseudomonas aeruginosa elastase (HA/P). (Mus musculus) PubMed

 1108.

study found that the major MSHA pilin, MshA, was degraded in V. cholerae in a TcpJ-dependent fashion [MSHA, TcpJ] (Mus musculus) PubMed

 1109.

Data show that HapR, a major regulator of quorum sensing, binds to and directly represses the expression of the biofilm transcriptional activator, vpsT [vpsT] (Mus musculus) PubMed

 1110.

Results identify the key structural elements which complement the N-terminal part of FliMV and explain how the structure, shape, and surface properties of the FliM binding pocket of other CheYVs abrogate this function [FliM]. (Mus musculus) PubMed

 1111.

environmental strains of V. cholerae isolated from different aquatic biotopes in Kerala produced toxigenic non-O1/non-O139 strains harboring CTX genetic element, heat-stable enterotoxin, rtxA gene, El Tor hemolysin, & Vibrio pathogenicity island.[rtxA] (Mus musculus) PubMed

 1112.

Lrp negatively regulates its own gene in E. coli, and was shown to do so even more strongly in P. mirabilis, Lrp appears to activate its own gene in V. cholerae.[Lrp] (Mus musculus) PubMed

 1113.

LqsA and CqsA belong to a family of pyridoxal 5'-phosphate-dependent autoinducer synthases, which produce the alpha-hydroxyketone signaling molecules LAI-1 and CAI-1 (Mus musculus) PubMed

 1114.

The extracellular matrix components fibronectin and fibrinogen were degraded by PrtV (PrtV). (Mus musculus) PubMed

 1115.

The X-ray crystal structure of lysostaphindetermined at 1.9-A resolution, is reported.[Lysostaphin] (Mus musculus) PubMed

 1116.

study found that the Vibrio cholerae hemolysin HlyA oligomer induced the expression of CXCR3 on B-1a cells [HlyA] (Mus musculus) PubMed

 1117.

The data indicate that VciB functions by promoting iron uptake via a ferrous, but not ferric, iron transport system: [VciB] (Mus musculus) PubMed

 1118.

hapR expression is also modulated by the regulatory network that governs flagellar assembly[hapR litR] (Mus musculus) PubMed

 1119.

Cholera toxin B, a component of Vibrio cholerae, promotes autoantibody production and glomerulonephritis in lupus-prone mice by enhancing lipid raft aggregation in T cells. (cholera toxin B) (Mus musculus) PubMed

 1120.

study identified two new genes, cdgG & cdgH, involved in rugosity control; determined that CdgH acts as a diguanylate cyclase (DGC) and positively regulates rugosity, whereas CdgG does not have DGC activity and negatively regulates rugosity [CdgG, CdgH] (Mus musculus) PubMed

 1121.

Helical arrays of membrane reconstituted MsbA are sensitive to subtle conformational changes induced by various transition state inhibitors. (MsbA) (Mus musculus) PubMed

 1122.

Vibrio cholerae ToxT uses different mechanisms in transcriptional regulation of pro- and anticolonization factors. [ToxT] (Mus musculus) PubMed

 1123.

The authors provide evidence that EpsD is critical to the localization of EpsC and EpsM and perhaps their assembly into the T2S complex.[EpsD & EpsC & EpsM] (Mus musculus) PubMed

 1124.

analysis provides evidence that HapR binds to two distinct binding motifs and has led to the identification of several novel HapR-regulated targets in V. cholerae (HapR). (Mus musculus) PubMed

 1125.

ACT domain is essential for (p)ppGpp hydrolase activity of SpoT. [SpoT] (Mus musculus) PubMed

 1126.

This transcriptional regulator, OscR (osmolarity controlled regulator), was found to modulate the transcription of genes involved in biofilm matrix production and motility in a salinity-dependent manner. New Gene: OscR (Mus musculus) PubMed

 1127.

Data indicate that FlhF establishes the site of flagellum assembly at the old cell pole membrane by recruiting the earliest flagellar structural component FliF [FlhF]. (Mus musculus) PubMed

 1128.

preliminary X-ray studies to 1.71 A resolution.[EpsH] (Mus musculus) PubMed

 1129.

Data present the apo- and PLP-bound crystal structures of CqsA and confirm that it shares structural homology with the dimeric alpha-oxoamine synthases, including a conserved PLP-binding site [CqsA]. (Mus musculus) PubMed

 1130.

Results suggest a model in which GbpA levels fluctuate in concert with the bacterial production of proteases in response to quorum-sensing signals. [GbpA] (Mus musculus) PubMed

 1131.

This study showed that PhoB regulates an operon, acgAB, which encodes cyclic diguanylic acid metabolic enzymes and that induction of acgAB by PhoB positively regulates V. cholerae motility and acgAB expression during late stages of cholera in mice. (Mus musculus) PubMed

 1132.

The pH optimum of MgPP(i) hydrolysis by PPase was shifted to more alkaline pH due to higher values of the pK(a) of ionizable groups for both the free enzyme and the enzyme-substrate complex. [PPase] (Mus musculus) PubMed

 1133.

Thermal instability in the CTA1 subunit-specifically, the loss of CTA1 tertiary structure at 37 degrees C-triggers toxin dislocation.[CTA1] (Mus musculus) PubMed

 1134.

V. cholerae biofilm and planktonic cells differ in cell-to-cell communication by differentially responding to autoinducer 2. A V. cholerae luxS (autoinducer-2-defective) mutant made increased biofilm. [autoinducer 2/AI-2/Vibrio cholerae strain C7258] (Mus musculus) PubMed

 1135.

The regulation of thermostable direct hemolysin-related hemolysin (trh) transcription via its promoter region in V. parahaemolyticus. [trh] (Mus musculus) PubMed

 1136.

vpaH affects lateral flagellum biogenesis in trh-positive Vibrio parahaemolyticus strain TH3996 [vpaH] (Mus musculus) PubMed

 1137.

Three new regulators of swarming, swrZ, swrT, and opaR [swrZ, swrT, and opaR] (Mus musculus) PubMed

 1138.

These results indicate that the pvsC gene product functions as an inner membrane exporter of vibrioferrin. [PvsC] (Mus musculus) PubMed

 1139.

Two proteins, psuA and pvuA, are immunogenic and can produce synergistic effects during in vivo infection. (psuA and pvuA) (Mus musculus) PubMed

 1140.

Vibrio VopL is predicted to be a bacterial virulence factor that disrupts actin homeostasis during an enteric infection of the host. (Mus musculus) PubMed

 1141.

ScrC has intrinsic diguanylate cyclase and phosphodiesterase activities, that are controlled by ScrAB. Specifically, ScrC acts to form c-di-GMP and the phosphodiesterase activity plays a dominant role during surface translocation and in biofilms. [ScrC] (Mus musculus) PubMed

 1142.

The cytotoxicity against flounder gill cells and fish pathogenicity indicated a potential role for the zinc metalloprotease in pathogenesis. [Zinc metalloprotease] (Mus musculus) PubMed

 1143.

VmeA and VmeB genes encode an RND type of multidrug efflux transporter. [VmeA, VmeB] (Mus musculus) PubMed

 1144.

These phenotypes were abrogated in a mutant strain lacking the CI-T3S effector Vp1686, suggesting that the inhibiting actin polymerization may be a downstream effect of Vp1686-dependent GTPase inhibition.[Vp1686 in strain BCC23] (Mus musculus) PubMed

 1145.

ExsA positively regulates the expression and secretion of Vp1656 while ExsD negatively regulates the expression and secretion of Vp1656. [ExsA, ExsD] (Mus musculus) PubMed

 1146.

Results support insertion sequence-mediated partial tdh deletion resulted in the emergence of the tdh(-) strain (tdh). (Mus musculus) PubMed

 1147.

study reports the crystal structure of a member of the solute sodium symporters, the Vibrio parahaemolyticus sodium/galactose symporter [SGLT] (Mus musculus) PubMed

 1148.

These findings demonstrated the behavior of MreB in the morphological changes of V. parahaemolyticus under intrinsic or extrinsic stresses.[MreB in strain 1137] (Mus musculus) PubMed

 1149.

VopQ is a type III secreted effector essential for T3SS1-mediated cytotoxicity that induces autophagy during infection in a phosphatidylinositol-3-kinase-independent manner. [VopQ] (Mus musculus) PubMed

 1150.

Results suggest that Vibrio vulnificus hemolyin/cytolysin VvhA is substantially produced in vivo and would contribute to the pathogenesis of V. vulnificus septicemia [VvhA strain MO6-24/O] (Mus musculus) PubMed

 1151.

adenylate cyclase of V. vulnificus appeared to play a global regulatory role in the expression of various virulence factors[cya, adenylate cyclase] (Mus musculus) PubMed

 1152.

cloning and characterization of PilA; role in bioilm formation, adherence to epithelial cells, and virulence. [PilA] (Mus musculus) PubMed

 1153.

cadBA genes were transcribed as a transcriptional operon by a single promoter, P(cadBA), which was activated by CadC in a pH-dependent manner [CadC] (Mus musculus) PubMed

 1154.

flagellin FlaB would serve as an efficacious mucosal adjuvant inducing protective immune responses through TLR5 activation. (FlaB) (Mus musculus) PubMed

 1155.

Essential in both the pathogenesis and the capsular polysaccharide biosynthesis of V. vulnificus. (wbpP, UDP-N-acetyl-D-glucosamine C4 epimerase) (Mus musculus) PubMed

 1156.

findings demonstrate that PGI-LysAP has broad exopeptidase activity which may enhance V. vulnificus invasiveness by altering peptides involved in signal transduction pathways [PGI-LysAP] (Mus musculus) PubMed

 1157.

Cyclo(Phe-Pro)produced by Vibrio vulnificus upregulates the expression of ompU [ompU] (Mus musculus) PubMed

 1158.

PutR and CRP coactivate the expression of putAP operon promoter and exert their effect by cooperatively binding to the promoter. (PutR) (cAMP receptor protein) (Mus musculus) PubMed

 1159.

vvhA expression in swarming V. vulnificus is downregulated via the activity of the LuxS quorum-sensing system. (vvhA) (luxS) (Mus musculus) PubMed

 1160.

these results demonstrate that AphB and CadC function sequentially in a regulatory cascade to activate cadBA expression and that AphB activates the expression of cadC by directly binding to an upstream region of P(cadC).[AphB, CadC] (Mus musculus) PubMed

 1161.

This study indicates that OmpU is an important virulence factor involved in the adherence of V. vulnificus to the host cells. (Mus musculus) PubMed

 1162.

SoxR induces CadA (lysine decarboxylase)in response to superoxide stress [SoxR, CadA] (Mus musculus) PubMed

 1163.

study demonstrates novel findings that NtrC is involved in biofilm formation and that NtrC modulates LPS and EPS production via controlling expression of the gene encoding an ADP-glycero-manno-heptose-6-epimerase(gmhD) [ntrC, gmhD] (Mus musculus) PubMed

 1164.

VvpE has a role in the surface adherence and colonization of V. vulnificus by facilitating swarming, and in the mucosal invasion of V. vulnificus by destroying IgA and lactoferrin. (Mus musculus) PubMed

 1165.

These findings suggest that interaction with membrane cholesterol is required for activity of Vibrio vulnificus cytolysin. (VVC) (Mus musculus) PubMed

 1166.

Loss of PilD or PilA significantly reduces the ability of V. vulnificus to persist in Crassostrea virginica over a 66-h interval, strongly suggesting that pili expressed by this bacterium play a role in colonization or persistence in oysters. [PilD, PilA] (Mus musculus) PubMed

 1167.

IlpA of V. vulnificus functions as an immunostimulant to human cells via TLR2 (Mus musculus) PubMed

 1168.

results indicate that phospholipase A (PLA)activity is important in V. vulnificus-induced cytotoxicity and lethality, suggesting a crucial role for PLA in the pathogenesis of V. vulnificus infection [PLA] (Mus musculus) PubMed

 1169.

gne, but not galE, is essential for LPS biosynthesis and virulence in the zoonotic serovar of V. vulnificus biotype 2 [gne] (Mus musculus) PubMed

 1170.

Nonribosomal peptide synthase genes (vvsA, vvsB) are responsible for the biosynthesis of siderophore in Vibrio vulnificus MO6-24/O are important for virulence of the pathogen in a mice model. [vvsA, vvsB] (Mus musculus) PubMed

 1171.

Metalloprotease (vvp) and the extracellular serine protease (vvhA) contribute to pathogenicity of V. vulnificus. [vvp, vvhA] (Mus musculus) PubMed

 1172.

The 34 kDa-VvpE is the major form secreted along with 45 kDa-VvpE from the early growth phase via the PilD-mediated type II general secretion system. [VvpE, pilD] (Mus musculus) PubMed

 1173.

These results provide evidence that csrA inhibits biofilm formation in V. vulnificus.[CsrA] (Mus musculus) PubMed

 1174.

We conclude that fadR and regulation of fatty acid metabolism are essential for V. vulnificus to be able to cause disease in mammalian hosts.[FadR] (Mus musculus) PubMed

 1175.

Taken together, these results indicate that V. vulnificus RtxA toxin induces the apoptotic death through a mitochondria-dependent pathway in human intestinal epithelial cells exposed to V. vulnificus.[RtxA in strain MO6-24/O (Mus musculus) PubMed

 1176.

Vvp is not an essential lesional factor. [vvp] (Mus musculus) PubMed

 1177.

CadC and leucine responsive regulatory protein (Lrp) function cooperatively to activate the cadBA operon rather than sequentially in a regulatory cascade. [CadC, Lrp] (Mus musculus) PubMed

 1178.

The quaternary structure of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus was determined after co-crystallization with a nanobody. (EpsI and EpsJ). (Mus musculus) PubMed

 1179.

HupA of V. vulnificus is essential for survival and multiplication during infection. (Mus musculus) PubMed

 1180.

Two regulators of ribonuclease activity, RraAV1 and RraAV2, have both a conserved inhibitory function and a differential inhibitory activity on RNase E-like enzymes across the species. (RraAV1)(RraAV2) (Mus musculus) PubMed

 1181.

The nanA mutant was significantly diminished in growth with and adherence to INT-407 epithelial cells in vitro, and was defective for intestinal colonization.[NanA] (Mus musculus) PubMed

 1182.

pilA allelic diversity and horizontal movement is maintained in the population by both diversifying and frequency-dependent selection most likely to escape shellfish innate immunity defense or lytic phages.[pilA] (Mus musculus) PubMed

 1183.

These results indicate that iron increases extracellular VvhA secretion via the type II general secretion system, although it can repress vvhA transcription via Fur.[vvhA] (Mus musculus) PubMed

 1184.

Low temperature incubation of the parent resulted in loss of catalase activity, making the cells H(2)O(2) sensitive, and paralleling the loss of culturability (entry into the viable but nonculturable state).[catalase] (Mus musculus) PubMed

 1185.

resultant data show that C. trachomatis DcrA binds to native chlamydial genomic sequences and, overall, substantiate a functional relationship between chlamydial DcrA and the Fur family of regulators [DcrA strain E/UW-5CX] (Mus musculus) PubMed

 1186.

concluded that PrmC functions as an N5-glutamine AdoMet-dependent MTase, involved in methylation of release factors [PrmC strain L2/434/Bu] (Mus musculus) PubMed

 1187.

Functional surface expression, coupled with improved understanding of major outer membrane protein (MOMP) topology, could provide modified antigens for immunological studies and vaccination, including live subunit vaccines.[MOMP] (Mus musculus) PubMed

 1188.

GroEL increased the ability of HrcA to bind to the CIRCE operator and to repress transcription [GroEL, HrcA] (Mus musculus) PubMed

 1189.

The association between clinical symptoms and ompA genotype or serotype in patients with C. trachomatis infections is presented.[ompA] (Mus musculus) PubMed

 1190.

cloning and expression of Chlamydia trachomatis inclusion membrane protein genes IncB and IncC in Escherichia coli. [IncB, INcC] (Mus musculus) PubMed

 1191.

These findings provide the first genetic proof that TrpR acts as a negative regulator of transcription in C. trachomatis. (Mus musculus) PubMed

 1192.

The omp1 gene was highly conserved for genotype E and F, but less conserved for other genotypes. [omp1] (Mus musculus) PubMed

 1193.

ChlaDub1 and ChlaDub2 represent the first known bacterial deubiquitinating enzymes (DUBs) that possess both deubiquitinating and deneddylating activities. (Mus musculus) PubMed

 1194.

CT229 of Chlamydia trachomatis interacts with and recruits Rab4A to the inclusion membrane and therefore may play a role in regulating the intracellular trafficking or fusogenicity of the chlamydial inclusion.(CT229) (Mus musculus) PubMed

 1195.

results indicate RNAP containing sigma(28) is capable of recognizing some but not all E coli sigma(28)-dependent promoters & it can distinguish different promoter structures, preferentially activating promoters with upstream AT-rich sequences [sigma28] (Mus musculus) PubMed

 1196.

Results reveal a mechanism by which chlamydiae induce localized cytoskeletal changes by the translocated effector TARP (translocated actin recruiting phosphoprotein) during entry into host cells [TARP]. (Mus musculus) PubMed

 1197.

chlamydial protease-like activity factor mediated anti-chlamydial immunity is highly dependent upon antigen-specific CD4(+) T cells[chlamydial protease-like activity factor] (Mus musculus) PubMed

 1198.

We found that expression of cHsp60-2 is responsive to iron deprivation in endometrial epitheliala cells in vitro. [Hsp60-2] (Mus musculus) PubMed

 1199.

LpxD is the N-acyltransferase of lipid A biosynthesis [LpxD for serovar B] (Mus musculus) PubMed

 1200.

A novel C. trachomatis antihost protein whose activity is relevant to chlamydial pathogenesis has been discovered.[CT847] (Mus musculus) PubMed

 1201.

chaperone activity may involve functional protease domain and that Chlamydia trachomatis HtrA functions as both a chaperone and protease at 37 degrees C[ HtrA ] (Mus musculus) PubMed

 1202.

Data show that CdsF is concentrated in the outer membrane of elementary bodies and is surface exposed as a component of an extracellular needle-like projection, and could serve as an efficacious target for anti-Chlamydia neutralizing antibodies[CdsF] (Mus musculus) PubMed

 1203.

Examination of the reactivities of three stable redox states of the Mn/Fe cluster of ribonucleotide reductase R2 subunit toward hydrogen peroxide (ribonucleotide reductase R2). (Mus musculus) PubMed

 1204.

F41A mutation increases the K(M) for UDP-3-O-(R-3-OHC14)-GlcN 30-fold, consistent with aromatic stacking of the corresponding F43 side chain against the uracil moiety of bound UDP-GlcNAc in the X-ray structure of Chlamydia trachomatis LpxD[LpxD] (Mus musculus) PubMed

 1205.

Tarp harbors a sequence similar to a Src and Abl kinase consensus target. (Tarp) (Mus musculus) PubMed

 1206.

cHSP60 and cHSP10 could affect mucosal immune function by increasing the release of IFN-gamma, IL-10 and TNF-alpha by cervical mononuclear cells. HSP60. HSP10. (Mus musculus) PubMed

 1207.

ChlaDub1 is capable of inhibiting IkappaBalpha degradation and blocking NF-kappaB activation. (ChlaDub1) (Mus musculus) PubMed

 1208.

7 of the 12 sigma-66 promoters were poorly conserved across C. trachomatis, Chlamydia pneumoniae and Chlamydia caviae. [sigma-66] (Mus musculus) PubMed

 1209.

Amino acid residues E206, Y214, and E222 of sigma 28 contribute to interaction with the core RNA polymerase. [sigma 28] (Mus musculus) PubMed

 1210.

These results indicate that nectin-1 is degraded by chlamydial protease-like activity factor (CPAF) in C. trachomatis-infected genital epithelial cells, a novel strategy that Chlamydiae may use to aid their dissemination. [CPAF] (Mus musculus) PubMed

 1211.

The findings show that PmpD exists as two distinct forms, a surface-associated oligomer exhibiting a higher-order flower-like structure and a soluble form restricted to infected cells.[PmpD in strain L2/LGV-434] (Mus musculus) PubMed

 1212.

Tarp was translocated into the host cell cytoplasm where it is phosphorylated by a set of host protein kinases. [Tarp] (Mus musculus) PubMed

 1213.

the aminoacid sequences of the human HSP60 was compared with the bacterial counterpart to better elucidate how CTHSP60 may simulate HSP60 from human origin during infection and may induce an autoimmune response.(CTHSP60) (Mus musculus) PubMed

 1214.

Substrate cleavage is also correlated with processing of CPAF into N-terminal (CPAFn) and C-terminal (CPAFc) fragments, suggesting that these putative catalytic residues may also be required for CPAF maturation [CPAF] (Mus musculus) PubMed

 1215.

YtgA is an iron-binding protein that is influenced specifically by iron availability, and may be part of an ABC transporter system. [YtgA(CT067)/Chlamydia trachomatis E/UW-5/CX] (Mus musculus) PubMed

 1216.

Below the major thermal transition regions, nMOMP remains in its native conformation over the pH range of 3-8. Above the thermal transitions, nMOMP appears in two different structurally altered states; one at pH 3-5 and the other at pH 6-8. (MOMP) (Mus musculus) PubMed

 1217.

The authors demonstrated that CT621 is secreted late in the chlamydial developmental cycle and that it is the first chlamydial protein found to be localized within both the host cell cytoplasm and the nucleus.CT621] (Mus musculus) PubMed

 1218.

By use of UDP-MurNAc-L-Ala-D-Glu as the nucleotide substrate, MurE(Ct) demonstrated ATP-dependent meso-diaminopimelic acid ligase activity with pH and magnesium ion optima of 8.6 and 30 mM, respectively.[MurE] (Mus musculus) PubMed

 1219.

Results identify Tyt1 as the first bacterial NSS member consisting of only 11 TMs and shows that Tyt1 is a suitable model for the study of neurotransmitter:sodium symporter (NSS) dynamics and structure/function relationships of human NSSs [Tyt1}. (Mus musculus) PubMed

 1220.

X-ray structure; FadA exists in two forms: the intact form (pre-FadA), consisting of 129 amino acids, and the mature form (mFadA), which lacks an 18-residue signal sequence. The crystals belong to the hexagonal space group P6(1) or P6(5)[FadA]. (Mus musculus) PubMed

 1221.

FadA from Fusobacterium nucleatum secreted and nonsecreted forms are used for functional oligomerization for attachment and invasion of host cells (Mus musculus) PubMed

 1222.

Fnu_GT displayed the highest glycosylation activity when UDP-galactose was used as a donor nucleotide-sugar and heptose or Nacetylglucosamine as an acceptor sugar. [GT] (Mus musculus) PubMed

 1223.

[fomA] Conformation and orientation of membrane-incorporated FomA demonstrate by selective interaction with phosphatidylcholine bilayer membranes that FomA is not trimeric, and is consistent with a monomeric beta-barrel of 14-16 strands. (Mus musculus) PubMed

 1224.

Arginine-inhibitable adherence in co-aggregation and biofilm formation is specifically mediated by radD. [RadD] (Mus musculus) PubMed

 1225.

FadA plays an important role in F. nucleatum colonization in vivo. (Mus musculus) PubMed

 1226.

Recombinant GR from Fusobacterium nucleatum (FnGR), a Gram-negative anaerobe involved in periodontal disease, was overproduced, purified, and characterized. [glutamate racemase] (Mus musculus) PubMed

 1227.

R290 & F31 provide catalytic power for hydrolysis of both substrates, native residues are more important for 4NPX than 4NPA as xylopyranose ring must undergo greater distortion than arabinofuranose ring[beta-D-xylosidase/alpha-L-arabinofuranosidase] (Mus musculus) PubMed

 1228.

crystallization and structure at 1.8 A resolution of DNA photolyase devoid of its 8-HDF chromophore (apophotolyase) [DNA photolyase] (Mus musculus) PubMed

 1229.

crystal structure of DNA photolyase bound to duplex DNA that is bent by 50 degrees and comprises a synthetic cyclobutane pyrimidine dimer lesion [DNA photolyase] (Mus musculus) PubMed

 1230.

genetic analysis of glnN promoter region; non-canonical NtcA-binding motif is responsible for NtcA-dependent, nitrogen-responsive regulation of glnN; P(II) signalling protein has opposing effects on NtcA-dependent glnN expression [glnN] (Mus musculus) PubMed

 1231.

SipA identified as a sensor histidine kinase non-bleaching sensor (NblS) interacting protein, at the ATP binding domain. [SipA, Nbls] (Mus musculus) PubMed

 1232.

PsR domain of CikA negatively regulates histidine protein kinase activity in vivo and also serves as an interaction module to dock CikA at a specific subcellular location. [CikA] (Mus musculus) PubMed

 1233.

Results suggest the involvement of DnaK3 in the translational process on the surface of the thylakoid membrane [DnaK3] (Mus musculus) PubMed

 1234.

Pex from cyanobacterium Synechococcus elongatus PCC 7942 has an (alpha+beta) structure with a winged-helix motif and functions as a dimer; the subunit arrangement in the dimer is unique. Pex is a DNA-binding transcription factor[pex protein] (Mus musculus) PubMed

 1235.

results suggest that DnaK2 and DnaJ2 are involved in RNA degradation through interaction with RNase E [DnaJ2 & DnaK2] (Mus musculus) PubMed

 1236.

in the stress responses of three dnaK homologues (dnaK1, dnaK2, and dnaK3), only the dnaK2 gene was induced [nak1,dnak2, dnak3] (Mus musculus) PubMed

 1237.

PratA is a periplasmic tetratricopeptide repeat protein involved in biogenesis of photosystem II in Synechocystis sp. PCC 6803 (Mus musculus) PubMed

 1238.

Under salt stress, hspA, groEL2 and dnaK2 were transcriptionally induced and greatly stabilized, indicating a transcriptional and post-transcriptional mechanism of acclimation to salt stress involving these heat-shock genes. [hspA],[groEL2],[dnaK2] (Mus musculus) PubMed

 1239.

PixJ1 protein was overexpressed as a fusion with a poly-histidine tag (His-PixJ1); His-PixJ1 showed novel photoreversible conversion between a blue light-absorbing(Pb, lambdaAmax=425-435 nm) and a green light-absorbing form (Pg, lambdaAmax=535 nm) [PixJ1] (Mus musculus) PubMed

 1240.

menB and rubA have roles in expression of FX, FA, and FB and plastoquinone or exchanged 9,10-anthraquinone [rubA] (Mus musculus) PubMed

 1241.

results suggest that aquaporin-mediated shrinkage of the Synechocystis cells plays an important role in changes of gene expression in response to hyperosmotic stress [Aqpz] (Mus musculus) PubMed

 1242.

Hik8 plays an important role in glucose metabolism and is necessary for heterotrophic growth. [Hik8] (Mus musculus) PubMed

 1243.

structure analyzed by x-ray diffraction [apocarotenoid-15,15'-oxygenase] (Mus musculus) PubMed

 1244.

results indicate that SigE functions in the transcriptional activation of sugar catabolic pathways in Synechocystis sp. PCC 6803 [SigE]. (Mus musculus) PubMed

 1245.

FesM, encoding a novel membrane iron-sulfur protein, is essential to cyclic electron flow in the cyanobacterium Synechococcus. (fesM protein) (Mus musculus) PubMed

 1246.

the environmental regulation of the Synechocystis sp. PCC 6803 deg genes at the level of transcription and protein structures [degP, depQ, degS] (Mus musculus) PubMed

 1247.

PamA has a role in the transcript control of genes for nitrogen and sugar metabolism in Synechocystis sp. PCC 6803 (Mus musculus) PubMed

 1248.

Signal transduction protein P(II) is dephosphorylated in Synechocystis sp. strain PCC 6803 by protein phosphatase PphA [PPHA] (Mus musculus) PubMed

 1249.

role of cytochrome c6 in reaction mechanism of photosystem I reduction [cytochrome c6] (Mus musculus) PubMed

 1250.

characterization and crystal structure of Synechocystis arogenate dehydrogenase (Mus musculus) PubMed

 1251.

identification of the gene for monoglucosyldiacylglycerol (MGlcDG) synthase, which catalyzes the first step of galactolipid synthesis in cyanobacteria[MGlcDG synthase] (Mus musculus) PubMed

 1252.

The crystal structure of the substrate-free form of PcyA from Synechocystis sp. PCC 6803 at 2.5 A resolution was determined.[PcyA] (Mus musculus) PubMed

 1253.

Cytochrome c3 and [NiFe]-hydrogenase are linked to photosystem I to photoproduce hydrogn. [photosystem I] (Mus musculus) PubMed

 1254.

Overall, we determined that transcription of the heat-shock genes are regulated to various degrees by SigB, SigE and HrcA. [SigB, SigE] (Mus musculus) PubMed

 1255.

PfsR has a critical role in regulation of iron homeostasis and stress response (Mus musculus) PubMed

 1256.

SpkA regulates the expression of putative pilA9-pilA10-pilA11-slr2018, pilA5-pilA6, and pilA1-pilA2 operons and is essential for the formation of thick pili.[SpkA] (Mus musculus) PubMed

 1257.

Ala69Ser substitution on Synechocystis sp. PCC 6803 hemoglobin resulted in minor structural perturbations, but the response of the holoprotein to temperature-, urea-, and acid-induced denaturation was measurably affected. [Hemoglobin] (Mus musculus) PubMed

 1258.

We find that cya1 and sycrp1 mutants are motile and phototactic but are impaired in one particular phase of phototaxis in comparison with wild-type Synechocystis sp. (Mus musculus) PubMed

 1259.

PedR (Ssl0564) senses the activity of photosynthetic electron transport to achieve the photon flux density-dependent transcriptional regulation (Mus musculus) PubMed

 1260.

Nuclear magnetic resonance (NMR) was used to map the binding sites on Synechocystis ferredoxin for ferredoxin-thioredoxin reductase. (Mus musculus) PubMed

 1261.

FutA2 contributes to metal partitioning in the periplasm by sequestering ferric iron (Fe(III)), which limits aberrant Fe(III) associations with vital binding sites for other metals, including copper. (Mus musculus) PubMed

 1262.

Results demonstrate that dspA and nblR-like do not exert a major control of phycobilisomes degradation in Synechocystis sp. PCC 6803. [dspA, NblR-like proteins} (Mus musculus) PubMed

 1263.

This study identified the factor that binds the HLR1 upstream of the HL-inducible hliB gene in the cyanobacterium Synechocystis PCC 6803 as the RpaB (Slr0947) response regulator.[RpaB hliB proteins] (Mus musculus) PubMed

 1264.

REsults describe a beta-1,4-glucanase-like protein (SsGlc) from Synechocystis PCC6803 and suggest that SsGlc functions in salt stress tolerance. (Mus musculus) PubMed

 1265.

SigD and SigE interfere with each other's expression. (SigD) (SigE) (Mus musculus) PubMed

 1266.

Expression of DnaK3 appears also to be as essential as expression of DnaK2, whereas the dnaK1 gene was deleted without resulting in any distorted phenotype.[DnaK1, DnaK2, DnaK3] (Mus musculus) PubMed

 1267.

mutations into SphR show that Gly-225 and Trp-236, which are both conserved in SphR from cyanobacteria, are essential for activation of the Pho regulon under phosphate-limiting conditions.[SphR] (Mus musculus) PubMed

 1268.

We analyse the mechanism underlying (GS)glutamine synthetase I reactivation and find that this process involves IF7 and IF17 proteolytic degradation. [GSI, IF7, I17] (Mus musculus) PubMed

 1269.

Unique to these ABC zinc transporters, ZnuA has a highly charged and mobile loop that protrudes from the protein in the vicinity of the metal binding site that we had suggested might facilitate zinc acquisition.zua, synechocystis (Mus musculus) PubMed

 1270.

The Fe/S protein SufR thus functions both as a transcriptional repressor of the sufBCDS operon and as an autoregulator of sufR.[sufR, sufBCDS] (Mus musculus) PubMed

 1271.

This transcription factor, an AbrB-like protein functions as a regulator of hox gene expression. [AbrB] (Mus musculus) PubMed

 1272.

There is a reduced level of ferric FutA2 in the periplasm of the DeltafutA1 mutant providing an explanation for its severe iron-uptake phenotype.[FutA2] (Mus musculus) PubMed

 1273.

study reports three-dimensional structures of two proteins of previously unknown function, CcmL and OrfA (or CsoS4A), from the two known classes of carboxysomes, at resolutions of 2.4 and 2.15 angstroms [OrfA or CsoS4A] (Mus musculus) PubMed

 1274.

Thus, CpcM is the methyltransferase that modifies the amide nitrogen of Asn71/72 of CpcB, ApcB, and ApcF. (Mus musculus) PubMed

 1275.

The loss of phycocyanin-lyase function causes pleiotropic effects in Synechocystis sp. PCC 6803.[Phycocyanin lyase] (Mus musculus) PubMed

 1276.

The hybrid kinase Sll0043 regulates phototaxis by suppressing the expression of pilA1 biosynthesis and pilT2. [pilA1] (Mus musculus) PubMed

 1277.

CcaS phosphorylates CcaR under green light and induces expression of cpcG2, leading to accumulation of CpcG2-phycobilisome as a chromatic acclimation system[CcaS] (Mus musculus) PubMed

 1278.

Mutation prqRL17Q changes the specificity of the PrqR repressor protein and thereby affects the regulation of phototaxis at the level of photoperception and signal transduction in cells. (Mus musculus) PubMed

 1279.

Psb30 is required for the efficient function of photosystem II complexes, particularly under high irradiance conditions. [Psb30] (Mus musculus) PubMed

 1280.

PetC1, PetC2 and PetC3 are Rieske iron-sulfur proteins. PetC1 and PetC2 are Tat substrates and are located in the thylakoid membrane. PetC3 is primarily located in the plasma membrane. [PetC1, PetC2, PetC3] (Mus musculus) PubMed

 1281.

substrate specificity stems from faster turnover of GTP, rather than different affinities for GTP and ATP, implying that the specificity-determining interactions are established after the binding step[guanylyl cyclase Cya2] (Mus musculus) PubMed

 1282.

RpaB acts as a transcriptional activator for PSI genes. [RpaB] (Mus musculus) PubMed

 1283.

Enzymatic and spectroscopic properties of Synechocystis cytochrome bd, were characterized.[Cytochrome bd] (Mus musculus) PubMed

 1284.

These results suggested that in contrast to a previous report, the loss of photosynthetic activity may not have been due to the loss of thylakoid membranes, but may have been caused more directly by the loss of Vipp1 in Synechocystis 6803.[Vipp1] (Mus musculus) PubMed

 1285.

The authors show that in the absence of MrgA, which is known to be involved in the storage or mobilization of iron, cells can be more easily damaged by exogenous oxidative and light stress.[mrgA] (Mus musculus) PubMed

 1286.

The light-harvesting system of the sigBD double mutant does not acclimate normally to higher light intensity. [SigB] (Mus musculus) PubMed

 1287.

The presence of the carotenoid carbonyl group that distinguishes echinenone and hydroxyechinenone from zeaxanthin is essential for the OCP activity.[OCP] (Mus musculus) PubMed

 1288.

role of NhaS3 in the maintenance of ion homeostasis of H+, Na+, and K+ in supporting the conversion of photosynthetic products and in the supply of energy in the dark[NHAS3] (Mus musculus) PubMed

 1289.

The expression of AdhA, an alcohol dehydrogenase, is enhanced upon the exposure of cells to different environmental stresses. AdhA induction is dependent on the Hik34-Rre1 two-component system. New Gene: AdhA (Mus musculus) PubMed

 1290.

The Arg7Leu mutation on the alpha-subunit of cyt b559 alters the interaction between the allophycocyanin core complex and PSII reaction centers.[cyt b559] (Mus musculus) PubMed

 1291.

Results identify several amino acid residues that are essential for monoglucosyldiacylglycerol synthase activity at both normal growth temperature and high temperature. (Mus musculus) PubMed

 1292.

Data found that both SepF and Ftn6 interact physically with FtsZ and that , but not Ftn6, stimulates the formation and/or stability of FtsZ polymers in vitro.[SepF] (Mus musculus) PubMed

 1293.

The electrostatic potential of the surface generated by Psb27 amphipathic helices shows a dipolar distribution which fits perfectly into the major PsbO binding site on the photosystem II complex. [Psb27] (Mus musculus) PubMed

 1294.

The position of conserved residues on the Psb27 surface suggests conserved functional roles for distinct interconnected features encompassing a P-phi-P loop, a polar patch spanning helices alpha3 and alpha4, and the amino-terminal sequence. [Psb27] (Mus musculus) PubMed

 1295.

ZipN interacts with itself and the self-interacting protein Cdv3, and is a central player of divisome assembly in cyanobacteria. [ZipN] (Mus musculus) PubMed

 1296.

crystal structure of the full-length HMG-CoA synthase was determined at 2.0-A resolution, representing the first structure of an HMG-CoA synthase from any organism [HMG-CoA synthase strain WCUH29] (Mus musculus) PubMed

 1297.

The roles of HtrA-like serine surface proteases, htrA1 and htrA2, in the thermal stress response and and processing and/or degradation of extracellular proteins was investigated (HtrA1 and HtrA2). (Mus musculus) PubMed

 1298.

Staphylococcal accessory regulator A (sarA) may play a role in the intrinsic multidrug resistance mechanism of S. aureus (sarA). (Mus musculus) PubMed

 1299.

crystal structure of peptide deformylase in complex with actinonin, a naturally occurring antibacterial agent [peptide deformylase] (Mus musculus) PubMed

 1300.

Results describe the structures of Aspergillus nidulans and Staphylococcus aureus dehydroquinate synthase (AnDHQS and SaDHQS), and compare ligand-induced conformational changes and mechanisms of domain closure between fungal and bacterial enzymes. (Mus musculus) PubMed

 1301.

FhuD1 is a ferric hydroxamate-binding lipoprotein in Staphylococcus aureus (Mus musculus) PubMed

 1302.

Bap binds Ca2+ with low affinity and that Ca2+ binding renders the protein noncompetent for biofilm formation and for intercellular adhesion [Bap (biofilm-associated protein)]by Staphylococci isolated from chronic mastitis [Bap strain V329] (Mus musculus) PubMed

 1303.

AgrA binds to RNAIII and functions as a response regulator with recognition sites in the promoter regions of RNAIII and the agr locus [AgrA strain DB] (Mus musculus) PubMed

 1304.

results indicate that spa expression is controlled by DNA supercoiling and suggest that the Arl sytem is involved in the control of spa expression by DNA supercoiling [spa, ArlS, ArlR] (Mus musculus) PubMed

 1305.

a key finding of this study is that Staphylococcus aureus pantothenate kinase (CoaA) differs from all described previously pantothenate kinases in that it is refractory to feedback inhibition by CoA and/or its thioesters [CoaA] (Mus musculus) PubMed

 1306.

MgrA overexpression and promoter region mutations result in a reduction in NorA expression [mgrA AND norA] (Mus musculus) PubMed

 1307.

Detection of the antiseptic- and disinfectant-resistance genes qacA and qacB in methicillin-resistant S. aureus isolated during MRSA surveillance in a single hospital.[qacA, qacB] (Mus musculus) PubMed

 1308.

staphostatin B structure compared to standard mechanism serine protease inhibitors [staphostatin B] (Mus musculus) PubMed

 1309.

PBP2 recruited to the division site by binding to its transpeptidation substrate, which is localized at that place [PBP2, strain RN4220] (Mus musculus) PubMed

 1310.

spa repression occurs not only at the transcriptional level but also by RNAIII-mediated inhibition of translation and degradation of the stable spa mRNA by the double-strand-specific endoribonuclease III (RNase III) [spa & endoribonuclease III & RNAIII] (Mus musculus) PubMed

 1311.

The coordination of pbp2 with pbp4 and pbp2a (in MeSH) in ceftizoxime resistance and cell wall cross-linking.[pbp2a] (Mus musculus) PubMed

 1312.

studies here have defined the nature of interaction of mgrA with other regulators such as agr, sarS, and sarT and its role in regulating hla and spa transcription within the virulence regulatory network of S. aureus[MgrA] (Mus musculus) PubMed

 1313.

PIA expression is dependent on the genetic background of the strain as well as on strong inducing conditions in device-related infection model, such as those dominating in vivo. [PIA] (Mus musculus) PubMed

 1314.

The regulatory role of MgrA in the expression of NorB and Tet38, two drug efflux pumps in S. aureus [MgrA, NorB, Tet38] (Mus musculus) PubMed

 1315.

demonstrated that a putative glycoprotease (Gcp) is required for staphylococcal growth [gcp] (Mus musculus) PubMed

 1316.

data indicates that ClpYQ plays only a secondary role in the degradation of non-native proteins in S. aureus [ClpY, ClpQ] (Mus musculus) PubMed

 1317.

results show that Pls is a virulence factor for septic arthritis and sepsis [Pls] (Mus musculus) PubMed

 1318.

cloning and identification of the gene, azo1, encoding a novel aerobic tetrameric FMN-dependent azoreductase [Azo1] (Mus musculus) PubMed

 1319.

results indicate that cidC is involved in the generation of acetic acid that contributes to the cell death and lysis that occurs in high-glucose stationary phase cultures [cidC, pyruvate oxidase] (Mus musculus) PubMed

 1320.

identification of sae as an important regulator of the staphylococcal adhesins Eap and Emp, which is capable of modulating their expression under different environmental conditions [sae, Eap, Emp] (Mus musculus) PubMed

 1321.

Structural model and substrate specificity of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus (FAbH). (Mus musculus) PubMed

 1322.

SEG and SEI co-express, differently interact with MHC class II, stimulate different subsets of T-cells, which indicate complementary superantigenic activity and suggest an important advantage to staphylococcal strains in producing them both.(SEG)(SEI) (Mus musculus) PubMed

 1323.

ClfA promotes platelet activation in fibrinogen dependent and independent pathways with the latter requiring IGG and complement deposition [ClfA, clumping factor A] (Mus musculus) PubMed

 1324.

the cidR gene product functions as a transcriptional activator of cidABC transcription in response to acetic acid accumulation in the growth medium [CidR] (Mus musculus) PubMed

 1325.

strains carrying seb and selp produced SEB but not SElP, suggesting the inactivation of the selp locus in S. aureus strains with a particular se gene constitution (SElP = staphylococcal enterotoxin-like toxin P) (Mus musculus) PubMed

 1326.

ClfA(221-550) is a fibrinogen-binding segment of Staphylococcus aureus clumping factor A that disrupts fibrinogen function [from isolate 30326] (Mus musculus) PubMed

 1327.

role of penicillin Binding protein 2a in oxacillin resistance, and discovery of functionally impaired form of PBP2a with a novel amino acid substitution [PBP2a] (Mus musculus) PubMed

 1328.

roles in copper homeostasis and oxidative stress response [mco, multicopper oxidase] (Mus musculus) PubMed

 1329.

TRAP is a master regulator of staphylococcal pathogenesis.(TRAP) (Mus musculus) PubMed

 1330.

DsbA is a membrane localised lipoprotein, supporting a role in disulfide bond formation. The persistence of the protein throughout the growth cycle despite its predominant transcription during exponential growth phase suggested a long half-life[DsbA] (Mus musculus) PubMed

 1331.

role of the N terminus in the assembly of alpha-hemolysin [alpha-hemolysin] (Mus musculus) PubMed

 1332.

purification and characterization of a 32 kDa N-acetylmuramyl-L-alanine amidase designated Sle1; findings suggest Sle1 is involved in cell separation [Sle1] (Mus musculus) PubMed

 1333.

results demonstrated that the YhcSR regulatory system is indispensable for S. aureus growth in culture [YhcS, YhcR] (Mus musculus) PubMed

 1334.

crystal structure in three crystal forms at different pH values [LytM] (Mus musculus) PubMed

 1335.

dltA and mprF mutations in Staphylococcus aureus increased in vitro susceptibility to platelet microbicidal protein 1 and significantly attenuated virulence. (dltA)(mprF) (Mus musculus) PubMed

 1336.

To assess the roles of ClpX and ClpP within the sar/agr regulatory network, deletions in clpX and clpP were combined with mutations in these genes. (ClpX) (ClpP) (Mus musculus) PubMed

 1337.

SigB regulates transcription of virulence factors in SCVs (Staphylococus aureus small-colony variant) from cystic fibrosis patients [SigB] (Mus musculus) PubMed

 1338.

Data suggest that the fibrinogen/fibronectin-binding proteins FnBPA and FnBPB are major platelet-activating factors on the surface of S. aureus, and act through FcgammaRIIa and GPIIb/IIIa [FnBPA, FnBPB]. (Mus musculus) PubMed

 1339.

Data describe the contribution that individual metal ligands of the alpha5 sensing site of S. aureus CzrA make to metal ion binding affinity, coordination geometry, and allosteric negative regulation of DNA operator/promoter region binding (Mus musculus) PubMed

 1340.

cocrystal structure reveals the basis for both sequence and structure specificity in the interactions of TadA with RNA, and it additionally provides insight into the active site architecture that promotes efficient hydrolytic deamination [TadA] (Mus musculus) PubMed

 1341.

Small colony variants (SCVs) of Staphylococcus aureus as well as hemB- and menD-deficient mutants of S. aureus are greatly reduced in virulence in the C. elegans infection model. [HemB, MenD] (Mus musculus) PubMed

 1342.

first report of a temperature-sensitive dnaA mutant in S. aureus, and the results show that DnaA is required for the initiation of chromosomal replication and for the regulation of synchrony in the bacterial cells [DnaA] (Mus musculus) PubMed

 1343.

2.6 A-resolution x-ray crystal structure of the dimeric winged helix SarA protein was reported. (Mus musculus) PubMed

 1344.

findings support the conclusion that FhuC functions with FhuB, FhuG, and FhuD1 or FhuD2 to transport iron(III)-hydroxamates and is the "genetically unlinked" ABC-ATPase that functions with SirA, SirB, and SirC to transport iron(III)-staphylobactin [FhuC] (Mus musculus) PubMed

 1345.

Derepression of PerR by HOCl is dependent on the level of SOD and protects exponentially arrested cells against HOCl stress.[PerR, SOD] (Mus musculus) PubMed

 1346.

in spite of the preferential location of the binding epitopes within triple helical regions in some collagens there is a striking specificity of Eap binding to different collagen types [Eap] (Mus musculus) PubMed

 1347.

Complementation experiments with sigB on a plasmid reduced expression of proteases and alpha-hemolysin dramatically, indicating that the high production of these exoproteins was associated with sigmaB deficiency. [SigB] (Mus musculus) PubMed

 1348.

role of the conserved Glu100 of S. aureus MGT (equivalent to the proposed catalytic Glu233 of E. coli PBP1b) by site-directed mutagenesis [monofunctional glycosyltransferase] (Mus musculus) PubMed

 1349.

observations suggest that the role of murF exceeds its primary function in peptidoglycan biosynthesis and may also be involved in the control of cell division (Mus musculus) PubMed

 1350.

The role of SarA in the regulation of virulence factor expression in S. aureus is reported.[SarA] (Mus musculus) PubMed

 1351.

The dimeric repressor MecI regulates the mecA gene that encodes the penicillin-binding protein PBP-2a in methicillin-resistant Staphylococcus aureus(MecI) (Mus musculus) PubMed

 1352.

MoaA binds 5'-GTP with high affinity and interacts through its C-terminal [4Fe-4S] cluster with the guanine N1 and N2 atoms, in a yet uncharacterized binding mode [MoaA] (Mus musculus) PubMed

 1353.

ClfA inhibited phagocytosis in the absence of fibrinogen, and showed enhanced inhibition in the presence of fibrinogen. (Mus musculus) PubMed

 1354.

Data show that SarR (a member of the SarA protein family) in part regulates agr expression by direct binding to the agr intergenic promoter region as determined by gel shift and DNase I footprinting assays [SarR]. (Mus musculus) PubMed

 1355.

results suggest that LukM/F'-PV may constitute a particular virulence attribute of mastitis-causing S. aureus strains [LukM, LukF'-PV] (Mus musculus) PubMed

 1356.

Apart from an apparent direct positive effect of mgrA on sspA & aur transcription, these genes were mainly controlled through repression by sarA & rot, which seemed to occur via binding of SarA & Rot to the aur & sspA promoters, respectively[sarA, rot] (Mus musculus) PubMed

 1357.

assembly of LukS and LukF into the pore-complex occurs in lipid rafts in human polymorphonuclear leukocytes and that LukF can bind to LukS, which had already bound to lipid rafts, to assemble into hetero-oligomers [LukS and LukF] (Mus musculus) PubMed

 1358.

it is concluded that expression of the Cfr rRNA methyltransferase confers a PhLOPSA resistance phenotype (resistance to five chemically distinct classes of antimicrobials: Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A [Cfr] (Mus musculus) PubMed

 1359.

Our results indicate that activation of the SaeRS system may be required for S. aureus to adhere to and invade epithelial cells. [SaeR, SaeS] (Mus musculus) PubMed

 1360.

examined the potential of the YjeQ protein as a virulence determinant [YjeQ] (Mus musculus) PubMed

 1361.

role in Staphylococcus aureus fitness and resistance to antioxidants and neutrophil killing [staphyloxanthin] (Mus musculus) PubMed

 1362.

RNAIII regulates the synthesis of Rot, by blocking its translation; it is proposed that the RNAIII-rot mRNA interaction plays a key role in agr regulation of staphylococcal virulence [rot] (Mus musculus) PubMed

 1363.

findings show that the vraS/vraR regulatory system plays a crucial role in allowing MRSA to respond to beta-lactams by regulation of a gene target other than the known effectors of methicillin resistance [VraS, VraR] (Mus musculus) PubMed

 1364.

3.0 A crystal structure of a bacterial ABC transporter (Sav1866) from Staphylococcus aureus [Sav1866] (Mus musculus) PubMed

 1365.

The study reveals that in Staphylococcus aureus, MgrA adopts a similar mechanism but uses it to globally regulate different defensive pathways. (Mus musculus) PubMed

 1366.

crystal structure of S. aureus CoADR has been solved using multiwavelength anomalous dispersion data and refined at a resolution of 1.54 A [coenzyme A-disulfide reductase] (Mus musculus) PubMed

 1367.

cells surviving an attack by alpha toxin can be induced to proliferate via recruitment of an EGFR-dependent signalling pathway (alpha-toxin) (Mus musculus) PubMed

 1368.

results indicate that exported alpha-toxin inhibits the adhesion and internalization of S. aureus by interfering with integrin-mediated pathogen-host cell interactions (S. aureus WCUH29 alpha-tox; hla gene) (Mus musculus) PubMed

 1369.

results indicate that, in contrast to NCTC 8325 derivatives, agr plays a limited role in overall regulation of gene expression in UAMS-1, when compared with sarA [agr, sarA] (Mus musculus) PubMed

 1370.

Collectively, the results suggest that arlR positively regulates capsule production at the transcriptional level primarily through an mgrA-dependent pathway.[arlR, mgrA] (Mus musculus) PubMed

 1371.

The structures of unliganded monophosphate kinase (GMK) and GMK complexed with GMP at 1.9 A resolution (GMK). (Mus musculus) PubMed

 1372.

S. aureus FnBPA produces attachment sites that promote bacterial movements but subvert actin- and Rab5 reorganization during invasion.[FnBPA] (Mus musculus) PubMed

 1373.

IsdB-mediated scavenging of iron from hemoglobin represents an important virulence strategy for S. aureus replication in host tissues and for the establishment of persistent staphylococcal infections. [IsdB] (Mus musculus) PubMed

 1374.

Regulation of Staphylococcus aureus alpha-toxin gene (hla) expression by agr, sarA, and sae [hla] (Mus musculus) PubMed

 1375.

SrrAB regulates RNAIII, tst, spa, icaR, and icaA in a clinical isolate of S. aureus, MN8 (SrrA and SrrB). (Mus musculus) PubMed

 1376.

Three genes in glycolipid synthesis and lipotheichoic acid anchoring were identified: alpha-phosphoglucomutase (PgcA) and UTP:alpha-glucose 1-phosphate uridyltransferase (GtaB)and LtaA (lipoteichoic acid protein A), [PgcA, GtaB, LtaA] (Mus musculus) PubMed

 1377.

findings show that Panton-Valentine leukocidin is sufficient to cause pneumonia & that the expression of this leukotoxin induces global changes in transcriptional levels of genes encoding secreted & cell wall-anchored staphylococcal proteins [LukS,LukF] (Mus musculus) PubMed

 1378.

The study suggests that Fibronectin binding protein A (FnBPA) binds to fibrinogen and elastin in a similar manner, amino acid sequence divergence of 26.5% occurred between the A domains of FnBPA from strains 8325-4 and P1. [FnBPA protein] (Mus musculus) PubMed

 1379.

crystal structure of Sav1866 in complex with adenosine-5'-(beta,gamma-imido)triphosphate (AMP-PNP) at 3.4A resolution and comparison with the previously determined structure of Sav1866 with bound ADP (Mus musculus) PubMed

 1380.

results support the previous report that isaA expression is regulated by YycF, and also suggest that IsaA is probably involved in bacterial proliferation by residing on the cell wall [IsaA] (Mus musculus) PubMed

 1381.

menstrual toxic shock syndrome patients may be incapable of generating TSST-1 neutralizing antibodies (Mus musculus) PubMed

 1382.

2.8 angstrom structure of penicillin binding protein 2, a bifunctional cell-wall cross-linking enzyme, including its transpeptidase and GT domains, both unliganded and complexed with the substrate analog moenomycin [PBP2] (Mus musculus) PubMed

 1383.

Interaction of alpha-toxin with alpha5beta1-integrin and overproduction of TNF-alpha may contribute to destruction of epithelial cells during S. aureus infection. (Mus musculus) PubMed

 1384.

The active site proline in thioredoxin determines the driving potential for substrate reduction (Sa_Trx) (Mus musculus) PubMed

 1385.

Study shows that protein A, the ligand of immunoglobulin, is unevenly distributed over the staphylococcal surface; upon removal with trypsin, newly synthesized polypeptide is deposited at two to four discrete foci. [protein A] (Mus musculus) PubMed

 1386.

Transient nature of MupA polymorphism accounts for transient loss of high level mupirocin resistance. [MupA] (Mus musculus) PubMed

 1387.

The data indicate that the expression of rot transcription is significantly repressed only by SarA. [rot] (Mus musculus) PubMed

 1388.

the antithrombotic effect of ClfA221-550 may result from the blockade of fibrinogen gamma chain C-terminal functions, in mediating platelet aggregation and fibrin clot formation.[Clumping factor A, Staphylococcus aureus} (Mus musculus) PubMed

 1389.

GraRS, the 2 component regulatory system regulates vancomycin intermediate resistance phenotype by interactions with VraFG ABC transporter. [GraR, GraS] (Mus musculus) PubMed

 1390.

The absence of Bap correlated with increased adherence to fibrinogen and fibronectin.[Bap protein] (Mus musculus) PubMed

 1391.

Constructed tatC-deficient mutants from distinct parent strains showed the same patterns of exoproteins compared with those of parent strains; it seems that the Tat pathway does not play a major role in the secretion system of S. aureus.[tatC] (Mus musculus) PubMed

 1392.

Linezolid resistance in a methicillin-resistant Staphylococcus aureus hospital strain from Colombia is determined by the cfr gene whose product, Cfr methyltransferase, modifies adenosine at position 2503 in 23S rRNA in the large ribosomal subunit. [Cfr] (Mus musculus) PubMed

 1393.

NMR solution structure of MecI complexed to a operator sequence provides insights for the repression and induction mechanisms of bacterial resistance to beta-lactams (MecI). (Mus musculus) PubMed

 1394.

Crystal structures of Mevalonate diphosphate decarboxylase (MDD) from T. brucei (TbMDD, at 1.8 A resolution) and S. aureus (SaMDD, each diffracting to 2.3 A resolution) have been determined[mevalonate diphosphate decarboxylase ] (Mus musculus) PubMed

 1395.

the monomer orthorhombic Sau3AI/E64A crystal is in space group C2221 with unit cell parameters (69.44, 197.60, 191.46, 90, 90, 90) and contains two molecules in one asymmetric unit[Sau3AI endonuclease] (Mus musculus) PubMed

 1396.

Data supports a catalytic mechanism in which the reduced flavin coenzyme mediates a single electron transfer to and from the IPP substrate during catalysis by type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IDI-2). (Mus musculus) PubMed

 1397.

Cloning and purification of the two known S. aureus signal peptidases, SpsA and SpsB, demonstrated that only SpsB catalysed type I signal peptidase activity in vitro. (Mus musculus) PubMed

 1398.

The ypfP gene responsible for biosynthesis of a glycolipid found in LTA was deleted in Staphylococcus aureus SA113, causing 87% reduction of the LTA content.[ypfP, autolysin] (Mus musculus) PubMed

 1399.

An isaA sceD mutant is attenuated for virulence, while SceD is essential for nasal colonization in cotton rats, thus demonstrating the importance of cell wall dynamics in host-pathogen interactions.[isaA, sceD] (Mus musculus) PubMed

 1400.

results demonstrate that SrrAB is a major activator of ica expression and polysaccharide intercellular adhesin production in anaerobic environments, where it contributes to the protection of S. aureus against non-oxidative defence mechanisms [SrrA, SrrB] (Mus musculus) PubMed

 1401.

As the length of the ClfA repeat region increased, binding of acapsular S. aureus to fibrinogen-coated microtiter plates was enhanced; by contrast, encapsulated S. aureus expressing the full-length ClfA were poorly adherent.[ClfA] (Mus musculus) PubMed

 1402.

This study showed that WalKR positively controls autolytic activity.[WalK; WalkR] (Mus musculus) PubMed

 1403.

the three-dimensional structure of the complex of SSL7 with Fc of human IgA1 at 3.2 A resolution (SSL7). (Mus musculus) PubMed

 1404.

findings show that S aureus products have various effects on mucosal tissues: surface protein A induces mast cell degranulation, whereas enterotoxin B induces the release of cytokines, with a T(H)2-skewed pattern in nasal polyps.[SEB, protein A] (Mus musculus) PubMed

 1405.

Affinity purification of proteins binding to the rot promoter fragment, followed by N-terminal protein sequencing, identified the SarA and SarR proteins.[SarA and SarR in strain GP269] (Mus musculus) PubMed

 1406.

The effects of ceramide incorporation in supported bilayers prepared from ternary lipid mixtures which have small nanoscale domains have been examined using atomic force and fluorescence microscopy.[SMase] (Mus musculus) PubMed

 1407.

MenB consists of 2 subunits & a crystallographic threefold axis of symmetry generates a hexamer. MenB displays crotonase-family fold with distinct N- & C-terminal domains & a flexible segment of structure around the active site.[MenB] (Mus musculus) PubMed

 1408.

SaDsbA crystals diffract to a resolution limit of 2.1 A and belong to the hexagonal space group P6(5) or P6(1), with unit-cell parameters a = b = 72.1, c = 92.1 A and one molecule in the asymmetric unit (64% solvent content)[DsbA] (Mus musculus) PubMed

 1409.

The expression of copA and copZ was inducible by copper and to some extent by ferric and lead ions. The cysteine residues in the CXXC metal-binding motif in CopA are involved in copper binding and play an important role in copper transport. [CopA, CopZ] (Mus musculus) PubMed

 1410.

fibrinogen and IgG binding to ClfA is essential for aggregate formation under arterial shear conditions and may explain why S. aureus is the major cause of infective endocarditis [C1fA] (Mus musculus) PubMed

 1411.

This strain is the first clinical isolate of MRSA for which the genetic base for high-level resistance has been clarified. It is connected to a LytH mutation caused by IS1182 insertion. [LytH] (Mus musculus) PubMed

 1412.

These results suggest that His343 of S. aureus MurC is essential for high-affinity binding to L-alanine both in vitro and in vivo and provide experimental evidence supporting the structural information of MurC ligase.[MurC] (Mus musculus) PubMed

 1413.

The crystal structures of non-thiocarboxylated MPT synthase from Staphylococcus aureus in its apo form and in complex with precursor Z, is presented.[MPT synthase] (Mus musculus) PubMed

 1414.

Collectively, the data implicated the importance of sae in the rot-mediated repression of hla in S. aureus. [rot, hla in strain RN4220] (Mus musculus) PubMed

 1415.

Mutants resulting from an rplB-to-rplV gene conversion-like event is specific to selection of telithromycin resistance in staphylococcus aureus. [rplB, rplV] (Mus musculus) PubMed

 1416.

In Staphylococcus aureus V8 strain, data showed that glutamyl endopeptidase I (GluV8) Ser237 was essential for proteolytic activity, and Val69 was indispensable for the cleavage by thermolysin and was involved in the proteolytic reaction itself [GluV8] (Mus musculus) PubMed

 1417.

The spontaneous reversible unfolding and refolding of staphylococcal nuclease under native conditions was studied by a kinetic native-state hydrogen exchange (HX) method.[SNase] (Mus musculus) PubMed

 1418.

This study shows that this variation of biofilm formation in S. aureus is deduced by the role of sigB, not agr and sarA. [SigB] (Mus musculus) PubMed

 1419.

determineation of the crystal structures of S. aureus dehydrosqualene synthase (CrtM) at 1.58 angstrom resolution; structural similarity to human squalene synthase found [dehydrosqualene synthase] (Mus musculus) PubMed

 1420.

The crystal structures at 2.8-A resolution of full-length PC from Staphylococcus aureus and the C-terminal region (missing only the BC domain) of human PC, is reported.[Pyruvate carboxylase] (Mus musculus) PubMed

 1421.

The signal transduction mechanism of the VraSR system, is reported.[VraR, VraS] (Mus musculus) PubMed

 1422.

triclosan, 5-ethyl-2-phenoxyphenol (EPP), and 5-chloro-2-phenoxyphenol (CPP) are all nanomolar slow-onset inhibitors of saFabI[FabI] (Mus musculus) PubMed

 1423.

Deletion of ccpA, coding for the catabolite control protein A (CcpA), abolished the capacity of SA113 to form a biofilm under static and flow conditions, while still allowing primary attachment to polystyrene surfaces.[CcpA in strain SA113] (Mus musculus) PubMed

 1424.

data identify a novel S. aureus biofilm phenotype promoted by FnBPA and FnBPB which is apparently independent of the known ligand-binding activities of these proteins[FnBPA, FnBPB] (Mus musculus) PubMed

 1425.

model contradicts the previously proposed mechanism of binding predicted by the x-ray crystal structure of SrtA[ sortase A] (Mus musculus) PubMed

 1426.

Two mutations were identified in katA from S. aureus UCN61,a methicillin-susceptible catalase-negative strain isolated from an arterial leg ulcer, including one leading to a substitution of key histidine 58 by a tyrosine. [katA] (Mus musculus) PubMed

 1427.

Results describe SplB protease catalytic activity and reveal that the enzyme possesses exquisite specificity and only cleaves efficiently after the sequence Trp-Glu-Leu-Gln. (Mus musculus) PubMed

 1428.

Nuclease A [nuc1] and thermonuclease [nuc2] are two thermostable nucleases, coesiting and encoded by two different genes. [nuc1, nuc2] (Mus musculus) PubMed

 1429.

findings show that graRS deletion considerably alters bacterial surface charge, increases susceptibility to killing by human neutrophils or the defense peptide LL-37 & attenuates virulence of S. aureus in a mouse infection model [GraR, GraS] (Mus musculus) PubMed

 1430.

The femA regulating gene probably lies in the 250 bp upstream sequence in methicillin-resistant Staphylococcus aureus and high-level expression is essential for high-level methicillin resistance. (Mus musculus) PubMed

 1431.

The crystal structures of the phosphorylated and unphosphorylated states of the tyrosine kinase CapB together with the activator domain of its cognate transmembrane modulator CapA (CapB). (Mus musculus) PubMed

 1432.

We were able to create mutants in either of the putative ribitol phosphate polymerases (encoded by tarK and tarL) without affecting teichoic acid levels in the S. aureus cell wall.[TarK and TarL in strain RN4220] (Mus musculus) PubMed

 1433.

Staphylococcal accessory regulator (sarR) acts as a stimulator of aur (aureolysin) and sspA (serine protease) transcription, and does not require sarA [sarR, aur, sspA] (Mus musculus) PubMed

 1434.

there were no differences in enterotoxin genes between S. aureus strains isolated from controls compared with nasal polyposis patients. (Mus musculus) PubMed

 1435.

Two distinctive features of DkgB are a structural Mg2+ site and an associated Asp*water*Mg2+ network that extends toward the active site locale (DgkB). (Mus musculus) PubMed

 1436.

S. aureus differentially regulates IsdG and IsdI in response to alterations in iron and haem availability during infection. [IsdI, IsdG] (Mus musculus) PubMed

 1437.

analysis of a heme-binding mechanism for IsdH-NEAT3 that involves multimerization [IsdH] (Mus musculus) PubMed

 1438.

the overexpression, purification, and functional reconstitution of Sav1866 are described in detail. (Mus musculus) PubMed

 1439.

MgrA regulates virulence factors important for establishment and progression of septic arthritis and sepsis. [MgrA] (Mus musculus) PubMed

 1440.

two novel genes coding for two superantigens, staphylococcal enterotoxins S and T (SES and SET), were identified (Mus musculus) PubMed

 1441.

The findings indicate that NorB can facilitate bacterial survival when they are overexpressed in a staphylococcal abscess and may contribute to the relative resistance of abscesses to antimicrobial therapy. New Gene: NorB (Mus musculus) PubMed

 1442.

The strains belonging to coaulase gene restriction fragment length polymorphism pattern L5 and L1 appeared to be the major types of methicillin-resistant Staphylococcus aureus isolasted from bacteremia(Coagulase). (Mus musculus) PubMed

 1443.

We show that colonizing isolates of S. aureus can be agr defective and that heterogeneous mixutres of agr positive and afr defective organisms may be present. [Agr] (Mus musculus) PubMed

 1444.

TCR binding affinity of SEC2 could be altered by substituting the AAs at position 20 & 22 to increase its superantigen activity & antitumor response. SEC2 T20L/G22E had more of these activities without increased vomiting or fever[SEC2] (Mus musculus) PubMed

 1445.

The ABC proteins VgaAv and VgaA were found to be responsible for the reduced susceptibility to pleuromutilins exhibited by these six isolates. [VgaA, VgaAv] (Mus musculus) PubMed

 1446.

Results show that the inability of a sarA mutant to repress production of extracellular nuclease and multiple proteases have independent but cumulative effects that contribute to the biofilm-deficient phenotype of an S. aureus sarA mutant [sarA]. (Mus musculus) PubMed

 1447.

Low concentrations of Hla change calcium signalling by accelerating pump-driven extrusion of Ca(2+) ions.[Hemolysin A] (Mus musculus) PubMed

 1448.

The authors isolated an inhibitor of IL-8 production from the supernatant and identified it as staphylococcal beta-hemolysin.[beta-hemolysin in strain A17] (Mus musculus) PubMed

 1449.

Agr controls biofilm formation in most of the clinical isolates tested. [agr] (Mus musculus) PubMed

 1450.

The main aim of this study was to evaluate the influence of SigB activity on the fibronectin-binding ability of S. aureus in prototype and cystic fibrosis small-colony variants backgrounds.(SigB) (Mus musculus) PubMed

 1451.

TrmE from Staphylococcus aureus was overexpressed in Escherichia coli. The enzyme was found to crystallize at 295 K when ammonium sulfate was used as a precipitant. X-ray diffraction data were collected to 2.9 A resolution (Mus musculus) PubMed

 1452.

The relationship between egc1, egc2, egc3, agr, and enterotoxins and classification of Staphylococcus aureus from humans and animals is described.[egc1; egc2; egc3; agr] (Mus musculus) PubMed

 1453.

The msa gene plays an important role in biofilm development which is likely due to its role in modulating the expression of sarA (Mus musculus) PubMed

 1454.

These results demonstrate that LukF caused the activation of BM-DCs by triggering a TLR4-dependent signaling pathway and suggests that Luk may affect the host inflammatory response as well as show a cytolytic effect on leukocytes.[LukF] (Mus musculus) PubMed

 1455.

DNA-binding data show that MepR uses a dual regulatory binding mode as the repressor binds the mepA operator as a dimer of dimers, but binds the mepR operator as a single dimer "MepR". (Mus musculus) PubMed

 1456.

These results suggest that certain noncognate AIPs stabilize an inhibitory receptor conformation that may be a critical feature of the ligand-receptor interaction not initially appreciated in previous analyses of agr inhibition.[AgrC] (Mus musculus) PubMed

 1457.

Sigb activity is necessary for biofilm formation which is regulated by protease and agr activity. (Mus musculus) PubMed

 1458.

S. aureus Serine/threonine kinase (STK)- and phosphatse (STP)-mediated reversible phosphorylation reactions play a critical role in proper cell wall architecture, and thus the modulation of antimicrobial resistance, in S. aureus. [STK, STP] (Mus musculus) PubMed

 1459.

CodY in S. aureus not only acts as a repressor for genes involved in nitrogen metabolism but also contributes to virulence gene regulation by supporting as well as substituting for agr function.[CodY] (Mus musculus) PubMed

 1460.

This work identifies Asn-108 as a key residue in the translocation pathway of SdcS, accessible in different states from both sides of the membrane.[SdcS] (Mus musculus) PubMed

 1461.

TSST-1 production is not directly associated with the agr structure. [tst, agr] (Mus musculus) PubMed

 1462.

Carriage of both fnbA and fnbB and growth at 37 degrees C promote MRSA biofilm development, further supporting a role for the FnBPA and FnBPB surface proteins in the pathogenesis of MRSA device-related infections [fnbA; fnbB] (Mus musculus) PubMed

 1463.

The role of each metal binding site of CadC was investigated by mutagenesis.[CadC] (Mus musculus) PubMed

 1464.

levels of sodM and sodA transcription, in particular the sodM transcript, are markedly enhanced in the sarA mutant among the tested sarA family mutants [SodM, sodA, SarA] (Mus musculus) PubMed

 1465.

NtrA is a bifunctional enzyme that exhibits nitroreductase and GSNO reductase activity. New Gene: NtrA (Mus musculus) PubMed

 1466.

Fusidic acid resistance determinants in bacteremia isolates belonged to mutations in FusA, FusB, and FusC. [FusA, FusB, FusC] (Mus musculus) PubMed

 1467.

murA and murZ UDP-N-acetylglucosamine enolpyruvyl transferases catalyze the first step of peptidoglycan biosynthesis. MurA appears to be the primary enzyme utilized. [MurA; MurZ] (Mus musculus) PubMed

 1468.

The authors show that inactivation of the staphylococcal accessory gene regulator sarA leads to dramatic reductions in vancomycin and ciprofloxacin resistance in vancomycin-intermediate and ciprofloxacin-resistant strains of S. aureus. (Mus musculus) PubMed

 1469.

crystal structure of human C3b in the presence of a recombinant form of staphylococcal complement-inhibitor protein [scn] (Mus musculus) PubMed

 1470.

Catalase protects intracellularly survived bacteria by destroying H2O2 produced by the murine peritoneal macrophages. [catalase] (Mus musculus) PubMed

 1471.

MsrR is therefore likely to play a role in cell envelope maintenance, cell separation, and pathogenicity of S. aureus. [MsrR] (Mus musculus) PubMed

 1472.

Support is presented for alpha1 as a dimerization interface in phosphorylated VraR, whereas protein-protein interactions for nonphosphorylated VraR are impeded by extensive disorder in this region.[VraR] (Mus musculus) PubMed

 1473.

we show that Staphylococcus aureus contains two YoeB homologues, both of which function as ribosome-dependent mRNA interferases to inhibit translation initiation in a manner identical to that of YoeB-ec from Escherichia coli. [YoeB-sa1, YoeB-sa2] (Mus musculus) PubMed

 1474.

Crystal structures of SarZ showed that Cys(13) sulfenic acid with an external thiol leads to formation of a mixed disulfide bond. [SarZ] (Mus musculus) PubMed

 1475.

SEA is more potent than SEG in inducing the early transcriptional response of human leukocytes. [SEA, SEG] (Mus musculus) PubMed

 1476.

Essentially complete backbone and stereospecific methyl group resonance assignments for apo-, Zn2 and a 42 kDa apo-CzrA-DNA complex. (CzrA protein) (Mus musculus) PubMed

 1477.

investigated whether mupirocin influences This study evaluated the expression of the ileS-2 gene responsible for high-level mupirocin resistance in S. aureus. (Mus musculus) PubMed

 1478.

crystal structure of a carboxy-terminal truncation mutant (Delta95-120) of MscL from Staphylococcus aureus (SaMscL(CDelta26)) at 3.8 A resolution [MscL] (Mus musculus) PubMed

 1479.

Study reports the solution quaternary structure of homodimeric CzrA bound to a palindromic 28-bp czr operator, a structure that provides an opportunity to compare the two allosteric "end" states of an ArsR family sensor.[CzrA] (Mus musculus) PubMed

 1480.

analysis of exchange of bound ADP on the Staphylococcus aureus replication initiation protein DnaA [DnaA strain RN4220, N18 or NM1003] (Mus musculus) PubMed

 1481.

Three residue changes, T101A, V107S, I116S, are sufficient to convert the autoinducing peptide-recognizing specificity from AgrC-IV to AgrC-I.[AgrC] (Mus musculus) PubMed

 1482.

important role played by SarA in modulating expression of trxB involved in oxidative stress resistance in S. aureus[SarA and trxB, strain not found in entrez] (Mus musculus) PubMed

 1483.

Suggest that OpuC is a TRAP binding protein that acts as a transporter and also plays a role in S. aureus pathogenesis. (Mus musculus) PubMed

 1484.

TRAP plays a role in stress response in Staphylococcus aureus. (Mus musculus) PubMed

 1485.

Description of a new group of variants of the Staphylococcus aureus elastin-binding protein that lacks an entire DNA segment of 180 bp. (Mus musculus) PubMed

 1486.

Panton-Valentine leukocidin gene detected in Staphylococcus aureus strain isolated from a knee arthroprosthesis infection. (Mus musculus) PubMed

 1487.

cysteine protease (Ecp) and a downstream gene coding for a putative inhibitor of the protease form an operon which resembles that of staphopain A in S. aureus. The protease was detected on the cell surface and culture media during growth [Ecp] (Mus musculus) PubMed

 1488.

PIA expression elevated and less vulnerable to environmental conditions than in Staph aureus in device-realated infection model [PIA]. (Mus musculus) PubMed

 1489.

stability of established biofilms depends on sigma(B) activity,however, the slow decay of biofilms under conditions of nutrient limitation reveal its use as an energy-storage molecule to be unlikely. [SigB] (Mus musculus) PubMed

 1490.

Disrupting the hemB biosynthetic gene in S. epidermidis resulted in an small-colony variant (SCV) phenotype.[hemB] (Mus musculus) PubMed

 1491.

The production of polysaccharide intercellular adhesin (PIA) in Staphylococcus epidermidis is regulated indepently by both sigma B and staphylococcal accessory regulator A (SarA). [polysaccharide intercellular adhesin, sigmaB, sarA] (Mus musculus) PubMed

 1492.

The smallest deletion 10-bp long conferring constitutive resistance in the translational attenuator of erm(A) in a naturally occurring S. epidermidis strain of human origin. (Mus musculus) PubMed

 1493.

clpP influenced initial attachment of bacteria on the plastic surface, the first step of biofilm formation.[ClpP] (Mus musculus) PubMed

 1494.

Result suggest that a 28 bp core segment of the ica operator is implicated in the cooperative binding of two IcaR dimers on opposite sides of the duplex DNA (IcaR). (Mus musculus) PubMed

 1495.

SdrG is expressed early during infection in response to specific host environmental cues present in the bloodstream. [SdrG] (Mus musculus) PubMed

 1496.

RecA is involved in genetic deletions and rearrangement of the icaADBC operon of Staphylococcus epidermidis.[recA] (Mus musculus) PubMed

 1497.

Therefore, GdpS affects biofilm formation through a novel c-di-GMP-independent mechanism involving increased icaADBC mRNA levels and exopolysaccharide biosynthesis.[GdpS in strain CSF41498] (Mus musculus) PubMed

 1498.

study investigated maturation processing of native GluSE and that heterologously expressed in Escherichia coli[GluSE] (Mus musculus) PubMed

 1499.

The authors found that oxygen negatively regulates biofilm development by influencing the activity of sigma(B).[sigma factor B in strain 1457] (Mus musculus) PubMed

 1500.

SdrF alone was able to mediate bacterial adherence to implanted ventricular assist device drivelines; SdrF appears to play a key role in the initiation of ventricular assist device driveline infections caused by S. epidermidis [SdrF] (Mus musculus) PubMed

 1501.

presence of the gene encoding SesI among isolates obtained from several patient groups that commonly experienced S. epidermidis infections (SesI, Staphylococcus epidermidis surface protein I) (Mus musculus) PubMed

 1502.

Regulation of biofilm formation by sigma B is a common mechanism in Staphylococcus epidermidis and is not mediated by transcriptional regulation of sarA. (Mus musculus) PubMed

 1503.

ACME (arginine catabolic mobile element)-arcA-positive isolates were found in meticillin-resistant Staphylococcus haemolyticus (MRSH) with a high prevalence and clonal diversity. {ACME-arcA] (Mus musculus) PubMed

 1504.

The protein product of the S. sciuri mecA can efficiently participate in cell wall biosynthesis and build a cell wall using the cell wall precursors characteristic of the S. aureus host [MECA] (Mus musculus) PubMed

 1505.

The protein product of pbpD was identified as PBP4 with a molecular mass of 84 kDa, one of the six penicillin binding proteins present. [pbpD] (Mus musculus) PubMed

 1506.

Our results provide further support for the proposition that the resistance determinant mecA of methicillin-resistant Staphylococcus strains has evolved from S. sciuri pbpD (Mus musculus) PubMed

 1507.

Experimental animal infection suggested that an inactivation of dipeptidyl peptidase IV attenuates greatly its high virulence of Chinese virulent strains of SS2.[dipeptidyl peptidase IV] (Mus musculus) PubMed

 1508.

various expression levels of glucosyltransferase isozymes are associated with the ability of distinct Streptococcus mutans genotypes to grow as biofilms [GtfB, GtfC] (Mus musculus) PubMed

 1509.

role for enolase in S. mutans attachment, clearance, or breach of the bloodstream barrier [alpha-enolase] (Mus musculus) PubMed

 1510.

HtrA plays an important role in the biogenesis of extracellular proteins including surface associated glycolytic enzymes and in biofilm formation of S. mutans.( HtrA ) (Mus musculus) PubMed

 1511.

Study demonstrates that mutacin I gene regulation can be divided into two pathways: that dependent on irvA (an inducible repressor) and irvA-independent.[mutacin I, irvA] (Mus musculus) PubMed

 1512.

data are consistent with a role for GbpA in facilitating development of biofilms harboring taller microcolonies via binding to alpha-1,6-linkages within glucan [GbpA] (Mus musculus) PubMed

 1513.

variation in comC among 36 clinical strains of S. mutans collected from geographically diverse sources is reported [comC] (Mus musculus) PubMed

 1514.

Two genes, designated as relP and relQ, encoding novel enzymes that are directly involved in (p)ppGpp synthesis, are identified.[RelP, RelQ] (Mus musculus) PubMed

 1515.

In Strep. mutans, lactoylglutathione lyase is involved in the detoxification of methylglyoxal. [lactoylglutathione lyase] (Mus musculus) PubMed

 1516.

Based on the enzyme-regulator complex structure observed in this study, an allosteric mechanism for dCD regulation, is proposed.[dCD] (Mus musculus) PubMed

 1517.

corresponding residues of alpha-1,6-hydrolyzing enzymes participate in the determination of the substrate specificity of these enzymes[dextran glucosidase ] (Mus musculus) PubMed

 1518.

The SmFnB protein of S. mutans is a fibronectin-binding protein that may contribute to the pathogenesis of infective endocarditis.[SmFnB] (Mus musculus) PubMed

 1519.

Inactivation of ComCDE, HK/RR11 or both systems attenuate the virulence and cariogenicity of S. mutans. [ComC, ComD, comE, HK, RR11] (Mus musculus) PubMed

 1520.

results suggest that RecA has a relationship with biofilm formation [RecA AND Streptococcus mutans MT8148] (Mus musculus) PubMed

 1521.

The gene dut, encoding dUTPase from the dental pathogen Streptococcus mutans, was amplified from S. mutans genomic DNA.[dut] (Mus musculus) PubMed

 1522.

OXA1 complements a lack of yidC2 in S. mutans.[yidC2] (Mus musculus) PubMed

 1523.

identified novel LPXTG anchored surface antigen containing leucine-rich repeat (LRR) motifs that elicits protective immunity [LrrG] (Mus musculus) PubMed

 1524.

Lnu(C) confers resistance to lincomycin by adenylylation of lincomycin [Lnu(C)] (Mus musculus) PubMed

 1525.

scaAB gene encoding for putative adherence and aggregation factor was cloned and sequenced; its inactivation increased the tendency of Streptococcus agalactiae to aggregation. (Mus musculus) PubMed

 1526.

C5a peptidase binding to integrins by the Arg-Gly-Asp motifs may stabilize conformational changes required for substrate binding [C5a peptidase] (Mus musculus) PubMed

 1527.

data suggest that a minimum intracellular concentration of the delta subunit of RNA polymerase is necessary for this organism to cause disease [RNA polymerase delta subunit] (Mus musculus) PubMed

 1528.

These results demonstrate considerable genetic diversity of the bac (C protein beta-antigen}gene and upstream regions of invasive and noninvasive GBS, which may contribute to the variability of bac expression levels among strains [Bac] (Mus musculus) PubMed

 1529.

gene encoding Srr-2 located within a putative accessory secretory locus that included secY2 & secA2 homologues; results indicate the restriction digest pattern III-3/ST-17 lineage expresses Srr-2 & is highly virulent in model of neonatal sepsis [Srr-2] (Mus musculus) PubMed

 1530.

study shows that CAMP factor binds to GPI-anchored proteins, and that this interaction involves the carbohydrate core of the GPI-anchor (Mus musculus) PubMed

 1531.

In frame deletion showed that GBS80 is a major component protein of the antigenic pilus-like structures in Streptococcus agalactiae. (Mus musculus) PubMed

 1532.

RovS specifically binds to the promoter regions of fbsA. (RovS) (Mus musculus) PubMed

 1533.

To our knowledge, this is the 1st report of erm(T) in GBS, the 2nd bacterial species from humans in which the erm(T) gene has been identified, and the 3rd erm gene to be found in inducibly clindamycin resistant GBS.[erm(T)] (Mus musculus) PubMed

 1534.

FbsA-induced Fbg aggregates consist of thicker fibers organized in a cage-like structure[FbsA--fibrinogen-binding protein expressed ] (Mus musculus) PubMed

 1535.

results of the present study support the conclusion that CAMP factor does not bind to immunoglobulin IgG [CAMP factor] (Mus musculus) PubMed

 1536.

study concludes that a chromosomally integrated, composite transposon is associated with ermB-type macrolide resistance in GBS [ErmB] (Mus musculus) PubMed

 1537.

Deletion of the srr-1 gene in the genome of S. agalactiae revealed that this gene plays a role in bacterial binding to human K4 and that it is involved in adherence to epithelial HEp-2 cells.[Srr-1] (Mus musculus) PubMed

 1538.

These results are consistent with the hypothesis that ScpB binds to a motif created by the juxtaposition of multiple Fn molecules.[ScpB] (Mus musculus) PubMed

 1539.

sortases are responsible for polymerization of the pilus structure, while SrtA is required to covalently attach it to the cell wall, utilizing ancillary pilus subunit GBS150 as the anchor protein.[SrtA and SrtC in strain 515] (Mus musculus) PubMed

 1540.

Group B protective surface protein and 5'-nucleotidase family protein were 2 major immunoreactive proteins detected in the whey of infected cows. [Group B protective surface protein, 5'-nucleotidase family protein] (Mus musculus) PubMed

 1541.

The MtaR transcription factor controls genes involved in arginine transport and biosynthesis, methionine transporters, virulence factors, and plasminogen activators. [MtaR] (Mus musculus) PubMed

 1542.

CiaR is a crucial factor for intracellular survival and disease pathogenesis.[CiaR] (Mus musculus) PubMed

 1543.

CspA abolished the abilities of CXC chemokines to attract and activate neutrophils. [CspA] (Mus musculus) PubMed

 1544.

Serine-rich repeat 1 glycoprotein (srr-1 protein)plays an important role in crossing the blood-brain barrier and in the development of streptococcal meningitis. (Mus musculus) PubMed

 1545.

lmb gene has been cloned, expressed in Escherichia coli, purified and crystallized[laminin-binding protein ] (Mus musculus) PubMed

 1546.

preliminary x-ray structure [gammaGCS-GS] (Mus musculus) PubMed

 1547.

results support the hypothesis of an allosteric transition from a conformation with low affinity for ATP to a form with high affinity, which would be induced by the presence of ATP or GTP [UMP kinase] (Mus musculus) PubMed

 1548.

identified ComW as a new positive factor involved in regulation of competence for genetic transformation in Streptococcus pneumoniae [ComW] (Mus musculus) PubMed

 1549.

COOH-terminal region could act as a pedestal, placing the active site in proximity to the peptidoglycan (peptidoglycan synthesis regulatory factor (PBP3)) (Mus musculus) PubMed

 1550.

localization and properties studied, particularly polymerization in an ATP-dependent manner [FtsA, strain Rx1] (Mus musculus) PubMed

 1551.

The biochemical characterization of one alpha-galactosyltransferase, WciS (Cap8H), a member of GT family 4 is reported.[WciS; Cap8H] (Mus musculus) PubMed

 1552.

while comW is not needed for ComX (sigma(X)) synthesis, it acts both in stabilization of sigma(X) and in its activation (ComW and ComX) (Mus musculus) PubMed

 1553.

The genotype of pbp1a, pbp2x, pbp2b, mefA, and ermB of S. pneumoniae strains isolated from children with community acquired pneumonia are reported.[pbp1; pbp2x; pbp2b; mefA; ermB] (Mus musculus) PubMed

 1554.

a role for srtA as a pneumococcal fitness factor in experimental models of pneumonia and bacteraemia [sortase A] (Mus musculus) PubMed

 1555.

initiation of capsule repeat unit formation by the transfer of a sugar to a lipid acceptor catalyzed by Cps2E; data indicated that Cps2E was catalyzing the addition of Glc-1-P to a polyprenyl phosphate acceptor, likely undecaprenyl phosphate [Cps2E] (Mus musculus) PubMed

 1556.

A reaction mechanism is proposed on the basis of kinetic data, the structural model of the Pce:NPPC complex, and the currently accepted mechanism for other Zn-metallophosphoesterases [Pce] (Mus musculus) PubMed

 1557.

results suggest that the interaction between PspC and complement regulatory factor H contributes to pneumococcal virulence. [PspC] (Mus musculus) PubMed

 1558.

analysis of penicillin-binding protein 1a (PBP1a) sequences from drug-resistant clinical strains reveals the existence of a mutational hotspot at the entrance of the catalytic cleft [PBP1a] (Mus musculus) PubMed

 1559.

role of the spr0370-0371 operon containing a putative alkylhydroperoxidase D homologue in pneumococcal virulence and response to oxidative stress [spr0370, spr0371] (Mus musculus) PubMed

 1560.

in vitro transcriptional changes in pneumococcal rr09 mutants of two strains, D39 and TIGR4, by microarray analysis [rr09] (Mus musculus) PubMed

 1561.

The results showed that the response regulator (RR) and histidine kinase (HK06) regulate virulence factors CbpA and PspA. [RR, HK06] (Mus musculus) PubMed

 1562.

Several genes of the GlnR regulon are required at different sites during pathogenesis, with glnA contributing to colonization and survival in the blood and glnP important for survival in the lungs and transition from the lungs to the blood.[glnR] (Mus musculus) PubMed

 1563.

findings suggest that SpxR positively regulates spxB transcription in response to energy and metabolic state; SpxR is required for full virulence in a murine model of infection [SpxR] (Mus musculus) PubMed

 1564.

PsaR is responsible for the counteracting effects of Mn2+ and Zn2+ on the expression of several virulence genes in S. pneumoniae, suggesting that the ratio of these metal ions exerts an important influence on pneumococcal pathogenesis.[PsaR] (Mus musculus) PubMed

 1565.

The pclA mutant was defective in adherence and invasion of host cells in vitro [PclA] (Mus musculus) PubMed

 1566.

Insertion mutagenesis in parent and pcsB(+) merodiploid strains indicated that pcsB is essential in serotype 2 S. pneumoniae D39. (Mus musculus) PubMed

 1567.

Data show that termination of the transcriptional activity of ComX is not dependent on proteolysis of ComW. New Gene: ComW (Mus musculus) PubMed

 1568.

PsaR of D39 and TIGR4 has a strain-specific role in global gene expression and in the development of bacteraemia in mice. [PsaR] (Mus musculus) PubMed

 1569.

The contribution of PpmA to virulence can be explained by its strain-specific role in adherence to epithelial cells and contribution to the evasion of phagocytosis. [PpmA/proteinase maturation protein A] (Mus musculus) PubMed

 1570.

phage-encoded streptodornase identified through mass spectroscopy, nucleotide sequence, cloning and expression [Sda1 strain M1T1] (Mus musculus) PubMed

 1571.

global regulatory factor that contributes to growth phase-dependent synthesis of proteins associated with secondary metabolism and oxidative and thermal stress responses [Streptococcus pyogenes NZ131 (serotype M49), Rgg] (Mus musculus) PubMed

 1572.

two genotypes of prtF2 (a fibronectin binding protein), pfbp and fbaB, are described [prtF2] (Mus musculus) PubMed

 1573.

the mef(A) gene is carried on different chromosomal genetic elements depending on whether the isolates are susceptible or resistant to tetracycline[mefA] (Mus musculus) PubMed

 1574.

crystal structure of the catalytically inactive mutant IdeS-C94S by x-ray crystallography at 1.9-A resolution {IdeS] (Mus musculus) PubMed

 1575.

Newly discovered protease IdeS (IgG-degrading enzyme of S. pyogenes, also known as Mac-1-like protein) seems to be atypical cysteine protease with strict specificity for IgG cleavage due to an exosite recognizing the CH2 domain in IgG Fc fragment. [IdeS] (Mus musculus) PubMed

 1576.

ciprofloxacin resistance due to point mutations in topoisomerase IV subunit C encoded by parC, mainly replacement of serine-79 by alanine. [ParC] (Mus musculus) PubMed

 1577.

Data show that the recombinant Scl protein p176 promotes adhesion and spreading of human lung fibroblast cells through an alpha2beta1 integrin-mediated interaction [sc1] (Mus musculus) PubMed

 1578.

The efflux of telithromcyin from S. pyogenes, resulting in reduced activity, is related to the presence of the mef(A) gene. (Mus musculus) PubMed

 1579.

A comparison different mef(A) elements of Streptococcus pyogenes for a possible chimeric genetic nature, i.e. a transposon inserted into a prophage. [MefA] (Mus musculus) PubMed

 1580.

data indicate that human Fibrinogen bound to Streptococcus pyogenes M5 protein promotes phagocytosis resistance by inhibiting complement deposition via the classical pathway [M5 protein] (Mus musculus) PubMed

 1581.

The present study investigated an association between the presence of the prtF2 gene and internalisation efficiency in group A streptococci isolated from patients with invasive disease. [prtF2] (Mus musculus) PubMed

 1582.

findings suggest CovR regulation of the covR promoter (Pcov) is direct; CovR was sufficient to mediate repression of Pcov; this repression was enhanced by phosphorylation of the protein [CovR] (Mus musculus) PubMed

 1583.

prtF1 is associated with erythromycin resistance [prtF1] (Mus musculus) PubMed

 1584.

study presents evidence for a novel protease-protease inhibitor couple, SpeB-Spi, in the Streptococcus pyogenes[cysteine protease SpeB] [Spi] (Mus musculus) PubMed

 1585.

MsmR positively regulates FCT region genes including Nra and cytolysin-mediated translocation system genes [MsmR] (Mus musculus) PubMed

 1586.

SpeB could cause the mitochondria damage to the polymorphonuclear cells, preventing immune clearance at an early infectious stage (SpeB) (Mus musculus) PubMed

 1587.

controls iron homeostasis and has a role in disease production (MtsR - Mts repressor) (Mus musculus) PubMed

 1588.

CovR is sufficient to repress transcription from the sag promoter (CovR) (Mus musculus) PubMed

 1589.

The prevention of the cell surface export of SDH affects the virulence properties of group A Streptococcus (GAS). (Mus musculus) PubMed

 1590.

NADase enhance S.pyogenes virulence in vivo. (NADase) (Mus musculus) PubMed

 1591.

crystal structure of delta1-pyrroline-5-carboxylate (P5CR) determined at 2.0 angstroms [P5CR] (Mus musculus) PubMed

 1592.

allelic diversity of streptococcal DNase B (sdaB) gene was investigated in 83 strains with 14 emm genotypes; distribution of each allele was generally emm genotype-specific [DNase B (sdaB)] (Mus musculus) PubMed

 1593.

required for virulence in zebrazfish and role in iron acquisition pathway both in vitro and in vivo [SiuG] (Mus musculus) PubMed

 1594.

RscA is a member of the MDR1 family of ABC transporters, is required for growth of GAS at 40 degrees and is repressed by CovR [RscA][CovR] (Mus musculus) PubMed

 1595.

data indicate that binding of human plasma proteins plays an important role in determining the location of opsonic and non-opsonic epitopes in streptococcal M5 protein [M5 protein] (Mus musculus) PubMed

 1596.

Seroconversion of IdeS in patients with pharyngotonsillitis and erysipelas leads to inactivation of enzyme activity, supporting the view that the enzyme plays an important role during streptococcal infection [IdeS] (Mus musculus) PubMed

 1597.

findings show that serum opacity factor (SOF) interacts with HDL in human blood by binding to apoA-I and apoA-II and causing the release of HDL lipid cargo, which coalesces to form lipid droplets, resulting in opacification [SOF] (Mus musculus) PubMed

 1598.

Results describe a eukaryotic-type signaling system in group A Streptococcus, including a eukaryotic-type Ser/Thr kinase (SP-STK) and phosphatase (SP-STP) and their endogenous substrate histone-like protein (SP-HLP) [SP-STK, SP-STK]. (Mus musculus) PubMed

 1599.

DNase Sda1 is both necessary and sufficient to promote Group A Streptococcus neutrophil resistance and virulence in a murine model of necrotizing fasciitis. [Sda1] (Mus musculus) PubMed

 1600.

CodY protein identified as a pleiotropic transcription regulator with global features [CodY] (Mus musculus) PubMed

 1601.

the high virulence of the type M3-f strain is associated with the decreased binding of type M3-f CsrR to its target sequences [CsrR] (Mus musculus) PubMed

 1602.

study shows for the first time that residues Arg101, Arg114, His102, and His115 in both the a1 and a2 repeat domains of PAM can mediate high affinity plasminogen binding [PAM] (Mus musculus) PubMed

 1603.

signal sequence of M protein promotes secretion at the division septum, whereas that of PrtF preferentially promotes secretion at the old pole [M protein; PrtF] (Mus musculus) PubMed

 1604.

phosphorylated CovR represses transcription of rivR directly by binding to conserved sequences located downstream from the promoter to block procession of RNA polymerase [CovR] (Mus musculus) PubMed

 1605.

ScpC represents a novel GAS virulence factor functioning to directly inactivate a key element of the host innate immune response.[ScpC] (Mus musculus) PubMed

 1606.

Here, we describe a novel plasminogen-binding M protein, the plasminogen-binding group A streptococcal M protein (PAM)-related protein (Prp). [Prp] (Mus musculus) PubMed

 1607.

The results provide further evidence that Rgg contributes to growth phase-dependent gene regulation in strain NZ131.[Rgg] (Mus musculus) PubMed

 1608.

These data establish that cytolysin-mediated translocation is discriminatory, and that NAD glycohydrolase is a multidomain protein that plays an active role in its translocation. [NAD glycohydrolase] (Mus musculus) PubMed

 1609.

analyzed the SpeC-Vbeta2.1 interaction by mutating all SpeC residues that make contact with Vbeta2.1 and determined the energetic and functional consequences of these mutations [SpeC] (Mus musculus) PubMed

 1610.

results support the involvement of NAPlr in inflammatory cell accumulation in glomerular tufts and functional abnormality of glomerular microvasculature such as hyperpermeability [NAP1r] (Mus musculus) PubMed

 1611.

structure-function studies of previously uncharacterized glycogen-binding modules in the surface-anchored pullulanase PulA; multivalent binding to glycogen leads to a strong interaction with alveolar type II cells in mouse lung tissue [PulA] (Mus musculus) PubMed

 1612.

silC and silCR form a novel regulatory circuit that controls the streptococcal invasion locus transcription [SILC, SILCR] (Mus musculus) PubMed

 1613.

data suggest that PerR has a greater impact on the transcriptome than can be predicted by its binding sites and that pmtA functions to link metal homeostasis and oxidative stress responses[pmtA] (Mus musculus) PubMed

 1614.

We conclude that DRS (distantly related to SIC[streptococcal inhibitor of complement]) shares several of the properties of SIC, and therefore can be considered an important virulence factor of M12 GAS and an aid to colonization of the host mucosae. (Mus musculus) PubMed

 1615.

The results obtained by quantitative real-time PCR using the M49 strain NZ131 showed that CodY influenced Streptococcus pyogenes gene activity in a dynamic fashion, with differential responses detected for 26 genes.[CodY protein] (Mus musculus) PubMed

 1616.

This study is the first to characterize global gene regulation by a group A Streptococcus two-component system in response to a specific environmental stimulus.[CsrR, CsrS] (Mus musculus) PubMed

 1617.

describe how bacteriophage-encoded group A Streptococcus DNase (Sda1), which facilitates the pathogen's escape from neutrophil extracellular traps, serves as a selective force for control of virulence regulatory sensor kinase mutation[ Sda1 ] (Mus musculus) PubMed

 1618.

crystal structures of GluR from Streptococcus pyogenes in both inhibitor-free and inhibitor-bound forms [MurI or glutamate racemase] (Mus musculus) PubMed

 1619.

In this study, the addition of M1 protein to human blood or purified peripheral blood mononuclear cells led to a dose-dependent increase of pro-coagulant activity, which was mediated by an upregulation of tissue factor on monocytes. [M1 protein] (Mus musculus) PubMed

 1620.

study reports that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation [M1 protein] (Mus musculus) PubMed

 1621.

Soluble M1 protein is a novel streptococcal superantigen, which contributes to the excessive T cell activation and hyperinflammatory response seen in severe invasive streptococcal infections. (Mus musculus) PubMed

 1622.

Heterologous expression in Escherichia coli showed that SipA2, along with the pilus backbone protein T3 and the sortase SrtC2, is required for polymerization of the T3 protein.[SipA in strain GAS AM3] (Mus musculus) PubMed

 1623.

The data revealed that, in Plasminogen, the species specificity of VEK-30 binding in human and mice is entirely dictated by two lysine residues.[PAM protein] (Mus musculus) PubMed

 1624.

HtrA plays an indirect role in the maturation of cysteine protease SpeB.[HtrA, SpeB] (Mus musculus) PubMed

 1625.

we have identified a functional interaction between Scl1 and plasma FH, which may contribute to GAS evasion of complement-mediated opsonization and phagocytosis.[Scl1 in strain MGAS6169] (Mus musculus) PubMed

 1626.

protein H and M1 protein of the highly pathogenic S. pyogenes AP1 strain bind full-length beta(2)GPI and prevent its processing into antibacterial peptides.[protein H and M1 in strain AP1] (Mus musculus) PubMed

 1627.

These results suggest a novel SPE B mechanism, one which degrades serum C3 and enables GAS to resist complement damage and opsonophagocytosis. [SpeB in strain A20] (Mus musculus) PubMed

 1628.

Our data indicate that horizontal transfer of SSA by lysogenic phages among GAS can occur across the M-type barrier; these data also provide further support for the hypothesis that toxigenic conversion can occur via lysogeny between species. [SSA] (Mus musculus) PubMed

 1629.

1)Rgg is identified as a novel sensoregulator of streptococcal H2O2 resistance.(rgg) 2) ahpCF operon knockouts demonstrated that the gene products decompose H2O2 and protect GAS against peroxide stress. (ahpC)(ahpF) (Mus musculus) PubMed

 1630.

SPEA and SMEZ does not had effect on global protein expression and on transcription of genes encoding the secreted exoproteins.[SPEA, SMEZ] (Mus musculus) PubMed

 1631.

In this report Nra activates pilus gene transcription and MsmR represses nra and pilus gene transcription [Nra], MsmR] (Mus musculus) PubMed

 1632.

Stimulation of the delta(2) (ParA) ATPase activity and its polymerization on DNA required ability of omega(2) (ParB) to bind parS DNA and its N-terminus (ParA and ParB). (Mus musculus) PubMed

 1633.

the findings provide in vivo support of the hypothesis that SpeB-mediated inactivation of LL-37 at the streptococcal surface represents a bacterial resistance mechanism at the infected tissue site in patients with severe GAS tissue infections.[SpeB] (Mus musculus) PubMed

 1634.

Streptococcal pyrogenic exotoxin B (SPE B) potentially causes immunosuppression by cleaving human S-adenosylhomocysteine hydrolase (AdoHcyase). (Mus musculus) PubMed

 1635.

IgG and 1/2Fc binding to the streptococcal surface was studied and correlated to IdeS activity.[IdeS] (Mus musculus) PubMed

 1636.

These data indicate that Dpr provides protection from hydrogen peroxide stress by preventing the Fenton reaction, and Dpr was identified as a novel stress protein that protects against several stresses in group A streptococci.[Dpr in strai A-20] (Mus musculus) PubMed

 1637.

challenge with the ScpC mutant that does not degrade IL-8 resulted in more severe systemic disease with higher bacteremia levels and mortality than did challenge with the wild-type strain.[ScpC in strain S291] (Mus musculus) PubMed

 1638.

Mga was required for autoaggregation and biofilm-like growth on an abiotic surface. [Mga] (Mus musculus) PubMed

 1639.

TrxR is the first TCS shown to regulate Mga expression. Because it is CovR repressed, TrxR defines a new pathway by which CovR can influence Mga to affect pathogenesis in the GAS.[TrxR in strain SF370] (Mus musculus) PubMed

 1640.

covR/S operon generates covR/S transcript and monocistronic covR transcripts [covR/S from strains A-20, SF370, SW117, NZ131, SW602, SW603 or SW604 (Mus musculus) PubMed

 1641.

The authors suggest that low level of luxS expression seems to provide an advantage for bacterial survival in conditions that can be encountered during infections.[luxS] (Mus musculus) PubMed

 1642.

Lzp is a novel immunoglobulin-binding protein that may play a role in helping S. pyogenes escape detection by the host immune system. (Lzp) (Mus musculus) PubMed

 1643.

analysis of a prokaryotic Scl1 collagen sequence motif that mediates binding to human collagen receptors, integrins alpha2beta1 and alpha11beta1 [Scl1] (Mus musculus) PubMed

 1644.

CovR and CovS mediates the grow under iron starvation and the presence of human antimicrobial peptide LL-37.[CovR and CovS] (Mus musculus) PubMed

 1645.

Srv (streptococcal regulator of virulence) is required for biofilm formation, and increased levels of SpeB (cysteine protease) contribures to loss of biofilm phenotype. [Srv, SpeB] (Mus musculus) PubMed

 1646.

Modeling of the ScpA-C5a complex indicates that the substrate binds with carboxyl-terminal residues (65-74) extended through the active site and core residues (1-64) forming exosite-type interactions with the Fn2 domain.[ScpA in strain B220] (Mus musculus) PubMed

 1647.

Pska regulation by CovR occurs through binding at a single ATTARA consensus binding sequence. [pska, covR] (Mus musculus) PubMed

 1648.

findings suggest that the flexible C-terminal loop of SPE B may play an important role in controlling the substrate binding, resulting in its broad substrate specificity [SPE B] (Mus musculus) PubMed

 1649.

Disruption of vfr markedly increased SpeB production in a clinical strain of S. pyogenes and relieved its growth phase dependency.[vfr] (Mus musculus) PubMed

 1650.

The authors examined the cluster 9 protein Lsp of Streptococcus pyogenes and found that specific deletion of lsp produced mutants highly attenuated in a murine model of soft tissue infection.[Lsp] (Mus musculus) PubMed

 1651.

The authors propose that CovS-mediated regulation of CovR activity plays an important role in the ability of GAS to cycle between pharyngeal and invasive infections.[CovR & CovS] (Mus musculus) PubMed

 1652.

The crystal structure of MtsA explains the distinct roles of metal ligands and also reveals potential secondary binding sites that may explain the binding behavior of MtsA for metal ions other than Fe(2+). (Mus musculus) PubMed

 1653.

The result indicates that SIC plays a role in the inhibition of S. salivarius BLIS.[SIC] (Mus musculus) PubMed

 1654.

The data suggest that Lbp (laminin-binding protein)is primarily a zinc-binding protein, and we suggest that its interaction with laminin in vivo may be mediated via zinc bound to laminin. [Lbp] (Mus musculus) PubMed

 1655.

[serum opacity factor]The SOF-catalyzed reaction is the first to target HDL (high-density lipoprotein) rather than its transporters and receptors in a way that enhances reverse cholesterol transport. (Mus musculus) PubMed

 1656.

The crystal structure of the mature SpeB is presented to 1.55 A, disclosing a homodimer.[SpeB] (Mus musculus) PubMed

 1657.

The production of IL-8 by SPE B in A549 cells is mediated by Fas, and followed by the activation of FADD, caspase 8, MEKK1, ERK and NF-kappaB.[SPEB] (Mus musculus) PubMed

 1658.

Crystallization and preliminary crystallographic analysis of an Enterococcus faecalis repressor protein, CylR2 (Mus musculus) PubMed

 1659.

crystal structure of catalase [catalase] (Mus musculus) PubMed

 1660.

enterococci use CylL(L)'' to actively probe the environment for target cells, and when target cells are detected, allows the organism to express high levels of cytolysin in response [CylL(L) strain FA2-2] (Mus musculus) PubMed

 1661.

important for virulence as well as stress response, and anti-Gls24 immune rabbit serum shows protection against E. faecalis infection in a mouse peritonitis model. [Gls24] (Mus musculus) PubMed

 1662.

results indicate that gelatinase is important for the successful in vitro translocation of E. faecalis across human enterocyte-like T84 cells [GelE] (Mus musculus) PubMed

 1663.

results indicate that DivIVA is a speceis specific essential gene involved in cell division, cell growth and chromosome segregation [DivIVA] (Mus musculus) PubMed

 1664.

Enterococcus faecalis FabN and FabZ protein domain swapping localizes the structural determinants for isomerase activity [FabN] (Mus musculus) PubMed

 1665.

development of high-level resistance to penicillins and imipenem depends on point mutations of PBP4 at positions 520 and 605 [PBP4] (Mus musculus) PubMed

 1666.

PrgY may sequester or inactivate cCF10 as it is released from the membrane. (cCF10) (Mus musculus) PubMed

 1667.

HypR acts as a transcriptional activator, especially during oxidative stress, and appears to be an important virulence factor [HypR] (Mus musculus) PubMed

 1668.

results indicate that gls24 is important in the pathogenesis of enterococcal endocarditis [gls24] (Mus musculus) PubMed

 1669.

pIP501 tra operon is negatively autoregulated at the transcriptional level by the conjugative DNA relaxase TraA. [TrA] (Mus musculus) PubMed

 1670.

The role of CroR as a direct transcriptional activator of the salB expression in E. faecalis is reported.[CroR; SalB] (Mus musculus) PubMed

 1671.

results show that the FsrABC system positively & negatively regulates expression of numerous genes between late exponential phase & early stationary phase; also the FsrABC system regulon is independent of the expression of gelE and sprE[FsrA, FsrB, FsrC] (Mus musculus) PubMed

 1672.

Increased Ace expression correlated with increased collagen and laminin adhesion. (Ace) (Mus musculus) PubMed

 1673.

The effect of siamycin I on the metabolism of fsrC, fsrA, and gelE-sprE transcripts and the subsequent production of gelatinase biosynthesis-activating pheromone is reported.[gelE; sprE; fsrA; fsrC] (Mus musculus) PubMed

 1674.

Phosphopantetheine adenylyltransferase is an essential enzyme in the coenzyme A biosynthetic pathway has been cysstallized and the X-ray diffraction data were collected. [phosphopantetheine adenylyltransferase] (Mus musculus) PubMed

 1675.

overall reaction rate of HMG-CoA synthase was increased 140-fold[HMG-CoA synthase] (Mus musculus) PubMed

 1676.

E. faecalis GelE hydrolyzed C3a and also mediated the degradation of C3b, thereby inhibiting opsonization and the formation of the membrane attack complex resultant from the activation of the complement cascade triggered by C3 activation.[GelE] (Mus musculus) PubMed

 1677.

PrkC, a one-component signaling protein containing a eukaryotic-type Ser/Thr kinase domain, modulates inherent antimicrobial resistance and intestinal persistence of E. faecalis. [PrkC] (Mus musculus) PubMed

 1678.

we report the crystal structure of the AzoA from E. faecalis determined at 2.07 A resolution with bound FMN ligand[AzoA] (Mus musculus) PubMed

 1679.

Gel retardation assays showed that the CroR regulator binds specifically to the glnQHMP promoter.[CroR] (Mus musculus) PubMed

 1680.

study describes the crystal structure of ACE19 and compares it with CNA19 crystal structure; present modeling studies presented to localize the collagen-like peptide interactions with ACE19 [ACE protein] (Mus musculus) PubMed

 1681.

An ebpR deletion (DeltaebpR) mutant was found to have reduced ebpABC expression with loss of pilus production and a defect in primary adherence with, as a consequence, reduced biofilm formation.[ebpR] (Mus musculus) PubMed

 1682.

Surface protein ElrA has a role in the E. faecalis infectious process in vivo and may contribute to E. faecalis virulence by stimulating the host inflammatory response. (ElrA) (Mus musculus) PubMed

 1683.

EF_0783 is currently involved in the lysozyme resistance of E. faecalis, peptidoglycan O acetylation and de-N-acetylation are not the main mechanisms conferring high levels of lysozyme resistance to E. faecalis.[EF0783] (Mus musculus) PubMed

 1684.

Deletion of bps had a major effect on virulence in murine UTIs; deletion of srtA from OG1RF from a bps mutant had a pronounced effect on biofilm, suggesting that Bps and/or the proteins it anchors may compensate for the loss of SrtA function.[ArtA,Bps] (Mus musculus) PubMed

 1685.

the thiol peroxidase (Tpx) deletion mutant showed attenuated virulence in a mouse peritonitis model.[Tpx in strai JH2-2] (Mus musculus) PubMed

 1686.

the high-resolution solution structure of the 15.4 kDa homodimer CylR2, the regulator of cytolysin production from Enterococcus faecalis (Mus musculus) PubMed

 1687.

DivIVA self-interacts and forms a 10-12 multimeric complex (DivIVA). (Mus musculus) PubMed

 1688.

indicate that together with KPR, D-ManDH constitutes a new family of D-2-hydroxyacid dehydrogenases that act on C3-branched 2-ketoacid substrates with various specificities for coenzymes and substrates [D-mandelate dehydrogenase] (Mus musculus) PubMed

 1689.

Results showed distinct characteristics in mutation patterns of ermB and ermA. (Mus musculus) PubMed

 1690.

these results indicate that the regulator Ers (PrfA-like transcriptional regulator) has a pleiotropic effect, especially in the cellular metabolism and virulence of E. faecalis. [Ers] (Mus musculus) PubMed

 1691.

A stem-loop sequestering the Fst ribosome binding site is required for translational repression. (Mus musculus) PubMed

 1692.

In the present study, we sum up the characteristics of Ers and provide further evidence that this protein is a member of the PrfA branch of this regulator family. [Ers] (Mus musculus) PubMed

 1693.

Tro-105 is a critical residue for FMN binding in azoreductase. [AzoA] (Mus musculus) PubMed

 1694.

Data show that GntR family transcriptional activator CitO has a role in the transcriptional regulation of the citrate gene cluster of Enterococcus faecalis [CitO] (Mus musculus) PubMed

 1695.

PerA, a gene encoding a putative AraC-type transcriptional regulator, was identified as a regulator of biofilm formation and survival within macrophages and is likely a regulator controlling determinants important to pathogenesis. (Mus musculus) PubMed

 1696.

This study showed that the pHTbeta plamids confers the self-aggregation phenotype on E. faecalis, and that the aggregation was controlled by a traB gene.[traB] (Mus musculus) PubMed

 1697.

Tn5281 is the main cause of transmission of aac(6')-aph(2") to different isolates in the hospitals studied. [aac(6')-aph(2")] (Mus musculus) PubMed

 1698.

paralyzes the human complement system via a two-stage process: by converting circulating C3 to C3b, and by disrupting phagocytosis of human polymorphonuclear leukocytes. [E. faecalis gelatinase GelE] (Mus musculus) PubMed

 1699.

multiple functional domains are important in Asc10-mediated interactions with the host during the course of experimental endocarditis and that in the absence of a functional prgB gene, pCF10 carriage is actually disadvantageous in vivo.[Asc10] (Mus musculus) PubMed

 1700.

Ers regulated glycerol metabolism. [Ers] (Mus musculus) PubMed

 1701.

Crystal structure of fatty acid/phospholipid synthesis protein PlsX from Enterococcus faecalis. (Mus musculus) PubMed

 1702.

Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis (Mus musculus) PubMed

 1703.

Since an in-frame deletion of EF1809 resulted in a severe biofilm defect that could be complemented by the cloned wild-type gene, we have designated EF1809 ebrA (enterococcal biofilm regulator).[EbrA] (Mus musculus) PubMed

 1704.

the crystal structure of the Ef peptide deformylase complex with Met-Ser-Ala was presented. (Mus musculus) PubMed

 1705.

Glutaraldehyde & borane-dimethylamine derivatized EfsQnr by cyclic pentylation of free amines, producing piperidine groups. Crystals diffracted to 1.6 A resolution & were analyzed by single-wavelength anomalous dispersion. (Mus musculus) PubMed

 1706.

The authors demonstrated for the first time that Ace can be considered a virulence factor for E. faecalis.[Ace] (Mus musculus) PubMed

 1707.

Membrane-bound BcrR has a high affinity for its target DNA. BcrR is a bona fide one-component transmembrane signal transduction system. [BcrR] (Mus musculus) PubMed

 1708.

fsrB and to a lesser extent gelE significantly contribute to the virulence of E. faecalis food isolates. [fsrB; gelE] (Mus musculus) PubMed

 1709.

The N-terminal domain of spaA possessed high immunoreactivity. [SpaA] (Mus musculus) PubMed

 1710.

crystal structure of 1,3,6,8-tetrahydroxynaphthlene synthase (THNS) [THNS] (Mus musculus) PubMed

 1711.

the Streptomyces developmental protein WhiD, a member of the WhiB family, binds a [4Fe-4S] cluster (Mus musculus) PubMed

 1712.

experiments demonstrated that AbsA1 possesses both kinase and phosphatase activities that are specific for AbsA2 [AbsA1, AbsA2 strain C530] (Mus musculus) PubMed

 1713.

VanK has a role in vancomycin resistance in Streptomyces coelicolor (Mus musculus) PubMed

 1714.

structure and thermal stability of the first protein (enzyme I, EI) of the PTS in Streptomyces coelicolor is studied by using far-UV circular dichroism (CD) and Fourier transform infrared spectroscopy (FTIR) at pH 7.0 [enzyme I] (Mus musculus) PubMed

 1715.

PhoP and its truncated DBD domain were found to bind with high affinity to an upstream region of the pstS and phoRP-phoU promoters close to the -35 sequence of each of these promoters [PhoP] (Mus musculus) PubMed

 1716.

The wild-type H+-pyrophosphatase , but not a cysteine-less mutant, is reversibly inactivated by oxidation. (Mus musculus) PubMed

 1717.

results strongly suggest that the enzyme responsible for RNA 3'-tail synthesis is polynucleotide phosphorylase (PNPase); moreover, this study shows that both PNPase and the product of SCO3896 are essential[PNPase, SCO3896] (Mus musculus) PubMed

 1718.

Nur is a regulator of nickel homeostasis and antioxidative response in S. coelicolor. (Nur) (Mus musculus) PubMed

 1719.

transcriptional regulation of macs1-fadD1; identification & characterization of a transcriptional activator, AcsR, whose role is to control growth-phase-dependent induction of the macs1-fadD1 operon by binding to an unusual operator [AcsR, macs1, fad1] (Mus musculus) PubMed

 1720.

MreB is not essential for vegetative growth of S. coelicolor, but exerts its function in the formation of environmentally stable spores, and appears to primarily influence the assembly of the spore cell wall. (MreB) (Mus musculus) PubMed

 1721.

The data show that the zinc site in RsrA is comprised of Cys11, His37, Cys41, and Cys44.(RsrA) (Mus musculus) PubMed

 1722.

the core domain and active sites of FtsY and Ffh which are responsible for GTP hydrolysis, were identified; results indicated that Lys residue in the putative GTP binding loop was the crucial residue for the GTPase activity of NG domain [FtsY, Ffh] (Mus musculus) PubMed

 1723.

Studies demonstrate that the increased levels of ribosome recycling factor(RRF) caused by the K88E mutation is responsible for an aberrant stationary-phase event: overproduction of antibiotic [RRF] (Mus musculus) PubMed

 1724.

findings suggest that agl3R is one of a number of homologous proteins in Streptomyces that respond to nutritional and/or environmental signals to control genes that affect morphogenesis and antibiotic production [agl3R] (Mus musculus) PubMed

 1725.

Some crosses between pairs of recA null mutants generated no detectable recombinants, showing for the first time that conjugal recombination in S. coelicolor is recA mediated [recA] (Mus musculus) PubMed

 1726.

The functional actVI-ORFA gene restored expression of actVI-ORF1, which encodes a key reductase in the actinorhodin tailoring step, in the mutant cells, indicating a possible regulatory role of ActVI-ORFA. [ActVI-ORFA] (Mus musculus) PubMed

 1727.

results confirm that AsnO and HasP are required for the beta-hydroxylation and phosphorylation of the Asn residue within calcium-dependent antibiotic [hasP, asnO] (Mus musculus) PubMed

 1728.

Zur, located downstream of the znuACB operon, encoding a putative zinc uptake transporter: Zur (Mus musculus) PubMed

 1729.

cdaX or cchK) encoding MbtH-like proteins in Streptomyces coelicolor is required for biosynthesis of the peptide siderophore coelichelin and the calcium-dependent peptide antibiotic (CDA).[cdaX, cchK] (Mus musculus) PubMed

 1730.

cloY is specifically required for the formation of the 3-amino-4,7-dihydroxy-coumarin moiety of the clorobiocin molecule.[cloY] (Mus musculus) PubMed

 1731.

the N-terminus was dispensable for FtsY GTPase activity, and that the N-domain plays an essential role in the GTPase activity of the NG domain. In addition, the S.scoelicolor FtsY was able to restore function in an E. coli mutant. (Mus musculus) PubMed

 1732.

The studies demonstrate that the subfamily partner CYP158A1, sharing 61% amino acid identity with CYP158A2, can catalyze the same flaviolin dimerization reactions, but it generates just two of the three isomers of biflaviolin that CYP158A2 produces. (Mus musculus) PubMed

 1733.

S. coelicolor ParA provides scaffolding for proper distribution of ParB complexes and consequently controls synchronized segregation of several dozens of chromosomes, possibly mediating a segregation and septation checkpoint.[ParA] (Mus musculus) PubMed

 1734.

These results suggested that the transcription of hppD is subject to coarse and fine control by a complex regulatory system.[hppD, HpdA, HpdR] (Mus musculus) PubMed

 1735.

The septal localization of SffA was dependent on SmeA, suggesting that SmeA may act as an assembly factor for SffA and possibly other proteins required during spore maturation. (Mus musculus) PubMed

 1736.

mutation in the N-terminal domain of germacradienol-geosmin synthase of a catalytically essential serine to alanine results in the conversion of farnesyl diphosphate to a mixture of sesquiterpenes [germacradienol-geosmin synthase ] (Mus musculus) PubMed

 1737.

the phoA, phoC and phoD promoters showed clear differences in the modulation of their expression by PhoP.[PhoP] (Mus musculus) PubMed

 1738.

Further transcriptional analysis on sporulation controlling genes, i.e., whiG, whiB, whiH, and prox, indicated that the regulation of sporulation by ftsY is likely to take effect through whiH.[FtsY and whiH in strain M145] (Mus musculus) PubMed

 1739.

SCO1135 open reading frame identified by the insertion encodes a member of the TetR family of transcriptional regulators.[TetR] (Mus musculus) PubMed

 1740.

in contrast to a previous postulate, Pol I and its paralog are not essential for replication of Streptomyces chromosomes.[PolA in strains 3454 and 3456] (Mus musculus) PubMed

 1741.

A cooperative binding of PhoP initiated at conserved core direct repeats appears to be the mechanism involved in binding of several PhoP monomers to those complex operators (PhoP). (Mus musculus) PubMed

 1742.

The chromosomal interruption of dasA resulted in a carbon-source-dependent vegetative arrest phenotype.[DasA] (Mus musculus) PubMed

 1743.

the deletion of sco0958 produced a dramatic reduction in neutral lipid production, whereas the overexpression of this gene yielded a significant increase in de novo TAG biosynthesis.[sco0958 in strain M145] (Mus musculus) PubMed

 1744.

prokaryotic homolog exhibits remarkable structural similarity to human formylglycine-generating enzyme, including the position of catalytic cysteine residues[ formylglycine-generating enzyme] (Mus musculus) PubMed

 1745.

The paper reports that a cellulose synthase-like protein (CslA(Sc)) in Streptomyces has a function in hyphal tip growth and morphological differentiation.[CslA in strain M145] (Mus musculus) PubMed

 1746.

Antibiotic pathway-specific activators are mediated through the pleiotropic transcriptional repressor DasR, the regulon of which also includes all N-acetylglucosamine-related catabolic genes.[DasR] (Mus musculus) PubMed

 1747.

AbsB controls its own expression by sequentially and site specifically cleaving stem-loop segments of its polycistronic transcript.[AbsB in strain C120] (Mus musculus) PubMed

 1748.

RT-PCR experiments showed that expression of novG was detectable in the absence of NovE, and also that expression of novE occurred in absence of NovG. (Mus musculus) PubMed

 1749.

TrpRS1 is transcriptionally activated by indolmycin and confers resistance to indolmycin. [TrpRS1] (Mus musculus) PubMed

 1750.

OrnA is not transcriptionally or translationally coupled to adpA, a key bldA target for morphological differentiation. [OrnA, adpA, bldA] (Mus musculus) PubMed

 1751.

The SCO5883 mutant did not synthesize undecylprodigiosin, while SCO6673 mutant failed to produce calcium-dependent antibiotic.[SCO5883 and SCO6673 homologs in strain M145] (Mus musculus) PubMed

 1752.

Data compare ActR's interaction with naturally occurring and synthetic molecules to show that pathway intermediates bind to ActR 5- to 10-fold more tightly than actinorhodin itself [ActR]. (Mus musculus) PubMed

 1753.

The endoRNase activity of RNase III is required for the regulation of antibiotic production in S. coelicolor. [Rnc] (Mus musculus) PubMed

 1754.

FilP is an intermediate filament-like protein which has a cytoskeletal function in actinobacterial growth and morphogenesis. [FilP] (Mus musculus) PubMed

 1755.

the purification of NsrR from the obligate aerobe Streptomyces coelicolor. (Mus musculus) PubMed

 1756.

Ppm1 is necessary for the transfer of mannose to endogenous polyprenol phosphate, and glycosylates PstS. [Ppm1] (Mus musculus) PubMed

 1757.

The X-ray structure of the two-domain laccase (small laccase) from Streptomyces coelicolor A3(2) was solved at 2.7-A resolution.[Laccase] (Mus musculus) PubMed

 1758.

HspR role in adaptation to stresses includes influencing expression of key components of the translational apparatus in addition to molecular chaperone and protease-encoding genes[HspR] (Mus musculus) PubMed

 1759.

It is therefore proposed that BldG and SCO3548 form a partner-switching pair that regulates the function of one or more sigma factors in S. coelicolor.[BldG & SCO3548] (Mus musculus) PubMed

 1760.

Compared with wild-type strain M145, the rrdA null mutant exhibited increased undecylprodigiosin production and decreased actinorhodin production. (Mus musculus) PubMed

 1761.

NepA is a bacterial structural cell wall protein that is important for maintenance of spore dormancy. [NepA] (Mus musculus) PubMed

 1762.

PhoP represses directly the transcription of GS genes glnA, glnII, the putative ammonium transporter gene amtB, and the nitrogen regulatory genes glnD and glnK, which form part of the amtB operon (PhoP). (Mus musculus) PubMed

 1763.

Nur contains a unique nickel-specific metal site in addition to a nonspecific common metal site (Nur). (Mus musculus) PubMed

 1764.

GlnR positively regulated the transcription of nasA via specific binding to a cis-element similar but different from the previously characterized consensus sequence. (GlnR)(nasA) (Mus musculus) PubMed

 1765.

report the structure of the Steptomyces coelicolor fatty acid synthase ACP and studies of its binding to malonyl CoA-ACP transacylase.[malonyl CoA-ACP transacylase] (Mus musculus) PubMed

 1766.

SsgB is a conserved activator of developmental cell division in morphologically complex actinomycetes (Mus musculus) PubMed

 1767.

cpb1 took part in the regulation of chitinase expression in S. lividans[chitinase and cpb1] (Mus musculus) PubMed

 1768.

Data suggest that the structure and stability of KcsA reconstituted into native-like membranes differ from those exhibited in detergent solution. (Mus musculus) PubMed

 1769.

role of FtsY in protein secretion [FtsY] (Mus musculus) PubMed

 1770.

KcsA channel inactivation can be described by a kinetic model in which pH(i) controls inactivation through pH-dependent activation [KcsA] (Mus musculus) PubMed

 1771.

Conserved amino acids were mutated in order to investigate a functional role of these residues in catalysis.(acetylxylan esterase A) (Mus musculus) PubMed

 1772.

The results presented here support the idea that ClpP1/P2 ensure post-translational control of ClgR regulon members, including ClgR itself.[ClpP1][ClpP2] (Mus musculus) PubMed

 1773.

Sodium and potassium ions bind competitively to KcsA with distinct affinities and induce different conformations of the ion-bound protein. (KcsA) (Mus musculus) PubMed

 1774.

selectivity and gating functions of Streptomyces lividans KcsA [KcsA] (Mus musculus) PubMed

 1775.

Study of the role of the Tat subunits in complex assembly and stability in the membrane and cytoplasm showed that TatB stabilizes TatC, driving Tat complex assembly is suggested for TatC and TatA is a translocator.[TatA, TatB, TatC protein] (Mus musculus) PubMed

 1776.

the C-terminal domain of KcsA may contribute to the pH dependent opening of the potassium channel (Mus musculus) PubMed

 1777.

A stem-loop structure on the sblA transcript plays a negative role in the regulation of sblA expression and might be involved in the regulation of the specific degradation of the sblA transcript.[sblA] (Mus musculus) PubMed

 1778.

Results describe the structure and activity of full-length KcsA, a prototypical K+ channel, in its open, closed and intermediate states [KcsA]. (Mus musculus) PubMed

 1779.

Data show that in the KcsA potassium channel, the number and strength of hydrogen bonds between residues in the selectivity filter and pore helix determine the rate and extent of C-type inactivation, which can also be engineered in Kv1.2 channels. (Mus musculus) PubMed

 1780.

solid-state NMR studies of the selectivity filter region of KcsA potassium channel[KcsA] (Mus musculus) PubMed

 1781.

S-adenosylmethionine controls the expression of bldH through the TTA-codon control in translating bldH mRNA.[bldH] (Mus musculus) PubMed

 1782.

effect of mutations of Thr75 in the S4 site of theKcsA K+ channel on the cation dependence of the thermal stability of the tetramer, a phenomenon that reflects the structural role of cations in the filter [KcsA] (Mus musculus) PubMed

 1783.

mutation, ion depletion, and K(+) to Na(+) substitution influence SF conformation [KcsA] (Mus musculus) PubMed

 1784.

Channel-opening may follow a three-phase pathway. First, the channel unlocks itself from the closed state; second, it opens; and third, it locks itself in the open conformation.[KcsA] (Mus musculus) PubMed

 1785.

XylR acts as a repressor in the S. lividans xylose operon and xylose isomerase(XylA) activity. [XylR, XylA] (Mus musculus) PubMed

 1786.

Replacement of an elusive C-terminal domains with a known tetrameric scaffold could potentially assist the expression of potassium channels. [potassium channel KcsA] (Mus musculus) PubMed

 1787.

Expression of the pstS gene is regulated by the carbon source but is not controlled by the PhoP regulator. [pstS, PhoP] (Mus musculus) PubMed

 1788.

These results suggest that ArfA is a new promoter-binding regulator for antibiotic production and for bldH expression in S. lividans (ArfA) (Mus musculus) PubMed

 1789.

The results uphold the premise that polyP and the C-terminal arginines are decisive elements in KcsA channel regulation[KcsA] (Mus musculus) PubMed

 1790.

Synthetic antigen-binding fragments (Fabs) were used as crystallographic chaperones to determine the structure of full-length KcsA at 3.8 A, as well as that of its isolated C-terminal domain at 2.6 A.[KcsA] (Mus musculus) PubMed

 1791.

The authors propose that selective permeation from the intracellular side primarily results from a large energy barrier blocking filter entry for Na(+) and Li(+) in the presence of K(+), not from a difference of binding affinity between ions. (Mus musculus) PubMed

 1792.

Data show that MiaB protein is a bifunctional system, involved in both thiolation and methylation of isopentenyl-adenosine (i(6)A) [MiaB]. (Mus musculus) PubMed

 1793.

MreB and actin display significantly different assembly properties despite high structural homology [MreB] (Mus musculus) PubMed

 1794.

X-ray structure of TrmE; the structural and biochemical studies presented here suggest how TrmE most likely directly participates in at least the first step of the cmnm modification reaction in the anticodon loop of certain tRNAs [TrmE] (Mus musculus) PubMed

 1795.

determined the crystal structure of the hetero-octameric (HisGS)4HisZ4 tmATPPRTase complex at 2.5 A resolution [HisGs, HIsZ] (Mus musculus) PubMed

 1796.

Results describe the crystal structure of Thermotoga maritima tRNase Z at 2.6-A resolution, and present a docking model with tRNA that suggests how tRNase Z may recognize the substrate tRNAs [tRNAse Z]. (Mus musculus) PubMed

 1797.

biophysical analysis of how IGP synthase excludes water to optimize ammonia transfer [IGP synthase, PDB 1GPW] (Mus musculus) PubMed

 1798.

domain orientation in free L11 shows limited similarity to that of ribosome-bound L11 in complex with elongation factor, EF-G [ribosomal protein L11] (Mus musculus) PubMed

 1799.

the crystal structure at 3.85 A resolution of the RNA component of Thermotoga maritima ribonuclease P [ribonuclease P, RNA component] (Mus musculus) PubMed

 1800.

Data describe the cloning, purification and characterization of HydE and HydG proteins from the thermophilic organism Thermotoga maritima [HydE and HydG]. (Mus musculus) PubMed

 1801.

Crystal structure of Hsp33 [Hsp33 or TM1394] (Mus musculus) PubMed

 1802.

Data support the idea that interactions of the DNA duplex template arm with the RecG protein are the major sites of binding and production of translocation [RecG] (Mus musculus) PubMed

 1803.

BglT employs a fully stepwise E1(cb) mechanism involving anionic transition states to catalyze the hydrolysis of glycosidic bonds, in contrast to all other currently characterized glycosidase families. (BglT, 6-phospho-beta-glucosidase) (Mus musculus) PubMed

 1804.

evolutionarily related family of aldolases distinct from the N-acetylneuraminate lyase (NAL) family [2-keto-3-deoxy-6-phosphogluconate aldolase] (Mus musculus) PubMed

 1805.

structural analysis of the complex reveals the presence of three binding-subsites, which explains why T. maritima invertase exhibits a higher affinity for raffinose than sucrose [invertase] (Mus musculus) PubMed

 1806.

crystal structure of a soluble FtsH construct that is functional in caseinolytic and ATPase assays[FtsH] (Mus musculus) PubMed

 1807.

endo-beta-1,4-D-galactanase gene of Thermotoga maritima was cloned and overexpressed in Escherichia coli [endo-beta-1,4-D-galactanase] (Mus musculus) PubMed

 1808.

investigation of the crystal structure of inorganic polyphosphate/ATP-NAD kinase, PPNK_THEMA, a protein from Thermotoga maritima [PPNK_THEMA] (Mus musculus) PubMed

 1809.

TM1367 crystal structure reveals unexpected similarities to members of the cyclophilin (peptidylprolyl isomerase) fold[ TM1367 ] (Mus musculus) PubMed

 1810.

crystal structures of the full-length Thermotoga maritima CorA in an apparent closed state and its isolated cytoplasmic domain at 3.9 A and 1.85 A resolution, respectively [CorA] (Mus musculus) PubMed

 1811.

the DnaA homolog (tmaDnaA) of Thermotoga maritima forms open complexes with the predicted origin region (tma-oriC) in vitro. TmaDnaA has a strong and specific affinity for ATP/ADP as well as for 12-mer repeating sequences within the tma-oriC [DnaA] (Mus musculus) PubMed

 1812.

The NMR structures of the unphosphorylated Thermotoga maritima protein TM1442 at pH 4.8 and of the phosphorylated TM1442 (TM1442-P). at pH 7.0 are presented, and a functional interaction of TM1442 with TM0733 is characterized (TM1442) (Mus musculus) PubMed

 1813.

determined a 2.9 angstrom resolution structure of CorA that reveals a pentameric cone-shaped protein; two potential regulatory metal binding sites are found in the N-terminal domain that bind both Mg2+ and Co2+ [CorA] (Mus musculus) PubMed

 1814.

This work describes the first direct observation of the interaction between P1 and P4 domains in CheA. (CheA) (Mus musculus) PubMed

 1815.

Results describe the structure of a histidine kinase (ThkA) complexed with a response regulator (TrrA) in the two-component regulatory system from hyperthermophile Thermotoga maritima [ThkA, TrrA]. (Mus musculus) PubMed

 1816.

Asp-52 and His-222 directly contribute the proton transfer of tRNase Z catalysis (tRNase Z). (Mus musculus) PubMed

 1817.

The PLP synthase holoenzyme consists of two subunits. [Pyridoxal-5-phosphate synthase] (Mus musculus) PubMed

 1818.

The crystal structure of TM1602 was determined to 2.3 A resolution using the MAD method. The final model includes a monomer (residues 3-174), one Ni2+ ion, one K+ ion, and 97 water molecules in the asymmetric unit [TM1602] (Mus musculus) PubMed

 1819.

The structures of hTK1 and of the Thermotoga maritima thymidine kinase (TmTK) in complex with the bisubstrate inhibitor TP4A, is reported. (Mus musculus) PubMed

 1820.

The crystal structure of a putative transcriptional regulator protein TM1030 from Thermotoga maritima, a hyperthermophilic bacterium, was determined by an unusual multi-wavelength anomalous dispersion method at 2.0 (Mus musculus) PubMed

 1821.

Thermodynamic properties calculated in the dynamic context of the protein structure provided new insight into the mechanism of glutamate dehydrogenase thermostabilization (glutamate dehydrogenase). (Mus musculus) PubMed

 1822.

Rates of methionine formation in the presence and absence of TM0269 and S-adenosylmethionine demonstrate that both TM0269 and S-adenosylmethionine are required for reactivation of the inactive cob(II)alamin form of TM0268 (TM0268 and TM0269). (Mus musculus) PubMed

 1823.

The conditions that regulate MreB's monomer-to-polymer assembly reaction, the critical concentrations of that reaction, the manner in which MreB uses nucleotides, its stability, and the structure of the assembled polymer, are characterized.[MreB] (Mus musculus) PubMed

 1824.

ATP-DnaA-oriC unwinding element complexes specifically bound the upper strand of single-stranded DUE[DnaA] (Mus musculus) PubMed

 1825.

functional switch of Tm HtrA is embedded in the sentinel of the helical lid in terms of substrate accessibility[High-temperature requirement A] (Mus musculus) PubMed

 1826.

analysis of structure-function relationships and gating mechanisms in the CorA Mg2+ transport system [CorA] (Mus musculus) PubMed

 1827.

recombinant protein, cloned from Thermotoga maritima genomic DNA, was overproduced in Esherichia coli and crystallized in 25%(v/v) PEG 4000, 100 mM NaCl and sodium citrate buffer pH 5.0 at 291 K [ folate-dependent tRNA methyltransferase] (Mus musculus) PubMed

 1828.

measurement of the conformational flexibility of the protein by hydrogen-deuterium exchange [GAPDH] (Mus musculus) PubMed

 1829.

HU bends DNA and constrains negative DNA supercoils in the presence of topoisomerase I (HU). (Mus musculus) PubMed

 1830.

Data indicate that the flexible arm of tRNase Z is not essential for pre-tRNA binding but affects the cleavage site selection: [tRNase Z] (Mus musculus) PubMed

 1831.

Thermotoga maritima XseA/B homologs TM1768 and TM1769 showed nuclease activity that is magnesium dependent and is inhibited by phosphate ions, which distinguish it from E. coli ExoVII (TM1768 and TM1769). (Mus musculus) PubMed

 1832.

the crystal structure of SecA bound to the SecY complex, with a maximum resolution of 4.5 angstrom (A), obtained for components from Thermotoga maritima [SecA; Sec Y] (Mus musculus) PubMed

 1833.

these findings suggest that the substrate specificity of TM0416p is likely to differ substantially from those of other D-tagatose 3-epimerase family enzymes.[TM0416p] (Mus musculus) PubMed

 1834.

findings indicate that the putative active site nucleophile is not required for FDTS catalysis, and no alternative nucleophilic residues capable of serving this function can be identified [flavin-dependent thymidylate synthase] (Mus musculus) PubMed

 1835.

Study found a new class of bifurcating [FeFe] hydrogenase in which the exergonic oxidation of ferredoxin is used to drive the unfavorable oxidation of NADH. New Gene: [FeFe] hydrogenase (Mus musculus) PubMed

 1836.

Study analyzed the biochemical properties of a TF:S7 complex from Thermotoga maritima and determined its crystal structure & obtained an atomic-level picture of a promiscuous chaperone in complex with a physiological substrate protein.[tig] (Mus musculus) PubMed

 1837.

Study reports the structure of the complex between the entire cytoplasmic portion of Thermotoga maritima class I HK853 and its cognate, RR468, as well as the structure of the isolated RR468, both free and BeF(3)(-) bound.[HK853, RR468] (Mus musculus) PubMed

 1838.

In this study, they characterized cbf11+ and cbf12+, the two CSL genes of Schizosaccharomyces pombe, in order to elucidate the CSL function in fungi. They provide evidence supporting their identity as genuine CSL genes. (Mus musculus) PubMed

 1839.

Flo8 and Mss11 bind indirectly to UAS2-1 of the STA1 promoter by interacting with Ste12 and Tec1 [STA1] (Mus musculus) PubMed

 1840.

In this article, we extend these findings by uncovering a role for H2B phosphorylation at serine 10 (Ser10) in another biological event that is associated with dramatic alterations in higher-order chromatin structure, meiosis [histone 2b] (Mus musculus) PubMed

 1841.

PIG-Y appeared to be directly associated with PIG-A, implying that PIG-Y is the key molecule that regulates GPI-GnT activity by binding directly to the catalytic subunit PIG-A. PIG-Y is probably homologous to yeast Eri1p, a component of GPI-GnT. [PIG-Y] (Mus musculus) PubMed

 1842.

The purification and characterization of the three Snf1-activating kinases (Sak1, Tos3, and Elm2) of Saccharomyces cerevisiae are reported.[Elm2] (Mus musculus) PubMed

 1843.

We demonstrate that polyprenol reductase preferentially acts on typical polyprenols with 13-18 isoprene residues but can reduce much longer polyprenols with even 32 isoprene residues (Mus musculus) PubMed

 1844.

Four active forms of CK2, composed of alphaalpha'betabeta', alpha(2)betabeta', alpha'(2)betabeta', and a free alpha'-subunit were isolated from wild-type yeast. (protein kinase CK2) (Mus musculus) PubMed

 1845.

novel biotin biosynthesis gene identified and characterized;results suggest that Bio6p acts in an unknown step of biotin synthesis before KAPA synthesis [B106] (Mus musculus) PubMed

 1846.

Raf60 is a component of the Rpd3 histone deacetylase complex that it is required for normal Rpd3 complex activity and repression of gene expression (Mus musculus) PubMed

 1847.

The dephosphorylation of gammaH2AX by the HTP-C is necessary for efficient recovery from the DNA damage checkpoint [H2AX histone] (Mus musculus) PubMed

 1848.

We found that strains deleted for either NAT3 or MDM20 displayed different growth rates and morphologies in specific stress conditions, demonstrating that the two NatB subunits have partly individual functions [natB] (Mus musculus) PubMed

 1849.

An analysis of the amino acid residues necessary for binding of YS11 to 18s rRNA in S. cerevisiae is presented.[YS11] (Mus musculus) PubMed

 1850.

crystal strycture of Geranylgeranyl-Diphosphate Synthase type III [GGPP3] (Mus musculus) PubMed

 1851.

The kinetics and thermodynamics of the alkaline and acid conformational transitions of a Lys 79 --> Ala/Asn 52 --> Gly (A79G52) variant of iso-1-cytochrome c are studied[iso-1-cytochrome c] (Mus musculus) PubMed

 1852.

Two classes of prohibitin dependent mutation (pbd1 and pbd2) were isolated and characterised. pbd1 mutant slightly extended lifespan, whereas in contrast, the pbd2 mutation resulted in a shortening in both the mean- and the maximum-lifespan. [Pbd1, Pbd2] (Mus musculus) PubMed

 1853.

Sequences in the N-terminal cytoplasmic domain of Saccharomyces cerevisiae maltose permease, Mal61, are required for vacuolar degradation but not glucose-induced internalization. [Mal61] (Mus musculus) PubMed

 1854.

These results indicate that the short-chain dehydrogenase-reductase-like Gly motif likely provides support to the overall structure of xylose reductase (XR), but it does not contribute directly to coenzyme binding in this XR. [xylose reductase] (Mus musculus) PubMed

 1855.

analysis of the mechanism of Rbp1p function [Rbp1p] (Mus musculus) PubMed

 1856.

TOR also regulates late stages of ribosome maturation in the nucleoplasm via the nuclear GTP-binding protein Nog1. [TOR] (Mus musculus) PubMed

 1857.

crystal structure of Saccharomyces cerevisiae eEF3, showing that it consists of an amino-terminal HEAT repeat domain, followed by a four-helix bundle and two ABC-type ATPase domains, with a chromodomain inserted in ABC2 [eEF3] (Mus musculus) PubMed

 1858.

PER1 encodes an evolutionary conserved component of the Glycosylphoshatidylinositol (GPI) anchor remodeling pathway, highlighting the close connection between the lipid remodeling of GPI and raft association of GPI-anchored proteins.[Phospholipase A2] (Mus musculus) PubMed

 1859.

These results support a eukaryotic stalk structure in which P1 proteins are internally located while P2 proteins are more external and accessible to interact with other cellular components. [Ribosomal phosphoprotein P1, P2] (Mus musculus) PubMed

 1860.

Comparison of 2D (15)N-HSQC spectra of IA(3) in water & in 23% 2,2,2-trifluoroethanol shows that individual residue cross peaks of IA(3) become more dispersed in TFE, indicating that it undergoes an unstructured to structured transition in TFE.[IA(3)] (Mus musculus) PubMed

 1861.

Although pol eta could accommodate large bulges and continue synthesis without obstruction, bulge structures in the template, but not in the primer, caused termination of the T7 DNA replication complex[T7 DNA polymerase ] (Mus musculus) PubMed

 1862.

These results support the existence of different components within the basic transcription complexes that antagonistically interact with the NC2 repressor.[Nc2 protein] (Mus musculus) PubMed

 1863.

Might compensate the function of enzymes that detoxify H(2)O(2). (Mpr1, an N-acetyltransferase [not the same as RPN11, a metalloproteinase sometimes known as Mpr1] (Mus musculus) PubMed

 1864.

A model that explains the role of multiple cyclin E/Sic1 degrons is provided by the findings that Fbw7 and Cdc4 dimerize, that Fbw7 dimerization enhances the turnover of a weakly associated cyclin E in vivo.[Fbw7] (Mus musculus) PubMed

 1865.

Study determined crystal structure of fatty acid synthase, which illuminates how this enzyme is initially activated and then carries out multiple steps of synthesis in each of six sterically isolated reaction chambers.[Alpha subunit of FAS] (Mus musculus) PubMed

 1866.

These results suggest that polyadenylated mRNA can enter P-bodies, and an mRNP complex including poly(A) mRNA, Pab1p, eIF4E, and eIF4G2 may represent a transition state during the process of mRNAs exchanging between P-bodies and translation.[EIF4E, EIF4G] (Mus musculus) PubMed

 1867.

AID action is transcription-dependent in yeast and that strong and transcription-dependent hypermutation and hyperrecombination are induced by AID if cells are deprived of THO. (Mus musculus) PubMed

 1868.

Hsp104 actively unfolds its polypeptide substrates during processing[HsP104 protein] (Mus musculus) PubMed

 1869.

Q72E-yeast VDAC1 requires three glutamate residues, located in two cytosolic loops, for the interaction of VDAC1 with RuR and subsequent protection against cell death[Vdac1] (Mus musculus) PubMed

 1870.

ADD66 encodes an approximately 30-kDa soluble, cytosolic protein and that the chymotrypsin-like activity of the proteasome is reduced in add66Delta mutants.[A1Pi] (Mus musculus) PubMed

 1871.

Gamma-glutamyltransferase (GGT) is involved in recycling cadmium-glutathione complex in vacuoles. (Mus musculus) PubMed

 1872.

The interaction between Bir1p and Sli15p is specifically involved in regulating septin dynamics during anaphase.[Septin] (Mus musculus) PubMed

 1873.

chaperones within distinct complexes can play unique roles during endoplasmic reticulum-associated degradation (ERAD), establishes a role for Sse1/Hsp110 in ERAD, and identifies Hsp110 as a target to lower cholesterol[ Hsp110, apoB29 and apoB48] (Mus musculus) PubMed

 1874.

Phosphatidylethanolamine and phosphatidylserine stimulate GTPase-activating protein (GAP) activity of Rga1p and Rga2p toward Cdc42p, whereas PI(4,5)P(2) inhibits it. [Rga1; Rga2] (Mus musculus) PubMed

 1875.

One of the differentially expressed genes, YBR174W, is required for optimal growth in synthetic medium.[YBR174W] (Mus musculus) PubMed

 1876.

A previously unrecognized function for the Saccharomyces cerevisiae Sad1-UNC-84 domain protein Mps3 in regulating telomere positioning in mitotic cells, is reported.[UNC-84] (Mus musculus) PubMed

 1877.

Role for the cell cycle-regulated protein kinase Dbf2p in promoting V-ATPase function and mediating sorbic acid stress tolerance.[Dbf2p, V-ATPase] (Mus musculus) PubMed

 1878.

in both yeast and amoebae, TM9 proteins (Dictyostelium Phg1a, b, and c; and S. cerevisiae Tmn1, 2 and 3) participate in the control of specific cellular functions in response to changing nutrient conditions (Mus musculus) PubMed

 1879.

Fpk1p/Fpk2p are upstream activating protein kinases for Lem3p-Dnf1p/Dnf2p. (Fpk1p and Fpk2p) (Mus musculus) PubMed

 1880.

confirms the important role of the N-terminal segment of cofilin in interactions with G-actin[G-actin] (Mus musculus) PubMed

 1881.

Pba3-Pba4 orchestrates formation of a specific type of proteasome, the first example of a trans-acting factor that controls assembly of alternative proteasomal complexes.[Pba3, Pba4] (Mus musculus) PubMed

 1882.

The structure of the Dmp1-Dmp2-alpha5 complex reveals how this chaperone functions in proteasome assembly and why it dissociates from proteasome precursors before the beta-rings are assembled.[Dmp1, Dmp2] (Mus musculus) PubMed

 1883.

the Fra-Grx complex is an intermediate between the production of mitochondrial Fe-S clusters and transcription of the iron regulon [Fra1-Fra2] (Mus musculus) PubMed

 1884.

results suggest that Myr1 is a novel factor linked to the secretory pathway and important cellular regulatory mechanisms [myr1] (Mus musculus) PubMed

 1885.

analysis of the key surfaces on p35/ARPC2 required for Arp2/3 complex-mediated actin assembly and cellular function [ARPC2] (Mus musculus) PubMed

 1886.

These results reveal a previously unknown ubiquitin-dependent mechanism for controlling the pre-mRNA splicing pathway.[ubiquitin] (Mus musculus) PubMed

 1887.

This work provides a mechanistic framework for investigating the toxicity of TDP-43 aggregation relevant to human disease.[TDP-43] (Mus musculus) PubMed

 1888.

Overexpression of DGK1 causes the appearance of phosphatidate-enriched membranes around the nucleus and leads to its expansion, without proliferating the cortical endoplasmic reticulum membrane[diacylglycerol kinase 1] (Mus musculus) PubMed

 1889.

The results of functional analyses demonstrated roles for Mpp6 in the surveillance of both pre-rRNA and pre-mRNAs and in the degradation of "cryptic" noncoding RNAs. (Mus musculus) PubMed

 1890.

Data show that Iqg1p interacts with three targets in Saccharomyces cerevisiae: myosin essential light chain (Mlc1p), calmodulin (Cmd1p) and the small GTPase Cdc42p [Iqgp1]. (Mus musculus) PubMed

 1891.

Structural dynamics increase with increasing Mg(2+) concentrations, enabling the enzyme to reach its active state[D135 ribozyme] (Mus musculus) PubMed

 1892.

Adaptation to H(2)O(2) treatment was demonstrated to occur when anaerobically grown wild-type cells were aerated for a short time that was reliant on the Yap1p and Skn7p transcription factors.[Yap1, Skn7p] (Mus musculus) PubMed

 1893.

Results identified yeast Rpl31, a component of the large ribosomal subunit, as a contact point of the ribosome-associated complex at the polypeptide tunnel exit [Rpl31]. (Mus musculus) PubMed

 1894.

structural comparison of dimethylallyltransferase (DMATase) in the complex with unliganded bacterial DMATase provides a molecular basis of ordered substrate binding by DMATase[dimethylallyltransferase] (Mus musculus) PubMed

 1895.

One contains glycosylated pro-alpha-factor, the second contains the GPI-anchored proteins Cwp2p, Ccw14p and Tos6p and the third is enriched with the hexose transporter, Hxt1p[tos6] (Mus musculus) PubMed

 1896.

DEAD-box proteins CYT-19, Mss116p, and Ded1p can achieve complete strand separation using a single ATP[CYT-19] (Mus musculus) PubMed

 1897.

Yeast PARK9 helps to protect cells from manganese toxicity, revealing a connection between Parkinson disease genetics (alpha-syn and PARK9) and an environmental risk factor (PARK9 and manganese).[PARK9] and [PARK1=alpha synuclein]. (Mus musculus) PubMed

 1898.

MSRA and MSRB helps to preserve the function of cellular FeS clusters from oxidative inactivation. [MSRB] (Mus musculus) PubMed

 1899.

These data support a model in which autophagy is negatively regulated by the Tap42-PP2A pathway.[PP2A] (Mus musculus) PubMed

 1900.

These findings provide the first evidence that NoCut is triggered by the interaction of acetylated chromatin with the passenger complex at the spindle midzone.[NoCut] (Mus musculus) PubMed

 1901.

Ubiquitination of histone H2B and methylations of histone H3 are required for the release of Cdc14 from nucleolar chromatin. [H3, H2B] (Mus musculus) PubMed

 1902.

Biophysical, structural and genetic studies presented here reveal that CDC26 stabilizes the structure of APC6, a core TPR protein required for APC integrity.[APC6] (Mus musculus) PubMed

 1903.

(Fra2 protein) Inclusion of Fra2 in the Grx3/4 iron-sulfur complex causes a change in the cluster stability and coordination environment. (Fra2 protein) (Mus musculus) PubMed

 1904.

PRD-4 is an ortholog of mammalian checkpoint kinase 2 (Chk2); expression of prd-4 is regulated by the circadian clock and, reciprocally, PRD-4 physically interacts with the clock component FRQ, promoting its phosphorylation [PRD-4] (Mus musculus) PubMed

 1905.

POD6 acts together with COT1 and is essential for polar cell extension in a kinesin/dynein-dependent manner in N. crassa.[Pod6, Cot1] (Mus musculus) PubMed

 1906.

(GPR-4):The involvement of a predicted G-protein-coupled receptor (GPCR), GPR-4, during growth and development in the presence of different carbon sources in N. crassa is investigated. (Mus musculus) PubMed

 1907.

The cellular distribution of catalase-2 and catalase-4 was determined: CAT2 and CAT4. (Mus musculus) PubMed

 1908.

In Neurospora, both nonhomologous integration pathways, MUS-52-dependent and MUS-52-independent, require MUS-53 (a homolog of human Lig4), which functions in the final step of nonhomologous end-joining. [Mus-53] (Mus musculus) PubMed

 1909.

cysteine residues of NADH:ubiquinone oxidoreductase 11.5kDa subunit are likely important to acquisition & stabilization of the correct conformation [NADH:ubiquinone oxidoreductase 11.5kDA subunit] (Mus musculus) PubMed

 1910.

identified QIP, a putative exonuclease, as a QDE-2-interacting protein; disruption of qip in Neurospora impaired gene silencing and siRNA accumulated, mostly in nicked duplex form [Qip protien] (Mus musculus) PubMed

 1911.

Clockswitch (csw-1), is required for clock function; its product localizes to the frq promoter, is required for proper frq expression, and has an impact on chromatin structure. (Mus musculus) PubMed

 1912.

Expression of the nde-3 gene is up-regulated in the late exponential growth phase of N. crassa.(Nde-3) (Mus musculus) PubMed

 1913.

Data indicate that RRG-1 controls vegetative cell integrity, hyperosmotic sensitivity, fungicide resistance, and protoperithecial development through regulation of the OS-4/OS-5/OS-2 MAPK pathway [RRG-1]. (Mus musculus) PubMed

 1914.

These results suggest that BiP and FKBP22 form a folding helper complex with a high chaperoning capacity in the endoplasmic reticulum of Neurospora crassa.[BiP, FKBP22] (Mus musculus) PubMed

 1915.

Results describe the CPC1 regulon, the ortholog of Saccharomyces cerevisiae GCN4, by profiling transcription in wild-type and cpc-1 mutant strains. (Mus musculus) PubMed

 1916.

The association of FKBP22 with the molecular chaperones and folding catalysts Grp170, alpha-subunit of glucosidase II, PDI, ERp38, and CyP23, is demonstrated. (Mus musculus) PubMed

 1917.

CAO-2 is the enzyme responsible for the oxidative cleavage of torulene in the neurosporaxanthin biosynthetic pathway [CAO-2] (Mus musculus) PubMed

 1918.

The subcellular location and traffic of two selected chitin synthases (CHS) from Neurospora crassa, CHS-3 and CHS-6, labeled with green fluorescent protein (GFP), were studied by high-resolution confocal laser scanning microscopy.[Spk, CHS 6] (Mus musculus) PubMed

 1919.

Several mixed detergent systems were analyzed for their ability to fold Neurospora mitochondrial porin.[Mitochondrial porin] (Mus musculus) PubMed

 1920.

These findings suggest that OS-2 MAP kinase(OS-2 Mitogen-Activated Protein Kinase) regulated the expression of cat-1 and cat-3 transcriptionally, and probably that of cat-3 posttranscriptionally. (Mus musculus) PubMed

 1921.

CYT-19 mediates ATP-dependent unfolding of both the native conformation and a long-lived misfolded conformation of a group I catalytic RNA with efficiencies that depend on the stabilities of the RNA species but not on specific structural features [CYT-19] (Mus musculus) PubMed

 1922.

These results suggest that OS-2 participates in the regulation of ccg-1 gene. (OS-2)(ccg-1) (Mus musculus) PubMed

 1923.

Meiotic Silencing by Unpaired DNA (MSUD), a mechanism that silences expression from unpaired DNA during meiosis, requires the dcl-1 (but not the dcl-2) gene for its function.[DCL-1] (Mus musculus) PubMed

 1924.

These data indicate that differential expression of FRQ isoforms is not required for temperature compensation but rather provides a means to fine-tune period length in response to ambient temperature.[FRQ] (Mus musculus) PubMed

 1925.

QDE-1 is enriched at the transgenic locus required to trigger post-transcriptional gene silencing (QDE-1). (Mus musculus) PubMed

 1926.

Studies show show that Neurospora U2 snRNP associated factor (U2AF65) binds RNA with low affinity and specificity, apparently evolving with its disappearing binding site [U2AF65] (Mus musculus) PubMed

 1927.

Genetic and molecular analysis of the temperature-sensitive mutant un-17 carrying a mutation in the gene encoding poly(A)-polymerase in Neurospora crassa (Mus musculus) PubMed

 1928.

Study concludes that the MID-1 protein plays a role in regulation of ion transport via Ca(2+) homeostasis and signaling. In the absence of normal ion transport activity, the mutant exhibits poorer growth. (Mus musculus) PubMed

 1929.

RHO-4 plays important roles in regulating cytoskeleton and are essential for hyphal tip growth. [Rho4] (Mus musculus) PubMed

 1930.

These results verify the role of Ncap conformational changes in gating the photic response of N. crassa and indicate that LOV-LOV homo- or heterodimerization may be a mechanism for regulating light-activated gene expression.[VVD] (Mus musculus) PubMed

 1931.

These data indicate a functional link between COT1 and MAPK signaling in regulating filamentous growth, hyphal fusion, and sexual development.[COT1, MAK1, MAK2] (Mus musculus) PubMed

 1932.

Study concludes that DNA methylation in Neurospora is mainly the result of a unidirectional pathway in which DIM-5 methylates histone H3K9 and then the DIM-2/HP1 complex recognizes the resulting trimethyl-H3K9 mark via the chromo domain of HP1.[HP1] (Mus musculus) PubMed

 1933.

RHO1/LRG1 function in parallel with COT1 in coordinating apical tip growth.[COT1, LRG1] (Mus musculus) PubMed

 1934.

Growth of basal hyphae is significantly reduced in mik-1, mek-1, and mak-1 deletion mutants on solid medium. [mik-1, mek-1, and mak-1] (Mus musculus) PubMed

 1935.

establish an unexpected plasticity to the Polyketide Synthases fold, unanticipated from structural studies of other members of this enzyme family[oxoalkylresorcylic acid synthase] (Mus musculus) PubMed

 1936.

The cyanide hydratase assembly is stabilized by two dyadic interactions between dimers across the one-start helical groove. [CHT, cyanide hydratase] (Mus musculus) PubMed

 1937.

The study indicates that the zinc transport proteins encoded by tzn1 and tzn2 are members of the zinc uptake system regulated by zinc status in N. crassa. New Gene: tzn1 (Mus musculus) PubMed

 1938.

T1hex-1 transcript and a variant splicing T2hex-1 transcript are up-regulated at alkaline pH (hex-1) (Mus musculus) PubMed

 1939.

strains with a mutation in the vivid (vvd) gene, previously shown to code for the photoreceptor involved in photo-adaptation, exhibit conidiation rhythms in constant illumination as well as in constant darkness [vvd] (Mus musculus) PubMed

 1940.

A PP1-impaired mutant showed increased H3S10p and selective reduction of methylation of H3K9 and DNA, similarly, amino acid substitutions of H3S10 abolished methylation of H3K9 and DNA [PP1, wild type] (Mus musculus) PubMed

 1941.

Data suggest that BEM46 plays a role in a signal transduction pathway involved in determining or maintaining cell type-specific polarity.[BEM46] (Mus musculus) PubMed

 1942.

Neurospora crassa SPA-2-GFP fusion protein was found at the apex of forming branches but not in septa, suggesting that it participates only in areas of tip growth. (Mus musculus) PubMed

 1943.

CaBP has an Mr of around 6 kDa. and one mole binds 2 moles of calcium and is partially inhibited by other divalent cations. [CaBP] (Mus musculus) PubMed

 1944.

Results suggest that DEAD-box proteins such as Mss116 and Cyt-19 function as RNA chaperones by virtue of their RNA-unwinding mechanism, which enables refolding of localized RNA regions or structures without globally disrupting RNA structure [Cyt-19]. (Mus musculus) PubMed

 1945.

The female and male fertility-1 (fmf-1) mutant of Neurospora crassa maps to a homologue of the Schizosaccharomyces pombe Ste11p (fmf-1). (Mus musculus) PubMed

 1946.

This is the first direct comparison of a monomeric Kinesin-3 with its dimeric full-length counterpart, and the kinetic changes observed here may also apply to other Kinesin-3 motors. (Mus musculus) PubMed

 1947.

Lah-1 and Lah-2 promote equitable Woronin body inheritance by providing a link to the cell cortex. [Lah-1, Lah-2] (Mus musculus) PubMed

 1948.

The rate of nuclear import of newly synthesized FRQ is progressively reduced in a phosphorylation-dependent manner, leading to an increase in the steady-state level of cytoplasmic FRQ[FRQ, no specific strain indicated] (Mus musculus) PubMed

 1949.

GPIT-2, a glycosylphosphatidylinositol (GPI)transamidase subunit, is required for the addition of GPI anchors onto GPI-anchored proteins. [GPIT-2] (Mus musculus) PubMed

 1950.

Leishmania eEF1B may help protect the parasite from lipid peroxidation [eEF1B] (Mus musculus) PubMed

 1951.

SMP-1, a member of a new family of small myristoylated proteins in kinetoplastid parasites, is targeted to the flagellum membrane [SMP-1] (Mus musculus) PubMed

 1952.

Leishmania major pteridine reductase is inhibited by 2,4,6-triaminoquinazoline, as shown by x-ray crystallography (Mus musculus) PubMed

 1953.

LmPOT1 is a polyamine permease from the protozoan parasite Leishmania major [LmPOT1] (Mus musculus) PubMed

 1954.

The expression and characterization of an ascorbate peroxidase from L. major is reported.[APX] (Mus musculus) PubMed

 1955.

identification and characterization of MRK1, an essential, putative MEK kinase [MRK1] (Mus musculus) PubMed

 1956.

identifiction and functional characterization of PEX19; evidence provided that PEX19 associates with other PEX membrane proteins [PEX19] (Mus musculus) PubMed

 1957.

molecular characterization of LRNase HIIC; it is essential for the survival of the parasite [LRNase HIIC] (Mus musculus) PubMed

 1958.

The Leishmania major mucolipin-like A and B genes (lmmlA and lmmlB) encode two proteins of 776 and 590 amino acids, respectively, and may be classified among the mucolipins family [transient receptors potential mucolipin (TRPML). [lmmlA], [lmmlB] (Mus musculus) PubMed

 1959.

results demonstrate that SCA1 encodes a sc-D-ArapT and provide the first example of heterologous expression of a D-ArapT gene [SCA1] (Mus musculus) PubMed

 1960.

The crystal structure of L. major GLO1 reveals differences in active site architecture to both human GLO1 and the nickel-dependent Escherichia coli GLO1.(GLO1) (Mus musculus) PubMed

 1961.

preliminary X ray structure [glyoxalase I] (Mus musculus) PubMed

 1962.

determination of the three-dimensional structure of the Lmaj006129AAA at 1.6 angstroms, encompassing residues 7-163 [Lmaj006129AAA] (Mus musculus) PubMed

 1963.

The isolation and characterization of phosphodiesterase A (PDEA), phosphodiesterase B1 (PDEB1), and phosphodiesterase B2 (PDEB2) are reported. [PDEA; PDEB1; PDEB2] (Mus musculus) PubMed

 1964.

genetic analysis and characterization of Leishmania major UDP-glucose pyrophosphorylase (Mus musculus) PubMed

 1965.

first report of a metalloid (antimonate) reductase (ACR2) with a bifunctional role in protein tyrosine phosphatase activity to dephosphorylate phosphotyrosine residues in leishmanial proteins [ACR2] (Mus musculus) PubMed

 1966.

analysis of Leishmania major surface metalloprotease GP63 (leishmanolysin) [GP63] (Mus musculus) PubMed

 1967.

RIC1 is a novel form of the F1 ATP synthase alpha-subunit that acts as the major energy transducer for tRNA import [RIC1] (Mus musculus) PubMed

 1968.

Overexpression of histone H1 delays parasite cell-cycle progression (histone H1) (Mus musculus) PubMed

 1969.

Over-expression of the active pyroglutamyl peptidase I (PPI), but not inactive PPI, in L. major impaired differentiation from the procyclic promastigote to the infective metacyclic promastigote. [pyroglutamyl peptidase I] (Mus musculus) PubMed

 1970.

intracellular localization of PRP1; mechanism of pentamidine resistance mediated by PRP1 is proposed [PRP1] (Mus musculus) PubMed

 1971.

Shuttle mutatgenesis as a source of reagents for targeted disruption of RNA polymerase III (RPC2) in L. major is reported.[RPC2] (Mus musculus) PubMed

 1972.

Kin13-2 localizes essentially to the flagellum, and its overexpression produces flagellar shortening and knockdown yields long flagella. [Kin13-2] (Mus musculus) PubMed

 1973.

These results taken together suggest that Leishmania LmAQP1 has multiple physiological roles, being involved in solute transport, volume regulation and osmotaxis.[AQP1] (Mus musculus) PubMed

 1974.

Reported here are the kinetic characterization of the LmjPDEB1 (phosphodiesterase)catalytic domain and its crystal structure as a complex with 3-isobutyl-1-methylxanthine (IBMX) at 1.55 A resolution. [PDEB1] (Mus musculus) PubMed

 1975.

Functional characterization of recombinant and native LmPEX7 revealed that this receptor bound the PTS2 protein fructose-1,6-bisphosphate aldolase.[PEX7] (Mus musculus) PubMed

 1976.

Thymidine kinase (TK1) was identified and role in flagellum formation, promastigote shape and growth, and virulence in mouse macrophages demonstrated. [TK1] (Mus musculus) PubMed

 1977.

The results of cytochrome c binding, compound I formation rate and activity assay suggested that Trp208 in LmAPX was essential for electron transfer from cytochrome c to heme ferryl but was not indispensable for ascorbate oxidation.[Ascorbate peroxidase] (Mus musculus) PubMed

 1978.

Leishmania trypanothione synthetase-amidase structure reveals a basis for regulation of conflicting synthetic and hydrolytic activities [TSA, trypanothione synthetase-amidase] (Mus musculus) PubMed

 1979.

shows the essentiality of the topS gene encoding the L. major DNA topoisomerase IB small subunit [DNA topoisomerase IB small subunit] (Mus musculus) PubMed

 1980.

Lmaj3'NT/NU may constitute a new important compound of the L. major purine scavenging pathway and could be involved in sandfly parasite survival and colonization. (Lmaj3'NT/NU) (Mus musculus) PubMed

 1981.

The cloning of ORC1 from L. major, and the analysis of its expression in L. major promastigotes were reported. (Mus musculus) PubMed

 1982.

The kinetoplastid Leishmania major Selenophosphate synthetase genes were cloned and the protein overexpressed and purified to apparent homogeneity. (Mus musculus) PubMed

 1983.

overexpression of LmAPX, an ascorbate peroxidase, caused depletion of the mitochondrial ROS burden and conferred a protection against mitochondrial cardiolipin oxidation and increased tolerance to H2O2 [LmAPX] (Mus musculus) PubMed

 1984.

This is the first report where metalloid and glycerol transport can be dissected by a single mutation at the extracellular pore entry of LmAQP1 channel.(LmAQP1) (Mus musculus) PubMed

 1985.

certain LACK-altered peptide ligands are able to induce T cell responses with a protective phenotype in an infectious disease such as leishmaniasis.[LACK] (Mus musculus) PubMed

 1986.

ATG12 localized in part to ATG8-containing puncta, suggestive of a functional ATG5-ATG12 conjugation pathway in the parasite.[Atg12] (Mus musculus) PubMed

 1987.

Myosin XXI expression was more predominant in the promastigote stage where it was preferentially localized in the proximal region of the flagellum.[Myosin XXI] (Mus musculus) PubMed

 1988.

Kinetic analysis shows a novel role of residue D70 in the excision rate of 3'-blocking ends by the class II AP endonuclease LMAP (LMAP). (Mus musculus) PubMed

 1989.

LmaNT3 and LmaNT4 are nucleobase/proton symporters;LmaNT3 functions optimally at neutral pH and LmaNT4 at low pH[LMANT3 AND LMANT4] (Mus musculus) PubMed

 1990.

Results suggest a role for mammalian and parasite casein kinase 1alpha in regulating IFNAR1 stability and type I IFN signaling. (Mus musculus) PubMed

 1991.

structure of the La motif from the Trypanosoma brucei La protein to 1.6 A resolution [La protein] (Mus musculus) PubMed

 1992.

TbRAB4 is involved in regulation of fluid-phase traffic to the lysosome in T. brucei but not in receptor-mediated endocytosis or recycling [Rab4] (Mus musculus) PubMed

 1993.

Results identify a subunit of a tRNA processing complex (T. brucei MT40 , which is a putative methyltransferase and a homolog of Saccharomyces cerevisiae Gcd14[MT40] (Mus musculus) PubMed

 1994.

Data suggest that cathepsin B (tbcatB), but not rhodesain, is essential for T. brucei survival in culture and is the most likely target of the diazomethane protease inhibitor Z-Phe-Ala-CHN(2) in T. brucei [tbcatB]. (Mus musculus) PubMed

 1995.

arginine 735 is essential for RNA interference (argonaute 1) (Mus musculus) PubMed

 1996.

Results describe a novel protein kinase, TbECK1, and the regulatory function of its long C-terminal extension [ECK1]. (Mus musculus) PubMed

 1997.

X-ray diffraction analysis of farnesyl diphosphate synthase from Trypanosoma brucei [Farnesyl diphosphate synthase (FPPS)] (Mus musculus) PubMed

 1998.

Results report the crystal structure of the catalytic domain of Trypanosoma brucei RNA editing ligase 1 (TbREL1) at 1.2 A resolution, in complex with ATP and magnesium [TbREL1]. (Mus musculus) PubMed

 1999.

role for TbTRF4 in transcription performed by all three nuclear RNA polymerases (Mus musculus) PubMed

 2000.

Rab5A and Rab5B are required for endocytosis in trypanosomes. [Rab5A and Rab5B proteins] (Mus musculus) PubMed

 2001.

MRP1 and MRP2 are not essential for RNA editing but may have a regulatory role in the editing of specific transcripts and other RNA processing activities [MRP1 (gBP21) and MRP2 (gBP25)] (Mus musculus) PubMed

 2002.

histone H3 variant is enriched at telomeres in Trypanosoma brucei [histone H3] (Mus musculus) PubMed

 2003.

SNIP is part of an organized nucleoplasmic machinery responsible for processing of SL RNA [SNIP exonuclease] (Mus musculus) PubMed

 2004.

KU80 may have a role in telomere length regulation in Trypanosoma brucei (KU80). (Mus musculus) PubMed

 2005.

Glycosome provides protection of trypanosomes from the dangerous design of glycolysis. (PEX14 AND hexokinase AND phosphofructokinase). (Mus musculus) PubMed

 2006.

NOPP44/46 is required for formation of the large ribosomal subunit in Trypanosoma brucei (Mus musculus) PubMed

 2007.

over-expression caused two-fold down regulation of cytochrome oxidase subunit IV, and cytochrome c1 protein and a four-fold up-regulation of GPEET procyclin in the procyclic form. [Aox, alternative oxidase] (Mus musculus) PubMed

 2008.

ARL1 is essential for viability in T. brucei bloodstream parasites (ARL1). (Mus musculus) PubMed

 2009.

FRDm1 is involved in the maintenance of the redox balance in the mitochondrion, as proposed for the ancestral soluble FRD presumably present in primitive anaerobic cells [FRDm1 fumarate reductase] (Mus musculus) PubMed

 2010.

kinetics for the cruzain catalyzed hydrolysis and structural examination for rational drug design (cruzain) (Mus musculus) PubMed

 2011.

TbMP42 contributes both endo- and exoribonuclease activity to the RNA editing reaction cycle [TbMP42] (Mus musculus) PubMed

 2012.

required for accurate and efficient cytokinesis but not for exit from mitosis. [MOB1-A, MOB1-B] (Mus musculus) PubMed

 2013.

results show that degradation of polyadenylated RNAs in T. brucei mitochondria can occur through a unique mechanism that requires the polymerization of UTP into RNAs, presumably by the RET1 TUTase [RET1] (Mus musculus) PubMed

 2014.

TbLRTP suppresses basal body replication and subsequent flagellar biogenesis and plays a critical role for the LRTP family of proteins in the control of the cell cycle. (Mus musculus) PubMed

 2015.

x-ray crystallographic analysis of Trypanosoma brucei prostaglandin H2 reductase [TbPGFS] (Mus musculus) PubMed

 2016.

TbMBAP1 is essential for both incoming and recycling membrane traffic.[TbMBAP1] (Mus musculus) PubMed

 2017.

TbRAB11 controls recycling and is essential in both life stages of T. brucei but its primary role is subject to developmental variation. (Mus musculus) PubMed

 2018.

identifiction and functional characterization of PEX19; findings show that show that knockdown of PEX19 in results in reduced growth and a glycosome biogenesis defect [PEX19] (Mus musculus) PubMed

 2019.

Results suggest that Trypanosoma brucei TTAGGG repeat-binding factor (tbTRF), like vertebrate TRF2, is essential for telomere end protection. (Mus musculus) PubMed

 2020.

The T. brucei ARL1 protein is expressed only in the mammalian bloodstream form of the parasite, in which it is localized to the Golgi apparatus (ARL1 protein) (Mus musculus) PubMed

 2021.

findings show that genetic ablation of TbZFP1 compromises repositioning of the mitochondrial genome, a specific event in the strictly regulated differentiation programme [ZFP1] (Mus musculus) PubMed

 2022.

the TRF4/SNAP(c)/TFIIA complex binds specifically to the SL RNA gene promoter upstream sequence element and is absolutely essential for spliced-leader RNA gene transcription in vitro [TRF4, SNAP(c), TFIIA] (Mus musculus) PubMed

 2023.

TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression [tSNAP42, TBP] (Mus musculus) PubMed

 2024.

CBF5 has a role in stabilization of small nucleolar RNAs of the H/ACA-like family [CBF5] (Mus musculus) PubMed

 2025.

Two splicing factors (Prp31 and Prp43) were found to be essential for both trans- and cis-splicing pathways, suggesting that splicing factors are shared by these two reactions. [Prp31, prp43] (Mus musculus) PubMed

 2026.

DMC1 is transcribed in the bloodstream stage where the gene can be mutated by reverse genetic disruption; mutation does not result in detectable alterations in DNA repair, recombination or antigenic variation efficiency in this life cycle stage [DMC1] (Mus musculus) PubMed

 2027.

These results indicate that the cellular distribution of trypanosome lytic factor (TLF) is influenced by Serum resistance-associated protein (SRA) expression and may directly determine the organism's susceptibility to TLF. (Mus musculus) PubMed

 2028.

The T.brucei TFIIB(like) protein localizes to the nucleus, specifically binds to the spliced leader RNA (SLRNA) promoter, interacts with RNA polymerase II, and is required for SLRNA transcription [TFIIB-like] (Mus musculus) PubMed

 2029.

The observation that both PEX5 and PEX7 are essential for the viability of the parasite indicates that the respective branches of the glycosome-import pathway in which each receptor acts might be interesting drug targets.[PEX7] (Mus musculus) PubMed

 2030.

TbcatB protein is a parasitic cysteine protease with a role in protein degradation and iron acquisition (Mus musculus) PubMed

 2031.

the complement-binding protein gene is deleted from the genome of Western African strains of monkeypox virus (Mus musculus) PubMed

 2032.

the RPO132 subunit of the RNA polymerase has a role in transcription elongation [RPO132] (Mus musculus) PubMed

 2033.

RING protein p28 can mediate the formation of polyubiquitin conjugates; p28 is ubiquitinated in vivo and ubiquitin colocalizes with p28 to virus factories independently of an intact RING domain [RING protein p28] (Mus musculus) PubMed

 2034.

cloned and sequenced the VGF gene of vaccinia virus strain Tian Tap [virus growth factor, VGF] (Mus musculus) PubMed

 2035.

data suggest that correct temporal expression of the VV I7L cysteine proteinase is required for core protein maturation, virion assembly and production of infectious progeny [I7L] (Mus musculus) PubMed

 2036.

H2 and A28 are the only proteins presently known to be specifically required for vaccinia virus entry and are likely components of a fusion complex. (H2 protein) (Mus musculus) PubMed

 2037.

required for vaccinia virion morphogeneis (J1R protein) (Mus musculus) PubMed

 2038.

important role of E3L in vaccinia virus pathogenesis involves modulating expression of host cellular genes at the transcriptional level [E3L] (Mus musculus) PubMed

 2039.

mapped complement control protein domains of VCP important for its cofactor activities, decay-accelerating activities & binding to target proteins; results show the entire length of the protein is required for VCP's various functional activities [VCP] (Mus musculus) PubMed

 2040.

Vaccinia virus F1L expression during infection inhibits apoptosis and interferes with the activation of Bak. (F1L) (Mus musculus) PubMed

 2041.

results suggest that protein disulphide isomerases may be involved in reorganization of disulfide bonds within the L1R protein [L1R] (Mus musculus) PubMed

 2042.

Atherosclerosis was induced by a high-fat diet, and Vaccinia virus complement control protein was injected once per week after 8 weeks, leading to a reduction of athersclerosis [Vaccinia virus complement control protein] (Mus musculus) PubMed

 2043.

Vaccinia virus F1L uses a specific, BH3-like domain to bind and inhibit Bak at the mitochondria. (F1L) (Mus musculus) PubMed

 2044.

Two vaccinia open reading frames were confirmed as being expressed as novel proteins: E6R and L3L. [E6R, L3L] (Mus musculus) PubMed

 2045.

The model supports biochemical evidence that VP39 functions as a processivity factor by partially enclosing the RNA primer at the heterodimer interface.[polyadenylate polymerase] (Mus musculus) PubMed

 2046.

B14 is an intracellular protein that is non-essential for virus replication in cell culture but contributes to virus virulence in vivo and affects the host response to infection. [B14] (Mus musculus) PubMed

 2047.

Vaccinia virus kelch protein A55 affects virus cytopathic effect in cell culture and virulence in murine intradermal infection model [A55] (Mus musculus) PubMed

 2048.

our results provide direct evidence that G3L is an essential component of the vaccinia virus fusion complex [G3L] (Mus musculus) PubMed

 2049.

In 293T cells, VV apparently utilizes its M2L protein to interfere with a step (s) that would otherwise enable ERK2 phosphorylation and the consequential activation of an NF-kappaBeta response. [M2L] (Mus musculus) PubMed

 2050.

These results point to the transmembrane domain of B5 as the major determinant of the A33-B5 interaction and demonstrate that protein-protein interactions are crucial in determining the composition of the virus envelope. [A33, B5] (Mus musculus) PubMed

 2051.

despite the structural relationships of L1 and F9, the two proteins have distinct functions in assembly and entry, respectively[L1 and F9] (Mus musculus) PubMed

 2052.

G9 is the sixth that has been shown to be required for entry and membrane fusion[ G9 protein] (Mus musculus) PubMed

 2053.

Deletions in the Z-DNA- or dsRNA-binding domains of E3L led to activation of signal transduction cascades and up-regulation of host gene expression, with many genes involved in the inflammatory response.[E3L] (Mus musculus) PubMed

 2054.

Multimerization of D5 protein (ATpase) and enzymatic activity are necessary to support DNA replication. [D5] (Mus musculus) PubMed

 2055.

This is the first structure of a virus-encoded tumour necrosis factor receptor (TNFR).[CrmE] (Mus musculus) PubMed

 2056.

The crystal structure of the complex between Fab-7D11 and L1 reveals the basis for the conformation-specific binding as recognition of a discontinuous epitope containing two loops that are held together by a disulfide bond. [L1 protein] (Mus musculus) PubMed

 2057.

purified recombinant VACV D9 fusion protein also decaps mRNA and that this activity was abolished by point mutations in the Nudix hydrolase motif.[D9] (Mus musculus) PubMed

 2058.

vaccinia virus mRNA cap N7 methyl-transferase was originally an RNA cap 2'O-MT that has evolved to a catalytically inactive form retained for D1 stabilisation and MT activity enhancement through an allosteric mechanism [mRNA cap N7 methyl-transferase] (Mus musculus) PubMed

 2059.

G6R protein, a member of the NlpC/P60 superfamily, in involved in virulence in mice but not replication in cell culture. [G6R] (Mus musculus) PubMed

 2060.

a new function for VCP that may be important for poxvirus pathogenesis and impact immune responses to VACV-based vaccines [complement control protein (VCP)] (Mus musculus) PubMed

 2061.

The 68k ankyrin-like protein (68k-ank)interacts with S-phase kinase-associated protein 1a (Skp1a), a part of the SCF ubiquitin ligase complex and co-immunoprecipitated with components of the endogenous, mammalian SCF ubiquitin ligase. [68k-ank] (Mus musculus) PubMed

 2062.

Results identify a new vaccinia IMV envelope protein, WR53.5, that mediates cell adhesion and is important for virus virulence in vivo [WR53.5]. (Mus musculus) PubMed

 2063.

The SPI-3/A56 complex on the infected cell surface therefore appears to reduce the entry of virions into infected cells.[A56] (Mus musculus) PubMed

 2064.

These data indicate that C16 diminishes the immune response and is an intracellular immunomodulator. [C16] (Mus musculus) PubMed

 2065.

Vaccinia virus L1 binds to cell surfaces and blocks virus binding and entry independently of glycosaminoglycans (Mus musculus) PubMed

 2066.

the dimeric quaternary structure of VH1 is essential for specific recognition of activated STAT1, which prevents its nuclear translocation, thus blocking interferon-gamma signal transduction and antiviral response [VH1] (Mus musculus) PubMed

 2067.

A34 is required to recruit B5 into the extracellular enveloped virus (EEV) membrane and B5 acts as a molecular switch to control EEV membrane rupture upon exposure to glycosaminoglycans.[B5] (Mus musculus) PubMed

 2068.

68-kDa ankyrin-like protein is an essential factor for DNA replication and completion of the MVA intracellular life cycle. [68k-ank] (Mus musculus) PubMed

 2069.

our data show that variola virus IL-18BP prevents IL-18 from binding to IL-18R by interacting with three residues that are part of the binding site for hIL-18Ralpha. [IL-18 binding protein] (Mus musculus) PubMed

 2070.

Smallpox inhibitor of complement enzymes is a virulence factor that binds to a variety of cell types and inhibits complement activation at the C3 convertase step with equal or greater efficiency than that of the related host regulators. [SPICE] (Mus musculus) PubMed

 2071.

Elimination of three heparin binding sites of SPICE protein severely decreases but does not eliminate glycosaminoglycan binding; complement regulatory sites overlap with each of the three heparin binding motifs. [SPICE protein] (Mus musculus) PubMed

 2072.

Cleavage by resolvase was also tightly coupled at symmetrical positions across the junction, and coupling required the complete Holliday junction structure[ resolvase] (Mus musculus) PubMed

 2073.

upregulation of these classic macrophage-related proinflammatory cytokine markers following infection of myeloid cells with the M141-knockout MYXV is mediated via the rapid activation of the cellular NF-kappaB pathway.[M141] (Mus musculus) PubMed

 2074.

The authors report that M-T5 can bind Akt and the host SCF complex (via Skp1) simultaneously in myxoma virus-infected cells. (Mus musculus) PubMed

 2075.

Results report the crystal structure of a viral FLIP, MC159, at 1.2 Angstroms resolution [MC159]. (Mus musculus) PubMed

 2076.

Transgenic expression of viral FLIP MC159 specifically blocks apoptosis and programmed necrosis induced by multiple death receptors but does not interfere with other essential lymphocyte functions [MC159] (Mus musculus) PubMed

 2077.

The MC160 protein of Molluscum contagiosum virus utilizes at least two distinct mechanisms for impeding NF-kappaB activation, association with Hsp90 to result in IKK1 protein degradation or interaction with procaspase-8.[MC160] (Mus musculus) PubMed

 2078.

proteomic studies show an association of ICP27 with the cellular translation initiation factors poly A binding protein, eukaryotic initiation factor 3, and eukaryotic initiation factor 4G in infected cells [ICP27] (Mus musculus) PubMed

 2079.

The direct interaction in vitro and in infected cells of ICP27 and ICP8. (Mus musculus) PubMed

 2080.

regulates eIF-2alpha phosphorylation and antagonizes PKR and PERK during productive infections [gamma(1)34.5 protein] (Mus musculus) PubMed

 2081.

cloning, sequencing, and characterization of a transcript immediately upstream of latency associated transcript; designated UOL [UOL] (Mus musculus) PubMed

 2082.

Herpes simplex virus type 1 (HSV-1) protein ICP27 interacts with the cellular export adaptor protein Aly/REF and the viral RNAs to which it binds are exported via the TAP/NXF1 export receptor.[ICP27] (Mus musculus) PubMed

 2083.

found that ICP27 enhances VP16 expression primarily by increasing the translational efficiency of VP16 mRNA [ICP27] [VP16] (Mus musculus) PubMed

 2084.

nucleolar localization of the viral protein ICP0 of herpes simplex virus type 1. (ICP0} (Mus musculus) PubMed

 2085.

requirement of ICP22 and the U(L)13 protein kinase in the posttranslational modification of RNA POL II (ICP22) (Mus musculus) PubMed

 2086.

REVIEW: ICP27 functions primarily at the post-transcriptional level in inhibiting precursor mRNA splicing and in promoting nuclear export of viral transcripts [ICP27] (Mus musculus) PubMed

 2087.

This prostein accumulates in cells infected with the mutant lacking the gene encoding ICP22 mediated the phosphorylation of histone deacetylase. (ICP22) (Mus musculus) PubMed

 2088.

These results indicate that the protein kinase activity of UL13 plays a role in viral replication in cell culture, but the activity is not essential for the optimal expression of UL41 and ICP0 [ICP0] (Mus musculus) PubMed

 2089.

triplet repeats in the central domain of the gamma134.5 protein of Herpes simplex virus 1 facilitate virus egress [gamma134.5 protein] (Mus musculus) PubMed

 2090.

baculovirus antiapoptosis gene can efficiently substitute for the LAT in enhancing the HSV-1 reactivation phenotype (Mus musculus) PubMed

 2091.

ICP0 targets USP7 for ubiquitination and proteasome-dependent degradation; concluded that USP7-mediated stabilization of ICP0 is dominant over ICP0-induced degradation of USP7 during productive HSV-1 infection [ICPO] (Mus musculus) PubMed

 2092.

a function encoded by the LAT gene increases the amount of dimethyl lysine 9 form of histone H3 or heterochromatin and reduces the amount of dimethyl lysine 4 form of histone H3 on viral lytic-gene promoters.(latency-associated transcript gene product) (Mus musculus) PubMed

 2093.

(latency-associated transcript) locus regulates the frequency of encephalitis in male or female mice. (Latency associated protein) (Mus musculus) PubMed

 2094.

Data show that the formation of superhelical ICP8-single stranded DNA filaments is required for annealing [ICP8]. (Mus musculus) PubMed

 2095.

observed that a decrease in both latency-associated transcript (LAT) enhancer histone H3 acetylation and LAT RNA abundance occurs prior to an increase in acetylation, or transcriptional permissiveness, at the ICP0 promoter [LAT, ICP0] (Mus musculus) PubMed

 2096.

VP16 was acquired prior to primary envelopment of the virus at the inner nuclear membrane [VP16] (Mus musculus) PubMed

 2097.

findings show that a function of the stable 2-kb LAT intron is to protect cells from cold-induced stress and that this may be mediated via Hsp70 [LAT] (Mus musculus) PubMed

 2098.

complement ICP0- viruses may lead to the identification of cellular activities that are important for reactivation from neuronal latency [ ICP0] (Mus musculus) PubMed

 2099.

VP16 and ICP0 stimulate viral gene expression at least in part by counteracting this innate antiviral defence mechanism.[VP16, ICP0] (Mus musculus) PubMed

 2100.

U(S)3 protein kinase blocks histone deacetylation by a mechanism distinct from that of ICP0.(ICP0) (Mus musculus) PubMed

 2101.

Promyelocytic leukemia protein contributes to a cellular antiviral repression mechanism that is countered by the activity of ICP0. (Mus musculus) PubMed

 2102.

The nucleocytoplasmic distribution of the LAT (latency-associated transcripts) exon RNA and its related function may be influenced by the differentiation state of cells. [LAT] (Mus musculus) PubMed

 2103.

LATs might be involved in the maintenance of HSV-1 latency through the posttranscriptional regulation of ICP0 in order to inhibit expression of this potent activator of gene expression during latency [ICP0] (Mus musculus) PubMed

 2104.

findings provide new data demonstrating that anterior corneal keratocytes become infected and express ICP0 during acute HSV-1 infection (Mus musculus) PubMed

 2105.

virion-specific differences in ICP22- viruses add a new level of complexity to the functional analysis of this immediate-early viral regulatory protein [ICP22] (Mus musculus) PubMed

 2106.

data indicate that the regulation of expression and processing of LAT RNA within the mouse is highly cell-type specific and occurs in the absence of other viral cis- and trans-acting factors [LAT] (Mus musculus) PubMed

 2107.

ICP27 is essential for IEX-1 mRNA stabilization whereas virion host shut plays little if any role[ICP27] (Mus musculus) PubMed

 2108.

HSV-1 LAT decreases the level of CGRP in trigeminal neurons [LAT PROTEIN, HSV1] (Mus musculus) PubMed

 2109.

DNA ligase IV/XRCC4 serves an important role in the replication cycle of herpes viruses [DNA ligase IV and XRCC4 ] (Mus musculus) PubMed

 2110.

the highly concentrated LANA-1, anchored to the host genome in the nuclear foci of latently infected cells and replicated through each cell generation, may function as "epigenetic modifier" (Mus musculus) PubMed

 2111.

the N terminus of VP5 and the alpha helices embedded in this domain, as in the capsid shell proteins of some double-stranded DNA phages, are a key regulator of shell accretion and stabilization.[VP5] (Mus musculus) PubMed

 2112.

LAT blocks two biochemical hallmarks of apoptosis, caspase 3 cleavage and DNA laddering, in the absence of other HSV-1 gene products.[LAT] (Mus musculus) PubMed

 2113.

The results show that the cytoplasmic localization of ICP0 and ICP4 is a prerequisite for the assembly of these proteins into viral particles and ICP27 plays a role in determining the composition of HSV-1 virions.[ICP27, ICP0, ICP4] (Mus musculus) PubMed

 2114.

Study confirms that ICP27 stimulates translation of VP16 mRNA as well as an additional HSV-1 late ICP5 mRNA.[ICP27] (Mus musculus) PubMed

 2115.

Viral immediate-early protein ICP27 plays a role in inhibiting interferon I signaling by downregulating STAT-1 phosphorylation and in preventing the accumulation of STAT-1 in the nucleus. [ICP27] (Mus musculus) PubMed

 2116.

2 LAT-specific small RNAs in the first 1.5 kb of LAT (apoptosis-inhibiting region). They have extensive secondary structure & a stem-loop structure & can base pair with the ICP4 mRNA. They may play a role in the latency-reactivation cycle. LAT. (Mus musculus) PubMed

 2117.

Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16.[ICP6 protein, HSV] (Mus musculus) PubMed

 2118.

nuclear localization signal may be involved in transport of VP1-2 early in infection or to late assembly sites within the nucleus or, considering the potential existence of VP1-2 cleavage products[VP1-2] (Mus musculus) PubMed

 2119.

Based on these results, the authors conclude that ICP27 has two distinct effects on the transfected gC gene: it (i) stimulates mRNA accumulation and (ii) promotes the retention of an intron.[ICP27] (Mus musculus) PubMed

 2120.

Herpes simplex virus-1 infected cell protein 27 (HSV-1 ICP27), represses NF-kappaB activity through binding to inhibitor of kappaB (IkappaBalpha), blocking phosphorylation and ubiquitination of IkappaBalpha, and stabilizing IkappaBalpha (ICP27). (Mus musculus) PubMed

 2121.

HSV-1 expresses at least two primary miRNA precursors (from LAT) in latently infected neurons that may facilitate the establishment and maintenance of viral latency by post-transcriptionally regulating viral gene expression[LAT] (Mus musculus) PubMed

 2122.

have implications on the role of base excision repair in viral genome maintenance during lytic replication and reactivation from latency[ 5'-deoxyribose phosphate lyase] (Mus musculus) PubMed

 2123.

Induction of cellular stress overcomes the requirement of herpes simplex virus type 1 for immediate-early protein ICP0 and reactivates expression from quiescent viral genomes. (ICP0) (Mus musculus) PubMed

 2124.

study provides evidence that ICP0 directly alters the chromatin structure of the HSV-1 genome during lytic infection [ICP0] (Mus musculus) PubMed

 2125.

an HSV-1 LAT(-) mutant that expresses cellular FLICE-like inhibitory protein under control of the LAT promoter and in place of LAT nucleotides 76 to 1667 had a reactivation phenotype similar to wild-type virus [FLIP and LAT genes] (Mus musculus) PubMed

 2126.

control of TBK1-mediated cell signaling by the gamma(1)34.5 protein contributes to herpes simplex virus infection[ gamma134.5 protein ] (Mus musculus) PubMed

 2127.

Using chemical inhibitors, the authors show that the ICP27-mediated activation of p38 signaling is responsible for the observed induction of apoptosis in the induced cell lines.[ICP27] (Mus musculus) PubMed

 2128.

The authors demonstrate that mitochondrial localization of UL12.5 relies largely on sequences located between UL12 residues 185 and 245 (UL12.5 residues 59 to 119).[UL12.5] (Mus musculus) PubMed

 2129.

Electron microscopic image reconstruction reveals that the ICP8 filaments are bipolar, with an asymmetric unit containing two subunits of ICP8 that constitute a symmetrical dimer. (Mus musculus) PubMed

 2130.

gamma 34.5 is involved in the impairment of innate immunity by inhibiting both type I interferon production and dendritic cell maturation. [gamma 34.5] (Mus musculus) PubMed

 2131.

Glycoprotein E is dispensable for retrograde axonal transport; however, it promotes HSV-1 spread from epithelial cells to neurites. [Glycoprotein E] (Mus musculus) PubMed

 2132.

arginine methylation of the ICP27 RGG box regulates its export activity (Mus musculus) PubMed

 2133.

LAT modulate latent infection in mouse trigeminal ganglia. [LAT] (Mus musculus) PubMed

 2134.

These results indicate that ICP27 RGG box methylation regulates interaction ALY and SRPK1 proteins. (Mus musculus) PubMed

 2135.

expression of two LAT sRNAs plays a role in the latency-reactivation cycle by inhibiting apoptosis and productive infection[LAT] (Mus musculus) PubMed

 2136.

Latency-associated transcript (LAT) exon 1 controls herpes simplex virus species-specific phenotypes (Mus musculus) PubMed

 2137.

The authors show that eIF2alpha dephosphorylation by gamma(1)34.5 is crucial for viral neuroinvasion.[gamma(1)34.5] (Mus musculus) PubMed

 2138.

results demonstrate that phosphorylation of HSV-2 VP22 at multiple serine residues is induced by UL13 and cellular kinase(s); distribution of VP22 is independent of its phosphorylation status but is controlled indirectly by UL13 kinase activity [VP22] (Mus musculus) PubMed

 2139.

ICP10 gene expression is sufficient to induce apoptosis in Jurkat cells, while its expression protects epithelial HEp-2 cells from apoptosis triggered by cycloheximide and tumor necrosis factor alpha.[ICP10] (Mus musculus) PubMed

 2140.

Interactions between the LR fusion protein and C/EBP-alpha promote the establishment of latency. [LR gene (ORF1&ORF2 fusion)] (Mus musculus) PubMed

 2141.

The authors demonstrated that an LR-encoded protein, open reading frame 2 (ORF-2), or ORF-2 fusion proteins encoded by alternatively spliced LR transcripts inhibit cold shock or Fas ligand-induced apoptosis in mouse neuroblastoma (neuro-2A) cells.[ORF-2] (Mus musculus) PubMed

 2142.

The study demonstrated that BICP27 is a nucleolar protein, adding BICP27 to the growing list of transactivators which localize to the nucleolus.[BICP27] (Mus musculus) PubMed

 2143.

required for efficient virus growth in vitro and the carboxy-terminal amino acids are not required for its function [glycoprotein K] (Mus musculus) PubMed

 2144.

Results support our hypothesis that the EICP27 protein participates in the trans-activation of EHV-1 promoters, and suggest its presence within RNA polymerase II preinitiation complexes that assemble at viral promoters.[EICP27, IE protein] (Mus musculus) PubMed

 2145.

Expression of full-length gp2 is sufficient to restore full respiratory virulence to the attenuated KyA strain. (gp2 protein) (Mus musculus) PubMed

 2146.

ETIF has an essential function in the replication cycle of EHV-1, and its main role appears to be in secondary envelopment [ETIF] (Mus musculus) PubMed

 2147.

IR2 downregulates EHV-1 gene expression by blocking immediate-early protein binding to viral promoters and/or squelching the limited supplies of transcription factors TFIIB and TATA box-binding protein. (IR2) (Mus musculus) PubMed

 2148.

description of the discovery of a second hybrid gene found in EHV-1 defective interfering particles but not in the standard virus; the new Hyb gene (Hyb2.0) contains 684 bp (5') of the IR4 ORF fused to 45 bp from the 3'portion of the UL5 gene[Hyb2.0] (Mus musculus) PubMed

 2149.

The possible role of the IR3 transcript in EHV-1 infection is discussed [IR3& IE] (Mus musculus) PubMed

 2150.

in contrast to the highly pathogenic parent virus, the IR4 deletion mutant failed to cause disease in the CBA mouse as judged by assessing body weight and clinical signs and was unable to replicate in the murine lung.[IR4] (Mus musculus) PubMed

 2151.

Transfection of cells with a plasmid expressing ORF63 but lacking the putative nuclear localization signal of the protein resulted in increased expression of the protein in the cytoplasm, ORF63 protein) (Mus musculus) PubMed

 2152.

IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity [IE63] (Mus musculus) PubMed

 2153.

IE63was able to downregulate the expression of reporter genes under the control of heterologous promoters, indicating that this viral factor can be involved in the VZV-mediated delayed host shutoff [IE63] (Mus musculus) PubMed

 2154.

results indicate that IE62 nuclear import is modulated as a result of direct phosphorylation of IE62 by ORF66 kinase [IE62, ORF66 kinase ] (Mus musculus) PubMed

 2155.

IE62 forms a complex with ORF9 protein in the cytoplasm at late times in infection. [IE62] (Mus musculus) PubMed

 2156.

findings show that the IE63 protein increases the release of CGRP from trigeminal neurons [IE63] (Mus musculus) PubMed

 2157.

IE63 affected transcription of a small number of cellular genes. It interfered with the TNF-inducibility of several NF-kappaB dependent genes by the accelerated resynthesis of the inhibitor IkappaBalpha. IE63. (Mus musculus) PubMed

 2158.

IE62 activation domain appears to selectively interact with a form of the Mediator complex lacking CDK8[ IE62 ] (Mus musculus) PubMed

 2159.

The transcriptional activation domain of IE62 directly with aa 402 to 590 of the MED25 subunit of the human mediator complex. (Mus musculus) PubMed

 2160.

CMV IE1 protein induces RelB NF-kappaB subunit via activation of JNK and AP-1 [CMV IE1 protein] (Mus musculus) PubMed

 2161.

results show that IE1(491aa) is composed of at least two domains that support replication, a region that complements ie1 mutant virus replication to low levels and an acidic domain that dramatically enhances complementation [IE1491aa] (Mus musculus) PubMed

 2162.

pp71 provokes slow reactivation of quiescent genomes, in conjunction with cell survival, represents a novel property for a viral structural protein [pp71] (Mus musculus) PubMed

 2163.

role vCXCL-1 plays during viral infection (Mus musculus) PubMed

 2164.

determined UL144 polymorphisms of HCMV strains from amniotic fluid of infected fetuses & compared them to strains from viremic adults; all five UL144 genotypes could be transmitted from mothers to fetuses & could cause congenital infection [UL144] (Mus musculus) PubMed

 2165.

Evasion of NK cell killing was mediated by human cytomegalovirus UL141 blocking surface expression of CD155 [UL141] (Mus musculus) PubMed

 2166.

UL142 is a novel HCMV-encoded MHC class I-related molecule (UL142) (Mus musculus) PubMed

 2167.

glycoprotein M/gN can elicit a virus-neutralizing antibody response in humans infected with human cytomegalovirus [glycoprotein N] (Mus musculus) PubMed

 2168.

UL80a amino-conserved domain involved in early steps of capsid assembly pathway. [UL80a] (Mus musculus) PubMed

 2169.

pp28 must accumulate in the assembly compartment for efficient envelopment of the particle; it has a role in the late stages of assembly, such as envelopment (Mus musculus) PubMed

 2170.

pUL50 AND pUL53 protein ate involved in the recruitment of protein kinase C, which is important for cytomegalovirus-induced distortion of the nuclear lamina.[pUL50 AND pUL53] (Mus musculus) PubMed

 2171.

These results suggest that pUL50 and pUL53 may play an important role in the exit of virions from the nucleus by inducing structural modifications of the nuclear lamina. {UL50, UL53] (Mus musculus) PubMed

 2172.

These results suggest that HCMV subverts innate immunity by suppressing type I IFN production of plasmacytoid dendritic cells during primary viral infection via its IL-10 homolog.[IL-10] (Mus musculus) PubMed

 2173.

results argue that the UL29/28 locus contributes to activation of immediate-early gene expression [UL28; UL29] (Mus musculus) PubMed

 2174.

may contribute to oncogenesis through its ability to promote cell survival by repressing TGF-beta signaling [K-bZIP] (Mus musculus) PubMed

 2175.

results reveal a particular feature of the transmembrane domain of tumor-derived CAO-LMP1 and suggest its possible contribution to the pathogenesis of nasopharyngeal carcinoma (Mus musculus) PubMed

 2176.

a tegument protein of the EBV homologous to VP16 of HSV1 and ORF22 of Varicella zoster virus. [BPLF1] (Mus musculus) PubMed

 2177.

regulation of LMP1 on the nuclear translocation of EGFR is critical for the process of nasopharyngeal carcinoma (Mus musculus) PubMed

 2178.

may directly engage signaling pathways to influence epithelial cell behavior such as cell adhesion and motility. [LMP2B] (Mus musculus) PubMed

 2179.

isolated and sequenced complete EBV LMP1 genes from 12 biopsy samples of salivary gland lymphoepithelial carcinoma (latent membrane protein 1) (Mus musculus) PubMed

 2180.

EBNA-LP strongly coactivated EBNA2 stimulation of LMP-1 and LMP2B RNAs, which are expressed from the viral divergent promoter. [LMP-1][LMP2B][EBNA-LP] (Mus musculus) PubMed

 2181.

Deletion of the entire EBNA-3B open reading frame from the EBV BAC had no adverse impact on growth of EBV-immortalized B cells, providing formal proof that EBNA-3B is not essential for EBV-mediated B-cell growth transformation in vitro. [EBNA-3B] (Mus musculus) PubMed

 2182.

LMP1-induced tyrosine phosphorylation of STAT1 is almost exclusively due to the NF-kappaB-dependent secretion of interferons in B cells.[LMP1] (Mus musculus) PubMed

 2183.

An association of the LMP1 cytoplasmic carboxyl terminus with caspase-8 by a heterodimerizing agent causes apoptosis. [LMP1--latent membrane protein 1] (Mus musculus) PubMed

 2184.

activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186 [BZLF1, BRLF1] (Mus musculus) PubMed

 2185.

diseases share a common signal pathway, through either the mutation or LMP1-mediated suppression of the SH2 domain protein 1A, Duncan's disease gene [LMP1] (Mus musculus) PubMed

 2186.

LMP1-mediated rodent fibroblast transformation is dependent upon activation of PI3K and Akt and is independent of activation of NF-kappaB [LMP1] (Mus musculus) PubMed

 2187.

gp350/220 is involved in Epstein-Barr virus invasion of host cells [gp350/220] (Mus musculus) PubMed

 2188.

EBNA-LP interacts with the promyelocytic leukemia nuclear body (PML NB)-associated protein Sp100 and displaces Sp100 and heterochromatin protein 1alpha (HP1alpha) from PML NBs. (Mus musculus) PubMed

 2189.

EB2 is essential for the nuclear export of most, but not all, late mRNAs produced from intronless genes. (EB2 protein) (Mus musculus) PubMed

 2190.

Real-time RT-PCR confirmed EBNA2-dependent expression of eight RNAs [Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2)] (Mus musculus) PubMed

 2191.

cloning, overexpression and purification of a C-terminal fragment of ZEBRA that encompasses the bZIP domain and its crystallization in complex with a DNA duplex[ZEBRA protein] (Mus musculus) PubMed

 2192.

EBNA3B co-localized with both EBNA3A & EBNA3C in nuclei of cells when overexpressed; identification of four potential nuclear-localization signals (NLSs); only two of the NLSs were found to be functional in the context of the full-length EBNA3B[EBNA3B] (Mus musculus) PubMed

 2193.

lyLMP-1 functions as a posttranslational negative regulator of LMP-1 oncogenesis.(lyLMP-1) (Mus musculus) PubMed

 2194.

The identification of 6 functional nuclear localization signals in the Epstein-Barr nuclear antigen 3A (EBNA3A) is reported. [EBNA3A] (Mus musculus) PubMed

 2195.

reveal distinct functional requirements for gH/gL and gp42 complexes in Epstein-Barr virus-mediated membrane fusion [gH and gL] (Mus musculus) PubMed

 2196.

antibodies to gp350/220 enhance infection of epithelial cells (Mus musculus) PubMed

 2197.

stronger DNA binding is required for ZEBRA to activate replication than that required to activate transcription[ZEBRA] (Mus musculus) PubMed

 2198.

The A157154C mutation in A73 gene might be correlated to the occurrence and development of nasopharyngeal carcinoma. (Mus musculus) PubMed

 2199.

In vitro methylation blocked binding of the cellular proteins c-Myc and ATF to the 5'-region of the EBER-1 gene, and silenced the expression of the EBER-1 and EBER-2 genes, transcribed by RNA polymerase III, in transfected cells.[EBER-1] (Mus musculus) PubMed

 2200.

Glycoprotein B is required for cell fusion in epithelial adn B cells. [gB] (Mus musculus) PubMed

 2201.

Growth-promoting properties of Epstein-Barr virus EBER-1 RNA correlate with ribosomal protein L22 binding [EBER1] (Mus musculus) PubMed

 2202.

These results indicate that herpesvirus saimiri utilizes the ORF 57 protein to recruit components of the exon junction complex and subsequently TAP to promote viral RNA export through the cellular mRNA export pathway. [ORF 57] (Mus musculus) PubMed

 2203.

data demonstrate that growth transformation by herpesvirus saimiri depends on a complex interaction of Tip with the T-cell tyrosine kinase Lck [Tip] (Mus musculus) PubMed

 2204.

Expression of the ORF57 protein induces nucleolar redistribution of human TREX (transcription/export) proteins that are involved in mRNA nuclear export. (ORF 57) (Mus musculus) PubMed

 2205.

Tip LBD1 binding did not cause gross structural changes in Lck SH3 but globally stabilized the domain and reduced the rate of partial unfolding by a factor of five. (Mus musculus) PubMed

 2206.

findings show that association between ORF73 and MeCP2 is essential for HVS chromosomal attachment and episomal persistence.[Orf73] (Mus musculus) PubMed

 2207.

viral oncoproteins saimiri transformation-associated protein of subgroup C induces NF-kappaB activation (Mus musculus) PubMed

 2208.

manipulation of the repeat revealed that the motif EEAEEAEEE was sufficient to cause a reduction in recognition of ORF73 by CD8(+) cytotoxic T lymphocytes. (Mus musculus) PubMed

 2209.

the membrane-proximal amphipathic helix preceding Tip's transmembrane domain mediates lipid raft localization and membrane deformation [tyrosine kinase interacting protein, TIP] (Mus musculus) PubMed

 2210.

These data suggest that the GAAGRG motif may be required within a HVS intronless mRNA for recognition by the ORF57 protein. [ORF57 protein] (Mus musculus) PubMed

 2211.

The authors demonstrate that ORF57 recruits several members of hTREX, namely Aly, UAP56 and hTHO-complex proteins, onto the viral mRNAs to assemble an export-competent ribonucleoprotein particle. (Mus musculus) PubMed

 2212.

activation of p38 MAPK and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and TNFR1/TNFa expression [pX, hepatitis B virus] (Mus musculus) PubMed

 2213.

hepatitis B virus M protein has an autoregulatory function on surface gene expression [M protein] (Mus musculus) PubMed

 2214.

determination of minimal distance between the matrix and transmembrane domains of the large hepatitis B virus envelope protein [envelope protein L] (Mus musculus) PubMed

 2215.

The HBxAg is associated with decreased expression of E-cadherin, accumulation of beta-catenin in the cytoplasm and nucleus, and increased cell migration, which may contribute importantly to hepatocarcinogenesis.[HBxAg] (Mus musculus) PubMed

 2216.

mRNA differential display analysis of the role of hepatitis B virus HBx and MHBs in hepatocellular carcinoma [MHBs] (Mus musculus) PubMed

 2217.

Efficiently cleaves target mRNA at specific sites in vitro (10-23 DNA enzyme) (Mus musculus) PubMed

 2218.

Hepatitis B e antigen (HBeAg) status can be used with caution in selected recipients without significantly affecting graft and patient outcome.(HbeAg) (Mus musculus) PubMed

 2219.

A higher prevalence of pre-S deletion was found in carriers with progressive liver diseases compared with HBV chronic carriers. (pre-S1 protein, pre-S2 protein, HBV) (Mus musculus) PubMed

 2220.

protein kinase A facilitates hepatitis B virus(HBV) core assembly through phosphorylation of the HBV capsid proteins at Ser87 [Capsid Proteins] (Mus musculus) PubMed

 2221.

HBx mutant that did not interact with cyclin E/A failed to destabilize p27(Kip1) or deregulate the cell cycle. (HBx protein) (Mus musculus) PubMed

 2222.

findings demonstrate that the C-terminal region of pre-S1 and a putative translocation motif in pre-S2 are not necessary for HDV infectivity and, by inference, are not needed for HBV attachment and entry into susceptible cells [L protein] (Mus musculus) PubMed

 2223.

the presence of precore/core promoter mutations was associated with fulminant hepatitis, severe coagulopathy and mortality [HBeAg; Hepatitis B envelope antigen] (Mus musculus) PubMed

 2224.

The post-translational modification of the large L envelope protein by N-glycosylation is reported.[L protein] (Mus musculus) PubMed

 2225.

These results establish that unlike HBx, MHBs(t) enhances TRAIL-induced hepatocyte apoptosis through a novel mechanism that involves ERK2. (Mus musculus) PubMed

 2226.

A new mutation pattern in HBV reverse transcriptase, A181S+M2041, arising under lamivudine treatment confers cross-resistance to adefovir dipivoxil both in vivo and in vitro. (Mus musculus) PubMed

 2227.

HBx deletion, especially the COOH-terminal deletion of HBx is a frequent event in HBV-associated HCC tissues in China. Deletion and probably integrated forms of the HBx gene may be implicated in liver carcinogenesis [HBx]. (Mus musculus) PubMed

 2228.

Results indicate that HBSP interacts with Bcl-2/Bcl-xl in vitro and induces apoptosis in HepG2 cells [HBSP]. (Mus musculus) PubMed

 2229.

Both replication and gene expression of HBV require functional CREB and HBV-CRE. CRE decoy oligonucleotides and overexpression of CREB mutants can effectively block HBV life cycle. Interventions against CREB could be new way to treat HBV infection. (Mus musculus) PubMed

 2230.

The structural properties of dimeric HBc, as well as its dynamics and intermolecular interactions were characterised, at atomic resolution.[Hbc] (Mus musculus) PubMed

 2231.

The study reveals genotypic differences in HBeAg processing and implicates furin as the major enzyme involved in the cleavage of the first and second RXXR motifs. (Mus musculus) PubMed

 2232.

These results demonstrate that group II NPV F proteins can be functionally replaced with a homologue of other group II NPVs, suggesting that the interaction of F with other viral or host proteins is not absolutely species-specific. [F protein] (Mus musculus) PubMed

 2233.

molecular analysis of Helicoverpa zea CYP6B8 and CYP321A1 [CYP6B8, CYP321A1] (Mus musculus) PubMed

 2234.

DNA polymerase X binds the ssDNA without detectable cooperativity and with very modest base specificity[DNA polymerase X ] (Mus musculus) PubMed

 2235.

Results discuss interactions of the DNA polymerase X of African swine fever virus with double-stranded DNA, and describe the functional structure of the complex [DNA polymerase X]. (Mus musculus) PubMed

 2236.

the specific structure necessary to recognize the short gaps is induced by magnesium binding to the enzyme. In the absence of Mg+2, pol X looses its selectivity for short ssDNA gaps.[DNA polymerase X] (Mus musculus) PubMed

 2237.

Heterogeneous nuclear ribonucleoprotein K was identified as interacting cellular protein with the abundant immediate early protein p30 from African swine fever virus in a macrophage cDNA library screening. (p30) (Mus musculus) PubMed

 2238.

These results agree well with kinetic data for pol X and provide a structural/dynamic basis to explain, at atomic level, the fidelity of this polymerase compared with other members of the X family.[DNA polymerase X] (Mus musculus) PubMed

 2239.

DNA polymerase x fidelity is altered by the redox state of the enzyme and its related conformational changes[DNA POLYMERASE X] (Mus musculus) PubMed

 2240.

The authors show that recombinant ASFV g5Rp hydrolyzes the mRNA cap when tethered to an RNA moiety, liberating m(7)GDP as a product.[g5Rp] (Mus musculus) PubMed

 2241.

E5 from both BPV-1 and BPV-4 disturbs the actin cytoskeleton and focal adhesions in transformed bovine cells [E5] (Mus musculus) PubMed

 2242.

E5 is a player in the transformation of equine cells and the induction of sarcoids, and a potential major cause of MHC I downregulation and hence poor immune clearance of tumour cells. [E5] (Mus musculus) PubMed

 2243.

NEW ENTRY human papillomavirus E7 oncoprotein The E7 chaperone can stably bind model polypeptides and hold them in a state with significant tertiary structure, but does not bind the fully native proteins (Mus musculus) PubMed

 2244.

Binding of E2 at the binding sites play an important role in overcoming inhibition of E1 complex formation caused by the binding of CDP to the origin of replication. (E2 protein, papillomavirus) (Mus musculus) PubMed

 2245.

E6*I mRNAs of high-risk high-risk human papillomaviruses are responsible for E7 production [E7 oncoprotein] (Mus musculus) PubMed

 2246.

evasion of apoptosis mediated by HPV-16 E6 and E7 is associated with increased Bcl-2 and decreased Bak in laryngeal carcinogenesis and the decreased level of Bak by E6 and E7 is caused by reducing its protein stability.[E6, E7] (Mus musculus) PubMed

 2247.

We report here that the HPV1 E4 protein, in the presence of a soluble form of the replication-licensing factor (RLF) Cdc6, inhibits initiation of cellular DNA replication in a mammalian cell-free DNA replication system. [E4] (Mus musculus) PubMed

 2248.

it is shown here for the first time that the HPV-18 and -45 E7 proteins can be detected in cervical carcinoma biopsies [E7] (Mus musculus) PubMed

 2249.

these data suggest that HPV-45 E7 is a transforming protein and that abrogation of cell cycle control contributes to its oncogenic potential.[E7] (Mus musculus) PubMed

 2250.

a fraction of P6 immunoprecipitates with DRB4 in CaMV-infected cells. (P6) (Mus musculus) PubMed

 2251.

Three-dimensional structure of the R115E mutant 2'-deoxycytidylate deaminase suggests a hypothesis for activity of the mutant as a dimer, and a model for the mechanism for allosteric regulation of the wild-type enzyme. [2'-deoxycytidylate deaminase] (Mus musculus) PubMed

 2252.

RNA ligase type 1 from bacteriophage T4 (Rnl1) is involved in countering a host defense mechanism by repairing 5'-PO4 and 3'-OH groups in tRNA(Lys). (T4 RNA ligase) (Mus musculus) PubMed

 2253.

contribution of both MuA and DNA supercoiling to the 5-noded Mu synapse built at the 3-way junction [transposase MuA] (Mus musculus) PubMed

 2254.

gp44 is an essential protein for baseplate assembly & forms a trimer comprising a complex consisting of 42 kDa & 40 kDa subunits that had been cleaved in C-terminal region. Thermodynamic analysis shows that C-terminal region forms a flexible domain[gp44] (Mus musculus) PubMed

 2255.

Data show that gp44 exists as a trimer exhibiting a hub-like structure with an inner diameter of 25 angstroms through which DNA can presumably pass during infection [gp44]. (Mus musculus) PubMed

 2256.

Bacteriophage Mu baseplate protein gene product 44 (gp44) crystsals diffract X-rays to at least 2.1 A resolution and are stable in the X-ray beam and are therefore appropriate for structure determination (gp44) (Mus musculus) PubMed

 2257.

MuA assembles DNA hairpin substrates into a catalytically competent transpososome, open the hairpin ends and accurately join the opened ends to the target DNA (MuA). (Mus musculus) PubMed

 2258.

A subset of the six subunits of MuA associated with their cognate sub-sites at L and R communicate with the enhancer to trigger the stepwise assembly of the functional transpososome (Mus musculus) PubMed

 2259.

data prove the saccharidic nature of the bacterial receptor recognized by phage p2 and identify the position of its binding site in the RBP (receptor binding protein) head domain [RBP] (Mus musculus) PubMed

 2260.

Crystal structure of a truncated version of protein gpD [gpD] (Mus musculus) PubMed

 2261.

beta protein can catalyze steps that are central to both strand annealing and strand invasion pathways of recombination(beta protein) (Mus musculus) PubMed

 2262.

NMR solution structure of the monomeric form of the bacteriophage lambda capsid stabilizing protein gpD [capsid protein gpD] (Mus musculus) PubMed

 2263.

the N/boxB complex exists in a dynamical two-state equilibrium between stacked and unstacked conformations; the present work determines the nature of interactions responsible for this sequence-dependent behavior (Mus musculus) PubMed

 2264.

provide direct experimental support for the long presumed cooperative assembly of gpNu1 and IHF at the cos sequence of lambda DNA [gpNu1] (Mus musculus) PubMed

 2265.

Characterization of a previously unrecognized phosphodiesterase activity of lambda phosphatase (lambda phosphatase). (Mus musculus) PubMed

 2266.

The X-ray structure of the bacteriophage SPP1 portal protein in its isolated 13-subunit form and the pseudoatomic structure of a 12-subunit assembly, is described.[Portal protein] (Mus musculus) PubMed

 2267.

Results suggest that NusAE136K suppresses Nun-arrest when it is a component of the transcription elongation complex, perhaps, in part, by blocking interactions between the Nun C terminus and RNA polymerase and DNA. (Mus musculus) PubMed

 2268.

We propose that RNase III processing site enhances the on-rate of Nun at nutL of lambda phage, stimulating Nun-mediated arrest in vitro.[Nun] (Mus musculus) PubMed

 2269.

Coliphage HK022 Nun protein targets phage lambda nut boxB RNA and acts as a transcriptional terminator, counteracting the phage lambda N protein, a suppressor of transcription termination. [Nun protein] (Mus musculus) PubMed

 2270.

gp26 is very likely a triple stranded coiled-coil protein [gp26] (Mus musculus) PubMed

 2271.

Gp26 is phage P22-encoded tail accessory factor essential for stabilization of viral DNA in capsid. In solution, gp26 exists as extended triple-stranded coiled-coil protein sharing profound similarities with class I viral membrane-fusion protein[gp26] (Mus musculus) PubMed

 2272.

In the P22 tail needle, the authors identified an 85-residue-long helical domain, termed MiCRU (minimal coiled-coil repeat unit), that can be inserted in-frame inside the gp26 helical core, preserving the straight morphology of the fiber. (Mus musculus) PubMed

 2273.

The phi29 DNA polymerase thumb subdomain may be responsible for the coordination of polymerization and exonuclease activities (DNA polymerase). (Mus musculus) PubMed

 2274.

The X-ray crystal structures of phi29 DNAP, a member of the protein-primed subgroup of the B-family of polymerases, complexed with primer-template DNA. [DNA polymerase] (Mus musculus) PubMed

 2275.

Results revealed that protein p56 blocked the DNA-binding site of uracil-DNA glycosylase (UDG). Thus, protein p56 could mimic DNA structural features in order to inhibit UDG (p56). (Mus musculus) PubMed

 2276.

protein p56 ensures an efficient viral DNA replication, preventing the deleterious effect caused by uracil-DNA glycosylase (UDG) when it eliminates uracil residues present in the phi29 genome[p56] (Mus musculus) PubMed

 2277.

The helicase rate of stimulation depends upon the DNA synthesis rate and does not rely on specific interactions between T7 DNA polymerase and the carboxy-terminal residues of T7 helicase [T7 helicase gp4] (Mus musculus) PubMed

 2278.

T7 RNA polymerase pausing signal within this critical DNA structure could interfere with normal regulation of RNA transcription. (RNA polymerase) (Mus musculus) PubMed

 2279.

Ser substitution at position 102 affects the structural stability of thioredoxin resulting in a reduced binding affinity for gp5 and loss of processivity [gp5] (Mus musculus) PubMed

 2280.

During bacteriophage T7 infection, the Escherichia coli RNA polymerase beta' subunit is phosphorylated by the phage-encoded kinase Gp0.7 (Mus musculus) PubMed

 2281.

data show that the form of the complex between endonuclease I and a DNA junction depends on the core of the junction and on interactions with the first six base-pairs of the arms containing the 5' ends of the continuous strands [endonuclease I] (Mus musculus) PubMed

 2282.

quaternary protein structure of gene 4 primase/helicase [gene 4] (Mus musculus) PubMed

 2283.

Night-time restricted feeding altered oscillation of the peripheral clock and mPai-1 mRNA rhythm (PAI-1) (Mus musculus) PubMed

 2284.

Required in mediating Notch signaling in the developing cardi(ac and vascular systems. (Hesr2) (Mus musculus) PubMed

 2285.

NS2 required for efficient viral infection, but dispensable for SAAB (Smn-associated APAR (autonomous parvovirus-associated replication) bodies ) formation. [NS2] (Mus musculus) PubMed

 2286.

NS2 was expressed at high ratios even in the absence of upstream mutations, and progeny accumulation was efficient. (ns2 protein) (Mus musculus) PubMed

 2287.

findings suggest that the accumulated level of NS2 may play a larger role in the host ranges of the fibrotropic strain and the lymphotropic strain of minute virus of mice than previously appreciated [NS2] (Mus musculus) PubMed

 2288.

the NS2P isoform, even when expressed at a level lower than that of NS2Y, performs a critical role in infection of A9 cells that cannot be accomplished by the NS2Y isoform alone [NS2] (Mus musculus) PubMed

 2289.

LIF, cAMP signaling cascades,Myt1 play roles in the differentiation of oligodendrocytes through their action on the Opalin oligodendrocyte enhancer. (Mus musculus) PubMed

 2290.

Silencing Cep120 in the developing neocortex impairs both interkinetic nuclear migration (INM), a characteristic pattern of nuclear movement in neural progenitors, and neural progenitor self-renewal. (Mus musculus) PubMed

 2291.

A supraphysiological nuclear export signal in an endogenous protein, the NS2 protein of parvovirus Minute Virus of Mice (MVM), is identified.[NS2] (Mus musculus) PubMed

 2292.

Blocking expression of the proline-rich 11-kDa protein significantly reduced B19 viral infectivity and expression of the 11-kDa protein was critical for VP2 capsid production and trafficking in infected cells. (11-kilodalton protein, human parvovirus B19) (Mus musculus) PubMed

 2293.

we have identified a novel cellular AAV-2 Rep78/Rep68 interaction partner, KCTD5, located predominantly in the cytoplasm.[Rep78] (Mus musculus) PubMed

 2294.

Mre11 repair complex (MRN) poses a barrier to AAV and that the helper function provided by E1b55K/E4orf6 involves MRN degradation.[E1b, E4] (Mus musculus) PubMed

 2295.

Beet curly top virus (BCTV) C4 interacted with two members of the shaggy-related protein kinase family (AtSKeta and AtSKzeta) and a putative leucine-rich repeat receptor-like kinase (LRR-RLK) in a yeast two-hybrid assay.[C4 protein] (Mus musculus) PubMed

 2296.

The cloned cDNA is rice black-streaked dwarf virus S7. [S7] (Mus musculus) PubMed

 2297.

The cloned S9-1 gene contains 1900 base pairs and encoded a 40 kD protien. [S9-1] (Mus musculus) PubMed

 2298.

these results suggest that P9-1 is required for viroplasm formation and that it plays an important role in the early stages of the virus life cycle by forming intracellular viroplasms that serve as the sites of virus replication and assembly.[P9-1] (Mus musculus) PubMed

 2299.

chracterization of Pns4; it associated with large cytoplasmic fibrils and formed novel minitubules in infected cultured cells of its leafhopper insect vector; might be involved in the process of assembly of the RDV virion [Pns4] (Mus musculus) PubMed

 2300.

Rice dwarf virus exploits tubules composed of a nonstructural viral protein (Pns10) and actin-based filopodia to move into neighboring cells.[Pns10] (Mus musculus) PubMed

 2301.

P2 shares structural features with membrane-fusogenic proteins encoded by enveloped animal viruses.(capsid protein P2) (Mus musculus) PubMed

 2302.

VP1 protein of IBDV is involved in the efficiency of viral replication and modulates the virulence in vivo. (VP1 protein) (Mus musculus) PubMed

 2303.

The IBDV capsid protein contains a functional alpha 4 beta 1 integrin ligand motif, and a single point mutation on this triplet abolishes the cell-binding activity of IBDV. [capsid protein] (Mus musculus) PubMed

 2304.

crystallization and preliminary diffraction analysis of various mutant IPNV VP4 constructs [VP4 protease] (Mus musculus) PubMed

 2305.

the crystal structure of VP4 protease from infectious pancreatic necrosis virus shows that it has an acyl-enzyme complex for an intermolecular self-cleavage reaction [VP4] (Mus musculus) PubMed

 2306.

An IPNV infection of susceptible and permissive CHSE-214 cells could only be neutralized by IgG preparations obtained from rabbits immunized with authentic VP2. (Mus musculus) PubMed

 2307.

These results suggest the essential role of Tim40 in sorting/assembly of small Tim proteins [Tim40]. (Mus musculus) PubMed

 2308.

Replication protein A stimulated the ATPase activity of the Mcm467 complex. (Mcm467) (Mus musculus) PubMed

 2309.

Requirements for the binding of Sindbis virus capsid protein to the cytoplasmic domain of the E2 glycoprotein, (capsid) (Mus musculus) PubMed

 2310.

investigated the role of the amino acid residues located at or around position E2 391 and constraints on the length of the endodomain on virus assembly [E2 protein] (Mus musculus) PubMed

 2311.

Seven sites of biotin modification were identified in the E2 glycoprotein, while one site of modification in the E1 glycoprotein (K16) was identified, confirming that the E1 protein is almost completely buried in the virus structure.[E2] (Mus musculus) PubMed

 2312.

Deletions in the glycoprotein E2 endodomain (delta406-407, delta409-411, and delta414-417) resulted in the failure to assemble virions in mammalian cells [glycoprotein E2] (Mus musculus) PubMed

 2313.

SIN nsP2 is critically involved in cytopathic effect development, determined by the integrity of the carboxy-terminal peptide of this protein located outside its helicase and protease domains(nonstructural protein nsP2) (Mus musculus) PubMed

 2314.

The defective and lethal mutants give insight into regions of E2 important for protein stability, transport to the cell membrane, E1-E2 contacts, and receptor binding [E2] (Mus musculus) PubMed

 2315.

analysis of free cysteinyl residues in the Sindbis virus E1 and E2 glycoproteins [E1, E2] (Mus musculus) PubMed

 2316.

Data suggest that Sindbis virus infection leads to the formation of two types of nsP3-containing complexes, one of which is found in association with the plasma membrane and endosome-like vesicles, while the second is coisolated with cell nuclei [nsP3]. (Mus musculus) PubMed

 2317.

These results establish the bidirectional transport of nsP2 across the nuclear membrane, suggesting that a critical function of nsP2 during infection involves its shuttling between the cytoplasm and the nucleus.(nsP2) (Mus musculus) PubMed

 2318.

results demonstrated a requirement for residues located between amino acids 994-1102 of the RV P200 polyprotein, besides its cleavage site for RV protease trans-activity [P200] (Mus musculus) PubMed

 2319.

Two disulfide bonds in the membrane-adjacent part of the E1 ectodomain are sufficient to generate conformations with a high and specific antigenicity[ E1 envelope protein ] (Mus musculus) PubMed

 2320.

The effect of nsp3 mutations on replicase polyprotein processing was investigated, and several mutations were found to influence processing of the region downstream of nsp3 by the nsp4 main protease; none of the nsp3 mutations was tolerated.[nsp3] (Mus musculus) PubMed

 2321.

E protein - position 123 in the E protein is responsible for determining the growth properties and pathogenicity of JEV (Mus musculus) PubMed

 2322.

NMR assignments for domain III of the West Nile virus envelope protein [env] (Mus musculus) PubMed

 2323.

there is a critical residue in the C protein of West Nile virus that potentially plays a role in stabilizing the homotypic interaction (Mus musculus) PubMed

 2324.

NS1 protein is a viable early diagnostic marker of west nile virus infection. (NS1 protein) (Mus musculus) PubMed

 2325.

findings suggest that West Nile virus capsid protein could function as a negative regulator of Hsp70 chaperone activities by binding to the substrate binding domain of Hsp70 [capsid protein] (Mus musculus) PubMed

 2326.

identified important enzyme-substrate interactions that define substrate specificity for NS3 protease [NS3 protease] (Mus musculus) PubMed

 2327.

extracellular NS1 may function to minimize Soluble and cell-surface-associated nonstructural protein 1 binds to and recruits the complement regulatory protein factor H (Mus musculus) PubMed

 2328.

three-dimensional structure (at 3.1 A resolution) of the NS3 helicase domain (residues 186-619; NS3:186-619) from Kunjin virus, an Australian variant of the West Nile virus (Mus musculus) PubMed

 2329.

An effective and highly specific interaction of the surface glycoprotein E domain II (DII) of the tick born encephalitis and Dengue viruses with the laminin binding protein (LBP), is shown.[Glycoprotein E] (Mus musculus) PubMed

 2330.

tick-borne encephalitis virus -NS5 has high affinity to regulating synaptic membrane exocytosis-2 (RIMS2) and Scribble, whereas DENV-NS5 binds primarily to the tight junction protein zonula occludens-1 (ZO-1) [ns5] (Mus musculus) PubMed

 2331.

In the partially surface-exposed BC loop of the envelope protein methionine-304 and valine-324 were identified as being critical for the structure of the loop.[envelope protein] (Mus musculus) PubMed

 2332.

The crystal structure of RdRp containing an Asn438 duplication shows that the "N-terminal domain," which occurs only in pestiviruses such as BVDV, interacts with the polymerase component of the same polypeptide chain. (RdRp) (Mus musculus) PubMed

 2333.

The viral envelope glycoprotein E(rns) inhibits IFN expression induced by extracellular viral ssRNA and dsRNA. [E(rns)] (Mus musculus) PubMed

 2334.

De novo initiation pocket mutations have multiple effects on hepatitis C virus RNA-dependent RNA polymerase activities. (Mus musculus) PubMed

 2335.

Mutations in the HCV core gene that would encode a truncated core protein were found in 4 of the 8 hepatocellular carcinoma patients (Mus musculus) PubMed

 2336.

Amino acid alterations in HVR1 protein, ISDR and core antigen of hepatitis C virus associated with serum alanine aminotransferase increases. (Mus musculus) PubMed

 2337.

HCV core protein (HCV-C)is involved in a tight modulation of HCV translation initiation, depending on its concentration, which suggests an important biological role of this protein in viral gene expression. (HCV core protein; HCV-C) (Mus musculus) PubMed

 2338.

HCcAg (core protein) was detected in the nucleii of nonparenchymal liver cells from chronically HCV-infected patients [core protein] (Mus musculus) PubMed

 2339.

NS5A-mediated phosphaatidylinositol 3-kinsae activation is a contributory factor in the increasingly common association between HCV infection and the development of hepatocellular carcinoma. (NS5A) (Mus musculus) PubMed

 2340.

biological effects of Hepatitis C virus (HCV) core protein on cell cycle could be an additional viral mechanism for both HCV resistance to interferon (IFN) and hepatocarcinoma HCV-related pathogenesis [Hepatitis C virus core protein] (Mus musculus) PubMed

 2341.

C-terminal 18 amino acids of HCV core were crucial for core secretion. HCV may utilize a unique core release mechanism to escape immune surveillance, thereby potentially representing feature of HCV morphogenesis. (HCV core protein) (Mus musculus) PubMed

 2342.

A hepatitis C virus protein; study of its conformation and zinc binding domain.(NSrA protein) (Mus musculus) PubMed

 2343.

results suggest that interaction of core protein with mitochondria and subsequent oxidation of the glutathione pool and complex I inhibition may be an important cause of the oxidative stress seen in chronic hepatitis C [core protein] (Mus musculus) PubMed

 2344.

These biochemical and functional analyses identified a number of residues in the HCV RNA-dependent RNA polymerase(RdRp) that are important for HCV RNA synthesis.[RdRp] (Mus musculus) PubMed

 2345.

identification of interaction between HBcAg and the novel protein C12 (Mus musculus) PubMed

 2346.

the target of NS3/4A is the mitochondrial antiviral signaling protein, MAVS, that activates NF-kappaB and IFN regulatory factor 3 to induce type-I interferons [NS3 and NS4A] (Mus musculus) PubMed

 2347.

specific amino acid substitutions in hepatitis C virus NS3 impair p53 interaction and anti-apoptotic activity of NS3 (Mus musculus) PubMed

 2348.

The cleaveage of nonstructural protein 5A(NS5A) of the hepacivirus at two sites, and its targeting to different caspases are reported.[NS5A] (Mus musculus) PubMed

 2349.

data suggested that the introduction of HCV core protein results in an increase in expression of IL-6, gp130, leptin receptor, and Stat3 in human hepatocytes [core protein] (Mus musculus) PubMed

 2350.

Results indicate that hepatitis C virus NS5A protein may be directly involved in the induction of chromosome instability via mitotic cell cycle dysregulation [NS5A]. (Mus musculus) PubMed

 2351.

identification of several clusters of genes that are differentially expressed in human B lymphocytes expressing HCV core, suggesting a potential impairment of antigen processing and presentation (Mus musculus) PubMed

 2352.

crystal structure of the catalytic domain of the NS2-3 protease at 2.3 A resolution [NS2-3 protease] (Mus musculus) PubMed

 2353.

Core protein, detectable in the plasma of HCV infected patients, triggers plasmacytoid dendritic cell (PDC) defects that are likely to contribute to HCV viral escape from immune responses. (N protein; nucleocapsid) (Mus musculus) PubMed

 2354.

Transient or stable NS5A expression inhibits STAT1 phosphorylation in a dose-dependent manner in hepatocyte-derived cell lines. The NS5A may interact with STAT1, specifically, the N-terminal 488 amino acids of STAT1. STAT1 protein, hepatitis C (Mus musculus) PubMed

 2355.

interferon-inducible gene 27 (IFI27) was highly expressed in NS3 and NS5A-infected hepatocytes and HCV-related CLD or HCC (NS3, NS5) (Mus musculus) PubMed

 2356.

sequence barriers in RNA modulate NS3 activity, whichdepends on barriers ahead of the opening fork of the RNA [NS3 helicase] (Mus musculus) PubMed

 2357.

Variants of full-length hepacvirus NS3 constitute effective models for resistance profiling of NS3 protease inhibitors. (Mus musculus) PubMed

 2358.

Ribovarin induces mutations in HVC NS5A sequence, modifying infectivity and interferon sensitivity. (Mus musculus) PubMed

 2359.

These data suggest that HCV core protein may contribute to hepatocellular injury by increasing both steady-state levels of prooxidants and the susceptibility of hepatocytes to damage by impairing their response to other sources of oxidative stress.[HO-1] (Mus musculus) PubMed

 2360.

Synthetic siRNA against NS5BHCV inhibited HCV replication and viral proteins levels and thereby becomes a powerful strategy to combat hepatitis C virus [NS5BHCV]. (Mus musculus) PubMed

 2361.

Hepatitis C virus non-structural 5A protein (NS5A) has central role in viral life cycle and in the progression of liver disease. (Mus musculus) PubMed

 2362.

Nonstructural protein 5A proteinof hepatitis C virus plays an important role in the regulation of viral replication, interferon resistance, and apoptosis. [Nonstructural protein 5A] (Mus musculus) PubMed

 2363.

Engagement of gC1qR on DCs by HCV core limits the induction of Th1 responses and may contribute to viral persistence.[Core protein] (Mus musculus) PubMed

 2364.

Response of HCV-1b infected patients towards interferon therapy is influenced by the mutations within the interferon sensitivity determining region of NS5A gene. (Mus musculus) PubMed

 2365.

Designed protease inhibitors based on structural features of hepatitis C virus NS3 protease. (Mus musculus) PubMed

 2366.

NS5ATP9 is a non-structural protein 5A (NS5A) up-regulation gene which may play a role in the pathogenesis of HCV-associated hepatocellular carcinoma. (Mus musculus) PubMed

 2367.

Aim of the studies included detection and subcellular localization of three HCV proteins (NS3, NS5A and C) in liver biopsies from adults (n=19) with chronic, long lasting hepatitis C as related to hepatocyte proliferative activity.[NS3, NS5A, C] (Mus musculus) PubMed

 2368.

support interactions that include a 1:1 complex formed between NS3 and NS5B[NS3 helicase and NS5B] (Mus musculus) PubMed

 2369.

data suggest an important role for mitochondria in the modulation HCV NS4A-induced inhibition of HCV core-mediated cell growth [NS4A protein] (Mus musculus) PubMed

 2370.

Mutations in NS5A causing an assembly defect in hepatitis C virus can be rescued by trans-complementation. (Mus musculus) PubMed

 2371.

Collectively, these results provide the first evidence for a genetic interaction between NS4B and NS3 important for productive HCV RNA replication.[NS3, NS4B] (Mus musculus) PubMed

 2372.

large kinetic step size of NS3 unwinding reflects a delayed, periodic release of the separated RNA product strand from a secondary binding site that is located in the NTPase domain (Domain II) of NS3[ NS3 helicase] (Mus musculus) PubMed

 2373.

The structure of the inhibitor/NS3p complex is very similar to that of the NS3p-NS4A complex, showing that binding of the NS4A cofactor is not the only event leading to a stable active-site conformation.[NS3, NS4A] (Mus musculus) PubMed

 2374.

The protease domain with the NS4A peptide, in a covalent or noncovalent complex, is a good model for the protease activity of native full-length nonstructural proteins NS3-NS4A. (Mus musculus) PubMed

 2375.

In conclusion, the core gene contains an internal signal that stimulates the initiation of protein synthesis at or near codon 91, leading to the production of p8.[p8] (Mus musculus) PubMed

 2376.

monomer-monomer interface of NS5A(33-202) features an extensive buried surface area involving the most-highly conserved face of each monomer[ NS5A ] (Mus musculus) PubMed

 2377.

impairment of Hsp60 function through binding of HCV core protein contributes to HCV viral pathogenesis by ROS generation and amplification of the apoptotic effect of TNF-alpha.(HVC core protein) (Mus musculus) PubMed

 2378.

The authors propose that although domain III of NS5A is dispensable for RNA replication, it nevertheless influences this process. (Mus musculus) PubMed

 2379.

NS5A and core proteins induce oxidative stress-mediated Ca(2+) homeostasis alterations in human hepatocyte-derived cells, which might underlie the effects of both proteins in the pathogenesis of liver disorders associated to HCV infection [NS5A]. (Mus musculus) PubMed

 2380.

Formation of N-terminally truncated NS5A fragments could represent a mechanism to regulate HCV replication by withdrawal of essential factors from the replicon complex [NS5A]. (Mus musculus) PubMed

 2381.

HCV NS3protein inhibits the interferon transmission system, and suppresses activation of the interferon-stimulated response element. (Mus musculus) PubMed

 2382.

The three-dimensional structure of the HCV polymerase from genotype 2b was determined to 1.9-A resolution and compared with the genotype 1b enzyme.[NS5B] (Mus musculus) PubMed

 2383.

Luciferase assay showed that hepatitis C virus NS4B also activates the multifunctional transcription factor, NF-kappaB, in a dose-dependent manner through Ca(2+) signaling and reactive oxygen species.[NS4B] (Mus musculus) PubMed

 2384.

Nonstructural HCV viral protein NS5A is sufficient to activate a calpain cysteine protease, leading to degradation of Bid [NS5a]. (Mus musculus) PubMed

 2385.

hepatitis c virus RNA-dependent RNA polymerase -- structural and functional analysis in HCV strain JFH1 (Mus musculus) PubMed

 2386.

C-terminal leucine is locked in the active site, and mutation or deletion of this residue could therefore alter the conformation of NS2 and disrupt potential protein-protein interactions important for infectious particle production. (NS2 PROTEIN) (Mus musculus) PubMed

 2387.

analysis of nonstructural proteins 8 and 9 of human coronavirus 229E [nsp8, nsp9] (Mus musculus) PubMed

 2388.

analysis of SARS coronavirus main proteinase (Mpro) [3C or Mpro] (Mus musculus) PubMed

 2389.

The highly conserved amino acid sequence of the ORF4 protein among clinical isolates suggests that the protein plays an important role in vivo. [ORF4] (Mus musculus) PubMed

 2390.

Within the tightly controlled interplay of the two protease activities, PL2pro plays a universal and essential proteolytic role that appears to be assisted by the PL1pro paralog at specific sites.[PL1pro, PL2pro] (Mus musculus) PubMed

 2391.

Both forms of the Nsp9 dimer are biologically relevant; the occurrence of the disulfide-bonded form may be correlated with oxidative stress induced in the host cell by the viral infection.[Nsp9] (Mus musculus) PubMed

 2392.

crystal structure of spike protein[spike protein] (Mus musculus) PubMed

 2393.

nsp2 proteins of mouse hepatitis virus and SARS coronavirus are not critical for viral replication [nsp2] (Mus musculus) PubMed

 2394.

TGEV spiker protein belongs to the class I fusion protein, characterized by the existence of two heptad-repeat (HR) regions, HR1 and HR2 [spiker] (Mus musculus) PubMed

 2395.

These results indicate that SeV V protein counteracts IRF-3-mediated innate antiviral immunity for efficient virus replication and pathogenesis in mice [V protein] (Mus musculus) PubMed

 2396.

From our data, we conclude that de novo synthesis of SeV N and P proteins is a key step for viral gene expression that facilitates the transition from preliminary to normal primary transcriptional activity. [N protein] (Mus musculus) PubMed

 2397.

PD protein localized in nuclear and cytoplasmic compartments of HPIV 3 infected cells.[PD protein] (Mus musculus) PubMed

 2398.

when P protein was co-expressed with the L protein, the former bound to a domain spanning the N-terminal 1060 amino acids of the latter preventing L-L self-association and resulting in functionally active RNA-dependent RNA polymerase.[L] (Mus musculus) PubMed

 2399.

genetic analysis revealed that amino acids 238-266 of V protein were necessary for efficient RNA binding and overlapped with residues (238-278) required for maximal repression induced by the C-terminal domain.[V protein] (Mus musculus) PubMed

 2400.

V protein was found to repress reporter activity. Two regions of the polypeptide contributed to this repressive effect including the carboxy-terminus and a region conserved in morbillivirus V proteins located between amino acids 110-131 [V] (Mus musculus) PubMed

 2401.

results show that the codon for amino acid 522 of the MV N protein plays an important role in both in vitro and in vivo viral fitness (Mus musculus) PubMed

 2402.

These results indicate that the putative NES (nuclear export sequence) is functional and that C protein has the ability to shuttle between the nucleus and the cytoplasm. [C protein] (Mus musculus) PubMed

 2403.

Using the two-hybrid system and co-affinity purification experiments, we identified STAT1 and Jak1 as interactors of MV-V and demonstrate that MV-V can block the direct phosphorylation of STAT1 by Jak1. [V protein] (Mus musculus) PubMed

 2404.

We concluded that one mutation, of the histidine at position 1042 of p150, was essential for the ts phenotype of the KRT strain. [P150] (Mus musculus) PubMed

 2405.

The interaction of measles virus V protein with STAT2 is carried by the cysteine-constrained peptide of 49 amino acids localized in the VCT region, and is essential to the inhibition of IFN-alpha/beta signaling.[V] (Mus musculus) PubMed

 2406.

experiments demonstrated that mannose-binding lectin (MBL) binds to envelope glycoprotein resulting in important biological effects and suggest that MBL can interact with filoviruses during infection in humans [Env protein] (Mus musculus) PubMed

 2407.

crystal structure of proteinase-K-resistant domain within the P phosphoprotein [P phosphoprotein] (Mus musculus) PubMed

 2408.

self-association domain of phosphoprotein of Indiana serotype plays a critical role in vesicular stomatitis virus transcription. (Mus musculus) PubMed

 2409.

a specific sequence in VSV G protein, comprising the residues 145 to 164, directly involved in membrane interaction and fusion.[G glycoprotein] (Mus musculus) PubMed

 2410.

Taking these results together, we conclude that the N-terminal 11 to 30 aa are required for N(0)-P complex formation but the N-terminal 210 aa are required for genome RNA encapsidation. [N protein, P protien] (Mus musculus) PubMed

 2411.

p37-1 is a substrate for p40 production catalyzed by heparin-sensitive PK (protein kinase) in animal cells [P protein] (Mus musculus) PubMed

 2412.

cloned and sequenced the nucleoprotein gene[Rabies virus 5aG strain, Nucleoprotein ] (Mus musculus) PubMed

 2413.

the localization of the nuclear localization signal and the CRM1-dependent nuclear export signal determines the cellular distribution of the P gene products [P protein] (Mus musculus) PubMed

 2414.

phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3 [P protein] (Mus musculus) PubMed

 2415.

Rabies virus P protein does not induce STAT1 degradation and does not interfere with STAT1 phosphorylation. (Mus musculus) PubMed

 2416.

N-terminal sequencing and mass spectrometry analysis identified a phosphhoprotein peptide containing residues 4-40 that binds to nucleoprotein and keeps it soluble [Phosphoprotein P] (Mus musculus) PubMed

 2417.

phosphoprotein P inhibits interferon signaling via activation- dependent binding to STAT1 and STAT2 [phosphoprotein P] (Mus musculus) PubMed

 2418.

products of the rabies virus P gene are able to counteract IFN signaling by creating both cytoplasmic and nuclear blocks for STAT1.[P protein] (Mus musculus) PubMed

 2419.

an amino acid at position 95 of the matrix protein is a cytopathic determinant of the rabies virus and the cytopathic effect is, at least partly, due to apoptosis (Mus musculus) PubMed

 2420.

results show NGF but not NT-3 caused increase of P protein & accumulation in neuronal bodies, revealing change in transport to neuritic processes; work shows part of cellular mechanisms regulating P protein expression during the viral cycle [P protein] (Mus musculus) PubMed

 2421.

results suggest a conserved organization of P proteins in the Rhabdoviridae family in concatenated functional domains resembling that of the P proteins in the Paramyxoviridae family[P protein] (Mus musculus) PubMed

 2422.

sequence of the 1918 influenza virus polymerase genes, PB1, PB2, and PA [PB1] (Mus musculus) PubMed

 2423.

We demonstrated that the direct binding of the NS1A protein to the N-terminal 230 amino acid region of PKR inhibits PKR activation by PACT and dsRNA [Ns1A, A/Udorn/72] (Mus musculus) PubMed

 2424.

hemagglutinin structure at 2.9 angstrom resolution; receptor specificity of mutations [hemagglutinin, H5N1 influenza virus A/Vietnam/1203/2004] (Mus musculus) PubMed

 2425.

results show that NS1 protein from human H5N1 influenza isolate A/HK/156/97 reduces both systemic and pulmonary pro-inflammatory cytokines in an in vivo mouse model and protects against bone marrow lymphocyte depletion [NS1] (Mus musculus) PubMed

 2426.

Data suggest that the primary role of double-stranded RNA binding by the NS1A protein in virus-infected cells is to sequester dsRNA away from RNAse L. (Mus musculus) PubMed

 2427.

Data show that protonation of the third of four imidazoles coincides with acid activation of M2 and that, at physiological pH, the channel is closed by two imidazole-imidazolium dimers, each sharing a low-barrier hydrogen bond. (Mus musculus) PubMed

 2428.

N-terminal region of PA is involved in multiple functions of the polymerase, including protein stability, endonuclease activity, cap binding, and promoter binding. (Mus musculus) PubMed

 2429.

Knocking out the PB1-F2 protein had no effect on viral replication in tissue culture but diminished virus pathogenicity and mortality in mice. (Mus musculus) PubMed

 2430.

the M2 protein cytoplasmic tail is a crucial mediator of infectious virus production binding through its cytoplasmic tail to M1 protein. (M2 protein) (M1 protein) (Mus musculus) PubMed

 2431.

Results report that influenza A virus NS1 binds directly to p85beta, a regulatory subunit of phosphatidylinositol-3-kinase (PI3K), but not to the related p85alpha subunit [NS1]. (Mus musculus) PubMed

 2432.

The bipartite nuclear localization signal, but not the unconventional nuclear localization signal, of NP is essential for influenza A virus replication (NP). (Mus musculus) PubMed

 2433.

Mutations at positions 182 and 192 independently convert the HAs of H5N1 viruses known to recognize the avian receptor to ones that recognize the human receptor [HA] (Mus musculus) PubMed

 2434.

3.2 A crystal structure of nucleoprotein [NP] (Mus musculus) PubMed

 2435.

PB1-F2 specifically targets and destroys alveolar macrophages [PB1-F2 protein] (Mus musculus) PubMed

 2436.

NS1 not only blocks but also activates signaling pathways to ensure efficient virus replication (Mus musculus) PubMed

 2437.

The data suggest that PB2 might play a pivotal role in molecular interactions involving both the viral nucleoprotein and cellular proteins. [PB2 protein] (Mus musculus) PubMed

 2438.

two amino acid mutations in the hemagglutinin that cause a switch in receptor binding preference resulted in a virus incapable of respiratory droplet transmission between ferrets [hemagglutinin, H1N1 virus] (Mus musculus) PubMed

 2439.

An independently folded C-terminal domain from PB2 was identified and its solution structure was determined by NMR. Both the domain and the full-length PB2 subunit are efficiently imported into the nucleus. (Mus musculus) PubMed

 2440.

the direct binding of PKR to the NS1 protein in vitro that results in inhibition of PKR activation requires the NS1 123-127 amino acid sequence [NS1] (Mus musculus) PubMed

 2441.

Here we show that influenza virus PA causes the specific degradation of the hypophosphorylated form of the largest subunit of RNAP II without affecting the accumulation of its hyperphosphorylated forms.[PA] (Mus musculus) PubMed

 2442.

It is likely that the evolutionarily well-conserved nucleolar targeting function of nonstructural protein 1 (NS1A protein) plays a role in the pathogenesis of influenza A virus. [NS1A] (Mus musculus) PubMed

 2443.

The NS1 protein down-regulates the splicing and blocks the nuclear export of its own viral mRNA (NS1). (Mus musculus) PubMed

 2444.

We molecularly characterized the hemagglutinin (HA) and neuraminidase (NA) genes of the A/China/GD01/06 (GD01) strain causing the human H5N1 infection. [HA] (Mus musculus) PubMed

 2445.

results demonstrate that both NLS1 and NLS2 on NP can mediate the nuclear uptake of influenza A vRNPs [NP] (Mus musculus) PubMed

 2446.

The extracellular and cytoplasmic domains of M2 protein were not essential for ion channel activity of M2 protein. [M2 protein] (Mus musculus) PubMed

 2447.

We conclude that the L163-I178 region of PA is directly or indirectly involved in cRNA promoter binding and suggest a novel function for RNA polymerase PA subunit in modulating promoter binding. [PA] (Mus musculus) PubMed

 2448.

It was found that the D92E mutation could result in weakened interactions of the carboxylate side chain with other phosphorylated residues, thereby activating phosphorylation of NS1 [NS1] (Mus musculus) PubMed

 2449.

the deletion of amino acids 191 to 195 of the NS1 protein is critical for the attenuation of the SW/FJ/03 virus in chickens and that this deletion affects the ability of the virus to antagonize IFN induction in host cells. (Mus musculus) PubMed

 2450.

The results suggest that G8 as well as E11 play an important functional and structural role in membrane fusion and that the polarity of E11 is crucial for fusion activity.[A/chicken/Fujian/1042/2005 (H5N1) strain] (Mus musculus) PubMed

 2451.

NS1 protein is critical for the pathogenicity of H5N1 influenza viruses in mammalian hosts and that the amino acid S42 of NS1 plays a key role in undermining the antiviral immune response of the host cell.[NS1 in A/Duck/Guangxi/27/03 strain] (Mus musculus) PubMed

 2452.

the side-chain conformation and position of Trp41 differs significantly in the two pH-dependent states of the proton channel of M2TMD.(M2TMD) (Mus musculus) PubMed

 2453.

study identified a region of conserved basic amino acids near the C-terminus of PB1 involved in regulating viral transcription. [PB1] (Mus musculus) PubMed

 2454.

the structure of the tetrameric M2 channel in complex with rimantadine, determined by NMR [M2] (Mus musculus) PubMed

 2455.

crystal structure of the transmembrane-spanning region of the homotetrameric M2 protein in the presence and absence of the channel-blocking drug amantadine [M2] (Mus musculus) PubMed

 2456.

in vivo formation and in vitro renaturation of the N5D3 epitope depend on inter-subunit interactions of monomeric NPs and NP-NP interactions influence the antigenic structure of the influenza virus NP polymers.[NP] (Mus musculus) PubMed

 2457.

Our data indicate that NA alone among viral proteins limits influenza A virus superinfection.[NA] (Mus musculus) PubMed

 2458.

NS1 sequences from the 1918 H1N1 and H5N1 highly pathogenic avian influenza viruses demonstrated increased virulence in infected mice compared with wt A/WSN/33 virus [NS1] (Mus musculus) PubMed

 2459.

the enzymatic properties and crystal structures of neuraminidase mutants from H5N1-infected patients that explain the molecular basis of resistance [neuraminidase] (Mus musculus) PubMed

 2460.

We report a crystal structure for the NS1 effector domain of avian influenza virus A/Duck/Albany/76,and show that tryptophan-187 (a residue located at the helix-helix interface) is essential for dimerization of this effector domain. [NS1] (Mus musculus) PubMed

 2461.

Phylogenic analysis of the matrix (M) genes of 67 strains revealed that A/duck/Hokkaido/W95/2006 (H10N8) was a reassortant virus. (Mus musculus) PubMed

 2462.

Coarse-grained molecular dynamics (CG-MD) simulations have been used to explore partitioning into a membrane of M2 transmembrane helices during bilayer self-assembly from lipids.[M2 protein] (Mus musculus) PubMed

 2463.

X-ray structure of the full-length NS1 from an H5N1 strain (A/Vietnam/1203/2004) that was associated with 60% of human deaths in an outbreak in Vietnam [NS1] (Mus musculus) PubMed

 2464.

An in-depth analysis of M2 channel was performed for its functional studies, particularly for the mutations D44N, D44A and N44D on position 44, and the mutations on positions 27-38. (Mus musculus) PubMed

 2465.

The authors conclude that M1 probably interacts with membranes via multiple binding sites.[M1 in strain A/FPV/Rostock/34] (Mus musculus) PubMed

 2466.

The data suggest that CDK/ERK-mediated phosphorylation of NS1 at threonine-215 is important for efficient virus replication. (Mus musculus) PubMed

 2467.

These results indicate that the PB2 protein restricts the growth of Ck/Yamaguchi/04 (H5N1) in pigs.[PB2 in strain Ck/Yamaguchi/04] (Mus musculus) PubMed

 2468.

Phylogenetic analysis shows that two distinct gene pools, corresponding to both NS allele A and B, were present in the mallard populations in Northern Europe. [NS] (Mus musculus) PubMed

 2469.

The different protonation states of the His-37 residues of the M2 bundle in a bilayer was explored using molecular dynamics (MD) simulations.[M2 protein] (Mus musculus) PubMed

 2470.

The authors demonstrated an interaction between PA and PB2 that has not been reported previously.[PA & PB2 in strain H1N1 A/WSN/33] (Mus musculus) PubMed

 2471.

The data show that residues comprising the fusion peptide pocket are important in triggering pH-dependent activation of the H5 HA protein.[HA in strain A/chicken/Vietnam/C58/04 (H5N1)] (Mus musculus) PubMed

 2472.

biochemical and structural studies showing that the amino-terminal 209 residues of the PA subunit contain the endonuclease active site; this domain has intrinsic RNA and DNA endonuclease activity that is strongly activated by manganese ions [PA] (Mus musculus) PubMed

 2473.

The 1918 PB2 protein was found to be both necessary and sufficient for airborne transmission of a virus expressing the 1918 HA and neuraminidase [HA & PB2] (Mus musculus) PubMed

 2474.

The data suggest that protein kinase C contributes to the phosphorylation of influenza PB1 and NS1 proteins which appears to be functionally relevant for both viral RNA polymerase activity and efficient viral replication.[PB1 & NS1 in A/WSN/33 virus] (Mus musculus) PubMed

 2475.

A role for the NS2/NEP protein in the regulation of influenza virus transcription and replication that is independent of its viral RNP export function is proposed.[NS2/NEP] (Mus musculus) PubMed

 2476.

A wide range of complexes of influenza A neuraminidases with inhibitor molecules (sialic acid derivatives & others) have been analyzed; strongest interactions of the residues are with the acidic group at the C2 position of the inhibitor [neuraminidase] (Mus musculus) PubMed

 2477.

NS1 truncated mutant demonstrated limited viral replication and enhanced type I IFN induction. (Mus musculus) PubMed

 2478.

High degree of conservation in the NS1 and NS2 were found among influenza A virus subtypes. [NS1, NS2] (Mus musculus) PubMed

 2479.

The results showed that a siRNA targeting influenza M2 gene (siM2) potently inhibited viral replication.[M2 protein] (Mus musculus) PubMed

 2480.

The expression of N40, PB1-F2, and PB1 are interdependent, and certain mutations ablate PB1-F2 production affected N40 accumulation. [N40] (Mus musculus) PubMed

 2481.

NF90 inhibits influenza virus replication during the early phase of infection through direct interaction with viral NP. [NP] (Mus musculus) PubMed

 2482.

ESI-MS analysis and cellular expression of PB1-F2 mutants identified the positions Ser-35 as the major and the Thr-27 as an alternative PKC phosphorylation site.[PB1-F2] (Mus musculus) PubMed

 2483.

Functional data on M2 proton channel activity and high-resolution structural information available describing the transmembrane domain are summarized. (Mus musculus) PubMed

 2484.

Molecular dynamics (MD) simulations of the M2 transmembrane domain (TMD) in the absence and presence of the antiviral drug amantadine, is reported.[M2 protein] (Mus musculus) PubMed

 2485.

Analysis of 391 influenza A (H1N1) viruses identified a previously undescribed Gln136Lys (Q136K) neuraminidase mutation conferring zanamivir resistance (confirmed using reverse genetics). [NA] (Mus musculus) PubMed

 2486.

M1 blocked the interaction between C1qA and heat-aggregated IgG in vitro and inhibited haemolysis.[M1] (Mus musculus) PubMed

 2487.

The nucleoprotein (NP) displayed very slow mobility that significantly increased on formation of transcriptionally active viral ribonucleoproteins. (Mus musculus) PubMed

 2488.

These results show that a highly pathogenic avian influenza virus can be attenuated by modulating the caspase cleavage sites of NP and M2.[NP and M2] (Mus musculus) PubMed

 2489.

The HA1 protein of swine H1N1/N2 viruses and the new A/H1N1 of viruses differed in conserved characteristics that reflect a distinct propensity of these viruses to undergo a specific interaction with swine or human host proteins or receptors. (Mus musculus) PubMed

 2490.

This is the first study showing that the isoleucine residue at position 97 in PA plays a key role in enhanced virulence in mice and is implicated in the adaptation of avian influenza viruses to mammalian hosts. (Mus musculus) PubMed

 2491.

Ataxin 10 and eukaryotic initiation factors interacts with M2 protein of influenza A virus. (Mus musculus) PubMed

 2492.

Loss of a single N-linked glycan from the hemagglutinin of influenza virus (H3N2 strain A/Beijing/353/89) is associated with resistance to collectins and increased virulence in mice. (Mus musculus) PubMed

 2493.

RVFV NSm protein is the first identified Phlebovirus protein that has an antiapoptotic function. [NSm protein] (Mus musculus) PubMed

 2494.

Molecular-mass measurements suggest a G(N)-G(C) heterodimer as the most likely candidate for the capsomers.[G protein] (Mus musculus) PubMed

 2495.

NSs proteins of the related but less virulent sandfly fever Sicilian virus and La Crosse virus, in contrast, had no such anti-double-stranded RNA-dependent protein kinase(PKR) activity despite being efficient suppressors of IFN induction[ PKR] (Mus musculus) PubMed

 2496.

Hydrophobic region of glycoprotein C(GP-C) signal peptide is sufficient for the membrane insertion of GP-C, while both hydrophobic regions are required for the processing and cell surface expression of the GPs.(Glycoprotein C) (Mus musculus) PubMed

 2497.

The results showed that of the substituted residues, only H1189 and D1329 appeared to be critically involved in binding Z.[Z protein] (Mus musculus) PubMed

 2498.

Interaction between Z and N is required for assembly of the nucleocapsids and the glycoproteins into infectious arenavirus budding particles. [Z protein] (Mus musculus) PubMed

 2499.

These results indicate that tacaribe virus Z protein utilizes a budding mechanism distinct from that reported for other arenaviruses. (Mus musculus) PubMed

 2500.

results suggest that the mutated residues of may not be responsible for the higher pH optimum of HFV protease, but they may contribute to the lower dimer stability as compared with that of HIV-1 protease [protease] (Mus musculus) PubMed

 2501.

Biologic activity of equine infectious anemia virus (EIAV) surface (SU) glycoprotein was assayed in a mouse model. [SU] (Mus musculus) PubMed

 2502.

These results demonstrate that S2 gene expression is essential for disease expression of EIAV. (Mus musculus) PubMed

 2503.

3D structure of 37-aa peptide from lentiviral EIAV nucleocapsid, complexed with zinc, contains 2 zinc binding domains held together by 5-residue basic linker Arg(38)-Ala-Pro-Lys-Val(42) that allows for spatial proximity between 2 finger domains[NCp11] (Mus musculus) PubMed

 2504.

Epitope analysis of the p26 EIAV core protein. [p26] (Mus musculus) PubMed

 2505.

Cytoplasmic tail truncation of EIAV env protein can cause an increase in the ability to induce cell death by mitochondria mediated necrosis within the env expressing cells. [Env] (Mus musculus) PubMed

 2506.

Mutations in the S2 of the EIAV vaccine strains did not significantly alter the viral replication in vitro. [S2] (Mus musculus) PubMed

 2507.

The design of several peptides derived from the FIV envelope protein gp36, their homology to HIV gp41, and the residues of the C-terminal region that are critical for interaction with the N-terminal region are reported.[gp36] (Mus musculus) PubMed

 2508.

Severevirus attenuation for both replication and pathogenicity exhibited by a vif-deleted FIV mutant is similar for both neonatal and adult hosts. [fiv protein] (Mus musculus) PubMed

 2509.

The analyses revealed alterations in genes critical for RNA post-transcriptional modifications and protein ubiquitination as the two most significant functional outcomes of OrfA expression. [OrfA] (Mus musculus) PubMed

 2510.

P59 insertion between the lipid headgroups leads to significant liposome destabilization[glycoprotein gp36 ] (Mus musculus) PubMed

 2511.

FIV is displaying relative little sequence variation during infection of its host, both in the env and the orfA gene [OrfA] (Mus musculus) PubMed

 2512.

HIV-1-gp120 may predispose resting CD4(+)T cell to bystander CD95-mediated apoptosis and support the key role of ezrin/CD95 linkage in regulating susceptibility to CD95-mediated apoptosis [HIV-1 gp120]. (Mus musculus) PubMed

 2513.

the role of the HIV-1 nucleocapsid protein p7 (NCp7) in the fate of the HIV-1 full length RNA from genomic RNA in a dimeric form to the proviral DNA.[NCP7] (Mus musculus) PubMed

 2514.

Transcription, splicing, steady state RNA levels, and pr55Gag processing were not affected in hnRNP A2 HIV-1. (hnRNP A2) (Mus musculus) PubMed

 2515.

Evolution of the HIV-1 V3 loop was monitored in 15 HIV subjects; recombination was detected in many of the sequences. (Glycoprotein 120 in HIV-1) (Mus musculus) PubMed

 2516.

These studies suggest that gp120 may induce neuronal apoptosis in the CNS of HIV-associated dementia patients through the CXCR4-NADPH oxidase-superoxide-NSMase-ceramide pathway. [gp120] (Mus musculus) PubMed

 2517.

gp120 has the capacity to dysregulate the vast CD4+ T cell population that expresses CXCR4 and may exploit its chemotactic properties to retain potential target cells and locally perturb their cytoskeleton, facilitating viral transmission. (gp120 env) (Mus musculus) PubMed

 2518.

The ability of CD4 antigen-primed gp120 to block stromal cell-derived factor 1 (SDF-1) signaling in mouse neural progenitors may contribute to the neuropathological effects of HIV-1. (envelope surface glycoprotein gp120) (Mus musculus) PubMed

 2519.

Efavirenz binds to HIV-1 reverse transcriptase predominantly through strong electrostatic interaction with the Lys101 residue. (reverse transcriptase) (Mus musculus) PubMed

 2520.

Two C3d elements are able to elicit gp120 binding antibodies more efficiently than gp120 lacking C3d moieties. (gp120) (Mus musculus) PubMed

 2521.

Toward the end of the asymptomatic period there was a change in the V3-loop structure or in the environment surrounding the V3 loop, possibly because of its proximity to the gp120 core. (gp120) (Mus musculus) PubMed

 2522.

Two soluble trimeric recombinant gp41 proteinscan interfere with multiple steps of the HIV entry process. (gp41 protein) (Mus musculus) PubMed

 2523.

gp120 may elicit polyclonal IgG and IgA responses by linking the innate and adaptive immune systems through the B cell-activating factor of the TNF family [gp120] (Mus musculus) PubMed

 2524.

p24 may be an accurate low-cost alternative to monitor antiviral agents in pediatric HIV-1 infections (HIV-1 p24 antigen) (Mus musculus) PubMed

 2525.

Integrase is an efficient mediator of DNA nuclear import in vitro and implies the potential for IN to fulfil such a role in vivo [IN] (Mus musculus) PubMed

 2526.

The results establish a molecular mechanism for LEDGF/p75-mediated tethering of HIV-1 integrase to chromatin. [HIV-1 Integrase] (Mus musculus) PubMed

 2527.

Frequency of K65R in combination with thymidine-analogue mutations at the genomic level of HIV-1[HIV-1 reverse-transcriptase] (Mus musculus) PubMed

 2528.

correlate with deletion studies mapping the domain and subdomain boundaries of reverse transcriptase and integrase [integrase] (Mus musculus) PubMed

 2529.

hydration sites study and a detailed analysis of the solvation of the nucleotide binding site are also presented[ reverse transcriptase] (Mus musculus) PubMed

 2530.

Two regions within the enzyme involved in the interaction with LEDGF/p75, were identified and characterised.[HIV-1 integrase] (Mus musculus) PubMed

 2531.

The study focused on the recognition step and examined possible peptide-peptide interactions between various principle neutralizing determinant (PND)-derived peptides from the V3-loop and the N-terminal (Nt) domain of CCR5. (Mus musculus) PubMed

 2532.

could be applied for the characterization of gp41 conformers for use in immunological screening of antigens[gp41] (Mus musculus) PubMed

 2533.

Stimulation of two receptors together, using gp120, a component of HIV enhanced cell adhesion greater than stimulation of CD4 or CXCR4 individually. (gp120) (Mus musculus) PubMed

 2534.

These data reveal that HIV-1 can escape from an inhibitor of viral entry by acquiring mutations that cause the cytoplasmic tail of gp41 to be cleaved by the viral protease. (Mus musculus) PubMed

 2535.

When bound to lipid bilayers at low concentration, the HIV fusion domain is also largely alpha-helical, as determined by CD and FTIR spectroscopy. [gp41 HIV fusion protein] (Mus musculus) PubMed

 2536.

transmembrane protein gp41 in virus replication (Mus musculus) PubMed

 2537.

Studies with P-TEFb inhibitors demonstrate a loss of the large form of P-TEFb within the cell and a concomitant reduction in HIV-1 infectivity/ {P-TEFb] (Mus musculus) PubMed

 2538.

von Hippel-Lindau binding protein and cullin2/von Hippel-Lindau are required for proper HIV-1 expression at a step between integrase-dependent proviral integration into the host genome and transcription of viral genes[integrase] (Mus musculus) PubMed

 2539.

The first part of the NHR domain could be involved in the first steps of the destabilization of the HIV-1 gp41 six-helix bundle after its interaction with negatively charged phospholipid headgroups.[gp41] (Mus musculus) PubMed

 2540.

Diketoacid (DKA) compounds have been shown to inhibit HIV-1 integrase by a mechanism that involves sequestration of the active site metals. (Mus musculus) PubMed

 2541.

Double-stranded RNA-activated protein kinase (PKR) is involved in HIV/glycoprotein 120-associated neurodegeneration. [gp120; glycoprotein 120] (Mus musculus) PubMed

 2542.

Chronic alcohol drinking augmented the adverse effects of HIV-1 gp120 possibly by suppressing its degradation in hepatocytes. (Mus musculus) PubMed

 2543.

[p16 pol gene product]report two high-resolution crystal structures of wild-type protease (Mus musculus) PubMed

 2544.

CBD1 but not CBD2 binds cells and forms large aggregates at the plasma membrane by colocalizing with cytofacial caveolin-1.[gp41] (Mus musculus) PubMed

 2545.

The sensitivities of the R5X4 strain to coreceptor inhibitors were altered by a single amino acid substitution in the V3 region of gp120.[gp120] (Mus musculus) PubMed

 2546.

N-acetyl-LWYIK-amide (LWYIK) represents the naturally-occurring CRAC motif segment in the pretransmembrane region of the gp41 protein of HIV-1. (Mus musculus) PubMed

 2547.

The interaction between residues 322 and 440 of gp120 may serve as part of the molecular switch for HIV-1 phenotype conversion. (Mus musculus) PubMed

 2548.

HIV-1 and gp120 can induce breast cancer cell apoptosis through gp120-CXCR4 interaction without a CD4-induced conformational change of gp120 [gp120] (Mus musculus) PubMed

 2549.

p17 induces immature circulating plasmacytoid dendritic cells to home in lymph nodes devoid of their ability to serve as a link between innate and adaptative immune systems.[p17] (Mus musculus) PubMed

 2550.

the loss of the N448 glycan induces structural changes in the C4 region of gp120 that make this specific region more resistant to proteolytic processing, thereby restricting the generation of CD4 T cell epitopes from this region [gp120] (Mus musculus) PubMed

 2551.

detailed understanding of the molecular interactions mediating the immunosuppressive activity of the FP(5-13) motif should facilitate evaluating its contribution to HIV pathology and its exploitation as an immunotherapeutic tool[gp41] (Mus musculus) PubMed

 2552.

Wild type HIV-1 reverse transcriptase (RT) indeed catalyzes incorporation of deoxynucleoside diphosphates (dNDP) substrates whereas RT with mutations of residue K65 were unable to catalyze this reaction.[Reverse transcriptase] (Mus musculus) PubMed

 2553.

Derivatives of Gag p24(19-27) and Gag p17(77-85) cytotoxic T cell (CTL) epitopes are identified that induce cross reactive anti-HIV-1 CTL responses against naturally occurring mutants in lymphocytes primed ex vivo and in HLA-A2 transgenic mice in vivo. (Mus musculus) PubMed

 2554.

HIV-1 glycoprotein 120 can up-regulate multidrug resistance protein Mrp1, but not Mrp4, functional expression in cultured astrocytes. [glycoprotein 120; gp120] (Mus musculus) PubMed

 2555.

The solution structures of complexes between calcium-saturated calmodulin (Ca (2+)/CaM) and a CaM-binding domain of the HIV-1 matrix protein p17 have been determined by small-angle X-ray scattering.[p17] (Mus musculus) PubMed

 2556.

Ncp7 protetin in HIV-1 shows considerable conformational lability [NCP& protein, HIV-1] (Mus musculus) PubMed

 2557.

The interactions between two beta-strands that are important for the formation and/or integrity of the beta-barrel can be supported by either a disulfide bond or beta-sheet favoring residues.[Gp120] (Mus musculus) PubMed

 2558.

NMR studies show that NCp7(12-55) and NCp7(1-55) interact at the 5' end of the loop of DeltaP(-)PBS, a (-)PBS (primer-binding site) derivative without the 3' protruding sequence, in a slow-exchange equilibrium.[Ncp7] (Mus musculus) PubMed

 2559.

The interaction of HIV-1 viral glycoprotein gp120 with the tyrosine-sulfated amino-terminus of human CCR5 is critical to the entry of HIV-1 into the cell, and has been characterized at the thermodynamic level. (Mus musculus) PubMed

 2560.

The trimeric membrane-proximal external region structure represents the prefusion conformation of gp41, preceding the putative prehairpin intermediate and the postfusion trimer-of-hairpins structure.[gp41] (Mus musculus) PubMed

 2561.

The structure of HIV-1 protease in complex with transition-state analog KNI-272 was determined by combined neutron crystallography at 1.9-A resolution and X-ray crystallography at 1.4-A resolution.[HIV-1 protease] (Mus musculus) PubMed

 2562.

the RNA recognition mechanism for NCp8 is different from that of NCp7 and that the hydrophobic cleft in the second zinc finger acts as a secondary active domain instead of the 3(10) helix in NCp7 [NCp7] (Mus musculus) PubMed

 2563.

Two IN dimers individually assemble on U3 and U5 DNA sequence ends before the non-covalent juxtaposition of two viral DNA ends, producing the synaptic complex.[Integrase] (Mus musculus) PubMed

 2564.

The data suggest that in addition to facilitating annealing of tRNA(Lys3) to the primer binding site and possible denaturation of the primer activation signal, other functions of nucleocapsid p7 (NCp7) involved in annealing are required.[NCp7] (Mus musculus) PubMed

 2565.

gp105 suppresses activation of T cells through a monocyte-mediated mechanism. The TLR4 pathway is likely involved, since gp105 activates TLR4 signaling and induces TNF-alpha production by monocytes. gp105. (Mus musculus) PubMed

 2566.

results show for the first time that Vpu proteins from SIV(cpz)isolates, although diverse in sequence & predicted secondary structure from the HIV-1 subtype B protein, are capable of down-regulating CD4 [Vpu] (Mus musculus) PubMed

 2567.

the accessory factor, vpr, behaves similarly to the essential lentiviral genes tat and env [vpr] (Mus musculus) PubMed

 2568.

NAF may play a role in modulating host cell gene expression during MMTV infection. [NAF, negative acting factor] (Mus musculus) PubMed

 2569.

Adventitial monocytes/macrophages are source of factor XIII in tissue-type transglutaminase(tTG)-null mice and contribute to an alternative, delayed mechanism of inward remodeling when tTG is absent. (Tissue-type transglutaminase, factor III) (Mus musculus) PubMed

 2570.

Myostatin is dynamically regulated in the heart and acts more broadly than previously appreciated to regulate growth of multiple types of striated muscle. (Myostatin) (Mus musculus) PubMed

 2571.

Recognition that p66shc conditions destiny of cardiac progenitor cells(CPCs) raises possibility that diabetic cardiomyopathy is stem cell disease in which abnormalities in CPCs define life and death of heart. (Mus musculus) PubMed

 2572.

Identification of the segment of the MMTV genome which represents the binding site for Rem protein and is required for export of the unspliced viral RNA transcripts (Rem). (Mus musculus) PubMed

 2573.

mutations in SU protein alter disease pathogenesis [SU protein] (Mus musculus) PubMed

 2574.

RNase H primer grip is an important determinant of in vivo fidelity of DNA synthesis [reverse transcriptase (RT)] (Mus musculus) PubMed

 2575.

intracellular expression of the env N-terminal heptad repeat region inhibited fusion by efficiently blocking proteolytic processing and intracellular transport of the envelope protein [env] (Mus musculus) PubMed

 2576.

C-terminal disulfide-bonded loop of murine leukemia virus SU protein invovled in a postbinding step critical for viral entry [SU protein] (Mus musculus) PubMed

 2577.

crystal structure at 1.6-Angstroms resolution of RNaseH was determined [RNase H] (Mus musculus) PubMed

 2578.

correlate with deletion studies mapping the domain and subdomain boundaries of reverse transcriptase and integrase [RNase H and integrase] (Mus musculus) PubMed

 2579.

transmembrane peptides bind to Env arrested at intermediate stage of activation by alkylation of the isomerization-active thiol in the surface subunit; this inhibits fusion rescue by dithiothreitol-mediated reduction of surface protein-TM disulfide [env] (Mus musculus) PubMed

 2580.

Data indicate a possible mechanism by which the membrane-proximal domain in Moloney murine leukemia virus glycoprotein Env may affect the formation of membrane fusion intermediates. [Env] (Mus musculus) PubMed

 2581.

Abl protein contribute to proper localization by playing a dominant role in trafficking of the v-Abl molecule[v-Abl protein ] (Mus musculus) PubMed

 2582.

Random and site-directed mutagenesis in combination with high-temperature activity screens were used to identify multiple point mutations that collectively increase the half-life of reverse transcriptase at elevated temperature (reverse transcriptase). (Mus musculus) PubMed

 2583.

NMR assignment of WT matrix protein and its R55F mutant from Mason-Pfizer monkey virus (Mus musculus) PubMed

 2584.

Nucleocapsid-free dUTPase (48 426 Da) was cocrystallized with a dUTP substrate analogue using the hanging-drop vapour-diffusion method. (deoxy UTPase) (Mus musculus) PubMed

 2585.

These results show clearly that the proposed redox mechanism does not rely solely on the formation of the stabilizing S-S bridge in the protease.[M-PMV protease] (Mus musculus) PubMed

 2586.

The oligomeric properties of betaretroviral nonmyristoylated matrix protein (MA) and its R55F mutant from the Mason-Pfizer monkey virus in solution were studied by means of chemical crosslinking and NMR spectroscopy.[MA] (Mus musculus) PubMed

 2587.

Integrase has evolved to have submaximal processing activity so that it can also catalyze DNA joining. [integrase] (Mus musculus) PubMed

 2588.

the conserved 35-amino-acid spacing is not absolutely required for enzymatic activity, but the correlation between infectivity and Mg(2+)-dependent activity supports magnesium as the metal cofactor used by integrase in vivo (integrase) (Mus musculus) PubMed

 2589.

We first used molecular modelling to predict that the gp30 minimal fusion peptide corresponds to the 15 first residues. (gp30) (Mus musculus) PubMed

 2590.

Understanding the mechanism of how cleavage of IGFBP-5 by this protease (IGFBPase) alters its activity will help to further our understanding of the biologic actions of the IGFs [IGFBPase] (Mus musculus) PubMed

 2591.

p12 could replace Nef in HIV-1, and reconstitute virus replication in HIV-1 infected Magi-CCR5 cells or macrophages. [HTLV-1p12] (Mus musculus) PubMed

 2592.

p12I isdispensable for the transmission and maintenance of HTLV-I infection [P12I protein] (Mus musculus) PubMed

 2593.

Data show that depletion of hCAP-D2 affects chromosome alignment in metaphase and delays entry into anaphase, suggesting that condensin I is involved in the correct attachment between kinetochores and the mitotic spindle [hCAP-D2]. (Mus musculus) PubMed

 2594.

data indicate that p12I appears to play a vital role in HTLV-1-mediated T cell activation by activating calcium-mediated transcription and augmenting the amounts of p300 within T lymphocytes [p12I] (Mus musculus) PubMed

 2595.

p30II functions as a novel retroviral modulator of Myc-TIP60-transforming interactions that may contribute to adult T-cell leukemogenesis. (Mus musculus) PubMed

 2596.

some genetic markers were recognized in association with isolates from HTLV-1a subgroup B and Brazilian HTLV-1aA strains [p12I protein] (Mus musculus) PubMed

 2597.

Results highlight the centrosome as a site to organize phosphorylation of Cep55 by Erk2/Cdk1 and Plk1, enabling it to relocate to the midbody to function in mitotic exit and cytokinesis [Cep55]. (Mus musculus) PubMed

 2598.

Tax1 protected CD34(+) cells from serum withdrawal-mediated apoptosis. (tax1) (Mus musculus) PubMed

 2599.

report the structure of a complex of human T cell leukemia virus type 1 (HTLV-1) protease with a substrate-based inhibitor bound in subsites P5 through P5' (Mus musculus) PubMed

 2600.

Expression of HTLV-1 Tax may lead to immune escape of infected T cells and, thus, to persistent infection and transformation. (TAX) (Mus musculus) PubMed

 2601.

Growth-promoting activity of HBZ RNA likely plays an important role in oncogenesis by HTLV-I. (HBZ = basic leucine zipper factor) (Mus musculus) PubMed

 2602.

HBZ was not required for in vitro cellular immortalization, but enhanced infectivity and persistence. (HBZ protein) (Mus musculus) PubMed

 2603.

data show the presence of a novel isoform of HBZ in adult T-cell leukemia cells, and in addition, shed new light on the possibility that each isoform may play a unique role in distinct regions in the cell nucleus[HBZ] (Mus musculus) PubMed

 2604.

Tax-mediated dendritic cell gene regulation might play a critical role in cellular activation and the mechanisms resulting in HTLV-1-induced disease. (Tax) (Mus musculus) PubMed

 2605.

indicate that HTLV-1 p12(I), in addition to enhancing T cell activation, promotes cell-to-cell spread by inducing LFA-1 clustering on T cells via calcium-dependent signaling [p12I1] (Mus musculus) PubMed

 2606.

Molecular analysis revealed a novel form of a single pigment gene with a unique arrangement of exon 5 (Y277 from the L gene and A285 from the M gene). (Mus musculus) PubMed

 2607.

p30 nuclear/nucleolar retention is mediated through interactions with RNA and a constituent of the 60 S ribosomal subunit [gp30, HTLV-1] (Mus musculus) PubMed

 2608.

tof/p30II interacts with HTLV-1 Rex protein and sequesters Rex/cellular export factor (CRM-1) complexes in the nucleoli [tof; p30II] (Mus musculus) PubMed

 2609.

anti-gp46-197 antibody may be a novel beacon for gauging the efficacy of therapeutic approaches to adult T-cell leukemia/lymphoma [gp46] (Mus musculus) PubMed

 2610.

results suggest that HTLV-I HBZ-SP1- mediated sequestration of JunB to the HBZ-SP1 nuclear bodies may be causing the repression of JunB activity in vivo [HBZ-SP1] (Mus musculus) PubMed

 2611.

p12(I) has contrasting effects on TCR signaling: it down-regulates TCR in a LAT-dependent manner on one hand, and on the other, it increases calcium release in a LAT-independent manner.[p12(I)] (Mus musculus) PubMed

 2612.

review summarizs the molecular and cellular mechanisms involved in the leukemogenesis induced by HTLV-I, focusing particularly on the viral gene HBZ(HBZ) (Mus musculus) PubMed

 2613.

evidence is provided that HBZ/JunD heterodimers interact with Sp1 transcription factors and that activation of hTERT transcription by these heterodimers is mediated through binding sites for Sp1 present in the hTERT promoter.[bZIP] (Mus musculus) PubMed

 2614.

a novel host-virus interaction between a cellular factor XBP-1 and transcriptional regulation of HTLV-1 [XBP-1] (Mus musculus) PubMed

 2615.

Sp1 is critical for sHBZ transcription, which accounts for the constitutive expression of the sHBZ gene (Mus musculus) PubMed

 2616.

Hbz expression enhances the proliferative capacity of HTLV-1-infected T cells, playing a critical role in cell survival and ultimately HTLV-1 tumorigenesis in the infected host. (Hbz) (Mus musculus) PubMed

 2617.

Human T-cell leukemia virus type 1 HBZ protein bypasses the targeting function of ubiquitination [HBZ] (Mus musculus) PubMed

 2618.

HBZ specifically suppressed NF-kappaB-driven transcription mediated by p65, but not the alternative pathway. HBZ binding to p65 diminished p65's DNA binding capacity and repressed its target genes. HBZ. (Mus musculus) PubMed

 2619.

Expression of HBZ plays a role in pathogenesis of the HTLV-1 associated myelopathy and tropical spastic paraparesis. [HBZ] (Mus musculus) PubMed

 2620.

The authors demonstrate that the repression of c-Jun activity in vivo is mainly due to the HBZ-SP1-mediated sequestration of c-Jun to the HBZ-NBs.[HBZ] (Mus musculus) PubMed

 2621.

p28 function is critical for viral survival in vivo.[p28] (Mus musculus) PubMed

 2622.

data indicate that VP2, a protein apparently unique to the caliciviruses, is essential for productive replication that results in the synthesis and maturation of infectious virions. [VP2] (Mus musculus) PubMed

 2623.

Study reports the crystal and molecular structures of the 3C proteinase and provides insight into the mechanisms underlying the proteolysis of natural substrates by this viral cysteine peptidase. (Mus musculus) PubMed

 2624.

Hepatitis A virus (HAV), a hepatotropic picornavirus, ablates type 1 interferon responses by targeting the 3ABC precursor of its 3C(pro) cysteine protease to mitochondria where it colocalizes with and cleaves MAVS.[3ABC] (Mus musculus) PubMed

 2625.

there seemed to be more mutations in the strains obtained from fulminant hepatitis and acute hepatitis (AH) patients than in those obtained from AH patients in the central part of HAV 2B [HA virus protein 2b] (Mus musculus) PubMed

 2626.

The expression of HAV cellular receptor, cr-1 on CD4 T cells correlated significantly with the antibody responses and cytokine levels.[cr-1] (Mus musculus) PubMed

 2627.

cardioviruses target the same group of nucleoporins as enteroviruses, but the effector mechanism triggered by L (or L-Ran complexes) involves a unique cytosol-dependent phosphorylation cascade rather than proteolysis. (Mus musculus) PubMed

 2628.

L protein is involved in the control of viral antiapoptotic functions. [L protein] (Mus musculus) PubMed

 2629.

RNA-dependent RNA polymerase structure and complex with a template-primer RNA [RNA-dependent RNA polymerase] (Mus musculus) PubMed

 2630.

certain RNA sequences within the foot-and-mouth disease virus (FMDV) 5' untranslated region but outside of the cre/bus can enhance VPg uridylylation activity[VPg] (Mus musculus) PubMed

 2631.

findings suggest that phosphorylation of threonine/serine residues adjacent to the essential RNA-binding site in the auxiliary p33 protein likely plays a role in viral RNA replication and subgenomic RNA synthesis during tombusvirus infections [p33] (Mus musculus) PubMed

 2632.

propose the primary function of reversible phosphorylation of p33 is to regulate RNA binding capacity of p33 which could affect assembly of viral replicase complexes, recruitment of RNA template into replication and/or release RNA from replication [p33] (Mus musculus) PubMed

 2633.

as few as 3 residues of the coat protein R-domain may be sufficient for formation of T=3 particles; between 4 to 13 residues of the R-domain may be required for proper positioning of betaA and beta-annulus structural elements of the C-type subunits [cp] (Mus musculus) PubMed

 2634.

The crystal structure of p21, which reveals an octameric ring architecture with a large central cavity of approximately 90 A diameter, was reported. (Mus musculus) PubMed

 2635.

TGBp1 is an important symptom contributor in PVX infections [TGBp1 protein] (Mus musculus) PubMed

 2636.

A revised model of the three-dimensional organization of coat protein (CP) subunits in the PVX virions is proposed. This two-domain model explains better the high plasticity of the PVX CP structure. [CP] (Mus musculus) PubMed

 2637.

The 25K protein was shown to form homodimers and homooligomers (25K protein). (Mus musculus) PubMed

 2638.

a Nicotiana tabacum kinase of the CK2 family is involved in TBGp1 phosphorylation during the course of viral infection [TGBp1] (Mus musculus) PubMed

 2639.

C-terminal 10/18 amino acids region was not essential for virus-like particle assembly from coat protein, but virus-like particles assembled from the mutant coat protein were incapable of TGBp1 binding and being translationally activated. [TGBp1 and CP] (Mus musculus) PubMed

 2640.

HCPro interferes with some of the catalytic functions of the 20S proteasome suggesting the existence of a novel type of defence and counter-defence interplay in the course of interaction between potyviruses and their hosts.[ HCPro] (Mus musculus) PubMed

 2641.

interactions between the VPg and HcPro of Lettuce mosaic potyvirus (LMV) and between LMV VPg and the lettuce translation initiation factor 4E, the cap-binding protein (eIF4E), were demonstrated in vitro [VPg] (Mus musculus) PubMed

 2642.

This is first report describing two distinct electrophoretic forms corresponding to phosphorylated and dephosphorylated forms of PPV capsid proteins in infected plants. [CP protein] (Mus musculus) PubMed

 2643.

A virus purification protocol demonstrates the Cylindrical Inclusion protein (CI) of PVA is associated with a subpopulation of virions isolated from infected plants. [CI] (Mus musculus) PubMed

 2644.

Five different amino acid substitutions in the VPg of Potato virus Y were shown to be independently responsible for virulence toward pvr2(3) resistance gene of pepper.[VPg] (Mus musculus) PubMed

 2645.

dissociation constants of Tobacco etch virus protease substrate and product peptides using isothermal titration calorimetry for various forms of this enzyme[protease] (Mus musculus) PubMed

 2646.

VPg inhibits cap-dependent translational initiation via binding to eIF(iso)4E [VPg] (Mus musculus) PubMed

 2647.

In cap-bound eIF4E orthologues, the VPg binds to the C-terminal region, which constitutes one side of the entrance to the cap-binding pocket, whereas in cap-free state, VPg binds to the widely opened cap-binding pocket and its surrounding region.[VPg] (Mus musculus) PubMed

 2648.

These results suggest that the viral replication proteins are associated with the intracellular membranes harboring TOM1 and TOM2A and that this association is important for RdRp activity. [TOM1, TOM2A] (Mus musculus) PubMed

 2649.

results show a cis-preferential requirement of p88, but not of p27, for the replication of RNA1.[p88] (Mus musculus) PubMed

 2650.

analysis of lytic activity of flock house virus capsid protein [capsid protein] (Mus musculus) PubMed

 2651.

These data suggest that the packaging of RNA1 is dependent on trafficking of coat protein to mitochondria, the presumed site of FHV assembly, and that this trafficking requires a high density of positive charge in the N terminus. (Mus musculus) PubMed

 2652.

implicate membrane phospholipids as important host determinants for FHV RNA polymerase membrane association [RNA polymerase ] (Mus musculus) PubMed

 2653.

Deletion of a conserved coiled-coil domain from the 2b protein prevented its interaction with CP, whereas deletion of N- and C-terminal domains of the 2b protein greatly enhanced its interaction with CP. [2b protein] (Mus musculus) PubMed

 2654.

Molecular model supports the hypothesis that BMV 1a should have helicase activity (1a replicase). (Mus musculus) PubMed

 2655.

A highly conserved cis-acting 3' tRNA-like structure is required for the packaging of B3 in vivo, but not for B1 or B2. [B3, B2, & B1] (Mus musculus) PubMed

 2656.

study tested the assumption that phosphorylation may be a mechanism that regulates B3a movement protein functions and showed that not only B3a but also the coat protein, BCP, was phosphorylated in BMV-infected barley protoplasts. [B3a, BCP] (Mus musculus) PubMed

 2657.

we have created partial protein models for the region surrounding residue 461 of 1a protein which can account structurally for the effect of aa 461 on elicitor function in the hypersensitive response [1a protein] (Mus musculus) PubMed

 2658.

These results suggest that Tcoi1 controls the propagation of CMV through an interaction with the CMV 1a protein.[Cucumber mosaic virus 1a protein] (Mus musculus) PubMed

 2659.

The results indicate that TGB2 and gammab proteins play a previously unknown functional role at the site of virus replication.[triple-gen block 2 protein] (Mus musculus) PubMed

 2660.

These experiments suggest that BSMV movement requires physical interactions of TGB2 and TGB3 and that substantial deviation from the TGB protein ratios expressed by the wild-type virus compromises movement.[TGB2 and TGB3] (Mus musculus) PubMed

 2661.

the ORF3 protein exploits the endosomal sorting machinery to enhance the secretion of an immunosuppressant molecule (alpha1 microglobulin) from cultured hepatocytes [ORF3] (Mus musculus) PubMed

 2662.

when expressed through baculovirus, the ORF1 polyprotein was processed into smaller proteins that correlated with their proposed functional domains; this processing mainly depended upon a cysteine protease [ORF1] (Mus musculus) PubMed

 2663.

in contrast to its requirement in vivo, ORF3 protein is not required for infection of Huh-7 cells or production of infectious virus in vitro (ORF3 protein) (Mus musculus) PubMed

 2664.

defines the pathway by which ORF2 obtains access to the cytoplasm[ORF2 protein] (Mus musculus) PubMed

 2665.

hepatitis E virus Orf3 protein protects cells from mitochondrial depolarization and death [Orf3] (Mus musculus) PubMed

 2666.

A potential oral vaccine is provided by virus-like particles formed by a protein construct of partial ORF3 protein (residue 70-123) fused to the N-terminus of the ORF2 protein (residues 112-608). (hepatitis E virus ORF3 and ORF2 proteins) (Mus musculus) PubMed

 2667.

The authors propose that through its effects on EGFR trafficking, pORF3 prolongs endomembrane growth factor signaling and promotes cell survival. The effects on STAT3 translocation would result in a reduced inflammatory response. (Mus musculus) PubMed

 2668.

ORF3 protein, at least its C-terminal portion, is present on the surface of HEV virions released from infected cells. [ORF3] (Mus musculus) PubMed

 2669.

The ORF3-fibrinogen Bbeta interaction was verified by co-immunoprecipitation and fluorescence resonance energy transfer in mammalian cells. (Mus musculus) PubMed

 2670.

These results suggest that the ORF3 protein is responsible for virion egress from infected cells and is present on the surface of released hepatitis E virus particles, which may be associated with lipids.[Orf3] (Mus musculus) PubMed

 2671.

HEV ORF3 product localizes to microtubules and interferes with their dynamics. vp13 led to elevation of acetylated alpha-tubulin. [vp13] (Mus musculus) PubMed

 2672.

The results showed that HIF-1alpha, a highly unstable subunit of the HIF-1, was stabilized in hepatitis E virus ORF3-expressing cells.[ORF3] (Mus musculus) PubMed

 2673.

we report for the first time the crystal structure of the HEV capsid protein domain E2s (Mus musculus) PubMed

 2674.

Endoplasmic reticulum stress and nfkb activation initiates the signal for inducing Hepatitis D LDAg translocation to cytoplasm by Hepatitis b virus surface antigens [LDag] (Mus musculus) PubMed

 2675.

data suggest that a protonated base triple allows the WT ribozyme to maintain appreciable activity at acidic pH, which could play an important role in the life cycle of the virus[HDV ribozyme] (Mus musculus) PubMed

 2676.

Comparison of a systematic set of cis- and trans-acting HDV ribozymes shows that the absence of either L4 or J1/2 significantly and independently impacts catalytic activity [ribozyme] (Mus musculus) PubMed

 2677.

the structure of native JcDNV at 8.7A resolution and of the two VLPs formed essentially from VP2 and VP4 at 17 A resolution, as determined by cryo-electron microscopy [VP2 & VP4] (Mus musculus) PubMed

 2678.

sequence critical for P9-driven expression identified within the overlapping 3' coding region of the viral capsid protein and non-structural genes [P9] (Mus musculus) PubMed

 2679.

This study demonstrates the significance of VP2 in CAV replication and shows that specific mutations introduced into the gene encoding this protein can reduce virus replication, cytopathogenicity and downregulation of MHC I in infected cells. [VP2] (Mus musculus) PubMed

 2680.

describes the substrate preferences and determinants of specificity for the dengue virus NS2B(H)-NS3pro protease [NS3, dengue virus] (Mus musculus) PubMed

 2681.

the neutralizing epitopes of the DENV-2 Domain III to its specific neutralization antibody (mAb 137-22) by site-directed mutagenesis (Mus musculus) PubMed

 2682.

envelope protein fusion peptide - mutation impairs fusion efficiency and reduces virus reactivity with flavivirus group-reactive antibodies (Mus musculus) PubMed

 2683.

Core protein major features are a human HBV core protein-like two-domain structure with an assembly domain comprising the first about 185 amino acids and a C-terminal nucleic acid binding domain, connected by a morphogenic linker region.[core protein] (Mus musculus) PubMed

 2684.

The inhibitory effect of DHBe on infection could play a role in maintaining viral persistence. [E antigen] (Mus musculus) PubMed

 2685.

These findings identify E163 as a new chemokine binding protein in poxviruses and provide a molecular mechanism for the immunomodulatory activity previously reported for the vaccinia virus A41 ortholog.[E163] (Mus musculus) PubMed

 2686.

The type I interferon (IFN) binding protein (bp) of ECTV, is essential for ECTV virulence and is a natural target of the antibody response.[type I IFN binding protein] (Mus musculus) PubMed

 2687.

Data show that ectromelia virus CD30 is expressed as a secreted disulfide linked trimer and that the absence of vCD30 does not impair mousepox induced fatality in vivo [CD30]. (Mus musculus) PubMed

 2688.

The M2-2 protein expressed at a high level completely inhibited respiratory syncytial virus replication. (M2-2 protein) (Mus musculus) PubMed

 2689.

this paper shows that Fbl is a fibrinogen-binding adhesin and a clumping factor [Fbl] (Mus musculus) PubMed

 2690.

AtlL is the first autolysin described in S. lugdunensis, with a bifunctional enzymatic (N-acetylglucosaminidase and N-acetylmuramoyl-l-alanine amidase activities) in peptidoglyan hydrolysis. [AtlL] (Mus musculus) PubMed

 2691.

study suggests that 2b in PRRSV is similar to the E protein in equine arteritis virus and forms a minor structural component of the virion [2b protein] (Mus musculus) PubMed

 2692.

Results report the crystal structure of nsp1alpha of PRRSV, and suggest that it functions differently from other reported viral leader proteases, such as that of foot-and-mouth disease [Nsp1alpha]. (Mus musculus) PubMed

 2693.

The triple gene block protein 1 (TGBp1) encoded by Plantago asiatica mosaic virus (PlAMV), exhibited a strong suppressor activity, on the accumulation of microRNA, virus genomic RNA and virus-derived small interfering RNAs. [TGBp1] (Mus musculus) PubMed

 2694.

v-slfn is an orthopoxvirus virulence factor that affects the host immune response to infection.[v-slfn] (Mus musculus) PubMed

 2695.

SseF interacts functionally and physically with SseG but not SifA and is also required for the perinuclear localization of Salmonella vacuoles. (SseF)(SseG) (Mus musculus) PubMed

 2696.

O-antigen contains repeating unit of ribitol phosphate and 2-acetimidoylamino-2,6-dideoxy-L-galactose. [O-antigen] (Mus musculus) PubMed

 2697.

a functional role to the Salmonella effector SlrP as a binding partner and an E3 ubiquitin ligase for mammalian thioredoxin [SlrP] (Mus musculus) PubMed

 2698.

induced within macrophages by phagosome acidification; may play a role in the establishment of the intracellular replication niche [virulence factor A; bvfA] (Mus musculus) PubMed

 2699.

these results suggest that Brucella T4SS VirB is not involved in the control of dendritic cells maturation and does not interfere with the establishment of a T-helper type 1 adaptive immune response.[VirB in strain ATCC 23444] (Mus musculus) PubMed

 2700.

Small-angle X-ray scattering analysis of Rhodothermus marinus Cel12A showed that the enzyme forms a loosely associated antiparallel dimer in solution, which may target the enzyme to the antiparallel polymer strands in cellulose [Cel12A] (Mus musculus) PubMed

 2701.

Single-subunit Na+/H+ antiporter NhaE from Rhodothermus marinus nqoB operon of complex I is functional regarding sodium translocation, except at alkaline pH. (NhaE) (Mus musculus) PubMed

 2702.

Data show that the contribution of the trehalose transporter is important only in trehalose-poor environments, and that at higher concentrations trehalose is assimilated primarily via trehalase and the glucose transport system [trehalase] (Mus musculus) PubMed

 2703.

X-ray diffraction data for a cytochrome c were collected to 1.23 A resolution using synchrotron radiation and a wavelength of 0.93 A. [14kDa cyt c] (Mus musculus) PubMed

 2704.

Thermophilic endo-1,3(4)-beta glucanase (laminarinase) from Rhodothermus marinus was crystallized.[endo-1,3(4)-beta glucanase] (Mus musculus) PubMed

 2705.

shared activity of HPV-16 E7 and HPV-6 E7 to destabilize p130 and decrease or delay differentiation may be related to the role of E7 in the HPV life cycle [E7 protein] (Mus musculus) PubMed

 2706.

The E2-DNA complex results in considerable bending of the DNA, which is facilitated by sequences with A:T-rich spacers that adopt a pre-bent conformation (E2 protein). (Mus musculus) PubMed

 2707.

analysis of complex formation and catalytic activation by the PII signaling protein of N-acetyl-L-glutamate kinase from Synechococcus elongatus strain PCC 7942 [PII signaling protein] (Mus musculus) PubMed

 2708.

For nitrate reductase complementary spectroscopic studies suggest a structural context for the activation[nitrate reductase ] (Mus musculus) PubMed

 2709.

The proposed binding mode of KaiB explains the observation of simultaneous binding of KaiA and KaiB to KaiC, and provides insight into the mechanism of KaiB's antagonism of KaiA.[KaiB, KaiC] (Mus musculus) PubMed

 2710.

RpaB interacts with a high light regulatory 1 element of several high light-responsive promoters. Under normal light conditions RpaB functions as a repressor, but its activity is weakened during high light stress. [RpaB] (Mus musculus) PubMed

 2711.

The C-terminal loops of KaiC, the "A-loops", are the master switch that determines overall KaiC activity.[KaiC] (Mus musculus) PubMed

 2712.

high-resolution structures of KaiA, KaiB, and KaiC suggest a ratcheting mechanism by which the KaiABC oscillator ticks unidirectionally[review][KaiA,KaiB, KaiC] (Mus musculus) PubMed

 2713.

Data show that the non-conserved C-terminus of Synechococcus elongatus N-acetylglutamate kinase (NAGK) enhances arginine inhibition and holds most of the differences between S. elongatus and Arabidopsis NAGK with respect to arginine sensitivity [NAGK]. (Mus musculus) PubMed

 2714.

morphological and behavioral differences in septin rings require the Elm1p and Gin4p kinases.[Elm1, Gin4] (Mus musculus) PubMed

 2715.

Murine gammaherpesvirus 68 (gammaHV68) v-cyclin and v-bcl-2 genes are required for the efficient induction of gammaHV68-associated atypical lymphoid hyperplasia in BALB beta(2)m(-/-) mice. [v-Bcl-2] (Mus musculus) PubMed

 2716.

Our results for MHV-68 ORF64, ubiquitin-specific protease (USP), are consistent with an enzymatic function of the tegument protein that is beneficial to the virus during acute infection, particularly in vivo. [USP] (Mus musculus) PubMed

 2717.

The SVV immediate-early gene 62 (IE62) product transactivates ORF 28 and 29 expression, and a cellular upstream stimulatory factor-binding site is important for efficient IE62 induction of genes 28 and 29. [ORF 29 (Dna-binding protein), IE62] (Mus musculus) PubMed

 2718.

These findings indicate that the defective presentation of class I MHC antigen on hepatocytes transcribing WHV is a consequence of posttranscriptional suppression exerted by virus pre-S2 protein and can be fully reversed by IFN-gamma. [Pre-S2 protein] (Mus musculus) PubMed

 2719.

One interpretation of these data is that host range specificity of HDV is determined entirely by pre-S1 and that the woodchuck hepatitis virus and Hepatitis B virus pre-S1 proteins recognize different receptors on primary human hepatocytes. (Mus musculus) PubMed

 2720.

Mutation analysis of the helicase-like domain of BaMV replicase possessing RNA 5'-triphosphatase and NTPase activities suggests that the activities are required for BaMV survival. [RNA 5'triphsophatase/NTPase] (Mus musculus) PubMed

 2721.

These results raise the possibility that TGBp2 facilitates intracellular delivery of viral RNA through non-specific protein-RNA interaction.[TGBp2] (Mus musculus) PubMed

 2722.

N-terminal region of NSm, which includes domain I and part of domain II, is required for virus assembly and the C-terminal hydrophobic domain V may function as an internal signal sequence for the Gc glycoprotein. (Mus musculus) PubMed

 2723.

Receptor Binding Protein structure of the temperate phage TP901-1 [RBP] (Mus musculus) PubMed

 2724.

the expression of pilA, which encodes the pilistructural protein, is directly regulated by a two-component regulatory system in which PilR functions as an RpoN-dependent enhancer binding protein [PilR] (Mus musculus) PubMed

 2725.

MacA is not directly involved in electron transfer to Fe(III). [MacA] (Mus musculus) PubMed

 2726.

structure solved by Fe SAD using data collected to a resolution of 1.86 A. In crystal, packing interactions in 1 dimension were exclusively mediated through Strep-tag II sequence. Tag & linker regions were in contact with 3 further monomers of OmcF[OmcF] (Mus musculus) PubMed

 2727.

Outer membrane cytochrome c, OmcF, from Geobacter sulfurreducens shows high structural similarity to an algal cytochrome c6.[OmcF] (Mus musculus) PubMed

 2728.

structural and biochemical characterization of the globin domain of the globin coupled sensors from Geobacter sulfurreducens (GsGCS(162)) is reported (Mus musculus) PubMed

 2729.

Data suggest that the new type multihaem cytochroms are formed with domains homologous to the trihaem cytochrome c7: [cytochrome c7] (Mus musculus) PubMed

 2730.

data show that CcpA variants S134P/V135K and S134P led to a distortion of the loop region, accompanied by an opening of the active-site loop, leaving the enzyme in a constitutively active state [Ccpa] (Mus musculus) PubMed

 2731.

1.6 A crystal structure of a KinI motor core; results of this study confirm the suspected importance of loop 2 for KinI function, and provide evidence that KinI is specialized to hydrolyze ATP after initiating depolymerization [KinI] (Mus musculus) PubMed

 2732.

Vps4 mediates multivesicular body formation [Vps4] (Mus musculus) PubMed

 2733.

PSAC is a target for antimalarial development. (plasmodial surface anion channel) (Mus musculus) PubMed

 2734.

PFB0150. Putative Ser-Thre kinase. AA 26-55 bind to band protein 4.1. (Mus musculus) PubMed

 2735.

Data suggest that calcium-dependent protein kinase 1 belongs to a novel class of proteins whose export is dependent on a 'non-classical' pathway involving N-myristoylation/palmitoylation [cdpk1] (Mus musculus) PubMed

 2736.

cloning and expression analysis of dihydroorotase, orotate phosphoribosyltransferase, and OMP decarboxylase (Orotidine Phosphate Carboxy-Lyase, also called OMP Decarboxylase) (Mus musculus) PubMed

 2737.

P. falciparum expresses the proteins Pdx1 and Pdx2, corresponding to the yeast enzymes Snz1-p and Sno1-p, which are essential for the vitamin B6 biosynthesis [pdx2] (Mus musculus) PubMed

 2738.

A nested polymerase chain reaction (PCR) using allele-specific primers for merozoite surface protein-2 gene was used to determine the parasite diversity of Plasmodium falciparum causing cerebral malaria. [msp-2] (Mus musculus) PubMed

 2739.

analysis of Plasmodium falciparum cytoadherence-linked asexual protein 3 (CLAG 3) sequences that specifically bind to C32 cells and erythrocytes [CLAG3] (Mus musculus) PubMed

 2740.

identified two genes, H101 and H103, related to MSP3; H101 and H103 are expressed during the asexual cycle and immunofluorescence indicates H103 localises to the merozoite surface as a peripheral membrane protein[H101, H103] (Mus musculus) PubMed

 2741.

var2CSA is transcriptionally up-regulated in CSA-binding parasites; CSA-binding domains in var2CSA defined [var2CSA] (Mus musculus) PubMed

 2742.

identification of a second copy of the small subunit gene, termed PfR4, encoding a 324 amino acid residue polypeptide that shares only 25% identity with the previously identified PfR2 small subunit of Plasmodium falciparum [PfR2 and PfR4] (Mus musculus) PubMed

 2743.

detection of translation of the tufA gene encoded by the Plasmodium falciparum apicoplast genome [tufA] (Mus musculus) PubMed

 2744.

High prevalence of Plasmodium falciparum pfcrt K76T mutation in pregnant women taking chloroquine prophylaxis in Senegal. [pfcrt] (Mus musculus) PubMed

 2745.

enzyme activation of hypoxanthine guanine phosphoribosyltransferase is effected by the product, inosine monophosphate (IMP), and not by the substrates [HGPRT] (Mus musculus) PubMed

 2746.

identified and characterized an immunophilin of the FKBP family, FKBP35; it's an essential parasitic chaperone with a novel drug-independent calcineurin-inhibitory activity [FKBP35] (Mus musculus) PubMed

 2747.

hemoperoxidase has a role in P. falciparum growth, as shown when its inhibition by clotrimazole leads to oxidative stress (Mus musculus) PubMed

 2748.

analysis of TBP-TFIIB complex structure from Plasmodium falciparum [TBP] (Mus musculus) PubMed

 2749.

NIMA-related kinase NEK-4 plays an essential role in zygote-to-ookinete transformation by regulating the DNA replication that precedes meiosis. {NEK-4; NIMA-related protein kinase 4) (Mus musculus) PubMed

 2750.

Plasmodium falciparum chloroquine resistance transporter (pfcrt) is involved in carrier-mediated chloroquine efflux from resistant cells. (Plasmodium falciparum chloroquine resistance transporter; pfcrt) (Mus musculus) PubMed

 2751.

The molecular characterization of a novel cyclic nucleotide PDE (phosphodiesterase), isolated from the human malaria parasite P. falciparum and designated PfPDE1.[PfPDE1] (Mus musculus) PubMed

 2752.

comparison of two structures, one with an empty nucleoside-binding site and a sulfate ion bound in the phosphate-binding pocket and one with substrate inosine bound reveals changes in the active site upon ligand binding (purine nucleoside phosphorylase) (Mus musculus) PubMed

 2753.

upregulation of PfRH4 expression in the subclone Dd2(NM) suggests its role in erythrocyte invasion through the sialic acid independent pathway of Dd2(NM)[RH4] (Mus musculus) PubMed

 2754.

structure of ribose 5-phosphate isomerase has been determined by molecular replacement at 2.09 angstroms resolution [ribose 5-phosphate isomerase] (Mus musculus) PubMed

 2755.

biosynthesis of GAP45 and identify acylation by both myristoylation and palmitoylation as potentially important modifications of this protein [GAP45] (Mus musculus) PubMed

 2756.

PfPKB is a protein kinase B-like enzyme from Plasmodium falciparum (Mus musculus) PubMed

 2757.

The morphologies of erythrocytic falcipain-1 and falcipain-2' knockout parasites were indistinguishable from those of wild-type parasites. [falcipain-1, falcipain-2'] (Mus musculus) PubMed

 2758.

Plasmodium falciparum chloroquine resistance marker protein (Pfcrmp) may be a chlroquine target protein in nucleus and that chloroquine resistance in malaria parasites may be caused by genetic alterations in Pfcrmp gene. [Pfrcmp] (Mus musculus) PubMed

 2759.

provide solid evidence for the uptake of diverse solutes via plasmodial surface anion channel and implicate one or more parasite genes in expression of this channel[ plasmodial surface anion channel ] (Mus musculus) PubMed

 2760.

Parasites with MSP-1(19) haplotypes different from that of the leading vaccine strain were consistently the most prevalent at a vaccine trial site. (Mus musculus) PubMed

 2761.

Dead-box helicase 60kda in size shows ATP and Mg2+ dependent DNA unwinding, ssDNA-dependent ATPase and ATP-binding activities at wide ph and is schizont stage specific. [PfDH60] (Mus musculus) PubMed

 2762.

Helicase 45 is an indispensable enzyme that is essential for growth, and probably survival, of P. falciparum (helicase 45). (Mus musculus) PubMed

 2763.

These studies demonstrate the characterization of the catalytic subunit of signal peptidase complexSPC from P. falciparum. [SP21] (Mus musculus) PubMed

 2764.

Cargo-binding function of Sec24 is conserved and that accumulation of cargo in discrete endoplasmic reticulum sites depends upon positive sorting signals. [Sec24] (Mus musculus) PubMed

 2765.

The parasites successively and spontaneously switched to transcribe a shared var-gene (var2csa) matched by the loss of PfEMP1 surface expression and host cell-binding.[var2csa] (Mus musculus) PubMed

 2766.

Upon ligand binding, several conformational changes occur in PfFKBD, including aromatic residues that shape the FK506 binding pocket as shown by NMR studies (Mus musculus) PubMed

 2767.

ring exported protein 1 targeting to the Maurer's clefts is mediated by a two-phase process [REX1] (Mus musculus) PubMed

 2768.

Study shows that the merozoite-acquired RhopH complex (comprising RhopH1, RhopH2, and RhopH3)is transferred to defined domains of the red blood cell cytoplasm, and possibly transiently associated with Maurer's clefts.[RhopH1, RhopH2, RhopH3] (Mus musculus) PubMed

 2769.

ORC5 forms distinct nuclear foci colocalized with the PCNA and co-immunoprecipitates with PCNA during early-to-mid trophozoite stage replicating parasites. [ORC5] (Mus musculus) PubMed

 2770.

These studies reveal the importance of the REX1 protein in determining the ultrastructure of the Maurer's cleft system. (Mus musculus) PubMed

 2771.

These data implicate an important role for SERA5 in the regulation of the intraerythrocytic development of late-stage parasites and as a target for drug development.[SERA5] (Mus musculus) PubMed

 2772.

two substrates of Plasmodium falciparum CDPK1: myosin A tail domain-interacting protein (MTIP) and glideosome-associated protein 45 (GAP45), both of which are components of the motor complex (Mus musculus) PubMed

 2773.

RON2 forms a complex with AMA1 in Plasmodium falciparum merozoites, indicative of a fundamental role in host cell invasion. forms a complex with AMA1 in Pf merozoites. (Mus musculus) PubMed

 2774.

The distribution of the 130 kDa Maurer's cleft protein changes from within the parasite to the clefts during intracellular RBC development as the parasite matures from young trophozoite to segmented schizont. [130kda Maurer's cleft protein] (Mus musculus) PubMed

 2775.

The biochemical characterization and elucidation of molecular mechanisms involved in the regulation of PfCDPK4, is reported.[PfCDPK4] (Mus musculus) PubMed

 2776.

Purified immunoglobulin G raised in rabbits against the binding domain of PfRh4 blocked the binding of native PfRh4 to the surfaces of erythrocytes and inhibited erythrocyte invasion. (Mus musculus) PubMed

 2777.

The plasmodial surface anion channel may be encoded by multiple parasite genes and has a Complex inheritance pattern. [PSAC] (Mus musculus) PubMed

 2778.

Results describe the mechanism of the metal dependency of arginase by means of homology modelling and molecular dynamics [arginase]. (Mus musculus) PubMed

 2779.

Der1-1 and Uba1 (homologues of yeast ERAD components) localize to the apicoplast. [Uba1] (Mus musculus) PubMed

 2780.

Longin domain is required for both endoplasmic reticulum and Golgi apparatus recycling of Sec22. [Sec22] (Mus musculus) PubMed

 2781.

zfPDYN cDNA codes for a polypeptide of 252 amino acids that contains the consensus sequences for four opioid peptides: an Ile-enkephalin, the neo-endorphins, dynorphin A and dynorphin B. (Mus musculus) PubMed

 2782.

the transient expression of purpurin protein was greatly different during development and optic nerve regeneration. (Mus musculus) PubMed

 2783.

the Asian strain viral precursor protein E3E2 is cleaved most efficiently by furin and PC5A. This cleavage was also observed in CHIKV-infected cells and could be blocked by furin inhibitor decanoyl-RVKR-chloromethyl ketone [E2 surface glycoprotein] (Mus musculus) PubMed

 2784.

may induce gp130 signaling by an exclusively autocrine mechanism that relies on intracellular binding to its receptor (interleukin-6) (Mus musculus) PubMed

 2785.

role in the segregation of equivalent amounts of viral genomes tethered with LANA into two daughter progeny cells during cell division [LANA(latency associated nuclear antigen)] (Mus musculus) PubMed

 2786.

ORF57 and hnRNP K interaction may modulate ORF57-mediated regulation of viral gene expression [ORF57] (Mus musculus) PubMed

 2787.

LANA expression protects lymphoid cells from p16 INK4a-induced cell cycle arrest and induces S-phase entry.[LANA] (Mus musculus) PubMed

 2788.

role for the inverted repeat in LANA1 binding to KSHV DNA [LANA1 (latency- associated nuclear antigen 1)] (Mus musculus) PubMed

 2789.

a latent KSHV gene product, kaposin B, increases the expression of cytokines by blocking the degradation of their messenger RNAs [kaposin B] (Mus musculus) PubMed

 2790.

study demonstrates that LANA physically associates with RBP-Jkappa in vitro and in KSHV-infected cells, with the complex formed capable of binding to RBP-Jkappa cognate sequences [LANA] [RBP-Jkappa] (Mus musculus) PubMed

 2791.

DNase and host shutoff activities of SOX are genetically separable. [SOX protein] (Mus musculus) PubMed

 2792.

findings demonstrate that the proposed leucine zipper region of K-bZIP (amino acids 182 to 218) is required for multimer formation but that it does not fold as a coiled coil[K-bZIP protein] (Mus musculus) PubMed

 2793.

findings showed that MIR1 promoted down-regulation of HLA-B7 molecules lacking lysine residues in their intracytoplasmic domain [MIR1] (Mus musculus) PubMed

 2794.

These data indicate that vFLIP uses TRAF2 and TRAF3 for signalling to NF-kappaB, which is crucial for KSHV-associated lymphomagenesis [vFLIP] (Mus musculus) PubMed

 2795.

Kaposi's sarcoma-associated herpesvirus complement control protein (KCP) binds to heparin at physiological ionic strength. (KCP) (Mus musculus) PubMed

 2796.

findings show that N-terminal LANA docks onto chromosomes by binding nucleosomes through the folded region of histones H2A-H2B (Mus musculus) PubMed

 2797.

vIRF-2 protein is an interferon induction antagonist that acts pleiotropically, presumably facilitating KSHV infection and dissemination in vivo. [IRF-2] (Mus musculus) PubMed

 2798.

Promoter switching allows simultaneous transcription of LANA and K14/vGPCR [LANA] (Mus musculus) PubMed

 2799.

The acidic-repeat region of LANA-1 could function as an in cis-acting inhibitor of antigen presentation, which may contribute to the immune evasion of cells latently infected by KSHV. (Mus musculus) PubMed

 2800.

three NLSs identified in ORF57 provide at least two functions, nuclear localization of ORF57 and up-regulation of ORF59 expression.(ORF57) (Mus musculus) PubMed

 2801.

The latency-associated nuclear antigen (LANA) directly associated with a low oxygen responder, hypoxia-inducible factor-1 alpha (HIF-1 alpha). (LANA) (Mus musculus) PubMed

 2802.

UNG2 binds to the carboxyl terminus of LANA and retains its enzymatic activity in the complex.[LANA] (Mus musculus) PubMed

 2803.

gpK8.1 interaction with human fibroblasts induces antiviral response, as characterized by the activation of interferon regulatory factor 3 (IRF-3), production of interferon beta (IFN-beta), and expression of interferon-stimulated antiviral genes.[gpK8.1] (Mus musculus) PubMed

 2804.

LANA associated with repressed cellular promoters, recruited Dnmt3a to DNA, and facilitated de novo promoter methylation of a down-regulated gene, cadherin 13 (H-cadherin). [LANA] (Mus musculus) PubMed

 2805.

Hx8 appears to exert a key role in receptor stabilization through the conserved residue R7.61, directing the ligand binding profile of ORF74 and likely also that of other class A G-protein-coupled receptors [ORF74] (Mus musculus) PubMed

 2806.

For virus replication to take over Kaposi sarcoma cell and produce lytic infection requires that viral gene expression of ORF57 outpace that of the host cell. [KSHV ORF57 (open reading frame 57)] (Mus musculus) PubMed

 2807.

the KRAB-containing zinc finger protein K-RBP can suppress RTA-mediated transactivation and KSHV lytic replication and KSHV utilizes this protein as a regulator to maintain a balance between latency and lytic replication [K-RBP] (Mus musculus) PubMed

 2808.

Results show that the LANA1 QED-rich central repeat (CR) region, particularly the CR2CR3 subdomain, retards LANA1 synthesis and markedly enhances LANA1 stability in vitro and in vivo, similar to the Epstein-Barr virus nuclear antigen-1 [LANA1] (Mus musculus) PubMed

 2809.

We also show that RTA regulates ORF59 promoter through interaction with RBP-Jkappa as well as a cis-acting RTA responsive element within the promoter. [ORF59] (Mus musculus) PubMed

 2810.

latency-associated nuclear antigen itself was localized mainly to the nuclear matrix fraction but also that TR region of the KSHV genome existed together in the G1 phase [latency-associated nuclear antigen ] (Mus musculus) PubMed

 2811.

Late tumour stages of Kaposi sarcoma in tissues from HIV-positive patients are associated with high levels of LANA-1, HIF-1alpha and of the anti-apoptotic proteins, Bcl-2 and Mcl-1 [LANA-1]. (Mus musculus) PubMed

 2812.

GBV-B has an analogous p7 protein to HCV p7 [p7 protein] (Mus musculus) PubMed

 2813.

The characterization of the targeting and insertion of p36 into the mitochondrial outer membrane also sheds light on the mechanisms involved in sorting of host-cell membrane proteins to mitochondria. (Mus musculus) PubMed

 2814.

Rv-cyclin down regulates NF-kappaB-dependent transcription, whether induced by TNFalpha or by direct phosphorylation of IkappaB by expressed MEKK1.[rv-cyclin] (Mus musculus) PubMed

 2815.

Duplicate open reading frames ( Rf-1A and Rf-1B) with a pentatricopeptide (PPR) motif were cloned; it is concluded that Rf-1A is the Rf-1 gene [Rf-1A] (Mus musculus) PubMed

 2816.

OsCRL4 represents a new member of the cytokinin receptor protein in rice. [CRL4] (Mus musculus) PubMed

 2817.

upregulation of OsSBP expression conferred enhanced tolerance to different pathogens, possibly by increasing plant sensitivity to endogenous defense responses [OsSBP] (Mus musculus) PubMed

 2818.

differential expression of SIG genes in leaf morphogenesis, suggesting the existence of tissue- and stage-specific functions of SIG proteins for transcriptional regulation of chloroplast genes in plant development [SIG1], [SIG2A] (Mus musculus) PubMed

 2819.

Genes catalyze sequential cyclization steps in momilactone diterpenoid biosynthesis and seem to have been evolutionarily coupled by physical linkage and resulting cosegregation. [OsDTS2] (Mus musculus) PubMed

 2820.

The gene for OsMADS18 protein is expressed in rice (OsMADS18), overinduction leading to early flowering.[OsMADS18] (Mus musculus) PubMed

 2821.

Telomerase reverse transcriptase (OsTERT) contains at least five alternatively spliced transcripts and two putative phosphorylation sites for Akt kinase [OsTERT] (Mus musculus) PubMed

 2822.

OsENT2 mediates adenosine transport, but has brooad substrate specificity (equilibrative nucleoside transporter 2) (Mus musculus) PubMed

 2823.

results indicate that OsGNA1 is required for maintaining normal root cell metabolism and cell shape [glucosamine-6-P acetyltransferase, OsGNA1] (Mus musculus) PubMed

 2824.

Al-resistant seedlings and Al-sensitive seedlings segregated at a 3 : 1 ratio, indicating that the high sensitivity to Al in als1 is controlled by a single recessive gene. The gene was mapped to the long arm of chromosome 6. [als1] (Mus musculus) PubMed

 2825.

The mutant of rice (Oryza sativa L. ssp. indica cv IR8) arm2 is defective in the uptake of the naturally occurring auxin indole-3-butyric acid (IBA) [ARM2] (Mus musculus) PubMed

 2826.

The pms3 (a gene for photoperiod-sensitive genic male sterility) locus was assigned to a 28.4-kb DNA fragment by chromosome 12 genetic and physical mapping. (Mus musculus) PubMed

 2827.

The upregulation of RERJ1 in response to wounding and water stress is reported. [RERJ1] (Mus musculus) PubMed

 2828.

The effects of overexpression as well as insertional mutagenesis of the rice two-pore channel 1 (OsTPC1), a putative voltage-gated Ca(2+)-permeable channel, on a proteinaceous fungal elicitor-induced defense responses in rice cells is reported. [TPC1] (Mus musculus) PubMed

 2829.

Spontaneously occurring mutations in the CPD photolyase gene cause different degrees of sensitivity to UVB in rice. (Mus musculus) PubMed

 2830.

data suggest that OsSERK1 may partially mediate defense signal transduction in addition to its basic role in somatic embryogenesis [SERK1] (Mus musculus) PubMed

 2831.

cloning of the R gene Xa27 from rice and the cognate avr gene avrXa27 from Xanthomonas oryzae pv. oryzae [Xa27] (Mus musculus) PubMed

 2832.

Possible functions of the GYM (gypsy embryo) gene and the ovule developmental mechanism are discussed.[GYM] (Mus musculus) PubMed

 2833.

The htd-1 mutant increases its tiller number by releasing axillary buds from dormant stage rather than by initiating more axillary buds. By map-based cloning, the htd1 gene was fine mapped in a 30-kb DNA region on chromosome 4 (htd1). (Mus musculus) PubMed

 2834.

The OsBIHD1 protein may be positively involved in activating expression of the defence-related genes in disease resistance responses, and is also important in rice development and abiotic stress tolerance. (Mus musculus) PubMed

 2835.

The isolation and characterization of 4 DCL proteins in O. sativa is reported. [DCL1; DCL2; DCL3; DCL4] (Mus musculus) PubMed

 2836.

Pi36(t) is a novel rice blast resistance gene located on rice chromosome 8 [Pi36(t)] (Mus musculus) PubMed

 2837.

SKC1 is involved in regulating K(+)/Na(+) homeostasis under salt stress. (SKC1) (Mus musculus) PubMed

 2838.

OsBIHD1 is a BELL type of homeodomain transcription factor present in the nucleus, whose induction is associated with resistance response in rice.[BIHD1] (Mus musculus) PubMed

 2839.

DBS1 encodes a NACK-type kinesin-like protein (OsNACK); dbs1 mutation causes a severe defect in DBS1 function but does not completely shut it down. [dbs1] (Mus musculus) PubMed

 2840.

isolated a putative transcription factor designated OsCBT; results suggest that OsCBT is a transcription activator modulated by calmodulin [CBT] (Mus musculus) PubMed

 2841.

GID1 is a soluble receptor mediating gibberellin signalling in rice [GIBBERELLIN INSENSITIVE DWARF1 = GID1] (Mus musculus) PubMed

 2842.

proposed that OsGAP1 facilitates vesicular trafficking from the trans-Golgi network to the plasma membrane or central vacuole by both stimulating the GTPase activity of OsRab11 and increasing the recycling of inactive OsRab11 [GAP1] (Mus musculus) PubMed

 2843.

OsZIP4 is a Zn transporter that may be responsible for the translocation of Zn within rice plants. (Mus musculus) PubMed

 2844.

A defect in the cytosolic AGPase small subunit2b transcription from the AGPS2 gene in endosperm sharply enhanced the expressions of endosperm and leaf plastidial AGPS1, the endosperm cytosolic AGPase large subunit2 (AGPL2), and the leaf plastidial AGPL1. (Mus musculus) PubMed

 2845.

These data suggest that the RMtATP6 protein acts as a subunit of ATP synthase, and is expressed in response to stress from several salts [RMtATP6]. (Mus musculus) PubMed

 2846.

Sequence comparison analysis reveals that the six paralogs at the Pi9 locus belong to four classes and gene duplication took place to form the gene cluster. Nbs2-Pi9 is the Pi9 gene. (Pi9) (Mus musculus) PubMed

 2847.

a single recessive gene, tentatively designated as bph19(t), conditioned the resistance against brown planthopper.The bph19(t) locus was physically defined to an interval of about 60 kb.[BPH19] (Mus musculus) PubMed

 2848.

The identification of Elongated Uppermost Internode (Eui) as a gibberellins (GAs) catabolism gene provides additional evidence that the GA metabolism pathway is a useful target for increasing the agronomic value of crops (Mus musculus) PubMed

 2849.

Phylogenetic analysis, supported by comparative mapping in rice and maize (Zea mays), showed that Rc, a positive regulator of proanthocyanidin, is orthologous with INTENSIFIER1, a negative regulator of anthocyanin production in maize. (Mus musculus) PubMed

 2850.

GID1 functions as a GA receptor. [GID1] [GIBBERELLIN INSENSITIVE DWARF1] (Mus musculus) PubMed

 2851.

PLASTOCHRON2 acts to retard the rate of leaf maturation and is revealed to be an orthologue of terminal ear1, a maize (Zea mays) gene that encodes a MEI2-like RNA binding protein. (Mus musculus) PubMed

 2852.

fine-mapping the eui1 gene and identification of its candidate gene using in silico analysis based on previous research work and rice genomic sequence data [EUI1] (Mus musculus) PubMed

 2853.

OsDR8 has a role in disease resistance and thiamine accumulation [DR8] (Mus musculus) PubMed

 2854.

Xa5 potentially retain their basic transcription factor function, which, in turn, may mediate the novel pathway for bacterial blight resistance and susceptibility, respectively.[xa5] (Mus musculus) PubMed

 2855.

RNase-related protein is preferentially expressed in stems of wild-type rice and is significantly down-regulated in an increased tillering dwarf mutant ext37 [RNase-related protein] (Mus musculus) PubMed

 2856.

Results describe the DNA renaturation and strand exchange activities of OsDmc1 in real time, using fluorescence resonance energy transfer (FRET) [Dmc1]. (Mus musculus) PubMed

 2857.

OsRacB is only an accessory factor in plant salt tolerance [OsRacB] (Mus musculus) PubMed

 2858.

OsCRY1 is implicated in blue-light inhibition of coleoptile and leaf elongation during early seedling development in rice, and that the signaling mechanism of OsCRY1 involves direct interaction with OsCOP1 [CRY1b] (Mus musculus) PubMed

 2859.

The funtional characterization of MDP1 in O. sativa, including the effects of brassinolide on its expression and regualtion, is presented.[MDP1] (Mus musculus) PubMed

 2860.

Pi35(t) is associated with resistance to leaf blast. [Pi35(t)] (Mus musculus) PubMed

 2861.

Involved in cell division and might play diverse roles in differentation of panicles. (OsGASR1 and 2 = Oryza sativa GA-stimulated transcript-related gene 1 and 2) (Mus musculus) PubMed

 2862.

GER1 expression is induced by early light and jasmonate and its reponse to red light is controlled by phytochrome A and phytochrome B. [GER1] (Mus musculus) PubMed

 2863.

results substantiated our contention that OsPT6:1 encoded a high-affinity phosphate transporter of Oryza sativa (Mus musculus) PubMed

 2864.

According to high-sequence conservation, the rolled-leaf gene in rice could be orthologous to the Arabidopsis ZIP/Ago7 gene, named OsAGO7. [AGO7 proein] (Mus musculus) PubMed

 2865.

The transgenic plants over-expressing OCPI1 had significantly higher grain yield and seed setting rate than the wild type and under the severe drought stress conditions.[OCPI1 protein] (Mus musculus) PubMed

 2866.

confirmed that NPR1 is the rice orthologue of Arabidopsis NPR1 by complementing the Arabidopsis npr1 mutant; over-expression of NPR1 conferred disease resistance to bacterial blight, but also enhanced herbivore susceptibility in transgenic plants [NPR1] (Mus musculus) PubMed

 2867.

A mutation within the ALS gene confers highly specific resistance to pyrimidinyl carboxy (PC) herbicides. (Mus musculus) PubMed

 2868.

1) WOX3 acts as a transcriptional repressor of YAB3. [WOX3] 2) WOX3 acts as a transcriptional repressor of YAB3. [YAB3] (Mus musculus) PubMed

 2869.

DNA polymerase may be involved in a repair pathway similar to long-patch base excision repair. (Mus musculus) PubMed

 2870.

The rice (E)-beta-caryophyllene synthase (OsTPS3), an enzyme catalyzing the formation of volatile sesquiterpenes, plays a role in indirect defense of rice plants. (Mus musculus) PubMed

 2871.

The solution structure of OsCnfU-1A domain I (73-153). (Mus musculus) PubMed

 2872.

CONSTITUTIVELY WILTED1-mediated indole-3-acetic acid biosynthesis plays an important role in maintaining root to shoot ratios and, in turn, affects water homeostasis in rice[ CONSTITUTIVELY WILTED1] (Mus musculus) PubMed

 2873.

data suggest that OSH6 insertional mutant interferes with a developmental mechanism involved in bract differentiation, especially at the basal nodes of panicles [OSH6] (Mus musculus) PubMed

 2874.

In conclusion, the production of incorrect CMO transcripts results in a deficiency of the full-length choline monooxygenase protein and probably reduces glycine betaine accumulation considerably in rice plants. (Mus musculus) PubMed

 2875.

The tissues of rice seedlings grown in the presence of tryptamine exhibited a dose-dependent increase in serotonin in parallel with enhanced T5H enzyme activity. (T5H) (Mus musculus) PubMed

 2876.

Report of a novel male sterility gene, ms91(t), in a spontaneous mutant line (ms91(t). (Mus musculus) PubMed

 2877.

14-3-3 protein may play an important role in regulating ACS activity.(14-3-3) (Mus musculus) PubMed

 2878.

OsWRKY89 plays an important role in response to biotic and abiotic stresses. [WRKY89] (Mus musculus) PubMed

 2879.

Abscisic acid modulates post-transcriptional gene silencing through the transcriptional control of the OsRDR6 gene (OsRDR6). (Mus musculus) PubMed

 2880.

a slight increase in Eui expression could dramatically change rice morphology, indicating the practical application of the Eui gene in rice molecular breeding for a high yield potential. (Mus musculus) PubMed

 2881.

SNAC2 is a novel stress responsive NAC transcription factor that possesses potential utility in improving stress tolerance of rice. (Mus musculus) PubMed

 2882.

identification of a mutant gene that causes a significant decrease in the width of the leaf blade, termed narrow leaf 7 (nal7); results indicate that NAL7 is involved in auxin biosynthesis and controls leaf shape [NAL7] (Mus musculus) PubMed

 2883.

5'-UTR of the rice alcohol dehydrogenase gene contributes to efficient translation in not only dicotyledonous plant cells, but also in monocotyledonous rice cells .(Alcohol Dehydrogenase) (Mus musculus) PubMed

 2884.

Complementation tests showed that rice OsMADS22 and OsMADS47 are unable to reverse the flowering-time phenotypes of the svp and agl24 mutants in Arabidopsis. [MADS22, MADS47] (Mus musculus) PubMed

 2885.

characterisation of the frg gene in the Azucena variety, one of the few aromatic japonica cultivars [frg] (Mus musculus) PubMed

 2886.

OsRecQ1 is a homolog of Neurospora crassa QDE-3, and is required for RNA silencing for inverted repeat DNA, but not for dsRNA. [OsRecQ1] (Mus musculus) PubMed

 2887.

LPA1 is involved in phytic acid metabolism in rice. (Mus musculus) PubMed

 2888.

results suggested that ZFP177 might play crucial but differential roles in plant responses to various abiotic stresses. (Mus musculus) PubMed

 2889.

IPD3 represents a novel gene required for root symbiosis with arbuscular mycorrhizal fungi in plants [IPD3] (Mus musculus) PubMed

 2890.

Activation of Ehd1 by OsId1 is required for the promotion of flowering. [Ehd1; OsId1] (Mus musculus) PubMed

 2891.

GluD-1 is maximally expressed in the starchy endosperm starting at 5 d after flowering. [GluD-1] (Mus musculus) PubMed

 2892.

OsRpl6-1 and OsRpl6-2 have an intron in the 5'-untranslated region, suggesting a gene duplication after its transfer to the nucleus. [Rpl6-2] (Mus musculus) PubMed

 2893.

PHR1 is a polyphenol oxidase that contributes to grain discoloration during storage. [PHR1] (Mus musculus) PubMed

 2894.

Results indicated that FLEXIBLE CULM1 (FC1), encoding a cinnamyl-alcohol dehydrogenase, plays an important role in the biosynthesis of lignin and the control of culm strength in rice: [FC1] (Mus musculus) PubMed

 2895.

NL1 is an intrinsic factor that modulates and coordinates organogenesis through regulating the expression of PLA1 and other regulatory genes during reproductive development in rice. (Mus musculus) PubMed

 2896.

2 low phytic acid lines, Os-lpa-XS110-2 & Os-lpa-XS110-3 were identified to carry 2 allelic mutations of rice orthologue, OsMRP5, of maize Lpa1 gene; evidence indicates that the OsMRP5 gene plays an important role in PA metabolism in rice seeds [MRP5] (Mus musculus) PubMed

 2897.

The rice SDS and RCK are expressed in young flowers, and transgenic rice lines with reduced expression of these genes exhibited normal vegetative development, but showed reduced fertility with partially sterile flowers and defective pollens. (Mus musculus) PubMed

 2898.

The cloning, structure, and characterization of 3BGlu6, a beta-glucosidease, in Oryza satival is reported.[3BGlu6] (Mus musculus) PubMed

 2899.

clone and characterize DST, a previously unknown zinc finger transcription factor that negatively regulates stomatal closure by direct modulation of genes related to H(2)O(2) homeostasis [DST (drought and salt tolerance)] (Mus musculus) PubMed

 2900.

Missense mutation in OsCESA4 (G858R), a highly conserved residue at the end of the fifth transmembrane domain, results in growth retardation and dramatically reduced plant strength. [CESA4] (Mus musculus) PubMed

 2901.

We identified the N15 antirepressor gene, antC, and showed that its product binds to and acts against the main phage repressor, CB.[AntC] (Mus musculus) PubMed

 2902.

P1 is required for systemic spread of virus; in Sf9 cells P1 localizes in the fraction of membranes and inclusions but not in soluble cytoplasmic protein fraction [P1 protein] (Mus musculus) PubMed

 2903.

Partial proteolysis revealed that the DNA-binding domain of LEF-3 is located within a central region (residues 28 to 326) that is relatively resistant to proteolysis.[Lef-3] (Mus musculus) PubMed

 2904.

Our results demonstrate that ac18 is not essential for viral propagation both in vitro and in vivo, but it may play a role in efficient virus infection in T. ni larvae. [ac18] (Mus musculus) PubMed

 2905.

We concluded that the gene products encoded from these Ac 101, Ac 142, or the Ac 144 open reading frames are essential for virus production and may be involved in DNA processing, packaging, or nucleocapsid morphogenesis. [Ac 101, Ac 142, Ac 144] (Mus musculus) PubMed

 2906.

These results suggest that ac66 plays an important role for the efficient exit of nucleocapsids from the nucleus to the cytoplasm for budded virus synthesis as well as for preoccluded virion and occlusion synthesis.[ac66] (Mus musculus) PubMed

 2907.

Induction of apoptosis and budding virus formation occurs in AcMNPV FP-25/p35 double mutant infected Trichoplusia ni cells. [FP-25] (Mus musculus) PubMed

 2908.

Domain mapping results showed that all the six domains were required but deletion of the N-terminal acidic region and the leucine zipper domains had the greatest impact on BV production.[Exon0] (Mus musculus) PubMed

 2909.

integrity of the ac142-ac143 core gene cluster was required for the bacmids to display wild-type patterns of viral replication, BV production and RNA transcription.[ac142, ac143] (Mus musculus) PubMed

 2910.

38K is a novel nucleocapsid protein and provide a rationale for why 38K is essential for nucleocapsid assembly [nucleocapsid protein ] (Mus musculus) PubMed

 2911.

a functional nuclear localization domain on LEF-3 was required for interaction between LEF-3 and P143. [LEF-3] (Mus musculus) PubMed

 2912.

P35, a caspase inhibitor, is required for robust virion production in Trichoplusia cells. [P35] (Mus musculus) PubMed

 2913.

The core protein AC109 is essential for AcMNPV to be able to mount a successful infection. [ac109] (Mus musculus) PubMed

 2914.

molecular cloning of a ubiquitin homologue in Spodoptera litura nucleopolyhedrovirus [ubiquitin] (Mus musculus) PubMed

 2915.

These results suggest that moricin is present not only in Bombyx mori but also in other lepidopteran insects forming a gene family. (Mus musculus) PubMed

 2916.

results suggest that identified SpltNPV-I ORF codes for a serine/threonine kinase. [pk1] (Mus musculus) PubMed

 2917.

Splt-iap4 has no antiapoptotic function during SpltNPV infection. (Mus musculus) PubMed

 2918.

F protein proved to be a functional analogue of GP64, is present as an oligomer, and possess N-inked glycans [F protein] (Mus musculus) PubMed

 2919.

results indicate that the F protein is essential for baculovirus budded virus (BV) infectivity and that the cytoplasmic tail domain is important for F protein incorporation into BV [F protein] (Mus musculus) PubMed

 2920.

These results indicate that N-linked glycosylation of the HearNPV baculovirus F(2) subunit is not essential for viral infectivity and suggest that it is involved in BV production and fusogenicity. [F protein] (Mus musculus) PubMed

 2921.

These results demonstrate that group II NPV F proteins can be functionally replaced with a homologue of other group II NPVs, suggesting that the interaction of F with other viral or host proteins is not absolutely species-specific. [F protein] (Mus musculus) PubMed

 2922.

The putative ACE from the phytopathogenic bacterium, Xanthomonas axonopodis pv. citri, named XcACE was cloned and characterized.(Angiotensin-converting enzyme) (Mus musculus) PubMed

 2923.

(Maltose-binding protein; MalE) Study of the crystal structure and organization of MalE will shed light on the mechanism of sugar transport in Xanthomonas species as well as in other phytopathogenic bacteria. (Mus musculus) PubMed

 2924.

The cloning, expression, purification and crystallization of PilZ(XAC1133), a protein consisting of a single PilZ domain from Xanthomonas axonopodis pv. citri, is reported.[PilZ] (Mus musculus) PubMed

 2925.

The glycoprotein E2, classical swine fever virus expressed in C. reinhardtii chloroplasts could elicit animal bodies to produce antibodies against protein E2. (Mus musculus) PubMed

 2926.

proteasomal degradation of interferon regulatory factor 3 is induced by a direct or indirect interaction with N(pro)[Npro] (Mus musculus) PubMed

 2927.

Mutations in the carboxyl terminal region of E2 are responsible for viral attenuation. (E2 glycoprotein) (Mus musculus) PubMed

 2928.

Expression of NS2-3 and NS4A in trans restored the production of infectious particles from genomes lacking NS2-3 expression and indicate that NS2-3 and NS3, each in association with NS4A, have independent functions in the CSFV life cycle.[NS2-3, NS4A] (Mus musculus) PubMed

 2929.

AngM is a nonribosomal peptide synthetase (with peptidyl carrier protein and condensation domains) essential in the biosynthesis of anguibactin. [AngM] (Mus musculus) PubMed

 2930.

EmpA is secreted as a approximately 48-kDa proenzyme and that activation occurs extracellularly by the removal of a approximately 10-kDa peptide. [EmpA] (Mus musculus) PubMed

 2931.

Four nucleotide sequences showing homology to known hemolysin genes were cloned and sequenced from V. anguillarum strain H775 and demonstrated hemolytic acitivites against fish, sheep, rabbit erythrocytes [Vah2, VAh3, Vah4, Vah5] (Mus musculus) PubMed

 2932.

These data show that Epp is the EmpA-processing protease.[Epp in strain M93S] (Mus musculus) PubMed

 2933.

receptor-binding protein head domain structure from Lactococcus lactis phage bIL170 [receptor-binding protein] (Mus musculus) PubMed

 2934.

sNiV-G binds to ephrinB3 with a 30-fold higher affinity than that of sHeV-G.(sHeV-G) (Mus musculus) PubMed

 2935.

the crystal structure of the Yokose virus methyltransferase at 1.7A resolution was presented. (methyltransferase) (Mus musculus) PubMed

 2936.

[genome-linked viral protein, VPg] The VPg sequence determined was found to be triplicated in the nonstructural protein precursor. Multiple VPg-like sequences were also found in 10 of the 12 dicistroviruses examined. (Mus musculus) PubMed

 2937.

crystal structure of 2C-methyl-D-erythritol-2,4-cyclophosphate synthase [2C-methyl-D-erythritol-2,4-cyclophosphate synthase] (Mus musculus) PubMed

 2938.

Results describe the genetic organization of the hrp gene cluster in Erwinia pyrifoliae and characterize HR active domains in HrpNEp protein by mutational analysis [HrpN]. (Mus musculus) PubMed

 2939.

rstC gene of vibriophage fs2 integrates into the intergenic region 1 of chromosome 1 of V. cholerae O1 and O139. [rstC] (Mus musculus) PubMed

 2940.

The Orf135 protein may be involved in suppressing mutations induced by oxidized deoxynucleotides (Orf135 protein). (Mus musculus) PubMed

 2941.

structure of EcAIII, the isoaspartyl peptidase with L-asparaginase activity from Escherichia coli (Mus musculus) PubMed

 2942.

nmr assignment of the 23 kDa organomercurial lyase MerB in its free and mercury-bound forms [MerB] (Mus musculus) PubMed

 2943.

three-dimensional structure of Par10 [PAR10] (Mus musculus) PubMed

 2944.

x-ray crystallographic studies of the Afa/Dr adhesin DraE and its interaction with chloramphenicol (Mus musculus) PubMed

 2945.

dats show that the host intermediate filament protein cytokeratin 18 (CK18) is an interacting partner of EspF during enteropathogenic Escherichia coli (EPEC) pathogenesis [EspF] (Mus musculus) PubMed

 2946.

blue light-regulated phosphodiesterase plays a protective role in response to oxidative stress [blue light-regulated phosphodiesterase] (Mus musculus) PubMed

 2947.

role in initiating the mitochondrial death pathway. [EspF] (Mus musculus) PubMed

 2948.

crystal structure (gamma-glutamylcysteine Synthetase) (Mus musculus) PubMed

 2949.

iucA is associated with virulence in avian pathogenic Escherichia coli (APEC) after exposure by the natural route of infection.[iucA] (Mus musculus) PubMed

 2950.

E. coli K1 invasion occurs through the CNF1-67-kDa laminin receptor interaction [CNF1] (Mus musculus) PubMed

 2951.

colicin A release was studied and the role played by Cal during secretion was investigated [Cal] (Mus musculus) PubMed

 2952.

Hsp31 has roles as both chaperone and peptidase [Hsp31, also called hchA] (Mus musculus) PubMed

 2953.

To estimate the prevalence of Shiga toxin producing Escherichia coli in Australia, bloody stool samples from two Australian locations were screened for the presence of Shiga toxin genes, stx1 and stx2. [stx1, stx2] (Mus musculus) PubMed

 2954.

expression regulated by lrp as influenced by alanine and leucine [F165 1] (Mus musculus) PubMed

 2955.

structural model for NDH-2 through comparative modelling onto a template from this family [NDH-2] (Mus musculus) PubMed

 2956.

Crystallographic analysis of the heterodimeric CesA-EspA complex at a resolution of 2.8 A reveals that EspA contains two long a-helices, which are involved in extensive coiled-coil interactions with CesA [CesA & EspA] (Mus musculus) PubMed

 2957.

EPEC PerC can activate both the EPEC and EHEC LEE1 promoters and the major transcriptional start site is similarly located in both organisms [PerC] (Mus musculus) PubMed

 2958.

analysis of morphinone reductase reaction with 2-cyclohexen-1-one and 1-nitrocyclohexene [morB] (Mus musculus) PubMed

 2959.

monomers of HlyB can interact at least transiently and are the important species during ATP hydrolysis [HlyB] (Mus musculus) PubMed

 2960.

the two homologous halves of the ArsA may be functionally nonequivalent [ArsA] (Mus musculus) PubMed

 2961.

LT(K63/R72) exhibits characteristics more closely related to LT(K63) than LT(R72)[heat-labile enterotoxin LT] (Mus musculus) PubMed

 2962.

HosA is involved in temperature-dependent control of swimming motility and cellular aggretation [HosA] (Mus musculus) PubMed

 2963.

findings show that EscJ comprises two subdomains (D1 - amino acid residues 1-55 in the mature protein, and D2 - amino acid residues 90-170), each comprising a three-stranded beta-sheet flanked by two alpha-helices (Mus musculus) PubMed

 2964.

Pro-sequence and Ca2+-binding of Ntn-hydrolase penicillin amidase [pro-PA] (Mus musculus) PubMed

 2965.

A new variant of the E. coli intimin protein (eae) is reported in cattle.[eae] (Mus musculus) PubMed

 2966.

The peripheral stalk of F(1)F(0) ATP synthase is composed of a parallel homodimer of b subunits that extends across the cytoplasmic membrane. (f1f0-atp synthase) (Mus musculus) PubMed

 2967.

with TrwB structural similarity to F1-ATPase, a mechanism for TrwB as a DNA-translocating motor is proposed [TrwB] (Mus musculus) PubMed

 2968.

We have expressed the full-length and half domains of bovine bone sialoprotein in a prokaryotic system and identified the phosphorylation sites of casein kinase II. [casein kinase II] (Mus musculus) PubMed

 2969.

in GRP94, ATP binding dictates the conformation of the N-domain and regulates its ability to form quaternary structural interactions [GRP94] (Mus musculus) PubMed

 2970.

in extraintestinal Escherichi coli infections, no HylaA+ sheA+ strains were identified, suggesting possible incompatibility between HlyA and SheA in the chromosome of E. coli [HlyA] (Mus musculus) PubMed

 2971.

QnrA binds to topoisomerase IV and its subunits in a reaction that does not depend on the presence of DNA, quinolone, or ATP [QnrA, quinolone resistance protein] (Mus musculus) PubMed

 2972.

Arg-70 influences catalysis in HpaI at the pyruvate proton exchange step; highest activity for HpaI is found with Co2+ and Mn2+ as the cofactor. (HpaI; multifunctional; pyruvate-specific class II aldolase) (Mus musculus) PubMed

 2973.

The nucleotide-binding domain of the HlyB transporter is characterized with respect to its uncoupled ATPase activity, oligomeric state, and stability in solution. (HlyB) (Mus musculus) PubMed

 2974.

The alkyltransferase-like (ATL) protein inhibited the transfer of methyl groups to O6-methylguanine-DNA methyltransferase (ATL). (Mus musculus) PubMed

 2975.

The SXN motif of PBP 5, and especially Ser110, is intimately involved in the catalytic mechanism of deacylation. (Mus musculus) PubMed

 2976.

structures of the wild-type and the S70G TEM-1 beta-lactamase determined to 1.55 and 2.1 A, respectively, are presented [TEM-1 beta-lactamase] (Mus musculus) PubMed

 2977.

new insights on the structural properties and temperature stability of the calcium depleted D-galactose/D-glucose-binding protein (GGBP) contribute to better understanding of the protein function [D-galactose/D-glucose-binding protein] (Mus musculus) PubMed

 2978.

both a large cell-surface protein designated Contact-dependent inhibitor A (CdiA) and two-partner secretion family member CdiB were required for contact-dependent growth inhibition [CdiA, CdiB] (Mus musculus) PubMed

 2979.

This result demonstrates an essential role for Ler in in vivo pathogenicity of attaching/effacing (A/E) E. coli. (Mus musculus) PubMed

 2980.

Modulation of polymorphonuclear leukocyte (PMN) function by CNF1 facilitates uropathogenic Escherichia coli (UPEC)survival during the acute inflammatory response [cytotoxic necrotizing factor type 1; CNF1] (Mus musculus) PubMed

 2981.

hydrophilic domain II of the structural fimbrial subunit DraE may be involved in cell entry (DraE) (Mus musculus) PubMed

 2982.

Opening and closing of the catalytic chain domains of aspartate transcarbamoylase explains how the catalytic cycle occurs while the enzyme remains globally in the R-quaternary structure. (Mus musculus) PubMed

 2983.

study showed that the lpfA genes identified in the genome of shiga toxin-producing Escherichia coli (STEC) strains are not specific to this category; results suggest that there is a relationship between the lpfA variant and the phylogenetic group [lpfA] (Mus musculus) PubMed

 2984.

a molecular chaperone involved in recruiting multiple type III effectors to the T3SS via EscN for efficient secretion [CesT] (Mus musculus) PubMed

 2985.

Data describe the post-transcriptional regulation of the biosynthesis of the periplasmic protein, penicillin amidase [penicillin amidase] (Mus musculus) PubMed

 2986.

type-I methionyl aminopeptidases (MetAPs) can be selectively targeted over type-II MetAPs [type-I MetAPs and type-II MetAPs] (Mus musculus) PubMed

 2987.

EspG alters epithelial paracellular permeability.(Espg) EspG2 alters epithelial paracellular permeability.(Espg2) (Mus musculus) PubMed

 2988.

EspB protein (312 residues in total) has functions associated with its different regions. These regions may interact with each other or with other components of the type III system to orchestrate the intricate actions of EHEC during infection. [EspB] (Mus musculus) PubMed

 2989.

molecular characterization of the organomercurial lyase merB gene from the different wild broad-spectrum E. coli isolates from the Indian subcontinent [merB] (Mus musculus) PubMed

 2990.

crystal structures of ecLeuRS-ED (the editing domain of Escherichia coli LeuRS) in both the apo form and in complexes with Met and Ile at 2.0 A, 2.4 A, and 3.2 A resolution respectively.[leucyl-trna synthase] (Mus musculus) PubMed

 2991.

AAA+ ATPases are ubiquitous proteins that employ the energy obtained from ATP hydrolysis to remodel proteins, DNA, or RNA. (AAA+ atpase) (Mus musculus) PubMed

 2992.

description of DHA-1 cephalosporinase production in E. coli [DHA-1] (Mus musculus) PubMed

 2993.

fraction of alpha-haemolysin is located within outer membrane vesicles that are released by the bacteria; propose an alternative pathway for the transport of alpha-haemolysin from the bacteria to host cells during bacterial infections [alpha-haemolysin] (Mus musculus) PubMed

 2994.

There is a direct functional role for the 14-3-3tau:Tir interaction in E.coli infection. (Mus musculus) PubMed

 2995.

K-API is now the second Kdo biosynthetic related gene that has been characterized from the kps group 2 capsule cluster [kpsF] (Mus musculus) PubMed

 2996.

evolutionarily related family of aldolases distinct from the N-acetylneuraminate lyase (NAL) family [2-keto-3-deoxy-6-phosphogluconate aldolase] (Mus musculus) PubMed

 2997.

analysis of hydrolysis of ATP by aminoglycoside 3'-phosphotransferase [APH3'Ia] (Mus musculus) PubMed

 2998.

The KpsD protein, previously believed to be a periplasmic protein, is an outer membrane protein involved in the export of group 2 capsular polysaccharides across the outer membrane. (Mus musculus) PubMed

 2999.

random mutagenesis studies suggest that EspB has distinct domain functions involved in effector translocation that can be distinguished from its role as a component of the translocation pore. [EspB] (Mus musculus) PubMed

 3000.

the ArsA ATPase Cys-113 and Cys-422 form a high affinity metalloid binding site [ArsA] (Mus musculus) PubMed

 3001.

results showed that three nonpolar amino acids at positions 381-383 (Phe-Leu-Leu) of AatA were required for export of dispersin, and these residues were located at the base of carboxy-terminal elongation in the equatorial domain of AatA [AatA, dispersin] (Mus musculus) PubMed

 3002.

preliminary crystallographic analysis of 2,4-dihydroxy-hepta-2-ene-1,7-dioate aldolase, HpcH [HpcH] (Mus musculus) PubMed

 3003.

crystallization of cytolethal distending toxin (CdtB); CdtB crystals contain one molecule of MW 30.5 kDa per asymmetric unit, belong to space group P2(1)2(1)2(1) and diffract to 1.72 A [CdtB] (Mus musculus) PubMed

 3004.

solved the crystal structure of the N-terminal relaxase domain of TrwC in complex with a 27 base-long DNA oligonucleotide that contains both the recognition hairpin and the scissile phosphate (Mus musculus) PubMed

 3005.

The role of the CvaB protein c-terminal domain in the synthesis of colicin V in E. coli is reported.[CvaB] (Mus musculus) PubMed

 3006.

The role of polyamines in the expression and effects of ColE7 in E. coli are reported.[ColE7] (Mus musculus) PubMed

 3007.

Two-partner secretion locus etpBAC directs secretion of a high-molecular-weight glycosylated protein, EtpA, that in concert with the putative EtpB transporter participates in adherence of enterotoxigenic strain H10497 to epithelial cells. (EtpA, EtpB) (Mus musculus) PubMed

 3008.

results indicate that EscC, EscD, and EscJ are required for the formation of the TTS (Type III Secretion) apparatus [EscC, EscD, EscJ] (Mus musculus) PubMed

 3009.

identified sorting nexin 9 (SNX9) as a host cell EspF binding partner protein, which binds EspF via its amino-terminal SH3 region [EspF] (Mus musculus) PubMed

 3010.

transcription control by Fit factors in vivo are discussed [fitA, fitB & fitC4] (Mus musculus) PubMed

 3011.

The mechanisms underlying the Ca2+ oscillations induced by alpha-hemolysin are reported.[HlyA] (Mus musculus) PubMed

 3012.

tRNase Z cleaves several unstructured RNAs other than pre-tRNAs, with a tendency to cleave after cytidine or before uridine [tRNase Z] (Mus musculus) PubMed

 3013.

EspF-mediated inhibition of PI-3 kinase-dependent uptake: (i) is independent of mitochondrial targeting, (ii) requires the N-terminal domain and (iii) the C-terminal domain is sufficient to disrupt barrier function but not inhibition of bacterial uptake. (Mus musculus) PubMed

 3014.

The mechanism of tetracycline resistance was studied using expression studies in E. coli mutants that were defective in the tet(A) and the tolC proteins.[tet9A)] (Mus musculus) PubMed

 3015.

Study indicates that M.EcoHK31I is composed of polypeptides alpha and beta. The N-terminal region of polypeptide beta takes part in subunit interaction, while the C-terminal region is involved in DNA binding [M.EcoHK31I ] (Mus musculus) PubMed

 3016.

evidence for chromosomal location of blaVIM-2 & blaGES-7 genes carried by a clinical isolate; the blaVIM-2 gene has been found on a class I integron, designated In8 [blaVIM-2, blaGES-7] (Mus musculus) PubMed

 3017.

mutagenesis and crystallographic studies of DaaE; Naturally occurring variants and directed mutations in DaaE have been generated and analyzed for their ability to bind DAF(DaaE) (Mus musculus) PubMed

 3018.

EilA contributes to virulence and activates the genetically linked high molecular weight bacterial surface protein Air [EILA] (Mus musculus) PubMed

 3019.

Mutagenesis and chemical rescue data implicate the C-proximal Arg320, Glu324 and, possibly, His356 in catalysis by PrrC-anticodon nuclease (PrrC). (Mus musculus) PubMed

 3020.

HbiF-mediated OFF-to-ON fimS molecular switching is independent of FimB and FimE. (HbiF) (Mus musculus) PubMed

 3021.

(p)ppGpp regulates transcription of fimB promoter. (Mus musculus) PubMed

 3022.

X-ray structure of the CdtB subunit (Escherichia coli-II CdtB, EcCdt) (Mus musculus) PubMed

 3023.

we examine stability & folding/unfolding kinetics of Lpp-56 at neutral pH using GdmCl as denaturant. Folding & unfolding appear to represent structural transitions between folded trimer & unfolded monomer, without detectable intermediates[Lpp-56] (Mus musculus) PubMed

 3024.

The catalytic cycle of isolated ATP-binding cassette (ABC)-transporter-nucleotide-binding domains of HlyB is divided into distinct steps that involve different conserved sequence motifs as key players, acting to coordinate intramolecular movements. (Mus musculus) PubMed

 3025.

OMVs provide a means for delivery of cytotoxic necrotizing factor type 1 (CNF1) from a UPEC strain to PMNs and thus negatively affect the efficacy of the acute inflammatory response to these organisms. [CNF1] (Mus musculus) PubMed

 3026.

aldose sugar dehydrogenase from Escherichia coli has a highly exposed active site conferring broad substrate specificity [Asd] (Mus musculus) PubMed

 3027.

The induction of MdtEF expression in E. coli by multiple compounds, including GlcNAc, is presented. (Mus musculus) PubMed

 3028.

High level expression of full length and truncated myocilins in E. coli. Bacterial and eukaryotic recombinant full length myocilin produced similar biological effect on trabecular meshwork cells. Phenotype largely due to the NH(2)-terminal half. (Mus musculus) PubMed

 3029.

Study provides evidence that the secreted autotransporter toxin, Sat, acts as a virulence factor in Afa/Dr diffusely adhering Escherichia coli (DAEC) by promoting lesions in tight junctions of polarized epithelial Caco-2 cells [Sat] (Mus musculus) PubMed

 3030.

analysis of the structure of R- and T-state Escherichia coli aspartokinase III (Mus musculus) PubMed

 3031.

influence of the ung, dug, and dut genes in preventing uracil residues from accumulating in E. coli DNA was quantitatively determined [double-strand uracil-DNA glycosylase (dug)] (Mus musculus) PubMed

 3032.

The first structural characterization of gentisate 1,2-dioygenase from the pathogenic O157:H7 Escherichia coli strain was reported. (Mus musculus) PubMed

 3033.

Secreted autotransporter toxin, a serine protease, enters human bladder and kidney epithelial cells and localizes specifically to the cytoskeletal fraction where proposed protein targets reside. (secreted aurotransporter toxin) (Mus musculus) PubMed

 3034.

GpUp is the minimal substrate strictly retaining specificity for ribonuclease activity by the Colicin E5 C-terminal domain (Colicin E5). (Mus musculus) PubMed

 3035.

Two new crystal structures (free enzyme and enzyme-substrate complex), NMR, and site-directed mutagenesis data, suggest a four-stage catalytic cycle for the enzyme GDP-mannose mannosyl hydrolase. [Yefc protein] (Mus musculus) PubMed

 3036.

These results show that diffuse positive charge associated with the C-terminal subdomains of EcoRV plays a key role in DNA association, bending, and cleavage.[EcoRV] (Mus musculus) PubMed

 3037.

The reaction of glutamate mutase with the glutamate analogue, 2-thiolglutarate, was analysed. (Mus musculus) PubMed

 3038.

OmpA facilitates the interaction of E. coli with human brain microvascular endothelial cells. (Mus musculus) PubMed

 3039.

EibG acts as an IgG Fc- and IgA-binding protein, as well as an adhesin of LEE-negative Shiga toxin-producing Escherichia coli.(EibG) (Mus musculus) PubMed

 3040.

Homotropic cooperative interactions between the catalytic sites for the binding of aspartate are explained by a quaternary structure transition from T state (aspartate low affinity) to R state (aspartate high affinity). (Mus musculus) PubMed

 3041.

observations suggest that dissociation of the colicin E2 immunity protein occurs at the outer membrane surface and requires full translocation of the colicin E2 N-terminal domain [colicin E2 immunity protein] (Mus musculus) PubMed

 3042.

Study shows that relaxase TrwC promotes recombination between two directly repeated oriTs while related relaxases TraI of F and pKM101 do not. [TrwC protein] (Mus musculus) PubMed

 3043.

heat-labile enterotoxin B subunit pentamer (EtxB5) assembly in vitro is inhibited using monoclonal antibodies (Mus musculus) PubMed

 3044.

experiments suggest that the proteolytic processing of AIDA-I plays a minor role in the functionality of this protein in adhesion. [AIDA-I] (Mus musculus) PubMed

 3045.

NMR studies suggest that dilution of the chaotrope to initiate refolding will result in collapse of the clusters, leading to the formation of persistent helical structure and the three-helix folding intermediate.(colicin immunity protein Im7) (Mus musculus) PubMed

 3046.

The nascent RNA-mediated destabilization of an interaction between sigma(70) region 4 and the flap domain of the beta subunit is required for the bacteriophage lambda Q antiterminator protein to contact holoenzyme during early elongation. (Mus musculus) PubMed

 3047.

The results of these experiments show that while the target size of the catalytic activity for K92 polysialyltransferase is larger than a monomer of NeuS, a large complex is not required for catalysis.[NeuS polysialyltransferase] (Mus musculus) PubMed

 3048.

Crystal structures of colicin E5-C-terminal domain complexed with its substrate analog and ImmE5 clearly demonstrate the mechanism by which specific substrate recognition is achieved (colicin E5). (Mus musculus) PubMed

 3049.

structure of Escherichia coli PapI, a key regulator of the pap pili phase variation [PapI] (Mus musculus) PubMed

 3050.

Ser503 and Gln504 in aromatic stacking region of CvaB block the ATP binding and are important for the GTP-binding preference[CvaB] (Mus musculus) PubMed

 3051.

Reconstruction of an N-terminal truncate rendered FedF amenable to crystallization, resulting in crystals with space group P2(1)2(1)2(1) and unit-cell parameters a = 36.20, b = 74.64, c = 99.03 A that diffracted to beyond 2 A resolution[FedF] (Mus musculus) PubMed

 3052.

Overall activities of the purified GmrSD enzyme are in good agreement with the properties of the cloned gmr genes in vivo and suggest a restriction enzyme specific for sugar modified hydroxymethylcytosine DNAs.[GmrS, GmrD] (Mus musculus) PubMed

 3053.

Stx1 activates both apoptotic and cell survival signaling pathways in human macrophage-like myelogenous leukemia THP-1 cells. (Stx1; Shiga toxin 1) (Mus musculus) PubMed

 3054.

When an SSB variant that lacks the C-terminal 8 amino acids is used, the capacity of RecOR to facilitate RecA loading onto the ssDNA is largely abolished[SSB protein] (Mus musculus) PubMed

 3055.

IIANtr regulates the K+ transporter TrkA [IIANtr] (Mus musculus) PubMed

 3056.

The PapG II adhesin can enhance the early establishment of E. coli infection in the kidney [PapG II adhesin]. (Mus musculus) PubMed

 3057.

This is the first report which documents the cell surface-to-ER and ER-to-cytosol trafficking of a bacterial non-AB toxin, Plasmid-encoded toxin. [Pet] (Mus musculus) PubMed

 3058.

Study provides evidence for the molecular basis for the enhanced spontaneous mutator activity of RumA'B as well as explains its ability to promote efficient and accurate bypass of T-T pyrimidine dimers in vivo. [RumA'B protein, Bacteria] (Mus musculus) PubMed

 3059.

The dimeric ImE7 protein is involved in a sequence-specific cleavage at the ceiE7 mRNA (ImE7). (Mus musculus) PubMed

 3060.

These results demonstrate for the first time that STb can permeabilize its target membrane and suggest that it does so by forming nonspecific pores on piglet jejunal brush border membrane vesicles. (Mus musculus) PubMed

 3061.

A proposed model in which transcriptional repression of the parD operon is tuned by the relative molar ratio of the Kid antitoxin and Kis toxin protein (Kid and Kis). (Mus musculus) PubMed

 3062.

These results suggest that IbeA interacts with polypyrimidine tract-binding protein (PTB)-associated splicing factor (PSF) for the E. coli K1 invasion of HBMEC.[IbeA] (Mus musculus) PubMed

 3063.

the calcium-binding C-terminal domain of Escherichia coli alpha-hemolysin is a major determinant in the surface-active properties of the protein [HlyA] (Mus musculus) PubMed

 3064.

We have used phosphorescence spectroscopy to investigate the effects of glucose and calcium on the dynamics and stability of GGBP. (GGBP) (Mus musculus) PubMed

 3065.

6S RNA interferes with transcription initiation and also acts as a template for the transcription of defined RNA molecules in the absence of DNA (6S RNA). (Mus musculus) PubMed

 3066.

The subcellular targeting of E. coli K99 FanC to chloroplasts of transgenic soybeans is reported.[FanC] (Mus musculus) PubMed

 3067.

These studies suggest that QseA activates the transcription of LEE1 by directly binding upstream of its P1 promoter region. [QseA] (Mus musculus) PubMed

 3068.

The passenger domain of the Escherichia coli O157:H7 autotransporter EspP is released in a novel autoproteolytic reaction.[EspP] (Mus musculus) PubMed

 3069.

TraY and IHF recognize sbyA and ihfA with limited sequence specificity and with relaxosome proteins requiring proper spacing and orientation with respect to each other[traY and IHF] (Mus musculus) PubMed

 3070.

UDP-hexose 4-epimerase gene was found & characterized to be able to catalyze interconversion between UDP-GlcNAc/GalNAc and UDP-Glc/Gal with almost equal efficiency Deletion of gne1 in O86:B7 mutant exhibited rough LPS[gne1] (Mus musculus) PubMed

 3071.

The aim of this study was to determine if tccP2 is found in atypical EPEC isolated from human and farm animals; tccP2 was found at a frequency of 41% in non-O26 EPEC isolates and in 82.3% of the O26 strains. [tecP2 protein] (Mus musculus) PubMed

 3072.

short and long range residue motions could play an important catalytic role in TEM-1 beta-lactamase [TEM-1] (Mus musculus) PubMed

 3073.

The cytotoxic necrotizing factors CNF1 and CNF2 of Escherichia coli and CNF(Y) of Yersinia pseudotuberculosis bind to different cellular receptors but are released into the cytosol from acidified endosomes. [CNF1 and CNF2] (Mus musculus) PubMed

 3074.

The junction region of the passenger domain in AIDA-I is involed in the biogenesis of AIDA-I by interacting with and/or promoting folding of native passenger domains. [AIDA-I] (Mus musculus) PubMed

 3075.

Access to a bona fide wild-type PcoC protein allowed unequivocal observation of intermediates involved in intermolecular redox copper transfer reactions[PcoC] (Mus musculus) PubMed

 3076.

Isolates lacking papGII were more frequent among patients with urinary tract abnormalities (58% vs. 10%, p 0.0003), as were non-virulent phylogenetic group A isolates (25% vs. 5%, p 0.043)in E. coli causing pyelonephritis in children. [PapGII] (Mus musculus) PubMed

 3077.

Results show that the N-terminal extension of PapF is required to adapt the PapG adhesin to the tip of the fiber [PapF,PapG] (Mus musculus) PubMed

 3078.

Studies suggest that CexE may be a novel ETEC virulence factor because its expression is controlled by the virulence regulator CfaD [CfaD and CexE] (Mus musculus) PubMed

 3079.

analysis of catalytic residues of the cyclase NisC involved in the biosynthesis of nisin [NisC] (Mus musculus) PubMed

 3080.

identification of the VIM-1/VIM-2 hybrid metallo-beta-lactamase VIM-12 gene in a clinical isolate.[VIM-12] (Mus musculus) PubMed

 3081.

strains belonging to EPEC 2 can trigger actin polymerization using both Nck and TccP2 actin-polymerization signalling cascades.[TccP2 protein] (Mus musculus) PubMed

 3082.

Free methionine-(R)-sulfoxide reductase (fRMsr) is 100- to 1,000-fold more active than non-selenocysteine-containing MsrB enzymes for free Met-(R)-O. [fRMsr] (Mus musculus) PubMed

 3083.

The CTX-M-14 ESBL in E. coli isolates is the result of the convergence of two different genes.[CTX-M-14] (Mus musculus) PubMed

 3084.

Modelling substrate into the active site suggests the attacking water molecule is not part of the metal coordination shell [HpcG] (Mus musculus) PubMed

 3085.

The carboxyl-terminal regions of TraG and Eex were found to localize in the cell cytoplasm; suggesting that complex topological rearrangements of conjugative proteins must occur during mating to enable these domains to interact.[Eex,TraG] (Mus musculus) PubMed

 3086.

The 2.5 A crystal structure of the receptor-binding B-subunit of hLT in complex with the blood group A antigen analog provides evidence of a previously unknown binding site in the native toxin.[enterotoxin LT] (Mus musculus) PubMed

 3087.

analysis of structural model of the R state of Escherichia coli aspartate transcarbamoylase with substrates bound [aspartate transcarbamoylase] (Mus musculus) PubMed

 3088.

Peptide mimicry and Cys-mediated intersubunit cross-linking data suggest that the tRNALys-binding motif of PrrC is shared by C-domain portions interfacing in parallel (PrrC). (Mus musculus) PubMed

 3089.

We found that 3'-phosphoadenosine 5'-phosphate phosphatase (CysQ) of Escherichia coli exhibited NADP(H) phosphatase and fructose-1,6-bisphosphatase activities. [CysQ] (Mus musculus) PubMed

 3090.

there is strong coupling between cyclic nucleotide binding and MloK1 channel opening [MloK1] (Mus musculus) PubMed

 3091.

F1-ATPase of the F(O)F1 ATP synthase complex involves rotation of the central gamma subunit relative to the catalytic sites in the alpha3beta3 pseudo-hexamer. We name this step k(gamma). (Mus musculus) PubMed

 3092.

description of facile room-temperature protolytic cleavage by a thiol of the Hg-C bond in mercury-alkyl compounds that emulate the structure and function of the organomercurial lyase MerB [MerB] (Mus musculus) PubMed

 3093.

inhibition of conjugative relaxases is a potentially novel antimicrobial approach[DNA relaxase] (Mus musculus) PubMed

 3094.

Hygromycin B phosphotransferase (Hph; EC 2.7.1.119) converts hygromycin B to 7''-O-phosphohygromycin using a phosphate moiety from ATP, resulting in the loss of its cell-killing activity. (Mus musculus) PubMed

 3095.

ErpA is an A-type Fe-S protein that is characterized by an essential role in cellular metabolism[ErpA] (Mus musculus) PubMed

 3096.

CNF1 contains two major binding regions for binding to laminin receptor precursor protein: one located within the N terminus, which contained amino acids 135 to 164, and one which resided in the C terminus and included amino acids 683 to 730. (Mus musculus) PubMed

 3097.

cytolethal distending toxin-1Phi is the latest member of a growing family of lambdoid phages encoding bacterial cyclomodulins [cytolethal distending toxin and type III effector protein] (Mus musculus) PubMed

 3098.

The results suggest that the excision event in E. coli may involve additional factors, such as RecA and that the physiological status can influence the excision of nifD element.[RecA] (Mus musculus) PubMed

 3099.

These data indicate that Pet secreted by EAEC binds to the cell surface via an unknown receptor, to be taken up by clathrin-mediated endocytosis, and exert its toxic effect in the cytoplasm. [Pet] (Mus musculus) PubMed

 3100.

The biological function of GlmZ is to positively control the glmS mRNA in response to GlcN-6-P concentrations and that YhbJ negatively regulates GlmZ. As in yhbJ mutants GlcN-6-P has no effect, YhbJ is essential for sensing this metabolite.[GlmZ] (Mus musculus) PubMed

 3101.

The steady-state kinetics and ligand binding properties of coaD in the biosynthesis of coenzyme A are reported.[CoA] (Mus musculus) PubMed

 3102.

Infection of mice with hph-expressing H. capsulatum yeast cells at sublethal doses resulted in lethality. (Mus musculus) PubMed

 3103.

Data show that ParM filaments have subunit-subunit interfaces that result in the helical handedness of the ParM filament being opposite to that of F-actin [ParM]. (Mus musculus) PubMed

 3104.

A stem-loop structure on the sblA transcript plays a negative role in the regulation of sblA expression and might be involved in the regulation of the specific degradation of the sblA transcript.[sblA] (Mus musculus) PubMed

 3105.

the NaK channel has a a Ca(2+) binding site at the extracellular entrance to the selectivity filter which allows Ca(2+) to act both as a permeating ion and blocker of CNG channels (Mus musculus) PubMed

 3106.

Data showed crystal structure of HpcH in the apo form, and with magnesium and the substrate analogue oxamate bound, to 1.6 A and 2.0 A [HpcH] (Mus musculus) PubMed

 3107.

analysis of the role of copper in folding and stability of cupredoxin-like copper-carrier protein CopC [CopC] (Mus musculus) PubMed

 3108.

We conclude that the Lon protease supports survival during anaerobic carbon starvation by a mechanism which does not depend on Clp.[Lon in strain SG1094] (Mus musculus) PubMed

 3109.

These findings suggest that the EspF-dependent assembly of SNX9 and N-WASP represents a novel form of signaling mimicry used to promote Escherichia coli pathogenesis and gastrointestinal disease.[EspF] (Mus musculus) PubMed

 3110.

the centromere-like parC DNA is wrapped around a ParR protein scaffold and works with ParM polymerization to drive active DNA transport during plasmid partition [parR, parM] (Mus musculus) PubMed

 3111.

The localized adherence pattern of an atypical enteropathogenic Escherichia coli is mediated by intimin encoded by the eae gene. [eae] (Mus musculus) PubMed

 3112.

analysis of the structural stability and dynamics of D-galactose/D-glucose-binding protein from Escherichia coli [GGBP] (Mus musculus) PubMed

 3113.

quantitative description of KcsA gating and of the macroscopic currents [KcsA] (Mus musculus) PubMed

 3114.

kinetic model is proposed to describe the gating events in KcsA that recapitulates its macroscopic and single-channel behavior [KcsA] (Mus musculus) PubMed

 3115.

analysis of the membrane-aqueous border for the voltage-sensing domain of potassium channel KvAP [KvAP] (Mus musculus) PubMed

 3116.

glycosylation is required to ensure a normal conformation of AIDA-I and may be only indirectly necessary for its cell-binding function.[AidA-I] (Mus musculus) PubMed

 3117.

a two-step reaction model mechanism is proposed, in which zinc-binding is regulated by the initial selective-binding of Zn(2+) to Cys followed by folding(Tim10) (Mus musculus) PubMed

 3118.

Immunoprecipitation experiments revealed that LeoA interacts directly with OmpA, but that the GTP-binding domain is non-essential for this interaction in ETEC. [LeoA, OmpA] (Mus musculus) PubMed

 3119.

phosphorescence of GlnBP is easily detected where emission of 2 tryptophan residues is readily discriminated by drastic difference in phosphorescence lifetime allowing assignments of short lifetime to W220 & long lifetime to W32[glutamine-binding protein] (Mus musculus) PubMed

 3120.

EspI modulates the virulence of attaching and effacing pathogens by binding host PDZ-domain proteins. (Mus musculus) PubMed

 3121.

This study showed that divergent transcription from a strong promoter can significantly enhance fooB expression and compensate for the absence of FooI in a wild-type strain.[FooB, FooI] (Mus musculus) PubMed

 3122.

dispersin's likely role in fimbrial function is to overcome electrostatic attraction between aggregative adherence fimbriae and the bacterial surface.[dispersin in strain ES66] (Mus musculus) PubMed

 3123.

Analysis of infrared polarized absorbance spectra and linear dichroism spectra of reconstituted melibiose permease from Escherichia coli [MelB] (Mus musculus) PubMed

 3124.

It was found that Tyr4, Trp5, Glu15, Tyr45, Tyr61, and Glu82 in MdtJ and Glu5, Glu19, Asp60, Trp68, and Trp81 in MdtI are involved in the speridine excretion activity of MdtJI. [MdtI] (Mus musculus) PubMed

 3125.

Structure discrimination for the C-terminal domain of Escherichia coli trigger factor in solution (Mus musculus) PubMed

 3126.

By atomic force microscopy, ParR molecules are shown to bind to each of the 5-fold repeated iterons of the plasmid R1 centromere-like site parC (parR). (Mus musculus) PubMed

 3127.

there is only a single high-affinity metalloid binding site in ArsA, and second that Cys-172 controls the affinity of this site for metalloid and hence the efficiency of metalloactivation of the ArsAB efflux pump (Mus musculus) PubMed

 3128.

the CpxAR stress response indirectly controls the synthesis of the F mating apparatus, a complex transenvelope type IV secretion system, by degrading TraJ via HslVU. [HslV and HslU] (Mus musculus) PubMed

 3129.

An "on-pathway" IM7 intermediate with nonnative interactions is formed as a consequence of an unusual cluster of highly frustrated interactions in the native structure; this cluster is involved in the binding of IM7 to its target, colicin E7. {IM7) (Mus musculus) PubMed

 3130.

These results imply that Rnase E plays a dual role in processing and degradation to achieve tight control of M1 RNA biosynthesis.[Rnase E] (Mus musculus) PubMed

 3131.

The expression of acid phytase (APPA)in transgenic soybeans and the metabolism of phytate to phosphorus are reported. (Mus musculus) PubMed

 3132.

analysis of barriers and barrierless folding in BBL [BBL] (Mus musculus) PubMed

 3133.

The contributions of HPF to 100S formation and translation were analysed in vitro.[HPF] (Mus musculus) PubMed

 3134.

beta-1,3-galactosyltransferase from E. coli O127 expresses a T-antigen mimic in the lipopolysaccharide (LPS) structure. glycosylates a series of GalNAc analogues with alpha-substitutions at the reducing end, including glycosylated Ser & Thr [WbiP] (Mus musculus) PubMed

 3135.

(PET, Escherichia coli) is expressed and shown to exhibit a 3-state folding and have a stable core structure. (Mus musculus) PubMed

 3136.

The IncH entry exclusion proteins EexA and EexB likely prevent redundant plasmid transfer by interaction with one another.[EexA, EexB] (Mus musculus) PubMed

 3137.

These results suggest that EspJ EspJ(EHEC) in phagocytes is sufficient to inhibit internalization of both IgG- and C3bi-opsonized RBC.[EspJ] (Mus musculus) PubMed

 3138.

the ability of S1 to recognize different RNAs results from a high adaptability of both its structure and its binding surface (Mus musculus) PubMed

 3139.

the molecular events coupled to ATP binding and hydrolysis (Mus musculus) PubMed

 3140.

Residue F180 of lactaldehyde dehydrogenase participates in the exclusion of NADP+ from the coenzyme binding site and disturbs the binding of NAD+ (lactaldehyde dehydrogenase). (Mus musculus) PubMed

 3141.

single-stranded DNA-binding protein functions to recruit polV to primer termini on RecA-coated DNA[Single-stranded DNA-binding protein] (Mus musculus) PubMed

 3142.

These results demonstrate that PepA requires specific DNA sequences for binding, and that PepA and ArgR have no direct role in Cre recombination at P1 loxP.[PepA, ArgR] (Mus musculus) PubMed

 3143.

This study investigated the role of the Cpx response in enteropathogenic Escherichia coli type III secretion through the locus of enterocyte effacement (LEE) pathogenicity island expression.[LEE] (Mus musculus) PubMed

 3144.

Gene opgB was reported to encode phosphoglycerol transferase I; in this study, it is demonstrated that the periplasmic phosphoglycerol transferase II is a soluble form of the membrane-bound phosphoglycerol transferase I. (Mus musculus) PubMed

 3145.

enzymatic properties of this lytic transglycosylase domain were found to be very similar to those of the wild-type enzyme[YfhD] (Mus musculus) PubMed

 3146.

The structure of a new ternary complex (FimC-FimF(t)-FimD(N)) with the subunit FimF(t) instead of FimH(p), is reported.[FimC, FimF, FimD] (Mus musculus) PubMed

 3147.

The crystal structure of the DapD tetrahydrodipicolinate N-succinyltransferase from Escherichia coli at 2.0 A resolution, is reported.[THDP N-succinyltransferase] (Mus musculus) PubMed

 3148.

AcpT overexpression also suppressed the lethality due to deletion of the entire yejM gene and this suppression also did not require that AcpT be enzymatically active.[AcpT, YejM] (Mus musculus) PubMed

 3149.

there is an orientation-dependent impediment to polymerase progression on 5'-CAG and 5'-CTG repeats that can be relieved by the binding of single-stranded DNA-binding protein [ssb] (Mus musculus) PubMed

 3150.

these data suggest that EtpA is required for optimal colonization of the intestine, findings paralleling those of previous in vitro studies demonstrating its role in adherence.[EtpA in strain H10407] (Mus musculus) PubMed

 3151.

results provide the structural basis for understanding the coupling between protein synthesis and enzymatic processing of nascent chains, and offer insights into the interplay of PDF with the ribosome-associated chaperone trigger factor [def =PDF] (Mus musculus) PubMed

 3152.

Thermal denaturation of penicillin acylase (PA) from Escherichia coli has been studied by high-sensitivity differential scanning calorimetry as a function of heating rate, pH and urea concentration.[Penicillin acylase] (Mus musculus) PubMed

 3153.

Electrochemistry measurements on DNA-modified electrodes are used to probe the effects of binding to DNA on the redox potential of SoxR, a transcription factor that contains a [2Fe-2S] cluster and is activated through oxidation.[SoxR] (Mus musculus) PubMed

 3154.

The role of glycine residues in EmrE, a small multidrug transporter from Escherichia coli, was studied.[EmrE] (Mus musculus) PubMed

 3155.

Osmotic induction of cardiolipin (CL) synthesis and concentration of ProP with CL at the cell poles adjust the osmotic activation threshold of ProP to match ambient conditions.[ProP] (Mus musculus) PubMed

 3156.

The phenotype of the arcA2 mutants was due to the presence of a creC constitutive mutation introduced by P1 transduction. (creC)(arcA2) (Mus musculus) PubMed

 3157.

Mutations in highly conserved residues at the active site affect the activity of the enzyme. Moreover, we have identified the residue that is responsible for setting the end product of RNase II [RNase II] (Mus musculus) PubMed

 3158.

secondary structure model of membrane-bound UbiA [UbiA] (Mus musculus) PubMed

 3159.

synergistic anion plays a structural and functional role in FbpA-mediated transport of iron across the periplasm and into the cytosol[FbpA] (Mus musculus) PubMed

 3160.

NfuA could act as a scaffold/chaperone for damaged Fe/S proteins (Mus musculus) PubMed

 3161.

observed partial release of trapped calcein following activation of MscL was attributed to the formation of a long-lived subconductance state of MscL following channel opening[ MscL] (Mus musculus) PubMed

 3162.

represents the first use of fluorescence approaches to estimate MsbA binding affinities for nucleotides and putative transport substrates[ MsbA] (Mus musculus) PubMed

 3163.

This study reveals hierarchical action of two well-conserved sRNAs in a complex regulatory cascade that controls the glmS mRNA.[glmS] (Mus musculus) PubMed

 3164.

The electron paramagnetic resonance results for ColA reconstituted into liposomes of E. coli lipids support the umbrella model for the closed channel state. (Colicin A) (Mus musculus) PubMed

 3165.

Therefore, L0017 is a chaperone, the second chaperone identified in this system after CesAB, and escorts EspA, a protein with a great tendency to polymerize.[L0017] (Mus musculus) PubMed

 3166.

colicin D treatment induce A-site mRNA cleavage in Escherichia coli along with amino acid starvation (Mus musculus) PubMed

 3167.

interaction of RecX protein and RecA may enable an enhanced DNA binding by RecX protein[SSB and RecA] (Mus musculus) PubMed

 3168.

The crystal structure of YdcF reveals a fold of the adenine nucleotide hydrolase-like family. YdcF binds S-adenosyl-L-methionine (AdoMet) with a Kd value of 25 M.[YdcF] (Mus musculus) PubMed

 3169.

A novel cell division factor ZapB was identified in Escherichia coli that simultaneously stimulates Z ring assembly and cell division. [ZapB] (Mus musculus) PubMed

 3170.

role of Mg(2+) is to overcome a kinetic barrier to melting of the DNA by RecBC and presumably also by RecBCD[RecBC] (Mus musculus) PubMed

 3171.

identify the residues involved directly in binding of substrate to the inward-facing conformation of GlpT, thus defining the structural basis for the substrate-specificity of this transporter[GlpT] (Mus musculus) PubMed

 3172.

tetracycline (Tc) plays the role of a specific Mg(2+) carrier, whereas the Mg(2+) ion itself makes key interactions that trigger the allosteric transition in the TetR:Tc complex[Tet repressor] (Mus musculus) PubMed

 3173.

During infection, iutA expression was increased 50-fold in the airsac and in the lung 3, 6 and 24h post infection; ibeA expression was increased 2.5-9-fold in the airsac in the early stages of the infection only. [ibeA, iutA] (Mus musculus) PubMed

 3174.

K48Q mutant of Escherichia coli Thymidylate synthase was studied using structural and biophysical methods.[Thymidylate synthase] (Mus musculus) PubMed

 3175.

combination of hydrophobic and hydrophilic binding surfaces explains the ability of ePepN to cleave Lys, Arg, Phe, and Tyr[ aminopeptidase N] (Mus musculus) PubMed

 3176.

FtsZ itself can assemble the Z ring and generate a force. No other proteins were needed for assembly and force generation. [FtsZ] (Mus musculus) PubMed

 3177.

F41A mutation increases the K(M) for UDP-3-O-(R-3-OHC14)-GlcN 30-fold, consistent with aromatic stacking of the corresponding F43 side chain against the uracil moiety of bound UDP-GlcNAc in the X-ray structure of Chlamydia trachomatis LpxD[LpxD] (Mus musculus) PubMed

 3178.

A conserved sequence-HRVW(279)QNRR--in delta subunit of gamma complex contributes to binding primer-template DNA (delta subunit of gamma complex). (Mus musculus) PubMed

 3179.

These results support the hypothesis that LT is a more significant contributor than STb to the virulence of F4(+) ETEC infections in young F4ac receptor-positive pigs less than 2 weeks old. [LT, STb] (Mus musculus) PubMed

 3180.

Crystal structure: AlkB uses an unprecedented base-flipping mechanism to access the damaged base (Mus musculus) PubMed

 3181.

complete enzyme models for the oxidized and reduced states of all three Fe-bound SOD species were generated using combined quantum mechanics/molecular mechanics (QM/MM) geometry optimizations[iron superoxide dismutase] (Mus musculus) PubMed

 3182.

Enteropathogenic Escherichia coli EspF was found to be responsible for decreased NHE3 activity; however, neither EspF-induced apoptosis nor the interaction of EspF with sorting nexin-9, an endocytic protein, were involved.[EspF] (Mus musculus) PubMed

 3183.

resulting model for C-terminal E. coli IF2 indicates important structural differences between the aIF5B crystal structure and IF2 in solution[ translation initiation factor IF2 ] (Mus musculus) PubMed

 3184.

Ionizable residues change their ionization state at acidic pH, thereby disrupting this network, modifying the electrostatic landscape near the channel gate, and favoring channel opening.[KcsA] (Mus musculus) PubMed

 3185.

The structure of the Escherichia coli 5-methyluridine (m(5)U) 54 tRNA methyltransferase (MTase) TrmA in a covalent complex with a 19-nt T arm analog to 2.4-A resolution.[TrmA] (Mus musculus) PubMed

 3186.

a surface type II beta-turn in the Escherichia coli protein EscU undergoes auto-cleavage by a mechanism involving cyclization of a strictly conserved asparagine residue; Structural analysis of SpaS [EscU; SpaS] (Mus musculus) PubMed

 3187.

nucleotide excision repair proteins from E. coli recognize the purine-Cr(III) adduct but not the Cr(III)-backbone phosphate complex[UvrA, B and C] (Mus musculus) PubMed

 3188.

analysis of nucleotide regulation of aspartate transcarbamoylase [ATCase] (Mus musculus) PubMed

 3189.

conformational change of the insertase YidC upon biing a Pf3 coat protein molecule (YidC). (Mus musculus) PubMed

 3190.

binding of misfolded proteins transforms hexameric DegP into large, catalytically active 12-meric and 24-meric multimers [DegP] (Mus musculus) PubMed

 3191.

discussion of the principally different mechanisms of ribosome splitting by IF1/IF3 and by RRF/EF-G [initiation factor 1 and ribosome recycling factor] (Mus musculus) PubMed

 3192.

The first crystal structure of a bacterial PTK, the C-terminal kinase domain of Escherichia coli Tyr kinase (Etk) at 2.5-A resolution, is reported.[Etk] (Mus musculus) PubMed

 3193.

crystal structures of the Escherichia coli RecA-ssDNA and RecA-heteroduplex filaments [RecA] (Mus musculus) PubMed

 3194.

19 ciprofloxacin-resistant clinical isolates of K. pneumoniae in pediatric patients in China were positive for the qnr gene [quinolone resistance gene /qnr gene] (Mus musculus) PubMed

 3195.

The enhanced affinity for the operator element is mediated by a cooperative DNA binding by a pair of RelB dimers and that the interaction between RelB dimers is strongly augmented by the presence of the cognate toxin RelE.[RelB, RelE] (Mus musculus) PubMed

 3196.

The slow kinetics of holoBirA dimerization combined with fluctuations in the intracellular apoBCCP pool are critical determinants in partitioning BirA between its distinct biological functions.[BirA] (Mus musculus) PubMed

 3197.

stoichiometry of the subunit c rings remains constant even after reduction of the synthesis of subunit c[ATP synthase subunit c] (Mus musculus) PubMed

 3198.

These results suggest that Stx2-induced apoptosis is mediated by CHOP in human brain microvascular endothelial cells (HBMEC) and involves activation of both the intrinsic and extrinsic pathways of apoptosis. (Mus musculus) PubMed

 3199.

The results indicate that Asp142 and Asp447, located on the A1 and A2 halves of the protein, have different roles in ArsA catalysis, consistent with our proposal that these two halves are functionally nonequivalent.[ArsA] (Mus musculus) PubMed

 3200.

The authors found that EspF from rabbit enteropathogenic Escherichia coli (E22) participates in the regulation of actin polymerization by binding to a complex of proteins at the tight junctions.[EspF] (Mus musculus) PubMed

 3201.

The authors found that DraE-positive recombinant bacteria adhere to and are internalized by primary human bladder epithelial cells which express DAF and CEACAMs.[DraE] (Mus musculus) PubMed

 3202.

An EAL domain protein, encoded by ydiV, and cAMP are involved in the interaction between the two Quorum sensing systems in E. coli.[ydiV] (Mus musculus) PubMed

 3203.

YgjK is a glucosidase with relaxed specificity for sugars[YgjK] (Mus musculus) PubMed

 3204.

Analysis of the amino acid sequences of subunits NuoM and NuoN in the membrane domain of Complex I revealed a clear common pattern, including two lysines that are predicted to be located within the membrane, important for quinone reductase activity.[NuoM] (Mus musculus) PubMed

 3205.

The DeltaibeA mutant was less adhesive to human brain microvascular endothelial cells than the wild-type strain BEN2908 was.[IbeA] (Mus musculus) PubMed

 3206.

These studies identify a correlation between the stability of the ExoI/SSB-C terminal complex and SSB-stimulation of ExoI activity.[Exo I, SSB] (Mus musculus) PubMed

 3207.

Analysis of ATP substrate inhibition kinetics on ATP hydrolysis in hexameric PspF(1-275) indicates negative homotropic effects between subunits[PspF] (Mus musculus) PubMed

 3208.

Presented is the first high pH structure of Escherichia coli aspartate transcarbamoylase;Alterations in the electropositive environment of the active site may be responsible for the enhanced activity of the enzyme at pH 8.5. (Mus musculus) PubMed

 3209.

Our results indicate that LamB, OmpC and TolC are important OM proteins for tetracycline resistance in E. coli. [LamB, OmpC, TolC] (Mus musculus) PubMed

 3210.

The regulation of the activity of quinolinate synthase (NadA) via disulfide bond formation between Cys291 and Cys294 is reported.[NadA] (Mus musculus) PubMed

 3211.

The Asn378 residue of E. coli photolyase is crucial both for stabilizing the neutral flavin radical cofactor and for catalysis.[DNA photolyase] (Mus musculus) PubMed

 3212.

Our results show that the acyltransferases that generate the secondary acyl chains of lipid A are members of the GPAT family and set the stage for structural studies.[LpxL] (Mus musculus) PubMed

 3213.

REVIEW: mechanisms of YidC substrate recognition and membrane insertion with emphasis on its role in the assembly of multimeric membrane protein complexes such as the F1F0-ATP synthase [YidC] (Mus musculus) PubMed

 3214.

Characterization of three independent intragenic second-site suppressors of the rne-1 and rne-3071 alleles that demonstrate the dissociation of the in vivo activity of RNase E on mRNA versus tRNA and rRNA substrates (RNase E). (Mus musculus) PubMed

 3215.

Demonstration that biotin synthase catalyzes the stepwise addition of sulfur to dethiobiotin (biotin synthase). (Mus musculus) PubMed

 3216.

an alternative proton pathway in E. coli succinate dehydrogenase that might be functional only in vitro (succinate dehydrogenase). (Mus musculus) PubMed

 3217.

both DegP oligomers were also observed in extracts of E. coli cells, strongly implicating their physiological importance[ DegP ] (Mus musculus) PubMed

 3218.

Polarity of helicase and fork arrest in vitro is generated by a mechanism that not only involves interaction between the terminator protein and the arrested enzyme but also of Tus with replication termini.[DnaB, Tus] (Mus musculus) PubMed

 3219.

Site-directed spin labeling electron paramagnetic resonance spectroscopy was used to study the opening and closing of the nucleotide-binding interface of MalFGK(2) during the catalytic cycle.[MBP, MalFGK(2)] (Mus musculus) PubMed

 3220.

An uneven binding of MinD to the heterogeneous native membrane is possible, leading to formation of a lipid-specific distribution pattern of MinD and/or modulation of its temporal behavior.[MinD] (Mus musculus) PubMed

 3221.

the X-ray crystal structure of Escherichia coli regulator of nucleoside kinase (Rnk) at 1.9 (Mus musculus) PubMed

 3222.

Changes in dynamics of a model membrane caused by MinD binding was studied using membrane-embedded fluorescent probes as reporters.[MinD] (Mus musculus) PubMed

 3223.

The crystal structure of K4CP in the presence of UDP and UDP-GalNAc as well as with UDP and UDP-GlcUA was determined. (K4CP, chondroitin polymerase) (Mus musculus) PubMed

 3224.

expression of FkpA-DsbAs conferred modest resistance to CuCl2, a phenotype that depends on disulfide bond isomerization[DsbC] (Mus musculus) PubMed

 3225.

These results indicate that MacAB, an ATP-binding cassette transporter of MacB and its accessory protein, MacA, participates in the translocation of STII from the periplasm to the exterior. [MacAB] (Mus musculus) PubMed

 3226.

analysis of chondroitin polymerase K4CP and the molecular mechanism of selective bindings of donor substrates to two active sites [K4CP] (Mus musculus) PubMed

 3227.

These results are consistent with a role for BipA in either the structure or the function of the ribosome and imply that wild-type ribosomes are dependent on BipA for efficient expression of target messenger RNAs.[BipA] (Mus musculus) PubMed

 3228.

activity of cytochrome bo(3) with long-chain ubiquinones appears to be different from previous reports using short-chain substrate analogues such as ubiquinol(UQ)-1 in that typical Michaelis-Menten kinetics are not observed using UQ-10[cytochrome bo3 ] (Mus musculus) PubMed

 3229.

tRNase Z might help modulate a cell growth rate by repressing translation under some stressful conditions. (Mus musculus) PubMed

 3230.

ClpA becomes largely resistant to autodegradation in the absence of its C-terminus and, conversely, transfer of the last 11 residues of ClpA to the C-terminus of green fluorescent protein (GFP) renders GFP a substrate of ClpAP.[ClpA, ClpP] (Mus musculus) PubMed

 3231.

An alternative approach was applied to study the catalytic mechanism of alkaline phosphatase (AP), a widely studied prototypical bimetallo enzyme.[Alklaine phosphatase] (Mus musculus) PubMed

 3232.

the involvement of external Ca2+ on cPHB synthesis regulated by the AtoS-AtoC two-component system, thus linking Ca2+ with a signal transduction system, most probably through a transporter. (Mus musculus) PubMed

 3233.

the first kinetic characterization of the reaction between NO and iron-sulfur clusters in protein using the Escherichia coli IlvD (dihydroxyacid dehydratase) [4Fe-4S] cluster as an example (Mus musculus) PubMed

 3234.

histidine 63 of MetAP-I affects the hydrolysis of small peptide substrates whereas large peptides can overcome the observed loss in binding energy, as predicted from K(m) values, by additional hydrophilic and hydrophobic interactions [MetAP-I] (Mus musculus) PubMed

 3235.

The DNA translocation properties of EcoR124I complexes in which the HsdR subunits had been mutated in the RecB-like nuclease motif II or III, were examined.[EcoR124I] (Mus musculus) PubMed

 3236.

Taken together, these results pinpoint three amino acids in CNF1 that are key amino acids for recognition by neutralizing MAb NG8 and further help define a region in CNF1 that is critical for full toxin binding to HEp-2 cells.[Cnf1] (Mus musculus) PubMed

 3237.

MacA would facilitate the delivery of drugs by MacB to TolC by enhancing the binding of drugs to it and inducing a conformation of MacB that is primed and competent for binding TolC[MacB and MacA] (Mus musculus) PubMed

 3238.

findings show Tir & EspF(U) are sufficient for actin pedestal formation in cells; EspF(U) repeats activate a protein complex containing N-WASP & WIP in vitro, suggesting the repeats cooperate to stimulate actin polymerization in vivo [EspF(U)] (Mus musculus) PubMed

 3239.

we confirm by direct measurements of Cl- and H+ fluxes a Cl--to-H+ exchange stoichiometry of 2, and summarize experimental facts pertinent to the exchange mechanism [CLC-ec1] (Mus musculus) PubMed

 3240.

The medium-resolution structure of MenD from Escherichia coli (EcMenD) in complex with its cofactor and Mn2+ has been determined in two related hexagonal crystal forms.[MenD] (Mus musculus) PubMed

 3241.

The 2'-OH of A76 of tRNA(Thr) and a conserved active-site histidine (His-309) collaborate to catalyze aminoacyl transfer by a mechanism distinct from HisRS.[ThrRS] (Mus musculus) PubMed

 3242.

The distribution in the F(O)F(1) structure of compliant and stiff domains, was investigated.[F0F1ATPase] (Mus musculus) PubMed

 3243.

Skp does not only serve as a specialized chaperone for a small set of outer membrane proteins, but it seems to exhibit a broader substrate spectrum, including soluble periplasmic proteins.[Skp] (Mus musculus) PubMed

 3244.

crystal structures also provide detailed insights into the mechanism of carbon-mercury bond cleavage by MerB[MerB] (Mus musculus) PubMed

 3245.

ppGpp/DksA responsive sigma(54)-transcription in the environmentally adaptable P. putida was found to be more robust under low energy conditions that occur upon nutrient depletion[RNA Polymerase Sigma 54 and DksA] (Mus musculus) PubMed

 3246.

Analysis on substrate specificity of Escherichia coli ribonuclease P using shape variants of pre-tRNA: proposal of subsites model for substrate shape recognition (ribonuclease P). (Mus musculus) PubMed

 3247.

Cells lacking rodZ no longer had rod shape but rather were round or oval. (Mus musculus) PubMed

 3248.

Four loop-forming sections of the chain were probed for the time course of loop formation during refolding of Escherichia coli adenylate kinase.[Adenylate kinase] (Mus musculus) PubMed

 3249.

DraE or AfaE-III adhesin subunits are necessary and sufficient to promote the receptor-mediated bacterial internalization into epithelial cells expressing human decay-accelerating factor (DAF), CEACAM1, CEA, or CEACAM6.[DraE & AfaE-III] (Mus musculus) PubMed

 3250.

The authors show that clustering transfers Tir into cholesterol-rich detergent-resistant microdomains (DRMs), a signal prompting transient c-Fyn accumulation at bacterial adhesion sites.[Tir] (Mus musculus) PubMed

 3251.

Hma is a high-affinity receptor for heme, and heme uptake is required by uropathogenic Escherichia coli for kidney infection. [Hma] (Mus musculus) PubMed

 3252.

Fcf1 and Fcf2 from E. coli O52 were expressed, purified and assayed for their respective activities. (Fcf1) (Fcf2) (Mus musculus) PubMed

 3253.

The one-electron activation of the cluster, coupled to catalytic recycling of the superoxide anion back to oxygen via superoxide dismutase and catalase, provides a novel means of amplifying the sensitivity of [4Fe-4S](2+) FNR to its signal molecule.[FNR] (Mus musculus) PubMed

 3254.

The ability of SecB-bound substrates to continue folding while bound to SecB and their ability to interact with other components of the secretory machinery may be key opposing determinants that inhibit and promote protein export, respectively.[SecB] (Mus musculus) PubMed

 3255.

The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate. (Mus musculus) PubMed

 3256.

Structure of a xenon derivative of Escherichia coli copper amine oxidase: confirmation of the proposed oxygen-entry pathway (Mus musculus) PubMed

 3257.

Thiol peroxidase (Tpx) forms a mixed-disulfide complex with cytoplasmic thioredoxin 1 (Trx1), indicating that Tpx localizes in the cytoplasm. [Tpx] (Mus musculus) PubMed

 3258.

The characterization of the HicA protein as a member of a multigene toxin-antitoxin gene family is reported.[HicA] (Mus musculus) PubMed

 3259.

The role of five toxin-antitoxin systems in E. Coli were evaluated, including the role of YjgK.[YjgK] (Mus musculus) PubMed

 3260.

EtpA, a TPS exoprotein adhesin of enterotoxigenic E. coli, mimics and interacts with highly conserved regions of flagellin, the major subunit of flagella, and that these interactions are critical for adherence and intestinal colonization [EtpA] (Mus musculus) PubMed

 3261.

These data support a conserved three-state chaperone cycle where the conformational equilibrium varies between species, implicating evolutionary tuning to meet the particular client protein and metabolic environment of an organism.[HtpG] (Mus musculus) PubMed

 3262.

the redox potential of thioredoxin 2, the pK(a) of the active site nucleophilic cysteine, as well as the stability of the oxidized and reduced form of the protein (Mus musculus) PubMed

 3263.

This study present results showing that the leucine-responsive regulatory protein, Lrp, is involved in this phenotype by acting as a positive regulator of YojI, a chromosomally encoded efflux pump which expels microcin out of cells.[Lrp; YojI] (Mus musculus) PubMed

 3264.

This study suggested that iron-dependent regulation of FimE via IscR leads to decreased surface attachment and biofilm dispersal under iron-limiting conditions.[IscR; FimE] (Mus musculus) PubMed

 3265.

The role of cAMP receptor in the expression of heat-labile toxin in enterotoxigenic E. coli was studied.[LT-I] (Mus musculus) PubMed

 3266.

Loss of RodZ leads to misassembly of MreB into non-spiral structures, and a consequent loss of cell shape.[MreB, RodZ] (Mus musculus) PubMed

 3267.

ParM filaments were identified in E.coli; small bundles of three to five intracellular ParM filaments that were situated close to the edge of the nucleoid were observed (Mus musculus) PubMed

 3268.

Distinct activities of Escherichia coli small heat shock proteins IbpA and IbpB promote efficient protein disaggregation (Mus musculus) PubMed

 3269.

These data demonstrate that S10 and NusB together form a BoxA-binding module, that NusB facilitates entry of S10 into the transcription machinery, and that S10 represents a central hub in processive antitermination.[NusB, NusE] (Mus musculus) PubMed

 3270.

CycA mRNA is a target for both GcvB and Hfq regulation. [CycA, Hfq] (Mus musculus) PubMed

 3271.

HfQ-GcvB interaction is necessary for GcvB mediated regulation of OppA and DppA and to facilitate RNA-RNA pairing of GvcB with its target mRNAs. [Hfq, OppA, OppB] (Mus musculus) PubMed

 3272.

Two mechanisms by which the hot dog-fold thioesterase EntH can potentially prevent or reverse EntB misacylation, are shown.[EntH] (Mus musculus) PubMed

 3273.

GTP hydrolysis on EF-Tu is controlled through a hydrophobic gate mechanism.[EF-Tu] (Mus musculus) PubMed

 3274.

structures of gp23-chaperonin complexes, showing both the initial captured state and the final, close-to-native state with gp23 encapsulated in the folding chamber [GroEL] (Mus musculus) PubMed

 3275.

We have identified and characterized a novel TTSS-dependent effector protein (Ibe) of EPEC and EHEC strains that interacts with the host cell scaffolding protein, IQGAP1. [Ibe] (Mus musculus) PubMed

 3276.

These data establish the specific structural features of this noncatalytic domain of TraI that are essential to DNA conjugation. (Mus musculus) PubMed

 3277.

YmdB functions by interacting with a site in the RNase III catalytic region, that expression of YmdB is transcriptionally activated by both cold-shock stress and the entry of cells into stationary phase [YmdB and RNase III; substrain not found] (Mus musculus) PubMed

 3278.

The antibiotic resistance conferred by Cfr is provided by methylation at the 8 position and is independent of methylation at the 2 position of A2503 of 23S rRNA. (Mus musculus) PubMed

 3279.

DegS stimulation can be regulated by outer-membrane porins peptide affinity for the active and for the inactive protease conformations, as well as by preferential substrate binding to active DegS.[DegS] (Mus musculus) PubMed

 3280.

An liquid chromatography-mass spectrometry study revealed some heterogeneity in terms of molecular mass of a cysteine-free mutant of dihydrofolate reductase (DHFR) after long storage of the highly purified protein as an ammonium sulfate precipitate.[DHFR] (Mus musculus) PubMed

 3281.

The active domain of colicin E5 (E5-CRD) was expressed in Saccharomyces cerevisiae and its effects on growth, was investigated.[Colicin E5] (Mus musculus) PubMed

 3282.

The membrane-bound closed channel structure of helices 4 and 5 (Lys-406-Asp-446) of the colicin E1 channel domain was investigated by using a site-directed fluorescence labeling technique.[Colicin E1] (Mus musculus) PubMed

 3283.

the bacterial actin homolog MreB participates in the temporal oscillation of Topo IV activity (Mus musculus) PubMed

 3284.

Here, the authors show that an approximately 55-kDa fragment of CNF1, which contains the catalytic domain and an additional part of the toxin, is present in the cytosol.[Cnf1] (Mus musculus) PubMed

 3285.

YcgF does not degrade the signaling molecule c-di-GMP, but directly binds to and releases the MerR-like repressor YcgE from its operator DNA upon blue-light irradiation [ycfF] (Mus musculus) PubMed

 3286.

The authors identified a region in the the heat-labile enterotoxin LT distinct from the pocket involved in eukaryotic receptor binding that is responsible for binding to the surface of E. coli. (Mus musculus) PubMed

 3287.

findings indicate that a single cleft in the beta sliding clamp is sufficient for both loading and stimulation of Pol III replication, but both clefts are required for unloading clamp from DNA after replication is completed (beta sliding clamp). (Mus musculus) PubMed

 3288.

The authors show that IRSp53 family members, key regulators of membrane and actin dynamics, directly interact with both Tir and EspF(U). (Mus musculus) PubMed

 3289.

Structural and biochemical analyses revealed that the E. coli YrdC protein binds ATP and preferentially binds RNA(Thr) lacking only the threonylcarbamoyladenosine modification. (Mus musculus) PubMed

 3290.

NMR structures of a mutant of E. coli RelE toxin, RelE(R81A/R83A), with reduced toxicity and its complex with an inhibitory peptide from RelB antitoxin, RelB(C) (Lys(47)-Leu(79)), have been determined.[RelE, RelB] (Mus musculus) PubMed

 3291.

The mechanism of the four-electron reduction of dioxygen by a multicopper oxidase, CueO, was studied based on reactions of single and double mutants with Cys(500), a type I copper ligand, and the noncoordinating Asp(112) and Glu(506). [CueO] (Mus musculus) PubMed

 3292.

A previously characterized hypermorphic mutant FtsA (FtsA*) partially disassembled FtsZ polymers in vitro.[FtsA, FtsZ] (Mus musculus) PubMed

 3293.

studies suggested that the ibeR gene was involved in regulating stationary-phase gene expression related to stress resistance and pathogenesis [IbeR] (Mus musculus) PubMed

 3294.

The solution nuclear magnetic resonance structure of a truncated version of SlyD (1-165) from Escherichia coli (SlyD*) that lacks the presumably unstructured C-terminal tail, was determined.[SlyD] (Mus musculus) PubMed

 3295.

lipid insertion instigates a global conformational change in colicin Ia and more than one molecule participates in the channel architecture with the vestibule, possibly facilitating the large scale peptide translocation upon channel opening[COLICIN IA] (Mus musculus) PubMed

 3296.

YihU is a novel gamma-hydroxybutyrate dehydrogenase involved in the metabolism of succinic semialdehyde, and other potentially toxic intermediates that may accumulate under stress conditions in E. coli[YIHU] (Mus musculus) PubMed

 3297.

Bundlin contains an N-acetyllactosamine-specific carbohydrate-binding domain. [bundlin] (Mus musculus) PubMed

 3298.

In this work, four single tryptophan (Trp) mutants of the dimeric mannitol transporter of Escherichia coli, EII(mtl), are characterized using Trp and 5-fluoroTrp (5-FTrp) fluorescence spectroscopy (Mus musculus) PubMed

 3299.

Two substitutions in DksA, L15F and N88I, result in higher DksA activity both in vivo and in vitro, primarily by increasing the apparent affinity of DksA for RNA polymerase.[DksA] (Mus musculus) PubMed

 3300.

MzrA is a type II membrane protein that specifically interacts with EnvZ but not with OmpR or the related membrane sensor kinase, CpxA. [MzrA] (Mus musculus) PubMed

 3301.

Here, we report the crystal structure of the C-terminal nuclease domain of RecE at 2.8 A resolution (Mus musculus) PubMed

 3302.

SecY channel loosely sealed, or with a plug locked open, does not, however, lead to general membrane permeability.[SecY] (Mus musculus) PubMed

 3303.

The results support an alternating site model for catalysis in HisRS that may prove to be common to other class II aminoacyl-tRNA synthetases.[HisRS] (Mus musculus) PubMed

 3304.

Subunit a of the F(1)F(0) ATP synthase (F(0)a) is strictly dependent on Ffh, SecYEG and YidC for its membrane insertion but independent of the proton motive force.[YidC, SecYEG, F0a] (Mus musculus) PubMed

 3305.

The effect of the initial binding process was examined in vitro by fluorescence quenching of the tryptophan (Trp) residues of YidC which are highly sensitive fluorescent probes for changes of the protein's tertiary structure.[YidC] (Mus musculus) PubMed

 3306.

The structure of three secondary transporter proteins, GltT of Bacillus stearothermophilus, CitS of Klebsiella pneumoniae, and GltS of Escherichia coli, was studied.[GltS] (Mus musculus) PubMed

 3307.

Three aspects of FtsZ filament dynamics at steady state: rates of GTP hydrolysis, subunit exchange between protofilaments, and disassembly induced by dilution or excess GDP, were measured.[FtsZ] (Mus musculus) PubMed

 3308.

Because the binding of 3-isopropylmalate(IPM)to 3-isopropylmalate dehydrogenase (IPMDH) is associated with a hinge-bending domain closure, the more intense hinge-bending fluctuations at higher temperatures increasingly interfere with IPM binding[IPMDH] (Mus musculus) PubMed

 3309.

The prevalence of espM and espT in enteropathogenic and enteroemhorrhagic Escherichia coli strains isolated from humans is reported.[espM; espT] (Mus musculus) PubMed

 3310.

The effects of synthetic signal peptides, wild-type (WT) and export-defective mutant (MT) of ribose-binding protein, on the conformational changes of signal recognition particle 54 homologue (Ffh) in Escherichia coli, was examined.[Ffh, RbsB] (Mus musculus) PubMed

 3311.

The crystallographic results and the lack of functional cysteine residues in the active site of YfcG suggests that the reductase activity is unique in that no sulfhydryl groups in the YfcG protein are covalently involved in the redox chemistry.[YfcG] (Mus musculus) PubMed

 3312.

A beta1,3-galactosyltransferase (WbgO) was identified in Escherichia coli O55:H7; WbgO requires a divalent metal ion, either Mn(2+) or Mg(2+), for its activity. [beta1,3-galactosyltransferase (WbgO)] (Mus musculus) PubMed

 3313.

preliminary Xray structure [CusB] (Mus musculus) PubMed

 3314.

cglD deletion in E. coli K1 leads to prolonged survival of neonatal rats in experimental meningitis, without affecting the penetration of E. coli K1 through the blood-brain barrier. [CglD] (Mus musculus) PubMed

 3315.

Outer membrane protein A (OmpA) inhibits cellulose production through the CpxRA stress response system, and this reduction in cellulose increases biofilm formation on hydrophobic surfaces. [OmpA/CpxR/CpxA/E.coli K12 BW25113] (Mus musculus) PubMed

 3316.

active form of DNA polymerase V is UmuD'(2)C-RecA-ATP [umuD, umuC & recA] (Mus musculus) PubMed

 3317.

Folding via a three-helical species stabilised by both native and non-native interactions is an essential feature of Im7 folding, independent of the helical propensity of helix III.[colicin e7 immunity protein Im7] (Mus musculus) PubMed

 3318.

Activation of SoxR can occur in a DNA-mediated reaction with guanine radicals, an early genomic signal of oxidative stress, serving as the oxidant.[SoxR] (Mus musculus) PubMed

 3319.

Substrate molecules bind on the periphery of the TatBC complex and that substrate binding causes a significant reduction in diameter of the TatBC part of the complex.TatB, TatC] (Mus musculus) PubMed

 3320.

katP contributes to the complex gene network protecting E. coli strain 43895 from peroxide-mediated oxidative damage in an OxyR-dependent manner. [katP] (Mus musculus) PubMed

 3321.

The cloning and characterization of a new class 1 integron carrying an ISCR1 element in E. coli clinical strains harboring the blaCMY-11 gene are reported.[blaCMY-11; ISCR1] (Mus musculus) PubMed

 3322.

The allelic variations of eae, bfpA, and perA proteins in typical and atypical E. coli in a cohort of Peruvian children with diarrhea are reported.[eae] (Mus musculus) PubMed

 3323.

overall rate-limiting step of the enzymatic reaction seems to be the release of Fpg from its adduct with the 4-oxo-2-pentenal remnant of the deoxyribose moiety formed as a result of DNA strand cleavage by beta,delta-elmination [fpg] (Mus musculus) PubMed

 3324.

The first crystallographic model of the MukB hinge domain, is reported.[MukB] (Mus musculus) PubMed

 3325.

dissociation of product RNA from tRNA-guanine transglycosylase is overall rate-limiting in the steady state [TGT] (Mus musculus) PubMed

 3326.

Transmission electron microscopy reveals the accumulation of aberrant intracellular membranes when LpxB is overexpressed [LpxB] (Mus musculus) PubMed

 3327.

important regulatory component of the cascade that governs the expression of LEE operons and the resulting ability of EHEC O157:H7 to intimately adhere to host cells.[Hha] (Mus musculus) PubMed

 3328.

StcE protease contributes to intimate adherence of EHEC to host cells by cleavage of glycoproteins from the cell surface [StcE protease] (Mus musculus) PubMed

 3329.

The effects of ClpXP on the type III protein secretion system through regulation of RpoS and GrlR in EHEC 0157 is reported. [GrlR] (Mus musculus) PubMed

 3330.

These results show that that quorum sensing regulators B and C (QseBC) are transcribed in an operon, and that QseB may act to autoregulate its own transcription through binding to low- and high-affinity sites found in its promoter [qseB,C]. (Mus musculus) PubMed

 3331.

NleC is translocated into host cells via enterocyte effacement-encoded type III secretion system. (NleC) NleD is translocated into host cells via enterocyte effacement-encoded type III secretion system. (NleD) (Mus musculus) PubMed

 3332.

GrlA-dependent repression of the flagellar regulon is important for efficient cell adhesion of EHEC to host cells [GrlA] (Mus musculus) PubMed

 3333.

Ehx levels were not induced in the grlR grlA double mutant strain but increased markedly by overexpression of GrlA even in the ler mutant, indicating that GrlA is responsible for this regulation.[GrlA] (Mus musculus) PubMed

 3334.

EspL2 of E. coli O157:H7 Sakai bound F-actin-aggregating annexin 2 directly, increasing its activity.[EspL2] (Mus musculus) PubMed

 3335.

GadE is critical for the acid resistance and plays an role in virulence. [GadE] (Mus musculus) PubMed

 3336.

The authors demonstrated that the association between the enterohemorrhagic Escherichia coli O157:H7 EspFu and IRSp53 induces dynamic membrane remodeling in epithelial cells.[ EspFu] (Mus musculus) PubMed

 3337.

it is demonstrated that NikR can regulate H. pylori nickel metabolism by directly controlling transcriptional repression of NixA-mediated nickel uptake and transcriptional induction of urease expression.[NikR] (Mus musculus) PubMed

 3338.

detailed comparison of the quinol:fumarate reductase enzymes from C. jejuni and H. pylori with that of W. succinogenes [QFR] (Mus musculus) PubMed

 3339.

Virulence factor CagA induces human gastric epithelial cell (GEC) production of macrophage migration inhibitory factor that in turn up-regulates procarcinogenic GEC events. [CagA] (Mus musculus) PubMed

 3340.

CznABC metal export functions of H. pylori are essential for gastric colonization and underline the extraordinary importance of metal ion homeostasis for survival of H. pylori in the gastric environment. (CznA, CznB, CznC) (Mus musculus) PubMed

 3341.

The participation of a cluster consisting of surface-exposed histidines is not present in this protein in Helicobacter pylori. {nikR] (Mus musculus) PubMed

 3342.

H. pylori NikR controls nickel-responsive expression of the HP1400 (FecA3) and HP1512 (FrpB4) OMPs. (NikR) (Mus musculus) PubMed

 3343.

studies indicate that high levels of AhpC are not required for in vitro growth or for primary gastric colonization.[AhpC] (Mus musculus) PubMed

 3344.

An extreme carboxy terminal region and an adjacent unique 34 amino acid insertion region were found to be essential for DnaB helicase activity (DnaB helicase). (Mus musculus) PubMed

 3345.

This study provided the first evidences that the single cysteine residue of HpPPase (Helicobacter pylori inorganic pyrophosphatase) was involved in enzyme activation, thermostability, and stabilization of quaternary structure. [HpPPase] (Mus musculus) PubMed

 3346.

Phe181Pro mutation within the alpha7-beta8 loop disrupts the hexamerization of Quinolinic acid phosphoribosyltransferase, and the resultant dimer shows dramatically reduced protein stability and no activity (Quinolinic acid phosphoribosyltransferase). (Mus musculus) PubMed

 3347.

Our data indicate that CagF binding precedes recognition of the C-terminal CagA translocation signal, and that both steps are required to recruit CagA to the type IV translocation channel.[CagF, CagA] (Mus musculus) PubMed

 3348.

Characterization of a waaF mutant of Helicobacter pylori strain 26695 provides evidence that an extended lipopolysaccharide structure has a limited role in the invasion of gastric cancer cells (Mus musculus) PubMed

 3349.

Carbonic anhydrases (alpha and beta) contribute to the urease-dependent response to acidity of H. pylori and are required for high-grade inflammation and efficient colonization by some strains.[alpha carbonic anhydrase, beta carbonic anhydrase] (Mus musculus) PubMed

 3350.

TlpD was found to mediate a repellent tactic response away from conditions of reduced electron transport.(TlpD) (Mus musculus) PubMed

 3351.

These results suggest that delivery of CagA into epithelial cells by the bacterial type IV secretion system is mediated in a cholesterol-dependent manner. (Mus musculus) PubMed

 3352.

Aldo-keto reductase reduces a range of aromatic aldehyde substrates with high catalytic efficiency, and exhibits dual cofactor specificity for both NADPH and NADH (Aldo-keto reductase). (Mus musculus) PubMed

 3353.

AddAB and RecA are required for efficient colonization of the stomach of mice, RecA more than AddAB.(AddA) (Mus musculus) PubMed

 3354.

Inactivation of the arsS (HP0165)and arsR results in a 10-fold SabA-dependent(HP0725) increase in adherence to gastric epithelial cells in strain J99 but not in strain 26695.[ArsR] (Mus musculus) PubMed

 3355.

Biochemical and genetic analyses of restriction endonuclease and a DNA methyltransferase activity encoded by the locus HP0502/0503/0504/0505 (HP0502/0503/0504/0505). (Mus musculus) PubMed

 3356.

Helicobacter pylori (Hp) SSB bound specifically to ssDNA and modulated the enzymatic ATPase and helicase activity of HpDnaB helicase[Dnab and single-stranded DNA binding protein] (Mus musculus) PubMed

 3357.

Thus, nonphosphorylated CagA activity contributes to the epithelial proliferative and proinflammatory responses associated with development of chronic gastritis and gastric cancer.[CagA] (Mus musculus) PubMed

 3358.

The Helicobacter pylory single-stranded DNA (ssDNA)-binding protein (SSB) monomer folds as an oligonucleotide/oligosaccharide binding fold with a Y-shaped conformation. (Mus musculus) PubMed

 3359.

Effect of FliK mutation on the transcriptional activity of the {sigma}54 sigma factor RpoN in H pylori. FliK appears to be involved in three processes: hook-length control, export substrate specificity and control of RpoN transcriptional activity. [FliK] (Mus musculus) PubMed

 3360.

The results indicate that function of ORF390 in WSSV is a kind of apoptotic suppressor (ORF390) (Mus musculus) PubMed

 3361.

identified VP664 as major structural protein that forms stacked rings in nucleocapsid [VP664] (Mus musculus) PubMed

 3362.

vp15 functions as histone-like DNA-binding protein with preference to supercoiled DNA suggesting it is involved in the packaging of the WSSV genome in the nucleocapsid. [VP15] (Mus musculus) PubMed

 3363.

VP31 might play an important role in infectivity of this virus [VP31] (Mus musculus) PubMed

 3364.

nonstructural protein VP9 has been identified and expressed in Escherichia coli, purified and crystallized (VP9 nonstructural protein) (Mus musculus) PubMed

 3365.

The crystal structure of VP9 revealed a ferredoxin fold with divalent metal ion binding sites. (VP9) (Mus musculus) PubMed

 3366.

an analysis of VP51 AND VP76 proteins in this virus[VP51 AND VP76] (Mus musculus) PubMed

 3367.

VP37 interacted with VP28 and VP26 [vp37] (Mus musculus) PubMed

 3368.

data suggest that a complex involving SsaM and SpiC distinguishes between translocators and effector proteins, and controls their ordered secretion through the pathogenicity island 2 type III secretion system (Mus musculus) PubMed

 3369.

IgaA is predicted to favor expression of the entire PhoP-PhoQ regulon based on its repression of the RcsC-YojN-RcsB phosphorelay[IgaA] (Mus musculus) PubMed

 3370.

results indicate that both SopD and SopD2 contribute to virulence in mice and suggest a functional relationship between these two proteins during systemic infection of the host [SopD2] (Mus musculus) PubMed

 3371.

the promoter binding ability of the PhoP and PmrA proteins occurring in low Mg2+ is correlated with phosphorylation of these proteins in vivo [PmrA] (Mus musculus) PubMed

 3372.

involved in adherence of Salmonella enterica serovar Typhimurium to human cells [OmpD] (Mus musculus) PubMed

 3373.

identification of genes regulated by PmrA and the roles of the identified genes in contributing to phenotypes associated with the PmrA-PmrB regulon [PmrA] (Mus musculus) PubMed

 3374.

We investigated the role of the 5' untranslated region in the Salmonella pathogenicity island-1 type III secretion system-mediated secretion of SopE. [SopE] (Mus musculus) PubMed

 3375.

PagL enzymatic deacylation is posttranslationally inhibited by membrane environments. [PagL] (Mus musculus) PubMed

 3376.

findings show that cdgR[for c-diguanylate (c-diGMP) regulator] is required for the bacterium to resist host phagocyte oxidase in vivo [CdgR] (Mus musculus) PubMed

 3377.

Full virulence of Salmonella typhimurium requires SseJ deacylase.(SseJ) (Mus musculus) PubMed

 3378.

to understand how CobA and FldA interact, a computer model of a CobA.FldA complex was generated; results indicate that Arg-9 and Arg-165 are important for CobA.FldA docking but not to catalysis [CobA] (Mus musculus) PubMed

 3379.

analysis of the spatial-temporal patterns of in vivo expression of genes of the PhoP and PmrA regulons and identification of the in vivo signals modulating their transcription [pmrA] (Mus musculus) PubMed

 3380.

Salmonella enterica serovar Typhimurium with mutations in the ompS1 and ompS2 genes, which code for quiescent porins, were nevertheless highly attenuated for virulence in a mouse model, indicating a role in pathogenesis [OmpS1, OmpS2] (Mus musculus) PubMed

 3381.

Wzzst expression controlled by PmrA/B and RcsC/YojN/RcsB systems. This suggests that the Wzzst protein is required under different environmental conditions.[Wzzst] (Mus musculus) PubMed

 3382.

membranes of S.typhimurium contain a novel hydrolase that removes the 3'-acyloxyacyl residue of lipid A in the presence of 5 mM Ca2+. the gene is designated lpxR, by screening an ordered S. typhimurium genomic DNA library (LpxR) (Mus musculus) PubMed

 3383.

PmrA-regulated lipopolysaccharide modifications aid Salmonella's survival and spread in non-host environments. [PmrA] (Mus musculus) PubMed

 3384.

Changes in cell surface due to LPS alteration in ddhC and waaG mutants result in significant changes in the production of both curli and cellulose and biofilm formation[waaG, ddhC] (Mus musculus) PubMed

 3385.

S. typhimurium PepN contributes significantly to cytosolic aminopeptidase activity and its role is manifested under selected stress conditions.[peptidase N] (Mus musculus) PubMed

 3386.

These data suggest that protease resistance is a critical property that allows SodCI to function in the harsh environment of the phagosome to combat phagocytic superoxide.[SodCI protein] (Mus musculus) PubMed

 3387.

A comparison of conformational differences that affect the structure of the active site between O-acetylserine sulfhydrylase A and O-acetylserine sulfhydrylase B (OASS-A and OASS-B). (Mus musculus) PubMed

 3388.

Cooperation between the SipA domains F1, F2 and 'actin-binding' domain is required to promote Salmonella virulence.[SipA] (Mus musculus) PubMed

 3389.

The native function of wild-type YhiT remains undetermined, but the collective results are consistent with a role as a general transporter of C4-dicarboxylates and other compounds with a similar basic structure.[YhiT] (Mus musculus) PubMed

 3390.

Expression of CopA depends on CueR and this transporter and the multicopper oxidase, CuiD are essential for full copper tolerance under aerobic and anaerobic conditions. [CuiD] (Mus musculus) PubMed

 3391.

Study shows that the three hydrogenase operons hyb, hya and hyd are expressed under different environmental conditions and are subject to control by different regulatory proteins.[hyb, hya, hyd] (Mus musculus) PubMed

 3392.

Taken together, the results reveal a combined role for NorV and NrfA in NO detoxification under anaerobic conditions, and highlight the influence that growth conditions have on the sensitivity to NO of this pathogenic bacterium.[NorV] (Mus musculus) PubMed

 3393.

CyaR (formerly RyeE) sRNA as an ompX repressor was identified;cyaR expression is tightly controlled by the cyclic AMP receptor protein, CRP.(CyaR) (Mus musculus) PubMed

 3394.

The mechanism of pathogenesis involves the PmrA-PmrB two-component system, which is activated in vivo by direct or indirect means and regulates genes that modify lipopolysaccharide, aiding survival in host (and non-host) environments. [PmrA, PmrB] (Mus musculus) PubMed

 3395.

the authors found that S. enterica serovar Typhimurium and S. flexneri activate different subtypes of phospholipase A(2), a critical enzyme involved in the liberation of arachidonic acid from cellular membranes.[phospholipase A2] (Mus musculus) PubMed

 3396.

These results suggest that the hydrogenases hya, hyb and hyd are used to oxidize hydrogen in different stages of an infection.[hya, hyb, hyd in strain JSG210] (Mus musculus) PubMed

 3397.

Mutations in the promoter region of ramA appear to play a role in the up-regulation of RamA and AcrAB, and RamA is an activator of the MDR regulation cascade in Salmonella Typhimurium.[RamA] (Mus musculus) PubMed

 3398.

Hya alone oxidizes the bulk of H(2) produced during fermentation.[Hya in strain 14028s] (Mus musculus) PubMed

 3399.

crystal structure and catalytic mechanism [LpxR] (Mus musculus) PubMed

 3400.

The results indicate that MviA regulates igaA transcription in an RpoS-dependent manner, but the results also suggest that MviA may regulate RcsB activation in an RpoS- and IgaA-independent manner. (Mus musculus) PubMed

 3401.

The opgGH mutant strain poorly colonized mouse organs when introduced orally along with the wild-type strain.[OpgH] (Mus musculus) PubMed

 3402.

Salmonella typhimurium showed a severe defect in motility and an attenuated phenotype in a competitive mouse infection experiment, where the DeltawbaP strain (SKI12) was directly compared to wild-type Salmonella.[wbaP] (Mus musculus) PubMed

 3403.

SopB vaccination reduced the bacterial burden of organs by about 5-fold on day 4 and day 8 after challenge with virulent Salmonella and proved to be a more efficient vaccination strategy than live attenuated bacteria alone[SopB ] (Mus musculus) PubMed

 3404.

Production of ArtA is induced by mitomycin C or H2O2, and ArtA is able to modify pertussis toxin-sensitive G proteins. [ArtA] (Mus musculus) PubMed

 3405.

SpiC is involved in flagella assembly by affecting the post-transcription expression of flhDC. [SpiC] (Mus musculus) PubMed

 3406.

ArcZ targets the coding sequence of tpx mRNA. Hfq is required for ArcZ mediated target repression. Overexpression alters the repertoire of Hfq-bound sRNAs. [ArcZ] (Mus musculus) PubMed

 3407.

the intracellular survival of most S. Typhimurium bacteria is conferred by the PhoPQ two-component regulator (PhoPQ) (Mus musculus) PubMed

 3408.

Omb is a previously unrecognized ferrous iron-binding protein. Omb may be involved in the acquisition of ferrous iron during the initial stages of SC infection and appears to be an important virulence factor. [omb/outer membrane beta-barrel protein] (Mus musculus) PubMed

 3409.

results suggest that the left inverted terminal repeat contains the sole BAdV-3 E1A promoter [E1A] (Mus musculus) PubMed

 3410.

E1B-156R, an early region 1B gene product of Adenovirus type 5, is a novel transformation-promoting E1B protein that acts without repressing p53 transactivation (E1B-156R). (Mus musculus) PubMed

 3411.

Expression of PAdV-3 E1Blarge inhibited the NF-kappaB dependent transcription of luciferase from IL-8 promoter.[E1B large protein] (Mus musculus) PubMed

 3412.

CUN085 is an occlusion body (OB) protein from the nucleopolyhedrovirus of Culex nigripalpus (CuniNPV) (Mus musculus) PubMed

 3413.

first crystal of a coxsackievirus B3 RNA-dependent RNA polymerase is reported (Mus musculus) PubMed

 3414.

Hypoxia-induced functional switch of complex II from succinate dehydrogenase to fumarate reductase, which subsequently leads to activation of voltage-gated calcium channels resulting in increased NO production by eNOS. (Mitochondrial complex II) (Mus musculus) PubMed

 3415.

data provide the first evidence that (E)-4-Hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE) is a ferredoxin-dependent enzyme in Thermosynechococcus elongatus BP-1 (Mus musculus) PubMed

 3416.

The isolation and characterization of NADH-quinone oxidoreductase-1 (NADH-1) in T. elongatus is reported.[NDH-1] (Mus musculus) PubMed

 3417.

Neurofascin isoforms, Nfasc155 in glia and Nfasc186 in neurons, are required for assembly of nodal and paranodal domains of myelinated axons and are essential for transition to saltatory conduction in developing vertebrate nerves. (Nfasc155 and 186) (Mus musculus) PubMed

 3418.

calcium ion is bound to the PsbO protein of photosystem II isolated from Thermosynechococcus elongatus. The Ca2+-binding site is located close to the lumenal exit of a putative proton channel leading from the water splitting site [PsbO] (Mus musculus) PubMed

 3419.

These results suggest that the epsilon subunit of chloroplast-type ATP synthase plays an important regulator for the rotary motor enzyme, thus preventing wasteful ATP hydrolysis.[F1-ATPase epsilon] (Mus musculus) PubMed

 3420.

PsbY is located in the periphery of photosystem II close to the alpha- and beta-subunits of cytochrome b559 (PsbY). (Mus musculus) PubMed

 3421.

Structure of PBP-A from Thermosynechococcus elongatus, a penicillin-binding protein closely related to class A beta-lactamases (Mus musculus) PubMed

 3422.

3C protease can localize in the nucleus and alter nucleocytoplasmic transport. [3C protease] (Mus musculus) PubMed

 3423.

Open reading frame 29 (ha29) is a gene specific for Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus (Ha29 gene) (Mus musculus) PubMed

 3424.

Increase of budded virus yield, decrease of virion production, and a smaller number of nucleocapsids produced in infected cells were result of fp25k deletion. No obvious changes of expression level of Ha133 and ODV-E66 were observed [FP25K] (Mus musculus) PubMed

 3425.

deletion of the C terminus of the ha2 product, a phosphatidylinositol 4-kinase homolog, dramatically decreased the viral titer, while deletion of 128 aa from the N terminus did not affect HA2 function.[HA2] (Mus musculus) PubMed

 3426.

espJ and tccP constitute an operon, whose expression in vitro is affected by the composition of the medium and environmental signals such as temperature, pH, osmolarity and O(2) pressure [espJ, tccP] (Mus musculus) PubMed

 3427.

We found that secretion of OtpA into the extracellular environment in E. coli O157:H7 requires OtpB and that when OtpA was produced in an E. coli K-12 strain, its secretion was strictly dependent on the production of OtpB.[OtpA, OtpB] (Mus musculus) PubMed

 3428.

the roles of NrfG in the formation of heme lyase complex (NrfEFG) and in the interaction between heme lyase complex and formate-dependent nitrite reductase (NrfA), we determined the crystal structure of NrfG at 2.05 A (Mus musculus) PubMed

 3429.

study demonstrates that the phenotypic change occurring during mouse passage correlates with stress response of outer membrane protein W (OmpW); upon induction of oxidative stress, OmpW was highly expressed only in the stress-sensitive MP37 strain [OmpW] (Mus musculus) PubMed

 3430.

Unlike other group III periplasmic binding proteins (PBPs), FitE forms dimers both in solution and in the crystals: [FitE] (Mus musculus) PubMed

 3431.

These studies suggest that in strain 43895OR, the murein lipoprotein Lpp indirectly regulates CsgA expression through the CpxAR system by a posttranscriptional mechanism. [CsgA, Lpp] (Mus musculus) PubMed

 3432.

REVIEW: Together, these regulatory proteins create a genetic circuit in which the cellular concentrations of CtrA and GcrA oscillate spatially and temporally to control daughter cell differentiation and cell cycle progression [CtrA] (Mus musculus) PubMed

 3433.

The crystal structure of the unorthodox response regulator PleD from Caulobacter crescentus, which consists of two CheY-like receiver domains and a diguanylate cyclase domain, has been solved in complex with the product c-diGMP. (PleD) (Mus musculus) PubMed

 3434.

experiments demonstrate that gyrB transcription does not require any auxiliary factors, suggesting that temporal regulation is not dependent upon an activator protein (Mus musculus) PubMed

 3435.

The flaF gene is required for motility and flagellin protein synthesis. (Mus musculus) PubMed

 3436.

data consistent with proposal that MalA actively transports maltodextrins; first example of an outer membrane protein for which an ExbB/ExbD-dependent transport of a nutrient other than iron & vitamin B(12) has been shown [MalA] (Mus musculus) PubMed

 3437.

MreC may function in the spatial organization of penicillin-binding proteins as well as other proteins that lie outside the cytoplasmic membrane [MreC] (Mus musculus) PubMed

 3438.

results show that DivL controls two key cell cycle regulators, CtrA and DivK, and that phosphoryl transfer is not DivL's essential cellular activity [DivL] (Mus musculus) PubMed

 3439.

Study shows that MreC is required for the spatial organization of components of the peptidoglycan-synthesizing holoenzyme in the periplasm and MreB directs the localization of a peptidoglycan precursor synthesis protein in the cytosol. [MreB,MreC] (Mus musculus) PubMed

 3440.

The xylX and at least one other promoter in the xylose regulon (PxylE) are controlled by the CC3065 (xylR) gene product, a LacI-type repressor.[XylR] (Mus musculus) PubMed

 3441.

when deleted the tonB gene encoded by the cc2334a ORF abolished maltose transport [TonB] (Mus musculus) PubMed

 3442.

NagA forms a small pore through which GlcNAc specifically diffuses into the periplasm and functions as an energy-coupled transporter for the larger chitin oligosaccharides.[NagA in strain JS1003] (Mus musculus) PubMed

 3443.

Since SpoT controls (p)ppGpp abundance, the authors propose that this nucleotide relays carbon starvation signals to the cellular factors responsible for activating DnaA proteolysis, thereby inhibiting the initiation of DNA replication.[SpoT & DnaA] (Mus musculus) PubMed

 3444.

crescentin also shares in vivo properties of assembly and dynamics with IF proteins by forming stable filamentous structures that continuously incorporate subunits along their length and that grow in a nonpolar fashion [crescentin] (Mus musculus) PubMed

 3445.

ShpA is likely to share a common mechanism for molecular recognition and phosphotransfer with yeast phosphotransfer protein YPD1 despite their low overall sequence similarity. (Mus musculus) PubMed

 3446.

analysis of structure, function, and targets of the transcriptional regulator SvtR from the hyperthermophilic archaeal virus SIRV1 [SvtR] (Mus musculus) PubMed

 3447.

crystallization of the complement component-3-binding domain of Efb and presentation of the results of single and multiwavelength anomalous diffraction studies on these crystals [Efb] (Mus musculus) PubMed

 3448.

results provide the first insight into the solution structure of full-length Eap and an experimental basis for interpreting the EAP domain crystal structures within the context of the full-length molecule [Eap] (Mus musculus) PubMed

 3449.

Contribution of point mutations to vancomycin resistance [graR] (Mus musculus) PubMed

 3450.

The specific binding of Efb to the putative receptor on the platelet surface results in a stimulated, non-functional binding of fibrinogen, distinct from natural binding of fibrinogen to platelets.(Extracellular fibrinogen binding protein, Efb) (Mus musculus) PubMed

 3451.

a possible regulatory relationship between the MazEF(Sa) TA module and the pathogenicity in S. aureus[MazF] (Mus musculus) PubMed

 3452.

hypothesized that SpyA is produced by S. pyogenes to disrupt cytoskeletal structures and promote colonization of the host [SpyA] (Mus musculus) PubMed

 3453.

The proteolytic effect of SpeB on 5 S. pyogenes superantigens is reported; only SpeZ was completely degraded by the enzyme.[SpeZ] (Mus musculus) PubMed

 3454.

amino acid requirements for IgG glycan-hydrolyzing activity of EndoS; findings show cysteine proteinase SpeB processes/degrades EndoS & emphasizes importance of SpeB as a degrading/processing enzyme of proteins from the bacterium itself [EndoS] (Mus musculus) PubMed

 3455.

By degrading the host defense peptide IL-8, the SpyCEP protease impairs neutrophil clearance mechanisms. [SpyCEP] (Mus musculus) PubMed

 3456.

SilCR upregulates the in vitro expression of sagA, siaA, and scpC, genes associated with S. pyogenes pathogenesis. [scpC] (Mus musculus) PubMed

 3457.

Linkage of Cpa to T3 by the sortase family transpeptidase SrtC2 requires the VPPTG motif in the cell wall-sorting signal of Cpa. [Cpa; T3] (Mus musculus) PubMed

 3458.

Here we provide evidence that, like Slmo, both the Prel and Retm proteins are localised to the mitochondria, indicating that the function of the PRELI/MSF1p' domain is specific to this organelle.[retm] (Mus musculus) PubMed

 3459.

PsaR-mediated gene regulation in response to Mn2 is required for full virulence in the establishment of pneumonia. [PsaR] (Mus musculus) PubMed

 3460.

the contribution of the blp locus, encoding putative bacteriocins and cognate immunity peptides, to intraspecies competition. (Mus musculus) PubMed

 3461.

in vitro transcriptional changes in pneumococcal rr09 mutants of two strains, D39 and TIGR4, by microarray analysis [rr09] (Mus musculus) PubMed

 3462.

The authors describe that the high calcium concentrations in the normal human host were toxic to pneumococci and that bacterial survival in vivo depended on CaxP, the first Ca2+ exporter reported in bacteria.[CaxP] (Mus musculus) PubMed

 3463.

RitR functionally interacts with the S. pneumoniae Ser-Thr kinase-phosphatase pair StkP and PhpP. RitR is phosphorylated by StkP at the C-terminal DNA-binding domain. [RitR; StkP; PhpP] (Mus musculus) PubMed

 3464.

The contribution of PpmA to virulence can be explained by its strain-specific role in adherence to epithelial cells and contribution to the evasion of phagocytosis. [PpmA/proteinase maturation protein A] (Mus musculus) PubMed

 3465.

assembly of the trimeric complex DivIB/DivIC/FtsL and co-localiation at division site is regulated through controlled formation of the DivIC/FtsL heterodimer. [DivIC] (Mus musculus) PubMed

 3466.

A serotyping technique based on sequences of various capsular proteins (cpsA AND cpsB AND wzy AND wzx) (Mus musculus) PubMed

 3467.

The role of the Yycf regulator on fatty acid biosynthesis and plasma membrane composition in Streptococcus pneumoniae. (Mus musculus) PubMed

 3468.

The crystal structure of virulence factor choline-binding protein e.(virulence factor choline-binding protein e). (Mus musculus) PubMed

 3469.

findings support the conclusion that the VicR response regulator strongly and directly regulates the transcription of a set of genes encoding the important surface proteins PspA and PcsB [PcsB, VicR] (Mus musculus) PubMed

 3470.

In this study, it was found that PcsB localizes to the plasma membrane and is released into the growth environment, yet it is detectable on the pneumococcal surface by flow cytometry analysis.[PcsB protein] (Mus musculus) PubMed

 3471.

Deletion replacement mutation in stkP conferred hypersensitivity to penicillin G. [StkP] (Mus musculus) PubMed

 3472.

Study presents the crystal structure of ORF14 of SIFV (Lipothrixviridae), a protein of 112 residues which has homologues in other archaeal viruses; SIFV-14 has a domain swapped structure and forms fiber structures in the crystal.[SIFV-14] (Mus musculus) PubMed

 3473.

Sip2 and Sip3 proteins, putative type I signal peptidases, are inhibited by arylomycin A2. [Sip2; Sip3] (Mus musculus) PubMed

 3474.

Critical residues for GP folding and viral entry identified in Ebola virus GP1 are conserved in Marburg virus. (Mus musculus) PubMed

 3475.

experiments demonstrated that mannose-binding lectin (MBL) binds to envelope glycoprotein resulting in important biological effects and suggest that MBL can interact with filoviruses during infection in humans [Env protein] (Mus musculus) PubMed

 3476.

Mass spectroscopic analysis indicated that primed GP(1,2) contains residues 33 to 190 of GP(1) and all residues of GP(2).[GP1 & GP2] (Mus musculus) PubMed

 3477.

cloned & overexpressed ArgF'in E. coli and show that it catalyzes the formation of N-acetyl-L-citrulline from N-acetyl-L-ornithine and carbamyl phosphate; designate this enzyme as an acetylornithine transcarbamylase [acetylornithine transcarbamylase] (Mus musculus) PubMed

 3478.

Opioid-derived peptide beta-endorphin is present in the genital tract of stallion, but is not locally produced as in other mammalian and nonmammalian models. (Mus musculus) PubMed

 3479.

data show that CmeR governs the expression of multiple genes with diverse functions and is required for Campylobacter adaptation in the chicken host [CmeR] (Mus musculus) PubMed

 3480.

MsrA and MsrB make a significant contribution to the protection of C. jejuni against oxidative and nitrosative stress. [MsrA] (Mus musculus) PubMed

 3481.

inhibition of respiration by NO may increase availability of oxygen for Cgb (part of NssR regulon) synthesis and function [Cgb/NssR] (Mus musculus) PubMed

 3482.

TGBp1, TGBp2, and TGBp3 are differed in cellular localization. [TGBp1, TGBp2, TGBp3] (Mus musculus) PubMed

 3483.

Te crystal structures of the open form RpiA from Vibrio vulnificus YJ106 (VvRpiA) in complex with the R5P and the closed form with arabinose-5-phosphate (A5P) in parallel with the apo VvRpiA at 2.0 A resolution, were determined.[RpiA] (Mus musculus) PubMed

 3484.

Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), have key roles in mycolic acid biosynthesis in Corynebacterianeae [accD2, accD3] (Mus musculus) PubMed

 3485.

activity og GlnK is regulated by adenylylation, cell membrane localization and degradation by at least three different proteases, FtsH, the ClpCP and the ClpXP protease complex in response to cellular nitrogen supply.[GlnK] (Mus musculus) PubMed

 3486.

findings indicated that MtrAB is involved in cell wall metabolism and influences the expression of genes involved in osmoprotection [mtrA] [mtrB] (Mus musculus) PubMed

 3487.

a gene (acnR) encoding a TetR-type transcriptional regulator was found to be encoded immediately downstream of the aconitase gene (acn) in C. glutamicum (Mus musculus) PubMed

 3488.

Depletion of ClpP1 and ClpP2 resulted in the accumulation of ClgR, indicating that ClgR is in fact a substrate of the ClpCP1 and/or ClpCP2 protease in C. glutamicum.[ClgR] (Mus musculus) PubMed

 3489.

PorH (C.glut), a cation-selective channel-forming protein, is coded in the bacterial chromosome by a gene that is localized in the vicinity of porA(C.glut), within a putative operon of 13 genes.[PorH(C.glut)] (Mus musculus) PubMed

 3490.

findings show that an AraC-type regulator, termed RipA for "regulator of iron proteins A," is involved in regulation of the aconitase gene under iron limitation [RipA] (Mus musculus) PubMed

 3491.

The isolation and characterization of RamA, a transcriptional activator, in C. glutamicum, is reported.[RamA] (Mus musculus) PubMed

 3492.

results suggested that Cg2831 is a transcriptional activator of cspB gene expression in C. glutamicum (Mus musculus) PubMed

 3493.

An experimental analysis of the membrane topology of Emb arabinofuranosyltransferase was presented. (Mus musculus) PubMed

 3494.

ppk2B gene (NCgl2620) corresponds to putative class II polyphosphate kinase. [ppk2B] (Mus musculus) PubMed

 3495.

During growth on media lacking L-lactate, LldR represses expression of quinone depedent L-lactate dehydrogenase. {LldR] (Mus musculus) PubMed

 3496.

Data show AmtA has a high substrate affinity and mediates saturable, membrane potential-dependent transport, which resulting in a high steady-state accumulation of methylammonium, even in the absence of metabolic trapping [AmtA] (Mus musculus) PubMed

 3497.

MptB as a PPM-dependent alpha(1-->6) mannosyltransferase, involved in early stages of proximal alpha(1-->6) core Cg-LM-A and Cg-LM-B biosynthesis in C. glutamicum. (Mus musculus) PubMed

 3498.

Data revealed that DccT, which is a member of the divalent anion/Na(+) symporter family, catalyzes the effective uptake of dicarboxylates like succinate, fumarate, L-malate, and likely also oxaloacetate in a sodium-dependent manner [dccT] (Mus musculus) PubMed

 3499.

a double AlaT and AvtA mutant was auxotrophic for L-alanine, showing that both ATs can provide L-alanine and that they are the only ATs involved.[AvtA] (Mus musculus) PubMed

 3500.

DNA microarray and DNase I footprint analyses suggested that LldR acts as a repressor regulating cgl2917-lldD and cgl1934-fruK-ptsF operons, which are indispensable for l-lactate and fructose/sucrose utilization, respectively (LldR). (Mus musculus) PubMed

 3501.

RbsR and UriR demonstrate a transcriptional co-control of the rbs and uriR operons and the rbsK2 gene, and recognize the same cognate DNA sequences in the operators of their target genes. [RbsR, UriR] (Mus musculus) PubMed

 3502.

The authors provide experimental evidence that a potential potassium channel (CglK) acts as the major potassium uptake system in a bacterium and proved CglK's function directly in its natural membrane environment.[CglK] (Mus musculus) PubMed

 3503.

The l-lactate dehydrogenase (Ldh) gene was shown to be regulated at the transcriptional level by SugR, a pleiotropic transcriptional repressor. [Ldh, SugR] (Mus musculus) PubMed

 3504.

The study show that LldR is another protein that binds to the ldhA promoter region, thus regulating ldhA expression.LldR has hitherto been characterized as an L-lactate-responsive transcriptional repressor of L-lactate utilization genes. New Gene: LldR (Mus musculus) PubMed

 3505.

These results suggest that the PS II-H protein is essential for stable assembly of native dimeric PS II complex containing PS II-X.[psII-x] (Mus musculus) PubMed

 3506.

PixJ, like SyPixJ1, is a novel photoreceptor in cyanobacteria ('cyanobacteriochromes') that are similar, but distinct from the phytochromes and bacteriophytochromes [PixJ] (Mus musculus) PubMed

 3507.

results indicated that the chromophore of TePixJ is not phycocyanobilin but its isomer, phycoviolobilin (PVB); it is suggested that the GAF domain of TePixJ has auto-lyase and auto-isomerase activities [PixJ] (Mus musculus) PubMed

 3508.

The results indicate that Tyr8 is not indispensable for the accumulation of the red-shifted form of PixD at least at 80 K.[PixD] (Mus musculus) PubMed

 3509.

The F1FO-ATP synthase of the thermophilic cyanobacterium Thermosynechococcus elongatus, was isolated and characterized.[F1FO ATP synthase] (Mus musculus) PubMed

 3510.

CphA catalyzed in vitro cyanophycin synthesis in the absence of a primer. [CphA] (Mus musculus) PubMed

 3511.

CrtG is a 2,2'-beta-hydroxylase involved in the biosynthetic pathway of the carotenoids nostoxanthin and 2-hydroxymyxol 2'-fucoside. [CrtG] (Mus musculus) PubMed

 3512.

the interaction with the FADH(*)-Y8(*) state occurred after the second photoexcitation of the photoinduced red-shifted states in the photocycle of TePixD [PixD] (Mus musculus) PubMed

 3513.

DNA sequence of the cloned ipaB was the same as ipaB from other Shigella flexneri. [ipaB] (Mus musculus) PubMed

 3514.

OspB and OspF localize to nucleus of host cells, reduce the amount of IL-8 secretion, and associate with Rb. [OspB; OspF] (Mus musculus) PubMed

 3515.

L* protein is shown to play an important role in virus persistence, TMEV-induced demyelination, and virus growth in macrophages. [L*] (Mus musculus) PubMed

 3516.

IFP35 can interact with the bovine Tas (BTas) regulatory protein of bovine foamy virus; overexpression of IFP35 disturbs the ability of BTas to activate viral-gene transcription and inhibits viral replication. (Mus musculus) PubMed

 3517.

These data suggest the dimerization region is necessary for the transactivational function of BTas and is crucial to the replication of Bovine foamy virus.[BTas] (Mus musculus) PubMed

 3518.

BibA is a novel multifunctional protein involved in both resistance to phagocytic killing and adhesion to host cells [BibA protein] (Mus musculus) PubMed

 3519.

prpZ, prkY and prkX are virulence genes that may be part of a signaling pathway controlling long-term survival of S. Typhi in host cells. [prpZ, prkY and prkX] (Mus musculus) PubMed

 3520.

Smu0630 is critical for biofilm formation [Smu0630] (Mus musculus) PubMed

 3521.

This study reveals that AtlA is a surface-associated protein that plays a critical role in the network connecting cell surface biogenesis, biofilm formation, genetic competence, and autolysis (Mus musculus) PubMed

 3522.

This study illustrates the central role of AtlA and VicK in orchestrating growth on surfaces and envelope biogenesis in response to redox conditions.[AtlA] (Mus musculus) PubMed

 3523.

LiaS sensor kinase regulates the expression of several genes coding for virulence factors. [LiaS] (Mus musculus) PubMed

 3524.

CiaX is part of the cia operon, and is required for calcium-mediated autoregulation and calcium-mediated biofilm formation. [CiaX] (Mus musculus) PubMed

 3525.

Compared to the parental strain UA159, the histidine kinase (liaS) mutant strain (IBS148) was more tolerant to various inhibitors that target protein synthesis, DNA synthesis and cell-wall biosynthesis. [LiaS] (Mus musculus) PubMed

 3526.

ClpL, ClpX and ClpP plays roles in the expression of key virulence traits of S. mutans. [ClpL] (Mus musculus) PubMed

 3527.

Under bacitracin stress conditions, the LiaFSR signaling system was shown to induce transcription of several genes involved in membrane protein synthesis, peptidoglycan biosynthesis, envelope chaperone/proteases, and transcriptional regulators.[LiaFSR] (Mus musculus) PubMed

 3528.

This study reveals that the control of agmatine deiminase (AgDS) gene expression by both agmatine and low pH is coordinated through the AguR protein and begins to identify domains of the protein involved in sensing and signaling.[AguR] (Mus musculus) PubMed

 3529.

In the presence of high concentrations of CSP pheromone, the unprocessed form of mutacin V acted as an intracellular auto-active bacteriocin causing S. mutans autolysis. [mutacin V] (Mus musculus) PubMed

 3530.

vicR expression was not autoregulated and was downregulated by the CSP in a ComX-independent manner. Expression of vicRKX is influenced by culture pH, growth phase and antibiotic stress, and is regulated by LiaFRS. [VicR] (Mus musculus) PubMed

 3531.

showed that CovS/CovR plays a major role in positively controlling S. agalactiae virulence [CovS][CovR] (Mus musculus) PubMed

 3532.

Threonine phosphorylation of CovR reduces its activation at the conserved aspartate and diminishes its ability to bind DNA and control gene expression. [CovR] (Mus musculus) PubMed

 3533.

ArcA is partially activated by a HptA, a small protein homologous to the histidine phosphotransfer domain of ArcB from E. coli [HptA] (Mus musculus) PubMed

 3534.

expression of Msr fusion proteins in bacterial pathogens is consistent with important role for this enzyme in maintenance of protein function necessary for bacterial survival under highly oxidizing conditions [MsrBA] (Mus musculus) PubMed

 3535.

Cultures grown under aerobic conditions with 25 microM copper showed significantly increased expression of cusA, whereas copA ighly induced under anaerobic conditions with 100 microM copper. [copA, cusA] (Mus musculus) PubMed

 3536.

The results indicated that CyaC plays a major role in regulating anaerobic respiration and may contribute to additional signaling pathways independent of AMP receptor protein. New Gene: cyaC (Mus musculus) PubMed

 3537.

We postulate that PsrA functions as the main subunit of the S. oneidensis S2O3(2-) terminal reductase whose end products (sulfide [HS-] or SO3(2-)) participate in an intraspecies sulfur cycle that drives S(0) respiration. [PsrA] (Mus musculus) PubMed

 3538.

MtrC (reductase) is shown to be kinetically competent to catalyze soluble iron reduction in whole cells but is not responsible for electron transfer via direct contact alone with insoluble iron-containing minerals. [MtrC] (Mus musculus) PubMed

 3539.

HlyU protein, a virulence factor up-regulates the expression of RtxA1 (repeats in toxin gene), a gene, responsible for cytotoxicity and virulence. [HlyU, RtxA1] (Mus musculus) PubMed

 3540.

sigma28-dependent class 3 gene expression was unaffected by flagellar shearing but was affected by the growth phase of the cell. (sigma28) (Mus musculus) PubMed

 3541.

appears to be one of 3 TTSS effector proteins in V. parahaemolyticus. [VPA450] (Mus musculus) PubMed

 3542.

From these experiments, the authors concluded that there is a T3S-associated chaperone, VecA, for a cytotoxic T3SS1-dependent effector, VepA.[VecA & VepA] (Mus musculus) PubMed

 3543.

null mutants of rpoH1, rpoE1, and rpoE2 are defective for survival in mice at 4 weeks postinfection. rpoH2 deletion strongly reduces the expression of two major virulence factors, the type IV secretion system and the flagellum.[rpoH1, rpoH2, rpoE1, rpoE2] (Mus musculus) PubMed

 3544.

A second LuxR-type regulatory protein,BlxR, was identified in Brucella militensis.(BlxR) (Mus musculus) PubMed

 3545.

data indicate that N-acetylglucosaminidase (AtlA) is not produced as a proenzyme and that control of the AtlA glucosaminidase activity is likely to occur at the level of LysM-mediated binding to peptidoglycan [AtlA] (Mus musculus) PubMed

 3546.

The data suggest that two secreted and coregulated proteases-GelE and SprE-are responsible for regulating autolysis and the release of high-molecular-weight eDNA, a critical component for the development of E. faecalis biofilms.[GelE and SprE] (Mus musculus) PubMed

 3547.

BgsA is a glycosyltransferase synthetizing diglucosyl-diacylglycerol, and is involved in biofilm accumulation. [bgsA] (Mus musculus) PubMed

 3548.

Presence of esp gene in Enterococcus faecalis isolates resistant to ampicillin was statistically higher than in susceptible strains, (esp protein, Enterococcus faecalis) (Mus musculus) PubMed

 3549.

A unique lysin from the streptococcal bacteriophage C1, termed PlyC, is composed of two separate gene products PlyCA and PlyCB, and defines a previously uncharacterized structural family of cell-wall hydrolases. (PlyC; lysin) (Mus musculus) PubMed

 3550.

Results show that Deinococcus radiodurans expresses a DNA polymerase belonging to the X family, PolX, which appears to play an important role in double-stranded DNA break repair [PolX]. (Mus musculus) PubMed

 3551.

Crtl gene controls the biosynthesis of red carotenoid including lycopene. [crtl] (Mus musculus) PubMed

 3552.

The desaturase activity of DR0861 (crtI) was further confirmed by the assay of enzyme activity in vitro and heterologous expression in Escherichia coli.[crtI] (Mus musculus) PubMed

 3553.

Data support the hypothesis that DrRRA contributes to the extreme radioresistance of D. radiodurans through its regulatory role in multiple pathways such as antioxidation and DNA repair pathways: [DrRRA] (Mus musculus) PubMed

 3554.

Data show that a recO null mutant exhibited a growth defect and extreme sensitivity to irradiation with gamma rays and UV light, suggesting that DNA repair in this organism occurs mainly via the RecF pathway [RecO] (Mus musculus) PubMed

 3555.

Results suggest that while the stable protein core DdrA157 is functional for DNA binding and gamma radiation protection in vitro, the carboxyl terminus is required for important functions in vivo: [DdrA] (Mus musculus) PubMed

 3556.

These results suggest a role, either directly or indirectly, for PprI as a general switch to efficiently enhance the DNA repair capability and extreme radioresistance of D. radiodurans via regulation of a series of pathways. (Mus musculus) PubMed

 3557.

DR2250 encodes carotenoid 3',4'-desaturase (CrtD), which catalyses the C-3',4'-desaturation of the monocyclic precursor of deinoxanthin but not acyclic carotenoids. [CrtD] (Mus musculus) PubMed

 3558.

deinococcal polymerase X is involved in DNA-damage tolerance of D. radiodurans, possibly by contributing to DNA double-strand break repair and base excision repair. [DNA polymerase X/PolX] (Mus musculus) PubMed

 3559.

Cobalamin-independent methionine synthase binding sites permit direct interaction of the substrates in a ternary complex. (Cobalamin-independent methionine synthase) (Mus musculus) PubMed

 3560.

new intracellular alkaline alpha-amylase identified and characterized to have a remarkably high pH optimum of pH 8.5 and an unusual sensitivity towards both ATP and EDTA.[AmyC] (Mus musculus) PubMed

 3561.

Recombinant EstD was found to exhibit significant esterase activity with preference for short acyl chain esters (C4-C8). monomeric enzyme has a molecular mass of 44.5 kDa & optimal activity around 95 degrees C at pH 7.[EstD] (Mus musculus) PubMed

 3562.

analysis on the thermostable MutL protein found in Thermotoga maritima MSB8 (MutL) (Mus musculus) PubMed

 3563.

Report characterized the first beta-1,2-mannosyltransferase that uses di-myo-inositol phosphate as the mannosyl acceptor. [beta-1,2-mannosyltransferase] (Mus musculus) PubMed

 3564.

the replication initiator gene rctB for oriCIIVC is under multiple negative and positive controls; multiple modes of control are expected to reduce fluctuations in the initiator concentration & help maintain chromosome copy number homeostasis [rctB] (Mus musculus) PubMed

 3565.

5-Methyl cytosine (m5C) was detected in genomic DNA of the enteric pathogen Vibrio cholerae by HPLC analysis and immunoblotting with m5C-specific antibody. [vchM] (Mus musculus) PubMed

 3566.

Study reports that the alternative sigma factor sigma(E) plays a critical role in determining V. cholerae resistance to antimicrobial peptides (AP) and that OmpU is a key determinant of basal sigma(E) expression. [sigmaE or rpoE protein] (Mus musculus) PubMed

 3567.

These data suggest that processing of MicX enhances its effectiveness, and that sRNA cleavage is not simply a means to sRNA inactivation and clearance.(MicX) (Mus musculus) PubMed

 3568.

These two toxin genes belong to the RTX family and are thought to play a role in pathogenicity. They display hemolytic activity, are involved with biofilm formation and cell adhesion, and contain cadherin domains. [rtxL1, rtxL2] (Mus musculus) PubMed

 3569.

vrrA gene is a small non-coding RNA which represses ompA translation and release of outer membrane vesicles. [vrrA] (Mus musculus) PubMed

 3570.

TrxA of the host strain is involved in the propagation of the VP3 phage.[TrxA] (Mus musculus) PubMed

 3571.

Based on these results, I discuss the potential roles of STRIP in T5 and T6 transcription and in initiating SSV-1 DNA replication. [T5, T6] (Mus musculus) PubMed

 3572.

required for aerobic but not for anaerobic growth [Mn-catalase] (Mus musculus) PubMed

 3573.

PaaK activity was upregulated during growth on phenylacetate or phenylalanine. [paaK] (Mus musculus) PubMed

 3574.

Binding of RNA substrates is mediated by the Hera C-terminal domain, but does not require a previously proposed putative RNase P motif within this domain (Hera). (Mus musculus) PubMed

 3575.

The authors identified an ATPase (tRNA-two-thiouridine C, TtuC) required for the 2-thiolation of s(2)T in Thermus thermophilus.[TtuC] (Mus musculus) PubMed

 3576.

Heat-resistant RNA-dependent ATPase (Hera) from Thermus thermophilus was overproduced in Escherichia coli and purified to homogeneity for studying the crystal structure.[Hera] (Mus musculus) PubMed

 3577.

A novel electron transport system for thermostable CYP175A1 from Thermus thermophilus HB27 (Mus musculus) PubMed

 3578.

These results demonstrated that Tomato leaf curl Java virus capsid protein shuttles between the nucleus and cytoplasm, such an activity homolog to bipartite geminivirus BV1 ORF.[capsid protein] (Mus musculus) PubMed

 3579.

Results describe the olsB gene, which is required for ornithine lipid biosynthesis [olsB]. (Mus musculus) PubMed

 3580.

role in Lipid A biosynthesis related to stress resistance and in alfalfa symbiosis [lpxXL, acpXL] (Mus musculus) PubMed

 3581.

role or RirA in regulation of genes involved in global iron metabolism, including Fe-S cluster formation (Mus musculus) PubMed

 3582.

identification of the rctA gene present in symbiotic plasmids; rctA gene seems to represent novel but probably widespread regulatory systems controlling the transfer of conjugative elements within the order Rhizobiales [rctA] (Mus musculus) PubMed

 3583.

Beta-ketoadipate succinyl-coenzyme A (CoA) transferase activity involved in protocatechuate metabolism in S. meliloti was shown to be encoded by SMb20587 and SMb20588, and these genes have been renamed pcaI and pcaJ, respectively. [PcaI, PcaJ] (Mus musculus) PubMed

 3584.

The expression of Lipopolysaccharide sulfotransferase (lpsS) is upregulated in strains that constitutively express the symbiotic regulator SyrA. [LpsS] (Mus musculus) PubMed

 3585.

the divalent cation-dependent transcriptional downregulation of lpsS is dependent on the exoR gene, which encodes a global regulator of transcription. (Mus musculus) PubMed

 3586.

we propose a model in which the symbiosis regulator CbrA functions as a developmental switch during symbiosis [CbrA] (Mus musculus) PubMed

 3587.

Sinorhizobium meliloti hpdA, which encodes the herbicide target 4-hydroxyphenylpyruvate dioxygenase, is positively regulated by HpdR.[HpdR] (Mus musculus) PubMed

 3588.

findings show that there are two triose phosphate isomerase encoding genes with different functions; tpiA is hypothesized to be constitutively active in a gluconeogenic role; tpiB is required for erythritol catabolism by an unknown mechanism [TpiA, TpiB] (Mus musculus) PubMed

 3589.

We demonstrated that Mur(Fur-like protein) protein binds with high affinity to the promoter region of mntA gene in a manganese-responsive manner. [Mur][MntA] (Mus musculus) PubMed

 3590.

We demonstrate that the ExpR/Sin quorum-sensing system controls motility gene expression through the VisN/VisR/Rem relay. [ExpR, Sin] (Mus musculus) PubMed

 3591.

Loss of ManX decreased expression of melA-agp and lac, the operons needed for utilization of alpha- and beta-galactosides, slowed growth on diverse carbon sources, and enhanced accumulation of high-molecular-weight succinoglycan.[ManX] (Mus musculus) PubMed

 3592.

GtrA and GtrB affect cell growth and effective symbiosis of S. meliloti [GtrA and GtrB] (Mus musculus) PubMed

 3593.

The PS-accumulating psd mutant, MAV01, initiated nodule formation much later than the wild type and formed 90% fewer nodules than the wild type.[psd] (Mus musculus) PubMed

 3594.

The authors show that the iron-regulated shmR gene encodes an outer membrane protein required for growth on heme.[ShmR] (Mus musculus) PubMed

 3595.

The analyses revealed that ExpR is a highly versatile regulator with a unique ability to show different regulatory capabilities in the presence or absence of an autoinducer. New Gene: ExpR (Mus musculus) PubMed

 3596.

The authors demonstrate that LpxXL and AcpXL play important but distinct roles in bacteroid development and that LpxXL is essential for the modification of S. meliloti bacteroid lipid A with VLCFAs.[LpxXL & AcpXL] (Mus musculus) PubMed

 3597.

EmmA may play a greater role in the overall fitness of S. meliloti both during the free-living stage and in its association with its host. [EmmA] (Mus musculus) PubMed

 3598.

analysis of Bmdbt and BmCKIalpha splice variants in Bombyx mori [Bmdbt, also called casein kinase Iepsilon] (Mus musculus) PubMed

 3599.

These results suggest that Bm33 (SNF2 global transactivator homologue) is not essential for virus growth in vitro or in vivo, but that it accelerates the time of death of B. mori larvae. [Bm33] (Mus musculus) PubMed

 3600.

FP25K is essential for the proper transcriptional regulation and efficient secretion of V-CATH. [FP25K] (Mus musculus) PubMed

 3601.

BM61 was a late structure protein localized in nucleus. [BM61] (Mus musculus) PubMed

 3602.

Two identical tandem genes rbr3A and rbr3B, which encode the heat shock protein Hsp21, show the transcription pattern of general stress genes (rbr3A, rbr3B). (Mus musculus) PubMed

 3603.

Mass spectrometric analysis of purified MccA from Wolinella succinogenes suggests that two of the single cysteine residues are actually part of an unprecedented CX15CH sequence involved in haem c binding.[MccA] (Mus musculus) PubMed

 3604.

Ldt(fm) is a novel peptidoglycan cross-linking enzyme for a beta-lactam-resistant transpeptidation pathway [Ldt(fm)] (Mus musculus) PubMed

 3605.

E. faecium blood culture-derived isolates harbouring esp had a significantly higher ability to acquire the vanA gene cluster in vitro when compared with esp- isolates [esp] (Mus musculus) PubMed

 3606.

Point mutations in penicillin-binding protein 5 (PBP5) and the levels of PBP5 expression were found to be significantly associated with ampicillin resistance. [PBP5] (Mus musculus) PubMed

 3607.

study demonstrates that Esp expression on the surface of E. faecium (i) varies consistently between strains, (ii) is growth condition dependent, and (iii) is quantitatively correlated with initial adherence and biofilm formation [esp] (Mus musculus) PubMed

 3608.

the C-terminal region of the pbp5 gene was highly polymorphic among the AmpR and AmpS isolates of animal origin; there seemed to be a correlation between specific changes located at positions close to the active site of PBP5 and the ampicillin MIC [pbp5] (Mus musculus) PubMed

 3609.

Results showed distinct characteristics in mutation patterns of ermB and ermA. (Mus musculus) PubMed

 3610.

The authors show with a rat endocarditis model that TX0082 Deltaacm::cat is highly attenuated versus wild-type TX0082.[Acm in strain TX0082] (Mus musculus) PubMed

 3611.

PilA and PilB are two fimbriae proteins. Expression is growth condition- and temperature-dependent. [PilA, PilB] (Mus musculus) PubMed

 3612.

E. faecium enterococcal surface protein Esp is not essential for high density colonization of the GI tract by nosocomial strains. [Esp] (Mus musculus) PubMed

 3613.

efmA is constitutively expressed under laboratory growth conditions and would contribute to intrinsic resistance against multiple antimicrobial agents in E. faecium FN-1. (Mus musculus) PubMed

 3614.

the first crystal structure of a member of the APH(2'') family of aminoglycoside phosphotransferases [Aminoglycoside-2''-phosphotransferase-IIa [APH(2'')-IIa]] (Mus musculus) PubMed

 3615.

Our findings suggest that Enterococcal surface protein, Esp also has a role in ampicillin sensitivity. [Esp] (Mus musculus) PubMed

 3616.

Esp expression enhanced in vitro binding to bladder and kidney epithelial cells [esp] (Mus musculus) PubMed

 3617.

the SgrA and EcbA surface proteins were characterized to gain insight into their function in hospital-acquired E. faecium infections (Mus musculus) PubMed

 3618.

RKA1 was upregulated in mycelial cells, indicate that an active PKA pathway promotes yeast-like growth and opposes mycelial development [protein kinase A] (Mus musculus) PubMed

 3619.

YlInp1p is a peripheral peroxisomal membrane protein that affects the partitioning of peroxisomes between mother cell and bud in Y. lipolytica. (Mus musculus) PubMed

 3620.

we report on the characterization of the Yarrowia lipolytica Ire1 ortholog. Our results show that Sls1, a nucleotide exchange factor for BiP, has important functions in regulating ER stress and the interaction of BiP and Ire1 (Sls1). (Mus musculus) PubMed

 3621.

Ind1 facilitates the assembly of Fe-S cofactors and subunits of complex I.[Ind1] (Mus musculus) PubMed

 3622.

{Snf7; Rim9; Rim23] YlRim23p is required for the alkaline pH response and interacts with YlSnf7 confirming the link between the Rim and Vps pathways, and deletion of the C-terminal tail of YlRim9p/PalI had no phenotypic effect on ambient pH signalling (Mus musculus) PubMed

 3623.

Our data suggest that ornithine decarboxylase (ODC) gene transcription is down-regulated by putrescine, and stimulated by spermidine. [ODC] (Mus musculus) PubMed

 3624.

The expression of FBP1 was not repressed by glucose. [FBP1] (Mus musculus) PubMed

 3625.

New components of Yarrowia lipolytica Golgi multi-protein complexes containing the alpha-1,6-mannosyltransferases YlMnn9p and YlAnl1p (Mus musculus) PubMed

 3626.

reveal an unprecedented role for members of the Pex3 protein family in peroxisome motility and inheritance in addition to their well-established role in peroxisome biogenesis at the endoplasmic reticulum.[Pex3] (Mus musculus) PubMed

 3627.

Data show that show that SC3 hydrophobin adopts the amyloid state at the water-PTFE interface:[SC3 hydrophobin] (Mus musculus) PubMed

 3628.

CgAUS1 appears to function as a sterol transporter that may contribute to lower azole susceptibility in the presence of serum and to protect C. glabrata against azole toxicity in vivo. [AUS1] (Mus musculus) PubMed

 3629.

role for SLT2 and chitin production in the response of C. glabrata to caspofungin. [SLT2] (Mus musculus) PubMed

 3630.

Data first demonstrate that CgSNQ2 contributes to the development of CgPDR1-dependent azole resistance in C. glabrata: CgPDR1 and CgSNQ2 (Mus musculus) PubMed

 3631.

Cta1 was required for resistance to oxidative stressi and this resistance was dependent on the stress-related transcription factors Yap1p, Skn7p, and Msn4p.[Cta1,Yap1p, Skn7p, Msn2p, and Msn4p] (Mus musculus) PubMed

 3632.

Three Epa family members functionally identified as adhesins in Candida glabrata (Epa1, Epa6 and Epa7) bind to ligands containing a terminal galactose residue.[Epa1, Epa6 and Epa7] (Mus musculus) PubMed

 3633.

Msn2 regulated general stress response in C. glabrata. [Msn2, Msn4] (Mus musculus) PubMed

 3634.

Rif1, Ku70 and Ku80 regulate silencing only a subset of genes at telomeres. [Rif1, Ku70 and Ku80 ] (Mus musculus) PubMed

 3635.

decreased susceptibilities of C. glabrata clinical isolates to azole antifungals mainly results from gain-of-function mutations in the gene encoding the CgPdr1p transcription factor [CgPdr1p] (Mus musculus) PubMed

 3636.

CgPho4 protein is necessary and sufficient for Pho2-independent gene expression. [PHO4, PHO2] (Mus musculus) PubMed

 3637.

Four crystal structures of C. glabrata FMNAT in different complexed forms were determined at 1.20-1.95 A resolutions[FMN adenylyltransferase] (Mus musculus) PubMed

 3638.

Data suggest that ascidian cellulose synthase is required for the coordination of the metamorphic events in the trunk and tail in addition to cellulose biosynthesis [cellulose synthase]. (Mus musculus) PubMed

 3639.

These findings suggest that functional homologues of both the BH1-3 death effector Bax and the pro-survival Bcl-XL exist in sea squirt Ciona intestinalis, and they control the cell death machinery independent of their heterodimerization.[Bax, Bcl-XL] (Mus musculus) PubMed

 3640.

Ci-p65, was transiently induced upon fertilization via T4 and found to exert its anti-apoptotic role in test cells nuclei as well as in a reconstituted cell system. (Ci-65) (Mus musculus) PubMed

 3641.

The C3a receptor molecule involved in C. intestinalis C3a-mediated chemotaxis has been cloned and characterized and its expression profile analyzed. [C3aR, complement 3a receptor] (Mus musculus) PubMed

 3642.

role in embryonic myogenesis of the MRF gene; we conclude MRF is required for larval tail muscle development and that an MRF-dependent myogenic regulatory network probably existed in the ancestor of tunicates and vertebrates [myogenic regulatory factor] (Mus musculus) PubMed

 3643.

The full-length htt mRNA of Ciona intestinalis was sequenced, characterized and compared with other chordate species. HTT. (Mus musculus) PubMed

 3644.

Ciona intestinalis APEX transcripts are clearly detectable in oocytes and embryos until the larva stage, but not in spermatozoa.(APEX) (Mus musculus) PubMed

 3645.

the ascidian genome contains a single ASIC gene that gives rise to two splice forms; proton-independent mechanisms mediate the effects of ASIC in vivo. [ASIC] (Mus musculus) PubMed

 3646.

Potential modulator of sperm-activating and sperm-attracting factor (SAAF) release from the egg. (Valosin-containing protein/p97) (Mus musculus) PubMed

 3647.

C. intestinalis Mras orthologue (Ci-Mras) was expressed in the neural complex of the ascidian juveniles after metamorphosis.[Mras] (Mus musculus) PubMed

 3648.

Misexpression of Lhx3b is sufficient to induce ectopic Mesp activation in cells expressing Tbx6b. Injection of antisense morpholino oligonucleotides showed that the Lhx3b isoform is required for endogenous Mesp expression.(Tbx6) (Mus musculus) PubMed

 3649.

Ciona intestinalis alternative oxidase expression appears to offer promise as a wide-spectrum therapeutic tool in oxidative phosphorylation disorders. (Mus musculus) PubMed

 3650.

Suggest that NO, specifically generated by nNOS, mediates sympathetic cardiac-cardiovascular responses through its action in the rostral ventrolateral medulla. (Mus musculus) PubMed

 3651.

Neither the hyperpermeability in response to simultaneous stimulation of VEGFR-1 and VEGFR-2 nor VEGFR-1-mediated severe inflammation was associated with VEGF-E(NZ7)/PlGF-induced angiogenesis. (VEGF-E(NZ7)) (Mus musculus) PubMed

 3652.

In this study, we show that both orf virus strains (NZ2 and NZ7)express equivalent levels of the viral VEGF variants and during infection of sheep skin induce comparable levels of vascularization, edema, epidermal rete ridge and scab formation. [VEGF] (Mus musculus) PubMed

 3653.

ORFV structural proteins 10 kDa and F1L fused to FlAG peptide were displayed on surface of infectious particles, whereas ORF110-FLAG localized to the Golgi of infected cells and egress from the cells. [10kda, F1L, ORF-110] (Mus musculus) PubMed

 3654.

Pseudorabies Viral envelope glycoprotein D (gD) was found to be necessary and sufficient for the induction of varicosities. (Mus musculus) PubMed

 3655.

extreme C terminus of (p)UL36 fulfills an essential role in pseudorabies virus replication, while a large internal portion of the C-terminal half of the protein is dispensable for replication in cell culture[(p)UL36] (Mus musculus) PubMed

 3656.

role of the 28-kDa amino-terminal product (nsp1) of the gene 1 polyprotein during replication of the coronavirus murine hepatitis virus (MHV) in cell culture. (nsp1 protein) (Mus musculus) PubMed

 3657.

the replicase gene of murine coronavirus JHM strain plays a role in hepatitis [replicase] (Mus musculus) PubMed

 3658.

Low doses of nsp1 mutant MHV elicited potent cytotoxic T cell responses and protected mice against virus challenge. (Mus musculus) PubMed

 3659.

matrix protein behaves like an integral membrane protein although its primary structure suggests it to be a peripheral membrane protein[matrix protein] (Mus musculus) PubMed

 3660.

The beta-ribbon structure folds over the peptide binding cleft and clearly contributes to substrate recognition by 3C protease (3C protease). (Mus musculus) PubMed

 3661.

results demonstrate that, in contrast to the betaG-betaH loop RGD motif, the second RGD sequence in the capsid protein 1D of NAM/307/98 does not function as a ligand for receptor binding in BHK-21 cells [capsid 1D] (Mus musculus) PubMed

 3662.

Molecular cloning and expression of two outer membrane proteins, BpsOmp38 (from Burkholderia pseudomallei) and BthOmp38 (from Burkholderia thailandensis)[omp38] (Mus musculus) PubMed

 3663.

The type IVA pilin-encoding gene, pilA, is essential for microcolony development by B. pseudomallei and thus optimum association with eukaryotic cells. (Mus musculus) PubMed

 3664.

A comprehensive biophysical analysis of the dynamic conformational behavior of the truncated monomeric needle subunit proteins MxiH(Delta5), BsaL(Delta5), and PrgI(Delta5), is presented.[BsaL] (Mus musculus) PubMed

 3665.

The full length (933 bp) gene of bipD, a member of TTSS cluster of Burkholderia pseudomallei, was isolated by PCR amplification from B. pseudomallei DNA and cloned into pGEX 4T-1 [BipD] (Mus musculus) PubMed

 3666.

a B. pseudomallei strain with mutation in the bsaQ gene, encoding a structural component of the type III secretion system (T3SS), was constructed. (Mus musculus) PubMed

 3667.

study identified the RpoS regulon; used Hidden Markov Model for prediction of RpoS-dependent promoters in 51 genes encoding 63 down-regulated proteins in rpoS(-) strain & defined the promoters, which were classified into 3 main groups [RpoS] (Mus musculus) PubMed

 3668.

the crystal structure of Cif [Cif] (Mus musculus) PubMed

 3669.

Here the authors show that isocitrate lyase is a persistence factor for B. pseudomallei, and inhibiting the activity of this enzyme during experimental chronic B. pseudomallei lung infection forces the infection into an acute state.[isocitrate lyase] (Mus musculus) PubMed

 3670.

Rgt1 binds to the RAG1 promoter in a glucose-dependent manner and represses RAG1 expression. (Rgt1) (Mus musculus) PubMed

 3671.

biochemical analysis and comparison of KlNde1p and KlNde2p [external alternative dehydrogenases KlNde1p and KlNde2p] (Mus musculus) PubMed

 3672.

unusual structure, so far found only in telomerase RNA, provides an essential and conserved telomerase-specific function[telomerase RNA] (Mus musculus) PubMed

 3673.

F1-ATPase inhibitor Inh1 (IF1) affects suppression of mtDNA loss-lethality. [IF1] (Mus musculus) PubMed

 3674.

study shows that Sck1 coordinates glucose import and glycolysis in K. lactis and that Rag8 controls this transcription factor by transcriptional and post-translational regulations [Sck1, Rag8] (Mus musculus) PubMed

 3675.

YND1 is isolated and characterized as an endopyrase that enhances the secretion of the recombinant human serum albumin and glucoamylase employed as reporters, and suppresses cell wall phenotypes and glycosylation defects. [YND1] (Mus musculus) PubMed

 3676.

The membrane-associated protein KNQ1, has a new unexpected role in iron homeostasis on which dithiothreitol tolerance may depend. [KNQ1] (Mus musculus) PubMed

 3677.

We identified a 15-bp element responsible for the transcriptional repression of mitochodnrial alcohol dehydrogenase (ADH3) by ethanol. [ADH3] (Mus musculus) PubMed

 3678.

From these results, it can be deduced that the K. lactis MATa cell produces the homolog of the S. cerevisiaealpha-pheromone, whereas the MATalpha cell produces the a-pheromone. [MATa, MATalpha] (Mus musculus) PubMed

 3679.

Transcription factor gene GCR1 is a suppressor of the fermentation regulator Rag3. [GCR1,Rag3] (Mus musculus) PubMed

 3680.

A novel glucokinase, Glk1, phosphorylates glucose, but fails to act on fructose as a sugar substrate.[Glk1] (Mus musculus) PubMed

 3681.

Double and triple deletion mutants of KlWSC1, KlWSC2/3 and KlMID2 genes show severe cell wall integrity defects. indicating overlapping functions.[KlWSC1, KlWSC2/3 and KlMID2 in strain KB6-2C] (Mus musculus) PubMed

 3682.

Two regulatory regions which contain the consensuses for KlGcr1p and KlMig1p binding are functional in the KlHEM1 promoter. (KlHEM1) (Mus musculus) PubMed

 3683.

A stable anticodon stem and the anticodon loop are the minimal requirements for cleavage by gamma-toxin (gamma toxin). (Mus musculus) PubMed

 3684.

The 5' arm of K. lactis telomerase RNA (TER) has critical roles in telomerase function, which may be linked to the function of Est3 [TER, Est3] (Mus musculus) PubMed

 3685.

Glycerol diminishes KlICL1 expression and a single carbon source responsive element (CSRE) sequence is both necessary and sufficient to mediate this regulation.[ICL1] (Mus musculus) PubMed

 3686.

The LAC1 protein of K. lactis is the enzyme that plays a crucial role in the synthesis of glucosylceramide. [LAC1] (Mus musculus) PubMed

 3687.

analysis of the molecular basis of Gal4p recognition by Gal80p [Gal4, Gal80] (Mus musculus) PubMed

 3688.

Regulation of PGS1 expression by myo-inositol and choline was not mediated at the transcriptional level. [PGS1] (Mus musculus) PubMed

 3689.

Disruption of the KlPCL1 gene neither impaired sporulation nor affected growth. [PCL1] (Mus musculus) PubMed

 3690.

Hap1 limits glucose uptake by repressing the expression of the glucose transporter gene RAG1. [Hap1, Rag1] (Mus musculus) PubMed

 3691.

These results demonstrate that Pdr1p is involved in Kluyveromyces lactis multidrug resistance and is required for cell's tolerance to various cytotoxic compounds.[Pdr1p in strain PM6-7A] (Mus musculus) PubMed

 3692.

Structure-activity relationships in Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease (Mus musculus) PubMed

 3693.

a protein homologous to transposases, called alpha3, was essential for mating type switch in Kluyveromyces lactis [alpha3] (Mus musculus) PubMed

 3694.

three different peptides belonging to the tandem repeat region of StPrP-2 from Takifugu rubripes have been considered; the coordination modes and conformations of their complexes with Cu(II) have been investigated [StPrP] (Mus musculus) PubMed

 3695.

The primary structures of a CXC chemokine (CXCL8) and two CXC receptors (CXCR) have been characterized in fugu, Takifugu rubripes [cxcL8, CXCR!, CXCR2] (Mus musculus) PubMed

 3696.

TLR3 and TLR22 link the IFN-inducing pathway via TICAM-1 [TICAM1][TLR3] (Mus musculus) PubMed

 3697.

Reduction of PmHHK1 expression produces significant changes in morphogenesis (including polarized growth), sporulation and cell wall composition. [histidine kinase/PmHHK1/Penicillium marneffei GX1005] (Mus musculus) PubMed

 3698.

full-length VP7 gene of Indian bluetongue virus (BTV) serotype 23 was sequenced and compared with prototype strains of BTV reported from different countries. (Mus musculus) PubMed

 3699.

gL from rhesus lymphocryptovirus plays role in the recruitment of gB in Epstein-Barr virus infected B-cell membrane fusion. [gL] (Mus musculus) PubMed

 3700.

The catalytic domain of glucuronoyl esterase from Hypocrea jecorina has been characterized; this is the first enzyme with glucoronoyl esterase activity to be crystallized. (glucuronoyl esterase) (Mus musculus) PubMed

 3701.

Lim1, despite its function in sulphur metabolite repression, responds both to light as well as sulphur- and carbon source[LIM1, E3 ubiquitin ligase protein] (Mus musculus) PubMed

 3702.

The data presented demonstrate that Aes1 and other homologous microbial proteins may represent a new family of esterases for lignocellulose biodegradation.[Aes1] (Mus musculus) PubMed

 3703.

GNA3 regulated cellulase gene expression by positively modulating its stimulation by light. [GNA3, cellulase] (Mus musculus) PubMed

 3704.

For Hypocrea jecorina grown on cellulose, the G-protein alpha subunit (GNA1) has a light-dependent role in regulation of cellulase and hydrophobin gene transcription. GNA1 also has a role in regulation of growth and stress tolerance [GNA1] (Mus musculus) PubMed

 3705.

findings strongly suggest the involvement of a protease recognition pattern at the cleavage site of the fusion protein as a determinant of virulence [F protein] (Mus musculus) PubMed

 3706.

findings show that two proteins, encoded by the un-spliced ORF from genomic segment 7 (s7ORF1) and the larger ORF from segment 8 (s8ORF2), are involved in modulation of the type I interferon (IFN) response. [s7ORF1, s8ORF2] (Mus musculus) PubMed

 3707.

EspG modulates enteropathogen's host cytoskeleton function involving transient microtubule destruction and actin polymerization [EspG] (Mus musculus) PubMed

 3708.

NleB is an essential virulence determinant of attaching and effacing pathogen Citrobacter rodentium (Mus musculus) PubMed

 3709.

significant loss of mitochondrial respiratory function in the infected intestinal epithelium; Map was implicated in the disruption of epithelial barrier function [Map protein] (Mus musculus) PubMed

 3710.

EspI modulates the virulence of attaching and effacing pathogens by binding host PDZ-domain proteins. (Mus musculus) PubMed

 3711.

This is the first report to describe the molecular mechanism by which an environmental chemical stimulates transcription of virulence-associated genes of an enteric pathogen through an AraC/XlyS-like activator,RegA.[RegA] (Mus musculus) PubMed

 3712.

RegA is a global regulator of virulence in C. rodentium which activates factors that are required for intestinal colonization. (Mus musculus) PubMed

 3713.

In conclusion, RpoS is important for the stress response and is required for full virulence in C. rodentium. (Mus musculus) PubMed

 3714.

These results suggest that EspT modulates the host cell cytoskeleton through coactivation of Rac-1 and Cdc42 by a distinct mechanism.[EspT] (Mus musculus) PubMed

 3715.

PhoPQ regulates croP expression and the presence of CroP at the outer membrane. CroP contributes to the protection of the OM from antimicrobial peptide damage by actively degrading alpha-helical AMPs. [CroP] (Mus musculus) PubMed

 3716.

The presence of bicarbonate relieves the autoinhibition of RegA activity by its N-terminal arm.[RegA] (Mus musculus) PubMed

 3717.

Our data suggest that HCR2 is involved in HCS and identification of the gene may contribute to understanding the mechanisms for production of a hypercoagulable state of several critical clinical disorders. [hypercoagulability related gene-2 (HCR2)] (Mus musculus) PubMed

 3718.

assembly of early viral chromatin requires both the association of SET/TAF-1beta and the release of protein VII.[protein VII] (Mus musculus) PubMed

 3719.

We identified a novel interaction between E4 ORF3 and TIF1alpha [E4 ORF3] (Mus musculus) PubMed

 3720.

UXP is a previously unrecognized protein derived from a novel late l-strand transcription unit with suggested function of DNA replication or RNA transcription.[UXP] (Mus musculus) PubMed

 3721.

describes the mechanism of FX binding to Ad5 and demonstrates the critical role of hexon for virus infection of hepatocytes in vivo. [hexon capsid proteins] (Mus musculus) PubMed

 3722.

An NF-kappa B-independent pathway is defined through which the E1A oncogene of human adenovirus sensitizes mouse and human cells to apoptosis by enhancement of caspase-2-mediated mitochondrial injury. [early region 1A oncogene; E1A oncogene] (Mus musculus) PubMed

 3723.

PML was found to be important for E1A-induced suppression of EGFR and subsequent killing of head and neck squamous cell carcinoma cells suggesting a novel pathway involving PML and p73 in the regulation of EGFR expression.[E1A] (Mus musculus) PubMed

 3724.

ORF3 protein of porcine circovirus (PCV) type 2 plays an important role in PCV2 viral pathogenesis via its apoptotic activity.[ORF3] (Mus musculus) PubMed

 3725.

Results show that the PCV2 ORF3 protein specifically interacts with pPirh2 and inhibits its stabilization; this may lead to increasing p53 expression, resulting in apoptosis.[ORF3 protein] (Mus musculus) PubMed

 3726.

The ORF3 mutant virus did not cause any observable disease or perturbation of the lymphocyte count in the inoculated piglets and elicited an efficient immune response. (Mus musculus) PubMed

 3727.

The DNA binding potential and the significant region that confers the nuclear localization of the Rep protein were characterized. (Mus musculus) PubMed

 3728.

The class III chitin synthase gene contains 2,739 bp and encodes a protein with 913 aa. [chitin synthase ] (Mus musculus) PubMed

 3729.

Blotched snakehead virus (BSNV) is a member of the Birnaviridae family that requires a virally encoded protease known as VP4 in order to process its polyprotein into viral capsid protein precursors (protease VP4) (Mus musculus) PubMed

 3730.

Ssk2 is a critical interface connecting the two-component system and the Pbs2-Hog1 MAPK pathway in C. neoformans [Ssk2, Pbs2, Hog1] (Mus musculus) PubMed

 3731.

Sxi1alpha and Sxi2a control sexual development in a homeodomain-dependent fashion using DNA-binding sequences different from those defined previously for fungi. [Sxi1alpha;Sxi2a] (Mus musculus) PubMed

 3732.

An essential role for acetate permease A (AcpA)in mediated acetate transport (AcpA). (Mus musculus) PubMed

 3733.

Taken together, these results suggest that ArfA participates in hyphal growth through the secretory system.[ArfA] (Mus musculus) PubMed

 3734.

CrzA and SltA are both capable of binding DNA and SltA acts positively on transcription of the Ena1p-like Na+ pump gene enaA and negatively on transcription of the putative vacuolar Ca2+/H+ exchanger gene vcxA (CrzA and SltA). (Mus musculus) PubMed

 3735.

study identified the VelB/VeA/LaeA complex connecting light-responding developmental regulation & control of secondary metabolism; VeA interacts with VelB; VeA bridges VelB to the nuclear master regulator of secondary metabolism, LaeA [VelB, VeA, LaeA] (Mus musculus) PubMed

 3736.

The results strongly support the view that during growth, FadA/SfaD/GpgA G protein signaling inhibits proteinase production via both Galpha and Gbetagamma subunits.[FadA, SfaD, GpgA] (Mus musculus) PubMed

 3737.

Apoptosis-Inducing Factor-like mitochondrial oxidoreductase transcription is induced by farnesol and is improtant for decreasing the effects of farnesol and reactive oxygen species. [aifA] (Mus musculus) PubMed

 3738.

analysis of the fungal phytochrome FphA from Aspergillus nidulans [FphA] (Mus musculus) PubMed

 3739.

ugmADelta strains had compact colonial growth, which was associated with substantially delayed and abnormal conidiation.[ugmA in strain A1149] (Mus musculus) PubMed

 3740.

Disruption of aatB resulted in a reduced penicillin titre.[[AatB] (Mus musculus) PubMed

 3741.

FlbE is an upstream developmental activator which functions in close association with putative transcription factor FlbB. [FlbE] (Mus musculus) PubMed

 3742.

Overexpression of imeB results in efficient sexual differentiation independently of light and repression of asexual development. ImeB is also needed for expression of the sterigmatocystin gene cluster. [ImeB] (Mus musculus) PubMed

 3743.

ChiB is necessary for the DeltaflbA-induced autolysis. [ChiB] (Mus musculus) PubMed

 3744.

This is believed to be the first report demonstrating the presence of soluble alpha1,2-mannosidase from the glycosyl hydrolases family 47 in a cytosolic compartment of the cell. [alpha1,2-mannosidase] (Mus musculus) PubMed

 3745.

CaPTC8 plays a role in stress responses and is required for the yeast-hyphal transition, and the CaPTC8-related genes are evolutionarily conserved.[CaPTC8] (Mus musculus) PubMed

 3746.

RHB1 and TSC2 are involved in nitrogen starvation-induced filamentation. [Tsc2] (Mus musculus) PubMed

 3747.

Ena21 is a sodium ion transporter that increases salt tolerance. [Ena21] (Mus musculus) PubMed

 3748.

Rfx2p regulates DNA damage responses, morphogenesis, and virulence. [RFX2] (Mus musculus) PubMed

 3749.

Histological examination confirmed that the vps21Delta and ypt72Delta mutants are deficient in hyphal growth in vivo.[ypt72] (Mus musculus) PubMed

 3750.

Msb2 is involved in the transmission of the signal toward Cek1 mediated by the Cdc42 GTPase. [Msb2] (Mus musculus) PubMed

 3751.

an analysis of sequences of the large subunit which reliably finds specificity-enhancing mutations and ranks them according to the probability of success. (Mus musculus) PubMed

 3752.

The control mechanism of the unique light-responsive groE expression is highly diversified in cyanobacteria [groESL1] (Mus musculus) PubMed

 3753.

48 of the 108 copies of the 5S rRNA genes are located 3' of tRNA genes (5S rRNA). (Mus musculus) PubMed

 3754.

crystal structure of TT1751 at 2.0 angstrom resolution [TT1751] (Mus musculus) PubMed

 3755.

We report here the sat1 gene encoding L-serine O-acetyltransferase[SAT] of an extreme thermophile, Thermus thermophilus HB8.[sat1] = L-serine O-acetyltransferase, Thermus thermophilus HB8] (Mus musculus) PubMed

 3756.

TT1662 from Thermus thermophilus HB8 is a member of the alpha/beta hydrolase fold enzymes (Mus musculus) PubMed

 3757.

The crystal structure of a novel polyprenyl pyrophosphate binding protein, TT1927b, from Thermus thermophilus HB8, complexed with its ligand (TT1927b). (Mus musculus) PubMed

 3758.

X-ray crystallographic structure of a purine/pyrimidine phosphoribosyltransferase-related protein from the thermophilic bacterium, Thermus thermophilus HB8 [APRTase] (Mus musculus) PubMed

 3759.

The hydrophilic domain (peripheral arm) of the proton-translocating NADH:quinone oxidoreductase (complex I) from the thermophilic organism Thermus thermophilus HB8 has been purified and characterized[Nqo15] (Mus musculus) PubMed

 3760.

A structural insight into the DNA recognition by this protein. [AT-rich DNA-binding protein; p25] (Mus musculus) PubMed

 3761.

Hypothetical protein TTHA0281 is speculated to be involved in RNA metabolism, including RNA binding and cleavage. (Mus musculus) PubMed

 3762.

Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8 (Mus musculus) PubMed

 3763.

latter loop further changes its conformation upon binding of 4-hydroxyphenylacetate 3-monooxygenase and obstructs the active site from the bulk solvent[4-hydroxyphenylacetate 3-monooxygenase ] (Mus musculus) PubMed

 3764.

The crystal structure of PaaG from Thermus thermophilus HB8 was determined at a resolution of 1.85 A. PaaG consists of three identical subunits related by local three-fold symmetry.[PaaG] (Mus musculus) PubMed

 3765.

To further examine V. fischeri lipid A and its symbiotic function, we identified two paralogs of htrB (designated htrB1 and htrB2) and an msbB gene in strain ES114 and demonstrated that these genes encode lipid A secondary acyltransferases. [htrB, msbB] (Mus musculus) PubMed

 3766.

An antimicrobial agent hypersensitive strain of Escherichia coli harboring murA from V. fischeri exhibited a high fosfomycin resistance phenotype, with minimum inhibitory concentration of 3,000 microg/ml.[MurA in strain VF107] (Mus musculus) PubMed

 3767.

identification of a serine-aspartate repeat protein that binds collagen. [SrdI] (Mus musculus) PubMed

 3768.

Systems pivotal for the organism's defense against photooxidative stress are strongly dependent on glutathione and are recognized by RpoH(II) in R. sphaeroides[RpoH(II)] (Mus musculus) PubMed

 3769.

X-ray structure of the L protein (BchL) of the dark-operative protochlorophyllide reductase has been determined with bound MgADP to 1.6 A resolution [bchL] (Mus musculus) PubMed

 3770.

Results indicate that the lipid membrane acts to accelerate proton uptake by the membrane-bound proton transporter cytochrome c oxidase of Rhodobacter sphaeroides.(cytochrome c oxidase / cytochrome aa3) (Mus musculus) PubMed

 3771.

Results suggests the 17(3)-ester group of the bacteriochlorophyll P(A) to be involved in covalent interaction with the I(L177) photosynthetic reaction center subunit H (photosynthetic reaction center subunit H). (Mus musculus) PubMed

 3772.

Hetero-oligomeric FleQ/FleT activated flagellar promoters through a conserved binding site. [FleQ, FleT] (Mus musculus) PubMed

 3773.

The Raman results reported here demonstrate that R481 residue in cytochrome c oxidase plays a critical role in supporting efficient proton pumping, by holding the heme groups in a proper environment.[cytochrome c oxidase] (Mus musculus) PubMed

 3774.

results indicate that AppA17-133 and AppA1-126 contain Trp104 in distinct alternate conformations in solution and that light absorption by the flavin causes partial movement/uncovering of Trp104 (AppA). (Mus musculus) PubMed

 3775.

The 74-kDa MDH is involved in tricarboxylic acid cycle, while the 148-kDa MDH takes part in the citramalate pathway/ [MDH] (Mus musculus) PubMed

 3776.

effect of ionic strength on the second-order electron transfer rate constant, k(2), between cyt c(2) and native or mutant RCs[cytc2] (Mus musculus) PubMed

 3777.

T. fusca cutinases adopt an alpha/beta-hydrolase fold that exhibits both similarities and variations from the fungal cutinase structure (Mus musculus) PubMed

 3778.

Expression patterns of cel5A and cel5B, two endoglucanase encoding genes were compared; the relative expression levels of cel5A were always higher than those of cel5B.(cel5A)(cel5B) (Mus musculus) PubMed

 3779.

D274A Cel6B and its catalytic domain bound more tightly to both bacterial microcrystalline cellulose and swollen cellulose, respectively, than the wild-type Cel6B[exocellulase Cel6B] (Mus musculus) PubMed

 3780.

CYP709C1 is a sub-terminal hydroxylase of long chain fatty acid in plants (Mus musculus) PubMed

 3781.

DPE1-e exhibits disproportionating activity in vitro by cleaving maltotriose to produce glucose as well as being able to use maltoheptaose as the donor for the addition of glucans to the outer chains of glycogen and amylopectin. (Mus musculus) PubMed

 3782.

Transcripts were detectable in the developing palea, but not in other floral organs, suggesting that WFL may play a novel role in developing palea in the wheat floret. (WFL = wheat FLO/LFY) (Mus musculus) PubMed

 3783.

Wheat genome contains three similar genes of translation initiation factors 5A, eIF5a1 eIF5a2 and eIF5a3. [eIF5a1 eIF5a2 and eIF5a3] (Mus musculus) PubMed

 3784.

SUT1B/D functions to transport Sucrose into the scutellum from the endosperm early in germination and later transports maltose. [SUT1B] & [SUT1D] (Mus musculus) PubMed

 3785.

The roles of glutamine synthetase and NADH-dependent glutamate dehydrogenase in the accumulation of proline was determined in leaves of wheat seedlings exposed to salt stress. [GS & NADH-GDH] (Mus musculus) PubMed

 3786.

findings suggest reductions in populations of Diuraphis noxia fed Dnx plants are related to the expression of sequences involved in defensive chemical production, cellular transport, and exocytosis. [Dnx] (Mus musculus) PubMed

 3787.

The STS Xhor2kv and SSR Xgdm33 are two flanking markers that are tightly linked to H22 at genetic distances of 0.3 and 1.0 cM, respectively.(H22) (Mus musculus) PubMed

 3788.

isolation and characterization of a cDNA clone encoding RanBP from wheat; it is expressed ubiquitously in roots, leaves and stems, with a similar abundance in these tissue [RanBP1] (Mus musculus) PubMed

 3789.

Qualitative mapping of Fhb2 in wheat provides tightly linked markers that can reduce linkage drag associated with marker assisted selection of Fhb2 and aid the pyramiding of different resistance loci for wheat improvement. (Mus musculus) PubMed

 3790.

cloning of Gpc-B1, a QTL associated with increased grain protein, zinc & iron content; ancestral wild wheat allele encodes NAM-B1 that accelerates aging & increases nutrient mobilization to developing grain; modern wheat has nonfunctional allele [NAM-B1] (Mus musculus) PubMed

 3791.

This work is the first report of mapping Psy genes and supports the role of Psy1-1 in elevated levels of endosperm colour in durum wheat.[Phytoene synthase] (Mus musculus) PubMed

 3792.

high molecular weight glutenin subunit allele 1Bx23 in common wheat (Mus musculus) PubMed

 3793.

The LR1RGA1 encoding a CC-NBS-leucine-rich repeat type of protein, represents a very good candidate for the leaf rust resistance gene, Lr1 (LR1RGA1). (Mus musculus) PubMed

 3794.

There are conserved cis-acting elements and trans-acting factors that enable the TaPT2 promoter to be regulated in a tissue-specific and Pi-dependent fashion in both monocots and dicots. [PT2] (Mus musculus) PubMed

 3795.

Lr21-mediated signaling pathways require the wheat homologs of RAR1, SGT1, and HSP90[RAR1] (Mus musculus) PubMed

 3796.

data provide molecular evidence that TaVRN1 may have pleiotropic effects in various processes such as control of axillary bud growth, transition to flowering and development of floral organs [TaVRN1] (Mus musculus) PubMed

 3797.

Mutations within the Viviparous-1B gene are linked to abscisic acid sensitivity and resistance to pre-harvest sprouting. (Mus musculus) PubMed

 3798.

characterization of three new wheat receptor-like kinase (RLK) genes (TaRLK-R1, 2 and 3); transcript levels of TaRLK-R1, 2 and 3 increased during the hypersensitive reaction to stripe rust fungus [RLK-R1, RLK-R2, RLK-R3] (Mus musculus) PubMed

 3799.

The results are consistent with the hypothesis that chloroplast EF-Tu plays a functional role in heat tolerance by acting as a molecular chaperone.[EF-Tu] (Mus musculus) PubMed

 3800.

SR07 fragment may play an important role in the water regulation of the plant. [SR07] (Mus musculus) PubMed

 3801.

tin3 gene was mapped to a 324-kb region spanned by two overlapping bacterial artificial chromosomes (BACs) of rice chromosome arm 1L [tin3] (Mus musculus) PubMed

 3802.

A cDNA (TaCM, caffeic acid 3-O-methyltransferase was identified from wheat and it was found to be expressed constitutively in stem, leaf and root tissues. (Mus musculus) PubMed

 3803.

The first evidence of FNR (isolated from spinach and from wheat) interaction directly with a model membrane without the mediation of any additional protein, is presented.[FNR] (Mus musculus) PubMed

 3804.

results imply that stage-specific transcription of TaBx3 and TaBx4 is not controlled by global sequence similarity of their promoters but by some essential cis-elements [Bx3 & Bx4] (Mus musculus) PubMed

 3805.

These data demonstrate that eIFiso4F can kinetically compete with eIF4F for VPg binding.[eIF4F, eIFiso4F] (Mus musculus) PubMed

 3806.

These results support the hypothesis that allelic differences in PSY-1 and at least one additional gene in the distal region of the long arm of homoeologous group 7L are associated with differences in grain yellow pigment content.[PSY-1] (Mus musculus) PubMed

 3807.

SOS1 expressed in yeast cells lacking major endogenous sodium transporters restored salt tolerance and enhanced sodium/hydrogen exchange at the plasma membrane. (SOS1) (Mus musculus) PubMed

 3808.

a cDNA clone encoding wheat CRT was successfully isolated and the results suggest that TaCRT is involved in the plant response to drought stress, indicating a potential in the transgenic improvements of plant water-stress [CRT] (Mus musculus) PubMed

 3809.

The populations of wild emmer wheat showed a wide range of diversity in dimeric alpha-amylase inhibitors, both between and within populations (WDAI-3 (Mus musculus) PubMed

 3810.

These observations implied that TaF(A)d is under mitochondrial retrograde regulation in the anthers of cytoplasmic male sterility plants with timopheevii cytoplasm.[TaF(A)] (Mus musculus) PubMed

 3811.

Pm36, a gene conferring powdery mildew resistance, has been mapped to Triticum chromosome 5. [Pm36] (Mus musculus) PubMed

 3812.

The RIP (tritin) activity and RIP-RALyase-mediated cleavage of SRD in the cytoplasmic ribosome were induced at the late stage of senescence of wheat coleoptiles.(RALyase) (Mus musculus) PubMed

 3813.

results provide evidence that there have been only few evolutionary changes in Hv- and TaGAMYB; this confirms the close relationship between these species and also highlights the functional importance of this transcription factor [GAMYB] (Mus musculus) PubMed

 3814.

Expression of the cold-Regulated genes, Wcs120, Wcor410, and Wcor14 was differentially regulated in the leaf and crown tissues.[Wcor14] (Mus musculus) PubMed

 3815.

genomic locations of Lr48 and Lr49 genes [Lr48; Lr49] (Mus musculus) PubMed

 3816.

TaCHSL1 is an anther-specific chalcone synthase-like gene which is highly expressed in the tapetum. [TaCHSL1] (Mus musculus) PubMed

 3817.

LrZH84 is mapped as a new leaf rust resistance gene. (Mus musculus) PubMed

 3818.

Four loci responsible for the activity of disulfide reductase were identified on chromosomes 4A, 5D, 6A, and7D. [disulfide reductase] (Mus musculus) PubMed

 3819.

In order to reveal the mechanism by which 1By16 and 1Bx13 creates high quality, their open reading frames were amplified from common wheat Atlas66 and Jimai 20.[1Bx13, 1By16] (Mus musculus) PubMed

 3820.

The mitochondrial gene orf260cra causes pistillody in alloplasmic wheat. [orf260cra] (Mus musculus) PubMed

 3821.

These results suggested that TaAIDFa encodes a CRT/DRE element-binding factor that might be involved in multiple abiotic stress signal transduction pathways.[AIDFa] (Mus musculus) PubMed

 3822.

The powdery mildew resistance gene Pm23 is relocated on chromosome 2AL. [Pm23] (Mus musculus) PubMed

 3823.

Ph1 suppresses homoeologous chromosome interactions by regulating the level of TaASY1 expression during meiosis. [Ph1] (Mus musculus) PubMed

 3824.

Structural and expressional divergence of genes encoding O-methyltransferase in wheat.[TaOMT4, TaOMT5]. (Mus musculus) PubMed

 3825.

YrC591 is a novel stripe rust resistance gene in wheat. (Mus musculus) PubMed

 3826.

Lr34 is a leaf rust resistance gene that helps upregulate genes associated with defense and stress-related proteins, secondary metabolism enzymes, and transcriptional regulation and cellular-signaling proteins. [Lr34] (Mus musculus) PubMed

 3827.

MATE1 contributes to aluminum resistance via the citrate efflux pathway. [TaMATE1] (Mus musculus) PubMed

 3828.

sdi1 expression was specifically induced in leaf and root tissues in response to sulphate deficiency. [sdi1] (Mus musculus) PubMed

 3829.

Two unexpressed 1By genes from Triticum aesitvum L.ssp.yunnanese AS332 and T. aesitvum ssp.tibetanum AS908 were respectively cloned and characterized.[Glu-B1] (Mus musculus) PubMed

 3830.

Large differences exist in relative expression levels of alpha-gliadins from the homoeologous Gli-2 loci among wheat genotypes. [Gli-2] (Mus musculus) PubMed

 3831.

Upregulation of VRN1 during the light period was followed by the accumulation of FLOWERING LOCUS T. [VRN1] (Mus musculus) PubMed

 3832.

the gene Lr34 confers resistance to multiple fungal pathogens; findings show the LR34 protein resembles ABC transporters of the pleiotropic drug resistance subfamily; alleles of Lr34 conferring resistance or susceptibility differ by 3 polymorphisms [Lr34] (Mus musculus) PubMed

 3833.

After refolding and purification, TaGluD with 1 unit of beta-1,3-glucanase showed antifungal activity in vitro against Rhizoctonia solani, Rhizoctonia cerealis, Phytophthora capsici and Alternaria longipes.[GluD] (Mus musculus) PubMed

 3834.

TaCPS3 is responsible for gibberellin biosynthesis, while TaCPS1 and TaCPS2 are possible functional homologs of diterpene cyclase genes OsCPS2 and OsCPS4 involved in phytoalexin biosynthesis in rice [CPS1; CPS2; CPS3] (Mus musculus) PubMed

 3835.

Pea enation mosaic virus RNA 2 cap-independent translation elements binds eIF4F and its eIF4E subunit with high affinity.[eIF4F] (Mus musculus) PubMed

 3836.

Comparative mapping of the soft glume (sog) gene of diploid Triticum monococcum L. and tenacious glume (Tg) gene of hexaploid T. aestivum L, is reported.[sog, Tg] (Mus musculus) PubMed

 3837.

CM gene expression, enzyme activity, and protein content were associated with the lodging-resistant phenotype in wheat. [CM] (Mus musculus) PubMed

 3838.

Pho1 enzyme activity levels were shown to increase throughout the period of starch synthesis [Pho1, starch phosphorylase] (Mus musculus) PubMed

 3839.

Glo-3A wheat globulin is the gene for wheat protein WP5212. [Glo-3A] (Mus musculus) PubMed

 3840.

Results describe wheatwin1 ribonuclease activity in three mutants with altered active sites [wheatwin1]. (Mus musculus) PubMed

 3841.

Recognition of ToxA via Tsn1 triggers transcriptional reprogramming events similar to those reported for avirulence-resistance gene interactions.[Tsn1] (Mus musculus) PubMed

 3842.

Study genetically mapped a TaPHT1.2 transporter, TaPHT1.2-D1, on the long arm of chromosome 4D using a recombinant inbred line derived from Xiaoyan 54 and Jing 411, and isolated a1,302 bp fragment of the TaPHT1.2-D1 promoter from Xiaoyan 54.[PHT1.2] (Mus musculus) PubMed

 3843.

interaction of residues Leu292 of TAXI-IA and Pro294 of TAXI-IIA with the -2 glycon subsite of the xylanase is shown to be critical for both inhibition strength and specificity.[xylanase inhibitor XI-II} (Mus musculus) PubMed

 3844.

The objective of the present study was to characterize IgE epitopes of Tri a 14 and to compare them with those of Pru p 3.[Tri a 14] (Mus musculus) PubMed

 3845.

TM20 transmembrane protein has a polarized distribution within the cell in the most differentiated stages of development [TM20] (Mus musculus) PubMed

 3846.

Maize mutants with a Mu-element insertion in UDPGDH-A or UDPGDH-B were isolated (udpgdh-A1 and udpgdh-B1 respectively) and studied for changes in wall polysaccharide biosynthesis.[UDPGDH-A; UDPGDH-B] (Mus musculus) PubMed

 3847.

functional differentiation of maize LFNR isoenzymes, LFNR1, LFNR2, and LFNR3 [LFNR1, 2, and 3] (Mus musculus) PubMed

 3848.

Conserved and divergent aspects of ZmSCR, the SCARECROW ortholog in Z. mays, are reported.[SCR] (Mus musculus) PubMed

 3849.

Dwarf8 could be involved in maize climatic adaptation through diversifying selection for flowering time [Dwarf8] (Mus musculus) PubMed

 3850.

SsChlI protein variants containing the substitutions identified in the dominant Oy1 maize alleles lack activity necessary for magnesium chelation and confer a semi-dominant phenotype via competitive inhibition of wild-type SsChlI.[SsChlI] (Mus musculus) PubMed

 3851.

In the present study, reactions of maize (Zea mays) (cytokinin dehydrogenase) (CKX) with five different substrates (N6-isopentenyladenine, trans-zeatin, kinetin, p-topolin and N-methyl-isopentenyladenine) were studied. (Mus musculus) PubMed

 3852.

quantitated the distribution of the three maize SUS isoforms across several maize tissues, analyzed their membrane association and investigated novel phosphorylation sites [Sh1; Sus2] (Mus musculus) PubMed

 3853.

analysis of secondary structure and processes of oligomerization of 19 kDa alpha-zein [Z19] (Mus musculus) PubMed

 3854.

Xcl1 is associated with L1 division patterns, hormonal pathways, and meristem maintenance. (Mus musculus) PubMed

 3855.

Expression pattern of ZmPIN1a and ZmPIN1b in the SAM, tassel, and ear of maize [ZmPIN1a and ZmPIN1b] (Mus musculus) PubMed

 3856.

the mop1 RNA-dependent RNA polymerase is required to maintain a threshold level of repeat RNA, which functions in trans to establish and maintain the heritable chromatin states associated with paramutation [mop1] (Mus musculus) PubMed

 3857.

1) Molecular cloning, genomic characterization, and functional expression of the XylT gene is reported. [XylT] 2) Molecular cloning, genomic characterization, and functional expression of the FucT gene is reported.[FucT] (Mus musculus) PubMed

 3858.

The ZmTCRR-1 protein codes for a member of the type-A response regulator class of proteins and is expressed exclusively in the endosperm transfer-cell layer 8-14 days after pollination, when transfer-cell differentiation is most active. (Mus musculus) PubMed

 3859.

The presence of Zea m 1 in the pollen coat and wall suggests that Zea m 1 may play a potential role in pollen germination on the stigma. [Zea m 1 (beta-expansin 1)] (Mus musculus) PubMed

 3860.

A model of expansin action in which EXPB1 facilitates the local movement and stress relaxation of arabinoxylan-cellulose networks within the wall by noncovalent rearrangement of its target, is proposed.[EXPB1] (Mus musculus) PubMed

 3861.

A major quantitative trait locus affecting root traits and leaf abscisic acid concentration was identified in Z. mays and named root-ABA1.[ABA1] (Mus musculus) PubMed

 3862.

TDY1 acts as a sugar sensor to regulate an inducible sugar export pathway as leaves develop under high light conditions. [TDY1] (Mus musculus) PubMed

 3863.

The conservation of a paralogous gene sequence encoding a cytidine deaminase gene over 4.5 million years suggests that Helitrons could add functional gene sequences to new chromosomal positions and thereby create new haplotypes.[cytidine deaminase] (Mus musculus) PubMed

 3864.

The roles of two cytosolic maize glutamine synthetase isoenzymes (GS1), products of the Gln1-3 and Gln1-4 genes, were investigated by examining the impact of knockout mutations on kernel yield.[gs1-3] (Mus musculus) PubMed

 3865.

See2beta has an important role in nitrogenuse and resource allocation under nitrogen limited conditions, and a minor but significant function in the later stages of senescence.[See2] (Mus musculus) PubMed

 3866.

EMP4 is necessary to regulate the correct expression of a small subset of mitochondrial transcripts in the endosperm. [EMP4] (Mus musculus) PubMed

 3867.

Recessive y9 alleles condition accumulation of 9,15,9'-tri-cis-zeta-carotene in dark tissues, such as roots and etiolated leaves. [y9] (Mus musculus) PubMed

 3868.

results support a model whereby Tdy1 acts in the veins to promote Suc export[Tdy1] (Mus musculus) PubMed

 3869.

Random mutagenesis and expression of the maize endosperm AGPase show that the two AGPase subunits are equally predisposed to enzyme activity-altering amino acid changes when expressed in one environment with a single complementary subunit.[AGPase] (Mus musculus) PubMed

 3870.

Ask1 and Ask2 were isolated, cloned, and mapped. [2 genes, Ask1 & Ask2] (Mus musculus) PubMed

 3871.

Cytokinin-binding protein (CBP70) is a transcript elongation factor or a modulator of elongation factor activity specifically mediating a cytokinin-dependent regulation of transcription. (Mus musculus) PubMed

 3872.

NDC80 is a constitutive feature of the central kinetochore [NDC80] (Mus musculus) PubMed

 3873.

Findings suggest that ZmDWF4 may be an ortholog gene of Arabidopsis DWF4 and responsible for brassinolide biosynthesis in maize: ZmDWF4 (Mus musculus) PubMed

 3874.

Thiamine biosynthesis gene thi3 from maize Zea mays has been identified through cloning and sequencing of cDNA and heterologous overexpression of the encoded protein, THI3, in Escherichia coli. (Mus musculus) PubMed

 3875.

A maize clone (thermotolerance 6; TTO6) that seemed to confer elevated heat tolerance in comparison to control cells.[TTO6] (Mus musculus) PubMed

 3876.

The results are consistent with the hypothesis that chloroplast EF-Tu plays a functional role in heat tolerance by acting as a molecular chaperone.[EF-Tu, rca] (Mus musculus) PubMed

 3877.

CBL4 functions in the salt stress-elicited calcium signaling and thus in the tolerance to salinity. [CBL4] (Mus musculus) PubMed

 3878.

The cloning and characterization of the novel maize phosphoethanolamine N-methyltransferase gene (ZmPEAMT1) was reported (ZmPEAMT1) (Mus musculus) PubMed

 3879.

These findings describe a function for the bHLH domain of R in linking transcriptional regulation with chromatin functions by the recruitment of an EMSY-related factor.[R protein] (Mus musculus) PubMed

 3880.

findings show that rmr1 encodes a novel Snf2 protein that affects both small RNA accumulation and cytosine methylation of a proximal transposon fragment at the Pl1-Rhoades allele [rmr1] (Mus musculus) PubMed

 3881.

ZmLOX3-mediated pathway may act as a root-specific suppressor of all three major defense signaling pathways to channel plant energy into growth processes, but is required for normal levels of resistance against nematodes.[ZmLOX3] (Mus musculus) PubMed

 3882.

findings show that variation at the lycopene epsilon cyclase locus alters flux down alpha-carotene versus beta-carotene branches of the carotenoid pathway [lycopene epsilon cyclase] (Mus musculus) PubMed

 3883.

study proposes a model whereby TDY1 and TDY2 function together in a single genetic pathway, possibly in homo- and heteromeric complexes, to promote carbon export from leaves. [Tdy1, Tdy2] (Mus musculus) PubMed

 3884.

The RIK protein may be involved in the maintenance of an inactive chromatin state of knox and possibly other genes in nonmeristematic tissues. (Mus musculus) PubMed

 3885.

Analysis of allele frequencies in a landrace collection supports a key role of Vgt1 in maize altilatitudinal adaptation.[Vgt1] (Mus musculus) PubMed

 3886.

ZmPIN1a is a functional auxin efflux transporter. (Mus musculus) PubMed

 3887.

SDH activity may represent an adaptation to the high-sugar/low-oxygen environment of the endosperm[Iditol 2-Dehydrogenase ] (Mus musculus) PubMed

 3888.

heat tolerance of wheat, and possibly other crop plants, can be improved by modulating expression of plastidal EF-Tu and/or by selection of genotypes with increased endogenous levels of this protein[ EF-Tu ] (Mus musculus) PubMed

 3889.

ZmLsi1 is an influx transporter of Si, which is responsible for the transport of Si from the external solution to the root cells and that ZmLsi6 mainly functions as a Si transporter for xylem unloading. [ZmLsi1; ZmLsi6] (Mus musculus) PubMed

 3890.

Transgenic tobacco plants overexpressing ZmALDH22A1 shows elevated stresses tolerance.[ZmALDH22A1] (Mus musculus) PubMed

 3891.

data suggest that light induction of acetylation on promoter elements of the C4-Pepc gene is controlled by regulating Histone Acetyltransferases activity (C4-Pepc). (Mus musculus) PubMed

 3892.

ATG8 is lipidated during development and in response to nutrient limitations, indicating that autophagy plays a key role in nutrient remobilization. [ATG8] (Mus musculus) PubMed

 3893.

Alignment of respective chromosomal regions of these species via conserved genes allow identification of the pedigree of prolamin gene copies in space and time (Mus musculus) PubMed

 3894.

The loss of mop1 or ts1 function results in increased mRNA levels for several members of the SBP-box gene family.[mop1, ts1] (Mus musculus) PubMed

 3895.

Glycolate Oxidase 1 mutants grow normally under high CO2 conditions, but CO2 assimilation rapidly and linearly diminishes in high light and high O2. [GO1] (Mus musculus) PubMed

 3896.

The proportion of known miRNAs is higher in the mop1-1 mutant relative to wild type and 24-nt siRNA levels are proportionally reduced.(mop1) (Mus musculus) PubMed

 3897.

RNA-dependent RNA polymerase is required for enhancer-mediated transcriptional silencing associated with paramutation at the maize p1 gene (Mus musculus) PubMed

 3898.

TDY1 functions in carbon partitioning by promoting phloem loading. [TDY1] (Mus musculus) PubMed

 3899.

Suppressor of sessile spikelets1 functions in the ra1 branch of the ramosa pathway controlling meristem determinacy. [Sos1] (Mus musculus) PubMed

 3900.

These data indicate that the poor penetrance and expressivity of Ufo1-induced phenotypes is caused by mosaicism of methylation, and progressive mitotic hypomethylation leads to improved meiotic heritability of the mutant phenotype.[Ufo1] (Mus musculus) PubMed

 3901.

Maize AKR4C7 could utilize dl-glyceraldehyde and some pentoses as substrates... Polyclonal antisera raised against AKR4C7 recognized at least three AR-like polypeptides in maize kernels, consistent with the presence of a small gene family. [AKR4C7] (Mus musculus) PubMed

 3902.

The interactions of a mutant maize line (lox3-4, in which ZmLOX3 is disrupted) with the mycotoxigenic seed-infecting fungi Aspergillus flavus and Aspergillus nidulans, was tested.[ZmLOX3] (Mus musculus) PubMed

 3903.

BIF2 phosphorylates ZmPIN1a and regulates its subcellular localization in vivo. [ZmPIN1a] (Mus musculus) PubMed

 3904.

kn1 and td1 function in a pathway to maintain meristem homeostasis but their products may interact with different partners during development.[thick tassel dwarf1 (td1)] (Mus musculus) PubMed

 3905.

DCD1 and ADD1 function in preprophase band formation. [DCD1; ADD1] (Mus musculus) PubMed

 3906.

findings implicate PAN1 in the transmission of an extrinsic signal that polarizes asymmetric subsidiary mother cell divisions toward guard mother cells [PAN1] (Mus musculus) PubMed

 3907.

Lysine-81 and threonine-82 within the I72-T82 region of Glu1 are important for BGAF binding.[BGAF] (Mus musculus) PubMed

 3908.

findings showed that the largest subunit of the presumed maize RNA Polymerase IV is involved in paramutation as well as normal maize development [rmr6, RPD1] (Mus musculus) PubMed

 3909.

Differential expression of LcyB and LcyE mediates carotenoid accumulation and composition. LCYE generates a number of unusual carotenoids when LCYB activity is eliminated. [LycB; lycopene beta-cyclase] (Mus musculus) PubMed

 3910.

The consecutive action of the two starch-related dikinases, the glucan, water dikinase and the phosphoglucan, water dikinase, was studied.[PWD, GWD] (Mus musculus) PubMed

 3911.

Recombinant plant defensin corn 1 (Pdc1) inhibits the growth of Fusarium graminearum. The secondary structure of the recombinant protein was determined. (PDC1; corn EST sequence PCO081743, GenBank accession no. AY109292) (Mus musculus) PubMed

 3912.

The molecular masses of ICL1, ICL2 , and ICL isoforms determined by gel filtration are 164, 207, and 208 kDa, respectively. [ICL1, ICL2] (Mus musculus) PubMed

 3913.

Two related maize proteins, ZmMRPI-1 and ZmMRPI-2 belonging to the C(2)H(2) zinc finger protein family, which interact with ZmMRP-1 and modulate its activity on transfer cell specific promoters, were idenetifed.[BETL1, ZmMRP-1] (Mus musculus) PubMed

 3914.

three-dimensional structure of an m144/beta2-microglobulin (beta2m) complex at 1.9A resolution [m144] (Mus musculus) PubMed

 3915.

the ER environment restricts access of m4/gp34 to K(b); although m4/gp34-K(b) complexes could form when m4 was carried either by MCMV or the adenovirus vector, they were only efficiently exported from the ER in MCMV-infected cells [GP34] (Mus musculus) PubMed

 3916.

IE3 protein, expressed preferentially in glial cells, may play the main role in acute infection. [IE3] (Mus musculus) PubMed

 3917.

Mouse cytomegalovirus (MCMV) molecule fcr-1 promotes a rapid down-regulation of NKG2D ligands murine UL16-binding protein like transcript (MULT)-1 and H60 from the cell surface. (Mus musculus) PubMed

 3918.

findings show that products of the m142 and m143 genes of murine cytomegalovirus together bind dsRNA [m142, m143] (Mus musculus) PubMed

 3919.

These results indicate that m142 and m143 are both required for inhibition of the PKR-mediated host antiviral response.[m142, m143] (Mus musculus) PubMed

 3920.

The crystal structure of the cysteine protease domain of murine cytomegalovirus M48 (M48(USP)) in a complex with a ubiquitin (Ub)-based suicide substrate, is reported. (Mus musculus) PubMed

 3921.

The downregulation of NKG2D ligands by MCMV makes only a small contribution to the impact of m152/gp40 on CTL lysis and only for a small subset of CTL. (Mus musculus) PubMed

 3922.

structural analysis of the murine cytomegalovirus major histocompatibility complex class I-like glycoprotein, m153 (Mus musculus) PubMed

 3923.

Our results suggest that neither ORF is essential for virus replication but m29.1 is important for optimal viral growth in vitro and in vivo.[m29.1] (Mus musculus) PubMed

 3924.

N- and C-terminal regions of M33 as well as known 7TMR signature motifs in transmembrane (TM) II and TM III to determine the impact on cell surface expression, constitutive signaling, and in vivo phenotype were probed.(M33) (Mus musculus) PubMed

 3925.

These results consolidate the role of m38.5 as a viral mitochondrion-localized inhibitor of apoptosis and its functional similarity to the human cytomegalovirus UL37x1 gene product.[m38.5] (Mus musculus) PubMed

 3926.

m157 mutations are predicted to alter the conformation of a putative m157 interface with Ly49H, one that relies on the position of a critical alpha0 helix of m157[ m157 protein] (Mus musculus) PubMed

 3927.

Data show that murine cytomegalovirus arrests cells in G(1) and can also replicate in G(2) cells, due to the cell cycle-independent expression of MCMV immediate-early gene 3. (Mus musculus) PubMed

 3928.

m38.5 associates with Bax, recruits it to mitochondria, and blocks Bax-mediated but not Bak-mediated mitochondrial outer membrane permeabilization. (Mus musculus) PubMed

 3929.

The viral pm142-pm143 multimer interacts with PKR and causes its sequestration in cellular compartments where it is unable to shut off translation and repress viral replication.[pm142 & pm143] (Mus musculus) PubMed

 3930.

The activating Ly49P receptor recognizes cells infected with mouse cytomegalovirus (MCMV) by a process that requires the presence of H2-D(k) and the MCMV m04 protein.[m04] (Mus musculus) PubMed

 3931.

M33 contributes to the efficient establishment or maintenance of long-term latent murine cytomegalovirus infection. [M33] (Mus musculus) PubMed

 3932.

M140 indirectly influences capsid formation in differentiated macrophages by regulating the stability of viral structural proteins.[M140] (Mus musculus) PubMed

 3933.

M33 stimulates CREB transcriptional activity in a phospholipase C-beta and protein kinase C (PKC)-dependent manner. [M33] (Mus musculus) PubMed

 3934.

CpcT is a new phycocyanobilin lyase that specifically attaches phycocyanobilin to Cys-153 of the phycocyanin beta-subunit[CPCT] (Mus musculus) PubMed

 3935.

it is proposed that CcmR (and its associated regulon) represents a specialization for species inhabiting environments subject to fluctuating inorganic carbon concentrations [ccmR] (Mus musculus) PubMed

 3936.

Thus, CpcM is the methyltransferase that modifies the amide nitrogen of Asn71/72 of CpcB, ApcB, and ApcF. (Mus musculus) PubMed

 3937.

LjBGD2 and LjBGD4 preferentially hydrolyzed rhodiocyanoside A and lotaustralin, whereas linamarin was only slowly hydrolyzed [BGD2, BGD4] (Mus musculus) PubMed

 3938.

Nodulin26-like Intrinsic Proteins (NIPs) LjNIP5;1 and LjNIP6;1 from Lotus japonicus are bi-directional As(III) channels [Nodulin26-like Intrinsic Proteins (NIPs) LjNIP5;1 and LjNIP6;1 ] (Mus musculus) PubMed

 3939.

Differences in the C-terminal domains of PCS1 and PCS3 are responsible for their distinct expression levels or stabilities in heterologous systems and patterns of metal activation. [PCS3] (Mus musculus) PubMed

 3940.

LjHb1 overexpression enhances symbiotic nitrogen fixation activity by removing NO as an inhibitor of nitrogenase. [LjHb1] (Mus musculus) PubMed

 3941.

Overexpressing LjCLE-RS1 and -RS2 inhibits nodulation, and suppression depends on HAR1. LjCLE-RS2 expression is strongly up-regulated in roots by nitrate addition. [LjCLE-RS1; LjCLE-RS2] (Mus musculus) PubMed

 3942.

LjSLY1 plays a negative role in nodule formation and overexpression enhances the level of gibberellin signaling. [Sly1] (Mus musculus) PubMed

 3943.

Formation and progression of infection threads into the root cortex were significantly impaired in nap1 and pir1 mutants due to disturbed actin cytoskeleton organization. [nap1;pir1] (Mus musculus) PubMed

 3944.

The brush mutant of Lotus japonicus exhibits a temperature-dependent impairment in nodule, root, and shoot development.[Brush] (Mus musculus) PubMed

 3945.

The isolation and characterization of a hypernodulating mutant of L. japonicus named too much love is reported.[tml] (Mus musculus) PubMed

 3946.

The molecular and biochemical characterization of parvulin-type PPIase family members annotated as LjPar1, LjPar2, and LjPar3 are presented. [3 genes] (Mus musculus) PubMed

 3947.

LjNAS2 was expressed only in nodules, but LjNAS1 was expressed mainly in leaves, stems, and cotyledons[Nicotianamine synthase genes: Nas1 and Nas2] (Mus musculus) PubMed

 3948.

LjINV1 is crucial to whole plant development, but is not essential for nodule formation or function. [LjINV1] (Mus musculus) PubMed

 3949.

The crystal structure of the 3-chlorocatechol 1,2-dioxygenase from the Gram-positive bacterium Rhodococcus opacus (erythropolis) 1CP, specialized in the aerobic biodegradation of 3-chloro- and methyl-substituted catechols, has been solved. (Mus musculus) PubMed

 3950.

Atf1 disruption mutant exhibited triacylglycerols leaky phenotype and accumulated 50 % less fatty acids than the wild-type. [Atf1] (Mus musculus) PubMed

 3951.

X-ray crystallography of the the N1 neuraminidase of the H5N1 avian virus [neuraminidase] (Mus musculus) PubMed

 3952.

ACP binding to human epithelial cell integrins appears to contribute to GBS internalization within epithelial cells. [ACP] (Mus musculus) PubMed

 3953.

A transcription-factor binding motif (TTT-N(6)-ATAT)is required for full ACP expression. [ACP] (Mus musculus) PubMed

 3954.

Pip protein, a proline iminopeptidase gene is upregulated in cabbage by a LuxR homologue and is essential for pathogenicity of Xanthomonas campestris pv. campestris. [Pip, LuxR] (Mus musculus) PubMed

 3955.

Overexpression of the clp gene in Xcc wild-type strain 8004 enhanced the production of XpsE as well as endoglucanase and extracellular polysaccharide (EPS).[Clp, xpsE] (Mus musculus) PubMed

 3956.

The pghAxc genes was identified to encode functional polygalacturonases and could be efficiently induced in planta,and were required for the full virulence of X. campestris pv. campestris to Arabidopsis. (Mus musculus) PubMed

 3957.

The optimum pH and temperature of purified est were 8.0 and 52 degrees C. [Est] (Mus musculus) PubMed

 3958.

VP1U of HBoV has sPLA2-like enzymatic activity, and these residues are crucial for its sPLA2-like activity. (Mus musculus) PubMed

 3959.

Regulation of virB by RyhB (iron responsive small RNA molecule) implicates iron as an environmental factor contributing to the complex regulation of Shigella virulence determinants. [RyhB, VirB] (Mus musculus) PubMed

 3960.

The heme ATP binding cassette (ABC) transporter, ShuUV, of Shigella dysenteriae has been incorporated into proteoliposomes and functionally characterized: [ShuUV] (Mus musculus) PubMed

 3961.

Nonfunctional clyA gene was inactivated either by insertion mutation or frameshift mutation in Shigella strains. (Mus musculus) PubMed

 3962.

The TonB-dependent haem outer membrane transporter ShuA of Shigella dysenteriae bound to heavy atoms was crystallized in several crystallization conditions using detergents.[ShuA] (Mus musculus) PubMed

 3963.

Evidence that a calcium-dependent protein kinase, CDPK3, has an important function in regulating motility of the ookinete in the mosquito midgut (CDPK3). (Mus musculus) PubMed

 3964.

Expression during ookinete development of genes encoding actin, MyoA, and MyoB, was studied and MyoA is only present in fully mature ookinetes, whilst the other two proteins are additionally expressed in gametocytes and zygotes.[Myosin B] (Mus musculus) PubMed

 3965.

we report four new mutations (Y268N, Y268C, L271V and K272R), all in the Qo(2) domain of the cytochrome b gene associated with resistance to atovaquone. [Cytochrome b] (Mus musculus) PubMed

 3966.

a conserved protein HAP2 required for gamete fusion (Mus musculus) PubMed

 3967.

findings show that the rodent malaria parasite gene Plasmodium berghei GENERATIVE CELL SPECIFIC 1 (PbGCS1) plays a central role in its gametic interaction; PbGCS1 knockout parasites show male sterility, resulting in unsuccessful fertilization [GCS1] (Mus musculus) PubMed

 3968.

PbSR is synthesized in macrogametocytes, gets targeted to the crystalloids of developing ookinetes and is involved in crystalloid formation.[PbSR] (Mus musculus) PubMed

 3969.

PbROM1 functions in the invasive stages of parasite development.[rhomboid 1 protease] (Mus musculus) PubMed

 3970.

LISP1-deficient liver-stage parasites do not rupture the membrane of the PV and remain trapped inside hepatocytes.[LISP1] (Mus musculus) PubMed

 3971.

PI3K activity is poised to regulate both adenylyl cyclase activation and adaptation, thereby providing a link to ensure the proper balance of counteracting signals required to maintain optimal chemoresponsiveness [adenylyl cyclase] (Mus musculus) PubMed

 3972.

Results suggest that Trix is specifically involved in a Rho GTPase-signaling pathway that is required for regulation of the actin cytoskeleton during exocytosis [Trix]. (Mus musculus) PubMed

 3973.

Enlazin has roles in cell mechanics and adhesion, and these roles seem to be differentially significant for cytokinesis, depending on the genetic background. (Mus musculus) PubMed

 3974.

identification of a novel gene,Trishanku(triA), by random insertional mutagenesis. TriA is a Broad complex Tramtrack bric-a-brac domain-containing protein,expressed during the late G2 phase of cell cycle and in presumptive spore (prespore (psp)) cells. (Mus musculus) PubMed

 3975.

These results indicate that partial copies of dutA may act upstream of Dd-STATa to regulate tyrosine phosphorylation by an unknown mechanism [STATa]. (Mus musculus) PubMed

 3976.

Results identify a novel vesicle-associated receptor tyrosine kinase-like protein, VSK3, in Dictyostelium discoideum, and demonstrate how VSK3 is involved in phagosome maturation. (Mus musculus) PubMed

 3977.

O2-sensor model of prolyl 4-hydroxylase function was provided in an organism that lacks the canonical HIFalpha transcriptional factor subunit substrate. (Prolyl 4-hydroxylase-1) (Mus musculus) PubMed

 3978.

Poly(ADP-ribose) polymerase inhibition has no deleterious effect on D. discoideum development under oxidative stress (poly(ADP-ribose) polymerase). (Mus musculus) PubMed

 3979.

These results indicate that Dictyostelium G alpha subunit specificity is not limited to receptor coupling and that G alpha subunit sequences outside of the carboxyl terminus are important for cell movement and developmental processes.[G alpha] (Mus musculus) PubMed

 3980.

Inactivation of the iplA gene, the only gene encoding an inositol 1,4,5-trisphosphate receptor (IP3R) in this organism, prevented autophagic cell death.[iplA] (Mus musculus) PubMed

 3981.

hssA gene, whose expression is known to be G-box-binding-factor-dependent and which was specific to prestalk A (pstA) cells is isolated (Mus musculus) PubMed

 3982.

polyketide synthases in Dictyostelium discoideum have roles in biosynthesis of the differentiation regulating factor 4-methyl-5-pentylbenzene-1,3-diol [DiPKS1, DiPKS37] (Mus musculus) PubMed

 3983.

Vacuole membrane protein 1 is an endoplasmic reticulum protein required for organelle biogenesis, protein secretion, and development [vmp1] (Mus musculus) PubMed

 3984.

Dictyostelium discoideum cells secrete CfaD, a protein that is similar to cathepsin proteases (Mus musculus) PubMed

 3985.

Dictyostelium DPYK3 negatively regulates STATc during development in response to DIF-1 signaling.[DPYK3] (Mus musculus) PubMed

 3986.

sibA and sibC are both expressed in vegetative Dictyostelium cells, but the expression of sibC is repressed when cellular adhesion decreases. [SibA, sibC] (Mus musculus) PubMed

 3987.

A structurally dynamic model for nucleotide- and actin-induced closure of the actin-binding cleft of myosin, based on site-directed spin labeling and electron paramagnetic resonance (EPR) in Dictyostelium myosin II, is presented.[Myosin II] (Mus musculus) PubMed

 3988.

Dictyostelium CblA protein regulates STAT signalling via a tyrosine phosphatase [CblA] (Mus musculus) PubMed

 3989.

The identification of homolog of Saccharomyces cerevisiae RPB4 in D. discoideum was reported. (Mus musculus) PubMed

 3990.

Cyclase associated protein (CAP) acts at multiple crossroads in Dictyostelium discoideum AX2 and links signaling pathways to the actin cytoskeleton either by physical interaction with cytoskeletal components or through gene expression regulation [CAP] (Mus musculus) PubMed

 3991.

[differentiation-inducing factor DIF-1] (Mus musculus) PubMed

 3992.

In wild-type slugs, the expL7 promoter was activated in the anterior tip region, but downrgulated in Dd-STATa-null slugs [ExpL7] (Mus musculus) PubMed

 3993.

Altered morphogenesis and the cell-sorting defect of rapGAP3(-) cells may result in reduced directional movement of the mutant cells to the apex of the mound.[RapGap3] (Mus musculus) PubMed

 3994.

Kif9 maintains a connection between the microtubule-organizing center and nucleus during interphase and Kif6 is essential for viability. [Kif6, Kif9] (Mus musculus) PubMed

 3995.

Expression of the C-terminal fragment from the endogenous 34-kDa actin-binding protein of Dictyostelium discoideum leads to the formation of actin inclusions in vivo. [actin binding protein] (Mus musculus) PubMed

 3996.

Reg is localized to the nucleus and is present in growing as well as starving Dictyostelium cells. [Reg] (Mus musculus) PubMed

 3997.

CenB knockout cells exhibited aberrant nuclear architecture, characterized by enlarged and deformed nuclei and loss of centrosome-nucleus anchoring. [CenB] (Mus musculus) PubMed

 3998.

PTEN is a mechanosensing signal transducer for myosin II localization in Dictyostelium cells (Mus musculus) PubMed

 3999.

MhcA localizes to the posterior cell cortex and provides the contractile force for translocation of the cell body. [mhcA] (Mus musculus) PubMed

 4000.

Purified recombinant ArnT protein was shown to be highly alpha-helical as determined by circular dichroism analysis. (L-Ara4N transferase protein ArnT) (Mus musculus) PubMed

 4001.

Production of recombinant SplB and SplC proteases in Escherichia coli, together with structural and functional characterization of the purified enzymes.[splb, splc] (Mus musculus) PubMed

 4002.

Inactivation of SarA in 8325-4 increases repression of Hla and depends on reduced expression of SarS, whereas in strain V8, inactivation of SarA decreases repressor activity and, therefore, enhances Hla transcription. [SarA, Hla, SarS] (Mus musculus) PubMed

 4003.

These results suggest that the cvfB gene product contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways.[cvfB] (Mus musculus) PubMed

 4004.

The data indicate that the expression of rot transcription is significantly repressed only by SarA. [SarA] (Mus musculus) PubMed

 4005.

These results indicate that svrA does not play a role in Staphylococcus aureus infections via an agr-mediated pathway.[svrA] (Mus musculus) PubMed

 4006.

It was concluded that the fibrillar nature of SasG explains its ability to mask binding of S. aureus microbial surface components recognizing adhesive matrix molecules to their ligands and to promote formation of biofilm.[SasG] (Mus musculus) PubMed

 4007.

Complementation studies show that a putative ribitol phosphate polymerase, TarL, catalyzes both the addition of the priming ribitol phosphate onto the linkage unit and the subsequent polymerization of the polyribitol chain.[TarL] (Mus musculus) PubMed

 4008.

Ebh might contribute to structural homeostasis by forming a bridge between the cell-wall and cytoplasmic membrane to avoid plasmolysis under hyperosmotic condition.(Ebh) (Mus musculus) PubMed

 4009.

This is the first report of the direct observation of an Ebh structure containing a large number of repeating units, although structures containing one, two, or four repeating units have been reported. (Ebh) (Mus musculus) PubMed

 4010.

LigA was found to be essential in vitro and in vivo and TarI was found to be essential in vitro but not in vivo. {ligA, TarI] (Mus musculus) PubMed

 4011.

The results indicate that SarZ may be an important regulator governing the dissemination phase of S. aureus infections, as it promotes toxin expression while repressing factors required for biofilm formation. (Mus musculus) PubMed

 4012.

These results show that rbf is an activator of biofilm formation in different strains of S. aureus, although the degree of activation varies among strains.[Rbf] (Mus musculus) PubMed

 4013.

This study shows that SasG-A domain contributes to intercellular autoaggregation by homo-oligomerization, and that may facilitate the adherence to host-tissues in the infection of S. aureus.(SasG) (Mus musculus) PubMed

 4014.

Inactivation of gdpS results in an alteration in the production of a range of virulence factors, such as serine and cysteine proteases, fibrinogen-binding proteins, and, specifically, protein A (Spa), a major surface protein of S. aureus.[GdpS] (Mus musculus) PubMed

 4015.

analysis of Staphylococcus aureus AgrD residues required for autoinducing peptide biosynthesis [AgrD] (Mus musculus) PubMed

 4016.

Our results are consistent with a model wherein rbf represses synthesis of icaR, which in turn results in derepression of icaADBC and increased PNAG production; rbf controls expression of an unknown factor(s) that represses icaR [rbf] (Mus musculus) PubMed

 4017.

gARID1 is an important transactivator in regulation of the Giardia cwp1 gene, which is key to Giardia differentiation into cysts [gARID1 and cwp1] (Mus musculus) PubMed

 4018.

These results suggest that G. lamblia possesses phospholipases, PLA A1 and PLA A2 isoforms that may be soluble or associated with membranes. [PLA A1, PLA A2] (Mus musculus) PubMed

 4019.

The full length variant-specific surface antigen gene, vsp752, from the isolate of G. lamblia has the common characteristics with other previously identified VSPs. [vsp752] (Mus musculus) PubMed

 4020.

The glOTC crystal contains one protein molecule in the asymmetric unit and the crystallographic 3-fold symmetry generates a trimeric structure, consistent with the association state measured in solution (vide supra). [OTC] (Mus musculus) PubMed

 4021.

Using a reverse genetics approach, the report demonstrate that the tryptophan aminotransferase Tam1 catalyses pigment biosynthesis by conversion of tryptophan into indolepyruvate [Tam1] (Mus musculus) PubMed

 4022.

Study reports the identification and characterization of the Cys(2)His(2)-type zinc finger protein Mzr1 that functions as a transcriptional activator during host colonization. [Mzr1] (Mus musculus) PubMed

 4023.

demonstrate that Khd4 recognizes the sequence AUACCC in vivo via its tandem KH domains 3 and 4.[Khd4] (Mus musculus) PubMed

 4024.

This is the first reported Entamoeba PAK member that contains a N-terminal pleckstrin homology domain and a highly conserved Cdc42/Rac interacting binding domain. [PAK2] (Mus musculus) PubMed

 4025.

These findings clearly suggest that the 29-kDa protein of E. histolytica has a role in both survival of trophozoites in the presence of reactive oxygen species and pathogenesis of amoebiasis. (Mus musculus) PubMed

 4026.

These data indicate that the two Rab7 isotypes play distinct but co-ordinated roles in lysosome and phagosome biogenesis.[Rab7A, Rab7B] (Mus musculus) PubMed

 4027.

These results indicate that in addition to cytoskeletal association, EhLimA may also associate with lipid rafts in the parasite plasma membrane (EhLimA). (Mus musculus) PubMed

 4028.

KERP1 was also seen to be a virulence marker as trophozoites affected in kerp1 expression by an antisense strategy were unable to form liver abscesses.[KERP1] (Mus musculus) PubMed

 4029.

Downregulation of EhMLBP using antisense technology resulted in trophozoites with impaired growth and cytopathic activity, indicating that EhMLBP is an essential protein.[MLBP] (Mus musculus) PubMed

 4030.

CrzA is an important downstream effector of calcineurin that controls morphology in A. fumigatus. [CrzA] (Mus musculus) PubMed

 4031.

Ace2 is a factor that is essential for normal conidiation, cell wall architecture and pigment production. [Ace2] (Mus musculus) PubMed

 4032.

These results showe that the mitochondrial copy number is reduced in the DeltacalA mutant strain, and the mutant has increased alternative oxidase (aoxA) mRNA accumulation and activity. .[CalA] (Mus musculus) PubMed

 4033.

The LmjF01.0030 gene of Leishmania major Friedlin, annotated as 'MCAK-like', was confirmed as a kinesin with an internally located motor domain and termed LmjKIN13-1.(LmjKIN13-1) (Mus musculus) PubMed

 4034.

Genome sequence of Leishmania major revealed two genes coding for two isoforms of SHMT the short form was found in the cytosol while the long one was found in an organelle that has hallmarks of the parasite mitochondrion. [Serine hydroxymethyltransferase] (Mus musculus) PubMed

 4035.

Detailed kinetic studies comparing TDPX1 and TryP1 showed that both enzymes obey saturation ping-pong kinetics and both enzymes show high affinity for tryparedoxin and broad substrate specificity for hydroperoxides (TDPX1 and TryP1). (Mus musculus) PubMed

 4036.

These data support the hypothesis that ISP2 and 3 of L. major target host serine peptidases and influence the early stages of infection of the mammalian host.[ISP2 & ISP3] (Mus musculus) PubMed

 4037.

DHCH1 is an essential gene with NADP(+)-dependent methylene tetrahydrofolate DH and 5,10-methenyltetrahydrofolate CH activities. [DHCH1] (Mus musculus) PubMed

 4038.

Despite the fact that dihydroxyacetonephosphate acyltransferase is important for virulence the null mutant still exhibited the typical characteristics of metacyclics.[ dihydroxyacetonephosphate acyltransferase] (Mus musculus) PubMed

 4039.

GT78 is a novel UDP-galactose:fucoside alpha3-galactosyltransferase that modifies Skp1 in the cytoplasm of Dictyostelium (Mus musculus) PubMed

 4040.

Ile(104) substitutions perturb the equilibrium between inactive and active cAR1 conformations in favour of the latter. (cAR1) (Mus musculus) PubMed

 4041.

study shows by single-molecule microscopy an agonist-induced increase in mobile fraction of cAMP-receptor at the leading edge of chemotacting Dictyostelium; onset of receptor mobility was correlated to uncoupling & activation of Galpha2-protein [cAR1] (Mus musculus) PubMed

 4042.

Inactivation of dupA resulted in depressed L. pneumophila growth and sustained hyperphosphorylation of ERK1. [Erk1, DupA] (Mus musculus) PubMed

 4043.

These results suggest that Dictyostelium utilises a distinct Xpf nuclease-mediated repair process to remove crosslinked DNA.[Xpf, Rev3] (Mus musculus) PubMed

 4044.

SAP1 is essential for liver infection possibly by controlling the expression of infectivity-associated parasite effector genes. [Sap1] (Mus musculus) PubMed

 4045.

we characterized two respiratory dehydrogenases, succinate:ubiquinone reductase (complex II) and alternative NADH dehydrogenase (NDH-II),in Plasmodium yoelii yoelii (Mus musculus) PubMed

 4046.

analysis of CYP51 from Trypanosoma cruzi (Mus musculus) PubMed

 4047.

Here we report the identification and characterization of TcrPDEA1, a singular phosphodiesterase of T. cruzi which is resistant to the typical phosphodiesterase inhibitors, such as IBMX, papaverine and theofylline.[TcrPDEA1] (Mus musculus) PubMed

 4048.

The precise temporal expression of the T. cruzi-specific protein Met-III is reported.[Met-III] (Mus musculus) PubMed

 4049.

In this study, the metacaspases, MCA3 and MCA5 were expressed and indirect evidence of their participation in programmed cell death was obtained, induced by fresh human serum. [Metacaspase 3, Metacaspase 5] (Mus musculus) PubMed

 4050.

identified parvulin TcPIN1 (parvulin peptidyl-prolyl cis/trans isomerase)as a homolog of the human hPin1 PPI. [PIN1] (Mus musculus) PubMed

 4051.

Recombinant T. cruzi Protein geranylgeranyltransferase type I (PGGT-I) showed activity with distinct specificity toward the C-terminal CaaX motif of protein substrates. [PGGT-I] (Mus musculus) PubMed

 4052.

TcMCP-1 is a metallocarboxypeptidase with a catalytic metal ion in the active site. [TcMCP-1] (Mus musculus) PubMed

 4053.

Trypanosoma have a conserved Mago and a divergent Y14 protein. [Y14] (Mus musculus) PubMed

 4054.

The G5 domain of aap dimerizes in the presence of Zn(2+), incorporating 2-3 Zn(2+) ions in the dimer interface for biofilms[aap protein] (Mus musculus) PubMed

 4055.

The activation and aminoacylation properties of D. hafniense Pyrrolysyl-tRNA synthetase and the nature of the pyrrolysine tRNA identity elements were determined (Pyrrolysyl-tRNA synthetase). (Mus musculus) PubMed

 4056.

binding of a potent effector molecule to reduced CprK1 induces local changes in the N-terminal effector binding domain[CprK1] (Mus musculus) PubMed

 4057.

The apo 2.1A resolution structure of the intact D. hafniense pyrrolysyl-tRNA synthetase (PylS)was reported. (PylS) (Mus musculus) PubMed

 4058.

The transcriptional regulator CprK induces expression of halorespiratory genes and is reversibly inactivated by oxygen. [CprK] (Mus musculus) PubMed

 4059.

Desulfitobacterium hafniense PylRS-tRNA(Pyl) is an orthogonal pair in vitro and in vivo, and present the crystal structure of this orthogonal pair [Pyrrolysyl-tRNA synthetase] (Mus musculus) PubMed

 4060.

Cel5G, Cel5H, and Cel5J were identified as processive endoglucanases acting on the beta-1,4 bonds linking cellobiose units in cellulose degradation. [Cel5G, Cel5H, Cel5J] (Mus musculus) PubMed

 4061.

on the basis of the data, Glutamate-134 is intrinsically involved in the hydrolysis reaction catalyzed by DapE and likely plays the role of a general acid and base [DapE] (Mus musculus) PubMed

 4062.

sequence-activity relationships and key residues of porin P2 Loop 7 were identified; ability of mutant peptides to induce activation of signal transduction pathways and release of TNF-alpha and IL-6 has been determined [porin P2] (Mus musculus) PubMed

 4063.

all TpsB proteins have a modular structure, with a periplasmic domain that interacts with the cognate TpsA protein and with pore forming activity contained within the C terminus[HMW1B] (Mus musculus) PubMed

 4064.

Results present the crystal structure of the C-terminal end of Hia, corresponding to the entire Hia translocator domain and part of the passenger domain (residues 992-1098). (Mus musculus) PubMed

 4065.

The structure of SiaP in the presence of the sialic acid analogue 2,3-didehydro-2-deoxy-N-acetylneuraminic acid reveals the ligand bound in a deep cavity with its carboxylate group forming a salt bridge with a highly conserved Arg residue [SiaP] (Mus musculus) PubMed

 4066.

isolated and characterized biophysical properties of HI1462 in relation to TolC in E coli. [HI1462] (Mus musculus) PubMed

 4067.

study concludes that the NTHi vapBC-1 gene pair functions as a classical Toxin-antitoxin locus and that the induction of VapC-1 RNase activity leads to growth inhibition via the mechanism of mRNA cleavage[VapB-1 and VapC-1] (Mus musculus) PubMed

 4068.

Results demonstrate that mutation of the invariant glycine (G418A) within motif 2 led to attenuated transport activity, while mutation of the invariant glycine (G155A/V/E) within motif 1 had no discernible effect on activity [FbpA, FbpB, FbpC] (Mus musculus) PubMed

 4069.

The recognition site for the Mod methyltransferase in H. influenzae is 5'-CGAAT-3' (mod). (Mus musculus) PubMed

 4070.

In the current study, examination of purified HMW1B by size exclusion chromatography and negative staining electron microscopy revealed that the predominant species was a dimer.[HMW1B] (Mus musculus) PubMed

 4071.

In this study, we identified SiaR as a repressor of sialic acid transport and catabolism in nontypeable Haemophilus influenzae.[SiaR] (Mus musculus) PubMed

 4072.

An extensive secondary structure at the 5' end of sxy mRNA sequesters the ribosome-binding site and start codon in a stem-loop (sxy). (Mus musculus) PubMed

 4073.

In a collection of NTHI strains we found several strains in which there were two distinct but variant lic1D DNA sequences, genes predicted to encode the transferase responsible for directing the addition of PCho to LPS.[Lic1D] (Mus musculus) PubMed

 4074.

data strongly suggest that the mechanism of phosphotransfer in the uridyltransferase reaction in GlmU is primarily through an associative mechanism with a pentavalent phosphate intermediate and an inversion of stereochemistry [GlmU] (Mus musculus) PubMed

 4075.

In conclusion, we have discovered a novel non-typable Haemophilus influenzae outer membrane protein, protein E, with adhesive properties.[protein E in strain 772] (Mus musculus) PubMed

 4076.

results indicate that dsbA is required in vivo and that HbpA and additional DsbA-dependent factors are likely to participate in H. influenzae pathogenesis [dsbA] (Mus musculus) PubMed

 4077.

Aspartate 139 in the active site of serine acetyltransferase, in dyad linkage with histidine154, likely facilitates catalysis by increasing the basicity of His154; aspartate139 may also play a role during the catalytic reaction. (serine acetyltransferase) (Mus musculus) PubMed

 4078.

HMW1 is a glycoprotein with an unusual N-linked carbohydrate modification; its glycosylation requires a glycosyltransferase with a novel activity (Mus musculus) PubMed

 4079.

catalytic and structural properties of the H67A and H349A dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) from Haemophilus influenzae were investigated [DapE] (Mus musculus) PubMed

 4080.

mucosal immunization of mice with rP2 induces antibodies that recognize surface exposed epitopes on multiple strains, indicating that P2 is a candidate for development of a mucosal vaccine for nontypeable Haemophilus influenzae[OMP P2 ] (Mus musculus) PubMed

 4081.

The results suggest that BtuCD as a prototype type II ABC importer may have a mechanism that is distinct from that of ABC exporters such as Sav1866 or type I ABC importers such as those specific for molybdate (ModBC) or maltose (MalFGK). (BtuCD) (Mus musculus) PubMed

 4082.

data suggest that the ubiquitous adhesin protein E plays an important role in the pathogenesis of nontypeable Haemophilus influenzae infection [adhesin protein E] (Mus musculus) PubMed

 4083.

Here we describe the structure of YfeU and discuss the possible function as an etherase possibly involved in peptidoglycan recycling. (Mus musculus) PubMed

 4084.

Canadian beta-lactamase-negative Haemophilus influenzae isolates were found to have the N526K mutations in their ftsI genes, and their ampicillin MIC(50) values were 4-8 times that of beta-lactamase-negative ampicillin-susceptible strains [ftsI] (Mus musculus) PubMed

 4085.

The first structure of a member of the immunoglobulin A protease family at 1.75-A resolution was reported. (IgAP1) (Mus musculus) PubMed

 4086.

Haemophilus influenzae beta-carbonic anhydrase is an allosteric enzyme that can adopt active and inactive conformations, the latter of which is stabilized by bicarbonate ion binding to a non-catalytic site. (beta-carbonic anhydrase). (Mus musculus) PubMed

 4087.

YbaB was demonstrated to be a DNA-binding protein (YbaB) (Mus musculus) PubMed

 4088.

findings revealed that MADS1 played a role in specifying lemma and palea and acted as a repressor of overdevelopment of lemma and palea; it was indicated that MADS1 upregulated the transcript level of AP3 homologue MADS16 [MADS1, MADS16] (Mus musculus) PubMed

 4089.

EUI1 plays a negative role in gibberellin-mediated regulation of cell elongation in the uppermost internode of rice [EUI1] (Mus musculus) PubMed

 4090.

results suggest that gibberellin modulates the activity of mitochondrial pyruvate dehydrogenase by regulating PDK1 expression and subsequently controlling plant growth and development [OsPDK1] (Mus musculus) PubMed

 4091.

results supply genetic evidence that a plant Glu receptor-like gene, rice GLR3.1, is essential for the maintenance of cell division and individual cell survival in the root apical meristem at the early seedling stage [GLR3.1] (Mus musculus) PubMed

 4092.

The GOLD HULL AND INTERNODE2 (GH2) gene in rice encodes a cinnamyl-alcohol dehydrogenase (CAD) functioning to synthesize coniferyl and sinapyl alcohol precursors in rice lignin biosynthesis. (Mus musculus) PubMed

 4093.

first time that the function of a rice UGT has been characterized [UGT5] (Mus musculus) PubMed

 4094.

only one member of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHPS1) family expresses in close correlation with phenylalanine ammonialyase [DAHPS1] (Mus musculus) PubMed

 4095.

These results suggest that OsPPT1a is a functional p-hydroxybenzoate polyprenyltransferase (PPT) involved in ubiquinone (UQ) biosynthesis in Oryza sativa [OsPPT1a]. (Mus musculus) PubMed

 4096.

Three of the four major clades of GSKs present in Arabidopsis and rice were established early in the evolutionary history of extant seed plants. (Mus musculus) PubMed

 4097.

The rice genome has 4 RAD21-like genes that share lower than 21% identity at polypeptide levels, and each is present as a single copy in this genome.[OsRAD21-24] (Mus musculus) PubMed

 4098.

findings show that human selection of an amino acid substitution in the predicted DNA binding domain encoded by sh4, a gene of previously unknown function, was primarily responsible for the reduction of grain shattering in rice domestication [sh4] (Mus musculus) PubMed

 4099.

characterization of the rice leafy-head2 (lhd2) mutant that exhibits shortened plastochron, dwarfism, reduced tiller number, and failure of phase transition from vegetative to reproductive growth[leafy head2] (Mus musculus) PubMed

 4100.

The modified GLP-1 (mGLP-1) gene was enlarged to 5xmGLP-1 (mGLPx5) by tandem repeat. Endoplasmic reticulum (ER) is a suitable intracellular organelle for accumulation of mGLPx5 peptide [GLP-1]. (Mus musculus) PubMed

 4101.

OsIAA3 is one of the IAA gene family members whose expression is rapidly increased in response to auxin; results suggest that, in rice, auxin is important for development and its signaling is mediated by IAA genes [IAA3] (Mus musculus) PubMed

 4102.

This gene is probably a new excessive tillering gene in rice and is designated tentatively ext-M1B (t). (Mus musculus) PubMed

 4103.

results show that, at both a transcriptional and a transductional level, OsFK1 is preferentially expressed under aerobic conditions, whereas OsFK2 is induced under anoxia [FK1 & FK2] (Mus musculus) PubMed

 4104.

These revealed high expression levels of the reporter genes directed by the rsus3 promoter in guar endosperm.[sucrose synthase] (Mus musculus) PubMed

 4105.

Nuclear ACR7 interacts with nucleocytoplasmic HSP18.0-CII in vivo. The potential ability of nuclear protein ACR7 to bind Gln and the possibility of the protein acting as a Gln sensor in rice leaves is discussed [ACR7]. (Mus musculus) PubMed

 4106.

The full-length cDNA (3612 bp) of OsNHA1 was cloned by RT-PCR approach from rice (Oryza sativa L.), which encodes a putative plasma membrane Na+/H+ antiporter. (Mus musculus) PubMed

 4107.

Four alternative transcripts of OsFCA were cloned from the leaves of rice, and designated as OsFCA-1, OsFCA-2, OsFCA-3 and OsFCA-4 respectively. OsFCA-1 was homologous to FCA-gamma of Arabidopsis (Mus musculus) PubMed

 4108.

A novel blast-inducible RING-H2 type zinc finger protein gene OsRING-1 was cloned from rice by cDNA library screening. (Mus musculus) PubMed

 4109.

Cloning, characterization and tissue-specific expression of a putative EMBRYONIC FLOWER 2 (EMF2) gene in Oryza sativa. (Mus musculus) PubMed

 4110.

The isolation and characterization of BTH-Induced MAP Kinase 2 (BIMK2) is reported. [BIMK2] (Mus musculus) PubMed

 4111.

Oscry1s are responsible for regulating blue light-mediated de-etiolation in rice. OsCRY2 is involved in the flowering time in rice [OsCRY1 and OsCRY2]. (Mus musculus) PubMed

 4112.

Expression patterns for PPCK1, PPCK2, and PPCK3 genes in rice are discussed. [PPCK1][PPCK2][PPCK3] (Mus musculus) PubMed

 4113.

A rice cDNA encoding a putative arginine decarboxylase (ADC) protein, a key enzyme involved with putrescine (Put) biosynthesis in plants was cloned and characterized.[ADC1] (Mus musculus) PubMed

 4114.

Mutations in the Rymv1 gene are associated with resistance to Rice yellow mottle virus. [Rymv1] (Mus musculus) PubMed

 4115.

Treatment of seedlings with a histone deacetylase (HDAC) inhibitor, trichostatin A, increased acetylation of histones H3 and association of RNA polymerase II on the ADH1 and PDC1 loci, thereby increasing transcript levels of ADH1 and PDC1 [ADH1 and PDC1]. (Mus musculus) PubMed

 4116.

OsDOS is a novel nuclear protein that delays leaf senescence likely, at least in part, by integrating developmental cues to the JA pathway. (Mus musculus) PubMed

 4117.

isolated a Lon protease gene, OsLon1, from Oryza sativa; the OsLon1 gene was successfully expressed in E. coli and the detected protein size, about 120 kDa, matched the expected molecular mass of the His-tagged OsLon1 protein (Mus musculus) PubMed

 4118.

OsEIL1 is involved in ethylene signal transduction pathway and acts as a positive regulator of ethylene response in rice. (Mus musculus) PubMed

 4119.

1:PEX5L, a splice variant of the type I peroxisomal targeting signal (PTS1) receptor, is cloned and characterized. [PEX5L] 2:PEX5S, a splice variant of the type I peroxisomal targeting signal (PTS1) receptor, is cloned and characterized. [PEX5S] (Mus musculus) PubMed

 4120.

GAMYB, GAMYBL1, and GAMYBL2 are regulated by microRNA miR159 in flowers. [GAMYB, GAMYBL1, and GAMYBL2] (Mus musculus) PubMed

 4121.

Xanthomonas oryzae pv. oryzae commandeers the regulation of otherwise developmentally regulated host genes to induce a state of disease susceptibility [Os8N3] (Mus musculus) PubMed

 4122.

There are synergistic interactions between RISBZ1 and RPBF involved in the recognition of a GCN4 target motif TGA(G/C)TCA. [RPBF]& [RISBZ1] (Mus musculus) PubMed

 4123.

RPP10 is encoded by a single gene and has high homology to acyl-CoA-binding proteins from other plants. (Mus musculus) PubMed

 4124.

Salicylic Acid and NaCl are inducers for pib promoter. [pib] (Mus musculus) PubMed

 4125.

Xa21 mediated the disease resistance against Xanthomonas oryzae pv. oryzae. [Xa21] (Mus musculus) PubMed

 4126.

cloning of the cDNA of FY; results indicate that the autonomous flowering pathway is present in monocots, and the regulation through FY and FCA interaction is conserved between monocots and dicots [FY, FCA] (Mus musculus) PubMed

 4127.

CEBiP plays a key role in the perception and transduction of chitin oligosaccharide elicitor in the rice cells[CEBiP] (Mus musculus) PubMed

 4128.

Green rice leafhopper resistance 5 (Grh5) is located on the distal region of the long arm of chromosome 8 and tightly linked to the simple sequence repeat markers RM3754 and RM3761. (Mus musculus) PubMed

 4129.

Identification of Ala(111), Gly(123) and Ser(127)as key amino-acids in OsCaM61 that play a vital role in suitable changes of rice calmodulin-binding kinase conformation for kinase activation (OsCaM61). (Mus musculus) PubMed

 4130.

isolateion & identification of a full-length cDNA, OsBISAMT1 which encodes a putative S-adenosyl-L: -methionine:salicylic acid carboxyl methyltransferase; it may be involved in disease resistance responses as well as in wound response in rice [BISAMT1] (Mus musculus) PubMed

 4131.

IRO2 is involved in the regulation of gene expression under Fe-deficient conditions. [IRO2] (Mus musculus) PubMed

 4132.

Gamma-Aminobutyrate transaminase (GABA-T)expression is induced by blast fungus infection, mechanical wounding and ultraviolet radiation in rice leaves and is not detected in normal rice organs. (Mus musculus) PubMed

 4133.

The isolation and physical mapping of tms5 (thermosensitive genic male sterile 5) in in 3 rice populations are reported.[tms5] (Mus musculus) PubMed

 4134.

identification of a cluster of three genes at the Sub1 locus, encoding putative ethylene response factors [Sub1A] (Mus musculus) PubMed

 4135.

The MYBGA-GA Response Element interaction affects sugar feedback control in balanced energy production during seedling growth. [MYBGA] (Mus musculus) PubMed

 4136.

These data suggest that SNAC1 holds promising utility in improving drought and salinity tolerance in rice.[Snac1] (Mus musculus) PubMed

 4137.

The expression pattern of OSBZ8 directly correlates with the ability of the rice cultivar to tolerate salt stress (OSBZ8). (Mus musculus) PubMed

 4138.

Sugar specificities of class III (OsChib1a) and class I (OsChia1cDeltaChBD) from Oryza sativa L.were investigated by nuclear magnetic resonance spectra of the enzymatic products from partially N-acetylated chitosans.(OsChib1a)(OsChia1cDeltaChBD) (Mus musculus) PubMed

 4139.

RIP1 is probably a nuclear protein that may form a functional complex with other proteins and carry out essential cellular and developmental roles during the late stage of pollen formation. (Mus musculus) PubMed

 4140.

The isolation and characterization of three floral organ number4 (fon4) alleles and the cloning of the FON4 gene in O. sativa is reported.[fon4] (Mus musculus) PubMed

 4141.

The comparatively broader substrate range of this EGase with respect to beta-1,4-glycan backbones (glucose and xylose) may partly reflect different roles of gramineous and non-gramineous GHF9 enzymes.[EGase] (Mus musculus) PubMed

 4142.

OsCel9A reveals a broad substrate specificity with respect to sugar backbones (glucose and xylose) in beta-1,4-glycans of type II cell wall. (Mus musculus) PubMed

 4143.

FON2 transcripts are localized at the apical region in all meristems in the aerial parts of rice plants, showing an expression pattern similar to that of Arabidopsis CLV3 [FON2]. (Mus musculus) PubMed

 4144.

data suggest that OsAGAP has a specific role in regulating vesicle trafficking pathways such as the auxin influx pathway, which in turn controls auxin-dependent root growth in plants [AGAP] (Mus musculus) PubMed

 4145.

results indicate that a single amino acid in the xxLxLxx motif may be critical for maintaining the recognition surface of Pi2 and Piz-t to their respective avirulence proteins [Pi2 and Piz-t] (Mus musculus) PubMed

 4146.

Results showed that the expression level of rice UDT1 and GAMYB were reduced in msp1-4, implying that UDT1 and GAMYB are possibly the downstream genes of MSP1 gene in rice pollen development: [UDT1, GAMYB] (Mus musculus) PubMed

 4147.

Study describes the cloning and identification of a rice cDNA, OsTVLP1, encoding a protein with similarity to TGF-beta receptor interacting proteins and vacuolar assembly Vam6p/Vps39p proteins. [TVLP1 protein] (Mus musculus) PubMed

 4148.

1) Expression of PBZ1 is regulated by gibberellic acid signalling and stress stimuli. [PBZ1] 2)GID1 is involved in tolerance to cold stress and resistance to blast fungus. [GID1] (Mus musculus) PubMed

 4149.

cloning of OsAtg4 and OsAtg8 from Oryza sativa; detected their expression patterns in various tissues[OsAtg4]& [OsAtg8] (Mus musculus) PubMed

 4150.

OsHKT1, OsHKT2, and OsVHA confer salt tolerance by maintaining a low cytosolic Na(+) level and a correct ratio of cytosolic Na(+)/K(+). [OsHKT1, OsHKT2, and OsVHA] (Mus musculus) PubMed

 4151.

Complementation analyses for HTD1 confirm that the defect in HTD1 is responsible for both high-tillering and dwarf phenotypes in the htd1 mutant; HTD1 is an ortholog of MAX3 in A. thaliana.[HTD1] (Mus musculus) PubMed

 4152.

OsSUT1 is present in the companion cells and sieve elements of the scutellar vascular bundle, where it may have a role in phloem loading of sucrose for transport to the developing shoot and roots. (Mus musculus) PubMed

 4153.

These results indicate that TDR is a key component of the molecular network regulating rice tapetum development and degeneration.[TDR] (Mus musculus) PubMed

 4154.

The characterization of a T-DNA insertional mutant in the Wax-deficient anther1 (Wda1) gene of rice (Oryza sativa), which shows significant defects in the biosynthesis of very-long-chain fatty acids in both layers, is reported.[Wda1] (Mus musculus) PubMed

 4155.

The isolation and characterization of salt overly sensitive 1 (SOS1) in O. sativa is reported. (Mus musculus) PubMed

 4156.

These results indicate that Xb3 is necessary for full accumulation of the XA21 protein and for Xa21-mediated resistance.[XB3] (Mus musculus) PubMed

 4157.

The albino trait was controlled by a single recessive gene that's tantatively referred to as al12. [al12] (Mus musculus) PubMed

 4158.

Fluorescence investigations of phytochrome (phy) in rice (Oryza sativa L. cv. Nipponbare) mutants deficient in phyA, phyB and phyA plus phyB were performed [phyA] (Mus musculus) PubMed

 4159.

Secretory carrier membrane protein 1 (SCAMP1) localizes to the early endosome. [SCAMP1] (Mus musculus) PubMed

 4160.

Study shows that the seed shattering is controlled by a single dominant gene, Shattering1 (SHA1), encoding a member of the trihelix family of plant-specific transcription factors. [SHA1 protein] (Mus musculus) PubMed

 4161.

YABBY1 is involved in regulating the differentiation of a few specific cell types and is unrelated to polar regulation of lateral organ development [YABBY1] (Mus musculus) PubMed

 4162.

The isolation and characterization of Lti6b in rice is reported.[Lti6b] (Mus musculus) PubMed

 4163.

results demonstrated that the Rcn1 gene was not involved in the D3-associated pathway in tillering control [RcnI, D3] (Mus musculus) PubMed

 4164.

NADP-ME2 has a role in enhancing tolerance of plants to salt and osmotic stress. [NADP-ME2] (Mus musculus) PubMed

 4165.

SET Domain Group Protein 714 (SDG714) is involved in DNA methylation, the transposition of transposable elements, and genome stability in rice. [SDG714] (Mus musculus) PubMed

 4166.

Expression of Lsi1 is required for the transport of Si through the cells of the exodermis and endodermis, is regulated by abscisic acid and displays a diurnal pattern. (Mus musculus) PubMed

 4167.

OsCSLD1 function is required for hair elongation but not initiation. [CSLD1] (Mus musculus) PubMed

 4168.

The LONELY GUY (LOG) gene of rice is required to maintain meristem activity and its loss of function causes premature termination of the shoot meristem [LOG] (Mus musculus) PubMed

 4169.

Rice myosin gene controlled pollen development by sensing changed environmental factors.(Myosin XIB) (Mus musculus) PubMed

 4170.

The role of SSIIIa during starch synthesis in rice endosperm is reported.[SSIIIa] (Mus musculus) PubMed

 4171.

The results suggest that CDPK13, calreticulin and CRTintP1 might be important signaling components for response to cold stress in rice.[CDPK13, CRTintP1 proteins] (Mus musculus) PubMed

 4172.

Upregulation of MUS81 in response to DNA radiation damage is reported.[MUS81] (Mus musculus) PubMed

 4173.

The OsLPLA gene, which encoded 270 amino acids, was located on an approximately 21 Mb of chromosome 8 on the physical map of Oryza sativa Japonica type. OsLPLA transcripts were abundantly expressed in leaves and developing seeds.[LPLA] (Mus musculus) PubMed

 4174.

The results suggest that OsSNAP32 belongs to a novel member of this gene family encoding SNAP25-type proteins, involved in the rice responses to biotic and abiotic stresses.[OsSNAp32] (Mus musculus) PubMed

 4175.

purification and characterization of ACR2.1 and ACR2.2; ACR2.1 and, to a lesser extent, ACR2.2 exhibit bifunctional activities as phosphatases and arsenate reductases [ACR2.1, ACR2.2] (Mus musculus) PubMed

 4176.

These results demonstrate that rice Ugp1 is required for callose deposition during pollen mother cells meiosis and bridges the apoplastic unloading pathway and pollen development.[Ugp1] (Mus musculus) PubMed

 4177.

A phosphate starvation-induced acid phosphatase cDNA was cloned from the rice, Oryza sativa. The cDNA encoding O. sativa acid phosphatase (OsACP1) has 1100 bp with an open reading frame of 274 amino acid residues. (Mus musculus) PubMed

 4178.

NYC1 plays essential roles in the regulation of light-harvesting complex II and thylakoid membrane degradation during rice senescence.[ (Mus musculus) PubMed

 4179.

enhancing the Fe3+ chelate-reductase activity of rice plants that normally have low endogenous levels confers resistance to Fe deficiency[ferric citrate iron reductase] (Mus musculus) PubMed

 4180.

data together suggest that SRT1 is required for safeguard against genome instability and cell damage to ensure plant cell growth [SRT1] (Mus musculus) PubMed

 4181.

LA1 plays a negative role in polar auxin transport (PAT). Loss-of-function of LA1 enhances PAT greatly & alters endogenous IAA distribution in shoots, leading to reduced gravitropism, & therefore tiller-spreading phenotype of rice plants[LA1] (Mus musculus) PubMed

 4182.

In senescing leaves, Sgr regulates chlorophyll (Chl) degradation by inducing light-harvesting chlorophyll binding protein(LHCPII) disassembly through direct interaction.[Sgr] (Mus musculus) PubMed

 4183.

The results suggest that OsBISERK1 may be involved in disease resistance responses in rice.[OsBISERK1] (Mus musculus) PubMed

 4184.

We present a detailed characterization of the chitin oligosaccharide elicitor-induced transcriptional activator gene. It plays important roles in elicitor-induced defense signaling pathways in rice.[OsWRKY53] (Mus musculus) PubMed

 4185.

ygl1 locus was mapped to chromosome 5 and isolated by map-based cloning; sequence analysis revealed that it encodes the chlorophyll synthase [Ygl1] (Mus musculus) PubMed

 4186.

The OsGluRS gene (TIGR locus Os02 g02860) which encode glutamyl-tRNA synthetase was identified as the Cde1(t) gene.[Cde1(t)] (Mus musculus) PubMed

 4187.

RZF71 may play an important role in rice responses to salt and osmotic stresses as a transcription factor.[RZF71] (Mus musculus) PubMed

 4188.

over-expression of COIN enhanced tolerance to cold, salt and drought and increased cellular proline level [COIN] (Mus musculus) PubMed

 4189.

IRO2 regulates 59 Fe-deficiency-induced genes in roots [Iro2] (Mus musculus) PubMed

 4190.

OsDMC1 is essential for rice meiosis and plays an important role in homologous pairing[OsDMC1 ] (Mus musculus) PubMed

 4191.

The C-terminal extension of OsGAD2 plays a role as a strong autoinhibitory domain, and truncation of this domain causes the enzyme to act constitutively, with higher activity both in vitro and in vivo. (Mus musculus) PubMed

 4192.

UGE-1 over-expressed in A. thaliana conferred tolerance to salt, drought and freezing stress, and increased raffinose metabolism without altering plant morphology.[UGE-1] (Mus musculus) PubMed

 4193.

Identification of Pi39(t), gene conferring the broad-spectrum resistance to Magnaporthe oryzae.[Pi399(t)] (Mus musculus) PubMed

 4194.

These results suggest that RTBP1 plays dual roles in rice (Oryza sativa), as both a negative regulator of telomere length and one of positive and functional components for proper architecture of telomeres.[RTBP-1] (Mus musculus) PubMed

 4195.

In 3 elite rice varieties, the resistance conferring allele of the rice blast resistance gene Pi33 was introgressed from the wild rice Oryza rufipogon. (Mus musculus) PubMed

 4196.

results showed that constitutive expression of FCA RNA recognition motifs (RRMs) could regulate cellular size [FCA] (Mus musculus) PubMed

 4197.

A role for WRKY45 in Benzothiadiazole-induced and salicylic acid-mediated defense signaling in rice, is proposed. [WRKY45] (Mus musculus) PubMed

 4198.

results indicate that the product of DSH1 may be involved in plant viability or reproductive processes, and that the phenotype of sterility is apparently caused by loss of function of DSH1 in the stigma [DSH1] (Mus musculus) PubMed

 4199.

Study describes the low silicon rice 2 (Lsi2) gene, which is constitutively expressed in the roots; the protein is localized, on the plasma membrane of cells in both the exodermis and the endodermis and is a silicon efflux transporter.[Lsi2 protein] (Mus musculus) PubMed

 4200.

Cconstitutive expression of OsZIP4 changes the Zn distribution within rice plants and is a critical Zn transporter. (Mus musculus) PubMed

 4201.

The gibberellin-dependent GID1-SLR1 interaction also occurs in planta.[GID1, SLR1] (Mus musculus) PubMed

 4202.

D10 transcription has a role in the regulation of the branching inhibitor pathway. (Mus musculus) PubMed

 4203.

APO1 positively regulates class-C floral homeotic genes, but not class-B genes. (Mus musculus) PubMed

 4204.

The expressed OsGSTF5 is a phi class glutathione S-transferase and appears to play a role in the conjugation of herbicide.[OsGSTF5] (Mus musculus) PubMed

 4205.

HSF13 was a class C heat shock factor with all the conserved sequence elements of heat stress transcription factor. [HSF13] (Mus musculus) PubMed

 4206.

These results indicate that the germ cell-specific rice MEL1 gene regulates the cell division of premeiotic germ cells, the proper modification of meiotic chromosomes, and the faithful progression of meiosis.[MEL1] (Mus musculus) PubMed

 4207.

These results demonstrate that Os BOR1 is required both for efficient boron uptake and for xylem loading of boron. [BOR1] (Mus musculus) PubMed

 4208.

demonstrate a conserved function of OsBZR1 and an important role of 14-3-3 proteins in brassinosteroid signal transduction in rice[BZR1] (Mus musculus) PubMed

 4209.

Molecular cloning and functional analysis of Stay Green Rice (SGR) in O. sativa is reported.[SGR] (Mus musculus) PubMed

 4210.

findings show that a novel gene, VIRESCENT 2 (V2), encodes a new type of guanylate kinase GK (designated pt/mtGK) that is localized in plastids and mitochondria [viescent2] (Mus musculus) PubMed

 4211.

the residues forming the hydrophobic cavity play various important roles in the structure and function of rice nsLTP2, nonspecific lipid transfer protein 2 . (Mus musculus) PubMed

 4212.

This study analysed the rice pdc gene family and alterations in the efficacy of the ethanolic fermentation process, by production of transgenic plants over- and under-expressing Ospdc1 as well as over-expressing alcohol dehydrogenase proteins.[Ospdc1] (Mus musculus) PubMed

 4213.

We identified a cleistogamous mutant harbouring a missense mutation (I45T) in the class-B MADS-box gene SUPERWOMAN1 (SPW1), which specifies the identities of lodicules (equivalent to petals) and stamens. [Spw1] (Mus musculus) PubMed

 4214.

These studies demonstrated that SnRK1A is an important intermediate in the sugar signaling cascade.[SmRK1A] (Mus musculus) PubMed

 4215.

The responses to temperature of transgenic rice plants with 130 and 35% of the wild-type (WT) Rubisco content by transformation with rbcS cDNA in sense and antisense orientations, respectively.[rbcS] (Mus musculus) PubMed

 4216.

This article is the first report on the functional characterization of HMA9, a P(1B)-type metal efflux transporter, in O. sativa.[HMA9] (Mus musculus) PubMed

 4217.

OsNAC2 regulates shoot branching in rice. (Mus musculus) PubMed

 4218.

Repression of the rice RAR1 gene suppressed defense responses induced in the pti1a mutant, indicating that Pti1a negatively regulates RAR1-dependent defense responses.[Pti1a, RAR1] (Mus musculus) PubMed

 4219.

A gene encoding a Myb-like domain transcription factor with homology to Arabidopsis KANADI is the most probable candidate for RL10(t) (RL10(t). (Mus musculus) PubMed

 4220.

These results reveal a critical role of Os DCL4-mediated trans-acting-siRNA biogenesis in rice development.[DCL4] (Mus musculus) PubMed

 4221.

Overexpression of OsLFL1 might delay the flowering of W378 by repressing the expression of Ehd1.[OsLFL1] (Mus musculus) PubMed

 4222.

14-3-3 protein may play an important role in regulating ACS activity.(ASC) (Mus musculus) PubMed

 4223.

OPR7 encodes the enzyme catalysing the reduction of natural (+)-cis-12-oxophytodienoate for jasmonic acid biosynthesis [OPR7] (Mus musculus) PubMed

 4224.

cloning of ROMT-15 and ROMT-17; ROMT-15 and -17 are cation-dependent and mutation of the predicted metal binding sites resulted in the loss of the enzyme activity. [ROMT-17] (Mus musculus) PubMed

 4225.

not only required for arbuscular mycorrhizal symbiosis in rice but also is able to complement a Medicago truncatula dmi3 mutant [Dmi3] (Mus musculus) PubMed

 4226.

This study identified cis-acting elements and their binding proteins of rice WRKY13, a gene that plays a pivotal role in disease resistance against bacterial and fungal pathogens.[WRKY13] (Mus musculus) PubMed

 4227.

OsPI8-1 has multiple endogenous roles on developmental regulation.[OsPI8-1] (Mus musculus) PubMed

 4228.

IDEF1 overexpression leads to enhanced expression of the iron deficiency-induced transcription factor gene OsIRO2, suggesting the presence of a sequential gene regulatory network [IDEF1] (Mus musculus) PubMed

 4229.

Numerous truncated transcripts of OsVP1 resulting from an unusual post-transcriptional processing, were detected in four rice cultivars; various proportions of the transcripts were associated with preharvest sprouting. (Mus musculus) PubMed

 4230.

These results also suggest that OsWRKY31 might be a common component in the signal transduction pathways of the auxin response and the defense response in rice.[OsWRKY31] (Mus musculus) PubMed

 4231.

study revealed that the JIOsPR10 protein was expressed in developmental tissues, including in flower and root; the protein was also expressed under abiotic stresses, such as occurs during senescence and wounding[JIOsPR10] (Mus musculus) PubMed

 4232.

CutA1 proteins from Thermus thermophilus (TtCutA1) and Oryza sativa (OsCutA1) and Pyrococcus horikoshii (PhCutA1)were examined, in order to elucidate the stabilization mechanism of PhCutA1.[CutA1] (Mus musculus) PubMed

 4233.

Results suggest that cytosolic Ca2+ concentration may modulate NADPH oxidase activity by regulating the interaction between Rac GTPase and Rboh: [NADPH oxidase] (Mus musculus) PubMed

 4234.

Results indicate that Rac1, RAR1, HSP90, and HSP70 form one or more protein complexes in rice cells and suggest that these proteins play important roles in innate immunity in rice: [RAR1] (Mus musculus) PubMed

 4235.

dh1 presented severer mutation phenotype under relatively longer daylight than under shorter daylight implied that shorter daylight induced the expression of gene(s) redundant to DH1 in function and partially compensated for the loss-of-function[DH1] (Mus musculus) PubMed

 4236.

The functional roles of two close homologs, MADS22 and MADS55, in the control of meristem identity and flowering time are reported.[MADS22; MADS55] (Mus musculus) PubMed

 4237.

UDP-glucose pyrophosphorylase 1 (UGPase1) plays a key role in pollen development as well as seed carbohydrate metabolism.[UGPase1] (Mus musculus) PubMed

 4238.

rice OSBZ8 is the prime factor interacting with both typical ABRE(s) and ABRE-like sequences (OSBZ8). (Mus musculus) PubMed

 4239.

Rice GH3-8, an auxin-responsive gene functioning in auxin-dependent development, activates disease resistance in a salicylic acid signaling- and jasmonic acid signaling-independent pathway.[GH3-8, expansin] (Mus musculus) PubMed

 4240.

Transgenic rice plants were tolerant to salt and drought during anthesis stage without any yield penalty as compared to unstressed transgenic plants[OsiSAP8] (Mus musculus) PubMed

 4241.

These results indicate that Hd3a and RFT1 act as floral activators under short-day conditions, and that RFT1 expression is partly regulated by chromatin modification.[Hd3a, RFT1] (Mus musculus) PubMed

 4242.

OsEXO1 interacted with rice DNA polymerase lambda (OsPol lambda), the 70 kDa subunit b of rice replication protein A (OsRPA70b), and the 32 kDa subunit 1 of rice replication protein A (OsRPA32-1). [EXO1; RPA70b; RPA32-1; Pol lamba] (Mus musculus) PubMed

 4243.

Results suggest that OsABI5 could regulate the adaptive stress response and plant fertility [OsABI5] (Mus musculus) PubMed

 4244.

XRCC1 contributes to DNA repair pathways that differ from the mammalian Bbase escision repair system. [XRCC1] (Mus musculus) PubMed

 4245.

Data show that rice contains two TPD1-like genes, OsTDL1A and OsTDL1B. Both are co-expressed with MSP1 in anthers during meiosis: [OsTDL1A, OsTDL1B and MSP1] (Mus musculus) PubMed

 4246.

Results collectively suggest that OsRar1 and OsSGT1 might be differentially required for rice basal disease resistance (OsRar1 and OsSGT1). (Mus musculus) PubMed

 4247.

The role of JASMONATE RESISTANT 1 (JAR1) in phytochrome metabolism and jasmonic acid signaling is reported.[JAR1] (Mus musculus) PubMed

 4248.

Alternative splicing takes place in both OsMET1 genes and appears to be regulated in a tissue-specific manner.[OsMET1a, OsMET1b] (Mus musculus) PubMed

 4249.

Subcellular localization of OsACR9 and its accumulation and cellular distribution in various rice organs were examined by transient expression analysis and immunological methods using a monospecific antibody, respectively.[Acr9] (Mus musculus) PubMed

 4250.

OsNuc37, a glycoprotein localized in the nucleus, is the executor for DNA laddering.[OsNuc37] (Mus musculus) PubMed

 4251.

IDEF2 bound to OsYSL2 promoter region containing the binding core site, suggesting direct regulation of OsYSL2 expression[ iron deficiency-responsive element 2 ] (Mus musculus) PubMed

 4252.

This result indicates that DCW11 could play a role as a mitochondrial signal transduction mediator in pollen germination.[DCW11] (Mus musculus) PubMed

 4253.

The 5' UTR intron of the rubi3 gene elevated gene expression of the GUS reporter gene mainly at mRNA accumulation level, but also stimulated enhancement at translational level (rubi3). (Mus musculus) PubMed

 4254.

Overexpression of ZFP252 in rice increased the amount of free proline and soluble sugars, elevated the expression of stress defense genes and enhanced rice tolerance to salt and drought stresses (ZFP252). (Mus musculus) PubMed

 4255.

Biosynthesis genes for jasmonate, ethylene, and reactive oxygen species, as well as putative downstream targets involved in the stress-related process, were up-regulated in OsMADS26-overexpressing plants. [MADS26] (Mus musculus) PubMed

 4256.

The male sterility is controlled by a single recessive gene of add(t) which is mapped between the markers of R02004 (InDel) and RM300 (SSR) on chromosome 2.[add(t)] (Mus musculus) PubMed

 4257.

VR1 is a new male fertility controlling gene located on chromosome 4 in rice (VR1). (Mus musculus) PubMed

 4258.

OsMADS2 and OsMADS4 show unequal redundancy of class B function.[OsMADS2, OsMADS4] (Mus musculus) PubMed

 4259.

OsTudor-SN is a component of the RNA transport particle, and may control storage protein biosynthesis by regulating one or more processes leading to the transport, localization and anchoring of their RNAs to the cortical ER. (Mus musculus) PubMed

 4260.

The functional expression and characterization of Flavanone 3beta-hydroxylases from rice is reported.[F3H] (Mus musculus) PubMed

 4261.

OsITL1 inversely regulates plant responses to osmotic stress.[OsITL1] (Mus musculus) PubMed

 4262.

Data suggest that eIF-1 has a central function in salt-stress adaptation in rice by regulating ion accumulation and the intracellular redox status.[Os07g34589] (Mus musculus) PubMed

 4263.

The function of granule-bound starch synthase I (GBSSI) in rice, including the synthesis of extra-long unit chains of amylopectin, is reported.[GBSSI] (Mus musculus) PubMed

 4264.

The ORF79 protein is expressed from a dicistronic gene atp6-orf79 in rice [ORF79] (Mus musculus) PubMed

 4265.

The function of the sucrose nonfermenting 1-related protein kinase2 (SnRK2) SAPK4 in the salt stress response of rice, is characterized.[SAPK4] (Mus musculus) PubMed

 4266.

The docking model can well interpret the specificity of protein Pir7b towards the anilid moiety of the substrates and provide valuable structure information about the ligand binding to protein Pir7b.[Pir7b] (Mus musculus) PubMed

 4267.

OsDREB1F gene encodes a transcription activator, and can specifically bind to DRE/CRT element(G/ACCGAC) but not to ABRE element (OsDREB1F). (Mus musculus) PubMed

 4268.

OsTRBF1, OsTRBF2 and OsTRBF3 play combinatory roles in the function and structure of telomeres in rice. (OsTRBF1)(OsTRBF2)(OsTRBF3) (Mus musculus) PubMed

 4269.

These results reinforced the possibility that OsXIP is involved in plant defense mechanisms against phytopathogens.[OsXIP] (Mus musculus) PubMed

 4270.

Results indicate that Lsi6 is a transporter responsible for the transport of Si out of the xylem and subsequently affects the distribution of Si in the leaf: [Lsi6] (Mus musculus) PubMed

 4271.

Three ATG triplets in the polylinker decreased the synthesis of the HKT1 transporter and that the lower amount of transporter caused the functional change.[HKT1] (Mus musculus) PubMed

 4272.

Nodulin26-like Intrinsic Proteins (NIPs) OsNIP2;1 and OsNIP3;2 from Oryza sativa, and LjNIP5;1 and LjNIP6;1 from Lotus japonicus are bi-directional As(III) channels [Nodulin26-like Intrinsic Proteins (NIPs) OsNIP2;1 and OsNIP3;2] (Mus musculus) PubMed

 4273.

Rice ceramidase uses ceramide instead of phytoceramide as a substrate, and is localized to the endoplasmic reticulum and Golgi. [Os01g43520] (Mus musculus) PubMed

 4274.

Nal1 affects polar auxin transport as well as the vascular patterns of rice plants and plays an important role in the control of lateral leaf growth. (Mus musculus) PubMed

 4275.

The results suggest that OsDRF1 plays a role in disease resistance via upregulating defense-related gene expression. [OsDRF1] (Mus musculus) PubMed

 4276.

Wax Crystal-Sparse Leaf1 encodes a beta-ketoacyl CoA synthase involved in biosynthesis of cuticular waxes on rice leaf[WSL1] (Mus musculus) PubMed

 4277.

The strand-exchange activity of the Oryza sativa DMC1A protein was much higher than that of the DMC1B protein (DMC1A and DMC1B). (Mus musculus) PubMed

 4278.

Data show that Spl11 mutants have delayed flowering under long-day conditions and that SPL11 negatively regulates Spin1 transcript levelspossibly via ubiquitination: [SPIN1] (Mus musculus) PubMed

 4279.

The identification and characterization of a DROOPING LEAF (DL) mutation in the descendants of a mutable line, IM294, are reported. (Mus musculus) PubMed

 4280.

The expression pattern of SHOOT ORGANIZATION2 in developing rice leaves is reported.[SHO2] (Mus musculus) PubMed

 4281.

Study reports the cloning of a newly identified QTL, qSW5 (QTL for seed width on chromosome 5), involved in the determination of grain width in rice.[qSW5] (Mus musculus) PubMed

 4282.

These results suggest that there may be a conserved function between OsFVE and FVE in the control of flowering time.[OsFVE] (Mus musculus) PubMed

 4283.

Results strongly suggest that Pho1 plays a crucial role in starch biosynthesis in rice endosperm at low temperatures and that one or more other factors can complement the function of Pho1 at high temperatures: [Pho1] (Mus musculus) PubMed

 4284.

The expression pattern of the rubi3 promoter as well as the effects of the rubi3 5'-UTR (5' untranslated region) intron and the 5' terminal 27 bp of the rubi3 coding sequence on the activity of the promoter in transgenic rice plants, was analyzed.[Rubi3] (Mus musculus) PubMed

 4285.

Thehe rice CYP85A1 (OsCYP85A1) enzyme functions as a CS synthase rather than both CS synthase and BL synthase were examined. (OsCYP85A1) (Mus musculus) PubMed

 4286.

Transcripts of sucrose transporter OsSUT2M were higher in source leaf blades than in other organs at the same development stage, whereas transcripts of sucrose transporter OsSUT5Z were less traceable in all organs investigated [OsSUT2M and OsSUT5Z] (Mus musculus) PubMed

 4287.

These results suggest that the diacylglycerol kinase OsBIDK1 may play a role in disease resistance responses [BIDK1]. (Mus musculus) PubMed

 4288.

These results suggest that the OsMADS1 intragenic sequence, largely intron 1, contains a key regulatory region(s) essential for expression.[OsMADS1] (Mus musculus) PubMed

 4289.

This is the first report on in vitro characterization of Rad51 protein from crop plants.[OsRAD51] (Mus musculus) PubMed

 4290.

Degradation of ROOT ARCHITECTURE ASSOCIATED1 is essential for the onset of anaphase in the cell cycle during root development. [OsRAA1] (Mus musculus) PubMed

 4291.

Complementary DNA clones of both BAD1 and BAD2 were isolated and expressed in E. coli. [BAD1, BAD2] (Mus musculus) PubMed

 4292.

These data indicate that the three cell-wall invertase genes play complementary/synergetic roles in assimilate unloading during the grain filling stage.[OsCIN1, OsCIN2, OsCIN3] (Mus musculus) PubMed

 4293.

To study the effects of growing rice leaves under the treatment of elevated CO(2), changes in photosynthesis, photosynthate accumulation, sucrose phosphate synthase and sucrose synthase and their gene expressions were measured.[SPS, SS]] (Mus musculus) PubMed

 4294.

PDF1B mutants have severe defects in chloroplasts and mild defects in mitochondria. Gene expression in both organelles was altered. [PDF1B] (Mus musculus) PubMed

 4295.

Results suggest that RACK1A functions in rice innate immunity by interacting with multiple proteins in the Rac1 immune complex: [RACK1A] (Mus musculus) PubMed

 4296.

Thioredoxin m plays an important role in the redox regulation of chloroplast target proteins. Mutation of this gene inhibits growth and chloroplast development. [Ostrxm] (Mus musculus) PubMed

 4297.

Rice Indeterminate 1 (RID1) gene acts as the master switch for the transition from the vegetative to reproductive phase.[RID1] (Mus musculus) PubMed

 4298.

Os03g52760 is a myo-inositol kinase. Mutation leads to reductions in seed phytic acid. [OsMIK] (Mus musculus) PubMed

 4299.

Crossing alloplasmic cytoplasmic male sterility lines of rices with wild-type rice harboring the mitochondrial orfH79 gene restores fertility. [orfH79] (Mus musculus) PubMed

 4300.

rice JMJ706 encodes a heterochromatin-associated H3K9 demethylase involved in the regulation of flower development in rice[JMJ706] (Mus musculus) PubMed

 4301.

NOL and NYC1 are co-localized in the thylakoid membrane and act in the form of a complex as a chlorophyll b reductase. [NOL; NYC1] (Mus musculus) PubMed

 4302.

The recessive gene xa24 confers disease resistance to Xanthomonas oryzae at the seedling and adult stages. [xa24] (Mus musculus) PubMed

 4303.

Co-expression patterns of sense and antisense OsDof12 transcipts might be attributed to the basically common nature of the two promoters (OsDof12). (Mus musculus) PubMed

 4304.

OsCIPK23 is a multistress induced gene and likely mediates a signaling pathway commonly shared by both pollination and drought stress responses in rice.[CIPK23] (Mus musculus) PubMed

 4305.

Pit is a rice blast resistance gene that is activated by insertion of a retrotransposon in the Pit promoter region. [Pit] (Mus musculus) PubMed

 4306.

rpms1 and rpms2 interact in controlling male sterility. [rpms1; rpms2] (Mus musculus) PubMed

 4307.

OscFBP1 is a cytosolic fructose-1,6-bisphosphatase plays a major role in the cytosolic conversion of triose-phosphates to sucrose and regulation of carbohydrate partitioning. [OscFBP1] (Mus musculus) PubMed

 4308.

These results demonstrate that Xb15 encodes a protein phosphatase 2C that negatively regulates the XA21-mediated innate immune response [XB15]. (Mus musculus) PubMed

 4309.

The altered expression levels of OsBADH2 gene influence aroma accumulation, and the prevalent aromatic allele probably has a single evolutionary origin.[OsBADH2] (Mus musculus) PubMed

 4310.

Rice OsCASTOR can fully complement symbiosis defects in the corresponding Lotus mutant lines for both mycorrhizal and rhizobial symbiosis. [OsCASTOR] (Mus musculus) PubMed

 4311.

Abscisic acid does not inhibit the interaction between the rice genes FCA and FY. [OsFca; OsFY] (Mus musculus) PubMed

 4312.

OsbZIP23 has a major role in ABA-dependent drought and salinity tolerance and has high potential usefulness in genetic improvement of stress tolerance. (Mus musculus) PubMed

 4313.

BC10 is a DUF266-containing Golgi-localized glycosyltransferase that is required for cell wall biosynthesis. [BC10] (Mus musculus) PubMed

 4314.

Pikm-specific resistance is conferred by cooperation of Pikm1-TS and Pikm2-TS. (Mus musculus) PubMed

 4315.

OsHsp90 functioned as a chaperone, binding to a subset of substrates, and maintained E. coli growth well at high temperatures. [Hsp90] (Mus musculus) PubMed

 4316.

RETARDED PALEA1 is only expressed in palea primordium during early flower development. Ectopic expression of REP1 caused the asymmetrical overdifferentiation of the palea cells, altering their floral asymmetry. [REP1] (Mus musculus) PubMed

 4317.

Os-CASTOR and Os-POLLUX are indispensable for mycorrhizal symbiosis in rice. Os-POLLUX can restore nodulation, but not rhizobial infection, to a Medicago truncatula dmi1 mutant. [CASTOR; POLLUX] (Mus musculus) PubMed

 4318.

OsPht1;2 and OsPht1;6 are abundantly expressed under Pi starvation in rice. OsPT6 plays a broad role in Pi uptake, whereas OsPT2 is a low-affinity Pi transporter. [OsPht1;2 and OsPht1;6] (Mus musculus) PubMed

 4319.

RIM1 functions as a host factor that is required for multiplication of Rice dwarf virus in rice. [RIM1] (Mus musculus) PubMed

 4320.

EXTRA GLUME1 regulates rice empty-glume fate and spikelet development. EG1 is expressed strongly in inflorescence primordia and weakly in developing floral primordia. [EG1] (Mus musculus) PubMed

 4321.

OsGSR1 is a positive regulator of the gbberellin response, and regulates brassinosteroid biosynthesis. [OsGSR1] (Mus musculus) PubMed

 4322.

OsFLS2 is the rice ortholog of AtFLS2. It recognizes the flg22 peptide of flagellin. Overexpression enhances immune responses involving cell death but does not affect resistance to Acidovorax. [OsFLS2] (Mus musculus) PubMed

 4323.

OsPIP2;7 is involved in rapid water transport and maintenance of the water balance in cells, and improves the tolerance of rice to low temperature stress. [OsPIP2;7] (Mus musculus) PubMed

 4324.

starch branching enzyme I was characterized with respect to biochemical and crystallographic properties. [BEI] (Mus musculus) PubMed

 4325.

OsSPX1 is induced specifically by phosphorus starvation in roots. [OsSPX1] (Mus musculus) PubMed

 4326.

OsCDT1 functions to prevent entry of cadmium into yeast and plant cells and thereby enhance their Cd tolerance. [OsCDT1] (Mus musculus) PubMed

 4327.

crystal structure of Oryza sativa GID1 (OsGID1) bound with GA(4) and GA(3) at 1.9 A resolution [GID1] (Mus musculus) PubMed

 4328.

OsA8 not only influences the uptake of Phosphorus (P) by roots, but also the translocation of P from the roots to the shoots in rice.[OsA8] (Mus musculus) PubMed

 4329.

OsbZIP72 plays a positive role in drought resistance through ABA signaling. (Mus musculus) PubMed

 4330.

direct evidence that OsKO2 is involved in the sequential oxidation of ent-kaurene to ent-kaurenoic acid in gibberellin biosynthesis in rice [ent-kaurene oxidase 2] (Mus musculus) PubMed

 4331.

Gain-of-function tests in transgenic rice and Arabidopsis thaliana showed that constitutive expression of GAP1 (GTPase-activating protein 1)led to increased resistance to bacterial pathogens in both monocots and dicots.[GAP1] (Mus musculus) PubMed

 4332.

The defect of Os Phot1a affects degradation of chlorophylls and carotenoids, and under photosynthetically active photon fluxes, mutation of phot1a results in loss of photosynthetic capacity owing to the damage of photosystems.[Phot1a] (Mus musculus) PubMed

 4333.

Transgenic rice plants overexpressing OsPIP1;3 showed an enhanced level of chilling tolerance. [OsPIP1;3] (Mus musculus) PubMed

 4334.

These results indicate that OsGH3.1 overexpression reduces auxin content, inhibits cell growth and cell wall loosening, and enhances resistance to a fungal pathogen.[OsGH3.1] (Mus musculus) PubMed

 4335.

These results suggest that ONAC045 encodes a novel stress-responsive NAC transcription factor and is potential useful for engineering drought and salt tolerant rice.(NAC) (Mus musculus) PubMed

 4336.

Rcn1 is the first functionally defined plant ATP-binding cassette protein subfamily G protein gene that controls shoot branching and could thus be significant in future breeding for high-yielding rice.[Rcn1] (Mus musculus) PubMed

 4337.

study clarified the biochemical & structural features of the DNA binding domain of RTBP1; results suggest helix 3 functions as a sequence-specific recognition helix while the N-terminal arm stabilizes the DNA binding [RTBP1; telomere binding protein 1] (Mus musculus) PubMed

 4338.

The presence of two genes (Pi5-1, Pi5-2) is required for rice Pi5-mediated resistance to Magnaporthe oryzae.[Pi5-1; Pi5-2] (Mus musculus) PubMed

 4339.

study describes the identification of Pi41, a major gene which contributes to the blast resistance of cultivar 93-11 [Pi41] (Mus musculus) PubMed

 4340.

SP1 encodes a putative transporter of the peptide transporter family, which affects the panicle size of rice plants. [short panicle1] (Mus musculus) PubMed

 4341.

OsVPE1 is a cysteine protease that plays a crucial role in the maturation of rice glutelins. [OsVPE1] (Mus musculus) PubMed

 4342.

the expression of OsARGOS causes organ enlargement [ARGOS] (Mus musculus) PubMed

 4343.

OsCAS could not interact with serine-acetyltransferase, indicating that OsCAS mainly functions in cyanide detoxification.[OsCAS] (Mus musculus) PubMed

 4344.

In a jasmonate (JA)-deficient rice mutant, the photodestruction of phyA is delayed as shown by in vivo spectroscopy and Western blot analysis.[PhyA] (Mus musculus) PubMed

 4345.

Three PUL-deficient mutants were generated to investigate the function of PUL in starch biosynthesis.[Pullulanase] (Mus musculus) PubMed

 4346.

The OsHSF7 gene was found to be rapidly expressed in high levels in response to temperature, which indicates that it may be involved in heat stress reception and response.[OsHSF7] (Mus musculus) PubMed

 4347.

Data showed that OsDof12 had transcriptional activity and the expression of OsDof12 was not tissue-specific and fluctuated at different development stages: [OsDof12] (Mus musculus) PubMed

 4348.

OsWRKY24 is a novel type of transcriptional repressor that inhibits both gibberellin and abscisic acid signaling. [WRKY24] (Mus musculus) PubMed

 4349.

The OPB gene encodes a transcription factor with a zinc finger motif, and is involved in the regulation of genes related to cellular proliferation and floral organ identity. [OPB] (Mus musculus) PubMed

 4350.

Glucose suppressed the expression of ABA catabolism genes OsABA8ox3 and OsABA8ox2, which led to the delay of germination. [OsABA8ox2; OsABA8ox3] (Mus musculus) PubMed

 4351.

Accumulation of the Rdd1 transcript is circadian clock-regulated, and has effects on the regulation of plant growth, flowering and grain size. [Rdd1] (Mus musculus) PubMed

 4352.

OsATG10b plays an important role in the survival of rice cells against oxidative stresses.[OsATG10b] (Mus musculus) PubMed

 4353.

DLT leads to decreased brassinosteroid responses, and is involved in feedback inhibition of brassinosteroid biosynthesis genes. [DLT] (Mus musculus) PubMed

 4354.

OsNek3 is downstream of DCW11 in retrograde signaling from the mitochondria to the nucleus and is involved in cytoplasmic male sterility. [OsNek3] (Mus musculus) PubMed

 4355.

ONAC063 may play an important role in eliciting responses to high-salinity stress.[ONAC063] (Mus musculus) PubMed

 4356.

PLA3/GO encodes a glutamate carboxypeptidase II and is an ortholog of Arabidopsis AMP1 and maize VP8. [PLA3] (Mus musculus) PubMed

 4357.

The transcription factor OsNAC4 is a key positive regulator of plant hypersensitive cell death (Mus musculus) PubMed

 4358.

Metallothionein OsMT1a participates directly in ROS scavenging pathway and regulates expression of the zinc finger transcription factors via the alteration of Zn(2+) homeostasis, which leads to improved plant stress tolerance. [MT1a] (Mus musculus) PubMed

 4359.

Grat was located to a region of 42.4 kb flanked by two microsatellite markers RM2-97 and RM13553. [grat] (Mus musculus) PubMed

 4360.

STAR1 and STAR2 are expressed mainly in the roots, interact together to form a complex that functions as an ABC transporter, and are responsible for Al tolerance in rice. [2 genes, STAR1 and STAR2] (Mus musculus) PubMed

 4361.

Data show that the expression of the OsPUL gene was maintained at a significant level during the entire grain filling period and in the late stage of seed germination, which coincided with its involvement in starch anabolism and catabolism: [OsPUL] (Mus musculus) PubMed

 4362.

Results suggest that WOX11 may be an integrator of auxin and cytokinin signaling that feeds into RR2 to regulate cell proliferation during rice crown root development [WOX11]. (Mus musculus) PubMed

 4363.

The GLO-suppressed plants showed typical photorespiration-deficient phenotypes. [GLO] (Mus musculus) PubMed

 4364.

OsIAA1 may play important roles in the cross-talk of auxin and brassinosteroid signaling pathways and plant morphogenesis. [IAA1] (Mus musculus) PubMed

 4365.

OsMYB3R-2 regulates the progress of the cell cycle during chilling stress. (Mus musculus) PubMed

 4366.

OsDEG10 is a small RBP involved in the response to various abiotic stresses.(OsDEG10) (Mus musculus) PubMed

 4367.

OsPLDbeta1 functions as a negative regulator of defense responses and disease resistance in rice. (Mus musculus) PubMed

 4368.

[2 genes-virescent3 & stripe1] Virescent3 encodes the large subunit of the ribonucleotide reductase and is required for chloroplast biogenesis. Stripe1 encodes the small subunit of the ribonucleotide reductase and is required for chloroplast biogenesis. (Mus musculus) PubMed

 4369.

Results identify the role of SHALLOT-LIKE1 (SLL1) in the modulation of leaf abaxial cell development and in sustaining abaxial characteristics during leaf development [SLL1]. (Mus musculus) PubMed

 4370.

Race-specific pathogen-induced Xa13 expression is critical for infection. [Xa13] (Mus musculus) PubMed

 4371.

OsSKIPa has evolved a specific function in positive modulation of stress resistance through transcriptional regulation of diverse stress-related genes in rice[ski-interacting protein ] (Mus musculus) PubMed

 4372.

LAX1 protein is trafficked to the axillary meristem in a stage- and direction-specific manner. (Mus musculus) PubMed

 4373.

The structures of the rice KARI-Mg(2+) and rice KARI-Mg(2)(+)-NADPH complexes to 1.55 A and 2.80 A resolutions, respectively, were determined. [KARI] (Mus musculus) PubMed

 4374.

These results demonstrate roles for OsYSL15 in iron uptake and distribution in rice plants.[OsYSL15] (Mus musculus) PubMed

 4375.

Overexpression of OsBIPP2C2a in transgenic tobacco plants resulted in enhanced disease resistance and constitutive expression of defense-related genes. [OsBIPP2C2] (Mus musculus) PubMed

 4376.

The level of APO1 activity regulates the inflorescence form through control of cell proliferation in the meristem.[APO1] (Mus musculus) PubMed

 4377.

PAIR3 functions in gametophyte development, and is required for chromosome pairing but not cytokinesis. [PAIR3] (Mus musculus) PubMed

 4378.

Northern analysis showed that Isu1 was downregulated in iron-deficient rice root.[Isu1] (Mus musculus) PubMed

 4379.

Both ef1 or ef1-h alleles can be used as new gene sources in developing rice varieties with extremely long basic vegetative growth periods for low latitudes.[Ef1] (Mus musculus) PubMed

 4380.

study identified the erect-pose panicle (EP) candidate gene and elucidated its effects on several agronomic traits [EP] (Mus musculus) PubMed

 4381.

results demonstrate rice synthesizes C-glucosylated flavones through the concerted action of a CGT and dehydratase acting on activated 2-hydroxyflavanones, as an alternative means of generating flavonoid metabolites[OSCGT] (Mus musculus) PubMed

 4382.

Results show that expression of both plastidial methionine sulfoxide reductases, OsMSRA4.1 and OsMSRB1.1, are constitutively expressed in all organs and can be induced by various stress conditions: [OsMSRA4.1 and OsMSRB1.1] (Mus musculus) PubMed

 4383.

ETR2 delays flowering and causes starch accumulation in stems by regulating downstream genes. (Mus musculus) PubMed

 4384.

The AP37 gene has the potential to improve drought tolerance in rice without causing undesirable growth phenotypes. (Mus musculus) PubMed

 4385.

SL1 positively regulates SPW1/OsMADs16, and is expressed at early flower developmental stages. [SL1] (Mus musculus) PubMed

 4386.

NYC3 encodes a plastid-localizing alpha/beta hydrolase-fold family protein with an esterase/lipase motif, but does not show chlorophyll hydrolase activity. [NYC3] (Mus musculus) PubMed

 4387.

OGR1 encodes a PPR protein of the DYW sub-group localized to mitochondria and is essential for mitochondrial RNA editing. [OGR1] (Mus musculus) PubMed

 4388.

Transcriptional regulation of GAMYB has a role in anther development in rice. (Mus musculus) PubMed

 4389.

Suppression of the 1d-myo-inositol 3-phosphate synthase gene, RINO1, varies within caryopses, which results in differences in phytic acid accumulation in transgenic seeds. [RINO1] (Mus musculus) PubMed

 4390.

MER3 is required for normal meiotic crossover formation, but not for presynaptic alignment in rice. (Mus musculus) PubMed

 4391.

DWARF27 (D27) is involved in the MAX/RMS/D pathway, in which D27 acts as a new member participating in the biosynthesis of strigolactones. (Mus musculus) PubMed

 4392.

RISBZ1 and RPBF regulate seed storage protein gene expression, and positively regulate the aleurone layer number-related genes. [RISBF1; RPBF] (Mus musculus) PubMed

 4393.

The expression patterns and functional properties of three rice HKT transporters, OsHKT1;1, OsHKT1;3, and OsHKT2;1, is reported.[OsHKT1, OsHKT2] (Mus musculus) PubMed

 4394.

A newly detected mutant gene named ef7 confers an extremely long basic vegetative growth phase and increases photoperiod sensitivity.[ef7] (Mus musculus) PubMed

 4395.

OsSSI2 is involved in the negative regulation of defense responses in rice. (Mus musculus) PubMed

 4396.

Post-translational processing of glutelin is not necessary for trafficking and stable accumulation. [GluA2] (Mus musculus) PubMed

 4397.

OsWRKY13-mediated signalling pathways are partitioned by different transcription factors. [WRKY13] (Mus musculus) PubMed

 4398.

A spontaneous rice mutant, Epi-d1 showing a metastable dwarf phenotype, was identified.[DWARF1] (Mus musculus) PubMed

 4399.

D14 encodes a protein of the alpha/beta-fold hydrolase superfamily, and functions downstream of strigolactone synthesis, as a component of hormone signaling. [D14] (Mus musculus) PubMed

 4400.

Lsi1 mediates the uptake of undissociated methylated As in rice roots.[Lsi1] (Mus musculus) PubMed

 4401.

The results uncover a new mechanism for light-regulated plant growth, namely, light not only inhibits cell elongation but also suppresses cell division through HAL3 and E3 ubiquitin ligase. [HAL3] (Mus musculus) PubMed

 4402.

Results suggest that quantitative effect of light on flowering in night break is mediated by the regulation of Hd3a transcription by phyB: [phyB] (Mus musculus) PubMed

 4403.

OsMADS50 and OsMADS56 function antagonistically in regulating long day-dependent flowering by controlling expression of OsLFL1 and Ehd1. [MADS50] (Mus musculus) PubMed

 4404.

OsFCA protein interacts with a host of proteins including components involved in RNA processing. [OsFCA] (Mus musculus) PubMed

 4405.

OsKCH1 is associated with cortical microtubules and actin microfilaments. [OsKCH1] (Mus musculus) PubMed

 4406.

OsSPX1 may be a regulator involved in the transcriptions of OsSPX2, 3 and 5.[OsSPX1, OsSPX3] (Mus musculus) PubMed

 4407.

HTD2 gene could negatively regulate tiller bud outgrowth by the strigolactone pathway.[HTD2] (Mus musculus) PubMed

 4408.

D88, Dwarf88, represents a new category of genes that regulates cell growth and organ development and consequently plant: [D88] architecture. (Mus musculus) PubMed

 4409.

OsBWMK1 may mediate salicylic acid-dependent defense responses by activating the OsWRKY33 transcription factor in plants. (OsBWMK1) (OsWRKY33) (Mus musculus) PubMed

 4410.

Data show that over-expression of OsTIFY11a, one of the stress-inducible genes, resulted in significantly increased tolerance to salt and dehydration stresses: [OsTIFY11a] (Mus musculus) PubMed

 4411.

Results indicate that OsTGAP1 functions as a key regulator of the coordinated transcription of genes involved in inductive diterpenoid phytoalexin production:[OsTGAP1] (Mus musculus) PubMed

 4412.

A novel BR-induced rice gene BRASSINOSTEROID UPREGULATED1 (BU1), encoding a helix-loop-helix protein, is described.[BU1] (Mus musculus) PubMed

 4413.

We identified three tandem W-box elements, putative recognition sites for WRKY transcription factors, as cis elements that are essential to the elicitor-responsiveness of OsWRKY53.[OsWRKY53] (Mus musculus) PubMed

 4414.

ADL1 encodes a plant-specific calpain-like cysteine proteinase orthologous to maize. It plays an important role in pattern formation of the leaf and embryo by promoting proper epidermal development. ADL1 (Mus musculus) PubMed

 4415.

Data show that a major and cold-induced thioredoxin h of rice, OsTrx23, has an inhibitory activity on stress-activated mitogen-activated protein kinases (MAPKs), OsMPK3 and OsMPK6 in vitro [mpk3, mpk6] (Mus musculus) PubMed

 4416.

The s73 mutant displays early flowering and photoperiodic insensitivity due to a null mutation in the PHOTOPERIOD SENSITIVITY5 (SE5) gene, which encodes an enzyme implicated in phytochrome chromophore biosynthesis.[SE5] (Mus musculus) PubMed

 4417.

TDD1 encodes an anthranilate synthase beta-subunit. Mutant plants exhibit decreased levels of Trp and indole acetic acid. [TDD1] (Mus musculus) PubMed

 4418.

OsEF3 regulates heading date by influencing the basic vegetative growth stage and does not affect photoperiodic sensitivity. [EF3] (Mus musculus) PubMed

 4419.

show the molecular mechanism of deepwater response through the identification of the genes SNORKEL1 and SNORKEL2, which trigger deepwater response by encoding ethylene response factors involved in ethylene signalling [SK1 & SK2] (Mus musculus) PubMed

 4420.

OsNAC5 is a novel senescence-associated abscissic acid-dependent NAC transcription factor and its function could be related to Fe, Zn and amino acids remobilization from green tissues to seeds.[OsNAC5] (Mus musculus) PubMed

 4421.

Both OsWRKY45-1- and OsWRKY45-2 are positive regulators in rice resistance against M. grisea, but the former is a negative regulator and the latter is a positive regulator in rice resistance against Xanthomonas.[OsWRKY45-1- and OsWRKY45-2] (Mus musculus) PubMed

 4422.

SAUR39 acts as a negative regulator for auxin synthesis and transport.[SAUR39] (Mus musculus) PubMed

 4423.

The morphology of the three phytochrome genes (PHYA, PHYB and PHYC) triple mutant seedlings grown under red or far-red light appears completely the same as etiolated seedlings, and they show no expression of the light-induced genes: [PHYA, PHYB, PHYC] (Mus musculus) PubMed

 4424.

The over-expression of OsDREB1D conferred cold and high-salt tolerance in transgenic plants.[OsDREB1D] (Mus musculus) PubMed

 4425.

cytosolic dihydroorotate dehydrogenase is involved in plant stress response and that OsDHODH1 could be used in engineering crop plants with enhanced tolerance to salt and drought[cytosolic dihydroorotate dehydrogenase (DHODH)] (Mus musculus) PubMed

 4426.

ZFP245 may contribute to the tolerance of rice plants to cold and drought stresses by regulating proline levels and reactive oxygen species-scavenging activities.(ZFP245) (Mus musculus) PubMed

 4427.

OsMADS14 is activated by FLOWERING LOCUS T 1 (RFT1) protein in the shoot apical meristem after the transition to flowering.[RFT1] (Mus musculus) PubMed

 4428.

show that the FLORAL ORGAN NUMBER2 (FON2) SPARE1 (FOS1) gene encoding a CLE protein functions along with FON2 in maintenance of the floral meristem.[FLORAL ORGAN NUMBER2(FON2) and FON2 SPARE1] (Mus musculus) PubMed

 4429.

KHA1 can be classified as an Na(+)/H(+) transporter [KHA1] (Mus musculus) PubMed

 4430.

Two major K+ uptake systems were cloned and characterized. [TRK1p, HAK1p] (Mus musculus) PubMed

 4431.

Alkyy hydroperoxide reductase plays a key role in adaption to high salinity by scavenging ROS, serving as chaperone and mediating H2O2-mediated defense signaling. [AHP] (Mus musculus) PubMed

 4432.

NRG1 (GENBANK# DQ641949)mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans [Nrg1] (Mus musculus) PubMed

 4433.

C. neoformans may have a limited requirement for Cch1 and that this requirement appears to include ion stress tolerance [cch1] (Mus musculus) PubMed

 4434.

Four members of the C. neoformans (H99)catalase gene family were identified - CAT1 and CAT3 encode putative spore-specific catalases, CAT2 encodes a putative peroxisomal catalase, and CAT4 encodes a putative cytosolic catalase: CAT1, CAT2, CAT3 and CAT4. (Mus musculus) PubMed

 4435.

Study shows that a Cryptococcus neoformans Hsp70 homologue Ssa1 is a DNA-binding transcriptional co-activator of laccase by binding to a GC-rich element within the 5'-UAS in response to glucose starvation, iron, copper, calcium and temperature. (Mus musculus) PubMed

 4436.

results suggest that SXI1alpha and SXI2a coordinately control uniparental mitochondrial inheritance in C. neoformans [SXI1 alpha SXI2a] (Mus musculus) PubMed

 4437.

Cdc24 is a Ras1 effector in C. neoformans to mediate the ability of this fungus to grow at high temperature and to cause disease [CDC24] (Mus musculus) PubMed

 4438.

C. neoformans produces two GDP-mannose transporters to satisfy its enormous need for mannose utilization in glycan synthesis.[GMT1, GMT2] (Mus musculus) PubMed

 4439.

Eca1 which encodes a sarcoplasmic/endoplasmic reticulum (ER) Ca2+-ATPase (SERCA)-type calcium pump is likely involved in maintaining ER function, thus contributing to stress tolerance and virulence acting in parallel with Ca2+-calcineurin signaling. (Mus musculus) PubMed

 4440.

Based on the phenotype of dominant active alleles, Gpa2 and Gpa3 signal in opposition: Gpa2 promotes mating, whereas Gpa3 inhibits.[Gpa2, Gpa3] (Mus musculus) PubMed

 4441.

Laccases utilizes both L- and D-DOPA at a similar rate in melanin synthesis. [Laccase] (Mus musculus) PubMed

 4442.

Results show that the repression of EF3 led to the mislocalization of Cch1, suggesting a role for EF3 in targeting Cch1 to the plasma membrane of C. neoformans.[EF3,Cch1 in strain H99] (Mus musculus) PubMed

 4443.

Deletion of PKC1 shows that this gene is essential for defense against both oxidative and nitrosative stresses; however, other genes involved directly in the PKC1 pathway are dispensable for protection against these stresses.[PKC1] (Mus musculus) PubMed

 4444.

The authors conclude that Crg2 participates in controlling both Gpa1-cAMP-virulence and pheromone-mating signaling cascades.[Crg2 in strain CDX40] (Mus musculus) PubMed

 4445.

In animal models the phenotype of the all1Delta mutant mimicked the hypervirulent phenotype of the mucoid switch variant, which is characterized by decreased host survival and elevated intracranial pressure.[ALL1] (Mus musculus) PubMed

 4446.

The crystal structure of Can2 reveals that the enzyme belongs to the "plant-type" beta-carbonic anhydrase (CAs) but carries a unique N-terminal extension that can interact with the active-site entrance of the dimer.[Can2] (Mus musculus) PubMed

 4447.

Subcellular localization ras1 protein dictates its downstream signaling specificity. [Ras1] (Mus musculus) PubMed

 4448.

The authors showed that the AFR1-overexpressing mutant strain was not sensitive to microglia-mediated anticryptococcal activity, as compared with the wild type and the afr1Delta mutant.[AFR1 in strain BPY22] (Mus musculus) PubMed

 4449.

Disruption of CUF1 demolished the activation of LAC1 transcription by copper, whereas the reconstituted strain restored the phenotypic defects.[CUF1] (Mus musculus) PubMed

 4450.

Deletion of vtc4 in U. maydis reduced proliferation in host plants and polyphosphate (polyP) stored in vacuoles revealing a novel role for PKA-regulated polyP accumulation in fungal morphogenesis and virulence [vtc4p] (Mus musculus) PubMed

 4451.

Biz1 is involved in cell cycle arrest preceding plant penetration as well as in the induction of appressoria. (Mus musculus) PubMed

 4452.

The Clp1 protein facilitates cell cycle progression during hyphal growth. [CLP1] (Mus musculus) PubMed

 4453.

Don3 kinase exerts a dual function in the regulation of cell separation and nuclear envelope breakdown [Don3] (Mus musculus) PubMed

 4454.

cooperation between BRC and CRE domains and the Dss1-provoked dissociation of Brh2 complexes are requisite features of Brh2's molecular mechanism [Dss1][Brh2] (Mus musculus) PubMed

 4455.

Cdk5 is essential for growth, maintenance of cell polarity, and full virulence in U. maydis [Cdk5] (Mus musculus) PubMed

 4456.

These results suggest that U. maydis is using its Yap1-controlled H(2)O(2) detoxification system for coping with early plant defense responses.[Yap1] (Mus musculus) PubMed

 4457.

the role of the putative U. maydis BCCIP ortholog Bcp1 in DNA repair and recombination (Mus musculus) PubMed

 4458.

Rad52 serves in an overlapping, compensatory role with both Rec2 and Brh2 to promote and maintain formation of the Rad51 nucleoprotein filament.[Rad52] (Mus musculus) PubMed

 4459.

In vitro GDP/GTP exchange assays demonstrated that Don1 is highly specific for Cdc42 and cannot activate Rac1.[Don1, Cdc42] (Mus musculus) PubMed

 4460.

fuz1 is necessary for cell morphogenesis of the Ustilago maydis. [Fuz1] (Mus musculus) PubMed

 4461.

This study revealed that transcriptional regulation of prf1 had only minor influence on target gene expression stressing the importance of post-translational control.(Prf1) (Mus musculus) PubMed

 4462.

Absence of Spa2 does not affect cytoskeleton organization and pathogenicity.[Spa2] (Mus musculus) PubMed

 4463.

Bem1 and Cdc24 physically interact and colocalize at cell tips and that Cdk5 regulates this interaction.[Bem1, Cdc24, Cdk5] (Mus musculus) PubMed

 4464.

Endosomal compartmentalization of a Cdc42-specific exchange factor is involved in the coordination of cytokinesis and cell separation.[Don1] (Mus musculus) PubMed

 4465.

Lga2 in conjunction with Rga2 directs uniparental mtDNA inheritance by mediating loss of the a1-associated mtDNA.[lga2][rga2] (Mus musculus) PubMed

 4466.

Rep1-1 filaments decrease in length at increasing concentrations[Rep1] (Mus musculus) PubMed

 4467.

Brh2 can pair the displaced strand of a D loop with a complementary single-stranded DNA to form a duplexed, or double, D loop. (Mus musculus) PubMed

 4468.

The expression of ena1 and ena2 transcripts in U. maydis was enhanced at high pH and at high K(+) and Na(+) concentrations. [ENA1, ENA2] (Mus musculus) PubMed

 4469.

The rok1 dual specificity MAPK phosphatase regulates the activity of Kpp2 as well as of Kpp6. [Rok1] (Mus musculus) PubMed

 4470.

The a2 mating-type-locus gene lga2 of Ustilago maydis interferes with mitochondrial dynamics and fusion, partially in dependence on a Dnm1-like fission component. (Mus musculus) PubMed

 4471.

The authors identified the Ustilago maydis gene, cco1, encoding a putative beta-carotene cleavage oxygenase. (Mus musculus) PubMed

 4472.

Spe-Sdh mutants were sensitive to stress, unable to carry out the yeast-to-mycelium dimorphic transition, and showed attenuated virulence to maize.[Spe-Sdh] (Mus musculus) PubMed

 4473.

Template switching promoted by Brh2 provides a mechanism for recombination-mediated bypass of lesions blocking synthesis during DNA replication.[Brh2] (Mus musculus) PubMed

 4474.

A single Candida albicans transcription factor gene UPC2 that regulates sterol metabolism. (Mus musculus) PubMed

 4475.

Residue of H310 was important to the function of CYP51. [CYP51] (Mus musculus) PubMed

 4476.

results suggest that Ecm33p is required for normal cell wall architecture as well as normal function and expression of cell surface proteins in C. albicans [ecm33] (Mus musculus) PubMed

 4477.

This involvement of SST2 in the sensitivity to pheromone is consistent with the prediction that the mating response pathway in C. albicans requires the activation of a heterotrimeric G protein [SST2] (Mus musculus) PubMed

 4478.

Tac1p is a transcription factor regulating CDR1 and CDR2, and its mutation is associated with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans [Tac1p, CDR2] (Mus musculus) PubMed

 4479.

the fungal pathogen Candida albicans carries an 899-residue stress-inducible orthologue of Hsp104 (CaHsp104) that shows a high degree of amino acid identity to S. cerevisiae Hsp104 [Hsp104] (Mus musculus) PubMed

 4480.

identification and disruption of RAC1, and show that, in contrast to CDC42, it is not necessary for viability or serum-induced hyphal growth but is essential for filamentous growth when cells are embedded in a matrix [rac1 & cdc42] (Mus musculus) PubMed

 4481.

N-acetylglucosamine-phosphate mutase (AGM1) was purified and crystallized. The crystals diffract X-rays to beyond 1.8 angstroms resolution using synchrotron radiation. (AGM1) (Mus musculus) PubMed

 4482.

two ORFs, CaFAD2 & CaFAD3, were identified based on homology to other yeast fatty acid desaturases; results strongly supported that CaFAD2 encodes the Delta12 fatty acid desaturase and that CaFAD3 encodes the omega3 fatty acid desaturase [FAD2, FAD3] (Mus musculus) PubMed

 4483.

C. albicans Ssa2p facilitates fungicidal activity of Hst 5 in binding and intracellular translocation, whereas Ssa1p appears to have a lesser functional role in Hst 5 toxicity [Ssa1p, Ssa2p] (Mus musculus) PubMed

 4484.

These results support the hypothesis that the Grr1 protein of C. albicans, presumably as the F-box subunit of an SCF ubiquitin ligase, has an essential role in preventing the switch from the yeast cell morphology to a pseudohyphal morphology.[GRR1] (Mus musculus) PubMed

 4485.

PDR16 plays a role in C. albicans azole resistance.(PDR16) (Mus musculus) PubMed

 4486.

Multiple transcription factors control expression of the MDR1 efflux pump and mutations that cause constitutive MDR1 overexpression and drug resistance affects the activities of several of these transcription factors. [MDR1] (Mus musculus) PubMed

 4487.

results indicate that CaBud6 plays an important role in the polarized growth of C. albicans [Bud6] (Mus musculus) PubMed

 4488.

BCR1 pathway functions in vivo to promote biofilm formation; known adhesin Hwp1 also contributes to biofilm formation [BRC1 and Hwp1] (Mus musculus) PubMed

 4489.

The resistant strains experimentally induced after fluconazole exposure in vitro were associated mainly with up-regulation of ERG11 gene. [ERG11] (Mus musculus) PubMed

 4490.

an essential role for the conserved Ras association (RA) domain-mediated Ras1-Cdc35 interaction in raising cellular cAMP levels for hyphal morphogenesis [CDC35, RAS1] (Mus musculus) PubMed

 4491.

simple model can account for both the heritability of the white and opaque states and the stochastic nature of the switching between them [Wor1] (Mus musculus) PubMed

 4492.

present genetic evidence for feedback regulation of WOR1 transcription[WOR1] (Mus musculus) PubMed

 4493.

Fcy21 is efficient high-affinity, high-capacity, purine transporter equal to AzgA from Aspergillus nidulans (Fcy21). (Mus musculus) PubMed

 4494.

alanyl-tRNA synthetase has evolved an unusual pattern of translation initiation and protein partitioning and codes for protein isoforms that can aminoacylate isoaccepting tRNAs from a different species and from across cellular compartments [ALA1] (Mus musculus) PubMed

 4495.

the TR region of Als5p modulated the structure of the Ig-T region, augmented cell adhesion activity through increased binding to mammalian ligands, and simultaneously promoted fungal cell-cell interactions.[Als5] (Mus musculus) PubMed

 4496.

findings show that Cka2p governs the interactions of C. albicans with endothelial and oral epithelial cells in vitro and virulence during oropharyngeal candidiasis [casein kinase II subunit alpha] (Mus musculus) PubMed

 4497.

TOS9, exhibited an expression pattern consistent with a "master switch gene." TOS9 was only expressed in opaque cells, and its gene product, Tos9p, localized to the nucleus.[Tos9] (Mus musculus) PubMed

 4498.

Endogenous Rim101 directly binds to the alkaline-pH-repressed gene PHR2, and the activity is governed not only by proteolytic processing but also by an additional mechanism not previously described: Rim101. (Mus musculus) PubMed

 4499.

Results identify a novel protein that interacts with CaTup1p, named Tcc1p (Tup1p complex component) [Tcc1] (Mus musculus) PubMed

 4500.

Deletions of VPS28 and VPS32 increase the susceptibility of C. albicans to cell wall disruption agents, echinocandin and azole antifungal agents. [Vps32] (Mus musculus) PubMed

 4501.

the Vac1p protein is required for several cellular pathways, in particular those that control virulence and pathogenicity. [Vac1p] (Mus musculus) PubMed

 4502.

This finding provides additional support for the model that Hwp1 is critical for biofilm adhesion. (Mus musculus) PubMed

 4503.

In this study, the role of amino acid residues in the Ssk1p receiver domain was investigated by constructing point mutants at positions of protein phosphorylation [Ssk1p] (Mus musculus) PubMed

 4504.

Cap1 has a significant role in redox status regulation, energy metabolism and substance transport (Cap1). (Mus musculus) PubMed

 4505.

These results implicate Drg1p in the control of invasive filamentation in the laboratory, and in the progression of invasive disease in the host.[DRG1] (Mus musculus) PubMed

 4506.

characterization of the cis-acting regulatory elements present in the MDR1 promoter [MDR1] (Mus musculus) PubMed

 4507.

Proteomic comparison of plasma membrane proteins from buds and from hyphae induced by GlcNAc identified a novel hyphal protein (Ngt1) with similarity to the major facilitator superfamily of transporters. (Mus musculus) PubMed

 4508.

These studies are the first to identify proteins that bind to a DNA segment that confers developmental gene regulation in C. albicans and suggest a new model for hypha-specific gene regulation.[Hwp1, Nhp6, Gcf1p] (Mus musculus) PubMed

 4509.

Study identified and characterized a functional Candida albicans homolog (CaTCO89) of ScTCO89, which encodes a protein of 708 amino acids that shows overall 15% identity with ScTco89p at the amino acid level.[TCO89 protein] (Mus musculus) PubMed

 4510.

We report here that the DNA helicase Hmi1p plays a crucial role in mtDNA stability in Candida albicans. [CaHm1p] (Mus musculus) PubMed

 4511.

C. albicans invades mucosal tissues by promoting the proteolytic degradation of E-cadherin in epithelial adherens junctions, mediated by transcription factor Rim101 and Sap5 proteins. [Rim101, Sap5] (Mus musculus) PubMed

 4512.

The role of two previously uncharacterized Rho proteins, encoded by the Candida albicans RHO3 (CaRHO3) and CaCRL1/CaRHO4 genes, is investigated.[Rho3, Rho4] (Mus musculus) PubMed

 4513.

These results demonstrate that the GATA transcription factors GLN3 and GAT1 control expression of the MEP2 ammonium permease and that GLN3 is also an important regulator of nitrogen starvation-induced filamentous growth in C. albicans.[Mep2, Gln3, Gat1] (Mus musculus) PubMed

 4514.

These data suggest that DOA1 of C. albicans, like its orthologue in S. cerevisiae, is associated with ubiquitin-mediated proteolysis and has multiple functions. [DOA1 protein] (Mus musculus) PubMed

 4515.

Results illustrate an association between Eap1p-mediated adhesion and biofilm formation in vitro and in vivo [Eap1]. (Mus musculus) PubMed

 4516.

CaAbp1 and CaPan1 were found to localize at the cortex and at hyphal tips in a patch-like manner, supporting their role in endocytosis [Abp1, Pan1] (Mus musculus) PubMed

 4517.

Structural comparison with previously determined structures of the enzyme.ligand complexes of other orthologue allowed modeling of the binding of four different inhibitors into the active site of lumazine synthase from Candida albicans [lumazine synthase] (Mus musculus) PubMed

 4518.

homozygous null mutant in a mouse model of systemic candidiasis displayed strongly reduced pathogenicity compared with parental or heterozygous strains. [ATC1] (Mus musculus) PubMed

 4519.

It was found that a C. albicans fatty acid desaturase homolog (Ole2) and a multicopper oxidase homolog (Fet3) play roles in prostaglandin production. [Fet3] (Mus musculus) PubMed

 4520.

Data demonstrate functional homology of Hmt1 between C. albicans and S. cerevisiae: CaHmt1 supports growth of S. cerevisiae strains that require Hmt1, and CaHmt1 methylates Npl3, a major Hmt1 substrate, in S. cerevisiae [Hmt1]. (Mus musculus) PubMed

 4521.

For the yeast prion Sup35, we find that the switch to the prion state is controlled with exquisite specificity by small elements of primary sequence [Sup35] (Mus musculus) PubMed

 4522.

These results reveal that C. albicans hyphal development occurs through Sec3p-independent and dependent phases, and provide strong genetic and biochemical evidence for a role of septins in polarized exocytosis. (Mus musculus) PubMed

 4523.

VPS4 is required for vacuolar biogenesis and proper sorting of vacuolar proteins [VPS4, no strain name] (Mus musculus) PubMed

 4524.

They knocked out both alleles of an ortholog of BCR1, a gene encoding a transcription factor known to be required for biofilm development in C. albicans. They show that C. parapsilosis BCR1 is necessary for biofilm development in C. parapsilosis (Mus musculus) PubMed

 4525.

Cargt1 mutations cause cells to hyperfilament, and suppress the hypofilamented phenotype of an hgt4 mutant, indicating that the Hgt4 glucose sensor may affect filamentation by modulating sugar import and metabolism via CaRgt1.[Rgt1] (Mus musculus) PubMed

 4526.

The effects of the deletion of PDE2 is investigated by genome-wide transcriptome profiling. (Mus musculus) PubMed

 4527.

ALS5 alleles had 2-10 tandem repeat sequence copies while ALS6 alleles had 2-8 copies: [ALS5] and [ALS6] (Mus musculus) PubMed

 4528.

One gene, upregulated in both reconstituted human oral epithelium infection and patients, named EED1, was essential for maintenance of hyphal elongation.[EED1] (Mus musculus) PubMed

 4529.

Candida albicans yeast forms deleted for ALS5, ALS6 or ALS7 are more adherent than a relevant control strain to human vascular endothelial cell monolayers and buccal epithelial cells. [ALS5, ALS6, ALS7] (Mus musculus) PubMed

 4530.

Results provide evidence that Cdc28/Hgc1 may act to prevent Rga2 from localizing to hyphal tips, leading to localized Cdc42 activation for hyphal extension [Rga2, Hgc1]. (Mus musculus) PubMed

 4531.

This study of Gfa1p focuses on the features that distinguish it from the prokaryotic homologue in terms of quaternary structure, control of the enzymatic activity and details of the isomerase active site.[Gfa1] (Mus musculus) PubMed

 4532.

Sfl1 is a negative regulator of hyphal development in C. albicans. (Mus musculus) PubMed

 4533.

A connection between actin structures and the cAMP signaling pathway was shown using hyper- and hypomorphic cAMP mutants, providing a possible mechanism for up-regulation of HWP1 gene expression by stabilized actin.[HWP1] (Mus musculus) PubMed

 4534.

The HOG stress response pathway likely represents a significant and effective challenge to physiological levels of Hst 5 and other toxic peptides in fungal cells.[Hog1] (Mus musculus) PubMed

 4535.

These results suggest that Sfl1 functions in the repression of flocculation and filamentation and thus represents a novel negative regulator of C. albicans morphogenesis.[Sfl1] (Mus musculus) PubMed

 4536.

CZF1 binds CZF1 promoter DNA in vitro and promotes the switch from white to opaque. [CZF1] (Mus musculus) PubMed

 4537.

Ssk2 is the sole MAPKKK to relay stress signals to Hog1 in C. albicans [Hog1, Ssk2 and Pbs2] (Mus musculus) PubMed

 4538.

Sun41 is required for biofilm formation and normal caspofungin tolerance. Sun41 is required for inducing disease.[Sun41] (Mus musculus) PubMed

 4539.

Results show that PDR16 expression in Candida albicans was controlled by zinc cluster transcription factor Tac1p [PDR16 and Tac1p] (Mus musculus) PubMed

 4540.

These results show that Tac1p binds under nonactivating conditions to the promoters of its targets, including to its own promoter.[Tac1] (Mus musculus) PubMed

 4541.

Here, we demonstrate that the Rim101/PacC pH-sensing pathway acts in parallel to Crz1, via calcineurin, to adapt to alkaline pH. [Rim101, Crz2, calcineurin] (Mus musculus) PubMed

 4542.

results suggest that MET6 is essential, and a double deletion is lethal [MET6] (Mus musculus) PubMed

 4543.

GLN3 was an activator of two genes involved in ammonium assimilation, GDH3, encoding NADP-dependent glutamate dehydrogenase, and MEP2, which encodes an ammonium permease. [GLN3 in strain CAI-4] (Mus musculus) PubMed

 4544.

the surface-expressed CaGpm1p is a virulence factor that utilizes the host Factor H, FHL-1, and plasminogen for immune evasion and degradation of extracellular matrices [CaGpm1p] (Mus musculus) PubMed

 4545.

Site-directed mutagenesis indicates that T929G (Gly310Val) substitution is responsible for the non-functionality of the encoded enzyme.[HIS4 in strain CAI-4] (Mus musculus) PubMed

 4546.

we have identified a zinc cluster transcription factor, designated as MRR1 (multidrug resistance regulator), that was coordinately upregulated with MDR1 in drug-resistant, clinical C. albicans isolates. (Mus musculus) PubMed

 4547.

the main function of ascomycetous Sun proteins appears linked to cell wall remodelling, with a probable role in counter-balancing cell wall degradation to avoid cell lysis upon cell separation.[SUN41, SUN42] (Mus musculus) PubMed

 4548.

Our data clearly show that both ergosterol and sphingolipids are essential for selectively recruiting CaDCr1p, over CaMdr1p, to the membrane rafts and that any imbalance in the raft lipid constituents results in missorting of CaCdr1p. [Cdr1p, Mdr1p] (Mus musculus) PubMed

 4549.

Expression of EFH1 regulated the level of colonizing fungi, favoring commensalism as opposed to candidiasis. (Mus musculus) PubMed

 4550.

Large fragments of Als5p contained the conserved amyloid-forming sequence and it formed amyloid-like fibers and bound Congo red under native conditions.[Als5] (Mus musculus) PubMed

 4551.

Deletion mutation was used to determine the role of SSK2 and it was found to be involved in osmotic and oxidative stress.[SSK2] (Mus musculus) PubMed

 4552.

Study reports the characterization of the three predicted Carnitine acetyltransferases genes in C. albicans, CTN1, CTN2 and CTN3.[CTN1, CTN2, CTN3] (Mus musculus) PubMed

 4553.

The effect of deleting G-protein-coupled receptor 1 (GPR1) and trehalose-6-phosphate (T6P) phosphatase (TPS2) on the virulence of C. albicans in mice is reported.[GPR1; TPS2] (Mus musculus) PubMed

 4554.

Our results demonstrate that both increased CDR1 transcription and enhanced CDR1 mRNA stability contribute to the overexpression of CDR1 in azole resistant C. albicans isolates. (Mus musculus) PubMed

 4555.

The X-ray crystal structures of the apoenzyme of Sap1 and Sap5 in complex with pepstatin A at 2.05 and 2.5 A resolution are reported.(Sap1)(Sap5) (Mus musculus) PubMed

 4556.

Upc2p is a key regulator of ergosterol metabolism. (Mus musculus) PubMed

 4557.

These results reveal that the eIF5B in Candida albicans has a close functional relationship with that of Sacharomyces cerevisiae, as also shown by a phylogenetic analysis based on the amino acid sequences of the eIF5Bs.[eIFB] (Mus musculus) PubMed

 4558.

protein kinase Psk1 is required for expression of SKO1 and of Sko1-dependent genes in response to caspofungin [Psk1] (Mus musculus) PubMed

 4559.

Rbt5and Rbt51 facilitate the rapid endocytosis of haemoglobin into the C. albicans vacuole. [Rbt5, Rbt51] (Mus musculus) PubMed

 4560.

HSP12 is regulated by CO2 via a cAMP-dependent mechanism.[hsp12] (Mus musculus) PubMed

 4561.

CCAAT binding factor (CBF) is essential for FRP1 expression in iron-limited environments and FRE2 and FRP1 are both induced directly by the Rim101 transcription factor [CBF, FRP1,FRP2,Rim101] (Mus musculus) PubMed

 4562.

The present findings provide evidence that DDR48 is essential for filamentation, stress response, and possibly viability of C. albicans.[DDR48] (Mus musculus) PubMed

 4563.

These results demonstrate that mutations in MRR1 are the major mechanism of MDR1 overexpression in fluconazole-resistant strains and that MRR1 plays a central role in the development of drug resistance in C. albicans.(MRR1) (Mus musculus) PubMed

 4564.

Rac1 activation by the guanine nucleotide exchange factor Dck1 is required for invasive filamentous growth in the pathogen Candida albicans [Dck1, Rac1] (Mus musculus) PubMed

 4565.

Loss of Kar3p led to defects in nuclear division, causing cells to grow slowly and exhibit reduced viability compared to wild-type cells. [Kar3] (Mus musculus) PubMed

 4566.

The disruption of RTA2 increased the susceptibility of C. albicans to azoles. (RTA2) (Mus musculus) PubMed

 4567.

The presence of an inorganic phosphate in the crystallographic structure opposite the known AMP binding site relative to the thiamine moiety suggests that a second AMP molecule could be accommodated in the C. albicans structure.[TPK] (Mus musculus) PubMed

 4568.

MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans (Mus musculus) PubMed

 4569.

Galpha and Gbeta subunits do not act antagonistically but, instead, are both required for the transmission of the mating signal. [Cag1, Ste4] (Mus musculus) PubMed

 4570.

present the crystal structure of GGTase-I from C. albicans (CaGGTase-I) in complex with its cognate lipid substrate, geranylgeranylpyrophosphate[geranylgeranyltransferase-I alpha and beta subunit] (Mus musculus) PubMed

 4571.

C-terminal signals regulate the protein targeting of Ecm331 and Hwp1 to the cell wall or plasma membrane. [Ecm331, Hwp1] (Mus musculus) PubMed

 4572.

RTA2 is involved in calcineurin-mediated azole resistance and sphingoid long-chain base release in C. albicans. (Mus musculus) PubMed

 4573.

Complement receptor 3 related protein (CR3-RP) has immunomodulatory properties and a role in the adherence of Candida albicans in vitro (using the model systems of buccal epithelial cells) and biofilm formation. [CR3-RP] (Mus musculus) PubMed

 4574.

C. albicans cells lacking the superoxide dismutase Sod5 leads to massive extracellular reactive oxygen species accumulation in vitro, and mutants lacking Sod5 and Sod4 exhibit a severe loss of viability in the presence of macrophages. [Sod4; Sod5] (Mus musculus) PubMed

 4575.

These results suggest that Delta8-desaturation of long-chain bases in ceramides plays a role in the morphogenesis of C. albicans.[delta8-desaturase] (Mus musculus) PubMed

 4576.

In this study the authors demonstrate that ferric reductase FRP1 expression is upregulated by alkaline pH and iron-limited conditions.[FRP1 in strain DAY1] (Mus musculus) PubMed

 4577.

Phenotypic analysis of a methionine-regulated conditional mutant confirmed that Abg1p is involved in endocytosis.[ABG1] (Mus musculus) PubMed

 4578.

findings support models in which Tor1 negatively controls cellular adhesion by governing the activities of Bcr1 and Efg1[Tor1] (Mus musculus) PubMed

 4579.

Hog1 mutants show an enhanced respiratory rate and higher levels of intracellular reactive oxygen species.[Hog1] (Mus musculus) PubMed

 4580.

a three-dimensional model of the C. albicans Met6p based on the known structure of the homologous enzyme from Arabidopsis thaliana was created. (Mus musculus) PubMed

 4581.

Our resutls indicate that Gcf1 protein is a a nonspecific DNA-binding protein involved in mtDNA replication and recombination and thus in fine-tuning mtDNA metabolism. [Gcf1] (Mus musculus) PubMed

 4582.

The iff4 Delta null mutant showed both a decrease of adherence to silicone catheter and a reduction of virulence.[iff4] (Mus musculus) PubMed

 4583.

Bmh1 mutants showed attenuated virulence in a mouse model. [Bmh1] (Mus musculus) PubMed

 4584.

Opposite roles for Tpk1 and Tpk2 isoforms were observed in glycogen storage, suggesting that each of the isoforms has different substrates involved in glycogen regulation. (TPK1) (TPK2) (Mus musculus) PubMed

 4585.

Increased expression generally accompanies Cap1p binding at its targets, indicating that Cap1p functions as a transcriptional activator.[Cap1] (Mus musculus) PubMed

 4586.

Study of crystal structures of the editing domain from 2 eukaryotic cytosolic LeuRS; shows a conserved structural core containing the active site for hydrolysis, with distinct bacterial, archeal, or eukaryotic peripheral insertions.[LeuRS] (Mus musculus) PubMed

 4587.

Rep1p is involved in drug resistance by negatively regulating MDR1 in C. albicans.[Regulator of Efflux Pump 1/REP1] (Mus musculus) PubMed

 4588.

The C. albicans zinc-response transcription factor Zap1 is a negative regulator of a major matrix component, soluble beta-1,3 glucan, in both in vitro and in vivo biofilm models.[Zap1] (Mus musculus) PubMed

 4589.

These data suggest that Chk1p and Sho1p are components of parallel but independent signal pathways.[Chk1] (Mus musculus) PubMed

 4590.

Overexpressing CaSwi1 mitigated invasive and pseudohyphal growth defects resulting from deletions in the MAP kinase and cAMP pathways.[Swi1] (Mus musculus) PubMed

 4591.

The authors show that Cek1 phosphorylation is regulated by quorum sensing. (Mus musculus) PubMed

 4592.

Auxotrophy of strain S4B3008 is due to a mutation of the ADE5 gene encoding a phosphoribosylamine-glycine ligase. (ADE5) (Mus musculus) PubMed

 4593.

The reconstitution of Gibberella zeae PKS13, which is the nonreducing PKS associated with zearalenone biosynthesis, is reported.[PKS13] (Mus musculus) PubMed

 4594.

Putative pheromone precursor genes (ppg1 and ppg2) and their corresponding pheromone receptor genes (pre2 and pre1) were identified in the genomic sequence of G. zeae. [pre2, pre1, ppg1, ppg2] (Mus musculus) PubMed

 4595.

SNF1 is critical for normal sexual and asexual development in addition to virulence and the utilization of carbon sources. [SNF1] (Mus musculus) PubMed

 4596.

data show that one of the mechanisms conferring in vitro-induced benznidazole resistance to T. cruzi correlates with deletion of copies of the TcOYE gene [OYE] (Mus musculus) PubMed

 4597.

The identification and characterization of TcrPDEB1 and its comparison with the previously identified TcrPDEB2 (formerly known as TcPDE1), is reported. (Mus musculus) PubMed

 4598.

Tc-1 is a cell surface casein kinase II (CKII) substrate expressed only in invasive trypomastigotes, phosphorylated by human CKII and involved in the early process of cellular infection. (Tc-1) (Mus musculus) PubMed

 4599.

identification, expression, purification, enzyme kinetics, and the role of divalent metal in the ATPase activity of the RNA triphosphatase from Trypanosoma cruzi and compares it with the enzyme from Trypanosoma brucei [RNA triphosphatrase] (Mus musculus) PubMed

 4600.

TcSPPS is a solanesyl-diphosphate synthase localizes in glycosomes of Trypanosoma cruzi [TcSPPS] (Mus musculus) PubMed

 4601.

Our findings show an increased expression of the TcFeSOD-A enzyme in the T. cruzi population with in vitro-induced resistance to benznidazole. (FeSOD-A) (Mus musculus) PubMed

 4602.

The isolation of phospholipase A1 (Plase A1) from Trypanosoma cruzi infective stages and its possible role regarding the interaction with mammalian host cells are reported.[phospholipase A1] (Mus musculus) PubMed

 4603.

overexpression of mitochondrial iron superoxide dismutase, which is also observed during metacyclogenesis, resulted in cytoprotective effects[iron superoxide dismutase] (Mus musculus) PubMed

 4604.

isolation and characterization of a new member of the gp82 family and global analysis on the expression as well as the cellular localization of gp82 proteins in metacyclic forms of the CL and G strains [Gp82] (Mus musculus) PubMed

 4605.

In the case of Tc-SAHH, the final affinity for NAD+ is roughly micromolar and this affinity persists as the equilibrium affinity.[S-adenosylhomocysteine hydrolase] (Mus musculus) PubMed

 4606.

The D80A mutation induces only a slight conformational change in the active site yet results in a significant alteration of nucleotide binding and modifies the ability of the dUTPAse to discriminate between dUTP and dUMP (dUTPase). (Mus musculus) PubMed

 4607.

In summary, we found that few strains can express different isoforms of Amastigote Surface Protein 2 (ASP-2) which may not share cross-protective epitopes. [ASP-2] (Mus musculus) PubMed

 4608.

Complementation experiments showed that the intact calmodulin-ubiquitin (cub) gene is necessary for full expression of virulence [cub] (Mus musculus) PubMed

 4609.

Can utilize both L-galactono-gamma-lactone and D-arabinono-gamma-lactone as substrates for synthesis of vitamin C. (galactonolactone oxidase; galactonolactone dehydrogenase; GLDHase) (Mus musculus) PubMed

 4610.

We demonstrated that three subfamilies of gp82 were in the genome of T. cruzi and maintained their functional structure, and that the mRNA expressions of those genes were equally controlled in a stage-specific manner.[pg82] (Mus musculus) PubMed

 4611.

The unfolding transition of triosephosphate isomerase was found to be highly irreversible even at the very early stages of the reaction(triosephosphate isomerase). (Mus musculus) PubMed

 4612.

The compartmentalization switch of LYT1 results in two surprisingly different functions: haemolytic activity at acid pH for mLYT1, and a putative involvement in mitochondrial metabolism for kLYT1.[LYT1] (Mus musculus) PubMed

 4613.

Study reports the cloning, expression, purification, and characterization of the exopolyphosphatase TcPPX gene The product of this gene, has 383 amino acids and a molecular mass of 43.1 kDa.[PPX] (Mus musculus) PubMed

 4614.

To define similarities and differences with the human pair, we performed a detailed alanine scan analysis that allowed us to identify the regions and the critical amino acids of T. cruzi SF3b155 involved in interaction with p14[SF3b155] (Mus musculus) PubMed

 4615.

This study was conducted to characterize the infective behavior of the LYT1 deletion stratin, T. cruzi L16, in the insect vector and murine models.[LYT1] (Mus musculus) PubMed

 4616.

TcPUF6 regulates the half-lives of its associated transcripts via differential association with mRNA degradation complexes throughout its life cycle[PUF6] (Mus musculus) PubMed

 4617.

Results describe the expression of markers on dendritic cells from chronic chagasic patients stimulated with the KMP-11 protein and the K1 peptide from Trypanosoma cruzi [Kmp-11]. (Mus musculus) PubMed

 4618.

Results describe polymorphisms in the genes in Colombian strains of Trypanosoma cruzi [trypanothione reductase, cruzipain]. (Mus musculus) PubMed

 4619.

The crystal structure of dihydroorotate dehydrogenase (DHODH) from T. cruzi strain Y solved at 2.2A resolution was reported. (Mus musculus) PubMed

 4620.

The binding of NAD (+) and NADH in SAHH appears structurally to be mediated by helix 18, formed by seven residues near the C-terminus of the adjacent subunit [SAHH] (Mus musculus) PubMed

 4621.

first detailed characterization of the Trypanosoma cruzi actin [actin] (Mus musculus) PubMed

 4622.

study reports the purification, partial biochemical characterization and subcellular localization of a T. cruzi secreted 75 kDa serine oligopeptidase from the axenic epimastigote forms [75 kDa serine oligopeptidase] (Mus musculus) PubMed

 4623.

The role of complement C2 receptor inhibitor trispanning gene (CRIT) in the resistance of 2 strains of T. cruzi to complement-mediated lysis is reported.[CRIT] (Mus musculus) PubMed

 4624.

TcVps34 plays a prominent role in vital processes for T. cruzi survival such as osmoregulation, acidification, and vesicular trafficking[TcVps34] (Mus musculus) PubMed

 4625.

Our findings demonstrate increased expression of the cytosolic and mitochondrial Tryparedoxin peroxidase (TXNPx) in the T. cruzi population with in-vitro-induced resistance to benznidazole. (Mus musculus) PubMed

 4626.

TcCRT participates in the induction of cardiac autoimmunity in Chagas' disease.[calreticulin] (Mus musculus) PubMed

 4627.

TcSBDS contains a C-terminal extension of 200 amino acids that displays the features of intrinsically disordered proteins as determined by proteolytic, circular dichroism and NMR analyses. (TcSBDS, accession number EU715774) (Mus musculus) PubMed

 4628.

As papain exhibits high structural similarity to the catalytic domain of the T. cruzi enzyme cruzipain, the present chagasin-papain complex provides a reliable model of chagasin-cruzipain interactions[chagasin] (Mus musculus) PubMed

 4629.

These findings strongly support a key role for classical and novel protein kinase C isoenzymes in the signaling pathways involved in Trypanosoma cruzi metacyclogenesis induced by oleic acid.[protein kinase C in strain RA] (Mus musculus) PubMed

 4630.

The dynamics of Tc38 subcellular localization observed during the cell cycle and life stages support a major role for Tc38 related to kDNA replication and maintenance.[Tc38] (Mus musculus) PubMed

 4631.

These results show that GP63 is expressed at all life stages and that individual isoforms play a role in host cell infection. (Mus musculus) PubMed

 4632.

The interaction between U2AF35 and U2AF65 was very weak or not detectable. However, as in other eukaryotes, the interaction between U2AF65 and SF1 was strong.[U2AF35,U2AF65 and SF1] (Mus musculus) PubMed

 4633.

Dispersed Gene Family-1 (DGF-1) members, comprising the third largest T. cruzi specific gene family, have conserved adhesin motifs including four segments with significant similarity to human beta 7 integrin [Dispersed Gene Family-1] (Mus musculus) PubMed

 4634.

KAP4 and KAP6 exhibit differential distribution in the kinetoplast of distinct developmental stages. [KAP4;KAP6] (Mus musculus) PubMed

 4635.

These data demonstrate that prozyme mediated activation of S-adenosylmethionine decarboxylase is a common mechanism required to regulate S-adenosylmethionine decarboxylase activity in the trypanosomatids.[prozyme] (Mus musculus) PubMed

 4636.

characterization of SHSP16;recombinant SHSP16 showed molecular chaperone activity in vitro [SHSP16] (Mus musculus) PubMed

 4637.

Preliminary X-ray analysis of aspartate transcarbamoylase from Trypanosoma cruzi at 2.8 A resolution, is reported.[Aspartate transcarbamoylase] (Mus musculus) PubMed

 4638.

The data show that the establishment of a disulfide bridge between two C202 of two dimeric Triosephosphate isomerase from the mesophile Giardia lamblia, accounts for multimerization. (Mus musculus) PubMed

 4639.

The crystal structures of the apo and Ca(2+)-bound forms of alpha-11 giardin, the first alpha giardin to be characterized structurally, is reported.[alpha-11 giardin] (Mus musculus) PubMed

 4640.

isolated as an approximately 35-kDa polypeptide, which was identified by mass spectrometry as a nitroreductase (NR) homologue (EAA43030.1). [GLNR1] (Mus musculus) PubMed

 4641.

The solution structure of a distant variant of ubiquitin, found at the N-terminus of S27a in Giardia lamblia, referred to as GlUb(S27a), is reported.[GlUb(S27a)] (Mus musculus) PubMed

 4642.

The only NST of Giardia (GlNst), which we could identify, transports UDP-GlcNAc in transfected Saccharomyces and is present in perinuclear and peripheral vesicles and increases in expression during encystation. [NST (nucleotide sugar transporter)] (Mus musculus) PubMed

 4643.

Giardia cysteine protease 2 is not only the major cysteine endoprotease expressed in Giardia, but is also central to the encystation process [CP2] (Mus musculus) PubMed

 4644.

These findings reveal a dual role played by ADI and define novel regulatory pathways used by Giardia for survival.[ADI] (Mus musculus) PubMed

 4645.

Alpha-14 giardin exhibits calcium-dependent binding to phospholipids that coordinate cytoskeletal disassembly/assembly during differentiation of the parasite.[Annexin E1] (Mus musculus) PubMed

 4646.

specificity of the oxygen-detoxifying flavodiiron protein towards O2 [flavodiiron protein] (Mus musculus) PubMed

 4647.

Overexpression of ehcp5 but not of ehcp1 or ehcp2 significantly increased amoebic liver abscess formation in laboratory animals supporting the important role of EhCP5 in E. histolytica pathogenicity.[Cysteine proteinase CP5] (Mus musculus) PubMed

 4648.

Expression of a negative dominant version of EhGEF2 protein in E. histolytica provoked a 30% decrease in its ability to phagocyte human erythrocytes as well as severe effects on both the proliferation and the cellular chemotaxis[GEF2] (Mus musculus) PubMed

 4649.

we report the molecular cloning, from E. histolytica genomic DNA, of the genes ehtrxr and ehtrx41, respectively coding for thioredoxin reductase (EhTRXR) and thioredoxin (EhTRX41). EhTRXR)(EhTRX41) (Mus musculus) PubMed

 4650.

This protein, alpha-actinin2, has a N-terminal actin-binding domain, a C-terminal calcium-binding domain and an intervening rod domain containing two spectrin repeats.[alpha-actinin2] (Mus musculus) PubMed

 4651.

Entamoeba Arp2 complements analogous Dictyostelium mutations at all stages of the life cycle [arp2] (Mus musculus) PubMed

 4652.

unfolding and refolding of the Triose phosphate isomerase from Entamoeba histolytica (Mus musculus) PubMed

 4653.

Results provide insight into the structure of Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase [GAPDH]. (Mus musculus) PubMed

 4654.

PAK3 protein from E. histolytica has constitutive activity and has demonstrated a strong involvement in receptor capping (EhPAK3). (Mus musculus) PubMed

 4655.

The lgl4 and -5 subunits (31 kDa) are overexpressed and appear to compensate for the missing lgl1 to -3 in the heterodimer complex.[Lgl4, Lgl5] (Mus musculus) PubMed

 4656.

EhSTIRP thus likely represents a novel determinant of virulence in Entamoeba histolytica.[EhSTIRP] (Mus musculus) PubMed

 4657.

Here we show recombinant EhNst2 (nucleotide-sugar transproter) transports UDP-Glc in transfected Giardia, while recombinant EhNst3 transports UDP-GlcNAc in transfected Saccharomyces. [EhNsSt2, EhNst3] (Mus musculus) PubMed

 4658.

The crystal structure of native O-acetyl-serine sulfhydrylase (OASS) from Entameoba histolytica has been determined at 1.86 A resolution and in complex with its product cysteine at 2.4 A resolution.(OASS) (Mus musculus) PubMed

 4659.

results implicate rhomboid proteases for the first time in immune evasion and suggest that a common function of rhomboid enzymes in widely divergent protozoan pathogens is to break down adhesion proteins.[ROM1 protein (rhomboid protease)]. (Mus musculus) PubMed

 4660.

Our results show that a CD59-like molecule is expressed in trophozoites of E. histolytica found in colonic amebic lesions. [CD59] (Mus musculus) PubMed

 4661.

This gene has a 154 bp intron and encodes for a highly conserved polypeptide. {Ehvma2} (Mus musculus) PubMed

 4662.

Functional studies of nucleotide exchange of Phe314Ala GEF1 mutant showed a decrement of 80% on RacG GTPase.[GEF1] (Mus musculus) PubMed

 4663.

The 3D structure of EhCaBP2 was determined using multidimensional NMR; the protein consists of two globular domains connected by a short flexible linker region of four residues [CaBP2] (Mus musculus) PubMed

 4664.

Oxidase and reductase activities were shown in the protein disulfide isomerase of Entamoeba histolytica. [PDI] (Mus musculus) PubMed

 4665.

cloned, expressed and purified thymidine kinase (Eh-TK) and uridine-cytidine kinase (Eh-UCK). inhibitors or alternate substrates, although partially reduce protozoan proliferation, are reversible [thymidine kinase and uridine-cytidine kinase; no strain] (Mus musculus) PubMed

 4666.

MLBP binds preferentially to the methylated forms of DNA target. [MLBP] (Mus musculus) PubMed

 4667.

These studies demonstrate that PbKch1 contributes to the transport of K(+) in P. berghei parasites and supports the growth of the parasites, in particular the development of oocysts in the mosquito midgut.[Kch1] (Mus musculus) PubMed

 4668.

Study shows that a novel, protein, termed TRAP-like protein (TLP), is a functional members of the TRAP family; TLP is expressed in invasive stages, targeted gene disruption revealed a nonvital role during life cycle progression.[TLP] (Mus musculus) PubMed

 4669.

asparagine-rich protein is a key regulator of Plasmodium sporozoite gene expression and LS development[SLARP] (Mus musculus) PubMed

 4670.

The authors demonstrate that the sporozoite-specific transmembrane protein S6 is required for efficient malaria transmission to the vertebrate host.[S6] (Mus musculus) PubMed

 4671.

UBP-1 (deubiquinating enzyme) gene mutations in artesunate- and chloroquine-resistant rodent malaria parasites. [UBP-1] (Mus musculus) PubMed

 4672.

Genetic polymorphism in T-helper cell epitopic regions of circumsporozoite protein of 148 Plasmodium falciparum isolates from different epidemic and endemic regions of India [circumsporozoite protein] (Mus musculus) PubMed

 4673.

findings suggesting that most malaria in pregnancy arises from parasite adhesion to chondroitin sulfate A in association with expression of the unique epitopes of VAR2CSA[VAR2CSA] (Mus musculus) PubMed

 4674.

crystal structure of beta-hydroxyacyl acyl carrier protein dehydratase of Plasmodium falciparum (PfFabZ) has been determined at a resolution of 2.4 A [FabZ] (Mus musculus) PubMed

 4675.

A study evaluating the synthetic substrate and model inhibitor profiles of FP-2 and FP-3 as well as BP-2 (berghepain-2), an orthologue from the rodent parasite Plasmodium berghei, is presented. (Mus musculus) PubMed

 4676.

Plasmodium falciparum histidine-rich protein II reduces CD69 expression in T cells. [Plasmodium falciparum histidine protein II] (Mus musculus) PubMed

 4677.

The heparin binding site of TRAP-TSR domain is located in the N-terminal half of the structure. The smallest heparin fragment binding to TRAP-TSR is a tetrasaccharide.(Thrombospondin-related anonymous protein) (Mus musculus) PubMed

 4678.

PfORC1 is expressed specifically in the nucleus during the trophozoite and schizont stages of the asexual parasitic life cycle where maximum amount of DNA replication takes place. [ORC1] (Mus musculus) PubMed

 4679.

cloning, overexpression, and characterization of three members of the heat shock family, PfHsp70-1 (an Hsp70 protein with a C-terminal EEVD motif), PfHsp70-2 (an Hsp70 protein without the EEVD motif), and PfHsp70 interacting protein[PfHsp70-1, PfHsp70-2] (Mus musculus) PubMed

 4680.

Gene is not amplificied in Plasmodium falciparum isolated from Guinea-Bissau and Liberisa. [pfmdr1 protein] (Mus musculus) PubMed

 4681.

His-509-Glu-514 dyad, in analogy to those in related oxidoreductases, acts as the acid-base catalyst in Pf thioredoxin reductase [thioredoxin reductase] (Mus musculus) PubMed

 4682.

Pfnek3 was able to phosphorylate and stimulate Pfmap2; the Pfnek3-Pfmap2 interaction may be specific for Pfmap2 regulation(Pfnek3)(Pfmap2) (Mus musculus) PubMed

 4683.

results suggest that P. falciparum requires expression of falstatin to limit proteolysis by certain host or parasite cysteine proteases during erythrocyte invasion (Mus musculus) PubMed

 4684.

The interaction of Plasmodium falciparum EBA-181 with the highly conserved 10 kDa domain of 4.1R provides new insight into the molecular mechanisms utilized by P. falciparum during erythrocyte entry [EBA-181] (Mus musculus) PubMed

 4685.

Primary processing of merozoite surface protein 7 (MSP7) occurs prior to that of MSP1 in a post-Golgi compartment, whereas the secondary cleavage occurs on the surface of the developing merozoite[merozoite surface protein 7} (Mus musculus) PubMed

 4686.

Raf kinase inhibitor protein is recognized as a substrate under in vitro conditions and appears to act as a regulator of calcium-dependent protein kinase 1 kinase activity[Raf kinase inhibitor protein and calcium-dependent protein kinase 1] (Mus musculus) PubMed

 4687.

Study found that the N-terminal 24 amino acids of RhopH2, including signal peptide sequence, were sufficient to target green fluorescent protein to the rhoptries under the rhoph2 promoter. [RhopH2] (Mus musculus) PubMed

 4688.

expression, purification, and characterization of a falcipain-1 construct encoding mature falcipain-1 and 35 amino acids from the C-terminal of the pro domain; results suggest a possible role of falcipain-1 in merozoite invasion [falcipain-1] (Mus musculus) PubMed

 4689.

In these samples from Venezuela, there is a single origin and fixation for both dhfr(dihydrofolate reductase) and dhps (dihydropteroate synthase) Sulfadoxine-Pyrimethamine-resistant alleles. [Dhfr, Dhps] (Mus musculus) PubMed

 4690.

The homologue of mammalian UCHL3 was cloned from both T. gondii and Plasmodium falciparum and it was shown that both enzymes possess deubiquitinating as well as deNeddylating activity.[UCHL3 protein] (Mus musculus) PubMed

 4691.

In this study, a higher level of diversity at microsatellite (MS) loci within the pfcrt gene was observed when compared with the level of diversity at pfcrt flanking MS (Mus musculus) PubMed

 4692.

Pfs48/45 protein consists of a C-terminal six-cysteine module recognized by anti-epitope I antibodies, a middle four-cysteine module recognized by anti-epitopes IIb and III, and an N-terminal module recognized by anti-epitope V antibodies [pfs48/45] (Mus musculus) PubMed

 4693.

2.4-A and 2.7-A structures of P. falciparum aldolase (PfAldo), obtained from crystals grown in the presence of the C-terminal hexapeptide of TRAP from Plasmodium berghei, are described.[Aldolase] (Mus musculus) PubMed

 4694.

Results suggest that PfGCN5 is recruited to the promoter regions of genes to mediate histone acetylation and activate gene expression in P. falciparum [PfGCN5]. (Mus musculus) PubMed

 4695.

The mechanism deduced by product inhibition studies proves that PfLDH shares a common mechanism with the human LDHs, that of an ordered sequential bireactant system with coenzyme binding first.[lactate dehydrogenase] (Mus musculus) PubMed

 4696.

Significant sequence polymorphism was found within repeat regions of PfRh1, PfRh2a, and PfRh2b [PfRH1] (Mus musculus) PubMed

 4697.

the transition-state structures of PfADA, HsADA, and bovine ADA (BtADA) solved using competitive kinetic isotope effects (KIE) and density functional calculations [ADA] (Mus musculus) PubMed

 4698.

Migration of parasites carrying an ancestral triple-mutant dhfr allele drives the spread of dhfr alleles associated with pyrimethamine resistance throughout West and Central Africa.[dihydrofolate reductase] (Mus musculus) PubMed

 4699.

there is no promiscuous transcription of var genes at the individual cell level,and it is possible to correlate dominant transcripts with adhesion phenotype and clinical markers of malaria severity [var] (Mus musculus) PubMed

 4700.

data demonstrate that stage specific promoter activity of the hrp3 gene in P. falciparum blood stage parasites is supported, at least in-part, by a small promoter region that can function in the absence of a larger chromosomal context[hrp3] (Mus musculus) PubMed

 4701.

var gene transcription was analysed in patients dying with falciparum malaria.[var] (Mus musculus) PubMed

 4702.

Lipoproteins, especially those of the low-density lipoprotein fraction, promote PfEMP1 surface presentation. (Mus musculus) PubMed

 4703.

Data suggest that Pfmap-2 is essential for the asexual cycle of P. falciparum, but that Pfmap-1 is not necessary for schizogony and gametocytogenesis in erythrocytes, nor for gametogenesis and sporogony in the mosquito vector [Pfmap-1, -2]. (Mus musculus) PubMed

 4704.

The role of Pfnek3 as a likely upstream MAPK kinase is defined through molecular and biochemical characterization.[Pfnek3] (Mus musculus) PubMed

 4705.

MAEBL.The M2 domain was sequenced from lab isolates and African samples. No evidence of diversifying or positive selection was found in the pattern of base substitutions. (Mus musculus) PubMed

 4706.

The effect of MSP2 polymorphism of P. falciparum on the severity of malaria infections is reported.[MSP2] (Mus musculus) PubMed

 4707.

This study shows that PfSir2 has the appropriate characteristics to be a direct regulator of chromatin structure in P. falciparum.[Sir2] (Mus musculus) PubMed

 4708.

The gene encoding this channel is termed P. falciparum aquaglyceroporin and is a single-copy gene and highly homologous to other aquaporins from other protozoa; only two non-synonymous mutations were found in 65 strains.[AQP] (Mus musculus) PubMed

 4709.

point mutations occur in the dhfr and dhps genes and the presence of combinations of three alleles in dhfr (51Ile, 59Arg and 108Asn) and "quintuple" mutant (dhfr 51Ile, 59Arg, 108Asn and dhps 437Gly, 540Glu). (Mus musculus) PubMed

 4710.

NMR chemical shift perturbation analysis mapped the location of the possible ferredoxin-NADP(+) reductase interaction sites on the surface of ferredoxin(ferredoxin-NADP(+) reductase, ferredoxin). (Mus musculus) PubMed

 4711.

Both P. falciparum protein, reticulocyte homology 4 (PfRH4) and a recombinant protein bind strongly to neuraminidase-treated erythrocytes. (Mus musculus) PubMed

 4712.

The substrate recognition mechanism as well as the rearrangement of the hydrogen bond array at the active site for orotidine 5'-monophoshate decarboxylase were determined (Orotidine 5'-monophoshate decarboxylase). (Mus musculus) PubMed

 4713.

Used x-ray crystal structure of Plasmodium falciparum dihydrofolate reductase (DHFR) to select antimalarials for future high-throughput screening experiments. (Mus musculus) PubMed

 4714.

Release of merozoites from schizonts resulted in the movement of rhomboid-1 protease from the lateral asymmetric localization to the merozoite apical pole and the posterior pole[rhomboid-1 protease] (Mus musculus) PubMed

 4715.

In P. falciparum the para-Nitrophenyl Phosphatase capable to catalyse thiamine monophosphate phosphatase reaction has been identified by analysis of the substrate specificity.[para-Nitrophenyl Phosphatase] (Mus musculus) PubMed

 4716.

Localisation studies show that LplA2 is present in both mitochondrion and apicoplast of Plasmodium falciparum. (Mus musculus) PubMed

 4717.

investigation of PfATPase6 gene polymorphism in seventy-five P. falciparum isolates from imported malaria cases in Italy, originating in various endemic areas throughout the world [ATPase6] (Mus musculus) PubMed

 4718.

complex interplay of domain-domain communication & nonactive-site modulation of catalysis in P. falciparum TS-DHFR. parasitic TS-DHFR is activated by mechanisms, modulated by their nonactive site regions[thymidylate synthase-dihydrofolate reductase] (Mus musculus) PubMed

 4719.

These results suggest that secreted PfHMGB1 (high mobility group box protein 1) and PfHMGB2 may be responsible for eliciting/ triggering host inflammatory immune responses associated with malaria infection. [HMGB1, HMBG2] (Mus musculus) PubMed

 4720.

The active conformation of protein kinase 7 is stabilized by a structural motif in which the role of the conserved phosphorylated residue that assists in structuring the activation loop is played by an arginine residue (protein kinase 7). (Mus musculus) PubMed

 4721.

wild-type histoaspartic protease (HAP), H34A and S37A were strongly inhibited by the serine protease inhibitor phenylmethanesulfonyl fluoride[histoaspartic protease] (Mus musculus) PubMed

 4722.

Native data sets extending to 1.9 A resolution have been collected and phasing is under way[var2csa and EMP1] (Mus musculus) PubMed

 4723.

show the production of a properly folded Pfs48/45 C-terminal fragment by simultaneous coexpression with four periplasmic folding catalysts in Escherichia coli[Pfs48/45] (Mus musculus) PubMed

 4724.

These results indicate a role of TRAP-Like Protein (TLP) in cell traversal by sporozoites [TLP]. (Mus musculus) PubMed

 4725.

Pfdpm1 represents a unique enzyme among subgroups compared in this study.(Pfdpm1) (Mus musculus) PubMed

 4726.

findings show that PfATP6 is a more diverse gene than previously demonstrated [ATP6] (Mus musculus) PubMed

 4727.

VAR2CSA appears to be a major ligand for placental adhesion.[var2csa] (Mus musculus) PubMed

 4728.

strong association between pfcrt , but not pfmdr1 86Y mutation and in vivo chloroquine resistance [pfcrt] (Mus musculus) PubMed

 4729.

Binding of TRAP to SH3-domain containing proteins like Src-family kinases and their ability to phosphorylate PfTRAP suggests a novel role for TRAP in cell signaling during sporozoite invasion and homing inside the liver cells. [Trap] (Mus musculus) PubMed

 4730.

MSP2 associates with lipid micelles, but predominantly through the N-terminal region rather than the C terminus, which is GPI-anchored to the membrane in the parasite. (Mus musculus) PubMed

 4731.

These data demonstrate a role for central memory T cells in natural malarial immunity and support current vaccination strategies aimed at inducing durable protective T cell responses against the TRAP antigen.[TRAP] (Mus musculus) PubMed

 4732.

Compared with the human enzyme, the recombinant P. falciparum thymidylate kinase showed a broader spectrum of substrate specificity (thymidylate kinase). (Mus musculus) PubMed

 4733.

Collectively, these findings point towards an essential role for the PfTSN in the parasite's infection cycle.[Plasmodium falciparum Tudor Staphylococcal Nuclease (PfTSN)] (Mus musculus) PubMed

 4734.

Plasmodium telomeres might fold back and that Orc1 cooperates with Sir2 in telomeric silencing [Orc1] (Mus musculus) PubMed

 4735.

The experiments did not reveal significant changes in var2CSA levels and chondroitin sulfate A-binding capacity.[var2CSA in strain 193CSA] (Mus musculus) PubMed

 4736.

The bacterial histone-like protein exhibits DNA binding and is capable of condensing DNA (bacterial histone-like protein). (Mus musculus) PubMed

 4737.

a limited genetic polymorphism of the P126 OR domain does not seem to influence the development of a specific humoral immune response to P126 [P126 antigen (Sera or SERP)] (Mus musculus) PubMed

 4738.

New insight into Plasmodium falciparum chloroquine resistance transporter {PFCRT) function and, along with previous results, proposing a model for a single chloroquine binding site. (Mus musculus) PubMed

 4739.

Lack of MSP7 was not lethal at the asexual blood stage, but it impair the invasion of erythrocytes by merozoites. [MSP7] (Mus musculus) PubMed

 4740.

Genetic analyses of Reticulocyte Binding protein PfRh2b reveal that the entire cytoplasmic tail and the conserved motif within the cytoplasmic tail are indispensable for invasion Plasmodium falciparum. (Mus musculus) PubMed

 4741.

Pf332 both modulates the level of increased red blood cell(RBCs) rigidity induced by Plasmodium falciparum and plays a significant role in adhesion by assisting transport of PfEMP1 to the infected RBC surface[ Pf332 ] (Mus musculus) PubMed

 4742.

We heterologously coexpressed AK2 and P. falciparum N-myristoyltransferase (NMT) in the presence of myristate in Escherichia (Mus musculus) PubMed

 4743.

Reverse genetics in the rodent malaria model, Plasmodium berghei, suggests that profilin is essential for the invasive blood stages of the parasite. [profilin] (Mus musculus) PubMed

 4744.

The Pf332 DBL domain conformed to the generic pattern for DBL domains. Pf332 is not involved in cytoadhesion or merozoite invasion. [Pf332] (Mus musculus) PubMed

 4745.

The occurrence of mutations was investigated in the pfmdr1 (N86Y) and pfcrt (K76T) genes, associated with CQ resistance, as well as in pfdhfr (C59R), pfdhps (K540E), conferring sulphadoxine-pyrimethamine resistance. (pfmdr1)(pfcrt)(pfdhfr)(pfdhps) (Mus musculus) PubMed

 4746.

There was a correlation only between Pfs 16 cDNA overexpression in the first 48h of the culture and the production of mature gametocytes. Pfs 16 is an early marker of the development of mature gametocytes in cultures [Pfs16] (Mus musculus) PubMed

 4747.

high-resolution atomic force microscopy revealed non-linear asymmetric structures, with beaded domains and flexible loops that were recognized predominantly as dimers, although monomers and larger multimers were observed[MSP3, FVO strain] (Mus musculus) PubMed

 4748.

spatial orientation of domains of the heat shock protein 70 from Plasmodium falciparum and the protein's chaperone function (Mus musculus) PubMed

 4749.

Stx1 is the first identified vesicular trafficking component localized proximal to the P. falciparum plasma membrane.[Stx1] (Mus musculus) PubMed

 4750.

Parasites with the PfRh2b deletion were found to preferentially utilize protease-resistant pathways for erythrocyte invasion[PfRh2b, new isolate] (Mus musculus) PubMed

 4751.

Kinase activity was markedly affected by introducing a larger lysine residue instead of A111 and the lack of a hydroxyl group after inducing mutation of Y107F affected enzyme activity [TMP kinase, strain not indicated] (Mus musculus) PubMed

 4752.

Parasite recrudescences in 33 consecutive paired episodes during the same pregnancy were identified by msp1 and msp2 [msp1,msp2] (Mus musculus) PubMed

 4753.

sequenced the complete HDP gene encompassing three exons and two introns from five P. falciparum lab strains with known CQ sensitivity and 50 field isolates from Venezuela and Kenya, with high levels of CQ resistance [heme detoxification protein] (Mus musculus) PubMed

 4754.

The presence of three or more copies of pfmdr1 were associated with recrudescence in artesunate-mefloquine treated patients [Pfmdr1] (Mus musculus) PubMed

 4755.

results suggest that saglin/TRAP interaction is crucial for salivary gland invasion by Plasmodium sporozoites [TRAP] (Mus musculus) PubMed

 4756.

MAHRP-1 specifically interacts with erythrocyte membrane through a 20-mer-long amino acid region, raising questions about this region's potential as a therapeutic target against malaria.(MAHRP-1) (Mus musculus) PubMed

 4757.

The N-terminus but not the C-terminus of REX2 is important for export. A single-point mutation in the N-terminus abolishes export. [REX2] (Mus musculus) PubMed

 4758.

PfNapL has unique histone binding properties [PfNapL] (Mus musculus) PubMed

 4759.

The P. falciparum PfATPase gene is polymorphic at the 569 codon (Mus musculus) PubMed

 4760.

first report implicating an heterochromatin protein 1 protein in the control of antigenic variation of a protozoan parasite (heterochromatin protein 1). (Mus musculus) PubMed

 4761.

The presented results demonstrate that reduction in the mobility of this region in Pdx1 proteins is required for formation of the in vivo dodecamer, negatively affecting the activity of Pdx1, opening the possibility of allosteric Pdx1 inhibitors.[Pdx1] (Mus musculus) PubMed

 4762.

Nhe-1 polymorphism was significantly associated with reduced quinine susceptibility. [Nhe-1] (Mus musculus) PubMed

 4763.

In the apoenzyme crystals, HAP forms a tight dimer not seen previously in any aspartic protease.[HAP] (Mus musculus) PubMed

 4764.

These findings indicate that genetically CQ-resistant P. falciparum are more common than previously thought in Madagascar even though the fitness of the minority variant pfcrt 76T parasites remains unclear (Mus musculus) PubMed

 4765.

reports variation in C-terminal region of MSP-1 from P falciparum isolates from southern Iran [MSP-1] (Mus musculus) PubMed

 4766.

analysis of the interactions of curcumin with PfATP6 (Mus musculus) PubMed

 4767.

present work represents the first evidence for functional interactions between the PfHsp70-1 and Pfj1 [Hsp70-1] (Mus musculus) PubMed

 4768.

The isolation and characterization of protein arginine N-methyltransferase 1 (PRMT1) in Plasmodium falciparum is reported.[PRMT1] (Mus musculus) PubMed

 4769.

A study on the metal ion binding characteristics of recombinant P. falciparum M17 leucine aminopeptidase (rPfLAP) shows that the active site of this exopeptidase contains two metal-binding sites. (Mus musculus) PubMed

 4770.

pfnhe contributes to QN resistance[sodium-proton exchanger PfNHE] (Mus musculus) PubMed

 4771.

the 40 residue C-terminal domain of MSP3 protein self-assembles into a four-stranded alpha-helical coiled coil structure where alpha-helices are packed "side-by-side" [no strain specified; merozoite surface protein 3] (Mus musculus) PubMed

 4772.

Evidence is provided that one of the novel eIF2alpha kinases, PfeIK1, is able to phosphorylate the P. falciparum eIF2alpha orthologue in vitro [PfeIK1 and eIF2alpha] (Mus musculus) PubMed

 4773.

study reports structure of the gene that encodes PfRON4 & its apparent limited diversity amongst geographically diverse P. falciparum isolates; also report that PfRON4 protein sequences elicit immunogenic responses in natural malaria infections[PfRON4] (Mus musculus) PubMed

 4774.

A structural model of pro-falcipain-2 was constructed by homology modeling based on crystallographic structures of mature falcipain-2, procathepsin K, procathepsin L, and procaricain.[Falcipain-2] (Mus musculus) PubMed

 4775.

A functional nek-2 gene is required for transmission of both Plasmodium falciparum and the rodent malaria parasite Plasmodium berghei to the mosquito vector.[Nek-2] (Mus musculus) PubMed

 4776.

monomerdimer interconversion of ferredoxin-NADP+ reductase can be controlled by oxidizing and reducing agents that are possibly present within the apicoplast, such as H(2)O(2), glutathione, and lipoate.[ferredoxin--NADP reductase] (Mus musculus) PubMed

 4777.

Immunofluorescence studies with antibodies to functional ferrochelatase reveal that the native enzyme is localized to the mitochondrion of the parasite indicating that this organelle is the ultimate site of heme synthesis.[ferrochelatase] (Mus musculus) PubMed

 4778.

Despite vast diversity, restricted disease-associated var genes were identified and might be used for innovative interventions based on erythrocyte membrane protein-1.[EMP1] (Mus musculus) PubMed

 4779.

These findings suggest that the two arginine residues surrounding T121 are critical for the binding specificity of BAEBL (VSTK) to sialic acid and suggest a role for arginine in sialic acid binding independent of its negative charge.[BAEBL] (Mus musculus) PubMed

 4780.

Kinetic data in combination with expression result support the proposal of serine hydroxymethyltransferase reaction being a regulatory step for dTMP cycle.[serine hydroxymethyltransferase] (Mus musculus) PubMed

 4781.

potential in vivo regulation of Pfnek3, with residues T82, S221 and S226 functioning as phospho-activating sites.[Pfnek3] (Mus musculus) PubMed

 4782.

Substrate of glyoxalase II is predominantly bound via ionic interactions with the conserved residues Arg(257) and Lys(260), and that correct substrate binding is a pH- and salt-dependent rate-limiting step for catalysis. [glyoxalase II] (Mus musculus) PubMed

 4783.

The above observations suggest that the antibody response against RAP-2/RSP-2 and other members of the complex could trigger the destruction of RAP-2/RSP-2-tagged host cells.[RAP2] (Mus musculus) PubMed

 4784.

DBL6 epsilon domain of VAR2CSA binds to placental chondroitin sulfate proteoglycans through a positively charged surface on the distal side of subdomain 2 that is exposed in intact VAR2CSA on the erythrocyte surface.[VAR2CSA] (Mus musculus) PubMed

 4785.

The immune reaction of adults and children to liver stage antigen 1 (LSA-1) and thrombospondin-related adhesive protein (TRAP) among adults and children are reported.[LSA-1; TRAP] (Mus musculus) PubMed

 4786.

1 amino acid substitution was responsible not only for PyEBL localization but also the erythrocyte-type invasion preference of the parasite and subsequently its virulence in mice[erythrocyte ligand or EBL] (Mus musculus) PubMed

 4787.

The distribution of TaSE during mitosis makes it a protein to consider as playing a potential role for parasite distribution into daughter host cells. [TaSE] (Mus musculus) PubMed

 4788.

These experiments suggest that ACE1 appressorium-specific expression does not depend on host plant signals but is connected to the onset of appressorium-mediated penetration. [ACE1 protein] (Mus musculus) PubMed

 4789.

These data indicate that the MAPK-docking site of Mst7 is essential for its association and activation of downstream Pmk1, and the Mst7-Pmk1 interaction is enhanced or stabilized during appressorium formation. [Mst7, Pmk1] (Mus musculus) PubMed

 4790.

Rgs1 regulates multiple Galpha subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism. [Rgs1] (Mus musculus) PubMed

 4791.

These observations suggest that Con7p encodes a transcription factor required for the transcription of several genes which participate in disease-related morphogenesis in M. grisea.[Con7p] (Mus musculus) PubMed

 4792.

Results describe the involvement of a Magnaporthe grisea serine/threonine kinase gene, MgATG1, in appressorium turgor and pathogenesis [Atg1]. (Mus musculus) PubMed

 4793.

MIR1 is an M. grisea-specific gene that is highly conserved among the field isolates belonging to the M. grisea species complex; mir1 mutants had no obvious defects in appressorial penetration and rice infection. [Mir1 gene] (Mus musculus) PubMed

 4794.

The snodprot1 homolog MSP1 is required for virulence. (Mus musculus) PubMed

 4795.

Two superoxide-generating NADPH oxidase-encoding genes, Nox1 and Nox2, are independently required for pathogenicity of M. grisea. [Nox1 & Nox2 NADPH oxidase] (Mus musculus) PubMed

 4796.

Cut2 is therefore required for surface sensing leading to correct germling differentiation, penetration, and full virulence in this model fungus.[Cutinase2] (Mus musculus) PubMed

 4797.

The data suggests that ABC4 is required for the pathogenicity of M. grisea, helping the fungus to cope with the cytotoxic environment during infection.[ABC4] (Mus musculus) PubMed

 4798.

EGL1 endoglucanase from Magnaporthe grisea was characterized [EGL1] (Mus musculus) PubMed

 4799.

The mig1 deletion mutant had a normal growth rate and formed melanized appressoria, but it was nonpathogenic and failed to infect rice leaves through wounds.[mig1] (Mus musculus) PubMed

 4800.

[ACE1] The avirulence gene ACE1 from the rice blast fungus Magnaporthe grisea encodes a polyketide synthase (PKS) fused to a nonribosomal peptide synthetase (NRPS). (Mus musculus) PubMed

 4801.

The results demonstrate that MgLig4 is involved in, but not essential for, the non-homologous end-joining system.[MGLIG4 in strain Guy11] (Mus musculus) PubMed

 4802.

study focuses on expression analysis, recombinant production and biochemical characterization of intracellular catalase/peroxidase of M. grisea (MagKatG1); [MagKatG1] (Mus musculus) PubMed

 4803.

interactions between Rac1 and PAK kinase Chm1 are responsible for conidiogenesis, and between Rac1 and NADPH oxidases Nox1 and Nox2 are important for pathogenicity [Rac1][Chm1] (Mus musculus) PubMed

 4804.

PMK1 gene sequence is homologous to MAPK gene. So are their functions. (Mus musculus) PubMed

 4805.

The authors conclude that MgCRZ1 is essential for growth, development, and full virulence of Magnaporthe grisea.[CRZ1] (Mus musculus) PubMed

 4806.

Mstu1 is required for appressorium-mediated infection due to its involvement in the mobilization of lipids and glycogen.[Mstu1] (Mus musculus) PubMed

 4807.

CaM targets to the germ tubes, conidia, mycelia and the least in the aerial hypha. [CaM] (Mus musculus) PubMed

 4808.

Plays an important role in the autolytic process in A. nidulans. (chiB; class V chitinase) (Mus musculus) PubMed

 4809.

Study shows that ASTA is a physiological sulfate transporter; and reports cloning and characterization of the sulfate permease, sB gene; both genes, sB and astA, are regulated at the transcriptional level by sulfur metabolite repression [sB, astA] (Mus musculus) PubMed

 4810.

results expand the number of known and predicted secondary metabolites requiring CfwA/NpgA for their biosynthesis, and suggest that a single PPTase is responsible for the activation of all PKSs and NRPSs in A. nidulans [CfwA/NpgA] (Mus musculus) PubMed

 4811.

The Aspergillus nidulans Sur2 homolog BasA is also required for phytosphingosine biosynthesis but is also essential for viability.[BasA protein] (Mus musculus) PubMed

 4812.

Results describe the processing of MYC(3)-tagged PacC in Western blots, and show unequivocally that PalB is essential for signaling proteolysis and is definitely not the processing protease [PacC, PalB]. (Mus musculus) PubMed

 4813.

effect of substitution of R17 by N17 in PinA has been investigated by computational study, predicted that changing R17 to N17 in PinA lowers the ligand binding affinity as a result of reduced H-bonding between protein & phosphate group of ligand.[PinA] (Mus musculus) PubMed

 4814.

The bZIP transcription factor MeaB was found to activate nmrA expression and a conserved element, TTGCACCAT, bound by MeaB in vitro is present in the promoters of NmrA homologues in other filamentous ascomycetes [NmrA and MeaB] (Mus musculus) PubMed

 4815.

The results indicate an important role of the pentose phosphate pathway in the fungal proliferation during endogenous DNA damage and polar growth monitored by the AtmA kinase.[AtmA] (Mus musculus) PubMed

 4816.

Data show that mitotic cytosolic localization of NapB might facilitate its putative role in the sorting of protein cargoes to the vacuole and that NapB and the mitotic B-type cyclin NimE compete for in vitro binding to KapA. [NapB KapA] (Mus musculus) PubMed

 4817.

VosA couples sporogenesis and trehalose biogenesis in Aspergillus nidulans [VosA] (Mus musculus) PubMed

 4818.

a gene containing the esd0543 EST, named esdC, was isolated and characterized; the gene structure, the expression pattern during development, and the function of the gene in development were investigated [escD] (Mus musculus) PubMed

 4819.

CopA:GFP localized to putative Golgi equivalents that were concentrated at hyphal tips. [CopA] (Mus musculus) PubMed

 4820.

Results indicate that pkcA plays an important role in the maintenance of cell integrity (pkcA). (Mus musculus) PubMed

 4821.

The identification of two cell end marker proteins, TeaA and TeaR, in Aspergillus nidulans, is described.[TeaA, TeaR] (Mus musculus) PubMed

 4822.

Data describe overexpression and characterization of TdiB, which catalyzes the reverse prenylation event during terrequinone A biosynthesis [TdiB] (Mus musculus) PubMed

 4823.

The sumO gene was deleted in a diploid and sumODelta haploids were recovered. The mutant was viable but exhibited impaired growth, reduced conidiation and self-sterility.[sumO in strain A234] (Mus musculus) PubMed

 4824.

Histone H3 acetylation is not required for transcriptional activation and chromatin remodeling but is required for the repression of prnB and prnD and for the repositioning of nucleosomes in the divergent promoter region.[Histone H3; prnD; prnB] (Mus musculus) PubMed

 4825.

Study purified of CoA-transferase from A. nidulans and characterized its biochemical properties; enzyme used succinyl-, propionyl- and acetyl-CoA as CoASH donors and the corresponding acids as acceptor molecules.[CoA transferase] (Mus musculus) PubMed

 4826.

In actively growing hyphae, cortical ActA::GFP and FimA::GFP patches were highly mobile throughout the hypha and were concentrated near hyphal apices.[ActA or AN6542.3, FimA or AN5803.3] (Mus musculus) PubMed

 4827.

Study isolated the NUDF-associated protein BNFA (for binding to NUDF); BNFA was dispensable for growth and for nuclear migration; GFP-BNFA fusions localized to SPBs at different stages of the cell cycle.[BNFA] (Mus musculus) PubMed

 4828.

The eglD gene is constitutively expressed in all developmental stages and compartments of A. nidulans asexual life cycle. [eglD] (Mus musculus) PubMed

 4829.

CreA and XlnR form a transcriptional cascade regulating A. nidulans xylanolytic genes.[CreA and XlnR] (Mus musculus) PubMed

 4830.

These results suggest that ChiA functions as a GPI-anchored chitinase at the sites where cell wall remodeling and/or cell wall maturation actively take place. [ChiA] (Mus musculus) PubMed

 4831.

UvsF is essential for DNA replication.[UvsF] (Mus musculus) PubMed

 4832.

All three MCN proteins likely have cell cycle functions. [MCNA, MCNB, and MCNC] (Mus musculus) PubMed

 4833.

Data show that the Aspergillus nidulans kinesin-3 motor protein UncA transports vesicles along a subpopulation of microtubules and is required for fast hyphal extension. (Mus musculus) PubMed

 4834.

subcellular localization studies of GFP-fused AmyR in A. nidulans [AmyR] (Mus musculus) PubMed

 4835.

Aspergillus nidulans Mlp1 nuclear pore complex protein has previously unrealized mitotic roles involving spatial regulation of spindle assembly checkpoint (SAC) proteins.[Mlp1] (Mus musculus) PubMed

 4836.

KapA is required for the completion of both sexual and asexual reproductive cycles. [KapA] (Mus musculus) PubMed

 4837.

Deletion mutant strains also accumulated more carbonylated proteins when exposed to hydrogen peroxide indicating that MsrA and MsrB are active players in the protection of the cellular proteins from oxidative stress damage.[MsrA & MsrB] (Mus musculus) PubMed

 4838.

SNAD acted as a scaffold protein that is required for the localization of the septation initiation network proteins of SIDB and MOBA to the spindle pole body.[SNAD, MOBA, SIDB] (Mus musculus) PubMed

 4839.

Data show that overexpression of nsdC not only enhanced formation of cleistothecia but also overcame inhibitory effects of certain stresses on cleistothecial development, implying that NsdC is a key positive regulator of sexual development: [nsdC] (Mus musculus) PubMed

 4840.

PepJ is a deuterolysin-type metallo-proteinase. [PepJ] (Mus musculus) PubMed

 4841.

Myosin motor-like domain of CsmB is crucial for its proper localization via interaction with actin. [CsmB] (Mus musculus) PubMed

 4842.

Data show that A. nidulans pigP mutants have significantly decreased glycosylphosphatidylinositol synthesis [pigP] (Mus musculus) PubMed

 4843.

crucial involvement of the NikA histidine kinase-SskA/SrrA phosphorelay system in both osmotic adaptation and asexual development [NikA histidine kinase] (Mus musculus) PubMed

 4844.

The combined evidence points to FlbB as a key factor in the transition to asexual development, playing a role at various control points in which the process could be reversed.[FlbB] (Mus musculus) PubMed

 4845.

detailed comparison of the quinol:fumarate reductase enzymes from C. jejuni and H. pylori with that of W. succinogenes [QFR] (Mus musculus) PubMed

 4846.

in vitro characterization of PglC as a bacillosamine 1-phosphoryl transferase provides direct evidence for the early steps in the C. jejuni N-linked glycosylation pathway [PglC] (Mus musculus) PubMed

 4847.

analysis of PseG of pseudaminic acid biosynthesis [PseG] (Mus musculus) PubMed

 4848.

results showed that the point mutation was responsible, via a lack of binding of the CmeR repressor, for increased expression of the CmeABC efflux pump and consecutive multidrug resistance [CmeR] (Mus musculus) PubMed

 4849.

In C. jejuni, tet(O) was plasmid-encoded in 54 % of tetracycline-resistant isolates, whereas in C. coli, tet(O) appeared to be located on the chromosome.[tet(O)protein] (Mus musculus) PubMed

 4850.

Analyses of transformation frequencies and glycosylation statuses of N-glycosylated proteins indicated partial suppression of pglF by pseC.[ pglF, pseC] (Mus musculus) PubMed

 4851.

The crystal structure of CmeR to 2.2 A resolution, revealed a dimeric two-domain molecule with an entirely helical architecture similar to members of the TetR family of transcriptional regulators.[CmerR] (Mus musculus) PubMed

 4852.

beta 1,3-galactosyltransferase CgtB variants from the bacterium Campylobacter jejuni have distinct acceptor specificities [CgtB] (Mus musculus) PubMed

 4853.

The C. jejuni ppk1 mutant was also defective for the virulence-associated phenotype of intraepithelial cell survival in a tissue culture infection model and exhibited a striking, dose-dependent chick colonization defect [polyphosphate kinase 1] (Mus musculus) PubMed

 4854.

Strain 81-176 demonstrated GADH activity, converting d-gluconate to 2-keto-d-gluconate, that was higher at 42 degrees C than at 37 degrees C. In contrast, cj0414 and cj0415 mutants lacked GADH activity.[cj0414 and cj0415 in strain 81-176] (Mus musculus) PubMed

 4855.

The results demonstrate that cytolethal distendin toxin CDT(+) C. jejuni strains adhere to and invade epithelial cells more efficiently than CDT(-) strains. CDT is responsible for intestinal pathology and the colon is the major target. [DT] (Mus musculus) PubMed

 4856.

Diffraction data have been collected from these crystal forms to 2.5 and 2.95 A resolution, respectively[ stationary-phase survival E] (Mus musculus) PubMed

 4857.

Multifunctionality of Campylobacter jejuni sialyltransferase CstII. [CstII sialyltransferase] (Mus musculus) PubMed

 4858.

C. jejuni strains carrying a sialyltransferase gene (cst-II), which is essential for the biosynthesis of ganglioside-like lipooligosaccharides, are associated with the development of Guillain-Barre syndrome (Mus musculus) PubMed

 4859.

CetA has two transmembrane helices in a helical hairpin while CetB is a peripheral membrane protein tightly associated with the membrane. [CetA, CetB] (Mus musculus) PubMed

 4860.

Key residues in the binding site are essential for Cj0977 virulence function, suggesting a possible function of Cj0977 as an acyl-CoA binding regulatory protein.[Cj0977, sigma 28]] (Mus musculus) PubMed

 4861.

The maf4 mutant displayed strongly delayed bacterial autoagglutination. (Mus musculus) PubMed

 4862.

Report immunogenicity and immunoprotection of recombinant PEB1 in Campylobacter-jejuni-infected mice. (Mus musculus) PubMed

 4863.

The data indicate that Cj1279c is a novel adhesin. Because Cj1279c harbors fibronectin type III domains, the authors designated the protein FlpA, for fibronectin-like protein A.[FlpA] (Mus musculus) PubMed

 4864.

We have investigated a novel AA-ABC transporter system, encoded by cj0467 to cj0469 which led us to designate these genes (paqP and paqQ) (Mus musculus) PubMed

 4865.

Amino acid substitution mutagenesis demonstrated that R327, a basic amino acid that is highly conserved in CfrA, plays a critical role in ferric enterobactin acquisition in Campylobacter jejuni.[CfrA] (Mus musculus) PubMed

 4866.

The crystal structure of the GT family 42 Campylobacter jejuni alpha-2,3/2,8-sialyltransferase (CstII) provides key insights into the sialyl-transfer mechanism, including tentative identification of His188 as the catalytic base [CstII] (Mus musculus) PubMed

 4867.

Data conclude that FlpA mediates C. jejuni attachment to host epithelial cells via fibronectin binding. (Mus musculus) PubMed

 4868.

the lack of PspC significantly enhances the susceptibility of S. pneumoniae to both bactericidal activity and secretory response by the microglial cells.[PspC] (Mus musculus) PubMed

 4869.

data suggest that potD is involved in pneumococcal polyamine transport and is important for pathogenesis within various infection models [potD] (Mus musculus) PubMed

 4870.

adr as the structural gene of the pneumococcal peptidoglycan O-acetylase was identified. (adr) (Mus musculus) PubMed

 4871.

Surface expression of PspC was analysed in pneumococcal isolates of different pathological sources. [PspC] (Mus musculus) PubMed

 4872.

structure-function studies of previously uncharacterized glycogen-binding modules in the surface-anchored pullulanase SpuA; multivalent binding to glycogen leads to a strong interaction with alveolar type II cells in mouse lung tissue [SpuA] (Mus musculus) PubMed

 4873.

Ply, PspA, and PspC expression resulted in C3 degradation in vitro and in vivo.[Ply, PspA, PspC] (Mus musculus) PubMed

 4874.

of 174 S. pneumoniae isolates, 76 (44%) had alterations in all of the three genes examined (pbp1a, pbp2b, and pbp2x), 81 (47%) had alterations in one or two of the genes, and 17 (10%) had no alterations [pbp1a, pbp2b, pbp2x] (Mus musculus) PubMed

 4875.

In tetracycline-susceptible pneumococci with erm(B)-mediated erythromycin resistance, the erm(B) gene is carried on a variety of Tn916-related genetic elements either lacking tet(M) or, more often, carrying an unexpressed tet(M) gene. [ErmB] (Mus musculus) PubMed

 4876.

While various adherence mechanisms have been characterized for pneumococci, the specific interaction of PspC with complement factor H represents a novel mechanism that tethers pneumococci to host tissues.[PspC protein] (Mus musculus) PubMed

 4877.

characteristics of four optochin-resistant (Opt(r)) Streptococcus pneumoniae isolates from Brazil; all four Opt(r) isolates presented mutations in the nucleotide sequence coding for the c subunit of F(0)F(1) ATPase [atpC] (Mus musculus) PubMed

 4878.

We conclude that a suicide gene of pneumococcus is spxB, which induces an apoptosis-like death in pneumococci and confers a selective advantage in nasopharyngeal cocolonization. [SpxB] (Mus musculus) PubMed

 4879.

Upstream of czcD a gene was identified, encoding a novel TetR family regulator, SczA, that is responsible for the metal ion-dependent activation of czcD expression.[SczA, czcD] (Mus musculus) PubMed

 4880.

CpsA expression under ambient oxygen concentrations correlates with serotype-specific invasiveness and is inversely associated with the prevalence of serotype-specific carriage.[cpsA] (Mus musculus) PubMed

 4881.

rRNA structures that are required for efficient methylation by RlmA(II) [RlmA] (Mus musculus) PubMed

 4882.

examined susceptibility to erythromycin and distribution of macrolide-resistance genes, mefA and ermB in S. pneumoniae isolates from upper respiratory tracts of children in 4 cities in the Sapporo district, Hokkaido prefecture, Japan [mefA and ermB] (Mus musculus) PubMed

 4883.

The effects of multiple antibiotics on pneumolysin synthesis in Streptococcus pneumoniae were compared.[pneumolysin] (Mus musculus) PubMed

 4884.

Data suggest that RrgA is central in pilus-mediated adherence and disease, even in the absence of polymeric pilus production [RrgA] (Mus musculus) PubMed

 4885.

pneumolysin may be a particularly potent pneumococcal virulence factor in the setting of cirrhosis.[Pneumolysin from ATCC6303 strain] (Mus musculus) PubMed

 4886.

Telithromycin resistance is shown to be conferred by a deletion in erm(B) gene that increases rRNA methylation. [erm(B)] (Mus musculus) PubMed

 4887.

These data strongly suggest that Sp0928 encodes the S. pneumoniae type II signal peptidase (Lsp).[Sp0928 in strain 0100993] (Mus musculus) PubMed

 4888.

Variable penicillin resistance determinants were found in PBP 2x, PBP 2b, and PBP 1a in isolates of two Streptococcus pneumoniae clonal groups, Poland 23F-16 and Poland 6B-20. [PBP2x, PBP 2b, PBP1a] (Mus musculus) PubMed

 4889.

study analyzed in vitro and in vivo properties of penicillin-binding protein 2x (PBP2x )variants from cefotaxime-resistant laboratory mutants and a clinical isolate[PBP2x] (Mus musculus) PubMed

 4890.

In erm(B)-positive tetracycline-resistant pneumococci, Tn6003 was the least common erm(B)-carrying Tn916-related element and Tn6002 the most common. [ermB] (Mus musculus) PubMed

 4891.

Results describe the structure, ligand recognition and mechanism of sulfonamide resistance of dihydropteroate synthase (DHPS) from Streptococcus pneumoniae [DHPS]. (Mus musculus) PubMed

 4892.

A young mouse model is established for complicated pneumococcal pneumonia. This model proved that allelic variation of zmpB affects the virulence of S. pneumoniae.[zmpB] (Mus musculus) PubMed

 4893.

We demonstrated that 2 genetic loci, SP_2170 (AdcB, zinc ABC transporter) and SP_0157 (hypothetical protein), were involved in adherence to A549 cells.[SP_2170 and SP_0157 in strain 820047] (Mus musculus) PubMed

 4894.

It was determined that the pilus locus is down-regulated by preexisting networks designed for adhesion and cation transport/response and that its regulation occurs through RlrA. [RlrA] (Mus musculus) PubMed

 4895.

Transcription of dnaK and groEL operons in Streptococcus pneumoniae in regulated by HrcA and calcium. (Mus musculus) PubMed

 4896.

Sequence analysis revealed that most penicillin-nonsusceptible S. pneumoniae isolates (penicillin MIC > or = 1.5 microg/mL and cefotaxime MIC > or = 2 microg/mL) shared identical PBP2b, PBP2x, and PBP1a amino acid profiles.[PBP2b, PBP2x, PBP1a] (Mus musculus) PubMed

 4897.

The structure of a neuraminidase from S. pneumoniae: the crystal structure of NanB in complex with its reaction product 2,7-anhydro-Neu5Ac is reported. (Mus musculus) PubMed

 4898.

Expression of psaA, pspC and cbpG is differentially regulated. [psaA, pspC and cbpG] (Mus musculus) PubMed

 4899.

The purpose of this work was to characterize guanylate kinases from both gram positive and gram negative pathogenic bacteria. (Mus musculus) PubMed

 4900.

PfbA is a novel plasmin- and fibronectin-binding protein of Streptococcus pneumoniae and an important factor in the development of pneumococcal infections (Mus musculus) PubMed

 4901.

The 2 component regulatory system CiaRH is involved in regulation of pneumocin via upregulation of HtrA, a serine protease, production. [CiaR, CiaH, HtrA] (Mus musculus) PubMed

 4902.

analysis of structure and mechanism of Streptococcus pneumoniae endohexosaminidase D [Endo-D] (Mus musculus) PubMed

 4903.

the authors show that degradation of model SsrA-tagged proteins in Streptococcus pneumoniae depends primarily or exclusively on ClpXP in vivo.[ClpXP] (Mus musculus) PubMed

 4904.

certain S. pneumoniae strains transport and potentially metabolize the histo-blood group antigen carbohydrates of its host (Mus musculus) PubMed

 4905.

PspA-capsular polysaccharides conjugate vaccine produced strong protection to mice against the invasion of 1, 5, 6B, 19F, 23F serotypes. (Mus musculus) PubMed

 4906.

These data demonstrate a previously unsuspected role for branched-chain amino acid transport during infection for S. pneumoniae. [LivJHMGF] (Mus musculus) PubMed

 4907.

identified a new allelic variant of PspC (PspC4.4) as a major ligand for complement inhibitor C4b-binding protein [PspC] (Mus musculus) PubMed

 4908.

Xray structure to to 1.7 A resolution[DesR] (Mus musculus) PubMed

 4909.

Here, we show that LytR, a pneumococcal protein from the LytR-CpsA-Psr family, is essential for normal septum formation in cell division. [LytR] (Mus musculus) PubMed

 4910.

These findings demonstrate that S. pneumoniae phages use the ubiquitous host autolysin, LytA, to accomplish an optimal phage exiting strategy.[LytA] (Mus musculus) PubMed

 4911.

Taken together, these data suggest that EstA of Streptococcus pneumoniae is a novel inducer of NO and pro-inflammatory cytokines by activating the NF-kappaB, p38 and ERK 1/2 MAPK pathways during inflammatory responses.[EstA] (Mus musculus) PubMed

 4912.

Results present the structure of Wzb in complex with phosphate and high-resolution structures of apo-CpsB and a phosphate-complexed CpsB [CpsB] (Mus musculus) PubMed

 4913.

SpxA1 is a negative transcriptional regulator of X-state development. [Spx1] (Mus musculus) PubMed

 4914.

role of the interaction of DivIB with FtsL and DivIC proteins [DivIB,FtsL,DivIC] (Mus musculus) PubMed

 4915.

clpE gene-deficient Streptococcus pneumoniae expresses fewer kinds of proteins at also lower levels than the wt bacteria, suggesting that ClpE allows the bacteria to adapt to different host environments by inducing the expression of special proteins[clpE] (Mus musculus) PubMed

 4916.

Solving two crystal structures for SrtC suggests that an opening of a flexible lid and a concomitant cysteine rotation are important for catalysis and the activation of the catalytic cysteine of pilus-associated sortases.[Sortase C] (Mus musculus) PubMed

 4917.

Genetic dependencies of patch formation suggest that patch formation involves cross talk between Myo1p and Wsp1p/Vrp1p pathways.[Myo1, vrp1, wsp1] (Mus musculus) PubMed

 4918.

analysis uncovers an important role for Grn1p/GNL3L within this unique group of nucleolar GTPases (Mus musculus) PubMed

 4919.

Moc3 (SPAC821.07c) was a novel protein containing a Zn-finger (Zn(2)-Cys(6)) motif. Thus, Moc3 is not only involved in sexual development, but also in ascus formation and DNA integrity in an independent manner with Moc1 and Moc2 in S. pombe. (Mus musculus) PubMed

 4920.

characterizeation of Pmo25p; it is required to maintain polarized growth in interphase and is involved in cell separation following cytokinesis it's an essential protein required for polar growth [Pmo25p] (Mus musculus) PubMed

 4921.

Dcp1p binding to Dcp2p may regulate Dcp2p activity through conformational changes of the two domains [Dcp2p] (Mus musculus) PubMed

 4922.

Genetic epistasis studies and whole genome expression profiling show that Cip1 and Cip2 exert posttranscriptional control of gene expression in a manner that is counteracted by Csx1. [cip1, cip2, csx1] (Mus musculus) PubMed

 4923.

Mok12p, Mok13p, Mok14p are required for sporulation to succeed [Mok12p, Mok13p, Mok14p] (Mus musculus) PubMed

 4924.

a novel DNA repair heterodimer of Nse5 and Nse6, which are nonessential nuclear proteins critical for chromosome segregation in fission yeast [NSE5, NSE6] (Mus musculus) PubMed

 4925.

Mia1p is a microtubule-binding protein that preferentially localized to the minus ends of microtubules and is associated with the sites of microtubule attachment to the nuclear envelope. (Mus musculus) PubMed

 4926.

Up-regulation of the S. pombe thioredoxin reductase TrxR gene is mediated by Pap1 via the transcriptional motif( s) located on the -499 approximately -186 bp region. [TxR][Pap1] (Mus musculus) PubMed

 4927.

Swe1 prevents Clb2-Cdk1-mediated mitotic activities, but has little effects on Clb5-Cdk1-associated S-phase progression. (Swe1) (Mus musculus) PubMed

 4928.

RecQ helicase Rqh1 reacts with homologous recombinant proteins in the repair of a double strand break created at a unique site within the Schizosaccharomyces pombe genome. (Mus musculus) PubMed

 4929.

a possible contribution of MR1 gene to the lethal process taking place in irradiated cells [MR1 gene] (Mus musculus) PubMed

 4930.

A complex including Bqt1 and Bqt2 is essential for connecting telomeres to the SPB (spindle-pole body - the centrosome equivalent in fungi). [bqt1, bqt2] (Mus musculus) PubMed

 4931.

These results indicate that the vps26(+), vps29(+) and vps35(+) gene products are required for retrograde transport of SpVps10p from the prevacuolar compartment back to the Golgi in Sch. pombe cells.[vps26+, vps29+, vps35+] (Mus musculus) PubMed

 4932.

Num1p functions as a cortical-anchoring factor for dynein. Num1p is expressed in a meiosis-specific manner and localized to the cell cortex through its C-terminal PH domain (Mus musculus) PubMed

 4933.

The agn1 promoter contains three copies of the nucleotide sequence motif CCAGCC, whose presence seems to correlate with Ace2p-mediated transcription activation (agn1)(Ace2p). (Mus musculus) PubMed

 4934.

Telomere bouquet formation requires Bqt2p as a linking component and is finely regulated during meiotic progression. [Bqt2p] (Mus musculus) PubMed

 4935.

These results suggest a fundamental role for Ppc89 in organization of the S. pombe spindle-pole body (SPB). (Mus musculus) PubMed

 4936.

The functional mechanism of FMO from Schizosaccharomyces pombe using the crystal structures of the wild type and protein-cofactor and protein-substrate complexes was analyzed. (FMO) (Mus musculus) PubMed

 4937.

Eri1 controls the accumulation of heterochromatic siRNAs and negatively regulates the RNAi-mediated heterochromatin assembly. (Mus musculus) PubMed

 4938.

The two activities of La in tRNA maturation map to its two conserved RNA-binding surfaces (La protein). (Mus musculus) PubMed

 4939.

Map4p is a mating type-specific adhesin required for mating in h(+) cells and enhances cell adhesion when overexpressed. (Mus musculus) PubMed

 4940.

A functional analysis of spo5(+)(mug12(+)) of Schizosaccharomyces pombe, which encodes a putative RNA-binding protein, is reported here. (Mus musculus) PubMed

 4941.

The calcineurin-dependent response element (CDRE) in the promoter region of prz1(+) gene was identified and the calcineurin activity in living cells was monitored. (Mus musculus) PubMed

 4942.

results confirm that TrxR is a crucial determinant of the level of cellular ROS during oxidative stress as well as in the normal state[thioredoxin reductase] (Mus musculus) PubMed

 4943.

SWIRM1 and SWIRM2 are S pombe proteins with close homology to human histone H3 lysine 4 demethylase [SWIRM1, SWIRM2] (Mus musculus) PubMed

 4944.

These results suggest that Sld3 functions furthest upstream in initiation complex assembly, followed by GINS and Cut5, then Cdc45. Consistent with this conclusion, DDK but not cyclin-dependent kinase (CDK) was required for Sld3 loading.[Sld3, Cdc45, DDK] (Mus musculus) PubMed

 4945.

we show conclusively that the novel mitochondrial ADH is encoded by adh4 and, as such, is unrelated to ADH isoenzymes found in mitochondria of other yeasts.[adh4] (Mus musculus) PubMed

 4946.

A pof14 mutant lacking the F-box and an skp1-3 temperature sensitive mutant behave as wild type in the presence of oxidant showing that Pof14 function is independent of SCF. (Mus musculus) PubMed

 4947.

cyclin-dependent kinase 8 module forms a distinct structural entity that binds to the head and middle region of Mediator, thereby sterically blocking interactions with RNA polymerase II [cyclin-dependent kinase 8] (Mus musculus) PubMed

 4948.

These results suggest a close relationship between Cam2 and Myo1. In addition, both F-actin and Myo1 localized with Cam2 in the leading edge region [F-actin and Cam2]. (Mus musculus) PubMed

 4949.

The results indicate that the S. pombe pbh1 gene is up-regulated under metabolic oxidative stress in a Pap1-dependent manner. [Pbh1] (Mus musculus) PubMed

 4950.

results suggest that XPB/Ptr8p plays roles not only in nucleotide excision repair and transcription,but also plays a conserved role in mRNA export. (Mus musculus) PubMed

 4951.

Data suggest that Raf-1 may interfere with the role of Rad24 by competing with Rad24 for binding to Cdc25 or a direct phosphorylation of Cdc25, bypassing the checkpoint pathway in DNA repair through Cdc25 activation [Cdc25, Rad24]. (Mus musculus) PubMed

 4952.

DNA-replication stress appears to allow Caf1 to interact with Suc22, resulting in release of the nucleoplasmic Spd1-Suc22 assembly (Caf1 and Suc22). (Mus musculus) PubMed

 4953.

results show Sod22 has broad substrate specificity upon expression in S. cerevisiae & contributes to tolerance to high external levels of K(+); the S. pombe genome encodes 2 plasma membrane alkali metal cation/H(+) antiporters with different roles [Sod22] (Mus musculus) PubMed

 4954.

These findings demonstrate that PGRMC1 is required for P450 activity and suggest that interindividual variation in PGRMC1 function may impact multiple biochemical pathways and drug metabolism. (Mus musculus) PubMed

 4955.

crystal structures at 2.9 and 2.6 A resolution for ATP- and AMP-bound forms of a core alphabetagamma adenylate-binding domain from the fission yeast AMPK [AMPKalpha, beta, gamma] (Mus musculus) PubMed

 4956.

mus7(+) is involved in the repair of replication-associated DNA damage in the fission yeast Schizosaccharomyces pombe [mus7(+)] (Mus musculus) PubMed

 4957.

A second fission yeast Argonaute complex is identified which contains, in addition to Ago1, Arb1 and Arb2, both of which are required for histone H3 Lys9 (H3-K9) methylation, heterochromatin assembly and siRNA generation.[Arb1, Arb2] (Mus musculus) PubMed

 4958.

We propose that Agn2p (endo-(1,3)-alpha glucanase) participates in the endolysis of the ascus wall by hydrolysing its (1,3)-alpha-glucan, thereby assisting in the release of ascospores. [Agnp] (Mus musculus) PubMed

 4959.

Results suggest that during Rhp51-dependent repair of DSBs, Rqh1-Top3 suppresses crossovers in the Rhp57-dependent pathway while Mus81-Eme1 and possibly Rqh1 promote crossovers in the Swi5-dependent pathway [Mus81, Eme1]. (Mus musculus) PubMed

 4960.

Schizosaccharomyces pombe UGA1 (GABA aminotransferase) transaminates only gamma-aminobutyrate and not beta-alanine: UGA1 (Mus musculus) PubMed

 4961.

In addition to nuclear localization, a functional Cys-rich domain or nuclear export signal element in Cuf1 is required to appropriately regulate copper transport gene expression in response to changes in intracellular copper concentration.[Cuf1, Crm1] (Mus musculus) PubMed

 4962.

Dominant mutations in the Schizosaccharomyces pombe spindle pole body (SPB) component Cut12 enable cdc25.22 mutants to overcome a G2 arrest. [Cut 12.1 protein] (Mus musculus) PubMed

 4963.

Results suggest a crucial role for S. pombe Hop2-Mnd1 in homologous pairing and strand exchange by Dmc1 and Rad51 recombinases (Hop2 and Mnd1). (Mus musculus) PubMed

 4964.

a microtubule-associated protein, Alp7, which forms a complex with Alp14, is a target of Ran in yeast for spindle formation [Alp7, Ran] (Mus musculus) PubMed

 4965.

The Dds20 protein has functions in the Cds1-independent mechanism of UV damage tolerance of DNA.(Dds20) (Mus musculus) PubMed

 4966.

Overexpression of Jmj2 but not a catalytically inactive mutant reduced histone H3-Lysine-4 trimethylation levels in vivo and suppressed the toxicity caused by overexpression of the histone H3 lysine 4-binding protein [jmj2 protein] (Mus musculus) PubMed

 4967.

Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe [BHD] (Mus musculus) PubMed

 4968.

characterized the sterol signal for Sre1 activation (Sre1); the sterol-sensing domain of Scp1 is important for regulating Sre1 proteolysis (Scp1) (Mus musculus) PubMed

 4969.

Neither Fps1 nor Spo9 alone functions as a GGPS, but the two proteins together form a complex with GGPS activity.[Fps1, Spo9, GGPS] (Mus musculus) PubMed

 4970.

concerted actions of Spc1 and Lkh1 are required for the activation of Csx1 during oxidative condition in the fission yeast S. pombe[Csx1 and Lkh1] (Mus musculus) PubMed

 4971.

Electron microscopy studies were carried out to reveal the quaternary structure of the homo-octameric Pfk1 from S. pombe in the F6P-bound and in the ATP-bound state. (Mus musculus) PubMed

 4972.

potential relevance of Bin1-Ku interaction to cancer are discussed in light of these findings[pku80 and hob1] (Mus musculus) PubMed

 4973.

These findings suggest that cdc42p and bud6p activate for3p by relieving autoinhibition.[For3, cdc42, Bud6] (Mus musculus) PubMed

 4974.

Collectively, the results imply that Rad9 plays a protective role against nitrosative and nutritional stress and is positively regulated by NO and nitrogen starvation in a Pap1-dependent manner. [Rad9, Pap1] (Mus musculus) PubMed

 4975.

In this study, proteasome-COP9-initiation factor proteasome subunit, Rpn7, was isolated as a high copy suppressor that rescued the proteasome defects in yin6 null cells. (Mus musculus) PubMed

 4976.

Two related Schizosaccharomyces pombe proteins, Rfp1 and Rfp2, each having an N-terminal SUMO-interacting motif (SIM) and a C-terminal RING-finger domain, were identified.[Rpf1, Rpf2] (Mus musculus) PubMed

 4977.

propose a model for the regulation of the activity of the Spc1-stress-activated protein kinase signaling pathway by methylglyoxal in Schizosaccharomyces pombe[Spc1] (Mus musculus) PubMed

 4978.

Disruption of the sir2 gene in the superoxide dismutase deficient mutant enhanced the short chronological lifespan without more enhanced protein oxidation.(sir2)(sod) (Mus musculus) PubMed

 4979.

The tobacco (Nicotiana tabacum) day-neutral cv. Samsun transformed with the S. pombe mitotic activator gene cdc25 was used to study the onset of flowering.[cdc25] (Mus musculus) PubMed

 4980.

The conserved biochemical function of translin is not implicated in primary pathways for regulating genome stability and/or segregation.[Translin, TRAX] (Mus musculus) PubMed

 4981.

the ability of Pot1 to unfold the antiparallel tetraplex is required for telomerase-mediated telomere regulation. (Mus musculus) PubMed

 4982.

The results show that Bot1p has a novel function in the control of cell respiration by acting on the mitochondrial protein synthesis machinery. (Mus musculus) PubMed

 4983.

Expression of mag1 in the triple mutant confirmed the contribution of Mag1p and to base excision repair of methanesulfonate resistance. (Mus musculus) PubMed

 4984.

Pxl1p might cooperate with type II myosin and Rng2p-IQGAP to regulate actomyosin ring constriction as well as to maintain its integrity during constriction. (Pxl1p) (Mus musculus) PubMed

 4985.

The F-box & DNA helicase domains play indispensable but distinct roles in Fbh1 function. SCFFbh1 complex assembly is needed for the nuclear localization & DNA-damage-induced focus formation of Fbh1 & is prerequisite for the Fbh1 recombination function. (Mus musculus) PubMed

 4986.

The total GSH level was more significantly enhanced in the KP1 cells overexpressing gamma-GT2 than gamma-GT1 during nitrogen starvation. [gamma GT1,gamma GT2] (Mus musculus) PubMed

 4987.

Two sporulation-specific genes, spo13(+) and spo2(+), which are not required for progression of meiotic nuclear divisions, but are essential for sporulation, were analyzed.[Spo2, Spo13] (Mus musculus) PubMed

 4988.

Nip1/Ctp1 is a functional counterpart of Sae2/Com1 and CtIP.(Nip1/Ctp1) (Mus musculus) PubMed

 4989.

inactivation of the complex leads to loss of thiolation on tRNAs and to a thermosensitive decrease of viability associated with marked ploidy abnormalities and aberrant development(uridine tRNA thiolase Ctu1-Ctu2) (Mus musculus) PubMed

 4990.

These results suggest that Hsp90 plays a specific role in the S. pombe glucose/cAMP pathway.[Git10] (Mus musculus) PubMed

 4991.

SpHsp16.0 is likely to interact with denatured CS in the dissociated state, while SpHsp15.8 is likely to interact with CS in a large complex. [Hsp15.8] (Mus musculus) PubMed

 4992.

Slk1p and Sid2p play a role in forespore membrane assembly by facilitating recruitment of components of the secretory apparatus, such as Psy1p, to allow membrane expansion [Slk1 protein] (Mus musculus) PubMed

 4993.

Ers1 is a rapidly diverging protein essential for RNA interference-dependent heterochromatic silencing in Schizosaccharomyces pombe (Mus musculus) PubMed

 4994.

Atx1 acts as a copper carrier to deliver copper to Cao1. [Atx1, Cao1] (Mus musculus) PubMed

 4995.

We propose that chromatin assembly factor (CAF1) functions in heterochromatin maintenance by recruiting dislocated Swi6 during replication to replicated heterochromatin at the replication fork. [CAF1 (Pcf1,Pcf2,Pcf3)] (Mus musculus) PubMed

 4996.

The alpha-amino group of the d-alanyl moiety of the lysino-d-alanyl residue serves as a catalytic base in the same manner as the epsilon-amino group of Lys57 of the original spSR.[Serine racemase] (Mus musculus) PubMed

 4997.

Tn the yeast Schizosaccharomyces pombe, tdp1 mutant cells progressively accumulate DNA damage and rapidly lose viability in a physiological G0/quiescent state. (Mus musculus) PubMed

 4998.

Functionally distinct isoforms of Cik1 are differentially regulated by APC/C-mediated proteolysis. (Mus musculus) PubMed

 4999.

Degradation of Sre1 in the absence of Scp1 requires the ER-associated degradation (ERAD) components Ubc7, an E2 ubiquitin conjugating enzyme, and Hrd1, an E3 ubiquitin ligase.[Ubc7, Hrd1] (Mus musculus) PubMed

 5000.

Schizosaccharomyces pombe contains two tRNase Z(L) genes, designated sptrz1(+) and sptrz2(+) and both are essential for growth[sptrz1 and sptrz2] ] (Mus musculus) PubMed

 5001.

Dni1p plays a relevant role in co-ordinating membrane organization and cell wall remodelling during mating. [Dni1p] (Mus musculus) PubMed

 5002.

the 3.2 A resolution structure of Schizosaccharomyces pombe Xpot in complex with tRNA and RanGTP, and the 3.1 A structure of unbound Xpot, revealing both nuclear and cytosolic snapshots of this transport factor [Xpot] (Mus musculus) PubMed

 5003.

Data show that fission yeast kinesin-6 motor klp9p binds to the microtubule antiparallel bundler ase1p at the midzone at anaphase B onset [Klp9p]. (Mus musculus) PubMed

 5004.

Describe a model of cullin-RING ubiquitin ligase (CRL) control in which substrate availability toggles CRLs between COP9 signalosome and CAND1(TIP120A) cycles. (Mus musculus) PubMed

 5005.

the crystal structures of the C-terminal domain of the Saccharomyces cerevisiae Stn1 and the Schizosaccharomyces pombe Ten1 proteins are reported. (Ten1) (Mus musculus) PubMed

 5006.

The abnormal degradation of TRH and GnRH, and perhaps other neuropeptides N-terminally blocked with a pyroglutamyl moiety, by trypanosome PGP, may contribute to some of the endocrine lesions observed in African trypanosomiasis. [PGP] (Mus musculus) PubMed

 5007.

Genes for three proteins (PEX6, PEX10, PEX12) involved in glycosome biogenesis of Trypanosoma brucei were identified [PEX6, PEX10, PEX12] (Mus musculus) PubMed

 5008.

AUK1 plays an essential role in cytokinesis that cannot be affected by changes in the level of polo-like kinase; TbAUK1 is also the first identified protein that couples both mitosis and kinetoplast replication with cytokinesis in the trypanosome [AUK1] (Mus musculus) PubMed

 5009.

data indicate that trypanosomes utilize TRACK a RACK1 homologue to regulate the final stages of mitosis; disrupting the interaction between TRACK and its partners might be targeted in the design of novel therapies [TRACK] (Mus musculus) PubMed

 5010.

Results report the first functional characterisation of a Trypanosoma brucei basal body-cytoskeletal NIMA-related kinase (NRK) protein, TbNRKC [NRKC]. (Mus musculus) PubMed

 5011.

Data suggest that dDual targeting of a single tRNA(Trp) requires two different tryptophanyl-tRNA synthetases in Trypanosoma brucei. [tryptophanyl-tRNA synthetase] (Mus musculus) PubMed

 5012.

TbEIF4AI may be involved in protein synthesis while the properties and sequence of TbEIF4AIII indicate that it may be the orthologue of eIF4AIII, a component of the exon junction complex in mammalian cells (TbEIF4AI, TbEIF4AIII). (Mus musculus) PubMed

 5013.

IscS and IscU down-regulate the active mitochondrion of procyclic Trypanosoma brucei [Tbiscs, Tbiscu] (Mus musculus) PubMed

 5014.

The characterization of MCP6, a novel T. brucei MCF protein, is localized in the mitochondria. (Mus musculus) PubMed

 5015.

DOT1A and DOT1B influence the trypanosome cell cycle by regulating the degree of H3K76 methylation.[DOT1A, DOT1B] (Mus musculus) PubMed

 5016.

Data show that mitochondrial RNA binding proteins MRP1/MRP2 act as RNA matchmakers by stabilizing the RNA molecule in an unfolded conformation suitable for RNA-RNA hybridization [MRP1, MRP2]. (Mus musculus) PubMed

 5017.

findings show that TbAT1 and TbMRPA contribute independently to drug resistance, and the effects from combination of the two mutations were strictly additive [AT1; MRPA] (Mus musculus) PubMed

 5018.

Study reports purification a transcriptionally active enzyme through affinity chromatography of its essential subunit, RPB4, the enzyme preparation is active in both promoter-independent and promoter-dependent in vitro transcription assays. [RPB4 protein] (Mus musculus) PubMed

 5019.

Catalytic properties of recombinant TbPTR1 and inhibition by the archetypal antifolate methotrexate have been characterized and the crystal structure of the ternary complex with cofactor NADP+ and the inhibitor determined at 2.2 A resolution.(TbPTR1) (Mus musculus) PubMed

 5020.

The heteroheptameric Sm core structure varies between spliceosomal snRNPs, and that modulation of the Sm core composition mediates the recognition of small nuclear RNA-specific Sm sites.[U2 SnRNP] (Mus musculus) PubMed

 5021.

iPGAM is required for cell growth in procyclic T. brucei [iPGAM] (Mus musculus) PubMed

 5022.

T.brucei cap 2'-O methyltransferase (TbCom1) binds specifically to m7GpppN-terminated RNA and catalyzes the transfer of a methyl group from AdoMet to the 2nd transcribed nucleoside to form m7GpppNpNm (T.brucei cap 2'-O methyltransferase). (Mus musculus) PubMed

 5023.

the biological significance of tryparedoxin for hydroperoxide detoxification and its function in the parasite defence against oxidative stress (tryparedoxin). (Mus musculus) PubMed

 5024.

TbZFP3 is a novel regulator of developmental events in kinetoplastids that acts at the level of the post-transcriptional control of gene expression [TbZFP3] (Mus musculus) PubMed

 5025.

the identification and functional characterization of a T. brucei Dicer-like enzyme [Dcl1] (Mus musculus) PubMed

 5026.

Data show that UDP-glucose 4'-epimerase is essential for the production of UDP-galactose required for galactosylation of glycoproteins, which is essential for the survival of bloodstream form T. brucei [UDP-glucose 4'-epimerase]. (Mus musculus) PubMed

 5027.

Studies of the enzymatic activity of the T. brucei CK2s show that both the affinity for GTP and stimulation by polyamines have been lost and only the features of heparin inhibition and stimulation by polybasic peptides are conserved[CK2] (Mus musculus) PubMed

 5028.

RRP6 can be present independent of exosome association[RRP6] (Mus musculus) PubMed

 5029.

The essential Golgi-localizing T. brucei ARF1 has a primary role in the maintenance of both post-Golgi transport and endocytosis. (Mus musculus) PubMed

 5030.

the identification, structural and biochemical analyses of a novel trypanosomal TUTase, TbTUT4, which represents a minimal catalytically active RNA uridylyltransferase, is reported.[Tut4] (Mus musculus) PubMed

 5031.

In addition to the analysis of the crystal structure, 3D nuclear magnetic resonance interaction studies and docking experiments of 6-phosphogluconolactonase are reported here.[6-phosphogluconolactonase] (Mus musculus) PubMed

 5032.

Study shows that in the mammalian-infective bloodstream-stage of the African trypanosome, Trypanosoma brucei, SIR2rp1 localizes to the nucleus while SIR2rp2 and SIR2rp3 are both mitochondrial proteins. [SIR2rp1, SIR2rp2, SIR2rp3 proteins] (Mus musculus) PubMed

 5033.

a laboratory line of Trypanosoma brucei that adapted to high levels of resistance for the melaminophenyl arsenical drug melarsamine hydrochloride (Cymelarsan), had similarly lost TbAT1 and HAPT1 activity while retaining LAPT1 activity (HAPT1) (Mus musculus) PubMed

 5034.

KREPB4 is important for the structural integrity of approximately 20S editosomes, editing endonuclease activity, and the viability of T. brucei cells.[KREPB4] (Mus musculus) PubMed

 5035.

cyclin E1 forms complexes with CRK1 in promoting G1/S phase transition; with CRK2 in controlling the posterior morphogenesis during G1/S transition; with CRK3 in promoting passage across the G2/M checkpoint in the trypanosome.(cyclin E1) (Mus musculus) PubMed

 5036.

a novel member of the ISWI family of SWI2/SNF2-related chromatin-remodelling proteins (TbISWI) is involved in ES downregulation in Trypanosoma brucei.(ISWI) (Mus musculus) PubMed

 5037.

The catalytic mechanism of the Tpx peroxidase resembles that of atypical 2-Cys-peroxiredoxins but is distinct from that of the selenoenzymes [glutathione peroxidase-type tryparedoxin peroxidase] (Mus musculus) PubMed

 5038.

These data identify a distinct mechanism for regulating AdoMetDC in the parasite that suggests new strategies for the development of parasite-specific inhibitors of the polyamine biosynthetic pathway.[AdoMetDC] (Mus musculus) PubMed

 5039.

A new and unique role for centrin in the segregation of organelles without affecting their multiplication in the procyclic form of T. brucei, is revealed.[Centrin1] (Mus musculus) PubMed

 5040.

Crystal structures of Mevalonate diphosphate decarboxylase (MDD) from T. brucei (TbMDD, at 1.8 A resolution) and S. aureus (SaMDD, each diffracting to 2.3 A resolution) have been determined[mevalonate diphosphate decarboxylase ] (Mus musculus) PubMed

 5041.

TbPRMT5 is likely to be involved in novel methylation-regulated functions in trypanosomes, some of which may include RNA processing and/or translation.(TbPRMT5) (Mus musculus) PubMed

 5042.

Results describe the first eukaryotic cap 1 2'-O-ribose methyltransferase, TbMTr1, a member of a conserved family of viral and eukaryotic enzymes [TbMTr1]. (Mus musculus) PubMed

 5043.

Trimethylguanosine synthase (Tgs1)is responsible for hypermethylation of the m(7)G cap of both snRNAs and snoRNAs. [Tgs1] (Mus musculus) PubMed

 5044.

These results suggest that Trypanosoma brucei peptide deformylase (TbPDF2) is functionally linked to TbPDF1, and that it can influence the efficiency of oxidative phosphorylation [PDF2, PDF1]. (Mus musculus) PubMed

 5045.

Data suggest that Trypanosoma brucei Polo-like kinase is essential for basal body duplication, kDNA segregation and cytokinesis. (Mus musculus) PubMed

 5046.

The ADP ribosylation factor 1 (TbARF1) protein remains essential for the viability of these procyclic cells but the major effect of TbARF1-depletion is enlargement of the lysosome.[ARF1] (Mus musculus) PubMed

 5047.

JBP2 stimulates de novo J synthesis in newly generated telomeric arrays in blood stream form Trypanosoma. (Mus musculus) PubMed

 5048.

The loss of the trypanosomatid-specific proteins p34 and p37 correlates with a diminution in 5S rRNA levels as well as a decrease in ribosome activity and an alteration in ribosome biogenesis.[p34,p37] (Mus musculus) PubMed

 5049.

Slow growth and chromosome segregation defect phenotypes are completely reversed upon inducible expression of AGO1, demonstrating the role of AGO1 in chromosome segregation and RNA silencing.[AGO1] (Mus musculus) PubMed

 5050.

TbeIF2K2 is a transmembrane glycoprotein expressed both in procyclic and in bloodstream forms.[eIF2 alpha kinase] (Mus musculus) PubMed

 5051.

TbUBP1 and TbUBP2 may be relatively nonspecific RNA-binding proteins and that specific effects of overexpression or depletion could depend on competition between various different proteins for RNA binding.[UBP1, UBP2] (Mus musculus) PubMed

 5052.

These results suggest that CFB2 is required for bloodstream-form trypanosome cytokinesis.[CFB2] (Mus musculus) PubMed

 5053.

p34 and p37 regulate NOPP44/46 cellular localization by facilitating their association with exportin 1 [p34, p37] (Mus musculus) PubMed

 5054.

Results describe two Tousled-like kinase homologs, TLK1 and TLK2, in Trypanosoma brucei, but only TLK1 plays an essential role in cell growth. [TLK1 and TLK2] (Mus musculus) PubMed

 5055.

Depletion of the Trypanosoma brucei MTR4-like protein TbMTR4 caused growth arrest and defects in 5.8S rRNA processing similar to those seen after depletion of the exosome.[MTR4] (Mus musculus) PubMed

 5056.

These data suggest that ICP (cysteine peptidase inhibitor) has a role in controlling the differentiation process and virulence through the modulation of Csyteine peptidase activity. [ICP} (Mus musculus) PubMed

 5057.

biochemical evidence is provided that TbCgm1 is a capping enzyme.[TbCGM1] (Mus musculus) PubMed

 5058.

Protein sorting by hydrodynamic forces helps to protect trypanosomes against complement-mediated immune destruction in culture and possibly in infected mammals. [VSG] (Mus musculus) PubMed

 5059.

These results indicate that the overall structure of the C-terminal tail influences the HK activity of TbHK1.(TbHK1) (Mus musculus) PubMed

 5060.

Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing (Metacaspase 2). (Mus musculus) PubMed

 5061.

TbUBP and TbUBP2 may accentuate developmental regulation of the Tb927.3.4070-927.3.4110 mRNAs stability.[UBP1, UBP2] (Mus musculus) PubMed

 5062.

Dual roles for the exoribonuclease, DSS-1, in degradation of 12S rRNA maturation by-products and as part of a mitochondrial RNA surveillance pathway that eliminates stalled 12S processing intermediates (DSS-1). (Mus musculus) PubMed

 5063.

The Gup1p from T. brucei (tbGup1p) strongly prefers C14:0 and C12:0 over C16:0 and C18:0, whereas yeast Gup1p strongly prefers C16:0 and C18:0.[Gup1] (Mus musculus) PubMed

 5064.

First reported molecular component of the tripartite attachment complex, connnecting kinetoplast DNA to the flagellar basal body. (p166) (Mus musculus) PubMed

 5065.

KREPA6 is essential for the structural integrity and presence of 20S editosomes and for cell viability.(KREPA6) (Mus musculus) PubMed

 5066.

findings show that histone acetyltransferase 3 (HAT3) is responsible for H4K4 acetylation [HAT3] (Mus musculus) PubMed

 5067.

Together, these results suggest that protein phosphatase 5(PP5) positively regulates the function of Hsp90 to maintain cellular homeostasis during proteotoxic stresses in T. brucei. [PP5, Hsp90] (Mus musculus) PubMed

 5068.

TbHTD2 can rescue the respiratory deficient phenotype of the yeast knock-out strain and restore the lipoic acid content, is localized in the mitochondrion and exhibits hydratase 2 activity.[TbHTD2] (Mus musculus) PubMed

 5069.

Deletion of the TbALG3(alpha-mannosyltransferase)gene involved in site-specific N-glycosylation and N-glycan processing (Mus musculus) PubMed

 5070.

TbTim17 is the translocator of nuclear encoded mitochondrial proteins and its expression is regulated according to mitochondrial activities in T. brucei. [Tim17] (Mus musculus) PubMed

 5071.

A trypanosomal golgin, TbG63, is identified and characterized showing that it has a C-terminal membrane anchor and an N-terminus that projects into the cytoplasm.[TbG63] (Mus musculus) PubMed

 5072.

These results indicate p67 plays an essential role in maintenance of normal lysosomal structure and physiology in bloodstream-stage African trypanosomes. (LAMP-like protein p67) (Mus musculus) PubMed

 5073.

These data suggest that the mechanism by which RBP16 facilitates RNA editing involves its capacity to modulate RNA secondary structure and promote gRNA/pre-mRNA annealing. (Mus musculus) PubMed

 5074.

TbMP42 is required for both endonucleolytic cleavage steps of RNA editing, but not for any of the subsequent steps of the editing cycles. (TbMP42) (Mus musculus) PubMed

 5075.

Depletion of trypanosome CAF1 delayed deadenylation and degradation of constitutively expressed mRNAs (CAF1). (Mus musculus) PubMed

 5076.

Data show that duplication of the bilobed structure required for Golgi duplication is dependent on the single polo-like kinase (PLK) homologue in T. brucei (TbPLK) [Polo-like kinase]. (Mus musculus) PubMed

 5077.

A mitochondrial poly(A) polymerase, termed KPAP1, was identified and characterized.(KRAP1) (Mus musculus) PubMed

 5078.

ethanolamine-phosphoglycerol is also present in eukaryotic elongation factor 1A of the protozoan parasite Trypanosoma brucei, indicating that this unique protein modification is of ancient origin[eukaryotic elongation factor 1A] (Mus musculus) PubMed

 5079.

Initiation of cytokinesis is independent of sister chromatid cohesion or cohesin release following SCC1 cleavage. [SSC1] (Mus musculus) PubMed

 5080.

TbRGG2 is an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages [TbRGG2] (Mus musculus) PubMed

 5081.

Five crystal structures of the PTS1 binding domain of TbPEX5 were determined, each in complex with a hepta- or decapeptide corresponding to a natural or nonnatural PTS1 sequence.[PTS1 AND PEX5] (Mus musculus) PubMed

 5082.

The data suggests a Zn(2+)-dependent metal ion catalysis mechanism for the ribonucleolytic activity of TbMP42 (TbMP42). (Mus musculus) PubMed

 5083.

Data show that alternative editing of the mitochondrial cytochrome c oxidase III mRNA in Trypanosoma brucei produces a novel DNA binding protein, alternatively edited protein 1 (AEP-1) [AEP-1]. (Mus musculus) PubMed

 5084.

Results obtained indicate that TbDRBD3 binds to a subset of developmentally regulated mRNAs encoding membrane proteins, and that this association promotes the stabilization of the target transcripts (TbDRBD3). (Mus musculus) PubMed

 5085.

PLK was found to appear in late S phase and persist in G2/M phase but vanish in G1 phase. [PLK] (Mus musculus) PubMed

 5086.

TbTFIIS1 and TbTFIIS2-1,two trypanosome homologues of transcription elongation factor TFIIS, are required for normal cell growth. [TbTFIIS1 and TbTFIIS2-1] (Mus musculus) PubMed

 5087.

RNAi silencing of TbSLS1-4 in bloodstream trypanosomes led to rapid growth arrest and eventual cell death.[TbSLS1, 2, 3 & 4] (Mus musculus) PubMed

 5088.

P34 and P37 are involved in the ribosomal biogenesis pathway. [P34, P37] (Mus musculus) PubMed

 5089.

Results suggest that Trypanosoma brucei Centrin4 is involved in processes that coordinate karyokinesis and cytokinesis [Centrin4]. (Mus musculus) PubMed

 5090.

Loss of MIX had a major effect on cytochrome c oxidase activity, the mitochondrial membrane potential, and the production of mitochondrial ATP. [MIX] (Mus musculus) PubMed

 5091.

regulation of endocytosis is a physiological function of glycosylphosphatidylinositol-specific phospholipase C in bloodstream T. brucei. (Mus musculus) PubMed

 5092.

TbRACK1 is a functional component of the trypanosome ribosome which associates with eukaryotic elongation factor 1A Inactivation of TbRACK1 showed that cytokinesis is selectively inhibited when translation is disrupted. [RACK1] (Mus musculus) PubMed

 5093.

The kinetoplastid Trypanosoma brucei Selenophosphate synthetase genes were cloned and the protein overexpressed and purified to apparent homogeneity. (Mus musculus) PubMed

 5094.

KMP-11 is a flagellar protein playing critical roles in regulating cytokinesis in both forms of the trypanosomes. [Kmp-11] (Mus musculus) PubMed

 5095.

Glyoxalase II functions as general trypanothione thioesterase independent of ketoaldehyde detoxification. [Glyoxalase II] (Mus musculus) PubMed

 5096.

The 3'-UTRs of MspA, MspB and MspC are responsible for their differential expression. [MspA, MspB, MspC] (Mus musculus) PubMed

 5097.

POLID is a third essential DNA Pol required for kDNA replication. [POLID] (Mus musculus) PubMed

 5098.

TbNT11.1, has been functionally expressed in null mutants of Leishmania that are deficient in purine nucleoside or nucleobase uptake and identified as a purine nucleobase transporter. And TbNT12.1, reveals that it is an adenine/pentamidine transporter. (Mus musculus) PubMed

 5099.

These results provide evidence for TAX-2 function within the axoneme.[Tax-2] (Mus musculus) PubMed

 5100.

A new function of the mitochondrial topoisomerase II (TbTOP2mt) was reported. (TbTOP2mt) (Mus musculus) PubMed

 5101.

TbGT8 encodes a UDP-GlcNAc: beta-Gal-GPI beta1-3 N-acetylglucosaminyl transferase which may also influence the processing of the poly N-acetyllactosamine-containing asparagine-linked glycans. [TbGT8] (Mus musculus) PubMed

 5102.

the five-protein complex CPC-TbTLK1-TbKIN-B plays key roles in regulating chromosome segregation in the early phase of mitosis [Tousled-like kinase TbTLK1] (Mus musculus) PubMed

 5103.

The 82kDa TbncPAP1 is essential for viability of procyclic and bloodstream forms of T. brucei. The recombinant 54kDa TbncPAP2 showed a poly(A) polymerase activity as an individual polypeptide[TbncPAP1, TbncPAP2] (Mus musculus) PubMed

 5104.

the mitochondrial porin identified in T. brucei is the main metabolite channel in the outer membrane and therefore the functional orthologue of VDAC.[MITOCHONDRIAL PORIN] (Mus musculus) PubMed

 5105.

The TbMTr1 complex specializes the SLA1 H/ACA snoRNP for efficient processing of multiple modifications on the spliced leader RNA substrate.[TbMTr1] (Mus musculus) PubMed

 5106.

Trypanosoma brucei UDP-glucose:glycoprotein glucosyltransferase is essential for parasite growth and survival at 40 degrees C.[UDP-glucose:glycoprotein glucosyltransferase] (Mus musculus) PubMed

 5107.

While the individual JBP1 null and JBP2 null trypanosomes have reduced J levels, the deletion of both JBP1 and JBP2 generates a cell line that completely lacks base J but still contains glucosyl-transferase activity (JBP1 and JBP2). (Mus musculus) PubMed

 5108.

study reports that transcription mediated by pol I requires TbRPB7, a dissociable subunit of the pol II complex; TbRPB7 was found to interact with two pol I-specific subunits, TbRPA1 and TbRPB6z [TbRPB7] (Mus musculus) PubMed

 5109.

Peroxin 13 is essential for the parasite; depletion by RNA interference results in mislocalization of glycosomal proteins and death of the parasites. (Mus musculus) PubMed

 5110.

Both PTB1 and PTB2 were shown to regulate mRNA stability;and are essential for trans-splicing of genes containing C-rich polypyrimidine tracts; PTB1, but not PTB2, also affects cis-splicing. [PTB1, PTB2] (Mus musculus) PubMed

 5111.

TOR1 and TOR2 proteins may function as major regulators of cell growth and cytokinesis (TOR1, TOR2). (Mus musculus) PubMed

 5112.

Screening of candidate palmitoyl acyltranferases identified a single enzyme, TbPAT7, that is necessary for calflagin palmitoylation and flagellar membrane targeting.[TbPAT7] (Mus musculus) PubMed

 5113.

RNAi silencing reveals an essential role for RABL5 in trypanosome flagellum construction.[RABL5] (Mus musculus) PubMed

 5114.

The structure of TbUrm1 (ubiquitin-related modifier 1) shares the highly conserved structure among its ubiquitin superfamily, and studies will shed more light on the road exploring evolution of ubiquitin superfamily: [Urm1] (Mus musculus) PubMed

 5115.

study identifes the developmental regulator, TbZFP3, a CCCH-class predicted RNA binding protein, as an isoform-specific regulator of Procyclin surface coat expression in trypanosomes [ZFP3] (Mus musculus) PubMed

 5116.

TbPRMT7 is a Type III PRMT, and its robust activity and presence in numerous complexes suggest it plays multiple roles during the complex T. brucei life cycle [PRMT7] (Mus musculus) PubMed

 5117.

these results indicate that both KREX1 and KREX2 are important for retention of other proteins in editosomes, and suggest that the reduction in cell viability.[KREX1, KREX2] (Mus musculus) PubMed

 5118.

The interaction between U2AF35 and U2AF65 was very weak or not detectable. However, as in other eukaryotes, the interaction between U2AF65 and SF1 was strong.[U2AF35,U2AF65 and SF1] (Mus musculus) PubMed

 5119.

TbAUK1 aurora kinase is essential for infection in the mammalian host and can be targeted with small-molecule inhibitors. [AUK1] (Mus musculus) PubMed

 5120.

Tb-SUMO interacts with human Ubc9 through residues located on the beta-sheet of Tb-SUMO, which is also similar to that of SUMO-1 and Smt3 suggesting the evolutionary conservation of SUMO and sumoylation in eukaryotes.[SUMO] (Mus musculus) PubMed

 5121.

Study identifies tbRAP1 as an intrinsic component of the T. brucei telomere complex and a major regulator for silencing variant surface glycoprotein expression sites, [Rap1] (Mus musculus) PubMed

 5122.

Three acid phosphatases (ACP) from lysosomal fractions of T. brucei are purified and described. [ACP I, ACP II, ACP III] (Mus musculus) PubMed

 5123.

Depletion studies using RNAi showed that there was a modest growth inhibition in procyclic cells but lethality in bloodstream cells, showing that MORN1 is an essential protein in the bloodstream form of the organism.[MORN1] (Mus musculus) PubMed

 5124.

These data demonstrate that prozyme mediated activation of S-adenosylmethionine decarboxylase is a common mechanism required to regulate S-adenosylmethionine decarboxylase activity in the trypanosomatids.[prozyme] (Mus musculus) PubMed

 5125.

A new member of the FHIT protein family, designated HIT-45, has been identified and sequenced. This enzyme exhibited typical dinucleoside triphosphatase activity (EC 3.6.1.29), having its highest specificity for diadenosine triphosphate (ApppA). (HIT-45) (Mus musculus) PubMed

 5126.

U2B associates with U2-40K, and U2-40K contacts the U2-specific Sm core complex.[U2B] (Mus musculus) PubMed

 5127.

Gene knockout indicates that ethanolamine-phosphate cytidylyltransferase s essential for growth and survival for the pathogenic stage of the African trypanosome.[ethanolamine-phosphate cytidylyltransferase] (Mus musculus) PubMed

 5128.

suggest that both RNA-specific and life cycle stage-specific factors impact MRP1/2 and RBP16 functions[RBP16, MRP1 and MRP2] (Mus musculus) PubMed

 5129.

In the absence of glycosylphosphatidylinositol, the procyclin is N-glycosylated, transported to the lysosomal compartment, and secreted into the culture supernatant. [procyclin] (Mus musculus) PubMed

 5130.

The 2.3 A resolution structure of the C-terminal domain of tTFIIB, is described.[TFIIB] (Mus musculus) PubMed

 5131.

CRK9 could be specifically involved in regulating cytokinetic initiation in the procyclic form of Trypanosoma brucei.[CRK9] (Mus musculus) PubMed

 5132.

Trypanosome-suppressive immunomodulating factor (TSIF) knock-down trypanosomes died within 2 days, indicating that TSIF may be essential for parasite biology.[TSIF] (Mus musculus) PubMed

 5133.

A putative, highly divergent homolog of Sec61beta was identified in E. cuniculi. NOTE: This gene (BK005765) not annotated yet (acknowledged in paper) and so currently no Gene record for it. Located between ECU09_0940 (860433) and ECU09_0950 (860434). (Mus musculus) PubMed

 5134.

Study describes that an endochitinase, CHT1 a chitin synthase, CHS1 and 2 subtilisin-like proteases, SLP1 and SLP2 are induced during meront to sporont development.[CHS1, CHP1, SLP1, SLP2] (Mus musculus) PubMed

 5135.

When expressed in S. cerevisiae, EcTom70 inserts with the correct topology into the outer membrane of mitochondria but is unable to complement the growth defects of Tom70-deficient yeast. [Tom70} (Mus musculus) PubMed

 5136.

The crystal structure of a ferredoxin-like protein from Thermoanaerobacter tengcongensis (Tflp), is reported. (Mus musculus) PubMed

 5137.

VHv1.1 is at least in part responsible for the inhibitory effect of Campoletis sonorensis ichnovirus on host larval growth and development[VHv1.1] (Mus musculus) PubMed

 5138.

Detailed expression profiles of let-7 microRNA in the whole life cycle and cultured cell line of silkworm show a clear association with ecdysone pulse and a variety of biological processes. (Mus musculus) PubMed

 5139.

Based on a comparison of the normal W-chromosome and 7 translocation and W-deletion strains we present a map of Fem (female determining gene) relative to the 12 W-specific RAPD markers.[Fem] (Mus musculus) PubMed

 5140.

Bombyx mori midgut membrane protein P252, which binds to Bacillus thuringiensis Cry1A, is a chlorophyllide-binding protein, and the resulting complex has antimicrobial activity. (Mus musculus) PubMed

 5141.

The pp-1 gene contains 17 exons and codes for two pacifastin-related precursors of different length. [PP1] (Mus musculus) PubMed

 5142.

In diapause eggs, an abrupt decrease in phosphorylation of GSK-3beta was found with the onset of diapause. [GSK-3beta] (Mus musculus) PubMed

 5143.

mgtC is needed for growth of B. cenocepacia in magnesium-depleted medium and for bacterial survival within murine macrophages. (mgtC) (Mus musculus) PubMed

 5144.

data demonstrate that HtrA(BCAL2829) is a virulence factor in B. cenocepacia [HtrA] (Mus musculus) PubMed

 5145.

Steady-state kinetic analysis of the BCAL0207 gene product demonstrated that it has 4-hydroxyphenylpyruvic acid dioxygenase (HppD) activity.[HppD] (Mus musculus) PubMed

 5146.

the conversion from rough wild type to shv in B. cenocepacia correlates with reduced biofilm formation and virulence, and we determined that BCAS0225 is one gene involved in the regulation of these phenotypes [BCAS0225] (Mus musculus) PubMed

 5147.

this study is the first demonstration that the RpoN regulon in B. cenocepacia is involved in delaying phagolysosomal fusion, thereby prolonging bacterial intracellular survival within macrophages. [RpoN in strain k56-2] (Mus musculus) PubMed

 5148.

Despite strong sequence similarity, the differences between lectin A and PA-IIL in their specificity, binding site and oligomerization mode indicate that the proteins should have different roles in the bacteria. [lectin A] (Mus musculus) PubMed

 5149.

B. cenocepacia rpoE is required for bacterial growth under certain stress conditions and for the ability of intracellular bacteria to delay phagolysosomal fusion in macrophages.[RpoE] (Mus musculus) PubMed

 5150.

data show that AtsR is involved in the regulation of genes required for virulence in B. cenocepacia K56-2, including genes encoding a T6SS.[AtsR in strain K56-2] (Mus musculus) PubMed

 5151.

Results suggest that the enzyme favours the formation of GDP-mannose instead of mannose catabolism, thus channelling precursors to the formation of glycoconjugates.[BceA(J)] (Mus musculus) PubMed

 5152.

This study demonstrates that the orphan LuxR homolog CepR2 contributes to the quorum-sensing regulatory network in two distinct strains of B. cenocepacia.[CepR2] (Mus musculus) PubMed

 5153.

ZmpA and ZmpB may influence the resistance of B. cenocepacia to host antimicrobial peptides as well as alter the host protease/anti-protease balance in chronic respiratory infections. [Zinc metalloprotease A/Zinc metalloprotease B/B. cenocepacia K56-2] (Mus musculus) PubMed

 5154.

VP22 of the CVI988/Rispens vaccine strain has an intercellular-trafficking function which might allow it to serve as a potential alternative delivering protein instead of virulent strains' VP22. [VP22] (Mus musculus) PubMed

 5155.

The results suggested that the VP5 of Marine Birnavirus is a novel anti-apoptosis gene, which could regulate the cell apoptosis-off system.[VP5 gene] (Mus musculus) PubMed

 5156.

X-ray diffraction data of Thermotoga petrophila endo-1,5-alpha-L-arabinanase were collected to a resolution of 2.86 A using synchrotron radiation.[endo-1,5-alpha-L-arabinanase ] (Mus musculus) PubMed

 5157.

Eugenol oxidase is a flavin-adenine dinucleotide (FAD)-containing oxidase found to be most active with eugenol; its substrate reactivity is strikingly different compared with fungal vanillyl alcohol oxidase [eugenol oxidase] (Mus musculus) PubMed

 5158.

Cyclic GMP suppresses pseudopod formation in the back of the cell, whereas the soluble guanylyl cyclase (sGC) protein refines pseudopod formation at the leading edge.[Soluble guanyl cyclase] (Mus musculus) PubMed

 5159.

These results suggest that P64's function is to condense the large genome of this virus and assist in packaging this genome into its virion.[P64] (Mus musculus) PubMed

 5160.

Mutants of DntR in which residues lining the proposed inducer-binding cavity were modified were constructed in order to identify the structural elements involved in inducer binding and to investigate the mechanism of transcriptional regulation by DntR. (Mus musculus) PubMed

 5161.

A novel peptidase (BcepAP)in family M61 with specificity for N-terminal acidic residues of peptide substrates was identified. [BcepAp] (Mus musculus) PubMed

 5162.

The conformational transition of B. cepacia lipase was dependent on the solvent. (Mus musculus) PubMed

 5163.

CAD is essential for itaconic acid production in A. terreus. [Cad] (Mus musculus) PubMed

 5164.

The A. terreus NADP-GDH was more stable and showed non-competitive ammonium inhibition with respect to glutamate compared to A. niger NADP-GDH. [NADP-GDH] (Mus musculus) PubMed

 5165.

The amounts of ChA and ChC were significantly reduced when exposed to 75 degrees C for 24 h. [ChA, ChC] (Mus musculus) PubMed

 5166.

Expression of chi46 is induced by exposure to the cell walls of plant pathogens and living pathogens, suggesting a role in plant disease resistance. [Chi46] (Mus musculus) PubMed

 5167.

The cDNA and partial genomic sequence of ADF (actin-depolymerizing factor) were identified and its role in actin binding and host invasion demonstrated. [ADF] (Mus musculus) PubMed

 5168.

HSP70 is a structural component of the synaptonemal complex (SC), and may be involved in SC functions such as chromosomal pairing, recombination, or disjunction. [HSP70] (Mus musculus) PubMed

 5169.

CYP619C2 and CYP619C3 are involved in the biosynthesis of patulin. [CYP619C2, CYP619C3] (Mus musculus) PubMed

 5170.

N-terminal extension of TrxRh1 was necessary to import the protein into the organelles and TrxRh2 had no N-terminal targeting signal but was efficiently targeted to hydrogenosomes. [TrxRh1, TrxRh2] (Mus musculus) PubMed

 5171.

T. vaginalis trimethylguanosine synthase exhibits substrate specificity and amino acid requirements typical of an RNA cap-specific, m(7)G-dependent N2 methyltransferase (trimethylguanosine synthase). (Mus musculus) PubMed

 5172.

FDP reduces dioxygen to water but is unable to utilize nitric oxide as a substrate. [FDP] (Mus musculus) PubMed

 5173.

Myb2 and Myb3 coactivate ap65-1 transcription against Myb1 repression through competitive promoter binding. [ap65-1, Myb1, Myb2 and Myb3] (Mus musculus) PubMed

 5174.

Study on the molecular basis for the DNA recognition of Myb1 DNA-binding domain (Myb1). (Mus musculus) PubMed

 5175.

A post-transcriptional regulatory mechanism by iron for tvcp4 mediated by IRE/IRP-like interactions was found [cysteine proteinase 4, tvcp4]. (Mus musculus) PubMed

 5176.

We propose that induction of collagenase-1 by IL-1alpha in both WF and NF depends on a unique combination of cell type-specific signaling pathways. [COLLAGENASE-1] (Mus musculus) PubMed

 5177.

Expression of 11beta-HSD1 may be fundamental in the regulation of CSF secretion and the local generation of cortisol may represent a pathophysiological mechanism underlying cortisol-dependent neuroendocrine diseases.[11beta-hsd1]. (Mus musculus) PubMed

 5178.

Study demonstrates the activity and gene expression of large neutral amino acid transporters Lat1 (SLC7A5) and LAT2 (SLC7A8)in the rabbit retina. LAT1 is involved in retinal uptake and intravitreal elimination of L-Phe.[Lat1 (SLC7A5) / LAT2 (SLC7A8)] (Mus musculus) PubMed

 5179.

These data provide a mechanism by which constitutively and transiently expressed H1 forms can tightly regulate RyR1 channel activity in response to changing levels of expression and degradation of H1 proteins.[RyR1] (Mus musculus) PubMed

 5180.

our studies suggest a novel regulatory mechanism in which phosphorylation of Munc18b operates vesicle docking and fusion in regulated exocytosis [Munc18b] (Mus musculus) PubMed

 5181.

characterization the full-length cDNA sequence of the rabbit BK channel beta1 subunit gene, which will set the basis for further investigation in the transcriptional regulation of this gene. (Mus musculus) PubMed

 5182.

In mouse and rabbit myocytes overexpressing CaMKIIdelta(C) by means of adenovirus-mediated gene transfer, recovery of fractional shortening and Ca transients was not impaired during late acidosis but even slightly improved.[CaMKIId] (Mus musculus) PubMed

 5183.

expression of endogenous rabbit peroxisome proliferator-activating receptor and VEGFR2 were significantly increased in the growth factor-transduced muscles, but these inductions were efficiently prevented by 15-LO-1. (VEGFR2) (Mus musculus) PubMed

 5184.

The data show that protein kinase B (Akt) activation promotes mitochondrial respiration and ATP production in toxicant-injured renal proximal tubular cells. [protein kinase B (Akt)] (Mus musculus) PubMed

 5185.

The Ser or Thr at position 512 is the most important determinant of functional differences in apparent affinity for substrate and cations, and the cation and substrate binding sites are located in close proximity to one another: NaDC1 (Mus musculus) PubMed

 5186.

Novel localization of pIgR to the regulated secretory pathway of lacrimal gland acinar cells and its secretion therefrom may be affected by its novel interaction with Rab3D. (Mus musculus) PubMed

 5187.

Renal proximal tubular cell (RPTC)proliferation after plating is mediated by HB-EGF produced through an autocrine/paracrine mechanism and RPTC proliferation following oxidant injury is mediated by Src without involvement of HB-EGF. [HB-EGF] (Mus musculus) PubMed

 5188.

analysis of ligand binding in cytochrome P450 1A2 [CYP1A2] (Mus musculus) PubMed

 5189.

REP52 is synthesized and secreted in a tissue-specific manner by the mid (region 6) and distal (region 7) corpus epididymidis and associates weakly with the sperm surface overlying the principal piece of the tail [REP52]. (Mus musculus) PubMed

 5190.

Chronic upregulation/activation of CaMKIID, and protein kinase D (PKD) in heart failure shifts histone deacetylase 5 (HDAC5) out of the nucleus, derepressing transcription of hypertrophic genes. (Mus musculus) PubMed

 5191.

G(q)-dependent signalling by the lysophosphatidic acid receptor LPA(3) in gastric smooth muscle: reciprocal regulation of MYPT1 phosphorylation by Rho kinase and cAMP-independent PKA [LPA3, MYPT1] (Mus musculus) PubMed

 5192.

results support an earlier observation that the combination of benzphetamine and cyt b 5 binding produce a synergy leading to unique active site structural changes when both are bound[cytochrome P450 2B4] (Mus musculus) PubMed

 5193.

Rabbit L-gulonate 3-dehydrogenase was crystallized using the oil-microbatch method at 295 K [L-gulonate 3-dehydrogenase] (Mus musculus) PubMed

 5194.

eIF5B or eIF5B/eIF3 also promote Met-tRNA(iMet) binding to IRES-40S complexes, forming 48S complexes that can assemble elongation-competent ribosomes.[eIF2] (Mus musculus) PubMed

 5195.

Cardiotonic action of dopamine is due to dopamine D1 receptor and beta2 adrenergic receptor mediated increases in L-type calcium current. (Mus musculus) PubMed

 5196.

binding pocket complementary to the reactive substrate fragment which contains all the active site residues needed to catalyze the reaction of the substrate piece or of the whole substrate [glycerol 3-phosphate dehydrogenase ] (Mus musculus) PubMed

 5197.

iPLA(2)gamma is required for the prevention and repair of basal lipid peroxidation [iPLA2gamma] (Mus musculus) PubMed

 5198.

Report complex regulation of store-operated Ca2+ entry pathway by protein kinase C(PKC)-epsilon in vascular smooth muscle cells. (Mus musculus) PubMed

 5199.

Oxytocin-induced contractions within rat and rabbit ejaculatory tissues are mediated by vasopressin V1A receptors and not oxytocin receptors. (Mus musculus) PubMed

 5200.

flow unilaterally attenuates FGF8/gap junction-mediated repression of Nodal on the left side, integrating gap junctional communication and FGF8 into the flow-based mechanism of symmetry breakage in the vertebrate embryo[ Nodal ] (Mus musculus) PubMed

 5201.

results suggest that NK2 & NK3 but not NK1 receptors are involved in the excitatory modulation of inspiratory activity [NK1, NK2 AND NK3 RECEPTOR] (Mus musculus) PubMed

 5202.

TIMP-3 is downregulated in a distinct subpopulation of atherosclerotic foam cells which have increased matrix metalloproteinase 14 (MT-MMP/MMP-14). (Mus musculus) PubMed

 5203.

investigated whether oxidant stress plays a role in Ang II-induced AT1R upregulation and its relationship to the transcription factor activator protein 1 (AP1) in CHF rabbits and in the CATHa neuronal cell line [AP-1, Ang II and Jnk]. (Mus musculus) PubMed

 5204.

Findings demonstrate that phosphodiesterase 3B (PDE3B) is present in rabbit erythrocytes and are consistent with the hypothesis that PDE3 activity regulates cAMP levels associated with a signaling pathway activated by iloprost in these cells. (Mus musculus) PubMed

 5205.

Inhibition of farnesyl-diphosphate farnesyltransferase (squalene synthase) changed macrophage/lipid-rich coronary plaques of hypercholesterolaemic rabbits into fibrous lesions. (Mus musculus) PubMed

 5206.

Study isolated two synaptopodin 2 isoforms from rabbit stomach that corresponded to known types of human synaptopodin 2 and synaptopodin 2 bound to Ca2+-calmodulin.[Synaptopodin 2] (Mus musculus) PubMed

 5207.

enhancement of gap junction intercellular communication is activated by ET-1 via modulating the expression of connexin43, and plays an important role in the pathogenesis of cerebral vasospasm. (Mus musculus) PubMed

 5208.

FGF5 gene could be the potential major gene affecting wool yield or link with the major gene, and polymorphic loci B and C may be used as molecular markers for im-proving wool yield in angora rabbits (Mus musculus) PubMed

 5209.

Alpha-T was found in all semen fractions. Half of the total gamma (+beta)-T was found in germ cells, while 50% of total delta-T was accumulated in seminal plasma [alpha-, gamma (+beta)- and delta-tocopherol]. (Mus musculus) PubMed

 5210.

CRPV early protein 2 activates the expression of MMP-9 in-trans through AP-1 and ERK1 and may contribute to cancer development and progression via this mechanism within the animal model[AP-1, ERK1, MMP-9] (Mus musculus) PubMed

 5211.

two binding sites may be part of the extracellular (stereospecific) and intracellular (non-stereospecific) sugar interaction sites of SGLT1[Sodium-Glucose Transporter 1 ] (Mus musculus) PubMed

 5212.

Novel insights of the gastric gland organization revealed by chief cell specific expression of moesin. (Mus musculus) PubMed

 5213.

Role of CuZn superoxide dismutase (SOD1) on carotid body function in heart failure rabbits. (Mus musculus) PubMed

 5214.

The ratio of non-synonymous to synonymous substitutions is significantly higher in peptide-binding-site codons than non-PBS codons. The high ratio at PBS codons suggests that the rabbit DQA locus may have been under intense selection. DQA. (Mus musculus) PubMed

 5215.

Protein kinase A-mediated phosphorylation of the transporter represents a further mechanism in the regulation of SGLT1-mediated glucose transport in epithelial cells[SGLT1] (Mus musculus) PubMed

 5216.

Report down-regulation of connexin 43 after load-induced hypertrophy in vitro. (Mus musculus) PubMed

 5217.

both DJ-1 and PINK1, and DJ-1 and alpha-Synuclein were positive at 8 h of reperfusion in the same motor neurons, which eventually die[DJ-1] [PINK1] [alpha-Synuclein] (Mus musculus) PubMed

 5218.

Indicate that the rabbit provides a relevant model, easily used in laboratories, to study the role of cardiac beta(3)-adrenoceptors in physiological conditions. (Mus musculus) PubMed

 5219.

Angiotensin II inhibits the Na+/K+ pump alpha 1 subunit via protein kinase c epsilon-dependent activation of NADPH oxidase subunits. (Mus musculus) PubMed

 5220.

Quercetin inhibited myocardial ischemia-reperfusion-induced NOX2 (NADPH oxidase 2) and iNOS (nitric oxide synthase 2) mRNA and protein expression. (Mus musculus) PubMed

 5221.

There were no differences in NCX surface distribution or in the spatial relationship to caveolin 3.[NCX, Vaveolin-3] (Mus musculus) PubMed

 5222.

results suggest a mechanism whereby nebulin specifies the minimum thin filament length and sarcomere length regulates and coordinates pointed-end dynamics to maintain the relative overlap of the thin and thick filaments during myofibril assembly [nebulin] (Mus musculus) PubMed

 5223.

substantial binding between junctophilin-2 and TRPC3 suggests that junctophilin-2 can be a regulatory protein of TRPC3 and/or TRPC3-mediated Ca(2+) homeostasis in skeletal m[TRPC3] (Mus musculus) PubMed

 5224.

hypercholesterolemia increases expression of connexin43 in rabbit aortic valve. results suggest that alterations in gap junctional intercellular communication via connexin43 may play a role in development of aortic valve sclerosis[connexin43] (Mus musculus) PubMed

 5225.

fibronectin expression in response to the acute mechanical strain resembling aortic regurgitation is upregulated primarily via JNK[fibronectin] (Mus musculus) PubMed

 5226.

SAP97 contributes to isoform specific organization of HCN channels within specific domains in the sinoatrial node of the rabbit.[SAP97] (Mus musculus) PubMed

 5227.

These data suggest that CLIC2 can interact with RyR1 and modulate its channel activity.[RyR1] (Mus musculus) PubMed

 5228.

function of VEGF-B in the vascular system is to act as a "survival," rather than an "angiogenic" factor and that VEGF-B inhibition may offer new therapeutic opportunities to treat neovascular diseases[VEGF-B] (Mus musculus) PubMed

 5229.

Upregulation of RGS4 expression by IL-1beta in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3beta pathway. Links for ERK1/2, p38MAPK and GSK3beta. (Mus musculus) PubMed

 5230.

Capase-12 seems to be involved in apoptosis induced by ischemia/reperfusion (caspase 12). (Mus musculus) PubMed

 5231.

Gingival fibroblast stimulated the release of TGF-beta1, which in turn inhibited the transcription and synthesis of MMP-7.[MMP-7] (Mus musculus) PubMed

 5232.

PTPro interaction with specific antibodies acutely increases albumin permeability in glomerular podocytes [PTPro]. (Mus musculus) PubMed

 5233.

RANKL protects osteoclasts from the apoptosis-inducing and anti-resorptive effects of bisphosphonates in vitro by incresing the level of Mcl-1 (Mus musculus) PubMed

 5234.

cAMP-dependent regulation of CYP19 gene in rabbit preovulatory granulosa cells and corpus luteum (Mus musculus) PubMed

 5235.

Urban particulate matter caused severe oxidative stress in macrophages from diabetes mellitus rabbits and up-regulation of cytokine expression and MMP-9 activity. (Mus musculus) PubMed

 5236.

In the myocardium, angiotensin 1-7 through its binding to Mas receptor induces a negative inotropic effect modulated by the endocardial endothelium and nitric oxide and independent of AT(1) or AT(2) receptors activation. (Angiotensin 1-7) (Mus musculus) PubMed

 5237.

The aim of this study was to investigate the deleterious effects of shockwaves (SWs) using heat shock protein (HSP) 70 expression on obstructed kidneys with different obstruction periods.[HSP70] (Mus musculus) PubMed

 5238.

The crystal structure of the N-terminal 210 residues of RyR1 (RyR(NTD)) at 2.5 A, is reported.[Ryr1] (Mus musculus) PubMed

 5239.

[I-BABP] Substitution of the helix-turn-helix capping motif of ileal bile acid binding protein (I-BABP) with a flexible Gly-Gly-Ser-Gly linker results in loss of stabilizing hydrophobic contacts and renders the I-BABP beta-clamshell structure unfolded. (Mus musculus) PubMed

 5240.

In this study, a previously cloned beta-glucosidase gene, umbgl3B, was heterologously expressed in Escherichia coli, and the biochemical properties of the purified enzyme were characterized.[umbgl3B] (Mus musculus) PubMed

 5241.

The anti-adhesive property by insulin may be mediated by the Akt-mediated and nitric oxide-dependent pathway.[Akt] (Mus musculus) PubMed

 5242.

Although macrophages were the main source of myeloperoxidase, not all macrophages secreted myeloperoxidase, which suggests that distinct subpopulations contribute differently to atherogenesis [myeloperoxidase]. (Mus musculus) PubMed

 5243.

Data show that both with wild-type glutamate transporter EAAC1 and EAAC1-D455N, not only sodium but also lithium could support radioactive acidic amino acid uptake: [EAAC1] (Mus musculus) PubMed

 5244.

Wnt-5A (upregulated by IL-1beta) may be associated with cartilage destruction by promoting the expression of matrix metalloproteinases [IL-1beta]. (Mus musculus) PubMed

 5245.

These data strongly suggest that nectin-3 may contribute to the identification of corneal epithelial stem cells. (Mus musculus) PubMed

 5246.

CCR2/MCP-1 mediated monocyte recruitment and a low shear environment act synergistically to augment neointimal hyperplasia development.[CCR2] (Mus musculus) PubMed

 5247.

postconditioning neuroprotective effects on the spinal cord are mediated by phosphatidylinositol 3-kinase--PI3 KINASE (Mus musculus) PubMed

 5248.

Results describe the purification and identification of the first L-rhamnose-1-dehydrogenase gene, RHA1, in the yeast Pichia stipitis [RHA1]. (Mus musculus) PubMed

 5249.

purifcation, substrate specificity, and phylogenetic relationship to Azotobacter vinelandii and E Coli bacterial LADH[lactaldehyde dehydrogenase] (Mus musculus) PubMed

 5250.

Zinc finger motifs and basic motifs of p12 protein have a role in subcelular localization, binding to nucleic aicds, and hypersensitive response induction upon expression from a PVX vector. [p12] (Mus musculus) PubMed

 5251.

Erythromycin C-12 hydroxylase (CYP113A1), the P450 cytochrome active in the final stages of erythromycin biosynthesis, was cloned and expressed in E. coli. [EryK} (Mus musculus) PubMed

 5252.

amastigotes and promastigotes both express multiple major surface protease (MSP)isoforms, but these MSPs differ biochemically and localize differently in the two parasite stages.[MSP in strain MHOM/BR/00/1669] (Mus musculus) PubMed

 5253.

First report of cloning, sequencing, expression, and substrate specificity of recombinant cysteine proteinase B. [CPB] (Mus musculus) PubMed

 5254.

results revealed that the virulent strain produced higher amounts of metallopeptidase (gp63) & cysteine peptidase(cpb)molecules, detected both in the surface and cytoplasm regions, than the avirulent counterpart [gp63,cpb] (Mus musculus) PubMed

 5255.

phylogenetic, molecular, and biochemical characteristics of SucB, one of two novel intracellular invertases identified in Aspergillus niger [SucB] (Mus musculus) PubMed

 5256.

The beta-xylosidase activities of the A. brasiliensis and A. niger strains had similar temperature and pH optima at 75 degrees C and pH 5 and retained 62% and 99%, respectively, of these activities over 1 h at 60 degrees C [beta-xylosidase] (Mus musculus) PubMed

 5257.

A new GH12 (glycosyl hydrolase 12) family XEG, AnXEG12A, was overexpressed, purified and characterized [xyloglucan-specific endo-beta-1,4-glucanase, AnXEG12A] (Mus musculus) PubMed

 5258.

Solution of these structures will help shed light on the molecular determinants of improved activity and high enantioselectivity towards a broad range of substrates[monoamine oxidase] (Mus musculus) PubMed

 5259.

suggest that glucoamylase functions via transient dimer formation during hydrolysis of insoluble substrates and address the question of the cooperative effect of starch binding and hydrolysis[glucoamylase] (Mus musculus) PubMed

 5260.

The molecular weight of the subunit was determined to be 76 kDa and the pI = 4.8. [NAGA] (Mus musculus) PubMed

 5261.

An in-depth characterization of the Aspergillus niger glucoamylase (glaA) promoter performance was carried out on defined medium.[glaA] (Mus musculus) PubMed

 5262.

amino acids of PGI and PGII that are unique in binding the pectin backbone and that are identified as possibly crucial for specificity [PGI & PGII] (Mus musculus) PubMed

 5263.

The finding that A. niger does not thrive on nicotinamide as a sole carbon source suggest that the fungal dimethylmalate lyase functions in a presently unknown metabolic pathway.[dimethylmalate lyase in strain N400] (Mus musculus) PubMed

 5264.

During secretion stress, hacA transcription starts from a new start site closer to the ATG and relieves the mRNA from the translational block. [HacA] (Mus musculus) PubMed

 5265.

Under the conditions of citric acid production alternative oxidase of Aspergillus niger is regulated at the transcription stage.(aox1) (Mus musculus) PubMed

 5266.

substrate specificity of a GH12 xyloglucanase from Aspergillus niger [XEG12A] (Mus musculus) PubMed

 5267.

Metabolic pathways that are not directly involved in acetate metabolism are influenced by acuB deletion. [acuB] (Mus musculus) PubMed

 5268.

Aglu gene contained 2880 bp and encoded a protein of 960 amino acids. [Aglu] (Mus musculus) PubMed

 5269.

The A. terreus NADP-GDH was more stable and showed non-competitive ammonium inhibition with respect to glutamate compared to A. niger NADP-GDH. [NADP-GDH] (Mus musculus) PubMed

 5270.

The optimal substrate of lipB is 4-nitrophenyl octanoate and the optimal temperature is 50 degrees C. [LipB] (Mus musculus) PubMed

 5271.

het-c has no direct function in heterokaryon incompatibility in A. niger because the necessary allelic variation is absent. [het-c] (Mus musculus) PubMed

 5272.

A single amino acid change in L-arabitol dehydrogenase contributes significantly to the substrate specificity difference between LAD and xylitol dehydrogenase. [LadA] (Mus musculus) PubMed

 5273.

Disruption of fruR, which is a deoxyribonucleoside repressor (DeoR)-type transcriptional regulator co-transcribed with ptsF, resulted in enhanced induction of the fructose-pts operon, ptsI, and ptsH expression in response to fructose.[FruR] (Mus musculus) PubMed

 5274.

These results suggest that SugR represses ptsI and ptsH in the absence of PTS sugar and derepression is the mechanism for the induction of the general components of PTS.[SugR] (Mus musculus) PubMed

 5275.

narKGHJI operon is repressed by the ArnR protein under aerobic conditions, whereas the expression of the arnR gene is autoinduced by ArnR. (Mus musculus) PubMed

 5276.

DcsT gene is a transporter involved in the utilization of C4 dicarboxylates in C. glutamicum. [dcsT] (Mus musculus) PubMed

 5277.

These assays revealed that SugR acts as a negative transcriptional regulator of the gapA gene in the absence of sugar, and repression by SugR is alleviated in the presence of sugar...[SugR] (Mus musculus) PubMed

 5278.

IdhA is repressed by SugR in the absence of sugar. [IdhA. SugR] (Mus musculus) PubMed

 5279.

B2 upregulates Bax and triggers mitochondria-mediated necrotic cell death independent of cytochrome c release [non-structural protein B2] (Mus musculus) PubMed

 5280.

The coding region of the inulinase contained 514 amino acids with a calculated molecular mass of 58.04 kDa. [INU1] (Mus musculus) PubMed

 5281.

Deletion analyses indicated that aer-2 actively mediates an aerotaxis response, as assayed in succinate soft agar plates as well as a capillary assay. [aer-2] (Mus musculus) PubMed

 5282.

A model derived for the 3-dimensional structure of the molecule indicates that subunits exist in 2 distinct conformations in the tetramer, leading to different relative accessibilities of cysteine and tryptophan residues, as observed in solution.[HlyT] (Mus musculus) PubMed

 5283.

The conserved aspartate residue in the transmembrane helix of PomB and its H(+)-dependent homologs might act as a ligand for the coupling cation in the flagellar motor.[PomB] (Mus musculus) PubMed

 5284.

all the designated DDD aspartates reside in clusters of amino acids that are conserved among piggyBac family transposase members. All four aspartates are necessary for excision to occur in a cellular environment[piggyBac, accession # J04364] (Mus musculus) PubMed

 5285.

These results suggested that the mechanism of the proteolysis by the wild-type norovirus 3C-like protease was different from that of typical chymotrypsin-like serine proteases (Mus musculus) PubMed

 5286.

Developed sandwich enzyme immunoassay to accurately quantify neurotoxin A, whatever the neurotoxin form. (Mus musculus) PubMed

 5287.

The binding sites for gangliosides and phosphatidylethanolamine were identified in BoNT/C and BoNT/D. [BoNT/C, BoNT/D] (Mus musculus) PubMed

 5288.

Seven wild-type and ARTT loop-mutant structures of C3 exoenzyme of Clostridium botulinum free and bound to its true substrate, NAD, were presented. (C3 exoenzyme) (Mus musculus) PubMed

 5289.

C3 protein induces a proinflammatory response in microglia resembling the classical proinflammatory phenotype elicited by bacterial lipopolysaccharide. [Clostridium botulinum exoenzyme C3] (Mus musculus) PubMed

 5290.

The authors that the long-lived nature of C2I in the host cell cytosol was essential for the nonreversible cytotoxic effect of C2 toxin, resulting in delayed apoptosis of the tested mammalian cells.[C2I] (Mus musculus) PubMed

 5291.

A protease was purified from the culture medium of Clostridium botulinum serotype C strain Stockholm. (GenBank Accession No. AB325802) (Mus musculus) PubMed

 5292.

the crystal structure of BoNT E holotoxin and show that the domain association is different and unique, although the individual domains are similar to those of BoNTs A and B (Mus musculus) PubMed

 5293.

The crystallization and preliminary X-ray diffraction analysis to near-atomic resolution of DHDPS from Clostridium botulinum crystallized in the presence of its substrate pyruvate are presented.[DHDPS] (Mus musculus) PubMed

 5294.

BLIP surface is tolerant of substitutions in residues that contact TEM-1 beta-lactamase in the structure of the complex[TEM-1 beta-lactamase] (Mus musculus) PubMed

 5295.

5'UTR was responsible for a low reporter gene expression, whereas the intergenic region (IR) between LORIEN and MAT2 genes provided high luc levels[LORIEN and MAT2] (Mus musculus) PubMed

 5296.

LiSIR2RP1 is an NAD(+)-dependent deacetylase that also exerts an ADP-ribosyltransferase activity. (Mus musculus) PubMed

 5297.

Lack of HSP70-II expression has a pleiotropic effect, influencing cell morphology, replication and virulence. [HSP-70II] (Mus musculus) PubMed

 5298.

Under the pressure of a death stimulus, EndoG is released from mitochondrion and translocates to the nucleus. [EndoG] (Mus musculus) PubMed

 5299.

causes platelet aggregation in a complement- or fibrinogen-dependent manner. [ClfB] (Mus musculus) PubMed

 5300.

strains with N-terminal truncations in SrrA displayed defects in growth and abnormally upregulated virulence factor expression under low-oxygen conditions.[SrrA] (Mus musculus) PubMed

 5301.

MazFSa cleaves single-strand RNA preferentially at the 5' side of the first U or 3' side of the second U residue within the consensus sequences VUUV' (where V and V' are A, C, or G and may or may not be identical).[MazF] (Mus musculus) PubMed

 5302.

ica operon is required for the expression of the important multifunctional virulence determinants eap and emp [Emp] (Mus musculus) PubMed

 5303.

The activation of CD14(+) cells by Eap suggests that it could play a significant role in both septic shock and fever, two of the major pathological features of S. aureus infections.[Eap] (Mus musculus) PubMed

 5304.

alpha-haemolysin in an agrA mutant background is required for vesicular escape of S. aureus into the host cell cytosol. (alpha-haemolysin) (Mus musculus) PubMed

 5305.

clumping factor A (ClfA) was identified as a specific protein bound by factor I; the shed ClfA fragment increased factor I cleavage of C3b into inactive C3b (Mus musculus) PubMed

 5306.

SarZ is a functional homologue of MgrA that senses oxidative stress and coordinates the expression of genes involved in metabolic switching, antibiotic resistance, peroxide stress defence, virulence, and cell wall properties. [SarZ] (Mus musculus) PubMed

 5307.

These findings suggest that fudoh in the SCCmec type-II region suppresses colony spreading and exotoxin production, and is involved in S. aureus pathogenesis.[Fudoh] (Mus musculus) PubMed

 5308.

MgrA acts as an activator of SarZ,which has an important role in controlling regulatory and virulence gene expression in S. aureus. [MgrA, SarZ] (Mus musculus) PubMed

 5309.

Ectopic expression of MazF led to a rapid decrease in growth but cells remained viable.[MazF] (Mus musculus) PubMed

 5310.

Thus, IsdA is an important adhesin to human ligands, which predominate in its primary ecological niche.[IsdA] (Mus musculus) PubMed

 5311.

CymR controls utilization of sulfur sources of human origin such as taurine and homocysteine and is required for efficient biofilm formation. [CymR] (Mus musculus) PubMed

 5312.

study found recognition specificity resides in pepper Bs3 promoter & is determined by binding of AvrBs3 to promoter region; data suggest recognition mechanism in which Avr protein binds & activates the promoter of the cognate R gene [AvrBs3] (Mus musculus) PubMed

 5313.

AvrBs3 binds to a conserved element in the Capsicum annuum upa20 promoter & induces gene expression through its activation domain; AvrBs3 provokes developmental reprogramming of host cells by mimicking eukaryotic transcription factors [AvrBs3] (Mus musculus) PubMed

 5314.

SRE1, a gene encoding a GATA-type protein, bound to promoter sequences of genes involved in siderophore biosynthesis [Sre1] (Mus musculus) PubMed

 5315.

The cloned FPPS gene carries an open reading frame of 1044-bp encoding a deduced protein of 347 amino acids with a molecular weight of 39.83 kDa, and the coding region is interrupted with a 63-bp intron [Botrytis cinerea: Farnesyl pyphosphate synthase] (Mus musculus) PubMed

 5316.

BcatrA reduced sensitivity to cycloheximide and catechol, indicating that BcatrA product functions as a multidrug transporter.[BcatrA] (Mus musculus) PubMed

 5317.

although IE86 does repress the UL144-mediated activation of a synthetic NFkB promoter, it is unable to block UL144-mediated activation of the CCL22 promoter, and this lack of responsiveness to IE86 appears to be regulated by binding of CREB.[viral IE86] (Mus musculus) PubMed

 5318.

UL112-113 locus was able to activate the complete KSHV lytic cycle, while the UL122-123 locus, encoding the IE1 and IE2 proteins, known to be strong transactivators, did not[UL113] (Mus musculus) PubMed

 5319.

These data suggest a specific pUL69-pUL97 interaction and pUL97-mediated phosphorylation which influences the regulatory activities of pUL69. [UL69] (Mus musculus) PubMed

 5320.

study demonstrates that miR-UL112 targets the UL114 gene; also show that two additional HCMV-encoded miRNAs, miR-US25-1 and miR-US25-2, reduce viral replication & DNA synthesis [miR-UL112, miR-US25-1, miR-US25-2] (Mus musculus) PubMed

 5321.

production, purification, and physicochemical and biochemical characterizations of a new extracellular alpha-amylolytic enzyme, ScAmy43[ScAmy43] (Mus musculus) PubMed

 5322.

BGT1 was up-regulated during infection of Brassica napus leaves. [BGT1] (Mus musculus) PubMed

 5323.

Sclerotinia sclerotiorum PG interacts with canola IPG-1 protein during early infection. [PG] (Mus musculus) PubMed

 5324.

This is the first study to describe nucleotide and amino acid sequences of serine hydroxymethyltransferase (SHMT) from the malaria parasite Plasmodium vivax. [SHMT] (Mus musculus) PubMed

 5325.

Results suggested that almost all of the observed polymorphisms were located at one surface of apical membrane antigen 1 (apical membrane antigen 1). (Mus musculus) PubMed

 5326.

Crystal structures of Plasmodium vivax ADA in complex with adenosine, guanosine, and the picomolar inhibitor 2'-deoxycoformycin, are reported.[Adenosine deaminase] (Mus musculus) PubMed

 5327.

This study describes the identification and characterisation of Pv38, based on the available genomic sequence of Plasmodium vivax and previous studies done with its Plasmodium falciparum homologue: Pf38. (Pv38) (Mus musculus) PubMed

 5328.

Amplification of pvmdr1 and single-nucleotide polymorphisms are correlated with susceptibility of P. vivax to multiple antimalarial drugs [mdr1] (Mus musculus) PubMed

 5329.

Pv41 transcription and expression during late intra-erythrocytic parasite stages were demonstrated and its subcellular localization on the parasite surface was defined. (Pv41) (Mus musculus) PubMed

 5330.

frequency distribution of mutations associated with sulphadoxine-pyrimethamine resistance was investigated in pvdhfr and pvdhps genes from field isolates [dhfr and dhps] (Mus musculus) PubMed

 5331.

first report of the region between interspecies conserved blocks 4 and 5 of the MSP-1 gene of P. vivax in South Korea [MSP-1] (Mus musculus) PubMed

 5332.

the equilibrium unfolding, functional activity regulation and stability characteristics of Glutathione S-transferases of Plasmodium vivax [Glutathione S-transferases] (Mus musculus) PubMed

 5333.

The crystal structure of PNP (purine nucleoside phosphorylase) is described and is seen to have many features in common with the previously reported structure of PNP. (PNP). (Mus musculus) PubMed

 5334.

Conserved cysteine residues in NqrD and NqrE subunits are necessary for the correct folding and/or the stability of the NADH:quinone oxidoreductase complex (NqrD and NqrH). (Mus musculus) PubMed

 5335.

Study used mutagenesis and suppressor analyses to identify the acyl-homoserine lactone(AHL)-binding domain of LuxN and discovered LuxN mutants that confer both decreased and increased AHL sensitivity.[LuxN] (Mus musculus) PubMed

 5336.

Enzymatic analyses demonstrated that the recombinant DegQVh protein expressed in and purified from E. coli was an active serine protease whose activity required the integrity of the catalytic site and the PDZ domains.[DegQ in strain HH2] (Mus musculus) PubMed

 5337.

C92, C95, and C-terminal 12 of FurVh proved to be functionally inessential. [Fur] (Mus musculus) PubMed

 5338.

The crystal structure of V. harveyi luciferase bound to flavin mononucleotide (FMN)was determined, revealing a single contact between Phe272 of the alpha subunit and Tyr151 of the beta subunit, essential for activity. (luciferase alpha and beta subunit). (Mus musculus) PubMed

 5339.

The crystal structure of GcnA, an N-acetyl-beta-D-glucosaminidase from Streptococcus gordonii, was solved by multiple wavelength anomalous dispersion phasing using crystals of selenomethionine-substituted protein.[GcnA] (Mus musculus) PubMed

 5340.

These findings indicate that S. gordonii Hsa specifically binds to GPA and band 3, alpha2-3-linked sialic acid membrane glycoproteins.[Hsa in strain Challis DL1] (Mus musculus) PubMed

 5341.

These results suggest that, in S. gordonii, mutations in glmM appear to influence bacterial cell growth and morphology, biofilm formation, and sensitivity to penicillins.[GlmM in strain DL1] (Mus musculus) PubMed

 5342.

Mfa1-interacting interface of sspB antigen encompasses both the KKVQDLLKK and NITVK motif and suggest that the adherence of P. gingivalis to streptococci is driven by a protein-protein interaction domain as in the eukaryotic NR box. [sspB] (Mus musculus) PubMed

 5343.

Platelet binding by GspB is a major interaction in the pathogenesis of endocarditis.[GspB] (Mus musculus) PubMed

 5344.

These data suggest that S. gordonii DL1 Hsa specifically binds to three glycoproteins as receptors and that this interaction may be the initial bacterial binding step in infective endocarditis by oral streptococci.[Hsa in strain DL1] (Mus musculus) PubMed

 5345.

These data suggest that S. gordonii BfrAB controls biofilm formation by regulating multiple ABC-transporter systems. [BfrA, BfrB] (Mus musculus) PubMed

 5346.

GlmM contributes to the resistance to polymorphonuclear leukocytedependent killing. (Mus musculus) PubMed

 5347.

SspB was crystallized using the hanging-drop vapour-diffusion method and X-ray data were collected and processed to a maximum resolution of 2.1 A with 96.4% completeness.[SspB] (Mus musculus) PubMed

 5348.

X-ray diffraction data were collected from betaC-S lyases from two oral bacteria, Streptococcus anginosus and S. gordonii.[betaC-S lyase] (Mus musculus) PubMed

 5349.

In medaka, dmrt I bY mediates a mitotic arrest of PGCs in males prior to testes differentiation at the sex determination stage. This occurs possibly via a cross-talk of Sertoli cells and PGCs (Mus musculus) PubMed

 5350.

mRNA levels increased after temperature shift from 25 to 15 degrees C in 3 h, and then decreased rapidly to near the original level within 12 h. [CYR61] (Mus musculus) PubMed

 5351.

Data show that high temperature induced DMRT1 expression in genotypic females, which was observed already from stage 36 [DMRT1] (Mus musculus) PubMed

 5352.

Dmrt1a is exclusively expressed in adult testes, 50 times higher than dmrt1bY [dmrt1a; dmrt1bY] (Mus musculus) PubMed

 5353.

Both Pax1 and Pax9 are indispensable for the development of the vertebral body and neural arch. (Pax1, Pax9) (Mus musculus) PubMed

 5354.

primordial germ cell movements are shown to be the consequence of a combination of active SDF1a & SDF1b-guided migration; both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs[SDF1b] (Mus musculus) PubMed

 5355.

The medaka fabp7 gene consists of four exons in approximately 1 kb of the genomic region with a deduced amino acid sequence that exhibits over 80% identity with those of other higher vertebrates [fabp7] (Mus musculus) PubMed

 5356.

cxcr7-expressing somitic domain expanded posteriorly with its margin immediately anterior of posteriorly drifting PGCs, as if PGCs were thrusted toward the gonadal area[CSCR7] (Mus musculus) PubMed

 5357.

Comparative expression analyses showed medaka hoxa2a and b2a expression in the 2nd pharyngeal arch (PA2) beyond the onset of chondrogenesis, which suggests these genes function redundantly as selector genes of PA2 identity[hoxa2a and b2a] (Mus musculus) PubMed

 5358.

study identified abcb7 as the responsible gene for the nmk mutant with fatty liver; findings suggest novel roles of Abcb7 in the development of physiologically functional liver [abcb7] (Mus musculus) PubMed

 5359.

CHD5 was expressed in the developing heart after stage 28. It was also detected in the developing heart at embryonic stages 28 & 35. Knocking-down of CHD5 function caused severe cardiac & ocular abnormalities. CHD5. (Mus musculus) PubMed

 5360.

beta4GalT2 activity is cell-autonomously required in cells undergoing mediolateral cell intercalation, which drives extension movements during medaka gastrulation.[beta4GalT2] (Mus musculus) PubMed

 5361.

results point to an important role of olSfrp5 in visual system formation and indicate that olSfrp1 and olSfrp5, despite their overlapping expression, have only partially redundant function during eye development [Sfrp5] (Mus musculus) PubMed

 5362.

Lack of SeqA causes attenuation of S. enterica virulence by the oral route but not by the intraperitoneal route, suggesting a virulence defect in the intestinal stage of infection [SeqA] (Mus musculus) PubMed

 5363.

These results suggest that the N-terminal region of WbaP, which contains four transmembrane domains, is essential for the insertion or stability of the protein in the bacterial membrane.[WbaP] (Mus musculus) PubMed

 5364.

mutations in ramR appear to play a major role in the efflux-mediated multidrug resistance phenotype of serovar Typhimurium [ramR] (Mus musculus) PubMed

 5365.

confirmed the 12-transmembrane segments topology for this Wzx, and also indicated that the C-terminus was located within the cytoplasm [serovar Typhimurium Group B, gene=Wzx] (Mus musculus) PubMed

 5366.

PagN is an outer membrane protein that is a haemagglutinin and contributes to adherence to mammalian cells [PagN] (Mus musculus) PubMed

 5367.

conformational dynamics of O-Acetylserine sulfhydrylase [OASS] (Mus musculus) PubMed

 5368.

All four extracellular loops of PagN are crucial for invasion of mammalian cells. [PagN] (Mus musculus) PubMed

 5369.

preliminary X-ray characterization of a glycerol dehydrogenase [GldA] (Mus musculus) PubMed

 5370.

crystal structure of AdiC at 3.2 A resolution [AdiC] (Mus musculus) PubMed

 5371.

Integration of Wnt-dependent and Wnt-independent cell fate specification pathways within the Caenorhabditis genus can occur in different ways.[SKN-1, POP-1] (Mus musculus) PubMed

 5372.

data indicate that NIT2 is a central regulatory gene required for nitrate signaling on the Chlamydomonas NIA1 gene promoter and that intracellular nitrate is needed for NIT2 function and to modulate NIA1 transcript levels [NIT2] (Mus musculus) PubMed

 5373.

Gsm1/Gsp1 dyads share sequence homology with and are functionally related to KNOX/BELL dyads regulating stem-cell (meristem) specification in land plants.[Gsm1] (Mus musculus) PubMed

 5374.

ODA16 appears to function as a cargo-specific adaptor between IFT particles and outer row dynein needed for efficient dynein transport into the flagellar compartment.[ODA16] (Mus musculus) PubMed

 5375.

This gene was first identified in a medaka mutant, and found to be mutated in primary ciliary dyskinesia patients from two affected families as well as in the pf13 mutant of Chlamydomonas [pf13] (Mus musculus) PubMed

 5376.

Sporangin is synthesized at a specific stage of the Chlamydomonas cell cycle and localized to the flagella of daughter cells within the sporangial cell wall. [sporangin] (Mus musculus) PubMed

 5377.

Chlamydomonas kinesin-13 (CrKinesin-13), a member of the kinesin-13 family of microtubule depolymerizing kinesins best known for their roles in the cell cycle, functions in flagellar disassembly and flagellar assembly.[kinesin-13] (Mus musculus) PubMed

 5378.

In microtubule sliding assays, using axonemes containing I1 dynein but devoid of IC97, show reduced microtubule sliding velocities, revealing a critical role for IC97 in I1-dynein function and dynein-driven motility: [IC97] (Mus musculus) PubMed

 5379.

A [4Fe-4S] cluster is present in the iron hydrogenase HydA and is required for in vitro activation by the HydE, HydF, and HydG maturation enzymes. (HydA). (Mus musculus) PubMed

 5380.

It was concluded that REP27 plays a dual role in the regulation of D1 protein turnover by facilitating cotranslational biosynthesis insertion and activation of the nascent D1 during the photosystem II repair process. (Mus musculus) PubMed

 5381.

PGRL1 in C. reinhardtii may possess a dual function in the chloroplast; that is, iron sensing and modulation of electron transfer [PGRL1] (Mus musculus) PubMed

 5382.

We cloned cDNA and determined the amino acid sequence of MB7TM2 receptor. [MB7TM2] (Mus musculus) PubMed

 5383.

we report a first rainbow trout NILT sequence, Onmy-NILT2D, alternatively spliced into a long membrane-bound and a short, putatively secreted form, both with the same two immunoglobulin (Ig)-like domains. [Onmy-NILT2D] (Mus musculus) PubMed

 5384.

RTLL is a group VII C-type lectin with multiple isoforms that bind pathogen-associated molecular patterns such as chitin and microbial surface (Mus musculus) PubMed

 5385.

in response to a viral hemorrhagic septicemia virus (VHSV) infection, the levels of expression of IL-8R are suppressed in the head kidney, spleen and muscle, in contrast to what occurs in response to Poly I:C [interleukin-8 receptor ] (Mus musculus) PubMed

 5386.

Gb3 plays a role in innate immunity by cooperating with natural ligands, L-rhamnose-binding lectins[Gb3] (Mus musculus) PubMed

 5387.

the cloning and characterization of the CR3 receptor beta2 (CD18) and aM (CD11b) subunits in rainbow trout [CR3 receptor] (Mus musculus) PubMed

 5388.

carnitine palmitoyltransferase (Mus musculus) PubMed

 5389.

In tissue from infected rainbow trout, there was an overall relative increase in ladderlectin compared to healthy fish and proteins were detected in extra-cellular spaces surrounding bacteria, fungi and protozoa [ladderlectin] (Mus musculus) PubMed

 5390.

Genetic selection for muscle fat content in trout results in overactivation of the TOR signaling pathway-associated lipogenesis and probably also improves utilization of glucose [TOR]. (Mus musculus) PubMed

 5391.

TNF-alpha1 is 1379 bp and consists of a 738 bp open reading frame (ORF) translating into a predicted protein of 246 amino acids. TNF-alpha2 is 1412 bp containing an ORF and translated protein the same lengths as TNF-alpha1 [TNF-alpha1 and TNF-alpha2] (Mus musculus) PubMed

 5392.

The complete T-cell receptor alpha/delta locus of Atlantic salmon (Salmo salar) has been characterized and annotated. The genomic and expression data suggest that the salmon T-cell receptor has enormous capacity to recognize a wide diversity of antigens. (Mus musculus) PubMed

 5393.

selection is playing a role in shaping diversity at the lysyl oxidase gene locus (Mus musculus) PubMed

 5394.

glycosylation is not required for IFN-alpha2 antiviral activity [IFN-alpha2] (Mus musculus) PubMed

 5395.

identified two closely related Tollip-encoding genes in Atlantic salmon (Salmo salar) Tollip II (Mus musculus) PubMed

 5396.

the homologues of mammalian CD4 in Atlantic salmon (Salmo salar): CD4-1 with four extracellular domains and CD4-2a and CD4-2b with two extracellular domains [CD4-1 and CD4-2] (Mus musculus) PubMed

 5397.

study found that loss of RAD51 function in the moss Physcomitrella patens caused a significant vegetative phenotype, indicating an important function for RAD51 in this organism [RAD51] (Mus musculus) PubMed

 5398.

PprecA2 partially complemented the recA mutation in Escherichia coli and was involved in the repair of chloroplast DNA in Physcomitrella patens [PprecA2] (Mus musculus) PubMed

 5399.

DCL3is required for the accumulation of 22-24 nucleotide(nt) small interfering RNAs(siRNA), but not 21 nt siRNAs. [Dcl3] (Mus musculus) PubMed

 5400.

Data show that the K(m) values for beta-sitosterol of CYP710A13 and CYP710A14 were at comparable levels of those reported with higher plant CYP710A proteins: [CYP710A13 and CYP710A14] (Mus musculus) PubMed

 5401.

RECA1 does not promote but rather suppresses recombination among short repeats scattered throughout the mitochondrial genome, thereby maintaining mitochondrial genome stability. (Mus musculus) PubMed

 5402.

OLE1, OLE2, and OLE3 are expressed in a tissue specific manner, which can be altered via alternative splicing. [3 genes] (Mus musculus) PubMed

 5403.

Plants lacking class II formins (For2) are severely stunted and composed of spherical cells with disrupted actin organization.[Formin-2] (Mus musculus) PubMed

 5404.

The chitin-binding domain of chitinase A contributes to the hydrolysis of chitin in the cell-wall of S. commune.[chitinase A] (Mus musculus) PubMed

 5405.

A. nidulans and A. oryzae kexB disruptants grown under hyperosmotic conditions processed a recombinant fusion protein [KexB] (Mus musculus) PubMed

 5406.

The apparent K(m) and V(max) values of the enzyme for C12-NBD-ceramide were 3.32 microM and 0.085 micromol min(-1) mg(-1), respectively.[neutral ceramidase] (Mus musculus) PubMed

 5407.

A Coprinopsis cinerea homokaryotic fruiting strain was mutagenised, identifying a mutant that exhibited a hyphal growth temperature sensitive defect and hyphal knot development defect at an early fruiting stage.[Smc1] (Mus musculus) PubMed

 5408.

Coprinus cinereus rad50 mutants reveal an essential structural role for Rad50 in axial element and synaptonemal complex formation, homolog pairing and meiotic recombination (Mus musculus) PubMed

 5409.

IraM (inhibitor of RssB activity during Magnesium starvation) and IraD (inhibitor of RssB activity after DNA damage) inhibit sigmaS proteolysis both in vivo and in vitro.[IraM and IraD] (Mus musculus) PubMed

 5410.

both WfaP and WfgD are forms of UDP-Glc: GlcNAc-pyrophosphate-lipid beta-1,3-glucosyltransferases.[WfaP, WfgD] (Mus musculus) PubMed

 5411.

The investigations performed showed that type II secretion in E. coli Dr+ strains leads to DraD translocation at the bacterial cell surfaces. (Mus musculus) PubMed

 5412.

Overall, efficient glucosylation (IroB), transport (IroC and IroN), and processing (IroD and IroE) of salmochelins are required for avian pathogenic Escherichia coli (APEC) virulence, although IroE appears to serve an ancillary role. (Mus musculus) PubMed

 5413.

These data show for the first time the efficient delivery of the autotransporter EspC protein inside the epithelial cells by EPEC, through cooperation between T5SS and T3SS. (Mus musculus) PubMed

 5414.

Differences in fibronectin binding of almost 2 orders of magnitude were observed between EAEC 042 and a mutant in the AAF/II major pilin gene, aafA.[AafA] (Mus musculus) PubMed

 5415.

The authors show that Cif induces not only G2, but also G1 cell cycle arrest depending on the stage of cells in the cell cycle during the infection. (Mus musculus) PubMed

 5416.

EspC, a Per-activated serine protease autotransporter protein, conferred enhanced resistance on nonpathogenic E. coli.[EspC] (Mus musculus) PubMed

 5417.

A new macrolide efflux protein, Mef(B), with 38% amino acid identity to Mef(A), has been characterized and represents the second member of the mef family of genes.[MefB] (Mus musculus) PubMed

 5418.

We have identified a novel immunodominant cDNA clone, BmL3-helicase, encoding DEAD box RNA helicase by immunoscreening of a larval stage cDNA library of Brugia malayi. [BmL3- RNA helicase] (Mus musculus) PubMed

 5419.

Cytoplasmic NAD-dependent polypropylene glycol dehydrogenase from Stenotrophomonas maltophilia was purified and characterized.[PPG-DH] (Mus musculus) PubMed

 5420.

results indicate that L2 beta-lactamase charge variants give S. maltophilia a better chance of adapting and surviving in response to changes in the environment[L2] (Mus musculus) PubMed

 5421.

These studies demonstrate that the Zn(2) site in L1 is very flexible and can accommodate a number of different transition metal ions.[ L1 metallo-beta-lactamase] (Mus musculus) PubMed

 5422.

Phase combination plus density modification gave an interpretable map. Molecular replacement with a distantly related model foundd a dimer in the asymmetric unit & provided the correct transformation for averaging electron density between SgrAI subunits. (Mus musculus) PubMed

 5423.

Extracellular proteome analysis of the wild-type and DeltaadpA strains revealed that 38 secreted proteins, including many catabolic enzymes, such as protease, glycosyl hydrolase and esterase, were produced in an AdpA-dependent manner.[AdpA] (Mus musculus) PubMed

 5424.

rsmG, but not rpsL, mutants showed greater ability (two- to threefold) to produce streptomycin.[rsmG] (Mus musculus) PubMed

 5425.

The findings indicate that CebR is a master regulator of cellulose/cellooligosaccharide catabolism. [CebR] (Mus musculus) PubMed

 5426.

Constitutive over-expression results in an extended lifespan without impairing vital functions, suggesting a protecting role against oxidative stress. (PaMTH1, a putative methyltransferase) (Mus musculus) PubMed

 5427.

The protein encoded by rpoE gene acted as a sigma factor and was sufficient to direct core RNA polymerase to the rpoE promoter. [rpoE] (Mus musculus) PubMed

 5428.

Flagellar biogenesis requires RpoN2 and FliA and is temporally regulated by FlhA, FlhB, and FlgM.[RpoN2, FliA, FlhA, FlhB, FlgM] (Mus musculus) PubMed

 5429.

Here, we demonstrate that the X. campestris pv. campestris Zur is involved in hypersensitive response (HR) and positively regulates the transcription of hrpA to hrpF operons and hrpX but not hrpG. [Zur] (Mus musculus) PubMed

 5430.

Southern blot analysis of the 47 isolates with ToxA and ToxB probes revealed that the toxin genes were always located on different chromosomes.[ToX, ToxB] (Mus musculus) PubMed

 5431.

SERK1 expression is associated with developmental change. [SERK1] (Mus musculus) PubMed

 5432.

Medicago truncatula has two PISTILLATA homologues with different expression patterns and functions. RNAi silencing of MtPI and MtNGL9 affects floral development. (PI; NGL9) (Mus musculus) PubMed

 5433.

Data conclude that MATE1 is an essential membrane transporter for proanthocyanidin biosynthesis in the Medicago seed coat. [MATE1] (Mus musculus) PubMed

 5434.

Zoocin A has now been determined to be a d-alanyl-l-alanine endopeptidase.[zoocin A] (Mus musculus) PubMed

 5435.

SeE is a novel carboxylesterase with optimal activity for acetyl esters. [SeE] (Mus musculus) PubMed

 5436.

Prophage-encoded hyaluronate lyases play a more direct role in disease pathogenesis. [hyaluronate lyases] (Mus musculus) PubMed

 5437.

Twenty-four S. equi subsp. zooepidemicus strains were analyzed to determine the genetic difference among three previously characterized as zoocin A producers (strains 4881, 9g, and 9h) and the 21 nonproducers.[Zoocin A, Zif] (Mus musculus) PubMed

 5438.

These data show that Zif is a novel FemABX-like immunity factor because it provides resistance to a bacteriolytic endopeptidase by lengthening the peptidoglycan cross bridge.[Zif] (Mus musculus) PubMed

 5439.

Purple acid phosphatase-like sequences in prokaryotic genomes and the characterization of an atypical purple alkaline phosphatase from Burkholderia cenocepacia J2315 (Mus musculus) PubMed

 5440.

expression of E6 increased primary human keratinocytes cell adhesion [HPV16 E6 oncoprotein] (Mus musculus) PubMed

 5441.

UV radiation and wounidng enahnces HPV8 E6 expression and skin tumor development. [HPV8 E6] (Mus musculus) PubMed

 5442.

Later embryos and larvae of amphioxus express AmphiLim1/5 in clusters of cells, probably motoneurons, in the anterior part of the central nervous system, in the hindgut, in Hatschek's right diverticulum [LIM-homeobox gene, AmphiLim1/5] (Mus musculus) PubMed

 5443.

PpNCED1 and VVNCED1 initiate ABA biosynthesis at the beginning of fruit ripening, and that ABA accumulation might play a key role in the regulation of ripeness and senescence of both peach and grape fruits.[VvNCED1] (Mus musculus) PubMed

 5444.

The BTL was expressed during the last maturation stages in both skin and pulp tissues and exhibited an apparent molecular mass of c. 31 kDa. [BTL] (Mus musculus) PubMed

 5445.

Mutants in the rpoE gene that suppress the mutation of the most conserved residue A-30G of the rpoEp3 promoter, were identified.[Sigma E] (Mus musculus) PubMed

 5446.

FliK length variants produce flagellar rods with lengths proportional to the corresponding FliK molecular size, suggesting that FliK controls the length of not only the hook but also the rod. (Mus musculus) PubMed

 5447.

The negative regulatory effect of iron on clyA expression is mainly at translational level. (Mus musculus) PubMed

 5448.

unique dual activity amino acid hydroxylase;TgAaaH1, is constitutively expressed while the other gene, TgAaaH2, is induced during formation of the bradyzoites of the cyst stages of the life cycle [TgAaaH1; TgAaaH2;] (Mus musculus) PubMed

 5449.

Herein, we report the presence of PREX (DNA primase, DNA helicase and DNA polymerase activities), a P. falciparum orthologue in Toxoplasma gondii. [PREX] (Mus musculus) PubMed

 5450.

FtsH1 undergoes processing events to remove both the N- and C-termini. [FtsH1] (Mus musculus) PubMed

 5451.

This study supports for the first time that type 2C protein phosphatase is an important regulator of cell growth in Toxoplasma gondii.[PP2C] (Mus musculus) PubMed

 5452.

Data present a structural model for the inhibition of TgCPL by LHVS and possible roles for TgCPL as a protease involved in the degradation or proteolysis of parasite proteins involved in invasion: [TgCPL] (Mus musculus) PubMed

 5453.

The X-ray structure of the yeast aquaporin Aqy1 from Pichia pastoris at 1.15 A resolution, is presented.[Aqy1] (Mus musculus) PubMed

 5454.

two novel serotonin transporter gene transcripts, SmSERT-A and SmSERT-B, from S.mansoni [SmSERT-A][SmSERT-B] (Mus musculus) PubMed

 5455.

eIF4E binds to m(7)G and m(2,2,7)G caps with similar specificity. [eIF4E] (Mus musculus) PubMed

 5456.

On the Na(+)-driven flagellar motor of Vibrio alginolyticus, FliG copurified with the basal bodies. Data detect FliG on the MS ring surface of the basal bodies. [FliG] (Mus musculus) PubMed

 5457.

PF-8 forms a head-to-head dimer in the form of a C clamp, with its concave face containing a number of basic residues that are predicted to be important for DNA binding.[PF-8] (Mus musculus) PubMed

 5458.

Using large-scale cloning analysis on EBV-positive nasopharyngeal carcinoma cells, two novel EBV miRNA, now named miR-BART21 and miR-BART22, were identified (Mus musculus) PubMed

 5459.

Highly purified and immunoreactive intimin has been successfully obtained, which can adhere to the surface of HEp-2 cells. [intimin] (Mus musculus) PubMed

 5460.

Data discovered that Zur controls a cluster of genes predicted to direct synthesis of an uncharacterized siderophore-related non-ribosomally encoded peptide designated coelibactin. [Zur] (Mus musculus) PubMed

 5461.

WhiD is a soluble protein containing a single [4Fe-4S](2+) cluster ligated by four cysteines. [WhiD] (Mus musculus) PubMed

 5462.

alpha-amylase isoform I-1 degrades starch granules in living rice cells, and Contains a plastid-targeting signal common to both rice and onion cells. [AmyI-1] (Mus musculus) PubMed

 5463.

Overexpression of OsGLK1 promoted transcription of a set of nucleus-encoded genes related to chloroplast functions and plastid-encoded genes. [GLK1] (Mus musculus) PubMed

 5464.

report here the identification and expression analysis of a novel rainbow trout IL-20L molecule that is phylogenetically related to IL-19, IL-20 and IL-24, and its expression is modulated by different cytokines[IL-20-like protein] (Mus musculus) PubMed

 5465.

[Pax6] results show that the strongly conserved features of Pax6 expression through forebrain development shared by all amniote vertebrates are also present in the anamniote amphibians as a common characteristic of the forebrain organization of tetrapods (Mus musculus) PubMed

 5466.

established that methionine sulfoxide reductase A-1 expression decreases during aging and is regulated by the DAF-16/FOXO3a transcription factor.[FOXO3a] (Mus musculus) PubMed

 5467.

The centrosomal localization of Diversin is crucial for its function in Wnt signaling.[Diversin] (Mus musculus) PubMed

 5468.

P-protein undergoes microtubules (MT)-inhibited import, with the mode of MT-interaction being regulated by the oligomeric state of the P-protein.[P-protein] (Mus musculus) PubMed

 5469.

A deletion in the stalk of the NA, a feature observed during the process of adaptation of influenza viruses from wild aquatic birds to poultry, favors viral replication and enhances pathogenesis in chickens. (Mus musculus) PubMed

 5470.

Early gene, hhi1, identified as the gene, or one of the genes, responsible for viral reactivation. [hhi] (Mus musculus) PubMed

 5471.

AAV5 ensures the production of a Rep40-like protein by utilizing a novel internal translation initiation event.[Rep40-like protein] (Mus musculus) PubMed

 5472.

BRITTLE CULM 5 mutants have reduced secondary cell wall thickness in the nodes, and the cell wall composition was specifically altered in the nodes. [bc5] (Mus musculus) PubMed

 5473.

Overexpression of APX in the mitochondria prevents cells from oxidative stress and cellular death. [Apx] (Mus musculus) PubMed

 5474.

GOA31 mutant showed decreased respiration and mitochondrial membrane potential. [Goa1] (Mus musculus) PubMed

 5475.

our results demonstrate that apoptosis of HSV-1-infected iDCs requires both c-FLIP downregulation and diminished expression of viral latency-asociated transcript. (LAT) (Mus musculus) PubMed

 5476.

crystal structure of Escherichia coli FocA at 2.25 A resolution [FocA] (Mus musculus) PubMed

 5477.

FEN1 gene of a model legume, Lotus japonicus, overcomes the lack of NifV in rhizobia for symbiotic nitrogen fixation [fen1] (Mus musculus) PubMed

 5478.

fitness of the npq4 mutant in a shifting light environment is reduced compared to wild-type cells, demonstrating that LHCSR is required for survival in a dynamic light environment [npq4] (Mus musculus) PubMed

 5479.

data indicate that Tipin/Tim1/And1 form a complex that links stabilization of replication fork and establishment of sister chromatid cohesion [And1] (Mus musculus) PubMed

 5480.

Polar transport of indole-3-acetic acid synthesized at the tip region is regulated by ZmPIN1. [PIN1] (Mus musculus) PubMed

 5481.

Data report a diSUMO-like protein that appears to be essential for nuclei segregation and positioning, the prerequisite for cell specification during FG maturation. [DiSUMO-like] (Mus musculus) PubMed

 5482.

OdsH encodes protein localizing to evolutionarily dynamic loci in heterochromatin & leads to decondensation; in male hybrids, D mauritiana OdsH acts as sterilizing factor by associating with heterochromatic Y of D simulans; D simulans OdsH does not [OdsH] (Mus musculus) PubMed

 5483.

[PomA-PomB stator complex] Aspartate24 and at least two other carboxylates constitute sodium ion interaction sites in the PomA-PomB supramolecular motor complex. (Mus musculus) PubMed

 5484.

The structure of TrxR was homodimeric with both NADPH- and flavin adenine dinucleotide (FAD)-binding domains containing variants of the canonical nucleotide binding fold, the Rossmann fold. It can utilize only NADPH for activity. [TrxR] (Mus musculus) PubMed

 5485.

Purified skeletal ryanodine receptors are similarly activated by purified triadin or purified junctin added to their luminal side, although a lack of competition indicated that the proteins act at independent sites.[RyR1] (Mus musculus) PubMed

 5486.

Lsi6 is a silicon transporter responsible for intervascular transfer in the node. [Lsi6] (Mus musculus) PubMed

 5487.

TDR possibly plays crucial regulatory roles in several basic biological processes during rice pollen development.[TDR] (Mus musculus) PubMed

 5488.

revealed intact omTLR7 and omTLR8a1 open reading frames (ORFs) located on chromosome 3 and a second locus on chromosome 22 that contains an omTLR8a2 ORF and a putative TLR7 pseudogene.[TLR7, TLR8a1 and TLR8a2] (Mus musculus) PubMed

 5489.

Rab5 and Rab7 occur on different but partly overlapping endosome populations. Rab7 but not Rab5 occurs on symbiosome membranes. [Rab5; Rab7] (Mus musculus) PubMed

 5490.

Data show that betaine aldehyde dehydrogenase OsBADH1 catalyzes the oxidation of acetaldehyde efficiently, while the activity of OsBADH2 is extremely low: [OsBADH1 and OsBADH2] (Mus musculus) PubMed

 5491.

NeuO expression led to a reduced biofilm formation in biofilm positive E. coli K1 isolates (NeuO). (Mus musculus) PubMed

 5492.

crystal structure of recombinant Lmb, a laminin-binding adhesin from Streptococcus agalactiae, has been determined at 2.5 A resolution.[laminin-binding adhesin] (Mus musculus) PubMed

 5493.

HI-LOX is a chloroplast-localized type 2 13-lipoxygenase gene involved in herbivore-induced jasmonic acid biosynthesis. [HI-LOX] (Mus musculus) PubMed

 5494.

present the catalytic properties and the structure of SH from X. campestris pv. campestris (SC) in the resting apo state with an empty active site (apo SC).[sucrose hydrolase] (Mus musculus) PubMed

 5495.

AMPK signalling in response to mitochondrial dysfunction enhances Legionella proliferation in host cells.[AMPK] (Mus musculus) PubMed

 5496.

BmToll9 is possibly involved in the local gut immune response.[Toll9] (Mus musculus) PubMed

 5497.

the N-terminal domain of Vsr changes its conformation as a result of DNA nicking, and DNA Pol I releases Vsr from the nick by reversing that conformational change [vsr] (Mus musculus) PubMed

 5498.

Resistance to apramycin in these isolates was closely related to aac(3)-IV gene. [aac(3)-IV] (Mus musculus) PubMed

 5499.

The aim of this study was to assess early preconditioning protection against stunning in conscious sheep and analyze the role of ATP-dependent potassium (KATP) channels in the protective mechanism.[mKATP, sKATP] (Mus musculus) PubMed

 5500.

The identification of a mitochondrial-type monothiol glutaredoxin in the mitosomes of G. intestinalis thus completes the mitosomal FeS cluster biosynthetic pathway and provides further evidence for the mitochondrial origin of these organelles. (Mus musculus) PubMed

 5501.

NMR assignment of the FK506-binding domain of PvFKBP35 [FKBP35] (Mus musculus) PubMed

 5502.

OsENOD93-1 is an early nodulin gene expressed in vascular bundles, as well as in epidermis and endodermis. Transgenic plants accumulated higher concentrations of total amino acids and total N in roots. [OsENOD93-1] (Mus musculus) PubMed

 5503.

differences in cry2 mRNA cycling between Ae. aegypti and Cx. quinquefasciatus suggest a potential role for this mammalian-like cryptochrome in the control of mosquito activity patterns[cry2] (Mus musculus) PubMed

 5504.

The OsLRR1 protein interacts with the plasma membrane-localized O. sativa hypersensitive-induced response protein 1. Expression of OsLRR1 in transgenic plants enhances resistance to P. syringae. [OsLRR1; OsHIR1] (Mus musculus) PubMed

 5505.

We demonstrate the interaction of PfeIF4G with PfeIF4E, PfeIF4A (PfH45) and PfPABP. [Eif4G] (Mus musculus) PubMed

 5506.

Data show that an ACE2-Ang-(1-7)-AT(7)R pathway modulates Ang II-dependent ROS formation within the nucleus, providing a protective mechanism against oxidative stress and cell damage: [ACE2 and AT(7)R] (Mus musculus) PubMed

 5507.

(1)H, (15)N, and (13)C assignments for the ferric (low-spin, S = (1/2)) protein with a b heme cofactor and after post-translational modification leading to a c-like heme. [hemoglobin] (Mus musculus) PubMed

 5508.

complete resonance assignment of Plasmodium falciparum thioredoxin in its oxidized form by heteronuclear multidimensional spectroscopy [thioredoxin] (Mus musculus) PubMed

 5509.

NMR assignments for the second microneme adhesive repeat of the microneme protein 3 of E. tenella [MIC3] (Mus musculus) PubMed

 5510.

NMR assignments for cofilin [cofilin] (Mus musculus) PubMed

 5511.

complete NMR chemical shift assignments of Cqui-OBP1 bound to the MOP pheromone obtained at pH 7.0 and 25 degrees C [OBP1] (Mus musculus) PubMed

 5512.

study of changes in ryanodine receptor (RYR) expression and subcellular localization as result of temperature acclimation [ryr] (Mus musculus) PubMed

 5513.

Tbj1, was heterologously expressed, purified, and found to exist as a compact monomer in solution; findings indicated that while Tbj1 did not possess independent chaperone activity, it potentially functioned as a novel co-chaperone of Hsp70 [Tbj1] (Mus musculus) PubMed

 5514.

The characterization of PadA and its interaction with human platelets at the fibrinogen receptor GPIIbIIIa are reported.[PadA] (Mus musculus) PubMed

 5515.

The adrenergic sensors QseC and QseE were not required for norepinephrine (NE)-enhanced enteritis, intestinal colonization of calves, or NE-dependent growth in culture media and did not influence virulence factors.[QseE] (Mus musculus) PubMed

 5516.

A review of of the main functions of DegP and DegS in stress sensing, regulation and protection during the unfolded protein response (DegP and DegS). (Mus musculus) PubMed

 5517.

review summarizes current knowledge about the molecular mechanisms and multiple signal integration in sigma(S)(RpoS) degradation (RpoS). (Mus musculus) PubMed

 5518.

The segmental duplication of Opaque-2 gene is not only found in rice, but also in sorghum, which split from maize 11.9 million years ago.[Opaque-2] (Mus musculus) PubMed

 5519.

These results indicate that OsPBP1 is a novel functional C2-domain phospholipids-binding protein that is required for pollen fertility likely by regulating Ca(2+) and phospholipid signaling pathways.[PBP1] (Mus musculus) PubMed

 5520.

We here describe the sequencing of the gene coding for the PDI from P. chabaudi and analyse the relationship to its counterpart enzymes, particularly with the PDI from other Plasmodium species.[protein disulfide isomerase] (Mus musculus) PubMed

 5521.

no association between low-armour Eda allele and preference for freshwater over saltwater[Ectodysplasin] (Mus musculus) PubMed

 5522.

The segmental duplication of Opaque-2 gene is not only found in rice, but also in sorghum, which split from maize 11.9 million years ago.[Opaque-2] (Mus musculus) PubMed

 5523.

MprF represents a new class of lipid-biosynthetic enzymes with two separable functional domains that synthesize Lys-PG and facilitate Lys-PG translocation.[Staphylococcus aureus SA113, MprF] (Mus musculus) PubMed

 5524.

ICP27 and UL47 jointly displace Paip2 from PABP, and did not alter translation efficiency of transfected reporter RNAs but modulated transcript abundance and expression [ICP27] (Mus musculus) PubMed

 5525.

(1)H, (15)N and (13)C backbone chemical shift assignments for the Psb27 protein of Photosystem II from Synechocystis PCC 6803 [Psb27] (Mus musculus) PubMed

 5526.

Data show that the crystallographic temperature factors for phosphoenolpyruvate sugar phosphotransferase system EI are lower for the HPr binding domain in contact with the P-His domain and higher for EIC: [EI] (Mus musculus) PubMed

 5527.

Data indicate that TvMST has a k(cat)/K(m) for reduced thioredoxin of 6.2 x 10(7) m(-1) s(-1), suggesting that thioredoxin is a preferred substrate for TvMST: [TvMST) (Mus musculus) PubMed

 5528.

The KIF9A and KIF9B genes are strongly associated with the flagellar skeleton and participate in flagellar motility. (Mus musculus) PubMed

 5529.

Thrombospondin-related sporozoite protein (TRSP) is an additional thrombospondin type 1 repeat (TSR)-containing malaria parasite protein that is mainly involved in initial infection of the mammalian host. [TRSP] (Mus musculus) PubMed

 5530.

We report the discovery and characterization of MISFIT, the first protein with paternal effect on the development of the rodent malaria parasite Plasmodium berghei in Anopheles mosquitoes. (Mus musculus) PubMed

 5531.

Identification of a functionally important loop in Salmonella typhimurium ArnT (Mus musculus) PubMed

 5532.

Gamma-glutamylcysteine synthetase has been analysed in the asexual erythrocytic stages of rodent malaria parasite, Plasmodium berghei and its host erythrocytes. [gamma GCS] (Mus musculus) PubMed

 5533.

Bqt3 and Bqt4 are inner nuclear membrane proteins required for chromosomal bouquet formation. [2 genes] (Mus musculus) PubMed

 5534.

OsPra2 protein was localized in the membrane and nucleus of the cell. Overexpression caused a dwarf phenotype. [Pra2] (Mus musculus) PubMed

 5535.

Macrophage inhibitory factor (MIF) expression was induced by oxidized LDL in vascular smooth muscle via a NF-kappaB dependent manner. (Mus musculus) PubMed

 5536.

organization of the T cell receptor beta locus resembles that seen in mammals; there are 51 V segments, a single D segment, 27 Jbeta1 segments, a single Jbeta2 segment, and two constant regions. (Mus musculus) PubMed

 5537.

AphB activates the expression of two virulence regulators, ToxR and TcpP, which together control the expression of the master virulence regulator ToxT. [AphB] (Mus musculus) PubMed

 5538.

Many genes of flavonoid biosynthesis were down-regulated in a tissue-specific manner in M. truncatula lines harboring retrotransposon insertions in the MtWD40-1 gene. [WD40-1] (Mus musculus) PubMed

 5539.

The thermodynamics and kinetics of wild-type and mutant HTLV-1 nucleocapsid/nucleic acid interactions, were quantified.[Nucleocapsid] (Mus musculus) PubMed

 5540.

These results indicate that MutT specifically recognizes 8-oxoguanine nucleotides by the ligand-induced conformational change.[MutT] (Mus musculus) PubMed

 5541.

Transcriptional functionality of duplicated genes, challenging the dogma of mutually exclusive var gene transcription and suggesting mechanisms behind antigenic variation of var2csa genes, is demonstrated.[var2csa] (Mus musculus) PubMed

 5542.

UDP-N-acetylgalactopyranose mutase (UNGM), has relaxed specificity and can use either UDP-Gal or UDP-GalNAc as a substrate.[UNGM] (Mus musculus) PubMed

 5543.

Hatching enzyme space group was assigned as primitive orthorhombic P2(1)2(1)2(1), with unit-cell parameters a = 32.9, b = 62.5, c = 87.4 A. The crystal contained one ZHE1 molecule in the asymmetric unit[ZHE1] (Mus musculus) PubMed

 5544.

(PSD-95)PSD-95 family members at nicotinic synapses on chick ciliary ganglion neurons in culture execute multiple functions to enhance transmission. (Mus musculus) PubMed

 5545.

purification, crystallization & preliminary crystallographic analysis of VanG in complex with ADP are reported. The crystal belonged to space group P3(1)21, with unit-cell parameters a=b=116.1, c=177.2A, & contained 2 molecules in asymmetric unit[VanG] (Mus musculus) PubMed

 5546.

Periconceptional undernutrition and twinning may result in the alterations of placental 11betaHSD1/2 activities at particular times during gestation, influencing fetal hypothalamic-pituitary-adrenal function. (Mus musculus) PubMed

 5547.

Molecular details of the interaction between the semiquinone radical and the nitrate reductase A environment have been provided.[NarG, NarH, NarI] (Mus musculus) PubMed

 5548.

chemical basis for mistranslation of serine for alanine by AlaRS [AlaRS] (Mus musculus) PubMed

 5549.

NMT depletion in trypanosomes causes avirulence and endocytic defects. [NMT] (Mus musculus) PubMed

 5550.

The ICP27 RGG box is unique in its recognition of nucleic acid sequences compared to other RGG box proteins; it prefers flexible, GC-rich substrates that do not form stable secondary structures (ICP27). (Mus musculus) PubMed

 5551.

The 2.95 A resolution X-ray crystal structure of APS kinase reported here revealed a hexameric assembly with D3 symmetry.[APS kinase] (Mus musculus) PubMed

 5552.

show that Tyt1 reconstituted in proteoliposomes is strictly dependent on the Na(+) gradient and is stimulated by an inside negative membrane potential and by an inversely oriented proton gradient. [ Tyt1 ] (Mus musculus) PubMed

 5553.

Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae (Mus musculus) PubMed

 5554.

Partial depletion of ALD and GAPDH was sufficient to rapidly kill the trypanosomes. [ALD, GAPDH] (Mus musculus) PubMed

 5555.

GK3 gene are up-regulated by acclimation to 5 degrees C in diapause eggs. [GK3] (Mus musculus) PubMed

 5556.

CDC16 is one of the key mediators in controlling the overall number of lateral roots and nodules. [CDC16] (Mus musculus) PubMed

 5557.

CYP51 bound to 4 standard fungicides and to 14 XF-synthetic fungicide compounds. [CYP51] (Mus musculus) PubMed

 5558.

Deleterious mutations in the LjRHL1 gene, encoding a basic helix-loop-helix (bHLH) transcription factor, were responsible for the lack of root hairs in the L. japonicus Ljrhl1-1 mutant. [RHL1] (Mus musculus) PubMed

 5559.

Trypanothione reductases from T. brucei and T. cruzi are highly similar based on structural, kinetic and inhibitor studies. [trypanothione reductase] (Mus musculus) PubMed

 5560.

LIN is an E3 ubiquitin ligase containing highly conserved U-box and WD40 repeat domains, and is a regulator of nodulation factor signal transduction pathway. [LIN] (Mus musculus) PubMed

 5561.

The structure of M2 was solved by three different groups, using different techniques, protein sequences and pH environment.[M2] (Mus musculus) PubMed

 5562.

Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition. (Mus musculus) PubMed

 5563.

examined the functions of the non-duplicated KlSir2 and found that it interacts with both KlSir4 and KlSum1.[Sum1] (Mus musculus) PubMed

 5564.

The GTP-binding motif of FlhF is important for polar localization of the flagellum but not for the interaction with FlhG.[FlhF] (Mus musculus) PubMed

 5565.

The results suggested that the assembly characteristics of EcFtsZ and MtbFtsZ are different and indicated that the assembly dynamics of these proteins are regulated by different mechanisms.[FtsZ] (Mus musculus) PubMed

 5566.

Loss of CAP5.5 and CAP5.5V lead to the loss of protein from the posterior cell-end, organelle mis-positioning giving rise to aberrant cytokinesis, and disorganisation of the sub-pellicular microtubules that define trypanosome cell shape.[CAP5.5, CAP5.5V] (Mus musculus) PubMed

 5567.

H94 in the input domain of ArsS is crucial for acid perception in H. pylori 26695 [ArsS] (Mus musculus) PubMed

 5568.

First structural insights into a full-length ROSE element are provided by examining the temperature-induced conformational changes of ROSE(ibpA).[ibpA] (Mus musculus) PubMed

 5569.

The channel-forming capability of recombinant expressed, affinity-purified PorA and PorH proteins of C. glutamicum revealed that the channels consisted solely of these two components. [porH] (Mus musculus) PubMed

 5570.

CadB only acts as a lysine-cadaverine antiporter but also mediates cadaverine uptake at alkaline pH to result in cell protection from superoxide stress. [CadB] (Mus musculus) PubMed

 5571.

Suggest a novel Na(+)/NH(4)(+) exchange pathway in apical membranes of mitochondrion-rich cells of medaka involving slc913, Rhcg1 and Rhbg. (Mus musculus) PubMed

 5572.

These results show that bovine viral diarrhea virus NS4B is an integral membrane protein associated with the Golgi apparatus and virus-induced membranes, the putative site for BVDV genome replication. (Mus musculus) PubMed

 5573.

NS5A protein directly interacts with endogenous beta-catenin and colocalizes with beta-catenin in the cytoplasm. (NS5A protein) (Mus musculus) PubMed

 5574.

The data show that ORF3 is dispensable for Porcine circovirus type 2 replication in pigs.[ORF3] (Mus musculus) PubMed

 5575.

TAR1 mediation of temperature-associated repression of LAC1 suggests a novel mechanism of laccase regulation and a new function for Nmr proteins.[TAR1] (Mus musculus) PubMed

 5576.

Results suggest that TcUBP1 could be linking the mRNA metabolism at both sides of the nuclear pore complex, using the RRM as a nuclear localization signal, and being exported as a cargo on mRNA. (Mus musculus) PubMed

 5577.

RTA expression which controls viral reactivation from latency, was regulated by a virus-encoded microRNA. [RTA] (Mus musculus) PubMed

 5578.

the membrane topology of LolC and LolE proteins [LolC][LolE] (Mus musculus) PubMed

 5579.

Data show that the high-resolution structure of the adenylation domain of Staphylococcus aureus NAD(+)-dependent DNA ligase establishes the conserved domain architecture with other bacterial adenylation domains [ligA] (Mus musculus) PubMed

 5580.

A recombinant His-tagged portion of the extracellular domain of the Staphylococcus aureus serine/threonine kinase Stk1, containing three PASTA subunits, has been crystallized [Stk1]. (Mus musculus) PubMed

 5581.

Results deascribe the expression, purification, crystallization and preliminary X-ray analysis of the NADPH-dependent aldo-keto reductase conjugated polyketone reductase C2 from Candida parapsilosis. (Mus musculus) PubMed

 5582.

The binding of purified GlxR, RamA and RamB was verified by electrophoretic mobility shift assays and the regulatory effects of these proteins on sdhCAB gene expression were tested.[sdhC, RamA, GlxR] (Mus musculus) PubMed

 5583.

We have shown the participation of a novel transcript (named somitovasculin) in circulatory vessel development (Mus musculus) PubMed

 5584.

CATP-5 represents the first P(5)-type ATPase that is associated with the plasma membrane, being expressed in the apical membrane of intestinal cells and the excretory cell. (CATP-5) (Mus musculus) PubMed

 5585.

High frequency oscillatory ventilation combined with exogenous pulmonary surfactant can decrease the concentration of caspase-3 and p73 rabbit with acute respiratory failure. [p73] (Mus musculus) PubMed

 5586.

ZF1 acts as a transcription factor. [ZF1] (Mus musculus) PubMed

 5587.

Expression of protocadherin 9 in the nervous system of the embryonic zebrafish (Mus musculus) PubMed

 5588.

RA68 is required for postmeiotic pollen development. (Mus musculus) PubMed

 5589.

Functional 3c protein expression is crucial for feline coronavirus replication in the gut. [3C] (Mus musculus) PubMed

 5590.

The complex of KfiA and KfiC has polymerase activity to synthesize N-acetylheparosan. [KfiC][KfiA] (Mus musculus) PubMed

 5591.

PpoC from Aspergillus nidulans is a fusion protein with only one active heme (Mus musculus) PubMed

 5592.

Characterization of the restriction enzyme-like endonuclease encoded by the Entamoeba histolytica non-long terminal repeat retrotransposon EhLINE1 (Mus musculus) PubMed

 5593.

the crystal structures of dimeric TftC and tetrameric TftD [TftD][TftC] (Mus musculus) PubMed

 5594.

Alanine aminotransferase of Trypanosoma brucei--a key role in proline metabolism in procyclic life forms (Mus musculus) PubMed

 5595.

Data show that Greatwall is activated during M phase by Cdk1/cyclin B (MPF), but once activated, Gwl promotes PP2A/B55delta inhibition with no further requirement for MPF. (Mus musculus) PubMed

 5596.

GalNAc-P-P-Und is synthesized reversibly by a novel GlcNAc-P-P-Und epimerase after the formation of GlcNAc-P-P-Und by WecA in E. coli O157. [Z3206] (Mus musculus) PubMed

 5597.

Our experimental results at physiological pH and computational analyses reveal that amino acid residues in transmembrane segment II contribute to the cation pathway of NhaA and its pH regulation. [NhaA] (Mus musculus) PubMed

 5598.

analysis of the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I) (Mus musculus) PubMed

 5599.

the first structure of a eukaryotic microsomal 14DM that acts on sterol biosynthesis [sterol 14alpha-demethylase] (Mus musculus) PubMed

 5600.

These results suggest that Rnd1/3 are required for Xenopus somitogenesis. (Rnd1 and Rnd2) (Mus musculus) PubMed

 5601.

fzd6 are broadly expressed throughout the head, during zebrafish craniofacial development (Mus musculus) PubMed

 5602.

ticrr acts in association with TopBP1 and plays an essential role in preinitiation complex formation [ticrr = TopBP1-interacting, checkpoint, and replication regulator] (Mus musculus) PubMed

 5603.

Btbd6a promotes the relocation of Plzf from nucleus to cytoplasm and targets Plzf for ubiquitination and degradation (Mus musculus) PubMed

 5604.

Heparan sulfate functions as a factor that promotes the binding of BAEBL and merozoite invasion. [BAEBL] (Mus musculus) PubMed

 5605.

study reports identification and characterization of an insect farnesol dehydrogenase (AaSDR-1) that oxidizes farnesol into farnesal, a precursor of juvenile hormone , in the corpora allata [farnesol dehydrogenase (AaSDR-1)] (Mus musculus) PubMed

 5606.

The data show that the porcine reproductive and respiratory syndrome E (envelope) protein myristoylation is non-essential for PRRSV infectivity but promotes the growth of the virus. (Mus musculus) PubMed

 5607.

pM140 protects its binding partner, pM141, from ubiquitin-independent proteasomal degradation. Protection is conferred by a stabilization domain mapping to amino acids 306 to 380 within pM140. (pM140 and pM141) (Mus musculus) PubMed

 5608.

These data suggest that PyMIF modulates host immune responses together with host MIF and has potential to prolong parasitemia or the chronicity of malaria infection.[MIF] (Mus musculus) PubMed

 5609.

IDEF1 coordinately regulates the expression of iron deficiency-responsive genes related to iron acquisition and utilization during the early stage of iron deficiency. [IDEF1] (Mus musculus) PubMed

 5610.

[E2 glycoprotein] Sequestering E2 into E7-E2 oligomers provides a possible additional route to uncontrolled E7 expression, in addition and prior to the disruption of the E2 gene during viral integration into the host genome. (Mus musculus) PubMed

 5611.

pre-tRNA binding affinities for Bacillus subtilis and Escherichia coli RNase P are enhanced by sequence-specific contacts between the fourth pre-tRNA nucleotide on the 5' side of the cleavage site and the RNase P protein subunit.[Rnase P] (Mus musculus) PubMed

 5612.

Properties of intragenic suppressor strains lead us to postulate that the C-terminal tail facilitates an oscillation of transmembrane-spanning segment 5 that is required for coordinated pore function and high AmtB activity. [AmtB] (Mus musculus) PubMed

 5613.

A new Plasmodium falciparum erythrocyte binding protein that appears to be located in the micronemes of the merozoite stage of the parasite and membrane linked through a glycosylphosphatidylinositol (GPI) anchor, was identified.[GAMA] (Mus musculus) PubMed

 5614.

TUP1 has pathobiological significance and plays both conserved and distinct roles in serotype A and D strains of C. neoformans.[Tup1] (Mus musculus) PubMed

 5615.

These data establish the direct role of Clp in the response to fluctuating c-di-GMP levels and depict a novel mechanism by which quorum sensing links the second messenger with the X. campestris pv. campestris virulence regulon.[Clp] (Mus musculus) PubMed

 5616.

Protein kinases A and C regulate receptor-mediated increases in cAMP in rabbit erythrocytes [protein kinase A and protein kinase C]. (Mus musculus) PubMed

 5617.

The data suggest that L protein is required for virus growth in J774-1 cells and also suggest that the site responsible for virus growth in those cells, is the acidic domain of L protein. (Mus musculus) PubMed

 5618.

Results identify proteins that are substrate candidates for the DsbA disulfide oxidoreductase as well as being responsible for the virulence attenuation of the dsbA mutant. (Mus musculus) PubMed

 5619.

Data establishes functional groups of genes controlling different regulatory phases, including Ath5 expression at cell-cycle exit and its down-regulation prior to terminal RGC differentiation: [Ath5] (Mus musculus) PubMed

 5620.

genetic evidence that AmtB inactivation depends on the essential protease HflB, which appears to cause inactivation not as a protease but as a chaperone [HflB][AmtB] (Mus musculus) PubMed

 5621.

These results show that SigB may positively influence the appearance of Staphylococcus aureus small-colony variants and the production of biofilm upon aminoglycoside exposure. (Mus musculus) PubMed

 5622.

Recombinant SSL10 inhibited the binding of complement component C1q to IgG-Sepharose and hemolysis of IgG-sensitized sheep erythrocytes via the classical complement activation pathway.[SSl10] (Mus musculus) PubMed

 5623.

most active and enantioselective mutants retain the high thermostability of the parent WT phenylacetone monooxygenase. [Phenylacetone Monooxygenase] (Mus musculus) PubMed

 5624.

Lr10-mediated leaf rust resistance depends on the RGA2 gene. [Lr10; RGA2] (Mus musculus) PubMed

 5625.

Episomal overexpression of EhADH3 in E. histolytica in only subtle increase of virulence in animal models of amebic colitis and amebic liver abscess, making it difficult to directly link EhADH3 levels to virulence.[ADH3] (Mus musculus) PubMed

 5626.

Comparative studies in the cytokine response between Equine infectious anemia virus and its S2 deletion mutant infection revealed that S2 enhances the expression of IL-1alpha, IL-1beta, IL-8, MCP-2, MIP-1beta, IP-10 and IL-34. (Mus musculus) PubMed

 5627.

Data show thaT FLR-2 acts as a signaling molecule for the neural control of intestinal functions, which is achieved in a functional network involving class 1 and class 2 flr genes as well as ghi-1: [ghi-1] (Mus musculus) PubMed

 5628.

Thus, our data suggest that Kv3.1b expression occurs with the onset of functional synaptogenesis, while a different signal, absent from cultures of dissociated auditory brain stem, is needed for Kv1.1 expression.(KV3.1) (Mus musculus) PubMed

 5629.

Phosphate carrier is the phosphate sensor in YMUC and contributes to the structure of this channel.[YMUC] (Mus musculus) PubMed

 5630.

Suggest that urotensin-II normally acts as a pulmonary vasodilator after birth, but in the presence of meconium aspiration syndrome, it assumes a vasoconstrictor role. (Mus musculus) PubMed

 5631.

crystallographic structures of two mutant effector domains, W187Y and W187A, of influenza A/Udorn/72 virus NS1 effector [NS1] (Mus musculus) PubMed

 5632.

Description of a unique PNPase mediated processing pathway for tRNALeu5 that is distinct from all previously reported RNase E and RNase P dependent tRNA processing pathways (leuX). (Mus musculus) PubMed

 5633.

study reports a single nAChR gene (Agamalphabeta9) generating both alpha and non-alpha subunits by alternative splicing [nicotinic acetylcholine receptor, Agamalphabeta9] (Mus musculus) PubMed

 5634.

The endogenous abscissic acid concentration of enf1 was lower than that of wild-type seedlings and the nitrogen fixation activity of abamine-treated plants was elevated to the same levels as enf1.[Enf1] (Mus musculus) PubMed

 5635.

The activation of TLD1 reduced the IAA maxima at the lamina joint, shoot base, and nodes, resulting in subsequent alterations in plant architecture and tissue patterning but enhancing drought tolerance.[TLD1] (Mus musculus) PubMed

 5636.

Data show that protein kinase CIPK15 [calcineurin B-like (CBL)-interacting protein kinase] plays a key role in O(2)-deficiency tolerance: [CIPK15] (Mus musculus) PubMed

 5637.

The structure of the cytosolic portion of MgtE (residues 6-262) was determined at 2.2 A resolution by the single-wavelength anomalous dispersion method. [MgtE] (Mus musculus) PubMed

 5638.

The present study examined the expression of OsEILs in wounded rice and the DNA binding characteristics of proteins encoded by wound-inducible OsEIL1 and 2.[OsEIL1, OsEIL2] (Mus musculus) PubMed

 5639.

OsRPA1a plays an essential role in DNA repair but may not participate in, or at least is dispensable for, DNA replication and homologous recombination in rice.[OsRPA1a] (Mus musculus) PubMed

 5640.

The effects of polymorphisms of the T cell receptor beta chain on body weight and fecal oocyst shedding during coccidiosis shedding are reported.[TCR-beta] (Mus musculus) PubMed

 5641.

50 methicillin resistant Staphylococcus aureus all have the same mecA genotype. [mecA] (Mus musculus) PubMed

 5642.

PNG1 ortholog from the filamentous ascomycete Neurospora crassa is an essential protein, and its deletion results in strong polarity defects[PNG1] (Mus musculus) PubMed

 5643.

EspT-induced membrane ruffles facilitate Enteropathogenic Escherichia coli invasion into non-phagocytic cells (Mus musculus) PubMed

 5644.

results illustrate a cellular response to environmental and genetic perturbations through remodeling of the Skp1-Cullin-F-box protein complex-mediated ubiquitination system.[Cullin and Skp1] (Mus musculus) PubMed

 5645.

The first crystal structure at 1.0 and 1.7 A resolution of two recombinant Schistosoma mansoni glutathione peroxidases, carrying the active site mutations Sec43Cys and Sec43Ser, respectively.[Gpx4] (Mus musculus) PubMed

 5646.

auto-induction of murR by an activated form of MurR (Mus musculus) PubMed

 5647.

inter-spin distances suggest that the transmembrane helices of TatA subunits are arranged as a single-walled ring containing a contact interface between Ile(12) on one subunit and Val(14) on an adjacent subunit[TWIN ARGININE PROTEIN TRANSLOCASE] (Mus musculus) PubMed

 5648.

provided the first evidence for the temporal production and utilization of four different bovine foamy virus (BFV) btas mRNAs during persistent infection. [btas] (Mus musculus) PubMed

 5649.

Study solved at 2.6 A resolution the 3D structure of the TonB-dependent heme/hemoglobin outer membrane receptor ShuA from S. dysenteriae; ShuA binds to hemoglobin and transports heme across the outer membrane. [ShuA] (Mus musculus) PubMed

 5650.

Overepression of A. fumigatus AfCrzA increased the mRNA accumulation of several genes. AfRcnA affects the mRNA accumulation of genes whose expression is influenced by AfcrzA. [CrzA; RcnA] (Mus musculus) PubMed

 5651.

The authors identified a new cathepsin L termed SmCL3 using PCR strategies based on S. mansoni EST sequence data.[CL3] (Mus musculus) PubMed

 5652.

Comparative analyses of the genetic diversity between the PRRSV isolate HH08 and other Chinese as well as foreign reference strains of PRRSV were discussed based on the sequence comparison and the topology of phylogenetic trees constructed[HH08] (Mus musculus) PubMed

 5653.

Data provide evidence for neural control of tick salivary gland by myoinhibitory peptide MIP and SIFamide from the synganglion.[myoinhibitory peptide (MIP)] [SIFamide] (Mus musculus) PubMed

 5654.

UDG efficiently removes uracil from internal locations in the nucleosome where the DNA backbone is oriented away from the surface of the histone octamer, without significant disruption of histone-DNA interactions[UDG] (Mus musculus) PubMed

 5655.

Report a metabolic pattern in ciona intestinalis consistent with the presence of an As3mt ortholog in its genome and constitutive expression of the gene in prominent organs. (Mus musculus) PubMed

 5656.

The current study reveals that in the Lister427 strain of T. brucei, a gene conversion replaced the coding region for the GAF-A domain of TbrPDEB2 by the corresponding region of the upstream gene TbrPDEB1.[PDEB1 & PDEBE2] (Mus musculus) PubMed

 5657.

Study identified the zfh2 gene as a novel factor required for normal leg development in Tribolium. (Mus musculus) PubMed

 5658.

Purification of 84kDa protein/Surface expression was detected in intermediate forms between trypomastigotes and amastigotes/ the gene starts expressing when trypomastigotes begin transformation into amastigotes [SSP4/amastigote-specific surface protein] (Mus musculus) PubMed

 5659.

Urotensin-II increased resting papillary muscle length. This effect was increased in the presence of angiotensin-II, but was unaffected by the presence of endothelin-1. [Urotensin-II] (Mus musculus) PubMed

 5660.

a 42kDa protein was purified from retina and was a biotin-coupled bifunctional enzyme containing glutamine synthetase activity and glutamate decarboxylase activity. Biotin was possibly involved in activities. [p42/42kDa biotin-coupled protein] (Mus musculus) PubMed

 5661.

PhlA is a hemolysin that induces destabilization of target cell membranes in the presence of phospholipids. [PhlA] (Mus musculus) PubMed

 5662.

Identification of a bacterial GatCAB-specific element that enables this enzyme to distinguish a U1-A72 base pair from a G1-C72 pair (GatC, GatA and GatB). (Mus musculus) PubMed

 5663.

It regulates reactive oxygen species mediated by proline metabolism and protects Saccharomyces cerevisiae from oxidative stress. (review) (Mus musculus) PubMed

 5664.

The crystal structure of TbATG8B, is presented.[ATG8] (Mus musculus) PubMed

 5665.

TNFR encodes a complete receptor sequence composed of 599 amino acids, and contains four cysteine-rich domains. [TNFR] (Mus musculus) PubMed

 5666.

HIM-18, an ortholog of MUS312/Slx4, is identified as a critical player required in vivo for processing late homologous recombination intermediates in Caenorhabditis elegans.[HIM-18, SLX-1, XPF-1] (Mus musculus) PubMed

 5667.

The authors conclude that COT1 regulates elongation and branching in an independent manner, which is determined by its phosphorylation state.[COT1] (Mus musculus) PubMed

 5668.

Computational solvent mapping of both x-ray and NMR structures of the influenza M2 proton channel shows the most important binding hot spot inside the pore, surrounded by the amino acid residues Ala30, Ser31, and Gly34 [M2] (Mus musculus) PubMed

 5669.

Together, the data demonstrate that the p32, p39 and p30 proteins of FCV locate to the ER and lead to reorganization of ER membranes.[p39] (Mus musculus) PubMed

 5670.

An isogenic mutant strain defective in AtlA expression exhibited reduced survival and virulence when tested in a rat model of infective endocarditis compared with the wild-type and complemented strains.[AtlA] (Mus musculus) PubMed

 5671.

Different Pol IV isoforms play distinct roles in the maintenance of meiotically-heritable epigenetic information in the grasses.[NRPD1, NRPD2] (Mus musculus) PubMed

 5672.

Parasites with one intact GSH1 chromosomal allele lost the rescuing plasmid but not the double knockout, when grown in the absence of antibiotic, indicating the essentiality of the GSH1 gene in Leishmania.[GSH1] (Mus musculus) PubMed

 5673.

CspA mRNA is able to sense temperature downshifts, adopting functionally distinct structures at different temperatures without the aid of trans-acting factors. (Mus musculus) PubMed

 5674.

PhoB acts to diminish biofilm formation by lowering the expression of the positive regulator VpsR and modulates resistance to environmental stresses in a manner independent of RpoS. [phoB/VpsR/Vibrio cholerae El Tor C7258] (Mus musculus) PubMed

 5675.

ferredoxin is involved in secretion of CNF1 across the inner membrane in meningitis-causing E. coli K1 [CNF1} (Mus musculus) PubMed

 5676.

The expression of the AOX, well-tolerated by the cells, compensates for both the growth defect and the pronounced oxidant-sensitivity of COX-deficient human cells.[AOX] (Mus musculus) PubMed

 5677.

candida aspartate semialdehyde dehydrogenase (ASADH) is a functional dimer, with a similar overall fold and domain organization to the structurally characterized bacterial ASADHs.[aspartate beta-semialdehyde dehydrogenase] (Mus musculus) PubMed

 5678.

MOSAIC FLORAL ORGANS1 (MFO1/MADS6) regulates floral organ identity and floral meristem determinacy. [MFO1] (Mus musculus) PubMed

 5679.

MinC and MinD proteins, but not MinE, influence Bacillus subtilis cell division. Expression of these heterologous Min proteins resulted in cell elongation. [MinC/MinD/MinE/Escherichia coli strain MM294] (Mus musculus) PubMed

 5680.

DeltaIE1 had a diminished ability to infect salivary glands persistently in vivo and to reactivate from spleen explant cultures ex vivo.[IE1] (Mus musculus) PubMed

 5681.

a novel enterocin with bactericidal mode of action (Mus musculus) PubMed

 5682.

Results describe the subcellular localization and the oligomeric organization of Vipp1 from Synechocystis PCC 6803, and show that Vipp1 forms stable dimers and higher-ordered oligomers in the cytoplasm and at cytoplasmic and thylakoid membranes. (Mus musculus) PubMed

 5683.

C. elegans ATAD-3 is essential for mitochondrial activity and development [ATAD-3, also called F54B3.3] (Mus musculus) PubMed

 5684.

gamma-Glutamylcysteine synthetase from Escherichia coli has the ability to combine Glu and amines to form gamma-glutamylamides.[gamma-glutamylcysteine synthetase] (Mus musculus) PubMed

 5685.

YggT endowed E. coli cells with a tolerance for osmotic shock. [YggT] (Mus musculus) PubMed

 5686.

Ecl1 family proteins are novel regulatory factors involved in chronological lifespan among yeasts.[Ecl1] (Mus musculus) PubMed

 5687.

Direct Repeat 6 from human herpesvirus-6B encodes a nuclear protein that forms a complex with the viral DNA processivity factor p41 [gp41] (Mus musculus) PubMed

 5688.

Identification of the protease responsible for Plasmodium protein export into erythrocytes [plasmepsin V] (Mus musculus) PubMed

 5689.

A deletion in lrhA reduced the transcription levels of pchA and pchB to different degrees, and also reduced the expression of locus of enterocyte effacement -coded type 3-secreted protein, EspB.[PchA & PchB] (Mus musculus) PubMed

 5690.

Study identified 31 distinct proteins in the secretome of wild-type C. glabrata cells by MS/MS of proteins-most of these proteins are predicted to be cell wall proteins, cell wall modifying enzymes and aspartyl proteinases.[Ace2] (Mus musculus) PubMed

 5691.

function of mitochondrial Adh3 in the thermotolerant yeast Kluyveromyces marxianus [Adh3] (Mus musculus) PubMed

 5692.

The expression of CDR1 in rice and transgenic Arabidopsis thaliana in response to plant disease signals is reported.[CDR1] (Mus musculus) PubMed

 5693.

Using a chemical genetic approach the authors demonstrate that the germinal centre kinase Don3 triggers this septin reorganization during secondary septum formation.[Don3] (Mus musculus) PubMed

 5694.

plasmepsin V, an ER aspartic protease with distant homology to the mammalian processing enzyme BACE, recognizes the PEXEL motif and cleaves it at the correct site [plasmepsin V] (Mus musculus) PubMed

 5695.

The gene product catalyzed the oxidation of formate to yield hydrogen peroxide but showed no evidence of activity on the other substrates tested. [formate oxidase] (Mus musculus) PubMed

 5696.

Comparative analyses of fungal strains infected by wild-type Mycoreovirus 1 and its variants carrying rearrangements of S4 showed that S4 is non-essential for virus replication but required for efficient vertical transmission and symptom expression.[S4] (Mus musculus) PubMed

 5697.

we identified a 52 kDa human antigen/it is a modestly glycosylated mature protein with a pI 5.3/ identical to a glucoamylase previously reported from an aluminum-tolerant P. chrysogenum mutant. [glucoamylase/Penicillium chrysogenum-MEA] (Mus musculus) PubMed

 5698.

Covalently attached penicillins press against a phenylalanine residue near the active site and disturb the deacylation step.[PBP4 & PBP5] (Mus musculus) PubMed

 5699.

Together, these findings indicate that Xanthomonas campestris CLP regulates bacterial virulence gene expression in a manner negatively controlled by the c-di-GMP concentrations.[CLP] (Mus musculus) PubMed

 5700.

The authors demonstrate that SarA is capable of binding DNA with high affinity but that its binding affinity and pattern of shifted complexes in electrophoretic mobility shift assays is responsive to the redox state.[SarA] (Mus musculus) PubMed

 5701.

Ace is involved in pathogenesis of, and is useful for protection against, E. faecalis experimental endocarditis (Mus musculus) PubMed

 5702.

Lysozyme c-1 plays an important role in antibacterial defense against selected bacteria. [LYSC-1] (Mus musculus) PubMed

 5703.

the splicesosome machinery for trout cyp19b1 that includes intronic sequence and edits presumptive exon 2 to generate transcripts with 5'-UTRs of a variety of lengths [cyp19b1] (Mus musculus) PubMed

 5704.

Over-expression of wheat TaDi19A in Arabidopsis increased the plants' sensitivity to salinity stress, ABA and mannitol during the germination stage. [TaDil9A] (Mus musculus) PubMed

 5705.

Embp is a multifunctional cell surface protein that mediates attachment to host extracellular matrix, biofilm accumulation and escape from phagocytosis, and therefore is well suited for promoting implant-associated infections.[Embp] (Mus musculus) PubMed

 5706.

The authors conclude that the status of sspBC in S. aureus, as paralogues of the ancestral scpAB genes, facilitated a different activation mechanism, a stable proSspB isoform and modified Staphostatin function.[SspB & SspC] (Mus musculus) PubMed

 5707.

The bE1/bW1 complex is required and sufficient to initiate pathogenic development and sexual reproduction.[bE1 and bW1] (Mus musculus) PubMed

 5708.

Synthetic lethal interactions between members of the cohesin complex and CTF4, RAD27, and components of the alternative RFC(CTF18) complex.[CTF18] (Mus musculus) PubMed

 5709.

study concludes ORFV125's mechanism of action is Bcl-2-like and propose that the viral protein's combined ability to bind to a range of BH3-only proteins as well as the active form of Bax provides significant protection against apoptosis [ORFV125] (Mus musculus) PubMed

 5710.

RecF, recO and recR proteins are essential for DNA double-strand-break repair. [recO] (Mus musculus) PubMed

 5711.

data suggest that Zn(2+)-Atx1 can form in vivo [Atx1] (Mus musculus) PubMed

 5712.

Data show that p24 delta2 and alpha3 furnish subcompartments of the secretory pathway with specific sets of machinery cargo to provide the proper microenvironments for efficient and correct secretory protein transport and processing [p24alpha3, delta2]. (Mus musculus) PubMed

 5713.

Visualization of surface potentials around the substrate-binding region of the enzymes have demonstrated a more positive potential for Aliivibrio salmonicida uracil-DNA N-glycosylase(asUNG) compared with Vibrio cholerae UNG.[uracil-DNA N-glycosylase] (Mus musculus) PubMed

 5714.

native crystals of RspB diffracted to a resolution of 2.5 A using an in-house X-ray source, while the selenomethionine-derivative crystals diffracted to a resolution of 2.2 A using synchrotron radiation. [RspB] (Mus musculus) PubMed

 5715.

DEP and AFO are both required to ensure sexual reproduction in rice. [DEP,AFO] (Mus musculus) PubMed

 5716.

findings show that the transcriptional regulator VpsT directly senses cyclic di-guanosine monophosphate to inversely control extracellular matrix production and motility, which identifies VpsT as a master regulator for biofilm formation [VpsT] (Mus musculus) PubMed

 5717.

Although ORF50 protein does not directly bind to the ORF61 and ORF60 promoters in vitro, the authors show the association of ORF50 protein with these two promoters in vivo.[ORF61, ORF60, ORF50] (Mus musculus) PubMed

 5718.

Both the dimeric and folded monomeric forms of HIV-2 protease were characterized by solution NMR and compared with HIV-1 protease.[HIV-2 protease] (Mus musculus) PubMed

 5719.

OsIRL may behave as an antioxidant in response to oxidative stresses in suspension-cultured cells as well as during root development in rice. [OsIRL] (Mus musculus) PubMed

 5720.

CovS mutation uniformly repressed capsule expression and hampered keratinocyte adherence in all serotypes. [CovS] (Mus musculus) PubMed

 5721.

Functional studies and modeling of pore-lining residue mutants of the influenza a virus M2 ion channel (Mus musculus) PubMed

 5722.

BAFF and its receptors during B-cell activation and autoantibody production in rabbits derived from selective breeding to develop a reproducible rabbit model of Systemic Lupus Erythematosus, were investigated.[BR3, TACI] (Mus musculus) PubMed

 5723.

While NPR1 has a positive effect on pathogen resistance, it has a negative effect on symbiotic interactions, by inhibiting root hair deformation and nodulin expression.[NPR1] (Mus musculus) PubMed

 5724.

SigA binds to epithelial HEp-2 cells as well as being able to induce fodrin degradation in vitro and in situ, further extending its documented role in the pathogenesis of Shigella infections.[SigA] (Mus musculus) PubMed

 5725.

Structural and functional studies of Aspergillus clavatus N(5)-carboxyaminoimidazole ribonucleotide synthetase (Mus musculus) PubMed

 5726.

these data thus suggest that the PRMT1 plays a key role as a cellular regulator of HSV-1 replication through ICP27 RGG-box methylation.(ICP27) (Mus musculus) PubMed

 5727.

identified a JmjC domain protein in Neurospora, DNA METHYLATION MODULATOR-1 (DMM-1), that prevents aberrant spreading of DNA and histone H3K9 methylation from inactivated transposons into nearby genes [DMM-1] (Mus musculus) PubMed

 5728.

L alpha-glucan phosphorylase has higher catalytic efficiency toward both linear and branched alpha-glucans in the synthesis direction than in the degradation direction.[L alpha-glucan phosphorylase] (Mus musculus) PubMed

 5729.

findings show that translocation and phosphorylation of CagA are necessary, but not sufficient, for the induction of hummingbird phenotype in AGS cells infected with Helicobacter pylori [CagA] (Mus musculus) PubMed

 5730.

The cloning and characterization of Francisella tularensis MEP synthase, a MEP pathway enzyme and potential target for antibiotic development, is described.[MEP synthase] (Mus musculus) PubMed

 5731.

In addition to its localization in the cytoplasm and in the nucleoid, a significant amount of Hfq protein is located at the cell periphery.[Hfq] (Mus musculus) PubMed

 5732.

Mapping of the signal peptide-binding domain of Escherichia coli SecA using Forster resonance energy transfer. (Mus musculus) PubMed

 5733.

identified DNF1 gene encoding a subunit of a signal peptidase complex highly expressed in nodules; propose symbiosome development requires secretion of proteins through coordinated upregulation of a nodule-specific pathway exemplified by DNF1[DNF1] (Mus musculus) PubMed

 5734.

We conclude that Erm dependence functionally distinguishes intermediate neural progenitors from neuroblasts in the Drosophila larval brain, balancing neurogenesis with stem cell maintenance.(EARMUFF PROTEIN, DROSOPHILA) (Mus musculus) PubMed

 5735.

Deletion of one mgt1 allele from L. major led to increased virulence, while deletion of one allele of mgt2 resulted in slower growth and total loss of virulence in vitro and in vivo.[MGT1, MGT2] (Mus musculus) PubMed

 5736.

The authors show that bromodomain factor 2 (BDF2), is expressed in discrete regions inside the nucleus of all the parasite life cycle stages and binds H4 and H2A purified histones from Trypanosoma cruzi.[BDF2] (Mus musculus) PubMed

 5737.

DR0093 was confirmed to encode gamma-carotene ketolase to catalyse the ketolation of g-carotene derivatives in the native host. [DR0093/Deinococcus radiodurans strain R1] (Mus musculus) PubMed

 5738.

the collagen-binding protein SdrI of S. saprophyticus, a member of the Sdr-family, can also bind fibronectin.[SdrI/Staphylococcus saprophyticus strain 7108] (Mus musculus) PubMed

 5739.

The authors observed that substitution of both chromosomal TXN1 alleles was only possible upon parasite complementation with an episomal copy of the gene indicating the essentiality of TXN1.[TXN1] (Mus musculus) PubMed

 5740.

Results describe the subcellular localization of ICP27 and its colocalization with cellular RNA export factors Aly/REF and TAP/NXF1. (Mus musculus) PubMed

 5741.

Proposed is that the peptide region 207-216 is a flexible loop and that H208, Y211, R212 and Q214 of this loop are involved in the correct assembly of the DNA-integrase complex during integration.[Integrase] (Mus musculus) PubMed

 5742.

Vrn-D4, which was mapped within a 1.8 cM interval flanked by markers Xcfd78 and Xbarc205 in the centromeric region of chromosome 5D.[Vrn-D4] (Mus musculus) PubMed

 5743.

the Ile(13) residue of microcin J25's tetrapeptide sequence (VGIG) is only required for interaction with FhuA, and VGIG is not a major recognition element by SbmA. [FhuA/SbmA/Escherichia coli AB1133] (Mus musculus) PubMed

 5744.

Hypophosphorylation of VSV P protein was found to occur in neuronal cell lysates, but not within budded virions from the same IFN-beta-treated cells. phosphoprotein P. (Mus musculus) PubMed

 5745.

These data suggest that Soa proteins are components of a molecular mechanism controlling lipase gene expression in response to extracellular triacylglycerol.[SOA1, SOA2] (Mus musculus) PubMed

 5746.

The fission yeast Schizosaccharomyces pombe Ssp1 kinase, which controls G2/M transition and response to stress, is the putative CaMKK. (Mus musculus) PubMed

 5747.

irvA promotes Dextran-dependent aggregation not only by GbpC, a cell surface glucan-binding protein, but also via an increase in the major surface adhesin P1 [irvA] (Mus musculus) PubMed

 5748.

NS3h translocates on ssDNA as a monomer, but the translocase activity does not correspond to comparable DNA unwinding activity or protein displacement activity under identical conditions.[NS3] (Mus musculus) PubMed

 5749.

A tau class GST gene (OsGSTU17) was cloned from rice, which encodes a protein of 223 amino acid residues with a calculated molecular mass of 25.18 kDa. The recombinant OsGSTU17 formed a homodimer protein and showed GSH-conjugating activity...[OsGSTU17] (Mus musculus) PubMed

 5750.

The assembly of F(1)F(O)-ATP synthase is disrupted upon interference of RNA editing in Trypanosoma brucei. [F(1)F(O)-ATP synthase] (Mus musculus) PubMed

 5751.

Prohibitin 1 (PHB1) and 2 (PHB2) appear to be indispensable for mitchondrial translation.[PHB1, PHB2] (Mus musculus) PubMed

 5752.

Identified MtMTP1, a Zn transporter of the CDF family in the legume model plant Medicago truncatula. [MtMTP1] (Mus musculus) PubMed

 5753.

In yeast, the secretion of SDF-2-like activity is GRASP dependent, triggered by nitrogen starvation, and requires autophagy proteins as well as medium-chain fatty acyl CoA generated by peroxisomes.[Acb1] (Mus musculus) PubMed

 5754.

These findings suggest that FAM3C is involved in retinal laminar formation processes in vertebrates.(XFAM3C) (Mus musculus) PubMed

 5755.

The temperature sensitivity of the photoreaction of YcgF suggests that this protein could have a biological function as a temperature sensor as well as behaving as a light sensor [YcgF] (Mus musculus) PubMed

 5756.

the solution structure of the norsolorinic acid synthase (NSAS) holo ACP domain of type I polyketide synthase [type I polyketide synthase] (Mus musculus) PubMed

 5757.

crystals of the reduced enzyme and of the enzyme in complex with a wide range of ligands typically led to high-quality complete data sets to 1.30-1.60 A resolution[SYE4] (Mus musculus) PubMed

 5758.

Crystals were obtained in space group P4(1)2(1)2 and diffracted to 2.0 A resolution, with unit-cell parameters a = b = 89.4, c = 179.6 A.[diaminopimelate epimerase] (Mus musculus) PubMed

 5759.

data indicate that LpxC can use either Fe(2+) or Zn(2+) to activate catalysis in vitro and possibly in vivo, which may allow LpxC to function in E. coli grown under different environmental conditions [LpxC] (Mus musculus) PubMed

 5760.

Genetic analysis revealed hybrid breakdown involving weakness phenotype in the F2 progenies to be controlled by two recessive genes: hybrid breakdown 2 (hbd2) and hbd3.[hbd2 and hbd3] (Mus musculus) PubMed

 5761.

the crystals were thought to belong to space group P4(2)2(1)2, with unit-cell parameters a = 105.5, b = 105.5, c = 62.4 A. However, the R factors remained high following initial processing of the data[dihydrodipicolinate synthase (S pneumoniae OXC141)] (Mus musculus) PubMed

 5762.

Data imply that a SUMO system essential for regulating cell cycle progression might exist in the procyclic-form T. brucei [SUMO]. (Mus musculus) PubMed

 5763.

Expb1 are needed for pollen separation and stigma penetration. [Expb1] (Mus musculus) PubMed

 5764.

Membrane targeting by RSBP-1 is essential for EAT-16 activity.[RSBP-1, EGL-10] (Mus musculus) PubMed

 5765.

The authors conclude that H. pylori HspA is involved in intracellular nickel sequestration and detoxification and plays a novel role as a specialized nickel chaperone involved in nickel-dependent maturation of hydrogenase.[HspA] (Mus musculus) PubMed

 5766.

Together, these data support the hypotheses that BinA functions as a phosphodiesterase and that c-di-GMP activates cellulose biosynthesis.[BinA] (Mus musculus) PubMed

 5767.

DSM1 may act as an early signal regulating the responses to drought stress in rice. Drought hypersensitivity of dsm1 is partially due to a decrease in reactive oxygen species scavenging. [DSM1] (Mus musculus) PubMed

 5768.

Hd6 requires functional Hd1 for flowering repression under long day conditions, and does not affect circadian rhythms. (Mus musculus) PubMed

 5769.

study evaluated the role of Cwt1p in morphogenesis, cell wall architecture & virulence; findings suggest that an intermediate dosage of Cwt1 affects phenotypes profoundly, while its complete absence may elicit compensatory responses of C. albicans [Cwt1] (Mus musculus) PubMed

 5770.

Antisense MtSucS1 sucrose synthase provoked an impaired arbuscular mycorrhiza fungal colonization, and plants had reduced growth and reproduction, photosynthetic activity, and an impaired nutritional status. [SucS1] (Mus musculus) PubMed

 5771.

Phosphoenolpyruvate carboxylase binds phosphatidic acid and its activity is inhibited by anionic phospholipids. [PepC] (Mus musculus) PubMed

 5772.

Stp1 is a functionally conserved orthologue of the mammalian Site-2 protease and Stp1 cleaves Sre1 within its predicted first transmembrane segment (Stp1). (Mus musculus) PubMed

 5773.

These data demonstrate a role of the E3 ubiquitin ligases in CTA1 retro-translocation.[CTA1] (Mus musculus) PubMed

 5774.

ModE of C. jejuni differentially regulates both molybdenum and tungsten transport (ModE). (Mus musculus) PubMed

 5775.

Dissection of the opposing synthetic and hydrolytic functions of trypanothione synthetase-amidase (TRYS) in order to independently study their respective roles in T. brucei cell virulence and viability (TRYS). (Mus musculus) PubMed

 5776.

characterization of PTK2 role in turgor regulation; osmoadaptation role is unrelated to activity of MAP kinase cascade; it acts in an alternative pathway that, like the MAP kinase cascade, also involves ion transport mediated osmoadaptation [Ptk2] (Mus musculus) PubMed

 5777.

Identified is a new icd gene encoding isocitrate dehydrogenase from Helicobacter pylori.[isocitrate dehydrogenase] (Mus musculus) PubMed

 5778.

Compared are the enzyme kinetics of alpha-glucosidase from Saccharomyces cerevisiae during denaturation by guanidinium chloride and SDS.[alpha-glucosidase] (Mus musculus) PubMed

 5779.

Comparison of eIF4G(tsv1) gene sequences among susceptible and resistant plants suggested the association of RTSV resistance with one of the single nucleotide polymorphism sites found in exon 9 of the gene [eIF4G, translation initiation factor] (Mus musculus) PubMed

 5780.

Erl1 and Gin-N are orthologs and might be involved in the control of hyphal growth in planta [erl1] (Mus musculus) PubMed

 5781.

crystal structure of Dpr [Dpr] (Mus musculus) PubMed

 5782.

These data suggest that TolC function is required for Francisella tularensis to inhibit host cell death and dampen host immune responses. (Mus musculus) PubMed

 5783.

AatA was shown to enhance adhesion of avian pathogenic Escherichia coli to chicken embryo fibroblast cells and to contribute to APEC virulence.[AatA] (Mus musculus) PubMed

 5784.

crystal structure of an E. coli AdiC variant bound to Arg at 3.0 A resolution [AdiC] (Mus musculus) PubMed

 5785.

gene was found to exist in most pathogenic strains but scarcely in non-invasive isolates[Streptococcus suis, strain 05ZYS ; IgA1 protease] (Mus musculus) PubMed

 5786.

In this study, 16 20-mer-long synthetic peptides spanning the entire ribosomal phosphoprotein sequence were evaluated by means of receptor-ligand assays with human red blood cells. (Mus musculus) PubMed

 5787.

evidence that PfUCHL3 is essential to parasite survival [UCHL3] (Mus musculus) PubMed

 5788.

study concluded that atfA is involved in conidial germination via carbon and nitrogen source metabolism [atfA] (Mus musculus) PubMed

 5789.

WRN-1 functions together with RPA-1 upstream of ATM and ATR to trigger cell cycle arrest in response to double-strand DNA breaks. [ATR] (Mus musculus) PubMed

 5790.

Rrp36p protein is nucleolar and interacts with 90S and pre-40S preribosomal particles. Its depletion affects early cleavages of the 35S pre-rRNA and results in a rapid decrease in mature 18S rRNA levels. (Rrp36p) (Mus musculus) PubMed

 5791.

Fbl and ClfA bind the same site in fibrinogen by similar mechanisms [Fbl] (Mus musculus) PubMed

 5792.

A H145Y mutation in metK is responsible for a 70% decrease in intracellular S-adenosylmethionine content which probably affects the activities of numerous SAM-dependent enzymes.[metK] (Mus musculus) PubMed

 5793.

This effect of AgC10 is likely due to its ability to induce L-selectin shedding from the monocyte membrane, since pharmacologic blocking of this shedding prevents AgC10 activity. (Mus musculus) PubMed

 5794.

These results indicate that OsACDR1 plays an important role in the positive regulation of disease resistance in rice.[OsACDR1] (Mus musculus) PubMed

 5795.

We cloned the EP2 gene by way of a map-based cloning strategy. (Mus musculus) PubMed

 5796.

ORF19 knock down by RNA interference inhibited virus replication indicating that the gene is indispensable for HvAV-3e replication.[ORF19] (Mus musculus) PubMed

 5797.

uhpA involved in regulating sulfur assimilation pathways upon up-shift high osmotic treatment for 30 min [UhpA] (Mus musculus) PubMed

 5798.

a dense granule protein that displays no homology with other proteins/ behaves similarly to both GRA2 and GRA6/ may bind non-specifically to the moving junction complex in vitro. [GRA12] (Mus musculus) PubMed

 5799.

Structural perturbation results from a buried thiolate anion attributed to suppression of the Cys sulfhydryl group pK(a) from 9.4 in aqueous solvent to 7.5 in the hydrocarbon ruler microenvironment. [PagP] (Mus musculus) PubMed

 5800.

The results suggest that the physiological role of beta-N-acetylglucosaminidase is to degrade the chitooligosaccharides transported through membrane following hydrolysis of chitin into beta-N-acetylglucosamine (beta-N-acetylglucosaminidase). (Mus musculus) PubMed

 5801.

a direct interaction between m152 and RAE-1 (Mus musculus) PubMed

 5802.

These results raise the possibility that loss of OsUBP6 is functionally compensated for by an as-yet unknown OsUBP homolog during later stages of development in rice plants.[OsUBP6] (Mus musculus) PubMed

 5803.

Metformin attenuated the progression of aortic atherosclerosis via down-regulation of nuclear NF-kappaB subunit p65 (RelA). (Mus musculus) PubMed

 5804.

Results show that REL2 is crucial for A. aegypti immunity upon infection with Escherichia coli and Bacillus subtilis.[REL2] (Mus musculus) PubMed

 5805.

The results suggest that the physiological role of beta-N-acetylglucosaminidase (cbsA)is to degrade the chitooligosaccharides transported through membrane following hydrolysis of chitin into beta-N-acetylglucosamine (cbsA). (Mus musculus) PubMed

 5806.

The effect of suppressing the lepB protein on twin-arginine signal peptide metabolism is reported.[lepB] (Mus musculus) PubMed

 5807.

The half-life of p130, relative to control cells, was decreased in the cytoplasm in the presence of human papillomavirus 6 E7 or human papillomavirus 16 E7, but only decreased by HPV 6 E7 in the nucleus. (Mus musculus) PubMed

 5808.

A recent study now shows that two additional tyrosines within Tir recruit the inositol phosphatase SHIP2 to generate a PI(3,4)P2-enriched membrane platform that stabilizes pedestal assembly.[Tir] (Mus musculus) PubMed

 5809.

Together, this study suggests that BFV activates the NF-kappaB pathway through BTas to enhance viral transcription.[BTas] (Mus musculus) PubMed

 5810.

the activation mechanism of botulinum neurotoxin type E upon nicking and subsequent reduction of disulfide bond (Mus musculus) PubMed

 5811.

Orysa;CycB1;1 expression is critical for endosperm formation via the regulation of mitotic division, and the endosperm plays an important role in maintenance of embryo development in rice.[Orysa;CycB1;1] (Mus musculus) PubMed

 5812.

LAP was optimally active at slightly alkaline pH and its activity was dependent on divalent metal ions. [Lap] (Mus musculus) PubMed

 5813.

TgLAP is a functional aminopeptidase in the cytoplasm. (Mus musculus) PubMed

 5814.

PfRh5 binds to glycosylated receptors on erythrocyte surface/localises to rhoptries in merozoites and follows the tight junction during the process of erythrocyte invasion/may play a key role in invasion. [Reticulocyte-binding protein homologue 5/PfRh5] (Mus musculus) PubMed

 5815.

Neither BoNT/A3 nor BoNT/A4 possessed autocatalytic activity. [BoNT/A3, BoNT/A4] (Mus musculus) PubMed

 5816.

Deletion of amino acids 3-11 of NikR abolished the nickel-responsive activity and enhanced nonspecific DNA binding. [NikR] (Mus musculus) PubMed

 5817.

AP180 interacts with the cytoplasmic domain of Vamp7B & directs it into clathrin-coated vesicles on contractile vacuoles, regulating the internal distribution of fusion-competent SNARE proteins & limiting homotypic fusions among contractile vacuoles. (Mus musculus) PubMed

 5818.

CP250, a 2110-AA corona component, is an acidic coiled-coil protein present throughout interphase, disappearing during prophase & reappearing at late telophase. AAs 756-1148 are enough for centrosomal targeting & cell-cycle-dependent association. (Mus musculus) PubMed

 5819.

Results of this study support the active role of rpoS in the low salinity adaptation of Vibrio vulnificus by regulating the expression of virulence and low salinity-associated factors[RpoS] (Mus musculus) PubMed

 5820.

The study reports that substitution of the acidic surface residue Glu226 to Ala in ascorbate peroxidase from Leishmania major alters the 5 coordinate high spin (5cHS) to a 6 coordinate low spin (6cLS) form at pH 7.5.[ascorbate peroxidase] (Mus musculus) PubMed

 5821.

These findings support acceleration of gp41-induced membrane fusion by early pre-hairpin intermediate conformation and fusion arrest after folding to the final six-helix bundle structure.[gp41] (Mus musculus) PubMed

 5822.

The Erect Panicle 3 (EP3) gene has been mapped and cloned. (Mus musculus) PubMed

 5823.

evidence is provided for the function of the periplasmic fumarate reductase FccA and the decaheme c-type cytochrome MtrA in periplasmic electron transfer reactions in the gammaproteobacterium Shewanella oneidensis.[FccA] (Mus musculus) PubMed

 5824.

The X-ray crystal structure of CmlS determined at 2.2 A resolution, is determined.[CmlS] (Mus musculus) PubMed

 5825.

The heterotrimeric G-protein alpha subunit protein RGA1 participates in the regulation of cell number in a developmental stage-dependent manner. [RGA1] (Mus musculus) PubMed

 5826.

The authors demonstrated that Aur and SspA, two proteases that are overexpressed in the sigB mutant strain and are capable of degrading Bap, inhibit biofilm formation.[Bap & SspA & Aur] (Mus musculus) PubMed

 5827.

FRH is a core component of the central oscillator that is permissive for rhythmicity but appears not to modulate periodicity. (Mus musculus) PubMed

 5828.

uncovers the strategy used by the photosynthetic alpha-proteobacterium Rhodobacter sphaeroides to procure the cobamide it needs to grow on acetate as a carbon and energy source requires CbiZ enzyme. [CbiZ] (Mus musculus) PubMed

 5829.

14-3-3 post-translational modifications act in combination to affect encystation in Giardia duodenalis. [14-3-3] (Mus musculus) PubMed

 5830.

Genetic analysis confirmed that rdxA and rdxB are cotranscribed and induced during in vivo growth in the chick intestinal tract, but an absence of these genes did not strongly impair C. jejuni for commensal colonization.[RdxB] (Mus musculus) PubMed

 5831.

the effect of the single-residue mutation of leucine 42 to arginine (L42R) centrally positioned in the polypeptide binding pocket of SecB on its chaperonin function [SecB] (Mus musculus) PubMed

 5832.

The authors created an hdrR overexpression strain and showed that it could reproduce each of the hdrM competence and mutacin phenotypes, indicating that HdrM acts as a negative regulator of HdrR activity.[hdrR & hdrM] (Mus musculus) PubMed

 5833.

Data suggest that the ICP27-independent gC expression occurred even in the absence of viral DNA synthesis, indicating that the silencing element helps to regulate the tight DNA replication-dependent expression of gC [ISP27]. (Mus musculus) PubMed

 5834.

The data confirm that covS plays a direct role in regulating Group A Streptococcus virulence[covS] (Mus musculus) PubMed

 5835.

Although ORFV024 interferes with activation of the NF-kappaB signaling pathway, its deletion from the OV-IA82 genome had no significant effect on disease severity, progression, and time to resolution in sheep.[ORFV024] (Mus musculus) PubMed

 5836.

PAKB pathway is central to eliciting the appropriate morphogenetic response by the pathogen to the host environment independently of the common temperature signal, thus separating the temperature- and intracellular-dependent signaling systems[PAKB] (Mus musculus) PubMed

 5837.

X-ray diffraction data to 1.85 A resolution were collected from a monoclinic crystal of 1-deoxy-D-xylulose 5-phosphate reductoisomerase. [1-deoxy-D-xylulose 5-phosphate reductoisomerase] (Mus musculus) PubMed

 5838.

X-ray diffraction data of phosphoglucose isomerase to 1.5 A resolution were collected from an orthorhombic crystal form belonging to space group P2(1)2(1)2(1) with unit-cell parameters a = 103.3, b = 104.1, c = 114.6 A.[phosphoglucose isomerase] (Mus musculus) PubMed

 5839.

Here, the authors show that self-protection is provided by the pneumococcal LiaFSR system, which senses the damage inflicted to the cell wall by CbpD, LytA, and LytC.[LiaF, LiaS & LiaR] (Mus musculus) PubMed

 5840.

A Trypanosoma brucei DNA primase gene, PRI1, that encodes a 70-kDa protein that localizes to the kinetoplast and is essential for both cell growth and kinetoplast DNA replication, is described.[PRI1] (Mus musculus) PubMed

 5841.

X-ray diffraction data of alternative oxidase were collected at 100 K and were processed to 2.9 A resolution with 93.1% completeness and an overall R(merge) of 9.5%.[cyanide-insensitive alternative oxidase] (Mus musculus) PubMed

 5842.

This is the first study to demonstrate the roles of antisera against sortase A (SrtA) and lipase 2 in the inhibition of biofilm formation in S. aureus.[SrtA; lipase2] (Mus musculus) PubMed

 5843.

Xenopus Wnt11b is identified as a potential pronephric inducer. [Wnt11b] (Mus musculus) PubMed

 5844.

DadA with 44 kDa molecular mass possessed FAD as cofactor, and showed the highest activity to D-proline. [DadA] (Mus musculus) PubMed

 5845.

fetal cortisol concentrations are suppressed by adenosine A(1) receptor activity, largely though a direct adrenal mechanism[ADENOSINE A1 RECEPTOR] (Mus musculus) PubMed

 5846.

The IE62 consensus binding site functions to down-modulate IE62 activation, and interaction of IE62 with this sequence may result in loss or decrease of the ability of IE62 to recruit cellular factors needed for full promoter activation.[IE62] (Mus musculus) PubMed

 5847.

These data indicate that the pre-S2 domain of the L protein serves an important role for virus assembly, but does not participate as part of the M protein or as a subdomain of the L protein in virus entry.[L] (Mus musculus) PubMed

 5848.

Mutations E627K, D701N, and E677G had no major impact on virus replication in the respiratory tracts of mice and ferrets or on pathogenesis.[PB2] (Mus musculus) PubMed

 5849.

Efficient budding of the tacaribe virus matrix protein z requires the nucleoprotein.(Z PROTEIN) (Mus musculus) PubMed

 5850.

The ORF3 protein of hepatitis E virus was found to interact with CIN85 and compete with the formation of the growth factor receptor-Cbl-CIN85 complex, resulting in the reduced ubiquitination of CIN85.[ORF3] (Mus musculus) PubMed

 5851.

The structure reveals variability in the order and position of a small domain, which forms a lid for the active site and serves to capture conformations likely to exist during the catalytic cycle.[glutathione synthetase] (Mus musculus) PubMed

 5852.

The minicircle-encoded antisense transcripts, which are stabilized by RET1-catalyzed uridylylation, may direct a nucleolytic cleavage of multicistronic precursors.[RET1] (Mus musculus) PubMed

 5853.

palH plays a very important role in controlling the alkaline protease level in A. oryzae. [palH] (Mus musculus) PubMed

 5854.

Genetic ablation of the APT transporter results in rapid death of parasites.[APT] (Mus musculus) PubMed

 5855.

Data presented here demonstrate that Stomatin like protein-2 is a novel tegument protein located in the host-parasite interface.[Stomatin like protein-2] (Mus musculus) PubMed

 5856.

we show a mitochondrial localization for 3-hydroxy-3-methyl-glutaryl Coenzyme A (HMG-CoA) synthase while mevalonate kinase is associated mainly with the glycosomal matrix. [3-hydroxy-3-methyl-glutaryl Coenzyme A synthase/ mevalonate kinase] (Mus musculus) PubMed

 5857.

we show a mitochondrial localization for 3-hydroxy-3-methyl-glutaryl Coenzyme A (HMG-CoA) synthase while mevalonate kinase is associated mainly with the glycosomal matrix. [3-hydroxy-3-methyl-glutaryl Coenzyme A synthase/ mevalonate kinase] (Mus musculus) PubMed

 5858.

we describe the cloning and characterisation of an S. mansoni bone morphogenetic protein(SmBMP). SmBMP is expressed throughout the mammalian life-cycle of the parasite in both male and female schistosomes. [bone morphogenetic protein/BMP] (Mus musculus) PubMed

 5859.

However, both mutants with an altered N-terminal cysteine were inactive. (Mus musculus) PubMed

 5860.

Based on these experimental data, the authors conclude that Trichomonas vaginalis malate dehydrogenase is negatively regulated by miR-1.[malate dehydrogenase] (Mus musculus) PubMed

 5861.

Both XBcl9 and XPygo2 are required to induce supernumerary axis and dorsal gene activation in Xenopus embryos. [Pygo2] (Mus musculus) PubMed

 5862.

This study analyzed the behavior of two highly homologous rice HKT transporters in plant cells, HKT2;1 and HKT2;2, that show differential potassium permeabilities in heterologous systems.[HKT2;1, HKT2;2] (Mus musculus) PubMed

 5863.

This study demonstrates that the regulation of a mechanism of multidrug resistance genes and expression of virulence genes show considerable overlap; the role of ramA in both is demonstrated.[RamA] (Mus musculus) PubMed

 5864.

These results suggest that PhaR regulates the expression of phaP in Rhodobacter sphaeroides FJ1.[PhaR] (Mus musculus) PubMed

 5865.

the CRN7 role in chemotaxis and phagocytosis is through its effect on the actin cytoskeleton [CRN7] (Mus musculus) PubMed

 5866.

by expression analysis of deoxynivalenol (DON)-induced samples using GeneChip Wheat Genome Array, a DON-resistance related gene TaUGT3 was cloned and characterized from a scab resistant wheat variety [UGT3] (Mus musculus) PubMed

 5867.

Here, the authors show that deletion of 3 or 9 residues at the C terminus of IpaB leads to fast constitutive secretion of late effectors, as observed in a DeltaipaB strain.[IpaB] (Mus musculus) PubMed

 5868.

Mp1p ligand binding domain 2 has a function as a fatty acid-binding protein [Mp1p] (Mus musculus) PubMed

 5869.

The CEK1-mediated MAPK pathway is involved in beta-glucan exposure in a fungal pathogen, hence influencing dectin-1-dependent immune cell recognition.[CEK1] (Mus musculus) PubMed

 5870.

ZmRdRP1 was involved in antiviral defense in maize. (Mus musculus) PubMed

 5871.

All new variant Chlamydia trachomatis isolates from 2006 displayed an identical ompA genotype E and multilocus sequence typing MLST profile, which strongly indicates a clonal spread of the nvCT. (Mus musculus) PubMed

 5872.

findings suggest ZmsHSP might have a function in cytokinin response in Zea mays[sHSP, Zea mays] (Mus musculus) PubMed

 5873.

FgEnd1 is a putative member of the endocytic machinery, although it acts through a different mechanism from ScEnd3 or ScEnd4 of S. cerevisiae. End1. (Mus musculus) PubMed

 5874.

CcCel6C consists of a distorted seven-stranded beta/alpha barrel and has an enclosed tunnel [CcCel6C] (Mus musculus) PubMed

 5875.

findings show that a peroxidase (IMPer), secreted by the Anopheles gambiae midgut, and dual oxidase form a dityrosine network that decreases gut permeability to immune elicitors [IMPer] (Mus musculus) PubMed

 5876.

Data suggest that LmaMPK7 protein kinase activity may be implicated in parasite growth control and thus relevant for the development of nonproliferating stages during the infectious cycle [MPK7]. (Mus musculus) PubMed

 5877.

Data describe the identification and function of the dynamin-like protein DLP1 from the protist parasite Entamoeba histolytica [DLP1]. (Mus musculus) PubMed

 5878.

study demonstrates the activity of IrvR is controlled in a manner analogous to that of the CI protein; it has ability to undergo autocleavage, which promotes proteolytic degradation of its DNA binding domain leading to derepression of irvA [IrvR] (Mus musculus) PubMed

 5879.

HsfA4a of wheat and rice confers cadmium tolerance by upregulating metallothionein gene expression in planta. [TaHsfA4a] (Mus musculus) PubMed

 5880.

HsfA4a of wheat and rice confers cadmium tolerance by upregulating metallothionein gene expression in planta. [OsHsfA4a] (Mus musculus) PubMed

 5881.

The recombinant CYP704B2 protein catalyzed the hydroxylation of palmitic acid and unsaturated C18 fatty acids in the omega position of the carbon chain. CYP704B2 is required for synthesis of cutin monomers.[CYP704B2] (Mus musculus) PubMed

 5882.

Reveal myozap as a previously unrecognized component of a Rho-dependent signaling pathway that links the intercalated disc to cardiac gene regulation and implicate it in the pathogenesis of cardiomyopathy. (Mus musculus) PubMed

 5883.

(KcsA potassium channel) The technique of electron spin-echo envelope modulation by deuterium demonstrates that KcsA inserts into the membrane without creating water-accessible crevices along its protein surface. (Mus musculus) PubMed

 5884.

Results indicate that FlgT functions to stabilize the flagellar apparatus at the pole of the cell. [FlgT] (Mus musculus) PubMed

 5885.

The relationship of agr expression with biofilm formation in methicillin-resistant S. aureus strains isolated in Greek patients is reported.[agr] (Mus musculus) PubMed

 5886.

A single nucleotide substitution in hyaluronate lyase, resulting in an amino acid change at position 199, was present in a highly-conserved region of the protein in isolates not producing active enzyme.[hylA] (Mus musculus) PubMed

 5887.

Studies shoe that IFT144 and IFT139, two complex A proteins, are encoded by FLA15 and FLA17, respectively, and Temperature-sensitive mutations in FLA15 and FLA17 show defects in retrograde intraflagellar transport (IFT): [FLA15 and FLA17] (Mus musculus) PubMed

 5888.

Results suggest that AspA and AspC interact with each other and are important for normal development, especially for preventing the inappropriate emergence of germ tubes and branches [AspA; AspC]. (Mus musculus) PubMed

 5889.

full length gene, named TaGly I, was cloned, sequenced and characterized; TaGly I might play a role in response to diverse stresses in plants[Glyoxalase I] (Mus musculus) PubMed

 5890.

study shows that PdkA & PdkB function as the key activation loop kinases; cells lacking PdkA & PdkB are defective in PKB activation, chemotaxis & fruiting body formation upon nutrient deprivation[PKBR1] (Mus musculus) PubMed

 5891.

OsBIANK1 may be involved in regulation of disease resistance response in rice.[BIANK1 protein] (Mus musculus) PubMed

 5892.

ILI1-Os IBH1 is a conserved pair of antagonistic HLH/bHLH transcription factors that function downstream of BZR1 to mediate brassinosteroid regulation of cell elongation. [ILI1; IBH1] (Mus musculus) PubMed

 5893.

Taken together, the results presented here demonstrate a novel, submitochondrial localization of the cytosolic phospholipase A2like protein in Aspergillus oryzae.[cytosolic phospholipase A2-like protein] (Mus musculus) PubMed

 5894.

The biochemical properties of site-directed mutants indicate that H45, C51, and C53 of GroES make up an oxidation-sensitive zinc-binding site that may donate the bound metal to a zinc acceptor.[GroES] (Mus musculus) PubMed

 5895.

An important region in the hepatitis C virus (HCV) NS4B protein is identified which might be implicated in the HCV life cycle and possibly in the formation of the membranous web.[NS4B] (Mus musculus) PubMed

 5896.

eight characteristic mutations in the HCV-1b core gene related to the occurrence of hepatocellular carcinoma were identified [1b core protein] (Mus musculus) PubMed

 5897.

Temperature-accelerated molecular dynamics is applied to the GroEL subunit, a 55-kDa, three-domain protein, and HIV-1 gp120.[gp120] (Mus musculus) PubMed

 5898.

The recombinant extracellular var2CSA region is correctly folded and it binds with high affinity and specificity to chondroitin sulfate A.[var2CSA] (Mus musculus) PubMed

 5899.

Lana-1-induced serum response element activation was inhibited by the dominant-negative N-terminal domain of the human MED25 mediator subunit, suggesting that this subunit mediates Lana-1-induced serum response element activation.[Lana-1] (Mus musculus) PubMed

 5900.

C. neoformans Rim101 is also activated by the cAMP/PKA pathway [Rim101] (Mus musculus) PubMed

 5901.

Rice (Oryza sativa L.) has a plant-type phosphoenolpyruvate carboxylase, Osppc4, that is targeted to the chloroplast.[Osppc4] (Mus musculus) PubMed

 5902.

Trypanosoma cruzi calreticulin interacts in vitro with both solid phase bound active C1s and C1.[calreticulin] (Mus musculus) PubMed

 5903.

we describe the purification and characterization of PfSIP2, a member of the ApiAP2 family of putative transcription factors, as the unknown nuclear factor interacting specifically with cis-acting SPE2 motif arrays in subtelomeric domains. (Mus musculus) PubMed

 5904.

Characterization of a single-thioredoxin (Trx) QSOX shows strong similarities with the double-Trx enzymes investigated so far; lack of a second Trx domain does not result in major changes in QSOX catalytic specificity.[quiescin sulfhydryl oxidase; QSOX] (Mus musculus) PubMed

 5905.

CaMKII binding and phosphorylation sites on beta(2a) are concise but pivotal components of a molecular and biophysical and mechanism for early afterdepolarizations and impaired survival in adult cardiomyocytes.[CamKII, Cav1.2beta] (Mus musculus) PubMed

 5906.

Study shows that Galphai2 function is mediated by its interaction with GDE2, a known regulator of motor neuron differentiation, and that disruption of the GDE2/Galphai2 complex in vivo causes motor neuron deficits analogous to Galphai2 ablation.[Galphai2] (Mus musculus) PubMed

 5907.

Hpa is a novel harpin with two heptads for hypersensitive response. [Hpa] (Mus musculus) PubMed

 5908.

compelling evidence that CueO is a cuprous oxidase [CueO] (Mus musculus) PubMed

 5909.

In the present study, the authors confirm the specific binding of NS5B to one of the RNA stem-loop structures in the region, 5BSL3.2. (Mus musculus) PubMed

 5910.

Employing the new technique of analytical ultracentrifugation with fluorescence detection we have, for the first time, shown that the K(D)(4-2) for Ec-PK1 is in the subnanomolar range, well below the concentrations used in kinetic studies. (Mus musculus) PubMed

 5911.

PrtV protease has a role in Vibrio cholerae cytolysin-induced inflammatory response in human intestinal epithelial cells [PrtV] (Mus musculus) PubMed

 5912.

results suggest that, in Synechocystis cells, RNA helicase CrhR regulates the low-temperature inducibility of molecular chaperonins GroES, GroEL1 and GroEL2, which are, in turn, essential for growth at low temperatures [CrhR] (Mus musculus) PubMed

 5913.

evidences for intragenic recombination in PvMsp-5 were found in most populations except that from southern Thailand in which haplotype diversity and nucleotide diversity were exceptionally low.[merozoite surface protein-5] (Mus musculus) PubMed

 5914.

Our data suggest a host-specific factor is required for efficient folding of plasmid-encoded toxin.[plasmid-encoded toxin] (Mus musculus) PubMed

 5915.

a cell model with DC-SIGN transient transfection to study p38 mitogen-activated protein kinase (MAPK) signaling pathway in response to the E2 treatment [hepatitis C virus E2] (Mus musculus) PubMed

 5916.

Substrate selectivity of glycerol-3-phosphate acyltransferase (EC 2. 3. 1. 15) of rice (Oryza sativa L.) was explored in a comparative study of acyltransferases from seven plant species.[GPAT] (Mus musculus) PubMed

 5917.

significant differences between the human and Plasmodium dUTPases [dUTPase] (Mus musculus) PubMed

 5918.

The SAP domain is required for association of XDppa2/4 to chromatin and for embryonic survival at later stages of development suggesting epigenetic programming events.[XDppa2/4] (Mus musculus) PubMed

 5919.

The characterization of an NAD(+)-dependent and zinc containing alcohol dehydrogenase (ADH) from Thermus thermophilus (TTHADH) is described.[TTADH] (Mus musculus) PubMed

 5920.

The experimental data support the idea that transmembrane proximal region of E1 might be involved in membrane destabilization and viral fusion.[E1 glycoprotein] (Mus musculus) PubMed

 5921.

The interaction of two helical antimicrobial peptides, HPA3 and HPA3P, derived from RpL1, with planar supported lipid membranes was quantitatively analysed using two complementary optical biosensors.[RpL1] (Mus musculus) PubMed

 5922.

We present soluble overexpression and molecular characterization of Aga50D. It had unique exo-lytic activity and was able to produce neoagarobiose directly from agarose. [Aga50D] (Mus musculus) PubMed

 5923.

ERK1 - sequence and expression analysis (Mus musculus) PubMed

 5924.

We identified a response regulator, VemR, that regulates Xcc pathogenesis. [VemR] (Mus musculus) PubMed

 5925.

Overexpression of OsRAN2 in rice resulted in enhanced sensitivity to salinity, osmotic stress, and abscissic acid.[OsRAN2] (Mus musculus) PubMed

 5926.

Our results show that ADE8 (encoding phosphoribosylglycinamide formyl-transferase) and GUA1 (GMP synthase) genes involved in purine biosynthesis are required for systemic candidiasis. [ADE8, GUA1] (Mus musculus) PubMed

 5927.

Molecular dynamics simulations of hexameric PNP from Plasmodium falciparum (PfPNP), is described.[PfPNP] (Mus musculus) PubMed

 5928.

C-terminal domain of the Pseudomonas aeruginosa OprM and the alpha-helical hairpin domain of Vibrio cholerae VceA play an important role in the assembly of a chimeric efflux pump.[VceA][VceB] (Mus musculus) PubMed

 5929.

Pf332 is a molecule with a potential role to support merozoite invasion. Due to the high level of conservation in sequence, the novel DBL-domain of Pf332 is of possible importance for development of novel anti-malaria drugs and vaccines [Pf332] (Mus musculus) PubMed

 5930.

report the high-resolution crystal structure of RrgA, a 893-residue elongated macromolecule whose fold contains four domains presenting both eukaryotic and prokaryotic origins. [RrgA] (Mus musculus) PubMed

 5931.

The SsrB-dependent regulon of ancestral and horizontally acquired genes, is described.[SsrA, SsrB] (Mus musculus) PubMed

 5932.

found that peptidoglycans derived from Gram-negative bacteria (Escherichia coli 0111:B4 and K12), are potent inducers of IL-1beta and IL-6 gene expression and were equal to, or more potent than, crude LPS.[IL-1beta] (Mus musculus) PubMed

 5933.

Varicella-zoster virus IE4 protein interacts with SR proteins and exports mRNAs through the TAP/NXF1 pathway [IE4] (Mus musculus) PubMed

 5934.

assessed distribution of the F290V resistant AChE1 in natural populations around the Mediterranean Sea; presence of duplicated alleles, associating a susceptible & a V copy of the ace-1 gene, was shown in most individuals analyzed for its presence [ace-1] (Mus musculus) PubMed

 5935.

Results describe the regulation of neuronal K(2P)2.1 (KCNK2, TREK-1) channel activity by resting membrane potential [KCNK2]. (Mus musculus) PubMed

 5936.

OsCSTLP1 has CMP-sialic acid transporter activity. On the other hand, OsCSTLP2 did not exhibit any nucleotide sugar transporter activity. [OsCSTLP1 and OsCSTLP2] (Mus musculus) PubMed

 5937.

We have cloned and expressed a short tyrosinase-like enzyme from A. oryzae lacking a C-terminal domain and classifed it a catchol oxidase since it lacked activity on tyrosine. [AoCO4] (Mus musculus) PubMed

 5938.

the CID1 C-type cyclin gene plays multiple roles in the regulation of vegetative growth, sexual development, conidiation, DON production, and pathogenicity [CID1] (Mus musculus) PubMed

 5939.

Study we show that the dst2-1 mutant exhibits a blind phenotype during asexual spore production in addition to that in fruiting-body photomorphogenesis and that dst2 is predicted to encode a protein with a putative FAD-binding-4 domain. (Mus musculus) PubMed

 5940.

data suggest that, by directly interacting with fibronectin, plasminogen- and fibronectin-binding protein B (PfbB) significantly increases the ability of S. pneumoniae to adhere to human epithelial cells [PfbB] (Mus musculus) PubMed

 5941.

Viral-derived membrane interacting peptides all act via a similar mechanism, which is substantially different from that of the non-cell selective lytic peptide melittin.[Glycoprotein B] (Mus musculus) PubMed

 5942.

Here, the authors show that ICP27 undergoes a head-to-tail intramolecular interaction but not head-to-tail or tail-to-tail intermolecular interactions.[ICP27] (Mus musculus) PubMed

 5943.

Data present a novel, plasma membrane-localized sucrose transporter (Srt1) from the corn smut fungus Ustilago maydis and its characterization as a fungal virulence factor. [Srt1] (Mus musculus) PubMed

 5944.

BmNOX is a secretory protein expressed heavily in the posterior mid gut, with weaker expression in the fore- and mid-gut regions [NADH-oxidoreductase-like protein, BmNox] (Mus musculus) PubMed

 5945.

Prolyl isomerase activity is located in a typical FKBP domain, whereas chaperone function is associated with the autonomously folded insert-in-flap (IF) domain.[SlyD] (Mus musculus) PubMed

 5946.

report the first crystal structures of Fis bound to high- and low-affinity 27-base-pair DNA sites [Fis] [no strain indicated] (Mus musculus) PubMed

 5947.

The results show that TaSnRK2.4 is involved in the regulation of enhanced osmotic potential, growth, and development under both normal and stress conditions.[TaSnRK2.4] (Mus musculus) PubMed

 5948.

The current knowledge about the structure and biosynthesis of PIA is summarized.[PIA] (Mus musculus) PubMed

 5949.

LepA is involved in co-translational folding of proteins that are otherwise vulnerable to tellurite oxidation [LepA] (Mus musculus) PubMed

 5950.

Ta-JA1 belongs to a mannose-specific lectin, which may confer a basal but broad-spectrum resistance to plant pathogens.[JA1] (Mus musculus) PubMed

 5951.

These data suggest that Orysa;KRP3 is involved in cell cycle control of syncytial endosperm.[Orysa;KRP3] (Mus musculus) PubMed

 5952.

the function of Nup98 extends beyond transport at the nuclear pore to include mRNA regulation in the cytoplasm [Nup98] (Mus musculus) PubMed

 5953.

Unlike other CREB2 (ATF4) proteins, the ATF4 isolated from the gonads of Xenopus embryos contains a consensus phosphorylation site for protein kinase A (PKA).[PKA] (Mus musculus) PubMed

 5954.

Depolarization increases phosphatidylinositol (PI) 4,5-bisphosphate level and KCNQ currents through PI 4-kinase mechanisms [KCNQ2 and KCNQ3] (Mus musculus) PubMed

 5955.

report the identification of a soluble form of the pilus protein FimA from the culture supernatants of E. coli K1, Salmonella, and Shigella that can potently inhibit Bax-mediated release of cytochrome c from isolated mitochondria.[FimA] (Mus musculus) PubMed

 5956.

For the first time, endogenous components of SCF (Cullin-1 and Skp1) were co-precipitated with Myxoma Nuclear factor, expressed in an infectious context, and without over-expression of any protein.[Myxoma Nuclear factor] (Mus musculus) PubMed

 5957.

LAT functions as an anti-apoptosis factor during HSV-1 infection. [LAT] (Mus musculus) PubMed

 5958.

The N-terminal domain of unliganded P3 is a tetrameric parallel coiled coil with a unique organization showing two successive four-stranded subdomains with opposite supercoiling handedness stabilized by a ring of interchain disulfide bridges.[P3] (Mus musculus) PubMed

 5959.

This study highlights the fact that interactions of M1 with viral envelope proteins are essential to direct M1 to the plasma membrane for influenza virus particle release. (Mus musculus) PubMed

 5960.

The authors showed that in addition to the E627K mutation, the influenza A virus PB2 mutation T271A enhances polymerase activity in human cells.[PB2] (Mus musculus) PubMed

 5961.

These findings suggest that furin or a furin-like proprotein convertase facilitates duck hepatitis B virus infection by cleaving both the docking receptor and the viral large envelope protein.[viral large envelope protein] (Mus musculus) PubMed

 5962.

report the identification of a soluble form of the pilus protein FimA from the culture supernatants of E. coli K1, Salmonella, and Shigella that can potently inhibit Bax-mediated release of cytochrome c from isolated mitochondria.[FimA] (Mus musculus) PubMed

 5963.

All the data suggest that Classical swine fever virus NS2 protein modulate the cellular growth and cell cycle progression through inducing the S-phase arrest and provide a cellular environment that is advantageous for viral replication.[NS2] (Mus musculus) PubMed

 5964.

structural modelling of the E. coli EfeO Cup domain identifies two potential metal-binding sites [EfeO] (Mus musculus) PubMed

 5965.

These data indicate that the m74 gene product together with other viral proteins codetermines CMV spread and CMV entry into cells.[M74] (Mus musculus) PubMed

 5966.

The isolation and characterization of 2 new alleles of merozoite surface protein alpha in P. vivax from Korean patients are reported. (Mus musculus) PubMed

 5967.

ManA transcription is positively regulated by Clp and RpfF and induced by locust bean gum. [ManA] (Mus musculus) PubMed

 5968.

we identified, SrcA, a multi-cargo secretion chaperone that is functionally integrated with the SPI-2-encoded type III secretion system and required for systemic infection in mice. (Mus musculus) PubMed

 5969.

TgMORN1 is required for maintaining the structural integrity of the parasite posterior end (Mus musculus) PubMed

 5970.

The mitogen-activated protein (MAP) kinase Hog1 controls CMV activation by osmotic stress through the ATF/CRE-related transcription factor Sko1 and the yeast osmostress factor Hot1.[Hot1, Sko1] (Mus musculus) PubMed

 5971.

RecA and the SOS response are required for a substantial fraction of thymineless death.[RecA] (Mus musculus) PubMed

 5972.

This study showed that E. coli could not enter the VBNC state in the lack of EnvZ product under the stress of osmolarity, pH and starvation and the relationship between EnvZ and VBNC state are not affected by pH, osmolarity and starvation.[EnvZ] (Mus musculus) PubMed

 5973.

IHF positions SmcR to contact RNAP by looping the vvpE regulatory DNA, thus allowing precise control of the expression level of VvpE during the pathogenesis of V. vulnificus [VvpE] (Mus musculus) PubMed

 5974.

Data demonstrated the binding of BeF3- to HpCheY1 and the interaction between BeF3--HpCheY1 and HpFliM. Comparison of the BeF3--HpCheY1 and BeF3--EcCheY structures revealed a distinctive FliM binding surface. [CheY1] (Mus musculus) PubMed

 5975.

Using a bioinformatic approach, we show that SporoSAG clusters with the SAG2 subfamily of the SAG1-related superfamily (SRS) and is non-polymorphic among the 11 haplogroups. (SporoSAG) (Mus musculus) PubMed

 5976.

6S RNA -35 binding to sigma(70) RNA polymerase holoenzyme can regulate expression from "strong" and "weak" -35 DNA promoters and 6S RNA release rates may have been fine tuned during evolution to correctly regulate cellular levels of transcription (6S RNA) (Mus musculus) PubMed

 5977.

xlEPO shares structural and functional similarities and differences with mammalian counterparts, and regulation of xlEPO expression and its influence on the erythropoietic system appears to be unique. EPO. (Mus musculus) PubMed

 5978.

show that Xenopus Bsx (Xbsx) is expressed rhythmically in postmitotic photoreceptor precursors, reaching a peak during the night, with a cycle that is complementary to the daily rhythms of S-phase entry displayed by pineal cells.[ Bsx ] (Mus musculus) PubMed

 5979.

The relevance of CdpA in Burkholderia pseudomallei virulence was demonstrated by a 3-fold reduction in invasion of human lung epithelial cells and a 6-fold reduction in cytotoxicity on human macrophage cells infected with the cdpA mutant.[cdpA] (Mus musculus) PubMed

 5980.

These results suggest ERK1 and ERK2 have different roles in G protein-mediated signaling during growth and development.[ERK1, ERK2] (Mus musculus) PubMed

 5981.

The authors found that an amphipathic helix located within the M2 cytoplasmic tail is able to bind cholesterol, and they speculate that M2 cholesterol binding is essential for both filament formation and the stability of existing viral filaments. (Mus musculus) PubMed

 5982.

Ser/Thr phosphorylation by PknB/Stk and dephosphorylation by Stp play an important role in central metabolic processes such as cell wall metabolism, glycolysis, citrate cycle, purine-, pyrimidinesynthesis, and translation. [REVIEW/Stk/PknB/Stp] (Mus musculus) PubMed

 5983.

Changes in pulmonary alveolar ultrastructure and decreased expression of SP-A occur in fetal rabbits after intrauterine infection. [surfactant protein A] (Mus musculus) PubMed

 5984.

The results indicated that the MPR300 in chicken embryo fibroblasts cells plays a key role in sorting and trafficking of these soluble hydrolases.[MPR300] (Mus musculus) PubMed

 5985.

study demonstrates that the deviation from Michaelis-Menten behavior for GpdQ at lower pH when bpNPP is the substrate is due to the sequential hydrolysis of both bpNPP and its monoester product pNPP [Glycerophosphodiesterase (GpdQ)] (Mus musculus) PubMed

 5986.

These results indicate that stringent conditions are present during infection and that RSH-dependent derepression of CodY-regulated genes is essential for virulence in Staphylococcus aureus.[RSH] (Mus musculus) PubMed

 5987.

Controlling the temperature and pH of KcsA samples produced three distinct methyl-TROSY and NOESY spectra, corresponding to the resting, activated, and inactivated states. [KcsA] (Mus musculus) PubMed

 5988.

Incubation with lipopolysaccharides did not affect the binding of the B-subunits of heat-labile enterotoxin of human isolates to blood group A-carrying glycosphingolipids.[heat-labile enterotoxin] (Mus musculus) PubMed

 5989.

These results demonstrate that deglycosylation of a human serum glycoconjugate(s) by the combined effects of NanA, BgaA, and StrH, is important for resistance to complement phagocytic killing of Streptococcus pneumoniae.[BgaA & StrH] (Mus musculus) PubMed

 5990.

The logarithm of the catalytic efficiency for R274N/R276N, log(k(cat)/K(m)) exhibited the best linear correlation with the heat-denaturation temperature midpoint of the corresponding acylated complex of E166A/R274N/R276N. (beta-lactamase Toho-1) (Mus musculus) PubMed

 5991.

Tax binds the cyclin D1 promoter-proximal cyclic AMP response element (CRE) in the presence of phosphorylated CREB (pCREB) in vitro, and together the Tax-pCREB complex recruits the cellular co-activator p300 to the promoter. (Mus musculus) PubMed

 5992.

The data suggest that centromeric RNA helps to recruit CENPC to the inner kinetochore by altering its DNA binding characteristics.[CENPC] (Mus musculus) PubMed

 5993.

Slit acts via Robo2 in dendrites as a branching/growth factor but not in guidance, while Robo2 and Robo3 function in concert in axons to mediate axonal interactions and respond to Slits as guidance factors [Robo2] (Mus musculus) PubMed

 5994.

Identified are two independent sites in tubulin, which are critical for kinesin motility. [kinesin] (Mus musculus) PubMed

 5995.

FRH has a role in regulating the phosphorylation and stability of Neurospora circadian clock protein FRQ [FRH] (Mus musculus) PubMed

 5996.

The authors observed that the putative Staphylococcus saprophyticus virulence factors Ssp and SdrI were important for persistence, but not for initial colonization, in the murine urinary tract.[Ssp & SdrI] (Mus musculus) PubMed

 5997.

TgMYST-B is a MYST family lysine acetyltransferase that facilitates ataxia telangiectasia mutated (ATM) kinase-mediated DNA damage response in Toxoplasma gondii [MYST-B] (Mus musculus) PubMed

 5998.

These results demonstrated that the expression of GRA1 in ER of macrophages promotes both growth and adherence of macrophages and modulates the intracellular calcium release stimulated by arachidonic acid [GRA1] (Mus musculus) PubMed

 5999.

E. coli DUF299 catalyzes both the ADP-dependent inactivation and the Pi-dependent activation of Phosphoenolpyruvate synthetase (DUF299). (Mus musculus) PubMed

 6000.

The virulence of the sspA(-) mutant was markedly lower than the wild type in pigs as demonstrated in experimental infections.[sspA] (Mus musculus) PubMed

 6001.

Microarrays confirmed the global regulatory role of SpxA and SpxB. SpxB had a secondary role in regulation of oxidative stress genes but appeared to play a larger role in controlling processes associated with cell wall homeostasis. [SpxB] (Mus musculus) PubMed

 6002.

The authors identify and characterize a Cryptococcus neoformans homolog of the Saccharomyces cerevisiae BIM1 gene, and establish the importance of BIM1 for proper filamentous growth of Cryptococcus neoformans.[BIM1] (Mus musculus) PubMed

 6003.

These results indicate that selective binding of gp82 to gastric mucin may direct Trypanosoma cruzi metacyclic trypomastigotes to stomach mucosal epithelium in oral infection. (Mus musculus) PubMed

 6004.

The structure of the 3' region of the cagA gene in Helicobacter pylori isolated from an Iranian population was Western type. (Mus musculus) PubMed

 6005.

data identify SAND-1 (Mon1) and CCZ-1 (Ccz1) as critical and evolutionarily conserved components regulating the processing of ingested apoptotic cell corpses [CCZ-1] (Mus musculus) PubMed

 6006.

The association between daily cotrimoxazole-prophylaxis and infection with P. falciparum containing mutations in the dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) genes among HIV patients is reported.[DHFR; DHPS] (Mus musculus) PubMed

 6007.

The results of surveillance for mutations in dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhps)in P. falciparum during introduction of artesunate-cotrimoxazole combined therapy in Mozambique are reported.[DHFR; DHPS] (Mus musculus) PubMed

 6008.

Two novel tachykinin-like peptides named tachykinin-DR1 and -DR2 were identified from skin secretions of Danio rerio [tachykinin-DR1 and tachykinin-DR2] (Mus musculus) PubMed

 6009.

Stromal processing peptidase is essential for chloroplast biogenesis at the early growth stage and for rice root development. [SPP] (Mus musculus) PubMed

 6010.

These results suggest that some protein fragments of CLAG-9 may be part of the molecular machinery used by malaria parasites to invade erythrocytes.[CLAG-9] (Mus musculus) PubMed

 6011.

Data demonstrate that there is no competition for actin-binding between PfEMP3 and Pf332, suggesting that they bind to different target sequences in actin [Pf332]. (Mus musculus) PubMed

 6012.

Leak K(+) channels (TASK-1) seem to be importantly involved in the initiation of the oxygen sensing mechanisms of the rabbit carotid body.[TASK-1] (Mus musculus) PubMed

 6013.

These results suggest that SaHPF is a key protein involved in 100S ribosome formation in S. aureus.[SaHPF] (Mus musculus) PubMed

 6014.

Mutagenesis and spectroscopic analyses were performed to identify the heme axial ligands in HtsA and to characterize axial mutants of HtsA [HtsA] (Mus musculus) PubMed

 6015.

The crystal structures of Get3 in ADP-bound and nucleotide-free forms at 3.0 A and 2.8 A resolutions, respectively, are reported.[Get3] (Mus musculus) PubMed

 6016.

The white-collar complex is the key element for con-10 activation.[Con-10] (Mus musculus) PubMed

 6017.

EBNA1 inhibits the canonical NF-kappaB pathway in carcinoma lines by inhibiting the phosphorylation of IKKalpha/beta.[EBNA1] (Mus musculus) PubMed

 6018.

Changes in the expression of Sema3A in spinal cord and NP-1 in L6 dorsal root ganglion after partial root rhizotomy may be involved in collateral sprouting of spared root in superficial lamina. [Sema3A; NP-1] (Mus musculus) PubMed

 6019.

The first structure of a pneumococcal autolysin, that of the LytC lysozyme, has been solved in ternary complex with choline and a pneumococcal peptidoglycan (PG) fragment. (Mus musculus) PubMed

 6020.

crystal structure of the N-terminal domain of Encephalitozoon cuniculi Cdc27 reveals a homo-dimeric structure, composed predominantly of successive TPR motifs [Cdc27, Apc3] (Mus musculus) PubMed

 6021.

These results indicated that SigN was involved in morphological development, secondary metabolism and stress responses in Streptomyces coelicolor.[SigN] (Mus musculus) PubMed

 6022.

[env glycoprotein] An immunodominant peptide derived from West Nile virus (WNV) envelope glycoprotein is paired with HLA-A*0201 trimer in a vaccine model that elicits a robust epitope-specific CD8+ T cell cytotoxic response against lethal WNV infection. (Mus musculus) PubMed

 6023.

These results indicate a possible role for Hwp2 in adhesion and invasiveness.[Hwp2] (Mus musculus) PubMed

 6024.

The pvmdr1 analysis revealed the existence of single (85.7%) and double (14.3%) mutant haplotypes (Mus musculus) PubMed

 6025.

(adrenergic alpha1L receptor) A typical alpha1L adrenoceptor phenotype with extremely low affinity for prazosin is exclusively expressed in the iris of pigmented rabbits. (Mus musculus) PubMed

 6026.

Ifr1 restores fertility through reducing either the transcription rate of B-atp6-orf79 or the stability of its primary transcripts. (Mus musculus) PubMed

 6027.

Both OsRR3 and OsRR5 mainly act as negative regulators of cytokinin signaling.[OsRR3, OsRR5] (Mus musculus) PubMed

 6028.

There was a significant difference in the prevalence of each MSP1 allelic variant both between age-groups and between the various categories of anaemia considered (P<0.0001 for each), with the highest number of alleles occurring in severe anaemia. (Mus musculus) PubMed

 6029.

The result confirms that PglB is solely responsible for the oligosaccharyltransferase activity and complements the finding that PglB exhibits relaxed sugar substrate specificity.(PglB) (Mus musculus) PubMed

 6030.

ERAP32 and ERAP18 are trypanosome-specific ER-localized proteins with a major role in VSG protein export [ERAP32, ERAP18] (Mus musculus) PubMed

 6031.

BICP27 shuttles between the nucleus and the cytoplasm by the functional nuclear export signal and nuclear localization signal through a CRM1-dependent nuclear export pathway and a Ran dependent nuclear import pathway.[BICP27] (Mus musculus) PubMed

 6032.

Sequence analysis of 3a and 3b genes of Chinese field strains showed that the strains were genetically diverse among themselves as well as in comparison with reference strains. [3a protein, 3B protein] (Mus musculus) PubMed

 6033.

The CYP102B1 fatty acid hydroxylase metabolism of arachidonic acid produced 11,12-epoxyeicosa-5,8,14-trienoic acid in addition to 18-hydroxy arachidonic acid and 14,15-epoxyeicosa-5,8,11-trienoic acid.[CYP102B1] (Mus musculus) PubMed

 6034.

the ultra-weak photon emission of the E. coli with and without the Yhha gene (Mus musculus) PubMed

 6035.

CLP24 is a novel regulator of VEGFR-2 and VEGFR-3 signaling pathways and of normal lymphatic vessel structure [Claudin-like protein of 24 kDa (CLP24)] (Mus musculus) PubMed

 6036.

The isoforms of Xenopus Cdc4,xCdc4alpha is found to be dynamically expressed throughout early Xenopus development, with particular enrichment in neural crest and neural crest-derived tissues. [xCdc4alpha] (Mus musculus) PubMed

 6037.

CLP24 is a novel regulator of VEGFR-2 and VEGFR-3 signaling pathways and of normal lymphatic vessel structure [Claudin-like protein of 24 kDa (CLP24)] (Mus musculus) PubMed

 6038.

cagA in situ expression is increased in H pylori-infected children with peptic ulcers and may play a role in the pathogenesis of peptic ulcer disease during childhood [cagA] (Mus musculus) PubMed

 6039.

"flipped" conformation of selectivity filter present in E71A allows weaker extracellular & stronger intracellular TEA binding, whereas higher PG content decreases channel conductivity and stabilizes the channel open "flipped" state[KcsA] (Mus musculus) PubMed

 6040.

Study demonstrated that Cul4 and DDB1 are associated with the histone methyltransferase DIM-5 protein and are essential for DNA methylation in vivo. [Cul4] (Mus musculus) PubMed

 6041.

Solved is the structure of the autoinhibited (apo) and activated (calcium-bound) conformation of calcium-dependent protein kinase from the apicomplexan parasite Toxoplasma gondii.[calcium-dependent protein kinase] (Mus musculus) PubMed

 6042.

Neurospora PARP orthologue (NPO) may regulate aging by impacting NAD+/NAM availability, thereby influencing Sirtuin activity, or they may function in alternative NAD+-dependent or NAD+-independent aging pathways.[NPO] (Mus musculus) PubMed

 6043.

Results indicate that NrdB protein, and most likely RNR protein, is closely linked to the replication proteins or replisome at the replication fork ( NrdB ). (Mus musculus) PubMed

 6044.

These data indicate that the Aspergillus oryzae PlaA and PlaB secretory phospholipase enzymes display distinct, presumably non-redundant, physiological functions.[PlaB] (Mus musculus) PubMed

 6045.

The study shows the crystal structure of the reduced form of R. marinus high-potential iron-sulfur protein (HiPIP) solved by the single-wavelength anomalous diffraction method,refined to 1.0 A resolution.[high-potential iron-sulfur protein] (Mus musculus) PubMed

 6046.

These results collectively suggest that AMA-1 displays high genetic polymorphism among Myanmar Plasmodium vivax isolates with highly diversifying selection at domain I.[AMA-1] (Mus musculus) PubMed

 6047.

Variance of vacA genotypes of local H. pylori isolates mainly lied in mid-region.[VacA] (Mus musculus) PubMed

 6048.

Our discovery of previously undocumented nonfunctional phr1 alleles suggests that there are likely to be other loss-of-function mutations segregating in Oryza sativa around the world. [Phr1 protein, Oryza] (Mus musculus) PubMed

 6049.

Yeast two-hybrid analysis revealed that the full-length PTP1, PTP2 and PTP3 proteins of Encephalitozoon cuniculi interact with each other in vivo.[PTP1 , PTP2 and PTP3] (Mus musculus) PubMed

 6050.

E2F5 may play important roles in zebrafish brain, eye and ovarian development.[zE2F5a and zE2F5b] (Mus musculus) PubMed

 6051.

The ancient OsMADS6 gene is able to specify "floral state" by determining floral organ and meristem identities in monocot crop rice. (Mus musculus) PubMed

 6052.

The authors showed that Hp-DcuA, the fourth component of these novel deamidase-transport systems, was as crucial as Hp-gammaGT, Hp-AnsB, and Hp-GltS for animal model colonization.[AnsB] (Mus musculus) PubMed

 6053.

find that two knotted methyltransferases, YibK and YbeA, can exist in a trefoil-knot conformation even in their chemically unfolded states.[YibK] (Mus musculus) PubMed

 6054.

The crystal structure of Plasmodium falciparum D-tyrosyl-tRNATyr deacylase was determined using the iodide-SAD phasing method.[D-tyrosyl-tRNATyr deacylase] (Mus musculus) PubMed

 6055.

H. pylori is likely to adhere to the gastric mucosa with sialic acid binding adhesin(SabA). Expression is frequently switched "on" or "off", suggesting that SabA expression can rapidly respond to changing conditions in the stomach. [REVIEW] (Mus musculus) PubMed

 6056.

The TBF1 protein of Saccharomyces cerevisiae is required for full snoRNA expression, yet it does not influence nucleosome positioning at snoRNA promoters. (Mus musculus) PubMed

 6057.

Intersubunit electrostatic interaction among Glycine Receptor subunits contributes to the stabilization of the closed channel state, and its disruption represents a critical step in GlyR activation. [GlyR-alpha] (Mus musculus) PubMed

 6058.

The crystal structure of release factor 2 bound to ribosome with an aminoacyl tRNA substrate analog at the ribosomal P site, at 3.1 A resolution, is reported.[release factor 2] (Mus musculus) PubMed

 6059.

Strains with a deletion of vttR(A) or vttR(B) showed attenuated colonization in vivo, indicating that the type three secretion system -encoded regulatory proteins play a role in virulence.[vttR(A), vttR(B)] (Mus musculus) PubMed

 6060.

The CvfA-enolase complex in Streptococcus pyogenes is involved in the regulation of virulence gene expression by controlling RNA degradation according to nutritional stress. (Mus musculus) PubMed

 6061.

The study shows the crystal structure of the Sac phosphatase domain of yeast Sac1.[Sac1] (Mus musculus) PubMed

 6062.

Formation of the genetically transmissible prion state is a two-step process that involves an ancient system for the asymmetric inheritance of damaged proteins and heritable changes in the extent of prion fragmentation.[Sup35] (Mus musculus) PubMed

 6063.

A systematic analysis of Magic-angle spinning (MAS) solid-state NMR protein spectra for two protein systems--GB1, a 6 kDa nanocrystalline protein and DsbA, a 21 kDa nanocrystalline protein, are presented.[DsbA] (Mus musculus) PubMed

 6064.

A map-based cloning approach pinpointed an Ostetratricopeptide repeat (TPR) as a strong candidate of FLO(a) and the proteins that contain TPR motifs might play a significant role in rice starch biosynthetic pathways.FLO(a) (Mus musculus) PubMed

 6065.

a TFA-type zinc finger protein gene ZFP207 (GenBank assession number AK063147.1) was cloned from rice variety Jiucaiqing by RT-PCR approach.[ZFP207] (Mus musculus) PubMed

 6066.

The crystal structure of Salmonella FliT at 3.2-A resolution, is reported.[FliT] (Mus musculus) PubMed

 6067.

The anterior expression is not fixed in the period of limb development, but the expression domains of Mkp3, Sef and TSK change considerably from the distal domain to the anterior domain [Mkp3] (Mus musculus) PubMed

 6068.

H. pylori urease may exist in aggregated and dissociated forms, each with intact function but differing kinetics that may be of importance in maximizing urea breakdown at varying urea concentrations in vivo. [Urease/ H. pylori ATCC 49503] (Mus musculus) PubMed

 6069.

The results suggested that SCO3900 encodes a negative regulator participating in morphological differentiation of Streptomyces coelicolor by influencing the expression of its downstream genes.[SCO3900] (Mus musculus) PubMed

 6070.

Igo1/2 may have an evolutionarily conserved role in fungal mRNA stability control. (Mus musculus) PubMed

 6071.

The detailed location of a low-tillering gene, Ltn, which has been localized on chromosome 8 in Aikawa 1, was confirmed by molecular mapping.[Ltn] (Mus musculus) PubMed

 6072.

high-resolution solution NMR spectra of OmpX kept water-soluble by either amphipol A8-35 or the detergent dihexanoylphosphatidylcholine. (Mus musculus) PubMed

 6073.

Data demonstrates that the RNA recognition motif of Rna15 displays a strong preference for GU-rich RNA, mediated by a binding pocket that is entirely conserved in both yeast and mammalian Rna15 orthologues (Rna15). (Mus musculus) PubMed

 6074.

This study concluded that further work should be performed to elucidate the role of platelet activating factor (PAF) in the pathophysiology of inflammatory airway disease.[PAF] (Mus musculus) PubMed

 6075.

These results demonstrated that the PmrAB system in Erwinia amylovora renders the pathogen more susceptible to polymyxin B and acidic pH, but more resistance to excess iron.[PmrA & PmrB] (Mus musculus) PubMed

 6076.

RamR mutation and presence of plasmid borne tet(A)variant assoaciated with TN 1721 in A clinical isolate Salmonella enterica serovar Hadar resistant to tigecylcine. [ramR, tet(a)] (Mus musculus) PubMed

 6077.

The function of MukB hinge appears to be limited to dimerization of two copies of MukB molecules.[MukB] (Mus musculus) PubMed

 6078.

Follow-up of the mutant clone that was most heavily impaired in biofilm formation led to the identification of a novel 285 kDa multi-domain protein which the authors have termed biofilm-promoting factor A (BpfA).[BpfA] (Mus musculus) PubMed

 6079.

Pup1 has the potential to improve yield in phosphorus-deficient and/or drought-prone environments and in diverse genetic backgrounds.[Pup1] (Mus musculus) PubMed

 6080.

Down-regulation of S-adenosyl-methionine-decarboxylase (AdoMETDC) inhibited hypusine biosynthesis. [AdoMETDC] (Mus musculus) PubMed

 6081.

CagA protein negatively regulates the functions of DC via CagA phosphorylation and that cagA-positive H. pylori strains suppress host immune responses resulting in their chronic colonization of the stomach. (Mus musculus) PubMed

 6082.

A model for HpNikR activation involves a first activation step where occupancy of the high-affinity site establishes a hydrogen bond network required for DNA binding. (Mus musculus) PubMed

 6083.

Suppression of rpS3a caused by RNAi did not permanently block ovarian development. [RpS3a] (Mus musculus) PubMed

 6084.

zfMC2R is not functional in the absence of MRAP expression.[MRAP1, MRAP2a, MRAP2b] (Mus musculus) PubMed

 6085.

These data indicate that the galU gene contributes to Xanthomonas citri subsp. citri growth in intercellular spaces and is involved in extracellular polysaccharides and capsular polysaccharide synthesis and biofilm formation. (Mus musculus) PubMed

 6086.

found that DIM-7 is essential for recruitment of DIM-5 to form heterochromatin.[DIM-7] (Mus musculus) PubMed

 6087.

higher-level thymidine phosphorylase expression is correlated with LMP1 positivity in NPC biopsy samples (LMP1). (Mus musculus) PubMed

 6088.

FtsK trimers with a single catalytic mutation give translocases impaired in displacing a DNA roadblock. [FtsK] (Mus musculus) PubMed

 6089.

Complete data sets were collected to 1.5 and 1.4 A resolution, respectively, from single crystals of DdlB under cryogenic conditions using synchrotron radiation.[DdlB] (Mus musculus) PubMed

 6090.

Results show that NRL1 gene was mapped to chromosome 12 and encodes the cellulose synthase-like protein D4 (OsCslD4): [NRL1] (Mus musculus) PubMed

 6091.

The 36.5 kDa m164 gene product is identified here as an integral type-I membrane glycoprotein trafficking within the endoplasmic reticulum (ER) and outer nuclear membrane with an high lateral membrane motility. (Mus musculus) PubMed

 6092.

Crystals of apo Dictyostelium discoideum phenylalanine hydroxylase (DicPAH; residues 1-415) and the DicPAH-dihydrobiopterin-Fe(III) complex diffracted to 2.6 and 2.07 A resolution. [phenylalanine hydroxylase ] (Mus musculus) PubMed

 6093.

The 480-kDa complex contributes to template-dependent RdRP activities. [RdRP] (Mus musculus) PubMed

 6094.

TrwB has a role in recognizing G-quadruplex structures as loading sites on the DNA [TrwB] (Mus musculus) PubMed

 6095.

The oral administration of the expressed alpA induced protective immunity in mice. [alpA] (Mus musculus) PubMed

 6096.

These results indicate that GlxR plays an important role in carbon catabolite repression as well as in acetate metabolism.[GlxR] (Mus musculus) PubMed

 6097.

cytochrome P450 gene has been isolated from the insecticide-susceptible strain of the red flour beetle, Tribolium castaneum (Herbst) and the nucleotide sequence determined. [CYP345D3 ] (Mus musculus) PubMed

 6098.

The gene coding for rice chloroplastic L-myo-inositol-1-phosphate synthase (MIPS; EC 5.5.1.4) has been identified.[MIPS] (Mus musculus) PubMed

 6099.

exoerythrocytic P. berghei parasites express a potent cysteine protease inhibitor (PbICP) which has an important function in sporozoite invasion and is capable of blocking hepatocyte cell death[PBICP] (Mus musculus) PubMed

 6100.

The changes of HSP 70 mRNA and c-fos mRNA expression in skeletal muscle and cardiac muscle can be used as an indicator to distinguish antemortem from postmortem electrocution. [HSP70; c-fos] (Mus musculus) PubMed

 6101.

One fur mutant was attenuated on a host plant, thus indicating that fur has important roles in the virulence of Xanthomonas campestris pv. campestris.[fur] (Mus musculus) PubMed

 6102.

Hydrophobicity of the VP5 is required for membrane disruption during rotavirus cell entry. [VP5] (Mus musculus) PubMed

 6103.

CaPTC6 is the functional homologue of Saccharomyces cerevisiae PTC6. [PCT6] (Mus musculus) PubMed

 6104.

CaPTC6 is the functional homologue of Saccharomyces cerevisiae PTC6. [PCT6] (Mus musculus) PubMed

 6105.

ZmPIN1 proteins are polarly localized in the embryo cell plasma membrane from the first developmental stages, indicating the existence of ZmPIN1-mediated auxin fluxes. [PIM1] (Mus musculus) PubMed

 6106.

low-density lipophorin (LDLp), results suggest that LDLp is required for the delivery of lipids for organogenesis during embryogenesis. (Mus musculus) PubMed

 6107.

Ppd-D1 haplotypes in 492 wheat varieties from diverse geographic locations and 55 accessions were identified.[Ppd-D1] (Mus musculus) PubMed

 6108.

MtMSBP1 is critical for mycorrhiza development.[MtMSBP1] (Mus musculus) PubMed

 6109.

It was concluded that Ku86 deficiency accelerates high NaCl induced cellular senescence in cultured cells, C. elegans, and knockout mouse kidney.[KU86] (Mus musculus) PubMed

 6110.

findings are consistent with the idea that the N-terminal domain of Kdo transferase may bind the acceptor lipid substrate, whereas the C-terminal domain binds the donor nucleotide (Kdo transferase) (Mus musculus) PubMed

 6111.

NMR characterization of the interaction of the Salmonella type III secretion system protein SipD and bile salts (Mus musculus) PubMed

 6112.

findings are consistent with the idea that the N-terminal domain of Kdo transferase may bind the acceptor lipid substrate, whereas the C-terminal domain binds the donor nucleotide (Kdo transferase) (Mus musculus) PubMed

 6113.

In wt & RIC1 cells, gammaH2AX foci formed after gamma-irradiation, but they disappeared more quickly in the RIC1 cells. Instability of gammaH2AX foci in RIC1 cells cause an aberration of the DNA damage response. RIC1 (Mus musculus) PubMed

 6114.

amphioxus SARM appears unique in that it may play dual functions in neural development and innate immunity by targeting amphioxus TLR signaling. (Mus musculus) PubMed

 6115.

Mgm1p mediates fusion through oligomerization, GTP hydrolysis, and lipid binding in a manner similar to those of other dynamin mechanoenzymes.[Mgm1p] (Mus musculus) PubMed

 6116.

transcriptional factor UreR is involved in the temperature dependency of urease activity, two nucleotides within the ureR promoter region are of particular importance for the urease activity dependency [UreR/Urease/V parahaemolyticus TH3996 and AQ4673] (Mus musculus) PubMed

 6117.

These results indicate the existence of a conformationally well-defined heme pocket that involves amino acids located in the proximity of H130, of CcmE.[CcmE] (Mus musculus) PubMed

 6118.

These results show that the type II thioesterase evolves its distinctive ability to recognize the aberrant intermediates from the versatile catalytic platform of hotdog proteins.[EntH] (Mus musculus) PubMed

 6119.

Hsp30 is necessary during lethal heat stress.[Hsp39] (Mus musculus) PubMed

 6120.

structures revealed the mode of binding of Rap1 and TFIIA to TFIID, as well as a reorganization of TFIIA induced by its interaction with Rap1 [TFIIA, Rap1, TFIID; strain not specified] (Mus musculus) PubMed

 6121.

Site-directed mutagenesis of residues in the BC loop (residues 329-333) of the envelope (E) protein domain III in a West Nile virus demonstrated a critical role for residues in this loop in the function and antigenicity of the E protein.[E] (Mus musculus) PubMed

 6122.

NMR relaxation studies of an RNA-binding segment of the rous sarcoma virus gag polyprotein in free and bound states: a model for autoinhibition of assembly (Mus musculus) PubMed

 6123.

HBZ is encoded on the proviral antisense & transcribed from a promoter in the 3' LTR. It inhibits expression of the other viral proteins by blocking the interaction of Tax & ATF/CREB & the recruitment of CBP/p300 by Tax on the promoter. HBZ. (Mus musculus) PubMed

 6124.

The authors show that P34 is a sequence non-specific single-stranded RNA-binding protein in vitro.[P34] (Mus musculus) PubMed

 6125.

Duplicated pair of GIF1 and OsCIN1 has experienced sub-functionalization that selection acts independently on each duplicate towards different functional specificity. [GIF1, CIN1] (Mus musculus) PubMed

 6126.

Biallele and triallele polymorphism of phosphoglucomutase locus was determined [phosphoglucomutase] (Mus musculus) PubMed

 6127.

MviN is regulated by LuxO and is involved in the pathogenicity. [MviN, LuxO] (Mus musculus) PubMed

 6128.

Data show that melatonin surges in the final stages of chick retinal cell differentiation in culture are essential for development of cells expressing alpha8 nAChR in full functional form [nAChR alpha8]. (Mus musculus) PubMed

 6129.

VacA p58 induced apoptosis in gastric epithelial carcinoma cells; apoptotic process is associated with the up-regulation of Bax/VDAC1 and downregulation of Bcl-2 [VacA] (Mus musculus) PubMed

 6130.

thermostability of CYP175A1 (Mus musculus) PubMed

 6131.

The authors demonstrated that GlnR and the GlnR box (ATGTNAN(7)TNACAT) were involved in the transcriptional repression of clusters of genes encoding proteins involved in glutamine and glutamate metabolism under acidic challenge.[GlnR] (Mus musculus) PubMed

 6132.

mga mutants displayed an increased attachment and internalization rate for eukaryotic cells.[mga] (Mus musculus) PubMed

 6133.

The study not only reveals the key structural elements and residues of sTrpRS involved in the recognition and binding of the ligands, but also provide new insights into the catalytic mechanism of Trp activation by eukaryotic TrpRSs (TrpRS). (Mus musculus) PubMed

 6134.

Metabolic control of vH(+)-ATPase involving regulation of its assembly state by elements of the glycolytic pathway could provide a means to adapt rumen epithelial cells ATP consumption according to energy availability.[vH(+)-ATPase] (Mus musculus) PubMed

 6135.

The authors show that expression of all genes of a gene cluster responsible for ustilagic acid biosynthesis depends on Rua1, a nuclear protein of the C(2)H(2) zinc finger family, whose gene is located within the gene cluster.[Rua1] (Mus musculus) PubMed

 6136.

The rpoX gene is involved in biofilm formation and stress response but the effects are controlled by colony phase variation in V. alginolyticus.[rpoX] (Mus musculus) PubMed

 6137.

Lack of Apobec2-related proteins causes a dystrophic muscle phenotype in zebrafish embryos (Mus musculus) PubMed

 6138.

The AceK structure reveals a eukaryotic protein-kinase-like domain containing ATP and a regulatory domain with a novel fold [aceK; no strain specified] (Mus musculus) PubMed

 6139.

RNAIII represses the synthesis of staphylocoagulase through a direct binding with the mRNA[RNAIII and staphylocoagulase] (Mus musculus) PubMed

 6140.

we report the high-resolution structure of the catalytically active amidase domain AmiE (amidase S. epidermidis) from the major autolysin of S. epidermidis[azutolysin] (Mus musculus) PubMed

 6141.

Snf1 modulates the level of eIF2alpha phosphorylation by different mechanisms, depending on the kind of nutrient deprivation existing in cells.[Snf1, Gcn2, Glc7, Sit4, eif2 alpha] (Mus musculus) PubMed

 6142.

prd-1 and prd-2 are good candidates for components of the FRQ-less oscillator and prd-3 and prd-4 act on the system mainly through effects on FRQ/WCC [prd-1,2,3,4] (Mus musculus) PubMed

 6143.

Increased iron and hydrogen peroxide concentrations decreased PerR binding to the promoter region of dpr, suggesting that regulation of Dpr by environmental signals is mediated by PerR directly.[PerR] (Mus musculus) PubMed

 6144.

nineteen different ms4760 microsatellite profiles of Pfnhe-1 were found including 14 not previously described; multivariate analysis showed no significant association between in vitro susceptibility to quinine with particular ms4760 profiles [Pfnhe-1] (Mus musculus) PubMed

 6145.

tryptophan oxygenase cDNA had 1374 nucleotides that encoded a 401 amino acid protein with an estimated molecular mass of 46.47 kDa and a PI of 5.88. [tryptophan oxygenase] (Mus musculus) PubMed

 6146.

These findings also identify survivin as a potential new target for the prevention of germ cell death during testicular torsion. (survivin) (Mus musculus) PubMed

 6147.

HrtA is responsible for increased expression of immunomodulatory factors and HrtB in absence of HrtA damages bacteria cell membrane by pore formation[HRTA AND HRTB] (Mus musculus) PubMed

 6148.

SPL28 encodes a clathrin-associated adaptor protein complex 1, medium subunit micro 1 (AP1M1), which is involved in the post-Golgi trafficking pathway. [SPL28] (Mus musculus) PubMed

 6149.

The roles of three actin cytoskeletal proteins, coronin, cofilin and Aip1 in actin dynamics by promoting or regulating disassembly, was examined.[Coronin1, Cofilin1, Aip1] (Mus musculus) PubMed

 6150.

The fbl gene was detected in all 17 Staphylococcus lugdunensis isolates examined. (Mus musculus) PubMed

 6151.

A naturally occurring missense polymorphism in WRN that interferes with helicase activity abolished its ability to restore top3 phenotype in sgs1 top3 S. cerevisiae.[SGS1; TOP3] (Mus musculus) PubMed

 6152.

Influenza A virus NS1 protein serves as a strong inducer of apoptosis in infected human respiratory epithelial cells and plays a critical role in disease pathogenesis.[NS1] (Mus musculus) PubMed

 6153.

Endogenous nitric oxide and carbon monoxide and mu3 receptors contribute to morphine-induced ocular hypotension. (mu3 receptor) (Mus musculus) PubMed

 6154.

The results of this study suggest for the first time that CYP1A may be implicated in the seawater acclimation of the gills of rainbow trout.[CYP1A] (Mus musculus) PubMed

 6155.

Cdc-25 family members function as distinct but related cell cycle regulators to control diverse cell cycles in C. elegans germline development. (Mus musculus) PubMed

 6156.

The data provide evidence for the presence of a cation-pi interaction between Arg58 of Ste2p and Tyr(13) of alpha-factor. [Ste2; alpha-factor] (Mus musculus) PubMed

 6157.

Activation of AKT and PKBR1 requires PDK1-site phosphorylation, but that phosphorylation by TORC2 is insufficient for AKT or PKBR1 activation.[AKT, PKBR1, PDK1, TORC2] (Mus musculus) PubMed

 6158.

the structure of HydA(DeltaEFG) (HydA expressed in a genetic background devoid of the active site H-cluster biosynthetic genes hydE, hydF and hydG) revealing the presence of a [4Fe-4S] cluster and an open pocket for the 2Fe subcluster [HydA] (Mus musculus) PubMed

 6159.

the results of studies silencing the expression of Sm-tsp-1 and Sm-tsp-2 mRNAs implied that tetraspanins play important structural roles impacting tegument development, maturation or stability (Mus musculus) PubMed

 6160.

results suggest a role for SFL2 in morphogenesis and an indirect role in C. albicans pathogenesis in epithelial tissues (SFL2). (Mus musculus) PubMed

 6161.

results suggest that C. albicans PEP12 plays a key role in biofilm integrity and in vivo virulence (PEP12). (Mus musculus) PubMed

 6162.

Sum1 functions as a key meiotic brake through the NDT80 promoter and that Cdk1 and Ime2 trigger exit from meiotic prophase by inhibiting the Sum1 transcriptional repression complex.[Cdk1, Ime2, Sum1] (Mus musculus) PubMed

 6163.

The authors show that both VP24 and VP40 regulate not only viral genome replication, but also transcription.[VP24 & VP40] (Mus musculus) PubMed

 6164.

Intracellular Ca(2+) is a parallel second messenger, by showing that agents that elevate intracellular Ca(2+) levels are potent STATc activators that stimulate phosphorylation of Serine 448 and Serine 747.[STATc] (Mus musculus) PubMed

 6165.

Within the intergenic region virA-icsA, a new gene was found that encodes a non-translated antisense RNA, transcribed in cis on the complementary strand of icsA (icsA). (Mus musculus) PubMed

 6166.

A homology model was constructed on the basis of the crystal structure of integron integrase VchIntIA from Vibrio cholerae bound to its cognate attC substrate VCRbs.[VchIntIA] (Mus musculus) PubMed

 6167.

The DNA bend angle (theta) depends on the TATA sequence, with theta for coreTBP and human TBP being greater than that for yeast TBP.[TBP] (Mus musculus) PubMed

 6168.

Assessment of Rot-dependent regulation of target genes revealed that Rot is a positive regulator of spa (protein A) transcription in all strains examined.[Rot] (Mus musculus) PubMed

 6169.

This study further established a link between salt and alkali stress and osa-MIR396c in rice.[MIR396c] (Mus musculus) PubMed

 6170.

The gene for epidermal cell differentiation inhibitor-B is part of a diverse pathogenicity island present in specific S. aureus clonal lineages. [EDIN-B] (Mus musculus) PubMed

 6171.

Sdo1p and SBDS may work to regulate Btn1p and CLN3, respectively (Sdo1p and Btn1p). (Mus musculus) PubMed

 6172.

Results suggest that CcCTR1 plays an important role in Cu accumulation in C. cinerea (CcCTR1). (Mus musculus) PubMed

 6173.

Esp hinders S. aureus colonization in vivo through a novel mechanism of bacterial interference, which could lead to the development of novel therapeutics to prevent S. aureus colonization and infection [Esp] (Mus musculus) PubMed

 6174.

eIF5 stabilizes the binding of GDP to eIF2 and is therefore a bi-functional protein that acts as a GDP dissociation inhibitor (GDI)[eIF5 = TIF5] (Mus musculus) PubMed

 6175.

The authors show that F18 associates with an A30-containing multiprotein complex in vivo in a manner that depends upon clusters of hydrophobic/aromatic residues in the N' terminus of the F18 protein.[F18] (Mus musculus) PubMed

 6176.

Epstein-Barr virus LMP1-mediated EGFR induction required the NF-kappaB-inducing kinase (NIK) but not the IkappaB kinase (IKK) complex components that regulate canonical or noncanonical NF-kappaB pathways.[LMP1] (Mus musculus) PubMed

 6177.

Hfq can form hexamers and to bind RNA molecules, and major role in the survival of Burkholderia cepacia under stress conditions. (Mus musculus) PubMed

 6178.

RASCAL and UL50 appeared to specifically interact, suggesting that RASCAL is a new component of the nuclear egress complex (NEC) and possibly involved in mediating nucleocapsid egress from the nucleus.[RASCAL] (Mus musculus) PubMed

 6179.

Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) is an essential regulator of calcium-dependent exocytosis in this opportunistic human pathogen [CDPK1] (Mus musculus) PubMed

 6180.

Our work demonstrates that although membrane insertion and folding of beta-barrel membrane proteins may be a cooperative process, the fragments can associate in vitro without any additional components.[OmpA] (Mus musculus) PubMed

 6181.

The relative contributions of CcrA and CcrB in the excision and integration of staphylococcal cassette chromosome mec(SCCmec).[CcrA; CcrB] (Mus musculus) PubMed

 6182.

BcCCC2 is necessary not only for penetrating a host but also for fungal growth within plant tissues [CCC2] (Mus musculus) PubMed

 6183.

Mei4 and Rec114, are evolutionarily conserved in most eukaryotes[Mei4] (Mus musculus) PubMed

 6184.

These data provide the first evidence that the capacity of the rabies virus P protein to inhibit STAT1 nuclear translocation and interferon signaling correlates with the viral pathogenicity.[P protein] (Mus musculus) PubMed

 6185.

The mask of the antigenic epitopes by 158N glycosylation at the HA globular head and its alpha2,3 sialoside binding preference of influenza A/Vietnam/1203/2004 (H5N1) vaccine virus affect virus antigenicity and replication in the host. (Mus musculus) PubMed

 6186.

the downstream step in this developmental signaling pathway as a DxDxT phosphatase, TbPIP39, which is activated upon tyrosine phosphorylation, and hence is negatively regulated by TbPTP1 (Mus musculus) PubMed

 6187.

The authors conclude that arginines at positions 138, 148, and 150 within the RGG box of ICP27 are required for binding to GC-rich sequences and that the N-terminal portion of ICP27 is highly flexible in structure.[ICP27] (Mus musculus) PubMed

 6188.

The D151G substitution was shown to cause a change in the specificity of NA such that it acquired the capacity to bind receptors, which were refractory to enzymatic cleavage, without altering its ability to remove receptors for HA. (Mus musculus) PubMed

 6189.

The avian C-terminal ESEV motif of influenza A virus H7N1 NS1 protein increased virulence in mice. (Mus musculus) PubMed

 6190.

The authors show that the architecture of the N-terminal domain (NTD) of Nsp1beta adopts a fold closely resembling that of several known nucleases and has intrinsic nuclease activity that is strongly activated by manganese ions.[Nsp1beta] (Mus musculus) PubMed

 6191.

This work presents a thorough analysis of the structural, functional and regulatory attributes of PfNapS from P. falciparum with respect to previously studied histone chaperones. (Mus musculus) PubMed

 6192.

Molecular and biochemical characterization of two closely related maize 9-lipoxygenase paralogs, ZmLOX4 and ZmLOX5, is reported. [ZmLOX4, ZmLOX5] (Mus musculus) PubMed

 6193.

the methyltransferase activity of RlmN and Cfr [RlmN][Cfr] (Mus musculus) PubMed

 6194.

Translesion synthesis pathways require Rad8, Mms2 and Ubc13 enzymes needed for poly-ubiquitination of proliferating cell nuclear antigen (PCNA) and for mono-ubiquitination.[Rad8, Mms2 and Ubc13] (Mus musculus) PubMed

 6195.

The objectives of this study were to dissect, quantify, and compare the effects of compatible Snn1-SnTox1 and Tsn1-SnToxA interactions on susceptibility in the wheat-S. nodorum pathosystem.[Tsn1, Snn1] (Mus musculus) PubMed

 6196.

OsZIP5 plays a role in Zn distribution within rice.[OsZIP5] (Mus musculus) PubMed

 6197.

The objectives of this study were to dissect, quantify, and compare the effects of compatible Snn1-SnTox1 and Tsn1-SnToxA interactions on susceptibility in the wheat-S. nodorum pathosystem.[Tox1, ToxA] (Mus musculus) PubMed

 6198.

Continuous-wave and pulsed electron paramagnetic resonance spectroscopy have been used to characterize two variants of bacterial sulfite dehydrogenase from Starkeya novella. [SDH] (Mus musculus) PubMed

 6199.

Now, we're going to discuss the role of plant PRA concerted with Rab and GDI proteins by recycling Rab between membrane and cytosol for intracellular trafficking of cargo proteins. [OsPRA1] (Mus musculus) PubMed

 6200.

A fine-mapping population was used to resolve the Rf2 locus to a 236,219-bp region of chromosome SBI-02.[Rf2] (Mus musculus) PubMed

 6201.

The varS gene is involved in regulation of HapA in V. cholerae strain 2740-80. Mutants exhibit decreased HapA production and increased biofilm formation. [VarS; HapA] (Mus musculus) PubMed

 6202.

The results indicate that Utp25p is a novel SSU processome subunit involved in pre-40S maturation. (Mus musculus) PubMed

 6203.

TbPAR42 is a novel Parvulin anda knockdown of TbPAR42 in its procyclic form results in reduced proliferation rates suggesting an important role in cell growth. [TbPAR42] (Mus musculus) PubMed

 6204.

The Aspergillus fumigatus medA deletion mutant exhibited reduced virulence in both an invertebrate and a mammalian model of invasive aspergillosis.[MedA] (Mus musculus) PubMed

 6205.

Comparative transcriptome analysis revealed novel roles for the Ras (ras1) and cAMP (cac1) signaling pathways in C. neoformans in both stress response and antifungal drug susceptibility.(ras1 and cac11) (Mus musculus) PubMed

 6206.

The up-regulation of miR398a/b and miR408 and the down-regulation of their respective target genes, which encode the copper proteins COX5b and plantacyanin, highlight the involvement of these miRNAs in response to water deprivation in M. truncatula. (Mus musculus) PubMed

 6207.

These results suggest that the proper distribution of nucleoids requires the YlmG protein, and the mechanism is conserved between cyanobacteria and chloroplasts.[YlmG] (Mus musculus) PubMed

 6208.

XacPNP induces changes in host photosynthesis at the level of protein expression and in photosynthetic efficiency in particular.[XacPNP] (Mus musculus) PubMed

 6209.

Murine cytomegalovirus M45-encoded inhibitor of RIP activation (vIRA) targets RIP3 during infection and disrupts RIP3-RIP1 interactions characteristic of TNFalpha-induced necroptosis, thereby suppressing both death pathways.[M45] (Mus musculus) PubMed

 6210.

These results indicate that regulation of MAFbx in salmon occurs at both the transcriptional and post-transcriptional level through production of the alternatively spliced MAFbx-beta, which is a likely target for non-sense mediated decay. (MAFbx-beta) (Mus musculus) PubMed

 6211.

Three resided in the PB1-F2 open reading frame, caused amino acid (aa) substitutions in the PB1-F2 protein, and reduced A/Vietnam/1203/H5N1 avian influenza virus lethality in mallard ducks. [Pb1-F2] (Mus musculus) PubMed

 6212.

a unique DtxR homologue (DR2539) with special characteristics from Deinococcus radiodurans was indentified. (DR2539) (Mus musculus) PubMed

 6213.

report cloning of a cDNA (Am5-ht1A) sharing high similarity with members of the 5-HT(1) receptor class; data presented mark first comprehensive study-from gene to behavior-of a 5-HT(1A) receptor in the honeybee [5-HT1A] (Mus musculus) PubMed

 6214.

The structure of glycosylated tandem repeats (TR) from Als5 was determined by ab initio modeling. Experiments showed that the hydrophobic TR domains supported binding to polystyrene and other TR domains, leading to nonsaturable homophilic binding.(Als5} (Mus musculus) PubMed

 6215.

the Orc1BAH domain was necessary for ORC's stable association with yeast chromosomes, and was physiologically relevant to DNA replication in vivo [Orc1; strain not found] (Mus musculus) PubMed

 6216.

demonstrate the direct involvement of H-NS as a positive factor stimulating translation of the malT mRNA [H-NS gene, substrain not found] (Mus musculus) PubMed

 6217.

sPLA(2)-III enhances sAPP(alpha) secretion through its action to increase membrane fluidity and recruitment of APP at the cell surface.[sPLA(2)-III] (Mus musculus) PubMed

 6218.

The regions 357-368 and 418-427 of HSP60Sp could be associated with glaucoma. [HSP60] (Mus musculus) PubMed

 6219.

The expression of surface antigen 6 (CS6) was the most prevalent colonization expressed by enterotoxigenic E. coli in children with diarrhea in Kolkata, India.[CS6] (Mus musculus) PubMed

 6220.

data indicate that the assembly of the U4-specific Sm core provides an essential step in U4/U6 di-snRNP biogenesis and splicing in trypanosomes [SSm4] (Mus musculus) PubMed

 6221.

Tsh1 encodes a GATA zinc-finger protein and is expressed in the cryptic bract primordium. Mutants fail to suppress bract development. [Tsh1] (Mus musculus) PubMed

 6222.

CSA is a key transcriptional regulator for sugar partitioning in rice during male reproductive development. (Mus musculus) PubMed

 6223.

MtSNARP1 and MtSNARP2 are members of a novel family of nodulins with RNA-binding activity. [SNARP1; SNARP2] (Mus musculus) PubMed

 6224.

under acidic conditions, HP-ferritin was upregulated at pH 5 compared to pH 7; it can switch from an iron-storage protein with ferroxidase activity to a DNA-binding/protection function upon exposure to acidic environment [HP-ferritin] (Mus musculus) PubMed

 6225.

MTS1 is involved in hyphal elongation. [MTS1] (Mus musculus) PubMed

 6226.

These results indicate that mutations in the lipid A deacylase PagL which relieve the enzyme from its latency affect the ability of PagL to interact with lipopolysaccharide.(PagL) (Mus musculus) PubMed

 6227.

The LATD/NIP gene is a member of the NRT1(PTR) transporter family, and is essential for integrating nutrient and hormone signaling with lateral root growth and nodule development. [LATD] (Mus musculus) PubMed

 6228.

UGT73F3 is a uridine diphosphate glycosyltransferase that showed specificity for multiple sapogenins in vitro and was confirmed to be involved in saponin biosynthesis in vivo. [UGT73F3] (Mus musculus) PubMed

 6229.

ARS1 and ARS2 are alkylresorcinol synthases that are likely to participate in the biosynthesis of sorgoleone. [ARS1; ARS2] (Mus musculus) PubMed

 6230.

Lsi1 plays a role in arsenite efflux in rice roots exposed to arsenate.[Lsi1] (Mus musculus) PubMed

 6231.

TehB plays a role in both resistance to oxidative damage and haem uptake and is required for infection in rat models. [tehB] (Mus musculus) PubMed

 6232.

Aah and aidA are transcribed as a bicistronic message. [aah, aidA] (Mus musculus) PubMed

 6233.

RamA and RamB are involved in the regulation of glycogen synthesis.[RamA and RamB] (Mus musculus) PubMed

 6234.

ZmMATE2 expression is not specifically localized to any particular tissue and does not respond to aluminum. [MATE2] (Mus musculus) PubMed

 6235.

PM25 is an atypical late embryogenesis-abundant protein that es not interact or stabilize phospholipid membranes in the dry state. [PM25] (Mus musculus) PubMed

 6236.

Characterized the zebrafish ortholog of nephrocystin-3 (NPHP3) by morpholino oligo-mediated knockdown. Suggest an essential role in ciliary function. (Mus musculus) PubMed

 6237.

didB Delta exacerbates the dominant-negative growth defect resulting from Vps32-GFP over-expression (Did2). (Mus musculus) PubMed

 6238.

The first 109 amino acids of DspB/F were required for binding and efficient translocation of DspA/E. [Dspa, DspB, DspF, DspE] (Mus musculus) PubMed

 6239.

preliminary characterization of A. nidulans ugeA through analysis of the ugeADelta deletion strain (UgeA). (Mus musculus) PubMed

 6240.

ZmFLS1 is a UV-B-inducible maize flavonol synthase. [FLS1] (Mus musculus) PubMed

 6241.

RIM1 functions as a regulator of the jasmonate signaling pathway and is degraded by JA treatment via a 26S proteasome-dependent pathway. [RIM1] (Mus musculus) PubMed

 6242.

SNF4b plays a role in constitutive defense responses during hydration of dormant seeds. [SNF4b] (Mus musculus) PubMed

 6243.

In an in vitro macrophage model of virulence, the sur7Delta mutant was impaired in macrophage killing.[SUR7] (Mus musculus) PubMed

 6244.

The phenotypes resulting from Pex2 deletion are no different from those of previously isolated pex mutants affected in peroxisomal protein import, and viable ascospores are produced in selfed crosses.[Pex2] (Mus musculus) PubMed

 6245.

The cDNA consisted of 1,700 nucleotides and was predicted to encode a 474-amino acid protein.[CitA] (Mus musculus) PubMed

 6246.

The results indicated that the BIR or RING motif of Antheraea pernyi nucleopolyhedrovirus inhibitor of apoptosis protein1 (IAP1) had equally function to inhibit cell apoptosis.[IAP1] (Mus musculus) PubMed

 6247.

findings show Ssp1 and Ssp2 are structurally similar to fucose-specific lectins and suggest regulatory compensation for loss of Ssp1 coupled with potential functional redundancy among lectins accumulating in sclerotia and apothecia [Ssp1, Ssp2] (Mus musculus) PubMed

 6248.

[nAChR alpha7] nAChR alpha3 and alpha7 lateral mobility is controlled by domain specific, receptor subtype dependent, and cell-type constrained mechanisms; this system could tailor nicotinic signaling capabilities to specific needs of individual locations (Mus musculus) PubMed

 6249.

We conclude increased resistance to host cathelicidin and killing within phagocyte extracellular traps contribute to the propensity of M1 GAS strains to produce invasive infections. [M1 protein] (Mus musculus) PubMed

 6250.

These findings suggest that NAD(+) glycohydrolase has a NADase-independent function and prompt a reevaluation of its role in streptococcal pathogenesis. (Mus musculus) PubMed

 6251.

Taken together, the data suggest a model for occlusion in which A26p has a bridging role between ATIp and A27p, and A27p provides a link to the mature virion membrane.[ATI, A26 & A27] (Mus musculus) PubMed

 6252.

The authors identified the putative pocket protein binding sequence (PPBS) on C42 that is essential for C42 to exert its function in nuclear actin polymerization.[C42] (Mus musculus) PubMed

 6253.

The function of quorum-sensing E. coli regulator D (QseD) in enterohemorrhagic E. coli and E. Coli K12 is reported.[QseD] (Mus musculus) PubMed

 6254.

nphT7, found in the mevalonate pathway gene cluster from a soil-isolated Streptomyces sp. strain, encodes an unusual acetoacetyl-CoA synthesizing enzyme [nphT7] (Mus musculus) PubMed

 6255.

Pom33 (YLL023C), is an evolutionarily conserved membrane protein that is functionally linked to nuclear pore complexes (NPC) components and required for proper NPC assembly and/or stability in S. cerevisiae [pom33] (Mus musculus) PubMed

 6256.

Loss-of-function mutants of PALM1 develop dissected leaves with five leaflets clustered at the tip.[PALM1] (Mus musculus) PubMed

 6257.

HP0256 is required for full motility and it is involved, possibly indirectly, in expression of outer membrane proteins and adhesins involved in pathogenesis and adhesion.[HP0256] (Mus musculus) PubMed

 6258.

crystals of MglA belonged to the hexagonal space group P6(1) or P6(5), with unit-cell parameters a = b = 125, c = 54 A.[MglA] (Mus musculus) PubMed

 6259.

crystals of HPPK belonged to space group P2(1), with unit-cell parameters a = 36.8, b = 76.6, c = 51.5 A, alpha = gamma = 90.0, beta = 100.2 degrees.[6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK)] (Mus musculus) PubMed

 6260.

crystal structures of Saccharomyces cerevisiae Poleta (also known as RAD30) in ternary complex with a cis-syn thymine-thymine (T-T) dimer and with undamaged DNA [RAD30] (Mus musculus) PubMed

 6261.

Cytomegalovirus pUL83 recruits human IFI16 to the major immediate-early promoter, and IFI16 binding at the promoter is dependent upon the presence of pUL83.[pUL83] (Mus musculus) PubMed

 6262.

Staphylococcal pathogenicity island derepression is effected by a specific, non-essential phage protein (dut) that binds to Stl, disrupting the Stl-DNA complex and thereby initiating the excision-replication-packaging cycle of the island [dut=dUTPase] (Mus musculus) PubMed

 6263.

These data show that, in addition to directly driving the transcription of the dinB gene in stationary-phase cells, RpoS regulates the activity of Pol IV in exponentially growing cells via a second, indirect pathway.[RpoS; DinB] (Mus musculus) PubMed

 6264.

Plasmodium actin-depolymerization factors 1 and 2 have been crystallized. The crystals diffracted X-rays to maximum resolutions of 2.0 and 2.1 A.[actin-depolymerization factor 1 and actin-depolymerization factor 2] (Mus musculus) PubMed

 6265.

Plasmodium actin-depolymerization factors 1 and 2 have been crystallized. The crystals diffracted X-rays to maximum resolutions of 2.0 and 2.1 A.[actin-depolymerization factor 1 and actin-depolymerization factor 2] (Mus musculus) PubMed

 6266.

Native and SeMet-derivative crystals of D/C mosaic neurotoxin showed X-ray diffraction to 2.8 and 3.1 A resolution, respectively. [botulinum toxin type C and botulinum toxin type D] (Mus musculus) PubMed

 6267.

Staphylococcal pathogenicity island derepression is effected by a specific, non-essential phage protein (dut) that binds to Stl, disrupting the Stl-DNA complex and thereby initiating the excision-replication-packaging cycle of the island [dut=dUTPase] (Mus musculus) PubMed

 6268.

SeDsbA, SeDsbL and SeSrgA crystals diffracted to resolution limits of 1.55, 1.57 and 2.6 A and belonged to space groups P2(1), P2(1)2(1)2 and C2, respectively.[DsbL] (Mus musculus) PubMed

 6269.

Our results showed that functional deficiency due to frameshift mutation and subsequent nonsense mutation in perA reduced BFP expression in typical EPEC strains isolated in Japan.[perA, BfpA] (Mus musculus) PubMed

 6270.

Structures of Nup145N residues 443-605 [Nup145N(443-605)] from the larger autoproteolytic segment, are described.[Nup145] (Mus musculus) PubMed

 6271.

The authors demonstrate that that two DNA replication proteins are substrates of Pfmrk-mediated phosphorylation and that PfMAT1 confers substrate specificity to the Pfmrk kinase complex.[Pfmrk & PfMAT1] (Mus musculus) PubMed

 6272.

study shows highly dynamic regulation of Crmp-2 forms during development and identifies post-translational changes in Crmp-2 as putative contributors to the maintenance of spinal-cord regenerative ability [Crmp-2] (Mus musculus) PubMed

 6273.

Rice with Xa7 exhibited less disease than lines without Xa7 over 11 yr, even though virulence of Xoo field populations increased. Xa7 restricted disease more effectively at high than at low temperatures. [Xa7] (Mus musculus) PubMed

 6274.

The effects of secG and secY2 mutations in the extracellular proteome biogenesis of S. aureus are reported; the effects of mutations on organism virulence are included.[secG; sexY2] (Mus musculus) PubMed

 6275.

These results indicate that NADase is important for the virulence of Streptococcus pyogenes in vivo and is the potential target to suppress the virulence.[NADase] (Mus musculus) PubMed

 6276.

The interactions of Poly(A) polymerase I (PAP I) with multiple rpoteins in the RNA degradosome, and the role of RssB in its maintenance are reporte.[RssB; PAP I] (Mus musculus) PubMed

 6277.

study demonstrated significant in vitro activities and multifaceted specificities of protein arginine methyltransferases (PRMTs) and provided evidence for a role of protein methylation in mechanisms of oxidative stress response [RmtA,RmtB,RmtC] (Mus musculus) PubMed

 6278.

It was also shown that the CH domains are functional and bind to F-actin, whereas the BAR and GBD/FH3 domains interact in vitro and in vivo with different families of GTPases such as Rho and Ras, and with different phosphoinositides.[EhNCABP166] (Mus musculus) PubMed

 6279.

The structure of GlgX from Escherichia Coli K12 was determined at 2.25 A resolution.[GlgX] (Mus musculus) PubMed

 6280.

Lis1, nuclear migration protein, controls microtubule dynamics and thus the regulated delivery of vesicles to growth sites and other cell domains that govern nuclear movements.[Lis1] (Mus musculus) PubMed

 6281.

roles of both cytoplasmic N and C termini in channel assembly and stability of KcsA were determined.[KcsA] (Mus musculus) PubMed

 6282.

both JBP2 and JBP1 are capable of stimulating de novo base J-synthesis (JBP1 and JBP2). (Mus musculus) PubMed

 6283.

Alpha-phosphoglucomutase isozymes were characterized and the data indicated that TgPGM-I, but not TgPGM-II, may play an important role in alpha-D-glucose 6-phosphate production. [PGM-I, PGM-II] (Mus musculus) PubMed

 6284.

The authors demonstrate that VrrA RNA represses ompT translation by base-pairing with the 5' region of the mRNA and that regulation requires the RNA chaperone protein Hfq.[VrrA, OmpT, Hfq] (Mus musculus) PubMed

 6285.

This study reports a high-resolution NMR structure for full-length myristoylated yeast (Saccharomyces cerevisiae) Arf1 in complex with a membrane mimic. [Arf1] (Mus musculus) PubMed

 6286.

This study shows formation of large inverted chromosome duplications at the site of a 246 bp interrupted DNA palindrome in the absence of the SbcCD and the RecA.[SbcC, SbcD, RecA] (Mus musculus) PubMed

 6287.

CvfB represents a novel assembly of modules for binding RNA [CvfB] (Mus musculus) PubMed

 6288.

structural insights into sialyl transfer by the trans-sialidase (Mus musculus) PubMed

 6289.

AbsB and AdpA participate in a post-transcriptional regulatory loop that modulates the cellular levels of the proteins encoded by both genes (AbsB and AdpA). (Mus musculus) PubMed

 6290.

The N-terminal 107 residues of ColA (TA1-107) bound to TolB to show that the TolB box of ColA consists of a 12-residue domain that binds to the beta-propeller canyon of TolB (ColA). (Mus musculus) PubMed

 6291.

These studies suggest that besides the conserved helicase domain of the novel DEAD box helicase Has1p,the highly variable N-terminal region also contributes in the activity of the protein. [Has1p] (Mus musculus) PubMed

 6292.

Mutagenesis studies support that the proline-induced structural twist contributes directly to gyrase's (-) supercoiling activity (gyrase A subunit). (Mus musculus) PubMed

 6293.

Streptolysin O mutants that are unable to form pores retain the ability to translocate nicotinamide adenine dinucleotide-glycohydrolase.[Streptolysin O] (Mus musculus) PubMed

 6294.

A model for EhC2A-mediated regulation of the transcriptional activities of URE3-BP via Ca(2+)-dependent anchoring of the transcription factor to the amebic plasma membrane, is proposed.[URE3-BP, EhC2A] (Mus musculus) PubMed

 6295.

sporozoite latency is an active process controlled by a eukaryotic initiation factor-2alpha (eIF2alpha) kinase (IK2) and a phosphatase.[IK2] (Mus musculus) PubMed

 6296.

Septum-associated microtubule-organizing centers share at least two further components, gamma-tubulin and GcpC (S. pombe Alp6) with spindle pole bodies and ApsB interacts with gamma-tubulin.[ApsB, gamma tubulin] (Mus musculus) PubMed

 6297.

These results show that enteropathogenic Escherichia coli effector NleH acts via a global anti-apoptotic pathway.[NleH] (Mus musculus) PubMed

 6298.

Study demonstrates that SCO5725 (EsxA) and SCO5724 (EsxB) in S. coelicolor are novel morphogenetic proteins whose secretion is dependent on functions encoded by at least two other genes in the locus.[EsxA, EsxB] (Mus musculus) PubMed

 6299.

Based on its cell-division-dependent localization and interaction with FtsZ, study proposes that StkP plays a currently undefined role in cell division of pneumococcus.[StkP] (Mus musculus) PubMed

 6300.

The authors provide evidence that the aryl alcohol dehydrogenase NorA (AflE) encoded by the aflatoxin biosynthetic gene cluster in Aspergillus flavus affects the accumulation of aflatoxins in the final steps of aflatoxin biosynthesis.[NorA] (Mus musculus) PubMed

 6301.

Using in vivo and in vitro binding assays, study showed that this motif anchors the SciZ protein to the cell wall and is required for Type VI secretion systems function.[SciZ] (Mus musculus) PubMed

 6302.

OmpC is compared to its structural homolog OmpF at different KCl concentrations, pH values, and a broad temperature range. [OmpC][OmpF] (Mus musculus) PubMed

 6303.

insight into the molecular basis for the distinct functional properties of OmpU and OmpT proteins [OmpU][OmpT] (Mus musculus) PubMed

 6304.

The membrane topology of a recently recognized Gtr, GtrIc, which is known to mediate S. flenxeri serotype switching from 1a to 1c, is presented.[GtrIc] (Mus musculus) PubMed

 6305.

Sclerotinia sclerotiorum agglutinin reveals a novel dimeric assembly markedly dissimilar to those described earlier for ricin-type lectins.[Sclerotinia sclerotiorum agglutinin] (Mus musculus) PubMed

 6306.

P-TEFb is recruited to the promoter in a catalytically inactive state bound to the inhibitory 7SK small nuclear ribonucleoprotein (snRNP), thereby preventing elongation.[small nuclear ribonucleoprotein] (Mus musculus) PubMed

 6307.

the role of Tlp1 as a chemoreceptor was investigated using isogenic mutants and through analysis of protein-protein interactions with the predicted chemotaxis proteins of C. jejuni NCTC 11168 using the yeast hybrid systems (Tlp1). (Mus musculus) PubMed

 6308.

TbPLK has accomplished its role in guiding cytokinesis before the late S phase, presumably by phosphorylating a certain substrate(s) during S phase, which may play a critical role in initiating the subsequent cytokinesis.[TbPLK] (Mus musculus) PubMed

 6309.

This work shows that the sigma(R)-RsrA system plays a more significant role in protein quality control than previously realized, and emphasizes the importance of controlling the cellular thiol-disulphide redox balance.[sigR] (Mus musculus) PubMed

 6310.

This is the first molecular dynamic study that simulates the whole tetrameric catalase structure immersed in water and in a H2O2 solution. [catalase-1] (Mus musculus) PubMed

 6311.

The authors show that in Schizosaccharomyces pombe, mating-specific cell adhesion is dependent on the exocyst subunit Sec8p, but independent of the exocyst subunit Exo70p.[Sec8p & Exo70p] (Mus musculus) PubMed

 6312.

In this study, three Panton-Valentine Leukocidin gene carrying methicillin-susceptible Staphylococcus aureus (MSSA) strains (M1-AAG42B, PY30C-b and YF1B-b) were isolated from different food samples in Kesan-Edirne, Turkey. (Mus musculus) PubMed

 6313.

the critical role of RAD51 in controlling the balance between targeted and random integration events observed upon transgenesis [RAD51] (Mus musculus) PubMed

 6314.

A focal gradient of MAG can induce polarized endocytosis with asymmetric redistribution of beta1-integrin and vinculin-containing contact adhesions in axonal growth cones (MAG, myelin-associated glycoprotein) (Mus musculus) PubMed

 6315.

The authors found a strong correlation between the macroscopic translocation rates and the binding affinity of the translocating NS3h protein for the respective substrates such that weaker affinity corresponded to faster translocation.[NS3] (Mus musculus) PubMed

 6316.

Nitroreductase NRSal from Salmonella typhimurium is a versatile biocatalyst that displays both nitroreductase and enoate reductase activity.[nitroreductase] (Mus musculus) PubMed

 6317.

The TaNIP gene codes for an aquaporin that markedly improved salt tolerance of transgenic Arabidopsis plants. [NIP] (Mus musculus) PubMed

 6318.

structure of urate oxidase was refined at atomic resolution (1 A) using new crystal data in the presence of xanthine and at near-atomic resolution (1.3-1.7 A) in complexes with the natural substrate (urate) [ urate oxidase ] (Mus musculus) PubMed

 6319.

The data presented constitutes a targeted analysis of the formation of the GtrV active site and highlights the essential role of the large periplasmic Loop 2 in its function.[GtrV] (Mus musculus) PubMed

 6320.

These data provide a causal link between changes in the J protein partner and specialization of duplicate Hsp70.[Jac1, Hsp70] (Mus musculus) PubMed

 6321.

S. cerevisiae thr1Delta and thr4Delta mutants were severely depleted after only 4 h in vivo. Similarly, Candida albicans thr1Delta mutants, but not hom3Delta mutants, were significantly attenuated in virulence.[Homoserine kinase] (Mus musculus) PubMed

 6322.

Results strongly indicate that the main function of HmuP is the transcriptional regulation of shmR.[HmuP] (Mus musculus) PubMed

 6323.

Neurospora cry encodes a DASH-type cryptochrome that appears capable of binding flavin adenine dinucleotide (FAD) and methenyltetrahydrofolate (MTHF). [Cryptochrome] (Mus musculus) PubMed

 6324.

Delayed re-endothelialization with rapamycin-coated stents is rescued by the addition of a glycogen synthase kinase-3beta inhibitor. (Mus musculus) PubMed

 6325.

a different, but also effective, electron-transfer cascade is conserved among the class II photolyases [class II cyclobutane pyrimidine dimer photolyases] (Mus musculus) PubMed

 6326.

TgSPATR (secreted protein with an altered thrombospondin repeat) of Toxoplasma gondii (TgSPATR), is probably new member of microneme protein and maybe involved in parasite invasion. [TgSPATR] (Mus musculus) PubMed

 6327.

The study reports the first crystal structure of a DEAH/RHA helicase: the full-length yeast Prp43 in complex with ADP/Mg2+ at 1.9 A resolution.[Prp43] (Mus musculus) PubMed

 6328.

analysis of the humoral immune response against the prokaryotic expressed N-terminal autoprotease (N(pro)) protein of bovine viral diarrhoea virus [N(pro)] (Mus musculus) PubMed

 6329.

NOPP44/46 is a major substrate of TbPTP1.[TbPTP1, NOPP44/46] (Mus musculus) PubMed

 6330.

HBV/P22 protein could inhibit the induced apoptosis of HepG2 cells both in vitro and in vivo. [p22] (Mus musculus) PubMed

 6331.

Strains expressing EibG-alpha and EibG-beta displayed a mostly typical chain-like adherence pattern (CLAP), with formation of long chains on both human and bovine intestinal epithelial cells. (Mus musculus) PubMed

 6332.

Expression of the NS1 proteins resulted in inhibition of host innate immune responses (beta interferon and protein kinase R production).[NS1] (Mus musculus) PubMed

 6333.

The authors demonstrated that the LuxS/AI-2 signaling system regulates capsular polysaccharide production via a two-component system, KdpDE, whose function has not yet been clarified in Staphylococcus aureus.[KdpE] (Mus musculus) PubMed

 6334.

An R217A substitution in the J domain-interacting surface of BiP compromised the physical and functional interaction with Sec63p, an Hsp40 required for Eendoplasmic reticulum translocation.[BiP] (Mus musculus) PubMed

 6335.

These results not only provide evidence that mRNA unwinding by eIF4A stimulates start codon recognition, but also suggest that the eIF4A-binding site on eIF4G made of the HEAT domain stimulates the ribosomal scanning independent of eIF4A.[eIF4A, eIF4G] (Mus musculus) PubMed

 6336.

Imidazole binding to cyt c(1) substantially lowers the midpoint potential of the heme and fully inhibits bc(1) complex activity.[Cytochrome c1] (Mus musculus) PubMed

 6337.

The kinetics of imidazole (Im) and N-methylimidazole (MeIm) binding to oxidized cytochrome (cyt) c(1) of detergent-solubilized bc(1) complex from Rhodobacter sphaeroides are described.[Cytochrome c1] (Mus musculus) PubMed

 6338.

TGF-beta1 modulates the expression of IGFBP-4 and PAPP-A in cultured periosteal explants.[PAPP-A, rabbit; and IGFBP-4, rabbit] (Mus musculus) PubMed

 6339.

The results suggest evolutionary adaptation of ASIC1 to match the value of the species-specific plasma pH.[ASIC1] (Mus musculus) PubMed

 6340.

These results suggest that EDIN is a risk factor for Staphylococcus aureus dissemination through the vasculature by virtue of its ability to promote the formation of infection foci in deep-seated tissues.[EDIN] (Mus musculus) PubMed

 6341.

Rab5 and Rab7, were associated with the pathway of autophagosome formation and the fate of intracellular group A streptococcus. (Mus musculus) PubMed

 6342.

These data place Isd11 at the center of these sulfur transactions and raises the possibility of a connection between Fe/S metabolism and protein synthesis, helping integrate two seemingly unrelated pathways.[Isd11] (Mus musculus) PubMed

 6343.

results demonstrate the involvement of Pbr on the regulation of phenazine biosynthesis, and an important role for this regulatory protein on several cellular processes related to stress resistance and virulence[Pbr] (Mus musculus) PubMed

 6344.

T. gondii PBGS displays a broad activity peak (pH 7-8.5), with a K(m) for aminolevulinic acid of approximately 150 microM and specific activity of approximately 24 micromol of porphobilinogen/mg of protein/h.[PBGS] (Mus musculus) PubMed

 6345.

These results show that the H274Y NA mutation affects the fitness of two H5N1 influenza viruses differently. (Mus musculus) PubMed

 6346.

The authors report that CD2AP, an endocytosis-associated and cortactin-binding protein, is a novel and important component of enteropathogenic Escherichia coli pedestal formation that also utilizes Y474 phosphorylation of the bacterial Tir.[Tir] (Mus musculus) PubMed

 6347.

Seven mutants showed notable abnormalities in processing (constructs with the E1231A, E1249A, and R1374A mutations) and beta-barrel assembly or insertion into the outer membrane (constructs with the G1158Y, F1360A, Y1375A, and F1377A mutations).[EspP] (Mus musculus) PubMed

 6348.

By introducing the M112/M113 mutations into wt murine cytomegalovirus, the authors demonstrated that they are sufficient to facilitate murine cytomegalovirus replication in human cells.[M113] (Mus musculus) PubMed

 6349.

These results suggest that Epidermal Growth Factor (EGF)-like Cyst Protein 1(EGFCP1)s may function like cyst wall proteins, involved in differentiation of Giardia lamblia trophozoites into cysts.[EGFCP1] (Mus musculus) PubMed

 6350.

These data suggest that HpHSP60 enhances angiogenesis via CXCR2/PLCbeta2/Ca2+ signal transduction in endothelial cells.(HSP60) (Mus musculus) PubMed

 6351.

Data suggest that there are three factors that govern nucleoprotein oligomerization: interaction between the tail loop and the insertion groove, maintenance of the tail loop conformation, and stabilization of the NP homo-oligomer [H1N1 NP] (Mus musculus) PubMed

 6352.

Data show that OrfA acts to markedly reduce cell surface expression of the FIV primary binding receptor, CD134. (Mus musculus) PubMed

 6353.

The authors present evidence that CadC negatively regulates the expression of the arginine-dependent adaptive acid-resistance system (AR3), encoded by the adi locus while it has no effect on the expression of AR1 and AR2 systems.[CadC] (Mus musculus) PubMed

 6354.

results suggest a role for SkzL in S. agalactiae pathogenesis through fibrinolytic enhancement [Skzl] (Mus musculus) PubMed

 6355.

analysis of interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46 [IFT46] (Mus musculus) PubMed

 6356.

These findings strongly implicate steric hindrance as the mechanism of repression of rob by MarA.[marA; rob] (Mus musculus) PubMed

 6357.

These results explain the inhomogeneous distribution of OmpR in and demonstrate that binding to native sites in the chromosome can be imaged and quantified by fluorescence microscopy.[OmpR] (Mus musculus) PubMed

 6358.

The effects of site-directed mutagenesis on the export and metabolism of cytolysin A, a cytolytic pore-forming toxin, are reported.[ClyA] (Mus musculus) PubMed

 6359.

Cln3 is involved in the mechanism underlying sporulation incompetence by inhibiting IME1 transcription and the Ime1-Ume6 interaction [strain Kyokai no 7 (K7); genes: Cln3, IME1, Ume6] (Mus musculus) PubMed

 6360.

This study show that when E. coli's origin of replication is substituted by V. Cholerae oriCI, dam, but not seqA, becomes important for growth, arguing that Dam methylation exerts a critical function at the origin of replication.[dam] (Mus musculus) PubMed

 6361.

PTP1 protein induces cd8+ T cell immunity (Mus musculus) PubMed

 6362.

Promoter of penicillin biosynthesis genes pcbC gene didn't contain TATA box-like sequence but pcbAB and penDE contain proposed TATA boxes. [pcbC, pcbAB and penDE] (Mus musculus) PubMed

 6363.

identify the catalytic and coenzyme binding domains of L-arabinitol 4-dehydrogenase (LAD1) from Hypocrea jecorina [LAD1]. (Mus musculus) PubMed

 6364.

Findings provide evidence that gamma-glutamyl transpeptidase (GGT) is a pathogenic factor associated with H pylori-induced peptic ulcer disease. (Mus musculus) PubMed

 6365.

These data suggest that RssAB signaling negatively regulates prodigiosin production, and such inhibition is mediated through direct and specific repression of transcriptional activity of the pig operon.[RssA, RssB, PigA] (Mus musculus) PubMed

 6366.

The data show that Plasmodium falciparum PFE0485w can functionally complement a Saccharomyces cerevisiae temperature-sensitive pik1 mutation.[pik1] (Mus musculus) PubMed

 6367.

Mouse antiserum raised against recombinant KPA3 recognized a 21.8kDa protein, which was found, by indirect immunofluorescence and immunoelectron microscopy, to be associated with the Trypanosoma cruzi kinetoplast.[KAP3] (Mus musculus) PubMed

 6368.

Host membrane phosphatidylserine plays a key role in the delivery, localization, and pathophysiological action of CagA. (Mus musculus) PubMed

 6369.

This study used bioinformatic and statistical analyses to evaluate whether the allelic diversity of the outer membrane proteins homB and homA is generated by recombination.[homA; homB] (Mus musculus) PubMed

 6370.

The analysis of chromosomal segregation in smc (structural maintenance of chromosomes) and spoIIIE single and double mutants unravels differences in the chromosome dynamics in the spherical staphylococcal cells compared to the model in rods.[SMC; SpoIIIE] (Mus musculus) PubMed

 6371.

crystal structure of KcsA in its open-inactivated conformation and investigation of the mechanism of C-type inactivation gating at the selectivity filter from channels 'trapped' in a series of partially open conformations [KcsA] (Mus musculus) PubMed

 6372.

side-chain rearrangements at position 103 mechanically couple activation and inactivation in KcsA [KcsA] (Mus musculus) PubMed

 6373.

Simulations of diffusion and exchange of GFP-Ras2 between the membrane and cytosol show that the spatial dependence of fluorescence recovery after photobleaching curves can be used to account for exchange if it occurs.[Ras2] (Mus musculus) PubMed

 6374.

Cdc13 can bind to the telomeric template for lagging-strand replication.[Cdc13] (Mus musculus) PubMed

 6375.

Ecm29 functions as scaffold protein during the remodeling of incompletely matured RP-CP assemblies into regular enzymes. [Ecm29] (Mus musculus) PubMed

 6376.

Expansion of the target of rapamycin (TOR) kinase family and function shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity. (TOR3) (Mus musculus) PubMed

 6377.

Data highlight a potential human adaptation of NS1 that seems absent in "classically derived" swine-origin influenza A viruses, including the 2009 H1N1 virus[NS1] (Mus musculus) PubMed

 6378.

TCRR-1 and TCRR-2 encode type-A response regulators whose expression is cell type specific and developmentally regulated. (Mus musculus) PubMed

 6379.

Oryza sativa Rac1 is activated by Pit during pathogen attack and plays a critical role in Pit-mediated immunity in rice.[Rac1 & Pit] (Mus musculus) PubMed

 6380.

This study indicates a possible role for AdhC in aldehyde metabolism and a broader role for NmlR(sp) in the regulation of carbon metabolism.[NmlR(sp)] (Mus musculus) PubMed

 6381.

The roles of the pca gene in carbon dioxide metabolism and growth of S. pneumoniae under carbon dioxide-poor conditions are reported.[pca] (Mus musculus) PubMed

 6382.

Data show that human Daxx-mediated repression of LUNA during lytic infection absolutely requires IE72 gene expression[IE72] (Mus musculus) PubMed

 6383.

The putative virulence factor C protein beta was found to be upregulated under the conditions hypothesised to reflect those associated with foetal exposure to Streptococcus agalactiae.[C protein beta] (Mus musculus) PubMed

 6384.

Targeted disruption of the pkrp gene in Plasmodium berghei, a rodent model of malaria, compromises the ability of parasites to infect different tissues within the mosquito host.[pkrp] (Mus musculus) PubMed

 6385.

Data suggest that PKA signalling is required for cercarial viability and may play a specific role in the reproductive activity of adult Schistosoma mansoni worms.[protein kinase A] (Mus musculus) PubMed

 6386.

These observations suggest that glutamine synthase is essential to NH(4)(+) repression of nitrogenase and that deletion of glnA1 results in the complete derepression of nitrogenase by preventing NH(4)(+) assimilation in vivo.[glnA1] (Mus musculus) PubMed

 6387.

the role of the unscheduled meiotic gene expression 6 (UME6) gene in Kluyveromyces lactis (Mus musculus) PubMed

 6388.

genetic and biochemical evidence that the Lon protease and the SecB and DnaJ/Hsp40 chaperones are involved in the quality control of presecretory proteins in Escherichia coli. [Lon protease][SecB][DnaJ] (Mus musculus) PubMed

 6389.

ArcAB two-component system of S. enterica stimulates pSLT transfer under microaerobiosis by two concerted actions: activation of the tra operon and repression of the sdhCDAB operon.[ArcA][ArcB][SdhA][SdhB][SdhC][SdhD] (Mus musculus) PubMed

 6390.

Accumulation of sorghum 3-deoxyanthocyanidin phytoalexins and resistance to C. sublineolum in sorghum require a functional y1 gene. (Mus musculus) PubMed

 6391.

Cop6, a sesquiterpene synthase, is a "high-fidelity" alpha-cuprenene synthase that retains its fidelity under various conditions tested.[Cop4, Cop6] (Mus musculus) PubMed

 6392.

CagL may contribute directly to H. pylori pathogenesis by promoting aberrant signaling cross-talk within host cells. (Mus musculus) PubMed

 6393.

UmuD(2), when bound to DinB, displaces the equilibrium in favor of the non-slipped conformation, thereby preventing frameshifting and potentially enhancing DinB activity on non-slipped substrates[DinB & UmuD] (Mus musculus) PubMed

 6394.

our data reveal the existence of a cross-talk between the canonical Wnt pathway and the Sir2-FoxO longevity pathway to protect against mutant PABPN1 toxicity [PABPN1] (Mus musculus) PubMed

 6395.

identified 32 transgene-positive zebrafish, transmitting one or more independent constructs displaying ASCL1-like regulatory control. [ASCL1] (Mus musculus) PubMed

 6396.

solid-state NMR chemical shift fingerprints of two distinct conformations of the selectivity filter; changes are observed in the chemical shifts of key residues in the filter as the potassium ion concentration is changed from 50 mM to 1 muM (KcsA channel) (Mus musculus) PubMed

 6397.

Data show that the florigen gene Hd3a (Heading date 3a) is toggled by only a 30-min day-length reduction: [Hd3a] (Mus musculus) PubMed

 6398.

Using U373MG cells we found that IE86 protein was bound to cellular Mcm3, but did not inhibit the cellular DNA synthesis. (IE86) (Mus musculus) PubMed

 6399.

identification of the protease responsible for proteolytic cleavage ta C-terminus of SAGA complex and generation of SLIK protein complex [Pep4p] (Mus musculus) PubMed

 6400.

ACO1 has a little effect on internode elongation at the heading stage. [ACO1] (Mus musculus) PubMed

 6401.

it appears that cryptochrome 1 has significant spectroscopic and electrochemical similarities to Escherichia coli DNA photolyase. (Mus musculus) PubMed

 6402.

The structures of the apoenzyme and the reaction intermediate (pantoyl adenylate; PA) complex were determined by X-ray crystallographY [pantothenate synthetase] (Mus musculus) PubMed

 6403.

information on the ability of RNase BN to process tRNA precursors [RNase BN] (Mus musculus) PubMed

 6404.

Dmr1p is therefore the first yeast pentatricopeptide repeat protein, which has an rRNA target and is probably involved in the biogenesis of mitochondrial ribosomes and translation.[DMR1] (Mus musculus) PubMed

 6405.

The expression of II type collagen and MMP-7 is correlated to a retrogression of acetabular cartilage and increases obviously in early developmental dysplasia. (Mus musculus) PubMed

 6406.

These results indicated that Plasmodium ADF2 plays a pivotal role in transformation in the malaria parasite life cycle.[ADP2] (Mus musculus) PubMed

 6407.

report the identification of Dbx1 as a direct target of Gsh2-mediated transcriptional repression, and show that a series of cross-repressive interactions[Gsh2] (Mus musculus) PubMed

 6408.

OsRZ2 complements the defect in mRNA export from the nucleus to the cytoplasm in grp7 mutant plants during cold stress. [RZ2] (Mus musculus) PubMed

 6409.

These results raise the possibility that the activity of AphB is influenced by the pH and oxygen tension of the environment.[AphB] (Mus musculus) PubMed

 6410.

the high-resolution crystal structures of substrate-loaded Asp105Asn and His88Gln mutants of Synechocystis sp. PCC 6803 PcyA in the initial oxidized and one-electron reduced radical states were reported.(PcyA) (Mus musculus) PubMed

 6411.

The identification and functional characterisation of the eroA and ervA genes from Aspergillus niger, is described.[eroA, ervA] (Mus musculus) PubMed

 6412.

The combined results suggest a unique mechanism that ensures the transport of a single substrate by the SecA2/Y2 system.[SecA2 & SecY2] (Mus musculus) PubMed

 6413.

Results of the present study indicate that the FecL(L) mutation could act on the ovaries by modulating follicular development and by modulating, indirectly or directly. (FecL(L)) endocrine profiles [FecL] (Mus musculus) PubMed

 6414.

AggR regulates its own expression in mammalian intestind during EAEC infection. [AggR] (Mus musculus) PubMed

 6415.

a putative role in autoregulation of nodulation; linked to proliferation and differentiation [CLE12, CLE13] (Mus musculus) PubMed

 6416.

Studies show that the 1.9-A resolution crystal structure of the basal pilin FctB, revealing an immunoglobulin (Ig)-like N-terminal domain with an extended proline-rich tail: [ pilin FctB] (Mus musculus) PubMed

 6417.

Our data suggest that a neuromeddin U receptor (nmur-1) processes information from specific food cues to influence lifespan and other aspects of physiology. (Mus musculus) PubMed

 6418.

MADD-2 is a UNC-40 cofactor in axon attraction and branching, paralleling the role of UNC-5 in repulsion;, targeting of a guidance factor to specific axonal branches can confer differential responsiveness to guidance cues.(MADD-2 PROTEIN, C ELEGANS) (Mus musculus) PubMed

 6419.

Our results suggest that MADD-2 may enhance UNC-40 pathway activity by facilitating an interaction between UNC-40 and UNC-73(MADD-2 PROTEIN, C ELEGANS) (Mus musculus) PubMed

 6420.

RecQ helicase might act on the DNA structures that are generated by the processing of DNA by the MutSLH complex and UvrD helicase.[RecQ, RecJ, MutS, UvrD] (Mus musculus) PubMed

 6421.

We have identified the transcription factor Tec1 as the last component of the newly evolved signal transduction pathway that regulates the pheromone response of the white cell phenotype in Candida albicans. [Tec1] (Mus musculus) PubMed

 6422.

the differences among the P. vivax circumsporozoite protein variants are restrict to the central repeated region of the protein, mostly nucleotide variation with important serological consequences [circumsporozoite protein, p vivax] (Mus musculus) PubMed

 6423.

Findings suggest that p13 may have a distinct impact on T cell turnover depending on the inherent ROS level: [p13] (Mus musculus) PubMed

 6424.

Expression of MYBS3 is ubiquitous and is activated by cold stress. It suppresses the DREB1-dependent pathway under prolonged cold stress. [MYBS3; DREB1] (Mus musculus) PubMed

 6425.

ETA gene was transferred by three phages into non-toxigenic S. aureus strains responsible for outbreaks of pemphigus neonatorum in the Czech Republic. [ETA] (Mus musculus) PubMed

 6426.

Study determined the crystal structure of Galactitol 2-dehydrogenase (GatDH) in complex with its cofactor NAD(H) and three different substrates from Rhodobacter sphaeroides strain D: [GatDH] (Mus musculus) PubMed

 6427.

Differential expression of CYP51, 14-SR as well as C4MO would contribute to the MAS synthesis and metabolism in response to gonadotropins in the rabbit ovary and testis.[CYP51][14-SR][C4MO] (Mus musculus) PubMed

 6428.

observe synthetic-negative interactions between mutations in the switch loop of RF1 and in helix 69 of 23S rRNA, revealing that these structural features interact functionally in the termination process.[release factor 1] (Mus musculus) PubMed

 6429.

CymR plays a major role in virulence and adaptation of S. aureus for survival within the host (Mus musculus) PubMed

 6430.

The thylakoid phosphoproteome of the wild-type strain and the stt7 mutant of Chlamydomonas under state 1 and state 2 conditions, was investigated.[Stt7] (Mus musculus) PubMed

 6431.

Potential chicken specific miR-143 target sites were also validated for LPIN1, PCK2, PYCR2, METTL14, SLC2A2 and TNFSF10. (Mus musculus) PubMed

 6432.

STAR-2 binds tightest to a consensus hexamer that more closely resembles the sequence preferred by Qk-1 rather than GLD-1 (STAR-2). (Mus musculus) PubMed

 6433.

Results indicate that PsiA is also involved in prestalk cell differentiation in Dictyostelium discoideum strain Ax2: [PsiA] (Mus musculus) PubMed

 6434.

MEAT1 shows no appreciable conformational change upon UTP binding and apparently does not require RNA substrate to select a cognate nucleoside triphosphate.[MEAT1] (Mus musculus) PubMed

 6435.

Data show that structural study combined with functional analyses provides essential information for understanding the reaction mechanism of bacterial UGPases, as well as a platform for the development of novel antibacterial agents: [HpUGPase] (Mus musculus) PubMed

 6436.

Noncollagenous region of the streptococcal collagen-like protein is a trimerization domain that supports refolding of adjacent homologous and heterologous collagenous domains. (Mus musculus) PubMed

 6437.

Dil 1 protein is required to prevent meiosis I homolog non-disjunction. (Mus musculus) PubMed

 6438.

Large and irregular oil clusters were observed in cells of double mutant seeds. [OLE16 and OLE18] (Mus musculus) PubMed

 6439.

demonstrate that the expression of a Medicago truncatula gene named Vapyrin is essential for arbuscule formation, and also for efficient epidermal penetration by Arbuscular mycorrhizal fungi. [Vapyrin] (Mus musculus) PubMed

 6440.

crystals of nucleoside diphosphate kinase 1 belonged to the trigonal space group P3, with unit-cell parameters a = b = 127.84, c = 275.49 A.[nucleoside diphosphate kinase 1] (Mus musculus) PubMed

 6441.

P1 proteins play a key role in maintaining a subtle equilibrium between defense and counter-defense mechanisms, to insure efficient virus multiplication and the preservation of host integrity.[ P1 protein ] (Mus musculus) PubMed

 6442.

Pkd1a/b and pkd2 interact to regulate extracellular matrix secretion or assembly, and that altered matrix integrity may be a primary defect underlying autosomal dominant polycystic kidney disease tissue pathologies.[pdk1] (Mus musculus) PubMed

 6443.

In this study, they characterize the choC gene encoding a putative highly conserved phospholipid methyltransferase. (Mus musculus) PubMed

 6444.

results revealed that seven of the animals (70%) were homozygous for the same combination of microsatellite alleles of myostatin observed in the Texel[Myostatin ] (Mus musculus) PubMed

 6445.

The crown of the HIV-1 envelope glycoprotein gp120 V3 has four conserved structural elements.[gp120] (Mus musculus) PubMed

 6446.

These data suggest that TaCAD1 is the predominant CAD in wheat stem for lignin biosynthesis and is critical for lodging resistance.[CAD1] (Mus musculus) PubMed

 6447.

By inhibiting E-cadherin expression and enhancing ICAM-1 expression, LMP1 may reduce the cell-cell adhesive ability and improve the cell-matrix adhesive ability and migratory ability of nasopharyngeal carcinoma cells. [LMP-1] (Mus musculus) PubMed

 6448.

The results demonstrate that MPR1/azetidine-2-carboxylic acid is a safe and efficient selection system that does not involve microbial antibiotic or herbicide resistance genes.[MPR1] (Mus musculus) PubMed

 6449.

Expression and characterization of PKL01, an Ndr kinase homolog in Lotus japonicus. (Mus musculus) PubMed

 6450.

Subcellular localization, expression patterns and patterns sugar transport ability of OsTMT1 and OsTMT2 were analysed.[OsTMT1, OsTMT2] (Mus musculus) PubMed

 6451.

LMP1 is expressed in lymph node metastatases in nasopharyngeal carcinoma. Expression is positively correlated with Fascin, pStat3 and the proliferation index of tumor cells. [LMP-1] (Mus musculus) PubMed

 6452.

report on the binding of HIV-1 gp120 to the cytoplasmic C-terminus of the voltage-gated potassium channel BEC1, an interaction that can result in the repression of BEC's activity and the inhibition of HIV-1 particle-release (gp120) (Mus musculus) PubMed

 6453.

Dauer pheromone and gpa-3 signaling modulate the coordination of intraflagellar transport of kinesin-II and OSM-3. [kinesin-II] (Mus musculus) PubMed

 6454.

ZFP179 plays a crucial role in the plant response to salt stress, and is useful in developing transgenic crops with enhanced tolerance to salt stress.[ZFP179] (Mus musculus) PubMed

 6455.

BmTh gene is responsible for the sch mutation, which plays an important role in melanin synthesis producing neonatal larval color.[Sch] (Mus musculus) PubMed

 6456.

Active transport of mannitol only takes place when EII(mtl) becomes phosphorylated at Cys(384) in the cytoplasmic B domain. (Mus musculus) PubMed

 6457.

Overexpression of ERG11, CDR1 and CDR2 genes is associated with the increase of fluconazole resistance in clinical isolates of C. glabrata. [CDR1; CDR2] (Mus musculus) PubMed

 6458.

The four phtosynthetic FNR protein isoforms are each present in the chloroplast in phosphorylated and non-phosphorylated states.[FNR] (Mus musculus) PubMed

 6459.

The cloning and characterization of two solanesyl diphosphate synthase genes, OsSPS1 and OsSPS2, in Oryza sativa is reported here. [OsSPS1 and OsSPS2] (Mus musculus) PubMed

 6460.

The data support a model in which AnhE acts as a dimeric metallochaperone to deliver cobalt to ANHase. [AnhE] (Mus musculus) PubMed

 6461.

The present study investigates the cascade components at the higher integrated level of Sorghum bicolor leaf discs and leaves. PEPC-k up-regulation required light and photosynthetic electron transport.[PEPC-k. PLD] (Mus musculus) PubMed

 6462.

Mutation of sarA resulted in a reduced capacity to form a biofilm in all clinical isolates irrespective of the functional status of agr.[sarA, agr] (Mus musculus) PubMed

 6463.

The structure of scpB-lmb intergenic region in 111 GBS isolates belonging to the intraspecies major clonal complexes (CCs).[scpB, lmb] (Mus musculus) PubMed

 6464.

Xac catalase-specific activity is induced during the stationary phase of growth in parallel with the bacterial resistance to peroxide challenge.[KatE] (Mus musculus) PubMed

 6465.

Enterocin X, composed of peptides (Xalpha and Xbeta), is a novel class IIb bacteriocin of strain KU-B5, which displays variably enhanced or reduced antibacterial activity compared to each peptide individually. [enterocin X] (Mus musculus) PubMed

 6466.

Both cyclin C and Cdk8 are regulated during development in response to extracellular signals and the levels of these proteins are important in controlling the timing of developmental processes.[Cyclin C] (Mus musculus) PubMed

 6467.

the role of acidic amino acid residues (Mus musculus) PubMed

 6468.

Our results suggest that cAMP-CRP-mediated downregulation of phage adsorption may contribute to a mechanism for the V. cholerae O1 strains to survive predation by multiple environmental phages. [CRP] (Mus musculus) PubMed

 6469.

physicochemical properties and crystal structure of cytochrome c(554)[cytochrome c554] (Mus musculus) PubMed

 6470.

The phylogeny of GimA was unravelled and investigate its island character was investigated.[GimA] (Mus musculus) PubMed

 6471.

both RpoS and OxyR are required to promote expression of both the katG-dpsA operon and dpsA gene. [RpoS, OxyR, katG, dpsA] (Mus musculus) PubMed

 6472.

examine the transcriptional regulator Wor1, a master regulator of white-opaque switching in the human fungal pathogen Candida albicans; involves an unusual coupling between two dissimilar, covalently linked domains (Mus musculus) PubMed

 6473.

We cloned a bacterial copper-containing nitrite reductase (NirK) homolog gene of Aspergillus oryzae (AonirK). [AonirK] (Mus musculus) PubMed

 6474.

In this study, we cloned and sequenced cDNA and genomic DNA carrying ocpO encoding carboxypeptidase O. [carboxypeptidase O] (Mus musculus) PubMed

 6475.

affects colonization by Fusarium spp. [caffeic acid O-methyltransferase] (Mus musculus) PubMed

 6476.

GAP-43 protein expression in airway afferent neurons can be induced by allergic airway inflammation. (Mus musculus) PubMed

 6477.

The overall morphology of the strain carrying the un-7 mutation is compared to strains carrying the png-1 mutation and these mutations are evaluated in the context of other temperature-sensitive mutants in Neurospora.[png-1, un-7] (Mus musculus) PubMed

 6478.

Genetic partners of Rps15p were identified in Saccharomyces cerevisiae and elucidate the role of Rps15 during ribosomal biogenesis, was elucidated.[Rps15p] (Mus musculus) PubMed

 6479.

The presented data, which was obtained in the test-tube experiments, adds GCN4 and c-Jun to the pool of proteins with multiple functions.[GCN4] (Mus musculus) PubMed

 6480.

Neurokinin B acts via the neurokinin-3 receptor in the retrochiasmatic area to stimulate luteinizing hormone secretion. [Neurokinin 3 receptor, sheep] (Mus musculus) PubMed

 6481.

The structural plasticity of gp120 can accommodate multiple modes of antibody binding within the CD4 binding site.[gp120] (Mus musculus) PubMed

 6482.

Show that repeated duplication events have led to at least five carnitine palmitoyltransferase I (CPT I) isoforms in rainbow trout. (Mus musculus) PubMed

 6483.

presents the structure of the par toxin Fst, the first atomic resolution structure of a component of an antisense regulated toxin-antitoxin system; and mode of membrane binding was determined by epr and molecular dynamics simulation [Fst] (Mus musculus) PubMed

 6484.

The crystal structure at 2.3 A resolution of the carboxyltransferase domain of yeast ACC in complex with tepraloxydim, is reported.[ACC] (Mus musculus) PubMed

 6485.

Mutations at positions 186 and 194 in the HA gene of the H1N1 influenza virus improve virus replication. [HA] (Mus musculus) PubMed

 6486.

1.9 A crystal structure of the HDV ribozyme shows the HDV ribozyme may use a combination of metal ion Lewis acid and nucleobase general acid strategies to effect RNA cleavage. (Mus musculus) PubMed

 6487.

The data indicate that Verotoxin 2 (VT2) plays a role in the adherence of EHEC O157:H7 to intestinal epithelial cells, possibly by increasing the expression of the host receptor beta1-integrin. [VT2] (Mus musculus) PubMed

 6488.

The SO3177 gene, encoding a putative formyltransferase and situated in a cell surface polysaccharide biosynthesis gene cluster, was responsible for the increased currentn and affects cell adhesion to graphite anodes. (Mus musculus) PubMed

 6489.

mRNPs containing TcDHH1 are involved in mRNA metabolism, regulating the expression of at least epimastigote-specific genes[TcDHH1] (Mus musculus) PubMed

 6490.

Med8, Med18, and Med20 can fold in different ways to form both soluble monomeric proteins and different distinct subcomplexes.[Med8, Med18, Med20] (Mus musculus) PubMed

 6491.

discovered two patches of residues-one on H3 and a second on H4-that are crucial for sporulation but not critical for mitotic growth, and likely comprise interactive nucleosomal surfaces[histone H3 and Histone h4; strain is SK1] (Mus musculus) PubMed

 6492.

In addition to their role in initiation, Ligatin and MCT-1/DENR can promote release of deacylated tRNA and mRNA from recycled 40S subunits after ABCE1-mediated dissociation of post-termination ribosomes[MCT-1,DENR] (Mus musculus) PubMed

 6493.

The 165-kD crystal structure of the central domain of Sec16 in complex with Sec13 was solved at 2.7-A resolution [sec13 & sec16] (Mus musculus) PubMed

 6494.

During the acts of DNA double-strand-break repair, there is competition of DNA polymerases I, II and III with DNA Pol IV for action at the primer terminus.[DNA polymerases I, II, III, IV] (Mus musculus) PubMed

 6495.

These data indicate that RNAPII polyubiquitylation requires cooperation between distinct, sequentially acting ubiquitin ligases.[RNAPII] (Mus musculus) PubMed

 6496.

These results define the polypeptide path during SecA-mediated protein translocation.[SecA] (Mus musculus) PubMed

 6497.

The active form of Puf5 is localised to cytoplasmic foci.[Puf5] (Mus musculus) PubMed

 6498.

The data indicates that cCAT-2A is a low affinity, high velocity transporter for lysine and arginine and is the cCAT-2 isoform responsible for lysine and arginine transport in avian skeletal muscle (cationic amino acid transporter-2). (Mus musculus) PubMed

 6499.

The Escherichia coli O103 3-hydroxybutanoyltransferase gene involved in the synthesis of a Fuc3N derivative [fdhC] (Mus musculus) PubMed

 6500.

These findings suggest that the increased bacteriophage-encoded enterotoxin A (sea) expression in S. aureus caused by acetic acid induced the sea-encoding prophage, linking SEA production to the lifecycle of the phage.[sea] (Mus musculus) PubMed

 6501.

Confining Fus3 in the nucleus, via fusion to a histone H2B, reduced MAPK activation and diminished all responses (pheromone-induced gene expression, cell cycle arrest, projection formation, and mating). [Fus3] (Mus musculus) PubMed

 6502.

The geometry of the axial ligands of the hemes in the triheme cytochrome PpcA from Geobacter sulfurreducens was determined in solution for the ferric form.[PpcA] (Mus musculus) PubMed

 6503.

Transcription of chpA was dependent on chpR, a CadC family transcriptional regulator located upstream of, and divergently transcribed from, chpAB.[chpR] (Mus musculus) PubMed

 6504.

IDEF1 and IDEF2 are constitutively expressed during both vegetative and reproductive stages. The spatial expression patterns of IDEF1 and IDEF2 overlap with their target genes in restricted cell types, but not in all cells. [IDEF1] (Mus musculus) PubMed

 6505.

OsCIPK14 and OsCIPK15 interact with Ca2+ sensor proteins and are involved in microbial defense responses, including hypersensitive cell death, mitochondrial dysfunction, phytoalexin biosynthesis, and pathogenesis-related gene expression. [CIPK14; CIPK15] (Mus musculus) PubMed

 6506.

The AnBud3-Rho4 module acts downstream of the septation initiation network to mediate recruitment of the formin SepA to the site of contractile actin ring assembly.[Bud3, Rho4] (Mus musculus) PubMed

 6507.

A new FeEnt receptor CfrB was indentified and characterized using both in vitro and in vivo systems. [CfrB] (Mus musculus) PubMed

 6508.

OsPHR2 physically regulates the expression of OsPT2. OsSPX1 suppresses the function of OsPHR2 in regulation of OsPT2 expression in roots. [SPX1; PT2] (Mus musculus) PubMed

 6509.

Genetic analyses with other maize mutants with variegated leaves and impaired carbohydrate partitioning suggest that Psc defines an independent pathway.[Psc] (Mus musculus) PubMed

 6510.

The Eps1 orthologous regions from rice, Aegilops tauschii, and Brachypodium distachyon were compared as part of current efforts to clone this gene.[Eps-1] (Mus musculus) PubMed

 6511.

Our 3-D structure results of the Dihydropyridine receptor propose a model in which the beta subunit may regulate ion channel function by acting as a hinge between alpha(1) and alpha(2)delta subunits of the DHPR. [DHPR] (Mus musculus) PubMed

 6512.

Ssl3076 protein (GgpR) represses ggpS expression under low-salt conditions, whereas in salt-shocked and salt-acclimated cells a stress-proportional ggpS expression occurs, leading to glucosylglycerol accumulation. [GgpR] (Mus musculus) PubMed

 6513.

SspB, particularly in the presence of staphylococcal protein A, may reduce the number of functional phagocytes at infection sites, thus facilitating colonization and dissemination of S. aureus.(SspB) (Mus musculus) PubMed

 6514.

Stn1 interacts with Ten1 through an alpha-helix, in a manner analogous to the interaction between the comparable subunits of the replication protein A complex.[Stn1, Ten1] (Mus musculus) PubMed

 6515.

In hxk2 deletion mutant CEN.PK, growth rate collapses and derepression occurs on the physiological level, while the hxk2 deletion mutant S288C descendant FY4 still grows like the parent strain and shows a fully repressed metabolism.[HXK2] (Mus musculus) PubMed

 6516.

The proximal consequence of LTV1 mutations is inhibition of the cytoplasmic maturation of 40S subunits and nuclear retention of pre-40S subunits is a downstream consequence of the failure to release and recycle critical factors back to the nucleus.[Ltv1] (Mus musculus) PubMed

 6517.

Swm2p is required for a substrate-specific activity of Tgs1p.[Tgs1, Swm2] (Mus musculus) PubMed

 6518.

Cleavage of HA by plasmin control the virulence of H1N1 influenza virus.[HA] (Mus musculus) PubMed

 6519.

PB2 associates with CCT2 as a monomer and the CCT binding site is located in a central region of the PB2 protein. . [PB2] (Mus musculus) PubMed

 6520.

Tyrosine residue at position 76 of M2 was critical for the formation of infectious virus particles. [M2] (Mus musculus) PubMed

 6521.

M2 protein cholesterol recognition/interaction amino acid consensus (CRAC) motif is a virulence determinant which may facilitate virus replication in vivo but is not required for basic virus replication in tissue culture. [M2 protein] (Mus musculus) PubMed

 6522.

Fitness epistasis among amino acids of a functionally important region of the human immunodeficiency virus type 1 (HIV-1) exterior envelope glycoprotein (gp120), was investigated.[gp120] (Mus musculus) PubMed

 6523.

A major function of RecG is to curb potentially pathological replication initiated via PriA protein at sites remote from oriC.[RecG, RuvA, RuvB, RuvC] (Mus musculus) PubMed

 6524.

AgsA regions for lysozyme chaperone activity are located outer surface of the oligomeric complex while those regions important for insulin are located inside the oligomeric complex and those for MDH are located within the N-terminal arm. (AgsA) (Mus musculus) PubMed

 6525.

CbaX displays typical features of a generic Surf1 factor essential for binding and positioning the heme a moiety for correct assembly into the protein scaffold of oxidase subunit I. [CbaX] (Mus musculus) PubMed

 6526.

These results suggest that ttcsp2 mRNA acts as a 'thermosensor' that responds to temperature downshift by changes in its own secondary structure. (ttcsp2) (Mus musculus) PubMed

 6527.

This work suggests that, although NRG1 repression plays a key role in regulating true hyphal growth, it apparently does not regulate pseudohyphal growth in the same fashion.[NRG1] (Mus musculus) PubMed

 6528.

The human cytomegalovirus microRNA miR-UL112 was found to act synergistically with cellular microRNA to escape immune elimination. (Mus musculus) PubMed

 6529.

A single mutation in hfq was responsible for the multiple benefits under glucose limitation through changes in at least five regulation targets. [Hfq] (Mus musculus) PubMed

 6530.

Triticum aestivum-5B2 (( Ta ) 5B2) is suggested to be a wheat analogue of human CDK2 enzyme.[5B2] (Mus musculus) PubMed

 6531.

These data indicate that TaNF-YC11 is potentially involved in regulation of photosynthesis-related genes.[TaNF-YC11] (Mus musculus) PubMed

 6532.

analysis of differences in large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4 [KCC4/SLC12A7] (Mus musculus) PubMed

 6533.

the pK(a) values of each of the imidazole rings of the two ligating histidines (His134 and His154) in the oxidized and reduced states of the Rieske protein [Rieske protein] (Mus musculus) PubMed

 6534.

Maternal deprivation affects the intraneuronal locations involved in the maturation of GnRH from proGnRH in the preoptic area-hypothalamus of weanlings.[GAP] (Mus musculus) PubMed

 6535.

This study concluded that VjbR and N-dodecanoyl homoserine lactone signaling molecule (C12-HSL) contribute to virulence and survival by regulating expression of virulence mechanisms.[C12-HSL] (Mus musculus) PubMed

 6536.

Ciona heart ANP might play a similar role like in the heart of vertebrates.[ANP] (Mus musculus) PubMed

 6537.

YCF45 protein is targeted into the mitochondrion but not plastids. [YCF45] (Mus musculus) PubMed

 6538.

Interaction of UL112-113 with UL44 is necessary for efficient viral DNA replication. [UL113] (Mus musculus) PubMed

 6539.

An htrA mutant had 20-23% less growth than an htrA-complemented strain of S. mutans K7 under acidic conditions.When the htrA expression level was restored, the normal growth phenotype was restored under acid stress. HTRA. (Mus musculus) PubMed

 6540.

These results indicate that the vital role of both Sal1p and Aac2p is to maintain the essential intramitochondrial ATP pool owing to their ability to transport adenine nucleotides.[Sal1 & Aac2] (Mus musculus) PubMed

 6541.

The putative N-peptide binding area in Sec1p domain 1 is important for Mso1p binding, and Mso1p can interact with Sso1p and Sso2p.[Sec1p, Mso1p] (Mus musculus) PubMed

 6542.

SSD1 controls plant elongation by controlling cell division in higher plants.[SSD1] (Mus musculus) PubMed

 6543.

One gene candidate, TcAAAP411, was characterized as a very specific, high-affinity, l-arginine permease.[AAAP411] (Mus musculus) PubMed

 6544.

examination of the DNA binding thermodynamics of Klenow and Klentaq to different DNA structures [DNA polymerase I] (Mus musculus) PubMed

 6545.

novel insights into the molecular structure of OmcA in solution and its interaction with insoluble hematite and small organic ligands [OmcA] (Mus musculus) PubMed

 6546.

The BTas transactivator contains two major functional domains: the N-terminal DNA-binding domain (residues 1-133) and the C-terminal activation domain (residues 198-249). [Ttas] (Mus musculus) PubMed

 6547.

trimeric state and monomeric state of EhCaBP1 [EhCaBP1] (Mus musculus) PubMed

 6548.

We showed MDV pUL49.5 down-regulates MHC class I directly and identified its cytoplasmic tail as essential for this function. [UL49.5] (Mus musculus) PubMed

 6549.

IgT, an immunoglobulin isotype of unknown function, acts like a mucosal antibody [IgT] (Mus musculus) PubMed

 6550.

the effect of membrane thickness on prestin [prestin] (Mus musculus) PubMed

 6551.

The newly described Lip2 has 43 kDa molecular weight, C8 substrate specificity and optimal reaction temperature of 50 degrees C.[Lip2] (Mus musculus) PubMed

 6552.

Purification and characterization of mycoferritin [mycoferritin] (Mus musculus) PubMed

 6553.

Purified SnrA and cnr were investigated for their capacity to activate several mutagens in the Ames test as well as their kinetic parameters K(m) and V(max).[SnrA, cnr] (Mus musculus) PubMed

 6554.

OsGA2ox6 mainly affects plant stature, and the dominant dwarf trait of the H032 mutant can be used as an efficient dwarf resource in rice breeding.[OsGA2ox6] (Mus musculus) PubMed

 6555.

PDA1 is required for post-meiotic tapetal development and pollen/microspore formation in rice.[PDA1] (Mus musculus) PubMed

 6556.

SMS1 gene will be a novel gene that regulates the two developmental processes.[SMS1] (Mus musculus) PubMed

 6557.

MIP1 interacted with MOC1 both in vitro and in vivo {MIP1 & MOC1] (Mus musculus) PubMed

 6558.

This study identifies CRL4Cdt2 as the ubiquitin ligase for Xic1 in the egg.[CRL4Cdt2] (Mus musculus) PubMed

 6559.

A model of HisK:GalR is proposed to explain how galactose mediates the expression of the gal operon in T. tengcongensis. [HisK, GalR] (Mus musculus) PubMed

 6560.

osmads34 mutants developed altered inflorescence morphology, with an increased number of primary branches and a decreased number of secondary branches, and displayed a decreased spikelet number and altered spikelet morphology. (Mus musculus) PubMed

 6561.

These data indicate that 53R is an essential viral protein that is required for replication in vitro and suggest it plays a critical role in virion formation. [53R] (Mus musculus) PubMed

 6562.

The C-terminal extension is responsible for redox regulation of ZmGLYK. [GLYK] (Mus musculus) PubMed

 6563.

Gene expression of Xyl1, but not Xyl2 and Xyl3, is induced by xylose. [Xyl1,Xyl2,Xyl3] (Mus musculus) PubMed

 6564.

K5 lyase KflA combines a viral tail spike structure with a bacterial polysaccharide lyase mechanism [KflA] (Mus musculus) PubMed

 6565.

In conclusion, these data reinforce the notion that Helicobacter pylori neutrophil-activating protein has a pivotal role in sustaining a prolonged activation of monocytes and neutrophils. (Mus musculus) PubMed

 6566.

The authors conclude that ATG9 and hence macroautophagy has a protective role during pathogen infection.[ATG9] (Mus musculus) PubMed

 6567.

The activities of Bim1 and Bik1, two +TIP proteins from budding yeast and members of the EB1 and CLIP-170 families, respectively, are described.[Bim1, Bik1] (Mus musculus) PubMed

 6568.

Mdm38 and Mba1 exhibit overlapping regulatory functions in translation of selected mitochondrial mRNAs.[Mdm38 and Mba1] (Mus musculus) PubMed

 6569.

The reversible association of RCA with the thylakoid membrane is ATP and pH. [RCA] (Mus musculus) PubMed

 6570.

Calflagin inhibition prolongs host survival and suppresses parasitemia in Trypanosoma brucei infection (Mus musculus) PubMed

 6571.

TbPRMT6 is a type I protein arginine methyltransferase that contributes to cytokinesis in Trypanosoma brucei (Mus musculus) PubMed

 6572.

extension of NS1 to 230 aa had no impact on replication; minimal effects on replication, pathogenicity and transmission observed in animal model; data suggest 2009 H1N1 virus optimized to replicate efficiently without requiring certain NS1 functions[NS1] (Mus musculus) PubMed

 6573.

Under ex vivo conditions, CaGto1 and CaGtt11 become transitorily upregulated inside macrophages and neutrophils.[Gto1 & Gtt11] (Mus musculus) PubMed

 6574.

A Plasmodium falciparum transcriptional cyclin-dependent kinase-related kinase with a crucial role in parasite proliferation associates with histone deacetylase activity (Mus musculus) PubMed

 6575.

OSIAGP codes for an arabinogalactan protein homologue, and its promoter contains several pollen-specificity and light-regulatory elements active during pollen development and pollen tube growth. [OSIAGP] (Mus musculus) PubMed

 6576.

crystal structure provides a possible unification of the discrete site versus continuum conduction models (M2 proton channel) (Mus musculus) PubMed

 6577.

Analysis of lacZ expression in several deletion mutants confirmed that the effect of Snf7p on anaerobic upregulation of TIR1 involved Rim101p.[Snf7, TIR1 & Rim101] (Mus musculus) PubMed

 6578.

OXP1/YKL215c, an uncharacterized open reading frame of Saccharomyces cerevisiae, encodes a functional ATP-dependent 5-oxoprolinase of 1286 amino acids.[OXP1] (Mus musculus) PubMed

 6579.

data suggest a role for RfxA in linking cellular division with morphogenesis, particularly during conidiation and yeast growth [RfxA] (Mus musculus) PubMed

 6580.

study reports that CaNdt80p is indeed required for hyphal growth in response to different filament-inducing cues and for the proper expression of genes characterizing the filamentous transcriptional program [Ndp80] (Mus musculus) PubMed

 6581.

These data show that Rck2p regulates cellular responses to cell wall stresses, filamentation and virulence in the human fungal pathogen Candida albicans.[Rck2] (Mus musculus) PubMed

 6582.

Suppression of the C. elegans thioredoxin orthologs trx-1 and trx-2, involved in the redox chaperone activity of exo-3, overrides the protective effect of cep-1 RNAi treatment on neuronal integrity, neuronal function, mean and maximum life span.[TRX-2] (Mus musculus) PubMed

 6583.

Lysine 161 is not absolutely essential for catalysis.[DHDPS] (Mus musculus) PubMed

 6584.

MtsR is a global regulator in GAS that shapes the expression of vital virulence factors and genes involved in metabolic functions and metal transport, and we discuss the implications for the GAS disease process.(MtsR) (Mus musculus) PubMed

 6585.

These results demonstrate that TSRF1 enhances the osmotic and drought tolerance of rice by modulating the increase in stress responsive gene expression.[TSRF1] (Mus musculus) PubMed

 6586.

Inhibition of gliding motility without inhibition of micronemal secretion by 1NM-PP1 suggests a function for Toxoplasma gondii CDPK1 in gliding motility. (Mus musculus) PubMed

 6587.

Subdomain 3 of Plasmodium falciparum VAR2CSA DBL3x is a minimal chondroitin sulfate A-binding region [VAR2CSA] (Mus musculus) PubMed

 6588.

IE62 has two critical but discrete roles following varicella zoster virus entry: to induce expression of viral genes and to disarm the interferon-dependent antiviral defense through a novel mechanism that prevents IRF3 phosphorylation.[IE62] (Mus musculus) PubMed

 6589.

Rrp46 forms a homodimer separately from exosome complexes and, dimeric oRrp46 had both phosphorolytic RNase and hydrolytic DNase activities and is a component of the machinery that cleaves DNA during apoptosis[Rpr46] (Mus musculus) PubMed

 6590.

Data show that T. brucei possesses a member of the Trk/HKT superfamily of monovalent cation permeases, HKT1, which so far had only been known from bacteria, archaea, fungi, and plants [HKT1]. (Mus musculus) PubMed

 6591.

Artemisinin resistance in western Cambodia is not linked to pfATPase6, as was suggested by earlier studies. [pfATPase6] (Mus musculus) PubMed

 6592.

SERA1 and SERA2 loss-of-function lines progressed normally through the parasite life cycle, suggesting a specialized, non-vital role for serine-type SERAs in vivo.[SERA1 and SERA2] (Mus musculus) PubMed

 6593.

Isogenic hla-negative (Deltahla) strains caused skin lesions in a mouse infection model that were significantly smaller than those caused by wild-type USA300 [hla] (Mus musculus) PubMed

 6594.

enzyme activity of aglC [aglC] (Mus musculus) PubMed

 6595.

Study identified a mosGCTL-1 homolog, CPIJ010995, and found that silencing it reduced the WNV burden compared to the control group suggesting that Culex mosGCTL-1 plays a role in facilitating WNV infection in Culex mosquitoes.[CPIJ010995, Culex mosGCTL-1] (Mus musculus) PubMed

 6596.

Data show that the transcriptional activity of Neurog3 affects migration and differentiation of ectopic endocrine cells in chicken endoderm. [Neurog3] (Mus musculus) PubMed

 6597.

Localization and targeting of an unusual pyridine nucleotide transhydrogenase in Entamoeba histolytica (Mus musculus) PubMed

 6598.

Data demonstrate that DBF-2 is involved in three fundamental processes in a filamentous fungus: cell cycle regulation, glycogen biosynthesis, and conidiation, and functions as a link between Hippo and glycogen metabolism pathways. (Mus musculus) PubMed

 6599.

The authors propose that PIF1, PIF2, PIF3, and P74 form an evolutionarily conserved complex on the occlusion-derived virus surface, which has an essential function in the initial stages of baculovirus oral infection.[PIF1, PIF2 & PIF3] (Mus musculus) PubMed

 6600.

Mutations in the middle of the M53 open reading frame (ORF) resulted in dominant negative mutants inhibiting virus replication by approximately 100-fold, mutations at the C terminus resulted in up to 1,000,000-fold inhibition of virus production.[M53] (Mus musculus) PubMed

 6601.

Cif deamidated NEDD8, which abolished activity of neddylated Cullin-RING ubiquitin ligases (CRLs); ubiquitination and ubiquitin-dependent degradation of CRL substrates were impaired by Cif in EPEC-infected cells [Cif] (Mus musculus) PubMed

 6602.

PB1-F2 protein has various lengths, amino acid sequences, cellular localizations, and functions in different strains, which result in strain-specific pathogenicity. (Mus musculus) PubMed

 6603.

findings show CHBP was a potent inhibitor of the eukaryotic ubiquitination pathway; CHBP acted as a deamidase that specifically and efficiently deamidated Gln40 in ubiquitin and ubiquitin-like protein NEDD8 in vitro and during Burkholderia infection[CHBP] (Mus musculus) PubMed

 6604.

These results suggest a division of labor between Isw1 and Isw2, whereby Isw2 maintains repressive chromatin structure at gene ends while Isw1 has a similar function at mid-coding regions.[Isw1] (Mus musculus) PubMed

 6605.

results suggest that human-derived mutations in HA of H5N1 viruses can affect viral replication efficiency and organ tropism [HA] (Mus musculus) PubMed

 6606.

L35 assembles in the nucleolus and binds to early pre-60S ribosomal particles (L35). (Mus musculus) PubMed

 6607.

Data show that Rac1 and betaPIX are indirect targets of NS5 acting through the multifunctional polarity protein Scribble to oppose neuronal differentiation [NS5]. (Mus musculus) PubMed

 6608.

Redox titration analysis revealed that the midpoint reduction potential of OmcZ(S) is approximately -220 mV (versus the standard hydrogen electrode [SHE]) with nonequivalent heme groups that cover a large reduction potential range (-420 to -60 mV).[OmcZ] (Mus musculus) PubMed

 6609.

The authors show that the P1 domain is sufficient to determine which response regulators will be phosphorylated in vitro while the P5 domain is sufficient to localize the CheAs to a specific chemosensory cluster.[CheA2, CheA3 & CheA4] (Mus musculus) PubMed

 6610.

MoTea4 plays an important role in organizing the F-actin cytoskeleton and is essentially required for polarized growth and morphogenesis during asexual and pathogenic development in Magnaporthe.[MoTea4] (Mus musculus) PubMed

 6611.

report an all-atom model of the macromolecular structure of Panton-Valentine leukocidin in its octameric, pre-pore conformation that confirms and extends our understanding of the toxin's mechanism of action [LukF, LukS] (Mus musculus) PubMed

 6612.

This study investigates the time-resolved reaction between fully reduced ba3 Cytochrome c oxidase and O2 in variants where Thr-312 and Thr-315 were modified.[ba3 Cytochrome c oxidase] (Mus musculus) PubMed

 6613.

These findings indicate that close interaction between adhesive and anchoring pilin domains of CfaE keeps the former in a low-affinity state that toggles into a high-affinity state upon separation of two domains.[CfaE] (Mus musculus) PubMed

 6614.

Physical interaction between CP and HC-Pro is important for potyviral aphid transmission.[Coat protein] (Mus musculus) PubMed

 6615.

Transcription of the nagF and nagE2 genes is induced by N-acetylglucosamine.[nage2] (Mus musculus) PubMed

 6616.

Disruption of the CIN1 gene had a pleiotropic effect on growth, cytokinesis, intracellular transports and the production of virulence factors. [Cin1] (Mus musculus) PubMed

 6617.

show that the intra-antenna energy transfer processes in CP43 and CP47 are surprisingly fast[CP47] (Mus musculus) PubMed

 6618.

FgPTC1 plays an important role in regulating the hyphal growth and virulence of F. graminearum.[FgPTC1] (Mus musculus) PubMed

 6619.

P-body formation is disrupted in strains with deleted Edc3(enhancer of decapping) or CutA (encodes a nucleotidyltransferase); the signalled degradation of specific transcripts are dependent on nuclease activity of Caf1 but not Ccr4[Edc3,CutA, Caf1,Ccr4] (Mus musculus) PubMed

 6620.

Data indicate that the activity of SpGH38 alpha-mannosidase, together with its genomic context strongly hints at a function in the degradation of host N- or possibly O-glycans: [GH38 alpha-mannosidase] (Mus musculus) PubMed

 6621.

These results suggested that the double silencing of cytosolic OsApx genes induced compensatory antioxidant mechanisms in rice while single knockdown of these genes did not, which resulted in the impairing of normal plant development. [Apx1 and Apx2] (Mus musculus) PubMed

 6622.

the pollen disrupted for OsSUT1 is dysfunctional, however, starch accumulation during pollen development was not affected by disruption of OsSUT1 [SUT1] (Mus musculus) PubMed

 6623.

Deleting ARP2 abolished hyphal formation, generated round and swollen yeast phase cells, disrupted cortical actin patches and blocked virulence in mice.[ARP2] (Mus musculus) PubMed

 6624.

Study identified genes that are expressed in a monopolar cell (Amfutsch and Amtau) or ventral medulla-preferential manner (AmMESK2) in insect OLs: [Amfutsch, Amtau and AmMESK2] (Mus musculus) PubMed

 6625.

The crystal structure of the urease maturation protein UreE from Helicobacter pylori has been determined in its apo form at 2.1 A resolution, bound to Cu(2+) at 2.7 A resolution, and bound to Ni(2+) at 3.1 A resolution. [UreE] (Mus musculus) PubMed

 6626.

Reresults indicate that QDE-1 displays five distinct catalytic activities, which can be dissected by mutating critical amino acids or by altering reaction conditions. [QDE-1] (Mus musculus) PubMed

 6627.

Glyoxalase I (GloI) and one of the two glyoxalases II (cGloII) were located in the cytosol of the blood stages. The second glyoxalase II (tGloII) was detected in the apicoplast pointing to alternative metabolic pathways.[GloI & GloII] (Mus musculus) PubMed

 6628.

root-yield-1.06 has a major constitutive effect on root traits, plant vigour and productivity across water regimes, genetic backgrounds, and inbreeding levels [root-yield-1.06] (Mus musculus) PubMed

 6629.

Overexpression of the TcPOT1.1 and TcPOT1.2 genes in T. cruzi epimastigotes revealed that TcPOT1.1 and TcPOT1.2 were high-affinity transporters that recognized both putrescine and cadaverine but not spermidine or spermine.[POT1.1 & POT1.2] (Mus musculus) PubMed

 6630.

Data show that the PfSERCA (PfATP6) functional domains were very well conserved, with non synonymous mutations located outside the functional domains: [PfATP6] (Mus musculus) PubMed

 6631.

The authors show that FlbB activates the expression of FlbD, both factors then jointly activate brlA, a C(2)H(2) zinc finger transcription factor, which plays a central role in spore formation.[FlbB, FlbD & brlA] (Mus musculus) PubMed

 6632.

Data suggest that small, non-coding RNA EBER1 plays an oncogenic role in EBV associated malignant disease: [EBER1] (Mus musculus) PubMed

 6633.

The presence of cagE and virB11 cag pathogenicity island genes shows that they are important factors for the pathogenesis and malignancy of gastric cancer related to H. pylori. [cagE, virB11] (Mus musculus) PubMed

 6634.

Results report the crystal structure of the MID domain of the eukaryotic Argonaute protein QDE-2 from Neurospora crassa [QDE-2]. (Mus musculus) PubMed

 6635.

Inhibition of oxidative phosphorylation perturbs sugar regulation of Amy3D expression in the embryo. [Amy3D] (Mus musculus) PubMed

 6636.

kch1 insertion mutants show impaired cell expansion and increased division. KCH overexpression delays nuclear positioning and mitosis. [KCH1] (Mus musculus) PubMed

 6637.

Near-optimal catalytic properties are observed for diacylglycerol kinase in micelles composed of lysomyristoylphosphatidylcholine. [diacylglycerol kinase] (Mus musculus) PubMed

 6638.

BR2 is expressed in nodal meristems, and analyses of auxin transport and content indicate that BR2 function in these grass-specific tissues is analogous to ABCB1 function in the shoot and root apex of Arabidopsis [BR2] (Mus musculus) PubMed

 6639.

CBP70 is a plastid transcription elongation factor or a modulator of plastid elongation factor activity. [CBP70] (Mus musculus) PubMed

 6640.

Data suggest that OsNAC5 may be a useful gene that can improve the stress tolerance of without affecting its growth [OsNAC5] (Mus musculus) PubMed

 6641.

The authors show that Fer3, a non-ribosomal peptide synthetase, Fer4, an enoyl-coenzyme A (CoA)-hydratase, and Fer5, an acylase, are required for ferrichrome A production.[Fer3, Fer4 & Fer5] (Mus musculus) PubMed

 6642.

The effects of deleting the genes encoding ACL on growth and development, were investigated.[ATP citrate Lyase] (Mus musculus) PubMed

 6643.

This study has uncovered a multitude of novel regulatory targets of SnStuA and has highlighted the critical role of this gene product in the pathogenicity of Stagonospora nodorum.[StuA] (Mus musculus) PubMed

 6644.

GH3-1 expression increased at the onset of ripening (veraison), suggesting that it might be involved in the establishment and maintenance of low indole-3-acetic acid concentrations in ripening berries[GH3-1] (Mus musculus) PubMed

 6645.

Localization of BUD4 as a cortical ring prior to septation initiation was independent of functional BUD3 or RGF3.[BUD4, BUD3 & RGF3] (Mus musculus) PubMed

 6646.

A knockout mutation in OsCOL4 causes early flowering. OsCOL4 acts as a repressor upstream of Ehd1. [COL4] (Mus musculus) PubMed

 6647.

Ca(2+)/calmodulin-dependent protein kinase plays a key role in the coordinated induction of infection thread formation and nodule organogenesis. [CCaMK] (Mus musculus) PubMed

 6648.

SNL is a novel gene involved in flower development in rice.[SNL] (Mus musculus) PubMed

 6649.

Loss of MtNST1 function resulted in reduced lignin content, associated with reduced expression of most lignin biosynthetic genes, and a smaller reduction in cell wall polysaccharide content. [NST1] (Mus musculus) PubMed

 6650.

Data show that XA21 is glycosylated and is primarily localized to the ER and also to the plasma membran: [XA21] (Mus musculus) PubMed

 6651.

the biochemical and functional characterization of the protein product (Wzy) of the gene annotated as the putative O-antigen polymerase [Wzy] (Mus musculus) PubMed

 6652.

structure features of alpha-galactosidase and substrate recognition and specificity [alpha-galactosidase] (Mus musculus) PubMed

 6653.

3 SNPs were identified in field-collected mosquitoes associated with parasite infection in molecular form-dependent patterns: 2 were detected in the Toll5B gene and 1 was detected in the gene encoding insulin-like peptide 3 precursor [ILP3 precursor] (Mus musculus) PubMed

 6654.

Deletion of bovine herpesvirus 4 ORF73 did not affect the capacity of the virus to replicate in vitro, but it prevented latent infection in vivo using a rabbit model.[ORF73] (Mus musculus) PubMed

 6655.

CYP736B transcript was up-regulated in Xylella fastidiosa infection resistant plants and down-regulated in Xylella fastidiosa infection susceptible plants[CYP736B] (Mus musculus) PubMed

 6656.

Extensive mapping showed that all of the information for nuclear import resides within the small p14 protein in a bipartite nuclear localization signal composed of the signature RRKRRR and a region of the RNA recognition motif domain.[p14] (Mus musculus) PubMed

 6657.

Hfq negatively regulates the expression of tviA at early stage of hyperosmotic stress.[tviA, Hfq] (Mus musculus) PubMed

 6658.

ligand induced conformational changes in H.pylori LuxS [LuxS] (Mus musculus) PubMed

 6659.

NUE is a histone methyltransferase that targets histones H2B, H3 and H4 and itself (automethylation). [NUE] (Mus musculus) PubMed

 6660.

Data show that interaction of KtrA and KtrE with KtrB increased the K+ uptake rate and conferred Na+ dependency. [KtrA] (Mus musculus) PubMed

 6661.

The N-terminal PR domain of SpyCep was sufficient to mediate endothelial cell invasion, whereas for IL-8-degrading activity, the protease domain and the flanking A domain were required.[SpyCep] (Mus musculus) PubMed

 6662.

Analysis of mutations in the SURF1 homolog Shy1 revealed Coa4, a new member of the cytochrome oxidase assembly factor family [Coa4]. (Mus musculus) PubMed

 6663.

the Saccharomyces cerevisiae AAA-adenosine triphosphatase Cdc48 and its substrate-recruiting cofactor Shp1/Ubx1 are novel components needed for autophagosome biogenesis.[Cdc48, Shp1, Atg8] (Mus musculus) PubMed

 6664.

The bud neck-associated kinase Elm1 participates in Kin4 activation and SPOC signaling by phosphorylating a conserved residue within the activation loop of Kin4.[Elm1] (Mus musculus) PubMed

 6665.

The Atg9-positive compartments are important for the de novo formation of the phagophore assembly site and the sequestering vesicle that are the hallmarks of autophagy.[Atg9] (Mus musculus) PubMed

 6666.

The only consistent mutation in the genomes of viral clones obtained from dying mice was D225G substitution in HA. [hemagglutinin] (Mus musculus) PubMed

 6667.

Data suggest that M2 mediates the final steps of budding for influenza viruses, bypassing the need for host ESCRT proteins. [M2] (Mus musculus) PubMed

 6668.

These studies revealed that, in addition to its excellent resistance to thermal perturbations, EspP loop 5 (L5) also has remarkable mechanical stability against pulling forces along the membrane norm.[EspP] (Mus musculus) PubMed

 6669.

three crystal structures of Escherichia coli LexA in complex with SOS boxes [LexA] (Mus musculus) PubMed

 6670.

A novel Fe regulated bHLH transcription factor (OsIRO3) that plays an important role for Fe homeostasis in rice was identified[OsIRO3] (Mus musculus) PubMed

 6671.

The plasma membrane protein Sho1 interacts specifically with the MAP kinase Kpp6. Msb2 encodes a mucin-like protein. sho1 and msb2 are not required for mating and do not affect stress responses. [Sho1; Msb2] (Mus musculus) PubMed

 6672.

The low-resolution structure determined by small angle X-ray scattering indicated that AbnA is monomeric in solution and its molecular shape is in full agreement with the model.[AbnA] (Mus musculus) PubMed

 6673.

structural models of the open and closed conformations [KtrB] (Mus musculus) PubMed

 6674.

Study indicated that XdrA is a major activator of spa expression that appears to act directly on the spa promoter and not through previously characterized regulators. [XdrA] (Mus musculus) PubMed

 6675.

determined the crystal structure at 2.23 A resolution of D-Alanine:D-Alanine ligase from Streptococcus mutans [D-Alanine:D-Alanine ligase] (Mus musculus) PubMed

 6676.

the predicted ribozyme is not essential for LAT's ability to enhance the HSV-1 reactivation phenotype in mice. [LAT] (Mus musculus) PubMed

 6677.

These data support a model in which FeuN interacts directly with FeuQ to attenuate phosphorylation of FeuP, and that without this activity, hyperactive signalling through FeuPQ results in cessation of growth or death.[FeuN] (Mus musculus) PubMed

 6678.

The cloning and analysis of the jhe gene in the red flour beetle, Tribolium castaneum, a model insect of Coleoptera, is reported.[JHE] (Mus musculus) PubMed

 6679.

SbDFR1 stimulates anthocyanin accumulation and SbDFR3 stimulates -deoxyanthocyanidin production. [DFR1; DFR3] (Mus musculus) PubMed

 6680.

the complex of Tah18 and the CIA protein Dre2 is part of an electron transfer chain functioning in an early step of cytosolic Fe-S protein biogenesis [Tah18 & Dre2] (Mus musculus) PubMed

 6681.

Study reports the crystal structure of Maf1 and cryo-electron microscopic structures of Pol III, an active Pol III-DNA-RNA complex, and a repressive Pol III-Maf1 complex.[RNA Pol III] (Mus musculus) PubMed

 6682.

Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major (Mus musculus) PubMed

 6683.

replication of hepatitis C virus was inhibited by overexpression of ISG15 and NS5A was identified as the substrate for ISGylation (Mus musculus) PubMed

 6684.

The present report provides corroborating coding and additional 5' and 3' flanking sequence for three Pinb variants: Pinb-2v1, Pinb-2v2, and Pinb-2v3; additionally, a new Pinb variant, Pinb-2v4, is reported.[Pinb-2v1,Pinb-2v2, Pinb-2v3, Pinb-2v4] (Mus musculus) PubMed

 6685.

Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation (Mus musculus) PubMed

 6686.

These results suggest multiple role(s) for PfTudor-SN protein mainly in nuclear and splicing processes at asexual blood stages of the malaria parasite.[PfTudor-SN] (Mus musculus) PubMed

 6687.

The authors report that CSP-induced and basal comCDE transcription both initiate from the same promoter, P(E).[ComCDE] (Mus musculus) PubMed

 6688.

identified the predicted OB-fold as the functional domain of KREPA4 that mediates a high-affinity interaction with the gRNA oligo(U) tail (KREPA4) (Mus musculus) PubMed

 6689.

STAT3 is constitutively activated by IGF-1 in scleral fibroblasts. (Mus musculus) PubMed

 6690.

The hlyA99 mutant protein is secreted relatively efficiently but haemolytic activity is reduced. [HlyA] (Mus musculus) PubMed

 6691.

Heat shock exposure of rice seedlings for 3h in the dark was effective in reducing subsequent Cd-induced decrease in the activity of glutamine synthetase and increase in the specific activity of protease.[Glutamine synthetase] (Mus musculus) PubMed

 6692.

These data suggest that Jen1 and Jen2 are expressed in glucose-poor niches within the host, and that these short-chain carboxylic acid transporters may be important in the early stages of infection.[JEN1 & JEN2] (Mus musculus) PubMed

 6693.

TUF1 overexpression could restore respiratory growth and fluconazole sensitivity, and could suppress induction of fluconazole resistance by tetracycline treatment. [TUF1] (Mus musculus) PubMed

 6694.

A potential role of SmPlk1 in mitosis and/or meiosis in schistosomes was supported by the in situ detection of SmPlk1 transcripts in female vitelline cells and oocytes as well as in male spermatocytes.[Plk1] (Mus musculus) PubMed

 6695.

Exposure to low-dose trichloroethylene alters nitric oxide synthase 3 gene expression and function in the developing chick heart. (Mus musculus) PubMed

 6696.

Characterization of site-specific mutants of alkylhydroperoxide reductase with dual functionality [ahpC] (Mus musculus) PubMed

 6697.

Results indicate that in addition to a role in fumarate respiration, Mfr allows C. jejuni to reduce analogous substrates specifically present in the host gut environment [Mfr]. (Mus musculus) PubMed

 6698.

The central cleft of the zebrafish hatching enzyme 1 (ZHE1) represents the active site of the enzyme that is crucial for substrate recognition and catalysis.[ZHE1] (Mus musculus) PubMed

 6699.

A conserved immunoreceptor tyrosine-based inhibition motif exists in the cytoplasmic domain between transmembrane domains 7 & 8 in TM9SF5. A conserved TRAF2 binding domain is predicted in the cytoplasmic regions of TM9SF5. TM9SF5. (Mus musculus) PubMed

 6700.

Results identify a novel signaling process governing G-protein-coupled cAMP signal transduction-opposing actions of the phosphatase calcineurin and the CK1/GSK3beta protein kinases on the phosphodegron-dependent degradation of PDE4D [PDE4D]. (Mus musculus) PubMed

 6701.

DnaA utilizes at least two different oligomeric conformations for engaging single- and double-stranded DNA. [DnaA] (Mus musculus) PubMed

 6702.

Trigger factor appears to employ multiple mechanisms to interact with a wide range of substrate proteins. [TF] (Mus musculus) PubMed

 6703.

crystal structure of an amino-terminally truncated form of IpgC [IpgC] (Mus musculus) PubMed

 6704.

that CTR1 expression was inhibited at the transcriptional level through direct inhibition of the Mac1 transcriptional activator.[Mac1] (Mus musculus) PubMed

 6705.

RAVL1 participates in the maintenance of brassinosteroid homeostasis by enhancing the expression of BRI1 and several BR biosynthetic genes. (Mus musculus) PubMed

 6706.

model revealed unique structural features of TaOMT2 which permit the stepwise methylation of tricetin[-methyltransferase (TaOMT2)] (Mus musculus) PubMed

 6707.

expression of Y53A-actin, which does not affect cell growth, phagocytosis, or pinocytosis, inhibits the formation of head-to-tail cell streams during cAMP-induced aggregation, although individual amoebae chemotax normally [actin] (Mus musculus) PubMed

 6708.

the work presented here shows that are differences between Dad1 from C. albicans and S. cerevisiae. [Dad1] (Mus musculus) PubMed

 6709.

a novel post-translationally modified hemolytic toxin, clostridiolysin S [clostridiolysin S] (Mus musculus) PubMed

 6710.

a new, second gene encoding a plastid located glutamine synthetase (GS2) in M. truncatula [glutamine synthetase 2b] (Mus musculus) PubMed

 6711.

ValR, a homolog to V. harveyi LuxR, may control biofilm formation by regulating flagellar biosynthesis and affect the expression of the genes involved in colony phase variation in V. alginolyticus. [ValR] (Mus musculus) PubMed

 6712.

DnaK2 is the most abundant DnaK protein in Synechocystis, and only the expression of dnaK2 is highly up-regulated under diverse stress conditions. [DnaK2] (Mus musculus) PubMed

 6713.

These results indicate that ClpP enhances the formation of Staphylococcus epidermidis biofilms by degrading Spx, a negative regulator of biofilm formation.[Spx] (Mus musculus) PubMed

 6714.

The equine homologues of OS-9 and PSMC3 were cloned and their interactions with equine infectious anemia virus S2 protein confirmed using co-immunoprecipitation assays.[S2] (Mus musculus) PubMed

 6715.

BC12 encodes a kinesin-4 protein that shows microtubule-dependent ATPase activity. Mutation results in altered mechanical strength and reduced plant height. [BC12] (Mus musculus) PubMed

 6716.

STb and AIDA-I is associated with the pathogenicity of enterotoxigenic Escherichia coli. [AIDA-I] (Mus musculus) PubMed

 6717.

The authors identified PavB as colonization factor.[PavB] (Mus musculus) PubMed

 6718.

Sorbic acid decarboxylation also requires the activity of a putative 4-hydroxybenzoic acid decarboxylase, encoded by a gene termed ohbA1, and a putative transcription factor, sorbic acid decarboxylase regulator, encoded by sdrA.[ohbA1 & sdrA] (Mus musculus) PubMed

 6719.

A gene (CYG56) coding for a nitric oxide (NO)-dependent guanylate cyclase (GC) was interrupted in a mutant defective in repression of NIA1 and NR in response to ammonium.[sGC, NIA1] (Mus musculus) PubMed

 6720.

While gene disruption reveals that ROP13 is not essential for growth in fibroblasts in vitro or for virulence in vivo, the authors find that ROP13 is a soluble effector protein that can access the cytoplasm of host cells.[ROP13] (Mus musculus) PubMed

 6721.

arf3a transcripts hyperaccumulate but remain abaxialized in rgd2 mutant apices, revealing that trans-acting small interfering RNA -siARF function is not required for arf3a polarization.[rgd2] (Mus musculus) PubMed

 6722.

STR heterodimerizes with STR2, and the resulting transporter is located in the peri-arbuscular membrane where its activity is required for arbuscule development and consequently a functional arbuscular mycorrhizal symbiosis.[STE, STR2] (Mus musculus) PubMed

 6723.

The bacterial risk factor iceA2 seems an important predictor of severe histological changes in chronic gastritis, separately or in combination with host genetic factors in the Venezuelan population. (Mus musculus) PubMed

 6724.

Results demonstrate that trypanosomal tRNA(Sec), in contrast to its human counterpart, is transcribed by Pol-II (tRNASec). (Mus musculus) PubMed

 6725.

mitotic division, the M-phase-promoting factor amplification loop is constantly active throughout the cell cycle, and that correct regulation of PP2A activity is essential to promote normal mitosis [MPF,Greatwall]. (Mus musculus) PubMed

 6726.

Hpk2 and Rrp2 constitute a functional two-component system that contributes to environmental sensing [Hpk2, Rrp2] (Mus musculus) PubMed

 6727.

The authors found that Helicobacter pylori CheZ (CheZ(HP)) efficiently dephosphorylates CheY(HP) and CheAY and has additional weak activity on CheV2.[CheZ] (Mus musculus) PubMed

 6728.

the first crystal structure of a RihA bound to a competitive inhibitor [RihA] (Mus musculus) PubMed

 6729.

The diheme cytochrome c(4) from Vibrio cholerae is a natural electron donor to the respiratory cbb(3) oxygen reductase (Mus musculus) PubMed

 6730.

Scl1 binds the high-density lipoprotein. [Scl1] (Mus musculus) PubMed

 6731.

The Scll of M41-type GAS specifically binds LDL. [scl1] (Mus musculus) PubMed

 6732.

Mdm36-dependent formation of cell cortex anchors is required for the generation of tension on mitochondrial membranes to promote mitochondrial fission by Dnm1.[Mdm36] (Mus musculus) PubMed

 6733.

Chs3 and Ste24 form a complex in the endoplasmic reticulum that facilitates protease action on prenylated Chs4, a known activator of Chs3 with a C-terminal CaaX motif, leading to a more efficient localization of Chs3 at the plasma membrane.[Ste24] (Mus musculus) PubMed

 6734.

An MEN mutant, cdc15-2, though competent in activating the spindle assembly checkpoint when exposed to Nocodazole, mis-segregated chromosomes during recovery from spindle checkpoint activation.[cdc 15-2] (Mus musculus) PubMed

 6735.

Data suggest that Bat3 either modulates the Sec61beta/TRC40 pathway in higher eukaryotes or provides an alternative fate for newly synthesised tail-anchored proteins [Bat3]. (Mus musculus) PubMed

 6736.

Saccharomyces cerevisiae gamma-TuSC forms rings even in the absence of other gamma-TuRC components [Tub4= gamma tubulin] (Mus musculus) PubMed

 6737.

Sequence polymorphisms in LMP2A from northern Chinese EBV-associated gastric carcinoma patients, nasopharyngeal carcinoma and healthy donors shows variations in the LMP2A gene reveals classifiable sequence polymorphisms in exon 1 and exons 2-8. [LMP2A] (Mus musculus) PubMed

 6738.

These findings demonstrate that co-mutation of amino acid residues at multiple positions in the NS1 protein can increase the pathogenicity of influenza virus in mice. (Mus musculus) PubMed

 6739.

Mapping tests further demonstrated that aa 22-53 in the N-terminal region of H5N1 virus NS2 and the glycine-leucine-phenylalanine-glycine (GLFG) repeat domain (aa 1-511) of human Nup98 are crucial for the interaction of these two proteins. (Mus musculus) PubMed

 6740.

[zinc-binding protein; Z-protein] structural studies on zinc-binding protein: ligand binding to C-terminal RING domain (Mus musculus) PubMed

 6741.

[OsChia1b, class I chitinase, RCC2] crystal structure of full-length OsChia1b at 2.00-Angstrom resolution; docking simulation with tri-N-acetylchitotriose (Mus musculus) PubMed

 6742.

Deletion of the gene encoding the gamma-butyrolactone receptor homologue ScbR2 led to the discovery of a yellow pigment and an antibiotic compound. [ScbR2] (Mus musculus) PubMed

 6743.

The X-ray crystallographic analyses of apo- and complexed MalX illuminate the protein's specificity for the degradation products of glycogen and its striking ability to recognize the helical structure of the ligand.[MalX] (Mus musculus) PubMed

 6744.

The hemolysin was stable up to 40 degrees C. Only partial activity remained at 50 and 60 degrees C. [hemolysin] (Mus musculus) PubMed

 6745.

Functions of isoamylase-type starch-debranching enzyme (ISA) proteins and complexes in maize (Zea mays) endosperm were characterized.[ISA1, ISA2] (Mus musculus) PubMed

 6746.

Deletion of atg8 abolished autophagosome accumulation in the vacuoles of carbon-starved cells and drastically reduced the survival of U. maydisDeltaatg8 mutant strains during these conditions. [atg8] (Mus musculus) PubMed

 6747.

A highly conserved nuclear-encoded cGTPase of likely prokaryotic origin is essential for proper chloroplast ribosome assembly and/or translation in plants.[NOA1] (Mus musculus) PubMed

 6748.

Os03g22780, renamed as OsDVR, encodes a functional DVR in rice.[DVR] (Mus musculus) PubMed

 6749.

novel phosphoribosyltransferase transition states [Orotate Phosphoribosyltransferase] (Mus musculus) PubMed

 6750.

BmPLCbeta1, BmGq1, and unexpectedly, BmPLCgamma, are part of the PBAN signal transduction cascade.[Gq1, PLcbeta1] (Mus musculus) PubMed

 6751.

The authors showed that both ssl5 and ssl8 were induced by Sae and repressed by Agr, suggesting that Sae and Agr are the positive and the negative regulators, respectively, of these two ssl genes.[ssl8 & Agr] (Mus musculus) PubMed

 6752.

Mouse angiogenin inhibitor 1 interacts with hylA of Streptococcus suis. [hylA] (Mus musculus) PubMed

 6753.

Ltn1 is predominantly associated with ribosomes, and it marks nascent non-stop proteins with ubiquitin to signal their proteasomal degradation [Ltn1] (Mus musculus) PubMed

 6754.

By yeast two-hybrid assay, the authors found that the capsid protein (CA) of bovine immunodeficiency virus interacted with the dynein light-chain component LC8.[capsid protein] (Mus musculus) PubMed

 6755.

FINE CULM1 (FC1) partially works downstream of strigolactones to inhibit axillary bud outgrowth. [FC1] (Mus musculus) PubMed

 6756.

The findings suggest that RcsFCDB activation in response to CAMP-induced membrane disorder is a result of a change in structure or availability of RcsF to the IM signaling constituents of the Rcs phosphorelay. (Mus musculus) PubMed

 6757.

Data revealed that OdhA specifically catalyzes the E1 and E2 reaction to convert 2-oxoglutarate to succinyl-coenzyme A (CoA) but fully relies on the lipoyl residues provided by AceF involved in the reactions to convert pyruvate to acetyl-CoA.[OdhA] (Mus musculus) PubMed

 6758.

Data conclude that the StyA1/StyA2B system represents a novel type of multifunctional flavoprotein monooxygenase. [StyA1] (Mus musculus) PubMed

 6759.

The authors found that the rodent malaria parasite orthologue, Plasmodium berghei hexose transporter (PbHT) gene, was similarly refractory to knockout attempts, indicating it's essentiality.[PbHT] (Mus musculus) PubMed

 6760.

Heterologous expression of the Aspergillus fumigatus cafB, and Aspergillus nidulans canA and canB genes completely rescued the high CO(2)-requiring phenotype of a Saccharomyces cerevisiae Deltance103 mutant.[cafB] (Mus musculus) PubMed

 6761.

Heterologous expression of the Aspergillus fumigatus cafB, and Aspergillus nidulans canA and canB genes completely rescued the high CO(2)-requiring phenotype of a Saccharomyces cerevisiae Deltance103 mutant.[canA & canB] (Mus musculus) PubMed

 6762.

Based on these data, the authors propose that POLIB performs an essential role at the core of the minicircle replication machinery.[POLIB] (Mus musculus) PubMed

 6763.

These data indicate that Arl2 has a fundamentally conserved role in trypanosome microtubule biogenesis that correlates with alpha-tubulin acetylation.[Arl2] (Mus musculus) PubMed

 6764.

dupA promotes duodenal ulceration in some populations and GU and GC in others. This is typical of other virulence factors, such as cagA. Hence, it was concluded that the H. pylori virulence factor, dupA, is a true virulence factor.[dupA](Meta-Analysis) (Mus musculus) PubMed

 6765.

V. vulnificus produce outer membrane vesicles that can induce host cell death and this process is mediated by VvhA. [VvhA] (Mus musculus) PubMed

 6766.

Analysis of protein interactions showed that K179A, K180A, and K221A substitutions of classical swine fever virus core protein disrupt core-SUMO-1 binding, while K220A substitution precludes core-UBC9 binding.[core protein] (Mus musculus) PubMed

 6767.

The expression of the spliced form of YlHAC1 mRNA in the wild-type andDeltaYlhac1 strains resulted in an increased resistance to DTT, thereby indicating that the spliced form is translated into a functional YlHac1p.[HAC1] (Mus musculus) PubMed

 6768.

Overexpression of ZmWRI1 results in an oil increase similar to overexpression of ZmLEC1 without affecting germination, seedling growth, or grain yield.[ZmWRI1] (Mus musculus) PubMed

 6769.

Expression of Bs1 is tightly controlled and occurs during a narrow developmental window in early ear development.[Bs1] (Mus musculus) PubMed

 6770.

sequence, linkage, association and expression analyses collectively showed that the two maize genes represent chromosomal duplicates, which function to control some of the phenotypic variation for kernel size and weight [ZmGW2-CHR4 and ZmGW2-CHR5] (Mus musculus) PubMed

 6771.

expression of orfH79 in mitochondria impairs mitochondrial function, which affects the development of both male gametophytes and the roots of CMS-HL rice [orfH79; CMS-HL line] (Mus musculus) PubMed

 6772.

a gene encoding a nucleotide binding site (NBS) and leucine rich repeat (LRR) domain-containing (NBS-LRR) protein encodes Pish, which confers resistance against races of Magnaporthe oryzae containing avrPish (Mus musculus) PubMed

 6773.

the first report that the cholesterol binding ability may directly correlate with AeSCP-2's in vivo function in aiding the uptake of cholesterol (Mus musculus) PubMed

 6774.

promiscuous TtHICDH was evolved into an enzyme showing distinct IPMDH activity by directed evolution using a DNA-shuffling technique[homoisocitrate dehydrogenase ] (Mus musculus) PubMed

 6775.

BiP binding to Ire1 serves to desensitize Ire1 to low levels of stress and promotes its deactivation when favorable folding conditions are restored to the endoplasmic reticulum.[Ire1, BiP] (Mus musculus) PubMed

 6776.

The finding that both mitochondrial AAC proteins and the vacuolar Pep4p interfere with mitochondrial degradation suggests a complex regulation and interplay between mitochondria and the vacuole in yeast programmed cell death.[AAC] (Mus musculus) PubMed

 6777.

expressed in the ovary throughout early fetal stages to adulthood [BMP1] (Mus musculus) PubMed

 6778.

Group B Streptococcus with decreased CovR function show a dramatic increase in their ability to cause bloodstream infections, activate innate immune signalling pathways and penetrate the blood-brain barrier. [CovR] (Mus musculus) PubMed

 6779.

Because of the role of ARD in the methionine salvage pathway, these results suggest that TaARD (aci-reductone-dioxygenase) may be involved in ethylene synthesis and ethylene signaling in response to biotic and abiotic stresses. (Mus musculus) PubMed

 6780.

Expressed chitinases from S. marcescens GEI by recombinant Escherichia coli showed pathogenicity against Varroa destructor in the laboratory [ChiA; ChiB; ChiC1] (Mus musculus) PubMed

 6781.

These studies provide clear evidence that SpyCEP is necessary and sufficient for systemic bacterial dissemination from a soft tissue focus in this model and also underlies dissemination in the respiratory tract.[CEP] (Mus musculus) PubMed

 6782.

BmTCTPk may play an important role during the developmental transition from pupa to imago.[TCTPk] (Mus musculus) PubMed

 6783.

Overexpression of a number of protein kinases in the rac1, dck1 and lmo1 deletion mutants indicates that Rac1, Dck1 and Lmo1 function upstream of the mitogen-activated protein kinases Cek1 and Mkc1.[ Rac1, Dck1 and Lmo1] (Mus musculus) PubMed

 6784.

These data show that in Plasmodium falciparum the mitochondrion serves as a dynamic Ca(2+) store and that PfCHA functions as a Ca(2+) efflux system expelling excess Ca(2+) from the mitochondrion.[CHA] (Mus musculus) PubMed

 6785.

The authors demonstrate that a parasite cathepsin protease, TgCPL, occupies a newly recognized vacuolar compartment (VAC) that undergoes dynamic fragmentation during Toxoplasma gondii replication.[CPL] (Mus musculus) PubMed

 6786.

The study presented here develops high-resolution genetic and physical maps in an effort to identify the XiR1 gene(s).[XiR1] (Mus musculus) PubMed

 6787.

These results demonstrate the involvement of rnjB in E. faecalis pilin gene expression and provide insight into a novel mechanism of regulation of pilus production in Gram-positive pathogens.[rnjB] (Mus musculus) PubMed

 6788.

Study conclude LukGH is a novel two-component leukotoxin with cytolytic activity toward neutrophils, and thus potentially contributes to S. aureus virulence. [LukG] (Mus musculus) PubMed

 6789.

Lipophorin (Lp) and vitellogenin (Vg), two nutrient transport proteins, reduce the parasite-killing efficiency of the antiparasitic factor TEP1.[Vitellogenin] (Mus musculus) PubMed

 6790.

It is proposed that WNV gpE can interact specifically with two cellular proteins (laminin-binding protein and alphaVbeta3 integrin) during virus entry (glycoprotein E). (Mus musculus) PubMed

 6791.

The Si influx transporter OsNIP2;1 is permeable to selenite. [NIP2;1] (Mus musculus) PubMed

 6792.

The formation of myosin filaments through the tail region has only a slight effect on binding to F-actin but has significant effects on the cortical localization of myosin II.[Myosin, Actin] (Mus musculus) PubMed

 6793.

DTH8 suppressed rice flowering under long day conditions, and plays an important role in the regulation of plant height and yield potential. [DTH8] (Mus musculus) PubMed

 6794.

The samples analyzed corresponded to SAG2 type I isolates, and they differ from classic SAG2 type I by genetic polymorphisms.[SAG2] (Mus musculus) PubMed

 6795.

Sialostatin L2 - but not sialostatin L - facilitates the growth of B. burgdorferi in murine skin. [sialostatin L2] (Mus musculus) PubMed

 6796.

Results indicate that SMAD1 signaling is active in culture as well as in blastula embryos, but STAT3 is inactive and can thus not be involved in pluripotency control of blastula cells or their derived pluripotent in vitro counterparts. (Mus musculus) PubMed

 6797.

part of Xenopus Dead end-localization elements critical for somatic RNA clearance exhibits homology to zebrafish nanos1 and appears to be targeted by Xenopus miR-18 for somatic mRNA clearance. [miR-18] (Mus musculus) PubMed

 6798.

The effects of heat stress and hypothyroidism on reproductive hormones and vasoactive intestinal polypeptide (VIP)-immunoreactive cells in the hypothalamus in hens are reported.[VIP] (Mus musculus) PubMed

 6799.

An external constant electric field is able to modify the secondary structure of a protein and induce a transition from a beta-sheet into a helix-like conformation.[gp120] (Mus musculus) PubMed

 6800.

Gene knockout studies in the bloodstream form of the parasite indicate that the neutral sphingomyelinase is essential for growth and survival.[neutral sphingomyelinase] (Mus musculus) PubMed

 6801.

CRA1 regulates lignin and flavonoid contents and, consequently, affects polar auxin transport and root growth. [CRA1] (Mus musculus) PubMed

 6802.

OmpK gene cloned/expressed; DNA/protein sequences reported; sequence alignment/phylogenetic analysis among Vibrio proteins reported. OmpK protein is likely a genus-specific antigen for Vibrio species [OmpK] (Mus musculus) PubMed

 6803.

Native Scl1 mediated group A Streptococcus adherence to ligand-coated glass cover slips and promoted GAS internalization into HEp-2 cells.[Scl1] (Mus musculus) PubMed

 6804.

The authors found that EAP and Nptase also play a role in biofilm formation under iron-replete conditions in the presence of human serum.[Eap] (Mus musculus) PubMed

 6805.

The HcpA pilin monomer of the HCP produced by EHEC O157:H7 is a potent inducer of IL-8 and TNF-alpha release [HCP] (Mus musculus) PubMed

 6806.

a stepwise mechanism for the replacement of H2A with Htz1 in SWR1 complex[SWR1][H2A.Z] (Mus musculus) PubMed

 6807.

Vpu protein does not affect the conformation of influenza A virus HA in acidic trans-Golgi compartment. [HA] (Mus musculus) PubMed

 6808.

The blocking of complement receptor 3-related protein by antibodies before adherence affected the fitness of biofilm, which was not able to revitalize in the later stages.[complement receptor 3-related protein] (Mus musculus) PubMed

 6809.

Structural and functional characterization of the ga-substituted ferredoxin from Synechocystis sp. PCC6803, a mimic of the native protein (Mus musculus) PubMed

 6810.

HHV-6 glycoprotein Q1 is an essential gene for virus growth. [gQ1] (Mus musculus) PubMed

 6811.

Age3p, a functional ortholog of GCS1, is required for hyphal growth [GCS1] (Mus musculus) PubMed

 6812.

The authors provide the first experimental evidence of the function of the Candida albicans putative gene orf19.7626 as an eIF4E protein.[eIF4E] (Mus musculus) PubMed

 6813.

These data establish a new role to EFG1 in affecting the drug susceptibilities of Candida albicans cells, independent of reactive oxygen species and known drug efflux mechanisms.[EFG1] (Mus musculus) PubMed

 6814.

Age3p, a functional ortholog of GCS1, is required for hyphal growth [AGE3] (Mus musculus) PubMed

 6815.

In Zygosaccharomyces rouxii, the loss of Fps1p compromised the use of acetamide and several other small amides as sources of nitrogen, an indication that these amides enter the cells of this yeast by passive diffusion through the Fps1p pore.[Fps1] (Mus musculus) PubMed

 6816.

identification of a specific damage-dependent Mec1/Tel1 site of Slx4 phosphorylation, Thr 113, that is required for efficient cleavage of 3' non-homologous tails by Rad1-Rad10 [Mec1; TEl1; Slx4; Rad1; Rad10] (Mus musculus) PubMed

 6817.

Loss of HNT3 in rad27Delta cells, which are deficient in long-patch base excision repair (LP-BER), resulted in synergistic sensitivity to H(2)O(2) and methylmethane sulfonate. [Rad27] (Mus musculus) PubMed

 6818.

The ceKDM7A is a histone demethylase specific for H3K9me2 and H3K27me2, and the PHD finger binding to H3K4me3 guides the demethylation activity in vivo.(ceKDM7A proteins) (Mus musculus) PubMed

 6819.

The ceKDM7A is recruited to the promoter to demethylate H3K9me2 and H3K27me2 and activate gene expression through the binding of the PHD domain to H3K4me3. (ceKDM7A protein) (Mus musculus) PubMed

 6820.

ACP adopts a unique conformation for each intermediate driven by changes in the internal fatty acid binding pocket [ACP] (Mus musculus) PubMed

 6821.

These results suggest that immediate-early protein 3 (IE3) acts as a key protein for viral DNA replication by establishing pre-replication domains via recruitment of the required viral and cellular proteins, and by reducing host defences.[IE3] (Mus musculus) PubMed

 6822.

LPD1 was required for filamentous growth under a serum-containing hyphal-inducing condition. [Lpd1] (Mus musculus) PubMed

 6823.

The isolated virus lacking an intact transcriptional activator C2 protein is the causes of the cotton leaf curl disease.[C2] (Mus musculus) PubMed

 6824.

daf-2(e1370) and daf-2(e1370);pept-1(lg601) animals were compared with a focus on genes that showed significantly higher changes in expression levels in daf-2;pept-1 than in daf-2.[pept-1] (Mus musculus) PubMed

 6825.

crystals of isopropylmalate dehydrogenase were grown in the presence of various combinations of substrate and/or cofactors[isopropylmalate dehydrogenase ] (Mus musculus) PubMed

 6826.

Analysis of the products demonstrates unambiguously that Ari1p directs hydride transfer from the si face of NADPH to the re face of furfural.[Ari1] (Mus musculus) PubMed

 6827.

FeoA is found to adopt a unique dimer cross-linked by two zinc ions and six anions (chloride ions). [ FeoA ] (Mus musculus) PubMed

 6828.

This study identifies HPA-1 and HPA-2 as novel negative regulators of EGF signaling and constitutes the first report of EGF signaling as a major pathway for healthy aging.[EGFR, PLC gamma, IP3R] (Mus musculus) PubMed

 6829.

formation of the 'glutamine transamidosome' from the bacterium Thermotoga maritima, consisting of tRNA(Gln), GluRS and the heterotrimeric amidotransferase GatCAB, and its crystal structure at 3.35 A resolution [GluRS; GatC&A&B] (Mus musculus) PubMed

 6830.

These results support a model whereby transcription factors SBF and MBF may be differentially activated by Cln3.[Cln3] (Mus musculus) PubMed

 6831.

These data indicate that HBZ of human T-cell leukemia virus type 1 activates Dkk1 expression through its interaction with p300/CBP.[HBZ] (Mus musculus) PubMed

 6832.

Cryptococcus neoformans CLN1 is able to complement Saccharomyces cerevisiae G1 cyclin deficiency, demonstrating that it is a G1 cyclin homologue.[CLN1] (Mus musculus) PubMed

 6833.

Complementation and epistasis analyses reveal that it is the repression of exsA expression, but not exsB expression, by LuxR that is responsible for the QS-mediated repression of type 3 secretion system genes at high cell density.[LuxR & ExsA] (Mus musculus) PubMed

 6834.

Sorting of transmembrane GRA6 to the host vacuole is driven by its N-terminal hydrophilic domain. [GRA6] (Mus musculus) PubMed

 6835.

These findings reveal an important role for eIF4H/drr-2 in the TOR-mediated longevity responses to dietary restriction.[Drr-2, TOR] (Mus musculus) PubMed

 6836.

HOS2 and HDA1 have opposite roles in the regulation of hyphal formation [HOS2][HDA1] (Mus musculus) PubMed

 6837.

role of PPK2 as a novel pathogenicity determinant that is critical for C. jejuni survival, adaptation, and persistence in the host environments [PPK2] (Mus musculus) PubMed

 6838.

MORN1 is required for basal complex assembly [MORN1] (Mus musculus) PubMed

 6839.

Gpa2 and Pde1 are responsible for down-regulation of cAMP signalling induced by glucose addition. [Gpa2 and Pde1] (Mus musculus) PubMed

 6840.

caspase-1 activation by SopE and the type iii secretion system-1 [SopE][T1] (Mus musculus) PubMed

 6841.

VPA0450 is an inositol polyphosphate 5-phosphatase that hydrolyzed D5 phosphate from plasma membrane phospholipid phosphatidylinositol 4,5-bisphosphate; it disrupted cytoskeletal binding sites on inner membrane surface; caused membrane blebbing[VPA0450] (Mus musculus) PubMed

 6842.

findings provide evidence that 5'-end capping is not a constitutive process that necessarily always proceeds to completion and demonstrates that Rai1 has an essential role in clearing mRNAs with aberrant 5'-end caps[Rai1] (Mus musculus) PubMed

 6843.

Our results indicate that interactions between p27 and p88 replicase proteins play an essential role in viral RNA replication and in suppressing RNA silencing via the 480-kDa replicase complex assembly.[p27, p88] (Mus musculus) PubMed

 6844.

The detection of tet(c) positive E. coli was found to be difficult using the current for tetracycline resistance.[TetC] (Mus musculus) PubMed

 6845.

These results indicate that virA plays an important role in the pathogenicity of Streptococcus suis serotype 2.[virA] (Mus musculus) PubMed

 6846.

The C-terminal part of the Nce102 protein is necessary for localization of both Nce102 itself and Can1 to membrane compartment of arginine permease Can1 and also for the formation of furrow-like membrane invaginations.[Nce102] (Mus musculus) PubMed

 6847.

The Uga3 and Uga35/Dal81 transcription factors bind to the UGA4 promoter in a gamma-aminobutyric acid-dependent manner and that this binding is impaired by the presence of leucine.[Uga3, Uga35, Uga4] (Mus musculus) PubMed

 6848.

This study demonstrates the importance of chromatin remodeling by the conserved histone acetyltransferase Gcn5 in regulating the expression of specific genes that allow C. neoformans to respond appropriately to the human host.[Gcn5] (Mus musculus) PubMed

 6849.

These results demonstrate that the endosomal sorting complex required for transport pathway has Rim101-independent functions for C. albicans virulence.[Rim101] (Mus musculus) PubMed

 6850.

These results suggest no significant role of EhROM1 in complement resistance but unexpected roles in parasite adhesion and phagocytosis.[EhROM1] (Mus musculus) PubMed

 6851.

These results indicate that the expression of AQP4 and Kir4.1 channels on Muller cells is associated with the changes in ocular volume seen during the induction of refractive errors.[Kir1.4] (Mus musculus) PubMed

 6852.

crystal structure of FucP at 3.1 A resolution, which shows that it contains an outward-open, amphipathic cavity [FucP] (Mus musculus) PubMed

 6853.

The involvement of glycoprotein G in membrane fusion is investigated through electron microscopy. (Mus musculus) PubMed

 6854.

These data suggest a putative role of DNA polymerase A in translesion DNA synthesis in Entamoeba histolytica.[DNA polymerase A] (Mus musculus) PubMed

 6855.

STEC Subtilase cytotoxin (SubAB) activates apoptotis pathways activatd by Bax/Bak.[SubAB] (Mus musculus) PubMed

 6856.

These results indicate that oxidized LolA stably binds to LolCDE, which causes strong envelope stress [LolA] (Mus musculus) PubMed

 6857.

The role of small noncoding RNAs in the translation and stability of rpoS mRNA during expression is reported [rpoS] (Mus musculus) PubMed

 6858.

These results suggest that the toxT promoter recognition function provided by ToxR can facilitate the interaction of TcpP with the toxT promoter. [TcpP; ToxT; ToxR] (Mus musculus) PubMed

 6859.

The results show that the native lipoprotein SitC-His specifically colocalizes with murine TLR2, is internalized by host cells, induces proinflammatory cytokines, and triggers intracellular accumulation of TLR2.[SitC] (Mus musculus) PubMed

 6860.

This report characterizes a a genetic locus unique to staphylococci called rsr that has a role in repressing teh virulence regulator agr.[RSR; AGR] (Mus musculus) PubMed

 6861.

The role of the SasG surface protein in bacterial adhesion and biofilm formation is reported.[SasG] (Mus musculus) PubMed

 6862.

Osmotic induction of transcription of the sigHp2 promoter that is specifically recognized by RNA polymerase containing sigma(H) was absent in an S. coelicolor bldG mutant, indicating a role of BldG in sigma(H) activation.[sigma H] (Mus musculus) PubMed

 6863.

The removal of Dig1 results in a specific increase in intrinsic and extrinsic noise in the transcriptional outputs of the mating pathway. The dig1Delta cells, Ste12 relocalizes from the nucleoplasmic distribution seen in wild-type cells. (Mus musculus) PubMed

 6864.

We report LT-IIc, a new type II heat labile enterotoxin (HLT) encoded from an enterotoxigenic E. coli (ETEC) strain isolated from an avian host. [LT-IIC] (Mus musculus) PubMed

 6865.

Gelatinase (GelE) is the principal mediator of pathogenesis in endocarditis. [GelE] (Mus musculus) PubMed

 6866.

Telomerase activity in the lens epithelial cells of posterior capsule opacification is lower than that in the equator capsule. [Telomerase] (Mus musculus) PubMed

 6867.

Mutant strains deficient in nadA, nadC, or nadS required exogenous nicotinate for growth. NdnR acts as a transcriptional repressor of NAD de novo biosynthesis genes.[nadC, nadS and NdnR] (Mus musculus) PubMed

 6868.

We report the identification and activities of three novel superantigen-encoding genes in Streptococcus equi subsp. zooepidemicus: szeF, szeN, and szeP.[szeF, szeN, szeP] (Mus musculus) PubMed

 6869.

The results indicate that the genetic blockage of starch synthesis in the sta6 and sta7-10 mutants increases the accumulation of lipids on a cellular basis during nitrogen deprivation.[sta7-10] (Mus musculus) PubMed

 6870.

open reading frame of flaC gene contains 1155 bp and the putative protein consists of 384 amino acid residues[FlaC] (Mus musculus) PubMed

 6871.

[2 genes, Coa3 & Cox14]Coa3 and Cox14 are required for Mss51 association with newly synthesized Cox1. (Mus musculus) PubMed

 6872.

We report a mechanism employed by Fusobacterium nucleatum for cell death induction of human lymphocytes via two outer membrane proteins (OMPs), Fap2 and RadD, which share regions homologous to autotransporter secretion systems.[Fap2,RadD] (Mus musculus) PubMed

 6873.

Zip1-S75 phosphorylation does not alter chromosome synapsis or double-strand break repair, indicating that Mec1 separates centromere pairing from the other functions of Zip1.[Mec1, PP4] (Mus musculus) PubMed

 6874.

These results show that recognition of C. albicans by S. gordonii involves Als3 protein-SspB protein interaction, defining a novel mechanism in fungal-bacterial communication. (Mus musculus) PubMed

 6875.

A functional analysis of two major homologues of the velvet complex in P. chrysogenum, velA (PcvelA) and PclaeA, is provided.[PcvelA, PclaeA] (Mus musculus) PubMed

 6876.

Pat1a is a translational repressor in oocytes in a CPEB-containing complex, and Pat1b is a component of P-bodies in somatic cells.[Pat1a and Pat1b] (Mus musculus) PubMed

 6877.

The colicin rRNase domain binds the A site of the decoding center in the 70S ribosome & cleaves the 16S rRNA between A1493 & G1494 via the concerted action of conserved residues Glu62 & His58 of the cytotoxic domain of colicin E3. Colicin E3. (Mus musculus) PubMed

 6878.

19-A resolution shows a dodecameric structure with a central channel having a closed periplasmic gate. The periplasmic domain forms a vestibule with a conserved constriction. It binds a pentameric exoprotein & the tip of the T2SS pseudopilus. GspD. (Mus musculus) PubMed

 6879.

The N-terminal S-layer-homologous domain of the Mep45 outer membrane protein was found to be protruding into the periplasmic space and was responsible for binding to peptidoglycan.[Mep45] (Mus musculus) PubMed

 6880.

show that the yeast Acr3p mediates not only high-level resistance to arsenite but also moderate tolerance to antimonite[Acr3p] (Mus musculus) PubMed

 6881.

Compartmentalization of NS1 within the cell contributes to the pathogenicity of avian influenza virus H7N1. [NS1] (Mus musculus) PubMed

 6882.

In contrast to other characterized N1 neuraminidases, which are all members of group 1, 2009 H1N1 neuraminidase does not have a 150-cavity. (Mus musculus) PubMed

 6883.

can be taken to imply that the TrwB transmembrane domain plays a regulatory role in its biological activity[TrwB] (Mus musculus) PubMed

 6884.

Bovine foamy virus transactivator BTas interacts with cellular RelB to enhance viral transcription. [BTas] (Mus musculus) PubMed

 6885.

findings show that GtrA, specifically binds the promoter of the matPQMAB operon, positively regulating its expression [GtrA] (Mus musculus) PubMed

 6886.

Data show that chloramphenicol boiosynthetsis is catalyzed by the enzyme CmlA from an operon containing the genes for biosynthesis of L-PAPA and the nonribosomal peptide synthetase CmlP: [CmlA and CmlP] (Mus musculus) PubMed

 6887.

Dom34 & GTP bind to Hbs1 with strong cooperativity. Dom34 acts as GTP-dissociation inhibitor. Conformational change in Dom34 occurs upon binding to Hbs1. Dom34-Hbs1 complex terminates translation & commits mRNAs to no-go decay.[Dom34, Hbs1] (Mus musculus) PubMed

 6888.

Data identified the transcription factor Meis2 as one of the main targets of miR-204 function: [miR-204 and Meis2] (Mus musculus) PubMed

 6889.

Injection of peptidoglycan-polysaccharide resulted in fever, increased concentrations of haptoglobin on the day of and the day after challenge, and decreased concentrations of progesterone on days 14 and 21.(haptoglobin, HP) (Mus musculus) PubMed

 6890.

A direct relationship between ecto-ATPase activity and adhesion to host cells was observed. In these assays, inhibition of enzyme activity resulted in decreased levels of yeast adhesion to epithelial cells.[ecto-ATPase] (Mus musculus) PubMed

 6891.

A new member of the Bombyx mori small heat shock protein family, BmHSP25.4 was cloned and characterized.[BmHSP25.4] (Mus musculus) PubMed

 6892.

An E(z) homolog, EZH, in the green alga Chlamydomonas reinhardtii, was characterized to gain insight on the role of PRC2 in single celled organisms.[PRC2, EZH] (Mus musculus) PubMed

 6893.

Both LIS-1 and the dynein heavy-chain DHC-1 are required for integrity of the actin cytoskeleton in C. elegans.[DHC-1] (Mus musculus) PubMed

 6894.

BTEB1 activated the FGFR1 promoter via interaction with the Sp1-like binding site located at -59 bp within the FGFR1 promoter.[BTEB1] (Mus musculus) PubMed

 6895.

Gain-of-function mutations in CgPDR1 contributed to the clinical azole resistance, but different mutations had various degrees of impact on the CgPDR1 target genes. [PDR1] (Mus musculus) PubMed

 6896.

The observed post-translational mannosylation of polar tube protein PTP1 may be involved in the functional properties of the polar tube, including its adherence to host cells during penetration. [PTP1] (Mus musculus) PubMed

 6897.

results suggest that Clp upregulates the gum operon by binding to two non-consensus sites [Clp] (Mus musculus) PubMed

 6898.

SRS3 is a putative kinesin 13 protein. [SRS3] (Mus musculus) PubMed

 6899.

These data support the critical role of residue 87 in the stability and folding of VIM-2. [VIM-2] (Mus musculus) PubMed

 6900.

Our data show that BpeAB-OprB of Burkholderia pseudomallei 1026b is a multidrug efflux system which extrudes macrolides, fluoroquinolones, tetracyclines, acriflavine, and, to a lesser extent, chloramphenicol. [BpeA, BpeB, OprB] (Mus musculus) PubMed

 6901.

The authors propose that the reduced virulence of the pga29 mutant is a consequence of altered surface properties, resulting in altered fungal recognition. (Mus musculus) PubMed

 6902.

The authors used indirect immunofluorescence assays and immunoelectron microscopy to demonstrate that PfASP is localized in the neck of rhoptries and not in micronemes as previously described.[ASP] (Mus musculus) PubMed

 6903.

Based on these results, Theileria parva SCOP likely plays an important role in NF-kappaB activation and apoptosis inhibition during Theileria infection.[SCOP] (Mus musculus) PubMed

 6904.

These results show that bovine LEE-negative STEC strains possessed genes encoding virulence factors present in human LEE-negative STEC strains that are associated with disease. (Mus musculus) PubMed

 6905.

The authors show that short N-terminal fragments (</=70 amino acids) from SepL are capable of targeting fusion proteins for secretion and translocation. (Mus musculus) PubMed

 6906.

Results point to considerable potential for a role for FKBP16-1 in early chloroplast development, architecture of photosynthetic apparatus and plant development: [FKBP16-1] (Mus musculus) PubMed

 6907.

TbRGG2 facilitates complete utilization of certain gRNAs.[RGG2] (Mus musculus) PubMed

 6908.

Pichia pastoris mutant strains, defective in the enzyme pyruvate carboxylase, showed a pronounced growth defect on d-alanine, concomitant with a significant reduction in Dao1p activity relative to the wild-type control.[pyruvate carboxylase & Dao1] (Mus musculus) PubMed

 6909.

Collectively, these results indicate that SarA binds directly to the tst promoter and that SarA plays a significant and direct role in the expression of tst.[SarA & tst] (Mus musculus) PubMed

 6910.

Here, the authors evidence that K-bZIP affects IFN signaling, resulting in impaired IFN-stimulated genes expression.[K-bZIP] (Mus musculus) PubMed

 6911.

Cadmium and phytochelatin levels were determined in protoplasts and vacuoles isolated from leaves of Nicotiana tabacum expressing either of two phytochelatin synthase genes, AtPCS1 and CePCS.[CePCS] (Mus musculus) PubMed

 6912.

subtle differences between the TDO and IDO reactions [TDO] (Mus musculus) PubMed

 6913.

The azole susceptibilities of the C. albicans isolates correlated well with ERG11 mutations. [ERG11] (Mus musculus) PubMed

 6914.

The presence of 2 DNNND repeats in microsatellite ms4760 of pfnhe, a sodium hydrogen exchanger, was associated with reduced susceptibility to quinine, while 3 repeats were associated with restoration of susceptibility. [pfnhe] (Mus musculus) PubMed

 6915.

Rabbit antithymocyte globulin alters the balance of regulatory to memory effector T cells posttransplant, providing an explanation for how it positively impacts transplant outcome. (antithymocyte globulin) (Mus musculus) PubMed

 6916.

There is gain of function, i.e., multiple embryos in the seeds in the knockout mutant OsPE whereas its wild-type allele strictly controls single embryo per seed.[OsPE] (Mus musculus) PubMed

 6917.

Polymorphism of host MMP-3, but noth dupA of Helicobacter pylori, correlate with the susceptibility to duodenal ulcer. [dupA] (Mus musculus) PubMed

 6918.

CD1d is downregulated by the HPV16 E5 and HPV6 E5 protein. [E5] (Mus musculus) PubMed

 6919.

AatA increased adherence of non-fimbriated E. coli K-12 strain to a chicken fibroblast cell line. [aatA] (Mus musculus) PubMed

 6920.

VP23R mediates formation of virus-mock basement membrane to provide attaching sites for lymphatic endothelial cells. [VP23R] (Mus musculus) PubMed

 6921.

Blue copper-binding protein, heat-stress transcription factor, WIR1A protein and ent-kaurene synthase transcripts were significantly involved in the resistance phenotype across all genotypes.[heat-stress transcription factor, WIR1A, ent-kaurene synthase] (Mus musculus) PubMed

 6922.

These results show that over-expression of ZmPP2C2 in tobacco enhanced tolerance to cold stress, suggesting that this new gene, ZmPP2C2, may act as a positive regulator of cold resistance in plants.[PP2C2] (Mus musculus) PubMed

 6923.

Presence of the IS1016-bexA deletion is associated with enhanced virulence in non-type b H. influenzae.[bexA] (Mus musculus) PubMed

 6924.

The knockout mutant OsAPC6 interferes with the gibberellic acid signaling pathway leading to reduced height and cell size probably through ubiquitin-mediated proteolysis.[APC6] (Mus musculus) PubMed

 6925.

PLD activity was able to hydrolyze a fluorescently labeled analog of phosphatidylcholine and was capable of performing the transphosphatidylation reaction characteristic of PLDs.[PLD] (Mus musculus) PubMed

 6926.

In addition to its antifungal activity, AcAMP is the first fungal peptide exhibiting antibacterial activity against several Gram-positive and Gram-negative bacteria.[AcAMP] (Mus musculus) PubMed

 6927.

Two dnai2 genes function either redundantly or distinctly in tissues possessing motile cilia.[jaodori] (Mus musculus) PubMed

 6928.

The combined results suggest that 3C-mediated cleavage of PTB might be involved in down-regulation of viral translation to give way to subsequent viral genome replication.[3C] (Mus musculus) PubMed

 6929.

The zinc site and protein structure in dimeric HypA are dependent on both the nickel binding status and the pH.[HypA] (Mus musculus) PubMed

 6930.

structure of DspF, required for virulence of Erwinia amylovora, was modeled; study supports the significance of the predicted beta-sheet helix-binding groove in DspF chaperone function [DspF] (Mus musculus) PubMed

 6931.

the reduced flavin mononucleotide coenzyme of IDI-2 functions as an acid/base catalyst [IDI-2] (Mus musculus) PubMed

 6932.

Sialic acid transport and catabolism are cooperatively regulated by SiaR and CRP. [SiaR and CRP] (Mus musculus) PubMed

 6933.

Gup1p strongly interferes with the capacity of cells to develop hyphae, to adhere, to invade, and to form biofilm. (Mus musculus) PubMed

 6934.

Data determine the structures of the FK506 binding domain of Plasmodium vivax FKBP35 in unliganded form by NMR spectroscopy and in complex with FK506 by X-ray crystallography [FKBP35]. (Mus musculus) PubMed

 6935.

Four new members of the SOCS family of molecules in rainbow trout (Oncorhynchus mykiss), CISH and SOCS6, 7 and 9, are described for the first time in this species[socs9] (Mus musculus) PubMed

 6936.

PLB activity is involved in the process of adhesion, internalization and subsequent down-regulation of macrophage activation. [PLB] (Mus musculus) PubMed

 6937.

LHbeta and LH-R mRNA expression might be involved in initial maturation events of gametes, at least in males [LHbeta] (Mus musculus) PubMed

 6938.

Myo2p transport along actin cables may support a feedback loop by which delivery of astral microtubule plus ends sustains Kar9p polarized recruitment to the bud-ward spindle pole. [Kar9] (Mus musculus) PubMed

 6939.

rabB Delta and rabA Delta mutations are synthetically lethal, demonstrating that Rab5-mediated establishment of endosomal identity is essential for A. nidulans.[RabB, rab5] (Mus musculus) PubMed

 6940.

IFT70/CrDYF-1 is a canonical subunit of intraflagellar transport (IFT) particle complex B and strongly support the hypothesis that the IFT machinery has species- and tissue-specific variations with functional ramifications.[IFT70] (Mus musculus) PubMed

 6941.

PotD plays a physiological role in the uptake of polyamines in vivo. [PotD] (Mus musculus) PubMed

 6942.

To provide structural insights into how BoNT/D enters neuronal cells, the crystal structure of the receptor binding domain (S863-E1276) for this serotype (BoNT/D-HCR) was determined at 1.65A resolution.[BoNT/D] (Mus musculus) PubMed

 6943.

The expression profiles of the MtTFIIS-like gene were compared to those of the MtTFIIS gene, encoding the canonical TFIIS protein, which was similarly up-regulated in response to both stresses; copper and polyethylene glycol.[TFIIS} (Mus musculus) PubMed

 6944.

czrC is encoding zinc and cadmium resistance in CC398 MRSA isolates, and that it is widespread both in humans and animals. [czrC] (Mus musculus) PubMed

 6945.

ScanProsite analysis of IAP4 amino acid sequence show that it contains a baculovirus Inhibitor of Apoptosis repeat (BIR) motif at the N-terminal portion from 18 to 61 amino acid and a Zinc finger RING motif near its C-terminus.[IAP4] (Mus musculus) PubMed

 6946.

a novel transcriptional regulator that binds to the promoter region of succinyl-CoA synthetase (sucCD) in Corynebacterium glutamicum was identified. [SucR] (Mus musculus) PubMed

 6947.

The structure of G-actin is presented in a form that is devoid of polymerization-deterring chemical modifications or binding partners, either of which may alter its conformation.[G-actin] (Mus musculus) PubMed

 6948.

Coronin and Aip1 are important effectors that act together in maintaining the balance of actin polymerization and depolymerization in living cells.[Coronin and Aip1] (Mus musculus) PubMed

 6949.

structural, dynamical, and thermodynamic properties of a model potassium channel [KcsA] (Mus musculus) PubMed

 6950.

kaposin-B plays a key role in PROX1 upregulation during lymphatic reprogramming of blood vascular endothelial cells by KSHV (Mus musculus) PubMed

 6951.

Rbf1 is a novel master regulator in a multilayered network of transcription factors that facilitates the complex regulatory traits of sexual and pathogenic development of Ustilago maydis (Mus musculus) PubMed

 6952.

These findings provide direct genetic evidence that CTCF functions as a chromatin insulator that prevents the promiscuous transcription of surrounding genes and blocks the epigenetic silencing of an essential promoter, Qp, during EBV latent infection (Mus musculus) PubMed

 6953.

vaccinia virus complement control protein domains 2 and 3 provide binding surface for factor I interaction, whereas domain 1 mediates dissociation of C2a and Bb from the classical and alternative pathway C3 convertases, respectively. (Mus musculus) PubMed

 6954.

the mechanism for Ca2+-dependent CPI-17 phosphorylation and its effect of G protein activation is investigated. (Mus musculus) PubMed

 6955.

a novel chromatin factor, X non-disjunction factor 1 (xnd-1), is responsible for the global distribution of meiotic crossovers in C. elegans [xnd-1] (Mus musculus) PubMed

 6956.

the exchange coupling constant in the type 3 center in a fully metalated oxidase [Fet3] (Mus musculus) PubMed

 6957.

Gcn5 impacts genome integrity via multiple mechanisms, including nucleosome assembly.[Gcn5] (Mus musculus) PubMed

 6958.

Localization of Sst2 to the projection prevents excess G-protein activation during the pheromone response.[Sst2] (Mus musculus) PubMed

 6959.

The structure-function relationship of cohesin, an essential chromosome maintenance protein, is investigated by analyzing its collective dynamics and conformational flexibility.[cohesin] (Mus musculus) PubMed

 6960.

Transcription elongation by bacteriophage T7 RNAP was quatified on small, circular DNA templates approximately 100 bp in size.[RNAP] (Mus musculus) PubMed

 6961.

findings suggest that tricarboxylic acid cycle enzymes AcnA and SdhA were not controlled by RyhB; study provides evidence to delineate the unique RhyB gene regulation in S. oneidensis [RyhB] (Mus musculus) PubMed

 6962.

An ecdysone receptor and Broad-Complex Z2 (BR-Z2) are required for maximal BMWCP10 expression in the wing disc of Bombyx mori. [BMWCP10] (Mus musculus) PubMed

 6963.

Clb2-Cdk1 protects Swe1 from premature degradation until its Hsl1 mediated de-protection, which enables its Cdc5 mediated degradation.[Clb2, Cdh1, Swe1] (Mus musculus) PubMed

 6964.

FXDY-11 associates with and may regulate Na+-K+-ATPase activity in the gill of Atlantic salmon. (Mus musculus) PubMed

 6965.

HPP1 represents a novel type of peptide pheromone precursors, and is essential for male fertility. [HPP1] (Mus musculus) PubMed

 6966.

Thoracic gunshot injury decreased Cx40 level and increased pulmonary vascular permeability, with a significant correlation between Cx40 staining intensity and vascular permeability. [Connexin 40] (Mus musculus) PubMed

 6967.

The heterodimeric glycoprotein GP3 is a constituent of the insoluble extracellular matrix. The backbones of both GP3 subunits are encoded by the same gene. [GP3] (Mus musculus) PubMed

 6968.

crystal structure of EF-Tu and aminoacyl-tRNA bound to the ribosome with a GTP analog, to 3.2 angstrom resolution; activated conformation is due to interaction of the catalytic histidine with A2662 of the sarcin-ricin loop of the 23S ribosomal RNA [EF-TU] (Mus musculus) PubMed

 6969.

X-ray structure of the MATE transporter NorM from Vibrio cholerae determined to 3.65 A[NorM] (Mus musculus) PubMed

 6970.

These results suggest that Sin catalytic activity and oligomerization state are tightly linked.[Sin] (Mus musculus) PubMed

 6971.

The protein kinase Elm1 is an obligate regulator of the pindle position checkpoint, and this function requires localization of Elm1 to the bud neck. [ELM1 protein, S cerevisiae] (Mus musculus) PubMed

 6972.

These data suggest that Toxoplasma gondii cyclophilin 18 recruits cells and enhances the growth of host cells at the site of infection for maintenance of the interaction between the parasite and host.[cyclophilin 18] (Mus musculus) PubMed

 6973.

OsNSP1 and OsNSP2 fully restore the defects in root nodulation symbiosis of Lotus japonicus mutants. [OsNSP2] (Mus musculus) PubMed

 6974.

OsNPR1 has a role in the reallocation of energy and resources during defense responses. (Mus musculus) PubMed

 6975.

Mss116 stimulates group II intron folding through a multi-step process that involves electrostatic stabilization of early intermediates and ATP hydrolysis during the final stages of native state assembly [Mss116] (Mus musculus) PubMed

 6976.

Data show that the mutant ferric-binding protein A (FbpA) isolated from H. influenzae strain DL63, retain significant iron-binding affinity regardless of the nature of the replacement amino acid: [FbpA] (Mus musculus) PubMed

 6977.

Loss of OsJAG function results in maldevelopment of all floral organs, such as degenerated lemma and palea, elongated lodicules and deformed and sterile pistil. (Mus musculus) PubMed

 6978.

These data support that Trypanosoma cruzi protein kinase A phosphorylates trans-sialidase super family members in vivo.[protein kinase A] (Mus musculus) PubMed

 6979.

The plenty mutant exhibited a unique phenotype of moderate hypernodulation. [PLENTY] (Mus musculus) PubMed

 6980.

expression of both trout (t) FoxP3a and tFoxP3b are detectable in all the 14 tissues examined without any significant difference except in muscle in which the expression of tFoxP3a was higher[ FoxP3a and FoxP3b ] (Mus musculus) PubMed

 6981.

Abnormal accumulation of proglutelin in the esp2 mutant is caused by the deficiency of PDIL1-1. PDIL1-1 disrupts the accumulation and packaging of rice seed storage proteins. [PDIL1-1] (Mus musculus) PubMed

 6982.

FbsB(C) was cloned, expressed and purified. Dot blot, Western blot and ELISA experiments carried out with the purified protein showed that FbsB C-terminal, FbsB(C) has the ability to bind to bovine fibrinogen.[FsbB] (Mus musculus) PubMed

 6983.

Identified is a PWL2 allele gene, which was termed PWL2D, in a strain of M. grisea. [PWL2] (Mus musculus) PubMed

 6984.

Data describe the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by structural and functional analysis of the U597C mutant. (Mus musculus) PubMed

 6985.

OsDSG1 encodes a RING finger E3 ligase that negatively regulates OsABI3. [OsDSG1] (Mus musculus) PubMed

 6986.

MtATB2 is a bZIP transcription factor regulated by sucrose and localized to vascular tissues and root and nodule apices. [ATB2] (Mus musculus) PubMed

 6987.

These results suggest that plasma membrane sphingomyelin is required for targeting of Helicobacter pylori VacA to membrane rafts important for subsequent Cdc42-dependent pinocytic cellular entry.[VacA] (Mus musculus) PubMed

 6988.

study describes the purification and antibacterial spectrum of E229DL, a cationic and highly hydrophobic member of the delta-lysin peptide family that exhibits relatively little hemolytic activity [E229DL] (Mus musculus) PubMed

 6989.

expression diversity of the TaLTP genes [TaLTP] (Mus musculus) PubMed

 6990.

PfRh2a functions in sialic acid-independent invasion of erythrocytes. [PfRh2a] (Mus musculus) PubMed

 6991.

Hap2 is required for prf1 gene expression. [prf1] (Mus musculus) PubMed

 6992.

TaCHP enhances stress tolerance via the promotion of CBF3 and DREB2A expression.[TaCHP] (Mus musculus) PubMed

 6993.

This study showed that beta2-Adrenergic receptors and G-protein-coupled receptor kinase 2 in rabbit pleural mesothelium. (Mus musculus) PubMed

 6994.

MpdA was expressed in both sporulating and nonsporulating mycelia, while mtdA was expressed only in sporulating mycelium. [Mpd, Mtd] (Mus musculus) PubMed

 6995.

RNG1 is a small, low-complexity, detergent-insoluble protein that assembles at the apical polar ring very late in the process of daughter parasite replication[RNG1] (Mus musculus) PubMed

 6996.

Differential filamentation is governed by of UME6 expression. [UME6] (Mus musculus) PubMed

 6997.

Ancestral roles for Wnt9s in early patterning of neural/oral-pharyngeal ectoderm and mesendoderm derivatives.[Wnt9a protein, zebrafish] (Mus musculus) PubMed

 6998.

The CPAF signal peptide-directed translocation of PhoA requires the Sec-dependent pathway. [CPAF] (Mus musculus) PubMed

 6999.

From these results the authors propose that FliL could participate in the coupling of MotB with the flagellar rotor in an indirect fashion.[FliL] (Mus musculus) PubMed

 7000.

A combination of proteomics and transcriptomics analyses revealed three wheat glycosyltransferase proteins as promising candidates involved in Glucuronoarabinoxylans synthesis in wheat. [TaGT43-4, TaGT47-13, and TaGT75-4] (Mus musculus) PubMed

 7001.

Rcm-1(NCU06842), rco-1(NCU06205) and ham-5(NCU11925) were required for hyphal fusion. [ram-5 (NCU11925)] (Mus musculus) PubMed

 7002.

MopB mutant showed reduced adhesion, motility and pathogenesis. [MopB] (Mus musculus) PubMed

 7003.

Interaction of Rickettsia felis OmpB with Ixodes histone H2B facilitates the infection.[H2B] (Mus musculus) PubMed

 7004.

The disruption of hpdR led to reduced production of calcium-dependent antibiotic.[hpdR] (Mus musculus) PubMed

 7005.

PilA pilus of two Enterococcus faecium isolats eassembles at different temperatures. [PilA] (Mus musculus) PubMed

 7006.

single nucleotide polymorphism in the erythrocyte binding-like 1 (ebl-1) gene [ebl-1] (Mus musculus) PubMed

 7007.

A cis-acting mutation and duplication of the Cyp9m10 gene is associated with overexpression in pyrethroid resistant Culex quinquefasciatus. (Mus musculus) PubMed

 7008.

CaGPI19 is required for normal morphology and cell wall architecture. [CaGPI19] (Mus musculus) PubMed

 7009.

The formation of a complex between the denatured monomeric form of Phb and the dissociated forms of GroEL is detected during heating at 46 degrees C.[GroEL] (Mus musculus) PubMed

 7010.

[Elongation Factor G; EF-G] crystal structure of apo EF-G at 1.9 A resolution; comparison to previously published crystal structure of Thermus thermophilus EF-G (Mus musculus) PubMed

 7011.

PDF-1 and PDF-2 are peptide deformylase homologues. PDF-1 has some different enzymic properties compared with PDF from S. aureus. PDF-2 has no peptide deformylase activity. [PDF-1; PDF-2] (Mus musculus) PubMed

 7012.

The crystal structures of a type 2 RNase H in complex with substrates containing a (5')RNA-DNA(3') junction, is reported.[RNase H2] (Mus musculus) PubMed

 7013.

Cj1514 has a specific role in the biogenesis of formate dehydrogenase, but is not required for TMAO reductase activity. [Cj1514] (Mus musculus) PubMed

 7014.

Dictyostelium requires PS for phagocytosis and cell-fate specification in a cell-autonomous manner, and show that regulation of phagocytosis requires an active gamma-secretase.[Presenilin, gamma secretase] (Mus musculus) PubMed

 7015.

These data suggest that OsC6 plays a crucial role in the development of lipidic orbicules and pollen exine during anther development in rice.[OsC6] (Mus musculus) PubMed

 7016.

Ume6 directs hyphal growth via a pathway involving Hgc1 protein. [Ume6, Hgc1] (Mus musculus) PubMed

 7017.

Upc2 protein binds to two cis-acting elements in the promoter region and autoregulated the transcription of UPC2 gene. [UPC2] (Mus musculus) PubMed

 7018.

This method may also discriminate trans-sialidase and trans-sialylation activities by running the assay in the absence of benzyl beta-d-Fuc-(1-->6)-alpha-d-GlcNAc. (Mus musculus) PubMed

 7019.

[RrgA] two variants suggest that proper folding and structural arrangement are crucial to retain functionality and are cross-reactive and cross-protective (Mus musculus) PubMed

 7020.

a role of Avt5p in cellular uptake of toxic Li+ [Avt5p] (Mus musculus) PubMed

 7021.

Rad9 phosphorylation by DDK releases Rad9 from DNA damage sites to facilitate DNA repair.[Rad9, DDK] (Mus musculus) PubMed

 7022.

an extracellular carbohydrate esterase (CcEst1) was cloned from the basidiomycete Coprinopsis cinerea [CcEst1] (Mus musculus) PubMed

 7023.

The let-7 represses expression of regeneration-associated genes such as, ascl1a and lin-28 exhibit basal expression in the uninjured retina and let-7 may inhibit this expression to prevent premature Muller glia dedifferentiation.[let7 microRNA] (Mus musculus) PubMed

 7024.

rbm-28 genetically interacts with the lin-4 developmental timing pathway and uncover a previously unrecognized role for lin-14 and lin-28 in coordinating organismal growth (Mus musculus) PubMed

 7025.

miR-1 was found to be involved in the regulation of the chondrocytic phenotype and thus to play an important role in chondrocytes during the late stage of the differentiation process, maintaining the integrity of the cartilage tissue. [mir-1] (Mus musculus) PubMed

 7026.

CagA suppresses pinocytic endocytosis and the cytotoxicity of VacA in gastric epithelial cells without affecting clathrin-dependent endocytosis.[CagA, VacA] (Mus musculus) PubMed

 7027.

a quantitative measure of how a conformational equilibrium in BtuB is modified in the crystal environment [BtiB] (Mus musculus) PubMed

 7028.

The RecA-induced deformation and the binding energetics are fine-tuned to ensure optimal sequence detection.[RecA] (Mus musculus) PubMed

 7029.

thermodynamic parameters for binding of N-acetylglucosamine oligomers to ChiB of Serratia marcescens [ChiB] (Mus musculus) PubMed

 7030.

IIA(Glc) of the sugar phosphotransferase system regulates the peptidase activity of a mammalian insulysin homolog in V. vulnificus.[IIA Glc] (Mus musculus) PubMed

 7031.

This study emphasizes the importance of core genome-encoded toxins in community acquired staphylococcal skin infections caused by the methicillin resistant USA300 strain.[alpha toxin, delta toxin] (Mus musculus) PubMed

 7032.

alpha-solenoid structures such as importin-beta may bridge the molecular gap between completely structured and intrinsically disordered proteins [Kap95p] (Mus musculus) PubMed

 7033.

Rok1 protein level is regulated by pstream open reading frames [ROK1] (Mus musculus) PubMed

 7034.

Mrc1 facilitates Mec1 phosphorylation of the S/T-Q motifs of chromatin-bound Mcm2-7 during S phase to activate replication.[Mec1, Mcm2, Mcm7, Cdc7] (Mus musculus) PubMed

 7035.

Mutations that disrupt ubiquitin binding abrogate Doa1 function, demonstrating the importance of the interaction with ubiquitin.[Doa1] (Mus musculus) PubMed

 7036.

Psh1 functions to prevent the mislocalization of Cse4.[Psh1, Cse4] (Mus musculus) PubMed

 7037.

The Cse4 centromere targeting domain is a key regulator of its stability and helps Psh1 discriminate Cse4 from histone H3.[Psh1, Cse4] (Mus musculus) PubMed

 7038.

Model for translocation and unwinding activities of NS3 helicase. The model predicts that the NS3 helicase actively unwinds duplex by reducing more than 50% the free energy that stabilizes base pairing/stacking.(NS3 helicase) (Mus musculus) PubMed

 7039.

M2 functionally reconstituted in liposomes populates at least three different conformational states over a physiologically relevant pH range, with transition midpoints that are consistent with previously reported His37 pK(a) values[M2 protein] (Mus musculus) PubMed

 7040.

The obtained results showed that PRRSV nsp1 could inhibit Poly(I:C)-induced IFN-beta promoter activity in MARC-145 cells by down-regulating the protein level of IRF-3 and inhibiting the phosphorylation of IRF-3.[nsp1] (Mus musculus) PubMed

 7041.

Helix-turn-helix motifs and a flexible sequence of Rns are required for maximal activation of fimbrial gene expression. [Rns] (Mus musculus) PubMed

 7042.

structural characterization of oxidation intermediates for AlkB demethylase [AlkB] (Mus musculus) PubMed

 7043.

A conserved X-shaped crystallographic dimer stabilized by intermolecular interactions between the second PASTA subunits of each monomer is observed in the two crystal forms of Stk1.[Stk1] (Mus musculus) PubMed

 7044.

The structures reveal an anchor-shaped substrate-binding cavity comprising a conserved hydrophobic box that clamps the nucleotide base, a buried phosphoryl binding site, and three solvent-filled pockets.[e (P4) phosphatase] (Mus musculus) PubMed

 7045.

CYP93G2 as the first enzyme that channels flavanones to C-glycosylflavone biosynthesis in rice.[CYP93G2] (Mus musculus) PubMed

 7046.

Isolated/purified apolipoprotein C-I from rainbow trout seminal plasma. (Mus musculus) PubMed

 7047.

These studies reveal that Mxr1p specifically binds to promoter regions containing multiple 5'-CYCC-3' sequences, although all DNA sequences containing the 5'-CYCC-3' motif do not qualify as Mxr1p-binding sites.[Mxr1p] (Mus musculus) PubMed

 7048.

the structure of the PcyA V225D-biliverdin IXalpha complex was determined to reveal that an unpredictable structural change occurred in the substrate-binding pocket as a result of only one mutation in a residue distant from the processing sites. [PcyA] (Mus musculus) PubMed

 7049.

The Staphylococcus aureus autoinducer-2 (AI-2) producer protein LuxS is phosphorylated by the Ser/Thr kinase Stk1 at a unique position, Thr14, abrogating its enzymatic activity.[LuxS & Stk1] (Mus musculus) PubMed

 7050.

Fim1p has a novel role as a positive actin-binding "selector" protein that promotes the access of other proteins to actin filaments by inhibiting Cdc8p. [2 genes, Fim1 and Cdc8] (Mus musculus) PubMed

 7051.

The asymmetric CEH-36 expression promotes asymmetric ngn-1 and hlh-2 expression, which in turn induces asymmetric MI neurogenesis.[CEH-36, NGN-1, HLH-2] (Mus musculus) PubMed

 7052.

study of the avian MYB/gga-miR-150 interaction shows a conservation of miR-150 target site functionality between chicken and zebrafish that does not extend to mammals [miR-150] (Mus musculus) PubMed

 7053.

Missense mutations A184V, T265M, R275Q, and N276D, which are known to occur in TEM extended-spectrum beta-lactamases from clinical isolates, were identified as suppressors of TEM-1 protein stability defects.[TEM-1 beta-lactamase] (Mus musculus) PubMed

 7054.

The assembly of the RFC.PCNA.DNA complex and its progression to holoenzyme upon addition of polymerase delta, was examined.[PCNA, RFC] (Mus musculus) PubMed

 7055.

Ubiquitin signaling in Met4 is controlled by its tandem ubiquitin-binding domain regions.[Met4] (Mus musculus) PubMed

 7056.

Residue 221 of NS1 was identified to be a new key residue involved in the C-terminal nuclear localization signal (NLS) and nucleolar localization signal (NoLS) of NS1 from A/Sydney/5/97.[NS1] (Mus musculus) PubMed

 7057.

The authors showed, in vitro, a direct interaction between Orf virus anaphase promoting complex regulator and APC2 and its interference with interactions between APC11 and APC2.[anaphase promoting complex regulator] (Mus musculus) PubMed

 7058.

the potential KLV-HAR1 receptor complex regulates symbiotic nodule development and that KLV is also a key component in other signal transduction pathways that mediate non-symbiotic shoot development [klavier] (Mus musculus) PubMed

 7059.

These findings not only provide a structural basis for the catalytic machinery of CUS but also suggest further strategies toward expanding the biosynthetic repertoire of the type III polyketide synthase enzymes.[Curcuminoid synthase] (Mus musculus) PubMed

 7060.

This study demonstrates that the PfEMP1 semi-conserved head structure is under selection for protein transport, in addition to its known roles in adhesion.[PfEMP1] (Mus musculus) PubMed

 7061.

break-induced Rad3 and Ddb1-Cul4(Cdt)(2) ubiquitin ligase-dependent Spd1 degradation and RNR activation promotes postsynaptic ssDNA gap filling during HR repair [Rad3, Ddb1, Cul4(Cdt)(2); no strain listed] (Mus musculus) PubMed

 7062.

[PbHad32p] - plays an important role in adherence to host cells and influences pathogenicity (Mus musculus) PubMed

 7063.

a negative feedback mechanism by which intracellular cAMP synthesis is inhibited by PKA through Cdc25p phosphorylation [Cdc25p] (Mus musculus) PubMed

 7064.

Orexin A was found in the beta cells of cattle, sheep, and swine where it may be implicated in the control of pancreatic activity.[orexin A] (Mus musculus) PubMed

 7065.

Overexpression of mir-57 causes dramatic posterior defects, which also mimic the phenotypes of mutant alleles of a posterior Hox gene, nob-1.[mir-57, Nob-1] (Mus musculus) PubMed

 7066.

The study describes the structure of Escherichia coli rhomboid GlpG covalently bound to a mechanism-based isocoumarin inhibitor. [GlpG] (Mus musculus) PubMed

 7067.

LytM deletion mutant lysed at a significantly faster rate compared with the wild-type. [LytM] (Mus musculus) PubMed

 7068.

We report that through binding with the human nuclear receptor importin alpha5 (Impalpha5), the viral NP is no longer oligomeric but maintained as a monomer inside the complex. (Mus musculus) PubMed

 7069.

These results suggest FliO maintains FliP stability through transmembrane domain interaction.[FliO, FliP] (Mus musculus) PubMed

 7070.

These results reveal a novel mechanism for the control of the abscisic acid/gibberellic acid balance in rice which is regulated by OsAP2-39 that in turn regulates plant growth and seed production.[OsAP2-39] (Mus musculus) PubMed

 7071.

Als5p nanodomains result from protein redistribution triggered by force-induced conformational changes in the initially probed proteins, rather than from nonspecific cell-wall perturbations.[Als5p] (Mus musculus) PubMed

 7072.

BKIP-1 is a novel auxiliary subunit critical to SLO-1 function in vivo. (Mus musculus) PubMed

 7073.

Yeast seipin is in a large discrete protein complex and plays at least a structural role in organizing droplets or in communication between droplets and ER Seipin protein, strain BY4742] (Mus musculus) PubMed

 7074.

influence of ATPgammaS on the competitive binding of RecA and single-stranded binding protein (SSB) on single-stranded DNA [RecA] (Mus musculus) PubMed

 7075.

dcaf26 was required for all of the DNA methylation.[DCAF26] (Mus musculus) PubMed

 7076.

MoCel6A showed higher hydrolytic activities on phosphoric acid-swollen cellulose (PSC), beta-glucan, and cellooligosaccharide derivatives than on cellulose, of which the best substrates were cellooligosaccharides.[MoCel6A] (Mus musculus) PubMed

 7077.

The extended signal peptide region is not essential for the secretion or the function of Pet. [Pet] (Mus musculus) PubMed

 7078.

Rice Starch Regulator1 is an AP2/EREBP family transcription factor that negatively regulates starch biosynthesis and is important for starch content and structure. [RSR1] (Mus musculus) PubMed

 7079.

Delta(6) desaturase involved in insect mate communication. [Delta 6 desaturase] (Mus musculus) PubMed

 7080.

Overexpression of the ERF1-1 B-3 ethylene response factor quantitatively increases resistance to Rhizoctonia and Phytophthora but not root knot nematode. (Mus musculus) PubMed

 7081.

Those who reported midlife physical activity, but were APOE 4 carriers, did not have reduced risk for dementia. (APOE 4] (Mus musculus) PubMed

 7082.

Single-stranded DNA binding protein is targeted to the apicoplast and it binds to apicoplast DNA (Single-stranded DNA binding protein). (Mus musculus) PubMed

 7083.

Heterodimer formation of RcsB and BglJ expands the role of the Rcs two-component system and the network of regulators affecting the bgl promoter via H-NS repression.[BglJ; RcsB; H-NS] (Mus musculus) PubMed

 7084.

Aah and AIDA-I are transcribed in a growth-dependent fashion, mainly at the start of the stationary phase. [AIDA-I] (Mus musculus) PubMed

 7085.

Snl6 is required for NH1-mediated resistance to Xanthomonas oryzae pv. oryzae.[Snl6, NH1] (Mus musculus) PubMed

 7086.

the involvement of quelling defective-2 interacting protein (qip(+)), a Neurospora gene whose function is essential to silencing by quelling, in meiotic silencing, and normal sexual development [QIP] (Mus musculus) PubMed

 7087.

Presented is the cryo-electron microscopy structures of tmRNA-SmpB accommodated or translocated into stalled ribosomes.[SmpB] (Mus musculus) PubMed

 7088.

Translesion synthesis efficiency of Pol eta depends critically on the size of the bulky adduct forming the lesion.[DNA polymerase eta] (Mus musculus) PubMed

 7089.

The ability of p8 to simultaneously anergize and cluster T cells, together with its induction of cellular conduits, secures virus propagation while avoiding the host's immune surveillance.[p8] (Mus musculus) PubMed

 7090.

We conclude that VP4 protein appears as a product of RNA encapsidation, and that defective processing of capsid proteins precludes genome encapsidation. [VP4] (Mus musculus) PubMed

 7091.

These results indicate that the competitive advantage of the rpoS(Ty19) mutant is dependent on Crl and suggest that crl plays a role in the appearance of rpoS mutants in bacterial populations.[crl; rpoS] (Mus musculus) PubMed

 7092.

QDE-2-interacting protein is important for the production of single-stranded siRNA during Quelling [QIP] (Mus musculus) PubMed

 7093.

SUB1 is the first putative serine protease experimentally described for T. vaginalis. [Sub1] (Mus musculus) PubMed

 7094.

The authors demonstrating that Escherichia coli laminin-binding fimbriae , encoded by ycbQRST, contributes to adherence to human intestinal epithelial cells and to cow and pig gut tissue in vitro.[ycbS & T] (Mus musculus) PubMed

 7095.

study describes how Gwl activation results in PP2A inhibition; identified Arpp19 and alpha-Endosulfine that, when phosphorylated by Gwl, associate with and inhibit PP2A promoting mitotic entry [Greatwall, Gwl) (Mus musculus) PubMed

 7096.

the position of the triphosphate group (5' and not 3') on the ribose/deoxyribose ring is important for recognition by ANT(4'); NTPs with larger substituents at the 3'-position of the ribose ring are not cosubstrates for ANT(4'). [ANT9(4')] (Mus musculus) PubMed

 7097.

conformational transitions in an oligomeric and high molecular weight class II alpha-mannosidase from Aspergillus fischeri [class II alpha-mannosidase] (Mus musculus) PubMed

 7098.

dst1 encodes a homolog of WC-1, a fungal blue-light photoreceptor first identified in Neurospora crassa, while dst2 encodes a novel protein with a putative flavin adenine dinucleotide (FAD)-binding-4 domain.[dst1 & dst2] (Mus musculus) PubMed

 7099.

Two putative mosquito glutamate decarboxylase-like enzymes of mosquitoes were expressed and their substrate specificity and biochemical properties, were analyzed. [GDC] (Mus musculus) PubMed

 7100.

Two putative mosquito glutamate decarboxylase-like enzymes of mosquitoes were expressed and their substrate specificity and biochemical properties, were analyzed.[ADC] (Mus musculus) PubMed

 7101.

a large-scale comprehensive study to determine the genotype of Helicobacter pylori cagA gene in Hong Kong (Mus musculus) PubMed

 7102.

Results identified a Leishmania major-specific gene that can partly compensate for the loss of virulence observed for L. major HSP100 null mutants [Hsp100]. (Mus musculus) PubMed

 7103.

The GRAS Domain of SLR1 Stabilizes the Interaction between GID1 and SLR1. [GID1; SLR1] (Mus musculus) PubMed

 7104.

Grapevine rupestris stem pitting-associated virus capsid protein contains a nuclear localization signal "KRKR" near its N-terminus, which is conserved among all five strains whose genomes are completely sequenced.[capsid protein] (Mus musculus) PubMed

 7105.

Extracellular pH controls the ZmSUT1 and UmSRT1 at the host/pathogen interface. [SRT1] (Mus musculus) PubMed

 7106.

There were a total of 14 single nucleotide polymorphisms (SNPs) in KRTAP1-4 identified and these SNPs tended to be clustered in two regions.[KRTAP1-4] (Mus musculus) PubMed

 7107.

Purine starvation induces upregulation of the purine permease NT1 in wild-type parasites. [NT1] (Mus musculus) PubMed

 7108.

MC159 is a dual-function immune modulator that regulates host cell death as well as NF-kappaB responses by innate immune signaling receptors. (MC159) (Mus musculus) PubMed

 7109.

Mutations in both EspP1-25 and L22 suppress the aggregation of a cytoplasmic protein containing EspP1-25. [EspP] (Mus musculus) PubMed

 7110.

The crystallographic structures of Encephalitozoon cuniculi Iws1 and the Iws1/N-terminal region of Spt6 complex reveal two conserved binding subdomains in Iws1. [Iws1, Spt6] (Mus musculus) PubMed

 7111.

mutational analysis and crystallography of aminoacylhistidine dipeptidase from Vibrio alginolyticus reveal a new architecture of M20 metallopeptidases [PepD] (Mus musculus) PubMed

 7112.

Analysis of the expression pattern of wheat TaPDS and TaZDS in different tissues revealed that the transcripts levels were higher in leaves and flowers petals, followed by in inflorescences, and were nearly absent in the roots and seeds.[PDS] (Mus musculus) PubMed

 7113.

sigma factor SigV plays a key role in the original model of lysozyme resistance and virulence of Enterococcus faecalis [SigV] (Mus musculus) PubMed

 7114.

Adc1 is expressed in leaf, root & stem. Adc2 encodes a 629-AA protein, predicted M.W. 67 kDa. The Adc2 gene has an intron & a short upstream open reading frame in the 5'-UTR. Its expression is restricted to stem tissue. ADC1. ADC2. (Mus musculus) PubMed

 7115.

In C. elegans, Zfr mRNA expression was barely detectable in the fertilized egg and the L1 stage, but increased in the adult organism (Mus musculus) PubMed

 7116.

CagA exploits a polarity-signaling pathway to induce oncogenesis [CagA] (Mus musculus) PubMed

 7117.

crystal structure of RibU, the S component of the ECF-type riboflavin transporter from Staphylococcus aureus at 3.6-A resolution [ribU] (Mus musculus) PubMed

 7118.

Rmi1 serves to stimulate DNA decatenation, removing the last linkages between the repaired and template DNA molecules. (Mus musculus) PubMed

 7119.

RFC(Ctf18) is essential for the Mrc1-dependent activation of Rad53 and for the maintenance of paused replication forks. [Ctf18] (Mus musculus) PubMed

 7120.

Pif1 and Exo1 are required for different nuclease activities that generate ssDNA and activate the DNA damage checkpoint following Cdc13 inactivation.[Pif1, Exo1] (Mus musculus) PubMed

 7121.

The authors show that RCO-1 and RCM-1 participate in the light-transduction pathway of Neurospora and has a role in photoadaptation by repressing gene transcription after long exposures to light.[RCM-1] (Mus musculus) PubMed

 7122.

These data suggest that POR1 encodes a transcriptional activator widely regulating fatty acid metabolism in Y. lipolytica. [POR1] (Mus musculus) PubMed

 7123.

NusG slows down rather than facilitates transcript elongation by its cognate RNA polymerase (NusG). (Mus musculus) PubMed

 7124.

The crystal structure reveals that the P2 C protein forms a symmetric dimer oriented to bind the major groove of two consecutive turns of the DNA (C protein). (Mus musculus) PubMed

 7125.

A comparison of the structure of NpmA with KamB from the Streptoalloteichus tenebrarius provides insights into the likely molecular mechanisms of action of the A1408 methyltransferases (NpmA). (Mus musculus) PubMed

 7126.

Mutations of conserved, polar residues within the K-channel block or inhibit steady state aa3 oxidase activity. (aa3-type cytochrome c oxidase) (Mus musculus) PubMed

 7127.

PIFTC3, an orthologue of nematode DYF-13, participates in a macromolecular complex with components of both IFT-A and IFT-B. [PIFTC3] (Mus musculus) PubMed

 7128.

The expression pattern of the MtF3H gene was analyzed.[F3H] (Mus musculus) PubMed

 7129.

p13 might control key processes regulated through Ca2+ signaling such as activation and death of T cells, the major targets of HTLV-1 infection. (p13) (Mus musculus) PubMed

 7130.

These results indicate that PriA is involved in the discontinuous synthesis of nascent DNA.[PriA] (Mus musculus) PubMed

 7131.

A novel Ras small monomeric GTPase Rsr1 gene, designated PmRsr1, from yeast-form Penicillium marneffei, was isolated and characterized.[PmRsr1] (Mus musculus) PubMed

 7132.

Substrate specificity of Os3BGlu7 and HvBII depends on the inherent conformational and spatial flexibilities of gluco- and manno-configured substrates in the enzymes' active sites [Os3BGlu7] (Mus musculus) PubMed

 7133.

The ABC efflux system PatA/PatB is induced upon exposure to subinhibitory concentrations of fluoroquinolones, whether substrates of the transporter or not.[PatA & PatB] (Mus musculus) PubMed

 7134.

The eukaryotic gamma subunit of eukaryotic translation initiation factor 2 is able to bind by itself the initiator tRNA. The two peripheral alpha and beta subunits are required for strong binding. [eukaryotic translation initiation factor 2] (Mus musculus) PubMed

 7135.

The results of a 200-ns molecular dynamics simulation of the sodium-dependent galactose cotransporter vSGLT, are reported.[vSGLT] (Mus musculus) PubMed

 7136.

The observed dynamics shows that Phosphoglycerate kinase has the flexibility to allow fluctuations and displacements that seem to enable the function of the protein.[PGK] (Mus musculus) PubMed

 7137.

The interaction of human adenovirus E4orf4 with both Cdc55 and B55 involves residues within blades 1 and 2, a finding that is consistent with the idea that E4orf4 binding may block the dephosphorylation of at least some PP2A substrates. [cdc55] (Mus musculus) PubMed

 7138.

These results indicated that the hydrophobic domain of infectious bronchitis virus E protein alters the host secretory pathway to the apparent advantage of the virus. (Mus musculus) PubMed

 7139.

NSP1 suppresses protein sythesis in mammalian cells and Hela cells extracts but not rabbit reticulocytes. [NSP1] (Mus musculus) PubMed

 7140.

Infection of chickens with R65(mono)-S-ETR or R65(mono)-S-ER clevage site in haemagglutinin led to slight transient respiratory symptoms, whereas R65-infected animals died within 2 days.[haemagglutinin] (Mus musculus) PubMed

 7141.

The authors demonstrate that NS1 of the highly pathogenic avian influenza A/Duck/Hubei/L-1/2004 (H5N1) virus interacts with human Ubc9 and SUMO1 is conjugated to H5N1 NS1 in both transfected and infected cells.[NS1] (Mus musculus) PubMed

 7142.

RCMV miRNA miR-r111.1-2 is highly expressed in the salivary glands and miR-R87-1 is expressed in most tissues during the acute infection phase in vitro and in vivo and associated with a stage of viral infection.[miR-r111.1-2, miR-R87] (Mus musculus) PubMed

 7143.

Translocation and unwinding by single DnaB molecules in three tethered DNA geometries held under tension, was investigated.[DnaB] (Mus musculus) PubMed

 7144.

The results suggest a two-step opening mechanism that gives rise first to a semi-open conformation upon adsorption of the lipase at the water/organic solvent interface, followed by a further opening of the lid upon substrate binding.[Lipase] (Mus musculus) PubMed

 7145.

The small hydrophobic (SH) protein of JPV plays a role in inhibiting TNF-alpha expression. [SH protein] (Mus musculus) PubMed

 7146.

These data indicate that Atf1p plays a direct and specific role in targeting integration in the promoter of fbp1. [Atfp1, fbp1] (Mus musculus) PubMed

 7147.

The interaction of human adenovirus E4orf4 with both Cdc55 and B55 involves residues within blades 1 and 2, a finding that is consistent with the idea that E4orf4 binding may block the dephosphorylation of at least some PP2A substrates. [E4ORF4] (Mus musculus) PubMed

 7148.

A detailed computational model of CaMKII and PKA signaling in cardiac myocytes that provides unique insights into their regulation of normal and pathological Ca(2+) handling, was developed.[CaMKII] (Mus musculus) PubMed

 7149.

Sororin and Eco2 work together to form a unique regulatory module that limits cohesion to cells with replicated chromatin and support a model in which cohesion in vertebrates is not fully established until the G2 phase of the cell cycle. [Eco2] (Mus musculus) PubMed

 7150.

2 genes: Low Rif2 content marks short telomeres for preferential elongation. [Rif2] The absence of Mec1 at short telomeres target them for preferential elongation. [Mec1] (Mus musculus) PubMed

 7151.

Neurovirulence of interferon-resistant rabies virus correlates with the capacity of the virus phosphoprotein to prevent activation of IRF3 and IRF7. (Mus musculus) PubMed

 7152.

These data suggest that PB1-F2 N66S may contribute to the delay of innate immune responses, allowing for unchecked viral growth and ultimately severe immunopathology observed in the lungs.[PB1-F2] (Mus musculus) PubMed

 7153.

This work shows a second binding site for divalent metal cations in phosphofructokinase-2 and by means of substitution studies establishes that, besides Mg2+, Mn2+ can interact at this site and with a higher affinity than Mg2+. [phosphofructokinase-2] (Mus musculus) PubMed

 7154.

Identify semaphorin 3G (Sema3G) as a primarily endothelial cell-expressed class 3 semaphorin that controls endothelial and smooth muscle cell functions in autocrine and paracrine manners. (Mus musculus) PubMed

 7155.

Bacteriophage Sf6 virion contains two proteins, OmpA and OmpC, from its host Shigella flexneri.[OmpA and OmpC] (Mus musculus) PubMed

 7156.

The structure of Hbs1 with and without GDP and a low-resolution model of the Dom34-Hbs1 complex is presented. [Hbs1] (Mus musculus) PubMed

 7157.

A Bo10 deletion virus was viable but showed a growth deficit associated with reduced binding to epithelial cells.[Bo10] (Mus musculus) PubMed

 7158.

The Walleye dermal sarcoma virus cyclin functions as a structural ortholog of cyclin C in spite of its limited amino acid sequence identity with C cyclins or with any known cyclins and activates Cdk8 and Cdk3.[cyclin] (Mus musculus) PubMed

 7159.

The authors report that a protein encoded in the 34-kbp genome of the rudivirus SIRV1 is a member of the replication initiator (Rep) superfamily of proteins, which initiate rolling-circle replication (RCR) of diverse viruses and plasmids. (Mus musculus) PubMed

 7160.

In the present study, it was shown that ShvR negatively regulates its own expression, as is typical for LysR-type regulators.[ShvR] (Mus musculus) PubMed

 7161.

This study combined different approaches to investigate the role and mechanism of sigma(E)-dependent activation in X. campestris pv. campestris. (Mus musculus) PubMed

 7162.

The V-ATPase accessory subunit Ac45 represents the first regulator of the proton pump and controls V-ATPase-mediated granular acidification that is necessary for efficient prohormone processing.[Ac45] (Mus musculus) PubMed

 7163.

The entire extra-cellular region of PrkC (residues 378-664), containing three predicted PASTA domains and an extra-domain of unknown function, has been successfully crystallized using vapor-diffusion methods[PrkC] (Mus musculus) PubMed

 7164.

Vps4 functions as a stable oligomer that acts upon individual Endosomal Sorting Complexes Required for Transport [ESCRT-III] subunits to facilitate ESCRT-III disassembly.[Vps4] (Mus musculus) PubMed

 7165.

The Cdk1 kinase and two Cdk phosphorylation sites in the nucleoporin Nup1 were required for peripheral targeting of INO1 and GAL1.[Cdk1, Nup1, INO1, GAL1] (Mus musculus) PubMed

 7166.

RNase MRP was involved in viral (Tomato Bushy stunt virus) RNA degradation and RNA recombination in a Saccharomyces cerevisiae model host.[Rnase MRP] (Mus musculus) PubMed

 7167.

The data presented in this study demonstrate that PB2-E158G is a novel pathogenic determinant of pandemic influenza A viruses H1N1 and H5 in the mouse model. [PB2] (Mus musculus) PubMed

 7168.

miR-M3 blocked cisplatin-induced apoptosis by directly downregulating Smad2 protein expression.[miR-M3] (Mus musculus) PubMed

 7169.

These results support the proposal that SoxR senses redox-active molecules, such as actinorhodin in S. coelicolor, and induces a protective function against them.[SoxR] (Mus musculus) PubMed

 7170.

The genetic analysis reported here also reveals that the slow growth and other defects associated with inactivation of rluD in E. coli K-12 strains are due to a defective RF2 protein, with a threonine at position 246, which is present in all K-12 strains. (Mus musculus) PubMed

 7171.

OsOxi1 positively regulates defense responses through the phosphorylation of OsPti1a. [OsOxi1; OsPti1a] (Mus musculus) PubMed

 7172.

report describes a lack of association between H. pylori CagA-protein polymorphisms and pathogenesis [CagA] (Mus musculus) PubMed

 7173.

The study provides molecular details of how yeast frataxin (Yfh1) interacts with Isu1 as a structural module to improve our understanding of the multiprotein complex assembly that completes Fe-S cluster assembly. [Yfh1, Isu1] (Mus musculus) PubMed

 7174.

Isolated ExbB adopts a stable homooligomer with four to six monomers.[ExbB] (Mus musculus) PubMed

 7175.

Reported are several high-resolution crystal structures of the nicotinamidase from Streptococcus pneumoniae (SpNic) in unliganded and ligand-bound forms. [SpNic] (Mus musculus) PubMed

 7176.

These data show that PfHslV is located to the plasmodial mitochondrion and presumably has vital function within this organelle which makes it an attractive target for interventions.[PfHslV] (Mus musculus) PubMed

 7177.

in pandemic 2009 H1N1 isolates, the H1N1v NS1 gene was more conserved than previous epidemic strains; a closer genetic identity of H1N1v with the swine than the human reference strains was shown; hot-spots were shown in the H1N1v NS1 aa sequence [NS1] (Mus musculus) PubMed

 7178.

These results indicate that CRP functions as an essential activator, whereas SmcR functions in the presence of CRP for full vvpE expression.[CRP, SmcR & vvpE] (Mus musculus) PubMed

 7179.

We show that White Collar Complex directly controls the expression of 24 transcription factor genes, including the clock-controlled adv-1 gene, which controls a circadian output pathway required for daily rhythms in development. [adv-1] (Mus musculus) PubMed

 7180.

The silencing of MTL3 locus requires the yKu70, yKu80, and Rif1 proteins. [yKU70, Yku80, Rif1] (Mus musculus) PubMed

 7181.

A novel GlcNAc-induced gene, GIG1, which is not essential for GlcNAc catabolism or the induction of hyphae, was identified and is required for fro sensitivity to nikkomycin z.[GIG1] (Mus musculus) PubMed

 7182.

Three PABP (poly(a) binding protein) homolouges are simultaneousy expressed but differ in protein and RNA binding properties and in subcellular localization under conditions of transcription inhibition. [PABP1, PABP2, PABP3]. (Mus musculus) PubMed

 7183.

Both cholesterol and the putative bile salt efflux pump HefC play important roles in H. pylori resistance to bile salts and ceragenins.[HefC] (Mus musculus) PubMed

 7184.

This study demonstrated that disruption of the fadD gene has marked effects on expression of the ToxR virulence regulon, especially TcpP, motility, and in vivo lethality of V. cholerae.[TcpP] (Mus musculus) PubMed

 7185.

structure of c-Rph1 is composed of a JmjN (Jumonji N) domain, a long beta-hairpin, a mixed structural motif and a JmjC domain[Rph1] (Mus musculus) PubMed

 7186.

crystal structure of Lassa virus NP at 1.80 A resolution, which reveals amino (N)- and carboxy (C)-terminal domains with structures unlike any of the reported viral NPs [NP] (Mus musculus) PubMed

 7187.

The the DNA double-strand breaks (DSB) resection and procrossover functions of Exo1 during meiosis involve temporally and biochemically distinct activities. (EXO1 protein, S cerevisiae) (Mus musculus) PubMed

 7188.

Gene disruption of bcass1 was carried out and generated a strict auxotroph, unable to grow without exogenous arginine supplementation.[Bcass1] (Mus musculus) PubMed

 7189.

Taken together, these observations support the conclusion that ChxR, in the absence of phosphorylation, exhibits many of the characteristics of a phosphorylated (active) OmpR/PhoB subfamily response regulator.[ChxR] (Mus musculus) PubMed

 7190.

Covalently modified by oligo-(R)-3-hydroxybutyrates (cOHB) conjugated residues in the ion pathway, S102 and S129 were mutated to determine the influence of cOHB on channel properties.[KcsA] (Mus musculus) PubMed

 7191.

Methionine sulfoxide reductases MsrA and MsrB are involved in the regulation of mitochondrial function. [MsrA,MsrB] (Mus musculus) PubMed

 7192.

[gag p24] Cytotoxic T cell escape at arginine264 in a conserved epitope of HIV gag p24 is a major determinant of subsequent viral load in HLA-B*27-positive individuals with HIV infection. (Mus musculus) PubMed

 7193.

OsSIZ1 and OsSIZ2 are localized to the nucleus and function as SUMO E3-ligases. [Siz2] (Mus musculus) PubMed

 7194.

VX-4 might function as a hemoglobinase in the acidic parasite food vacuole, a maturase of Plasmodium vivax plasmepsin 4 at neutral or acidic pH, and a cytoskeleton-degrading protease in the neutral erythrocyte cytosol.[VX-4] (Mus musculus) PubMed

 7195.

Prm1, a pheromone-regulated membrane glycoprotein, functions on the plasma membrane at sites of cell-cell contact and enhances fusion during mating. [Prm1] (Mus musculus) PubMed

 7196.

The transcriptional activator Met4 functions as a substrate-specificity factor in the context of SCF(Met30/Met4) to coordinate cofactor degradation with its own activity status. (MET4 protein, S cerevisiae) (Mus musculus) PubMed

 7197.

A network of cell wall proteins comprising Als3p, Hwp1p, and Eap1p, with complementary adhesive functions, promotes interactions of C. albicans with host and bacterial molecules, and effective colonization within polymicrobial communities. [Hwp1p, Eap1p] (Mus musculus) PubMed

 7198.

The brassinosteroid (BR)-induced initial H(2)O(2) production activates ZmMPK5, which is involved in self-propagation of apoplastic H(2)O(2) via regulation of NADPH oxidase gene expression in BR-induced antioxidant defence systems.[NADPH oxidase] (Mus musculus) PubMed

 7199.

inactivation of katA (catalase) and sodA (Superoxide dismutase) hypersensitive to seawater stress at 4 degrees C (Mus musculus) PubMed

 7200.

Here we show that the vesicle-associated protein Sec4 localizes to a subapical spot, confirming that secretory vesicles accumulate in the putative C. albicans Spitzenkorper. [Sec4] (Mus musculus) PubMed

 7201.

PilA and SurG are necessary for conidial eisosome organization in ways that differ from those for their S. cerevisiae homologues. [PilA, SurG] (Mus musculus) PubMed

 7202.

Slab is required for endocytosis and polarity maintenance in hyphae. [SLaB] (Mus musculus) PubMed

 7203.

Tthe N terminus of phophosidesterases PDEB1 and PDEB2 is essential for determining the flagellar skeleton location of PDEB1, and the cell body location of PDEB2. [PDEB1, PDEB2] (Mus musculus) PubMed

 7204.

SsgB promotes the polymerization of FtsZ. [ssgB and FtsZ] (Mus musculus) PubMed

 7205.

crystal structure of Dhaf4260 from Desulfitobacterium hafniense DCB-2 was determined by single-wavelength anomalous diffraction (SAD) to a resolution of 2.01 A[Dhaf4260 ] (Mus musculus) PubMed

 7206.

New interactions of PthAs with citrus proteins involved in protein folding and K63-linked ubiquitination, are described.[PthA] (Mus musculus) PubMed

 7207.

While Pif1 is a monomer in solution, the study shows that binding of ssDNA to Pif1 induces protein dimerization. [Pif1] (Mus musculus) PubMed

 7208.

These findings are consistent with the idea that RNA silencing is an antiviral defence mechanism and that the counter-defence role of P25 is through the degradation of AGO proteins via the proteasome pathway.[P25] (Mus musculus) PubMed

 7209.

Described is the 2.0 A resolution crystal structure of RB69 DNA polymerase.[DNA polymerase] (Mus musculus) PubMed

 7210.

crystals of Swi5 and Swi5-DeltaN180Sfr1 are likely to contain one tetramer and two heterodimers in the asymmetric unit, respectively[Swi5 and Sfr1] (Mus musculus) PubMed

 7211.

crystal of formate oxidase was orthorhombic and belonged to space group C222(1)[ formate oxidase] (Mus musculus) PubMed

 7212.

In this study, Quantum Mechanics/Molecular Mechanics rare event trajectories from the transition state structures of the rate limiting step of the thymidylate synthase catalyzed reaction have been carried out. [thymidylate synthase] (Mus musculus) PubMed

 7213.

results demonstrate that the ClC subunit alone is the basic functional unit for transport and that cross-subunit interaction is not required for Cl(-)/H(+) exchange in ClC transporters [ClC-ec1] (Mus musculus) PubMed

 7214.

ROA plays multiple roles in maintaining the proper morphology and discharge of ascospores in G. zeae[ROA] (Mus musculus) PubMed

 7215.

These results suggest that the translation initiation efficiency of the antiterminator proteins, at least in part, determines whether the target genes are subject to glucose repression.[BglG & BglG2] (Mus musculus) PubMed

 7216.

The structure of the complement-binding domain of Staphylococcus aureus protein Sbi (Sbi-IV) in complex with ligand C3d is presented.[Sbi] (Mus musculus) PubMed

 7217.

only the GTPase domains are required for the mitochondrial inheritance function of Gem1p [Gem1p] (Mus musculus) PubMed

 7218.

Substance P and SP-R mRNA expressions were reduced after IMETIT treatment of allergic rhinitis. (Mus musculus) PubMed

 7219.

expression of rv-cyclin protects the fish liver from carcinogen damage and delays onset of malignancy (Mus musculus) PubMed

 7220.

newly synthesized Cox1 physically interacts with a complex of proteins involving Ssc1, Mss51, and Cox14 [Cox25][Mss51][Ssc1][Cox14][Cox1] (Mus musculus) PubMed

 7221.

These results suggested that Rice ragged stunt virus Pns6 functions as a virus suppressor of RNA silencing that targets an upstream step of the dsRNA formation in the RNA silencing pathway.[Pns6] (Mus musculus) PubMed

 7222.

biochemical and structural characterization of an effector protein (NleL) from Escherichia coli O157:H7, a widespread pathogen causing severe foodborne diseases [NleL] (Mus musculus) PubMed

 7223.

TcMAPK2 has an important role in the stress response of Trypanosoma cruzi and may be important in regulating proliferation and differentiation (MAPK2). (Mus musculus) PubMed

 7224.

The crystal structure of Leishmania major ADP-ribosylation factor-like 1 (ARL1) in complex with GDP has been determined to 2.1 A resolution and reveals a high degree of structural conservation with human ADP-ribosylation factor 1 (ARF1). [Arf1] (Mus musculus) PubMed

 7225.

hepatitis C virus infection can induce endoplasmic reticulum stress, with NS2 protein being a major mediator.(NS2 PROTEIN) (Mus musculus) PubMed

 7226.

Together, these results demonstrated that the induction of CXCL8 in human neutrophils activated by Streptococcus pneumoniae PspA and PspC was regulated by p38 MAPK and NF-kappaB pathways.[PspA & PspC] (Mus musculus) PubMed

 7227.

prevalence of different ga2 alleles within teosinte and maize was evaluated, and the implications of this distribution on a role for the Ga2 system in the reproductive isolation of Zea subspecies are discussed[ga2] (Mus musculus) PubMed

 7228.

analysis ofAP-1 mu1A and mu1B expression revealed tissue-specific expression for either one during embryogenesis and in adult tissues in contrast to their expression in mammalia [AP-1 mu1A and mu1B (Mus musculus) PubMed

 7229.

The double null lys21Delta/lys22Delta mutant lacked homocitrate synthase activity and exhibited lysine auxotrophy in minimal media that could be fully rescued by the addition of 0.5-0.6 mM L-lysine.[lys22] (Mus musculus) PubMed

 7230.

Specific expression in the growing part of rice leaves is well in agreement with the role of SUB1A in suppressing leaf elongation under submergence.[SUB1A] (Mus musculus) PubMed

 7231.

The amino acid substitutions in conserved sequences of penicillin-binding proteins 2B, 1A and 2X increase MIC for beta-lactam antibiotics. (Mus musculus) PubMed

 7232.

analysis of positional importance of aromatic residues and lysine in the interactions of peptides with the Plasmodium falciparum Hsp70-1 (Mus musculus) PubMed

 7233.

A single dominant gene, Ml3D232, confers resistance in the host seedling stage.[M13D232] (Mus musculus) PubMed

 7234.

Presented is the structure of the class II ribonucleotide reductase tmNrdJ from Thermotoga maritima in three complexes: (i) with allosteric effector deoxythymidine triphosphate, substrate GDP, and adenosylcobalamin. [tmNrdJ] (Mus musculus) PubMed

 7235.

Trypanosoma brucei Tob55 is essential for cell survival and is required for VDAC assembly on outer mitochondrial membrane. [Tob55] (Mus musculus) PubMed

 7236.

the histidine coordination and stability of the [2Fe-2S] cluster in the Fra2-Grx3 complex are essential for iron regulation in yeast [Fra2][Grx3] (Mus musculus) PubMed

 7237.

Results suggest that bradykinin is involved in parainfluenza-3 virus-induced inflammatory cell influx and airway hyperreactivity.(bradykinin, i.e., kininogen 1/kng1 gene) (Mus musculus) PubMed

 7238.

ArcA, acting independently of acetate metabolism, is also required for maximum lifespan extension in the lipA and lpdA mutants, indicating that these mutations promote entry into a mode normally associated with a low-oxygen environment [ArcA] (Mus musculus) PubMed

 7239.

The putative WRKY transcription factor OsWRKY80 is up-regulated in rice leaves, stems and roots after Fe-excess treatment.[OsWRKY80] (Mus musculus) PubMed

 7240.

Changes in biomass yield, food characteristics, and genetic stability of S. cerevisiae strains overexpressing HAP4 are reported.[HAP4] (Mus musculus) PubMed

 7241.

two chitin-binding proteins (BmPM-P43 and BmPM-P41) from the peritrophic membrane of the silkworm, Bombyx mori, were identified and cloned (Mus musculus) PubMed

 7242.

FATP1 gene polymorphisms were associated with chicken carcass traits or was linked with the major gene.[FATP1] (Mus musculus) PubMed

 7243.

XA13, COPT1, and COPT5 are associated with Cu redistribution in rice. Activating Xa13 makes plants susceptible to bacterial blight disease. (Mus musculus) PubMed

 7244.

Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans. [GSR-1 glutathione reductase] (Mus musculus) PubMed

 7245.

study of the sodium/galactose transporter from Vibrio parahaemolyticus (vSGLT), consisting of molecular dynamics simulations, biochemical characterization and a new crystal structure of the inward-open conformation at a resolution of 2.7 A [vSGLT] (Mus musculus) PubMed

 7246.

RelA is cleaved by chlamydial protease-like activity factor (CPAF), which impairs proinflammatory signaling in cells infected with Chlamydiae; IL-1beta-dependent secretion of IL-8 is also reduced by CPAF expression [CPAF] (Mus musculus) PubMed

 7247.

These findings suggest that trimethylation of pilA1 at the C-terminal lysine may be essential for the biogenesis of functional pili.[pilA1] (Mus musculus) PubMed

 7248.

sbrA and sbrB were found to contain open reading frames encoding small, highly basic peptides that are conserved among Staphylococci, SbrC did not contain any likely open reading frame and thus constitute a genuine non-coding sRNA [SbrA, SbrB,SbrC] (Mus musculus) PubMed

 7249.

Adhesion is mediated through Scl1 on bacterial surface and protein receptor(s) on epithelial cells. [Scl1] (Mus musculus) PubMed

 7250.

The direct and functional interaction of SCO3201 with the promoter region of scbA, a gene under the positive control of the TetR-like regulator, ScbR, was indeed demonstrated by in vitro as well as in vivo approaches.[SCO3201] (Mus musculus) PubMed

 7251.

Pseudouridylation of RNA can be induced at sites of imperfect sequences, and Pus7p and snR81 RNP can catalyse both constitutive and inducible pseudouridylation [SnR81 RNP, Pus7p] (Mus musculus) PubMed

 7252.

The repair defect caused by the triple deletion of Pph3, Ptc2, and Ptc3 is most prominent when a DSB is slowly repaired and the DNA damage checkpoint is fully activated.[Pph3, Ptc2, Ptc3] (Mus musculus) PubMed

 7253.

Eleven human host proteins interacting with Core and 45 interacting with NS4B were identified.[NS4B, Core protein] (Mus musculus) PubMed

 7254.

Enzymatic activity of virulence factors ecreted aspartyl proteinase and phospholipase were found to be significantly high in amphotericin-B resistance strains. [aspartyl proteinase, phospholipase] (Mus musculus) PubMed

 7255.

genes encoding TcCox10 and TcCox15 are responsible for coding heme O and heme A synthases and are differentially transcribed during the parasite life cycle [TcCox10] [TcCox15] (Mus musculus) PubMed

 7256.

Vba2p is involved in basic amino acid transport in S. pombe under diverse conditions [Vba2p] (Mus musculus) PubMed

 7257.

[IL-21; interleukin-21] Multiple signaling pathways involved in IL-21-induced expression of interferon-gamma, interleukin (IL)-10, and IL-22 have been found to be involved in recombinant rainbow trout IL-21 signaling. (Mus musculus) PubMed

 7258.

demonstrating that GRA15 alone is sufficient for NF-kappaB activation[GRA15] (Mus musculus) PubMed

 7259.

Data show that loss-of-function mutations of moc-3 and dph-3 effectively suppress the Multivulva (Muv) phenotype of the lin-1(e1275, R175Opal) mutation: [MOC-3 & DPH-3] (Mus musculus) PubMed

 7260.

Data suggest that mus-10 is involved in mitochondrial maintenance: [MUS-10] (Mus musculus) PubMed

 7261.

Study provides insights into the comprehensive signaling networks orchestrated by carbonic anhydrase Can2/CO2-sensing pathways in Cryptococcus neoformans strain H99: [Can2] (Mus musculus) PubMed

 7262.

These results suggest a suppressive effect of HBZ on Maf function, which may have a significant role in HTLV-1 related pathogenesis [HBZ]. (Mus musculus) PubMed

 7263.

The importance of Hsc70 in AtlE adhesin-mediated internalization was demonstrated by the inhibition of Staphylococcus aureus internalization with anti-Hsc70 antibodies.[AtlE] (Mus musculus) PubMed

 7264.

The reduction of virulence in the trag mutant compared to the wild-type in animal model systems, laid the foundation for further studies.[trag] (Mus musculus) PubMed

 7265.

Several attempts to delete the mahrp2 gene failed, indicating that the protein is essential for parasite survival.[MAHRP2] (Mus musculus) PubMed

 7266.

In summary, FlbC is a putative nuclear transcription factor necessary for proper activation of conidiation, and its balanced activity is crucial for governing growth and development in Aspergillus nidulans.[FlbC] (Mus musculus) PubMed

 7267.

The authors conclude that DAC1 and DAC3 play distinct roles in subtelomeric gene silencing and that DAC3 represents the first readily druggable target linked to variant surface glycoprotein expression sites control.[DAC1 & DAC3] (Mus musculus) PubMed

 7268.

Studies identified the stem-loop precursor structure of miR-363 and 363* followed by their temporal and spatial expression patterns in chicken embryo at the stage of E3.5-6.5 d: [miR-363 and 363*] (Mus musculus) PubMed

 7269.

Mutations of R102 cause accumulation of extrachromosomal ribosomal DNA circles and reduce life span, suggesting that histone H2B contributes to longevity. (Mus musculus) PubMed

 7270.

These biochemical data suggest that DPAP1 accelerates the production of amino acids from hemoglobin by bridging the gap between the endopeptidase and aminopeptidase activities of the food vacuole.[DPAP1] (Mus musculus) PubMed

 7271.

In conclusion, Clostridium botulinum C2 toxin is endocytosed by dynamin-dependent mechanisms and we provide evidence for involvement of clathrin and Rho.[Clostridium botulinum C2 toxin] (Mus musculus) PubMed

 7272.

Thus TgSUB1 is involved in micronemal protein processing and regulation of adhesive properties of macromolecular adhesive complexes involved in host cell invasion.[SUB1] (Mus musculus) PubMed

 7273.

The three-dimensional (3D) structure of Dnm1 in a GTP-bound state has been determined. (Mus musculus) PubMed

 7274.

Vibrio cholerae anaerobic induction of virulence gene expression is controlled by thiol-based switches of virulence regulator AphB [AphB] (Mus musculus) PubMed

 7275.

Sum1 and Sok2, which regulate IME1, bind to nonperfect consensuses within nonconserved regions in the sensu stricto Saccharomyces strains.[IME1] (Mus musculus) PubMed

 7276.

Rab proteins and PI4P collaborate in the association of secretory compartments with Myo2p.[Myosin V] (Mus musculus) PubMed

 7277.

CgPMU2 has neofunctionalized to become a broad range, phosphate starvation-regulated acid phosphatase, which functionally replaces PHO5 in Candida glabrata.[CgPMU2] (Mus musculus) PubMed

 7278.

NdeA-B and ndiA encode external and internal alternative NADH dehydrogenases. [NdeA-B, ndiA] (Mus musculus) PubMed

 7279.

Purified sialidase released sialic acid from diverse substrates such as mucin, fetuin, epithelial cell glycans and colominic acid (sialidase). (Mus musculus) PubMed

 7280.

SPO11 is essential for homologous chromosome pairing and crossover formation. [Spo11] (Mus musculus) PubMed

 7281.

RGD1 overexpression restricted hyphae growth. [Rgd1] (Mus musculus) PubMed

 7282.

PbSP interacts with a peptidyl prolyl cis-trans isomerase, calnexin, HSP70 and PWP2. [SP, serine protease] (Mus musculus) PubMed

 7283.

OsABF2 functions as a transcriptional regulator that modulates the expression of abiotic stress-responsive genes through an abscissic acid-dependent pathway.[ABF2] (Mus musculus) PubMed

 7284.

ACS-3-derived long-chain fatty acyl-CoAs, perhaps incorporated into complex ligands such as phosphoinositides, modulate NHR-25 function, which in turn regulates an endocrine program of lipid uptake and synthesis. [ACS-3] (Mus musculus) PubMed

 7285.

The structure of a peptide corresponding to 1.5 units of the PthA repeat domain was solved.[PthA] (Mus musculus) PubMed

 7286.

The ClpX stimulates expression of Staphylococcus aureus spa by Rot dependent and independent pathways. [spa, Rot,ClpX] (Mus musculus) PubMed

 7287.

Alteration AQP1 Ala163 to aspartate, glutamate, and glutamine blocked passage of water, glycerol, and other organic solutes.[AQP1] (Mus musculus) PubMed

 7288.

Molecular dynamics techniques were used to investigate the detailed interactions between the complete tetrameric form of IN and two molecules of the integrase binding domain of LEDGF/p75.[Integrase] (Mus musculus) PubMed

 7289.

Two tandem mitochondrial ribosomal protein L27 genes (mtRPL27a and mtRPL27b), both of which are inactive and leads to F(1) pollen sterility in a cross between O. sativa and O. nivara.[mtRPL27a and mtRPL27b] (Mus musculus) PubMed

 7290.

analysis of how the SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II C-terminal repeat domain [Spt6] (Mus musculus) PubMed

 7291.

The sequence of WciP, a GT2-family glycosyltransferase, indicates that point mutation has compromised linkage specificity, allowing two alternative oligosaccharides to be synthesized.[WciP] (Mus musculus) PubMed

 7292.

Trypanosoma brucei TbDNAH10 was silenced using RNA interference and this resulted in immotile flagella, showing no movement except for occasional slight twitches at the tips.[TbDNAH10] (Mus musculus) PubMed

 7293.

enzymatic properties of the silkworm Na(+)/K(+)-ATPase are suitable for its growth, despite the differences between dog and silkworm Na(+)/K(+)-ATPases[Na(+)/K(+)ATPase] (Mus musculus) PubMed

 7294.

The fhbA gene encoding putative flavohemoglobins expression is correlated to the hyphal growth phenotype. [FhbA] (Mus musculus) PubMed

 7295.

an active and water soluble NDH-2 was obtained [NDH-2] (Mus musculus) PubMed

 7296.

X-ray crystal structure of the DNA-binding domain of the response regulator WalR; specific interactions of WalR with the target DNA [WalR] (Mus musculus) PubMed

 7297.

carbohydrate moieties of arabinogalactan-proteins are degraded by the concerted action of NcAraf1 and Nc6GAL secreted from N. crassa [NcAraf1][Nc6GAL] (Mus musculus) PubMed

 7298.

The results presented here implicate plastidic GS2 in proline production during stress and provide interesting insights into the function of proline in response to drought.[glutamine synthetase GS2] (Mus musculus) PubMed

 7299.

WAF1 is required for a wide range of developmental events by stabilizing miRNAs and ta-siRNAs. [WAF1] (Mus musculus) PubMed

 7300.

Septins are required for proper morphogenesis but dispensable for virulence. [sep1, sep2, sep3, sep4] (Mus musculus) PubMed

 7301.

Data showed that EhPCP5 RGD motif is a ligand for alpha(V)beta(3) integrin-mediated adhesion on colonic cells and represents a novel mechanism to trigger an inflammatory response in the pathogenesis of intestinal amebiasis: [EhPCP5] (Mus musculus) PubMed

 7302.

The greatwall protein as a new regulator of the DNA damage response plays an important role in recovery from DNA damage. (Mus musculus) PubMed

 7303.

SBF and Spt10 cooperate to control the timing of HTA1-HTB1 expression.[Spt10, Swi4] (Mus musculus) PubMed

 7304.

Hepatitis B spliced protein (HBSP) interacts with fibrinogen gamma chain (FGG) and inhibits fibrin polymerization and factor XIIIa-mediated fibrin cross-linking. [HBSP] (Mus musculus) PubMed

 7305.

LytSR two-component system regulates extracellular murein hydrolase activity, bacterial cell death and pyruvate utilization. [murein hydrolase] (Mus musculus) PubMed

 7306.

Data indicate a cooperative role of Aip1 and cofilin in pH-dependent cell migration, and they suggest defective chemotaxis in Ddnhe1(-) cells is determined primarily by loss of cofilin-dependent actin dynamics [Aip1]. (Mus musculus) PubMed

 7307.

Leishmania phenylalanine hydroxylase may mitigate but not alleviate Tyrosine auxotrophy, but plays no essential role in the steps of the parasite infectious cycle.[phenylalanine hydroxylase] (Mus musculus) PubMed

 7308.

Pb1 encodes an atypical R protein-like protein, which confers resistance to rice blast. [Pb1] (Mus musculus) PubMed

 7309.

structural basis and dynamics of precursor recognition by Tom20 [Tom20] (Mus musculus) PubMed

 7310.

Results suggest that OsCPK21 is involved in the positive regulation of the signaling pathways that are involved in the response to ABA and salt stress: [OsCPK21] (Mus musculus) PubMed

 7311.

Solubilized sterol C24-methyltransferase (24-SMT) was purified to homogeneity from a cell extract of the yeast Candida albicans (Mus musculus) PubMed

 7312.

Using Penicillium chrysogenum Pex11, the study shows that this amphipathic helix, termed Pex11-Amph, associates with liposomes in vitro; interaction is evident when liposomes with a content resembling that of peroxisomal membranes are used. [Pex11] (Mus musculus) PubMed

 7313.

Thus, HdpA is the first enzyme belonging to the M23-peptidase family able to perform the d,d-carboxypeptidation and regulate cell shape.[HdpA] (Mus musculus) PubMed

 7314.

Cdc28 kinase localizes to meiotic chromosomes and is necessary for the formation of the synaptonemal complex. [Cdc28] (Mus musculus) PubMed

 7315.

The FLR1 network structure was revised, based on the comparison between simulated and experimental gene expression data.[FLR1] (Mus musculus) PubMed

 7316.

Positive torsion in front of the polymerase induces supercoiling (writhe) and is largely resolved by Top2. Negative torsion behind the polymerase induces DNA strand separation and is largely resolved by Top1.[Top1, Top2] (Mus musculus) PubMed

 7317.

Ash1 recognition by Cdc4 appears to be mediated by at least three phosphorylation sites that form two redundant diphosphorylated degrons.[Cdc4, Ash1] (Mus musculus) PubMed

 7318.

Spt6 regulates transcription by controlling chromatin structure over regulatory regions.[Spt6] (Mus musculus) PubMed

 7319.

Sen1 prevents the accumulation of R loop formations and protects the genome from instability. (Mus musculus) PubMed

 7320.

Cdc48 functions in conjunction with proteasomes to sustain processive degradation of unstable subunits of some macromolecular protein complexes. (Mus musculus) PubMed

 7321.

Mutants lacking functional addB(HP1089} or addA show deficiency in intrachromosomal RecA-dependent homologous recombination. [AddA] (Mus musculus) PubMed

 7322.

Ctr2 mutant displayed sensitivity to copper starvation and defects in polysaccharide capsule production and increased phagocytosis. [Ctr2] (Mus musculus) PubMed

 7323.

Deletion and overexpression of flbE result in developmental defects.[FlbE] (Mus musculus) PubMed

 7324.

hydrolysis of p-nitrophenyl-beta-1,4-cellobioside (pNP-G2) by the catalytic domain of the retaining-family 5-2 endocellulase Cel5A from Thermobifida fusca [Cel5Acd] (Mus musculus) PubMed

 7325.

Deletion and overexpression of flbE result in developmental defects.[FlbE] (Mus musculus) PubMed

 7326.

flbB encodes two basic leucine zipper domain (bZIP) proteins required for proper asexual development and gliotoxin production (flbB) (Mus musculus) PubMed

 7327.

Thus, AcuM represses SreA and thereby induces iron acquisition, a process that is essential for the maximal virulence of Aspergillus fumigatus.[AcuM & SreA] (Mus musculus) PubMed

 7328.

Mass spectrometry analysis identified the the 47-kDa protein as the putative chlorophenol reductive dehalogenase CprA3.[CprA3] (Mus musculus) PubMed

 7329.

DSM2 contributes to control of the xanthophyll cycle and ABA synthesis, both of which play critical roles in the establishment of drought resistance in rice. [DSM2] (Mus musculus) PubMed

 7330.

Genetic analysis determined a single recessive gene controls male sterility in Guangzhan63S variety of rice. [ptgms2-1] (Mus musculus) PubMed

 7331.

The 108N, 51I and 437G mutations prevail in the populations of P. falciparum, indicating a cumulative effect of mutations (Mus musculus) PubMed

 7332.

Pot1 and Rqh1 are required for efficient chromosome segregation.[Pot1, Rqh1] (Mus musculus) PubMed

 7333.

Mre11 nuclease activity and Ctp1 are critical for efficient Rad3-to-Chk1 signaling.[Mre11, Ctp1, Chk1, Rad3, Tel1] (Mus musculus) PubMed

 7334.

The histone complex containing Asf1 and HIRA has a role in global histone deacetylation and transcriptional silencing. [2 genes] (Mus musculus) PubMed

 7335.

Interaction between two chromodomains (CD) causes Swi6 to tetramerize on a nucleosome, generating two vacant CD sticky ends. (Mus musculus) PubMed

 7336.

levels of IR2 and IR3 mRNA declined from pre-hatch (29 days post-fertilization, dpf) to post-hatch (68-90 dpf), whereas levels of IR1 and IR4 remained relatively unchanged[insulin receptor] (Mus musculus) PubMed

 7337.

The recessive lss mutation reduces expression of the SUNN gene. [SUNN] (Mus musculus) PubMed

 7338.

2-keto-3-deoxy-D-manno-octulosonic acid (Kdo) cleavage requires simultaneous expression of both proteins KdoH1 and KdoH2.[KdoH1 and KdoH2] (Mus musculus) PubMed

 7339.

Together, these results suggest a role for the Nik system in the urinary tract infection by S. aureus, probably due to the urease-mediated pH increase of the urine.[NikA & NikBCDE] (Mus musculus) PubMed

 7340.

TBT-bp(alpha) is a tributyltin binding protein (Mus musculus) PubMed

 7341.

OsDRP2B is a typical dynamin-related protein-2 family member. Mutants have lower cellulose content and altered cell wall composition. [OsDRP2B] (Mus musculus) PubMed

 7342.

OsMPK6 regulates systemic acquired resistance in response to Xanthomonas oryzae infection. [OsMPK6] (Mus musculus) PubMed

 7343.

The activity of UreA is down-regulated post-translationally by ammonium-promoted endocytosis. [UreA] (Mus musculus) PubMed

 7344.

Data show that BcsK(C)/BcsL(B) interaction is essential for the T6SS activity in B. cenocepacia K56-2: [BcsK(C) and BcsL(B)] (Mus musculus) PubMed

 7345.

Crystal structure of RNAP bound to Gfh1: results reveal that Gfh1 inhibits transcription by preventing NTP binding and freezing RNAP in the alternative structural state [Gfh1] (Mus musculus) PubMed

 7346.

VefA is essential for excision. [VefA] (Mus musculus) PubMed

 7347.

Mutations at the pore-helix position Glu71 of KcsA unmask a series of kinetically distinct modes of gating in a side chain-specific way. [KcsA] (Mus musculus) PubMed

 7348.

Substrates are recruited to the Anaphase-promoting complex by binding to a bipartite substrate receptor composed of Cdh1 and Doc1. [2 genes - Cdh1, Doc1] (Mus musculus) PubMed

 7349.

Dcr1 physically associates with some euchromatic genes, noncoding RNA genes and retrotransposon long terminal repeats, and that this association is independent of the Clr4 histone methyltransferase. (Mus musculus) PubMed

 7350.

phoPQ mutants were more resistant to strong acidic conditions (pH 4.5 or 5) than that of the wild-type (WT) strain, suggesting that this system in Erwinia amylovora may negatively regulate acid resistance gene expression.[PhoPQ] (Mus musculus) PubMed

 7351.

Data demonstrate that miR-275 is indispensable for blood-meal-activated processes: [miR-275] (Mus musculus) PubMed

 7352.

The dynamics of matefin/SUN-1 aggregates remained unchanged throughout leptonene/zygotene, despite the progression of pairing.[KASH] (Mus musculus) PubMed

 7353.

This study defines a new regulator, CHB-3, in the trafficking process and also shows the importance of ciliary targeting of the signaling molecule, GCY-12, in sensory-dependent body size regulation in C. elegans.[CBH-3, GCY-12] (Mus musculus) PubMed

 7354.

SIC (streptococcal inhibitor of complement) interferes with the activation of the contact system and blocks the activity of antibacterial peptides generated through complement and contact activation [SIC] (Mus musculus) PubMed

 7355.

The ability of Escherichia coli K-12 MG1655 to overcome the loss of phosphoglucose isomerase (pgi) by adaptively evolving ten replicates of E. coli lacking pgi, was investigated.[Pgi] (Mus musculus) PubMed

 7356.

We demonstrate through sequence and structural comparisons that HugZ belongs to a new heme-binding protein family with a split-barrel fold[HUGZ] (Mus musculus) PubMed

 7357.

Atg9 has all the prerequisites to be a major factor in regulating the supply of at least part of the membranes necessary for the formation and expansion of nascent autophagosomes.[Atg9] (Mus musculus) PubMed

 7358.

GAP40 is a polytopic inner membrane complex protein that belongs to the glideosome. [GAP40] (Mus musculus) PubMed

 7359.

DAF-25 is required for proper DAF-11 ciliary localization.[DAF-25, DAF11] (Mus musculus) PubMed

 7360.

These studies pinpoint RACK-1 as a component of a novel signaling pathway involving Rac GTPases and UNC-115/abLIM.[UNC-115, CED-10] (Mus musculus) PubMed

 7361.

A marker at the 5' untranslated region of the GARS-AIRS-GART gene was significant for inosine 5'-monophosphate content (GARS-AIRS-GART). (Mus musculus) PubMed

 7362.

Analysis of the mVbeta8.2-SEG interface allowed us to explain the higher affinity of this complex compared with the others, which may account for the early activation of T-cells bearing mVbeta8.2 by SEG[SEG] (Mus musculus) PubMed

 7363.

Phosphorylation of Atg1 on multiple sites provides critical mechanisms to regulate Atg1 function in autophagy and the Cvt pathway.[Atg1] (Mus musculus) PubMed

 7364.

RACK1 stimulates the translation arrest that is induced by basic amino-acid sequences that leads to endonucleolytic cleavage of the mRNA, as well as to co-translational protein degradation.[RACK1] (Mus musculus) PubMed

 7365.

These data suggest a model wherein Dpb3 and Dpb4 do not directly influence replication fidelity per se, but rather contribute to normal replication fork progression.[Dpb3, Dpb4] (Mus musculus) PubMed

 7366.

gp41 may destabilize viral membrane, priming the virus for fusion with a target cell.[gp41] (Mus musculus) PubMed

 7367.

The results indicate that the nucleocapsid locally melts the TAR RNA and RRE-IIB RNA hairpins, whereas Tat and Rev may strengthen the hairpin structures through specific binding interactions.[Nucleocapsid] (Mus musculus) PubMed

 7368.

The conformational change of adenylate kinase (AK) between open and closed forms by conducting five all-atom molecular-dynamics simulations, each of 100 ns duration, was studied.[Adenylate kinase] (Mus musculus) PubMed

 7369.

Data show that Im7 glycosylation influences folding by modulating the local conformational preferences of the glycosylated sequence: [Im7] (Mus musculus) PubMed

 7370.

Results show that rhcmvIL-10 alters the earliest host responses to viral antigens by dampening the magnitude and specificity of innate effector cells to primary RhCMV infection: [rhcmvIL-10; UL111A] (Mus musculus) PubMed

 7371.

study reports that rice cells require a LysM receptor-like kinase, OsCERK1, in addition to CEBiP, for chitin signaling[CEBiP] [CERK1] (Mus musculus) PubMed

 7372.

identified mutations in both the gyrA and parC genes of four ofloxacin- and ciprofloxacin-resistant S. pneumoniae isolates; mutations were found in the gyrA gene at positions Ser81Phe, Glu85Gly, Glu85Lys and in the parC gene at Ser79Tyr [gyrA and parC] (Mus musculus) PubMed

 7373.

Combined resistance to lincosamides, pleuromutilins and streptogramin A antibiotics is associated with the resistance genes vga(A)5 and vga(C), both of which are located on plasmids in MRSA from swine. [vga(A)] (Mus musculus) PubMed

 7374.

Data show, by performing site-directed mutagenesis of chimeric chicken alpha7/mouse 5-hydroxytryptamine 3 receptor-channel complex, that the allosterically potentiating ligand binding site is different from the positive allosteric modulators binding site. (Mus musculus) PubMed

 7375.

The relative position between the highly conserved GXXXG motif and an arginine residue around the gp41 MSD alpha-helix is critical for intracellular trafficking of HIV-1 Env. [gp41] (Mus musculus) PubMed

 7376.

ATM and ATR homologes(ataxia telangiestasia muted proteins) of Neurospora crassa regulate independent pathways and are essential for normal cell growth and maintenance of chromosome integrity. [ATM][ATR] (Mus musculus) PubMed

 7377.

study of the transcription of BM109, characterized its structural localization and the protein expression pattern [Nm109] (Mus musculus) PubMed

 7378.

Mutation of the ZEBRA2 gene results in the accumulation of all-trans-lycopene precursor, prolycopene (7Z,9Z,7'Z,9'Z tetra cis-lycopene), in dark-grown zebra2 tissues[ZEBRA2] (Mus musculus) PubMed

 7379.

no consistent relationship between growth rate and resistance phenotypes among the DHFR alleles [DHFR] (Mus musculus) PubMed

 7380.

In combination with the overproduction of the chromosomal AmpC enzyme, the loss of OmpF may have played a role in the acquisition of meropenem resistance. [AmpC] (Mus musculus) PubMed

 7381.

GacA regulates the virulence in an iron-dependent manner. [GacA] (Mus musculus) PubMed

 7382.

CcrAB genes are expressed in E. faecium and are widely distributed in the other Enterococcus. [CcrAB] (Mus musculus) PubMed

 7383.

FSY1 was repressed by high concentrations of glucose or fructose and was highly expressed on ethanol as the sole carbon source. [FSY1] (Mus musculus) PubMed

 7384.

Myb-4controls a hierarchical network comprised of several regulatory sub-clusters associated with cellular defense and rescue, metabolism and development [OsMyb4] (Mus musculus) PubMed

 7385.

the identification of a novel conjugative plasmid carrying the cfr gene indicates the ability of cfr to spread to other MRSA strains [cfr] (Mus musculus) PubMed

 7386.

Both NP and PB2 contribute to the high pathogenicity of the H5N1 HPAI viruses in chickens, and valine at position 105 of NP may be one of the determinants for adaptation of avian influenza viruses from ducks to chickens. [NP, PB2] (Mus musculus) PubMed

 7387.

YshA is an unknown outer-membrane protein from Salmonella typhimurium [YshA] (Mus musculus) PubMed

 7388.

Unitary conductance, dwell times, and open probability of the K(+) channel KcsA as a function of temperature in lipid bilayers were measured.[KcsA] (Mus musculus) PubMed

 7389.

NatB deletion led to a very significant change in protein phosphorylation.[NatB] (Mus musculus) PubMed

 7390.

These results indicate that post-transcriptional control is important in the myo1Delta stress response and possibly other stresses in yeast.[Myo1] (Mus musculus) PubMed

 7391.

All rate constants for the multistep reaction between EF-Tu (wild-type and two mutants), EF-Ts, GDP, and GTP were determined using the stopped-flow technique.[EF-Tu] (Mus musculus) PubMed

 7392.

the co-crystal structure of the CusBA efflux complex, showing that the transporter (or pump) CusA, which is present as a trimer, interacts with six CusB protomers and that the periplasmic domain of CusA is involved in these interactions [CusA & CusB] (Mus musculus) PubMed

 7393.

The linker of the Trichoderma reesei Family 7 cellobiohydrolase (Cel7A) is examined by simulation.[Cel7A] (Mus musculus) PubMed

 7394.

B. mori 3-dehydroecdysone 3beta-reductase (3DE 3beta-reductase) maintains ecdysone titer through converting 3DE to ecdysone. [3-dehydroecdysone 3beta-reductase/3DE 3beta-reductase] (Mus musculus) PubMed

 7395.

Charged residues in the cytoplasmic loop of MotA are required for assembly of the flagellar motor. {motA] (Mus musculus) PubMed

 7396.

V. cholerae mutant lacking TarA is compromised for mouse colonization. [TarA] (Mus musculus) PubMed

 7397.

NleH1 or nleH2 decreased IKK-beta-induced NF-kappaB activity and attenuated TNF-alpha-induced degradation of phospho-IkappaBalpha. [NleH1 and NleH] (Mus musculus) PubMed

 7398.

This investigation shows that minor capsid proteins, BDLF1 and BORF1, form a triplex similar to that of HSV-1, which interacts with VCA to connect capsomers on a capsid. {BDLF1, BORF1] (Mus musculus) PubMed

 7399.

Reported here is the gp23.1 crystal structure at 1.6 A resolution, a protein that lacks sequence identity to any known protein. [gp23.1] (Mus musculus) PubMed

 7400.

The Snf7 binds Bro1 domain enhances the stability of ESCRT-III by inhibiting Vps4-mediated disassembly in vivo and in vitro. [Bro1 & Snf7] (Mus musculus) PubMed

 7401.

The first thermodynamic study on the conformational equilibrium and stability of NS3 and the effect of zinc on such equilibrium is presented here.[NS3] (Mus musculus) PubMed

 7402.

The product of the rssC gene is predicted to be mainly responsible for fatty-acid biosynthesis of the Serratia marcescens outer membrane.[rssC] (Mus musculus) PubMed

 7403.

Deletion of ptkA had a lethal effect in later stages of vegetative growth and completely impeded asexual development. [ptkA] (Mus musculus) PubMed

 7404.

Detailed kinetic analysis using 3'-labeled DNA indicates that endonuclease V also possesses non-specific 5'-exonuclease activity (endonuclease V) (Mus musculus) PubMed

 7405.

Overexpression of rsmA restores production of sterigmatocystin. [rsmA] (Mus musculus) PubMed

 7406.

The DR7B protein bound to human p53 protein. p105-p50/p65 mRNA expression and activation of the NFkappaB complex were increased when DR7B was expressed.(HHV-6 DR7B protein) (Mus musculus) PubMed

 7407.

HI assays against H1N1pdm demonstrate that the D131E and S186P mutations caused minor antigenic changes and, likely, affected receptor binding.[Hemagglutinin;A/California/04/09(H1N1)] (Mus musculus) PubMed

 7408.

findings support a model in which PrrC toxicity is contingent on head-to-tail dimerization of the NTPase domains to form two composite NTP phosphohydrolase sites (PrrC). (Mus musculus) PubMed

 7409.

nsrR mutant constitutively overexpresses Hmp is hypersensitive to peroxynitrite. [Hmp] (Mus musculus) PubMed

 7410.

OsMADS6 is highly expressed in flower and endosperm; study shows that H3K27 is trimethylated in tissues where OsMADS6 is silenced, and that H3K36 is trimethylated in tissues where OsMADS6 is highly activated. [MADS6] (Mus musculus) PubMed

 7411.

His160 and Asn191 were found to be essential for catalysis and Asn182 to be required for stability of EndA (EndA). (Mus musculus) PubMed

 7412.

Data show that replacement of Tyr253 by alanine in alternative oxidase (AOX) resulted in a 72% loss of activity suggesting that the benzoquinone group and not hydroxyl group is important for quinol binding: [AOX] (Mus musculus) PubMed

 7413.

A structure determination for the monomeric form using traditional NMR methods is presented, followed by a dimer structure determination using docking under orientation constraints from residual dipolar couplings data. (Mus musculus) PubMed

 7414.

Fet3 protein lacking any one of the core glycan units is found in an intracellular high-molecular mass species resolvable by blue native gel electrophoresis. [Fet3] (Mus musculus) PubMed

 7415.

Transcription factor genes YAP1, PDR1, PDR3, RPN4, and HSF1 appeared to play key regulatory rules for global adaptation in the yeast S. cerevisiae.[YAP1, PDR1, PDR3, RPN4, HSF1] (Mus musculus) PubMed

 7416.

Expression of hbz resulted in lower levels of p30(II) mRNA.[hbz & p30II] (Mus musculus) PubMed

 7417.

RcsB protein represses rcsD gene expression by binding directly to the P promoter, negatively autoregulating the RcsCDB system. [RcsD] (Mus musculus) PubMed

 7418.

KU70 homologue (NkuA) and the heterochromatin-associated proteins HepA, ClrD and HdaA were partially required for transgene silencing. [NkuA] (Mus musculus) PubMed

 7419.

zinc finger structure and pol eta regulation [polymerase eta] (Mus musculus) PubMed

 7420.

The SunB is essential for accurate prestalk/prespore differentiation during Dictyostelium development and that its cell-type dependent localization is regulated by a Dd-STATa-mediated signaling pathway.(SunB protein) (Mus musculus) PubMed

 7421.

Taken together, these results indicate that CYP51A is required for efficient conidiogenesis, full virulence and for mediating DMI sensitivity by the rice blast fungus.[CYP51A] (Mus musculus) PubMed

 7422.

The interaction of streptococcal pyrogenic exotoxin B (SpeB) with alpha 1-antitrypsin in vitro and its effects in a mouse model of systemic infection are reported.[SpeB] (Mus musculus) PubMed

 7423.

The results suggest that the position of the prion domain affects the ability of Ure2 to form fibrils primarily due to effects on its flexibility.[Ure2] (Mus musculus) PubMed

 7424.

Different non-structural protein 1 (NS1) of influenza viruses, one from allele A (H10N4) and another from allele B(H10N7), show different abilities to suppress the type I interferon beta expression. (Mus musculus) PubMed

 7425.

pathogenicity test for E058 strain and E058 (delta aes-31) strain showed that the mutant had a higher mortality (75%) to 35-day-old specific pathogen-free (SPF) chicks than that of E058 (62.5%)[ aes-31 ] (Mus musculus) PubMed

 7426.

This work reveals Ustilago maydis Rco1 as the first eukaryotic resveratrol cleavage enzyme identified so far.[Rco1] (Mus musculus) PubMed

 7427.

[2-KPCC, 2-ketopropyl CoM oxidoreductase (carboxylating), EC 1.2.7.-] crystal structure of 2-KPCC at 1.9 A resolution; structure with substrates/ligands bound (CO2, 2-ketopropyl CoM); catalytic mechanisms discussed (Mus musculus) PubMed

 7428.

[GcpE, hydroxymethylbutenyl 4-diphosphate synthase] X-ray structure at 2.5 A resolution; putative substrate binding site; binding mode of [4Fe-4S] cluster; catalytic mechanisms discussed (Mus musculus) PubMed

 7429.

Inactivation of PI3K enhances Legionella infection and suppresses the protective effect of Nramp1 overexpression. [ Nramp1 ] (Mus musculus) PubMed

 7430.

Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner. [Atg8] (Mus musculus) PubMed

 7431.

Abch1 is a novel ATP binding cassette (ABC) transporter found in fish. This study is an initial characterisation of this transporter using phylogenetic analyses, membrane topology prediction and determination of tissue expression pattern in zebrafish (Mus musculus) PubMed

 7432.

present complete MRP1 (ABCC1) and partial MRP3 (ABCC3) cDNAs from rainbow trout (Oncorhynchus mykiss). [ABCC1 protein] (Mus musculus) PubMed

 7433.

The concerted activity of p8 and p12 is essential for the persistence of virus infected cells in the host.[p8, p12] (Mus musculus) PubMed

 7434.

The gat1 mutant exhibited impaired growth on all amino acids tested as sole nitrogen sources, with the exception of arginine and proline.[GAT1] (Mus musculus) PubMed

 7435.

The data suggest that three different Aedes aegypti midgut proteins, i.e., cadherin, AaeALP1, and AaeAPN1, are involved in Cry11Ba binding to Aedes aegypti midgut brush border membranes.[AaeALP1] (Mus musculus) PubMed

 7436.

This study study demonstrated that the lipid kinase Vps34p is already associated with peroxisomes during biogenesis.[Vps34p] (Mus musculus) PubMed

 7437.

DOT1A dimethylated H3K79, DOT1B trimethylated H3K79 even in the absence of dimethylation by DOT1A. [DOT1A, DOT1B] (Mus musculus) PubMed

 7438.

The authors show that an anti-sigma factor antagonist BldG associates with RshA and negatively regulates its activity.[BldG] (Mus musculus) PubMed

 7439.

Rsr1 also exhibits heterotypic interaction with the Cdc42 GTPase in vivo.[Rsr1, Cdc42] (Mus musculus) PubMed

 7440.

The translational regulation of the most highly osmostress-regulated mRNAs was more strongly dependent on the stress-activated protein kinases Hog1 and Rck2 than the transcriptional regulation.[Hog1] (Mus musculus) PubMed

 7441.

REVIEW for HTLV-I p30 (Mus musculus) PubMed

 7442.

The cell-surface lipoprotein SiaA, a component of the SiaABC transporter, acts as the primary receptor for heme in the infamous human pathogen Streptococcus pyogenes. (Mus musculus) PubMed

 7443.

The purified Rvs161-Rvs167 complex binds to liposomes in a curvature-independent manner and promotes tubule formation in vitro.[Rvs161, Rvs167] (Mus musculus) PubMed

 7444.

The complex functions of HBZ modulate T-cells, and promote their proliferation, which is likely indispensable for leukemogenesis by HTLV-1.[HBZ] (Mus musculus) PubMed

 7445.

The splicing activity of the PRP8 intein from the Blastomyces dermatitidis, Emmonsia parva and Paracoccidioides brasiliensis species complex was demonstrated in a non-native protein context in Escherichia coli. (Mus musculus) PubMed

 7446.

UspB, a member of the RpoS regulon, is required for proper DNA repair [UspB][RuvC][RpoS] (Mus musculus) PubMed

 7447.

These results indicate that different sterol demethylation inhibitor fungicides target different CYP51 proteins in Fusarium graminearum and that a mixture of fungicides can result in synergistic effects.[CYP51] (Mus musculus) PubMed

 7448.

In conclusion, the Ste50 adaptor protein controls sexual differentiation of Cryptococcus neoformans via the pheromone-responsive MAPK pathway but is not required for virulence.[Ste50] (Mus musculus) PubMed

 7449.

Data show that CENH3 expression patterns shed more light on the inter-coordination between varied centromeric DNA sequences and highly conserved kinetochore protein in synthesized allopolyploids of Oryza: [CENH3] (Mus musculus) PubMed

 7450.

The authors propose a K(+)-H(+) symporter that, under certain conditions may work as a K(+)-Na(+) transporter, as the mechanism driving K(+) influx mediated by DhHak1p.[Hak1] (Mus musculus) PubMed

 7451.

A short conserved C-terminal sequence in Mto1, termed MASC, is important for targeting Mto1 to multiple distinct microtubule organizing centers (MTOCs). (Mus musculus) PubMed

 7452.

The present review is focused on the current knowledge of p13, an HTLV-1 accessory protein targeted to the inner mitochondrial membrane and, under certain conditions, to the nucleus.[p13] (Mus musculus) PubMed

 7453.

This work defines a new role for arrestins in membrane trafficking and offers insight into how alpha-arrestins coordinate signaling events with protein trafficking.[Aly1, Aly2] (Mus musculus) PubMed

 7454.

SifA may use a similar mode of action via Rho proteins to alter yeast peroxisomal and mammalian endosomal membranes. [Rho1] (Mus musculus) PubMed

 7455.

ROS production by mitochondrial mutants and found that isp-1 and nuo-6 mutants have increased generation of the superoxide anion but not increased levels of other ROS and that this increase is necessary and sufficient for longevity.[Nuo-6] (Mus musculus) PubMed

 7456.

(photoactivated adenylyl cyclase alpha; PACalpha) PACalpha is expressed in cholinergic neurons and is used to determine changes in neurotransmitter release and behavioral effects. (Mus musculus) PubMed

 7457.

Hsp33 crystal structure was determined at 2.40A resolution.[Hsp33] (Mus musculus) PubMed

 7458.

The crystal structure of pyridoxal phosphate-bound SpeA from Campylobacter jejuni is reported at 3.0A resolution and that of Escherichia coli SpeA in complex with a sulfate ion is reported at 3.1A resolution.[SpeA] (Mus musculus) PubMed

 7459.

The crystallographic structures of BamC, BamD and BamE, each lacking the N-terminal membrane anchor, are described.[BamC, BamD, BamE] (Mus musculus) PubMed

 7460.

Crystals of C-terminally His6-tagged Wzi diffracted to 2.8A resolution.[Wzi] (Mus musculus) PubMed

 7461.

During synthesis of siderophore enterobactin in iron-starved strain BW25113 cells, tetrameric EntA optimally interacts with EntE forming a specific complex with EntE, resulting in an enhancement of EntE activity. [EntA] (Mus musculus) PubMed

 7462.

Rice MEL2 protein discovered in this study shows partial similarity with human proline-rich RRM protein, deleted in Azoospermia-Associated Protein1 (DAZAP1), though MEL2 also possesses ankyrin repeats and a RING finger motif[MEL2] (Mus musculus) PubMed

 7463.

The crystal structure of pyridoxal phosphate-bound SpeA from Campylobacter jejuni is reported at 3.0A resolution and that of Escherichia coli SpeA in complex with a sulfate ion is reported at 3.1A resolution.[SpeA] (Mus musculus) PubMed

 7464.

find that Clr5 controls gene expression at multiple chromosomal locations in addition to affecting the mating-type region[Clr5 ] (Mus musculus) PubMed

 7465.

BoNT/D receptor binding domain was crystallized and the crystals diffracted to 1.65A resolution.[BoNT/D] (Mus musculus) PubMed

 7466.

three-dimensional crystal structures of SgrAI bound to cleaved primary-site DNA and Mg(2)(+) and bound to secondary-site DNA with either Mg(2)(+) or Ca(2)(+) are presented[SgrAI ] (Mus musculus) PubMed

 7467.

Virulent T. gondii strain ROP18 kinase phosphorylates host Irga6 at two threonines in the nucleotide-binding domain, biochemically inactivating the GTPase and inhibiting its accumulation and action at the T. gondii parasitophorous vacuole membrane.[ROP18] (Mus musculus) PubMed

 7468.

VacA induces apoptosis mediated by BAX and BAK but additionally induces the translocation of BAX to mitochondrial endosomes[VacA induces apoptosis mediated by BAX and BAK but additionally induces the translocation of BAX to mitochondrial endosomes [VacA] (Mus musculus) PubMed

 7469.

Data show that the OsMKK4-OsMPK6 cascade plays a crucial role in reprogramming plant metabolism during MAMP-triggered defense responses: [OsMKK4 & OsMPK6] (Mus musculus) PubMed

 7470.

the GH57 GBE possesses about 4% hydrolytic activity with amylose and in vitro forms a glucan product with a novel fine structure, demonstrating that the GH57 GBE is clearly different from the GH13 GBEs characterized to date. [GH57 GBE] (Mus musculus) PubMed

 7471.

Two LjCLE genes, LjCLE19 and 20, were up-regulated specifically and greatly in roots of L. japonicus by phosphate addition to the hydroponic solution.[LjCLE19,LjCLE20] (Mus musculus) PubMed

 7472.

These results illustrate that over-expression of osa-MIR393 can negatively regulate rice salt-alkali stress tolerance.[osa-MIR393] (Mus musculus) PubMed

 7473.

Interferon tau induces expression of DEAD box polypeptide 58 (DDX58) and phospholipid scramblase 1 (PLSCR1) in ovine endometrial cells via the classical STAT1-mediated cell signaling pathway. (Mus musculus) PubMed

 7474.

Both Lgl and Dsh are required for normal apical-basal polarity of Xenopus ectodermal cells. (Mus musculus) PubMed

 7475.

CHAT-1 and TAT-1 maintain membrane phosphatidylserine asymmetry, thus promoting membrane tubulation and regulating endocytic sorting and recycling. [CHAT1] (Mus musculus) PubMed

 7476.

Study reports the crystal structure of a UvrA protein in complex with a chemically modified oligonucleotide; shows that the UvrA dimer does not contact the site of lesion directly, but rather binds the DNA regions on both sides of the modification.[UvrA] (Mus musculus) PubMed

 7477.

Formation of the outer membrane translocon for cellular import of the nuclease colicins is a demonstrably dynamic process, because it depends on lateral diffusion of BtuB and collisional interaction with relatively immobile OmpF.[BtuB, OmpF] (Mus musculus) PubMed

 7478.

LaeA control fungal morphological, chemical development, and interactions of the velvet regulators. [LaeA] (Mus musculus) PubMed

 7479.

OsRAN2 regulats cold resistance in rice by maintaining cell division through promoting the normal export of intranuclear tubulin at the end of mitosis. (Mus musculus) PubMed

 7480.

OsRab5a plays an essential role in trafficking of storage protein to protein body II. [OsRab5a] (Mus musculus) PubMed

 7481.

crystal structure of Hbp shows that the protein carries a serine protease domain and a small domain of 75 residues which is inserted into the long beta-helix characteristic of autotransporter passenger proteins[Hbp/Tsh, UniProt reference code O88093] (Mus musculus) PubMed

 7482.

Certain TaGS2 haplotypes may be valuable in breeding wheat varieties with improved agronomic performance and Nitrogen-use efficiency.[Ta-GS2] (Mus musculus) PubMed

 7483.

A major BiP cochaperone in antibody folding, ERdj3, modulated the conformational space of BiP in a nucleotide-dependent manner, placing the lid subdomain in an open, protein-accepting state.[ERdj3] (Mus musculus) PubMed

 7484.

Interferon tau stimulated expression of N-myc interactor gene mRNA in 2fTGH (ie, in a STAT1-dependent manner), but not in U3A (STAT1-null) cells.[N-myc interactor gene, IFN tau] (Mus musculus) PubMed

 7485.

The substrate cleavage pattern monitored by capillary zone electrophoresis showed that TpAraF is a classical exo-acting enzyme producing arabinose as its end-product.[AraF] (Mus musculus) PubMed

 7486.

[Isc1, inositol phospho-sphingolipid-phospholipase C 1] Isc1 exhibits only IPC-PLC activity (not SM-PLC as seen in homologous enzymes in other species). Isc1 regulates metabolism/accumulation of complex sphingolipids and ceramides. (Mus musculus) PubMed

 7487.

[Isc1, inositol phospho-sphingolipid-phospholipase C 1] Isc1 exhibits only IPC-PLC activity (not SM-PLC as seen in homologous enzymes in other species). (Mus musculus) PubMed

 7488.

INTERMEDIUM-C, a modifier of lateral spikelet fertility in barley, is an ortholog of the maize domestication gene TEOSINTE BRANCHED 1 [TEOSINTE BRANCHED 1] (Mus musculus) PubMed

 7489.

Despite overall similarity of Xenotropic MuLV-related virus VP62 protease to other retropepsins, the topology of its dimer interface more closely resembles those of the monomeric, pepsin-like enzymes.[protease] (Mus musculus) PubMed

 7490.

Variation in SsIIa enzyme activity is associated with the cohesiveness of rice grains when cooked.[SsIIa] (Mus musculus) PubMed

 7491.

Our observations confirm that in contrast to its homologues in other organisms, Mip1 can function as a single-subunit replicative polymerase. [Mip1] (Mus musculus) PubMed

 7492.

Sumoylation of T. brucei Topoisomerase-II alpha is not required for centromere-specific cleavage activity (Topoisomerase-II alpha). (Mus musculus) PubMed

 7493.

Substance P and CGRP correlate with the occurrence and development of allergic rhinitis. [Substance P] (Mus musculus) PubMed

 7494.

The authors found that simultaneous mutations at three positions (E67S/E74S/E75S) of NS2/NEP were important for inhibition of influenza viral polymerase activity.[NS2] (Mus musculus) PubMed

 7495.

The study describes the analysis of the folding behavior of 12 different alanine-scanning mutants of DsbB. [DsbB] (Mus musculus) PubMed

 7496.

The authors found that insertions of as many as twenty residues after the twelfth residue of murine leukemia virus nucleocapsid yielded proteins that directed the efficient assembly of virus particles.[nucleocapsid] (Mus musculus) PubMed

 7497.

Gene disruption established that Dur3, encoded by orf 19.781, is the predominant urea transporter.[Dur3] (Mus musculus) PubMed

 7498.

Lupeol synthase, encoded by OSC3, and its product, lupeol, have a role in developing roots and nodules in Lotus japonicus. (Mus musculus) PubMed

 7499.

Depolarization of GlyCl-expressing cells induces these drastic changes in melanocyte behavior via a serotonin-transporter-dependent increase of extracellular serotonin (Mus musculus) PubMed

 7500.

CHLalphaGcT is originally synthesized in the cytoplasm of H. pylori as an inactive form and then activated when it is associated with the cell membrane [cholesterol alpha-glucosyltransferase] (Mus musculus) PubMed

 7501.

Changes in extracellular pH result in altered transcription of BTN1.[Btn1] (Mus musculus) PubMed

 7502.

These findings suggest that the movement of broad bean wilt virus 2 between cells is mediated by the tubular structures that contain the VP37 protein, and the VP37 protein itself is capable of inducing these tubule-like structures in cells.[VP37] (Mus musculus) PubMed

 7503.

One gene encodes a UDP-xylose synthase (Uxs) that converts UDP-glucuronic acid to UDP-xylose, and the second encodes a UDP-xylose 4-epimerase (Uxe) that interconverts UDP-xylose and UDP-arabinose.[Uxs & Uxe] (Mus musculus) PubMed

 7504.

While characterizing the cDNAs, fortuitous mutations at NS2A position 46 and NS5 position 836 were found to affect viral production.[NS2A & NS5] (Mus musculus) PubMed

 7505.

Several backcross derivatives (hexaploid) possessing variable sized Sr22-carrying segments were used in this study to identify a closely linked DNA marker. [Sr22] (Mus musculus) PubMed

 7506.

TaGW2 was located in homologous group 6 chromosomes.[TaGW2] (Mus musculus) PubMed

 7507.

The slow-rusting gene(s) Lr67/Yr46 can be utilized in combination with other slow-rusting genes to develop high levels of durable adult plant resistance to leaf rust and stripe rust in wheat.[Lr67, Yr46] (Mus musculus) PubMed

 7508.

Entamoeba histolytica holotransferrin-binding protein was identified by MS/MS analysis and database searches as acetaldehyde/alcohol dehydrogenase-2 (EhADH2), an iron-dependent enzyme.[ADH2] (Mus musculus) PubMed

 7509.

OsHMA3 was identified as the gene that controls root-to-shoot cadmium translocation rates. (Mus musculus) PubMed

 7510.

NCC (Slc12a3)is highly expressed in the mefugu kidney but at lower levels in the torafugu kidney. NKCC2 (Slc12a1) is highly expressed in the kidney of mefugu and torafugu. (Slc12a1 and Slc12a3) (Mus musculus) PubMed

 7511.

Nuclear magnetic resonance techniques allowed the calculation of the structure of the LytA197-210[ND] peptide, which displayed a beta-hairpin conformation highly similar to that found within the full-length C-LytA module. [LytA] (Mus musculus) PubMed

 7512.

Analyzed are the stability and folding of yeast hexokinase isoenzyme ScHxk2 consisting of two domains with a discontinuous peptide sequence. [ScHxk2] (Mus musculus) PubMed

 7513.

Deletion of residues 151-158 accelerates the nucleation, growth and fragmentation of amyloid-like aggregates in vitro, and the aggregates formed are able to seed formation of fibrils of the wild-type protein.[Ure2] (Mus musculus) PubMed

 7514.

Collectively, this finding suggests that S186 at the N terminal region of PA of swine-origin influenza virus H1N1 is necessary for the protein to function optimally.[PA] (Mus musculus) PubMed

 7515.

The membrane-association of PfYkt6.1 was dependent on the presence of a conserved C-terminal CAAX motif (CCSIM).[Ykt6.1] (Mus musculus) PubMed

 7516.

Capsid protein could interact with the nuclear import factor importin alpha, suggesting that the CP is possibly imported into the nucleus via an importin alpha-dependent pathway.[capsid protein] (Mus musculus) PubMed

 7517.

inactivation and initial interrogation of key oxygenase CmmOIV of the biosynthetic pathway of chromomycin A(3) in Streptomyces griseus ssp. griseus [CmmOIV] (Mus musculus) PubMed

 7518.

In this study the authors identified TAF250, an RNA polymerase II complex component, as an essential gene.[TAF250] (Mus musculus) PubMed

 7519.

Research into basic-rich sequences that could be indicative of a functional nuclear localization signal led to the identification of a novel nuclear localization signal for TgGCN5-B, RPAENKKRGR.[GCN5-B] (Mus musculus) PubMed

 7520.

The data presented here show that NikR may first select its targets by identifying sequences within the previously defined consensus and subsequently establish base-specific contacts to firmly bind DNA, in particular with the fecA3 target.[NikR; fecA3] (Mus musculus) PubMed

 7521.

Results describe a molecular switch governing TSHbeta transcription through the circadian clock, linking the circadian clock to the evolution of seasonal timing in mammals [TSHbeta]. (Mus musculus) PubMed

 7522.

DPV022 encoded an inhibitor of apoptosis and interacted with cellular Bak and Bax. [DPV022] (Mus musculus) PubMed

 7523.

crystal structure of a TrkH; results reveal the molecular basis of K(+) selectivity and suggest a novel gating mechanism for this large and important family of membrane transport proteins [TrkH] (Mus musculus) PubMed

 7524.

This study showed that colony spreading of S. aureus involves the agr quorum-sensing system.[agr] (Mus musculus) PubMed

 7525.

the ygs gene controls Staphylococcus epidermidis biofilm accumulation and stress resistance[ygs] (Mus musculus) PubMed

 7526.

These data provide evidence of the importance of metacaspase processing into an active catalytic domain and of its role in disrupting mitochondria.[metacaspase] (Mus musculus) PubMed

 7527.

ORFV121 interacted with NF-kappaB-p65 in the cell cytoplasm and inhibited NF-kappaB-p65 phosphorylation and nuclear translocation. [RelA] (Mus musculus) PubMed

 7528.

The functional diversity of VPg is attributable to structural flexibility. [VPg] (Mus musculus) PubMed

 7529.

Unsuccessful attempts at disrupting the Pfark-1 gene with a knockout construct further indicate that Pfark-1 is required for parasite growth in red blood cells.[Pfark-1] (Mus musculus) PubMed

 7530.

Expressed NS4B protein hydrolyzes both ATP and GTP.[NS4B] (Mus musculus) PubMed

 7531.

Thus, in this system, infectious laryngotracheitis virus-miR-I5 decreased infectious laryngotracheitis virus ICP4 mRNA levels via transcript cleavage and degradation.[miR-I5] (Mus musculus) PubMed

 7532.

While deletion of espV from C. rodentium did not affect colonization dynamics or fitness in mixed infections, expression of EspV in mammalian cells led to drastic morphological alterations, which were characterized by nuclear condensation[EspV] (Mus musculus) PubMed

 7533.

The results here presented are consistent with the importance of the cyclic AMP signalling pathway in regulatory volume decrease and implicate TcrPDEC2 as a specifically localized phosphodiesterase involved in osmoregulation.[TcrPDEC2] (Mus musculus) PubMed

 7534.

Expression of Pik-mediated resistance requires the cooperation of two independent coiled-coil nucleotide binding site leucine-rich repeat genes, Pik-1 and Pik-2 (Pik-1 and Pik-2). (Mus musculus) PubMed

 7535.

The authors found that a mutant of Brh2 deleted of the non-canonical DNA-binding domain within the N-terminal region is dependent upon the presence of Rad52 for DNA repair activity.[Brh2] (Mus musculus) PubMed

 7536.

mitochondrial and cytosolic tryparedoxin peroxidases from T. cruzi are highly efficient peroxidases that reduce hydrogen peroxide and peroxynitrite [ tryparedoxin peroxidase] (Mus musculus) PubMed

 7537.

These data show that complex I is not only present in the procyclic stage of Trypanosoma brucei 29-13 strain, but it does participate in electron transport chain.[complex I] (Mus musculus) PubMed

 7538.

The authors showed that that the physical interaction of RpfG with two proteins with a diguanylate cyclase (GGDEF) domain, acts to control a sub-set of RpfG-regulated virulence functions.[RpfG] (Mus musculus) PubMed

 7539.

ROP18 phosphorylation of immunity related GTPases prevented clearance within inflammatory monocytes and IFN-gamma-activated macrophages, conferring parasite survival in vivo and promoting virulence.[ROP18] (Mus musculus) PubMed

 7540.

a potentially important role of calmodulins during early larval development [SmCaM1(03962); SmCaM2(07755)] (Mus musculus) PubMed

 7541.

aimed detect Shiga toxins (stx1 and stx2), enterohaemolysin and intimin virulence genes of 11 E. coli O157:H7 strains isolated from faecal samples of 300 clinically healthy Anatolian water buffaloes [stx1, stx2, EhlyA, intimin] (Mus musculus) PubMed

 7542.

These observations show that BiP and CRT activities complement each other to supervise a complete and efficient Trypanosoma cruzi CATL folding process.[BiP] (Mus musculus) PubMed

 7543.

In general, mutations in the capping enzyme decreasing the activity for GTP methylation also had correspondingly detrimental effects on virus accumulation.[capping enzyme] (Mus musculus) PubMed

 7544.

The binding kinetics between single molecules of bacteriophage T7 RNA polymerase and DNA was measured as a function of tension.[RNA polymerase] (Mus musculus) PubMed

 7545.

It was found that the asc1 null mutant was avirulent in a mouse model.[Asc1] (Mus musculus) PubMed

 7546.

the preferential polarities of Dmc1 and Rad51 strand exchange are different (Dmc1 promotes exchange in the 5'-to-3' and Rad51 promotes exchange in the 3'-to-5' direction relative to the ssDNA region of the DNA substrate [Dmc1, Rad51; no strain specified] (Mus musculus) PubMed

 7547.

A computational search assessing electrostatic interactions for multiple azimuthal locations, z-positions, and pseudo-rotations of tropomyosin on F-actin was performed. [F-actin] (Mus musculus) PubMed

 7548.

CDPK4 was a typical calcium-dependent protein kinase which had well-conserved N-terminal kinase domain and C-terminal calmodulin-like structure with 4 EF hand motifs for calcium-binding.[CDPK4] (Mus musculus) PubMed

 7549.

structure of the C-terminal domain of SpaP (residues 1136-1489) was solved and refined to 2.2 A resolution with six molecules in the asymmetric unit [SpaP] (Mus musculus) PubMed

 7550.

Data report the structure of the small laccase from Streptomyces coelicolor determined from a crystal soaked with potassium hexacyanoferrate [K4Fe(CN)6] [laccase]. (Mus musculus) PubMed

 7551.

bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 and Notch3, suggesting that ORF2 interfered with the trans-activation potential of Notch.[ORF2] (Mus musculus) PubMed

 7552.

Most critical was residue I405 in the thumb domain of the polymerase, which strongly stimulated replication in cell culture by enhancing overall de novo RNA synthesis.[NS5B] (Mus musculus) PubMed

 7553.

These data suggest that budding-competent neuraminidase proteins possess an as-yet-unidentified means of counteracting the antiviral restriction factor tetherin and identify a way in which the influenza virus neuraminidase can contribute to virus release. (Mus musculus) PubMed

 7554.

crystal structure of SEp22, a DNA-binding protein from starved cells has been determined in two forms: the native state at 1.25 A resolution and an iron-soaked form at 1.30 A resolution [SEp22] (Mus musculus) PubMed

 7555.

The SeqA protein could modulate periodically the initiation of replication of the pBR322 plasmid.[SeqA] (Mus musculus) PubMed

 7556.

The DROOPING LEAF (DL) gene, a member of the YABBY gene family, promotes midrib formation in the leaf and carpel specification in the flower. [DROOPING LEAF] (Mus musculus) PubMed

 7557.

CYP9M10 is linked to permethrin resistance in these strains of C. p. quinquefasciatus, and is likely to be the P450 gene responsible for resistance in these strains.[CYP9M10] (Mus musculus) PubMed

 7558.

Data describe the cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase DapL from Chlamydomonas reinhardtii [DapL]. (Mus musculus) PubMed

 7559.

The crystal structure of phenylalanyl-tRNA synthetase from E. coli, a class II aminoacyl-tRNA synthetase, complexed with phenylalanine and AMP. [phenylalanyl-tRNA synthetase subunit alpha, beta] (Mus musculus) PubMed

 7560.

Analyses of arginase activity show the bmarg-r gene is expressed in male reproductive organs, whereas the bmarg-f gene is expressed in larval and adult nonreproductive organs.[bmarg-r,bmarg-f] (Mus musculus) PubMed

 7561.

The structure of CLC of Synechocystis sp. PCC 6803 is nearly identical to that of E. coli. [CLC] (Mus musculus) PubMed

 7562.

BC1L4 encodes a COBRA-like protein that exhibits typical structural features of a glycosylphosphatidylinositol-anchor protein. (BC1L4) (Mus musculus) PubMed

 7563.

In the present study a homologue of ix was identified in Bombyx mori.[Bmix] (Mus musculus) PubMed

 7564.

Conditioning exposure can change the expression of F-actin in guinea pig cochlea. [F-actin] (Mus musculus) PubMed

 7565.

Sodium salicylate can promote the protein expression of NF-kappaB in cochlear spiral ganglion cells. [NF-kappaB] (Mus musculus) PubMed

 7566.

Crystal structure of the Thermotoga maritima sirtuin, Sir2Tm, bound to a propionylated peptide derived from p53. (Mus musculus) PubMed

 7567.

SAM-responsive box acts as a reversible switch modulating expression of the metK gene. [metK] (Mus musculus) PubMed

 7568.

Small regulatory RNA FasX enhances streptokinase activity by increasing the stability of the ska mRNA. [FasX] (Mus musculus) PubMed

 7569.

Aga1 is essential for appressorium formation and maintenance of the actin cytoskeleton. [Aga1] (Mus musculus) PubMed

 7570.

Purified CYP51 exhibited tight binding to azole antifungal agents such as ketoconazole, econazole, fluconazole, or itraconazole, with K(d) values around 0.26-0.84 muM.[CYP51] (Mus musculus) PubMed

 7571.

the identification of the glucose sensor Rag4 as a factor essential for oxygen-dependent regulation of the fermentative pathway.[Rag4] (Mus musculus) PubMed

 7572.

C-module-binding factor supports amplification of TRE5-A retrotransposons. [CbfA] (Mus musculus) PubMed

 7573.

MBF activator Rep2 plays a role in mediating the cell cycle-specific transcription through the recruitment of RNAP-II to the MBF-bound G(1)/S-phase genes. [MBF(DSC1)] (Mus musculus) PubMed

 7574.

conservation of insulin/insulin-like growth factor (IGF) functions in developmental speed control [IGF] (Mus musculus) PubMed

 7575.

Immediately adjacent positioning of genes can be functionally significant for their coregulated expression of MPP10 and YJR003C. [MPP10; YJR003C] (Mus musculus) PubMed

 7576.

study found evidence of three diffusely adherent (DAEC) strains expressing CS20-like molecules [CS20] (Mus musculus) PubMed

 7577.

Structural characterization of Escherichia coli BamE, a lipoprotein component of the beta-barrel assembly machinery complex (Mus musculus) PubMed

 7578.

UDP-glucose pyrophosphorylase is a regulated enzyme in E. histolytica [UDP-glucose pyrophosphorylase] (Mus musculus) PubMed

 7579.

TbrPPX1 represents the T. brucei exopolyphosphatase. It is located throughout the cytoplasm, and its genetic ablation does not produce a dramatic phenotype. [PPX1] (Mus musculus) PubMed

 7580.

results show that Rev1's catalytic activity is important in vivo when the cell has to cope with specific DNA lesions, such as N(2)-dG [rev1] (Mus musculus) PubMed

 7581.

rnlA-rnlB define a new toxin-antitoxin (TA) system [rnlA][rnlB] (Mus musculus) PubMed

 7582.

Although H. pylori infection is associated with higher serum levels of hs-CRP, serum concentrations of this inflammatory marker were not affected by expression of bacterial CagA virulence factor. (Mus musculus) PubMed

 7583.

These results demonstrated that RpoE promoted the expression of class-3 flagellar genes and it might be performed by initiating the expression of fliA in S. enterica serovar Typhi under hyperosmotic stress.[rpoE & fliA] (Mus musculus) PubMed

 7584.

Results describe an intragenic suppressor mutant for gid1, named Sgd-1, and reveal that gibberellin is not always required for interaction between its receptor, GID1, and DELLA proteins such as SLR1 [gid1, SLR1]. (Mus musculus) PubMed

 7585.

Data show that strains of X. oryzae pv oryzae can defeat the recessive resistance of xa13 by the deployment of any one of the alternate major type III TAL effectors PthXo2, PthXo3, or AvrXa7.022, due to the induction of the alternate S gene Os-11N3. (Mus musculus) PubMed

 7586.

NTR or AAT6 loss-of-function represent major potential mechanisms of resistance to these drugs [AAT6, NTR] (Mus musculus) PubMed

 7587.

Dug1p can recognize a variety of oligopeptides, but has evolved with post-binding screening potential to hydrolyze Cys-Gly peptides selectively.[Dug1p] (Mus musculus) PubMed

 7588.

Est3 may function as unusual GTPase in vivo (Mus musculus) PubMed

 7589.

applied a dynamic multisubstrate resolution system for the rapid evaluation of lipase performances of cyanohydrin structures[Amano Lipase PS-C-I] (Mus musculus) PubMed

 7590.

These data demonstrate that ExsD binds ExsA to block expression of T3SS1 genes, while ExsC binds ExsD to permit expression of T3SS1 genes. [ExsA, ExsC, ExcD] (Mus musculus) PubMed

 7591.

Spt2 is required for the major chromatin deposition pathway that uses old histones to refold nucleosomes in the wake of RNA polymerase II at the SRG1-SER3 locus. [SRG1] (Mus musculus) PubMed

 7592.

This analysis suggests that the direct activation of a lipid kinase PI4KA by hepatitis C virus NS5A contributes critically to the integrity of the membranous viral replication complex. (Mus musculus) PubMed

 7593.

The frequency of URE3 prion occurrence is very low in Kluyveromyces lactis, well below that of the (ure2-) mutation, such that it may even be impossible to obtain this prion.[URE3] (Mus musculus) PubMed

 7594.

Pleiotropic effects were less evident in the o7 mutant, but severe in the o2 and o2o7 backgrounds, with large changes in gene expression patterns, affecting a broad range of kernel-expressed genes. [Opaque-7] (Mus musculus) PubMed

 7595.

HSP83 protein is involved in protection against heat stress and could be involved in oogenesis during ovarian maturation of T. castaneum. [hsp83] (Mus musculus) PubMed

 7596.

These observations suggest that CT703 may be an important regulator for promoting chlamydial productive infection.[CT703] (Mus musculus) PubMed

 7597.

Wld-type allene oxide synthase (AOS) from Arabidopsis or rice in fact produces both AOS and hydroperoxide lyase products in a ratio of about 80:15, something that was found only in trace amounts before. (Mus musculus) PubMed

 7598.

These results suggest that down-regulation of quorum sensing by excess LsrR can lower Salmonella virulence by hampering Salmonella evasion from oxidative killing within macrophages.[LsrR] (Mus musculus) PubMed

 7599.

purification and detailed characterization of a novel helicase from P. falciparum and show that this helicase is a homologue of Dbp5 and DDX19 from yeast and human, respectively[ddp5/DDX19] (Mus musculus) PubMed

 7600.

substrate specificity of the enzyme produced in E. coli [CdpA] (Mus musculus) PubMed

 7601.

cHSP60- and cHSP10-induced caspase expression, proinflammatory cytokine production and apoptosis of primary cervical epithelial cells might play a role in the pathogenesis of infertility in women with persistent chlamydial infection [Hsp10]. (Mus musculus) PubMed

 7602.

IgA1 protease might contribute to S. suis pathogenesis. (Mus musculus) PubMed

 7603.

The immediate early gene 2 is duplicated in the genome of bovine herpesvirus 4 isolate U. [IE2] (Mus musculus) PubMed

 7604.

The authors demonstrate a role of GCS3 in plasminogen-dependent streptococcal adherence to human pharyngeal cells (cell line Detroit 562) that indicates an additional function of the protein as an adhesin in the oral cavity.[GCS3] (Mus musculus) PubMed

 7605.

Cbk1-mediated phosphorylation of Ssd1 promotes the cortical localization of Ssd1-mRNA complexes. [CBK1] (Mus musculus) PubMed

 7606.

qnrS1 is a quinolone resistance gene. [qnrS1] (Mus musculus) PubMed

 7607.

The aim of this study was to develop molecular markers for Sr13 facilitating efficient pyramiding of Sr genes.[Sr13] (Mus musculus) PubMed

 7608.

The recombination between leaf rust resistance gene Lr53 and stripe rust resistance gene Yr35, to identify simple sequence repeats markers linked to these genes, and to determine linkage relationships between Lr53 and Lr36.[Lr35, Yr35, Lr36] (Mus musculus) PubMed

 7609.

(IE-1) Human cytomegalovirus major immediate early protein (IE)1 of 72 kDa associates with metaphase chromatin, recruiting both tumor suppressor protein IE1-of 72kDa, recruiting both promyelocytic protein (PML) and STAT2. (Mus musculus) PubMed

 7610.

SspA of S. suis shared similarities with subtilisin-like proteases produced by other pathogenic streptococci and may contribute to the pathogenic process of S. suis infections. [SspA] (Mus musculus) PubMed

 7611.

Sequence analysis of full-length endoglucanase 1 (TcEG1) cDNA clone shows sequence homology to glycosyl hydrolase family 9 (GHF9) enzymes & verified presence of a change (Gly for Ser) in the conserved catalytic domain for GHF9 cellulases. [TcEG1] (Mus musculus) PubMed

 7612.

results suggest that OsRad21-2 functions in regulation of cell division and growth[Rad21-2] (Mus musculus) PubMed

 7613.

These results demonstrate that Pac1 negatively regulates Tri gene expression and toxin production in Fusarium graminearum.[Pac1 & Tri] (Mus musculus) PubMed

 7614.

These results strongly support a model in which HU binds to and stabilizes the stacked-X DNA conformation. [HU] (Mus musculus) PubMed

 7615.

Tem1 is required at the spindle pole bodies for the proper function of the mitotic exit network and spindle position checkpoint. (Mus musculus) PubMed

 7616.

[NS-5A] An amphipathic alpha-helical peptide [C5A] of hepatitis C virus derived from its nonstructural 5A membrane anchor domain is a chemoattractant and activator of phagocytic leukocytes via the host formyl peptide receptor. (Mus musculus) PubMed

 7617.

A repression of phloem feeding was induced by HrpNEa in wild-type (WT) Arabidopsis but not in atpp2-a1/E/142, the plant mutant that had a defect in the AtPP2-A1 gene, the most HrpNEa-responsive of 30 AtPP2 genes.[HrpNEa] (Mus musculus) PubMed

 7618.

These results allowed the conclusion that TolC plays an important role as a virulence and fitness factor of Erwinia amylovora by mediating resistance towards phytoalexins through its exclusive interaction with AcrAB.[TolC] (Mus musculus) PubMed

 7619.

EpsL may function as a scaffold to link EpsG and EpsE and thereby transduce the energy generated by ATP hydrolysis to support secretion. [EpsL, EpsG] (Mus musculus) PubMed

 7620.

The binding of 14-3-3 proteins to Yak1 coincides with PKA activity and such regulatory mechanisms might allow cytoplasmic retention of an inactive form of Yak1 under high glucose conditions.[Yak1, PKA, Bmh1] (Mus musculus) PubMed

 7621.

Full kinase activation involves interaction of CheA with groups of three receptor dimers, presumably as a trimer of dimers, and that more extensive interactions among receptors are not necessary for full kinase activation.[CheA] (Mus musculus) PubMed

 7622.

DksA2 plays a role in Zn homeostasis and serves as a back-up copy of the canonical Zn-dependent DksA in Zn-poor environments.[DksA] (Mus musculus) PubMed

 7623.

MrpA is a new site-specific tyrosine recombinase that acts with mrpS. [MrpA] (Mus musculus) PubMed

 7624.

Using this HSF1 CE2 deletion mutant the authors demonstrate that Hsf1 activation, and hence thermal adaptation, contributes significantly to the virulence of Candida albicans.[Hsf1] (Mus musculus) PubMed

 7625.

Two COL17A1 orthologues were identified in the zebrafish genome, col17a1a and col17a1b, which are expressed in the skin and the neural system, respectively. (col17a1a and col17a1b) (Mus musculus) PubMed

 7626.

EPG-8 may function as a highly divergent homolog of the yeast autophagy gene Atg14. (Mus musculus) PubMed

 7627.

results indicate that a discrete surface of the urease UreA-UreB complex is important for Helicobacter pylori strain X47 persistence during gastric colonisation [UreA & UreB] (Mus musculus) PubMed

 7628.

Data show that in the G3 strain of An. gambiae AgApoLp-III participates in midgut epithelial defense responses that limit Plasmodium infection: [ApoLp-III] (Mus musculus) PubMed

 7629.

Data show that CovR directly binds to the putative promoter region of SMU.1882 [SMU.1882] (Mus musculus) PubMed

 7630.

These studies demonstrate that Cryptococcus neoformans CRK1 gene functions as a negative regulator in the mating differentiation.[CRK1] (Mus musculus) PubMed

 7631.

Wheat head infection by the disruptants was severely attenuated, indicating the involvement of FgATG15 in pathogenesis.[ATG15] (Mus musculus) PubMed

 7632.

The decrease in Noa1 expression level resulted in a decrease in NO production in roots, but not in symbiotic nodules. [Noa1] (Mus musculus) PubMed

 7633.

study showed that P-TEFb and Dengue virus (DENV) core protein work in concert to enhance IL-8 gene expression by DENV infection [core protein] (Mus musculus) PubMed

 7634.

Pirenzepine may affect Smad3 signaling pathway and CTGF in the sclera by inhibiting the development of form deprivation myopia. [Smad3; CTGF] (Mus musculus) PubMed

 7635.

TaSnRK2.7 is involved in carbohydrate metabolism, decreasing osmotic potential, enhancing photosystem II activity, and promoting root growth. [SnRK2.7] (Mus musculus) PubMed

 7636.

CBL4 is the barley homologue of the Arabidopsis SOS3 controlling the Na+ transport. [CBL4] (Mus musculus) PubMed

 7637.

The results indicate that during glycerol fermentation, H+ was expelled via F1F0. [F1F0] (Mus musculus) PubMed

 7638.

MDR2 is proposed to modulate antifolate responses, possibly mediated by the transport of folate intermediates.[MDR2] (Mus musculus) PubMed

 7639.

miRNA-488 is one of regulator in cell to ECM (extracellular matrix) interaction through modulation of focal adhesion activity by MMP-2 during chondrogenesis of limb mesenchymal cells. (Mus musculus) PubMed

 7640.

The authors showed that substitutions of neuraminidase (NA) residues 234, 241, 257, 286 and 345, adversely affected the NA-mediated viral particle release, suggesting that these residues are critical for NA enzymatic activity.[NA] (Mus musculus) PubMed

 7641.

A heparin binding site motif in members of the Duffy binding protein family may form part of a conserved erythrocyte receptor binding pocket. (Mus musculus) PubMed

 7642.

HTLV-1 p30 interacts with ATM and REGgamma to increase viral spread by facilitating cell survival (Mus musculus) PubMed

 7643.

Analysis of 656 full-length sequences from 13 parasite populations in Africa, Asia, Oceania, and South America revealed 64 single nucleotide polymorphisms (SNPs), of which 43 were newly identified and 38 resulted in amino acid substitutions [PfATP6] (Mus musculus) PubMed

 7644.

we report identification and characterization of a novel 62-amino acid peptide, designated as hemolymph major anionic peptide (HemaP), from the hemolymph of Bombyx mori larvae that induces foraging behaviors[HEMAP] (Mus musculus) PubMed

 7645.

SdrE has been previously proposed to play role in bone infections, whilst our results can indicate that sdrD plays a role in the interactions between the pathogen and human human blood.[sdrD & sdrE] (Mus musculus) PubMed

 7646.

A novel galanin type I-like receptor is characterized. (Mus musculus) PubMed

 7647.

Results show that the RNA toxicity induced by expanded CAG and CUG repeats can be mediated, at least in part, through the functional alteration of muscleblind protein in Caenorhabditis elegans [muscleblind]. (Mus musculus) PubMed

 7648.

ADT-2 is required for normal levels of expression of a DBL-1-responsive transcriptional reporter.[ADT-2, DBL-1] (Mus musculus) PubMed

 7649.

It is proposed that serine phosphorylation of hepatitis C virus E2 gene has a significant role in interferon resistance.[E2] (Mus musculus) PubMed

 7650.

The F103L and M106I NS1 mutations were adaptive genetic determinants of growth and virulence in both human and avian NS1 genes in the mouse model.[NS1] (Mus musculus) PubMed

 7651.

The authors found that the envelope proteins of genotype 1 were fully functional in genotype 2 porcine reproductive and respiratory syndrome virus, and the chimeric progeny viruses showed robust genetic stability and replication properties in vitro. (Mus musculus) PubMed

 7652.

Two cDNA clones coding for alpha-type carbonic anhydrases (CA; EC 4.2.1.1) in the nitrogen-fixing nodules of the model legume Lotus japonicus were identified.LjCAA1, LjCAA2] (Mus musculus) PubMed

 7653.

Zcf37 acts as an activator of white cell formation and a repressor of opaque state and functions upstream of Efg1.[Zcf37] (Mus musculus) PubMed

 7654.

The authors now report that the influenza C virus NS1 protein also inhibits the RIG-I-mediated IFN signalling.[NS1] (Mus musculus) PubMed

 7655.

LdCSBP Smr domain independently possesses both DNA and RNA endonuclease activities, but the full-length LdCSBP exhibits only riboendonuclease activity.[LdCSBP] (Mus musculus) PubMed

 7656.

sequenced the Pv200L coding region of MSP-1; found two new alleles and several previously unidentified dimorphic substitutions and significant size polymorphism [MSP-1] (Mus musculus) PubMed

 7657.

full-length sequences of msp1p gene were generally highly conserved; they had a few amino acid substitutions, 1 highly polymorphic E/Q-rich region and a single-to-triple hepta-peptide repeat motif; 21 allelic types of E/Q-rich region identified [msp1p] (Mus musculus) PubMed

 7658.

The MtCRE1-dependent cytokinin pathway is required to regulate Nod factor signaling genes. [CRE1] (Mus musculus) PubMed

 7659.

GcpA is critical for cellulose production and biofilm formation on polystyrene surface. [GcpA] (Mus musculus) PubMed

 7660.

Alanine-substitution within Core regions I, II, III and IV of classical swine fever virus identified residues that specifically mediate the Core-IQGAP1 interaction.[Core] (Mus musculus) PubMed

 7661.

The authors conclude that dengue virus type-1 M protein does not show pH-activated ion channel activity.[M] (Mus musculus) PubMed

 7662.

P. patens encodes BOP-like genes that are post-transcriptionally regulated by Pp-miR534. Deletion of PpMIR534a causes elevated PpBOP1/2 transcript levels and early formation of gametophores. [miR534] (Mus musculus) PubMed

 7663.

Pep was a luxO-regulated extracellular protein and involved in the motility. [Pep, luxo] (Mus musculus) PubMed

 7664.

The four loci of DLK1 gene and CLPG gene in 1109 individuals, which belong to eight breeds/species of bovidae, including cattle, buffalo and yak, were analyzed. (Mus musculus) PubMed

 7665.

Bidirectional motor learning, like bidirectional synaptic plasticity, requires the activation of mGluR1 in the cerebellar cortex. Without mGluR1 activity, learning becomes unidirectional. mGluR1. (Mus musculus) PubMed

 7666.

The study determined that the mismatch repair initiation protein MutS forms a transient clamp that scans duplex DNA for mismatched nucleotides by 1D diffusion for 1 s (~700 base pairs) while in continuous rotational contact with the DNA. [MutS] (Mus musculus) PubMed

 7667.

Coupling SlmA activation to specific DNA binding provides a mechanism for the precise spatiotemporal control of its anti-FtsZ activity within the cell.[SlmA, FtsZ] (Mus musculus) PubMed

 7668.

It was found that homotropic allostery between the two active sites of the homodimeric enzyme is modulated by opposing mechanisms. [aminoglycoside N-(6')-acetyltransferase-Ii] (Mus musculus) PubMed

 7669.

The study reports the crystal structures of Kluyveromyces lactis Xrn1 (residues 1-1,245, E178Q mutant), alone and in complex with a Mn(2+) ion in the active site. [Xrn1] (Mus musculus) PubMed

 7670.

Down-regulation of Hel61 [renamed REH1 (RNA editing helicase 1)] expression in Trypanosoma brucei selectively affects editing mediated by two or more overlapping guide RNAs.[REH1] (Mus musculus) PubMed

 7671.

The study shows that the structure of FliJ derived from Salmonella enterica serovar Typhimurium is remarkably similar to that of the two-stranded alpha-helical coiled-coil part of the gamma subunit of F(o)F(1)-ATP synthase. [FliJ] (Mus musculus) PubMed

 7672.

we identified CD4, CD8alpha and CD8beta gene homologs both in Xenopus tropicalis, whose full genome has been sequenced, and its sister species Xenopus laevis [CD4, CD8 alpha and beta] (Mus musculus) PubMed

 7673.

Data show that CtkA from H. pylori J99 is a unique eukaryotic-type Ser/Thr kinase that translocates into human cells to up-regulate the NF-kappaB activity in a kinase-dependent manner [CtkA/JHP940]. (Mus musculus) PubMed

 7674.

Results describe the NMR structure of insulin receptor tyrosine kinase substrate (IRTKS) SH3 domain in complex with a repeat from Escherichia coli-secreted protein F-like protein encoded on prophage U [EspF(U)] (Mus musculus) PubMed

 7675.

The ion concentration-dependent changes in the thermal stability of the protein, evaluated as the Tm value for thermal-induced denaturation of the protein, may suggest the existence of both high- and low-affinity K+ binding sites of KcsA. (Mus musculus) PubMed

 7676.

SAM enzymes identified that methylate C atoms not inherently nucleophilic via intermediacy of 5'-deoxyadenosyl 5'-radical; determined reaction mechanism targeting sp(2)-hybridized carbons at position 2 and 8 of adenosine in 23S RRNA catalyzed by Cfr [Cfr] (Mus musculus) PubMed

 7677.

Affected lambs were found to be deficient in glucocerebrosidase activity, and mutational analysis found them to be homozygous for the missense mutations c.1142G>A (p.C381Y) and c.1400C>T (p.P467L).[beta glucocerebrosidase, sheep]. (Mus musculus) PubMed

 7678.

Respiratory infection of mice with an N1L deletion mutant virus (ECTVDeltaN1L) demonstrated profound attenuation of the mutant virus, confirming N1 as an orthopoxvirus virulence factor. (Mus musculus) PubMed

 7679.

OsHAK5 functions as a Na+-insensitive K+ transporter, while OsHAK2 is sensitive to extracellular Na+ and exhibits higher Na+ over K+ transport activities. [HAK2; HAK5] (Mus musculus) PubMed

 7680.

dynein controls kinesin-3 activity on the early endosomes and thereby determines the long-range motility behavior of the organelles.[Dynein heavy chain] (Mus musculus) PubMed

 7681.

crystal structure of the FGL1 gene product, an extracellular lipase of gibberella zeae (GZEL) (Mus musculus) PubMed

 7682.

the role of the FAD moiety conformation and the structural determinants involved in stabilizing it, ultimately modulating the functional output of ferredoxin-NADP(H) reductases [FNR] (Mus musculus) PubMed

 7683.

high-resolution structure of the extracellular region of PrkC: reveals typical features of adhesive proteins [PrkC, protein kinase C (a serine/threonine kinase)] (Mus musculus) PubMed

 7684.

HyaS induces tight fusion-like contacts among hyphae. [HyaS] (Mus musculus) PubMed

 7685.

Mutations in the polymerase proteins PB1 and PB2 played a crucial role in the temperature sensitive growth phenotype of cold-adapted A/Leningrad/134/17/57 (H2N2) virus.[PB1 & PB2] (Mus musculus) PubMed

 7686.

Collectively, these results demonstrate that foot-and-mouth disease virus Lb(pro) possesses deubiquitinase activity in addition to serving as a viral proteinase.[Lb(pro)] (Mus musculus) PubMed

 7687.

Overexpression of acrA and acrB overexpression storngly correlated with fluoroquinolone and multidrug resistance. [acrA,acrB] (Mus musculus) PubMed

 7688.

Azole susceptibility, ergosterol levels, and expression of ERG genes were elevated in an A643V amino acid substitution in Upc2p transcription factor. [Upc2p] (Mus musculus) PubMed

 7689.

These results indicate that key cellular functions of Ufd2 and Ufd3 in proteasomal protein degradation require their interaction with Cdc48.[Ufd2, Ufd3, Cdc48] (Mus musculus) PubMed

 7690.

The binding of a phosphate ion to the Escherichia coli phosphate-binding protein, was studied.[PBP] (Mus musculus) PubMed

 7691.

Cells that might otherwise recover from damage or injury are destroyed in progranulin mutants, which in turn facilitates disease progression.[PGRN-1] (Mus musculus) PubMed

 7692.

pol V and pol IV compete to carry out error-prone bypass of the G[8,5-Me]T cross-link [DNA polymerase IV][DNA poymerase V] (Mus musculus) PubMed

 7693.

replacement of Ile274 results in a reduction in catalytic efficiency [HPII] (Mus musculus) PubMed

 7694.

This study found that state mutant versions of cohesin colocalize with Scc2/4 at core centromeres, sites that catalyze wild-type cohesin's recruitment to sequences 20 kb or more away.[cohesin; Scc2; Scc4] (Mus musculus) PubMed

 7695.

Docking of eIF2alpha on PKR induces a conformational change that regulates the degree of Ser51 exposure and thus restricts phosphorylation to the proper kinases.[PKR, eIF2alpha] (Mus musculus) PubMed

 7696.

Amino acids outside the core-binding region of PB1 are essential for PA binding. {PB1, PA] (Mus musculus) PubMed

 7697.

Viruses expressing the hemagglutinin of pandemic influenza A viruses were associated with significant pathology in the lower respiratory tract, including acute inflammation, and showed low binding activity for lung surfactant protein D.[HA] (Mus musculus) PubMed

 7698.

structures and ligand binding insights [DHQD] (Mus musculus) PubMed

 7699.

[OsCCC1] cloning and demonstration of a significant role in K+ and Cl- homeostasis and development (Mus musculus) PubMed

 7700.

[OsIRO2] required under iron deficient conditions and role in germination and seed maturation (Mus musculus) PubMed

 7701.

gene expression and DNA methylation of OsMAPK2 in the process of callus formation [MAPK2] (Mus musculus) PubMed

 7702.

OsPSK3 increases chlorophyll content of leaves in rice [PSK3] (Mus musculus) PubMed

 7703.

The function of 28-residue asparagine repeat present in the P. falciparum proteasome lid subunit 6, Rpn6, was analyzed.[Rpn6] (Mus musculus) PubMed

 7704.

demonstrate for the first time in fish the presence of both PACAP transcriptional variants [PACAP]in spleen (Mus musculus) PubMed

 7705.

data demonstrate that both mammalian and teleost FXR (Fxralpha2 isoform) are activated by primary and secondary bile acids [Fxralpha] (Mus musculus) PubMed

 7706.

Increased caspase 12 expression causes endoplasmic reticulum stress-related apoptosis in cochlea cells after exposure to intense noise. (Mus musculus) PubMed

 7707.

These results indicate that arginine activates the MTOR/FRAP1-ribosomal protein S6 kinase, k-90 (RPS6K)-RPS6 signaling pathway in ovine trophectoderm cells.[RPS6K] (Mus musculus) PubMed

 7708.

The newly cloned ovine FcgammaRIII cDNA contains a 940 bp open-reading frame, and is predicted to encode a 250 amino acid glycoprotein composed of two extracellular domains, a transmembrane region and a short cytoplasmic tail.[FcgammaRIII] (Mus musculus) PubMed

 7709.

MT1-MMP plays a crucial role in RAGE-activated NADPH oxidase-dependent signaling pathways.[RAGE] (Mus musculus) PubMed

 7710.

functional interaction between RNA polymerase and RapA [RapA] (Mus musculus) PubMed

 7711.

Further evidence for the specific interaction of G3 and L5 was obtained by mass spectrometry.[G3] (Mus musculus) PubMed

 7712.

In addition to rcnA, RcnR controls expression of its own gene in response to Ni and Co, but the two genes are differentially expressed [RcnR][RcnA] (Mus musculus) PubMed

 7713.

analysis of Pap1-dependent regulation of the Schizosaccharomyces pombe spy1 gene under nitrosative and nutritional stresses [spy1] (Mus musculus) PubMed

 7714.

analysis of site-directed mutagenesis of phyI1s from Aspergillus niger (Mus musculus) PubMed

 7715.

The genetics and phenotyping of CMY-2 beta-lactamase (bla CMY-2) producing Salmonella typhimurium in Japanese cattle are reported.[bla CMY-2] (Mus musculus) PubMed

 7716.

analysis of cloning and enzyme structure modeling of the Aspergillus oryzae N74 fructosyltransferase [FTase] (Mus musculus) PubMed

 7717.

the mechanism of ADP arsenolysis mediated by Escherichia coli PNPase [polynucleotide phosphorylase] (Mus musculus) PubMed

 7718.

the structure of D-serine dehydratase [D-serine dehydratase] (Mus musculus) PubMed

 7719.

crystal structure of catalytic core of methionyl-tRNA synthetase [methionyl-tRNA synthetase] (Mus musculus) PubMed

 7720.

Crystal structure of curcuminoid synthase from Oryza sativa (Mus musculus) PubMed

 7721.

The 972 bp length of transaldolase gene tal was cloned from Pichia stipitis CICC1960, encoding a 323 amino acid protein with a calculated molecular mass of 35.36 kDa and isoelectric point of 5.20.[Tal] (Mus musculus) PubMed

 7722.

rAaTI can probably inhibit thrombin by interacting with thrombin exosite 2 [rAaTI] (Mus musculus) PubMed

 7723.

Overexpression of stuA increased the transcript levels of brlA and abaA (another developmental regulator) and derepressed conidiation during liquid-submerged growth but did not affect penicillin V productivity. [StuA, BrlA (Mus musculus) PubMed

 7724.

investigation of role of IE2 in up-regulation of host IL8 metabolism/secretion (bovine BoHV-4 induced endometritis cell model) [IE2; Immediate Early 2; ORF50; Rta] (Mus musculus) PubMed

 7725.

ArgR can affect FarR binding to the argB promoter region, as protein binding is dominated by the protein most able to do so. [FarR] (Mus musculus) PubMed

 7726.

Overexpression of MAIF1 reduces abiotic stress tolerance and promotes root growth. [MAIF1] (Mus musculus) PubMed

 7727.

our results suggest that IPSE/alpha-1 from schistosome eggs may have additional nuclear functions in host cells. [IPSE] (Mus musculus) PubMed

 7728.

We identified a novel effector protein in the repertoire of V. cholerae, annotated as A33_1663 and herein named VopX [VopX] (Mus musculus) PubMed

 7729.

These results identify acidic patch residues of H2A.Z that are critical for mediating deposition and function in chromatin.[H2A.z] (Mus musculus) PubMed

 7730.

The present article reports on the characterization of the urochordate metallothionein (MT) gene, CiMT-1, from the solitary ascidian Ciona intestinalis. [CiMT-1] (Mus musculus) PubMed

 7731.

A model of the regulation of the lpfA1 operon of E. coli O157:H7 by H-NS and Ler is discussed.[H-NS; Ler; lpfA1] (Mus musculus) PubMed

 7732.

This study investigated a previously uncharacterized gene, esaD, downstream of esxB.[esaD] (Mus musculus) PubMed

 7733.

This study demonstrated that FsrA binds to two imperfect direct repeats separated by 13 bp, based on the consensus sequence of FsrA, T/AT/CAA/GGGAA/G, which is consistent with the binding characteristics of LytTR domains.[FsrA] (Mus musculus) PubMed

 7734.

The SRS1 mRNA and proteins are abundant in wild type rice specifically in young organs, namely young leaves, internodes and panicles [SRS1] (Mus musculus) PubMed

 7735.

Mid1p contributes to controlling cell cycle-specific gene expression as part of a feedback loop.[Mid1p] (Mus musculus) PubMed

 7736.

Clp1p controls cell cycle-specific gene expression through binding to and dephosphorylating Mbx1p.[Clp1p] (Mus musculus) PubMed

 7737.

crystal structure of Aspergillus oryzae carbonic anhydrase [alpha-type carbonic anhydrase] (Mus musculus) PubMed

 7738.

unfolded protein response (UPR) in Pichia pastoris requires splicing of a non-conventional intron in the HAC1(u) mRNA [HAC1] (Mus musculus) PubMed

 7739.

AHD of Arv1 is required for mating, pheromone-induced G1 cell cycle arrest, and for sterol trafficking [Arv1, strain w303] (Mus musculus) PubMed

 7740.

Debaryomyces hansenii has two genes (DhCTA1 and DhCTT1) encoding two catalase isozymes with a differential enzymatic activity profile which is not strictly correlated with a differential expression profile of the encoding genes.[CTA1 & CTT1] (Mus musculus) PubMed

 7741.

A novel LDH homologue, designated as BmLDH1, was firstly identified and characterized from the silkworm, Bombyx mori.[BmLDH1] (Mus musculus) PubMed

 7742.

NMR solution structure and function of BamE within the outer membrane and the beta-barrel assembly machine. [BamE] (Mus musculus) PubMed

 7743.

The MET15 gene encodes O-acetyl homoserine thiolase. Disruption leads to strict organic sulfur auxotrophy. [MET15] (Mus musculus) PubMed

 7744.

Mutation of the S. epidermidis tagO gene has pleiotropic effects, including impaired biofilm production and increased autolytic activity. [TagO] (Mus musculus) PubMed

 7745.

The latch, an insertion into the helicase-like domain of reverse gyrase, coordinates the individual domain activities by modulating the helicase-like domain, and by communicating changes in the nucleotide state to the topoisomerase domain(reverse gyrase). (Mus musculus) PubMed

 7746.

we cloned and expressed full-length vibriolysin gene from V. cholerae [vibriolysin] (Mus musculus) PubMed

 7747.

Xray structural explanation for the pathological properties of the complex formed between streptococcal M1 and human fibrinogen [M1] (Mus musculus) PubMed

 7748.

ZmPep1 pretreatment was found to enhance resistance to both southern leaf blight and anthracnose stalk rot caused by Cochliobolis heterostrophus and Colletotrichum graminicola, respectively.[ZmPep1] (Mus musculus) PubMed

 7749.

LRP is involved in lipoprotein endocytosis and parasite replication.[LRP] (Mus musculus) PubMed

 7750.

MscL self-assembly into channel clusters plays an osmoregulatory functional role in the membrane [MscL] (Mus musculus) PubMed

 7751.

These results showed that IL-1beta and IL-1 receptor types I and II (IL-1R type 1, IL-1R type II) were expressed in the ovine hypothalamus in response to lipopolysaccharide injection.[IL-1R type 1; IL-1R type 2] (Mus musculus) PubMed

 7752.

Activation Induced Cytidine Deaminase (AID)-induced translocations were strongly enhanced in yeast THO null mutants, consistent with the idea that AID-mediated DSBs depend on R-loop formation[Activation Induced Cytidine Deaminase] (Mus musculus) PubMed

 7753.

Results describe a model for full-length GBS80 (N1, N2, and N3) with the help of available homologous major pilin structures, and suggest a model for the GBS PI-1 pilus shaft [GBS80]. (Mus musculus) PubMed

 7754.

Our results reveal a novel binding mode between the Sec1p C-terminal tail and the SNARE complex, and suggest a role for Mso1p as an effector of Sec4p (Sec1p, Mso1p) (Mus musculus) PubMed

 7755.

A report on the crystal structure of NpmA and its complex with AdoMet and AdoHcy, along with structure-guided functional and modeling studies (NpmA). (Mus musculus) PubMed

 7756.

a novel major transcript of the Oryzias latipes AIFL gene that retained intron 4 (AIFL-I4) in embryos and tissues from adult fish was identified. [AIFL] (Mus musculus) PubMed

 7757.

propose that NhABC1 and the cytochrome P450 may function in a sequential manner in which the energy expense from pisatin efflux by NhABC1 releases the repression of the cytochrome P450, ultimately allowing pisatin tolerance by two mechanisms [ABC1] (Mus musculus) PubMed

 7758.

OsCIPK10 decreases under high salt and increases in low potassium conditions. [CIPK10] (Mus musculus) PubMed

 7759.

investigation of molecular conformation and Mg2+ and Na+ binding sites during catalysis [HDV ribozyme] (Mus musculus) PubMed

 7760.

These results provide evidence that Osg1 is essential for timely callose degradation in the process of tetrad dissolution.[Osg1] (Mus musculus) PubMed

 7761.

Rre37 is involved in induction of glycolytic and glycogen catabolic genes during nitrogen depletion. [Rre37] (Mus musculus) PubMed

 7762.

The fission yeast casein kinase 1 (CK1) delta/epsilon isoforms Hhp1 and Hhp2 are required for full levels of Rec8 phosphorylation and for efficient removal of Rec8 at the onset of anaphase I.[Rec8, Hhp1, Hhp2] (Mus musculus) PubMed

 7763.

We report that Glycosomal ABC transporters GAT1 and GAT3 are expressed both in bloodstream and procyclic form trypanosomes, whereas GAT2 is mainly or exclusively expressed in bloodstream-form cells. [GAT1, GAT2, GAT3] (Mus musculus) PubMed

 7764.

GDF11 has a central role in the activation of Smad2 phosphorylation in tailbud stage Xenopus embryos.[GDF11] (Mus musculus) PubMed

 7765.

Data show that constitutive expression of IL-IL-23 p19 was observed in the kidney, liver, gut and muscle: [IL-23 p19] (Mus musculus) PubMed

 7766.

(RGEF-1b) RasGRP protein RGEF-1b couples external stimuli to behavior by activating LET-60 protein in sensory neurons. (Mus musculus) PubMed

 7767.

in Xenopus ovarian follicles FP receptors play an important role during gonadotropin- and progesterone-induced ovulation [prostaglandin F2alpha receptor isoform A][prostaglandin F2alpha receptor isoform B] (Mus musculus) PubMed

 7768.

Infection with a H. pylori strain containing the dupA without the stop codon polymorphisms is associated with a lower risk of development of gastric carcinoma in Brazilian subjects.[dupA] (Mus musculus) PubMed

 7769.

roles of active site polar residues Glu47, Gln110, Lys159, and His251 for elementary steps of catalysis [AHAS II] (Mus musculus) PubMed

 7770.

a conformational change as a result of substrate binding [YidC] (Mus musculus) PubMed

 7771.

crystal structure of a representative NAT protein, the Escherichia coli uracil/H(+) symporter UraA, in complex with uracil at a resolution of 2.8 A [UraA] (Mus musculus) PubMed

 7772.

The authors showed that thermal unfolding of the autochaperone region is reversible and determined its crystal structure at 2.0-A resolution.[IscA] (Mus musculus) PubMed

 7773.

the in vitro incorporation of methylmalonyl groups ligated by MatB to CoA, pantetheine, or N-acetylcysteamine into a triketide pyrone by the terminal module of the 6-deoxyerythronolide B synthase [MatB] (Mus musculus) PubMed

 7774.

The results of this study show that the anti-apoptotic proteins, HSP70 and alpha-BC, were overexpressed with increased apoptosis in foot-and-mouth disease virus-infected heart tissues.[HSP70] (Mus musculus) PubMed

 7775.

The authors show that at least two foamy virus protease-reverse transcriptase molecules bind to the protease-activating RNA motif and only RNAs containing this motif result in significant activation of the protease.[protease] (Mus musculus) PubMed

 7776.

Mutations in ArsD near the metalloid binding site and on the surface of the helix 1 affect binding with the ArsA ATPase. [ArsD] (Mus musculus) PubMed

 7777.

CgYPS1 is essential for survival in the post-diauxic growth phases, and is required to survive low-pH environment. [Yps1] (Mus musculus) PubMed

 7778.

STE50 is involved in multiple steps of sexual reproduction, andfunctions between Ste11p and Ste20p as an adapter protein and regulates the activation of Ste11p. [STE50] (Mus musculus) PubMed

 7779.

A cleaved amplified polymorphic sequence (CAPS) marker that is associated with the presence or absence of the S2 gene was developed in 115 of 122 (95%) diverse wheat lines.[Sr2] (Mus musculus) PubMed

 7780.

SAP1 is involved in a selective post-transcriptional mechanism to regulate the abundance of transcripts critical to the infectivity of sporozoites. [Sap1] (Mus musculus) PubMed

 7781.

Zcf37p is the DNA binding factor that recruits Mcm1p to target promoters that directly activate adhesion genes. [Ahr1] (Mus musculus) PubMed

 7782.

The authors show that the function of SsuR is essential for the utilization of a number of organic sulfur sources of either environmental or human origin.[SsuR] (Mus musculus) PubMed

 7783.

CYP78As participate in the synthesis of a critical growth regulator in P. patens [CYP78A] (Mus musculus) PubMed

 7784.

amphioxus Vasa and Nanos are also expressed zygotically in the tail bud[Vasa] (Mus musculus) PubMed

 7785.

The potential activity of E coli GalE for free monosaccharide, was determined.[GalE] (Mus musculus) PubMed

 7786.

without Chp signaling, E-cadh shifts to intracellular vesicles rather than the adhesive contacts needed for directed cell movement during epiboly. [Chp] (Mus musculus) PubMed

 7787.

the single nucleotide heterogeneity (A at M847) in the Gn protein substantially affected the RVFV virulence [Gn envelope protein] (Mus musculus) PubMed

 7788.

Sak189 response regulator is necessary for activation of bac gene transcription. It also controls the virulent properties of S. agalactiae [Sak189] (Mus musculus) PubMed

 7789.

AcpB could provide the hydrolytic activity necessary to transform the nontransportable phosphorylated vitamin B1 present in tissues to a form that can be absorbed by the intracellular pathogen. [AcpB] (Mus musculus) PubMed

 7790.

A-type inclusions phenotype is dependent on the A-type inclusion protein (Atip) and the P4c protein.[Atip & P4c] (Mus musculus) PubMed

 7791.

The first type III PRMT in C. elegans, was identified. (Mus musculus) PubMed

 7792.

heat tolerance function of Gts1p is regulated by Ssa1p and Ssa2p [Gts1p][Ssa1p][Ssa2p] (Mus musculus) PubMed

 7793.

structural basis for recognition of budding yeast (Saccharomyces cerevisiae) CenH3 (called Cse4) by Scm3 [Scm3 & Cse4] (Mus musculus) PubMed

 7794.

Protein kinase C in Neurospora crassa is activated by exogenous diacylglycerol and phorbol esters, and translocates to the plasma membrane from the cytoplasm.[protein kinase C] (Mus musculus) PubMed

 7795.

qSTV11TQ is a rice stripe resistance gene (Mus musculus) PubMed

 7796.

An almost complete homology model of AtoC and of its putative entity as a dimer is constructed for this study, as well as a model of its binding to its target DNA sequence.[AtoC] (Mus musculus) PubMed

 7797.

staphopain A (ScpA) and staphopain B (SspB)secreted from S. aureus degrade collagen and fibrinogen ledaing to clotting impariment and tissue destruction. [ScpA, SspB] (Mus musculus) PubMed

 7798.

There was a predominance of one major haplotype and extreme reduction in genetic diversity of OsAMT1;1 in cultivated rice compared to that in its wild progenitor O. rufipogon. [OsAMT1;1] (Mus musculus) PubMed

 7799.

the regulation of Ecl1 [Ecl1] (Mus musculus) PubMed

 7800.

A cDNA encoding a putative extracellular alpha-L-arabinofuranosidase was cloned from the basidiomycete Coprinopsis cinerea [CcAbf62A] (Mus musculus) PubMed

 7801.

Kip3 clusters kinetochores on the metaphase spindle by tightly regulating kinetochore microtubule lengths.[Kip3] (Mus musculus) PubMed

 7802.

Binding of calmodulin to the regulatory domain induces conformational changes that release the catalytic cleft, activating the kinase and exposing an otherwise inaccessible phosphorylation site, threonine 286.[CaMKII] (Mus musculus) PubMed

 7803.

The PP2A-SUR-6 promotes centriole assembly by protecting ZYG-1 and SAS-5 from degradation. (Mus musculus) PubMed

 7804.

Together, these results may suggest that both PD-1 and Tim-3 are mediators of CD8(+) T cell exhaustion and latency in LAT-expressing herpes simplex virus-1 infection.[LAT] (Mus musculus) PubMed

 7805.

The authors show that the function of Cauliflower mosaic virus viroplasmin in reinitiation depends on physical association with TOR, with viroplasmin-TOR binding being critical for both translation reinitiation and viral fitness.[viroplasmin] (Mus musculus) PubMed

 7806.

The results show that the carboxy-terminus of Orf is involved in nucleic acid recognition and also plays an unexpected role in maintaining structural integrity.[Orf] (Mus musculus) PubMed

 7807.

The types of forces important to binding via a combination of isothermal titration calorimetry (ITC) and computational docking studies that employed rice GID1 (OsGID1), were studied.[OsGID1] (Mus musculus) PubMed

 7808.

TcEF-2 bound with similar affinity to the four P1/P2 ribosomal P proteins of T. cruzi but with reduced affinity to TcP0.[EF-2] (Mus musculus) PubMed

 7809.

The energetic contribution to guanylate kinase substrate binding and the forces underlying ligand recognition, was investigated.[Guanylate kinase] (Mus musculus) PubMed

 7810.

TLN4 is an extensively processed putative metalloproteinase secreted from micronemes. [TLN4] (Mus musculus) PubMed

 7811.

A modification of Clb2, by the C-terminal addition of a Myc12 epitope, causes the loss of one specific mitotic function of Clb2.[Clb2] (Mus musculus) PubMed

 7812.

Data suggest a genetic link between AgSAC6 and AgWAL1 based on the common mutant phenotypes regarding aberrant hyphal growth and endocytosis. [WAL1] (Mus musculus) PubMed

 7813.

These data suggest that the defects in sexual reproduction were caused by the reduction in histone acetylation in the ATP citrate lyase deletion mutants.[ATP citrate lyase] (Mus musculus) PubMed

 7814.

DeltaMoplc2 and DeltaMoplc3 mutants developed multiple appressoria on separate germ tubes of a conidium, indicating that MoPLC2- and MoPLC3-regulated signaling suppresses a feedback loop of a pathway for appressorial development.[plc2 &plc3] (Mus musculus) PubMed

 7815.

The authors propose that in the presence of chitin disaccharide, TfoR sRNA is expressed to activate the translation of tfoX, which leads to the induction of natural competence.[tfoX] (Mus musculus) PubMed

 7816.

Data show that histidine decarboxylase (hdcA)was isolated from a new strain Staphylococcus epidermidis TYH1: [hdcA] (Mus musculus) PubMed

 7817.

proteasomal degradation of Sfp1 is mediated by Blm10 and contributes to the repression of ribosome biogenesis under nutrient depletion.[Sfp1, Blm10] (Mus musculus) PubMed

 7818.

Membrane trafficking and septins function synergistically to maintain the dynamic polarization of Cdc42p during asymmetric growth in yeast.[Cdc42, septin] (Mus musculus) PubMed

 7819.

Accumulation of aggregated polypeptides was strongly decreased by the AAA-protease Pim1/LON.[Pim1] (Mus musculus) PubMed

 7820.

BiP1, predominantly expressed in maturing rice endosperm, acts as not only a chaperone but also a stress sensor protein for ER quality control. (Mus musculus) PubMed

 7821.

The kinetic parameters of carbohydrate oxidation catalyzed by Escherichia coli PQQ-dependent aldose sugar dehydrogenase (ASDH) were determined using various electron acceptors.[ASDH] (Mus musculus) PubMed

 7822.

These results show that ERG20 (farnesyl pyrophosphate synthase) is not required for survival in an infected mouse, but the RAM2-encoded prenyltransferase was critical for growth under both in vitro and in vivo conditions.[RAM2] (Mus musculus) PubMed

 7823.

PkaC2 acts in concert with PkaC1 to support cell wall homeostasis and regulate conidial germination and carbohydrate metabolism, but has limited influence on asexual development (Mus musculus) PubMed

 7824.

C. albicans smt3/smt3 cells displayed defects in growth, morphology, cell separation, nuclear segregation, and chitin deposition, suggesting important roles for sumoylation in cell cycle control.[Smt3] (Mus musculus) PubMed

 7825.

These data suggest that the blue-light receptor MGWC-1 in Magnaporthe oryzae is involved in light-dependent disease suppression during the dark-phase (disease-conducive light condition) immediately after pathogen-host contact.[MGWC-1] (Mus musculus) PubMed

 7826.

Direct kinetic measurements of RNA polymerase II (Pol II) movement across the 9.5-kb GAL10p-VPS13 gene revealed that the elongation rate of polymerase is 24% slower in the absence of Htz1. We provide evidence for two nonexclusive mechanisms. [Htz1] (Mus musculus) PubMed

 7827.

Study results establish elongator protein 3b (ELP3b) as a major negative regulator of rDNA transcription and extend the roles of the Elp3-related proteins to RNAP-I transcription units.[Elongator protein 3b] (Mus musculus) PubMed

 7828.

ProQ does not regulate proP transcription. It may act as an RNA-binding protein to regulate proP translation. [ProQ][ProP] (Mus musculus) PubMed

 7829.

a novel role for the identity of A-Site bound tRNA in RelA-mediated (p)ppGpp synthesis [RelA] (Mus musculus) PubMed

 7830.

Expression of ClpB regulated by CtsR, appears to play a major role in induced thermotolerance and in pathogenesis, as assessed by using the Galleria mellonella virulence model. [clpB, CtsR] (Mus musculus) PubMed

 7831.

janosiThese data confirm the importance of a cation-binding site in BetP, playing a key role in a proposed molecular mechanism of Na(+) and H(+) coupling in betaine-choline-carnitine transporters.[BetP] (Mus musculus) PubMed

 7832.

Diclofenac inhibits respiration by interfering with Rip1p and Cox9p in the respiratory chain, resulting in ROS production that causes cell death. [Rip1, Cox9] (Mus musculus) PubMed

 7833.

findings explain how Gle1(InsP6), Nup159 and Dbp5 collaborate in mRNA export and provide a general mechanism for DEAD-box ATPase regulation by Gle1/eIF4G-like activators [Gle1 & Nup159 & Dbp5] (Mus musculus) PubMed

 7834.

The Ire1-catalyzed phosphoryl-transfer aids disassembly of Ire1 signaling complexes and is a critical component of the unfolded protein response homeostatic feedback loop.(Ire1) (Mus musculus) PubMed

 7835.

The importance of proper Ire1 RNase attenuation is demonstrated by the inability of cells expressing Ire1-D828A to grow under ER stress. (Ire1 RNase ) (Mus musculus) PubMed

 7836.

These data and the corresponding results point to one of Hfq functional structural consequences due to ATP binding and Tyr25Ala mutation.[Hfq] (Mus musculus) PubMed

 7837.

The proteomic data from this study provides direct evidence that the E. coli specific beta-methylthiolation likely occurs when S12 is assembled as part of a ribosomal subunit.[Ribosomal protein S12] (Mus musculus) PubMed

 7838.

Sskp, which encodes a periplasmic chaperone involved in targeting misfolded outer-membrane proteins to the beta-barrel assembly machinery, is required for infections in a murine model of typhoid. [Skp] (Mus musculus) PubMed

 7839.

Hydrodynamic parameters of the holoenzyme indicated that Y. lipolytica cAMP-dependent protein kinase is a dimer of 90 kDa composed of an R subunit of 42 kDa and a C subunit of 39 kDa. [cAMP-dependent protein kinase] (Mus musculus) PubMed

 7840.

Our results show that Clp dependent proteolysis of LexA is conserved in S. aureus and that the NTD may differentially regulate a subset of genes in the SOS regulon. [Clp, LexA] (Mus musculus) PubMed

 7841.

These results show that the Aspergillus niger albA polyketide synthase is responsible for both the production of the spore pigment precursor and a family of naphtho-gamma-pyrones.[albA] (Mus musculus) PubMed

 7842.

This protein is homologous to PfRON2 which has previously been shown to be associated with PfAMA-1, suggesting a similar role for PvRON2.[PvRON2] (Mus musculus) PubMed

 7843.

Prothoracicotropic hormone (PTTH) transcripts exhibit a daily cycling profile in final larval instar. In adult females expression was initially at a nearly constant level in diapausers but decreased quickly in nondiapausers. [prothoracicotropic hormone] (Mus musculus) PubMed

 7844.

study shows how yihU-yshA gene cluster forms a transcriptional unit regulated y by cAMP receptor protein; results show 2 CRP-binding sites on regulatory region of the yihU-yshA operon are required to promote transcriptional activation [CRP, yihU, yshA] (Mus musculus) PubMed

 7845.

FimD-FimC-FimH structure provides unique insights into the pilus subunit incorporation cycle, and captures the first view of a protein transporter in the act of secreting its cognate substrate (Mus musculus) PubMed

 7846.

NLP is also involved in repression of transcription in the inactive variant surface glycoprotein Basic Copy arrays, minichromosomes and procyclin loci (NLP). (Mus musculus) PubMed

 7847.

These results suggest that Crg2 is critical for establishment of early pulmonary infection and for persistence of infection.[Crg2] (Mus musculus) PubMed

 7848.

CiCAP is expressed by Ciona intestinalis hemocytes after lipopolysaccharide challenge. The polypeptide displays a modular structure with similarities to vertebrate CAP-superfamily proteins and to a collagen binding adhesin of Streptococcus mutans. [CiCAP] (Mus musculus) PubMed

 7849.

central conserved domain of Prp8 is related to the catalytic domain of reverse transcriptases [Prp8] (Mus musculus) PubMed

 7850.

crystal structures of ISW1a lacking its ATPase domain both alone and with DNA bound at resolutions of 3.25 A and 3.60 A, respectively; visualization of two different nucleosome-containing remodelling complexes using cryo-electron microscopy [ISW1a] (Mus musculus) PubMed

 7851.

Axs5 is a GH62 alpha-L-arabinofuranosidase specific for arabinoxylan. [Axs5] (Mus musculus) PubMed

 7852.

Structural asymmetry in a trimeric Na+/betaine symporter, BetP, from Corynebacterium glutamicum (BetP) (Mus musculus) PubMed

 7853.

Identification of N-terminal regions of wheat leaf ferredoxin NADP+ oxidoreductase important for interactions with ferredoxin (Mus musculus) PubMed

 7854.

a new 5' exon (exon 1) in the apn1 gene and show that the inactivity of S. pombe Apn1 is due to a nonsense mutation in the fifth codon of this new exon (Mus musculus) PubMed

 7855.

demonstrate that in vitro Stm1 inhibits translation after formation of an 80S complex[Stm1] (Mus musculus) PubMed

 7856.

The authors show that Cse3 type CRISPR-specific endoRNases bind a hairpin structure and residues downstream of the cleavage site within the repetitive segment of cognate CRISPR RNA.[Cse3] (Mus musculus) PubMed

 7857.

The surface-associated subtilisin-like protease SspA induced the secretion of IL-1beta, TNF-alpha, IL-6, CXCL8 and CCL5 by macrophages. [SspA] (Mus musculus) PubMed

 7858.

This study reveals the possible initial structural event that leads to release of the B loop from its prefusion conformation, which is aided by unexpected structural changes within the membrane-distal HA1 domain at low pH.[HA] (Mus musculus) PubMed

 7859.

These results demonstrate the considerable pathogenicity of NA N294S substitution-possessing H5N1 viruses and underscore the importance of monitoring the emergence of the NA N294S mutation in circulating H5N1 viruses.[NA] (Mus musculus) PubMed

 7860.

In addition to salt stress, the cyclophilin OsCYP2 can respond to other types of stresses, such as drought, heat and cold. [CYP2] (Mus musculus) PubMed

 7861.

high resolution crystal structure of SNAC1 (stress-responsive NAC) NAC domain [SNAC1] (Mus musculus) PubMed

 7862.

The N-terminal unstructured domain of yeast ODC functions as a transplantable and replaceable ubiquitin-independent degron (Mus musculus) PubMed

 7863.

Q-motif not only senses the nucleotide state of the helicase but could also stabilize a catalytically competent conformation of the P-loop and other helicase signature motifs [Hera] (Mus musculus) PubMed

 7864.

show that MRB3010 is essential for growth of both procyclic form and bloodstream form life-cycle stages of Trypanosoma brucei[MRB3010] (Mus musculus) PubMed

 7865.

This study showed that extracellular hemicentin-1[Hmcn1] assemble at the cleavage furrow of dividing cells in the C. elegans germline and in preimplantation mouse embryos.[Hmcn1] (Mus musculus) PubMed

 7866.

Dia1 mRNA localizes to the perinuclear endoplasmic reticulum through interactions between Dia1 nascent peptide and Rho-GTP. [Dia1] (Mus musculus) PubMed

 7867.

Characterization of a novel Salmonella Typhimurium chitinase which hydrolyzes chitin, chitooligosaccharides and an N-acetyllactosamine conjugate (Mus musculus) PubMed

 7868.

SpnA is a novel group A streptococcal virulence factor. [SpnA] (Mus musculus) PubMed

 7869.

A high-affinity adenosine kinase from Anopheles gambiae. (Mus musculus) PubMed

 7870.

Substitution of the highly conserved catalytic Thr132 into Ser or Ala of NPP completely abolished enzyme activity. [NPP] (Mus musculus) PubMed

 7871.

CD8 T cell responses to T. annula...were shown to be focused entirely on a single dominant epitope in one antigen, Ta9. (Mus musculus) PubMed

 7872.

The authors conclude that the HA-33/HA-17 arm is not necessarily required for, but facilitates, transport of botulinum toxin complexes.[HA-33 & HA-17] (Mus musculus) PubMed

 7873.

These show that the mean absorbance values for binding to the HCMV UL118/UL119-encoded FcgammaR were higher for IgG1 expressing the GM 3 allotype than for those expressing the allelic GM 1,2,17 determinants (p = 0.0005).[UL118, UL119] (Mus musculus) PubMed

 7874.

the possible roles of the budding yeast Smc5/6 complex in maintaining appropriate chromosome end-structures allowing cell survival in absence of telomerase[Smc5][Smc6] (Mus musculus) PubMed

 7875.

The effect of the ret1-1 mutation on the secretome, the glycosylation patterns and locations of the secretory proteins, were studied.[Ret1-1] (Mus musculus) PubMed

 7876.

IFE-1 is required for efficient expression of some sperm-specific proteins.[IFE-1] (Mus musculus) PubMed

 7877.

studies establish XalphaCP2 as a novel cytoplasmic polyadenylation trans factor, indicate that C-rich sequences can function as noncanonical cytoplasmic polyadenylation elements[alphaCP2] (Mus musculus) PubMed

 7878.

The V. cholerae CqsA/CqsS system is less stringent and does not discriminate well between ligands.[CqsA/CqsS] (Mus musculus) PubMed

 7879.

The authors identify a novel Lymantria dispar multicapsid nucleopolyhedrovirus apoptosis suppressor gene, apsup, which functions to suppress apoptosis induced in Ld652Y cells.[apsup] (Mus musculus) PubMed

 7880.

The authors demonstrated that the NS1 protein interacts specifically with NP and not the polymerase subunits.[NS1 & NP] (Mus musculus) PubMed

 7881.

In a trans-complementation experiment with a movement-defective tomato mosaic virus, pC6 of rice grassy stunt virus facilitated intercellular transport of the virus.[pC6] (Mus musculus) PubMed

 7882.

These results provide support for a role for the extreme amino terminus of NS3 in the late stages of virus growth in mammalian cells, plausibly in egress.[NS3] (Mus musculus) PubMed

 7883.

The authors show that the mouse cytomegalovirus m155 open reading frame is required for the posttranscriptional inhibition of CD40 expression in infected antigen-presenting cells. (Mus musculus) PubMed

 7884.

V. harveyi CqsA/CqsS system is exquisitely selective for (Z)-3-aminoundec-2-en-4-one. [CqsA,CqsS] (Mus musculus) PubMed

 7885.

CaBP1 regulates voltage-dependent inactivation and activation of Ca(V)1.2 (L-type) calcium channels [CaBP1] (Mus musculus) PubMed

 7886.

characterization of a hyperthermostable Mn-superoxide dismutase from Thermus thermophilus HB27 (Mus musculus) PubMed

 7887.

crystallization and preliminary X-ray analysis of SaMazF; crystals of S. aureus MazF (SaMazF) were grown in space group P2(1)2(1)2(1);crystals diffracted to 2.1A resolution and are likely to contain two SaMazF dimers in the asymmetric unit [MazF] (Mus musculus) PubMed

 7888.

The Ndc80 loop region has an important role in the conversion from lateral to end-on attachment, a crucial maturation step of kinetochore-microtubule interaction. (Mus musculus) PubMed

 7889.

analysis of the mechanism of action of TbREL1 inhibitors [TbREL1] (Mus musculus) PubMed

 7890.

ATF3 interacts with HTLV-I bZIP factor and promotes proliferation of ATL cells. (Mus musculus) PubMed

 7891.

It is demonstrated that the inter-subspecific differentiation of SD1 contributes height difference between indica and japonica [SD-1] (Mus musculus) PubMed

 7892.

characterization of the Streptococcus pneumoniae RrgB pilus backbone D1 domain [RrgB] (Mus musculus) PubMed

 7893.

Integral membrane cargo proteins become polarized by directed vesicle traffic given the experimentally determined rates of vesicle traffic and diffusion but cannot effectively polarize the more rapidly diffusing Cdc42p. (Mus musculus) PubMed

 7894.

PSS1 is a novel member of the kinesin-1 family essential for male meiotic chromosomal dynamics, male gametogenesis, and anther dehiscence in rice. (Mus musculus) PubMed

 7895.

PDIL1;1 localizes to the ER lumen and facilitates the oxidative folding of vacuole-targeted storage proteins. PDIL2;3 localizes on the protein body surface and promotes the specific localization of crP10 in the protein body core. [PDIL1;1 & PDIL2;3] (Mus musculus) PubMed

 7896.

SUB1A confers drought tolerance to rice, increases ABA responsiveness, and enhances oxidative stress tolerance. (Mus musculus) PubMed

 7897.

expression of Paracoccidioides brasiliensis alternative oxidase is developmentally regulated through mycelium to yeast differentiation. [AOX] (Mus musculus) PubMed

 7898.

M-Enk expression after complete dorsal rhizotomy is mainly on the lateral side in lamina II of the sprinal cord. [M-Enk] (Mus musculus) PubMed

 7899.

Dendroaspis natriuretic peptide was detected in heart, kidney, liver, brain, and plasma of New Zealand rabbits. It may help to maintain sodium and fluid volume homeostasis in a healthy cardio-renal environment. (Mus musculus) PubMed

 7900.

Vaccinia virus VH1 is essential for dephosphorylation of STAT1 at tyrosine 701 [VH1] (Mus musculus) PubMed

 7901.

OmpD, the most abundant porin in Salmonella enterica serovar Typhimurium, facilitates uptake of hydrogen peroxide (HO) and that its expression is negatively regulated by ArcA upon peroxide exposure. [OmpD] (Mus musculus) PubMed

 7902.

Candida glabrata Pdr1 combines features of Saccharomyces cerevisae Pdr1 and Pdr3 to produce a transcription factor with chimeric regulatory properties. [CgPdr1] (Mus musculus) PubMed

 7903.

Hap43 executes its function by becoming a transcriptional repressor and accumulating in the nucleus in response to iron deprivation. [Hap43] (Mus musculus) PubMed

 7904.

the EndoG homologue, NucA, is not involved in cell death, but it plays a role in the DNA-damaging response in Aspergillus nidulans. [nucA] (Mus musculus) PubMed

 7905.

MLC2 is associated with myosin D via its calmodulin (CaM)-like domain and anchored to the plasma membrane of T. gondii via its N-terminal extension [MyoD, MLC2] (Mus musculus) PubMed

 7906.

JNK expression was elevated in cochlea after exposure to intense noise. (Mus musculus) PubMed

 7907.

miR-92 is a critical regulator of endoderm formation and left-right asymmetry during early zebrafish development.[miR-92 microRNA] (Mus musculus) PubMed

 7908.

These studies support a role for AgAQP1 in water homeostasis during blood feeding and humidity adaptation of A. gambiae, a major mosquito vector of human malaria in sub-Saharan Africa. (Mus musculus) PubMed

 7909.

ATP binding to hemoglobin response gene 1 protein is necessary for regulation of the mating type locus in Candida albicans [Hbr1] (Mus musculus) PubMed

 7910.

A galactose-stable deletion derivative of Mig2 caused a strong Mig phenotype, confirming that galactose induction of the GAL1 gene requires the degradation of the repressor Mig2.[GAL1; Mig2] (Mus musculus) PubMed

 7911.

Genetic analysis of the cyp-35B1 promoter showed both DAF-16 and HSF-1 are direct regulators.[HSF-1, cuyp-35B1] (Mus musculus) PubMed

 7912.

The interaction between HrpB2, a small protein secreted by the Xanthomonas citri subsp. citri type III secretion system, and the cytosolic domain of the inner membrane protein HrcU, is characterized.[HrpB2, HrcU] (Mus musculus) PubMed

 7913.

An evaluation of two independent domains in the monomeric protein NusG is reported.[NusG] (Mus musculus) PubMed

 7914.

The single-particle cryo-EM structure of the Sec YEG complex in a membrane environment is determined. [SecY, SecE, and SecG] (Mus musculus) PubMed

 7915.

Multiple regions of Bud3p ensure efficient targeting of Bud3p to the bud neck in the assembly of the axial landmark and distinct domains of Bud3p are involved in axial bud-site selection and other cellular processes.[Bud3] (Mus musculus) PubMed

 7916.

Pba1-Pba2 requires a previously overlooked C-terminal hydrophobic-tyrosine-X (HbYX) motif for function. [Pba1 & Pba2] (Mus musculus) PubMed

 7917.

a single point mutation (Ile219-->Lys; a base pair change) in the glycan receptor-binding site (RBS) of a representative 2009 H1N1 influenza A virus, A/California/04/09 or CA04/09, quantitatively increases its human receptor-binding affinity (Mus musculus) PubMed

 7918.

The COOH-terminal truncated form of p17 (p17Delta36) induced activation of the PI3K/Akt pathway by maintaining PTEN in an inactive phosphorylated form.[p17] (Mus musculus) PubMed

 7919.

These data therefore demonstrate that at least these two CgPDR1-dependent and -upregulated genes contribute to the enhanced virulence of C. glabrata that acquired azole resistance.[CgPDR1] (Mus musculus) PubMed

 7920.

Motif conservation analysis revealed that nine FlbB orthologs belonging to the Eurotiales order contained a motif in the central region that could mediate interaction with FlbE.[FlbB] (Mus musculus) PubMed

 7921.

the avian-like low-pH stability of sialidase activity in the 1918 pandemic virus NA contributes to the viral replication efficiency [NA, strain 1918] (Mus musculus) PubMed

 7922.

Ecs is essential for staphylococcal virulence and antimicrobial resistance probably since the transport function of Ecs is essential for the normal structure and function of the cell wall [Ecs] (Mus musculus) PubMed

 7923.

analysis of genomic CeMyoD binding sites revealed and cross validated by ChIP-Chip and ChIP-Seq techniques [MyoD] (Mus musculus) PubMed

 7924.

TbUNC119 and its binding protein complex are essential for propagation, motility, and morphogenesis of Trypanosoma brucei procyclic form cells [TbUNC119] (Mus musculus) PubMed

 7925.

SNX-6 is enriched on phagosome surfaces and promotes the fusion of early endosomes and lysosomes to phagosomes. (Mus musculus) PubMed

 7926.

The N-terminal domain of Ama1p interacts with 2 motifs within Cdc20p during meiosis. [2 genes] (Mus musculus) PubMed

 7927.

ewes with genotype BB had 0.58 (P < 0.01) lambs more than those with AA in Hu sheep[ inhibin beta B] (Mus musculus) PubMed

 7928.

Actinobacillus pleuropneumoniae HMW1C-like glycosyltransferase mediates N-linked glycosylation of the Haemophilus influenzae HMW1 adhesin [HMW1] (Mus musculus) PubMed

 7929.

findings indicate that a specific factor in royal jelly, royalactin, drives queen development through an Egfr-mediated signalling pathway [royalactin] (Mus musculus) PubMed

 7930.

folding of the 790-residue membrane protein BamA, which is the core component of the Escherichia coli outer membrane protein assembly machinery [BamA] (Mus musculus) PubMed

 7931.

Protein binding and unbinding of the Min proteins, MinC, MinD, and MinE functions to propagate the pole-to-pole oscillation of Min proteins involved in cell division. [3 genes] (Mus musculus) PubMed

 7932.

The 1.8 A crystal structure of Cass2, an integron-associated protein derived from an environmental V. cholerae, is reported.[Cass2] (Mus musculus) PubMed

 7933.

New ompA gene sequences different from L2/434 reference strain and from the L2b variant were found including point mutations at VS1 domain A294T & C472G, and VS4 C1012T. (Mus musculus) PubMed

 7934.

The EndA structure reveals a DRGH (Asp-Arg-Gly-His) motif-containing betabetaalpha-metal finger catalytic core augmented by an interesting 'finger-loop' interruption of the active site alpha-helix (EndA). (Mus musculus) PubMed

 7935.

The functional YFP-GmtA (GDP-mannose transporter)Golgi reporter shows the GPTase SrgC has an important role in maintaining the integrity of Golgi-like structures in A. niger. [GmtA, SrgC] (Mus musculus) PubMed

 7936.

AeSCP-2 expression knockdown in early instar larvae resulted in detectable phenotypes of the expression deficiency such as high mortality, lowered fertility, and distorted sex ratio.[AeSCP-2] (Mus musculus) PubMed

 7937.

Data suggest that Nato3 is a direct target of Foxa2, a transcription activator and effector of Sonic hedgehog, the hallmark regulator of neural tube floor plate induction and spinal cord development [Nato3]. (Mus musculus) PubMed

 7938.

Agr and SaeRS have roles in the pathogenesis of CA-MRSA USA300 infection [SaeR, SaeS] (Mus musculus) PubMed

 7939.

CDP1 and CYG56 regulation is involved in the NH4+ signalling pathway. [2 genes] (Mus musculus) PubMed

 7940.

results suggest that metabotropic glutamate receptors I/II regulate the release of glutamate, likely from bipolar cells, that in turn activates GABA release from amacrine cells via a transporter mediated process[metabotropic glutamate receptor 2] (Mus musculus) PubMed

 7941.

The effects of 6 mutations on CpxP function in physiological stress are reported.[CpxP] (Mus musculus) PubMed

 7942.

SubAB induced small bowel hemorrhage and inflammatory changes.[SubA, subB] (Mus musculus) PubMed

 7943.

dentipain contributes to the virulence of T. denticola [dentipain] (Mus musculus) PubMed

 7944.

Cx50 is phosphorylated in vivo by PKA at Ser-395, which promotes increased dye permeability of Cx50 channels and plays an important role in metabolic coupling and transport in lens fibers [PKA] (Mus musculus) PubMed

 7945.

These results demonstrate that during periods of hydrogen peroxide stress, the induction of YaaA is a critical device to suppress intracellular iron levels; it thereby attenuates the Fenton reaction and the DNA damage that would otherwise result.[YaaA] (Mus musculus) PubMed

 7946.

analysis of how the CtrA and CtrB transporters-PCP-OPX multiprotein complex functions to export CPS across the cell envelope [CtrA, CtrB] (Mus musculus) PubMed

 7947.

the kinetic mechanism for the AlkA-catalyzed excision of hypoxanthine [AlkA] (Mus musculus) PubMed

 7948.

Despite sequence and structural similarity with spermidine synthases from other organisms, a novel C-terminal beta-sheet and differences in the catalytic site of aminopropyltransferase were observed. [aminopropyltransferase TAAPT] (Mus musculus) PubMed

 7949.

Tpk1 and Tpk2 isoforms regulate pseudohyphal development, biofilm structure, cell aggregation and adhesins expression. [Tpk1, Tpk2] (Mus musculus) PubMed

 7950.

The role of WalRK and DacB in the remodeling of cell walls during division are reported.[WalRK; DacB] (Mus musculus) PubMed

 7951.

Mutation in the COX5 gene alters utilization of amino acids as carbon source and ethanol formation. [Cox5] (Mus musculus) PubMed

 7952.

RpoE and RpoS regulated gene expression during hyperosmotic stress. [RpoE] (Mus musculus) PubMed

 7953.

Structural analyses of mannosylglycerate synthase complexes not only provide insight into metal coordination but also how lactate can function as an alternative acceptor to glycerate[mannosylglycerate synthase] (Mus musculus) PubMed

 7954.

Oct3/4 initiates its own negative autoregulation through Cdx1 up-regulation to begin the repression of pluripotency in preparation for the onset of gastrulation and germ layer differentiation.[oct3/4, Xenopus laevis] (Mus musculus) PubMed

 7955.

This work further clarifies the coordinated role of MarA and Rob in regulating the expression of the outer membrane porins.[MarA; Rob] (Mus musculus) PubMed

 7956.

analysis of the C-terminal domain of a tyrosyl-tRNA synthetase that functions in group I intron splicing [TyrR, TyrS] (Mus musculus) PubMed

 7957.

CCZ1, MON1 and YPT7 proteins are required for the cytoplasm to vacuole targeting pathway, and for nutrient starvationinduced non-specific macroautophagy in the methylotrophic yeast P. pastoris. [CCZ1, MON1,YPT7] (Mus musculus) PubMed

 7958.

MyoB is essential for chitin deposition at nascent septation sites but not actin localization. [MyoB] (Mus musculus) PubMed

 7959.

Pdr1 activates a broad repertoire of genes, specific mutations activates discrete subsets of this repertoire. [Pdr1] (Mus musculus) PubMed

 7960.

In the distal germline, where MPK-1 is not activated, TRA-1 represses the male fate as NOS-3 functions in translational repression leading to inactivation of the FEM-CUL-2 ubiquitin ligase. (Mus musculus) PubMed

 7961.

a bicarbonate transport metabolon proposed for the interaction between CAII and NBCe1 does not work at least in Xenopus oocytes [NBCe1/SLC4a4] (Mus musculus) PubMed

 7962.

Inactivation of rbp1 led to a great reduction in the acquired chill-light tolerance, while ectopic expression of rbp1 enabled the cyanobacterium to survive the chill-light stress without preconditioning.[rbp1] (Mus musculus) PubMed

 7963.

All-atom molecular dynamics simulations were used to to obtain atomic-scale data on the effects of membrane interface lipid composition on PMP1 structure and tilt.[PMP1] (Mus musculus) PubMed

 7964.

The provide evidence that a similar yet distinct process is taking place: the motor domain is precluding the tail domain from binding to cortical Num1. (Num1) (Mus musculus) PubMed

 7965.

The recombinant form of UDP-galactopyranose mutase (UGM) was obtained in a soluble and active form and characterized. [UGM] (Mus musculus) PubMed

 7966.

The distribution of HU in Caulobacter crescentus was investigated using a combination of super-resolution fluorescence imaging and spatial point statistics.[HU protein] (Mus musculus) PubMed

 7967.

App1 is upregulated during glucose starvation. [App1] (Mus musculus) PubMed

 7968.

the mechanism of penicillin-binding protein-catalyzed cross-linking of the bacterial cell wall [PBP 1b] (Mus musculus) PubMed

 7969.

Depletion of mitochondrial acyl carrier protein in bloodstream-form causes a kinetoplast segregation defect. [ACP] (Mus musculus) PubMed

 7970.

The structure of this functionally important region of calponin and its interaction with actin and calmodulin at amino-acid resolution, was mapped.[F-actin] (Mus musculus) PubMed

 7971.

The authors report that expression of human herpesvirus 5 ORF94 protein leads to decreased 2',5'-oligoadenylate synthetase (OAS) expression in transfected cells with and without interferon stimulation.[ORF94] (Mus musculus) PubMed

 7972.

Inactivation of atlS resulted in formation of long chains by the cells, markedly decreased autolytic capacity, poor biofilm formation, diminished tolerance of acid and oxidative stress, and decreased production of extracellular DNA (eDNA).[atlS] (Mus musculus) PubMed

 7973.

a novel C. elegans longevity factor, SLCF-1, whose inactivation increased lifespan in worms (Mus musculus) PubMed

 7974.

infection with East-Asian-type CagA H. pylori was more closely associated with gastric mucosal atrophy and gastric cancer than infection with non-East-Asian-type CagA H. pylori [CagA] (Mus musculus) PubMed

 7975.

The study identified the embryonic isoform laminin-associated polypeptide 2 gamma, which was downregulated during development similarly to laminin-associated polypeptide 2 omega. [laminin-associated polypeptide 2] (Mus musculus) PubMed

 7976.

Data show that Kluyveromyces lactis KlGalpha interacts with the adaptor protein KlSte50p [Ste50]. (Mus musculus) PubMed

 7977.

These results suggest that the protein kinase B gene homologue pkbR1 mutant has defects in a system that changes the physiological dynamics in the prestalk cell region of a finger [pkbR1]. (Mus musculus) PubMed

 7978.

Data show that the C. neoformans wsp1 mutant exhibited defects in growth, cytokinesis, chitin distribution, and endocytosis and exocytosis, and whose ability to cause lethal infection in a murine model of cryptococcosis was also attenuated. (Mus musculus) PubMed

 7979.

Studies on the reaction mechanism revealed that PpoA uses two different heme domains to catalyze two subsequent reactions. Initially, the fatty acid substrate is dioxygenated at C8, yielding an 8-hydroperoxy fatty acid at the N-terminal domain. [PpoA] (Mus musculus) PubMed

 7980.

The SmQnrR protein is a transcriptional repressor for the contiguous Smqnr and SmtcrA genes, and SmQnrR is a negative regulator of SmqnrR-SmtcrA operon expression.[QnrR] (Mus musculus) PubMed

 7981.

CG-1A promotes condensation formation and cartilage development; knockdown of CG-1A inhibits the formation of skeletal elements CG-1A causes the aggregation of precartilage cells. [CG-1A] (Mus musculus) PubMed

 7982.

The authors demonstrated by performing genetic studies as well as by using semipurified molecules that, in contrast to a previous report, both of these genes are required for optimum mutacin IV activity.[nlmA & nlmB] (Mus musculus) PubMed

 7983.

Clusters of polarized photons indicated an anisotropy decay of single actomyosin motors of ~9s during muscle contraction.[Actomyosin] (Mus musculus) PubMed

 7984.

fur mutations can affect metronidazole susceptibility by altering the balance among Fur's several competing activities.[fur] (Mus musculus) PubMed

 7985.

[KdpDE]- important virulence regulator coordinating external K+ sensing and Agr signaling during pathogenesis (Mus musculus) PubMed

 7986.

FbsA protein is composed of alpha helices predominantly and random coils to a lesser extent. (Mus musculus) PubMed

 7987.

Ccr4-Not has previously unrealized functional connections to the mRNA processing/export pathway.[Ccr4] (Mus musculus) PubMed

 7988.

These data support a new model of NS1 regulation in which the RNA binding domain remains dimeric throughout infection, while the effector domain switches between several quaternary states in order to expand its functional space.[NS1] (Mus musculus) PubMed

 7989.

LitR caused by some photodependent mechanism induces the expression of TT_P0055 protein, which serves as a transcriptional activator for the crtB operon and hence causes the expression of carotenoid biosynthesis.[LitR] (Mus musculus) PubMed

 7990.

These studies support the model that CidA and LrgA proteins are bacterial holin-/antiholin-like proteins that function to control cell death and lysis during biofilm development.[CidA] (Mus musculus) PubMed

 7991.

Non-binding inhibitory antibodies reacted highly against the C-terminal end of the VAR2CSA molecule especially the highly polymorphic DBL6epsilon domain.[VAR2CSA] (Mus musculus) PubMed

 7992.

In this study, relevant nucleotides of the casA regulatory region that mediate its LeuO transcriptional activation were identified.[LeuO & CasA] (Mus musculus) PubMed

 7993.

a novel role for Rif1 in assisting the essential telomere protection function of the CST complex [RIF1, strain not found] (Mus musculus) PubMed

 7994.

the bioinformatics data showing an unexpected similarity between NDM-1 and beta-lactamase II from Erythrobacter litoralis [NDM-1][ElBla2] (Mus musculus) PubMed

 7995.

reaction mechanism involving different barrier energies [MutY] (Mus musculus) PubMed

 7996.

In vivo, comparison of the Streptomyces lividans wild type and DeltaCsnR strains using beta-lactamase reporter genes showed that CsnR represses the expression of csnA and of its own gene.[CsnR & CsnA] (Mus musculus) PubMed

 7997.

PAIR3 is required for bouquet formation, homologous pairing, normal recombination, and synaptonemal complex installation; PAIR3 localizes to the chromosome axis and is required for normal binding of PAIR2 to chromosome [PAIR3] (Mus musculus) PubMed

 7998.

The authors have also shown that both MGT and SgtA interact with PBP2 and other enzymes involved in cell wall synthesis in a bacterial two-hybrid assay.[MGT & SgtA] (Mus musculus) PubMed

 7999.

role of the cofactor pyridoxal-5'-phosphate and its binding domain in stability and subunit assembly of phosphoserine aminotransferase [PSAT] (Mus musculus) PubMed

 8000.

Two mitogen activated kinase kinase genes, MKK1 (Tb927.3.4860) and MKK5 (Tb927.10.5270), are not essential in the pathogenic bloodstream stage of Trypanosoma brucei, either in vitro or in vivo [MKK1, MKK5] (Mus musculus) PubMed

 8001.

Pga1 triggers germination in response to carbon sources and affects negatively resistance to different stress conditions. [Pga1] (Mus musculus) PubMed

 8002.

at the entrance of the death phase carbon-metabolizing enzymes [such as the TCA cycle enzymes Mqo2 (malate: quinone oxidoreductase) and FumC/CitG (fumarate hydratase)] are carbonylated to a larger extent in the clpC mutant.[clpC] (Mus musculus) PubMed

 8003.

Nma is involved in apoptosis but not in stress adaptation.[Nma] (Mus musculus) PubMed

 8004.

SOX2 is a novel flavin-dependent sulfhydryl oxidase with good pH and temperature stability. [SOX2] (Mus musculus) PubMed

 8005.

crystal structure of Thermus thermophilus SecDF at 3.3 A resolution, revealing a pseudo-symmetrical, 12-helix transmembrane domain belonging to the RND superfamily and two major periplasmic domains, P1 and P4 [secDF] (Mus musculus) PubMed

 8006.

alternative splicing of Saccharomyces cerevisiae SRC1 pre-mRNA is promoted by the conserved ubiquitin-like protein Hub1[Hub1] (Mus musculus) PubMed

 8007.

These data suggest an early co-circulation of genetically distinct A/HNINv variants and emphasize the importance of a close molecular surveillance to detect rapidly the spread of new viral variants and to define their epidemiological impact. (Mus musculus) PubMed

 8008.

We show here that co-expression of PpRSL1 and PpRSL2 is sufficient to transform gametophore cells into rhizoid cells, indicating that PpRSL1 and PpRSL2 expression is sufficient for rhizoid system development. [RSL1,RSL2] (Mus musculus) PubMed

 8009.

AGL11 is the major functional candidate gene for seedlessness. [AGL11] (Mus musculus) PubMed

 8010.

Cell-cycle-dependent localization of human cytomegalovirus UL83 phosphoprotein in the nucleolus and modulation of viral gene expression in human embryo fibroblasts in vitro (Mus musculus) PubMed

 8011.

In this study, plate assay revealed that Xanthomonas campestris pv. campestris possesses pectin methylesterase activity encoded by pmeA and that its expression is controlled by Clp and RpfF.[pmeA] (Mus musculus) PubMed

 8012.

Constitutive activation of GNA1 or GNA3 in the absence of ENVOY leads to constitutive G-alpha activation in darkness. [ENVOY, GNA1, GNA3] (Mus musculus) PubMed

 8013.

This study revealed that a single BRC motif in BRCA2is sufficient to bind to RAD51 paralogues.[BRCA2 & RAD51] (Mus musculus) PubMed

 8014.

Ku80 gene deletion leads to genomic instability. [Ku80] (Mus musculus) PubMed

 8015.

Noise exposure triggered activation of caspase 3 in apoptic hair cells. (Mus musculus) PubMed

 8016.

These results extend to A. thaliana alpha(5) the range of HcPro-interacting proteasomal subunits, and suggest that HcPro may modulate its associated RNase activity which may contribute to an antiviral response.[HcPro] (Mus musculus) PubMed

 8017.

Report the relationship between infections of HPV16 EP variants and cervical squamous cell carcinoma in young Chinese women. (Mus musculus) PubMed

 8018.

Uremic serum enabled NF-kappaB p65 nuclear translocation and increased NF-kappaB DNA binding activity in cultured aortic endothelial cells. (Mus musculus) PubMed

 8019.

The soluble periplasmic domain of CcmE demonstrated no affinity for the Zn- or Sn-containing protoporphyrins and low affinity for Mn(ii)-protoporphyrin IX. [CcmE] (Mus musculus) PubMed

 8020.

BgsB is a glucosyltransferase that synthesizes monoglucosyldiacylglycerol. Its inactivation profoundly affects cell membrane composition and has secondary effects on lipoteichoic acid biosynthesis.[BgsB] (Mus musculus) PubMed

 8021.

Rum1 encodes a canonical Aux/IAA protein that is required for the initiation of embryonic seminal and post-embryonic lateral root initiation in primary roots of maize. [RUM1] (Mus musculus) PubMed

 8022.

A patch of conserved surface residues contributed by both IFT25 and IFT27 is found adjacent to the GTP-binding site and could mediate the binding to other IFT proteins as well as to a potential GTPase-activating protein.[IFT25 & IFT27] (Mus musculus) PubMed

 8023.

Iodotyrosine dehalogenase-1 was found to be expressed during gastrulation to neurulation in developing chick embryo and was postulated to be a regulator of cell specific deiodination involved in iodine turnover. [DEHAL1] (Mus musculus) PubMed

 8024.

Phenotypic analyses following titration of EzrA levels in Staphylococcus aureus have shown that the protein is required for peptidoglycan synthesis as well as for assembly of the divisome at the midcell and cytokinesis.[EzrA] (Mus musculus) PubMed

 8025.

The authors show that Bca1 controls an early step in complex III assembly and that the supra-molecular organization of Bca1 is dependent upon the assembly level of complex III.[Bca1] (Mus musculus) PubMed

 8026.

The ZC3H18 gene is not essential in bloodstream forms, but in an in vitro model of differentiation, depletion of ZC3H18 delayed the transformation of bloodstream-form trypanosomes to the procyclic form that grows in the Tsetse fly.[ZC3H18] (Mus musculus) PubMed

 8027.

Intraamniotic IL-1alpha causes an acute detrimental inflammatory response in the ileum and a disturbed balance between T-effector and FoxP3+ cells may contribute to this process.[IL-1alpha] (Mus musculus) PubMed

 8028.

how the combination of several pivotal parameters can all lead to strand switches during DNA synthesis by HIV-1 RT was studied. [HIV-1 reverse transcriptase] (Mus musculus) PubMed

 8029.

The crystal structures of apo Os4BGlu12, and its complexes with 2,4-dinitrophenyl-2-deoxyl-2-fluoroglucoside (DNP2FG) and 2-deoxy-2-fluoroglucose (G2F) were solved at 2.50, 2.45 and 2.40A resolution, respectively. [Os4BGlu12] (Mus musculus) PubMed

 8030.

The functional role of GlLa in Giardiavirus-internal ribosome entry site mediated translation in Giardia, was studied.[GlLa] (Mus musculus) PubMed

 8031.

The novel cGMP/PKG/ROS/calmodulin/CaMKII signaling pathway may regulate cardiomyocyte excitability by opening K(ATP) channels and contribute to cardiac protection against ischemia-reperfusion injury.[CaMKII] (Mus musculus) PubMed

 8032.

These findings suggest that the SmeAB pump plays an important role in nodulation competitiveness by mediating resistance toward antimicrobial compounds produced by the host plant.[SmeAB] (Mus musculus) PubMed

 8033.

Complementation of Deltacnb parasites with CnB restored thermotolerance and infectivity in both macrophages and animal models.[CnB] (Mus musculus) PubMed

 8034.

In parasites expressing the DM10 domain of TcNDPK2 fused with green fluorescent protein, the fluorescence was localized in cytoskeleton and flagellum with an identical pattern to TcNDPK2.[NDPK2] (Mus musculus) PubMed

 8035.

AtfA is permanently localized in the nucleus, while SakA accumulates in the nucleus in response to oxidative or osmotic stress signals or during normal spore development, where it physically interacts with AtfA.[SakA & AtfA] (Mus musculus) PubMed

 8036.

Data suggest a dual regulation in which XESR5 produces a competent area for mesoderm formation by suppressing the gene expression of XESR1, while XESR1 sharpens the boundary of Xbra expressio: [XESR5] (Mus musculus) PubMed

 8037.

crystal structure of BamD from the thermophilic bacteria Rhodothermus marinus refined to 2.15 A resolution is reported. [BamD] (Mus musculus) PubMed

 8038.

SteelyA produces 4-methyl-5-pentylbenzene-1,3-diol and induces spore maturation. [SteelyA] (Mus musculus) PubMed

 8039.

The alpha-glucuronidase Agu1 is a member of a novel glycoside hydrolase family. [Agu1] (Mus musculus) PubMed

 8040.

In the chick embryo, Ngn3 independently controls epithelium delamination and differentiation programs. [Ngn3] (Mus musculus) PubMed

 8041.

Data show that three isolated genes: Defender Against Cell Death (Dad1), Polyubiquitin II (UbII) and Ferritin Heavy chain (fth1), are implicated in Programmed Cell Death (PCD)[UBII] (Mus musculus) PubMed

 8042.

To understand the molecular mechanism of translocation, the molecular motions of EF-G were examined in solution by means of molecular dynamics simulations.[EF-G] (Mus musculus) PubMed

 8043.

The extent of alpha-helical secondary structure coincided well, lending support for the two-stage model for membrane protein folding. [disulfide bond forming protein B] (Mus musculus) PubMed

 8044.

Determined is the structure of the S. cerevisiae Nup133 C-terminal helical domain at 1.9 A resolution. [Nup133] (Mus musculus) PubMed

 8045.

The sensitivity of [SWI+] to the activity of Hsp70 chaperone machinery may serve a regulatory role, keeping this prion in an easily-lost, meta-stable state. [Swi1] (Mus musculus) PubMed

 8046.

results indicate NP swine-origin influenza virus(S-OIV)requires early start codon and V313 residue for optimal function-characteristics required for strong compatibility between S-OIV polymerase subunits and its indigenous NP over other strains [NP] (Mus musculus) PubMed

 8047.

BC12/GDD1 is a kinesin-like protein with transcription regulation activity that mediates cell elongation by regulating the GA biosynthesis pathway. [GDD1] (Mus musculus) PubMed

 8048.

AGO104 is required for proper chromatin condensation during meiosis, and acts to repress germ cell fate in somatic tissues. (Mus musculus) PubMed

 8049.

vt2 plays a significant role in axillary meristem formation during inflorescence development in maize. [vt2] (Mus musculus) PubMed

 8050.

The two-pore K+ channels TPKa and TPKb are localized to different types of vacuoles. (Mus musculus) PubMed

 8051.

The study reports the solution structure of a cyanovirin-N homolog protein (CVNH) from Gibberella zea, GzCVNH, that shares 30% sequence identity with cyanovirin-N. [GzCVNH] (Mus musculus) PubMed

 8052.

describe a novel Plasmodium vivax tryptophan-rich protein named PvTRAg33.5. It is expressed by blood stage(s) of the parasite and its gene contains two exons.[PvTRAg33.5] (Mus musculus) PubMed

 8053.

Flounder growth hormone-releasing hormone (GHRH) plays roles in the bidirectional communication network between growth and immunity in fish. (Mus musculus) PubMed

 8054.

results suggests that CBP1 expression is repressed during vegetative growth; transcriptional regulatory mechanism of CBP1 is discussed [CBP1] (Mus musculus) PubMed

 8055.

MoVam7, like MoSec22, is a component of the SNARE complex whose functions in vacuole assembly also underlies the growth, conidiation, appressorium formation, and pathogenicity of M. oryzae.[MoVam7] (Mus musculus) PubMed

 8056.

Individually expressed HSV-1 R1 (ICP6) shares, with HSV-2 R1, the ability to bind caspase-8 and to protect cells against death receptor-induced apoptosis.[ICP6] (Mus musculus) PubMed

 8057.

Individually expressed HSV-1 R1 (ICP6) shares, with HSV-2 R1, the ability to bind caspase-8 and to protect cells against death receptor-induced apoptosis.[ICP10] (Mus musculus) PubMed

 8058.

Txl1 and Txc1 are proteasome co-factors connected with oxidative stress. [Txc1] (Mus musculus) PubMed

 8059.

The TgVTC2 mutant showed dramatically reduced polyphosphate accumulation, a defect restored by introduction of TgVTC2 to the mutant [TgVTC2] (Mus musculus) PubMed

 8060.

MADS3 regulates male reproductive development at least in part through regulating ROS homeostasis. [MADS3] (Mus musculus) PubMed

 8061.

Results suggest that PTB/PID-containing Ci-Noto4 is essential for midline intercalation of notochord cells in embryos: [Noto4] (Mus musculus) PubMed

 8062.

A C2 domain protein kinase initiates phagocytosis in the protozoan parasite Entamoeba histolytica. (Mus musculus) PubMed

 8063.

Mutation of the staphylococcal accessory regulator limits the accumulation of alpha-toxin and phenol-soluble modulins in Staphylococcus aureus isolates of the USA300 clonal lineage.[sarA] (Mus musculus) PubMed

 8064.

crystals of ThiM belonged to the primitive space group P1, with unit-cell parameters a = 62.06, b = 62.40, c = 107.82 A, alpha = 92.25, beta = 91.37, gamma = 101.48 degrees [ThiM] (Mus musculus) PubMed

 8065.

The authors show that TraB constitutes a novel conjugation system that is clearly distinguished from DNA transfer by a type IV secretion system.[TraB] (Mus musculus) PubMed

 8066.

In Streptomyces coelicolor, both overexpression and deletion of cdgB inhibited aerial-mycelium formation, and overexpression also inhibited production of the antibiotic actinorhodin.[cdgB] (Mus musculus) PubMed

 8067.

crystal belonged to space group P6(3), with unit-cell parameters a = b = 61.265, c = 361.045 A. The asymmetric unit may contain four to six CheW molecules (Mus musculus) PubMed

 8068.

a 2.7 A resolution data set was collected from a single crystal of gp45[ gp45 ] (Mus musculus) PubMed

 8069.

[glycoprotein gp120] While NBD-556 has a stable fluctuation profile, simulations indicate that its presence in the phenylalanine-43 cavity enhances overall mobility of gp120 envelope protein in comparison to CD4, miniprotein bound and uncomplexed forms. (Mus musculus) PubMed

 8070.

HBZ binds with high affinity to the KIX domain of p300/CBP. The two phiXXphiphi motifs in the activation domain of HBZ mediate binding to a single surface of the KIX domain, the mixed-lineage leukemia binding surface. [HBZ protein, HTLV-1] (Mus musculus) PubMed

 8071.

We show that the rat cytomegalovirus CD200 orthologue (e127) binds CD200R on rat peritoneal macrophages. [e127] (Mus musculus) PubMed

 8072.

[HGPRT] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) catalyzes the phosphoribosylation of guanine and hypoxanthine, while Plasmodium falciparum HGPRT acts on xanthine as well. (Mus musculus) PubMed

 8073.

EF2292 (VanV) was found not to be required for vancomycin resistance under the conditions tested, thus coding for another accessory protein in the vanB operon.[VanV] (Mus musculus) PubMed

 8074.

FH5 is a type II formin-like protein encoded by Rice Morphology Determinant (RMD) that functions as an actin-nucleating protein by regulating rice plant morphology by modulating the microtubule- and microfilament-based cytoskeletal systems. (Mus musculus) PubMed

 8075.

The dl2 vascular patterning distortions are strictly associated with a defective polar auxin transport activity and sensitivity to different classes of polar auxin transport inhibitors. [dl2] (Mus musculus) PubMed

 8076.

Data show that OsSDIR1 could complement the drought sensitive phenotype of the sdir1 mutant and overexpressing transgenic Arabidopsis were more sensitive to ABA, indicating that the OsSDIR1 gene is a functional ortholog of SDIR1: [OsSDIR1] (Mus musculus) PubMed

 8077.

Recombinant NT-Als9-2 from C. albicans (residues 18-329) was overexpressed in Escherichia coli, purified and crystallized. Diffraction data were collected to 2.0 A resolution. [NT-Als9-2] (Mus musculus) PubMed

 8078.

here is the 2.0 A resolution structure of a family 32 carbohydrate-binding module of EndoD[endo-beta-1,4-N-acetylglucosamidase] (Mus musculus) PubMed

 8079.

A gene encoding the Bombyx homolog of Drosophila Apterous (BmAp-A) protein is located 4.5 kb downstream of the distal breakpoint of the 1.5-Mb interstitial deletion. (Mus musculus) PubMed

 8080.

HDR(homology-directed DNA repair) was stimulated through individual expression of the viral immediate-early protein IE1-72, mimicking full virus infection. [IE1-72] (Mus musculus) PubMed

 8081.

Diffraction data from two crystal forms of beta-N-acetylhexosaminidase (primitive monoclinic and primitive tetragonal) were collected to resolutions of 3.2 and 2.4 A, respectively[beta-N-acetylhexosaminidase ] (Mus musculus) PubMed

 8082.

AafA has been crystallized at pH 3.4 and diffraction data have been collected to 2.1 A resolution[AafA] (Mus musculus) PubMed

 8083.

Amphioxus connectin has the domain structure of invertebrate connectin-like proteins at its N-terminus and that of vertebrate connectin at its C-terminus. [connectin, Branchiostoma floridae] (Mus musculus) PubMed

 8084.

Rice may have evolved a CPD photolyase that functions in chloroplasts, mitochondria and nuclei, and that contains DNA to protect cells from the harmful effects of UV-B radiation. [CPD photolyase] (Mus musculus) PubMed

 8085.

SasRGA4 is an NBS-LRR protein encoding gene that is necessary for Pia function. SasRGA5, adjacent to SasRGA4, is required for the full function of Pia that specifically recognizes AVR-Pia. [RGA4; RGA5] (Mus musculus) PubMed

 8086.

PDP-1 modulates the expression of several insulin genes that are likely to feed into the IIS pathway to regulate DAF-16 activity. [PDP1] (Mus musculus) PubMed

 8087.

These results suggested that HBZ has dual suppressive effects on IRF-1 function, which may contribute to HTLV-1 related pathogenesis.[HBZ] (Mus musculus) PubMed

 8088.

The results suggest the functional role of SIZ1, a SUMO E3 ligase, in regulating rice anther dehiscence. [Oryza sativa] (Mus musculus) PubMed

 8089.

The cytosolic glutamine synthetase 1;1 has a crucial role in ammonium assimilation and normal shoot growth. [OsGS1;1] (Mus musculus) PubMed

 8090.

BUBR1 is required for ubiquitin-mediated proteasomal degradation of cell division cycle protein 20 in the G0 phase and maintains anaphase-promoting complex/cyclosome-CDC20 homolog 1 activity that regulates level of dishevelled for ciliogenesis [bubr1] (Mus musculus) PubMed

 8091.

(S)-adenosylmethionine (SAM) is one of the two biosynthetic substrates for CqsA. CqsA couples SAM and decanoyl-coenzyme A to produce a previously unknown but potent quorum-sensing molecule, 3-aminotridec-2-en-4-one (Ea-CAI-1). (Mus musculus) PubMed

 8092.

PCRMP3 and 4 play multiple roles during the Plasmodium life cycle; they are essential for the establishment of sporozoite infection in the mosquito salivary gland, and subsequently for development in hepatocytes.[pcrmp3,pcrmp4] (Mus musculus) PubMed

 8093.

Taken together our results suggest a requirement for SNAP-29 in the fusion of post-Golgi vesicles with the recycling endosome for cargo to reach the cell surface. [SNAP 29] (Mus musculus) PubMed

 8094.

PulD protomers normally cross the periplasm together with PulS bound to LolA but when the latter cannot be separated (due to the mutation in lolA), the PulD protomers form dodecamers that insert into the inner membrane.[PulD] (Mus musculus) PubMed

 8095.

in gastric cancer patients infected with cagA-negative H. pylori, the s1m1 allelic combination of vacA was more frequent (54.4%), where s1 was present in 81.8% of the samples [VacA] (Mus musculus) PubMed

 8096.

To maintain normal adhesion and biofilm function in response to exogenous oxidants msrA is upregulated, methionine oxidation of adhesins and perhaps other proteins is reversed, and adhesion and biofilm formation is maintained.[msrA] (Mus musculus) PubMed

 8097.

study identified rainbow trout and Atlantic salmon IL-4/13A, a homologue of mammalian Th2 cytokine genes IL-4 and IL-13; salmonid IL-4/13A and GATA-3 were found highly expressed in thymus, gill, and skin [IL-4/13A] (Mus musculus) PubMed

 8098.

The authors propose that a Msb2, Cek1 and Ace2 signalling pathway addresses PMT genes as downstream targets and that different modes of regulation have evolved for PMT1 and PMT2/PMT4 genes.[Msb2] (Mus musculus) PubMed

 8099.

Amino-acid substitutions in AFLJ of A. oryzae induce inactivation at the protein level, and aflatoxin is not produced. (Mus musculus) PubMed

 8100.

Only hyaluronic acid capsule and M1 protein shared with Sda1 an essentiality for the covRS switching phenotype. [covR,covS] (Mus musculus) PubMed

 8101.

Crystal structure of Sa240: a ribose pyranase (RbsD) homolog with partial active site from Staphylococcus aureus. [Sa240] (Mus musculus) PubMed

 8102.

stunter1 is a novel recessive maternal effect mutation that affects the size and germination efficiency of pollen. [stt1] (Mus musculus) PubMed

 8103.

cloned three ER subtypes (ERalpha, ERbeta1, and ERbeta2), and examined their developmental expression in the gonads of females and males during embryonic and larval development [ERalpha] (Mus musculus) PubMed

 8104.

OVP1 overexpression resulted in enhanced cold tolerance in transgenic rice, which was related to an increased integrity of cell membrane, decreased MDA content and accumulation of proline to higher level as compared with wild type rice seedlings. [OVP1] (Mus musculus) PubMed

 8105.

These results suggest that Ptenb by antagonizing PI3 kinase and its downstream Akt1 and Cdc42 to regulate actin polymerization that is critical for proper cell motility and migration control during gastrulation in zebrafish.[Akt1] (Mus musculus) PubMed

 8106.

The absence of ATX-3 activates the DAF-16 pathway leading to an overexpression of molecular chaperones, which yields knockout animals with an improved capacity for dealing with deleterious stimuli.[Ataxin-3] (Mus musculus) PubMed

 8107.

FhbB crystals diffracted to 1.8 A resolution and belonged to space group P4(3)2(1)2 or P4(1)2(1)2, with unit-cell parameters a = b = 46.76, c = 167.68 A[FhbB] (Mus musculus) PubMed

 8108.

A comparison of the binding mode and thermodynamic stability of the complexes of peptides from the C-terminal domains of HspA and Hpn proteins with four metals (HspA and Hpn). (Mus musculus) PubMed

 8109.

diffraction data were collected to 3.51 A resolution from a crystal of selenomethionine-substituted dihydrouridine synthase in complex with tRNA[dihydrouridine synthase ] (Mus musculus) PubMed

 8110.

The major virulence factor of S. aureus, protein A (SpA) binds directly to osteoblasts.[SpA] (Mus musculus) PubMed

 8111.

Invasion of keratinocytes by S. aureus requires multiple high-affinity FnBRs within FnBPA.[FnBPA] (Mus musculus) PubMed

 8112.

Report the influence of flavonoids on the voltage gating of a single alpha-hemolysin channel in planar lipid membranes. (Mus musculus) PubMed

 8113.

crystal structures of YsxC from Thermotoga maritima and its complex with GDP were determined at maximal resolutions of 2.3 and 1.9 A[YsxC] (Mus musculus) PubMed

 8114.

Cdc48-Npl4-Ufd1 is important for the maintenance of cell wall integrity in order for normal cell growth and division.[Cdc48, Npl4, Ufd1] (Mus musculus) PubMed

 8115.

This study illustrates the importance of multiple intracellular regions of Gap1 in its secretion, transport activity, and down-regulation.[Gap1] (Mus musculus) PubMed

 8116.

The results indicate that the isolated Sic1 kinase-inhibitor domain retains dynamic helical structure and populates collapsed states of different compactness.[Sic1] (Mus musculus) PubMed

 8117.

crystal of the eIF5BDeltaN-eIF1ADeltaN complex diffracted to 3.3 A resolution and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 101.9, b = 120.9, c = 132.8 A[eIF1A and eIF1B] (Mus musculus) PubMed

 8118.

E2-CD81 engagement may contribute to Hepatitis C virus-associated B cell lymphoproliferative disorders and insufficient neutralizing antibody production.[E2] (Mus musculus) PubMed

 8119.

Results suggest that this staphyloccocal nuclease-like protein is the transcription factor that activates the transcription of some pathogenicity-related genes of E. histolytica.[URE1BP] (Mus musculus) PubMed

 8120.

DEP3 is a patatin-like phospholipase A2 that might play a significant role in vascular bundle formation and inflorescence architecture. [DEP3] (Mus musculus) PubMed

 8121.

The crystal 3D-structure of the Candida albicans CA3427 protein at 2.1 A resolution, is reported.[CA3427] (Mus musculus) PubMed

 8122.

Isopeptides bonds were formed between Lys(63)-Asn(214) and Lys(243)-Asn(372) in PitB. [PitB] (Mus musculus) PubMed

 8123.

results indicate that DypB has a significant role in lignin degradation in R. jostii RHA1, is able to oxidize both polymeric lignin and a lignin model compound, and appears to have both Mn(II) and lignin oxidation sites (Mus musculus) PubMed

 8124.

These studies suggest a novel role for PDE5 in erythrocytes.[PDE5] (Mus musculus) PubMed

 8125.

During the purification, three forms of catechol oxidase (39.3, 40.5 and 44.3 kDa) were obtained[catechol oxidase] (Mus musculus) PubMed

 8126.

dTIEG regulates the activity of JAK/STAT pathway suggesting a conserved role of TIEG proteins as positive regulators of TGF-beta signalling.[TIEG] (Mus musculus) PubMed

 8127.

The identification of a novel allele conferring enhanced fosfomycin resistance in a multidrug-resistant pathogen species in a rural river in British Columbia (fosA2). (Mus musculus) PubMed

 8128.

The xa34(t) gene might be a novel recessive resistance gene that confers a new type of plant disease resistance based on our research. [xa34(t)] (Mus musculus) PubMed

 8129.

identified a fibronectin-binding protein, GfbA which functions as an adhesin and invasin [GfbA] (Mus musculus) PubMed

 8130.

The NO associated factor TaNOA might be involved in wheat responses to abiotic stresses. [NOA] (Mus musculus) PubMed

 8131.

A broad characterization of S. agalactiae sortase C1 of the pilus island 2a is presented.[Sortase C1] (Mus musculus) PubMed

 8132.

Transcriptome analyses revealed that Fusarium verticillioides expresses a protein (FvGLLc1) identical to a recently identified cytoplasmic/nuclear GNA-like lectin from maize (ZmGLLc)...not derived from a contaminating Fusarium species. [ZmGLLc] (Mus musculus) PubMed

 8133.

The maturation and assembly of influenza A virus is controlled by the SUMO modification of M1 protein. [M1 protein] (Mus musculus) PubMed

 8134.

Toxoplasma gondii GRA1 stimulates apoptosis of monocytes through autocrine TGF-beta1 signaling. (Mus musculus) PubMed

 8135.

Deletion of atg1 results in impairment of autophagy, in an increased number of peroxisomes, an increase in the enzyme levels of the penicillin biosynthetic pathway, and enhanced production levels of penicillin. (Mus musculus) PubMed

 8136.

ICP27 import does not appear to be regulated by arginine methylation. ICP27 import does not appear to be regulated by arginine methylation. ICP27 nucleus import does not appear to be regulated by arginine methylation. [ICP27] (Mus musculus) PubMed

 8137.

Crystal structures of exo-arabinanase and of its complex with arabinobiose were determined at the high resolutions of 1.14 A to an R(work) of 10.7% (R(free) = 12.8%) and 1.04 A to an R(work) of 10.4% (R(free) = 12.5%). [exo-arabinanase] (Mus musculus) PubMed

 8138.

Dmrt5 is an important player in ventral mesencephalic neural fate specification [Dmrt5] (Mus musculus) PubMed

 8139.

An assay for pathogenicity in the adult rabbit diarrhea model suggested that VopF is involved in eliciting the diarrheal response in infected rabbits.[VopF] (Mus musculus) PubMed

 8140.

role of Zta1p in the yeast adaptation to some stress types and the general functional significance of zeta-crystallins [Zta1p] (Mus musculus) PubMed

 8141.

CLE12 overexpression or the exogenous application of its synthetic peptide inhibits root elongation, indicating that this 12-amino acid CLE12 peptide is biologically active.[CLE12] (Mus musculus) PubMed

 8142.

1.9 A resolution crystal structure of GfcC, a periplasmic protein encoded by the gfc operon, which is essential for assembly of group 4 polysaccharide capsule (Mus musculus) PubMed

 8143.

These results showed that the interaction between herpes simplex virus type 1 ICP27 and human TAP/NXF1 occurred in living cells upon head-to-tail intramolecular association of ICP27.[ICP27] (Mus musculus) PubMed

 8144.

RT-PCR analysis was employed to analyze the differential expression patterns of nitrogen fixation genes under free-living and symbiotic conditions.[nix, fix] (Mus musculus) PubMed

 8145.

Microarray analysis identified global transcriptional differences between glnR+ and glnR mutant strains under varying nitrogen conditions (GlnR). (Mus musculus) PubMed

 8146.

Together, these findings suggest that Asp2 and Asp3 are likely to function in part as chaperones in the early phase of GspB transport.[Asp2, Asp3, GspB] (Mus musculus) PubMed

 8147.

Report the characterization of Thermotoga maritima ferritin reveals an unusual subunit dissociation behavior and efficient DNA protection from iron-mediated oxidative stress. (Mus musculus) PubMed

 8148.

The results link H(2) oxidation via the Hyb enzyme to growth, amino acid transport, and expression of periplasmic proteins that facilitate proton motive force-mediated transport across the outer membrane.[Hyb] (Mus musculus) PubMed

 8149.

Mannosylphosphorylation of N- and O- linked glycans in Yarrowia lipolytica is mediated primarily by a single gene, MPO1 (mannosyl phosphorylation of oligosaccharides 1) without involvement of other genes. [MPO1] (Mus musculus) PubMed

 8150.

Intestinal-enhanced presence of caspase-3+ cells was associated with an increased number of CD3epsilon+ cells located in the lamina propria-submucosa and within the epithelium.[CD3epsilon+] (Mus musculus) PubMed

 8151.

Results suggest a possible role of SMc01113 in interactions mediated by the sRNA-pathway (SMc01113). (Mus musculus) PubMed

 8152.

Hsl1 deletion mutants displayed an inability to synthesize/accumulate glycerol as a compatible solute. [Hsl1] (Mus musculus) PubMed

 8153.

AMBER force field parameters were employed for the molecular dynamics simulation of rabbit 15S-lipoxygenase in aqueous solutions. [15S-lipoxygenase ] (Mus musculus) PubMed

 8154.

The addition of the metabolite analogs of glycine betaine enhanced not only the rate constant but also the thermostability, salt tolerance, and substrate specificity of alpha-glucosidase. [alpha-glucosidase] (Mus musculus) PubMed

 8155.

Substrate specificity of cdk1 gradually changes throughout the cell cycle. (Mus musculus) PubMed

 8156.

Ubp6 facilitates proteosomal assembly. (Mus musculus) PubMed

 8157.

CoPK32 is a novel stress-responsive protein kinase in the mushroom Coprinopsis cinerea (Mus musculus) PubMed

 8158.

RpoE1, an extracytoplasmic function sigma factor, is a repressor of the flagellar system. [RpoE1] (Mus musculus) PubMed

 8159.

VarS/VarA two-component system controls the expression of virulence proteins through ToxT regulation. [VarS, VarA] (Mus musculus) PubMed

 8160.

FlgD contributes to efficient flagellum hook polymerization. [FlgD] (Mus musculus) PubMed

 8161.

Either Pep or GprA was shown to be necessary for fungal growth in protein medium at low pH. [Pep, GprA] (Mus musculus) PubMed

 8162.

Pectin methylesterase (EC 3.1.1.11), a cell-wall remodeling enzyme, was activated in response to heat shock, and its elevated activity was related to the recovery of the HS-released Ca(2+) concentration.[PME] (Mus musculus) PubMed

 8163.

The TolC enhancement of extreme-acid survival includes Gad induction, but TolC-dependent growth rates below pH 6.5 do not involve Gad.[GadA, GadB] (Mus musculus) PubMed

 8164.

The ubiquitin-conjugating enzyme UbcX causes the ubiquitylation of XErp1, followed by its dissociation from the anaphase-promoting complex/cyclosome. [UbcX - Xenopus Ubch10 orthologue] (Mus musculus) PubMed

 8165.

Both UDPDH and mshA gene expression are required for successful colonization of Euprymna tasmanica. [UDPDH] (Mus musculus) PubMed

 8166.

The internalization of SLO-negative Streptococcus pyogenes was blocked by knocking down of the expression of clathrin or dynamin. [SLO] (Mus musculus) PubMed

 8167.

These results indicate that TaNF-YB3 is involved in the positive regulation of a number of photosynthesis genes in wheat. [TaNF-YB3] (Mus musculus) PubMed

 8168.

OsBBI1 modulates broad-spectrum resistance to blast fungus by modifying cell wall defence responses.[OsBBI1] (Mus musculus) PubMed

 8169.

Cdc55 (PP2A) regulation of Net1 is essential for preventing early exit from meiosis I. (Mus musculus) PubMed

 8170.

we provide in vitro evidence that a complex of the yeast protein disulfide isomerase Pdi1p and the mannosidase Htm1p processes Man(8)GlcNAc(2) carbohydrates bound to unfolded proteins, yielding Man(7)GlcNAc(2) [Pdi1 & Htm1] (Mus musculus) PubMed

 8171.

Pho4 binding is not sufficient for transcriptional activation-a cooperative interaction between Pho2 and Pho4 specifies genes that are activated [Pho4] (Mus musculus) PubMed

 8172.

[HTLV-1 envelope glycoprotein gp46] gp46 surface glycoprotein is recognized by neutralizing antibodies and cytotoxic T cells following a protective immune response, therefore it represents an attractive component for an HTLV-1 vaccine. (Mus musculus) PubMed

 8173.

CWA1/BC1 plays a role in assembling secondary cell wall materials at appropriate sites, enabling synthesis of highly ordered secondary cell wall structure with solid and flexible internodes in rice.[CWA1] (Mus musculus) PubMed

 8174.

The p25 subunit of dynactin is critical for dynein-mediated early endosome movement. [An5022/p25] (Mus musculus) PubMed

 8175.

To reveal how Mot1 specifically disrupts TBP-DNA complexes, we combined crystal and electron microscopy structures of Mot1-TBP from Encephalitozoon cuniculi with biochemical studies. [Mot1 & TBP] (Mus musculus) PubMed

 8176.

(chitinases ChiA and ChiB) The transglycosylation properties of family 18 chitinases ChiA and ChiB may be manipulated by mutations that affect the configuration of the catalytic machinery and the affinity for sugar acceptors. (Mus musculus) PubMed

 8177.

a specific signal recognition particle-dependent substrate, Sec71p, is targeted exclusively to Ssh1p [Ssh1p] (Mus musculus) PubMed

 8178.

data imply a new mechanism, actin-mediated sorting, in which WASH and the Arp2/3 complex polymerize actin on vesicles to drive the separation and recycling of proteins such as the V-ATPase [WASH] (Mus musculus) PubMed

 8179.

these data suggest that OsJAR1 and OsJAR2 jasmonyl-L-isoleucine synthases are differentially involved in the activation of JA signalling in response to wounding and pathogen challenge in rice. [OsJAR1] [OsJAR2 ] (Mus musculus) PubMed

 8180.

VasX localizes to the bacterial membrane and interacts with membrane lipids. We present VasX as a novel virulence factor of the T6SS. (Mus musculus) PubMed

 8181.

The role of Cdc5 in the recombination checkpoint was analysed.[Cdc5] (Mus musculus) PubMed

 8182.

propose VacA augments H pylori-induced mucosal inflammation in the stomach by causing programmed necrosis of gastric epithelial cells and release of proinflammatory proteins and may contribute to pathogenesis of gastric cancer and peptic ulceration [VacA] (Mus musculus) PubMed

 8183.

The study identifies ATP-hydrolysis induced conformational changes in a complete ABC exporter (Sav1866) from Staphylococcus aureaus, using molecular dynamics (MD) simulations. [ABC exporter] (Mus musculus) PubMed

 8184.

The study reports the crystal structure of An. gambiae serpin 2, the first serpin fold from a dipteran insect, in its native conformation to 1.75-A resolution. [serpin 2] (Mus musculus) PubMed

 8185.

The analyses indicate that neither the semiopen nor an open conformation with native bottom-to-top flap ordering can effectively bind the substrate and reach to a closed conformation for hydrolysis. [HIV-1 protease] (Mus musculus) PubMed

 8186.

ORF124L attenuates nuclear factor-kappaB activation and interacts with IkappaB kinase beta. [ORF124L] (Mus musculus) PubMed

 8187.

These results are consistent with the interpretation that Npc1p is important for normal transport of ergosterol from the vacuole and is essential for proper membrane function under particular environmental conditions.[Npc1] (Mus musculus) PubMed

 8188.

overexpression resulted in the generation of singlet oxygen and other reactive oxygen species and produced a chlorophyll-dependent regional cell death phenotype on leaves of rice seedlings [SGR] (Mus musculus) PubMed

 8189.

delineated the erythrocyte binding domain (EBD) of one member of the reticulocyte binding protein homologue family, termed Py235 [Py235] (Mus musculus) PubMed

 8190.

NS80 interacts with proteins NS38, VP4, and VP6. [NS80] (Mus musculus) PubMed

 8191.

The X-ray structure of the anaerobic enzyme-substrate complex gives credit to substrate activation before the dioxygen fixation in the peroxo hole, where incoming and outgoing reagents (dioxygen, water, hydrogen peroxide) are handled. [urate oxidase] (Mus musculus) PubMed

 8192.

Functioning of the fur Gene is Required for the acid tolerance response. [Fur] (Mus musculus) PubMed

 8193.

The cag4 of Helicobacter pylori NCTC11637 has the enzyme activity of lytic transglycosylase. [cag4] (Mus musculus) PubMed

 8194.

The crystal structure of Staphylococcus aureus MenH has been determined at 2 A resolution.[MenH] (Mus musculus) PubMed

 8195.

a novel role for RedJ in facilitating transfer of a dodecanoyl chain from one acyl carrier protein to another en route to the key biosynthetic intermediate 2-undecylpyrrole [RedJ] (Mus musculus) PubMed

 8196.

in vitro interaction of Pkh1 and Sch9 [PKH1][Pkh2][Pkh3][Sch9] (Mus musculus) PubMed

 8197.

Three phosphorylation sites in Tub4 were found to be critical for Tub4 stability and microtubule organization.[Tub4] (Mus musculus) PubMed

 8198.

The present results demonstrate that NS1 protein of Influenza A Virus interacts with heat hock protein Hsp90 and meidates the apoptosis induced by influenza A virus through the caspase cascade. (Mus musculus) PubMed

 8199.

NS4A is identified as a critical determinant of flavivirus replication [NS4A] (Mus musculus) PubMed

 8200.

Fur.Mn(2+), by binding to the upstream BoxA sequence, directly stimulates the expression of hilD in S. enterica.[fur, hilD] (Mus musculus) PubMed

 8201.

NS4A is identified as a critical determinant of flavivirus replication [NS4A] (Mus musculus) PubMed

 8202.

crystals of SM23 belonged to the I-centred tetragonal space group I4(1)22, with unit-cell parameters a = b = 126.6, c = 190.9 A[Sm23] (Mus musculus) PubMed

 8203.

OsiICK1 and OsiICK6 interacted with OsCYCD, but differed in their interactions with CDKA. [OsiICK1, OsiICK6] (Mus musculus) PubMed

 8204.

Hypoxia enhances mesenchymal stem cells to differentiate into osteogenic lineage cells and suggest that Cbfalpha1 may be negatively regulated by HIF-1alpha.[Cbfalpha1] (Mus musculus) PubMed

 8205.

data implicate the Ebp pili as having some role in collagen adherence, albeit less than that of Ace, and a very major role in fibrinogen adherence[ebpA, ebpB, ebpC] (Mus musculus) PubMed

 8206.

Two-component system RgfA/C activates the fbsB gene encoding major fibrinogen-binding protein in highly virulent CC17 clone group B Streptococcus.[RgfA/C protein, S.agalactiae; fbsB protein, S.agalactiae] (Mus musculus) PubMed

 8207.

Ebp pili, are highly conserved and mediate adherence to platelets, suggesting that Ebp pili may be a reasonable immunotherapeutic target for prevention or possibly treatment of endocarditis caused by this species. [ebp] (Mus musculus) PubMed

 8208.

evidence that in exponentially growing Salmonella enterica serotype Enteritidis, Dps is vital for protection against common killing mechanism of bactericidal antibiotics, a mechanism manifested by hydroxyl radical production via Fenton reaction [Dps] (Mus musculus) PubMed

 8209.

The results reveal that NumA1 is a true nucleolar protein and the only nucleolar calmodulin-binding protein identified in Dictyostelium. The possible use of nuclear/nucleolar localization signal-mediated drug targeting to nucleoli is discussed. (NumA1) (Mus musculus) PubMed

 8210.

Cohesin inactivation alters the expression of positionally clustered genes. (Mus musculus) PubMed

 8211.

The investigators used the Streptococcus suis Dps-like peroxide resistance protein (SsDpr) to study the properties of the iron core in the wild-type protein and in four mutants (E64A, E67A, E68A, and E75A). [Dps-like peroxide resistance protein] (Mus musculus) PubMed

 8212.

The study dissected the nucleotide cycle of the isolated helicase-like domain of T. maritima reverse gyrase, the influence of DNA on the nucleotide cycle, as well as coupling between DNA and nucleotide binding. [reverse gyrase] (Mus musculus) PubMed

 8213.

A genome-wide transcriptional analysis identified genes upregulated in response to GTS1 induction, most of which were found to be regulated by the Tup1-Cyc8 co-repressor. [GTS1][Tup1][Cyc8] (Mus musculus) PubMed

 8214.

Data suggest that eukaryotes with regional centromeres make use of different strategies for maintenance of CenH3 at centromeres, and we suggest a model in which centromere proteins nucleate at the core but require DIM-5 and HP1 for spreading. (Mus musculus) PubMed

 8215.

results suggest that Hbx4 modulates DdCAD-1-mediated cytokinesis and cell-type proportioning [DdCAD-1] (Mus musculus) PubMed

 8216.

gliG was found not to be involved in fungal self-protection against gliotoxin [gliG] (Mus musculus) PubMed

 8217.

Complementation of the rice expansin 17(OsEXPA17) mutant with other root hair Expansins (OsEXPA30 and Arabidopsis EXPA7) can restore root hair elongation, indicating functional conservation of these root hair EXPAs in monocots and dicots. [EXPA17] (Mus musculus) PubMed

 8218.

Polymorphisms of the Cytochome b gene show that there are distinct genotypes within Colombian Trypanosoma cruzi I populations. [Cytb] (Mus musculus) PubMed

 8219.

There was a noticeable length polymorphism in PvMCA1 of P. vivax isolates, linked to the presence of tandem repeat units in the intronic region of the gene. [metacaspase 1] (Mus musculus) PubMed

 8220.

PpPRR2 serves as a clock component in P. patens [PRR2] (Mus musculus) PubMed

 8221.

purified and characterized a heterologously expressed gene product of AO090103000153 [OcpC] (Mus musculus) PubMed

 8222.

AipA colocalized with Abp1 at the tip region, suggesting that AipA functions in endocytosis. [AipA] (Mus musculus) PubMed

 8223.

Identification and expression of soul/p22HBP genes in zebrafish (Mus musculus) PubMed

 8224.

hnRNP K is the nexus of a novel post-transcriptional regulatory module controlling the synthesis of proteins that integrate all three cytoskeletal polymers to form the axon. (Mus musculus) PubMed

 8225.

Local accumulation or high levels of expression of EndoS in certain Streptococcus pyogenes strains may contribute to virulence.[EndoS] (Mus musculus) PubMed

 8226.

A phiSM101 muramidase gene (psm) revealed by this study can be assumed to encode an N-acetylmuramidase, since the N-terminal catalytic domain deduced from the gene shows high homology of those of N-acetylmuramidases.[psm] (Mus musculus) PubMed

 8227.

Plzf was found to be localized in the nucleus of both type A and type B spermatogonia until the 8-cell clone. (Mus musculus) PubMed

 8228.

Trigger factor plays an important part in the pathogenesis and stress tolerance of S. suis serotype 2 infection. [tig] (Mus musculus) PubMed

 8229.

Psy-A1 alleles control flour yellowness in Australian hexaploid wheat genotypes. [phytoene synthase 1] (Mus musculus) PubMed

 8230.

Rsn1 is a cytokinin-O-glucosyltransferase that controls sensitivity of rice to a necrosis-inducing phytotoxin from Rhizoctonia solani. [Rsn1] (Mus musculus) PubMed

 8231.

The ds1 gene encodes Leucine-Rich Repeat Receptor Kinases (LRR-RKs) and is involved in the resistance/susceptibility to target leaf spot. [ds1] (Mus musculus) PubMed

 8232.

In this study, the ncgl1108 (named as pheP (Cg)) was identified as a new L-Phe specific transporter from Corynebacterium glutamicum RES167.[pheP] (Mus musculus) PubMed

 8233.

Determined is the crystal structure of Leishmania major MIX to a resolution of 2.4 A. MIX forms an all alpha-helical fold comprising seven alpha-helices that fold into a single domain. [MIX] (Mus musculus) PubMed

 8234.

A stem rust resistance gene was mapped to the long arm 6V#3L in T6AS.6V#3L and was designated as Sr52. [Sr52]. (Mus musculus) PubMed

 8235.

These data indicate that PAF enhances conidiation in Penicillium chrysogenum by modulating the expression of brlA, the central regulatory gene for mitospore development.[PAF] (Mus musculus) PubMed

 8236.

[2 genes]The structure of Lsp1 and Pil1 consists mainly of a banana-shaped BAR domain. (Mus musculus) PubMed

 8237.

interference with mouse ATF6beta-dependent immune responses is a novel pathogenic mechanism induced by Toxoplasma gondii virulence factor ROP18 (Mus musculus) PubMed

 8238.

Dysfunction of homogentisate oxygenase (VC1345) causes homogentisate accumulation and pigment formation in naturally pigmented strains of Vibrio cholerae.[homogentisate oxygenase] (Mus musculus) PubMed

 8239.

These results suggest that the O-acetylesterase is probabbly essential for the synthesis of capsular Neu5Ac in S. suis. [NeuA] (Mus musculus) PubMed

 8240.

the structural basis for the functional cooperation of a helicase domain with a DNA topoisomerase in reverse gyrase [reverse gyrase] (Mus musculus) PubMed

 8241.

the histone deacetylase Sir2 plays a role in chromosomal position effects across the chromosome.[Sir2] (Mus musculus) PubMed

 8242.

Both heads of one kinesin dimer are microtubule-bound at submicromolar ATP concentrations.[Kinesin] (Mus musculus) PubMed

 8243.

Most importantly, when the point mutation converting Arg 19 to Leu in V1 was introduced into the full-length tomato yellow leaf curl virus-Israel genome, it disrupted its ability to cause symptoms.[V1] (Mus musculus) PubMed

 8244.

These data support the functional characterization of SO2426 as a positive regulator of siderophore-mediated iron acquisition.[SO2426] (Mus musculus) PubMed

 8245.

This report demonstrates the significant role Ohr and OhrR proteins play in bacterial stress resistance against organic peroxides in Sinorhizobium meliloti.[Ohr and OhrR] (Mus musculus) PubMed

 8246.

A steady-state analysis shows that high light repression can indeed occur at intermediate oxygen levels if PpsR is reduced on a faster timescale than AppA and if the electron transfer from AppA to PpsR is effectively irreversible.[PssR, AppA] (Mus musculus) PubMed

 8247.

The results indicate that both Nax genes have the potential to improve the salt tolerance of bread wheat.[Nax1, Nax2] (Mus musculus) PubMed

 8248.

DdCAD-1 influences the sorting behavior of cells in slugs by its differential distribution on the prestalk and prespore cells.[DdCAD-1] (Mus musculus) PubMed

 8249.

data indicate a conservation of the biochemical mechanisms of proliferating cellular nuclear antigen-mediated interactions between metazoa, yeast and parasitic protozoa [proliferating cellular nuclear antigen ] (Mus musculus) PubMed

 8250.

distinct structural and antigenic properties of kappa-5 glycans suggest a specific role for kappa-5 in schistosome egg immunogenicity. [kappa-5] (Mus musculus) PubMed

 8251.

Cys-520 and Cys-574 are not likely to be involved in the catalytic mechanism of thioredoxin glutathione reductase [thioredoxin glutathione reductase] (Mus musculus) PubMed

 8252.

The glutamate-139 residue of V-ATPase NtpK subunit is indispensable for its enzymatic activity that is linked with the salt tolerance. [NtpK] (Mus musculus) PubMed

 8253.

HmrA is a peptidase that participates in resistance mechanisms in vivo in the presence of beta-lactams (Mus musculus) PubMed

 8254.

integrase-induced intramolecular conformational change in the viral DNA ends [integrase] (Mus musculus) PubMed

 8255.

The formation of the rice prolamin-containing protein body I is initiated by the accumulation of CysR10. [CysR10] (Mus musculus) PubMed

 8256.

These experiments showed that the NH2-terminal of the classical swine fever virus NS2 protein was highly hydrophobic and the protein localized in the endoplasmic reticulum. (Mus musculus) PubMed

 8257.

The products of both easC (catalase) and easE (FAD-dependent oxidoreductase) are required for conversion of N-methyl-4-dimethylallyltryptophan (N-Me-DMAT) to chanoclavine-I. (Mus musculus) PubMed

 8258.

By replacing rat cardiac troponin I (cTnI) in a mammalian cTn complex with trout cTnI it was demonstrated that this protein increases the Ca2+ affinity and reduces the influence of PKA phosphorylation on the Ca2+ affinity of the cTn complex.[PKA] (Mus musculus) PubMed

 8259.

PKA treatment phosphorylated myosin light chain 2 but not cTnI or cardiac myosin binding protein C. Function of trout cardiac contractile element is altered by PKA phosphorylation in a manner different from that in mammalian heart.[PKA] (Mus musculus) PubMed

 8260.

Ixr1, but not Dun1, is required for the proper RNR1 expression both during an unperturbed cell cycle and after DNA damage [Ixr1 and Rur1][strain not found] (Mus musculus) PubMed

 8261.

that Est3 acts downstream of both Est2 and Est1 and that the putative activation function of Est1 can be explained by its role in recruiting Est3 to telomeres [Est3, and Est1] [strain not found] (Mus musculus) PubMed

 8262.

This paper tested the hypothesis that overexpression (OX) of GS1 in rice improves utilization N use efficiency.[Glutamine synthetase 1] (Mus musculus) PubMed

 8263.

interaction between Rtt107 and the SMC5/6 [Rtt107][SMC5][SMC6] (Mus musculus) PubMed

 8264.

The specific activity of the SCR II E228S variant was increased approximately 7-20 times for acetophenones. [SCR II] (Mus musculus) PubMed

 8265.

SCR and RCR mainly distributed in the intracellular membrane and cytoplasm. [SCR and RCR] (Mus musculus) PubMed

 8266.

crystal structure of the 30 K protein from the silkworm Bombyx mori reveals a new member of the beta-trefoil superfamily. [Bmlp7] (Mus musculus) PubMed

 8267.

Reduced HSP82 expression markedly attenuates the virulence of Histoplasma yeast in vivo.[Hsp82] (Mus musculus) PubMed

 8268.

Taken together, these data reveal that the targeting of NSvc4 to plasmodesmata exploits the early secretory pathway and the actin-myosin VIII motility system in the leaves of a non-host plant, Nicotiana benthamiana.[NSvc4] (Mus musculus) PubMed

 8269.

Shigella flexneri type III secreted effector OspF inhibits c-Jun expression at the transcriptional level. [OspF] (Mus musculus) PubMed

 8270.

Together, these results consistently demonstrate that MtrC and OmcA are the terminal reductases used by Shewanella oneidensis MR-1 for extracellular Cr(VI) reduction where OmcA is a predominant Cr(VI) reductase.[MtrC] (Mus musculus) PubMed

 8271.

crystal structure of free and inhibitor bound plasmepsin I (Mus musculus) PubMed

 8272.

These data show that the ShvR-regulated genes BCAS0208 to BCAS0201 are required for the rough colony morphotype, biofilm and pellicle formation, and virulence in Burkholderia cenocepacia.[ShvR] (Mus musculus) PubMed

 8273.

biophysical properties of the NS1A ED from H3N2 influenza A/Udorn/307/1972 (Ud) virus in solution [NS1A] (Mus musculus) PubMed

 8274.

The authors conclude that both AlpA and AlpB contribute to Helicobacter pylori laminin binding.[AlpA and AlpB] (Mus musculus) PubMed

 8275.

The authors conclude that type 1 pilus expression in pneumococcus exhibits a bistable phenotype, which is dependent upon the molecular interplay between the RlrA and RrgA proteins.[ RlrA and RrgA] (Mus musculus) PubMed

 8276.

Intranasal exposure to staphylococcal enterotoxin B in C57BL/6 wild-type mice caused acute lung injury characterized by vascular leak, cytokine storm, and infiltration of mononuclear cells in the lungs. [staphylococcal enterotoxin B] (Mus musculus) PubMed

 8277.

These findings suggest that PfRH2a and, most likely, the other members of the RH family, depending on their processing stage, can engage different receptors at different stages of the invasion process.[RH2a] (Mus musculus) PubMed

 8278.

The structural details and their comparison give new insights into substrate and activator binding to adenosine kinase at the molecular level.[adenosine kinase] (Mus musculus) PubMed

 8279.

NCp7 binding and functional remodeling of the human anticodon stem and loop domain (hASL(Lys3)) were studied.[NCp7] (Mus musculus) PubMed

 8280.

The conformation of a 27-residue Nt-CCR5 peptide, sulfated at Y10 and Y14, was studied both in its free form and in a ternary complex with deglycosylated gp120 and a CD4-mimic peptide.[gp120] (Mus musculus) PubMed

 8281.

The inhibition of IN-DNA interaction by the LEDGF/p75 C-terminus may provide a novel strategy for the inhibition of HIV IN activity.[Integrase] (Mus musculus) PubMed

 8282.

(211)KELQKQITK and (262)RRKAK regions of IN C-terminal domain are required for Impalpha3 interaction and HIV-1 cDNA nuclear import.[Integrase] (Mus musculus) PubMed

 8283.

The expressed hepatitis E virus ORF1 gene product does not undergo proteolytic processing, indicating that the replicase precursor of HEV is potentially unique in this regard. (Mus musculus) PubMed

 8284.

The results suggest that site I of HA33 is quite unique in that it mainly recognizes Neu5AcN-acetylneuraminic acid, and site II seems less important for the lectin specificity. [HA33] (Mus musculus) PubMed

 8285.

A transgenic P. berghei, in which endogenous Pbdhfr allele was replaced with the mutant PfdhfrS108N, was generated and confirmed to have normal growth rate comparing to parental non-transgenic parasite and also confer resistance to pyrimethamine. [PfDHFR] (Mus musculus) PubMed

 8286.

crystal structures of Burkholderia cenocepacia dihydropteroate synthase [dihydropteroate synthase] (Mus musculus) PubMed

 8287.

distinct histone H3 pairs of variants arose independently in each of these clades and in basidiomycetes [histone H3] (Mus musculus) PubMed

 8288.

Hd1 and Ehd1 together control the number of primary branches in the panicle. [Ehd1] (Mus musculus) PubMed

 8289.

Atg35 is a new Atg protein that relocates to the peri-nuclear structure and specifically regulates micropexophagic apparatus formation during micropexophagy (Mus musculus) PubMed

 8290.

The functional characterization of a multidrug and toxin extrusion transporter (MATE2), from Medicago truncatula, is reported.[MATE2] (Mus musculus) PubMed

 8291.

[nef] A rhesus macaque CD8-positive T cell line recognizes N-myristoylated peptides of simian immunodeficiency virus (SIV) nef; Nef peptide-specific T cells expand significantly in monkeys with simian immunodeficient virus (SIV) infection. (Mus musculus) PubMed

 8292.

The analysis constitutes the first characterization of an Oligosaccharyltransferase from delta-proteobacteria involved in N-linked protein glycosylation. (Mus musculus) PubMed

 8293.

activation of digestion by ILPs may also underlie the growth promoting effects of insulin and TOR signaling in other species [ILP3][TOR] (Mus musculus) PubMed

 8294.

The high affinity and specificity of the S. cerevisiae Cdc13 DNA binding domain for single-stranded telomeric DNA are not widely shared by other fungal Cdc13 proteins.[Cdc13] (Mus musculus) PubMed

 8295.

The N-terminal of influenza A virus PB1 mediates its binding to host RanBP5. (Mus musculus) PubMed

 8296.

Fbp1 is essential for fungal sporulation and virulence in C. neoformans, which likely represents a conserved novel virulence control mechanism. [Fbp1] (Mus musculus) PubMed

 8297.

Alanine substitutions within a linker region of the NS1 alter its subcellular localization and attenuate virus replication. [NS1] (Mus musculus) PubMed

 8298.

the importance of Tyr13, Glu77 and Ala117 specific to plasmepsin V that facilitates the accommodation of arginine at P in the RxLxE/Q/D motif [plasmepsin V] (Mus musculus) PubMed

 8299.

The lipid modifications on ornithine-containing lipids due to OlsD occur on the amide-linked fatty acyl chain.[OlsD] (Mus musculus) PubMed

 8300.

Purification and biochemical characterization of a novel glutamyl endopeptidase (VSPase)secreted by a clinical isolate of Staphylococcus aureus. [VSPase] (Mus musculus) PubMed

 8301.

Os API5 is a nuclear protein that interacts with two DEAD-box ATP-dependent RNA helicases, API5-INTERACTING PROTEIN1 (AIP1) and AIP2.[AIP1, AIP2] (Mus musculus) PubMed

 8302.

Downregulation of BNR2 causes defects in sporangium formation and a decrease in the total spore number.[BNR2] (Mus musculus) PubMed

 8303.

Ubp15's enzymatic activity is regulated by the N- and C-terminal domains that flank the catalytic core domain.[Ubp15] (Mus musculus) PubMed

 8304.

NLS1 encodes a CC-NB-LRR protein that mediates both salicylic acid and NPR1-independent defense signaling pathways in rice. [NLS1] (Mus musculus) PubMed

 8305.

The quorum sensing response is mediated by base pairing between Qrr sRNAs and hapR mRNA and Hfq stabilizes Qrr/hapR complex formation. [Hfq] (Mus musculus) PubMed

 8306.

The present study identified and characterized, for the first time in an oenological Saccharomyces cerevisiae strain, a gene involved in foam formation, named FPG1 (foam-promoting gene).[FPG1] (Mus musculus) PubMed

 8307.

Mid1, a mechanosensitive calcium ion channel, affects growth, development, and ascospore discharge in the filamentous fungus Gibberella zeae. [Mid1] (Mus musculus) PubMed

 8308.

mutations of Tyr8, Gln50, and Met93 disrupt the ability of PixD dimers to interact with PixE to form a higher-order PixD(10)-PixE(5) complex.[pixE, PixD] (Mus musculus) PubMed

 8309.

a mutant rice lesion initiation 1 (rlin1) encoding a putative coproporphyrinogen III oxidase in tetrapyrrole biosynthesis pathway [RLIN1] (Mus musculus) PubMed

 8310.

show that Hfq cannot stably bridge the RNAs. Persistent ternary complexes only form when the two RNAs are complementary[Hfq] (Mus musculus) PubMed

 8311.

Cdc31 displays one Ca(2+)/Mg(2+) mixed site in the N-terminal domain and two low-affinity Ca(2+) sites in the C-terminal domain.[Cdc31] (Mus musculus) PubMed

 8312.

the Ceramide glucosyltransferase gene is indispensable in the germline and that an ample supply of GlcCer is needed for oocytes and fertilized eggs to maintain normal membranes and to proceed through the normal cell cycle. (Ceramide glucosyltransferase ) (Mus musculus) PubMed

 8313.

Disruption of FIT2 genes reduced accumulation of triacylglycerols and reduced the formation of lipid droplets. [FIT2] (Mus musculus) PubMed

 8314.

Transgenic lines with RNAi-suppressed SSIIa and SSIIIa exhibited changed grain development, and reduced short and long amylopectin chain contents. [SSIIa; SSIIIa] (Mus musculus) PubMed

 8315.

The differences found in the phosphorylation status of Rab21 are related to water stress tolerance in Oryza sativa. (Mus musculus) PubMed

 8316.

The mei4Delta mutant was found to arrest cell division with its telomeres clustered at the spindle pole body, demonstrating a role for Mei4 in telomere dispersion.[mei4] (Mus musculus) PubMed

 8317.

Cir1 contributes to copper mediated enhancement of sexual filamentation. Cir1 influences the expression of mating. [Cir1] pheromone genes suggesting that this protein plays a role in the early phase of sexual development on V8 mating medium. (Mus musculus) PubMed

 8318.

KLF6a and KLF7a as important mediators of optic nerve regeneration and suggest that not all induced genes are essential to mount a regenerative response (Mus musculus) PubMed

 8319.

the same E3 ubiquitin ligase known to regulate Snail family proteins, Partner of paired (Ppa), also controlled Twist stability and did so in a manner dependent on the Twist WR-rich domain [ppa] (Mus musculus) PubMed

 8320.

Differences in the relative contributions of cardiolipin synthase 1 (CLS1) and CLS2 to cardiolipin accumulation under different triggering conditions suggest differences in the role and regulation of these two enzymes.[CLS1; CLS2] (Mus musculus) PubMed

 8321.

The alpha-synuclein motifs target distinct vesicles in cells by direct interaction with different lipid environments. (Mus musculus) PubMed

 8322.

Aar2p acts as a phosphorylation-controlled U5 snRNP assembly factor that regulates the incorporation of the particle-specific Brr2p [Aar2, strains not in gene] (Mus musculus) PubMed

 8323.

SBEIIa is necessary in producing an amylopectin structure amenable to degradation by starch metabolism enzymes.[Sbe2a] (Mus musculus) PubMed

 8324.

identify catalytically important residues and show that the enzyme reaction proceeded through the two-step mechanism involving the formation of a covalent intermediate.[epoxide hydrolase ] (Mus musculus) PubMed

 8325.

This study revealed a complex interdependency of Ca(2+) and phosphoinositide-specific phospholipase C activity, with phosphoinositide-specific phospholipase C being essential throughout gamete formation.[phosphoinositide-specific phospholipase C] (Mus musculus) PubMed

 8326.

The five nucleotides identified are the target DNA-binding sequence of ART1.[ART1] (Mus musculus) PubMed

 8327.

The recombinant protein based on gp82, the Trypanosoma cruzi metacyclic trypomastigote surface molecule that mediates cell adhesion/invasion, induced exocytosis in HeLa cells. (Mus musculus) PubMed

 8328.

These data suggest that actin bundling may improve the ability of the myosin motor system for nanotransport applications.[Myosin II] (Mus musculus) PubMed

 8329.

Comparative sequence analysis identified interspecies variable- and conserved-parts in pvs230, and provides evidence that Pvs230, particularly CRDs, has limited polymorphism. [Pvs230] (Mus musculus) PubMed

 8330.

Using zebrafish we determined that zfhx1b was expressed in the developing liver during biliary growth and remodeling, and that morpholino antisense oligonucleotide-mediated knockdown of zfhx1b led to defects in biliary development. (Mus musculus) PubMed

 8331.

Brown planthopper feeding rapidly initiated the ethylene signaling pathway and up-regulated Bphi008a transcript levels after 6 to 96 h of feeding.[Bphi008a] (Mus musculus) PubMed

 8332.

H-NS have a higher relative binding affinity for the ctx promoter than for the tcpA promoter. [CTX, H-NS] (Mus musculus) PubMed

 8333.

rice FT homologue Hd3a interacts with 14-3-3 proteins in the apical cells of shoots, yielding a complex that translocates to the nucleus and binds to the Oryza sativa (Os)FD1 transcription factor, a rice homologue of Arabidopsis thaliana FD [Hd3a] (Mus musculus) PubMed

 8334.

glyceraldehyde-3-phosphate dehydrogenase 2 interacts with glutathione peroxidase 3 through its carboxyl-terminal domain both in vitro and in vivo [GAPDH2] (Mus musculus) PubMed

 8335.

The results do not support the role of MEF2A as direct regulators of primary muscle fiber type differences. (Mus musculus) PubMed

 8336.

The scratch2 protects neurons from apoptosis by maintaining Puma levels low during normal embryonic development.(Scratch2 protein) (Mus musculus) PubMed

 8337.

The bioactive peptide, BSP-I, from chicken humoral immune system, might provide novel insights on linking between humoral immune system and development of effective immunotherapeutic strategies for treating human cancers diseases. (Mus musculus) PubMed

 8338.

Transpirational demand triggers a dramatic increase in gene expression of OsPIP2;5. [OsPIP2;5] (Mus musculus) PubMed

 8339.

Disrupting the IPT1 gene greatly reduced Candida adhesion to gingival epithelial cells, compared to the wild-type and revertant strains.[IPT1] (Mus musculus) PubMed

 8340.

These results indicated that CIA6 is required for the formation of the pyrenoid and further supported the notion that the pyrenoid is required for a functional CO(2)-concentrating mechanism in C. reinhardtii.[CIA6] (Mus musculus) PubMed

 8341.

Two functional domains of VvpS is essential for autolysis. [VvpS] (Mus musculus) PubMed

 8342.

SpkG play essential roles in Synechocystis sp. for sensing the high salt signal directly.[SpkG] (Mus musculus) PubMed

 8343.

Data indicate that ChpH is required for promoting aerial development: [ChpH] (Mus musculus) PubMed

 8344.

previously undescribed roles for the Spt16 M-domain and extreme carboxy terminus in regulating interactions between Spt16 and chromatin during the process of transcription elongation [Spt16] (Mus musculus) PubMed

 8345.

Bxi1p, like its metazoan homologs, is an ER-localized protein that links the unfolded protein response and programmed cell death [Bxi1p] (Mus musculus) PubMed

 8346.

These results demonstrated the molecular adaptation of parasite NDKbs in order to exert their biological functions intra-parasite and when secreted by regulating ATP levels of host cells.[NDKb] (Mus musculus) PubMed

 8347.

HCV NS3 protein is involved in the activation of the Notch-signaling pathway through the targeting to both SRCAP and p400 (Mus musculus) PubMed

 8348.

Expression of PVX TGBp3 from a heterologous vector induces the same set of genes in N. benthamiana and Arabidopsis (Arabidopsis thaliana) leaves.[TGBp3] (Mus musculus) PubMed

 8349.

FlgM and FliA controls flagellum number and is essential for efficient swimming and biofilm formation. [FlgM and FliA] (Mus musculus) PubMed

 8350.

Overexpression of ZmWri1a increases the fatty acid content of the mature maize grain and the content of certain amino acids, of several compounds involved in amino acid biosynthesis, and of two intermediates of the tricarboxylic acid cycle.[ZmWri1a] (Mus musculus) PubMed

 8351.

These findings suggest a diversified and conserved switch of PTC1/MS1 in regulating programmed male reproductive development in both dicots and monocots.[PTC1] (Mus musculus) PubMed

 8352.

Diffusible factors released by Glomus intraradices induce OsCPK18 and OsCPK4 expression in rice roots.[OsCPK18] (Mus musculus) PubMed

 8353.

These results demonstrated the molecular adaptation of parasite NDKbs in order to exert their biological functions intra-parasite and when secreted by regulating ATP levels of host cells.[NDKb] (Mus musculus) PubMed

 8354.

Tyr10 is criticle for the catalytic activity of BceC . [BceC] (Mus musculus) PubMed

 8355.

Data show that Cr-DapL L,L-diaminopimelate aminotransferase was dimeric in both solution and when crystallized: [DapL] (Mus musculus) PubMed

 8356.

Structure of PomAB revealed two arm domains connected to a large base made of the transmembrane and cytoplasmic domains. [PomA, PomB] (Mus musculus) PubMed

 8357.

OzT8 confers ozone tolerance via stress avoidance. [OzT8] (Mus musculus) PubMed

 8358.

the CRE1 regulatory range in Trichoderma reesei [CRE1] (Mus musculus) PubMed

 8359.

OsSpo11-4 exhibited double-strand DNA cleavage activity and its enzymatic activity appears dependent on Mg(2+) and independent of OsTopVIB, despite its interaction with OsTopVIB.[OsSpo11-4, OsTopVIB] (Mus musculus) PubMed

 8360.

The data suggest that the Rad3 helicase in C. albicans is the product of the orf19.7119 gene. (Mus musculus) PubMed

 8361.

These data highlight the importance of PERK eIF2alpha kinase-dependent eIF2alpha phosphorylation in the intracellular development of Leishmania.[PERK & eIF2alpha] (Mus musculus) PubMed

 8362.

XlnR is highly phosphorylated when it is active in transactivation [XlnR] (Mus musculus) PubMed

 8363.

Periplasmic PomB fragments form a homodimer and that deletions in the PomB linker region cause growth impairment of the cells. [PomB] (Mus musculus) PubMed

 8364.

Sgp2 is not associated with the major pilus subunit Sgp1 in the absence of SrtG. [Sgp2, SrtG] (Mus musculus) PubMed

 8365.

The lack of urease activity in vitro is not solely due to the amber codon in ureD. [UreD] (Mus musculus) PubMed

 8366.

Esp PAI is a self-transmissible element that requires the IntA integrase contained on this element for excision. [IntA, Esp] (Mus musculus) PubMed

 8367.

This is the first report detailing complete plasmepsin 4 gene analysis from Indian P. vivax isolates.[PM4] (Mus musculus) PubMed

 8368.

A hwp2 null mutant is more susceptible to increasing doses of hydrogen peroxide, unable to adhere efficiently to epithelial and endothelial cell lines and unable to form wild type biofilm levels.[hwp2] (Mus musculus) PubMed

 8369.

Experimental evidence that SauUSI, a gene nearly identical to those found in S. aureus strains SA564 and UAMS-1, is a modification-dependent restriction enzyme that requires ATP or dATP for endonuclease activity. (Mus musculus) PubMed

 8370.

The results presented in here suggest that GP63 protease plays a vital role in Trichomonas vaginalis infection process, but may not be related to the adherence of parasitic cells to their hosts.[GP63] (Mus musculus) PubMed

 8371.

[VacA] Chronic infection of VacA-positive Helicobacter pylori may increase the risk for atrial fibrillation by inducing systemic inflammation. (Mus musculus) PubMed

 8372.

The role of infectious bursal disease virus proteins in the activation of the P85alpha subunit of phosphatidylinositol 3-kinase and akt proto-oncogene are reported.[AKT] (Mus musculus) PubMed

 8373.

The authors propose that as animals enter fertile adulthood, EGF signalling switches the mechanism for maintaining protein homoeostasis to an approach involving protein elimination via augmented ubiquitin proteasome system activity.[EGF] (Mus musculus) PubMed

 8374.

Results suggest that the uncommon recognition determinant of two closely spaced tyrosines is a limiting factor in NFAT signaling via Syk association with Vav1 [Vav1]. (Mus musculus) PubMed

 8375.

Ccrp59 and Ccrp1143 are essential for the maintenance of proper cell shape. [Ccrp59; Ccrp1143] (Mus musculus) PubMed

 8376.

The chlamydia-specific hypothetical protein CT311 was detected both inside and outside of the chlamydial inclusions in Chlamydia trachomatis-infected cells.[CT311] (Mus musculus) PubMed

 8377.

From this study it is evident that VPg can serve as a specific regulator of potato virus A expression by boosting the viral RNA amounts as well as the accumulation of viral translation products.[VPg] (Mus musculus) PubMed

 8378.

PaaR is a repressor that controls the expression of the two operons composing the paa gene cluster in vitro. [PaaR] (Mus musculus) PubMed

 8379.

VarS/VarA two-component system acts on a component of the phosphorelay pathway upstream of HapR to regulate HapR expression levels. [VarS, VarA, HapR] (Mus musculus) PubMed

 8380.

The resulting HypF-N mutants have higher contents of alpha-helical structure at the site(s) of mutation in their pH-unfolded states, but such an increase does not correlate with a change of aggregation rate. [HypF-N] (Mus musculus) PubMed

 8381.

Overexpression of ZmCCA1 functionally delays flowering in Arabidopsis.[CCA1] (Mus musculus) PubMed

 8382.

Ska3/Rama1, occupies a unique domain in the outer kinetochore.[Ska3] (Mus musculus) PubMed

 8383.

Our data demonstrate that CcpA has a significant effect on the capsule synthesis and virulence properties of S. suis. [CcpA] (Mus musculus) PubMed

 8384.

These studies identified a number of potential sites of regulation within Atg1 and will serve as a framework for future work with this enzyme.[Atg1] (Mus musculus) PubMed

 8385.

Neither pyruvate : ferredoxin oxidoreductase (PFO) nor hydrogenase localize to the mitosome, but are mostly found in the cytosol. [PFO, hydrogenase] (Mus musculus) PubMed

 8386.

The specific binding component for prostaglandin F(2alpha) (PGF(2alpha)) that exists in the plasma membrane fraction of the oviduct uterus myometrium of laying hens was shown to possess receptor properties for PGF(2alpha).[PGF2alpha receptor] (Mus musculus) PubMed

 8387.

crystal and molecular structures of the LL-diaminopimelate aminotransferase ) in the apo-form and the pyridoxal-5'-phosphate-bound form [LL-diaminopimelate aminotransferase] (Mus musculus) PubMed

 8388.

Here, we solved the N5 structure, the last unknown structure group 1 serotype with a unique Asn147 residue in its 150-loop, demonstrating that it has an extended 150-cavity that closes upon inhibitor binding [neuraminidase] (Mus musculus) PubMed

 8389.

study reports crystal structure of a Foldtype II d-serine deaminase and describes features of the active site essential for catalysis [d-serine deaminase ] (Mus musculus) PubMed

 8390.

These data are consistent with rhesus cytomegalovirus Rh178 blocking protein translation of MHC-I heavy chains at a step prior to the start of translocation, thereby downregulating MHC-I at a very early stage of translation. (Mus musculus) PubMed

 8391.

study describes that the possession of cytochrome c oxidoreductase (SOR)and the ability to utilize sulphite as an electron donor significantly influences bacterial motility, gene regulation, autoagglutination and the invasiveness of C. jejuni [SOR] (Mus musculus) PubMed

 8392.

APx-R is structurally related to ascorbate peroxidases and is targeted to the chloroplast and mitochondria in rice. (Mus musculus) PubMed

 8393.

These findings suggest that Staphylococcus aureus colony spreading requires the expression of agr, which is positively regulated by environmental carbon sources.[agr] (Mus musculus) PubMed

 8394.

Lzap regulates cell cycle progression, doming, and zebrafish epiboly.[Lzap protein, zebrafish] (Mus musculus) PubMed

 8395.

Fsr mediates Ace surface levels through its regulation of the metalloprotease gelatinase (GelE), which we showed directly cleaves Ace, subsequently impacting the ability of cells to adhere to collagen. [GelE, Ace] (Mus musculus) PubMed

 8396.

Absence of RNase III leads to a significant increase in PNPase levels. [PNPase] (Mus musculus) PubMed

 8397.

findings clearly indicate that the origin of NP determines Mx sensitivity and that human influenza viruses acquired adaptive mutations to evade MxA restriction [NP, H5N1 virus, H1N1 Virus] (Mus musculus) PubMed

 8398.

results identify the cooperation between PB2 and PB1 as an important restricting factor for reassortment of in fl uenza viruses[PB1,PB2] (Mus musculus) PubMed

 8399.

The tyrosine phosphatase homolog CtpA is necessary for viability in Caulobacter. One function of CtpA is to regulate PG biosynthesis or remodeling via dephosphorylation of tyrosine residues on target proteins. [CtpA] (Mus musculus) PubMed

 8400.

MnSOD of E. faecalis contributes to survival of the bacterium in microglial cells by influencing their antimicrobial activity. [MnSOD] (Mus musculus) PubMed

 8401.

SpiA gene is involved in both biofilm formation and virulence of S. enteritidis. [spiA] (Mus musculus) PubMed

 8402.

TaCab1 is involved in the plant-pathogen recognition, symptom development, and the basal tolerance to biotic and abiotic stresses through the salicylic acid signaling pathway.[TaCab1] (Mus musculus) PubMed

 8403.

Trm9p and Trm112p function together at the final step in formation of mcm(5)U in tRNA by using the intermediate cm(5)U as a substrate.[trm9] (Mus musculus) PubMed

 8404.

Relative to the wild-type Tx/91-induced gene expression, the NS1 mutant virus induced enhanced expression of innate immune genes, specifically NF-kappaB signalling-pathway genes and IFN-alpha and -beta target genes. (Mus musculus) PubMed

 8405.

Trypanosoma-Sub2 (Tryp-Sub2) is a component of mRNA transcription/export pathway in trypanosomes [TcSub2] (Mus musculus) PubMed

 8406.

The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes. (Mus musculus) PubMed

 8407.

show that two orthodenticle genes, otd1 and otd2, and hunchback act as maternal anterior patterning genes in the honeybee (Mus musculus) PubMed

 8408.

MreB has a role in cell shape determination and binds directly to the cell membrane. (Mus musculus) PubMed

 8409.

structure and nucleotide specificity of dihydrodipicolinate reductase [DapB] (Mus musculus) PubMed

 8410.

The ability of the Sup35 and PrP repeats to support [PSI(+)] propagation stems from their amino acid composition, not their primary sequences.[Sup35] (Mus musculus) PubMed

 8411.

Centromere-bound Scm3 aids recruitment of Cse4/H4 to assemble and maintain an H2A/H2B-deficient centromeric nucleosome. [Scm3] (Mus musculus) PubMed

 8412.

Taken together, these findings suggest that MOPICE modulates the anti-monkeypox virus immune response and that this protein is not the sole virulence factor of the central African clade of monkeypox virus.[MOPICE] (Mus musculus) PubMed

 8413.

Virus with PB2 D253N and Q591K induced more tumor necrosis factor alpha (TNF-alpha) in human macrophages, replicated better in differentiated normal human bronchial epithelial (NHBE) cells, and was more pathogenic for mice.[PB2] (Mus musculus) PubMed

 8414.

The results suggest that expression of L of the DA strain of Theiler's murine encephalomyelitis virus plays an important role in the pathogenesis of Theiler's murine encephalomyelitis virus-induced demyelinating disease. (Mus musculus) PubMed

 8415.

OsHDT1 may be involved in epigenetic control of parental genome interaction for differential gene expression.[OsHDT1] (Mus musculus) PubMed

 8416.

The crystal structure of full length RrgB, solved by X-ray crystallography at 2.8 A resolution, is reported. (Mus musculus) PubMed

 8417.

crystal of glucokinase in complex with glucose belonged to space group P6(2)22 or P6(4)22, with unit-cell parameters a = b = 109.19, c = 141.18 A. The crystal contained one molecule in the asymmetric unit[glucokinase ] (Mus musculus) PubMed

 8418.

SucR was identified as the fourth transcriptional regulator involved in expression control of the adhA gene.[SucR] (Mus musculus) PubMed

 8419.

shows that miR-200 activity is required for taste bud formation and in particular for Calb2b(+) cell formation[miR-200 ] (Mus musculus) PubMed

 8420.

[Cph1; cyanobacterial phytochrome 1] This study describes the effects of divalent cations, pH, and light on the regulation of the autokinase activity of Cph1 and the subsequent control of phosphotransfer to the cognate response regulator Rcp1. (Mus musculus) PubMed

 8421.

The binding of protein phosphatase 1 to the evolutionarily conserved RVSF motif of the kinetochore protein Spc105 is essential for viability by silencing the spindle assembly checkpoint. [Spc105] (Mus musculus) PubMed

 8422.

three cytoskeletonrelated proteins, ARP3, ANXA1, and ANXA5, have been identified as being differentially regulated, in response to dietary change. [ARP3 and ANXA1 and ANXA5] (Mus musculus) PubMed

 8423.

This study therefore expands the versatile nature of the NS1 protein in inhibiting interferon responses at multiple levels, by demonstrating for the first time that it occurs in a manner dependent on allele type. (Mus musculus) PubMed

 8424.

The authors suggest that the sensory box protein, SO3389, is an O2/redox sensor that is involved in optimization of aerobic growth and transitions to anoxia in Shewanella oneidensis MR-1.[SO3389] (Mus musculus) PubMed

 8425.

The authors conclude that GRD1 represents a novel enhancer of cellulase gene expression, which by coregulation with the major cellulase may act via optimization of inducing mechanisms.[GRD1] (Mus musculus) PubMed

 8426.

The authors conclude that the dispersion of ND10 by major immediate-early protein 1 (IE1) appears not to be important for murine cytomegalovirus replication in a mouse-cell culture.[IE1] (Mus musculus) PubMed

 8427.

Secondary envelopment did not proceed in the absence of functional M94, and capsids subsequently accumulated in the center of the cytoplasmic assembly complex.[M94] (Mus musculus) PubMed

 8428.

(pyrrolysine tRNA synthetase) The origin of allostery and half-sites reactivity of activated pyrrolysine tRNA synthetase lies in subtle rearrangements of interactions and dynamics at a global level. (Mus musculus) PubMed

 8429.

To examine the potential functional role of food vacuole-associated enolase, the authors showed the ability of the enolaseto complement a mutant Saccharomyces cervisiae strain deficient in enolase activity.[enolase] (Mus musculus) PubMed

 8430.

The Schizosaccharomyces pombe WISH/DIP/SPIN90 ortholog dip1p is an actin-patch protein that regulates the temporal sequence of endocytic events. [dip1p] (Mus musculus) PubMed

 8431.

The purified protein demonstrated transketolase activity with K(m) values of 0.2mM and 0.8mM respectively for xylulose 5-phosphate and ribose 5-phosphate.[transketolase] (Mus musculus) PubMed

 8432.

Homology modeling of the LmTRYP6 was proposed to predict some functional property of this protein.[TRYP6] (Mus musculus) PubMed

 8433.

In this study the authors show that, upon oxidative stress, Aft1 is transitorily internalized into the nucleus, followed by transcription activation of components of its regulon. (Mus musculus) PubMed

 8434.

These results demonstrate that GRASP, a protein involved in unconventional protein secretion, is also required for polysaccharide secretion and virulence in Cryptococcus neoformans.[GRASP] (Mus musculus) PubMed

 8435.

cellular IRF5 and vIRF3 interact, leading to the functional modulation of IRF5-mediated type I IFN expression and cell cycle regulation [IRF3] (Mus musculus) PubMed

 8436.

rbMATE1 is a multispecific organic cation H(+) exchanger (Mus musculus) PubMed

 8437.

These results suggest that OsPLDalpha is involved in salt tolerance in rice through the mediation of H(+)-ATPase activity and transcription.[OsPLDalpha, H+ ATPase] (Mus musculus) PubMed

 8438.

Spectroscopic, electrochemical, and crystallographic results of IsdI are reported that provide evidence that this heme ruffling is essential to the catalytic activity of the protein.[IsdI] (Mus musculus) PubMed

 8439.

The Galpha subunit of the heterotrimeric G protein complex from wheat (Triticum aestivum), GA3, and the calcium-binding protein, Clo3 which functions to enhance the GTPase activity of GA3. [GA3] (Mus musculus) PubMed

 8440.

These results identify the binding of RON2 to the hydrophobic pocket of AMA1 as the step that commits Plasmodium merozoites to red blood cell invasion and point to RON2 as a potential vaccine candidate.[AMA1, RON2] (Mus musculus) PubMed

 8441.

Nell-1 genes could promote new bone formation and maturation in the rabbit maxillary sinus model. (Mus musculus) PubMed

 8442.

TORC1 can be substantially, if not fully, reactivated in an autophagy-dependent manner under ongoing starvation.[TORC1] (Mus musculus) PubMed

 8443.

the unique folding of this conserved Sir3 AAA(+) domain generates novel surface regions that mediate Sir3-Sir4 and Sir3-nucleosome interactions [Sir3 and Sir4; strain not in database] (Mus musculus) PubMed

 8444.

Catalase and superoxide dismutase-2 are particularly important for diapause female survival; elevation of catalase also contributes to protection of the ovaries. RNAi directed against forkhead transcription factor suppressed both enzymes.[Cat,Sod-2] (Mus musculus) PubMed

 8445.

identification of a NCgl2130 gene of C. glutamicum as a novel succinate exporter that functions in succinate production, and designated sucE1 [sucE1] (Mus musculus) PubMed

 8446.

aaNAT1 is more abundant in Ae. aegypti larval/pupal body, and aaNAT2 is more abundant in the head of adults. It appears that aaNAT1 is mainly involved in sclerotization and aaNAT2 in neurotransmitter inactivation.[aaNAT1,aaNAT2] (Mus musculus) PubMed

 8447.

The calcineurin B-like protein-interacting protein kinases CIPK14 and CIPK15 reduced ROS production and regulate defense responses. [CIPK14, CIPK15] (Mus musculus) PubMed

 8448.

Constituent-based models with an anisotropic elastin part characterize more accurately the mechanical properties of the arterial wall.[Elastin] (Mus musculus) PubMed

 8449.

These results suggest that IR2 protein function requires the two N-terminal domains for binding DNA and TFIIB as well as the C-terminal residues 707 to 1116 containing the TBP-binding domain.[IR2] (Mus musculus) PubMed

 8450.

we report a novel double Ig IL-1R related molecule (DIGIRR) from three model fish (Tetraodon nigroviridis, Gasterosteus aculeatus, and Takifugu rubripes) (Mus musculus) PubMed

 8451.

membrane cholesterol plays an essential role in the binding of C. jejuni CDT subunits to membrane rafts, which promotes the pathogenic events in host cells[cdta, cdtb,cdtc] (Mus musculus) PubMed

 8452.

These results suggest that the p300-acetylated lysines of BTas are important for transactivation of bovine foamy virus promoters and therefore have an important role in bovine foamy virus replication.[BTas] (Mus musculus) PubMed

 8453.

S. Typhi STY1365 encodes a holin remnant protein that is involved in the stability of the bacterial envelope [STY1365; different strain] (Mus musculus) PubMed

 8454.

cloning and characterization of Francisella tularensis MEP cytidylyltransferase [MEP cytidylyltransferase] (Mus musculus) PubMed

 8455.

The results showed that NS1 of avian influenza virus H5N1 (A/chicken/Guangdong/1/2005) is able to bind to PSD-95, whereas NS1 of human influenza virus H1N1 (A/Shantou/169/2006) is unable to do so.[NS1] (Mus musculus) PubMed

 8456.

human proximal tubule epithelial cell line, HK-2 cells, are differentially susceptible to the cytotoxic action of Shiga Toxin Types 1 and 2. [Stx1] and [Stx2] (Mus musculus) PubMed

 8457.

Genetic analysis of LB4D indicated that the dwarf phenotype was controlled by a single semidominant dwarfing gene, which was named LB4D.[LB4D] (Mus musculus) PubMed

 8458.

The relationship between oxygen input, physiology and gene expression of E. coli MG1655 and two isogenic mutants lacking succinate dehydrogenase (SDH) and fumarate reductase (FRD) activities was analyzed at different aerobiosis levels.[sdhC, frdA] (Mus musculus) PubMed

 8459.

At day 7 and later, expression of cpo was much higher in diapausing vs. non-diapausing adults. In 2-month old diapause females transferred to diapause-terminating conditions, cpo expression declined.[cpo] (Mus musculus) PubMed

 8460.

the TaSnRK2.7-A genomic region has evolved under extensive selection pressure during crop breeding [SnRK2.7-A] (Mus musculus) PubMed

 8461.

suggesting that OsAM1 plays a fundamental role in building the proper chromosome structure at the beginning of meiosis[AM1] (Mus musculus) PubMed

 8462.

These measurements support a cofilin-severing mechanism in which mechanical asymmetry promotes local stress accumulation and fragmentation at boundaries of bare and cofilin-decorated segments, analogous to failure of some nonprotein materials.[Cofilin] (Mus musculus) PubMed

 8463.

Data indicate that p13 protein directly binds Tax, decreases Tax binding to the CBP/p300 transcriptional coactivator, and, by reducing Tax transcriptional activity, suppresses viral expression: [p13] (Mus musculus) PubMed

 8464.

Neither Glu-286 nor active-site water likely constitutes the gating element proton pumping in cytochrome c oxidase.[Cco] (Mus musculus) PubMed

 8465.

mechanism of oxygen reactivity in a heme and tyrosyl radical-containing fatty acid alpha-(di)oxygenase [fatty acid alpha-(di)oxygenase] (Mus musculus) PubMed

 8466.

Expression analysis in 16 different tissues of fifth instar larvae and functional prediction using InterProScan suggested that BGIBMGA003864 was most likely to be the gene responsible for the sex-linked translucent (os) phenotypes. [BGIBMGA003864] (Mus musculus) PubMed

 8467.

CagA in the stomach plays an important role in the migration of H. pylori-primed CD4(+) T cells in the gastric mucosa. [CagA] (Mus musculus) PubMed

 8468.

this study shows the essentiality of T. brucei Stearoyl-CoA desaturase (SCD)[SCD] (Mus musculus) PubMed

 8469.

A total of 441 differentially expressed genes, designated as XDGs (Xa21 mediated differentially expressed genes), were identified.[Xa21] (Mus musculus) PubMed

 8470.

In developing ovaries, copy number of treh-2 mRNA per 1 copy of rp49 mRNA was 1000x higher than that of treh-1 mRNA. Trehalase activities enhanced by diapause hormone originate from treh-2 protein regulated at the transcriptional level.[diapause hormone] (Mus musculus) PubMed

 8471.

two redundant genes, OsSUS5 and OsSUS7, evolved via duplication of a chromosome region and through the transposition of transposable elements. [OsSUS5 and OsSUS7] (Mus musculus) PubMed

 8472.

BEST1 is a functional anion channel in the plasma membrane. [BEST1] (Mus musculus) PubMed

 8473.

Spore production for ugtADelta was reduced to 1%, and spore germination was reduced to half. [ugtA] (Mus musculus) PubMed

 8474.

Iwr1 plays an important role in preinitiation complex formation by all three nuclear RNA polymerases [Iwr1] (Mus musculus) PubMed

 8475.

this study suggests that NleC is a unique virulence factor that impacts several aspects of in fl ammatory signaling [NleC] (Mus musculus) PubMed

 8476.

Data suggest that TaMYB4 negatively regulates the lignin biosynthesis in wheat: [TaMYB4] (Mus musculus) PubMed

 8477.

Heme-L-lysinate could attenuate atherosclerotic progression through upregulating HO-1 and HSP70 expression and increasing CO production. [HSP70] (Mus musculus) PubMed

 8478.

local and global thermodynamic stability of the variant (1-165) of SlyD from Escherichia coli [SlyD] (Mus musculus) PubMed

 8479.

Results describe the molecular analysis of partial cDNA sequences of sheep Peg10 and Xist. (Mus musculus) PubMed

 8480.

Silencing of MtSAP1 by RNA interference (RNAi) showed that the function of the encoded protein is required for adequate accumulation of storage globulin proteins, vicilin and legumin, and for the development of embryos... [SAP1] (Mus musculus) PubMed

 8481.

TheHra2 deletion mutant was deficient in adherence but not autoaggregation or invasion, pointing to a functional distinction from the autoagglutinin Hra1 and the Tia invasin.[Hra2] (Mus musculus) PubMed

 8482.

Deletion of the SIT4 gene, which encodes for the catalytic subunit of type 2A ceramide-activated protein phosphatase in yeast, abolished the premature ageing and hydrogen peroxide sensitivity of isc1Delta cells.[SIT4 & isc1] (Mus musculus) PubMed

 8483.

In a FRQ-sufficient background, the UV90 mutation causes damping of the free-running conidiation rhythm, reduction of the amplitude of the FRQ [Frequency] protein rhythm, and increased phase-resetting responses to both light and heat pulses.[FRQ] (Mus musculus) PubMed

 8484.

An hlyU mutant was constructed, which exhibited an approximately 5-fold decrease in hemolytic activity on sheep blood agar with no statistically significant decrease in cytotoxicity of the wild-type strain.[hlyU] (Mus musculus) PubMed

 8485.

The authors showed that purified YefM(Spn) antitoxin and the YefM-YoeB(Spn) toxin-antitoxin protein complex bind to a palindrome sequence encompassing the -35 region of the main promoter (P(yefM2)) of the operon.[YoeB] (Mus musculus) PubMed

 8486.

These results suggest that m- and micro-calpain may be involved in colon epithelial cell death induced by E. histolytica.[m-calpain, micro-calpain] (Mus musculus) PubMed

 8487.

OsPT8 is involved ininorganic phosphate homeostasis in rice and is critical for plant growth and development.[OsPT8] (Mus musculus) PubMed

 8488.

Mutagenesis of the interchange thiol of NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase (2-KPCC) abolished all redox-dependent reactions of 2-KPCC (2-KPC carboxylation or protonation).[2-KPCC] (Mus musculus) PubMed

 8489.

relative expression levels of IgD, IgM, and IgZ/T were measured in triplicate for zebrafish (Mus musculus) PubMed

 8490.

Determined is the crystal structure of E.coli MnmC containing flavin adenine dinucleotide, at 3.0 A resolution. [MnmC] (Mus musculus) PubMed

 8491.

The authors demonstrate that the Streptococcus pyogenes FbaB is essential and sufficient to trigger endothelial cell invasion via a Rac1-dependent phagocytosis-like uptake.[FbaB] (Mus musculus) PubMed

 8492.

Gem1 ortholog Miro-1 localizes to sites of endoplasmic reticulum-mitochondrial contact, suggesting that some of the features ascribed to Gem1 may be evolutionarily conserved.[Gem1] (Mus musculus) PubMed

 8493.

The complete attenuation of the SDH mutant for virulence in the mouse model and increased virulence mutant strains postcomplementation with SDH, indicated that the SDH surface export indeed regulates virulence.[SDH] (Mus musculus) PubMed

 8494.

These results suggest that OsREC8 has several essential roles in the meiotic processes.[OsREC8] (Mus musculus) PubMed

 8495.

Mg(2+) and Ca(2+) transport via OsHKT2;4 may be small and would depend on competing K(+) concentrations in plants.[OsHKT2;4] (Mus musculus) PubMed

 8496.

The authors show that all four RAD51 paralogues act in DNA repair and recombination, though not equivalently, while mutation of only one RAD51 paralogue gene significantly impedes variant surface glycoprotein switching.[RAD51] (Mus musculus) PubMed

 8497.

The expression patterns of miR-2b and P25 gene indicate that miR-2b might act as a fine-tuning regulator of expression of the P25 gene at the post-transcriptional level.[microRNA-2b] (Mus musculus) PubMed

 8498.

It is shown that a member of the TetR family of transcriptional regulators (SACE_7040 homolog) is an important regulator of the morphological differentiation of Saccharopolyspora erythraea. (Mus musculus) PubMed

 8499.

These data indicate that CDC15 regulates hyphal growth and asexual development for the pathogenic development of M. orzyae. [CDC15] (Mus musculus) PubMed

 8500.

Wheat, barley, maize, and rice all possess purple acid phosphatase (PAP) genes that, expressed in Pichia pastoris, give fully functional phytases (PAPhys) with very similar enzyme kinetics.[PAP] (Mus musculus) PubMed

 8501.

LTN1 is a crucial phosphate (Pi) starvation signaling component downstream of miR399 involved in the regulation of multiple Pi starvation responses in rice.[LTN1] (Mus musculus) PubMed

 8502.

Cwht1p crystals were grown and subjected to X-ray irradiation, giving a complete diffraction dataset to 2.04 A resolution. [Cwht1p] (Mus musculus) PubMed

 8503.

Roc5 negatively regulates bulliform cell fate and development.[Roc5] (Mus musculus) PubMed

 8504.

Findings support the notion of a central role for Puf2 in parasite latency during switch between the insect and mammalian hosts [Puf2]. (Mus musculus) PubMed

 8505.

Csn2 is a ds-DNA-binding protein functioning at the quaternary structure level and regulated by Ca(2+) ions [Csn2] (Mus musculus) PubMed

 8506.

The authors observed that beta-sheet and coiled-coil domains in the N-terminal moiety of SiiE are required for the control of SiiE retention on the surface and co-ordinated release.[SiiE] (Mus musculus) PubMed

 8507.

Rice ATP binding cassette (ABC)-type transporter, ABCG43, is Cadmium inducible and confers cadmium tolerance on yeast. (Mus musculus) PubMed

 8508.

Inactivation of pulA, a MalR regulated gene which encodes a cell surface carbohydrate binding protein, significantly reduced GAS human epithelial cell adhesion and mouse oropharyngeal.[pulA & MalR] (Mus musculus) PubMed

 8509.

Both Fet31 and Fet34 localize to the yeast plasma membrane and both support iron uptake along with Ftr1 protein.[Fet31 & Fet34 & Ftr1] (Mus musculus) PubMed

 8510.

aph(3")-IIIa was present in 22 strains of methicillin resistant staphylococcus aureus. [aph(3")-IIIa] (Mus musculus) PubMed

 8511.

The authors show that postreplication repair (PRR) of newly synthesized DNA in UV-damaged yeast cells is inhibited in the absence of Mec1 and Rad53 proteins.[Mec1 and Rad53] (Mus musculus) PubMed

 8512.

These data show that LSA-1 plays a critical role during late liver-stage schizogony and is thus important in the parasite transition from the liver to blood.[LSA-1] (Mus musculus) PubMed

 8513.

The authors propose that CTL843 acts as a S-adenosylmethionine/S-adenosylhomocysteine transporter (SAMHT) allowing Chlamydia to acquire S-adenosylmethionine from the host cell and excrete the toxic by-product S-adenosylhomocysteine.[CTL843] (Mus musculus) PubMed

 8514.

NanS, a carbohydrate esterase that is shown in this study to deacetylate the 9 position of 9-O-sialic acid. [NanS] (Mus musculus) PubMed

 8515.

Quantitative RT-PCR revealed that transcription of the bursicon monomers, burs and pburs, steadily increases through the larval stages, peaks in the black pupa stage, and decreases to below detectable levels by 8 h after adult ecdysis.[bursicon] (Mus musculus) PubMed

 8516.

A gene responsible for tolerance to boron (B) toxicity in rice (Oryza sativa), named BORON EXCESS TOLERANT1, was identified.[BET1] (Mus musculus) PubMed

 8517.

ABL1 modulates abscissic acid (ABA) and auxin responses by directly regulating the ABA-responsive elements containing genes. (Mus musculus) PubMed

 8518.

Role of four calcium transport proteins, encoded by nca-1, nca-2, nca-3, and cax, in maintaining intracellular calcium levels in Neurospora crassa (Mus musculus) PubMed

 8519.

These experiments demonstrate that inhibition of SID1 expression in vivo reduces the virulence of Histoplasma capsulatum yeasts.[SID1] (Mus musculus) PubMed

 8520.

The authors provide evidence that the beta' zipper, an evolutionarily conserved loop of the largest subunit of RNA polymerase core, interacts with promoter spacer, a DNA segment that separates the -10 and -35 promoter elements. (Mus musculus) PubMed

 8521.

Nop8p may control the exosome function during pre-rRNA processing [Nop8p] (Mus musculus) PubMed

 8522.

Lysine 99 contributes 2.79 and 2.6 kcal/mol to Lys and alpha-ketoglutarate binding, and 1.85 kcal/mol to binding NADH, respectively.[saccharopine dehydrogenase] (Mus musculus) PubMed

 8523.

the nascent antizyme polypeptide OAZ1 is the relevant polyamine sensor that operates in cis to negatively regulate upstream ribosomal frameshifting on the polysomes, where its own mRNA is being translated [OAZ1] (Mus musculus) PubMed

 8524.

Cdc15 functions as a coincidence detector of two essential cell cycle oscillators: the Polo kinase Cdc5 synthesis/degradation cycle and the Tem1 G-protein cycle [cdc15, Tem1, and Polo; strain 2303] (Mus musculus) PubMed

 8525.

These results demonstrate that the amino acid at position 109 in NP enhances viral RNA synthesis and the pathogenicity of highly pathogenic avian influenza viruses.[NP] (Mus musculus) PubMed

 8526.

The cysteine-rich protein (CRP) of potato virus M inhibited both local and systemic silencing, whereas the triple gene block protein 1 (TGBp1) showed suppressor activity only on systemic silencing.[CRP & TGBp1] (Mus musculus) PubMed

 8527.

The observed reduced virus production in salivary glands could be reverted by repair of the frameshift mutation in MCK-2 protein. (Mus musculus) PubMed

 8528.

The data support the conclusion that D10Deltagdha parasites are not experiencing enhanced oxidative stress and that GDHa function may not be the provision of NADP(H) for reductive reactions.[gdha] (Mus musculus) PubMed

 8529.

This in vivo study validates Kaposi's sarcoma-associated herpesvirus miR-K12-11 as a functional ortholog of miR-155 in the context of hematopoiesis and suggests a novel mechanism by which KSHV miR-K12-11 induces splenic B-cell expansion. (Mus musculus) PubMed

 8530.

The data demonstrates that Goa1p is required for mitochondrial functions, especially complex I activity, and, as a consequence, is critically important in maintaining nontoxic levels of reactive oxidant species (goa1). (Mus musculus) PubMed

 8531.

The results suggest that Cdc20p and Cdh1p may be anaphase-promoting complex/cyclosome APC/C activators that are important for mitosis but also morphogenesis in C. albicans (Cdc20 and Cdh1). (Mus musculus) PubMed

 8532.

Examination of the kinetic mechanisms of interactions of the strong DNA-binding subsite and the total DNA-binding site of the ASFV pol X with the ssDNA, and energetics of the intermediate formations (polymerase X). (Mus musculus) PubMed

 8533.

Examination of the energetics of interactions of the total DNA-binding site and the strong DNA-binding subsite of the ASFV pol X with the ssDNA (polymerase X). (Mus musculus) PubMed

 8534.

Data indicates that actin plays a major role in the orderly traffic and localization of CHS-1 at the hyphal apex (chitin synthase 1). (Mus musculus) PubMed

 8535.

DYF-17 and DYF-18-cellular components important for cilium formation and function (Mus musculus) PubMed

 8536.

The 147C strain of Helicobacter pylori expressing tyrosine-phosphorylated CagA (EPIYA present) induced enhanced MMP-9 secretion by gastric epithelial cells.[CagA] (Mus musculus) PubMed

 8537.

Our results suggest the involvement of RNase G in the processing of the 5'-region of 23S rRNA precursors.[RNaseG] (Mus musculus) PubMed

 8538.

Deletion of saeRS in Staphylococcus epidermidis resulted in an increase in biofilm-forming ability, which was associated with increased extracellular DNA release and up-regulated Aap expression.[saeRS] (Mus musculus) PubMed

 8539.

MpkB MAP kinase is required for some post-karyogamy process as well as at the hyphal anastomosis stage to accomplish sexual development successfully. [MpkB MAP kinase] (Mus musculus) PubMed

 8540.

These results demonstrate that, as in mitosis, Smc5-Smc6 is required to ensure proper chromosome segregation during meiosis.[Smc6, Smc5] (Mus musculus) PubMed

 8541.

Inhibition of Cdc25 by the replication checkpoint is reinforced by degrading any Cdc25 which is not phosphrorylated and/or 14-3-3 bound.[Cdc25] (Mus musculus) PubMed

 8542.

the impact of the F610A mutation on the functionality of AcrB by means of computational techniques [AcrB] (Mus musculus) PubMed

 8543.

TFIIH constitutes a multitarget complex for Ydj1, as six of the seven TFIIH core components contain biologically relevant Ydj1- binding motives.[TFIIH, Ydj1] (Mus musculus) PubMed

 8544.

The amino-terminal conserved, glutamate-rich sequence of herpesvirus saimiri Tip specifically interacts with the human retromer subunit Vps35 and inhibits retromer activity.[Tip] (Mus musculus) PubMed

 8545.

These findings indicate that binding of NS1 to Scribble and Dlg1 functions to disrupt the cellular tight junction and that this effect likely contributes to the severe disease associated with highly pathogenic H5N1 influenza A viruses.[NS1] (Mus musculus) PubMed

 8546.

Trypanosoma brucei RGG2, directly binds mRPN1 and is thought to modulate guide RNA utilization by editing complexes[mitochondrial RNA precursor-processing endonuclease 1] (Mus musculus) PubMed

 8547.

graX, also involved in cationic antimicrobial peptide resistance and cotranscribed with graRS, encodes a regulatory cofactor of the GraSR signaling pathway.[GraS, GraR] (Mus musculus) PubMed

 8548.

The stability and folding relaxation rate of phosphoglycerate kinase (PGK) Forster resonance energy transfer (FRET) constructs localized in the nucleus or in the endoplasmic reticulum (ER) of eukaryotic cells, was measured.[PGK] (Mus musculus) PubMed

 8549.

Intrinsic HIV-2 integrase variation at "secondary" HIV-1 integrase inhibitor-resistance sites may affect the genetic barrier to HIV-2 INI resistance.[Integrase] (Mus musculus) PubMed

 8550.

These data define the importance of a cluster of mutations in the second zinc finger of E6m in increasing the oncogenic potential of human papillomavirus 83.[E6] (Mus musculus) PubMed

 8551.

Orexin A acts as feeding regulator in the zebrafish. (Mus musculus) PubMed

 8552.

VopL stabilizes primarily lateral (short-pitch) contacts between actin monomers to create the base of a two-stranded filament. (Mus musculus) PubMed

 8553.

VopL promotes rapid cycles of filament nucleation and detachment and stabilizes a hexameric double-stranded pointed end nucleus. (Mus musculus) PubMed

 8554.

Here the ion and water molecules are queued by the KscA potassium channel during permeation; their modification is predicted under physiologically relevant conditions. (Mus musculus) PubMed

 8555.

Data indicate that Spb4 is a component of early nucle(ol)ar pre-60S ribosomal particles containing 27SB pre-rRNA. [Spb4] (Mus musculus) PubMed

 8556.

report that four subunits of the Ccr4-Not complex-Ccr4p, Pop2p, Not2p, and Not4p-severely impact HSP104 RNA transcription site-associated retention induced by MFT1 gene deletion[not4] (Mus musculus) PubMed

 8557.

The interactions of Tom22, a multifunctional subunit of the outer membrane translocator TOM40 complex, with other translocator subunits, were analyzed.[Tom22] (Mus musculus) PubMed

 8558.

LacY is oriented physiologically with a closed periplasmic side that limits access of sugar to the binding site.[LacY] (Mus musculus) PubMed

 8559.

Rice DNG701 is a 5-meC DNA glycosylase/lyase responsible for the demethylation of Tos17.[DNG701] (Mus musculus) PubMed

 8560.

LUNA is expressed during HCMV infections. [LUNA] (Mus musculus) PubMed

 8561.

structural and functional analyses reveal that the effector domain of AVR3a contains a conserved, positively charged patch and that this region, rather than the RXLR domain, is required for binding to phosphatidylinositol monophosphates[AVR3a] (Mus musculus) PubMed

 8562.

RolR (ResorcinolRegulator) may represent a new subfamily of TetR proteins that are invovled in aromatic degradation and sharing common recognition mode as for RolR [RolR] (Mus musculus) PubMed

 8563.

CRL5 (crown rootless5) controls the cytokinin signaling pathway. [CRL5] (Mus musculus) PubMed

 8564.

cell-free studies suggest that Mes1 behaves as a pseudosubstrate for Fzr1/Mfr1 but works as a competitive substrate for Slp1[Fzr1] (Mus musculus) PubMed

 8565.

Interaction of WhcA with SpiA is modulated by the redox status of the cell. [WhcA] (Mus musculus) PubMed

 8566.

katanin regulatory subunit in turn caused a dramatic change in the microtubule-binding properties of the N-terminal domain of the catalytic subunit[ katanin ] (Mus musculus) PubMed

 8567.

EYE2 is positioned along, and adjacent to, the daughter four-membered rootlet in the absence of pigment granules[ EYE2 ] (Mus musculus) PubMed

 8568.

Aerobic inactivation of catalytic hydrogen oxidation by the [NiFe]-hydrogenase (HoxEFUYH) is total and nearly instantaneous, producing two inactive states. [HoxEFUYH] (Mus musculus) PubMed

 8569.

(trans-acyltransferase) The X-ray crystal structure of trans-acyltransferase (AT) from "AT-less" disorazole synthase (DSZS) is reported and a model is derived for the selective association of the DSZS AT and its acyl carrier protein substrate. (Mus musculus) PubMed

 8570.

(H-NOX) Structure of the heme pocket of H-NOX family protein highlights the locations of important residues; overview of the distal and proximal pockets reveals hydrogen-bonding network, proximal His-102, and residues associated with heme deformation (Mus musculus) PubMed

 8571.

These results showed that changing the glutamine to a basic arginine residue of Newcastle disease virus fusion protein reduced viral replication and attenuated the pathogenicity of the virus in chickens.[F] (Mus musculus) PubMed

 8572.

Gene polymorphisms and copy number variation was observed in isolates of P. vivax from Southeast Asian countries. In Korean isolates polymorphism is limited to the F1076L variant, and no isolates with high level of resistance were found [pvmdr1;pvcrt-o] (Mus musculus) PubMed

 8573.

These results clearly demonstrate that Sup35p C-terminal domain plays a critical role in prion propagation and provide new insights into the mechanism of prion conversion.[Sup35] (Mus musculus) PubMed

 8574.

These findings suggest that Rho-ROCK signaling could be involved, via a mitochondrial pathway, in the apoptosis-like death of Cryptococcus neoformans induced by the adherence of Staphylococcus aureus.[Rho, Rho-associated coiled-coil forming kinase] (Mus musculus) PubMed

 8575.

The essential role of lipoamide dehydrogenase (LipDH) in bloodstream parasites was confirmed by an in vivo model. Lipdh-/- cells were unable to infect mice.[lipoamide dehydrogenase] (Mus musculus) PubMed

 8576.

Findings suggest that Orf5 are homologs of YscL from Yersinia. They associated with the bacterial membrane and interact with EscN. (Mus musculus) PubMed

 8577.

first PARG crystal structure (derived from the bacterium Thermomonospora curvata), which reveals that the PARG catalytic domain is a distant member of the ubiquitous ADP-ribose-binding macrodomain family [PARG] (Mus musculus) PubMed

 8578.

T2SS is required for V. vulnificus pathogenicity, which is mediated by at least two secreted factors, VvhA hemolysin and VvpE elastase, via facilitating the secretion and exposure of these factors to host cells. [VvhA, VvpE] (Mus musculus) PubMed

 8579.

Stk, a serine/threonine protein kinase activates genes for virulence factors, osmoregulation, metabolism of alpha-glucans, and fatty acid biosynthesis, as well as genes affecting cell wall synthesis. [Stk] (Mus musculus) PubMed

 8580.

The G(S)Z isozyme serves as an ATP phosphoribosyltransferase in histidine biosynthesis when histidine is available; however, HisG(L) also functions as ATP phosphoribosyltransferase, particularly during nitrogen fixation (HisG(L)and HisG(S)Z). (Mus musculus) PubMed

 8581.

MASP52 (mucin-associated surface protein) plays a role in a process whereby the trypomastigote forms of the parasite invade the host. [MASP52] (Mus musculus) PubMed

 8582.

The authors discovered that Helicobacter pylori strains establish bacterial colonies deep in the gastric glands and identified a novel protein, ChePep, necessary to colonize this niche.[ChePep] (Mus musculus) PubMed

 8583.

Data found IolR to be required for the repression of its own gene and for the downregulation of the idhA-encoded myo-inositol dehydrogenase activity in the presence and absence of inositol. [IolR] (Mus musculus) PubMed

 8584.

ASP is effectively expressed from the 3' LTR in infected T cells and localizes to the cell membrane. [Asp] (Mus musculus) PubMed

 8585.

MsmK was identified as an ATPase which energizes multiple carbohydrate transporters in S. pneumoniae [MsmK]. (Mus musculus) PubMed

 8586.

our study suggests that RIP1 has emerged as a molecular switch in triggering cell death or survival in Branchiostoma (Mus musculus) PubMed

 8587.

results demonstrate that phosphodiesterase SmNPP-5 is a virulence factor for schistosomes [SmNPP-5] (Mus musculus) PubMed

 8588.

Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL mRNA expression. [RANKL] (Mus musculus) PubMed

 8589.

Among the residues studied, F270 and Q498 are critical specificity determinants for the distinction of mono- from dicarboxylates, and N501 is a critical residue for transport.[Jen1] (Mus musculus) PubMed

 8590.

Transcriptional activation of maize defence genes in infections with Deltapit1/2 mutant strains indicates that the mutants have a defect in suppressing plant immune responses.[pit1 & pit2] (Mus musculus) PubMed

 8591.

Agr-dependent repression of staphylococcal superantigen-like proteins expression is indirect and mediated by the transcription factor repressor of toxins (Rot).[Rot] (Mus musculus) PubMed

 8592.

BraDE is involved in bacitracin sensing and signalling through BraSR, whereas VraDE acts specifically as a detoxification module and is sufficient to confer bacitracin and nisin resistance.[BraSR, BraDE, VraDE] (Mus musculus) PubMed

 8593.

These data indicate that nuclear shuttling is critical for Ssd1 mRNA binding and Ssd1-mRNA localization in the cytoplasm.[Ssd1] (Mus musculus) PubMed

 8594.

SufB interact with SufC in the apicoplast. [SufB] (Mus musculus) PubMed

 8595.

A new 80 kDa protein, Bombyx mori egg protein 80 (BmEP80) is a component of the eggshell which is secreted by follicle cells during the late vitellogenesis stage to early choriogenesis stage. (Mus musculus) PubMed

 8596.

M18BP1 directly binds CENP-C through conserved domains in the CENP-C protein (M18BP1) (Mus musculus) PubMed

 8597.

The phenotype of temperature-sensitive (ts) mutants of GTF1, a gene proposed to code for subunit F of mitochondrial amidotransferase in Saccharomyces cerevisiae, is described.[Gtf1p] (Mus musculus) PubMed

 8598.

Polzeta and Rev1 are unique among PCNA-interacting proteins in using the novel binding site near the intermolecular interface of PCNA.[PCNA, Polzeta, Rev1] (Mus musculus) PubMed

 8599.

The present findings provide new insights on how MA interacts with CaM that may ultimately help in identification of the functional role of CaM-Gag interactions in the HIV replication cycle.[Matrix protein] (Mus musculus) PubMed

 8600.

In the absence of SPI-2 protein, ectromelia virus is attenuated in mousepox-susceptible mice, resulting in lower viral loads in the liver, decreased spleen pathology, and substantially improved host survival.[SPI-2] (Mus musculus) PubMed

 8601.

Caenorhabditis elegans SNAP-29 is required for organellar integrity of the endomembrane system and general exocytosis in intestinal epithelial cells. (Mus musculus) PubMed

 8602.

Results identify three adiponectin receptor homologs in C. elegans, paqr-1, -2 and -3, and suggest that paqr-1 and paqr-2 regulate fatty acid metabolism and cold adaptation [paqr-1, -2, -3]. (Mus musculus) PubMed

 8603.

The role of CagA dimerization in induction of the hummingbird phenotype, was investigated.[CagA] (Mus musculus) PubMed

 8604.

Genetic deletion of ptpA or ptpB does not affect in vitro growth or cell wall integrity, raising the possibility that PtpA and PtpB have specialized functions during infection.[PtpA & PtpB] (Mus musculus) PubMed

 8605.

These data reveal a novel mechanism for the inhibition of hepatitis B virus replication by cIAP2 via acceleration of the ubiquitin-proteasome-mediated decay of polymerase.[polymerase] (Mus musculus) PubMed

 8606.

HTLV-1 accessory protein p13 binds the SH3 domain of Src family kinases via its carboxyl-terminal proline-rich motif, forming a stable heterodimer that translocates to mitochondria. (Mus musculus) PubMed

 8607.

E. coli O157 : H7-derived flagellin induces rapid phosphorylation of the epidermal growth factor receptor, as an early event in intestinal epithelial cell signalling, and that this is required for the release of the pro-inflammatory cytokine IL-8.[fliC] (Mus musculus) PubMed

 8608.

Each subunit deletion resulted in a reduction in the adhesion to intestinal cells to the same level of laboratory strains, and this effect was restored by complementary plasmids, suggesting that the 4 proteins are necessary for CS6 expression.[CS6] (Mus musculus) PubMed

 8609.

These data define PceT (and more generally the new RdhT family) as a class of TF-like chaperones involved in the maturation of proteins secreted by the twin-arginine translocation pathway.[PceT] (Mus musculus) PubMed

 8610.

Data reveal that Xog1p, originally identified from LL-37 binding, has a role in C. albicans adhesion to polystyrene and, by inference, attach to host cells via direct or indirect manners [Xog1p]. (Mus musculus) PubMed

 8611.

Schizosaccharomyces pombe mcb1(+) (Mcm-binding protein 1), an apparent orthologue of the human MCM-binding protein that associates with a subset of MCM complex proteins.[MCM-BP] (Mus musculus) PubMed

 8612.

Rab11 functions are mediated by evolutionarily conserved and potentially lineage-specific interactions essential for the integration of the endomembrane system. [Rab11] (Mus musculus) PubMed

 8613.

Glycerol 3-phosphate, which is produced in vivo by a glycosome-resident glycerol kinase, mitigated acid inactivation of lysate-derived TbHK activity.[TbHK1] (Mus musculus) PubMed

 8614.

Depletion of the major 5'-3' exoribonuclease, XRNA, resulted in the stabilization of most mRNAs with half-lives under 30 min[5'-3' exoribonuclease ] (Mus musculus) PubMed

 8615.

Bombyx mori flap endonuclease-1 (BmFEN-1) gene consists of seven introns and eight exons that encode a protein with 380 amino acids that has the typical XPG domain. BmFEN-1 can inhibit apoptosis and promote cell proliferation. (Mus musculus) PubMed

 8616.

PIC5 is a novel virulence factor involved in appressorium differentiation and pathogenesis in Magnaporthe oryzae. [PIC5] (Mus musculus) PubMed

 8617.

We observed mutations in vraS and graR during vancomycin non-susceptibility development and novel stop codons in the reverted strain. Mutations in graR appear important for development of intermediate susceptibility to vancomycin. [VraSm GraR] (Mus musculus) PubMed

 8618.

Increaased (E)-beta-caryophyllene synthase gene activity in Zea mays roots upon feeding by larvae of Diabrotica virgifera virgifera [TPS 23] (Mus musculus) PubMed

 8619.

NAR2.1 was mainly expressed in roots and induced by nitrate. NAR2.1 plays a key role in enabling the plant to cope with variable nitrate supply. [NAR2.1] (Mus musculus) PubMed

 8620.

The interaction between the human NimA-like protein kinase Nek9 and the Helicobacter HcpC has been validated by ELISA and surface plasmon resonance. (Mus musculus) PubMed

 8621.

Detailed characterization of a functionally unknown gene (HP986), which was detected in patient isolates, is reported.[HP986] (Mus musculus) PubMed

 8622.

the structural and functional features of mutant GGBP [GGBP] (Mus musculus) PubMed

 8623.

Glycosylation of the CH2/CH3 interface inhibits interaction with the pathogen IgA binding protein SSL7, while maintaining binding of pIgR, essential to the biosynthesis and transport of SIgA.[SSL7] (Mus musculus) PubMed

 8624.

The crystal structure of EF1143 and dynamic light scattering measurements in solution revealed a tetrameric oligomer as the most probable biologically active unit.[EF1143] (Mus musculus) PubMed

 8625.

(H2A.Z) The role of H2A.Z is to facilitate addition and removal of promoter nucleosomes and to prevent formation of unfavorable stable epigenetic chromatin structures. (Mus musculus) PubMed

 8626.

Repression was also more efficient when Pab1p was bound in close proximity to Puf5p.[Puf5p, Pab1p] (Mus musculus) PubMed

 8627.

CIITA inhibit Tax-2 by binding the viral transactivator both directly or through a tripartite interaction with NF-YB in.[Tax-2] (Mus musculus) PubMed

 8628.

[cytidine repressor CytR] Operator-DNA binding of CytR is accompanied by disorder-to-order transition in which the disordered state is an ensemble of distinct conformations. (Mus musculus) PubMed

 8629.

The plant-specific N-terminal domain of CK2beta subunits is involved in the down-regulation of the CK2 holoenzyme activity and in the stabilization of CK2beta1 protein.[CK2beta1] (Mus musculus) PubMed

 8630.

a novel signaling pathway was found by which Cdc28 controls Cbk1 through the regulatory phosphorylation of Mob2, which is crucial for normal hyphal development.[Cdc28] [Cbk1] [Mob2] (Mus musculus) PubMed

 8631.

Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1. [Mrr1] (Mus musculus) PubMed

 8632.

The flagellar localization and membrane association of FCaBP in L. amazonensis suggest that the mechanisms for flagellar targeting, including a specific palmitoyl acyltransferase, are conserved in this organism.[FCaBP] (Mus musculus) PubMed

 8633.

A carbohydrate binding site within GspBBR mediates binding of S. gordonii strain M99 to sialyl-T antigen, and this interaction is important for virulence. (Mus musculus) PubMed

 8634.

From these results, the authors speculate that the Na(+) flux is reduced by the PomB-F22Y mutation, and that PomB-F22 is important for the effective release of Na(+) from PomB-D24.[PomB] (Mus musculus) PubMed

 8635.

The association between the emergence of influenza A/H1N1/09v 222G/N polymorphisms in the hemagglutinin gene and increased virulence was documented. (Mus musculus) PubMed

 8636.

Adherence assays revealed significantly reduced binding of the Deltarga mutant to epithelial HEp-2 cells and to immobilized human keratin 4, respectively.[Rga] (Mus musculus) PubMed

 8637.

Pneumococcal choline-binding protein A (PcpA) plays a critical role in pneumococcal pneumonia. [PcpA] (Mus musculus) PubMed

 8638.

SWI/SNF acts at least in part independently of SOMI-1 to inhibit the supernumerary molt. ; somi-1 coordinates a nuclear response that complements the activity of mir-84 [SWI/SNF; and mir-84] (Mus musculus) PubMed

 8639.

a ternary crystal complex structure of Escherichia coli Hfq bound to a major Hfq recognition region on DsrA (AU(6)A) together with ADP, and a crystal complex structure of Hfq bound to ADP [Hfq and DsrA; strain not specified] (Mus musculus) PubMed

 8640.

Rrn3 crystal structure reveals a unique HEAT repeat fold and a surface serine patch [Rrn3] (Mus musculus) PubMed

 8641.

Leaf rust resistance and powdery mildew resistance co-locate with Sr2. [Sr2] (Mus musculus) PubMed

 8642.

These data show that the A domains of CTRP are critical for ookinete gliding motility and oocyst formation whilst, unexpectedly, its tandem thrombospondin type I repeat-like domains are fully redundant.[CTRP] (Mus musculus) PubMed

 8643.

A genetic and functional interaction between the innexin UNC-7 and the cation leak channel NCA in Caenorhabditis elegans neurons, is reported.[UNC-7, NCA] (Mus musculus) PubMed

 8644.

protein 7 modifies TGEV virulence, reducing virus pathology and increasing the period of virus shedding.[protein 7] (Mus musculus) PubMed

 8645.

findings indicate that the amino acid at position 100 of VP1 is important for EMCV in vivo infection, and its mutation alters the pathogenicity of viral infection in mice [VP1] (Mus musculus) PubMed

 8646.

S. Typhi trans-complemented with the functional sopD2 gene from S. Typhimurium (sopD2STM) reduced the invasion of human epithelial cell lines (sopD2). (Mus musculus) PubMed

 8647.

Hyperosmotic stress destroyed the structure of ocular surface epithelium, induced the decrease of conjunctival goblet cell density and MUC5AC expression, and led to decreased tear film stability. [MUC5AC] (Mus musculus) PubMed

 8648.

Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression. (Mus musculus) PubMed

 8649.

conformational coupling between the nucleotide-binding domain and the transmembrane domain in the Escherichia coli maltose transporter [maltose transporter] (Mus musculus) PubMed

 8650.

found that over-expression of the yGPN1 gene promotes sister chromatid separation during anaphase[GPN1] (Mus musculus) PubMed

 8651.

Sucrose non-fermenting1-related protein kinase 2 (SnRK2) plays a critical role in plant sugar signaling via phosphorylation.[SnRK2] (Mus musculus) PubMed

 8652.

Both Vibriocholerae FadR and Escherichia coli FadR bound the Vibrio cholerae plsB promoter region and binding was reversed upon addition of long-chain fatty acyl-CoA thioesters.[FadR & PlsB] (Mus musculus) PubMed

 8653.

Chlamydia protease-like activity factor (CPAF) targets chlamydial effectors secreted early during the establishment of the pathogen-containing vacuole [CPAF] (Mus musculus) PubMed

 8654.

Hemoglobin prevented expression of the agr quorum sensing system. (Mus musculus) PubMed

 8655.

findings show that the SaPI1-encoded protein gp6 is necessary for efficient formation of small capsids; suggests gp6 acts as an internal scaffolding protein in capsid size determination.[gp6 protein] (Mus musculus) PubMed

 8656.

Taken collectively, the results provide evidence that AspA is a biofilm-associated adhesin that may function in host colonization by Streptococcus pyogenes.[AspA] (Mus musculus) PubMed

 8657.

The SNP on exon 10 of the Wx gene, from C -> T, is a significant factor influencing gel consistency. [Waxy] (Mus musculus) PubMed

 8658.

conserved Mediator protein Ssn8 functions as a global regulator which negatively regulates diverse physiological and developmental processes and is required for virulence in C. neoformans [Ssn8] (Mus musculus) PubMed

 8659.

a high level of allelic diversity, 27 polymorphic nucleotides and 33 amino acid haplotypes of the Duffy Binding Protein II (DBPII) gene in 100 local Plasmodium vivax isolates collected from two hypoendemic areas (Mus musculus) PubMed

 8660.

Dimerization is required for and driven by receptor engagement of the Duffy binding protein (DBP). (Mus musculus) PubMed

 8661.

Using C-terminal fusion to Suc2-His4, the authors determined the orientation of full-length Arv1 in the endoplasmic reticulum membrane.[Avr1] (Mus musculus) PubMed

 8662.

Residue Phe-191 of B. subtilis UDG is critical for the interaction with phi29 p56 proteins. [p56] (Mus musculus) PubMed

 8663.

Identical domains of Vps23 are required for both Rim and ESCRT pathways, but the UEV domain was shown to bind the arrestin-like protein Rim8/PalF in the Rim pathway, whereas it binds Vps27 in the ESCRT pathway.[Vps23 & Rim8 & Vps27] (Mus musculus) PubMed

 8664.

The thk1 mutation defines a negative regulator that functions downstream of dek1 in the signaling system that controls aleurone specification and other aspects of endosperm development.[Thk1] (Mus musculus) PubMed

 8665.

Hrf1 conferred enhanced tolerance to drought stress on transgenic crops.[Hrf1] (Mus musculus) PubMed

 8666.

These results indicate that transcription of enterohemolysin (ehx) is positively regulated by Ler, GrlA, and LrhA, which all act as positive regulators for locus of enterocyte (LEE) expression.[ehx; LEE] (Mus musculus) PubMed

 8667.

This study compared the capacities of different espF alleles to inhibit bacterial phagocytosis by macrophages, translocation through an M-cell coculture system, and uptake by and translocation through cultured bovine epithelial cells.[EspF] (Mus musculus) PubMed

 8668.

The authors showed that AgrA is indispensable to agr P2 and P3 transcription, whereas SarA activates and SarR represses P2 transcription in the Agr locus. (Mus musculus) PubMed

 8669.

Gtf2 and its homologs GtfA and GtfB possess the conserved molecular chaperone activity that mediates protein glycosylation of bacterial adhesins [Gtf2, GtfA, GtfB] (Mus musculus) PubMed

 8670.

The conformational states of Escherichia coli Rep helicase undergoing ATP hydrolysis while bound to a partial-duplex DNA (pdDNA) were studied using single-molecule fluorescence resonance energy transfer.[Rep] (Mus musculus) PubMed

 8671.

This work defines two MntR-regulated new proteins, MntS and MntP, involved in manganese homeostasis and suggests mechanisms for their action.[MntS and MntP] (Mus musculus) PubMed

 8672.

This study characterized glycosylphosphatidylinositol-anchored micronemal antigen (GAMA) encoded by the PF08_0008 gene in Plasmodium falciparum.[GAMA] (Mus musculus) PubMed

 8673.

expression pattern of endogenous Apo-14 in zebrafish embryogenesis [Apo-14] (Mus musculus) PubMed

 8674.

gene and protein structures of the C. elegans filamin orthologs fln-1 and fln-2 [FLN-1][FLN-2] (Mus musculus) PubMed

 8675.

peel-1 encodes a novel four-pass transmembrane protein that is expressed in sperm and delivered to the embryo via specialized, sperm-specific vesicles. [peel-1] (Mus musculus) PubMed

 8676.

CyaY does not alter the relative ratio between [2Fe2S](2+) and [4Fe4S](2+) but directly affects enzymatic activity [CyaY][IscU] (Mus musculus) PubMed

 8677.

zinc regulates Zap1 activity post-translationally via three independent mechanisms [Zap1] (Mus musculus) PubMed

 8678.

pORF3 increases HNF4 phosphorylation through the ERK and Akt kinases [OFR3] (Mus musculus) PubMed

 8679.

a restricted terminal region of the chromosome is specifically dedicated to the last steps of chromosome segregation and to their coupling with cell division by FtsK [FtsK] (Mus musculus) PubMed

 8680.

O-acetylserine sulfhydrylase has predominantly entropy driven methionine binding is not mediated through classical hydrophobic binding, instead, may involve desolvation of the polar active site. (Mus musculus) PubMed

 8681.

levels of transcription of pfhrp2 and pfhrp3, and protein expression of PfHRP varied between different P. falciparum strains [pfhrp2][pfhrp3] (Mus musculus) PubMed

 8682.

Quantification of the in vivo Ni(2+)-NikR response of 11 direct NikR targets that encode functions related to nickel metabolism, four activated and seven repressed genes (NikR). (Mus musculus) PubMed

 8683.

[metallo-beta-lactamase IMP-1] Steady-state kinetic and spectroscopic studies suggest that metal binding to metal-free metallo-beta-lactamase (IMP-1) follows a positive-cooperative mode. (Mus musculus) PubMed

 8684.

The membrane topology of the cyanobacterial bicarbonate transporter, SbtA, was determined.[SbtA] (Mus musculus) PubMed

 8685.

tfoY is required for efficient transformation in V. fischeri, but is not functionally identical to tfoX. [tfoY] (Mus musculus) PubMed

 8686.

[uridine phosphorylase UPP] The reaction mechanism of uridine phosphorylase from T. cruzi is defined by steady-state and pre-steady-state kinetics, pH-rate profiles, kinetic isotope effects from uridine, and solvent deuterium isotope effects. (Mus musculus) PubMed

 8687.

Expression of auxin-related genes was affected in oni1 shoot.[Oni1] (Mus musculus) PubMed

 8688.

Evidence for a mechanism of intrachromosomal gene duplication where the GSH1 locus becomes polyploid preserving two intact copies of the essential gene upon sequential rounds of gene inactivation (GSH1). (Mus musculus) PubMed

 8689.

function in tick salivary gland may include inactivation of the salivation signal via sulfonation of dopamine or octopamine[SULT1 and Sult2] (Mus musculus) PubMed

 8690.

Lgt processing of lipoproteins is required for lipoprotein mediated innate immune activation.[Lgt] (Mus musculus) PubMed

 8691.

Modelling studies showed that the most functionality-lowering substitutions in OSC deeply alter the H-bond network involving the channel/constriction apparatus.[OSC] (Mus musculus) PubMed

 8692.

The sequence of nine al-2 mutant alleles, was determined and the carotenoid content in the corresponding strains, was analyzed.[al-2] (Mus musculus) PubMed

 8693.

A detailed biochemical analysis of NTPase/RNA helicase and 5'-RNA phosphatase activities of recombinant CHIKV-nsP2T protein was carried out.[nsP2] (Mus musculus) PubMed

 8694.

This study suggested that the constitutive expression of ramA locus regulate not only multidrug efflux pump and accessory genes but also genes involved in carbon metabolic pathways. (Mus musculus) PubMed

 8695.

global gene expression profile in stem bases of crl1 mutant and wild-type (WT) plants [CRL1] (Mus musculus) PubMed

 8696.

The synergistic increase is caused by the Ca(2+) influx from the extracellular medium via the Cch1-Yam8 complex.[Cch1, Yam8] (Mus musculus) PubMed

 8697.

Asp-208 is directly involved in proton motive force-driven protein export and that the cooperative interactions of FlhA with FlhB, FliH, FliI, and FliR drive the translocation of export substrate.[FlhA] (Mus musculus) PubMed

 8698.

The key role MtFTa1 plays in regulating flowering was demonstrated by the identification of fta1 mutants that flowered significantly later in all conditions examined.[MtFTa1] (Mus musculus) PubMed

 8699.

ROP18 phosphorylates and inactivates immunity-related GTPases , thereby protecting the parasite from killing.[Review][ROP18] (Mus musculus) PubMed

 8700.

These results suggest that Yfr017p functions as an inhibitor of Gdb1p, enhancing the ability of yeast cells to store glucose as glycogen.[Gdb1 & Yfr017] (Mus musculus) PubMed

 8701.

The influence of the lipid environment on p7 ion channel structure and function, was analyzed.[p7] (Mus musculus) PubMed

 8702.

The data support an orientation of the CitS and GltS monomers in the dimer with the N-termini close to the dimer interface.[GltS] (Mus musculus) PubMed

 8703.

The residue at the H5 helix position of the aromatic/arginine filter of both OsLsi1 and AtNIP5;1 plays a key role in the permeability to silicon and boron, but there is a relatively low selectivity for arsenite.[OsNIP2;1] (Mus musculus) PubMed

 8704.

Molecular-dynamics simulations of the bacterial multidrug ATP-binding cassette transporter Sav1866, is reported.[Sav1866] (Mus musculus) PubMed

 8705.

The search process is governed by the interaction between the virus and the LamB receptors, and by the spatial organization of the receptor network on the cell surface.[LamB] (Mus musculus) PubMed

 8706.

The effect of an inert small molecule osmolyte, trimethyl amine N-oxide (TMAO), upon the conformational equilibria of Escherichia coli adenylate kinase was studied using time-resolved fluorescence resonance energy transfer.[Adenylate kinase] (Mus musculus) PubMed

 8707.

data demonstrate that Puf2 is a key player in regulating sporozoite developmental control, and imply that transformation of salivary gland-resident sporozoites into liver stage-like parasites is regulated by a post-transcriptional mechanism [Puf2] (Mus musculus) PubMed

 8708.

The relationships among LuxO, LuxR, and the small regulatory RNA qrr4 in the model quorum-sensing bacterium Vibrio harveyi, were investigated.[LuxO, LuxR, Qrr4] (Mus musculus) PubMed

 8709.

TgNF3 protein is predominantly a nucleolar, chromatin-associated protein that binds specifically to T. gondii gene promoters in vivo, leading to a direct role in transcriptional regulation. [TgNF3] (Mus musculus) PubMed

 8710.

The authors used site-directed mutagenesis and azide rescue activity assays to show definitively that the catalytic base in Thermobifida fusca Cel48A is aspartic acid 225.[Cel48A] (Mus musculus) PubMed

 8711.

Data demonstrate that H. pylori HSP60/mAbs could modulate helicobacterial pathogenesis by increasing IL-8 and TNF-alpha production [Hsp60]. (Mus musculus) PubMed

 8712.

NorG positively regulated the transcription of global regulators mgrA, arlS, and sarZ. [NorG] (Mus musculus) PubMed

 8713.

A conjugation assay demonstrated cotransfer of tcrB (transferable copper resistance) and erm(B) genes between E. faecium and E. faecalis strains isolated from feces of piglets those were fed with copper supplemented diets. [tcrB] (Mus musculus) PubMed

 8714.

The level of AdpA directly affects expression of developmental genes. [AdpA ] (Mus musculus) PubMed

 8715.

holocytochrome c production by Saccharomyces cerevisiae HCCS [HCCS] (Mus musculus) PubMed

 8716.

Transient-expression assays revealed the colocalization of the plant histone H3 and nuclear shuttle protein (NSP) in the nucleus and nucleolus and of histone H3 and movement proteins in the cell periphery and plasmodesmata.[NSP] (Mus musculus) PubMed

 8717.

The authors demonstrate that the RNA-binding activity of NP is necessary for stabilization of cRNA, whereas, surprisingly, homo-oligomerization of NP is not essential.[NP] (Mus musculus) PubMed

 8718.

Transfection of the SVGA astrocyte cell line with a plasmid encoding gp120 resulted in a time-dependent increase in expression levels of CCL5 in terms of mRNA and protein by 24.6 +/- 2.67- and 35.2 +/- 6.1-fold, respectively. [gp120] (Mus musculus) PubMed

 8719.

ShanDong-Satellite RNAs reduced the accumulation of the 2b protein and its coding RNA4A and attenuated the yellowing caused by ShanDong strain, Cucumber mosaic virus (SD-CMV)infection.[2b protein] (Mus musculus) PubMed

 8720.

Expression of DR0171 increased in response to gamma radiation. Inactivation of dr0171 increases the susceptibility of D. radiodurans cells to DNA-damaging agents. [DR0171] (Mus musculus) PubMed

 8721.

Cyclic di-GMP and quorum sensing control the expression of vpsT and aphA. [vpsT] (Mus musculus) PubMed

 8722.

A conjugation assay demonstrated cotransfer of tcrB (transferable copper resistance) and erm(B) genes between E. faecium and E. faecalis strains isolated from feces of piglets those were fed with copper supplemented diets. [tcrB] (Mus musculus) PubMed

 8723.

OsSFR6 can act as a functional orthologue of AtSFR6 in the acquisition of freezing tolerance in Arabidopsis. [SFR6] (Mus musculus) PubMed

 8724.

Rpa43 directly bind Spt5, an RNAPI elongation factor also acting in RNAPII-dependent transcription, and may also interact with the nucleosomal chaperone Spt6 [Rpa43] (Mus musculus) PubMed

 8725.

H2BK123ub is removed by the deubiquitinases Ubp8 and Ubp10, but their genomic target regions remain to be determined [Ubp8, Ubp10, H2BK123; no strain indicated] (Mus musculus) PubMed

 8726.

mechanistically similar functions of H2B ubiquitylation (nucleosome assembly) elicit different functional outcomes on genes depending on its positional context in promoters (repressive) versus transcribed regions (activating) [strain not found; H2B] (Mus musculus) PubMed

 8727.

Parasites in which TbbetaHBDH (beta-hydroxybutyrate dehydrogenase) is depleted exhibit slowed growth, indicating an important role for this enzyme in vivo.[beta-hydroxybutyrate dehydrogenase] (Mus musculus) PubMed

 8728.

CYP71Z6 & 7 appear to have evolved distinct roles in rice diterpenoid metabolism [CYP71Z6][CYP71Z7] (Mus musculus) PubMed

 8729.

transcription of pacC is modulated in response to alternative RNA splicing of the palB gene [pacC][palB] (Mus musculus) PubMed

 8730.

Rpa43 directly bind Spt5, an RNAPI elongation factor also acting in RNAPII-dependent transcription, and may also interact with the nucleosomal chaperone Spt6 [Rpa43] (Mus musculus) PubMed

 8731.

AgsA fibrils may represent a distinctive type of structural and functional form of small heat shock protein from spherical oligomers [AgsA] (Mus musculus) PubMed

 8732.

CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication [p97] (Mus musculus) PubMed

 8733.

UreB facilitates the interaction of urease with accessory proteins during metallocenter assembly, with the N-terminal hinge and tether region being specifically required for this process. [UreB] (Mus musculus) PubMed

 8734.

structural differences between SrtA and SrtC1 [SrtA][SrtC1] (Mus musculus) PubMed

 8735.

The study used high-resolution optical tweezers to characterize the folding and unfolding reactions of a single GCN4 coiled coil domain and their dependence on the pulling direction. [GCN4] (Mus musculus) PubMed

 8736.

the existence of a relationship between tubulins and P450 cytochromes during A. gambiae immune response to P. berghei invasion [cytochrome P450 reductase] (Mus musculus) PubMed

 8737.

analysis of substrate specificity of TbSLS1, an inositol phosphorylceramide (IPC) synthase, and TbSLS4, a bifunctional sphingomyelin (SM)/ethanolamine phosphorylceramide (EPC) synthase [TbSLS1, TbSLS4] (Mus musculus) PubMed

 8738.

ATPase p529 of Acidianus two-tailed virus associates with the Sulfolobus solute binding protein Sso1273. [p529] (Mus musculus) PubMed

 8739.

[IscU] IscU is conformationally flexible and may allow for formation of iron-sulfur (FeS) complexes having different coordination patterns and binding stabilities as evidenced by differences in ability to transfer iron-sulfur clusters to apo-ferredoxin. (Mus musculus) PubMed

 8740.

A T. brucei GNA1 conditional null mutant was shown to be unable to sustain growth in vitro under nonpermissive conditions, demonstrating that there are no metabolic or nutritional routes to UDP-GlcNAc other than via GlcNAc-6-phosphate. [GNA1] (Mus musculus) PubMed

 8741.

The effects of the polymorphisms of the follicle-stimulating hormone receptor (FSHR) gene on egg production in a Beijing You chicken population divergently selected for egg number, egg weight, and BW across 3 generations are reported.[FSHR] (Mus musculus) PubMed

 8742.

[U1 snRNP ribozyme] In contrast to most large and small ribozymes, the HDV ribozyme modeled in this review facilitates nucleophile RNA deprotonation and stabilizes conformation of the magnesium-dependent active site for in-line nucleophile attack. (Mus musculus) PubMed

 8743.

This study examined the frequency of Plasmodium falciparum chloroquine transporter (pfcrt) haplotypes in Sri Lanka in 1996-1998 and 2004-2006 using a high-resolution melting assay.[pfcrt] (Mus musculus) PubMed

 8744.

These results clarify recombination-mediated routes of cagA evolution and provide a solid basis for a deeper understanding of its function in pathogenesis.[cagA] (Mus musculus) PubMed

 8745.

This study describes the conformational changes of SecB upon binding of all-Ala-bovine pancreatic trypsin inhibitor to spin-labeled single cysteine mutants of SecB. [SecB] (Mus musculus) PubMed

 8746.

Among the identified HdeA client proteins, the periplasmic chaperones DegP and SurA were initially found to be protected by HdeA at a low pH, but they subsequently facilitated the HdeA-mediated acid recovery of other client proteins.[HdeA] (Mus musculus) PubMed

 8747.

FRQ-bound CK1a progressively phosphorylates the positively charged N-terminal domain of FRQ at up to 46 nonconsensus sites, triggering a conformational change [FRQ] (Mus musculus) PubMed

 8748.

we identified a protein homologous to a mammalian solute carrier family 4 (SLC4) bicarbonate transporter that we show is involved in valproic acid uptake. [SLC4] (Mus musculus) PubMed

 8749.

Ypd1 is required for the viability of Cryptococcus neoformans via the Hog1 mitogen-activated protein kinase (MAPK) pathway but plays multiple cellular roles in both a Hog1-dependent and -independent manner. [Ypd1] (Mus musculus) PubMed

 8750.

Suggest ammonia excretion via Rhcg1 in larval zebrafish gills is linked to sodium uptake via NHE3b. (Mus musculus) PubMed

 8751.

Comparison of the native enzyme responses with those of a mutant allowed identification of the elementary steps that makes the mutant type more efficient than the wild type. [quinoprotein glucose dehydrogenase] (Mus musculus) PubMed

 8752.

Our studies identify the role of AidB in alkylating agent exposed cells and suggest a new cellular strategy in which a subset of the genome is preferentially protected from damage by alkylating agents. (Mus musculus) PubMed

 8753.

Intrinsic multiple functions of gene product 5 are shown to be served in turn regulated by gradual change of interdomain interactions, which enables the initial infection process with single protein trimer by continuous screw motion. [gene product 5] (Mus musculus) PubMed

 8754.

Host temperature adaptation is accompanied by transient induction of the endoplasmic reticulum stress response and Ccr4-dependent posttranscriptional gene regulation contributes to resolution of ER stress during host temperature adaptation. [CCR4] (Mus musculus) PubMed

 8755.

SDF-1 apparently acts through the adenylyl cyclase ACG to activate the cyclic AMP-dependent protein kinase A and trigger the production of more SDF-1. [SDF-1] (Mus musculus) PubMed

 8756.

Putrescine is required for the expression of eif-5a. [eif-5a] (Mus musculus) PubMed

 8757.

Our data suggest that Hsl7 may regulate cell cycle progression, while both Smu1 and Cla4 appear to be involved in the filamentous response in U. maydis. [Hsl7] (Mus musculus) PubMed

 8758.

A novel phenylacetic acid-induced CoA-ligase encoding gene, designated as phlC, has been cloned from penicillin-producing fungus Penicillium chrysogenum. [phlC] (Mus musculus) PubMed

 8759.

Exposure to arsenic downregulates EAAT1/GLAST activity and expression by a mechanism that involves several protein kinases, particularly p38 mitogen-activated protein kinase. (Mus musculus) PubMed

 8760.

Shq1p operates as a Cbf5p chaperone during RNP assembly by acting as an RNA placeholder, thereby preventing Cbf5p from nonspecific RNA binding before association with an H/ACA RNA and the other core RNP proteins [strain not noted; SHQ1] (Mus musculus) PubMed

 8761.

The study reports comparison of the cleavage efficiencies of all known hepatitis C virus NS3-4A protease cleavage sequences in a cell-based system. [NS3-4A protease] (Mus musculus) PubMed

 8762.

Our results indicate that TbISWI is a versatile chromatin remodeler that regulates transcription at multiple Pol I loci and is particularly abundant at many Pol II transcription boundaries in T. brucei. [TbISWI] (Mus musculus) PubMed

 8763.

Disclosed is the critical role of a specialized glutathione S-transferase (GST), GliG, which mediates carbon-sulfur bond formation in gliotoxin biosynthesis. [glutathione S-transferase] (Mus musculus) PubMed

 8764.

An insertional mutation into the Ler linker region diminished oligomerization activity.[Ler] (Mus musculus) PubMed

 8765.

The crystal structure of PDH from Streptococcus mutans in a complex with NAD(+) shows that the enzyme exists as a homo-dimer.[PDH] (Mus musculus) PubMed

 8766.

The two consecutive glutamates in the beta4/alpha4 loop of T. maritima CheB that is absent in T. maritima CheY and in E. coli/S. typhimurium CheB may be one factor contributing to the low CheA affinity.[CheA, CheB] (Mus musculus) PubMed

 8767.

Cationic lipids enhanced the assembly of FtsZ in association with an increase in the GTPase activity of FtsZ.[FtsZ] (Mus musculus) PubMed

 8768.

The two consecutive glutamates in the beta4/alpha4 loop of T. maritima CheB that is absent in T. maritima CheY and in E. coli/S. typhimurium CheB may be one factor contributing to the low CheA affinity.[CheA, CheB] (Mus musculus) PubMed

 8769.

The structure of PfCS along with cofactor FMN was predicted by homology modeling.[CS] (Mus musculus) PubMed

 8770.

This study demonstrates that CAF1 of the CCR4-Not complex is a significant gene regulatory mechanism needed for Plasmodium development within the human host [CCR4-associated factor 1] (Mus musculus) PubMed

 8771.

we identified the ligand binding surface and the critical residues responsible for ligand binding of HtrA PDZ domain by chemical shift perturbation and site-directed mutagenesis. [HtrA] (Mus musculus) PubMed

 8772.

These data reveal that the Staphylococcus epidermidis SarX protein regulates the transcriptional activity of the agr and ica loci and controls the biofilm phenotype, primarily by regulating icaADBC transcription and PIA production.[SarX] (Mus musculus) PubMed

 8773.

A gene encoding aminolevulinate synthase (ALA-S) in yeast (Saccharomyces cerevisiae YHem1) was introduced into the genome of tobacco (Nicoliana tabacum) under the control of Arabidopsis thaliana HemA1 gene promoter (AtHemA1 P).[YHem1] (Mus musculus) PubMed

 8774.

These findings suggested a complicated transcriptional regulation of OsUgp2.[OsUgp2] (Mus musculus) PubMed

 8775.

Data suggest that RctB has at least two DNA binding domains-one for binding to oriCII and initiating replication and the other for binding to rctA and thereby inhibiting RctB's ability to initiate replication: [rctA & rctB] (Mus musculus) PubMed

 8776.

Pep plays a critical role in the pathogenesis. [Pep] (Mus musculus) PubMed

 8777.

LAPTc is a 330-kDa homohexameric metalloaminopeptidase expressed by all T. cruzi forms and mediates the major parasite leucyl aminopeptidolytic activity. [LAPTc] (Mus musculus) PubMed

 8778.

Overall, these results indicate that the muramidase activity of EtgA is not critical but makes a significant contribution to the efficiency of the type III secretion process.[EtgA] (Mus musculus) PubMed

 8779.

Characterization of the structure and function of Escherichia coli DegQ as a representative of the DegQ-like proteases of bacterial HtrA family proteins. [DegQ] (Mus musculus) PubMed

 8780.

structural models for PfMDR1 in different predicted conformations [PfMDR1] (Mus musculus) PubMed

 8781.

modification of respiratory chain proteins and stress response proteins suggests the occurrence of a mild oxidative stress in anxC4 disruptant strain[annexin C4] (Mus musculus) PubMed

 8782.

The authors have identified the acetyltransferase p300 as an additional target of Escherichia coli type III secreted protease NleC.[NleC] (Mus musculus) PubMed

 8783.

All Asp-hemolysin mutant strains showed no attenuation in virulence in a mouse infection model for invasive pulmonary aspergillosis.[Asp-hemolysin] (Mus musculus) PubMed

 8784.

IdiC is loosely attached to the thylakoid and to the cytoplasmic membranes and that its expression is enhanced during conditions of iron starvation and during the late growth phase.[IdiC] (Mus musculus) PubMed

 8785.

Antigenic sites A and D in the S protein completely inhibit viral infection. [Spike protein, S protein] (Mus musculus) PubMed

 8786.

Rev protein of Human Immunodeficiency Virus type 1 (HIV-1) inhibits nuclear import and mediates nuclear export of the HIV-1 integrase (IN) protein [integrase] (Mus musculus) PubMed

 8787.

The crystal structure of endonuclease I has been solved both as free protein and in complex with a DNA junction, showing that the protein, as well as the junction, becomes distorted on binding. [T7 endonuclease I] (Mus musculus) PubMed

 8788.

The interactions of C and histones add an interesting new role for the presence of C in the nucleus during Dengue virus infection.[Capsid protein] (Mus musculus) PubMed

 8789.

P. falciparumRh5 interacting protein forms a complex with PfRh5 in merozoites. PfRipr protein localises to the apical end of the merozoites in micronemes whilst PfRh5 is contained within rhoptries and both are released during invasion[PfRipr] (Mus musculus) PubMed

 8790.

By means of the energy decomposition method, the study identifies the residues that have the biggest influence on catalysis. [trans-sialidase] (Mus musculus) PubMed

 8791.

Apical complex lysine (K) methyltransferase depletion greatly inhibits activation of motility, compromises Toxoplasma gondii invasion and egress, and thus severely impairs the lytic cycle[AKMT] (Mus musculus) PubMed

 8792.

We expressed and purified a 13.4 kDa fragment of Engrailed 2, which comprises a 54-residue N-terminal extension in addition to the homeodomain region. Almost all backbone and side-chain resonances have been assigned. (Mus musculus) PubMed

 8793.

Here we present the near complete assignment of Schistosoma mansoni IPSE/alpha-1 variant, IPSEDeltaNLS, which comprises the core domain of the protein. (Mus musculus) PubMed

 8794.

The study reports the generation and biophysical characterization of deflavinated AidB and of an AidB mutant that has greatly reduced affinity for flavin adenine dinucleotide. [AidB] (Mus musculus) PubMed

 8795.

The W56H variant showed an increased stability of the complex against autoxidation and a slower rate of O(2) activation. [nitric oxide synthase] (Mus musculus) PubMed

 8796.

This study uses a combination of limited proteolysis, mass spectrometry, and N-terminal sequencing to precisely define the interaction region of Smc5 with Mms21. [Smc5, Mms21] (Mus musculus) PubMed

 8797.

This study reports the structure of the 2-aminopurine-dCTP base pair formed within the polymerase active site of the RB69 Y567A-DNA polymerase. [DNA polymerase] (Mus musculus) PubMed

 8798.

MltE and MltC regulated cell wall turnover and biofilm formation. [MltE] (Mus musculus) PubMed

 8799.

CipB does not seem to participate in membrane depolarization to assist passage of DNA. [CipB] (Mus musculus) PubMed

 8800.

MtrC protein trafficking to the outer membrane and its subsequent degradation are tightly regulated, which is consistent with cellular processing pathways that target MtrC to extracellular structures. (MtrC metal reductase) (Mus musculus) PubMed

 8801.

HapR, RpoS, and c-di-GMP regulated hapA expression. [HapR,HapA] (Mus musculus) PubMed

 8802.

OsGDI3 functions as a negative regulator of OsMAPK2 through modulating its kinase activity.[OsGDI3][OsMAPK2] (Mus musculus) PubMed

 8803.

KRT31, KRT33A, KRT33B, KRT34, KRT36, KRT38-39, KRT81, KRT83 and KRT86-87 are expressed only in the fibre cortex. (Keratin 87) (Mus musculus) PubMed

 8804.

Genetic interaction between Caenorhabditis elegans teneurin ten-1 and prolyl 4-hydroxylase phy-1 and their function in collagen IV-mediated basement membrane integrity during late elongation of the embryo. [phy-1] (Mus musculus) PubMed

 8805.

These findings suggest that naturally acquired immunity against Pfs48/45 and Pfs230 is a function of recent exposure rather than of cumulative exposure to gametocytes.[Pfs48-45; Pfs230] (Mus musculus) PubMed

 8806.

Both amino- (1-226) and carboxyl-terminal (196-403) parts of the LeIF protein were shown to induce significant levels of the three cytokines analysed.[LeIF] (Mus musculus) PubMed

 8807.

Glycine max and Medicago extracellular fluids were each shown to possess an endoproteolytic activity that recognizes and cleaves at border sequences in a synthetic 31 amino acid CLE36.[CLE36] (Mus musculus) PubMed

 8808.

A transcriptional and translational analysis of S. meliloti hfq expression by means of lacZ reporter fusions strongly suggests that the S. meliloti Hfq protein autocontrols its expression at the translational level (hfq). (Mus musculus) PubMed

 8809.

POSTN is involved in conceptus elongation during early pregnancy.[Periostin; Ovis aries] (Mus musculus) PubMed

 8810.

This study identify DCAR-1 as the first seven-transmembrane receptor required for avoidance of a water-soluble repellent, DHCA, in C. elegans. (Mus musculus) PubMed

 8811.

(cagA) An inhibitory effect of H. pylori results from activation of the transcription factor heat shock factor(HSF)-1 by H. pylori virulence factor CagA and by host signaling molecules ERK1/2 and JNK kinases [CagA] (Mus musculus) PubMed

 8812.

S. mutans lipoprotein PpiA contributes to suppression of MARCO-mediated phagocytosis of this bacterium by macrophages. [PpiA] (Mus musculus) PubMed

 8813.

Epstein - Barr virus Latent Membrane Protein 1 suppresses reporter activity through modulation of promyelocytic leukemia protein-nuclear bodies. (Mus musculus) PubMed

 8814.

The structural and mutagenesis analyses reported here establish ChuZ and ChuZ homologs as a new bacterial heme oxygenase family apart from the canonical and IsdG/I families.[ChuZ] (Mus musculus) PubMed

 8815.

Localization of the beta giardin protein between assemblages A and B are different but localization of alpha-1 giardin in strains from assemblages A and B are the same. (Mus musculus) PubMed

 8816.

Increased muscle activity after low-dose injections of botulinum toxin in mice does not influence the efficacy of the toxin in normal mouse muscles. (Mus musculus) PubMed

 8817.

E. coli TopA may be modulated by iron and zinc binding in vivo [TopA] (Mus musculus) PubMed

 8818.

OsGMST1 may play a direct or an indirect role in tolerance to salt stress in rice. (Mus musculus) PubMed

 8819.

Pst1 is the main phosphate transporter. [Pst1] (Mus musculus) PubMed

 8820.

Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH [IsdH] (Mus musculus) PubMed

 8821.

analysis of GlgE from Streptomyces and Mycobacterium tuberculosis [GlgE] (Mus musculus) PubMed

 8822.

Dd-PIAS controls the developmental speed and duration of slug migration. Dd-PIAS does not affect Dd-STATa nuclear localization. [STATa; PIAS] (Mus musculus) PubMed

 8823.

HSFd protein binds to heat shock elements and may activate mRNA expression of Hsp70a and Samui genes upon exposure of diapause eggs to 5 degrees C. [HSP70a] (Mus musculus) PubMed

 8824.

The direct binding of the PmrA regulator to a specific promoter site induces the expression of the wzz(fepE) gene (PmrA and wzzfepE). (Mus musculus) PubMed

 8825.

The results suggested that Paracoccidioides brasiliensis gp43 binds to human TLR2, TLR4, and mannose receptors, with TLR2 and mannose receptors having the strongest effect.[gp43] (Mus musculus) PubMed

 8826.

Rrd1 is a novel transcription elongation factor that fine-tunes the transcriptional stress response of RNAPII.[Rrd1] (Mus musculus) PubMed

 8827.

Viral capture of an ankyrin-like domain in Epstein-Barr virus BZLF1 ZEBRA protein provides a mechanism for binding to proteins in the NF-kappaB and p53 transcription factor families. (Mus musculus) PubMed

 8828.

PcaQ regulates the expression of the S. meliloti smb20568-smb20787-smb20786-smb20785-smb20784 gene cluster, which is predicted to encode an ABC transport system (PcaQ). (Mus musculus) PubMed

 8829.

mice immunized intranasally with the FlaB-PspA fusion protein were the most protected from a lethal challenge with live S. pneumoniae [FlaB] (Mus musculus) PubMed

 8830.

Structural and functional analysis of the tandem beta-zipper interaction of a Streptococcal protein with human fibronectin [SfbI-5] (Mus musculus) PubMed

 8831.

Our data showed that a prime-boost immunization using heterologous MPR 649-684-displaying immunogens, i.e., F1-V MPR 649-684 and CTB MPR 649-684, may provide a solution to overcome the poor humoral immunogenicity of MPR 649-684. [gp41] (Mus musculus) PubMed

 8832.

H-NS silencing of hilA is antagonized by integration host factor (H-NS, hilA and integration host factor). (Mus musculus) PubMed

 8833.

The functional role of ghrelin and peripheral GHS-R1a for the regulation of gastrointestinal motility is weak in the guinea-pig. (Mus musculus) PubMed

 8834.

Nasal administration of Flt3 ligand cDNA with Phosphorylcholine may contribute to the development of nasal vaccination for prevention of S. pneumoniae infection. [Flt3] (Mus musculus) PubMed

 8835.

results show segment 7 and 8 mRNAs of A/Brevig Mission/1918/1 (H1N1) were inefficiently spliced; this resulted in production of higher levels of NS1 protein, which could potentially contribute to its pathogenic properties [NS1] (Mus musculus) PubMed

 8836.

Data present the crystal structures of Schizosaccharomyces pombe aprataxin Hnt3 and dsDNA-AMP reveal how Hnt3 recognizes and processes 5'-adenylated DNA in a structure-specific manner. (Mus musculus) PubMed

 8837.

TbSA C2 utilized alpha2-3 sialyllactose as a donor, and produced an alpha2-3-sialylated product, suggesting that it is an alpha2-3 trans-sialidase; TbSA C2 plays a role in the sialic acid modification of the trypanosome cell surface. [TbSAC2] (Mus musculus) PubMed

 8838.

The substrate specificity of the Aro8 encoded aminotransferase was investigated; The enzyme should be classified as an alpha-aminoadipate aminotransferase. [alpha-aminoadipate aminotransferase] (Mus musculus) PubMed

 8839.

This study reports the cloning and characterization of a putative type III polyketide synthase from Aspergillusniger, AnPKS. [AnPKS] (Mus musculus) PubMed

 8840.

the gating mechanism of a type II ABC importer, the BtuCD-F vitamin B(12) importer from Escherichia coli [BtuCD-F] (Mus musculus) PubMed

 8841.

The chaperonin TRiC was shown to assist an ATP-dependent refolding of recombinant forms of sperm-specific glyceraldehyde-3-phosphate dehydrogenase. [chaperonin TRiC] (Mus musculus) PubMed

 8842.

The autophagic process was blocked in the ATG5 deletion mutant. [ATG5] (Mus musculus) PubMed

 8843.

Identification of the keratin-associated protein KAP1-2 gene (KRTAP1-2). PCR-SSCP analysis of KRTAP1-2 revealed nine unique banding patterns representing nine different DNA sequences. (KRTAP1-2). (Mus musculus) PubMed

 8844.

the identification and dynamics characterization of a tvMyb2 fragment comprising amino acid residues 40-156 (tvMyb240-156) as the minimum structural unit that retains near full binding affinity with the ap65-1 gene promoter DNA (Myb2). (Mus musculus) PubMed

 8845.

two major R genes, designated Pi47 and Pi48, were located between RM206 and RM224 on chromosome 11, and between RM5364 and RM7102 on chromosome 12, respectively [Pi47;Pi48] (Mus musculus) PubMed

 8846.

The authors show that Qs, an RNA from the 5' end of the prgQ operon, represses expression of PrgX by targeting prgX mRNA for cleavage by RNase III.[RNase III] (Mus musculus) PubMed

 8847.

Fe-S clusters synthesis is regulated by the leucine biosynthetic pathway involving Leu1p and Aco1p [Atm1p][Aco1p][Leu1p] (Mus musculus) PubMed

 8848.

Cooperativity of cAMP binding is generally correlated to the global dynamics of the protein and DNA binding affinity. [cAMP binding receptor protein] (Mus musculus) PubMed

 8849.

study determined whether ongoing expression of HPV16 or HPV18 oncogenes is required for the proliferation of primary human cervical carcinoma cells; data suggest that E6 and E7 dependence is an inherent property of human cervical cancer cells [E6,E7] (Mus musculus) PubMed

 8850.

Our results support a role for RIC8 in regulating GNA-1 and GNA-3 in Neurospora. (Mus musculus) PubMed

 8851.

The L98H induced relocation of tyrosine 121 and tyrosine 107 seems to be related to the multi-azole-resistance phenotype, without affecting the biological activity of the CYP51A protein.[CYP51A] (Mus musculus) PubMed

 8852.

allosterism between the nucleotide and DNA binding sites in MutS can occur via ligand-induced changes in motion, i.e., dynamical allosterism [MutS] (Mus musculus) PubMed

 8853.

Sgs4 and Sgs5 are produced exclusively in female salivary glands [Sgs4][Sgs5] (Mus musculus) PubMed

 8854.

relative ligand binding free energy by mutating tryptophans in the Trichoderma reesei family 6 cellulase (Cel6A) to alanine [Cel6A] (Mus musculus) PubMed

 8855.

[differentiation inducing factor 1; DIF-1]Inhibits Wnt/beta-catenin signaling pathway by suppressing transcription factor 7-like 2 expression via reduced early growth response (Egr)-1-dependent transcriptional activity in human colon cancer cells (Mus musculus) PubMed

 8856.

Both Isa1 and Isa2 are indispensable for growth, as they are required for the assembly of Fe-S clusters in mitochondrial aconitase, fumarase and succinate dehydrogenase.[Isa1 and Isa2] (Mus musculus) PubMed

 8857.

The present study establishes TNC as a functional plasma membrane nickel transporter necessary for physiological acquisition of nickel in the multicellular fungi Neurospora crassa.[TNC] (Mus musculus) PubMed

 8858.

Expression of the metalloreductase FreB was found to be transcriptionally repressed by iron via SreA, a repressor of iron acquisition during iron sufficiency, indicating a role in iron metabolism.[FreB] (Mus musculus) PubMed

 8859.

PhoB binding to distinct Pho boxes enables the precise control of phoBR expression. [PhoB, PhoR] (Mus musculus) PubMed

 8860.

Srr1, Srr2 and PilA contribute to adherence to vaginal epithelial cells. [Srr1, Srr2, PilA] (Mus musculus) PubMed

 8861.

Bap1 was concentrated at the biofilm-surface interface and stabilized the association of the multilayer biofilm with the surface. [BAP1] (Mus musculus) PubMed

 8862.

In this study, we have identified a new posterior body contraction calcium-binding protein, PBO-1/CHP, that regulates at least two intestinal sodium-proton exchangers in C. elegans [pbo-1] (Mus musculus) PubMed

 8863.

NanR, CRP, and N-acetylmannosamine 6-phosphate cooperate for precise adjustment of the expression level of the V. vulnificus nan cluster (Mus musculus) PubMed

 8864.

the 1-600-amino acid domain of DPB11 is both required and sufficient for full replication function of Dpb11 but that this domain is defective for activation of the principal checkpoint kinase Mec1 in vitro and in vivo.[Dpb11] (Mus musculus) PubMed

 8865.

The authors concluded that the central regulatory unit composed of AdpA and BldA plays important roles in the initiation of morphological differentiation and secondary metabolism triggered by A-factor.[BldA] (Mus musculus) PubMed

 8866.

Transcription factor NusA modulates the transcriptional pausing of RNA polymerase in Escherichia coli. (Mus musculus) PubMed

 8867.

These data suggest that rak1 is a regulator of rop1 expression with additional roles after cell fusion.[Rak1] (Mus musculus) PubMed

 8868.

Secretion of SmHMGB1 is regulated by phosphorylation.[HMGB1] (Mus musculus) PubMed

 8869.

The study examines SSB binding to shorter oligodeoxynucleotides ((dX)35) to probe whether this effect requires binding of one or two (dX)35 molecules per SSB tetramer. [SSB] (Mus musculus) PubMed

 8870.

These results document a distinct transcriptional profile invoked by the HIV-1/V3 epitope.[gp120] (Mus musculus) PubMed

 8871.

This study describes two novel regulators, GalX and GalR, that control d-galactose utilization in Aspergillus nidulans.[GalX and GalR] (Mus musculus) PubMed

 8872.

The data presented here show that glycosylphosphatidylinositol-linked alkaline phosphatase (GPI-ALP) from Aedes aegypti has high-affinity binding to Bacillus thuringiensis Cry4Ba toxin even in the absence of protein glycosylation.[GPI-ALP] (Mus musculus) PubMed

 8873.

The beta-agarase AgaA(CN41) belongs to the GH50 (glycoside hydrolase 50) family but yields neoagarotetraose as the end product.[AgaA] (Mus musculus) PubMed

 8874.

A GFP::MtRopGEF2 fusion protein localizes in the apex of emerging and actively growing root hairs. The amino terminus of MtRopGEF2 regulates its ability to interact with MtRops in yeast, and regulates its biological activity in vivo.[RopGEF] (Mus musculus) PubMed

 8875.

Medicago truncatula Vapyrin (VPY) gene is required for rhizobial colonization and nodulation. (Mus musculus) PubMed

 8876.

findings show that pcsB is not essential for cell survival but is essential for proper cell division;data suggest that LysM domain proteins partially compensate for the lack of PcsB function and allow the survival and slow growth of the pneumococcus (Mus musculus) PubMed

 8877.

results indicate that MNX1 and MNX2 code for flavoprotein monooxygenases catalysing the first steps in the 3-oxoadipate and gentisate pathways, respectively ( 4-hydroxybenzoate 1-hydroxylase and 3-hydroxybenzoate 6-hydroxylase)[MNX1, MNX2] (Mus musculus) PubMed

 8878.

Streptococcus gordonii FSS2, an infective endocarditis isolate, expresses a dipeptidyl-carboxypeptidase with activity homologous to angiotensin-converting enzyme [challisin] (Mus musculus) PubMed

 8879.

conformational changes in the protein's ATPase site in solution (Mus musculus) PubMed

 8880.

Two internal NDH2 isoforms are both required for optimal tachyzoite growth. [NDH2] (Mus musculus) PubMed

 8881.

PKA-dependent regulation of Cdc25 RasGEF localization [Tpk1][Cdc25] (Mus musculus) PubMed

 8882.

subunit coordination may be general to many ring-shaped helicases and reveals a potential mechanism for regulation of DNA unwinding during replication [gene product 4] (Mus musculus) PubMed

 8883.

The authors suggest that the continued engagement of the receptor binding protein is essential to F protein function until the onset of membrane merger.[HN] (Mus musculus) PubMed

 8884.

The lymphocytic choriomeningitis virus nucleoprotein domain that interacted with Z overlapped with a previously documented C-terminal domain that counteracts the host type I interferon (IFN) response.[Z] (Mus musculus) PubMed

 8885.

Overall, the results presented here point toward an important role for PCBP1 and PCBP2 in regulating porcine reproductive and respiratory syndrome virus RNA synthesis via binding to viral nonstructural protein 1beta.[nonstructural protein 1beta] (Mus musculus) PubMed

 8886.

ScbR2 negatively controls the biosynthesis of gamma-butyrolactone by directly repressing the transcription of scbA. [ScbR2] (Mus musculus) PubMed

 8887.

GEST mediates malaria transmission to both mosquito and vertebrate host. {GEST] (Mus musculus) PubMed

 8888.

Wzd and Wze are spatial regulators of capsular polysaccharide synthesis.[Wzd, Wze] (Mus musculus) PubMed

 8889.

SbP5CS1 and SbP5CS2 are stress inducible genes but might play non-redundant roles in plant development. [SbP5CS1; SbP5CS2] (Mus musculus) PubMed

 8890.

RMR1 functions as a sorting receptor in transporting vicilin-like storage proteins. [RMR1] (Mus musculus) PubMed

 8891.

function of two hydrophobic domains in the C-terminal region of the Tob37 protein and Tob38 protein [Tob37][Tob38] (Mus musculus) PubMed

 8892.

comprehensive information on the CRE-1 regulon in N. crassa [CRE-1] (Mus musculus) PubMed

 8893.

TRIM79 restricts tick-borne encephalitis virus replication by degradation the NS5 protein, an RNA-dependent RNA polymerase essential for virus replication. [NS5] (Mus musculus) PubMed

 8894.

The authors provide evidence that the Kluyveromyces lactis KlPDR1 gene is under positive autoregulation by KlPdr1p, which plays a role in the activation of the main multidrug resistance transporter gene KlPDR5.[KlPDR1] (Mus musculus) PubMed

 8895.

the residual resection observed in Exo1-mutant cells is dependent on Mre11, and both exonuclease activities are required for efficient DNA double-strand break repair [Exo1 & Mre11] (Mus musculus) PubMed

 8896.

identification of an iron-dependent sulphide transfer reaction from a conserved cysteine residue of the protein to a reaction intermediate and the demonstration that THI4p is a suicide enzyme undergoing only a single turnover [THI4] (Mus musculus) PubMed

 8897.

IcmF mutant has decreased adherence to and invasion of epithelial cells and decreased intra-macrophage survival. [IcmF] (Mus musculus) PubMed

 8898.

HNS control the integrase IntI1 and integron promoters expression. [IntI1] (Mus musculus) PubMed

 8899.

PKB/Akt expression decreased in adrenocortical cells induced by cadmium chloride. [PKB] (Mus musculus) PubMed

 8900.

OsKNOLLE plays a crucial role in responses to abiotic stresses. [KNOLLE] (Mus musculus) PubMed

 8901.

The first negative regulatory histone methylation is observed in budding yeast and indicates that histone H4 lysine 20 is evolutionarily conserved from simple to complex eukaryotes. (Mus musculus) PubMed

 8902.

an additional subunit of the Gid complex containing a degenerated RING finger, Gid9/Fyv10 [Gid9] (Mus musculus) PubMed

 8903.

Rvb2 physically associates with telomerase/Est2 in vivo [Rvb2][Est2] (Mus musculus) PubMed

 8904.

the inhibitory effect of alpha(1)-antitrypsin on the catalytic activity of trypsin [alpha(1)-antitrypsin][trypsin] (Mus musculus) PubMed

 8905.

Chlamydia trachomatis CPAF secretion in the cytosol of host epithelial cells is decreased. [CPAF] (Mus musculus) PubMed

 8906.

These data suggest that Pga1 plays an important role in cell wall rigidity and stability.[Pga1] (Mus musculus) PubMed

 8907.

H. pylori DsbG functions as a reductase against HP0518, a putative L,D-transpeptidase with a catalytic cysteine residue [DsbG] (Mus musculus) PubMed

 8908.

the role of GTP hydrolysis in FtsZ function and cell division [FtsZ] (Mus musculus) PubMed

 8909.

Saccharomyces cerevisiae Rad51 paralogues, the Rad55-Rad57 heterodimer, counteract the antirecombination activity of the Srs2 helicase [rad55, rad57, srs2, & rad51] (Mus musculus) PubMed

 8910.

HSV-1 gene expression from reactivated ganglia is disordered and concurrent with suppression of latency-associated transcript and miRNAs [LAT] (Mus musculus) PubMed

 8911.

covariance of the 243(rd) nucleotide of the 5'UTR with NS2 and NS3 [NS2][NS3] (Mus musculus) PubMed

 8912.

PmFKBP46 might be involved in genome packaging by viral VP15 during virion assembly [VP15] (Mus musculus) PubMed

 8913.

disease in BALB/c mice and Wistar rats infected by the rodent malaria parasite Plasmodium berghei with a gene knock out for merozoite surface protein (MSP) 7 (Mus musculus) PubMed

 8914.

Mosquito Aedes aegypti (L.) leucokinin receptor is critical for in vivo fluid excretion post blood feeding. [leucokinin receptor] (Mus musculus) PubMed

 8915.

phenotype of a conditional mutant impaired in host cell invasion and egress was pinpointed to a defect in secretion of the micronemes; sequencing identified the etiological point mutation in TgDOC2.1[TgDOC2.1] (Mus musculus) PubMed

 8916.

Pdr5p (pleiotropic drug resistance gene)is a main actor in the efficacy of lovastatin in S. cerevisiae. (Pdr5p) (Mus musculus) PubMed

 8917.

Myo8ABCDE mutant plants exhibit significant protonemal patterning defects. [Myo8A,Myo8,BMyo8C,Myo8D,Myo8E] (Mus musculus) PubMed

 8918.

PerC and GrlA independently regulate Ler expression. [PerC, GrlA, Ler] (Mus musculus) PubMed

 8919.

our data reveal a potential new role for Swap70 in regulating transition of dividing neural precursors to specified oligodendrocyte progenitor cells (Swap70). (Mus musculus) PubMed

 8920.

the structural basis of cotransporter water permeability (Mus musculus) PubMed

 8921.

These findings provide the first evidence that yeast septin proteins are acetylated and that NuA4 impacts septin dynamics.[NuA4] (Mus musculus) PubMed

 8922.

Report expression of keratin 19 and NKCC1 in developing mammary glands. (Mus musculus) PubMed

 8923.

OIP30 belongs to the RuvBL2 DNA helicase 2 subfamily, and is an OsCPK25/26-interacting protein in pollen. (Mus musculus) PubMed

 8924.

The association of Cna1 with Sec28 and Sec13 was confirmed by co-immunoprecipitation.[Calcineurin, Sec28, Sec13] (Mus musculus) PubMed

 8925.

An insertional mutant Z39P105 with a defect in sexual development was characterised and a gene encoding a putative transcription factor designated as MYT1, was identified.[MYT1] (Mus musculus) PubMed

 8926.

The peroxide regulator can positively regulate the expression of the secreted protein MF3 that contributes to the virulence in S. pyogenes[MF3],[PerR] (Mus musculus) PubMed

 8927.

the mutations of walK and clpP identified in LR5P1-V3 constitute a new combination of genetic events causing vancomycin resistance in Staphylococcus aureus. (Mus musculus) PubMed

 8928.

Deletion of the Aspergillus nidulans flavohemoglobin gene fhbA induced sexual development and decreased sterigmatocystin production. [fhbA] (Mus musculus) PubMed

 8929.

SidL is a constitutively active N5-hydroxyornithine-acetylase required for ferricrocin biosynthesis, in particular under iron-replete conditions. [SidL] (Mus musculus) PubMed

 8930.

The result provide key insights into the regulation of homolog pairing and reveal that targeting of plk-2 to the NE by meiotic chromosomes establishes the conserved linkages to cytoskeletal forces needed for homology assessment.(Polo Kinase-2) (Mus musculus) PubMed

 8931.

This work reveals unexpected functions for the conserved PLK-2, and advances understanding of how meiotic processes are properly coordinated to ensure transmission of genetic information from parents to progeny.(Polo Kinase-2) (Mus musculus) PubMed

 8932.

The role of Low-density lipoprotein receptor-related protein 2 (LRP2) in lipoprotein metabolism and egg quality traitrs is reported.[LRP2] (Mus musculus) PubMed

 8933.

The results of the binding of RecA from E. coli and T. thermophilus show adaptation to pressure and temperature at the single protein level.[RecA] (Mus musculus) PubMed

 8934.

study identifed protease chlamydial protease-like activity factor (CPAF) as the factor mediating cleavage of golgin-84 and as the target of WEHD-fmk-inhibition; results define CPAF as the first protein that is essential for replication of Chlamydia [CPAF] (Mus musculus) PubMed

 8935.

study assessed the fitness cost associated with the expression in S. aureus cells of the cfr gene alone or in combination with ermB[cfr] (Mus musculus) PubMed

 8936.

proteins that directly or indirectly affect Sup35p aggregation and [PSI(+)] formation (Mus musculus) PubMed

 8937.

The phosphorylation of the Rab Sec4p prevents interactions with its effector, the exocyst component Sec15p, and that the inhibition may be relieved by a PP2A phosphatase complex containing the regulatory subunit Cdc55p.[Sec4p] (Mus musculus) PubMed

 8938.

The second endocytic pathway, that depends on the GTPase Rho1 and the downstream formin Bni1, and the Bni1 cofactors Bud6 and Spa2. (Mus musculus) PubMed

 8939.

The nonphosphorylatable Nsk1 mutant binds prematurely to kinetochores and spindle, cementing improper k-MT attachments and leading to high rates of lagging chromosomes that missegregate.(Nsk1 & cdk1) (Mus musculus) PubMed

 8940.

The result establish Tim50 as the primary presequence receptor at the inner membrane and show that targeting signals and Tim50 regulate the Tim23 channel in an antagonistic manner.( Tim50 ) (Mus musculus) PubMed

 8941.

The results suggest that the number of CSE4 molecules exceeds the number of kinetochore-microtubule attachment sites on each chromosome and that CSE4 is not the sole determinant of kinetochore assembly sites in Saccharomyces cerevisiae.(CSE4 protein) (Mus musculus) PubMed

 8942.

The Cse4 may be associated with the CEN nucleosome, and Cse4 could be located within flanking nucleosomes at random sites that differ between chromosomes. (Mus musculus) PubMed

 8943.

the Myo4p, one of two class V myosins in budding yeast, continuously transports messenger RNA (mRNA) cargo in the cell but is nonprocessive when characterized in vitro.(Myo4p) (Mus musculus) PubMed

 8944.

Signal transduction kinases Mec1 (ATR) and Tel1 (ATM) mutants exhibit only one double-strand breaks occurs per four chromatids.[Mec1, Tel1] (Mus musculus) PubMed

 8945.

C6 inhibits the activation of IRF3 and IRF7 downstream of the kinases TBK1 and IKKepsilon, while C6 does not inhibit signalling pathways using IKKalpha for IRF7 activation. [C6] (Mus musculus) PubMed

 8946.

The HIV-1 protease (pro) gene was sequenced to view the distribution of sequence variation of a complex viral population within a host.[Hiv-1 protease] (Mus musculus) PubMed

 8947.

crystals of protein 2AB belonged to space group P4(1) or P4(3), with unit-cell parameters a = b = 90.42, c = 73.43 A, and contained two molecules in the asymmetric unit[protein 2A, protein 2B ] (Mus musculus) PubMed

 8948.

HtpG is a newly identified positive modulator of the clustered regularly interspaced short palindromic repeats system that is essential for maintaining functional levels of Cas3. (Mus musculus) PubMed

 8949.

The results of the binding of RecA from E. coli and T. thermophilus show adaptation to pressure and temperature at the single protein level.[RecA] (Mus musculus) PubMed

 8950.

The 3.0 A-resolution X-ray crystal structure of gp33 complexed with its RNA polymerase binding determinant, the beta-flap domain, was determined.[rpob] (Mus musculus) PubMed

 8951.

kinetics and thermodynamic characterization of the SePat enzyme [Pat,N(epsilon)-lysine acetyltransferase] (Mus musculus) PubMed

 8952.

Disruption of YlTPS1 drastically slowed growth at 35 degrees C. [YlTPS1] (Mus musculus) PubMed

 8953.

Recombinant betaine aldehyde dehydrogenase 2 was successfully expressed in E. coli as an N-terminal hexahistidine fusion protein and was purified using Ni Sepharose affinity chromatography[betaine aldehyde dehydrogenase 2] (Mus musculus) PubMed

 8954.

ChuZ-haemin complex crystals belonged to space group C222(1), with unit-cell parameters a = 106.474, b = 106.698, c = 52.464 A, alpha = beta = gamma = 90 degrees [ChuZ] (Mus musculus) PubMed

 8955.

Diamond-shaped crystals of DeltaN(59)sortase A diffracted to 4.0 A resolution and belonged to a tetragonal system with unit-cell parameters a = b = 122.8, c = 86.5 A, alpha = beta = gamma = 90 degrees [sortase A] (Mus musculus) PubMed

 8956.

Form I of HA3 belonged to space group R32, with unit-cell parameters a = b = 357.4, c = 249.5 A, alpha = beta = 90, gamma = 120 degrees [HA3 ] (Mus musculus) PubMed

 8957.

ROP16 deletion converts Type I tachyzoites from low to high inducers of IL-12p40, and simultaneously abrogates the suppressive effect of Toxoplasma on TLR signaling. [ROP16] (Mus musculus) PubMed

 8958.

The crystal structure of the DF complex of the prokaryotic V-ATPase of Enterococcus hirae at 2.0-A resolution, was demonstrated.[V-ATPase D, V-ATPase F] (Mus musculus) PubMed

 8959.

The characterization of another recessive resistance gene, xa25, for Xoo resistance, is reported.[Xa25] (Mus musculus) PubMed

 8960.

RSOsPR10 protein accumulated mainly in the root cortex cells after abiotic stresses and application of plant hormones. (Mus musculus) PubMed

 8961.

Unusual N-glycan structures required for trafficking Toxoplasma gondii GAP50 to the inner membrane complex regulate host cell entry through parasite motility. (Mus musculus) PubMed

 8962.

TMC647078 is a potent and speci fi c novel nucleoside inhibitor of the HCV NS5B RdRp with broad genotypic coverage and a high barrier to resistance. [NS5b] (Mus musculus) PubMed

 8963.

The N terminus of NS5A has been crystallized as a dimer, complementing the symmetry of BMS-346 and allowing a potential mode of inhibition of NS5A to be discussed. [NS5a] (Mus musculus) PubMed

 8964.

This is the first report of tet(B) in streptococci, a Gram positive bacterium. tet(B) was detected in plasmid extracts from 17/111 (15%) Streptococcus suis isolates from diseased pigs. (Mus musculus) PubMed

 8965.

The Cdc50p may play an important role for phospholipid translocation by Drs2p.(Cdc50p protein) (Mus musculus) PubMed

 8966.

This study shows that sigma A factor does not bind to the vraSR operon control region in the absence of VraR, suggesting that VraR may interact directly with this factor.[VraR] (Mus musculus) PubMed

 8967.

Study identifies Stk as an important regulator of biofilm formation and virulence of S. epidermidis, with additional involvement in purine metabolism and the bacterial stress response. [Stk] (Mus musculus) PubMed

 8968.

SrtA is required for pili cell wall covalent attachment, acting exclusively on the minor accessory pilin, representing the terminal subunit located at the base of the pilus.[Sortase A] (Mus musculus) PubMed

 8969.

IreK and IreP act antagonistically via protein phosphorylation and dephosphorylation to regulate cellular adaptation to cephalosporin-induced stress. [IreK, IreP] (Mus musculus) PubMed

 8970.

A metabolic control analysis-based strategy demonstrated that most of the lysine biosynthesis control resided on the non-cooperative and weakly feedback-inhibited Lys20 isoform.[Lys20] (Mus musculus) PubMed

 8971.

The data provide new insight into simultaneously occurring counter-acting effects of HEV ORF2 that may be part of a strategy to prevent host suicide before completion of the viral replication cycle. [ORF2] (Mus musculus) PubMed

 8972.

These results indicate that the F-actin-targeting effector VopV is involved in enterotoxic activity of type III secretion system 2-possessing bacterial pathogens.[VopV] (Mus musculus) PubMed

 8973.

NDPK levels affect growth, endocytosis and exocytosis.[NDPK C] (Mus musculus) PubMed

 8974.

EglA cDNA contains 717 bp and encoded a 238 aa endoglucanase with a predicted molecular mass of 26 kDa. [EglA] (Mus musculus) PubMed

 8975.

A single dose of insulin-like peptide 3, sufficient to stimulate egg development, rescues hemocyte proliferation. [ILP3] (Mus musculus) PubMed

 8976.

Silencing of Nox1 indicated a central role for this enzyme in both virulence and pathogenic development, while inactivation of the Nox2 gene resulted in limited sclerotial development, but the organism remained fully pathogenic.[Nox1 & Nox2] (Mus musculus) PubMed

 8977.

During Caenorhabditis elegans meiosis, loading of cohesin requires SCC-2, whereas the cohesin-related complexes condensin and SMC-5/6 can be loaded by mechanisms independent of both SCC-2 and cohesin.[scc-2] (Mus musculus) PubMed

 8978.

These results indicate that purified leukotoxin LukM/F' is not likely to contribute to the initiation of the inflammatory response and could even play an anti-inflammatory role in the mammary gland by inactivating macrophages.[LukM & LukF] (Mus musculus) PubMed

 8979.

The Deltastp was attenuated in a CD1 murine model of infection and its LD50 values was seven-fold higher than the wild type.[stp] (Mus musculus) PubMed

 8980.

[sortase A, SrtA] Both in vitro and in vivo evidence show that transpeptidase SrtA increases S. pyogenes' resistance against the bactericidal activity of human group IIA-secreted phospholipase A2 (PLA2-IIA). (Mus musculus) PubMed

 8981.

It can be concluded that rpoZ is controlled negatively by PhoP, thus connecting phosphate depletion regulation with antibiotic production and morphological differentiation in Streptomyces.[rpoZ & PhoP] (Mus musculus) PubMed

 8982.

Ndi1 expression did not trigger any inflammatory or immune response in rats.[Ndi1] (Mus musculus) PubMed

 8983.

[gp150; glycoprotein 150] A mouse transgenic for a gp150-specific T-cell receptor displays epitope-specific activation of transgenic CD4 T cells during acute and latent gamma-herpesvirus infections. (Mus musculus) PubMed

 8984.

TaFKBP13 interacts with TaRieske in the wheat thylakoid. [FKBP13] (Mus musculus) PubMed

 8985.

Isolation and identification of an AP2/ERF factor that binds an allelic cis-element of rice gene LRK6 (Mus musculus) PubMed

 8986.

The fates of absorbed light energy in PSII were quantitatively estimated by the typical energy allocation models using transgenic rice in which psbS genes were silenced by RNA interference.[PsbS1, PsbS2] (Mus musculus) PubMed

 8987.

both motors participate in early endosomes motility, with dynein transporting the organelles through the unipolar MT array near the cell ends, and kinesin-3 taking over at the beginning of the medial antipolar microtubule array. [kinesin-3] [dynein] (Mus musculus) PubMed

 8988.

uhd1 deletion strains produced ustilagic acid lacking the beta-hydroxyl group of the short-chain fatty acid.[uhd1] (Mus musculus) PubMed

 8989.

These results suggest different binding specificities of Efg1 in yeast growth and in hyphal induction and suggest a brief time window following hyphal induction, in which Efg1 exerts its repressive effect on target promoters.[Efg1] (Mus musculus) PubMed

 8990.

Surprisingly, conditional knockout indicates that TbRab7 may be non-essential in procyclic insect form trypanosomes.[Rab7] (Mus musculus) PubMed

 8991.

IRE-BP 1 transcription level was 6.7 times higher in the cypermethrin-resistant strain than in the susceptible strain. [ IRE-BP 1] (Mus musculus) PubMed

 8992.

msw, by controlling Kupffer's vesicle morphogenesis, controls lateralized behaviors related to diencephalic asymmetries.[msw] (Mus musculus) PubMed

 8993.

C. elegans mutants of the genes for the OSA/BAF250 homolog, LET-526, and the Polybromo homolog, PBRM-1, in a screen for the abnormal asymmetric cell division phenotype, were isolated.[PBRM-1, LET-526] (Mus musculus) PubMed

 8994.

Data show that the death pathway is independent of ERK but relies on activating Bad phosphorylation through the control of both kinases Cdk1 and JNK: [Bad] (Mus musculus) PubMed

 8995.

Certain Spt16 activities collaborate with histone acetylation and the activities of a Bur-kinase/Spt4-Spt5/Paf1C pathway that facilitate transcription elongation.[FACT, Bur1, Bur2, HirC] (Mus musculus) PubMed

 8996.

The study shows isolation of yeast minimal RNA polymerase II open complexes and regulation by TFIIF. [TFIIF] (Mus musculus) PubMed

 8997.

Inoculation of the long-stalk-neuraminidase virus resulted in a higher cloacal excretion in ducks and lower-level oropharyngeal excretion in chickens. (Mus musculus) PubMed

 8998.

A strong association was found between HIV-2 phenotypic tropism and gp105 V3-loop sequences, allowing for the prediction of R5- and/or X4-tropic viruses in HIV-2 infection. [HIV-2 gp105 envelope glycoprotein] (Mus musculus) PubMed

 8999.

Rem folding and cleavage is required for retrotranslocation and escape from endoplasmic reticulum-associated degradation. (Mus musculus) PubMed

 9000.

NS5 N-terminal capping enzymes binding the 5' end of the viral RNA was observed escence polarization-based RNA binding assay.[NS5] (Mus musculus) PubMed

 9001.

NhaA's binding site is relatively promiscuous and that the selectivity is determined at a later stage of the transport cycle.[NhaA] (Mus musculus) PubMed

 9002.

The energy dissipation model is applied to investigate E. coli aspartokinase III mutations to better understand the desensitization of product feedback inhibition via allostery.[Aspartokinase III] (Mus musculus) PubMed

 9003.

Data indicate that the expression of RamA promoted the development of ciprofloxacin resistant mutants of S. enterica serovar Typhimurium: [RamA] (Mus musculus) PubMed

 9004.

These results indicate that speB expression in M1 strains is induced by environmental pH changes but is not regulated by the LuxS signalling pathway. [SpeB, LuxS]] (Mus musculus) PubMed

 9005.

The stretching of actin filaments, the preferential binding of myosin II filaments to stretched actin filaments, and myosin II-dependent contraction form a positive feedback loop that contributes to the stabilization of cell polarity.[Myosin II] (Mus musculus) PubMed

 9006.

Degradation of intestinal cathelicidins is a novel function of Entamoeba histolytica cysteine proteinases in the evasion of the innate immune system in the bowel.[CP1] (Mus musculus) PubMed

 9007.

heme, a molecule from the blood digestion, triggers epimastigote proliferation through a redox-sensitive signalling mechanism, through activation of camkII.[CaMKII] (Mus musculus) PubMed

 9008.

These data suggest that PLD of Aspergillus fumigatus regulates its internalization into lung epithelial cells and may represent an important virulence factor for Aspergillus fumigatus infection.[PLD] (Mus musculus) PubMed

 9009.

These in vivo data show that Gdh1p is the primary glutamate dehydrogenase enzyme and Gdh2p and Gdh3p play evident roles during aerobic glutamate metabolism.[Gdh1, Gdh2 and Gdh3] (Mus musculus) PubMed

 9010.

The gene knockdown of CaM Kinase I delta using morpholino-based antisense oligonucleotides induced significant morphological abnormalities in zebrafish embryos. [CaM Kinase I delta] (Mus musculus) PubMed

 9011.

The ability of tomosyn to regulate neurotransmitter release in vivo depends on the physical integrity of the protein, indicating that both N- and C-terminal domains are necessary but not sufficient for effective inhibition of release in vivo.[Tomosyn] (Mus musculus) PubMed

 9012.

Thermal denaturation studies demonstrated that Ser88 and His91 both play crucial roles in the stability of the protein as their mutants showed a decrease in the melting temperature. [Arginase] (Mus musculus) PubMed

 9013.

Data suggest that the transition between two dimer architectures represents the transition between the 'on' and 'off' states of YeaZ: [YeaZ] (Mus musculus) PubMed

 9014.

Transcriptional analysis of devA and devE indicates that they are expressed at different stages of the lifecycle [devA][devE] (Mus musculus) PubMed

 9015.

the effect of residue 227 in HA on cell tropism and transmission of pH1N1 2009 [HA] (Mus musculus) PubMed

 9016.

gp120 may induce caspase-3 dependent neuronal apoptosis [gp-120] (Mus musculus) PubMed

 9017.

ClpXP proteases function in the signaling pathway of the Escherichia coli extracellular stress response. [ClpXP] (Mus musculus) PubMed

 9018.

The OsNAS genes, particularly OsNAS2(Os03g19420), show enormous potential for Fe and Zn biofortification of rice endosperm. [OsNAS2] (Mus musculus) PubMed

 9019.

structure and function of UL77 protein [UL77] (Mus musculus) PubMed

 9020.

These results may suggest that Toxoplasma gondii PL1 moves to the parasitophorous vacuole to protect parasites from nitric oxide by an undetermined mechanism.[PL1] (Mus musculus) PubMed

 9021.

Starch biosynthesis in rice endosperm requires the presence of either starch synthase I or IIIa.[SS3a] (Mus musculus) PubMed

 9022.

Phenotypic and molecular analyses of transgenic lines provided direct evidence for ALK as a key gene for gelatinization temperature.[ALK] (Mus musculus) PubMed

 9023.

OsWRKY45-1 negatively and OsWRKY45-2 positively regulates abscisic acid signalling. [WRKY45] (Mus musculus) PubMed

 9024.

Expression of VRN1 increased before flowering date, then decreased after flowering time. Expression of VRN2 was only detected in the leaves at the 3-leaf stage and in the embryo buds during seeds germination. [VRN1; VRN2] (Mus musculus) PubMed

 9025.

Overexpression of OsAGAP, an ARF-GTPase-activating protein in rice, stimulates vesicle transport from the plasma membrane to the Golgi apparatus in protoplasts and transgenic plants and induces the accumulation of early endosomes and AUX1.[AUX1, OsAGAP] (Mus musculus) PubMed

 9026.

ZRA1 is involved in zearalenone production and shares a common regulatory mode with ZEA cluster genes [ZRA1] (Mus musculus) PubMed

 9027.

DupA seems to protect against gastic ulcer and gastric cancer development, whereas a positive association was observed between the occurrence of duodenal ulcer and the presence of DupA. [DupA] (Mus musculus) PubMed

 9028.

These results suggest that Gcn2, by phosphorylating eIF2alpha, may activate translation of an unknown regulator of amino acid transporters different from Gcn4.[Gcn2] (Mus musculus) PubMed

 9029.

The present paper reported that a single amino acid substitution in the mature form of Isu1 restored many deficient functions in yfh1 or frataxin-depleted yeast cells. (Mus musculus) PubMed

 9030.

NS1 protein plays a role in the regulation of splicing of influenza virus M1 mRNA. [NS1, M1] (Mus musculus) PubMed

 9031.

KipA is an active ATPase, which is able to dimerize and move processively along microtubules with a speed of 9.48 mum/min (Mus musculus) PubMed

 9032.

Down-regulation of SBEIIb by miRNA produced a more extreme starch phenotype than hp-RNA. [SBEIIb] (Mus musculus) PubMed

 9033.

the Est1-Ccq1 interaction is critical for telomerase recruitment, while the Est1-TER1 interaction acts downstream from Ccq1-mediated recruitment to stabilize the holoenzyme at the telomere [Ccq1, TER1, Est1; no strain indicated] (Mus musculus) PubMed

 9034.

A total of seven single nucleotide polymorphisms were identified, two in SBD1 and five in SBD2.[SBD1] (Mus musculus) PubMed

 9035.

Collectively, these data support an important role of the graRS and vraFG loci in the sensing of and response to specific cationic antimicrobial peptides involved in innate host defenses. (Mus musculus) PubMed

 9036.

Results indicate that LYK3 protein localization and dynamics are altered in response to symbiotic bacteria [LYK3]. (Mus musculus) PubMed

 9037.

RNA-dependent RNA polymerase and nonstructural proteins 2, 3, and 8 are incorporated into viral particles. (NSP, RdRp) (Mus musculus) PubMed

 9038.

Overexpression of the truncated OsTPS1 enhances tolerance to drought, salt and cold in rice. (Mus musculus) PubMed

 9039.

eri-6/7 mutations cause the loss of 26-nucleotide (nt) endogenous siRNAs derived from genes and pseudogenes in oocytes and embryos, as well as deficiencies in somatic 22-nucleotide secondary siRNAs corresponding to the same loci. [ERI-6/7] (Mus musculus) PubMed

 9040.

Cg_ArsC1' is a three-cysteine containing homodimer that uses a reduction mechanism linked to the thioredoxin pathway with a k(cat)/K(M) value which is 10(3) times higher than the one of Cg_ArsC1 or Cg_ArsC2.[Cg_ArsC1', Cg_ArsC1, Cg_ArsC2] (Mus musculus) PubMed

 9041.

pigment granule aggregation signals in melanophores stimulate microtubule minus end-directed transport by increasing the number of growing microtubule plus ends decorated with CLIP-170. [CLIP-170] (Mus musculus) PubMed

 9042.

Clb5-Cdk1-dependent phosphorylation generates positive feedback that is required for switch-like Sic1 destruction [Sic1] (Mus musculus) PubMed

 9043.

studies have revealed novel regulatory elements in Cyr1 that normally repress Cyr1 activity to prevent the toxicity of unregulated high cAMP levels. (Mus musculus) PubMed

 9044.

The primary phenotype of ARP4a mutation is the mis-segregation of duplicated chromosomes with chromosome loss during nuclear division.[ARP4a] (Mus musculus) PubMed

 9045.

The authors identified IPSE/alpha-1 as a novel hepatotoxin and conclude that both IPSE/alpha-1 and omega-1 account for the majority of the hepatotoxicity secreted by Schistosoma mansoni eggs.[IPSE/alpha-1] (Mus musculus) PubMed

 9046.

These data further support the hypothesis that alternative oxidase is important in the fungal defense against oxidative stress imposed by immune cells and is relevant in the virulence of Paracoccidioides brasiliensis.[alternative oxidase] (Mus musculus) PubMed

 9047.

The authors have identified three conserved arginine residues of IF7 and IF17 that are essential for the interaction of these proteins with glutamine synthetase type I.[IF7 and IF17] (Mus musculus) PubMed

 9048.

These results show that AdcA and AdcAII play an essential and redundant role in specifically importing zinc into the pneumococcus, and that both zinc transporters are required for proper cell division and for bacterial survival during infection.[AdcAII] (Mus musculus) PubMed

 9049.

Its main activity is the conversion of InsP(6) to 5PP-Ins(1,2,3,4,6)P(5), one of the main inositol phosphates found in Entamoeba histolytica.[EhIPK1] (Mus musculus) PubMed

 9050.

data suggest MADS6 is a key player in specifying flower development via interacting with other floral homeotic genes in rice [MADS6] (Mus musculus) PubMed

 9051.

The yeast H3 mutants hht2-T80A, hht2-K79E, hht2-L70S, and hht2-E73D show normal nucleosome positioning and stability in minichromosomes.[Histone H3] (Mus musculus) PubMed

 9052.

Expression of the OmpC K12 porin in the clinical isolates lowers the microbial inhibitory concentration, consistent with modified porin function contributing to drug resistance.[OmpC] (Mus musculus) PubMed

 9053.

GcvB rewires primary transcriptional control circuits and seems to act as a distinct regulatory node in amino acid metabolism. [GcvB] (Mus musculus) PubMed

 9054.

expression, purification and characterization of RocF and its apo form [RocF] (Mus musculus) PubMed

 9055.

crystals of SecDF diffracted X-rays to 2.3 A resolution and belonged to space group C2, with unit-cell parameters a = 161.1, b = 35.8, c = 181.6 A, suggesting that they contain four molecules per asymmetric unit (Mus musculus) PubMed

 9056.

Rpn12 binds LP2 only upon correct assembly of all other lid subunits, and the Rpn12 tail then helps drive lid-base joining.(Rpn12) (Mus musculus) PubMed

 9057.

The Gal11 activator-binding domain 1 has a four-helix fold with a small shallow hydrophobic cleft at its center. (GAL11 & GCN4) (Mus musculus) PubMed

 9058.

Both crystals of capsid protease belonged to space group C2, with unit-cell parameters a = 79.6, b = 35.2, c = 49.5 A[capsid protease] (Mus musculus) PubMed

 9059.

the contribution of phoX in poly P synthesis and in TAT-system mediated stress responses [phoX] (Mus musculus) PubMed

 9060.

AKHR2a and AKHR2b are two orphan G-protein-coupled receptors for adipokinetic hormones from silkworm Bombyx mori [AKHR2a, AKRH2b] (Mus musculus) PubMed

 9061.

Study demonstrates that ZfL2-1 ORF1p has all the canonical activities associated with known ORF1ps, including self-interaction, nucleic acid binding, and nucleic acid chaperone activities. [Zfl2-1 ORF1p] (Mus musculus) PubMed

 9062.

Results indicate that CscB exhibits specificity directed toward the fructofuranosyl moiety of the glycoside to be transported. [CscB; sucrose permease] (Mus musculus) PubMed

 9063.

a new rice (Oryza sativa L.) blast resistance allele of Pid3, designated Pi25 [Pi25] (Mus musculus) PubMed

 9064.

Parasites lacking NPT1 are severely compromised in the production of gametocytes and the rare gametocytes produced are unable to differentiate into fertile gametes[NPT1] (Mus musculus) PubMed

 9065.

These findings suggest that PfCRT and PfMDR1 are carriers of antimalarial drugs. (Mus musculus) PubMed

 9066.

The authors show that in W65Scyc1 cells there is a decrease in reactive oxygen species production and an increase in caspase-like activity.[cyc1] (Mus musculus) PubMed

 9067.

Silencing of CLSP2, but not CLSP1, results in the activation of prophenoloxidase, suggesting that CLSP2 is a negative modulator of this reaction. [CLSP1 and CLSP2] (Mus musculus) PubMed

 9068.

We demonstrate that the CopA ATPase is a major pneumococcal copper resistance mechanism and provide the first evidence that the CupA protein plays a role in copper resistance. [CopA and CupA] (Mus musculus) PubMed

 9069.

Characterization of the Src/Abl hybrid kinase SmTK6 of Schistosoma mansoni [SmTK6] (Mus musculus) PubMed

 9070.

Mutations in cup-5, encoding the C. elegans Mucolipin 1 homolog, cause defects in the autophagy pathway.[CUP-5] (Mus musculus) PubMed

 9071.

Immunomicroscopy revealed EhMLCI cortical and cytoplasmic distribution in trophozoites and true colocalization with EhmhcA.[EhMLCI] (Mus musculus) PubMed

 9072.

Changes in the local DNA structure as well as in the MutS structure that appear to be correlated with base flipping, were observed.[MutS] (Mus musculus) PubMed

 9073.

GlnK is a pleiotropic regulator for morphological differentiation and secondary metabolism. [GlnK] (Mus musculus) PubMed

 9074.

A report on key mechanistic differences between the reverse transcriptases of human immunodeficiency virus type-1 and of xenotropic murine leukemia virus-related virus(reverse transcriptase). (Mus musculus) PubMed

 9075.

These findings indicate that phytochromes contribute to multiple steps in the control of internode elongation.[PhyA, PhyB, PhyC] (Mus musculus) PubMed

 9076.

FACT-L is critically involved in the formation of fertile male gametes and parasite transmission. [FACT-L] (Mus musculus) PubMed

 9077.

Identification of tvMyb3(53-180) as the essential fragment for DNA recognition and a report of the crystal structure of tvMyb3(53-180) bound to MRE-1 promoter DNA (Myb3). (Mus musculus) PubMed

 9078.

The findings underscore the possibility that contemporary alanyl-tRNA synthetase genes (ALA1 and ALA2)in V. polyspora arose relatively recently from duplication of a dual-functional predecessor of mitochondrial origin(ALA1 and ALA2). (Mus musculus) PubMed

 9079.

Results describe and compare the expression of the neuronal nuclei protein (NeuN, a.k.a. Fox-3) and doublecortin antigens in the whole brain of chicks 2 days, 8 days, and 14 weeks posthatch [NeuN]. (Mus musculus) PubMed

 9080.

Panicles of the lp-1 and lp-2 mutants show improved architecture, produce more inflorescence branches and contain more grains. [LP] (Mus musculus) PubMed

 9081.

extent and frequency of allelic diversity at the Pvmsp-1 locus in field isolates in Republic of Korea during the past decade; 6 Pvmsp-1 gene types (SKOR-I to SKOR-VI) were identified as unique combinations of type sequences in each variable bloc [msp-1] (Mus musculus) PubMed

 9082.

cloning and characterization of RPS29; transcriptional level of RPS29 was upregulated in deltamethrin (DM) resistant Cx. p. pallens; study provides evidence that RPS29 might be associated with fitness cost of DM resistance (Mus musculus) PubMed

 9083.

Genome wide cloning of maize meiotic recombinase Dmc1 and its functional structure through molecular phylogeny. [Dmc1] (Mus musculus) PubMed

 9084.

The expression of xen1 starts on a later stage of development 47-48, while the gene xen2 is expressed on all stages of development with the same increase starting from stage 0-5. [xen1] [xen2] (Mus musculus) PubMed

 9085.

yeast cells control RNR function during iron deficiency by redistributing the Rnr2-Rnr4 small subunit from the nucleus to the cytoplasm [Rnr2 & Rnr4] (Mus musculus) PubMed

 9086.

the importance of two invariant residues, Gln2 and Ser65 in ubiquitin (Mus musculus) PubMed

 9087.

study reports that ICP0 induces the widespread proteasome-dependent degradation of SUMO-conjugated proteins during infection and has properties related to those of cellular SUMO-targeted ubiquitin ligases ICP0] (Mus musculus) PubMed

 9088.

VocC is required for the efficient secretion of VopC via type III secretion system 2. [VopC] (Mus musculus) PubMed

 9089.

Sapp1p displays enzyme activity prior to secretion, and therefore, it is probably fully folded within the upper layer of the cell wall. [Sapp1p] (Mus musculus) PubMed

 9090.

Rice and Arabidopsis CFL1 negatively regulate cuticle development by affecting the function of HDG1, which regulates the downstream genes BDG and FDH. [HDG1; CFL1] (Mus musculus) PubMed

 9091.

Nitric oxide (NO)-mediated GS posttranslational inactivation is related to metabolite channeling to boost the nodule antioxidant defenses in response to NO.[GS] (Mus musculus) PubMed

 9092.

p38 MAPK signaling regulates neutrophil infiltration in acute lung injury induced in mice by streptococcal M1 protein.[M1 PROTEIN] (Mus musculus) PubMed

 9093.

These findings newly indicate a regulatory role of beta and beta' subunits of CK2 in the nutrient response.[CK2 beta, CK2 beta'] (Mus musculus) PubMed

 9094.

A structure for Zea mays CK2beta1 by homology modeling, is predicted.[CK2beta] (Mus musculus) PubMed

 9095.

LAX2 encodes a nuclear protein that is required for the process of axillary meristem formation and acts together with LAX1. [LAX2] (Mus musculus) PubMed

 9096.

complex regulatory mechanisms underlie functional matA expression during self-fertilization and sexual reproduction in A. nidulans[matA] (Mus musculus) PubMed

 9097.

EspT induces expression of cyclooxygenase-2 in U937 human macrophages by activating the nuclear factor kappa-B, the extracellular signal-regulated kinases 1 and 2 (Erk1/2) and c-Jun N-terminal kinase (JNK) pathways. [EspT] (Mus musculus) PubMed

 9098.

(cortisol) There was a significant increase in cortisol at birth in lambs born to obese ewes related to an increase in leptin in the first day of life. (Mus musculus) PubMed

 9099.

The data of this study demonistrated that the apobec2b is essential for retina and optic nerve regeneration. (Mus musculus) PubMed

 9100.

These results show the possibility that polka dots (Xpod) is involved in the establishment of a certain subpopulation of ionocytes under hypertonic conditions.[Xpod] (Mus musculus) PubMed

 9101.

Depolarization-induced charge movement causes a conformational change in the M(2) receptor that may be responsible for the voltage-dependence of agonist binding.[M2R] (Mus musculus) PubMed

 9102.

Rev1 is biologically relevant and is required specifically for dCMP insertion during the bypass of endogenous AP sites [Rev1] (Mus musculus) PubMed

 9103.

SAGA-associated Sgf29p facilitates the recruitment of TBP (and hence transcription) without altering the global structural integrity of SAGA in vivo [Sgf29p][TBP] (Mus musculus) PubMed

 9104.

The work described herein provides a platform for photochemical radical initiation and study of proton-coupled electron transfer (PCET) in the beta2 subunit of RNR.[RNR beta2] (Mus musculus) PubMed

 9105.

Mph1 is a sufficient marker for recruitment of Bub1. Mad1, in contrast, requires an additional condition/component for stable association with kinetochores.[Mph1, Bub1, Mad1] (Mus musculus) PubMed

 9106.

the structural basis and mechanistic implications of TLR5-flagellin recognition [flagellin] (Mus musculus) PubMed

 9107.

P11 could bind to A. phagocytophilum and thus facilitate its infection of tick cells.[P11] (Mus musculus) PubMed

 9108.

novel streptogramin A, pleuromutilin, and lincosamide resistance determinant, Vga(E), was identified; vga(E) gene encoded a 524-amino-acid protein belonging to the ABC transporter family [vga(E)] (Mus musculus) PubMed

 9109.

The deletion of Candida glabrata genes PWP7 and AED1 results in a significant reduction in adherence to endothelial cells compared with the wild-type parent.[PWP7 and AED1] (Mus musculus) PubMed

 9110.

As a consequence, the disruption of ZDS3 resulted in complete loss of virulence in a mouse cryptococcosis model.[ZDS3] (Mus musculus) PubMed

 9111.

the duplication of a chromosomal segment containing mdr1 is selected by mefloquine, lumefantrine, and artemisinin from a complex P. chabaudi genetic mixture. [mdr1] (Mus musculus) PubMed

 9112.

the nucleus-encoded TDA1 factor is specifically required for translation of the chloroplast atpA transcript that encodes subunit alpha of ATP synthase [TDA1] (Mus musculus) PubMed

 9113.

This finding indicates that the energy required for PvuA1 to transport ferric vibrioferrin across the outer membrane is provided by the TonB2 system.[PvuA1 & TonB2] (Mus musculus) PubMed

 9114.

a signal peptide is required for the assembly of a bacterial adhesin FadA [FadA] (Mus musculus) PubMed

 9115.

SIZ-dependent sumoylation may modulate the activity of multiple proteins to promote efficient nucleotide excision repair [SUMO] (Mus musculus) PubMed

 9116.

Srs2 promotes checkpoint recovery by removing Rad51 after DNA repair [Srs2] (Mus musculus) PubMed

 9117.

a post-translational modification to the inactive enzyme during hypoxia [Sod1p] (Mus musculus) PubMed

 9118.

These findings suggest that the constitutive activation of STAT6 by Tip in T-cells may contribute to IL-2-independent T-cell transformation by herpesvirus saimiri.[Tip] (Mus musculus) PubMed

 9119.

These results indicate that the acylation and cholesterol-binding motifs in M2 are not crucial for the replication of influenza virus in cell culture, indicating that other factors can target M2 to the budding site.[M2] (Mus musculus) PubMed

 9120.

HTLV-1 transmission through cellular conduits induced by the viral accessory protein p8. [p8] (Mus musculus) PubMed

 9121.

The fibrinogen-binding protein (Fbl) of Staphylococcus lugdunensis is not involved in the invasion of cells as ruled out by an isogenic fbl mutant.[Flb] (Mus musculus) PubMed

 9122.

WR1 is a positive regulator of wax synthesis related genes , and this regulation, distinct from its homology regulator of WIN1/SHN1 in cutin synthesis, subsequently contributes to reduced water loss and enhanced drought tolerance. (WR1) (Mus musculus) PubMed

 9123.

[dihydrofolate reductase DHFR] Two modified 23S rRNA ribosomes suppress UAG codons in E. coli DHFR in the presence of beta-alanyl-tRNA. (Mus musculus) PubMed

 9124.

These results suggest that CagA C-terminal domain EPIYA repeats directly interact with cholesterol-rich microdomains that induce efficient IL-8 secretion in the epithelial cells.[CagA] (Mus musculus) PubMed

 9125.

ApbC mutant is unable to grow on tricarballylate as a carbon source. [ApbC] (Mus musculus) PubMed

 9126.

new structural and functional insight into a carbohydrate-mediated component of the pneumococcus-host interaction mediated through StrH is provided. [StrH] (Mus musculus) PubMed

 9127.

[RrgA; RrgB; RrgC] Sortase-2 catalyzes the formation of both RrgA-RrgB and RrgB-RrgC structural complexes. (Mus musculus) PubMed

 9128.

MtlA protein expression is regulated posttranscriptionally by the MtlS small regulatory RNA.[MtlS] (Mus musculus) PubMed

 9129.

Results sugggest that Ndc10 provides a central platform for inner-kinetochore assembly: [Ndc10] (Mus musculus) PubMed

 9130.

Bacterial two-hybrid and far-Western analysis indicated that Mip interacted with PrtA directly.[PrtA] (Mus musculus) PubMed

 9131.

the structure of IRP1 in complex with transferrin receptor 1 B iron responsive elements [IRP1] [transferrin receptor 1 B] (Mus musculus) PubMed

 9132.

LytF is a functional analogue of CbpD and is an essential part of the natural transformation system.[LytF] (Mus musculus) PubMed

 9133.

Vimentin- like transcript was expressed in both chordocytes and chordoblasts, whereas the elastin- like transcript was uniquely expressed in the chordoblasts lining the notochordal sheath.[Elastin] (Mus musculus) PubMed

 9134.

Using molecular dynamics simulations, the catalytic roles of Arg197 and Thr183 were analyzed. [sortase A] (Mus musculus) PubMed

 9135.

VanN-type resistance was transferable by conjugation to E. faecium. This is the first report of transferable D-Ala-D-Ser-type resistance in E. faecium. [VanN] (Mus musculus) PubMed

 9136.

Telomerase regulatory subunit Est3 in Candida species physically interacts with the TEN domain of TERT and telomeric DNA [Est3, TRT1] (Mus musculus) PubMed

 9137.

anthoMATE1 and anthoMATE3 are involved in anthocyanin transport mechanisms.[anthoMATE3, anthoMATE1] (Mus musculus) PubMed

 9138.

The phosphotransferase VanU, which phosphorylates and activates VanO, repressed expression of the Qrr sRNAs and stabilized vanT mRNA.[VanU, VanO and Qrr] (Mus musculus) PubMed

 9139.

ROP is the first example of a zinc finger transcription factor involved in the catabolite repression of phosphoenolpyruvate carboxykinase in yeast cells cultured under biotin- or PC-deficient and glucose-abundant conditions.[ROP] (Mus musculus) PubMed

 9140.

Xog1p is one of the LL37/hBD-3 targets, and elevated beta-1,3-exoglucanase activity reduces C. albicans adhesion to plastic.[Xog1p ; candida albicans.] (Mus musculus) PubMed

 9141.

The crystal RrgB fibre is a compelling model for deciphering the molecular details required to generate the pneumococcal pilus. (Mus musculus) PubMed

 9142.

chloroplast preproteins as a general class of HSP90 client proteins in plants using HOP and FKBP as novel cochaperones [HSP90][FKBP][HOP] (Mus musculus) PubMed

 9143.

OsGL1-1 is involved in leaf cuticular wax and cuticle membrane [OsGL1-1] (Mus musculus) PubMed

 9144.

Results suggest a possible mechanism for ATP-dependent DNA tethering and DNA double-strand break processing by the Mre11:Rad50 complex (MRE11, Rad50). (Mus musculus) PubMed

 9145.

Although Dcp2 can interact with Upf1, this interaction is indirect and is largely dependent on the Edc3 protein, which interacts with the N-terminal domain of Upf1 and Pat1 has an independent interaction with the N-terminus of Upf1.[Upf1, Edc3, Pat1] (Mus musculus) PubMed

 9146.

proteotoxic stress, caused by transient Hsp90 inhibition or heat shock, markedly increased chromosome instability to produce a cell population with high karyotype diversity [Hsp82] (Mus musculus) PubMed

 9147.

interaction between Gal3p-Gal80p proteins occurs only when Gal3p is in a "closed" state induced by ligand binding[Gal3 and Gal80; strain not listed] (Mus musculus) PubMed

 9148.

Heptatitis c virus (HCV) specific E2 and host CD81 antibodies reduce HCV pseudoparticle entry.[E2] (Mus musculus) PubMed

 9149.

Candida glabrata Yps1 is required for cell growth at elevated temperatures, and that the heat-induced expression of YPS1 is regulated predominantly by the calcineurin-Crz1 pathway and partially by the Slt2 MAPK pathway. [YPS1, CRZ1, and SLT2] (Mus musculus) PubMed

 9150.

Both slnA and drkA are essential for the generation of yeast cells in vivo, with slnA required for the germination of conidia and drkA required for dimorphic switching during macrophage infection.[slnA and drkA] (Mus musculus) PubMed

 9151.

the direct phosphorylation of Ccq1 Thr 93 by Tel1 and Rad3 is involved in the recruitment of telomerase to elongate telomeres [Tell(ATM), Rad3(ATR), Ccq1;different strain] (Mus musculus) PubMed

 9152.

crystal structure of a botulinum neurotoxin (BoNT/A)in complex with nontoxic nonhemagglutinin(NTNHA) protein at 2.7 A; studies show NTNHA provides large and multivalent binding interfaces to protect BoNT/A from gastrointestinal degradation [BoNT/A; NTNHA] (Mus musculus) PubMed

 9153.

identified gene inducing male-specific wing size and shape differences between species; results indicate how changes in regulation of upd-like are involved in microevolution of morphologic and sex-specific differences between species[upd-like NV21594] (Mus musculus) PubMed

 9154.

These results highlight that in tissue culture, function of elongation factor G in the apicoplast can be diminished, but during an animal infection, translation in the apicoplast must be fully functional.[elongation factor G] (Mus musculus) PubMed

 9155.

We show that the syntenic A. gossypii homolog of MFa1 (AFL062w) does not encode a mature a-factor peptide, but identified another gene, AAR163c, which encodes a candidate a-specific mating pheromone and is thus reannotated as AgMFalpha2. [AgMFalpha2] (Mus musculus) PubMed

 9156.

The regulation of copper homeostasis by Cuf1 is realized by its subcellular localization.[Cuf1] (Mus musculus) PubMed

 9157.

As anticipated, deletion of ccpA derepressed tricarboxylic acid cycle activity and inhibited biofilm formation; however, ccpA deletion had only a modest effect on icaADBC transcription.[ccpA] (Mus musculus) PubMed

 9158.

crystals of dextranase diffracted to a resolution of 1.6 A and belonged to space group P2(1), with unit-cell parameters a = 53.2, b = 89.7, c = 63.3 A, beta = 102.3 degrees [dextranase] (Mus musculus) PubMed

 9159.

crystals of Serine-rich repeat protein 1 diffracted to 3.8 A resolution using synchrotron radiation and belonged to space group P2(1), with unit-cell parameters a = 47.56, b = 59.48, c = 94.71 A, beta = 93.95 degrees [Serine-rich repeat protein 1] (Mus musculus) PubMed

 9160.

Identification of the key residues, His121, Asn145 and Glu164, which are crucial for Spd1 nucleolytic activity (Spd1). (Mus musculus) PubMed

 9161.

CgArsR-C15/16/55S was expressed, purified, crystallized and X-ray diffraction data were collected to 1.86 A resolution[CgArsR-C15/16/55S] (Mus musculus) PubMed

 9162.

crystals of 130K replication protein belonged to the orthorhombic space group P2(1)2(1)2(1), with unit-cell parameters a = 85.8, b = 128.3, c = 40.7 A.[130K replication protein] (Mus musculus) PubMed

 9163.

The collective findings of this study provide insight into the regulation of the bamboo mosaic virus satellite RNA (satBaMV)-P20 ribonucleoprotein complex by phosphorylation during satBaMV co-infection (P20). (Mus musculus) PubMed

 9164.

the expression of igf-I, gh and ghr1 is involved in the regulation of growth rate at larval stages in T. rubripes [growth hormone, growth hormone receptor I and insulin-like growth factor I] (Mus musculus) PubMed

 9165.

the mechanism of GUN4 activation of magnesium chelatase [GUN4][Ch1H] (Mus musculus) PubMed

 9166.

Thus, Trichomonas vaginalis pyruvate:ferredoxin oxidoreductase A (PFOA) is an example of a surface-associated cell-binding protein that lacks enzyme activity and that is involved in cytoadherence.[pfoA] (Mus musculus) PubMed

 9167.

Mutations in the core region and NS5A region of hepatitis C virus are associated with peginterferon responsiveness in chronic hepatitis C. (Mus musculus) PubMed

 9168.

Deletion of PGA26 may cause an imbalance in the morphological switching ability of Candida, leading to attenuated dissemination and infection. [PGA26] (Mus musculus) PubMed

 9169.

H3 tail acts as an integrating platform for signals that influence DNA methylation, in part through methylation of H3K9.[histone H3] (Mus musculus) PubMed

 9170.

cholesterol impedes the membrane association and destabilizing activities of membrane-proximal external region of gp41.[gp41] (Mus musculus) PubMed

 9171.

The free energy barrier for water-mediated proton transport between the two proton gating residues Glu(203) and Glu(148) in the ClC-ec1 antiporter, including the Grotthuss mechanism of proton hopping, was calculated.[ClC-ec1] (Mus musculus) PubMed

 9172.

A basal signalling module providing activation of Ras at the leading edge, which is sufficient for chemotaxis, was identified.[Ras] (Mus musculus) PubMed

 9173.

TTV ORF1 protein may be a nuclear protein which contains 2 non-regular secondary structure region. 265aa to 486aa and 510aa to 679aa may be the two fragments to construct the plasmids, which would be prepared for future hybrid experiments [ORF1 protein] (Mus musculus) PubMed

 9174.

miR-449 strongly accumulated in multiciliated cells in human airway epithelium and Xenopus laevis embryonic epidermis, where it triggered centriole multiplication and multiciliogenesis by directly repressing the Delta/Notch pathway.[review: miR-449] (Mus musculus) PubMed

 9175.

Ole1 (fatty acid desaturase) regulates glucotoxicity by converting glucose into lipid droplets. [Ole1] (Mus musculus) PubMed

 9176.

PbP27 expression was examined at the transcriptional and translational levels in the mycelia and yeast forms of different isolates of the species complex of P. brasiliensis (PbP27). (Mus musculus) PubMed

 9177.

Pob3 histone binding was modification-independent, implicating the loop of Rtt106 in H3K56ac-specific recognition in vivo.[Rtt106] (Mus musculus) PubMed

 9178.

Structures of the central domain in two different oligomerization states for a small terminase from the T4 family of phages, are reported.[Terminase] (Mus musculus) PubMed

 9179.

Analysis of the data elucidated a new role of NCp7 by facilitating DNA-directed DNA synthesis during reverse transcription by HIV-1 reverse transcriptase. [NCP7 protein, HIV-1] (Mus musculus) PubMed

 9180.

The hSIK1 appears to be of potential relevance within vascular smooth muscle cells function and blood pressure regulation. (Mus musculus) PubMed

 9181.

FliC could enhance specific IgA responses in saliva and protective ability of pGJA-P VAX, providing an effective mucosal adjuvant candidate for intranasal immunization of an anti-caries DNA vaccine [FliC] (Mus musculus) PubMed

 9182.

The protein encoded by hemN1 appears to be the major enzyme that is involved in anaerobic heme synthesis of Shewanella oneidensis.[hemN1] (Mus musculus) PubMed

 9183.

A predicted basic helix-loop-helix protein-encoding gene designated ecdR (early conidiophore development regulator) plays a major role in conidiation in Aspergillus oryzae(ecdR). (Mus musculus) PubMed

 9184.

Findings indicate that multicilin initiates multiciliate cell differentiation in diverse tissues, by coordinately promoting the transcriptional changes required for motile ciliogenesis and centriole assembly [multicilin] (Mus musculus) PubMed

 9185.

Using limited proteolysis coupled with mass spectrometric analyses, the authors defined CheA(163-256) to be the CheS binding domain, which overlaps with the N-terminal part of the CheY2 binding domain (CheA(174-316)).[CheA & CheS] (Mus musculus) PubMed

 9186.

The authors propose a model for RpoS regulation of motility gene expression that involves (i) attenuation of H-NS repression by IHF and (ii) RpoS-dependent transcription initiation resistant to H-NS.[RpoS & H-NS] (Mus musculus) PubMed

 9187.

This study aimed at gainin an enhanched view of ion binding to the extraceullular end of the KcsA ion channel selectivity filter.[KcsA] (Mus musculus) PubMed

 9188.

The transition state structure is able to descend down the glycosylation pathway through the critical combination of Asp214 (HOMO), ring oxygen (LUMO), and Glu212 (HOMO), anomeric carbon (LUMO) interactions. [cellobiohydrolase I] (Mus musculus) PubMed

 9189.

Accordingly, inactivation of yjbH in Staphylococcus aureus increased the level of Spx protein and transcription of the Spx-regulated gene trxB.[yjbH] (Mus musculus) PubMed

 9190.

Here the authors present evidence that bistable expression of the type 1 pilus is mediated by the positive-feedback loop controlling rlrA expression.[rlrA] (Mus musculus) PubMed

 9191.

we report the identification of a nuclear localization domain in Myb2, spanning nearly the entire R2R3 domain. [Myb2] (Mus musculus) PubMed

 9192.

the major role of EzrA in S. aureus [EzrA] (Mus musculus) PubMed

 9193.

nuclear pore complex mediates binding of the Mig1 repressor to target promoters [Mig1] (Mus musculus) PubMed

 9194.

We identify the ssDNA-binding protein, I3 as a viral factor that interacts and co-localizes with the eIF4F scaffold protein, eIF4G in VACV infected cells. [I3] (Mus musculus) PubMed

 9195.

TRAIL dependent fratricidal killing of gp120 primed hepatocytes by HCV core expressing hepatocytes (Mus musculus) PubMed

 9196.

The target-of-rapamycin (TOR) growth pathway modulates cilia size and function during zebrafish development.[Torc1] (Mus musculus) PubMed

 9197.

The FusB family are two-domain metalloproteins, the C-terminal domain of which contains a four-cysteine zinc finger with a unique structural fold.[FusB] (Mus musculus) PubMed

 9198.

Residues that confer differences in substrate specificity between Drs2 and Dnf1, Saccharomyces cerevisiae P4-ATPases that preferentially flip phosphatidylserine and phosphatidylcholine (PC), respectively, were identified.[Drs2, Dnf1] (Mus musculus) PubMed

 9199.

tra1 alleles that are selectively defective for interaction with Gal4 in vivo [Gal4 interaction defective (GID) mutants], were characterized.[Gal4, Tra1] (Mus musculus) PubMed

 9200.

cryo-electron microscopy reconstructions of eukaryotic and archaeal ribosome recycling complexes containing ABCE1 and the termination factor paralogue Pelota [Rli1 & Dom34] (Mus musculus) PubMed

 9201.

Crystal structures of two bacterial E3s, Salmonella SopA and Escherichia coli NleL, both in complex with human E2 UbcH7, are reported.[NleL] (Mus musculus) PubMed

 9202.

The pathogenicity of eaeA was moderate attenuated and the pathogenicity of stx2 and ehxA were highly attenuated. [Stx2,eaeA ] (Mus musculus) PubMed

 9203.

Rhcg1 and NHE3b are involved in ammonium-dependent sodium uptake by zebrafish larvae acclimated to low-sodium water. (Mus musculus) PubMed

 9204.

a mutation in the acceptor site of the second intron of SV2A (the gene encoding synaptic vesicle glycoprotein 2A) is causing photosensitive reflex epilepsy in a unique vertebrate model, the Fepi chicken [SV2A] (Mus musculus) PubMed

 9205.

XIAP may act as a regulator of follicular atresia in the sheep ovary by preventing activation of caspase 3. [XIAP] (Mus musculus) PubMed

 9206.

findings suggest that although the hemagglutinin D222G mutation does not influence virus transmission, it may be considered a molecular marker for enhanced replication in certain cell types[HA] (Mus musculus) PubMed

 9207.

Cj0561c was more effectively induced by bile salts than cmeABC and taurocholate was superior to cholate as an inducer of transcription. [Cj0561] (Mus musculus) PubMed

 9208.

Edc3 & Scd6 stimulate decapping in vitro, presumably by preventing the Dcp1:Dcp2 complex from adopting an inactive conformation. Protein interactions via LSm & HLM domains were identified.[Scd6] (Mus musculus) PubMed

 9209.

(neuron-specific enolase) No correlation is found between neuron-specific enolase (NSE) levels and outcome following spinal cord decompression. The initial degree of paresis is not a prognostic factor to predict outcome. (Mus musculus) PubMed

 9210.

preventing gadd153 activation protects against Alzheimer's disease related to cholesterol oxidized products.[GADD153] (Mus musculus) PubMed

 9211.

in trout embryo, N-cadherin is associated with muscle cell immaturity while M-cadherin is associated with muscle cell maturation and differentiation and this during the two successive phases of myogenesis [n-cadherin, M-cadherin] (Mus musculus) PubMed

 9212.

These data suggest that the ClpXP adaptor YjbH has more target proteins than previously thought, and that oxidative burst and beta-lactam resistance mechanisms of S. aureus are closely linked. [YjbH] (Mus musculus) PubMed

 9213.

Results showed that SatAB is a narrow-spectrum fluoroquinolone exporter (norfloxacin and ciprofloxacin), susceptible to reserpine,esistance. [SatA, SatB, SmrA] (Mus musculus) PubMed

 9214.

Expression levels of MYB genes (MYB13-1, MYB13-2 and MYB13-3) were found to be positively correlated with the mRNA levels of sucrose:sucrose 1-fructosyltransferase and sucrose:fructan 6-fructosyltransferase in wheat stems.[MYB13-1] (Mus musculus) PubMed

 9215.

OsNST1 is important for the overall structure of cell wall polysaccharides. Mutants show altered orientation of cellulose microfibrils. (Mus musculus) PubMed

 9216.

This study supports the involvement of the Pfnhe-1 gene in the modulation of the in vitro quinine response when associated with mutated Pfcrt and Pfmdr1 genes.[nhe-1] (Mus musculus) PubMed

 9217.

Ligustrazine has notable protective effects on pulmonary ischemia/reperfusion injury inhibiting Fas/FasL mRNA express in lung tissue and decreasing apoptosis. (Mus musculus) PubMed

 9218.

These results demonstrate that ggFcR has a contact site to IgY which closely resembles that of human IgG bound to FcR.[ggFcR, IgY] (Mus musculus) PubMed

 9219.

The presence of jhp0945 was significantly associated with gastric ulcer, duodenal ulcer, and gastric cancer (odds ratios [95% confidence intervals]: 2.27 [1.04 to 4.98], 1.86 [1.03 to 3.34], and 1.92 [1.03 to 3.56], respectively).[jhp0945] (Mus musculus) PubMed

 9220.

The fusB resistance determinant in S. epidermidis was highly associated with phage-related resistance islandss. [Fus] (Mus musculus) PubMed

 9221.

The first direct observation of the interaction between chemoreceptor and CheW.{CheW] (Mus musculus) PubMed

 9222.

conserved element in RNA polymerase II promoters [RNA polymeras II] (Mus musculus) PubMed

 9223.

A lack of gp180 encoded by Bo10 had no impact on the establishment and maintenance of BoHV-4 latency, but markedly sensitized virions to neutralization by immune sera[Bo10] (Mus musculus) PubMed

 9224.

human PDZ-cellular ligands of NS1 protein [NS1] (Mus musculus) PubMed

 9225.

Solution structure of the HIV-1 exon splicing silencer 3.[ ESS3 (Exon splicine silencer 3); HIV-1] (Mus musculus) PubMed

 9226.

N-terminally myristoylation of Gag allows Env-independent budding of viral particles. (Mus musculus) PubMed

 9227.

[heat-labile enterotoxin B] A hybrid peptide of E coli enterotoxin B subunit fused with synapsin carboxyl domain up-regulates expression of anti-inflammatory cytokines and diminishes myelin basic protein-specific T-helper cell responses in lymph nodes. (Mus musculus) PubMed

 9228.

These results show that the XylB, RbtT, and MtlD proteins allow the growth of Corynebacterium glutamicum on D-arabitol and that D-arabitol metabolism is subject to arabitol-dependent derepression by AtlR.[AtlR] (Mus musculus) PubMed

 9229.

polymerase activity of VP1 [VP1] (Mus musculus) PubMed

 9230.

GAL102 in C. albicans encodes a homolog of dTDP-glucose 4,6-dehydratase, an enzyme that affects cell wall properties as well as virulence of many pathogenic bacteria[Gal102] (Mus musculus) PubMed

 9231.

GF14e-silenced plants show enhanced resistance to bacterial and fungal rice diseases. [GF14e] (Mus musculus) PubMed

 9232.

MSP1-19 is not a major target of growth inhibitory antibodies [MSP1] (Mus musculus) PubMed

 9233.

the specificity of NEDD8-specific peptidase SENP8 [NEDD8] (Mus musculus) PubMed

 9234.

We biochemically characterized a heat stable PulA produced from T. neapolitana by examining its substrate specificity and its mode of action in transglycosylation reactions. [PulA] (Mus musculus) PubMed

 9235.

WbaP (UDP-galactose:Und-P galactose-1-phosphate transferase) C-terminal domain contains all the essential motifs to catalyze the synthesis of the Und-P-P-Gal molecule that primes the biosynthesis of bacterial surface glycan (Mus musculus) PubMed

 9236.

A crl5 ral1 double mutant displayed an additive phenotype, showing that the formation of each root is regulated by different genetic mechanisms in rice. [CRL5] (Mus musculus) PubMed

 9237.

gp120 induces microglia neurotoxic activity by enhancing microglia outward K+ (potassium) current. (Mus musculus) PubMed

 9238.

Radix astragali injection inhibits fibroblast proliferation in hypertrophic scars through down-regulating mRNA expression and protein synthesis of TGF-beta and Smad3. [Smad3] (Mus musculus) PubMed

 9239.

the kinetics of transient events in Saccharomyces cerevisiae RFC-catalyzed PCNA loading, including ATP-induced RFC activation, PCNA opening, ptDNA binding, ATP hydrolysis, PCNA closing, and PCNA.ptDNA release.[RFC protein] (Mus musculus) PubMed

 9240.

ATP binding and hydrolysis switch RFC between conformations with high and low affinities, respectively, for open PCNA and ptDNA, and thus bookend the clamp loading reaction.[RFC protein] (Mus musculus) PubMed

 9241.

The study reports a real-time measurement of ATP-induced conformational changes in the terminase of bacteriophage T7. [terminase] (Mus musculus) PubMed

 9242.

This study provides insight into the structure and function of the CBM33 family of enzymes, which, together with their fungal counterpart called GH61, currently receive considerable attention in the biomass processing field.[EfCBM33A enzyme] (Mus musculus) PubMed

 9243.

These crystal structures depicted that DrRRA has the structural features of the OmpR/PhoB subfamily and were also confirmed by SAXS investigation of the protein in solution. [DrRRA] (Mus musculus) PubMed

 9244.

These results suggest an ancestral role for TGA1-like genes in early spikelet development.[TGA1] (Mus musculus) PubMed

 9245.

metacaspase-3 was biochemically validated as a bona fide SUMOylation substrate in Trypansosoma cruzi (Mus musculus) PubMed

 9246.

The data provide evidence for the biological function of OsARF12, which is implicated in regulating root elongation.[OsARF12] (Mus musculus) PubMed

 9247.

Complete coding sequence, sequence analysis and transmembrane topology modelling of Trypanosoma brucei rhodesiense putative oligosaccharyl transferase (TbOST II). (Mus musculus) PubMed

 9248.

we describe the identification and characterization of a novel open reading frame (ORF4) encoded by the murine norovirus and propose the name virulence factor 1, VF1 for this protein (Mus musculus) PubMed

 9249.

studies supported the role of Ada2 in the direct regulation of capsule and mating responses [Ada2] (Mus musculus) PubMed

 9250.

aim of this work was to investigate the role of a unique sterol-sensing domain-containing protein, TgNCR1, expressed by T. gondii (Mus musculus) PubMed

 9251.

clearance of sumoylated Gcn4 requires the protein kinase and Mediator complex subunit Srb10 [Gcn4 and Srb10, strain not found] (Mus musculus) PubMed

 9252.

Using Colocalization single-molecule spectroscopy was used to directly visualize on single DNA molecules all major steps in initiation, including polymerase binding, open complex formation, transcript production, and sigma54 departure. [sigma 54] (Mus musculus) PubMed

 9253.

found that Ndt80p directly regulated its target genes, such as YHB1, via the mid-sporulation element [Ndt80p] (Mus musculus) PubMed

 9254.

PfAlba3 binds to the telomeric and subtelomeric regions as well as to var gene promoter (PfAlba3). (Mus musculus) PubMed

 9255.

mutation of 3 of the 275 residues in Lhp1 alters its import pathway to a Kap121-dependent process [Lhp1][Kap121] (Mus musculus) PubMed

 9256.

insight into the complexity of Hsp60 function [Hsp60] (Mus musculus) PubMed

 9257.

Rf2 encodes a protein consisting of 152 amino acids with a glycine-rich domain. Expression of Rf2 mRNA was detected in developing and mature anthers. An RF2-GFP fusion was shown to be targeted to mitochondria [Rf2] (Mus musculus) PubMed

 9258.

Alcohol promotes the myocardial oxidative stress and fibrosis through an elevated expression of PYK2 and a lowered expression of caveolin-1. [PYK2] (Mus musculus) PubMed

 9259.

analysis reveals how the structure responds to linker separation and suggests a mechanism of MotB activation that entails linker unfolding and rotational displacement of MotB transmembrane helices[MotB] (Mus musculus) PubMed

 9260.

Thermus thermophilus L1 mutant lacking one residue in the fragment corresponding to the hinge was obtained and its crystal structure was solved[ribosomal L1 protein] (Mus musculus) PubMed

 9261.

structure of the complex revealed a GGDEF-domain of diguanylate cyclase dimer cross-linked by two molecules of c-di-GMP at the strongly conserved active sites[diguanylate cyclase ] (Mus musculus) PubMed

 9262.

protein fold is dominated by an eight-stranded beta-sandwich and identifies SmLip as a new member of the transthyretin family of proteins[ Lip] (Mus musculus) PubMed

 9263.

These results indicate that V. vulnificus AphB is involved in the IL-8 production via an NF-kappaB dependent pathway in human intestinal epithelial cells.[AphB] (Mus musculus) PubMed

 9264.

crystal structure of O-Acetylhomoserine sulfhydrylase(MetY) determined at 2.2 A; structure of MetY, together with biochemical data, provides insight into mechanism of sulfur transfer to a small molecule via a protein thiocarboxylate intermediate [MetY] (Mus musculus) PubMed

 9265.

It was concluded that two amino acids in avian-origin PB1, 473V and 598P, contribute to the polymerase activity of the H5N1 virus, especially in mammalian cells. (Mus musculus) PubMed

 9266.

hMR expressed by vaginal epithelial cells has high affinity for HIV gp120 and this binding induces production of matrix metalloproteinases.[gp120] (Mus musculus) PubMed

 9267.

Transcriptional regulation of genes encoding rice 60S ribosomal protein L32 (rpL32) in response to salt stress has been studied.[rpL32] (Mus musculus) PubMed

 9268.

These data provide compelling biochemical evidence for a P(5A)-type Cta4 ATPase as an essential component of Ca(2+) transport system.[Cta4p] (Mus musculus) PubMed

 9269.

purification and characterization of phenol monooxygenase; enzyme requires NADH and FAD as cofactors, catalyses hydroxylation of a wide range of monocyclic phenols, aromatic acids and dihydroxylated derivatives of benzene except for catechol (Mus musculus) PubMed

 9270.

miR-BHRF1-1 is involved in TPA-induced accumulation of EBV lytic proteins and viral copies in late lytic cycle (miR-BHRF1-1). (Mus musculus) PubMed

 9271.

FadA binds vascular endothelial cadherin and alters endothelial integrity. [FadA] (Mus musculus) PubMed

 9272.

The amino-terminal signal peptide of Vfr protein negatively influences RopB-dependent SpeB expression and attenuates virulence.[Vfr, RopB, SpeB] (Mus musculus) PubMed

 9273.

The 2.0 A resolution structure of Zn(II)-bound AdcR reveals a highly helical two-fold-symmetric dimer with two distinct metal-binding sites per protomer. [AdcR] (Mus musculus) PubMed

 9274.

In Cfr and RlmN, S-adenosylmethionine bound to the unique iron of the [4Fe-4S] cluster displays 2 reactivities; serves to methylate C338 or to generate the 5'-deoxyadenosyl 5'-radical, required for substrate-dependent methyl synthase activity.[Cfr] (Mus musculus) PubMed

 9275.

crystal structure of Cel5A resolved to 2.05 A [Cel5A] (Mus musculus) PubMed

 9276.

cloned the gene for CXCLC; results indicate that CXCLC attracts adjacent cells to the midline region, so as to ensure accurate lateral-medial directional tissue convergence during gastrulation and neurulation [CXCLC] (Mus musculus) PubMed

 9277.

In contrast, a deficiency of the Treponema denticola major outer sheath protein increased resistance to LL-37.[major outer sheath protein] (Mus musculus) PubMed

 9278.

This study has also shown significantly lower disease burden in Gambians infected with a mixture of cag-positive and cag-negative strains.[cagA] (Mus musculus) PubMed

 9279.

These results uncovered extensive connections between Hsp90 and (1) general transcription, (2) ribosome biogenesis and (3) GTP binding proteins.[Hsp90] (Mus musculus) PubMed

 9280.

the GAS surface adhesin Scl1 may have an important role in biofilm-associated pathogenicity.[sCL1] (Mus musculus) PubMed

 9281.

Spodoptera frugiperda (fall armyworm) larvae fed samples of both Mp708 and Tx601 Zea mays genotypes showed high transcript number of tps23, the gene responsible for the synthesis of (E)-beta-caryophyllene in maize.[terpene synthase 23] (Mus musculus) PubMed

 9282.

OsMGH3 was characterized by overexpression and knock-down analysis and a partial overlap in these phenotypes with that of mutants in OsMADS1 and OsMADS6, was shown.[OsMGH3, OsMADS1, OsMADS6] (Mus musculus) PubMed

 9283.

OsCYP96B4 might be involved in lipid metabolism and regulate cell elongation.[OsCYP96B4] (Mus musculus) PubMed

 9284.

FgVeA plays a critical role in a variety of cellular processes in F. graminearum.[FgVeA] (Mus musculus) PubMed

 9285.

Csc1p is required for the dephosphorylation of the septation initiation network scaffolding protein Cdc11p and is thereby required for the recruitment of Byr4p, a component of the GTPase-activating subunit for Spg1p, to the mitotic spindle pole bodies. (Mus musculus) PubMed

 9286.

C1d and primary ciliary dyskinesia protein 1(Pcdp1)coordinate the activity of specific dynein isoforms to control ciliary motility [C1d][primary ciliary dyskinesia protein 1] (Mus musculus) PubMed

 9287.

the first incidence of Rem2 isoforms in a species that are the result of gene duplication.[Rem2] (Mus musculus) PubMed

 9288.

An unprecedented subdomain in the ATP-grasp module of GshF was identified at the interface of the GshF dimer, which is poised to mediate intersubunit communication and allosteric regulation of enzymatic activity. [GshF protein] (Mus musculus) PubMed

 9289.

a model for an Hsp90-Tah1-Pih1 ternary complex [Hsp90][Tah1][Pih1] (Mus musculus) PubMed

 9290.

the early spliceosomal association of Bud31 [Bud31][Ycr063w] (Mus musculus) PubMed

 9291.

The charged linker, in addition to providing the flexibility necessary for Hsp90 domain rearrangements--likely its original purpose--has evolved in eukaryotes to serve as a rheostat for the Hsp90 chaperone machine.[HSP90] (Mus musculus) PubMed

 9292.

A rad53 mutation that destabilized the Asf1-Rad53 complex and increased the viability of rad9 and rad24 mutants in conditions of genotoxic stress, was identified.[Rad53, Asf1] (Mus musculus) PubMed

 9293.

The pc4 induced foliar necrosis and supported the viral long-distance movement. [pc4] (Mus musculus) PubMed

 9294.

changes within the active site of TfGH11 lead to significant differences compared with those of previously deposited Xyn11 structures via the introduction of three water-mediated hydrogen bonds when compared with the known xylanase structures [GH11] (Mus musculus) PubMed

 9295.

Mbs1 promoted production of melanin and capsule and thereby was required for full virulence of C. neoformans. [Mbs1] (Mus musculus) PubMed

 9296.

Candida albicans cells lacking the SUR7 gene were more susceptible to attack by macrophages than cells with the gene and showed greatly reduced virulence in a mouse model of systemic infection.[SUR7] (Mus musculus) PubMed

 9297.

crystal of orotate phosphoribosyltransferase exhibited tetragonal symmetry, belonging to space group P4(1) or P4(3), with unit-cell parameters a = b = 49.15, c = 226.94 A [orotate phosphoribosyltransferase ] (Mus musculus) PubMed

 9298.

hese results provide the first example of involvement of the protein N-terminal acetyltransferase in the circadian rhythm.[Nat3] (Mus musculus) PubMed

 9299.

Cloning, sequencing and analysis of IL-6Ralpha and gp130 in rainbow trout and comparision with other predicted fish homologues (IL-6Ralpha and glycoprotein-130). (Mus musculus) PubMed

 9300.

These results demonstrate that Toxoplasma gondii serine protease inhibitor 1 influences both parasite virulence and bradyzoite differentiation, presumably by inhibiting parasite and/or host serine proteases.[serine protease inhibitor 1] (Mus musculus) PubMed

 9301.

The bleaching signal transduction pathway via NblS is regulated by RpaB and that SrrA is partially involved.[Nbls, RpaB, SrrA] (Mus musculus) PubMed

 9302.

The present results of this study suggest that sulfadoxine/pyrimethamine (as a DHFR and DHPS inhibitors) could be effective in treatment against the erythrocytic stages of vivax malaria in Iran. [dhfr, dhps] (Mus musculus) PubMed

 9303.

characterization of a novel recessive gene [HTD3] (Mus musculus) PubMed

 9304.

The MRP1 gene of Drosophila virilis contains an additional intron, intron Z, which is absent in Drosophila melanogaster. [MRP1] (Mus musculus) PubMed

 9305.

Soluble X. laevis GILT was inserted into a pET28a vector and expressed in BL21 cells as a His-tag fusion enzyme. After purification, XlsGILT catalyzed the reduction of the interchain disulfide bonds intact IgG. [GILT protein, Xenopus] (Mus musculus) PubMed

 9306.

A novel two-component system(PixA-NixB-NixC) of photoresponse is involved in the phototactic regulation.[PixA, NixB, NixC] (Mus musculus) PubMed

 9307.

AKR4C14 is a rice aldo-keto reductase and highly expressed in leaf sheets and stems.[AKR4C14] (Mus musculus) PubMed

 9308.

Inactivation ppk gene resulted in producing more antibiotics and less ATP. [ppk] (Mus musculus) PubMed

 9309.

MnSODs from S. cerevisiae mitochondria and C. albicans cytosol both exhibit higher efficiencies of O2- dismutation at high [O2-] than do human and bacterial MnSODs. [MnSOD] (Mus musculus) PubMed

 9310.

For KRTAP8-1, five unique banding patterns were detected in an amplicon that spanned the entire coding region[KAP8-1] (Mus musculus) PubMed

 9311.

ZmASR1-dependent regulation of branched-chain amino acids metabolites might contribute to regulate leaf growth, resulting in improvement in kernel yield [ASR1] (Mus musculus) PubMed

 9312.

MnSODs from S. cerevisiae mitochondria and C. albicans cytosol both exhibit higher efficiencies of O2- dismutation at high [O2-] than do human and bacterial MnSODs. [MnSOD] (Mus musculus) PubMed

 9313.

the two domains of Rtt106 are involved in a combinatorial recognition of H3-H4; the Rtt106-(H3-H4)(2) interaction is important for gene silencing and the DNA damage response [Rtt106] (Mus musculus) PubMed

 9314.

binding of NS1 to hPAF1C depends on the NS1 histone mimic and results in suppression of hPAF1C-mediated transcriptional elongation [NS1] (Mus musculus) PubMed

 9315.

These findings demonstrate a role for miR-134 in translation-dependent guidance of nerve growth cones.[miR-134] (Mus musculus) PubMed

 9316.

Features of Ulp1 that are required for substrate targeting, were investigated.[Ulp1] (Mus musculus) PubMed

 9317.

study reports the discovery of a novel superantigen staphylococcal enterotoxin-like toxin X encoded in the core genome of 95% of phylogenetically diverse S. aureus strains from human and animal infections. [SElX] (Mus musculus) PubMed

 9318.

AmyR regulates the expression of some of the Aspergillus niger genes encoding alpha- and beta-glucosidases, alpha- and beta- galactosidases, as well as genes encoding alpha-amlyases and glucoamylases.[AmyR] (Mus musculus) PubMed

 9319.

Our data suggest a role of glial DEG/ENaC channel ACD-1 in supporting neuronal activity. ACD-1 (Mus musculus) PubMed

 9320.

Srs2 carboxy-terminal domain harbours tandem receptor motifs that interact independently with PCNA and SUMO and that both motifs are required to recognize SUMO-PCNA specifically [Srs2, Pol30, Smt3] (Mus musculus) PubMed

 9321.

All the techniques yield evidence that TrpG8 and TyrCD1 can form strong H bonds with fluoride, whereas TyrB10 plays only a minor role in the stabilization of the ligand.[truncated hemoglobin] (Mus musculus) PubMed

 9322.

During growth on vanillin or vanillate, vanA was highly upregulated while vdh was not.[vanA & vdh] (Mus musculus) PubMed

 9323.

Rab5a is required for the intracellular transport of proglutelins from the Golgi to the protein storage vacuole in rice endosperm also in the maintenance of the general structural organization of the endomembrane system in developing rice seeds.[RAB5a] (Mus musculus) PubMed

 9324.

crystal structure of Staphylococcus aureus alanine racemase (Alr(Sas)), the sequence of which corresponds to that from the highly antibiotic-resistant Mu50 strain, has been solved to 2.15 A resolution[alanine racemase ] (Mus musculus) PubMed

 9325.

these motions may facilitate structural rearrangements of the active site that allow NADH oxidase to accept both FMN and FAD as cofactors. (Mus musculus) PubMed

 9326.

The low-abundance replication proteins Sld3, Sld7, and Cdc45 form a complex and associate with the early-firing origins in G1 phase in a manner that depends on Dbf4-dependent kinase (DDK), which is essential for the initiation of DNA replication.[Sld7p] (Mus musculus) PubMed

 9327.

phyC works cooperatively with phyA in transient gene expression after red light pulse [phyA; phyC] (Mus musculus) PubMed

 9328.

Prenatal testosterone exposure is associated with changes in AMH expression in preantral and antral follicles in adult ovaries, similar to findings in women with polycystic ovary syndrome. (Mus musculus) PubMed

 9329.

The present investigation unravels the possibility that RepB-like proteins and their binding sites represent ancient DNA-protein interaction modules.[RepB] (Mus musculus) PubMed

 9330.

the linker is likely a key contributor to Rep68 and Rep78 DNA-dependent oligomerization. [Rep68, Rep78] (Mus musculus) PubMed

 9331.

Mnt1 and Mnt2 are mannosyltransferases adding the fourth and fifth mannose residue to the O-mannans in C. albicans.[Mnt1][Mnt2] Mnt5 only recognized alpha-methylmannoside as acceptor, adding the second mannose residues to the N-glycan outer chain.[Mnt5] (Mus musculus) PubMed

 9332.

global changes with regard to enzyme function are discussed (Mus musculus) PubMed

 9333.

study describes for the first time the emergence of an mecA-negative Staphylococcus lugdunensis strain with a modified PBP1A/1B that expresses resistance to all beta-lactams. [PBP1A/1B] (Mus musculus) PubMed

 9334.

This work examines the interaction between canine plasminogen (dPgn) and Streptococcus pyogenes enolase (Str enolase).[Enolase] (Mus musculus) PubMed

 9335.

surface expression of non-functional PfEMP1 in D10 strongly indicating that genes other than clag9 deleted from chromosome 9 are involved in this virulence process [clag9][PfEMP1] (Mus musculus) PubMed

 9336.

Isolation and characterization of loss-of-function mutants of auxin efflux transporter MtPIN10 of a legume species, Medicago truncatula, are described.[MtPIN10] (Mus musculus) PubMed

 9337.

AKR1 molecules are S-acylated at locations other than the DHHC cysteine, increasing the abundance of AKR1 in the cell. (Mus musculus) PubMed

 9338.

A fatty acid desaturase gene TaFAD was then confirmed by virus induced gene silencing (VIGS) to be required for the powdery mildew resistance.[TaFAD] (Mus musculus) PubMed

 9339.

MTP1 is a bivalent cation transporter localized in the cell membrane, which is necessary for efficient translocation of Zn, Cd and other heavy metals, and maintain ion homeostasis in plant.[MTP1] (Mus musculus) PubMed

 9340.

Antibodies against variant surface antigens, PfEMP1 and RIFIN as well as MSP3 and GLURP, are acquired during a single short low density P. falciparum infection in non-immune individuals.[PfEMP1, RIFIN, MSP3, GLURP] (Mus musculus) PubMed

 9341.

Both the known and the novel Smqnr genes were discovered in both quinolone non-sensitive and sensitive isolates with similar frequency, suggesting that the Smqnr gene makes little contribution to quinolone resistance in this organism.[Smqnr] (Mus musculus) PubMed

 9342.

During both mitosis and meiosis, OsSGO1 is recruited from nucleoli onto centromeres at the onset of prophase. Centromeric localization of OsSGO1 depends on OsAM1. [OsSGO1 and OsAM1] (Mus musculus) PubMed

 9343.

Overexpression of DTH3 causes early flowering in callus. Edh1 was up-regulated by DTH3 in both long day and short day conditions. [DTH3; Edh1] (Mus musculus) PubMed

 9344.

Mutantion of cagI caused a reduction in the degree of CagA translocation. [cagI] (Mus musculus) PubMed

 9345.

OsERF3 regulates transcript levels of two MAPKs and two WRKYs, and mediates herbivore-induced JA, SA, ethylene and H2O2 biosynthesis. [OsERF3] (Mus musculus) PubMed

 9346.

amino acid polymorphisms within the Fn-binding repeats of FnBPA explain, at least partially, the statistically (p < 0.05) longer bond lifetime for isolates associated with an infected cardiovascular device.[FnBPA and FnBPB] (Mus musculus) PubMed

 9347.

these data suggest that TcRjl might play a role in the control of the parasite growth and differentiation.[TcRj1] (Mus musculus) PubMed

 9348.

Down-regulation of UAM1 reduces UDP-arabinopyranose activity and Arabinofuranose content in cell walls. [OsUAM1/UDP-arabinopyranose mutase] (Mus musculus) PubMed

 9349.

Glucagon-like peptide-1 receptor (GLP-1R) is expressed in guinea pig submucosal neurons. Activation leads to a decrease in neurally evoked chloride secretion by suppressing ACh release at neuroepithelial junctions in the enteric neural networks.(GLP-1R) (Mus musculus) PubMed

 9350.

The authors conclude that Atl is a major autolysin of Streptococcus suis HA9801: it takes part in cell autolysis, separation of daughter cells, biofilm formation, fibronectin-binding activity, cell adhesion, and pathogenesis.[Atl] (Mus musculus) PubMed

 9351.

Taken together, authors have identified a novel regulatory link between the VicRK and ComDE systems to modulate bacteriocin production and cell viability of Streptococcus mutans.[VicR & VicK] (Mus musculus) PubMed

 9352.

Based on this functional characterisation and high degree of sequence conservation with other fungal GATA factors, Penicillium marneffei areA represents an orthologue of Aspergillus nidulans areA and Neurospora crassa NIT2.[areA] (Mus musculus) PubMed

 9353.

Taken together with its increasing expression along the tonotopic axis, these data suggest that CDK5 likely plays a critical role in electrical tuning and surface expression of Slo in hair cells. (Mus musculus) PubMed

 9354.

Infection with hrgA-positive strain was not frequent among patients with gastric cancer. Presence of hrgA gene would not be a useful marker to predict clinical outcome of patients infected with H. pylori in this series of Japanese patients. (Mus musculus) PubMed

 9355.

These newly identified domains are composed of extended-length (114 A in IpaB and 71 A in SipB) coiled-coil motifs that display a high degree of structural homology to one another despite the fact that they share only 21% sequence identity.[IpaB] (Mus musculus) PubMed

 9356.

Molecular dynamics simulations indicate that the extracellular vestibule of NorM invariably loses its characteristic V shape and is reduced to a narrow permeation pathway lined by polar residues that can act as a specific pore for small cation transport. (Mus musculus) PubMed

 9357.

Reduced aeration affects the expression of the NorB efflux pump of S. aureus by posttranslational modification of MgrA. [NorB, MgrA] (Mus musculus) PubMed

 9358.

DeltacpsA strain showed significant attenuation in a zebrafish infection model. [CpsA] (Mus musculus) PubMed

 9359.

findings highlight not only the structural integrity of the pseudogene-encoded enzyme but also the necessity of obtaining an auxiliary tRNA-binding domain for functioning of a yeast tRNA synthetase (GlyRD2) (Mus musculus) PubMed

 9360.

Cultivation with glucose or ethanol as carbon substrate revealed that Adh1 was the only alcohol dehydrogenase capable of efficiently catalysing the reduction of acetaldehyde to ethanol.[Adh1] (Mus musculus) PubMed

 9361.

This study showed that in yeast, Sir2 activation prevents programmed cell death induced by the sustained activation of the stress activated protein kinase, Hog1, the yeast homologue of the p38 SAPK.[Sir2] (Mus musculus) PubMed

 9362.

We observed that wild-type KaiC (wt-KaiC) exhibits an ATP synthase activity that is significantly reduced in the T432A/S431A mutant. (Mus musculus) PubMed

 9363.

These observations, together with the co-purification of Hsc70 with Pepino mosaic virus virions further support the notion of a Pepino mosaic virus capsid protein/Hsc70 interaction during virus infection.[capsid protein] (Mus musculus) PubMed

 9364.

The deletion of CLC1 in JEC21 resulted in a mutant hypersensitive to cyclosporine A, an inhibitor of calcineurin. (Mus musculus) PubMed

 9365.

OsFRDL4 is an Al-induced citrate transporter localized at the plasma membrane of rice root cells and is one of the components of high Al tolerance in rice [OsFRDL4 (Os01g0919100)] (Mus musculus) PubMed

 9366.

Our results suggest that NUS1 is involved in the regulation of chloroplast RNA metabolism and promotes the establishment of the plastid genetic system during early chloroplast development under cold stress conditions. [NUS1] (Mus musculus) PubMed

 9367.

Dual targeting of Gnd1 is directed by alternative splicing resulting in two Gnd1 isoforms, one without targeting signals localized to the cytosol and one with a peroxisomal targeting signal targeted to peroxisomes.[Gnd1] (Mus musculus) PubMed

 9368.

PfGECO, encodes a predicted type IV heat shock protein 40 that we show is expressed in gametocyte stages I to IV and is exported to the RBC cytoplasm [GECO] (Mus musculus) PubMed

 9369.

the high prevalence of in-frame oipA gene strains (81%), associated with peptic ulcers and cagA(+), vacA s1, m1, m2, and, importantly, i1 genotypes, indicates a strong synergistic activity of H. pylori virulence factors [oipA] (Mus musculus) PubMed

 9370.

The N-terminal hydrophobic segment of FtsY forms a transmembrane structure to stabilize its membrane localization. [FtsY] (Mus musculus) PubMed

 9371.

Chromatin immunoprecipitation assays showed that Ino2p:Ino4p bind the PHO5 promoter and that this binding is dependent on Pho4p binding.[Ino2p, Ino4p, PHO5] (Mus musculus) PubMed

 9372.

These results indicate that Tomato yellow leaf curl China virus V2 is an RNA silencing suppressor, possibly through sequestering siRNA molecules.[V2] (Mus musculus) PubMed

 9373.

TSP2-1 was required for laccase repression by glucose in the basidiomycete Cryptococcus neoformans. TSP2-1 encodes a Tsp2-type tetraspanin. [TSP2-1] (Mus musculus) PubMed

 9374.

TaST can enhance the salt tolerance of transgenic Arabidopsis plants.[TaST] (Mus musculus) PubMed

 9375.

Cys residues in the CXXC motif of mcsA are involved in metal binding and protein interaction. [mcsA] (Mus musculus) PubMed

 9376.

The rice Ubiquitin1 (Ubi1) promoter was tested to evaluate its capacity to express the heterologous gusA gene encoding beta-glucuronidase in transgenic rice.[Ubi1] (Mus musculus) PubMed

 9377.

OsDUR3 is an active urea transporter that plays a significant role in effective urea acquisition and utilisation in rice.[OsDUR3] (Mus musculus) PubMed

 9378.

The influence of the SUB1A gene on dynamic changes in the metabolome during complete submergence provides new insights into the functional roles of a single gene in invoking a quiescence strategy (Mus musculus) PubMed

 9379.

results show that C. albicans Pph3 and Psy2 have important roles in mediating genotoxin-induced filamentous growth and regulating Rad53 dephosphorylation.[Pph3; Psy2] (Mus musculus) PubMed

 9380.

GdaA purified from an Aspergillus oryzae gdaA-overexpressing strain exhibited high D-stereospecificity and efficiently released N-terminal glycine and D-alanine of substrates in a highly specific manner.[gdaA] (Mus musculus) PubMed

 9381.

findings show that TgIF2K-D is a GCN2-like eIF2alpha kinase; TgIF2K-D was shown to enhance the viability of parasites during times when they are deprived of their host cells [TgIF2K-D] (Mus musculus) PubMed

 9382.

OsDREB2A expression was found to be markedly induced by drought and ABA treatment. The results indicate that the induced over-expression of OsDREB2A driven by the 4ABRC promoter in engineered rice plants may protect cells during stress. {OsDREB2A} (Mus musculus) PubMed

 9383.

optical and electrophysiological properties led to a model predicting receptor function that is based on stoichiometry and position of beta2 subunits within the alpha7beta2 nAChRs[chrna7] (Mus musculus) PubMed

 9384.

JAG2 is a key regulator of the timely and ordered generation of two of the defining cell types in the spinal cord.[jagged2] (Mus musculus) PubMed

 9385.

Inactivation of PldD inhibited activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2), indicating that Helicobacter pylori hemolytic phospholipases also harbor MAPK-activating properties.[PldD] (Mus musculus) PubMed

 9386.

The gp21 C-terminal region thus plays a central role in two early key events that commit the virus to deliver its genome into host cells: phage attachment and phage DNA ejection.[gp21] (Mus musculus) PubMed

 9387.

With the loss of nox, the activities of oxygen stress response enzymes such as superoxide dismutase and glutathione oxidoreductase were elevated compared to those in controls, resulting in a greater adaptation to oxygen stress.[nox] (Mus musculus) PubMed

 9388.

A. nidulans Wsc proteins have a different sensing spectrum and downstream signaling pathway than those in the yeast Saccharomyces cerevisiae and they play an important role in CWI under hypo-osmotic and acidic pH conditions. [WscA and WscB] (Mus musculus) PubMed

 9389.

The OsCYP20-2 gene may be a candidate for enhancing multiple abiotic stress tolerance. [OsCYP20-2] (Mus musculus) PubMed

 9390.

Cck1 regulates the phosphorylation of both Mpk1 and Hog1 mitogen-activated protein kinases (MAPKs), demonstrating that Cck1 regulates cell integrity via the Mpk1 pathway and regulates cell adaptation to stresses via the Hog1 pathway. [CCK1] (Mus musculus) PubMed

 9391.

Hydroxyurea toxicity can be suppressed by deletion of the gene encoding Brh2, the BRCA2 orthologue that serves to regulate homologous recombination by mediating Rad51 filament formation on single-stranded DNA.[Brh2] (Mus musculus) PubMed

 9392.

Results demonstrated that porphobilinogen deaminase (PBG-D)is a novel NO-tolerant protein through which Aspergillus nidulans increases protoheme synthesis and reactive nitrogen species tolerance. [porphobilinogen deaminase (PBG-D)] (Mus musculus) PubMed

 9393.

ToxR assist V. alginolyticus to colonize on the surface of the fish intestine. [ToxR] (Mus musculus) PubMed

 9394.

Rot and the Agr system in S. aureus NCTC8325 can affect the bacterial binding ability to human fibrinogen (Fg) under different bacterial growth phases through regulating clfB transcription. [Rot, Agr] (Mus musculus) PubMed

 9395.

conservation of autoregulatory infrastructure across the IpaH enzyme family [IpaH] (Mus musculus) PubMed

 9396.

Individually weak dispersed Sic1 phospho sites engage Cdc4 in a dynamic equilibrium. The multisite nature of this interaction confers cooperative dependence on kinase activity for Sic1 recognition & ubiquitination at equilibrium. Sic1. Cdc4. (Mus musculus) PubMed

 9397.

slow cleavage of the NS4B5A boundary is important and identify a previously unrecognized role for NS4B5A-containing precursors requiring them to exist for a minimum finite period of time [NS4B][NS5A] (Mus musculus) PubMed

 9398.

OsbZIP39 may be directly involved in the regulation of several endoplasmic reticulum stress response genes.[OsbZIP39] (Mus musculus) PubMed

 9399.

EGCrP1 controls the quality of GlcCer by eliminating immature GlcCer incorrectly generated in C. neoformans [EGCrP1] (Mus musculus) PubMed

 9400.

new insight into the enigmatic specificity of Hsp104-mediated curing of yeast prions [PSI][Hsp104] (Mus musculus) PubMed

 9401.

a mechanistic link between the Dsc E3 ligase complex and the proteasome in SREBP cleavage [SREBP][Cdc48]Dsc5] (Mus musculus) PubMed

 9402.

Targeting of MtPT4 to the periarbuscular membrane, was investigated.[MtPT4] (Mus musculus) PubMed

 9403.

The loss of hydrophobicity and the other developmental changes in the laeA deletion mutants could affect the ability of the fungus to produce aflatoxins.[laeA] (Mus musculus) PubMed

 9404.

these data provide evidence that S. aureus lipase plays important roles in the pathogenesis of S. aureus. [lipase] (Mus musculus) PubMed

 9405.

IAA11 mutant strictly blocks the initiation of lateral root primordia, but it does not affect crown root development. [IAA11] (Mus musculus) PubMed

 9406.

OsCCS52A is involved in maintaining normal seed size formation by mediating the exit from mitotic cell division to enter the endoreduplication cycles in rice endosperm. [CCS52A] (Mus musculus) PubMed

 9407.

crystals of indole prenyltransferase belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 84.4, b = 157.1, c = 161.8 A, alpha = beta = gamma = 90.0 degrees [ indole prenyltransferase ] (Mus musculus) PubMed

 9408.

Molecular dynamics simulations successfully capture the closed to open allosteric switching in DNA bound CzrA on Zn(II) binding. [CzrA] (Mus musculus) PubMed

 9409.

a novel, functional interaction between TFIIB and Ssl2 that affects start site selection and gene looping [Ssl2][TFIIB] (Mus musculus) PubMed

 9410.

the metal arrangement of cofactor in ribonucleotide reductase R2c [ribonucleotide reductase R2c] (Mus musculus) PubMed

 9411.

crystals of native and NAD(+)-complexed SSADH diffracted to resolutions of 1.6 and 1.7 A, respectively, using a synchrotron-radiation source[SSADH] (Mus musculus) PubMed

 9412.

ScACR3 expression significantly reduced As accumulation in rice straws and grains.[ScAcr3] (Mus musculus) PubMed

 9413.

The present study demonstrates that the NS1 protein and the polymerase complex (PB1, PB2 and PA) of the highly pathogenic H5N1 virus act in concert to antagonize chicken type I IFN secretion in HD-11 cells.[NS1, PB1, PB2 and PA] (Mus musculus) PubMed

 9414.

SEN1 is essential for nitrogen fixation activity and symbiosome/bacteroid differentiation in legume nodules.[SEN1] (Mus musculus) PubMed

 9415.

OsHMA2 is a major transporter of Zn and Cd from roots to shoots.[OsHMA2] (Mus musculus) PubMed

 9416.

data indicate migration inhibitory factor is important for liver-stage development of P. yoelii, during which it is likely to play an intrinsic role in parasite development rather than modulating host immune responses to infection. [MIF] (Mus musculus) PubMed

 9417.

HP1a and HP1b may play different roles in heterochromatin formation in holocentric silkworm chromosomes. [HP1a, Hp1b] (Mus musculus) PubMed

 9418.

CgAcr3-1 is an antiporter that catalyzes arsenite-proton exchange with residues Cys129 and Glu305 involved in efflux [Acr3-1] (Mus musculus) PubMed

 9419.

RLS1 with NB-ARM domains is involved in chloroplast degradation during leaf senescence. [RLS1] (Mus musculus) PubMed

 9420.

Report CLMP knockdown in zebrafish embryos as animal model for congenital short bowel syndrome. (Mus musculus) PubMed

 9421.

These results indicated that tyrosine phosphorylation of VP40 is important for triggering the recruitment of nucleocapsids to the viral envelope.[VP40] (Mus musculus) PubMed

 9422.

OsALDH7 is involved in the production of oryzamutaic acid A. [ALDH7] (Mus musculus) PubMed

 9423.

Man5A belongs to the glycoside hydrolase family 5 and displays the highest activity at pH 3.5 and 70 degrees C. [Man5A] (Mus musculus) PubMed

 9424.

Subsequent knockout and complementation studies provided solid evidence that the endogenous LacY was responsible for the transport of cellobiose.[LacY] (Mus musculus) PubMed

 9425.

Both NRRa and NRRb played negative regulatory roles in rice root growth. [NRRa, NRRb] (Mus musculus) PubMed

 9426.

bZIP72 expression was up-regulated by high-salinity treatment in maize. [bZIP72] (Mus musculus) PubMed

 9427.

MtLYM2, but not MtLYM1, showed specific binding to biotinylated N-acetylchitooctaose in a manner similar to CEBiP. We postulate that LYM2-type proteins likely function in the perception of chitin-related molecules. [MtLYM2] (Mus musculus) PubMed

 9428.

substrate specificity of Desulfitobacterium hafnience PylRS [PylRS] (Mus musculus) PubMed

 9429.

ILA1 (increased leaf angle1) is a functional kinase with Ser/Thr kinase activity. [ILA1] (Mus musculus) PubMed

 9430.

on/off associated histone modifications of individual rif genes [rif] (Mus musculus) PubMed

 9431.

These data confirm CCL5 is an essential factor for optimal pneumococcal adaptive immunity and show CD4(+) T cell responses to PspA(199-246) are largely resistant to CCL5 deficiency.[PspA] (Mus musculus) PubMed

 9432.

TbPIF8 is essential for cell viability and is important for maintenance of kinetoplast DNA. [PIF8] (Mus musculus) PubMed

 9433.

PFR functions as a biomechanical spring that may store and transmit energy derived from axonemal beating [PFR] (Mus musculus) PubMed

 9434.

These data indicate that, in Trichomonas vaginalis, phosphorylations and glycosylations are necessary to obtain the mature TveIF-5A.[eIF-5A] (Mus musculus) PubMed

 9435.

gene coding for a major extracellular chitosanase was isolated from Aspergillus oryzae IAM2660 [chitosanase] (Mus musculus) PubMed

 9436.

The LEE1 operon is driven by two promoters separated by 10 bp, LEE1 P1A (+1) and LEE1 P1B (+10). The p1B promoter has multiple transcription start sites. [LEE1] (Mus musculus) PubMed

 9437.

Over-expression of Usb1 can compensate for defects in the biogenesis of the respiratory complexes. [Usb1p] (Mus musculus) PubMed

 9438.

SNB and OsIDS1 redundantly function in spikelet meristem transition and determinacy. They also regulate floral organ identity, and control the duration of inflorescence and branch meristems. [SNB; IDS1] (Mus musculus) PubMed

 9439.

we describe the identification, in the genome of S. aureus strain COL, of two co-transcribed genes, murT and gatD, which are responsible for peptidoglycan amidation. (Mus musculus) PubMed

 9440.

OsDCL4 preferentially affects 21-nucleotide siRNA biogenesis in panicles. The 24-nucleotide phased small RNAs are processed by OsDCL3b. OsDCL1-dependent small RNAs may trigger 21- and 24-nucleotide phased small RNA initiation. [DCL1; DCL3b; DCL4] (Mus musculus) PubMed

 9441.

this study identifies CDC-24 as essential regulator for RAC and CDC-42 that have common and distinct functions during polarity establishment and maintenance of cell polarity in N. crassa.[RAC] (Mus musculus) PubMed

 9442.

Expression of the RAA4 gene restores trans-splicing and photosynthesis in the raa4 mutant. [Raa4] (Mus musculus) PubMed

 9443.

(SVH-1) The Caenorhabditis elegans SVH-1 growth factor and its receptor, SVH-2 tyrosine kinase, regulate axon regeneration. (Mus musculus) PubMed

 9444.

Caenorhabditis elegans flamingo cadherin fmi-1 regulates GABAergic neuronal development (Mus musculus) PubMed

 9445.

role of frataxin in Fe-S assembly [CyaY] (Mus musculus) PubMed

 9446.

crystal structure of PI-PLC at pH 4.6 and pH 7.5 [PI-PLC] (Mus musculus) PubMed

 9447.

the biological function of LmP is to act as a cytochrome c peroxidase [cytochrome c peroxidase] (Mus musculus) PubMed

 9448.

insight into the unusual control mechanisms of actin dynamics [PRF]FRM1][FRM2] (Mus musculus) PubMed

 9449.

the phosphorylation status of CNP-1 plays an important role in regulation of refed stimulating behaviors after starvation and attraction to amino acid, which provides valuable nutritious information.[CNP-1] (Mus musculus) PubMed

 9450.

Altogether the results show that MglA is required for normal adaptation of Francisella tularensis to oxidative stress and oxygen-rich environments.[MglA] (Mus musculus) PubMed

 9451.

IFNalpha-induced PLSCR1 associates with the cytoskeleton after exposure to alpha-toxin, and cellular depletion of PLSCR1 negates IFN-induced protection from alpha-toxin.[alpha-toxin] (Mus musculus) PubMed

 9452.

Expression of mouse mammary tumor virus Gag requires nuclear interactions involving the viral Rem protein, its cognate binding target the RmRE, and surprisingly, both a splice donor and acceptor sequence.[Rem] (Mus musculus) PubMed

 9453.

PfSET10 is a histone 3 lysine 4 methyltransferase required to maintain the active var gene in a poised state during division for reactivation in daughter parasites, and as such is required for Plasmodium falciparum antigenic variation.[PfSET10] (Mus musculus) PubMed

 9454.

The ability to bind to dNTP and the involvement of a Theorell-Chance mechanism are key aspects of the strong nucleotide-binding and efficient gap-filling activities of DNA Polymerase X.[DNA Polymerase X; ttPolX] (Mus musculus) PubMed

 9455.

SpoVG is a sigmaB-dependent element that fine-tunes the expression of esxA by counteracting the sigmaB-induced repressing activity of the transcriptional regulator SarA and activates esxA transcription.[esxA, SpoVG] (Mus musculus) PubMed

 9456.

Not4 is required for appropriate association of the Not5 subunit of the Ccr4-Not complex with polysomes and for ubiquitination of Rps7A. (Mus musculus) PubMed

 9457.

zebrafish Mms2 and Ubc13 form a stable complex, which is required for p53-mediated DNA-damage response [Mms2] (Mus musculus) PubMed

 9458.

OsDIS1 interacts with a serine/threonine protein kinase OsNek6 and promotes its degradation via the 26S proteasome dependent pathway to negatively regulate drought stress tolerance. [DIS1] (Mus musculus) PubMed

 9459.

MtPIN4, MtPIN5 and MtPIN10/SLM1 may have limited redundant functions in the development of M. truncatula. [PIN4; PIN5; PIN10] (Mus musculus) PubMed

 9460.

crystal structure of BEI at a resolution of 1.9 A by molecular replacement [BEI] (Mus musculus) PubMed

 9461.

The authors report here the identification of a new acyl-CoA:diacylglycerol acyltransferase gene, DGA2, homologous to the ARE genes of Saccharomyces cerevisiae.[DGA2] (Mus musculus) PubMed

 9462.

AMA1 and RON4 are important for merozoite invasion of erythrocytes,but only RON4 is required for sporozoite invasion of hepatocytes. [Ron4] (Mus musculus) PubMed

 9463.

These results suggest that the Oryza sativa HSP26 protein plays an important role in the protection of photosystem II during heat and oxidative stress in vivo.[HSP26] (Mus musculus) PubMed

 9464.

Candida albicans cells were able to compensate for the increased levels of either Tpk1p or Tpk2p subunits with a corresponding elevation of Bcy1 protein levels and vice versa, implying a tightly regulated holoenzyme formation.[Tpk1p, Tpk2p, Bcy1] (Mus musculus) PubMed

 9465.

AMA1 is dispensable for normal RON4 ring and functional tight junction assembly but enhances tachyzoite apposition to the cell and internalization frequency. [Ron4] (Mus musculus) PubMed

 9466.

Using two-hybrid approach, we wshow that GraS interacts with both GraX and the VraG permease indicating an original five-component system involved in CAMP sensing and signal transduction to promote S. aureus resistance. [Gras, GraX, VraG] (Mus musculus) PubMed

 9467.

Using circular dichroism and two-hybrid analyses, we found that Atx1 can bind Cd(2+) specifically and that Cd(2+) binding to Atx1 affects the physical interaction between Atx1 and Ccc2.[Atx1, Ccc2] (Mus musculus) PubMed

 9468.

The authors use novel un-24(PA)het-6(OR) strains and het-6 deletion strains to demonstrate that nonallelic interactions occur between un-24 and het-6.[un-24 and het-6] (Mus musculus) PubMed

 9469.

These results confirm the direct regulatory role of RamR in the repression of ramA transcription and precisely define how an alteration of its binding site can give rise to an MDR phenotype. [RamR, RamA] (Mus musculus) PubMed

 9470.

The present study demonstrates that the yncD gene plays an important role in bacterial survival inside the host and is suitable for the construction of attenuated vaccine strains as a candidate target gene.[yncD] (Mus musculus) PubMed

 9471.

The hypersusceptibilities of the RDR6-suppressed plants were attributed not to enhanced insect infestation but to enhanced Rice stripe virus infection.[RDR6] (Mus musculus) PubMed

 9472.

Quality control C. jejuni ATCC33560 contains frameshift mutation in CmeR regulator. [CmerR] (Mus musculus) PubMed

 9473.

TbENF is a TbTFIIB-interacting protein and has a role in trypanosome gene transcription. [ENF, TFIIB] (Mus musculus) PubMed

 9474.

In conclusion, in the raft system, HPV8 E6 prevented late-terminal keratinocyte differentiation resulting in an accumulation of Filaggrin and pro-Caspase-14-positive cells in the absence of stratification.[E6] (Mus musculus) PubMed

 9475.

Penicillin production was decreased in the pcvA over-expressed strain suggesting that pcvA is involved in vesicle-vacuolar fusion participates in the penicillin biosynthesis in Penicillium chrysogenum.[pcvA] (Mus musculus) PubMed

 9476.

Ring-enlarged macrolactones instead of macrolactams can be generated by the amide synthase present in S. hygroscopicus. [amide synthase] (Mus musculus) PubMed

 9477.

Variable expression of aac(6')-Ib-cr gene are associated with changes in ciprofloxacin resistance levels. [aac(6')-Ib-cr] (Mus musculus) PubMed

 9478.

The minimal genetic changes in either walK or walR attenuated virulence, reduced biofilm formation, and led to consistent transcriptional changes that suggest an important role for this regulator in control of central metabolism [walK; walR] (Mus musculus) PubMed

 9479.

A nonsense mutation in the ATPase sensor domain of the FsrC protein is responsible for sensing and transducing the signal from the quorum-sensing molecule. [FsrC] (Mus musculus) PubMed

 9480.

The results indicated that the structure of the HIV gp41 fusion domain is plastic and depends critically on the lipid environment. [gp41 protein, HIV] (Mus musculus) PubMed

 9481.

the peak expression of MLH in both 3D7 and Dd2 strains of P. falciparum is mainly in the schizont stages of the intraerythrocytic development, where DNA replication is active [MLH] (Mus musculus) PubMed

 9482.

Deletion of Hep1 in a PH-1 background strongly influences expression of genes required for the production of aurofusarin and the main tricothecene metabolite DON.[Hep1] (Mus musculus) PubMed

 9483.

The numerical value of the open/closed free energy difference is only 1-2 k(B)T, much smaller than some of the prior estimates. [adenylate kinase] (Mus musculus) PubMed

 9484.

Tfb6 does not, however, dissociate Ssl2 from TFIIH in the context of a fully assembled transcription preinitiation complex.[Ssl2, Tfb6] (Mus musculus) PubMed

 9485.

essential roles for the histidine residues of E1 and E2 of HCV in the formation of a functional heterodimer and in regulating the threshold of fusion activation.[E2] (Mus musculus) PubMed

 9486.

Streptomyces coelicolor sRNA scr5239 inhibits dagA expression by direct base pairing to the coding region. [scr5239] (Mus musculus) PubMed

 9487.

The study presents the 2.9-A crystal structure of the heterodimeric ABC transporter TM287-TM288 (TM287/288) from Thermotoga maritima in its inward-facing state. [TM287-TM288] (Mus musculus) PubMed

 9488.

crystal structure of the 380-kDa motor domain of Dictyostelium discoideum cytoplasmic dynein at 2.8 A resolution (Mus musculus) PubMed

 9489.

A single amino acid in the active site was reported to determine the different product specificities of SbTPS1 and SbTPS2.(terpene synthase 1 (Mus musculus) PubMed

 9490.

The data indicate that allosteric effector 13(S)-hydroxyoctadeca-9(Z),11(E)-dienoic acid shifts the dynamic monomer-dimer equilibrium of 12/15-lipoxygenase favoring the formation of transient enzyme dimers. [12/15-lipoxygenase] (Mus musculus) PubMed

 9491.

TNPO3 binds to a surface of monomeric HIV-1 integrase that remains exposed after tetramerization.[Integrase] (Mus musculus) PubMed

 9492.

Interaction between the coiled-coil domain of rice blast resistance protein Pi36 and methyl-jasmonate (MeJA) was studied by fluorescence and UV-vis spectroscopic techniques.[Pi36] (Mus musculus) PubMed

 9493.

The authors show that StkP specifically phosphorylates in vivo the cell division protein DivIVA on threonine 201. (Mus musculus) PubMed

 9494.

Peptide deformylase 1 (PDF-1) is strongly activated by Cu(2+) and inhibited by Ni(2+). [PDF-1] (Mus musculus) PubMed

 9495.

CerS (ceramide synthase) activity is exclusively dependent on acyl-CoAs, with palmitoyl-CoA being preferred. [CerS] (Mus musculus) PubMed

 9496.

Reduced mitoferrin levels in C. elegans by RNA interference treatment causes pleiotropic phenotypes such as small body size, reduced fecundity, slow movement and increased sensitivity to paraquat.[mitoferrin] (Mus musculus) PubMed

 9497.

gamma-tubulin and SPD-5 limit microtubule polymerization within the centrosome core.[Gamma-tubulin] (Mus musculus) PubMed

 9498.

These results support and expand previous in vitro and in vivo work that demonstrated ligand-dependent species differences in AHR1 affinity.[AHR1] (Mus musculus) PubMed

 9499.

Recombinant Sbi bound to purified cytoplasmic membrane material in vitro and to purified lipoteichoic acid.[Sbi] (Mus musculus) PubMed

 9500.

The copper transporter Ctr1p serves as a molecular target of saxitoxin.[Ctr1] (Mus musculus) PubMed

 9501.

[MC159 protein] MC159 (viral FLIP)coimmunoprecipitates with IkappaB kinase (IKK) during molluscum contagiosum poxvirus infection. (Mus musculus) PubMed

 9502.

Ureaplasmas are capable of MBA phase variation in vitro; however, ureaplasmas undergo MBA size variation in vivo, to potentially prevent eradication by the immune response.[MBA] (Mus musculus) PubMed

 9503.

These results suggest a coupled control mechanism, whereby the same DIF-DimB signaling pathway that directly activates ecmB gene expression directly represses pspA gene expression. (Mus musculus) PubMed

 9504.

The phenotypes of OsmiR393-overexpressing rice may be caused through hyposensitivity to the auxin signal by reduced expression of two auxin receptor genes (OsTIR1 and OsAFB2). [OsTIR1, OsAFB2, OsmiR393] (Mus musculus) PubMed

 9505.

OsABC1-2, is expressed primarily in green tissues and encodes a protein localized in chloroplast envelope.[OsABC1-2] (Mus musculus) PubMed

 9506.

P34 and P37 interact in vitro with the 5S rRNA.[P34, P37] (Mus musculus) PubMed

 9507.

Rabbit actin forms thin cylindrical filaments about 100 microm in length, cyanobacterial actin polymers resemble a ribbon. Eukaryotic profilin is a specific actin monomer binding protein, cyanobacterial profilin decorates actin filaments.[Actin] (Mus musculus) PubMed

 9508.

Constitutive overexpression of EhMLBP protects trophozoites against heat shock and reduces protein aggregation. This protective function is lost in trophozoites that overexpress a mutated form of EhMLBP which is devoid of its heat shock domain. [MLBP] (Mus musculus) PubMed

 9509.

The authors report that lsoA (ORF1) encodes a toxin and lsoB (ORF2) an antitoxin.[lsoA, lsoB] (Mus musculus) PubMed

 9510.

The study reports a crystal structure of IpaD with deoxycholate bound and test the importance of the residues that make up the deoxycholate binding pocket on IpaD function. [IpaD] (Mus musculus) PubMed

 9511.

OGNT-2 glycosyl transferase is expressed differentially along the life cycle and is present in the Golgi apparatus and in reservosomes [TcOGNT-2 glycosyl transferase] (Mus musculus) PubMed

 9512.

In medaka, the two col2a1 genes show a closely correlated pattern of spatial and temporal expression. However, there were differences in both expression patterns in the pectoral fin. [Col2a1] (Mus musculus) PubMed

 9513.

DAF-16 and Delta9 desaturase genes promote cold tolerance in long-lived Caenorhabditis elegans age-1 mutant [delta-9 desaturase] (Mus musculus) PubMed

 9514.

These results suggest that basic residues within a dimerized FtsN(Cyto) protein interact directly with residues in subdomain 1c of FtsA.[FtsN; FtsA] (Mus musculus) PubMed

 9515.

These results suggest a previously unsuspected role for RNA secondary structure as a determinant of RNase E essentiality; the effects of mutation of the ATP-dependent RNA helicase DeaD were medium independent.[RNase E; deaD RNA helicase] (Mus musculus) PubMed

 9516.

relationship between cellular SO(4)(=) and transport inactivation (Mus musculus) PubMed

 9517.

ICP27 competes with some host cell transport receptors for binding, resulting in inhibition of those host transport pathways. [ICP27] (Mus musculus) PubMed

 9518.

M2-induced membrane curvature (Mus musculus) PubMed

 9519.

VP2 contains a nuclear localization signal that spans from amino acids 133 to 138; VP2 is a CRM1 independent protein during nuclear export and associates with mini-chromosome maintenance protein 3 (MCM3) in cells (Mus musculus) PubMed

 9520.

AREA and AREB together with the co-repressor NMRA negatively regulate arginine catabolism in response to nitrogen and carbon source.[AREB] (Mus musculus) PubMed

 9521.

T6SS of B. cenocepacia is responsible for pyrin-dependent caspase-1 and IL-1beta processing and release by human mononuclear phagocytes. T6SS. (Mus musculus) PubMed

 9522.

The Asp187 is responsible for transport activity instead of coupling-ion binding by constituting the translocation pathway of the ion and Gln190 provides a suppressing mutation site to regain PutP functional activity. (Na(+)/proline symporter) (Mus musculus) PubMed

 9523.

The recombinant Alg17C was found to preferentially act on oligoalginates with degrees of polymerization higher than 2 to produce the alginate monomer, 4-deoxy-L: -erythro-5-hexoseulose uronic acid.[Alg17C] (Mus musculus) PubMed

 9524.

a role for VAR2CSA in childhood malaria and implicate DBL2betaC2(PF11_0521) in protective immunity [PfEMP1][VAR2CSA] (Mus musculus) PubMed

 9525.

A novel hypothetical gene annotated as TGME49_010810 encodes 2 protein isoforms of 11.7 (Mus musculus) PubMed

 9526.

results suggested that HCV NS5A protein can enhance survivin transcription by increasing p53 degradation and stimulating NOS2A expression as well as NF-kappaB relocation to the nucleus. [NS5A] (Mus musculus) PubMed

 9527.

The autophagy proteins LGG-1 was sequentially recruited to internalized apoptotic Q cells in the phagocyte.(LGG-1 protein) (Mus musculus) PubMed

 9528.

FEZ1 operates as a kinesin adaptor for the transport of Stx, with cargo loading and unloading being regulated by protein kinases.[Unc-76, syntaxin-1] (Mus musculus) PubMed

 9529.

A model of DNA recognition by HpNikR is proposed in which Ni(II) coordination to specific sites in the metal-binding domain have a long-range effect on the flexibility of the DNA-binding domains.[NikR] (Mus musculus) PubMed

 9530.

The gamma-tubulin was stably integrated into MT nucleation sites and was further stabilized by tubulin binding.( gamma-tubulin ) (Mus musculus) PubMed

 9531.

model predicts a clutch-like mechanism that rapidly engages a treadmilling transcription factor into a stable binding state, or vice versa, to modulate transcription factor function (Mus musculus) PubMed

 9532.

CD4-bound conformation represents a "ground state" for the gp120 core.[gp120] (Mus musculus) PubMed

 9533.

A chloroplast-localized HAT protein, HCF107, is a sequence-specific RNA binding protein.[Hcf107] (Mus musculus) PubMed

 9534.

We report the determination and analysis of the crystal structure of Class II CPD photolyase (a UVR2 homolog) from Oryza sativa. [CPD2PHR] (Mus musculus) PubMed

 9535.

the rice CHD3 protein CHR729 that was required for many aspects of plant development can interact with dimethylated histone H3 lysine 4.[CHR729] (Mus musculus) PubMed

 9536.

StkP signals information about the cell-wall status to key cell-division proteins and in this way acts as a regulator of cell division.[StkP] (Mus musculus) PubMed

 9537.

Vid30 also has a role in the vacuole import and degradation pathway.[Vid30] (Mus musculus) PubMed

 9538.

ROP16, ROP18, and GRA15 are parasitic virulence factors that determine strain-specific accumulation of mGBP1 on the parasitophorous vacuole [ROP16, ROP18, and GRA15] (Mus musculus) PubMed

 9539.

The effect of human chorionic gonadotropin on the activities of cytochrome P-450 CYP1A1, cytochrome P-450 CYP2B1 and methoxyresorufin O-demethylase (MROD) was studied in intact male pigs of 2 breeds.[CYP2B1; MROD] (Mus musculus) PubMed

 9540.

The ability of both Col2.3-Cre and Col3.6-Cre to drive nonspecific loxP recombination in the brain and of leptin to force recombination in leptin-responsive P-Stat3-positive neurons, was investigated. (Mus musculus) PubMed

 9541.

The data suggested that blocking PC-PLC function significantly inhibited lipopolysaccharide-induced IL-8 and MCP-1 production. (Mus musculus) PubMed

 9542.

Xiaotan Sanjie Decoction XTSJD can decrease the protein expressions of IL-8 and its receptors CXCR1/CXCR2 in tumor xenografts and gastric tissue adjacent to the tumor. [IL8] (Mus musculus) PubMed

 9543.

CTCF binding promotes SCAANT1; loss of SCAANT1 derepressed ataxin-7 sense transcription in a cis-dependent fashion and was accompanied by chromatin remodeling. (Mus musculus) PubMed

 9544.

miR-584 contributes to the post-transcriptional expression of lactoferrin receptor during the perinatal period.[miR-584] (Mus musculus) PubMed

 9545.

a model of CagA-directed REG3gamma expression in gastric epithelial cells via activation of the IL-11/gp130/STAT3 pathway [CagA] (Mus musculus) PubMed

 9546.

SP-STP secreted from Streptococcus pyogenes is a pro-apoptotic protein. [SP-STP] (Mus musculus) PubMed

 9547.

A26 protein binds to A16 and G9 proteins and dissociates from mature virions at low pH. [A16, G9] (Mus musculus) PubMed

 9548.

Herpesvirus saimiri tegument protein specifically degraded the cellular ND10 component Sp100. [tegument protein] (Mus musculus) PubMed

 9549.

These results imply that lalA, a paralog of labA, is capable of affecting circadian gene expression and cell growth [lalA, labA]. (Mus musculus) PubMed

 9550.

a new mechanism used by CoVs in which CoV PLPs negatively regulate antiviral defenses by disrupting the STING-mediated IFN induction [PLP] (Mus musculus) PubMed

 9551.

The C-terminal tandem BRCT repeats of Rtt107 interaction with gammaH2A is functionally important during DNA repair. [gammaH2A] (Mus musculus) PubMed

 9552.

membrane tension pulls on S5-S6, expanding the core and opening the TRPY1 gate. [TRPY1] (Mus musculus) PubMed

 9553.

Naringinase was purified to homogeneity; naringinase was confirmed to metabolize naringin, to consist of 2 subunits (MW 65.5 kDa), and to exhibit relative stability. An optimized fermentation/biosynthetic process is described. [naringinase] (Mus musculus) PubMed

 9554.

Functional characterization of WRKY45 is reported.[WRKY45] (Mus musculus) PubMed

 9555.

Rab7 and the actin cytoskeleton participated in the mobilization of beta1EhFNR in fibronectin-stimulated trophozoites[beta1EhFNR] (Mus musculus) PubMed

 9556.

These data suggest that both the protease and chaperone activities of DegP are likely important for the impact on T3S via CpxP and CpxR.[DegP; CpxP; CpxR] (Mus musculus) PubMed

 9557.

Neutrophil extracellular traps NETs) produced by human cell lines infected with the Afa/Dr wild-type E. coli strain C1845 are described, and the effects of NETs on enterocyte-like cells are reported.[Afa/DR] (Mus musculus) PubMed

 9558.

This study found that PstS2, the periplasmic component of the Pst2 phosphate uptake system, was enriched in biofilms.[Pst2] (Mus musculus) PubMed

 9559.

The impacts of mutations in the two nuclease genes, nuc1 and nuc2, of Staphylococcus aureus, on the ability of the organism to form biofilms are reported.[nuc1; nuc2] (Mus musculus) PubMed

 9560.

ZmNIP2;4 transcripts was abundant in reproductive organs and roots and unaffected under nitrogen starvation. (ZmNIP2;4) (Mus musculus) PubMed

 9561.

Chitin deacetylase 2 (Cda2) is a GPI-anchored protein active in the plasma membrane and also noncovalently associated with the cell wall in a manner independent of both the GPI anchor and beta-1,6-glucan.[Cda2] (Mus musculus) PubMed

 9562.

UGM has several extra secondary and tertiary structural elements which are important for substrate recognition and oligomerization. [UGM] (Mus musculus) PubMed

 9563.

We provide evidence that Abp1 is the main F-actin-binding protein in this assay and is central for the interplay between DymA and MyoB during phagosome maturation. [3 genes, DymA, MyoB, and Abp1] (Mus musculus) PubMed

 9564.

A global analysis of the mRNAs that interact with the TbZFP3mRNP, revealing a role for this regulator in the developmental events associated with parasite transmission from the mammalian bloodstream form to tsetse midgut form (TbZFP3). (Mus musculus) PubMed

 9565.

The decrease in PECAM-1 expression in the lung was correlated with the increase in paraquat dosage in rabbits after acute paraquat poisoning. (Mus musculus) PubMed

 9566.

crystal structures of GPPMT in complex with GPP or the substrate analogue geranyl S-thiolodiphosphate (GSPP) along with S-adenosyl-L-homocysteine in the cofactor binding site, (GPPMT) (Mus musculus) PubMed

 9567.

The crystal structure of 2-methylisoborneol synthase (MIBS) from Streptomyces coelicolor A3(2) has been determined in complex with substrate analogues geranyl-S-thiolodiphosphate and 2-fluorogeranyl diphosphate at 1.80 and 1.95 A resolution, (MIBS) (Mus musculus) PubMed

 9568.

The minor envelope proteins GP2, GP3, GP4, and E together play a key role in the entry of arteriviruses into cultured cells. [E protein] (Mus musculus) PubMed

 9569.

charged amino acids within membrane spans are important for the transport mechanism of OsSUT1 as they are in lactose permease.(OsSUT1) (Mus musculus) PubMed

 9570.

TcyR was found to repress transcription of the tcyABC operon and regulates L-cystine uptake. [TcyR] (Mus musculus) PubMed

 9571.

The collapse of ER cisternae observed during ASFV infection is dependent on the viral envelope protein, J13Lp. (Mus musculus) PubMed

 9572.

crystal structure of the BGlu1 E386G glycosynthase with a-GlcF showed a stabilizing water molecule at the position of the nucleophile of apo BGlu1 beta-glucosidase[Os3BGlu7] (Mus musculus) PubMed

 9573.

study results show that the interaction between PARP10 and NS1 of H5N1 avian influenza virus can change cell cycle, and PARP10 can affect virus replication [H5N1 NS1] (Mus musculus) PubMed

 9574.

role of Tyr-435 in Vibrio harveyi chitinase A activity [chitinase A] (Mus musculus) PubMed

 9575.

Taken together, these findings demonstrate that YgfZ contributes to CNF1 secretion into outer-membrane vesicles in meningitis-causing Escherichia coli K1.[YgfZ, CNF1] (Mus musculus) PubMed

 9576.

Tarp colocalization with actin filaments is independent of the Tarp phosphorylation domain. [Tarp] (Mus musculus) PubMed

 9577.

the FCoV Nsp7:Nsp8 complex functions as a noncanonical RNA polymerase capable of synthesizing RNA of up to template length. (Mus musculus) PubMed

 9578.

novel type 2 20beta-HSDs in teleost fish are important enzymes in cortisol catabolism. (Mus musculus) PubMed

 9579.

Analysis of SopB GTPase binding domain in complex with Cdc42 shows that SopB structurally and functionally mimics a host guanine nucleotide dissociation inhibitor. (Mus musculus) PubMed

 9580.

This study showed that the variable subdomain of secA is dispensable for SecA function, since the VAR deletion mutant secADelta519-547 displayed a wild-type rate of cellular growth and protein export.[secA] (Mus musculus) PubMed

 9581.

The transcriptomes of S. coelicolor M145 and an RNase III (rnc)-null mutant of that strain are reported.[RNase III] (Mus musculus) PubMed

 9582.

These results suggest that Bdf2 modulates chromatin structure to coordinate DNA replication and S-phase stress response (Bdf2). (Mus musculus) PubMed

 9583.

Xanthomonas campestris pathovar campestris type III effector AvrAC enhances virulence and inhibits plant immunity by specifically targeting Arabidopsis BIK1 and RIPK, two receptor-like cytoplasmic kinases known to mediate immune signalling.[AvrAC] (Mus musculus) PubMed

 9584.

The myristate moiety and amino terminus of L1 region are needed for virus entry. (Mus musculus) PubMed

 9585.

HCV NS5B is involved in virus morphogenesis. (Mus musculus) PubMed

 9586.

Both the N-terminal periplasmic and the C-terminal periplasmic loops are important for GtrIV function. [GtrIV] (Mus musculus) PubMed

 9587.

The results demonstrated that PspC is sufficient for adhesion and subsequent invasion of host epithelial cells expressing the human polymeric Ig receptor (hpIgR).[PspC] (Mus musculus) PubMed

 9588.

TaLsi1 is indeed a functional Si transporter as its expression in Arabidopsis leads to increased Si uptake.[TaLsi1] (Mus musculus) PubMed

 9589.

Both spe and samdc mutants behaved as spermidine auxotrophs, and were more sensitive than the wild-type strain to different stress conditions.[spe, samdc] (Mus musculus) PubMed

 9590.

data suggest that cellular MurA predominantly exists in a tightly locked complex with UDP-N-acetylmuramic acid.[MurA] (Mus musculus) PubMed

 9591.

OsLEA4 protein enhanced the tolerance of E. coli recombinant to high salinity, heat, freezing, and UV radiation, which suggested that OsLEA4 protein may play a protective role under stressed conditions. (Mus musculus) PubMed

 9592.

The structure of the Pdp1 PWWP domain, which is the first PWWP domain identified which binds to methyl-lysine at the H4K20 site, was determined in the present study by solution NMR (Mus musculus) PubMed

 9593.

Retroviral cyclin enhances cyclin-dependent kinase-8 activity. [cyclin] (Mus musculus) PubMed

 9594.

Ac79 gene encodes an early gene product and is required for efficient budded virus production. [Ac79] (Mus musculus) PubMed

 9595.

Expression of miR156 is gradually increased during leaf development. miR156 level is positively correlated with leaf developmental time. Overexpression promotes leaf initiation and precocious maturation. [miR156] (Mus musculus) PubMed

 9596.

These results indicate that ubiquitination is an important determinant for localization and regulation of the Aat1p permease in Schizosaccharomyces pombe.[Aat1p] (Mus musculus) PubMed

 9597.

The results demonstrate that the majority of the essential residues of Phosphatidylglycerol::prolipoprotein diacylglyceryl transferase (Lgt) are located in the membrane and that the Lgt signature motif faces the periplasm.[Lgt] (Mus musculus) PubMed

 9598.

OsKOL4/CYP701A8 plays a role in the diterpenoid metabolism of rice. [KOL4] (Mus musculus) PubMed

 9599.

Data suggest distinct expression patterns for isoenzymes nuc1 and nuc2 in different growth stages; expression appears to be under control of sae regulatory system in strain RN4220. [nuc; thermostable nuclease] (Mus musculus) PubMed

 9600.

Atg13 has an additional function independent of Ulk1/2 and that Atg13 and FIP200 act in concert during autophagy induction.[FIP200] (Mus musculus) PubMed

 9601.

Taken together, these results suggest that the ITAM-like sequences in Coxsackievirus B3 VP2 can not only affect viral structure but also act as signals in pathogenesis.[VP2] (Mus musculus) PubMed

 9602.

results support Pfnek3 as a novel dual-specificity kinase, even though it displays a HGDLKSTN motif in the catalytic loop that resembles the consensus HRDLKxxN signature found in the serine/threonine kinases (nek3) (Mus musculus) PubMed

 9603.

This is the first report which demonstrates that ornithine decarboxylase from Entamoeba histolytica is functional in the dimeric form.[ornithine decarboxylase] (Mus musculus) PubMed

 9604.

The authors describe a novel Schistosoma mansoni G protein-coupled receptor (named SmGPR-3) that was shown to be activated by dopamine, a well established neurotransmitter of the schistosome nervous system.[SmGPR-3] (Mus musculus) PubMed

 9605.

ESR1 expression may be manifested by a single-CpG-site based methylation difference impairing transcription factor binding (Mus musculus) PubMed

 9606.

These and other results suggest that rcbA helps to maintain the integrity of the bacterial chromosome by lowering the steady-state level of double-strand breaks.[rcbA] (Mus musculus) PubMed

 9607.

These results show that NspC levels inversely regulate biofilm and motility and implicate the presence of an effective feedback mechanism maintaining norspermidine homeostasis in Vibrio cholerae.[NspC] (Mus musculus) PubMed

 9608.

Bluetongue virus induces IFN-alpha/beta in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.[IFN alpha,IFN beta] (Mus musculus) PubMed

 9609.

These data showed that the global regulator phoP was repressed by bovine and murine bile.[phoP] (Mus musculus) PubMed

 9610.

The co-expression of TVP1 and TNHXS1 increased both Na(+)/H(+) antiport and H(+)-PPiase activities and induced the H(+) pumping activity of the endogenous V-ATPase.[TNHXS1] (Mus musculus) PubMed

 9611.

NME1 controls annexin IV and EF-1Balpha amounts by post-translational mechanisms. [EF-1Balpha] (Mus musculus) PubMed

 9612.

CMTM7 functions to link sIgM and BLNK in the plasma membrane.[B-cell receptor] (Mus musculus) PubMed

 9613.

Rcf1 displays overlapping function with another Hig1-related protein, Rcf2 (formerly Aim38), and their joint presence is required for optimal COX enzyme activity and the correct assembly of the cytochrome bc(1)-COX supercomplex [Rcf1 (AIM31)] (Mus musculus) PubMed

 9614.

structure of A. fumigatus UGM to 2.52 A resolution was determined by molecular replacement using the incomplete 2.8 A resolution L. major UGM model.[UDP-galactopyranose mutase] (Mus musculus) PubMed

 9615.

The effects of FKBP12.6 and another structurally similar molecule, FKBP12, which is far more abundant in heart, on the gating of single sheep RyR2 channels, were investigated.[RyR2, FKBP12, FKBP12.6] (Mus musculus) PubMed

 9616.

The role of the NS1 protein in modulating influenza A virulence and host range was assessed by adapting A/Hong Kong/1/1968 (H3N2) (HK-wt) to increased virulence in the mouse.[NS1] (Mus musculus) PubMed

 9617.

Both IscA and ErpA are required for [Fe-S] cluster delivery to the small subunits of the hydrogen-oxidizing hydrogenases.[IscA, ErpA] (Mus musculus) PubMed

 9618.

Msb2 is a glycoprotein that effectively protects C. albicans against killing by antimicrobial peptides histatin-5 and LL-37. [Msb2] (Mus musculus) PubMed

 9619.

xylanase 1 and xylanase 2 showed a pH optimum at pH 6 and similar temperature dependency.[xylanase 1, xylanase 2] (Mus musculus) PubMed

 9620.

The functional characterisation of the orthologue of SSNA1 in the kinetoplastid parasite, Trypanosoma brucei, is reported.[DIP13] (Mus musculus) PubMed

 9621.

A single SNP was identified in the ovine transmembrane protein (TMEM154) that associated with Visna/Maedi virus infection exceeded genome-wide significance (Mus musculus) PubMed

 9622.

SlyD participates in [NiFe] hydrogenase maturation processes. [SlyD] (Mus musculus) PubMed

 9623.

Sphingolipid C9 methyltransferase (SMT1) is required for the virulence of Cryptococcus neoformans. [Sphingolipid C9-methyltransferase] (Mus musculus) PubMed

 9624.

The overexpression of HSG1 increased CO expression by ~400% compared with the control seedling.[HSG1] (Mus musculus) PubMed

 9625.

p27kip1 upregulated by hnRNPC1/2 antagonizes CagA-mediated pathogenesis.[CagA] (Mus musculus) PubMed

 9626.

BarA-UvrY two-component system regulates virulence of uropathogenic E. coli CFT073.[BarA, UvrY] (Mus musculus) PubMed

 9627.

PTC (from Enterococcus faecalis), in addition to using putrescine, can utilize L-ornithine as a poor substrate.[PTC] (Mus musculus) PubMed

 9628.

The targets of Gis1 and the related protein Rph1 in different growth phases, were studied.[Gis1, Rph1] (Mus musculus) PubMed

 9629.

Large fragment (>100 base pairs) pre-S deletion mutation is an important independent predictor for hepatitis B relapse after liver transplantation.[L protein] (Mus musculus) PubMed

 9630.

Horizontal transmission of A/Vietnam/1203/2004 H5N1 (VN/1203) virus in chickens and ducks was not affected by the change of K to E at PB2-627.[PB2] (Mus musculus) PubMed

 9631.

A well-studied allosteric enzyme, E. coli aspartokinase III, is used as a model system, to construct a new algorithm of network, which is based on a new protein dynamics model of energy dissipation.[Aspartokinase] (Mus musculus) PubMed

 9632.

SCO0877 and SCO7173 are pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolor.[SCO0877, SCO7173] (Mus musculus) PubMed

 9633.

DdS4 might influence morphogenesis.[Dds4] (Mus musculus) PubMed

 9634.

PGL1-APG represents a new grain length and weight-controlling pathway in which APG is a negative regulator whose function is inhibited by PGL1.[PGL1, APG] (Mus musculus) PubMed

 9635.

A positively charged region in the tail of UncA (amino acids 1316 to 1402) is necessary for the recognition of modified microtubules.[UncA] (Mus musculus) PubMed

 9636.

Klp5/6 bind tightly to free tubulin heterodimers.[Klp5, Klp6] (Mus musculus) PubMed

 9637.

These findings are consistent with the hypothesis that low PLN/SERCA ratio in atrial tissue enables faster sarcoplasmic reticulum Ca(2+) reuptake.[SERCA, Phospholamban] (Mus musculus) PubMed

 9638.

The ability of Enterobacter cloacae isolates to form biofilms was significantly correlated with the mRNA expression level of the csgA and csgD genes.[csgA, csgD] (Mus musculus) PubMed

 9639.

A full-length cDNA of VvAADC (encoding aromatic amino acid decarboxylase) was firstly cloned from the berries of 'Vidal blanc', an interspecific hybrid variety of Vitis vinifera x Vitis riparia.[VvAADC] (Mus musculus) PubMed

 9640.

These observations suggest that the association of Asf1p and Vip1p may be implicated in transcription elongation.[Vip1p, Asf1p] (Mus musculus) PubMed

 9641.

ehhmbp26 gene was repressed totally by free iron, whereas ehhmbp45 gene showed clearly detectable mRNA levels.[Ehhmbp26 and Ehhmbp45] (Mus musculus) PubMed

 9642.

A genetic interaction between NDPK and AMPK in Dictyostelium in that NDPK is required for the phenotypic effects of activated AMPK is demonstrated. [NDPK & AMPK] (Mus musculus) PubMed

 9643.

These results suggest that RIC-7 promotes dense core vesicles-mediated neuropeptide secretion (Mus musculus) PubMed

 9644.

The authors demonstrate that the regulatory protein NorR regulates the expression of NO detoxification genes hmpA and nnrS, and that all three are critical for resisting low levels of NO stress under microaerobic conditions in vitro.[NorR, hmpA, nnrS] (Mus musculus) PubMed

 9645.

solvent content is nearly 70%, with S15 bridging parallel infinite helices of proteinase across large solvent channels[proteinase] (Mus musculus) PubMed

 9646.

crystals of aminoglycoside acetyltransferase belonged to the hexagonal space group P6(5), with approximate unit-cell parameters a = 107.75, c = 37.33 A, and contained one molecule in the asymmetric unit[aminoglycoside acetyltransferase:AF337947 ] (Mus musculus) PubMed

 9647.

DEPG1 plays roles in the interactions between rice and bacterial leaf streak pathogen Xanthomonas oryzae pv. oryzicola. (Mus musculus) PubMed

 9648.

crystal diffracted X-rays to 3.65 A resolution and belonged to space group C222, with unit-cell parameters a = 155.1, b = 206.7, c = 38.5 A. The crystal contained one OsAREB8-DNA complex in the asymmetric unit[AREB8] (Mus musculus) PubMed

 9649.

structure of A. fumigatus UGM to 2.52 A resolution was determined by molecular replacement using the incomplete 2.8 A resolution L. major UGM model.[UDP-galactopyranose mutase] (Mus musculus) PubMed

 9650.

c-Src phosphorylated EPIYA-C & -D. c-Abl phosphorylated EPIYA-A, -B, -C, -D. CagA molecules were phosphorylated on 1 or 2 EPIYA motifs, but never simultaneously on 3 motifs. CagA. (Mus musculus) PubMed

 9651.

Interactions between M1-family aminopeptidase (PfA-M1) and the backbone atoms of the substrate residues as well as the sidechains further contributed to the catalytic efficiency of substrate hydrolysis. [PfA-M1] (Mus musculus) PubMed

 9652.

the host erythrocyte receptor glycophorin B directly interacts with the DBL domain of parasite EBL-1, and the core binding site is contained within the 69 amino acid F2i region (residues 601-669) of the DBL domain. (Mus musculus) PubMed

 9653.

subtilisin-like protease 3 (PfSUB3) was detected in schizont stage parasites but not in ring and trophozoite stage parasites suggesting some role in late asexual blood stages. [PfSUB3] (Mus musculus) PubMed

 9654.

Point mutations in wchA are responsible for the non-typability of Streptococcus pneumoniae isolates[ wchA ] (Mus musculus) PubMed

 9655.

REVIEW of all known host and bacterial protein substrates for SpeB, their cleavage sites, and discuss the role of this enzyme in streptococcal pathogenesis [SpeB] (Mus musculus) PubMed

 9656.

TgSis1 showed to be a cytosolic Hsp40 which co-immunoprecipitated with T. gondii Hsp70 and Hsp90. [Sis1] (Mus musculus) PubMed

 9657.

genetic analyses revealed the requirement of members of the NODE complex recently identified in embryonic stem (ES) cells, and of the OCT4 partner sox-2, for the initiation of this natural direct reprogramming event [NODE] (Mus musculus) PubMed

 9658.

This study showed that while translation of the dihydrouridine synthase gene dusB is low, unusual mechanisms operate to enable robust translation of fis.[fis] (Mus musculus) PubMed

 9659.

The effects of stop triplets on the growth of an E. coli strain deficient in pfrA protein are reported.[prfA] (Mus musculus) PubMed

 9660.

This study showed that mutation of pitA, partially suppresses the alpha-methyl glucoside growth defect of an sgrS mutant.[sgrS] (Mus musculus) PubMed

 9661.

The results demonstrate that Mfd promotes the rapid recovery of gene expression following UV-induced damage in E. coli.[Mfd] (Mus musculus) PubMed

 9662.

Substrate binding to CLC-ec1 is synergistic rather than antagonistic: chloride binding induces protonation of a crucial glutamate. [CLC-ec1] (Mus musculus) PubMed

 9663.

The authors showed that stp1 is important in vancomycin susceptibility and cell wall biosynthesis and regulates expression of virulence genes, including a hemolysin, superantigen-like protein, and phenol-soluble modulin.[stp1] (Mus musculus) PubMed

 9664.

function of ArgR in Streptomyces coelicolor [ArgR] (Mus musculus) PubMed

 9665.

binding of the ion to the channel protein seemingly explains certain gating, ion selectivity, and permeation properties[KcsA] (Mus musculus) PubMed

 9666.

The study presents a 3.3-A crystal structure of the motor domain of Saccharomyces cerevisiae cytoplasmic dynein, crystallized in the absence of nucleotides. [dynein] (Mus musculus) PubMed

 9667.

C-terminal extension functions as a part of Mip1 polymerase domain that stabilizes the substrate primer end at the polymerase active site, and is therefore required for efficient mitochondrial DNA replication in vivo.[Mip1] (Mus musculus) PubMed

 9668.

A structural model for the ISW1a chromatin remodelling factor from Saccharomyces cerevisiae in complex with a dinucleosome substrate was constructed from the X-ray structures of ISW1a.[ISW1a] (Mus musculus) PubMed

 9669.

Heterochromatin protein 1 forms distinct DNA methylation and histone deacetylation complexes that work in parallel to assemble silent chromatin in N. crassa. [Heterochromatin protein 1] (Mus musculus) PubMed

 9670.

The authors demonstrate that small interfering RNA (siRNA)-mediated depletion of I3 causes a significant decrease in the accumulation of progeny genomes and that this reduction diminishes the yield of infectious virus.[I3] (Mus musculus) PubMed

 9671.

Synchronization between protein A-capsid protein interaction and its subcellular localization is imperative to confer packaging specificity.[capsid protein] (Mus musculus) PubMed

 9672.

the region constituting residues 240-252 of ELon is important for ATPase activity, substrate translocation and protein degradation (Mus musculus) PubMed

 9673.

The role of WcaJ in the synthesis of colanic acid (CA) capsule was studied.[WcaJ] (Mus musculus) PubMed

 9674.

It is suggested that the most prevalent G1P lineage strains in Sapporo obtained some survival advantages by changing the neutralization domains of VP7. (Mus musculus) PubMed

 9675.

BzpR regulates aspects of the development program in Dictyostelium, serving as a downstream effector of eIF2alpha phosphorylation [eIF2alpha kinase][BzpR] (Mus musculus) PubMed

 9676.

[trypomastigote small surface antigen TSSA] TSSA functions as a parasite adhesin, engaging surface receptor(s) and inducing signaling pathways on the host cell as a prerequisite for parasite internalization. (Mus musculus) PubMed

 9677.

the crystal structure of the receiver domain of spr1814 (spr1814(R)) determined in the absence and presence of beryllofluoride as a phosphoryl analog was reported.[spr1814] (Mus musculus) PubMed

 9678.

the function of protein phosphatase type 2A regulatory unit (Mus musculus) PubMed

 9679.

TLR7 agonist imiquimod induces macrophage autophagy in atherosclerotic plaques, but stimulates plaque progression through cytokine release and enhanced infiltration of inflammatory cells. (Mus musculus) PubMed

 9680.

Mechanistically, Kaposi's sarcoma-associated herpesvirus viral OX2 protein and CD200 expression on antigen presenting cells suppressed the phosphorylation of ERK1/2 mitogen-activated protein kinase in responding T cells.[OX2] (Mus musculus) PubMed

 9681.

Collectively, these results suggest that BrpA plays a role in the regulation of cell envelope integrity and that deficiency of BrpA diminishes the virulence of OMZ175, a highly invasive strain of Streptococcus mutans.[BrpA] (Mus musculus) PubMed

 9682.

These results show a significant association between mutant ropB alleles, decreased activity of its major regulatory target SpeB, and pharyngitis.[ropB] (Mus musculus) PubMed

 9683.

In this study, a Corynebacterium glutamicum gamma-aminobutyric acid-specific transporter (GabP(Cg)) encoded by ncgl0464 was identified and characterized.[GabP(Cg)] (Mus musculus) PubMed

 9684.

delipidation of Atg8 by Atg4 on different organelle membranes promotes autophagosome formation.[Atg4, Atg8] (Mus musculus) PubMed

 9685.

co-localized with H V-ATPase [NHA1] localized in the apical plasma membrane of stellate cells in distal Malpighian tubules [NHA2] (Mus musculus) PubMed

 9686.

prestin proteins appear suited for central roles in bicarbonate, sulfate and oxalate metabolism including generating the high pH conditions measured in the Dipteran midgut lumen [prestinA, prestinB] (Mus musculus) PubMed

 9687.

DAHPS is a key regulatory enzyme of the shikimate pathway.[DAHPS] (Mus musculus) PubMed

 9688.

Expression of ZmbZIP60 is strongly induced by a wide spectrum of stresses, including dehydration, high salinity, abscisic acid and tunicamycin treatments.[ZmbZIP60] (Mus musculus) PubMed

 9689.

a novel role of cyclase associated protein (CAP) in regulating cell adhesion mechanisms during development that might be envisioned to unravel the functions of mammalian CAP during animal embryogenesis. (Mus musculus) PubMed

 9690.

Deletion of either pesL (DeltapesL) or pes1 (Deltapes1) resulted in complete loss of fumigaclavine C biosynthesis.[pesL, pes1] (Mus musculus) PubMed

 9691.

These results support the notion that OsUPS plays an important role in the inorganic phosphate signaling pathway through the ubiquitin-26S proteasome system.[OsUPS] (Mus musculus) PubMed

 9692.

study found that P. berghei CDC20 is not required for asexual multiplication but is essential for male gamete formation [CDC20] (Mus musculus) PubMed

 9693.

Regardless of the d-xylose concentration applied and whether CreA was functional, xlnR was constitutively expressed at a low level.[CreA, xlnR] (Mus musculus) PubMed

 9694.

Knockdown of SLC7 proteins results in reduced TOR signaling in the female fat body and reduced egg numbers after a blood meal. [SLC7] (Mus musculus) PubMed

 9695.

Loss of function of PpMRE11 or PpRAD50 strongly and specifically inhibited gene targeting. In contrast, disruption of the PpNBS1 gene retained the wild-type capacity to integrate transforming DNA efficiently at homologous loci (MRE11, RAD50 and NBS1). (Mus musculus) PubMed

 9696.

This work demonstrates that PAF (platelet-activating factor) receptor is expressed in Iberian pig spermatozoa and that its stimulation by PAF regulates the calcium-induced acrosome reaction.[PAF receptor] (Mus musculus) PubMed

 9697.

oxyR mutants were sensitive to hydrogen peroxide, while soxRS mutants were sensitive to superoxide.[oxyR, soxRS] (Mus musculus) PubMed

 9698.

the double deletion of cortexillin (ctx) I and II alters the actin cytoskeleton and substantially inhibits all molecular responses to extracellular cAMP.[cortexillin I][cortexillin II] (Mus musculus) PubMed

 9699.

NSP1 and NSP2 are indispensable for strigolactone (SL) biosynthesis in the legume Medicago truncatula and in rice][NSP1, NSP2] (Mus musculus) PubMed

 9700.

IRE1 mediates the unconventional splicing of bZIP50 mRNA. [IRE1;bZIP50] (Mus musculus) PubMed

 9701.

DNA damage neither down-regulates CDKB2;1 nor induces endoreduplication. Knockdown of CDKB2;1 induces polyploidy in rice.[CDKB2;1] (Mus musculus) PubMed

 9702.

Os-GI functions to maintain bioactive gibberellin level through the regulation of the gibberellin-deactivating enzyme genes in rice. [GIGANTEA] (Mus musculus) PubMed

 9703.

Cdc28 was destabilized in response to depletion of Hsp90 and Cdc28 physically interacts with Hsp90, implicating this major cell cycle regulator as a novel Hsp90 client protein in C. albicans [Cdc28][Hsp90] (Mus musculus) PubMed

 9704.

The metalloprotease toxolysin-1 (TLN1), is a soluble rhoptry protein, secreted during invasion. TLN1 is targeted to rhoptries via an N-terminal pro-domain. Pro-domain cleavage occurs in rhoptries, processing of the C-terminus at an earlier stage. (Mus musculus) PubMed

 9705.

Activation of plasminogen to plasmin by staphylokinase or tissue plasminogen activator decreased in the presence of TPI, whereas Triosephosphate isomerase (TPI) was degraded by plasmin. [TPI] (Mus musculus) PubMed

 9706.

role of conserved residues in protein function [yjdL] (Mus musculus) PubMed

 9707.

mutations in glmM appear to influence bacterial cell growth and morphology, independent of the carbon source [glmM] (Mus musculus) PubMed

 9708.

marrow from SAMP6 mice had diminished capacity for long-term hematopoiesis, increased radiosensitivity, and reduced proliferative capacity [SAMP6] (Mus musculus) PubMed

 9709.

The secretion of most proteins in S. aureus is dependent on the type I signal peptidase(SPase)-mediated cleavage of the N-terminal signal peptide that targets a protein to the general secretory pathway.[SPase] (Mus musculus) PubMed

 9710.

This study showed that the major substrate of the T2SS in EPEC is SslE, an outer membrane lipoprotein, and that a function type II secretion system (T2SS) is essential for biofilm formation.[ss1E; T2SS] (Mus musculus) PubMed

 9711.

The same structure and a second crystal form of FtsA reveal that FtsA forms actin-like protofilaments with a repeat of 48 A. (Mus musculus) PubMed

 9712.

Under environmental surplus, PHO84 overexpression augmented heavy metal accumulation by the wild type.[PHO84] (Mus musculus) PubMed

 9713.

C-terminal region of S. cerevisiae GK is involved in the folding and/or the stability of the kinase domain [GK] (Mus musculus) PubMed

 9714.

CP148 is an essential factor for the formation of the centrosomal corona, which in turn is required for centrosome/centromere linkage. [CP148] (Mus musculus) PubMed

 9715.

results suggest that the function of OsYSL16 in Fe-homeostasis is to enable distribution of iron within a plant.[OsYSL16] (Mus musculus) PubMed

 9716.

By using a rat biofilm model, the authors further confirmed the role of Efg1 in the tolerance of Candida albicans biofilms to miconazole when grown in vivo.[Efg1] (Mus musculus) PubMed

 9717.

Based on the interactions between SnRK2s and its targets and the expression pattern, we suggest that VvSnRK2.1 and VvSnRK2.6, can be considered the major VvSnRK2 candidates involved in the stomata response to abiotic stress. [VvSnRK2.1 and VvSnRK2.6] (Mus musculus) PubMed

 9718.

NS5A inhibits the transcription of hepcidin mRNA and expression of hepcidin protein, inducing hepatic intracellular iron storage. [NS5a] (Mus musculus) PubMed

 9719.

the crystal structure of VctP from V. cholerae N16961 at 1.7A resolution.(VctP) (Mus musculus) PubMed

 9720.

a novel drought responsive histidine kinase gene was identified and designated as . [ZmHK9] (Mus musculus) PubMed

 9721.

U. maydis mutants lacking the peroxisomal isoforms of Gapdh or Pgk1 showed reduced virulence [Pgk1; GAPDH?] (Mus musculus) PubMed

 9722.

cryptic peroxisomal targeting of GpdA (GAPDH) and PgkA (PGK) in the ascomycetous fungus A. nidulans [GpdA; PgkA] (Mus musculus) PubMed

 9723.

RNA-Induced Transcriptional Silencing complex is guided to these meiotic targets by the RNA-binding protein Mmi1 and its associated RNA surveillance machinery that together degrade selective meiotic mRNAs during vegetative growth.[Mmi1] (Mus musculus) PubMed

 9724.

the TssL structure is the prototype for the members of the TssL and IcmH/DotU families (Mus musculus) PubMed

 9725.

C. reinhardtii VTC2, like its plant homologs, is a highly regulated enzyme in ascorbate biosynthesis in green algae [VTC2] (Mus musculus) PubMed

 9726.

In the present study, authors have cloned a gene named CEMMP62 from Caenorhabditis elegans, the putative 62-kDa protein that contained 579 residues with matrix metalloproteinase-conserved catalytic domain.[CEMMP62] (Mus musculus) PubMed

 9727.

Mutation of rice STR1 and STR2 interferes with arbuscule formation. [STR1; STR2] (Mus musculus) PubMed

 9728.

The induction of OsbZIP74 splicing is much suppressed in the OsIRE1 knock-down rice plants, indicating the involvement of OsIRE1 in OsbZIP74 splicing.[IRE1, bZIP74] (Mus musculus) PubMed

 9729.

Srv regulated control of SpeB may mediate biofilm formation and dispersal in diverse strain backgrounds [srv, strain M1 GAS] (Mus musculus) PubMed

 9730.

The AP1-M6 pilus ancillary protein mediates epithelial cell adherence as well as biofilm and microcolony formation. [pilus ancillary protein 1] (Mus musculus) PubMed

 9731.

Crr1, a novel response regulator restricted to the Candida CTG clade, regulates the response of C. albicans cells to hydrogen peroxide in a Hog1-independent manner that requires the function of the conserved phospho-aspartate [Crr1] (Mus musculus) PubMed

 9732.

An intact 3c appears to be essential for intestinal replication. [3C] (Mus musculus) PubMed

 9733.

clxA has a role in stress response, virulence and proteolytic secretome of the fungal pathogen Aspergillus fumigatus [clxA] (Mus musculus) PubMed

 9734.

The C-terminal as well as the central cysteine-rich domain of Plasmodium falciparum RON2 interact with Plasmodium falciparum AMA1.[RON2] (Mus musculus) PubMed

 9735.

These results indicate that Plasmodium yoelii macrophage migration inhibitory factor potentially modulates monocyte recruitment and activation during infection of Plasmodium yoelii erythrocytic stages.[macrophage migration inhibitory factor] (Mus musculus) PubMed

 9736.

Histone-like nucleoid structuring protein (H-NS) is a repressor of exopolysaccharide biosynthesis genes and biofilm formation [H-NS] (Mus musculus) PubMed

 9737.

IEP modulates autoregulation of its gene through the consensus near the transcription initiation site and the TATA box.[IE] (Mus musculus) PubMed

 9738.

srtE1/E2 double mutants are delayed in aerial hyphae formation, do not sporulate and fail to display all short chaplins on their aerial surfaces. [SrtE1; SrtE2] (Mus musculus) PubMed

 9739.

Sequence analyses of UpaG and EhaG homologues from several E. coli genomes revealed grouping of the proteins in clades almost exclusively represented by distinct E. coli pathotypes. [EhaG] (Mus musculus) PubMed

 9740.

both adenylate cyclase and protein kinase A are involved in light-modulated cellulase gene expression in T. reesei and have a dampening effect on the light responsiveness of this process. [cellulase, PKA, ACY1] (Mus musculus) PubMed

 9741.

RsmA is a bZIP protein involved in secondary metabolism regulation and fungivore resistance. [RsmA] (Mus musculus) PubMed

 9742.

These data suggest that RPL1 regulated phenotypic plasticity likely through its involvement in epigenetic processes affecting responses of the plant to phytohormones.[RPL1] (Mus musculus) PubMed

 9743.

using bioinformatics and functional expression, characterized two additional honeybee genes encoding membrane-bound adenylyl cyclases (ACs); the proteins were designated AmAC2t and AmAC8[AC2t,AC8] (Mus musculus) PubMed

 9744.

SCO3644 codes for a kynurenine formamidase, SCO3645 for a kynureninase and SCO3646 for a tryptophan 2,3-dioxygenase.[SCO3644, SCO3645, SCO3646] (Mus musculus) PubMed

 9745.

In this study, the authors demonstrated that Pdc2p interacts with the upstream region of THI genes and PDC5.[Pdc2] (Mus musculus) PubMed

 9746.

Thus, a relationship between the low-molecular-weight PBP5, PBP6 and cytoplasmic FtsZ ultimately affects cell division and overall shape.[ PBP5, PBP6, FtsZ] (Mus musculus) PubMed

 9747.

EPA1 (epithelial adhesin 1) is induced in lag phase. [EPA1] (Mus musculus) PubMed

 9748.

Phosphomannose isomerase was found to be essential for parasite growth.[phosphomannose isomerase] (Mus musculus) PubMed

 9749.

In contrast to DeltaaoxA, DeltacycA was found to be significantly impaired in conidia germination, growth in normoxia and hypoxia, and displayed attenuated virulence.[aoxA, cycA] (Mus musculus) PubMed

 9750.

Thus, opuABCD reduces bacterial colonization via a mechanism that limits trehalose production.[opuABCD] (Mus musculus) PubMed

 9751.

Both CagA-SHP2 and CagA-PAR1 interactions are involved in the pathogenicity of cagA-positive Helicobacter pylori.[CagA] (Mus musculus) PubMed

 9752.

operon containing the hvtA gene is homologous to the operon in V. cholerae containing the hemin receptor gene hutR suggesting a vertical transmission of the hvtA cluster from V. cholerae to V. vulnificus[HvtA] (Mus musculus) PubMed

 9753.

UmRrm75 is involved in dimorphism and virulence. [UmRrm75] (Mus musculus) PubMed

 9754.

The sORF (called iroK) encodes a 21 amino cid peptide, which when translated confers a 133% (ca. 20 g/L) increase in resistance to 3-hydroxypropionic acid. (Mus musculus) PubMed

 9755.

ypa1 and ypa2 genes are essential for survival only at low temperatures. [ypa1;ypa2] (Mus musculus) PubMed

 9756.

vBOR1 encodes an efflux B transporter located in the plasma membrane and is differentially expressed in reproductive tissues. VvBOR1 is preferentially expressed in flowers at anthesis. [VvBOR1] (Mus musculus) PubMed

 9757.

generated a monoclonal antibody, designated 1.F6F6, against the C-type lectin-like domain-5 of the porcine CD205 and showed that it recognizes a protein band of approximately 200 kDa by Western Blot analysis in mesenteric lymph nodes cells[CD205] (Mus musculus) PubMed

 9758.

Wsp1 is downstream of Cin1 and regulates vesicle transport and actin cytoskeleton as an effector of Cdc42 and Rac1 (Mus musculus) PubMed

 9759.

Inducible RNAi-mediated knock-down of an adenylyl cyclase subfamily that includes ESAG4 and two ESAG4-like GRESAG4 (ESAG4L) genes, decreased total adenylyl cyclase activity and induced a lethal phenotype linked to impaired cytokinesis.[ESAG4] (Mus musculus) PubMed

 9760.

These data strongly support the hypothesis that the secreted kinase ROP18 is involved in several complex cellular pathways for the invasion and commandeering of host functions.[ROP18] (Mus musculus) PubMed

 9761.

miR-301a regulates the function of myelin-reactive T-helper type 17 cells, and with PIAS3 is a candidate for therapeutic targeting for the control of autoimmune demyelination. (Mus musculus) PubMed

 9762.

NBS-Str1 and BLEC-Str8 upstream regulatory sequences are inducible by heavy metal, copper and manganese. (Mus musculus) PubMed

 9763.

show that Isw1a displays a highly cooperative ATP-independent binding to and bridging between DNA segments[Isw1a] (Mus musculus) PubMed

 9764.

Evolutionary rates in the hypervariable region 1 (HVR1) region of the E2 gene were significantly higher in self-resolvers than those in persistence subjects during early infection[HVR1 ] (Mus musculus) PubMed

 9765.

baseline polymorphism (E62D) of nonstructural protein 5A did not contribute resistance to BMS-790052; however, the linked variant, Q30R-E62D[nonstructural protein 5A ] (Mus musculus) PubMed

 9766.

Pga13 is a wall-localized protein that contributes to cell wall synthesis and is important for acquiring normal surface properties. [Pga13] (Mus musculus) PubMed

 9767.

eight ZmPMP3 genes were cloned from maize and responsive to salt, drought, cold and abscisic acid. The eight ZmPMP3s were membrane proteins and their sequences in trans-membrane regions were highly conserved. [PMP3] (Mus musculus) PubMed

 9768.

SnRK1 activities appeared to modulate developmental processes in the plants.[SnRK1] (Mus musculus) PubMed

 9769.

Ena1 and Nha1 play redundant and discrete roles in cation homeostasis, pH regulation, membrane potential, and virulence in C. neoformans. [Ena1 and Nha1] (Mus musculus) PubMed

 9770.

NhaP1 protein is a functional K(+)(Na(+))/H(+) antiporter of the CPA1 family that is required for bacterial pH homeostasis and growth in an acidic environment. [NhaP1 (Mus musculus) PubMed

 9771.

The authors conclude that whilst the basic function of HslV may be conserved in Leishmania, its organisation and interaction with its canonical complex partner HslU is not.[HslV, HslU] (Mus musculus) PubMed

 9772.

The metE promoter is responsible for the reconstitution of MetE overexpression in GroE-depleted cells. [GroE] (Mus musculus) PubMed

 9773.

loss of SPM1 decreases overall parasite fitness and eliminates the stability of subpellicular microtubules to detergent extraction.(SPM1) (Mus musculus) PubMed

 9774.

cloning of P-selectin glycoprotein ligand-1 (PSGL-1); results indicate that the general domain structure of PSGL-1 protein is conserved among species, and zebrafish PSGL-1 plays important roles in embryonic development [PSGL-1] (Mus musculus) PubMed

 9775.

The authors concluded that ingestion of E. coli was regulated by transmembrane kinase 39 and partially shared the acetylated low density lipoprotein cholesterol uptake pathway.[transmembrane kinase 39] (Mus musculus) PubMed

 9776.

Here, the authors report the surprising extra-glycosomal localisation of a PTS-2 bearing trypanosomal hexokinase, TbHK2.[HK2] (Mus musculus) PubMed

 9777.

These data indicate that the endogenous nicotinamidase is essential for Leishmania development in the sand fly after the blood meal has been digested and the remnants defecated.[nicotinamidase encoded by Lipnc1] (Mus musculus) PubMed

 9778.

The apical growth determinant DivIVA anchors the chromosomal origins at the cell poles through direct physical interaction with ParB. [DivIVA] (Mus musculus) PubMed

 9779.

Experiments conducted with fliC-expressing variants indicated that unilateral flagellar phase variation was caused by the deletion of an approximately 35 kb DNA region containing the flnA gene from diverse excision sites (flnA). (Mus musculus) PubMed

 9780.

The vapBC operon of S. enterica is under complex transcriptional regulation by VapB and VapC (VapB and VapC). (Mus musculus) PubMed

 9781.

Expression of OsbZIP46 was strongly induced by drought, heat, hydrogen peroxide, and abscisic acid (ABA) treatment; however, it was not induced by salt and cold stresses.[OsbZIP46] (Mus musculus) PubMed

 9782.

findings show that TE coexpresses with MOC1 in the axil of leaves, where the APC/C(TE) complex mediates the degradation of MOC1 by the ubiquitin-26S proteasome pathway [TE,MOC1] (Mus musculus) PubMed

 9783.

These findings provide new insight into nutrients, Rhb1-TOR signaling, and expression of C. albicans virulence factor.(SAP2) (Mus musculus) PubMed

 9784.

Over-expression of inactive GlNek1 delays disassembly of the parental attachment disc and cytokinesis, whilst over-expression of either wild type GlNek1 or inactive mutant GlNek2 inhibits excystation.[Nek1, Nek2] (Mus musculus) PubMed

 9785.

Mbx2 mediates invasive growth and flocculation via the transcriptional activation of gsf2(+) in fission yeast (Mus musculus) PubMed

 9786.

that SpHMT1 function requires phytochelatins in Arabidopsis, and it is feasible to promote food safety by engineering plants using SpHMT1 to decrease metal accumulation in edible tissues.[SpHMT1] (Mus musculus) PubMed

 9787.

TbAIR9 is able to associate with the parasite subpellicular cytoskeleton and plays a role in cytokinesis in bloodstream trypanosomes. It also plays an important role in the spatial positioning of the nucleus. [TbAIR9] (Mus musculus) PubMed

 9788.

NdnR binds to the promoter region of the ndnR-nadA-nadC-nadS operon involved in NAD de novo biosynthesis, and NAD significantly enhances the DNA binding activity of the NdnR protein. (Mus musculus) PubMed

 9789.

The results indicate that GSTD1 and GSTD2 have unique biochemical characteristics, but they do not play major roles in permethrin resistance. [GSTD1, GSTD2] (Mus musculus) PubMed

 9790.

Finally, in order to better understand the physiological role of both sirtuins, we investigated the expression of these genes in young leaves, mature leaves, and berries sampled at different growing stages. [VvSRT1 and VvSRT2] (Mus musculus) PubMed

 9791.

We have identified EDI3, a key enzyme controlling GPC and choline metabolism; Because inhibition of it corrects the GPC/PC ratio and decreases the migration capacity of tumor cells, it represents a possible target for therapeutic intervention.[edi3] (Mus musculus) PubMed

 9792.

isolated DR2539, a novel regulator of intracellular Mn/Fe homeostas; findings show that DR2539, a novel regulator of intracellular Mn/Fe homeostasis binds specifically to the MntH promoter [DR2539] (Mus musculus) PubMed

 9793.

OsIBR5 is a mitogen-activated protein kinase (MAPK) phosphatase (MKP) which was induced by abiotic stresses and decreased tolerance to drought stress in transgenic tobacco plants. [OsIBR5] (Mus musculus) PubMed

 9794.

(Rch1p; RCH1) Rch1p, a novel regulator of cytosolic divalent calcium (Ca2+)homeostasis, expands the functional spectrum of the vertebrate SLC10 family. (Mus musculus) PubMed

 9795.

ClsA (Cardiolipin synthase) depletion produces new phospholipid species in S. coelicolor. Overexpression of clsA results in altered morphology of substrate, aerial hyphae and spores. [ClsA] (Mus musculus) PubMed

 9796.

The results show that MHO1 is a novel synthetic lethal interactor with PLC1, and that both gene products are required for proliferation (MHO1). (Mus musculus) PubMed

 9797.

Diacylglycerol acyltransferase 2(DGAT2) is key enzyme regulating sex pheromone synthesis and release [diacylglycerol acyltransferase 2] (Mus musculus) PubMed

 9798.

CcpA is involved in the regulation of biofilm formation and competence development in Streptococcus gordoni [CcpA and Streptococcus gordonii strain unspecified] (Mus musculus) PubMed

 9799.

Sorted cells expressing high or low levels of Epa1 exhibited high and low adherence to epithelial cells, indicating a link between gene expression noise and potential virulence.(Epa1) (Mus musculus) PubMed

 9800.

Efg1 also has a prominent effect on cell wall structure and composition, strongly affecting the structural glucan part. [Efg1] (Mus musculus) PubMed

 9801.

Thus, A. nidulans PLKA shows some conservation in cell cycle function but may also play novel roles during hyphal morphogenesis and development. (PLKA) (Mus musculus) PubMed

 9802.

The interaction was significantly altered in 35 out of 69 clones when residue V266 was mutated, indicating that this residue has an important function during substrate binding.[HtrA] (Mus musculus) PubMed

 9803.

PratA influences Mn homeostasis by binding Mn and transporting it to the photosystem II D1 protein. [PratA] (Mus musculus) PubMed

 9804.

The ppr2263 mutation causes growth defects in kernels and seedlings. PPR2263 is required for RNA editing in the mitochondrial NADH dehydrogenase5 and cytochrome b transcripts. [PPR2263] (Mus musculus) PubMed

 9805.

Nuclear localization of deregulated calcium/calmodulin-dependent protein kinasestrongly induced both arbuscular mycorrhizal- and root nodule symbiosis -dependent genes. [CCaMK] (Mus musculus) PubMed

 9806.

SIP2 is a MAPKK that interacts with SymRK and may participate in the regulation of early symbiotic signal transduction and nodule organogenesis. [SIP2] (Mus musculus) PubMed

 9807.

Export of IBIS1 discreted structures in P. berghei-infected red blood cells. [IBIS1] (Mus musculus) PubMed

 9808.

Deletion of floA reduced the growth rate, and deletion of stoA resulted in irregular hyphal morphology. [floA, stoA] (Mus musculus) PubMed

 9809.

[botulinum toxin type A] This review summarizes the literature to update the hypothesis for the mechanism by which botulinum toxin (BoNT) type A can modulate chronic pain. (Mus musculus) PubMed

 9810.

UNC-4 prevents VA motor neurons from responding to a local EGL-20 cue by disabling a canonical Wnt signaling cascade.[Unc-4] (Mus musculus) PubMed

 9811.

structure of membrane-integral pyrophosphatase (TmPPase) in the resting state (TmPPase:Ca:Mg) at 2.6 A resolution and with product bound (TmPPase:Pi2:Mg4) at 4.0 A resolution [TmPPase] (Mus musculus) PubMed

 9812.

The results showed that Pc2 was cleaved to produce two proteins named Pc2-N and Pc2-C.[Pc2] (Mus musculus) PubMed

 9813.

(S)-3-hydroxytridecan-4-one binding to CqsS causes a conformational change that renders His194 in CqsS inaccessible to the catalytic domain. [CqsS] (Mus musculus) PubMed

 9814.

Depletion of the M1-binding protein RACK1 also impairs virus release and RACK1 binding requires the proline residue at position 16 of M1.[M1] (Mus musculus) PubMed

 9815.

These results indicate that wheat ALAD1 has catalytic activity in metabolizing 5-aminolevulinic acid in plastids.[ALAD1] (Mus musculus) PubMed

 9816.

Thus HASPB may be a dual function protein that is shed by the infective metacyclic but retained internally once Leishmania are taken up by macrophages.[HASPB] (Mus musculus) PubMed

 9817.

The role of TBAPE1 in the removal of AP sites is supported by the inverse correlation between the level of AP endonuclease in the cell and the number of endogenously generated abasic sites in its genomic DNA.[TBAPE1] (Mus musculus) PubMed

 9818.

The construction of deletion mutants of three novel HrpL-regulated genes resulted in the identification of additional virulence factors as well as mutants displaying abnormal motility and biofilm phenotypes.[HrpL] (Mus musculus) PubMed

 9819.

PhoP/PhoQ system is involved in the prevention of the delivery to degradative/acidic compartments.[PhoP, PhoQ] (Mus musculus) PubMed

 9820.

Concordant with a functional role of the LovK-LovR two-component system as a negative regulator of the general stress pathway, lovK-lovR-null mutants exhibit increased cell survival after osmotic stress.[LovK, LovR] (Mus musculus) PubMed

 9821.

The pendant-drop method (with drop-shape analysis) and Langmuir trough are applied to investigate the characteristic relaxation times and elasticity of interfacial layers from the protein HFBII hydrophobin. [HFBII] (Mus musculus) PubMed

 9822.

The hypervesiculation phenotype can be reversed to wild-type levels upon the loss of the Rcs phosphorelay response regulator RcsB, suggesting a role for the Rcs phosphorelay in the production of outer membrane vesicles.[RcsB] (Mus musculus) PubMed

 9823.

crystallized and solved the structure of colicin M immunity protein (Cmi) at a resolution of 1.95A [Cmi] (Mus musculus) PubMed

 9824.

In the absence of TonB1, TtpC2 is essential for a fully virulent phenotype as demonstrated using 50% lethal dose (LD(50)) experiments in mice.[TtpC2] (Mus musculus) PubMed

 9825.

Recognition of Epa1p represents a novel mechanism by which human innate immune cells bind fungi, results in phagocytosis and subsequent cytokine production.[Epa1] (Mus musculus) PubMed

 9826.

SSR42 is a novel virulence factor regulatory RNA that contributes to the pathogenesis. [SSR42] (Mus musculus) PubMed

 9827.

The conservation of TbZC3H12 in all kinetoplastids, and TbZC3H13 in Salivaria, suggests that the two proteins may be required for optimal growth at some stage of the parasite life-cycle.[ZC3H12, ZC3H13] (Mus musculus) PubMed

 9828.

the full-length cDNA of a novel insulin-related peptide-binding protein (named BmIBP2) was identified from silkworm, Bombyx mori (Mus musculus) PubMed

 9829.

A transposon inserted into the enhancer region of the zic1 and zic4 genes in the Double anal fin mutant is associated with mesoderm-specific loss of their transcription. Zic1/zic4 induce asymmetric caudal fin development in wild-type embryos.[New Entry] (Mus musculus) PubMed

 9830.

The TLA1 and D2 proteins have a common nine amino acid V-F-L(V)LP-GNAL epitope in their C-terminus (GNAL domain), which is antigenic enough to generate a strong immunity response against either protein. [TLA1] (Mus musculus) PubMed

 9831.

EscA is a crucial component of the type III secretion system. [EscA] (Mus musculus) PubMed

 9832.

These studies provide the first visualization of the conserved complex formed by Ku and DNA ligase IV.[Ku, DNA ligase IV] (Mus musculus) PubMed

 9833.

Coat protein-peptide fusions promoting cell-to-cell transfer only were not competent for virion assembly, whereas long-distance movement was possible only for coat proteins compatible with virus particle formation.[Coat protein] (Mus musculus) PubMed

 9834.

Our loss-of-function and gain-of-function analyses suggest that OsHAP3E plays important pleiotropic roles in vegetative and reproductive development or basic cellular processes in rice. (Mus musculus) PubMed

 9835.

The number of Helicobacter pylori CagA EPIYA C tyrosine phosphorylation motifs influences the pattern of gastritis and the development of gastric carcinoma. (Mus musculus) PubMed

 9836.

In H. pylori, a non-discriminating aspartyl-tRNA synthetase (ND-AspRS)and GatCAB co-evolved to generate an appropriate kinetic system able to reduce translational error level and to ensure a faithful codon reassignment for Asn(ND-AspRS and GatCAB). (Mus musculus) PubMed

 9837.

The results represent the first crystallographic structure analysis of TrmN containing both a THUMP and RFM domain, and hence provide further insight in the contribution of the THUMP domain in tRNA recognition and catalysis (TrmN). (Mus musculus) PubMed

 9838.

The UMPK gene sequence showed complete homology with pyrH gene sequence of all S. aureus strains. [UMPK] (Mus musculus) PubMed

 9839.

These results indicate that the NorA efflux mechanism for gatifloxacin response occurs in at least one strain of Staphylococcus epidermidis, contributing to gatifloxacin resistance.[NorA] (Mus musculus) PubMed

 9840.

Data suggest that the pentatricopeptide repeat (PPR) protein PpPPR_43 is an intron 3-specific splicing factor: [PPR_43] (Mus musculus) PubMed

 9841.

Cdc12p was localized during cell division in P. brasiliensis cells. (Mus musculus) PubMed

 9842.

show that pregnancy-specific glycoprotein (PSG1a), the major variant of PSG released into the circulation during pregnancy[Pregnancy-specific glycoprotein 1a] (Mus musculus) PubMed

 9843.

identification of a reassortant H5 HA/H1N1 virus-comprising H5 HA (from an H5N1 virus) with four mutations and the remaining seven gene segments from a 2009 pandemic H1N1 virus-that was capable of droplet transmission in a ferret model[HA] (Mus musculus) PubMed

 9844.

Our data suggest a role for CyRPA in erythrocyte invasion by the merozoite (Mus musculus) PubMed

 9845.

3.2 A crystal structure of Kluyveromyces polysporus Argonaute (KpAGO) fortuitously complexed with guide RNA originating from small-RNA duplexes autonomously loaded by recombinant KpAGO [AGO] (Mus musculus) PubMed

 9846.

It was shown that male-to-female sex reversal in hotei medaka mutants is not a direct consequence of signaling through anti-Mullerian hormone receptor II in supporting cells, but is mediated by germ cells. [anti-Mullerian hormone receptor II, medaka] (Mus musculus) PubMed

 9847.

structural evidence that AU-rich element (ARE) binding proteins and microRNAs target IL-35 subunit transcripts, by which IL-35 may achieve non-constitutive expression status (IL-35) (Mus musculus) PubMed

 9848.

It was also found that STX-1-induced p53 expression, and activated ATM in mammalian cells.[STX-1] (Mus musculus) PubMed

 9849.

assessment of BGlu1 E386G glycosynthase catalytic abilities [BGlu1] (Mus musculus) PubMed

 9850.

The requirement for KREX2 for RNA editing was assessed in both procyclic and bloodstream forms. The viability of these cells demonstrates that KREX2 is not essential in either life cycle stage, despite certain defects in RNA editing in vivo. (KREX2) (Mus musculus) PubMed

 9851.

Using a novel combination of RNAi screens in C elegans together with detailed follow-up experiments in mouse and human cells, it was shown that NRBP1 is a tumour suppressor that plays a critical role in intestinal cell homoeostasis. [NRBP1, C elegans] (Mus musculus) PubMed

 9852.

The authors show that three amino acids (R204, W207, and R208) located in a loop at the top of the head domain of NP are required for functional interaction with the viral polymerase.[NP] (Mus musculus) PubMed

 9853.

Ectromelia virus DeltaA36R was severely attenuated when used to infect the normally susceptible BALB/c mouse strain.[A36] (Mus musculus) PubMed

 9854.

Description of the first three-dimensional model of B. suis nucleoside hydrolase (nucleoside hydrolase). (Mus musculus) PubMed

 9855.

Data suggest that DEFECTIVE TAPETUM AND MEIOCYTES 1 (DTM1) plays important roles in the endoplasmic reticulum (ER) membrane during early tapetum development: [DTM1] (Mus musculus) PubMed

 9856.

CCPP-1 acts as a tubulin deglutamylase that regulates the localization and velocity of kinesin motors and the structural integrity of microtubules in sensory cilia of a multicellular, living animal. [CCPP-1] (Mus musculus) PubMed

 9857.

ATOM mediates the import of nuclear-encoded proteins into mitochondria and is essential for viability of trypanosomes.[ATOM] (Mus musculus) PubMed

 9858.

The Cnh1 antiporter is involved in the regulation of potassium content and the Ena1 ATPase in sodium detoxification of Candida glabrata cells. (Mus musculus) PubMed

 9859.

Report role of multisite phosphorylation in regulating CLB-3b activity. (Mus musculus) PubMed

 9860.

Here the authors show that M protein and SfbI are anchored simultaneously throughout the cell cycle.[M, SfbI] (Mus musculus) PubMed

 9861.

Sec63's localisation and the resulting binding to BiP near the membrane surface of the ER enable a heterogeneous distribution of BiP within the ER [Sec63][BiP] (Mus musculus) PubMed

 9862.

It appears that Wzx translocases are specific for their O antigen for normal levels of translocation.[Wzx] (Mus musculus) PubMed

 9863.

As a whole, the results show that PodJ's scaffolding role for structural and signalling proteins both contribute to flagellar pole organelle development.[PodJ] (Mus musculus) PubMed

 9864.

the SasA autophosphorylation-enhancing activity of KaiC requires the C-terminal ATPase catalytic site and depends on its phosphorylation state. (Mus musculus) PubMed

 9865.

SNP1343 in 5'untranslated region and SNP2172 in the second intron, consistently had effects on alpha-carotene content and composition with explained phenotypic variations ranging from 8.7% to 34.8% [crtRB3] (Mus musculus) PubMed

 9866.

CslF6 is predominantly expressed in young, expanding tissues and mediates the biosynthesis of mixed-linkage glucans. [CslF6] (Mus musculus) PubMed

 9867.

YSA (young seedling albino) is required for chloroplast development in early seedling leaves. [YSA] (Mus musculus) PubMed

 9868.

Antisense silencing experiments suggested that E1 is an essential gene for parasite viability.[ubiquitin-activating enzyme E1] (Mus musculus) PubMed

 9869.

This study confirms that a putative galactosyltransferase encoded by cj1136 is involved in lipooligosaccharide biosynthesis and is important for Campylobacter jejuni virulence[cj1136]. (Mus musculus) PubMed

 9870.

Mgr2 is a coupling factor of the presequence translocase TIM23 crucial for cell growth at elevated temperature and for efficient protein import [TIM23] (Mus musculus) PubMed

 9871.

optimized SMU2142 crystals diffracted to 2.7 A resolution and belonged to space group P1, with unit-cell parameters a = 53.7, b = 54.1, c = 86.5 A, alpha = 74.2, beta = 73.5, gamma = 83.7 degrees [SMU1234] (Mus musculus) PubMed

 9872.

The catalytic efficiency of germicidin synthase for acyl-acyl carrier protein was 10-fold higher than for acyl-CoA, suggesting a strong preference toward carrier protein starter unit transfer. [germicidin synthase; acyl carrier protein] (Mus musculus) PubMed

 9873.

In this study, the authors confirmed the positive contribution of vad-5 to conidiation by gene complementation.[VAD-5] (Mus musculus) PubMed

 9874.

Global transcription analysis of the CaNRM1 deletion mutant reveals a preferential induction of G1- and G1/S-specific genes.[NRM1] (Mus musculus) PubMed

 9875.

These data indicate that asf1 of Sordaria macrospora encodes a conserved histone chaperone that is required for fruiting body development.[ASF1] (Mus musculus) PubMed

 9876.

The repellent response to cystine was mediated by McpB/C.[McpB, McpC] (Mus musculus) PubMed

 9877.

Thus, one of the functions of BglR is to up-regulate specific beta-glucosidase genes (with the exception of bgl1, which is seemingly under the direct control of Xyr1).[BglR] (Mus musculus) PubMed

 9878.

OsMYB2P-1 is associated with the regulation of root system architecture. [OsMYB2P-1] (Mus musculus) PubMed

 9879.

Shutoff of MYO5 expression correlates with a dramatic reduction in WOR1 expression. [WOR1] (Mus musculus) PubMed

 9880.

ROP9 expression is required for efficient rhizobial symbiosis. Suppression of MtROP9 expression stimulates mycorrhizal colonization. [ROP9] (Mus musculus) PubMed

 9881.

SUNN (Super Numeric Nodules) is required for the modulation of shoot-to-root auxin transport in response to altered nitrogen tissue concentrations in the absence of rhizobia. [SUNN] (Mus musculus) PubMed

 9882.

These results indicate that both PLA1 and PLA2 act downstream of the GA signal transduction pathway to regulate leaf development in rice. PLA1 (Mus musculus) PubMed

 9883.

study presents the crystal structure of Trypanosoma brucei CYP51 in complex with the substrate analog 14alpha-methylenecyclopropyl-Delta7-24,25-dihydrolanosterol [CYP51] (Mus musculus) PubMed

 9884.

The role of myosin-V (MYOV) in hyphal growth, was examined.[MYO V] (Mus musculus) PubMed

 9885.

The MoPEX7-mediated peroxisomal matrix protein import system is required for fungal development and pathogenicity M. oryzae.[PEX7] (Mus musculus) PubMed

 9886.

[CHIP] Yl.Chn1p interacts with mammalian and Saccharomyces cerevisiae members of the Hsp70 family in vitro, and these interactions are differently regulated by Hsp70 co-chaperones (Mus musculus) PubMed

 9887.

yeast Mediator can regulate Pol II elongation at both heat-shock and non-heat-shock genes [RNA polymerase II] (Mus musculus) PubMed

 9888.

[OsHsfA2c, OsHsfB4b, OsClpB] OsHsfA2c specifically interacts with OsClpB-cyt promoter and interaction of OsHsfB4b was seen for all three OsClpB/Hsp100 protein isoforms (Mus musculus) PubMed

 9889.

These findings indicate that baicalin hinders the cell lysis activity of alpha-hemolysin (Hla) through a novel mechanism of interrupting the formation of heptamer.[Hla] (Mus musculus) PubMed

 9890.

the significance of individual point mutations among common ones observed in LMP1 and their combination on activation of the inducible form of nitric oxide synthase [LMP1] (Mus musculus) PubMed

 9891.

IKAP plays pleiotropic roles in both the peripheral and central nervous systems [IKAP/Elp1] (Mus musculus) PubMed

 9892.

TAL effector PthA4 interacts with nuclear factors involved in RNA-dependent processes including a HMG protein that selectively binds poly(U) RNA [PthA4] (Mus musculus) PubMed

 9893.

Collectively, these data demonstrate a negative regulatory role of the spiA gene in whcA-mediated oxidative stress response and provide additional clues on the mechanism by which the whcA gene is regulated.[spiA, whcA] (Mus musculus) PubMed

 9894.

component of signalling pathway is optimally expressed to maximise the accumulation of phosphorylated Fus3 at a fixed time point [Fus3] (Mus musculus) PubMed

 9895.

function of Irc20 and Srs2 in DNA repair and synthesis-dependent strand annealing [Irc20][Srs2] (Mus musculus) PubMed

 9896.

A structural model of the PhoB dimer in the transcription initiation complex has been developed.[PhoB] (Mus musculus) PubMed

 9897.

The authors report that cinA is regulated by ComX in the presence of the competence stimulating peptide (CSP), wherein loss of CinA (strain SmuCinA) results in reduced transformability with or without added CSP by 74- and 15-fold, respectively.[ComX] (Mus musculus) PubMed

 9898.

The present study established the way in which plastidial alpha-glucan phosphorylase (Pho1) synthesizes maltodextrin (MD) which can be the primer for starch biosynthesis in rice endosperm.[Pho1] (Mus musculus) PubMed

 9899.

Abh1 possesses an unexpected DNA incision activity at apurinic/apyrimidinic (AP) sites. (Mus musculus) PubMed

 9900.

Structural and functional analysis of validoxylamine A 7'-phosphate synthase ValL involved in validamycin A biosynthesis [ValL] (Mus musculus) PubMed

 9901.

Macrophage migration, cell polarization and antigen presentation to T-cells require n-cofilin mediated F-actin remodelling.[F-actin] (Mus musculus) PubMed

 9902.

bud2(R682A), was dominant for loss of checkpoint but recessive for bud-site-selection failure, further indicating a separation of function.[Bud2] (Mus musculus) PubMed

 9903.

Gcn5p function and gene regulation in yeast [Gcn5p] (Mus musculus) PubMed

 9904.

HIV p17 highjacks a Rack-1/Jak-1/STAT-1 pathway in macrophages.[p17] (Mus musculus) PubMed

 9905.

according to the ATP availability, NS3 could function regulating the folding or unfolding of viral RNA structures [NS3] (Mus musculus) PubMed

 9906.

The crystal structure of the Escherichia coli ChrR enzyme was solved solved at 2.2 A resolution.[ChrR] (Mus musculus) PubMed

 9907.

ACP mutants unable to interact with SpoT in vivo, were screened.[ACP, SpoT] (Mus musculus) PubMed

 9908.

OsCOI1 is an indispensable signaling component, controlling jasmonic acid-regulated defense against chewing insect in rice plants [COI1] (Mus musculus) PubMed

 9909.

The amino terminal cysteine-rich region of Plasmodium vivax Duffy binding protein (PvDBPII)PvDBPII of Myanmar isolates displays a high level of genetic polymorphism and is under selective pressure.[PvDBPII] (Mus musculus) PubMed

 9910.

is required for pathogenicity of M. oryzae. (Mus musculus) PubMed

 9911.

OsPFA-DSP1 is a functional protein tyrosine phosphatase and may act as a negative regulator in drought stress responses.[OsPFA-DSP1] (Mus musculus) PubMed

 9912.

The mutation of osotp51 indirectly leads to a widespread change in the structure and functions of photosystem I, results in severe photoinhibition, and finally dies, even when grown under very low light intensity.[OSOTP51] (Mus musculus) PubMed

 9913.

The crystal structure of HP-NAP in a Zn(2+)- or Cd(2+)-bound form reveals the binding of two zinc or two cadmium ions and their bridged water molecule at the ferroxidase center. [HP-NAP] (Mus musculus) PubMed

 9914.

role of his67 in Fms1 [Fms1] (Mus musculus) PubMed

 9915.

w information about UGM biochemistry [UGM] (Mus musculus) PubMed

 9916.

essential residues in NADPH-flavin oxidoreductase FRP [FRP] (Mus musculus) PubMed

 9917.

miR-129-3p is critical for cilia formation and function in zebrafish. (Mus musculus) PubMed

 9918.

The distribution of vitamin D 1alpha- and 24-hydroxylase mRNA amounts was similar to mammals, and an immune stimulation altered the amounts of 1alpha- and 24-hydroxylase mRNA in chickens.[vitamin D 1alpha-hydroxylase] (Mus musculus) PubMed

 9919.

Propose that Lnp1p and Sey1p act antagonistically to balance endoplasmic reticular polygonal network formation. (Mus musculus) PubMed

 9920.

Thus, the VPg132 amino acid is essential for both efficient replication and systemic infection.[VPg] (Mus musculus) PubMed

 9921.

Our data therefore reveal that CYP15C1 is the gene responsible for the mod mutation and is essential for juvenile hormones biosynthesis (Mus musculus) PubMed

 9922.

Expression of Escherichia coli CfaC made Salmonella outer membranes permeable, causing Salmonella to be vulnerable to host destruction. [CfaC] (Mus musculus) PubMed

 9923.

The results suggest that tasg1 is a functional stay-green wheat mutant.[tasg1] (Mus musculus) PubMed

 9924.

HO is required for hemin-, auxin-, and nitric oxide-induced lateral root formation in rice.[Heme oxygenase] (Mus musculus) PubMed

 9925.

ALAAT1 and ALAAT2 link mitochondrial glycolate oxidation to the major photorespiratory pathway.[ALAAT1, ALAAT2; Os07g08950 and Os07g42600] (Mus musculus) PubMed

 9926.

OsMYB2 is involved in salt, cold, and dehydration tolerance in rice. [OsMYB2] (Mus musculus) PubMed

 9927.

These results suggest that Plasmodium vivax rhoptry neck protein 2 (RON2) gene has evolved under positive diversifying selection. [RON2] (Mus musculus) PubMed

 9928.

The study performed a screen for BluB point mutants defective in 5,6-dimethylbenzimidazole synthesis. [BluB] (Mus musculus) PubMed

 9929.

electrostatic and steric effects in controlling Pol II transcriptional fidelity [Pol II] (Mus musculus) PubMed

 9930.

Docking of the crystal structure into cryo-electron microscopy maps reveals two loops in CasA that likely have important functions in DNA target binding (CasA). (Mus musculus) PubMed

 9931.

These results suggest that Rad9- and Rad17-independent activation of the ATR-Chk1 signaling pathway also significantly contributes to 5-Fluorouracil tolerance.[CHK1] (Mus musculus) PubMed

 9932.

The aim was also to investigate how the vacuole contributes to control the intracellular calcium availability and the plasma membrane H(+)-ATPase activation in response to glucose.[H(+)-ATPase] (Mus musculus) PubMed

 9933.

RL14 encodes a 2OG-Fe (II) oxygenase family protein. Mutants show a phenotype of leaf rolling. (Mus musculus) PubMed

 9934.

saFabI is capable of efficiently reducing branched-chain fatty acid precursors. (Mus musculus) PubMed

 9935.

Transglutaminase 1 was expressed in synaptic endings of cultured telencephalic neurons. beta-actin was identified as a substrate. TGM1 stabilizes the actin cytoskeleton by cross-linking. TGM1. (Mus musculus) PubMed

 9936.

Trypanosoma brucei sphingolipid Delta4-desaturase (SLdes) was capable of desaturating endogenous sphingolipids at levels comparable to those found in Schyzosaccharomyces pombe SLdes.[SLdes] (Mus musculus) PubMed

 9937.

These results indicate that unphosphorylated RcsB plays an active role for integrating environmental signals and that RcsB phosphorylation acts as a key switch between planktonic and sessile life-styles in S. typhimurium.[RcsB] (Mus musculus) PubMed

 9938.

These results indicate that unphosphorylated RcsB plays an active role for integrating environmental signals and that RcsB phosphorylation acts as a key switch between planktonic and sessile life-styles in S. typhimurium.[RcsB] (Mus musculus) PubMed

 9939.

oxidation of beta-D-glucose by the enzyme glucose oxidase [glucose oxidase] (Mus musculus) PubMed

 9940.

The results suggest that cathepsin L, rather than cathepsin B, is essential to the survival of Trypanosoma brucei and an appropriate drug target.[cathepsin L] (Mus musculus) PubMed

 9941.

These observations suggest that recombinant Bm33 stimulates macrophages to induce Th1 response and does not promote apoptosis.[Bm33] (Mus musculus) PubMed

 9942.

Conditional ablation of Toxoplasma gondii SORTLR disrupts rhoptry and microneme biogenesis, inhibits parasite motility, and blocks both invasion into and egress from host cells.[SORTLR] (Mus musculus) PubMed

 9943.

dUTP incorporation into DNA is a major source of AP sites that cause high genetic instability in the absence of base excision repair factors and Rad17-Mec3-Ddc1 (9-1-1) checkpoint clamp in yeast.[Rad17-Mec3-Ddc1] (Mus musculus) PubMed

 9944.

Mps3 physically associates with all three of these large RFC complex subunits [Htz1][Mps3] (Mus musculus) PubMed

 9945.

Modest reduction in Rad53 activity can impact the activation of the ribonucleotide reductase catalytic subunit Rnr1 following stress.[Rnr1, RAD53] (Mus musculus) PubMed

 9946.

Report novel liposome gel based formulations for intravaginal delivery of the recombinant HIV-1 envelope protein CN54gp140. (Mus musculus) PubMed

 9947.

the influence of alpha-toxin (Hla) during USA300 infection of human leukocytes [Hla] (Mus musculus) PubMed

 9948.

crystal belonged to space group I222 or I2(1)2(1)2(1), with unit-cell parameters a = 184.2, b = 286.4, c = 327.7 A. The asymmetric unit may contain six to ten CheA-CheW molecules[CheA and CheW] (Mus musculus) PubMed

 9949.

structural basis for the Slm1-PH domain (Slm1-PH) specificity [Slm1] (Mus musculus) PubMed

 9950.

Recent applications of biophysical methods to the study of RNR have revealed the importance of oligomeric state to overall enzyme activity and suggest that unprecedented subunit configurations are in play.[RNR Ia] (Mus musculus) PubMed

 9951.

structural and functional study of Salmonella typhimurium D-cysteine desulfhydrase [DcyD] (Mus musculus) PubMed

 9952.

crystals of UDP-galactopyranose mutase contained four molecules per asymmetric unit and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 127.72, b = 134.30, c = 173.84 A[UDP-galactopyranose mutase: AJ871145.2] (Mus musculus) PubMed

 9953.

Data from models of hyperactive bladder suggest that ASIC3 is involved in ATP release from bladder mucosa stimulated by stretch/acid; ASIC3 is expressed in throughout detrusor and bladder mucosa. [ACCN3; acid-sensing ion channel 3; ASIC3] (Mus musculus) PubMed

 9954.

The ERES region regulator Ralp3 is an important serotype-specific transcriptional regulator for virulence and metabolic control [Ralp3] (Mus musculus) PubMed

 9955.

This study showed that Ply released by autolysis cannot reassociate with intact cells, suggesting that there is a Ply export mechanism that is coupled to cell wall localization of the protein.[Ply] (Mus musculus) PubMed

 9956.

Immunolabeling located Malonyl-CoA:acyl-carry protein transacylase encoded by the fabD gene in the apicoplast organelle in coccidial sporozoites.[fabD] (Mus musculus) PubMed

 9957.

Immunolocalization experiments revealed that TgPSD1 resides in the dense granules of T. gondii and is also found in the parasitophorous vacuole of replicating parasites.[PHOSPHATIDYLSERINE DECARBOXYLASE] (Mus musculus) PubMed

 9958.

The salB mutant displayed reduced viability and anomalous cell division, and these phenotypes were exacerbated in a gelE salB double mutant [salB] (Mus musculus) PubMed

 9959.

This finding verified that Rim15p-mediated entry into quiescence plays pivotal roles in the inhibition of ethanol fermentation. [Rim15p] (Mus musculus) PubMed

 9960.

MTM-1, a PI 3-phosphatase that antagonizes the activities of PIKI-1 and VPS-34 by down-regulating phosphatidylinositol 3-phosphate on phagosomes.[Vps-34, PIKI-1] (Mus musculus) PubMed

 9961.

Lack of GapC reduces adhesion of S. aureus H330 to bovine mammary epithelial cells. [GapC] (Mus musculus) PubMed

 9962.

Bmr2 (Brown midrib2) is under auto-regulatory control, as reduced 4-coumarate:CoA ligase (4CL) activity results in over-expression of the defective gene. [Bmr2;4CL] (Mus musculus) PubMed

 9963.

EndoS is complementary to other known endoglycosidases (EndoA, EndoH) used for current protein remodeling [EndoS] (Mus musculus) PubMed

 9964.

The authors also identified TbVAP, a Trypanosoma brucei protein whose knockdown by RNAi in procyclic form cells leads to a dramatic reduction in the flagellum attachment zone of endoplasmic reticulum. [VAP] (Mus musculus) PubMed

 9965.

Nit2 is required for efficient initiation of the pathogenicity program of Ustilago maydis. (Mus musculus) PubMed

 9966.

The Giardia Median Body Protein is a ventral disc protein that is critical for maintaining a domed disc conformation during attachment. (Mus musculus) PubMed

 9967.

analysis of conformational preferences of two peptides DYASL and DYA from haemagglutinin of influenza virus and their possible role in the initiation of protein folding (Mus musculus) PubMed

 9968.

Proteomic screening confirms a lower phosphoprotein Akt/Akt ratio in synaptosomes from HIV/gp120 transgenic mice compared to the wild type, suggesting inactivation of the neuroprotective pathway in the HIV/gp120 transgenic brain. (Mus musculus) PubMed

 9969.

Purification and characterization of lipoxygenase from aromatic and non-aromatic rice (Oryza sativa L.) [lipoxygenase] (Mus musculus) PubMed

 9970.

These results reveal a number of unusual features of the SUB1 substrate binding cleft, including a requirement to interact with both prime and non-prime side residues of the substrate recognition motif.[SUB1] (Mus musculus) PubMed

 9971.

analysis of Pseudomonas cepacia lipase--mediated transesterification reactions of hydrocinnamates (Mus musculus) PubMed

 9972.

analysis of entrapment of Sorghum root oxalate oxidase into polyvinyl alcohol membrane [oxalate oxidase] (Mus musculus) PubMed

 9973.

SdrE recruitment of complement regulatory protein factor H likely provides a survival advantage for S. aureus by negatively affecting the formation of complement activating complexes, thereby dampening the host immune response. (Mus musculus) PubMed

 9974.

LsrR-mediated quorum sensing controls invasiveness of Salmonella typhimurium by regulating SPI-1 and flagella genes. [LsrR] (Mus musculus) PubMed

 9975.

role of autophosphorylation of EhC2PK in regulating erythrophagocytosis [C2PK] (Mus musculus) PubMed

 9976.

Mir-17-92 (Mirc1) cluster and Mir-106b-25 (Mirc3) cluster miRNAs possibly functionally cooperate in regulating spermatogonial development. (Mus musculus) PubMed

 9977.

Cdc73 C-domain probably constitutes a protein interaction surface that functions with Rtf1 in coupling the Paf1 complex [Cdc73][Paf1] (Mus musculus) PubMed

 9978.

hydrolytic and transglycosylation activity of recombinant Endo-D and its selected mutant [Endo-D] (Mus musculus) PubMed

 9979.

Herein, the authors carried out extensive analysis of Fur-regulated promoters and identified a 7-1-7 motif with dyad symmetry (5'-TAATAATnATTATTA-3'), which functions as the Fur box core sequence of Helicobacter pylori.[fur] (Mus musculus) PubMed

 9980.

Nbp2p is conserved regulator of fungal Ptc1p phosphatases and is involved in multiple signaling pathways [Ptc1, Nbp2] (Mus musculus) PubMed

 9981.

Microarray analysis indicates that podJ1 affects the expression of at least 129 genes, the majority of which correspond to observed mutant phenotypes.[podJ1] (Mus musculus) PubMed

 9982.

Nbp2p is conserved regulator of fungal Ptc1p phosphatases and is involved in multiple signaling pathways [Nbp2] (Mus musculus) PubMed

 9983.

AQP2, renders cells sensitive to both melarsoprol and pentamidine and that loss of AQP2 function could explain cases of innate and acquired drug resistance. (Mus musculus) PubMed

 9984.

the interaction between alpha-catulin and alpha-dystrobrevin is evolutionarily conserved in C. elegans and mouse muscles and strongly suggests that this interaction contributes to the integrity of the dystrophin complex (Mus musculus) PubMed

 9985.

Study confirms the alarming levels of antibiotic resistance associated with the degree of gastric inflammation and cagA gene carriage in H. pylori strains in Pakistan. (Mus musculus) PubMed

 9986.

residue in PCNA that is essential to support destruction of all CRL4(Cdt2) substrates [CRL4(Cdt2)] (Mus musculus) PubMed

 9987.

The cAMP-CRP complex activates ideV transcription in vitro. [ideV] (Mus musculus) PubMed

 9988.

Nse5 is important for vital interactions between components within the Smc5/6 complex, and for its functionality during replication stress [Smc5][Smc6][NSE5] (Mus musculus) PubMed

 9989.

Rtt106 deposits H3-H4 heterotetramers onto DNA [Rtt106] (Mus musculus) PubMed

 9990.

Phase variation in contingency genes Cj0045 and Cj0170 strongly associates with colonization and disease in mice. [Cj0045] (Mus musculus) PubMed

 9991.

Toxopalsma gondii formin 3 is an actin nucleator dispensable for tachyzoite growth and motility. (Mus musculus) PubMed

 9992.

A heterologous expression system was used to evaluate activation of BlaR1, a sensor/signal transducer protein of Staphylococcus aureus with a central role in resistance to beta-lactam antibiotics.[BlaR1] (Mus musculus) PubMed

 9993.

Orthologues of AcuK and AcuM, are present in a wide range of fungi and the CCGN7CCG motif is present in the 5' of many genes involved in gluconeogenesis indicating a fundamental role for these transcription factors in fungal carbon metabolism.[AcuK, AcuM] (Mus musculus) PubMed

 9994.

High light triggers RpaB de-phosphorylation whic affects key step of the NblS-RpaB signal transduction pathway. [RpaB] (Mus musculus) PubMed

 9995.

OsHsp17.0 and OsHsp23.7 play an important role in rice acclimation to salt and drought stresses and are useful for engineering drought and salt tolerance rice.[Hsp17.0, Hsp23.7] (Mus musculus) PubMed

 9996.

This work employed density functional theory to study the recharging of the active site with protons and electrons through the series of reaction intermediates based on nitrogen monoxide [Fe(II)-NO+, Fe(II)-NO., Fe(II)-NO-, and Fe(II)-HNO]. (Mus musculus) PubMed

 9997.

seven sites on Pah1p that are phosphorylated by Pho85p-Pho80p [Pho85p][Pho80p][Pah1p] (Mus musculus) PubMed

 9998.

role of LytA in extracellular space during autolysis [LytA] (Mus musculus) PubMed

 9999.

structure and function of NFP protein [NFP] (Mus musculus) PubMed

 10000.

the first eukaryotic UGM structures from Aspergillus fumigatus [UGM] (Mus musculus) PubMed

 10001.

OsDOG has a novel function in regulating gibberellin homeostasis and in negative maintenance of plant cell elongation in rice(OsDOG). (Mus musculus) PubMed

 10002.

UreR is active as a dimer and dimerization occurs within the first 180 residues. [UreR] (Mus musculus) PubMed

 10003.

This result suggests that PHIST/CVC-81(95) is essential for survival of these malaria parasites.[PHIST/CVC-81(95)] (Mus musculus) PubMed

 10004.

These results imply that a basic helix-loop-helix transcription factor is likely to be involved in the regulation of the OsChia4a expression in a jasmonic acid-dependent manner.[OsChia4a] (Mus musculus) PubMed

 10005.

Oxidative stress response in ird11 seems to be affected by glucose signaling in a manner different from that caused by glucose deprivation.[ird11] (Mus musculus) PubMed

 10006.

CMV2b binds both microRNAs (miRNAs) and small interfering RNAs (siRNAs) in vivo [CMV2b] (Mus musculus) PubMed

 10007.

The rice transcription factor IDEF1 directly binds to iron and other divalent metals for sensing cellular iron status. [IDEF1] (Mus musculus) PubMed

 10008.

The RDE-10/RDE-11 complex is essential for the amplification of RNAi in C. elegans by promoting secondary siRNA accumulation. [RED-10] (Mus musculus) PubMed

 10009.

our results indicate a broad role for HENN-1 in both endogenous and exogenous gene silencing pathways and provide further insight into the mechanisms of HEN1 substrate discrimination and the diversity within the Argonaute family (Mus musculus) PubMed

 10010.

This work identifies spe-44 as a critical regulator of sperm-specific transcription in the C. elegans germline (Mus musculus) PubMed

 10011.

The authors show that the expression of genes for lignocellulose degradation are controlled by the orthologous Trichoderma reesei protein methyltransferase LAE1.[LAE1] (Mus musculus) PubMed

 10012.

miR156 controls apical dominance and floral transition in switchgrass by suppressing its target SPL genes.[miR156] (Mus musculus) PubMed

 10013.

Serine 2 phosphorylation of Rpb1 is dispensable for general transcription in fission yeast but strongly affects transcription reprogramming and cell differentiation in response to environmental cues.[Rpb1] (Mus musculus) PubMed

 10014.

Arginine 66 but not histidine 99 in H. pylori Fur is required for the regulatory function of the Fur protein in the acid adaptation mechanism of the bacterium.(Fur ) (Mus musculus) PubMed

 10015.

tRNA modification in the bacterial MnmEG pathway [MnmE][MnmG] (Mus musculus) PubMed

 10016.

The alpha-hemolysin binding to ADAM10 upregulates the receptor's metalloprotease activity on endothelial cells, causing vascular endothelial-cadherin cleavage and concomitant loss of endothelial barrier function. (Mus musculus) PubMed

 10017.

The effects of transgenic Lr34 with specific reference to how expression levels affect resistance, were studied.[Lr34] (Mus musculus) PubMed

 10018.

The analysis of APX, PGD1 and R1G1B gene promoters in various organs and tissues of transgenic rice plants for three homozygous generations, is reported.[APX, PGD1, R1G1B] (Mus musculus) PubMed

 10019.

The role of PpCESA5 in the development of P. patens was investigated by targeted mutagenesis.[ppCESA5] (Mus musculus) PubMed

 10020.

Inactivation of either snoaL2 or snoaW resulted in accumulation of two nonhydroxylated metabolites, nogalamycinone and a novel anthracycline 3',4'-demethoxy-nogalose-nogalamycinone. [SnoaW, SnoaL2] (Mus musculus) PubMed

 10021.

Data showed that MSRA was intrinsically more active with unfolded proteins regardless of MetO availability. [MSRA] (Mus musculus) PubMed

 10022.

PEX13.2, like the PEX13.1 previously described, is associated with glycosomes and that its depletion by RNA interference affects the biogenesis of the organelles and viability of trypanosomes (Mus musculus) PubMed

 10023.

CPK12 functions in multiple signaling pathways, positively regulating salt tolerance and negatively modulating blast resistance.[CPK12] (Mus musculus) PubMed

 10024.

APO2 suppresses the transition from inflorescence meristem to floral meristem through interaction with APO1. [APO2] (Mus musculus) PubMed

 10025.

The single Sco2951 and the double Sco2951 Sco5261 mutants display a strong reduction in the production of the polyketide antibiotic actinorhodin.[Sco2951, Sco5261] (Mus musculus) PubMed

 10026.

These results assign novel functions to both the C-terminal domain of Fcj1 and the TOB/SAM complex.[Fcj1] (Mus musculus) PubMed

 10027.

Disruption of rsbN causes precocious sporulation and biochemical experiments demonstrate that RsbN functions as a sigma(BldN) -specific anti-sigma factor.[RbsN, BldN] (Mus musculus) PubMed

 10028.

We determined the three-dimensional structure of the PHD finger of the rice Siz/PIAS-type SUMO ligase, OsSiz1, by NMR spectroscopy. [OsSiz1] (Mus musculus) PubMed

 10029.

OsbZIP52/RISBZ5 could function as a negative regulator in cold and drought stress environments.[OsbZIP52] (Mus musculus) PubMed

 10030.

CYP97A4 plays a role in alpha-carotene hydroxylation in rice, and knock-out of the gene reduced lutein and increased alpha-carotene, contributing to sensitivity to intense light.[CYP97A4] (Mus musculus) PubMed

 10031.

Overexpression of rubisco activase leads to a decrease in rubisco content, possibly due to post-transcriptional mechanisms.[rubisco activase] (Mus musculus) PubMed

 10032.

SAP8 has been shown for the first time to play a prominent role in biofilms.[SAP8] (Mus musculus) PubMed

 10033.

The results suggest that MoCRC1, a carnitine-acylcarnitine carrier protein, plays vital roles in appressorium-mediated infection and is essential for pathogenesis of M. oryzae(MoCRC1). (Mus musculus) PubMed

 10034.

formate ion was found bound to TRAP identically in all four molecules in the asymmetric unit[ TRAP ] (Mus musculus) PubMed

 10035.

Through this mechanism, horizontal transfer of sopE can enhance the fitness of Salmonella typhimurium, resulting in its significantly increased abundance in the feces. (Mus musculus) PubMed

 10036.

first crystal structure of an intact QSOX enzyme, derived from a trypanosome parasite [QSOX] (Mus musculus) PubMed

 10037.

Two crystal forms of inner membrane complex subcompartment protein 1 belonging to space groups P4(1)32 or P4(3)32 and P2(1)2(1)2(1) diffracted to 2.05 and 2.1 A resolution, respectively[inner membrane complex subcompartment protein 1] (Mus musculus) PubMed

 10038.

Phylogenetic analysis confirmed the three vasa-like genes-termed Smvlg1, Smvlg2, and Smvlg3-were members of the Vasa/PL10 DEAD-box subfamily.[Smvlg1, Smvlg2, and Smvlg3] (Mus musculus) PubMed

 10039.

The N-terminal domain determines the pH-dependent oligomerization characteristic, and C-terminal domain forms a stable dimer, which contributes to the dimerization of the matrix 1 (M1) protein. [matrix 1 protein] (Mus musculus) PubMed

 10040.

PSTOL1 acts as an enhancer of early root growth, thereby enabling plants to acquire more phosphorus and other nutrients [PSTOL1] (Mus musculus) PubMed

 10041.

These results implicate SINA4 E3 ubiquitin ligase in the turnover of SYMRK and provide a conceptual mechanism for its symbiosis-appropriate spatio-temporal containment.[SINA4] (Mus musculus) PubMed

 10042.

targets for oxidation by the Escherichia coli adaptive response protein AlkB [AlkB] (Mus musculus) PubMed

 10043.

Data identify Spc105 as a key target of the Mps1 kinase and show that the opposing activities of Mps1 and PP1 regulate the kinetochore localization of the Bub1 protein. [protein phosphatase 1 (PP1); Spc105; Mps1; Bub1] (Mus musculus) PubMed

 10044.

P25 pathogenicity factor is involved in virus pathogenicity in sugar beet and suggest suppression of resistance response.[P25 pathogenicity factor ] (Mus musculus) PubMed

 10045.

transcriptomic profiling of OsTEF1 revealed that mutation in the transcription elongation factor differentially regulates the expression of more than 100 genes with known function and finely regulates tillering process in rice. [OsTEF1] (Mus musculus) PubMed

 10046.

Postanaphase microtubule generation is predominantly stimulated by the augmin/gamma-tubulin machinery in moss.[Augmin] (Mus musculus) PubMed

 10047.

SHAT1 affects seed shattering. Expression of SHAT1 in the abscission zone was positively regulated by the trihelix transcription factor SH4. [SHAT1; SH4] (Mus musculus) PubMed

 10048.

MADS29 regulates the degradation of the nucellus and nucellar projection by regulating programmed cell death. [MADS29] (Mus musculus) PubMed

 10049.

SSL10, but not SSL7, bound to phosphatidylserine containing liposome, suggesting that SSL10 specifically binds to phosphatidylserine.[SSL10] (Mus musculus) PubMed

 10050.

[KATP channel Kir6.1] Potassium channel Kir6.1 expression level is decreased in aortic smooth muscle models of left ventricular hypertrophy. (Mus musculus) PubMed

 10051.

nitroreductase NtrB has an unusual cold active property [NtrB] (Mus musculus) PubMed

 10052.

These results demonstrate that the dprB product plays important roles affecting inter- and intragenomic recombination.[dprB] (Mus musculus) PubMed

 10053.

This analysis supports a model in which the repeats direct the catalytic AM domain of Atl to the septum, where it can optimally perform the final step of cell division.[Atl] (Mus musculus) PubMed

 10054.

we describe a glucose dependent interaction between Mig2 and Ups1. [Mig2, Ups1] (Mus musculus) PubMed

 10055.

The transmembrane domain of a beta-barrel protein, OmpA, in mixtures of lipids of different tail lengths under conditions of negative hydrophobic mismatch, was simulated.[OmpA] (Mus musculus) PubMed

 10056.

[vp466] VP466 protein was shown to be able to bind host Rab6 protein and increase its GTPase activity in vivo and vitro (Mus musculus) PubMed

 10057.

This is the first report of direct identification of a ComR/ComS pheromone.[ComS, ComR] (Mus musculus) PubMed

 10058.

Schizosaccharomyces pombe homologs of the Saccharomyces cerevisiae mitochondrial proteins Cbp6 and Mss51 function at a post-translational step of respiratory complex biogenesis. [Cpb6, Mss51] (Mus musculus) PubMed

 10059.

OsSCAMP1 is degraded in the lytic vacuole in ubiquitination-independent manner (OsSCAMP1). (Mus musculus) PubMed

 10060.

a plasmin-like protease similar if not identical to plasmin plays a role in follicle rupture during ovulation in the medaka [plasmin] (Mus musculus) PubMed

 10061.

NAL1 is probably synonymous with qFLW4, a major QTL for flag leaf width. The functional difference between the two alleles was due to alternative splicing. (Mus musculus) PubMed

 10062.

The V1 insertion defines a VP2-driven endosomal enlargement of the channel as an essential structural rearrangement performed by the MVM virion to infect.[VP2] (Mus musculus) PubMed

 10063.

STATc is the kinase that activates a nonmetazoan STAT gives insights into the evolution of phosphotyrosine-SH2 domain signaling (Mus musculus) PubMed

 10064.

The study provides in vitro biochemical evidence that wciN gene encodes an alpha-1,3-galactosyltransferase. [alpha-1,3-galactosyltransferase] (Mus musculus) PubMed

 10065.

During prolonged infection, hBD3 was subsequently downregulated by the Helicobacter pylori virulence determinant CagA.[CagA] (Mus musculus) PubMed

 10066.

A role for the Xac-LOV protein in the pathogenic process, is reported.[Xac-LOV] (Mus musculus) PubMed

 10067.

The role of the vpe operon encoding an EII complex of the phosphotransferase system in carbohydrate metabolism and virulence of uropathogenic E. coli is reported.[vpe] (Mus musculus) PubMed

 10068.

data indicate that Coli Surface Antigen 23 (CS23) is a new member of the diverse adhesin repertoire used by enterotoxigenic Escherichia coli strains.[CS23] (Mus musculus) PubMed

 10069.

Mouse hepatitis virus Ns2 cleaves 2',5'-oligoadenylate, the product of 2',5'-oligoadenylate synthetase, to prevent activation of the cellular endoribonuclease RNase L and consequently block viral RNA degradation.[NS2] (Mus musculus) PubMed

 10070.

These results suggest that cycles of phosphorylation and dephosphorylation of Etp, as well as Etk, are involved in the formation of group 4 capsule.[Etk, Etp] (Mus musculus) PubMed

 10071.

This study showed that the activity of EndoSe leads to an antiphagocytic function and may thus be a contributory factor to immune evasion of S. equi, vaccination with EndoSe protected agains streptococcal infection.[EndoSe] (Mus musculus) PubMed

 10072.

Although TcsC plays a role in the adaptation of A. fumigatus to hypoxia, it seems to be dispensable for virulence.[TcsC] (Mus musculus) PubMed

 10073.

Histamine reduced the alpha-CD3-induced interferon-gamma (IFN-gamma) production of CD4+ cells via the histamine H-receptor.[alpha-CD3] (Mus musculus) PubMed

 10074.

Presented is a high-resolution crystal structure of FKBP12 at 1.3 A resolution. [FKBP12] (Mus musculus) PubMed

 10075.

These results identify Panton Valentine leukocidin as the predominant secreted factor for triggering inflammasome activation in human macrophages and demonstrate how macrophages orchestrate inflammation in the lung.[Panton Valentine leukocidin] (Mus musculus) PubMed

 10076.

This study used a fliC deletion mutant of the O113:H21 STEC strain 98NK2 (98NK2DeltafliC) to show that invasion of colonic epithelial cells is heavily dependent on production of flagellin, even though adherence to the cells was enhanced in the mutant.[fli (Mus musculus) PubMed

 10077.

Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK [mir625] (Mus musculus) PubMed

 10078.

High concentrations of alpha-linolenic acid in the culture medium have a detrimental effect on Synechocystis cells and that this effect is dependent on the intracellular Aas (acyl-acyl carrier protein synthetase) dependent activation of fatty acids. [Aas] (Mus musculus) PubMed

 10079.

Loss of secreted vIL-8 resulted in highly reduced disease and tumor incidence in animals infected with vDeltaMetvIL-8 by the intra-abdominal route.[vIL-8] (Mus musculus) PubMed

 10080.

Hydrogen peroxide may enhance the activity of PKG Ialpha-dependent vasodilatation via increased dimerization of the enzyme. (Mus musculus) PubMed

 10081.

The gas-phase thermochemical properties have been measured and calculated for a series of AlkA purine substrates (7-methyladenine, 7-methylguanine, 3-methyladenine, 3-methylguanine, purine, 6-chloropurine, xanthine). [AlkA] (Mus musculus) PubMed

 10082.

The levels of the parasite-derived histamine-releasing factor translationally controlled tumor protein (TCTP)in patients with severe malaria and its relationship to basophil activation are reported.[TCTP] (Mus musculus) PubMed

 10083.

IBF1 as a suppressor could inhibit the brown pigmentation of rice hull furrows.[IBF1] (Mus musculus) PubMed

 10084.

EspH induces actin polymerization at the bacterial attachment sites. (Mus musculus) PubMed

 10085.

The LXR4 protein was heterologously expressed, and the purified protein showed high specificity for L-xylo-3-hexulose. [lxr4] (Mus musculus) PubMed

 10086.

HA70/C can recognize both alpha2-3- and alpha2-6-sialylated oligosaccharides, and it has a higher affinity for alpha2-3-sialylated oligosaccharides [HA70] (Mus musculus) PubMed

 10087.

"similar to nothepsin" expression is unique to the liver of adult females and is sex steroid-dependent;sexual dimorphic expression suggests activity of this protein is regulated by the steroid environment of laying hens and is adapted for inclusion in the (Mus musculus) PubMed

 10088.

These results indicate that the VacA i-region is an important determinant of VacA effects on human T cell function.(vacA) (Mus musculus) PubMed

 10089.

This study showed that YghG is required for assembly of the GspD(beta) secretin and thus function of the type II secretion system beta.[YghG] (Mus musculus) PubMed

 10090.

This study evaluated the type 1 pilus-dependent and -independent effects that contribute to the virulence attenuation of a UPEC qseC deletion mutant in a murine model of experimental urinary tract infection.[QseB; QseC] (Mus musculus) PubMed

 10091.

[ACAA2] SNP(HM537015:g.2982T>C) located in the 3' UTR associated with increased milk yield in Chios breed (Mus musculus) PubMed

 10092.

Together, these results suggest a novel immune-evasion mechanism whereby the HSV-1 LAT (latency-associated transcript) increases the number of HSV-1 Ag-positive DCs in latently-infected TG, and interferes with DC phenotypic and functional maturation. (Mus musculus) PubMed

 10093.

n vivo and in vitro analyses revealed that RpaB and not RpaA could specifically bind to the kaiBC promoter, possibly repressing transcription during subjective night. [RpaB] (Mus musculus) PubMed

 10094.

dna recognition by CcrM [CcrM] (Mus musculus) PubMed

 10095.

These in vivo experiments reveal that, although the benefit shiga-toxin producing E. coli (STEC) gains from urease expression is modest and not absolutely required for colonization, urease can contribute to the pathogenicity of STEC.[ure] (Mus musculus) PubMed

 10096.

although EmrE multidrug transporter proteins are able to form parallel dimers, an antiparallel organization of the subunits in the dimer is preferred (Mus musculus) PubMed

 10097.

Tight control of ParA filament dynamics is essential for proper segregation.[ParA] (Mus musculus) PubMed

 10098.

The isolation and characterization of mannose-1-phosphate guanyl transferase (MPG1) from salt tolerant rice are reported.[MPG1] (Mus musculus) PubMed

 10099.

These results suggest that yellow stripe 1-like 16 (YSL16) plays a role in the allocation of iron(III)-deoxymugineic acid via the vascular bundles.[YSL16] (Mus musculus) PubMed

 10100.

No significant enhancement in MSP1(42) specific antibody titers was observed for any conjugate as compared to the formulated monomer or dimer.[MSP-1] (Mus musculus) PubMed

 10101.

The authors show that APH-2 is dispensable for the establishment of an efficient infection and persistence in a rabbit animal model.[APH-2] (Mus musculus) PubMed

 10102.

[complement control protein] Vaccinia virus complement control protein's inhibitory activities toward bovine complement result from increased binding to bovine complement C3b and is more complement-specific than viral smallpox inhibitor protein SPICE. (Mus musculus) PubMed

 10103.

Seg1/Sle1 controls eisosome assembly and shape, which also involves Pil1 and Lsp1 [Sle1, Pil1, Lsp1] (Mus musculus) PubMed

 10104.

Collectively, our data suggest that sigma(S) likely serves dual functions within the Staphylococcus aureus cell, protecting against both cytoplasmic and extracytoplasmic stresses. (Mus musculus) PubMed

 10105.

Spatial localization of RamS is the key determinant for its subsequent conversion to SapB.[SapB] (Mus musculus) PubMed

 10106.

The study uses large-scale molecular dynamics simulations to compute the redox potentials of the 10 hemes of MtrF in aqueous solution. [MtrF] (Mus musculus) PubMed

 10107.

CkiA is an essential casein kinase I required for delivery of amino acid transporters to the plasma membrane. [CkiA] (Mus musculus) PubMed

 10108.

targeting of ISP4 to the IMC membranes is dependent on residues predicted for palmitoylation but not myristoylation. [ISP4] (Mus musculus) PubMed

 10109.

The PbHAD32 hydrolase plays a role in adherence of conidia to epithelial lung cells. {PbHAD32] Read More: http://informahealthcare.com/doi/full/10.3109/13693786.2011.619583e (Mus musculus) PubMed

 10110.

Staphylothrombin activity generated by S. aureus leads to fibrin deposition and subsequent platelet trapping. (Mus musculus) PubMed

 10111.

region of 4579 bp containing corneodesmosin was shown to contain two exons separated by one intron and spanning 3683 bp[corneodesmosin] (Mus musculus) PubMed

 10112.

Characterization of the M32 metallocarboxypeptidase from Trypanosoma Brucei, substrate specificities and comparison with its orthologue in T. cruzi. [TcMCP-1] (Mus musculus) PubMed

 10113.

This study provides the first experimental insight into the extent of the AdpA regulon, indicating that many genes are under the direct control of AdpA. [AdpA] (Mus musculus) PubMed

 10114.

femA expression in high-level MRSA (non-beta-lactamase-producing) was higher than in low-level MRSA & MSSA. The femA regulating gene may lie in the 250 bp upstream sequence in MRSA. High-level expression of femA is essential for high-level MRSA. femA (Mus musculus) PubMed

 10115.

The crystal structure of a putative general stress protein(XacGSP)was determined to 2.5 A resolution. [general stress protein(XacGSP)] (Mus musculus) PubMed

 10116.

Mlp24 is a chemoreceptor for multiple amino acids, which were previously shown to stimulate the expression of several virulence factors, implying that taxis toward a set of amino acids plays critical roles in pathogenicity of Vibrio cholerae.[Mlp24] (Mus musculus) PubMed

 10117.

The crystal structures of S. aureus peptide deformylase in complex with the four inhibitors were determined at resolutions of 1.90-2.30 A. [peptide deformylase] (Mus musculus) PubMed

 10118.

The metal ion-dependent adhesion site motif of the EbpA mediates pilus function in catheter-associated urinary tract infection.[EbpA] (Mus musculus) PubMed

 10119.

Both GNAS1 and PHD2 short interfering RNA support bone regeneration in vivo. (Mus musculus) PubMed

 10120.

The crystal structure of the family 3b carbohydrate-binding module of the cellulosomal multimodular hydrolytic enzyme cellobiohydrolase 9A (Cbh9A) from Clostridium thermocellum has been determined. [cellobiohydrolase 9A] (Mus musculus) PubMed

 10121.

Initiatorin protein is an activation factor of B. mori sperm. (Mus musculus) PubMed

 10122.

Intracellular signaling and cell mechanics using isolated human airway smooth muscle, mouse tracheal responses, and human bronchial responses to characterize TAS2R relaxation in the context of beta(2)AR desensitization.[TAS2R1] (Mus musculus) PubMed

 10123.

Nramp5 is a major transporter of Mn and Cd and is responsible for the transport of Mn and Cd from the external solution to root cells. [ Nramp5 ] (Mus musculus) PubMed

 10124.

Accordingly, the immune adjuvant activity of Fusobacterium nucleatum FomA is TLR2 dependent.[FomA] (Mus musculus) PubMed

 10125.

B5 was required for extracellular enveloped vaccinia virus to induce the formation of actin tails at the surface of infected cells.[B5] (Mus musculus) PubMed

 10126.

A novel NLS of VP19C and its nuclear localization is required for efficient production of HSV-1.[VP19C] (Mus musculus) PubMed

 10127.

HBZ inhibits the HAT activity of p300/CBP through the bZIP domain of the viral protein (HBZ). (Mus musculus) PubMed

 10128.

function and subcellular localization of coronin [Crn-1] (Mus musculus) PubMed

 10129.

the importance of translational control during the Leishmania differentiation process [eIF2alpha] (Mus musculus) PubMed

 10130.

There is considerable heterogeneity among Helicobacter pylori strains in salt-regulated CagA expression, and these differences are attributable to variation in a specific DNA motif upstream of the cagA transcriptional start site.[CagA] (Mus musculus) PubMed

 10131.

The results showed that amino acids (31-33) from NS3 were important for the interaction with detergent micelles, which was similar to the finding in the study of protease from Dengue virus. This region may serve as an anchoring site to stabilized NS3 protease domain on the membrane.[NS3] (Mus musculus) PubMed

 10132.

AMT1, like its ortholog in yeast, is the predominant PRMT gene in F. graminearum and plays a role in hyphal growth, stress responses, and plant infection [AMT1] (Mus musculus) PubMed

 10133.

In silico mutagenesis and modeling analysis suggest that the studied genetic variations lead to conformational changes in the Na(+)/galactose transporter either by structure destabilization or by formation of unnecessary interaction within the core structure (Na(+)/galactose transporter). (Mus musculus) PubMed

 10134.

Os11N3 is directly upregulated by TalC and identify a TalC DNA target box within the Os11N3 upstream sequence. [Os11N3] (Mus musculus) PubMed

 10135.

functional and structural analyses of the TTHB023(PfmR) protein; the center of the PfmR molecule contains a tunnel-like pocket, which may be the ligand-binding site of this regulator [PfmR] (Mus musculus) PubMed

 10136.

These results suggest that SP0454 contributes to virulence and colonization, which could be explained in part by modulating the expression of other virulence factors, such as psaA in pneumococcal infection.[SP0454] (Mus musculus) PubMed

 10137.

High dose glargine alters the expression profiles of microRNA mirn95 in pancreatic cancer cells (Mus musculus) PubMed

 10138.

Spontaneous water supply to the intramembrane active site of rhomboid proteases is rare, but its availability for catalysis is ensured by an unanticipated active site element, the water-retention site.[GlpG] (Mus musculus) PubMed

 10139.

possible controlling mechanism of nascent chains within the tunnel that leads to chaperone recruitment and the ribosomal protein that serves as docking sites for both TF and SRP, in cotranslational protein targeting [trigger factor] (Mus musculus) PubMed

 10140.

the features of the energy landscape that decide the folding of the protein [phosphoglycerate kinase] (Mus musculus) PubMed

 10141.

these results show that ibeA by itself is able to confer increased H2O2 resistance to E. coli (Mus musculus) PubMed

 10142.

proposed that the C-terminal portion of SltF modulates the interaction with the scaffold protein FlgJ during the assembly process [SltF, FlgJ] (Mus musculus) PubMed

 10143.

We confirm previous reports that SigX is functional and able to activate sigX-dependent gene expression within the competence regulon, and that SigX stability is influenced by the cytoplasmic protease ClpP. (Mus musculus) PubMed

 10144.

From these results, the authors propose a model whereby IcsA self-association facilitates efficient actin-based motility.[IcsA] (Mus musculus) PubMed

 10145.

KlMGA2 transcription was induced by hypoxia and the glucose sensor Rag4 mediated the hypoxic induction of KlMGA2.[KlMGA2, Rag4] (Mus musculus) PubMed

 10146.

FgVelB-deleted (DeltaFgVelB) strains produced fewer aerial mycelia with less pigmentation than those of the wild-type (WT) during vegetative growth.[FgVelB] (Mus musculus) PubMed

 10147.

Progesterone and adipoQ receptor 11 (PAQR11) plays a critical role in heart morphogenesis via ras signaling. (Mus musculus) PubMed

 10148.

stability and binding affinities between the active-site-histidine phosphorylated species of HPr and the EIN [HPr][EIN] (Mus musculus) PubMed

 10149.

The isolation of genetic suppressors that inactivate the Tat quality-control mechanism provides direct evidence for the participation of the Tat translocase in structural proofreading of substrate proteins.[TatA, TatB, TatC] (Mus musculus) PubMed

 10150.

expression and identification of catalytically relevant residues [ClcF] (Mus musculus) PubMed

 10151.

The crystal structure of an active RNA ligase consisting of the C-terminal half of Pnkp (Pnkp-C) and the N-terminal half of Hen1 (Hen1-N) from Clostridium thermocellum, is reported.[Hen1, Pnkp] (Mus musculus) PubMed

 10152.

Electrophysiological analysis of FocA from Salmonella typhimurium, was carried out to characterize the channel properties and assess its specificity toward formate and other possible permeating ions.[FocA] (Mus musculus) PubMed

 10153.

role of residues important to hydrogen peroxide access [KatE] (Mus musculus) PubMed

 10154.

the N-terminal inhibitory extension is the primary mechanosensory regulator of twitchin kinase [twitchin] (Mus musculus) PubMed

 10155.

analysis of CaM docked to a functioning KCNQ K(+) channel (KCNQ2 and KCNQ3) [KCNQ2, KCNQ3] (Mus musculus) PubMed

 10156.

[Dsh1] Dsh1 is required for the colocalization of Dcr1 and RDRC (Mus musculus) PubMed

 10157.

Complementation analyses of Corynebacterium glutamicum DeltamanC with Rv3264c suggested that it is a true homologue of ManC in Mycobacterium tuberculosis.[ManC] (Mus musculus) PubMed

 10158.

Laue crystal structure of Shewanella oneidensis cytochrome c nitrite reductase (Mus musculus) PubMed

 10159.

The function of chloroplast RH3 in maize (Zea mays; ZmRH3) and Arabidopsis (Arabidopsis thaliana; AtRH3) was determined.[ZmRH3] (Mus musculus) PubMed

 10160.

Yeast cells that lack Ywp1 are more adhesive and form thicker biofilms, implying an antiadhesive activity for Ywp1.[Ywp1] (Mus musculus) PubMed

 10161.

S4D mutant protein failed to depolymerize F-actin but weakly bound G-actin and inhibited the exchange of G-actin-bound nucleotide.[S4D, ADF/cofilin, actin] (Mus musculus) PubMed

 10162.

Taken together, these results indicate that mpg1 and mpg2 function together in glycosylation and septum formation.[Mpg2] (Mus musculus) PubMed

 10163.

KAR7 gene plays an integral role in both opposite-sex and unisexual mating.[KAR7] (Mus musculus) PubMed

 10164.

The authors measured cell wall chitin deposition and found a twofold increase in thePIR32 mutant. (Mus musculus) PubMed

 10165.

The TRX domain interacts constitutively with Php4, the GRX domain-Php4 association is both modulated by iron and required for the inhibition of Php4 activity in response to iron repletion.[Grx4, Php4] (Mus musculus) PubMed

 10166.

CKX6 (cytokinin oxidase/dehydrogenase 6) is associated with grain weight in wheat. [CKX6] (Mus musculus) PubMed

 10167.

characterization of ENT4 expressed in Xenopus oocytes: Data suggest ENT4 transports adenine, adenosine, and 2'-deoxyadenosine (not hypoxanthine/AMP); dipyridamole/plant hormone cytokinin inhibit ENT4. [ENT4; equilibrative nucleoside transporter 4] (Mus musculus) PubMed

 10168.

characterization of ENT4 expressed in Xenopus oocytes: Data suggest ENT4 transports adenine, adenosine, and 2'-deoxyadenosine (not hypoxanthine/AMP); dipyridamole/plant hormone cytokinin inhibit ENT4. [ENT4; equilibrative nucleoside transporter 4] (Mus musculus) PubMed

 10169.

Infection with dupA-positive H. pylori increases the overall risk for duodenal ulcer and this evidence was significant in our South-east Indian population. (Mus musculus) PubMed

 10170.

VexH contributed to in vitro antimicrobial resistance and exhibited a broad substrate specificity that was redundant with the VexB, VexD, and VexK RND efflux pumps [vexH] (Mus musculus) PubMed

 10171.

there is a direct interaction between DDX5 and NS5B and DDX5 has two independent NS5B-binding sites [NS5B] (Mus musculus) PubMed

 10172.

YidC1 and YidC2 contribute to cell surface biogenesis and protein secretion and differences in stress sensitivity between the DeltayidC1 and DeltayidC2 mutants stem from a functional difference in the C-termini of these two proteins.[YidC1, YidC2] (Mus musculus) PubMed

 10173.

These results suggest that the endoplasmic reticulum stress taking place in Kloch1-1 cells appears to be the primary cause of the KlMID1 down-modulation and its resulting effects on the expression of calcium homeostasis genes.[KlMID1] (Mus musculus) PubMed

 10174.

evolution and association of Ghd7 with plant height, heading date, and yield [Ghd7] (Mus musculus) PubMed

 10175.

structure and activity of ArcB [ArcB] (Mus musculus) PubMed

 10176.

ZmALMT2 is not involved in maize Al tolerance but, rather, may play a role in mineral nutrient acquisition and transport. [ALMT2] (Mus musculus) PubMed

 10177.

PG deacetylation mechanism likely contributes to Shigella persistence by subverting detection by the host immune system. [SfPgdA] (Mus musculus) PubMed

 10178.

HIV gp120 the third variable loop V3 net charge and flexibility are the two main elements in the co-receptor selection.[HIV gp120] (Mus musculus) PubMed

 10179.

These data indicate that a single tet(M) gene sequence type, most probably transmitted via a Tn916/Tn1545-like transposon, contributes to most of the tetracycline resistance in U. parvum and M. hominis isolates in Tunisia. [tet(M)] (Mus musculus) PubMed

 10180.

The authors demonstrate that the 3'UTR of the GP82 transcript is involved in this developmental regulation, promoting higher expression of the green fluorescent protein (GFP) reporter in metacyclic trypomastigotes than in epimastigotes.[GP82] (Mus musculus) PubMed

 10181.

The Proto-Oncogene Proteins p21(ras)downstream effector pathways in tumorigenesis. (Mus musculus) PubMed

 10182.

Impaired insulin and IGF-1 signaling promotes L-proline metabolism to generate a reactive oxygen species signal for the adaptive induction of endogenous stress defense to extend life span.[Insulin, Igf-1] (Mus musculus) PubMed

 10183.

colloid-like1 plays a role in the reinforcement of BMP4 activity in the medial portion of the 10 most anterior dermomyotomes, thus belonging to the molecular machinery controlling neck muscle development in the chick.[colloid-like1] (Mus musculus) PubMed

 10184.

Crystal structures of ASIC1a-psalmotoxin complexes map the toxin binding site to the extracellular domain and show how toxin binding triggers an expansion of the extracellular vestibule and stabilization of the open channel pore [ASIC1a] (Mus musculus) PubMed

 10185.

The impact of embryonic hypoxia on hypoxia inducible factor 2alpha(HIF-2alpha), VEGF, and its type 2 receptor in 6- and 7-day-old chick embryos are reprorted.[HIF-2alpha] (Mus musculus) PubMed

 10186.

Sma0114 has a conserved active site, binds divalent metal ions such as Mg(2+) and Ca(2+) that are required for phosphorylation, and exhibits micro- to millisecond active-site dynamics similar to those of other receiver domains.[Sma0114] (Mus musculus) PubMed

 10187.

These studies reveal a new virulence-associated function for yersiniabactin (Ybt) that is distinct from iron binding.[Ybt] (Mus musculus) PubMed

 10188.

X-ray structural analysis of Salmonella typhimurium uridine phosphorylase complexed with 5-fluorouracil and molecular modelling of the complex of 5-fluorouracil with uridine phosphorylase from Vibrio cholerae [UPh] (Mus musculus) PubMed

 10189.

analysis of the structure of PII protein variant PII-186N with citrate [PII-186N] (Mus musculus) PubMed

 10190.

Tti2 is required for the folding/stability of the C-terminal FATC and PI3K domains of Tra1 into their functionally active form [Tti2][Tra1] (Mus musculus) PubMed

 10191.

role for the co-chaperone Cpr7 in modulating Hsp90 function [Hsp90][Cpr7] (Mus musculus) PubMed

 10192.

regulation of chromatin structure represents an important layer of control in the highly complex regulation of the FLO11 promoter [FLO11] (Mus musculus) PubMed

 10193.

CRM1, as an export receptor, can also control the composition of nucleoplasmic complexes [CRM1] (Mus musculus) PubMed

 10194.

Dbp2 and Ded1 helicases play redundant roles in TBSV replication. [Dbp2, Ded1] (Mus musculus) PubMed

 10195.

novel insertion mutation of E1/E2 proteins [E1][E2] (Mus musculus) PubMed

 10196.

results suggest that both single mutations HA K154Q and PA L295P are necessary for delayed virus clearance of A/Tennessee/560/09(H1N1) influenza virus in a ferret animal model. [HA, PA] (Mus musculus) PubMed

 10197.

variation of PB1-F2 genes of Influenza A Viruses from Guangzhou during 2009 to 2011 [PB1-F2] (Mus musculus) PubMed

 10198.

the variation and evolution of HA genes [hemagglutinin] (Mus musculus) PubMed

 10199.

structure, primary function, evolution and antigenicity of pandemic A/H1N1/2009 influenza virus HA protein [HA] (Mus musculus) PubMed

 10200.

findings show that Pinhead is an antagonist specific for Admp with a role in establishing the dorsoventral axis of the trunk epidermis in embryos of Ciona intestinalis; Pinhead transcription directly disturbs the action of the Admp enhancer [Pinhead] (Mus musculus) PubMed

 10201.

These results support the positive role of ZmHSP16.9 in response to heat stress in plant.[ZmHSP16.9] (Mus musculus) PubMed

 10202.

OsRbohB shows ROS-producing activity.(OsRbohB) (Mus musculus) PubMed

 10203.

OsTZF1 encodes a cytoplasm-localized tandem zinc finger protein and is regulated by both abscisic acid and phytochrome-mediated light signaling. [TZF1] (Mus musculus) PubMed

 10204.

virulence of C. neoformans strains in mice is not affected by Gat1, but the transcription factor does positively influence the virulence of C. gattii strain [Gat1] (Mus musculus) PubMed

 10205.

have identified a novel metal acquisition system in Candida albicansconsisting of PRA1, a secreted zinc scavenger ("zincophore"), which reassociates with the fungal cell[Pra1] (Mus musculus) PubMed

 10206.

This study investigates the motions of UDP-galactose 4'-epimerase homodimer in both the apo and holo forms, bound to UDP-galactose, UDP-glucose, and the UDP-ketose intermediate. [UDP-galactose 4'-epimerase] (Mus musculus) PubMed

 10207.

The C-terminal domain of the interaction protein A1 plays a key role in RNA binding by the RNA-editing ligase L2 in trans (interaction protein A1, RNA-editing ligase L2). (Mus musculus) PubMed

 10208.

This type of dimeric structure of a peptidase is here reported for the first time.[aspergilloglutamic peptidase] (Mus musculus) PubMed

 10209.

The present work described the open structure of SMG1 in complex with diacylglycerol analogue, which allowed a detailed discussion of the structurally important parts responsible for the unique selectivity of this lipase.[SMG1] (Mus musculus) PubMed

 10210.

MMP 9 metalloproteinase is involved in the pathogenesis of tympanosclerosis. (Mus musculus) PubMed

 10211.

These findings suggest that ROP18 and ROP5 have specifically evolved to block interferon-gamma (IFNgamma)-induced immunity-related GTPases and are unlikely to have effects in species that do not have the IRG system, such as humans (Mus musculus) PubMed

 10212.

ROP5 pseudokinases act as powerful enhancers of ROP18-dependent phosphorylation of IRG (interferon-gamma-inducible immunity-related GTPases) proteins in T. gondii-infected cells. [ROP18; ROP5] (Mus musculus) PubMed

 10213.

virulence of C. neoformans strains in mice is not affected by Gat1, but the transcription factor does positively influence the virulence of C. gattii strain [Gat1] (Mus musculus) PubMed

 10214.

the narrow active-site cleft of O-acetylserine sulfhydrylase from Leishmania donovani allows complex formation with serine acetyltransferases with a range of C-terminal sequences [OASS] (Mus musculus) PubMed

 10215.

8-Bromo-cAMP stimulated alpha-methyl-D-glucopyranoside uptake via Epac and PKA-dependent SGLTs expression and trafficking through cav-1 and F-actin in proximal tubule cells.[F-actin, Epac, PKA, SGLT] (Mus musculus) PubMed

 10216.

subcellular localization, expression pattern, and associations of porcine TIMD4 (Mus musculus) PubMed

 10217.

findings show that the transcriptional regulator, VpsT, requires c-di-GMP binding for subcellular localization and activity [VpsT] (Mus musculus) PubMed

 10218.

the direct interaction between CheA and a chemoreceptor, TM0014,12 from Thermotoga maritima with NMR techniques (Mus musculus) PubMed

 10219.

Prolactin and epidermal growth factor stimulate adipophilin synthesis in HC11 mouse mammary epithelial cells via the PI3-kinase/Akt/mTOR pathway.[EGF] (Mus musculus) PubMed

 10220.

The activity responsible for stimulating RNA annealing was mapped to the C-terminal RNA-binding region of West Nile virus core protein.[core protein] (Mus musculus) PubMed

 10221.

A simian varicella virus mutant lacking ORF A replicated as efficiently as wild-type simian varicella virus in infected Vero cells, indicating that ORF A expression is not essential for in vitro replication.[ORF A] (Mus musculus) PubMed

 10222.

Using single-molecule Forster resonance energy transfer, the study observed individual Escherichia coli DNA polymerase I (Klenow fragment) molecules performing substrate selection. [DNA polymerase I] (Mus musculus) PubMed

 10223.

OsHk6 (histidine kinase 6)is a preferential receptor for isopentenyladenine in rice.[Hk6] (Mus musculus) PubMed

 10224.

Bud4 is involved in septum formation in both hyphae and developing conidiophores, whereas Axl2 is required for the regulation of phialide morphogenesis during conidiation.[Bud4, Axl2] (Mus musculus) PubMed

 10225.

A predicted compact cysteine-rich sequence in the honey bee genome called 'Raalin', was identified.[Raalin] (Mus musculus) PubMed

 10226.

heme release and uptake processes occur via intermediate states characterized by a Tyr(75)-iron-bound form with open conformation of loop L1[HasA] (Mus musculus) PubMed

 10227.

these findings show that the Lancefield Group B carbohydrate is an essential component of the cell wall of Streptococcus agalactiae whose function is reminiscent of that of conventional wall teichoic acids[gbcO] (Mus musculus) PubMed

 10228.

Msn5 controlled subcellular localization of the mitotic exit transcription factor Swi5.[Msn5, Swi5] (Mus musculus) PubMed

 10229.

The corazonin gene and transcript structure in the mosquito Anopheles gambiae is described, its developmental expression, and its role in modulating heart physiology, were examined.[Corazonin] (Mus musculus) PubMed

 10230.

Deletion of A8 or A23, viral early gene expression and DNA replication occurred but intermediate and late gene expression were not detected.[A23] (Mus musculus) PubMed

 10231.

UL31 is an early gene that that harbors a nuclear localization signal sequence at the extreme 32 residues of the C-terminus and preferentially binds to single-stranded DNA.[UL31] (Mus musculus) PubMed

 10232.

HTLV-1 bZIP factor(hbz) requires cellular JunD to upregulate HTLV-1 antisense transcription from the 3' long terminal repeat. [hbz] (Mus musculus) PubMed

 10233.

found that SseL activity lowers autophagic flux and favours intracellular Salmonella replication[ssel] (Mus musculus) PubMed

 10234.

Targeted disruption of OsDRM2 severely impaired de novo methylation and the growth of rice plants in both vegetative and reproductive stages. [DRM2] (Mus musculus) PubMed

 10235.

Ppd-1 in wheat is not important for the feedback loops in the circadian clock. Ppd-1a mutations increase TaFT1 expression. Multiple Ppd-1a introgressions result in earlier flowering. [Ppd1] (Mus musculus) PubMed

 10236.

We report the identification, functional expression, purification, reconstitution and electrophysiological characterization of a novel cation channel (TcCat) from Trypanosoma cruzi (Mus musculus) PubMed

 10237.

These results identify the key residues governing the interactions between AMA1 and RON2 in P. falciparum (Mus musculus) PubMed

 10238.

These findings suggest that SpSsbB may be able to facilitate SpRecA-promoted DNA recombination reactions during natural transformation in S. pneumoniae.[SsbB][RecA] (Mus musculus) PubMed

 10239.

findings show that both SaPI1 gp6 (CpmB) and gp7 (CpmA) are necessary to direct small capsid formation and helper phage interference [CpmA, CpmB] (Mus musculus) PubMed

 10240.

Pbp2 and MreB are required for normal chlamydial cell division. [Pbp2; MreB] (Mus musculus) PubMed

 10241.

The study reports the first crystal structure of a fungal 6-oxopurine phosphoribosyltransferase, the Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with GMP. [hypoxanthine-guanine phosphoribosyltransferase] (Mus musculus) PubMed

 10242.

The deconjugation of Atg8-phosphatidylethanolamine is required for efficient autophagosome biogenesis.[Atg8] (Mus musculus) PubMed

 10243.

rfbE and waaL genes are required for the the resistance of bacteria to moricin.[rfbE;waaL] (Mus musculus) PubMed

 10244.

These results demonstrate that the R-rich motif of P7a is correlated with nuclear and nucleolar localization, viral replication and virus infection.[P7a] (Mus musculus) PubMed

 10245.

study concludes that MC69 is a secreted pathogenicity protein commonly required for infection of two different plant pathogenic fungi, M. oryzae and C. orbiculare pathogenic on monocot and dicot plants, respectively [MC69] (Mus musculus) PubMed

 10246.

Bcr1 is a phosphoprotein that physically interacts with the NDR kinase Cbk1 and undergoes Cbk1-dependent phosphorylation; data uncovered a novel role of the NDR/LATS kinase Cbk1 in the regulation of biofilm development through the control of Bcr1 [BCR1] (Mus musculus) PubMed

 10247.

PBP2 stimulates the glycosyltransferase activity of PBP1A, and PBP1A and PBP2 cooperate to attach newly synthesized peptidoglycan to sacculi. PBP2 has peptidoglycan transpeptidase activity in the presence of active PBP1A. [PBP2; PBP1A] (Mus musculus) PubMed

 10248.

The authors provide the first molecular explanation of carbon source-mediated regulation of Mxr1 activity, whose mechanism involves a post-DNA binding role of 14-3-3.[Mxr1, 14-3-3] (Mus musculus) PubMed

 10249.

study identified 2 paralogous mglur6 genes; apart from expression in the inner nuclear layer of the retina, found expression in retinal ganglion cells and other parts of the brain, suggesting more widespread functions of mGluR6 mediated signaling in the central nervous system [mglur6a, mglur6b] (Mus musculus) PubMed

 10250.

The structure reveals that, in addition to the photolyase-like fold, CryB contains two cofactors only conserved in the CryPro subfamily: 6,7-dimethyl-8-ribityl-lumazine in the antenna-binding domain and a [4Fe-4S] cluster within the catalytic domain (CryB). (Mus musculus) PubMed

 10251.

Study established a physiological role for SCAR phosphorylation in Dictyostelium; the large cytoplasmic pool of SCAR is normally phosphorylated and relatively inactive; SCAR dephosphorylation loosens an intramolecular inhibition, leading to an increase in activity.[SCAR] (Mus musculus) PubMed

 10252.

Study reports the cloning and sequencing of LAMP3 in rainbow trout; predicted trout LAMP3 shares the characteristic features of LAMP family members; expression studies revealed that trout LAMP3 was constitutively expressed in a wide range of lymphoid tissues, at highest levels in the head kidney, liver and spleen, respectively.[LAMP3] (Mus musculus) PubMed

 10253.

For reprogramming, CDKA is necessary for cell cycle progression and that this kinase regulates cell cycle progression and acquisition of new cell characteristics in parallel.[CDKA] (Mus musculus) PubMed

 10254.

The overexpression of VvIAA9 in Arabidopsis thaliana promoted plant growth, including rapid floral transition. (Mus musculus) PubMed

 10255.

study reports the emergence of a novel 2009 A(H1N1) variant possessing a re-emergent HA D222N mutation obtained from patients with severe respiratory illnesses and phylogenetically characterise these D222N mutants with other severe disease-causing variants clustering within a common emerging sub-clade [HA -H1N1] (Mus musculus) PubMed

 10256.

BC2L-C has two distinct domains with unique specificities and biological activities. The N-terminal domain is a novel TNF-alpha-like fucose-binding lectin, while the C-terminal part is similar to a superfamily of calcium-dependent bacterial lectins[BC2L-C] (Mus musculus) PubMed

 10257.

propose balance between Tax and HBZ expression determines outcome of HTLV1 infection;HTLV1 replication and elevated Tax expression drive NFkappaB hyperactivation and trigger senescence;HBZ modulates Tax-mediated viral replication and NFkappaB activation [HBZ] (Mus musculus) PubMed

 10258.

study revealed slyA-EF_3001 locus appears to be autoregulated; 117 genes were differentially regulated in DeltaslyA mutant; in mutant strain, 111 were underexpressed and 6 overexpressed, indicating SlyA functions mainly as an activator of transcription[SlyA] (Mus musculus) PubMed

 10259.

these findings show that rice male reproductive cells secrete the MTR1 protein to control the development of reproductive cells and their adjacent somatic cells, thus providing novel insights into the mechanism of plant male reproductive development. [MRR1] (Mus musculus) PubMed

 10260.

crystal structure of Schizosaccharomyces pombe MCC (a complex of mitotic spindle assembly checkpoint proteins Mad2, Mad3 and APC/C co-activator protein Cdc20), we reveal the molecular basis of MCC-mediated APC/C inhibition and the regulation of MCC assembly [Mad2; Mad3; Cdc20] (Mus musculus) PubMed

 10261.

determined role of general stress-response alternative sigma factors sigma(S) (RpoS) and sigma(B)(SigB) in heat resistance and occurrence of sublethal injuries in cell envelopes of stationary-phase E. coli BJ4 and L. monocytogenes EGD-e cells [sigB and RpoS] (Mus musculus) PubMed

 10262.

human TAB2 and TAB3, ubiquitin-chain sensory proteins involved in NF-kappaB signalling, are directly inactivated by enteropathogenic Escherichia coli NleE, a conserved bacterial type-III-secreted effector responsible for blocking host NF-kappaB signalling [NleE] (Mus musculus) PubMed

 10263.

activation and cellular localization of COT1 are coordinated by dual phosphorylation and interaction with MOB2 [Dbf2-related kinase COT1] (Mus musculus) PubMed

 10264.

prune may regulate Muller gliogenesis through phosphodiesterase-mediated regulation of NM23 family members (prune) (Mus musculus) PubMed

 10265.

Ngn2 together with NeuroM serves as readout to regulate GFRalpha1 expression, which occurs in multiple subtypes of spinal neurons. [NeuroM] (Mus musculus) PubMed

 10266.

These studies show that H-NS is a target for mutations conferring fitness gain that depends on the genetic background as well as on the stage of the stationary phase.[H-NS] (Mus musculus) PubMed

 10267.

This study showed that only that only FtsZ and ZipA are required to generate PBP3-independent peptidoglycan synthesis in wild-type Escherichia coli.[FtsZ; ZipA] (Mus musculus) PubMed

 10268.

These findings suggest that ToxT binds to only two toxboxes within PctxAB, despite the presence of several other potential ToxT binding sites within the promoter.[ToxT] (Mus musculus) PubMed

 10269.

phosphorylation of OsWRKY30 by MAP kinases was crucial in order for OsWRKY30 to perform its biological function. [OsWRKY30] (Mus musculus) PubMed

 10270.

ZFP182 has transcription activation activity in yeast and the C-terminus Leu rich region is required for the trans-activation. Overexpression of ZFP182 led to enhanced tolerance to salt, cold and drought stresses in rice. (Mus musculus) PubMed

 10271.

The key functions of NR is the formation of the signaling nitric oxide molecule in in wheat leaves. [NR] (Mus musculus) PubMed

 10272.

Mutations in maize CAD2 are responsible for maize brown midrib1 (bm1) phenotypes. [CAD2] (Mus musculus) PubMed

 10273.

Authors studied the role of Egfr, spi and pnt in leg development in the beetle Tribolium castaneum and show that Egfr signaling has a more complex role in T. castaneum than in D. melanogaster and is not only required in the distal leg, but is also involved in formation of the medial leg (including femur and tibia). [Spitz (spi), Pointed (pnt)] (Mus musculus) PubMed

 10274.

anabolic ornithine carbamoyltransferase structure presents an open conformation of the enzyme with a relatively flexible orientation of the L-ornithine-binding domain respective to the carbamoyl phosphate-binding domain[ornithine carbamoyltransferase ] (Mus musculus) PubMed

 10275.

plate-shaped crystal of SGR6054 belonged to space group C2, with unit-cell parameters a = 88.53, b = 69.35, c = 77.71 A, beta = 96.63 degrees , and diffracted X-rays to 2.22 A resolution[SGR6054] (Mus musculus) PubMed

 10276.

These results provide genetic information about both swine IL-23 the IL-23 receptor alpha (IL-23Ralpha) and IL-12 receptor beta1 (IL-12Rbeta1), which allows for better understanding of interleukin systems involved in pig immunity.[IL-23Ralpha; IL-12Rbeta1] (Mus musculus) PubMed

 10277.

localization of Psb27 within Photosystem II (PSII) and analysis of its role in biogenesis of PSII; results show that Psb27 binds to and stabilizes unassembled CP43 and also indicate that during the PSII assembly pathway, both proteins bind to the CP47-D1-D2 complex together, forming the monomeric PSII core complex [Psb27] (Mus musculus) PubMed

 10278.

selective reaction catalyzed by utp glucose 1 phosphate uridylyltransferase[utp glucose 1 phosphate uridylyltransferase] (Mus musculus) PubMed

 10279.

Seven zinc-finger transcription factors are novel regulators of the stress responsive gene DREB1B.[ OsDREB1B,Os09g35010] (Mus musculus) PubMed

 10280.

study reports a novelgene, Tillering and Dwarf 1 (TAD1),which encodes a co-activator of the anaphase-promoting complex (APC/C); study demonstrates TAD1 interacts with MOC1, forms a complex with OsAPC10 and functions as a co-activator of APC/C to target MOC1 for degradation in a cell-cycle-dependent manner [TAD1, MOC1] (Mus musculus) PubMed

 10281.

diffraction data were collected to a resolution of 2.0 A from a crystal of casein kinase I-like protein(CKI) belonging to the monoclinic space group C2, with unit-cell parameters a = 108.83, b = 69.60, c = 55.85 A, beta = 109.47 degrees [CKI:GenBank ID BAB92346] (Mus musculus) PubMed

 10282.

ERF922 negatively regulates resistance to Magnaporthe oryzae and salt tolerance. [ERF922(Os01g54890)] (Mus musculus) PubMed

 10283.

TcRBP40 is differentially expressed in metacyclogenesis. Surprisingly, in epimastigotes, it is dispersed in the cytoplasm but is concentrated in the reservosomes, a T. cruzi specific organelle, which suggests a putative new function for this parasite organelle. [TcRBP40] (Mus musculus) PubMed

 10284.

Unprecedented for staphylococcal lipoproteins, FhuD2 was demonstrated to have a discrete, punctate localization on the bacterial surface. (Mus musculus) PubMed

 10285.

The authors show that a synergistic activity of the cytolytic peptide, staphylococcal delta-toxin and the sphingomyelinase beta-toxin enable the phagosomal escape of staphylococci in human epithelial as well as in endothelial cells.[delta toxin & beta toxin] (Mus musculus) PubMed

 10286.

Analysis of 5'-flanking region of Adp has identified several potential binding sites for transcriptional factors related to both adipocyte differentiation and inflammation, highlighting the significance of Adp in energy metabolism. (adp, adipose) (Mus musculus) PubMed

 10287.

the effects of mutations in RecF pathway genes on DNA repair and on conjugational recombination in recC1004 and recC1004 recD backgrounds (Mus musculus) PubMed

 10288.

Rns regulator of Escherichia coli dimerises in vivo and in vitro [Rns] (Mus musculus) PubMed

 10289.

the crystal structure of the rice branching enzyme I (BEI) in complex with maltopentaose at a resolution of 2.2A was determined. (Mus musculus) PubMed

 10290.

H-NOX is a NO sensor and NO/H-NOX regulates phosphorylation of a kinase that transfers phosphate to LuxU[hnoX, luxU] (Mus musculus) PubMed

 10291.

study concluded: 1) the ORF1 protein is not essential for ZfL2-1 retrotransposition in cultured cells; 2) the translation of ORF1 is required for the translation of ORF2; and 3) ORF2 translation probably occurs via suppression of the ORF1 stop codon [ORF1 protein] (Mus musculus) PubMed

 10292.

Evidence showing that a previously uncharacterized transmembrane protein, designated Cholesterol Uptake Protein-1 (CUP-1), is involved in dietary cholesterol uptake in C. elegans (CUP-1). (Mus musculus) PubMed

 10293.

Hsc70 system of C. elegans (CeHsc70) is characterized by a high ATP turnover rate and limited by post-hydrolysis nucleotide exchange. (Mus musculus) PubMed

 10294.

structure of the FH-binding protein, FhbB, was solved to 1.7 A resolution; study provides significant new insight into the molecular basis of FH/FhbB interaction and advances our understanding of the role that T. denticola plays in the development and progression of periodontal disease.[FHBB] (Mus musculus) PubMed

 10295.

new insight into interaction between pb5 and FhuA [FhuA] (Mus musculus) PubMed

 10296.

Identification of 68 RpoN-binding sites and 82 operons positively controlled by RpoN, among which 37 operons had ChIP-identified binding sites (RpoN). (Mus musculus) PubMed

 10297.

ISP1 has a primary role in flagellar homeostasis, disruption of which affects differentiation and flagellar pocket dynamics. [ISP1] (Mus musculus) PubMed

 10298.

The results demonstrate that multicopper oxidase -3(MCO3) can be classified as a laccase and suggest that MCO3 has a somewhat broader substrate specificity than MCO2 orthologs (MCO3). (Mus musculus) PubMed

 10299.

new insight into interaction between pb5 and FhuA [pb5] (Mus musculus) PubMed

 10300.

chloride-dependent alpha-amylases activity [alpha-amylase] (Mus musculus) PubMed

 10301.

A novel cysteine protease receptor, CPBF1, is involved in the trafficking and processing of EhCP-A5. [EhCP-A5] (Mus musculus) PubMed

 10302.

The study revealed that two regulatory regions co-operate to repress PAD1 expression, this being alleviated on exposure to stumpy induction factor in pleomorphs or cAMP analogues that act as stumpy induction factor mimics in monomorphs (PAD1). (Mus musculus) PubMed

 10303.

study demonstrates aspartate 1-decarboxylase (ADC)has both ADC and cysteine sulfinic acid decarboxylase(CSADC)activity; findings suggest residue Q377, localized at the active site of AeADC, could better interact with aspartate through hydrogen bonding, which may play a role in aspartate selectivity [aspartate 1-decarboxylase] (Mus musculus) PubMed

 10304.

this experiment demonstrated that FecA1 is an important determinant of the host-colonization ability and Mtz resistance of H. pylori through Fe(2+) supply to SodB, suggesting that FecA1 may be a possible target for the development of a novel bactericidal drug. (Mus musculus) PubMed

 10305.

forms polarized epithelium essential for multicellular development;identified alpha-catenin ortholog that binds beta-catenin-related protein; both essential for epithelium formation, polarized protein secretion, multicellular morphogenesis [alpha-ctenin; beta-catenin] (Mus musculus) PubMed

 10306.

This study focused on identifying the transcriptional and cell-signaling responses activated in A549 alveolar carcinoma cells incubated in the presence of A. fumigatus wild-type and DeltaPrtT protease-deficient germinating conidia and culture filtrates.[PrtT] (Mus musculus) PubMed

 10307.

These data indicate that the rapid increase in circulating activin A during LPS-induced inflammation is regulated at the posttranscriptional level.[activin A] (Mus musculus) PubMed

 10308.

ArsS, in addition to its role in urease gene transcription, is also involved in the recruitment of urease proteins to the inner membrane to augment acid acclimation during acute acid exposure.[ArsS] (Mus musculus) PubMed

 10309.

Three-dimensional structure and determinants of stability. [IscU] (Mus musculus) PubMed

 10310.

structure and catalytic mechanism of isocitrate dehydrogenase [isocitrate dehydrogenase] (Mus musculus) PubMed

 10311.

a series of X-ray structures of ATCase.nucleotide complexes [ATCase] (Mus musculus) PubMed

 10312.

Mfd remains bound to the DNA in a long-lived complex that could act as a marker for sites of DNA damage, directing assembly of subsequent DNA repair factors [mfd] (Mus musculus) PubMed

 10313.

x-ray crystallography of BetP and observation of four new conformations at once: an outward-open apo and an outward-occluded apo state, and two closed transition states--one in complex with betaine and one substrate-free [BetP] (Mus musculus) PubMed

 10314.

Data support a model whereby the eIF2beta-K-boxes and eIF4G-RS1 domain, along with the eIF5 C-terminal domain are involved in shifting the ribosome to a closed state after mRNA binding. [eIF2beta, eIF4G, eIF5] (Mus musculus) PubMed

 10315.

Mammalian and yeast methionine sulfoxide reductase MsrA reduced free methionine sulfoxide much more efficiently than methionine sulfoxide reductase MsrB. [MsrA, MsrB] (Mus musculus) PubMed

 10316.

Helicobacter pylori arginase modulates multiple host signaling and metabolic pathways of infected gastric epithelial cells.[RocF] (Mus musculus) PubMed

 10317.

analysis of the crystal structure of Kluyveromyces marxianus Hsv2, an Atg18 paralog, at 2.6 A resolution [Hsv2] (Mus musculus) PubMed

 10318.

These findings indicate that Staphylococcus aureus leukotoxins enhance the host inflammatory response and influence the outcome of infection.[LukGH] (Mus musculus) PubMed

 10319.

KREPB4 and KREPB5 form intermolecular heterodimers with the catalytically active editing endonucleases, which is unprecedented among known RNase III proteins.[KREPB4 protein, Trypanosoma brucei; KREPB5 protein, T. brucei] (Mus musculus) PubMed

 10320.

These findings suggest that Asp2 is a bifunctional protein that is essential for both GspB transport and correct glycosylation.[Asp2, GspB] (Mus musculus) PubMed

 10321.

Alkaline phosphatase ALP1 is a functional receptor that plays an important role in the toxicity of the Cry4Ba and Cry11Aa proteins. [ALP1] (Mus musculus) PubMed

 10322.

The P148L mutation specifically inhibits transport velocity and thereby blocks the lethal effect of elevated melibiose transport in the Gly117 mutants.[MelB] (Mus musculus) PubMed

 10323.

specificity-determining residues have diverged in the OSBS family [OSBS] (Mus musculus) PubMed

 10324.

ENV1 is a major determinant in regulation of sexual development. [Env1] (Mus musculus) PubMed

 10325.

Rca1 influences host sensing, hyphal development.[Rca1] (Mus musculus) PubMed

 10326.

The goal of this study was to elucidate the inheritance of resistance to Ug99 in Norin 40 and map the Sr gene(s).[Sr42] (Mus musculus) PubMed

 10327.

OsIAA13 is involved in auxin signaling and controls the expression of genes that are required for lateral root initiation in rice.[OsIAA13] (Mus musculus) PubMed

 10328.

Functional characterisation of Arl6 in the flagellated model eukaryote Trypanosoma brucei, is described.[ARL6] (Mus musculus) PubMed

 10329.

PP1 gamma is involved in proliferation and cell attachment to the host cell. [PP1 gamma] (Mus musculus) PubMed

 10330.

IGF-1 increases vascular smooth muscle cell proliferation by increasing PI3K activity and inhibiting PTEN activity. [PI3K; PTEN] (Mus musculus) PubMed

 10331.

a scheme of the sodium potential generation by Na(+)-NQR based on the redox- and sodium-dependent conformational changes in the enzyme [Na(+)-NQR] (Mus musculus) PubMed

 10332.

SspA and SspB are immunostimulatory components and play role in modulating the host's innate immunity.[SspA, SspB] (Mus musculus) PubMed

 10333.

These results suggest that specific DHNs contribute considerably to the high stress tolerance of mosses.[PpDHNA, PpDNHB] (Mus musculus) PubMed

 10334.

MoSwi6 functions in the MoMps1 pathway to govern growth, development and full pathogenicity.[Momps1, Moswi6] (Mus musculus) PubMed

 10335.

These observations reaffirm the necessity of the N-terminal lysine-rich residues of the Red clover necrotic mosaic virus capsid protein for efficient virion accumulation.[Capsid protein] (Mus musculus) PubMed

 10336.

TaWIR1 contributes to post-penetration resistance to Magnaporthe oryzae, but not Blumeria graminis f. sp. tritici, in wheat.[TaWIR1] (Mus musculus) PubMed

 10337.

role of DGAT2 ub triacylglycerol biosynthesis [DGAT2] (Mus musculus) PubMed

 10338.

Cytokinin, which is essential for nodule organ formation, regulates MtCLE13 expression. Simultaneous knockdown of MtCLE12 and MtCLE13 resulted in increased nodule number, implying that both genes play a role in controlling nodule number. [CLE12, CLE13] (Mus musculus) PubMed

 10339.

the 3.5 A crystal structure of the transporter-binding protein complex BtuCD-BtuF (BtuCD-F) trapped in an beta-gamma-imidoadenosine 5'-phosphate (AMP-PNP)-bound intermediate state [BtuC, BtuD, BtuF] (Mus musculus) PubMed

 10340.

three related crystal structures of XylE, an Escherichia coli homologue of GLUT1-4, in complex with D-xylose, D-glucose and 6-bromo-6-deoxy-D-glucose, at resolutions of 2.8, 2.9 and 2.6 A, respectively (Mus musculus) PubMed

 10341.

The assembly of the bacterial cell division FtsZ protein in the presence of constantly replenished GTP was studied as a function of Mg(2+) concentration (at neutral pH and 0.5 M potassium).[FtsZ] (Mus musculus) PubMed

 10342.

Cdc28 phosphorylates Gin4 and activates its kinase activity, which in turn phosphorylates the Sep7. [Cdc28, Gin4, Sep7] (Mus musculus) PubMed

 10343.

Determined is the three-dimensional (3D) solution structure of Calmodulin-like protein, EhCaM, using NMR. [EhCaM] (Mus musculus) PubMed

 10344.

This study showed that the involvement of NlpI in two key pathogenesis processes of meningitis may make this bacterial factor a potential target for prevention and therapy of E. coli meningitis [NlpI] (Mus musculus) PubMed

 10345.

The demonstration of Prc in the evasion of classical complement-mediated serum killing of pathogenic E. coli makes this factor a potential target for the development of therapeutic and preventive measures against E. coli bacteremia.[Prc] (Mus musculus) PubMed

 10346.

No obvious differences in growth rates and sporulation of the strains were found after deletion of polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) biosynthetic gene clusters.[PKS;NRPS] (Mus musculus) PubMed

 10347.

Draft genome sequencing, mutagenesis, and heterologous biosynthesis provided the 57.6 kb merochlorin gene cluster that contains two genes encoding bacterial vanadium-dependent haloperoxidase (VHPO) genes. [vanadium-dependent haloperoxidase] (Mus musculus) PubMed

 10348.

Two chitin synthase genes, AgCHS1 and AgCHS2, were expressed in egg, larval, pupal and adult stages but AgCHS2 was expressed at low levels. AgCHS1 was expressed in the carcass. AgCHS2 was expressed in the foregut. [AgCHS1; AgCHS2] (Mus musculus) PubMed

 10349.

Hematopoietic cells originally express higher levels MCM 2 protein and undergo more frequent apoptosis following doxorubicin-induced DNA-damage in the presence of the FLV envelope protein gp70.[gp70] (Mus musculus) PubMed

 10350.

OsRab7B3 act as a stress-inducible gene that plays an important role in the leaf senescence process. (Mus musculus) PubMed

 10351.

Synergism of the two Myb domains of Tay1 protein results in high affinity binding to telomeres [Tay1] (Mus musculus) PubMed

 10352.

DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice [DLT] [GSK2] (Mus musculus) PubMed

 10353.

Data indicate that small heat shock protein Hsp21 is crucial for multiple stages of pathogenicity: [Hsp21] (Mus musculus) PubMed

 10354.

BmVMP90 is an ovarian protein, expressed at the end of vitellogenesis. Gene knockdown compromises follicle integrity but does not disrupt choriogenesis. [VMP90] (Mus musculus) PubMed

 10355.

The role of Salmonella pathogenicity island 2 (SPI-2) and spvB and sifA, both SPI-2 effectors, in Salmonella colitis and diarrhea in genetically resistant mice are reported.[SPI-2; spvB; sifA] (Mus musculus) PubMed

 10356.

The structurally conserved Plk4 protein, SmSak, was largely expressed in schistosome female ovary and vitellarium.[SmSak] (Mus musculus) PubMed

 10357.

Synergism of the two Myb domains of Tay1 protein results in high affinity binding to telomeres [Tay1] (Mus musculus) PubMed

 10358.

Under low oxygen conditions, the sac6 deletion mutant grew poorly. [Sac6] (Mus musculus) PubMed

 10359.

The Tlo proteins are structurally anchored to Mediator complex through Med3. [Med3] (Mus musculus) PubMed

 10360.

CfcI displays optimal activity at pH 4 and 55-65 degrees C and releases monomers during chitin hydrolysis. [CfcI] (Mus musculus) PubMed

 10361.

CrDelta4FAD has an N-terminal cytochrome b(5) domain, distinguishing it from other known plastid desaturases. [CrDelta4FAD] (Mus musculus) PubMed

 10362.

Adrenomedullin is overproduced in airway epithelial cells and smooth muscle cells in the trachea of asthmatic guinea pigs. (Mus musculus) PubMed

 10363.

fimH gene plays a role in adherence of pathogenic E. coli to canine endometrium.[fimh] (Mus musculus) PubMed

 10364.

The study describes an equilibrium model of capsid protein polymerization for the kinetic analysis of in vitro assembly of capsid protein into polymer tubes. [capsid protein] (Mus musculus) PubMed

 10365.

These results indicate that OsGA20ox1 is a strong candidate gene for major QTL controlling seedling vigor in rice.[OsGA20ox1] (Mus musculus) PubMed

 10366.

Bcr1 and Hwp1 are required for oral Candidiasis infection. [Bcr1] (Mus musculus) PubMed

 10367.

BcAtf1 controls a diversity of cellular processes and has broad regulatory functions.[BcAtf1] (Mus musculus) PubMed

 10368.

The cut-off point of the expression level of Pfg377 ortholog gene could be used to predict the infectiousness of P. vivax (Mus musculus) PubMed

 10369.

opgB and opgC mutations had no significant impact on mice virulence as well as on competitive organ colonization. In low osmotic conditions, opgB and opgC mutants exhibited delay in growth initiation in the presence of sodium deoxycholate. [opgB] (Mus musculus) PubMed

 10370.

These findings support previous data from pigs concerning the occurrence of widespread activation of PCT extrathyroidal gene expression during endotoxic shock in pigs [PCT] (Mus musculus) PubMed

 10371.

In sheep small intestine, dexamethasone caused a slight increment in erythromycin N-demethylase activity in the jejunal mucosa and a significant enhancement of cytochrome P 450 3A apoprotein level in the duodenal mucosa.[CYP3A] (Mus musculus) PubMed

 10372.

Anisin1 plays an important role in the asexual development of A. nidulans by supporting conidiation, especially at elevated cultivation temperatures. Anisin1 may be involved in sensing/signaling elevated H2O2 levels. [Anisin1] (Mus musculus) PubMed

 10373.

XIAO is a regulator of brassinosteroids signaling and cell division. Thus, XIAO may provide a possible connection between brassinosteroids and cell-cycle regulation in controlling organ growth. [XIAO] (Mus musculus) PubMed

 10374.

LuxT was identified and characterized to be involved in the quorum sensing system and in regulating extracellular protease production and motility. [LuxT] (Mus musculus) PubMed

 10375.

X-ray structure of the GcpE-MEcPP complex (GcpE) (Mus musculus) PubMed

 10376.

Flagellar regulator FlhF is regulated by a quorum sensing master regulator SmcR. [SmcR] (Mus musculus) PubMed

 10377.

amino acid transporters as regulators of FLO11 and invasive growth [FLO11] (Mus musculus) PubMed

 10378.

Overexpression of NRPS4 leads to increased surface hydrophobicity. [NRPS4] (Mus musculus) PubMed

 10379.

IMC1h is involved in maintaining the cellular architecture which supports normal motility behaviour [IMC1h] (Mus musculus) PubMed

 10380.

TGF-beta regulates the balance of proliferation versus differentiation in the C. elegans germline in response to sensory cues that report population density and food abundance. [TGF-beta] (Mus musculus) PubMed

 10381.

Diseased lungs showed a significantly higher activity and expression of 5-LOX and COX-2 in a wide range of cell types, thus suggesting the likely involvement of both enzymes in the pathogenesis of bacterial porcine pneumonia [5-LOX; COX-2] (Mus musculus) PubMed

 10382.

The interaction of Spd1 with the polymerase processivity factor proliferating cell nuclear antigen (PCNA), complexed onto DNA.[PCNA] (Mus musculus) PubMed

 10383.

Determined is the crystal structure of the holoenzyme from Escherichia coli at 2.30 A in which the bicarbonate cofactor is bound to the enzyme active site. [MenB] (Mus musculus) PubMed

 10384.

XopB and XopS contribute to disease symptoms and bacterial growth, and suppress pathogen-associated molecular pattern (PAMP)-triggered plant defense gene expression.[XopS] (Mus musculus) PubMed

 10385.

Although impossible to prove a negative result, proper controls used in these studies suggested that the pog (predicted overlapping gene) ORF is not translated into a functional protein in SINV-1. [pog] (Mus musculus) PubMed

 10386.

TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity [RIGI] (Mus musculus) PubMed

 10387.

Endo III, a ubiquitous base excision repair enzyme, facilitates CTX phage-integration in vivo [Endo III] (Mus musculus) PubMed

 10388.

HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2. [p17] (Mus musculus) PubMed

 10389.

The N-terminal amino acid sequence in CiNTH is critical for DNA glycosylase activity. [CiNTH] (Mus musculus) PubMed

 10390.

Through map-based approach, we finally located the Lta1 gene to a region of 40.3 kb on the short arm of chromosome 11. There are 8 predicted open reading frames (ORFs) in this region and two of them were deleted in lta1 genome compared with the WT genome. [Lta1) (Mus musculus) PubMed

 10391.

BcRcn1 acts as a positive modulator of BcCnA and the Ca(2+)/calcineurin-mediated signal transduction in B. cinerea [BcRcn1] (Mus musculus) PubMed

 10392.

INVS/NPHP2 is conserved in C. elegans and that nphp-2 plays an important role in C. elegans cilia.[NPHP-2] (Mus musculus) PubMed

 10393.

In the rice zip4 mutant, the chiasma frequency is greatly reduced, although synapsis proceeds with only mild defects.[ZIP4] (Mus musculus) PubMed

 10394.

Plus-end-directed Kin3, a kinesin-3 type motor, mediates anterograde transport of ribonucleoprotein complexes (mRNPs) and split dynein Dyn1-Dyn2 functions in retrograde movement of mRNPs.[Kinesin-3, Dyn1, Dyn2] (Mus musculus) PubMed

 10395.

GehC(WM) is a major extracellular lipase of S. warneri M. [GehC] (Mus musculus) PubMed

 10396.

FlbD regulates both asexual and sexual differentiation (FlbD). (Mus musculus) PubMed

 10397.

OsCMO is transcriptionally induced in response to salt stress and functions in increasing glycinebetaine accumulation and enhancing tolerance to salt stress.[CMO] (Mus musculus) PubMed

 10398.

lga2-triggered mitophagy strongly depends on the mitochondrial fission factor Dnm1 (lga2, Dnm1). (Mus musculus) PubMed

 10399.

Results indicate that G. zeae carnitine acetyltransferase 1 (CAT1) and two (CAT2) are responsible for facilitating the exchange of acetyl-CoA across intracellular membranes, particularly between the mitochondria and the cytosol, during various developmental stages (CAT1 and CAT2). (Mus musculus) PubMed

 10400.

EhFdp1, a detoxifying oxygen reductase, is abundantly expressed in the cytoplasm of E. histolytica and that the protein levels are markedly increased upon oxygen exposure (EhFdp1). (Mus musculus) PubMed

 10401.

Mutations in the basic loop of UaY transcriptional activator suppress mutations in the dimerisation domain. [UaY] (Mus musculus) PubMed

 10402.

Overall, the results are consistent with a model in which the high-affinity RNA binding and RNA-annealing activities of the G-rich domain of TbRGG2 are essential for RNA editing in vivo (TbRGG2). (Mus musculus) PubMed

 10403.

Structural dynamics of the NTNHA molecule revealed by SAXS may explain its binding to BoNT to form the BoNT/NTNHA complex. [NTNHA] (Mus musculus) PubMed

 10404.

The present results do not exclude the possibility that SLa takes part in lipid metabolism or other physiological processes. However, skin-color regulation is the only definite role of SLa so far demonstrated in this species.[somatolactin alpha] (Mus musculus) PubMed

 10405.

Study identified a CCR7 orthologue in rainbow trout; data suggest that CCR7 plays an important role in lymphocyte trafficking during rainbow trout infections, in which CCR7 appears to be implicated in the recruitment of B lymphocytes into the gut. (Mus musculus) PubMed

 10406.

NsdC is required for production of asexual sclerotia, normal aflatoxin biosynthesis, and conidiophore development (NsdC). (Mus musculus) PubMed

 10407.

Distinct host protein interaction profiles of p30 and p28 could, in part, be responsible for differences in HTLV-1 and HTLV-2 pathobiology.[p30] (Mus musculus) PubMed

 10408.

Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover [RpfR] (Mus musculus) PubMed

 10409.

biochemical characterization of P-gp from Caenorhabditis elegans and its crystal structure at a resolution of 3.4 angstroms [p-glycoprotein] (Mus musculus) PubMed

 10410.

miR-26b promotes granulosa cell apoptosis by targeting ATM during follicular atresia in porcine ovary [miR-26b] (Mus musculus) PubMed

 10411.

The oxidation of d-glucose by quinoprotein glucose dehydrogenase initiates a reduction in pH that inhibits prodigiosin production through transcriptional control of the prodigiosin biosynthetic operon.[quinoprotein glucose dehydrogenase] (Mus musculus) PubMed

 10412.

A structural study reveals that the VcHfq protein does not change shape on complex formation but the RNA does, suggesting that a chaperone role for VcHfq is a critical part of the VcHfq-Qrr interaction (Hfq). (Mus musculus) PubMed

 10413.

The CopRS two-component system (also known as Hik31-Rre34) is essential for copper resistance in Synechocystis sp. PCC 6803.[CopS] (Mus musculus) PubMed

 10414.

The data suggest that only mprF2 is involved in the aminoacylation of phosphatidylglycerols in enterococci, while mprF1 does not seem to have a role in aminoacylation (mprF1 and mprF2). (Mus musculus) PubMed

 10415.

The catalytic efficiencies of both cellobiose dehydrogenases for carbohydrates are rather similar, but CDH IIA exhibits 4- to 5-times-higher apparent catalytic constants than CDH IIB for most tested carbohydrates.[CDH IIA, CDH IIB] (Mus musculus) PubMed

 10416.

Authors conclude that the expression driven by the tetA promoter is controlled by a sequential mechanism that is robust, whereas sensitive to external signals (tetA). (Mus musculus) PubMed

 10417.

SRL1 regulates leaf rolling through inhibiting the formation of bulliform cells.[SRL1] (Mus musculus) PubMed

 10418.

analysis of molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex [ELY5, Nup37] (Mus musculus) PubMed

 10419.

The phenotype observed after RNAi against each of the PEX13s thus suggests that both PEX13 isoforms in trypanosomes have a dual function: they are essential components of the glycosomal matrix-protein import machinery and they also serve to ascertain the correct association of PEX14 with the glycosomal membrane.[PEX13] (Mus musculus) PubMed

 10420.

The authors demonstrated that MhbT is a specific 3-hydroxybenzoate transporter.[MhbT] (Mus musculus) PubMed

 10421.

Absence of sefD, either through mutation or by suppression of transcription at the body temperature of the host, may contribute to the virulence of Salmonella enterica by facilitating growth on a wide range of metabolites.[SefD] (Mus musculus) PubMed

 10422.

Results revealed the significant importance of a stretch of amino acid residues within the loop 8-loop 9 regions (E373-D434) responsible for the acid sensitivity of VaNhaB, a NhaB-type Na(+)/H(+) antiporter. [VaNhaB] (Mus musculus) PubMed

 10423.

It is proposed that the binding of RolR to its operator rolO blocks the transcription of rolHMD and of its own gene, thus negatively regulated resorcinol degradation in Corynebacterium glutamicum.[RolR, RolO] (Mus musculus) PubMed

 10424.

The extent of and basis for functional specialisation of the Rom2 and Tus1 GTP exchange factors that activate the yeast Rho1 GTPase, were examined.[RHO1, TUS1, ROM2] (Mus musculus) PubMed

 10425.

OsMGT1 is a transporter for magensium uptake in the roots and up-regulation of this gene is required for conferring aluminum tolerance in rice.[OsMGT1] (Mus musculus) PubMed

 10426.

Ssp1 phosphorylates and activates the catalytic subunit of AMPK (Ssp2) in its activation loop (Thr189) when cells are starved for nitrogen or glucose.[Ssp1, Ssp2] (Mus musculus) PubMed

 10427.

Chlapsin showed restricted enzymatic specificity and proteolytic activity influenced by redox agents and nucleotides, differentiating it from typical plant aspartic proteinases with a more specialized/regulated function for this Chlamydomonas enzyme. (Mus musculus) PubMed

 10428.

Hypercapnia increased expression of TNFa and decreased expression of NFKB in acute lung injury models. (Mus musculus) PubMed

 10429.

a protein complex consisting Ebp2, Rrs1 and Mps3 is involved in a wide range of activities at the nuclear envelope [Ebp2][Rrs1][Mps3] (Mus musculus) PubMed

 10430.

target loci of two inner nuclear membrane proteins, Ima1 and Man1 (Mus musculus) PubMed

 10431.

Distinct host protein interaction profiles of p30 and p28 could, in part, be responsible for differences in HTLV-1 and HTLV-2 pathobiology.[p28] (Mus musculus) PubMed

 10432.

OsPT1 is a key member of the Pht1 family involved in Pi uptake and translocation in rice under phosphate-replete conditions.[OsPht1;1] (Mus musculus) PubMed

 10433.

The expression of mu-Leg1, which shares 31% similarity with zb-Leg1 of zebrafish, was enriched in the small intestine (mu-leg1). (Mus musculus) PubMed

 10434.

HubP anchors three ParA-like ATPases to the cell poles and, through them, controls polar localization of the chromosome origin, the chemotactic machinery, and the flagellum [HubP (hub of the pole)] (Mus musculus) PubMed

 10435.

Plasma PfHRP2 has prognostic significance in African children with severe falciparum malaria.[PfHRP2] (Mus musculus) PubMed

 10436.

Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance [MgrA] (Mus musculus) PubMed

 10437.

Study identified and cloned the zebrafish orthologues of CCL21 and CCL25; expression of CCL25 was only detected in the thymus primordia in embryos. In adult fish, transcripts of CCL25 were maintained in the thymus, and they were also found in the brain and oocytes. [CCL25] (Mus musculus) PubMed

 10438.

A nucleoplasmic component of the meiotic machinery, HAL-2 (homolog alignment-2), provides a distinct contribution to the coordination of homolog pairing and synapsis. (Mus musculus) PubMed

 10439.

Bacterial polarization machinery is regulated by a eukaryotic-type Ser/Thr protein kinase, AfsK, which localizes to hyphal tips and phosphorylates DivIVA (AfsK). (Mus musculus) PubMed

 10440.

analysis of protonation state of E71 in KcsA and its role for channel collapse and inactivation [KcsA] (Mus musculus) PubMed

 10441.

Simian foamy virus integrase is required for Pol encapsidation and that the viral protease activity is integrase independent.[integrase;protease] (Mus musculus) PubMed

 10442.

The study found a functionally critical region outside the transmembrane domain core that is required for maximal protease activity.[GlpG rhomboid protein] (Mus musculus) PubMed

 10443.

MA16 protein in Zea mays is stably linked to a ribonucleotide(s). [MA16 protein] (Mus musculus) PubMed

 10444.

The normal functions of allantoicase include retarding cell division until a specific cell size is reached and coordinating the progression of development.[Allantoicase] (Mus musculus) PubMed

 10445.

Accumulation of PsbS and the resultant qE exerts control over photosynthesis in fluctuating light. Optimization of photoprotective processes is necessary for maximum photosynthetic productivity in the absence of photoinhibitory stress. [PsbS] (Mus musculus) PubMed

 10446.

HSP104 gene structure and expression in Trypanosoma cruzi, was characterized.[HSP104] (Mus musculus) PubMed

 10447.

RBP42 plays a critical role in modulating T. brucei energy metabolism.[RBP42] (Mus musculus) PubMed

 10448.

The general protein composition in Yap1p-overexpressing S. cerevisiae was investigated using proteomic techniques, and the changes in the expression of the potential Yap1p-targeted proteins, were quantified.[Yap1] (Mus musculus) PubMed

 10449.

The results demonstrated that Ghd7 plays an important role in controlling the flag leaf area in rice (Ghd7). (Mus musculus) PubMed

 10450.

Protein phosphatase Z modulates oxidative stress response. [PPZ] (Mus musculus) PubMed

 10451.

Opposing influences by subsite -1 and subsite +1 residues on relative xylopyranosidase/arabinofuranosidase activities of bifunctional beta-D-xylosidase/alpha-L-arabinofuranosidase. (Mus musculus) PubMed

 10452.

These results suggest that fugu IL-6 regulates antibody production through STAT3 signaling via IL-6R and gp130.[IL-6R, gp130,STAT3] (Mus musculus) PubMed

 10453.

OsRDR6 played a key role in small RNA biogenesis and directly illustrates the crucial functions of tasiR-ARFs in rice development. [OsRDR6] (Mus musculus) PubMed

 10454.

PVE1 functions downstream of RGD2 in a pathway that intersects and interacts with the trans-acting small interfering RNA pathway.[PVE1] (Mus musculus) PubMed

 10455.

The isolation of a brittle culm mutant, bc15, and the map-based cloning of the BC15/OsCTL1 (for chitinase-like1) gene affected in the mutant, is reported.[BC15] (Mus musculus) PubMed

 10456.

transcriptional reprogramming by AM fungal LCOs strictly depends on MtNFP and largely requires MtDMI3.[MtNFP, MtDM13] (Mus musculus) PubMed

 10457.

Enterococcus faecalis SufU scaffold protein enhances SufS desulfurase activity by acquiring sulfur from its cysteine-153. (Mus musculus) PubMed

 10458.

crystals of polynucleotide phosphorylase belonged to the monoclinic space group C2, with unit-cell parameters a = 132.76, b = 128.38, c = 133.01 A, gamma = 93.3 degrees , and diffracted to a resolution of 2.00 A[polynucleotide phosphorylase ] (Mus musculus) PubMed

 10459.

Under physiological conditions, the KcsA outer vestibule undergoes relatively large dynamic rearrangements upon inactivation. [KcsA] (Mus musculus) PubMed

 10460.

A novel core protein CP55 of the Dictyostelium centrosome is required for integrity and stability of the corona, centrosome duplication, maintenance of ploidy, and growth on bacterial substrate.(CP55 protein) (Mus musculus) PubMed

 10461.

These data suggested that OsTLP27 encodes a protein with a novel function in photosynthesis and chloroplast development in rice. [TLP27] (Mus musculus) PubMed

 10462.

Rht-D1b (plant height reduced gene) represents a conserved genomic region as implied by high gene sequence identity, maintenance of gene colinearity, and the presence of multiple conserved noncoding sequences that are shared by other grasses. [Rht-D1b] (Mus musculus) PubMed

 10463.

Staphopain A is an important immunomodulatory protein that blocks neutrophil recruitment by specific cleavage of the N-terminal domain of human CXCR2 [Staphylococcus aureus] (Mus musculus) PubMed

 10464.

These data provide evidence that the secretion of leptin, ghrelin, and orexin are seasonally dependent, with relationships that are subject to photoperiodic regulation, and that leptin is an important factor that regulates ghrelin and orexin.[orexin] (Mus musculus) PubMed

 10465.

The authors identified a cell surface protease that is involved in the processing of 21-residue competence-stimulating peptide (CSP) to generate the 18-residue CSP.[SepM] (Mus musculus) PubMed

 10466.

All of the UpaH variants examined retained a conserved ability to mediate binding to extracellular matrix (ECM) proteins.[UpaH] (Mus musculus) PubMed

 10467.

(protein kinase C Apl III; protein kinase Mzeta; PKMzeta) Serotonin induces cleavage of PKC Apl III in motor neuron processes in a calpain- and protein synthesis-dependent manner but does not induce cleavage of PKC Apl III in sensory neuron processes. (Mus musculus) PubMed

 10468.

CDPK1 is essential for the transmission of P. berghei to the mosquito and for multiple aspects of sexual development, including egress of male gametes from activated gametocytes, and for differentiation of the zygote into an ookinete. [CDPK1] (Mus musculus) PubMed

 10469.

Both chemically-driven inflammation and axotomy caused an increase in the number of cocaine- and amphetamine-regulated transcript peptide-like (CART-L) immunoreactive nerve fibers in the circular muscle as well as in the mucosal layer.[CART-L] (Mus musculus) PubMed

 10470.

Analysis of the electrostatic surface potentials of both tryparedoxin and tryparedoxin peroxidase unveils the structural elements at the basis of functionally relevant interaction between the two proteins.[ tryparedoxin and tryparedoxin peroxidase] (Mus musculus) PubMed

 10471.

E. coli wild-type SSB stimulates the DinG DNA helicase via specific protein-protein interaction.[ssb; DinG] (Mus musculus) PubMed

 10472.

proximal fibroblast growth factor (FGF2/FGFR1) signaling compartmentalized in the placental endothelial caveolae via the FGFR substrate 2alpha that mediates formation of a FRS2alpha-GRB2-GAB1 complex [FGFR1] (Mus musculus) PubMed

 10473.

our analysis of the regulation of OsDRM2 by miR820 sheds light on the action of transposon-derived small RNAs, not only as a defense mechanism for host genomes but also as a regulator of interactions between hosts and their parasitic elements. (Mus musculus) PubMed

 10474.

PLP plays a crucial role in the determination of pulvinus development.[PLP] (Mus musculus) PubMed

 10475.

Triticum mosaic poacevirus enlists P1 rather than HC-Pro to suppress RNA silencing-mediated host defense. (Mus musculus) PubMed

 10476.

Antigenic region located between amino acids (aa) 55 to 110 on the E(rns) protein of CSFV Alfort/187, and two amino acids at position 102 and 107 are crucial for the interaction with antibodies. (Mus musculus) PubMed

 10477.

IL1B regulates expression of IL1R1 and IL1RAP and stimulates expression of PTGS1 and PTGS2 for endometrial synthesis of prostaglandins during the peri-implantation period of pregnancy in pigs. [IL1R1] (Mus musculus) PubMed

 10478.

The results indicated that MSI3 was essential for cell growth.[MSI3] (Mus musculus) PubMed

 10479.

LTP5 (lipid transfer protein 5) is involved in defense response to certain pathogens.[LTP5] (Mus musculus) PubMed

 10480.

The results suggest that OsSPX-MFS1 is a key player in maintaining phosphate (Pi) homeostasis in the leaves, potentially acting as a Pi transporter.[MFS1] (Mus musculus) PubMed

 10481.

Ptger4b signaling is involved in follicle rupture during ovulation in the medaka ovary. [Ptger4b] (Mus musculus) PubMed

 10482.

The deconjugation of Atg8-phosphatidylethanolamine by the cysteine protease Atg4 plays dual roles in the formation of autophagosomes.[Atg4, Atg8] (Mus musculus) PubMed

 10483.

This study functionally characterizes two members of the rice (Oryza sativa) miR393 family and their target genes, OsTIR1 and OsAFB2.[miRNA 393, OsTIR1] (Mus musculus) PubMed

 10484.

The VP1 genes of the 9 strains shared 89.8%-99.7% similarity at the nucleotide level and 92.4%-99.6% at amino acid level with other DHAV-1 strains. [VP-1] (Mus musculus) PubMed

 10485.

A low concentration of Salicylic acid (SAL) increased S. aureus Eap expression possibly due to enhancement of sae (the two-component regulatory system saeRS). [Eap] (Mus musculus) PubMed

 10486.

These findings demonstrate the critical role of residue 193 in Erg3p function and azole resistance.[Erg3p] (Mus musculus) PubMed

 10487.

Sex in fugu is most likely determined by a combination of the two alleles of Amhr2. (Mus musculus) PubMed

 10488.

Iron stimulated vvpE transcription. [VvpE] (Mus musculus) PubMed

 10489.

Molecular dynamic (MD) simulations have been performed on Tth-MCO, a hyperthermophilic multicopper oxidase from thermus thermophilus HB27.[MCO] (Mus musculus) PubMed

 10490.

In R. sphaeroides, Irr diminishes the strong induction of genes for iron metabolism under iron starvation.[Irr] (Mus musculus) PubMed

 10491.

SIE3 (SymRK-interacting E3 ubiquitin ligase) is involved in rhizobial infection and nodulation in L. japonicus.[SIE3] (Mus musculus) PubMed

 10492.

BAF60a may also reside in the nucleolus. Here, we identify BAF60a homologue Snf12 as the fifth nucleolar protein in Dictyostelium.[BAF60a] (Mus musculus) PubMed

 10493.

Full length TSP-1 and the N-terminal domain of TSP-1 (NTSP) interact with T. cruzi surface calreticulin (TcCRT) and other surface proteins.[Calreticulin] (Mus musculus) PubMed

 10494.

[adipocyte soluble factor] Adipocytes of both rabbit and human secrete a soluble factor(s) that inhibits B-cell lymphopoiesis. (Mus musculus) PubMed

 10495.

These findings indicate that rat cytomegalovirus r129 is highly chemotactic, which has important implications during rat cytomegalovirus infection and reactivation and acceleration of transplant vascular sclerosis.[r129] (Mus musculus) PubMed

 10496.

The role of amino acids essential for function and specificty in a eukaryotic purine-cytosine NCS1 transporter, the FcyB protein of Aspergillus nidulans. (Mus musculus) PubMed

 10497.

Deletion of either Vpa1045 or Vpa1049 decreased translocation of Hcp2. [Hcp2] (Mus musculus) PubMed

 10498.

these data highlight the potential of MIP-1delta as a mediator of pathological bone resorption and provide insight into the molecular mechanism through which MIP-1delta enhances osteoclastogenesis. (Mus musculus) PubMed

 10499.

New macrolide, lincosamide, and streptogramin B resistance gene erm(43) was detected in two different DNA fragments, of 6,230 bp and 1,559 bp, that were each integrated in the chromosome.[erm(43)] (Mus musculus) PubMed

 10500.

A mutant virus (16-5A, in which residues 16-20 of nsp1beta were substituted with alanines) encoding mutant nsp1beta induced significantly higher amount of type I IFN transcripts in infected macrophages. (nsp1 protein) (Mus musculus) PubMed

 10501.

OsHKT2;4 is selective for K+ among monovalent cations. OsHKT2;4 does not display a voltage-gated conducting pathway permeable to Ca2+. [HKT2;4] (Mus musculus) PubMed

 10502.

these blood-stage 6-cys proteins operate as a pair and play redundant roles either in erythrocyte invasion or in host-immune interactions [P12][P41] (Mus musculus) PubMed

 10503.

Alginate lyase preferably degraded the alginate with glycosidic bond in M-G linkage. [alginate lyase] (Mus musculus) PubMed

 10504.

zRICH may facilitate axon regeneration by regulating the axonal cytoskeleton and facilitating the formation of new neurite branches.[rich protein] (Mus musculus) PubMed

 10505.

These data also suggest that integrin plays a major role in maintaining proper CKI-1/p27(KIP1) levels in the cell.[Pat-3] (Mus musculus) PubMed

 10506.

Deletion of an orphan C(5) -cytosine methyltransferase, hpyAVIBM in H. pylori strains AM5and SS1 has a significant effect on the expression of number of genes belonging to motility, adhesion and virulence.[hpyAVIBM] (Mus musculus) PubMed

 10507.

Site directed mutagenesis reveals critical amino acid positions in the DNA unwinding ability of the dnaA protein of Thermotoga maritima. [dnaA] (Mus musculus) PubMed

 10508.

The data identify WSC-1 and HAM-7 as the major cell wall sensors that regulate two distinct MAK-1-dependent cellular activities, cell wall integrity and hyphal anastomosis, respectively.[WSC-1, HAM-7, MAK-1] (Mus musculus) PubMed

 10509.

These findings demonstrate that VEGF-E, both directly and indirectly, regulates keratinocyte function, thereby promoting epidermal regeneration.[VEGF-E] (Mus musculus) PubMed

 10510.

Triticum aestivum ZYP1 has a putative DNA-binding S/TPXX motif in its C-terminal region and interacts non-preferentially with both single- and double-stranded DNA in vitro. (Mus musculus) PubMed

 10511.

Silencing of tacA via RNAi leads to developmental defects and dysregulation of developmentally regulated and Ca(2+)-regulated marker genes (tacA). (Mus musculus) PubMed

 10512.

A newly identified HKT isoform, No-OsHKT2;2/1 can contribute to Nona Bokra salt tolerance by enabling root K uptake under saline conditions (OsHKT2;2 and OsHKT2;1). (Mus musculus) PubMed

 10513.

analysis of the early temporal and spatial interaction of the Sindbis virus capsid and E2 proteins with reverse genetics [capsid, E2] (Mus musculus) PubMed

 10514.

The rtfA gene, encoding a RNA-pol II transcription elongation factor-like protein, similar to Saccharomyces cerevisiae Rtf1, is associated with secondary metabolism and morphological development in Aspergillus nidulans.[rtfA] (Mus musculus) PubMed

 10515.

Uridine phosphorylase conformer differs in sugar pucker and uracil orientation from the unbound conformer and the transition-state structure. [UP] (Mus musculus) PubMed

 10516.

Results show that the first 20 N-terminal amino acids of ARO are sufficient for rhoptry membrane targeting (ARO). (Mus musculus) PubMed

 10517.

Results show that the first 20 N-terminal amino acids of ARO are sufficient for rhoptry membrane targeting (ARO). (Mus musculus) PubMed

 10518.

The authors show that RHO2 does not regulate glucan synthase activity and the actin cytoskeleton, but physically interacts with PKC1 to regulate the cell wall integrity pathway.[RHO2] (Mus musculus) PubMed

 10519.

The study solved the crystal structure of the periplasmic domain of Vibrio parahaemolyticus CpxA (VpCpxA-peri) to a resolution of 2.1 A and investigated its interaction with CpxP. [CpxA] (Mus musculus) PubMed

 10520.

The essential nature of Cys-60 for oxidation is demonstrated by the C60S variant, which is not inhibited by peroxide in the presence or absence of substrate.[S-formylglutathione hydrolase] (Mus musculus) PubMed

 10521.

These results suggest a role of sheep TTF-1 in enhancing sheep reproduction performance and we propose it as a candidate gene for selection.[TTF-1] (Mus musculus) PubMed

 10522.

These results suggest an important novel function of U20 as a viral immune evasion protein during human herpesvirus 6B infection.[U20] (Mus musculus) PubMed

 10523.

Overall, these results indicate that protein kinase A influences secretion pathways directly related to virulence factor elaboration.[protein kinase A] (Mus musculus) PubMed

 10524.

Extended-spectrum beta-lactamase VEB-5 and 16S rRNA methyltransferase armA are located on one plasmid in Salmonella enterica from the United Kingdom. [VEB-5; armA] (Mus musculus) PubMed

 10525.

The Saccharomyces cerevisiae Hot1p regulated gene YHR087W (HGI1) has a role in translation upon high glucose concentration stress. [Yhr087wp] (Mus musculus) PubMed

 10526.

Nup53 has 2 membrane binding sites. The C-terminal domain has membrane-deforming capabilities, & is needed for de novo nuclear pore complex assembly & insertion into the interphase nuclear envelope. Nup53 dimerization is crucial for its function. (Mus musculus) PubMed

 10527.

This study suggests that at least two of the ncRNA species complex with HU protein and help the formation or maintenance of the architecture of the E. coli chromosome.[HU protein] (Mus musculus) PubMed

 10528.

It was proposed that SurA protects the PnlH signal sequence from the hydrophobic periplasm during targeting of PnlH to the outer membrane.[SurA] (Mus musculus) PubMed

 10529.

Data indicate that in serotype O9a, WbdA is a bifunctional alpha-(1-->2)-, alpha-(1-->3)-mannosyltransferase, and its counterpart in serotype O8 is trifunctional (alpha-(1-->2), alpha-(1-->3), and beta-(1-->2)): [WbdA] (Mus musculus) PubMed

 10530.

[TcpG; toxin-coregulated pilus G protein] Comprehensive redox characterization and high-resolution crystal structure of TcpG at 1.2 A, including refined hydrogen atoms, are reported. (Mus musculus) PubMed

 10531.

Out of 38 LysR-type transcriptional regulators, only one severely affected intestinal colonization in the suckling mouse model of cholera: the methionine metabolism regulator, MetR.[MetR] (Mus musculus) PubMed

 10532.

These results showed that HasB is a nonessential enzyme for capsule formation; HasB2, a novel UDP-glucose 6 dehydrogenase, was also identified.[HasB; HasB2] (Mus musculus) PubMed

 10533.

Data indicate that the multidomain protein Epf from S. pyogenes serotype M49 is a streptococcal adhesin, and epf-deficient mutant showed significantly decreased adhesion to and internalization into human keratinocytes [Epf] (Mus musculus) PubMed

 10534.

Peptidoglycan deacetylation by EF1843 is a component of the arsenal that enables E. faecalis to thrive inside mammalian hosts.[EF1843] (Mus musculus) PubMed

 10535.

Hac1, a well-characterized basic leucine zipper (bZIP) transcription factor involved in the unfolded protein response (UPR) was used as a model to investigate interactions between bZIP transcription factors and their target sites.[Hac1] (Mus musculus) PubMed

 10536.

This work describes a complete site-specific analysis of recombinant HIV gp140 with 27 potential glycosylation sites. [gp140] (Mus musculus) PubMed

 10537.

structural change of MA protein upon calmodulin bining [MA] (Mus musculus) PubMed

 10538.

The simultaneous presence of E138K and Y181C mutations in HIV-1 reverse transcriptase impaired each of enzyme activity, processivity, rate of processive DNA synthesis, and deoxynucleoside triphosphate (dNTP) affinity. [HIV1-RT] (Mus musculus) PubMed

 10539.

Interestingly, three mutant proteins (C179S, C186S and C581S) of the 130-kDa replication protein failed not only to be guanylylated, but also to bind to the replication template and membranes.[130-kDa replication protein] (Mus musculus) PubMed

 10540.

This study demonstrates that catalytically inactive Yen1 contributes to genome stability and that there is a negative genetic interaction between Yen1 and Sgs1 in K. lactis (Yen1). (Mus musculus) PubMed

 10541.

Based on the quantum mechanical and molecular mechanical molecular dynamic simulations and free energy profiles, a near attack conformer was obtained for the degradation of hyaluronan catalyzed by the hyaluronate lyase. [hyaluronate lyase] (Mus musculus) PubMed

 10542.

DOT1A over-expression causes continuous replication of the nuclear DNA, whereas depletion of DOT1A by RNAi abolishes replication (DOT1A). (Mus musculus) PubMed

 10543.

The data indicates that CAF-1b and ASF1A are important for the maintenance and inheritance of epigenetically determined states at silent telomeric variant surface glycoprotein expression sites in T. brucei (CAF-1b and ASF1A). (Mus musculus) PubMed

 10544.

Characterization of the recombinant AbfA and AbfB proteins revealed that both enzymes do not only hydrolyze p-nitrophenyl-alpha-L-arabinofuranoside but are also capable of hydrolyzing p-nitrophenyl-beta-D-galactofuranoside. [AbfA, AbfB] (Mus musculus) PubMed

 10545.

These results further suggest a definite role of OmpU and OmpT in providing the structural integrity of the Vibrio cholerae flagellum as part of the surrounding sheath.[OmpU and OmpT] (Mus musculus) PubMed

 10546.

This work establishes MbiA as a novel cell shape regulator that appears to function through regulating MreB.[MbiA, MreB] (Mus musculus) PubMed

 10547.

Article discusses the spatial and temporal regulation of cytoskeleton reorganization via the Rap1 signaling pathway during chemotaxis with a focus on recent advances in the study of chemotaxis using a simple eukaryotic model organism, Dictyostelium discoideum. [Rap1 Review]] (Mus musculus) PubMed

 10548.

An ADP-glucose pyrophosphorylase small unit 1 (OsAGPS1) SNP (A-G) was significantly associated with increased amylose content, while a 12-bp deletion of AGPase large unit 4 was significantly related to the decreased breakdown viscosity [AGPS1,AGPL4] (Mus musculus) PubMed

 10549.

The inhibition of phosphoinositide-specific phospholipase Cs activity resulted in severely retarded germination of basidiospores and oidia, reduced hyphal growth, and aberrant (branch-like structure) clamp cells.[PLC1, PLC2, PLC3] (Mus musculus) PubMed

 10550.

PYK2 responds to the fertilization-induced calcium transient by promoting reorganization of the cortical actin cytoskeleton to form the fertilization cone. [PYK2] (Mus musculus) PubMed

 10551.

3.2 A crystal structure of Vibrio cholerae INDY homologue [INDY] (Mus musculus) PubMed

 10552.

This study suggests that, following phosphate limitation, Streptomyces coelicolor PhoP functions as a 'master' regulator, suppressing central metabolism, secondary metabolism and developmental pathways until sufficient phosphate is salvaged to support further growth and, ultimately, morphological development (PhoP). (Mus musculus) PubMed

 10553.

Consequently, p27 of hepatitis delta virus activated the signal transducer and activator of transcription-3 (STAT-3) and the nuclear factor kappa B (NF-kappaB) via the oxidative stress pathway.[p27] (Mus musculus) PubMed

 10554.

This work demonstrated the importance of Dps for biofilm formation and poultry colonization, and the study also provides a basis for continued work using the Dps protein as a vaccine antigen when delivered through a Salmonella vaccine vector.[Dps] (Mus musculus) PubMed

 10555.

Deployment of YrSN104 singly or in combination to elite genotypes could play an effective role to lessen yield losses caused by stripe rust. (Mus musculus) PubMed

 10556.

microR164 is involved in the regulation of gene expression involved in the development and growth of grapes. (Mus musculus) PubMed

 10557.

These findings provided phenotypic evidence supporting roles for Spf1 in the maintenance of cellular calcium homeostasis, ER stress responses, hyphal development, biofilm formation and virulence in Candida albicans.[Spf1] (Mus musculus) PubMed

 10558.

The authors suggest that enteropathogenic Escherichia coli have evolved a mechanism to ready the cell for CesT protein expression in support of infection prior to Ler- and GrlA-related activities.[CesT] (Mus musculus) PubMed

 10559.

Resistance to artemether in vitro was significantly associated with a pfatp6 haplotype encoding two amino acid substitutions (pfatp6 A623E and S769N) (Mus musculus) PubMed

 10560.

glycoprotein 150 does not contribute to latency amplification. [gp150] (Mus musculus) PubMed

 10561.

XccR can bind HrpX, suggesting that these two regulatory proteins coactivate the virulence factor by binding to the different cis elements of the pip(Xcc) gene.[pip, XccR] (Mus musculus) PubMed

 10562.

The authors conclude that ExsE contributes to the negative regulation of type III secretion system 1 and, in addition, contributes to regulation of an adherence phenotype that is requisite for translocation of effector proteins into HeLa cells.[ExsE] (Mus musculus) PubMed

 10563.

The location of the predominant nucleotide-binding site of DnaG and induction of the stringent response in bacteria interferes with primer synthesis. (Mus musculus) PubMed

 10564.

Staphylococcus aureus isolates encode variant staphylococcal enterotoxin B proteins that are diverse in superantigenicity and lethality [SEB, strain MNBE and MNBD] (Mus musculus) PubMed

 10565.

Data indicate that the crystal structure of VanG D-alanine:D-alanine ligase (VanG) showed an unusual interaction between two dimers involving residues of the omega loop deeply anchored in the active site [VanG] (Mus musculus) PubMed

 10566.

It is likely that GntR1 represses gnd expression by preventing both RNA polymerase and RamA binding to the promoter.[GntR1, RamA] (Mus musculus) PubMed

 10567.

The gamma-butyrolactone receptor, ScbR, plays a key role in the S. coelicolor butanolide regulatory cascade and in determining the onset of the expression of the antibiotic regulatory genes.[ScbR] (Mus musculus) PubMed

 10568.

The authors show that both actinorhodin and its 3-ring biosynthetic intermediates [e.g., (S)-DNPA] can relieve repression of actAB by ActR in vivo.[actA, actB, actR] (Mus musculus) PubMed

 10569.

Crystal structure reveals the molecular mechanism that DndA employs to recognize its cofactor PLP, and suggests the potential binding site for the substrate L-cysteine on DndA (DndA). (Mus musculus) PubMed

 10570.

These results revealed the existence of a general mechanism for removal of Histone H3 lysine 4 trimethylation following gene repression.[Histone H3] (Mus musculus) PubMed

 10571.

LmjAQP1 is phosphorylated in vivo at Thr-197 and this phosphorylation requires LmjMPK2 activity.[AQP1, MPK2] (Mus musculus) PubMed

 10572.

The crystal structure of Leishmania major peroxidase in a complex with its substrate, L. major cytochrome c, was determined.[Peroxidase, cytochrome c] (Mus musculus) PubMed

 10573.

findings show the primary effects of the neuraminidase H275Y substitution on the pandemic H1N1 (H1N1pdm09) strain are to lengthen the mean eclipse phase of infected cells (from 6.6 to 9.1 h) and decrease (by 7-fold) the viral burst size [NA] (Mus musculus) PubMed

 10574.

studies suggest that the HPV16-E7 and Ad5-E1A viral oncoproteins bind to the same p300 CH1 domain to disrupt p300 function by distinct mechanisms[E1A oncoprotein] (Mus musculus) PubMed

 10575.

In summary, these data suggest a role for CTR4 in copper-related homeostasis and subsequently in fungal virulence.[CTR4] (Mus musculus) PubMed

 10576.

The Spo11 to catalyze meiotic DNA double-strand breaks(DSBs)at recombination hotspots(meiotic recombination protein SPO11). (Mus musculus) PubMed

 10577.

study obtained the room-temperature 2.1 angstrom resolution structure of the fully glycosylated precursor complex of cathepsin B [Cathepsin B] (Mus musculus) PubMed

 10578.

SPI38 is a novel protease inhibitor and is stable over a wide range of temperatures and pH values. [SPI138] (Mus musculus) PubMed

 10579.

result suggested that BmLASP1 may play an important role in the response of silkworm to BmCPV infection [LASP1] (Mus musculus) PubMed

 10580.

These results demonstrate that suhB(Bc) deletion compromises general protein secretion, including the activity of the type II and type VI secretion systems, and affects polymyxin B resistance, motility and biofilm formation.[SuhB] (Mus musculus) PubMed

 10581.

The signal peptidase ComC is indispensable for ComGC maturation and optimal cell surface exposure.[ComC] (Mus musculus) PubMed

 10582.

A functional and structural characterization of NirC from Salmonella typhimurium, is presented.[NirC] (Mus musculus) PubMed

 10583.

The TgIMP1 has multiple epitopes, with immunogenicity, suggesting that the TgIMP1 may be a vaccine candidate against toxoplasmosis.[IMP1] (Mus musculus) PubMed

 10584.

KstD(F) encodes a polypeptide consisting of 637 amino acid residues.[KstD(F)] (Mus musculus) PubMed

 10585.

low phytic acid1-7 (lpa1-7), a new ZmMRP4 mutation in maize(MRP4 ) (Mus musculus) PubMed

 10586.

Lack of KCS1 interferes with proper localization of the phagophore assembly site, leads to reduction of autophagosome formation, and causes the formation of autophagosome-like structure in abnormal subcellular locations.[KCS1] (Mus musculus) PubMed

 10587.

These results indicate that Stn, via regulation of OmpA membrane localization, functions in the maintenance of membrane composition and integrity.[Stn] (Mus musculus) PubMed

 10588.

Interactions With eEF1A1 contributes to endothelial nitric oxide synthase upregulation by monocyte locomotion inhibitory factor (monocyte locomotion inhibitory factor). (Mus musculus) PubMed

 10589.

Proper regulation of pfsr1 is required for parasite proliferation in human RBCs and over-expression of pfsr1 influences alternative splicing activity of P. falciparum genes in vivo (pfsr1). (Mus musculus) PubMed

 10590.

The crystal structure of Rpn12 defines a core structural motif for the PCI domain & potential protein-protein interaction sites. Mutation at 1 site impairs Rpn12 binding to Rpn10 in vitro & Rpn10 incorporation into proteasomes in vivo. Rpn12. (Mus musculus) PubMed

 10591.

30K proteins bound primarily to the ecdysone receptor-B1 and not to ultraspiracle (ecdysone receptor-B1). (Mus musculus) PubMed

 10592.

A gene, named furD, was identified by in silico approaches and we confirm here that it encodes a high-affin., high-capac. uracil transporter. We studied the expression of FurD and develop a kinetic model describing transporter-substrate interactions. (Mus musculus) PubMed

 10593.

UapC and AzgA are high-affinity, high-capacity, purine/H+ symporters, the first being specific for xanthine, uric acid and oxypurinol, whereas the second for adenine, hypoxanthine, guanine and purine. (Mus musculus) PubMed

 10594.

Loss of Ufm1 and consequently absence of Ufm1 conjugation with MTP resulted in diminished acetyl-CoA, the end-product of the beta-oxidation in the Ufm1(-/-) amastigote stage.[Ufm1] (Mus musculus) PubMed

 10595.

Pathogenicity assays showed that Stagonospora nodorum strains lacking Gba1 were essentially non-pathogenic whilst Gga1-impaired strains displayed significantly slower growth in planta.[Gba1, Gga1] (Mus musculus) PubMed

 10596.

[EAAT1; GLAST] A signaling cascade through EAAT-1/GLAST includes divalent calcium ion influx, activation of phosphatidylinositol 3-kinase and protein kinase B; and a detectable increase in mTOR phosphorylation. (Mus musculus) PubMed

 10597.

several mutations in the unrelated genes aceE and ribB rescue growth of DXS-defective mutants because the encoded enzymes allowed the production of sufficient DXP in vivo [aceE][ribB] (Mus musculus) PubMed

 10598.

Suggest hypothetical model of the post-translational events contributing to the wheat 7S globulin (glo-3/wheat storage protein/WP5212) profile in mature wheat kernels. (Mus musculus) PubMed

 10599.

the spatio-temporal transcriptional regulation of the OsHFP gene, which is proposed to be involved in anther programmed cell death, is reported. (Mus musculus) PubMed

 10600.

Otg2p and Otg3p are involved in alpha1,3-galactosylation of S. pombe oligosaccharides [Otg2p, Otg3p] (Mus musculus) PubMed

 10601.

In photoreceptor cells, RIBEYE and RIM2 are expressed along the synaptic ribbon. [RIM2] (Mus musculus) PubMed

 10602.

The results indicate that Pfnek-4 is not strictly gametocyte-specific, and is expressed in a small subset of asexual parasites displaying high rate conversion to sexual development.[nek-4] (Mus musculus) PubMed

 10603.

Wx(a) and ss3a synergistically increase the apparent amylose content in rice endosperm, and the possible reasons for this increase are discussed.[ss3a] (Mus musculus) PubMed

 10604.

data suggest that the bacterial effector VepA targets subunit c of V-ATPase and induces the rupture of host cell lysosomes and subsequent cell death. (Mus musculus) PubMed

 10605.

OsbZIP16 positively regulates drought resistance in rice. [OsbZIP16] (Mus musculus) PubMed

 10606.

Wx(a) and ss3a synergistically increase the apparent amylose content in rice endosperm, and the possible reasons for this increase are discussed.[Wx(a)] (Mus musculus) PubMed

 10607.

Protein interaction analyses reveal binding of EIIA(Ntr) to histidine kinase PhoR.[EIIA(Ntr)] (Mus musculus) PubMed

 10608.

These data indicate that Nsp2 is a multifunctional protein participating in the modulation of host inflammatory response, which suggests an important role of Nsp2 in pathogenesis and disease outcomes.[Nsp2] (Mus musculus) PubMed

 10609.

[connexin 11; cx-11] The requirement for cx-11 for anterior neural fate points to a crucial role for intercellular communication via gap junctions, probably through mediation of Ca2+ transients, in neural induction. (Mus musculus) PubMed

 10610.

VP19C as the first herpesviral capsid protein with nucleocytoplasmic shuttling property (Mus musculus) PubMed

 10611.

The structure of Hfq reveals a bipartite RNA-binding motif on the distal face that is composed of a purine nucleotide-specificity site and a non-discriminating linker site (Hfq). (Mus musculus) PubMed

 10612.

Chicken PD-1/PD-L1 pathway has immunoinhibitory functions, and PD-1 may be involved in Marek's disease pathogenesis, whereas PD-L1 could contribute to the establishment and maintenance of Marek's disease virus latency.[PD-1, PD-L1] (Mus musculus) PubMed

 10613.

These data strongly suggest that the Fur-like protein PerR directly regulates dpr and metQIN and plays a crucial role in oxidative stress response in Streptococcus suis.[PerR, metQIN] (Mus musculus) PubMed

 10614.

FasX base pairs to the extreme 5' end of mRNA from the pilus biosynthesis operon, and this RNA:RNA interaction reduces the stability of the mRNA.[FasX] (Mus musculus) PubMed

 10615.

SGT1 is induced by the potato virus X TGBp3 and enhances virus accumulation in Nicotiana benthamiana. [TGBp3] (Mus musculus) PubMed

 10616.

The C-terminal 37 amino acids (amino acids 87-123) containing a conserved C-terminal motif were found required for the self-interaction of TGB3.[TGB3] (Mus musculus) PubMed

 10617.

The genes cyaA and cyaC are solely responsible for increasing the levels of cAMP-CRP and code for the activity of DMSO reductase (DMSO is used as a terminal electron acceptor in this study) (DMSO reductase) (Mus musculus) PubMed

 10618.

MIL2 is responsible for the differentiation of primary parietal cells into secondary parietal cells in rice anthers.[MIL2] (Mus musculus) PubMed

 10619.

These findings demonstrate for the first time that Cryptococcus neoformans Plb1 aids fungal traversal across the blood-brain barrier by activating host cell Rac1 and its association with STAT3.[Plb1] (Mus musculus) PubMed

 10620.

TRAP removal from the sporozoite surface functions to break adhesive connections between the parasite and extracellular matrix or host cell receptors, which in turn is essential for motility and invasion. [TRAP] (Mus musculus) PubMed

 10621.

RNA-seq was used to identify a candidate for Bs4C, an R gene from pepper that mediates recognition of the Xanthomonas TALE protein AvrBs4.[AvrBs4] (Mus musculus) PubMed

 10622.

A conditional null mutant of PdxK was generated in Trypanosoma brucei bloodstream forms showing that this enzyme is essential for growth of the parasite in vitro and for infectivity in mice.[PdxK] (Mus musculus) PubMed

 10623.

The expression profile of Prx4 correlates well with protection from oxidative damage [Prx4]. (Mus musculus) PubMed

 10624.

The authors show that the proline codon-rich ORF mgtP mediates an increase in transcription of the mgtC and mgtB coding regions under conditions predicted to decrease the levels of proline-charged tRNA(Pro).[mgtP] (Mus musculus) PubMed

 10625.

Molecular modeling study suggesting that Dwarf14 interacts with and thereby may act as a receptor for strigolactone in plants. (Mus musculus) PubMed

 10626.

HtrA protease from Streptococcus pneumoniae digests both denatured proteins and the competence-stimulating peptide [HtrA, strains R895 or P1373] (Mus musculus) PubMed

 10627.

PmrAB is the global regulatory system that controls lipopolysaccharide modification [PmrA] (Mus musculus) PubMed

 10628.

mechanisms of PIP3 waves and PTEN dynamics in the emergence of cell polarity [PTEN] (Mus musculus) PubMed

 10629.

developmental regulator Opo enables polarized integrin localization by modulating Numb/Numbl, thus directing the basal constriction that shapes the vertebrate retina epithelium [numb/Numbl] (Mus musculus) PubMed

 10630.

The DNA sequence of Anman5a was 1825 bp in length, containing a 5'-flanking regulatory region, 2 introns and 3 exons when compared with the full-length cDNA.[Anman5A] (Mus musculus) PubMed

 10631.

The lack of par-5 in germ cells caused cell cycle deregulation, the accumulation of endogenous DNA damage and genomic instability.(14-3-3 gene par-5) (Mus musculus) PubMed

 10632.

These results suggest that Tyr-172 plays an important role in determining the large-ring cyclodextrin product profile of Corynebacterium glutamicum amylomaltase.[amylomaltase] (Mus musculus) PubMed

 10633.

Hsp90 expression is up-regulated in injured arteries and colocalizes with the apoptosis inhibitor, survivin, in vascular smooth muscle cell in vitro and in vivo.[Hsp90] (Mus musculus) PubMed

 10634.

VldW, an alpha-ketoglutarate/Fe(II)-dependent dioxygenase, regioselectively hydroxylates validamycin A to validamycin B.[VldW] (Mus musculus) PubMed

 10635.

Phosphorylation of purified Clb2 by Cdk1 is inhibited by catalytically active Mck1 but not catalytically inactive Mck1 in vitro.[CLB2] (Mus musculus) PubMed

 10636.

Expression of OsWRKY45, which encodes a transcription factor that plays a central role in defence mediated by salicylic acid, is induced by endoplasmic reticulum stress. [OsWRK45] (Mus musculus) PubMed

 10637.

The pH signaling pathway controls glycogen accumulation by regulating gsn expression.[GSN] (Mus musculus) PubMed

 10638.

Improper tagging resulted in the aggregation of VP26 in the nucleus, prevented efficient nuclear egress of viral capsids, and thus virion formation.[VP26] (Mus musculus) PubMed

 10639.

A cross-complementation assay was performed: substituting in the flagellar system of Salmonella one of these membrane proteins, FlhB, by the FlhB ortholog from Aquifex aeolicus.[FlhB] (Mus musculus) PubMed

 10640.

These findings revealed a fundamental role of CaMKII in the enteric nervous system.[CamKII] (Mus musculus) PubMed

 10641.

mir498 has a role in 1,25-Dihydroxyvitamin D3 suppression of telomerase expression and cancer growth (Mus musculus) PubMed

 10642.

These findings define Tet3 as a transcription regulator and reveal a molecular mechanism by which the 5mC hydroxylase and DNA binding activities of Tet3 cooperate to control target gene expression and embryonic development. [Tet3] (Mus musculus) PubMed

 10643.

We explored the frequency of sequence variation in hopZ during acute and chronic human infection and studied the association of hopZ with the phylogeographic population structure of H. pylori. [HopZ] (Mus musculus) PubMed

 10644.

the results are consistent with a more minor virulence role for the V. cholerae TRH (TDH-related hemolysins) in T3SS-positive strains compared to the functions attributed to the V. parahaemolyticus TDH and TRH proteins. [Trh] (Mus musculus) PubMed

 10645.

This study shows that tpxD encodes a functional thiol peroxidase involved in the adjustment of H(2)O(2) homeostasis in the cell. [TpxD] (Mus musculus) PubMed

 10646.

Hep1 acts as a specialized chaperone mediating the de novo folding of an Hsp70 chaperone [mtHSP70] (Mus musculus) PubMed

 10647.

The authors show that gp131 is located at the periphery of the baseplate and possibly associates with fibers that emanate from the baseplate.[gp131] (Mus musculus) PubMed

 10648.

The shoot jasmonic acid-isoleucine [JA-Ile] level of phyB mutants is higher than that of the wild-type strain MG20, suggesting that translocation of JA-Ile from shoot to root is impeded in the mutant.[phyB] (Mus musculus) PubMed

 10649.

Mutation in of the TOB1 gene results in pleiotropic phenotypes in the spikelet, such as abnormal morphology, formation of the two florets and premature termination of the meristem.[TOB1] (Mus musculus) PubMed

 10650.

OsMCA1 is involved in the regulation of plasma membrane Ca(2+) influx and NADPH oxidase-mediated generation of reactive oxygen species (ROS) induced by hypo-osmotic stress.[OsMCA1] (Mus musculus) PubMed

 10651.

OsNRAMP5 would also play a role in Fe and Mn transport during flowering and seed development.[OsNRAMP5] (Mus musculus) PubMed

 10652.

HO is required for biliverdin-induced lateral root formation in rice.[heme oxygenase] (Mus musculus) PubMed

 10653.

The isolation of full-length cDNAs of two isoforms of Ggamma [RGG1 and RGG2] from rice and their transcript regulation in response to abiotic stresses, are described.[RGG1, RGG2] (Mus musculus) PubMed

 10654.

Potential phosphorylation sites on the lipase by were identified by molecular modeling and ser/thr mapping and the activity of the lipase was shown to be decreased by CKI in a time-dependent manner.[CKI] (Mus musculus) PubMed

 10655.

The present study reports molecular characterization of small heat shock protein gene in Indian isolates of Chaetomium globosum. (Mus musculus) PubMed

 10656.

identification of the human immunodeficiency virus (HIV) co-receptor CCR5 as a cellular determinant required for cytotoxic targeting of subsets of myeloid cells and T lymphocytes by the S. aureus leukotoxin ED (LukED)[lukE; lukD] (Mus musculus) PubMed

 10657.

We report the role of QseE in S. Typhimurium pathogenesis as well as the interplay between these two histidine sensor kinases (QseC and QseE) in gene regulation. [QseC, QseE] (Mus musculus) PubMed

 10658.

We determined that a regulatory protein encoded by the STM4463 gene functions as an activator for STM4467 (arginine deiminase) expression which contributes to virulence. [STM4467, STM4463] (Mus musculus) PubMed

 10659.

There were no genetic polymorphisms of the sortase A gene associated with early childhood caries in two-year-old children [sortase A] (Mus musculus) PubMed

 10660.

Individual-specific receptor vCRL1 might be utilized to facilitate somatic self/nonself discrimination.[vCRL1] (Mus musculus) PubMed

 10661.

the overproduction of RAB16A protein in the transgenics enable them to display enhanced tolerance to salinity stress with improved physiological traits.[Rab16A] (Mus musculus) PubMed

 10662.

To determine the functions of RGB1, transgenic rice plants with suppressed expression of RGB1 were studied; these studies suggest that RGB1 has different functions than RGA1 [RGB1] (Mus musculus) PubMed

 10663.

LYP4 (lysin motif-containing protein 4) and LYP6 affect Rice susceptibility to both bacterial and fungal pathogens. [Lyp4; Lyp6] (Mus musculus) PubMed

 10664.

Two transcription factors, MYBS1 and MYBGA, present in rice (Oryza sativa) and barley (Hordeum vulgare), function to integrate diverse nutrient starvation and gibberellin (GA) signaling pathways during germination of cereal grains. [MYBS1 and MYBGA] (Mus musculus) PubMed

 10665.

The aCRY protein is a functionally important blue and red light-activated flavoprotein. [aCRY] (Mus musculus) PubMed

 10666.

hyperactive ATPase variants of the ParA homolog ParF display altered segrosome dynamics that block accurate DNA segregation[ParF] (Mus musculus) PubMed

 10667.

The gene vvsA was shown to constitute an operon with a downstream gene vvsB, and several Vibrio species were found to have orthologues of vvsAB.[vvsAB] (Mus musculus) PubMed

 10668.

The crystal structures of all three ferredoxin:NADP(+) reductase (FNRs) were solved, revealing major structural differences at the N-terminal domain and dimer interface. [FNR3] (Mus musculus) PubMed

 10669.

The result indicated that ENAC1 (a NAC transcritpion factor) was an early and transient regulator of stress responses in rice. [ENAC1] (Mus musculus) PubMed

 10670.

LpqW may directly activate MptB, highlighting the role of lipoproteins in regulating key cell wall biosynthetic pathways in these bacteria.[LpqW] (Mus musculus) PubMed

 10671.

SYP121 SNARE contributes to the regulation of the cell osmotic homeostasis. [SYP121] (Mus musculus) PubMed

 10672.

RAF1 (RUBISCO ACCUMULATION FACTOR1) is predominantly expressed in bundle sheath chloroplasts, consistent with a Rubisco accumulation function. [RAF1] (Mus musculus) PubMed

 10673.

Ydr370C has robust decapping activity on RNAs with unmethylated caps, but it has no detectable pyrophosphohydrolase activity (Ydr370C). (Mus musculus) PubMed

 10674.

This paper is the first report to describe the involvement of TaBTF3 in maintaining the normal plant mesophyll cell structure.[TaBTF3] (Mus musculus) PubMed

 10675.

Integrase and reverse transcriptase physically interacts with PML proteins during Moloney murine leukemia virus infection [integrase, reverse transcriptase]. (Mus musculus) PubMed

 10676.

O1 (Opaque1) is myosin XI motor protein that affects zein protein body biogenesis. [Opaque1] (Mus musculus) PubMed

 10677.

SDG724 is a major HMTase responsible for H3K36 methylation. Mutations in SDG724 delay flowering irrespective of photoperiod.[SDG724; Os09g13740] (Mus musculus) PubMed

 10678.

Staphylococcus aureus extracellular adherence protein triggers TNFalpha release, promoting attachment to endothelial cells via protein A [Eap] (Mus musculus) PubMed

 10679.

The tRNA recognition mechanism of TrmFO, is reported.[TrmFO] (Mus musculus) PubMed

 10680.

Prx2 is a residential scavenger of peroxides endogenously generated, whereas Prx1 is an occasional scavenger of peroxides exogenously encountered.[Prx1, Prx2] (Mus musculus) PubMed

 10681.

Tunicate1 (Tu1) is involved in inflorescence architecture by promoting indeterminate cell fate. [Tu1] (Mus musculus) PubMed

 10682.

crystal structure of CYP105N1 (CYP105N1) (Mus musculus) PubMed

 10683.

evidence presented suggesting that NdgR is an activator of methionine (and likely cysteine) biosynthesis [NdgR] (Mus musculus) PubMed

 10684.

Asn-460 in the V5 region is a critical determinant of sensitivity to VRC01, a a broadly neutralizing monoclonal antibody.[gp120] (Mus musculus) PubMed

 10685.

data highlight for the first time the role of the RNA-binding protein CspR as a regulator in E. faecalis and its requirement in stress response and virulence in this important human pathogen. [CspR] (Mus musculus) PubMed

 10686.

In the physiological range, oxygen or downstream metabolic effectors control the timing of developmental progression via activation of newly synthesized Skp1 in Dictyostelium discoideum AX3. {Skp1] (Mus musculus) PubMed

 10687.

The results indicated that OsLEA3-2 plays an important role in tolerance to abiotic stresses (OsLEA3-2). (Mus musculus) PubMed

 10688.

The findings suggest that the PbPga1gene codifies for a cell surface glycoprotein, probably attached to a GPI-anchor, which may play a role in P. brasiliensis cell wall morphogenesis and infection (PbPga1). (Mus musculus) PubMed

 10689.

presence of Smad4 protein in testicular cells provides molecular and morphological evidence for TGF-beta signal transduction during testicular development and spermatogenesis [smad4] (Mus musculus) PubMed

 10690.

results show that pATOM36 is a novel component associated with the archaic translocase of the outer mitochondrial membrane (ATOM) complex that promotes the import of a subpopulation of proteins into the mitochondrial matrix [ATOM36] (Mus musculus) PubMed

 10691.

The the CENP-B subunit, Abp1, functions as a recruiter of the Ku complex, which in turn loads the genome-organizing machinery condensin to retrotransposons.(Abp1 protein) (Mus musculus) PubMed

 10692.

Corynebacterium glutamicum Ppm1 (Ppm synthase) and Ppm2 (lipoprotein N-acyl transferase) operate in a common biosynthetic pathway in which lipoprotein N-acylation and glycosylation are tightly coupled. [Ppm1], [Ppm2] (Mus musculus) PubMed

 10693.

The FtsZ2 is the primary determinant of chloroplast Z-ring structure, whereas FtsZ1 facilitates Z-ring remodeling. (FtsZ2 (Mus musculus) PubMed

 10694.

Atoh1 is a gene critical for promoting repair/regeneration of stereocilia and maintaining injured hair cells in the adult mammal cochlea. [Atoh1] (Mus musculus) PubMed

 10695.

the kinetic behavior of WrbA [WrbA] (Mus musculus) PubMed

 10696.

SarA plays a direct role in the regulation of fmtA expression via binding to the fmtA promoter [SarA][fmtA] (Mus musculus) PubMed

 10697.

a novel negative regulator of nitrosative stress response [Cwt1p] (Mus musculus) PubMed

 10698.

Results show that fission yeast SpSec3 plays a canonical role in the tethering of secretory vesicles with the plasma membrane and also has an unexpected function of in actin assembly (sec3). (Mus musculus) PubMed

 10699.

The Drg1 specifically and exclusively extracted Rlp24 from purified pre-60S particles.(Drg1; Rlp24) (Mus musculus) PubMed

 10700.

analysis of pfhrp2 gene deletions and cross-reactions in the Peruvian Amazon [pfhrp2] (Mus musculus) PubMed

 10701.

The de novo F-actin assembly at the division site and directed transport of F-actin cables assembled elsewhere can contribute to ring assembly.(F-actin) (Mus musculus) PubMed

 10702.

analysis of pfhrp2 gene deletions and cross-reactions in the Peruvian Amazon [pfhrp2] (Mus musculus) PubMed

 10703.

Peflin was identified as an interaction partner of TRPN1 in vitro. [TRPN1 protein, Xenopus laevis] (Mus musculus) PubMed

 10704.

the evolution of human influenza A(H3N2) viruses since 1968 has produced a virus with a low propensity to bind human receptor analogs, and this loss of avidity correlates with the marked reduction in A(H3N2) virus disease impact in the last 10 yrs (Mus musculus) PubMed

 10705.

TRICOT encodes an AMP1-related carboxypeptidase that regulates root nodule development and shoot apical meristem maintenance in Lotus japonicus [TRICOT] (Mus musculus) PubMed

 10706.

The cloning and functional characterization of a major grain length quantitative trait loci, qGL3, which encodes a putative protein phosphatase with Kelch-like repeat domain (OsPPKL1), is reported.[OsPPKL1] (Mus musculus) PubMed

 10707.

The CSI1 protein localized to the site of centromere attachment and interacted with both the inner nuclear envelope SUN domain protein Sad1 and centromeres.(Csi1) (Mus musculus) PubMed

 10708.

The BreR consensus sequence AANGTANAC-N(6)-GTNTACNTT overlaps the -35 region at both promoters, implying that the repression of gene expression is achieved by interfering with RNA polymerase binding at these promoters.[BreR] (Mus musculus) PubMed

 10709.

Competition between anion binding and dimerization modulates PI-PLC enzymatic activity. [PI-PLC ] (Mus musculus) PubMed

 10710.

A newly described xylanase XYN IV from Trichoderma reesei behaves as a typical endo-acting xylanase. [XYN IV] (Mus musculus) PubMed

 10711.

mouse cytomegalovirus m152/gp40 interaction with RAE1gamma structural analysis reveals a paradigm for MHC/MHC interaction in immune evasion (Mus musculus) PubMed

 10712.

by stabilizing key elements in Bax needed to unravel for its MOM insertion and oligomerization, vMIA prevents these important steps in apoptosis (Mus musculus) PubMed

 10713.

The sdiA mutant of E. cloacae GS1 was insensitive to N-acyl homoserine lactone (NAHL), suggesting that this NAHL-induced inhibition of root colonization and biofilm formation is SdiA dependent[strain GS1; sdiA] (Mus musculus) PubMed

 10714.

AmyR plays an important role in regulating exopolysaccharide production, and thus virulence in E. amylovora.[AmyR] (Mus musculus) PubMed

 10715.

The expression and interaction of ribosomal protein S1 and ribosomal protein S2 associated with a single thermosensitive mutation are reported. (Mus musculus) PubMed

 10716.

The effects of an rpoC mutation on the defects in cell division induced by Fst toxin in E. faecalis are reported.[rpoC; Fst] (Mus musculus) PubMed

 10717.

Characterization of the Staphylococcus aureus rRNA methyltransferase encoded by orfX, the gene containing the staphylococcal chromosome Cassette mec (SCCmec) insertion site [orfX] (Mus musculus) PubMed

 10718.

Deletion of both YOP1 and SEY1 , not only perturbed endoplasmic reticulum morphology more severely than in sey1 or yop1 strains, but also abrogated the fluconazole-induced disomy.[YOP1, SEY1] (Mus musculus) PubMed

 10719.

Overexpression of EsaA increases activation of secondary metabolite production. [EsaA] (Mus musculus) PubMed

 10720.

Protein complex SaePQ activates the phosphatase activity of SaeS in the SaeRS two-component system. [SaeP, SaeQ] (Mus musculus) PubMed

 10721.

The authors report that miR-181 can directly impair porcine reproductive and respiratory syndrome virus infection. (Mus musculus) PubMed

 10722.

The glycosylation of Flo11 contributed to its stability.[Flo11] (Mus musculus) PubMed

 10723.

In summary, these studies suggest that ORF2 promotes a mature neuronal phenotype that enhances the survival of infected neurons and consequently increases the pool of latently infected neurons.[ORF2] (Mus musculus) PubMed

 10724.

These results indicated that Nsp1beta of porcine reproductive and respiratory syndrome virus is able to bind and interact with cellular PCBP2 strongly in both the infected cells and plasmid transfected cells.[Nsp1beta] (Mus musculus) PubMed

 10725.

Both centrin2 and centrin3 are involved in organelle segregation similar to centrin1 as was previously observed. [TbCen2], [Tbcen3] (Mus musculus) PubMed

 10726.

A modest amplification in melanopsin-using receptors is therefore apparent in early chordates [melanopsin] (Mus musculus) PubMed

 10727.

the functional dependence between the two linkers and the essential role of the linkers in passing signal information from one domain to another [CheA] (Mus musculus) PubMed

 10728.

These results are compatible with the hypothesis that the air-liquid biofilm formation depends on FLO11 transcription levels as well as on fatty acids biosynthesis.[FLO11] (Mus musculus) PubMed

 10729.

Taken together, these results suggest that hepatitis C virus NS4B induces apoptosis through the mitochondrial death pathway.[NS4B] (Mus musculus) PubMed

 10730.

The necessary and sufficient function of Oct4 in promoting pluripotency is to activate specific target genes.[XlPou91] (Mus musculus) PubMed

 10731.

The coordinated effects on inhibition of protease activity and stimulation of ATPase activity raise the possibility that RNA serves as a regulatory switch for the two processes.[NS3] (Mus musculus) PubMed

 10732.

The composition of the medium determines which extracellular signal (XIP or CSP) elicits a response from comX. [ComX] (Mus musculus) PubMed

 10733.

Exogenous iron could suppress the sensitivity of the mrs4Delta/Delta mutant to oxidants and most metal ions, suggesting that the role of CaMrs4 is partially mediated by iron availability.[mrs4] (Mus musculus) PubMed

 10734.

investigation of temporal/spatial relationship of expression of Cdx-2 (caudal type homeobox transcription factor 2), Oct-4 (octamer-binding protein 4), and histone H4 in morula/blastocysts [caudal type homeobox 2 AND HIST4/histone H4] (Mus musculus) PubMed

 10735.

LdHAT1 is regulated by S-phase cell cycle kinase LdCyc1-CRK3.[LdHAT1,LdCyc1-CRK3} (Mus musculus) PubMed

 10736.

The authors provide evidence that ICP27 protein encoded by bovine herpesvirus type 1, a viral early protein that shuttles between the nucleus and cytoplasm inhibits transcriptional activity of two bovine IFN-beta gene promoters (IFN-beta1 and IFN-beta3).[ICP27] (Mus musculus) PubMed

 10737.

Histone H3 arginine 2 dimethylation lysine 4 trimethylation, not simply H3lysine 4 trimethylation alone, is the mark of active promoters.[Histone H3] (Mus musculus) PubMed

 10738.

Inactivation of sarA induced biofilm formation via overexpression of the Embp.[SarA,Embp ] (Mus musculus) PubMed

 10739.

a novel function of HBx in promoting epithelial-mesenchymal transition through Snail protein stabilization by activating PI3K/AKT/GSK-3beta signaling, thus facilitating tumor invasion and metastasis during hepatocellular carcinoma progression. [HBx protein] (Mus musculus) PubMed

 10740.

The PDZ binding motifs within NS5 were mutated individually and in concert and the results show that the replication rate was impaired in all mutants, which indicates that PDZ dependent host interactions influence virus replication.[NS5] (Mus musculus) PubMed

 10741.

crystal structure of a complex of BcsA and BcsB from Rhodobacter sphaeroides containing a translocating polysaccharide [BcsA & BcsB] (Mus musculus) PubMed

 10742.

Here, the authors show that cowpox virus-encoded OMCP binds the NKG2D homodimer as a monomer and competitively blocks host ligand engagement.[OMPC] (Mus musculus) PubMed

 10743.

These results suggest that the Japanese encephalitis virus core protein circumvents translational shutoff by inhibiting stress granule formation through an interaction with Caprin-1 and facilitates viral propagation in vitro and in vivo.[core protein] (Mus musculus) PubMed

 10744.

In the present study, the authors provide evidence that the West Nile virus capsid protein blocks apoptosis through a phosphatidylinositol (PI) 3-kinase-dependent pathway.[capsid protein] (Mus musculus) PubMed

 10745.

Arg283 and Ile287 may be implicated in ribonucleotide binding and positioning of the template base in the active site, while Arg285 appears to be involved directly in the selection of cognate nucleotide.[NS5B] (Mus musculus) PubMed

 10746.

Here the authors identify serine 222 of genotype 2a NS5A as a phosphorylation site that functions as a negative regulator of RNA replication.[NS5A] (Mus musculus) PubMed

 10747.

These results demonstrate that the acidic polymerase protein (PA) gene of VN3028IIcl2 affects cytokine production in human macrophages and virulence in mice. [PA] (Mus musculus) PubMed

 10748.

The C-terminal region of NSm, which contains a basic amino acid cluster and a putative transmembrane domain, targeted the protein to the mitochondrial outer membrane and exerted antiapoptotic function.[NSm] (Mus musculus) PubMed

 10749.

The authors showed that Arf1 interacted with the viral p27 replication protein within the virus-induced large punctate structures of the endoplasmic reticulum membrane.[p27] (Mus musculus) PubMed

 10750.

The authors confirmed a physical interaction between LITAF and frog virus 3 75L but found that this interaction was not mediated by two PPXY motifs in the N terminus of LITAF.[75L] (Mus musculus) PubMed

 10751.

pks12 and pks11 are probably responsible for sequential use in the biosynthesis of mitorubrinol and mitorubrinic acid.[pks12, pks11] (Mus musculus) PubMed

 10752.

Furthermore, the authors found that a single change of aspartic acid to glutamic acid in the CW3 strain of murine norovirus NS1/2 was sufficient for persistence.[NS1/2] (Mus musculus) PubMed

 10753.

The PaAlr1(Delta) mutants showed sensitivity to deprivation and excess Mg(2+) and Ca(2+).[Alr1] (Mus musculus) PubMed

 10754.

These data reveal an indirect role for miR-K12-11 of Kaposi's sarcoma-associated herpesvirus in the regulation of DUSP1 and downstream pathogenesis.[miR-K12-11] (Mus musculus) PubMed

 10755.

Overall, these data point out that ionic interactions form a major component of the binding interface between CCPH and its interacting partners.[CCPH] (Mus musculus) PubMed

 10756.

EPG-9 forms a complex with EPG-1 in the aggrephagy pathway in C. elegans.[EPG-9, EPG-1] (Mus musculus) PubMed

 10757.

DesA encodes a novel LDC and are involoved in siderophore biosynthesis. [DesA] (Mus musculus) PubMed

 10758.

[EhNCABP166] EhNCABP166 as a protein containing functional nuclear localization signals and a nuclear export signal (Mus musculus) PubMed

 10759.

Mac1 is a transcription factor which regulated high affinity copper transport. (Mac1) (Mus musculus) PubMed

 10760.

results suggest that the antisense small RNA 5'ureB-sRNA downregulates ureAB expression by enhancing transcription termination 5' of ureB [ureB] (Mus musculus) PubMed

 10761.

These data indicate that HCV glycoprotein E1 can also affect the fusion protein E2 by modulating its recognition by the cellular coreceptor CD81.[E1, E2] (Mus musculus) PubMed

 10762.

Collectively, these findings highlight a stable interaction between p7 and NS2 which is likely crucial for production of infectious hepatitis C virus particles.[p7, NS2] (Mus musculus) PubMed

 10763.

The study used an ATP analogue to modify HCV replicase in order to identify the ATP binding site in the enzyme. [HCV replicase] (Mus musculus) PubMed

 10764.

ac109 affects envelopment of nucleocapsids in the nucleus and the production of infectious budded virus. [ac109] (Mus musculus) PubMed

 10765.

ClpL recognizes primarily soluble but denatured substrates and prevents the formation of large protein aggregates. We also found that in vivo, the C-terminal D2-small domain of ClpL is essential for the observed chaperone activity [ClpL] (Mus musculus) PubMed

 10766.

McsB of the clpC operon was identified as a crucial and necessary component of stress and pathogenicity mechanisms.[mcsB] (Mus musculus) PubMed

 10767.

Data indicate that OsELF3-1 (LOC_Os06g05060) may play a vital role in flowering regulation: [OsELF3-1] (Mus musculus) PubMed

 10768.

Data shows that the U11/U12-31K protein is an indispensible RNA chaperone that functions in U12 intron splicing and for normal development of plants (U11/U12-31K). (Mus musculus) PubMed

 10769.

These results highlight the relevance of cellulose in Salmonella lifestyle switching as an architectural element that is both essential for biofilm development and required, in collaboration with YcgR, for complete motility inhibition.[YcgR] (Mus musculus) PubMed

 10770.

These results highlight the relevance of cellulose in Salmonella lifestyle switching as an architectural element that is both essential for biofilm development and required, in collaboration with YcgR, for complete motility inhibition.[YcgR] (Mus musculus) PubMed

 10771.

mechanistic insights into VldE structure and function [VldE] (Mus musculus) PubMed

 10772.

(PMAT)PMAT was established as an electrogenic transporter and the physiological inside-negative membrane potential as a driving force for PMAT-mediated organic cation transport. (Mus musculus) PubMed

 10773.

Cys703 to Ile or His mutation within Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase ERG7 (ERG7(C703I/H)) generates an unusual truncated bicyclic rearranged intermediate related to iridal-skeleton triterpenoid [ERG7] (Mus musculus) PubMed

 10774.

We have demonstrated that preparations of isolated C-lobe and N-lobe fragments of bovine trasnferrin are capable of binding to the Tb transferring receptor (TfR)in direct and competitive uptake and binding assays. [TfR] (Mus musculus) PubMed

 10775.

Sequencing of the plastid rrn16 gene revealed that spectinomycin resistance is due to mutations in a conserved stem structure of the 16S rRNA.[rrn16] (Mus musculus) PubMed

 10776.

Using molecular dynamics simulations, identified are several conformational events in these simulations, revealing how the intrinsic coupling between the three subdomains (LID, CORE, and NMP) changes during the simulations. [adenylate kinase] (Mus musculus) PubMed

 10777.

These findings suggest that four C-terminal variations of ArsS adds to the complexity of the ArsRS acid adaptation mechanism as a whole and may influence the ability of Helicobacter pylori to persist in the gastric niche for decades.[ArsS] (Mus musculus) PubMed

 10778.

Overall, this study identified specific amino acids in the E2 stem region of importance for hepatitis C virus entry and for production of infectious virus particles.[E2] (Mus musculus) PubMed

 10779.

ORF34 is an essential gene with a possible role in infectious virus production.[ORF34] (Mus musculus) PubMed

 10780.

These results demonstrate that ORF4 is a newly discovered viral protein that is not essential for virus replication but plays a role in suppressing caspase activity and regulating CD4(+) and CD8(+) T lymphocytes during infection.[ORF] (Mus musculus) PubMed

 10781.

These results indicated that KexA is required for normal growth of Aspergillus oryzae and that it might be involved in hyphal branching. (Mus musculus) PubMed

 10782.

Allelism analysis indicated that mlbhl is a new gene, either allelic or closely linked with Pm24.[mlbhl] (Mus musculus) PubMed

 10783.

This is the first report that demonstrates an association of ZmGE2 with embryo to endosperm ratio variation in maize.[ZmGE2] (Mus musculus) PubMed

 10784.

structure of the CyanoP subunit of photosystem II from the cyanobacterium Synechocystis sp. PCC 6803 has been determined in solution by Nuclear Magnetic Resonance spectroscopy [CyanoP] (Mus musculus) PubMed

 10785.

These results indicated that LplR is a negative regulator in L-pantoyl lactone dehydrogenase expression.[LplR] (Mus musculus) PubMed

 10786.

Data indicate that the level of Lis1 (DQ647383; lissencephaly protein 1-like) in flagella was dependent on the presence of the outer arm dynein alpha heavy chain/light chain 5 thioredoxin unit: [Lis1] (Mus musculus) PubMed

 10787.

Conformational interdependence was identified between LAP1 (LCCL-lectin adhesive-like domain protein 1)and LAP3 that stabilizes the molecules when they interact and promotes the assembly of the functional LCCL protein complex. [LAP1, LAP3] (Mus musculus) PubMed

 10788.

The glucan 1,3-beta-glucosidase A gene (exgA) from Aspergillus oryzae and fused to the Saccharomyces cerevisiae signal peptide (alpha-factor) was expressed under the control of either a constitutive (GAP) or an inducible (AOX1) promoter in Pichia pastoris. (Mus musculus) PubMed

 10789.

demonstrated that changes in the low temperature-induced energy redistribution and regulation of photosystem stoichiometry are acclimatization responses exerted by Synechocystis cells, essentially regulated by CrhR at low temperature (CrhR) (Mus musculus) PubMed

 10790.

This antagonist activity was mapped to the Western equine encephalitis virus capsid gene, which disrupted signal transduction downstream of IRF-3 activation and was independent of capsid-mediated inhibition of host macromolecular synthesis.[capsid] (Mus musculus) PubMed

 10791.

Interestingly, the Q136K mutation strongly impairs viral fitness in the guinea pig transmission model.[neuraminidase] (Mus musculus) PubMed

 10792.

The two component system PrlS/PrlR controls stress adaptation and persistence in mice [Prls, PrlR] (Mus musculus) PubMed

 10793.

The putative 5PTase, encoded by D50, is essential for IM formation, including the direction of cell division, deposition of cell wall pectins and control of actin organization. [Dwarf50] (Mus musculus) PubMed

 10794.

ATP-binding casette protein subfamily C transproter (ABCC9) gene is the first gene identified in Leishmania where its deletion results in hypervirulence. [ABCC9] (Mus musculus) PubMed

 10795.

Deletion of manB increased sensitivity to chloramphenicol. [manB] (Mus musculus) PubMed

 10796.

Tom40 crossed the outer membrane and/or inner membrane even in the presence of various sorting signals.[Tom40] (Mus musculus) PubMed

 10797.

ACTIN-RELATED PROTEIN COMPONENT1 (ARPC1) is essential for rhizobial infection but not for arbuscular mycorrhiza symbiosis.[ARPC1] (Mus musculus) PubMed

 10798.

the chimeric receptor consisting of CEBiP and Pi-d2 functions as a receptor for chitin oligosaccharides and CEBiP-based chimeric receptors fused with other RLKs may also act as functional receptors. [CEBiP, Pi-d2 ] (Mus musculus) PubMed

 10799.

Three components of a GTPase module--the Ypt1 activator, Trs85-containing TRAPP complex, Ypt1, and the Atg11 effector--interact on the phagophore assembly site(PAS) and are required for PAS formation during selective autophagy.[Ypt1] (Mus musculus) PubMed

 10800.

Authors demonstrated that the Helicobacter pylori HspB protein interferes with Nrf2/Keap1 pathway.[HspB] (Mus musculus) PubMed

 10801.

AphA-mediated repression of ahpA, qrr2-4, and opaR was characterized in V. parahaemolyticus.[AphA] (Mus musculus) PubMed

 10802.

Arginine (R60) also plays an important role in S. typhimurium SdiA binding with its acyl homoserine lactones auto inducers.[SdiA] (Mus musculus) PubMed

 10803.

A requirement for the septin Shs1 and the septin-associated kinase Gin4 for the localization and in vivo activity of the budding yeast Bnr1, is described.[Gin4, Shs1] (Mus musculus) PubMed

 10804.

Vps27 phosphorylation by Pkh1/2 kinases regulates the coordinated cascade of endosomal sorting complex required for transport complex recruitment at the endosomal membrane.[PKH2, Vps27] (Mus musculus) PubMed

 10805.

Caenorhabditis elegans homolog of the Opitz syndrome gene, madd-2/Mid1, regulates anchor cell invasion during vulval development [madd-2] (Mus musculus) PubMed

 10806.

Data suggest that Trp159 and Asp126 are individually critical for retaining a bimetallic center and thereby for function of arginase. [arginase; rocF] (Mus musculus) PubMed

 10807.

Data suggest that proper dimerization of biotin carboxylase domain/subunit in tetramer of pyruvate carboxylase is important for catalytic activity. [biotin carboxylase AND pyruvate carboxylase] (Mus musculus) PubMed

 10808.

determined crystal structures for the PixJ GAF domain in its green-absorbing 15E state (PixJ) (Mus musculus) PubMed

 10809.

NOP-1 functions in parallel with CYK-4 to promote RhoA activation.[NOP-1, RhoA] (Mus musculus) PubMed

 10810.

Mia40 in cooperation with Erv1 promotes the formation of two disulfide bonds in the substrate protein, ensuring the efficiency of oxidative folding in the intermembrane space of mitochondria.[Mia40] (Mus musculus) PubMed

 10811.

LjSYP71, a component of the SNARE complex that is expressed in vascular tissues, plays an essential role in symbiotic nitrogen fixation in Lotus japonicus nodules.[SYP71] (Mus musculus) PubMed

 10812.

Residue Y173 of OsSgt1 played a vital role in the interactions with OsHsp90.[Sgt1, HSP90] (Mus musculus) PubMed

 10813.

DEES1 (DEFECT IN EARLY EMBRYO SAC1) is involved in the regulation of embryo sac development. [DEES1] (Mus musculus) PubMed

 10814.

CFO1 (CHIMERIC FLORAL ORGANS1) is an important regulator of floral organ identity in rice. [CFO1] (Mus musculus) PubMed

 10815.

different levels of BMP signaling regulate Nodal expression by a balance between BMP-pSMAD1/4 signaling and NODAL-pSMAD2/4 signaling [SMAD4] (Mus musculus) PubMed

 10816.

VvPIP2;4N is a root-specific grapevine aquaporin. Upon water stress, the overexpression of VvPIP2;4N induced a surge in leaf abscisic acid content and a decrease in stomatal conductance and leaf gas exchange. [VvPIP2;4N] (Mus musculus) PubMed

 10817.

Infection of beta interferon (IFN-beta)-deficient Vero cells indicated a role for the NS2A protein in interferon-independent apoptotic cell death.[NS2A] (Mus musculus) PubMed

 10818.

Hepatitis C virus NS5A repressed p53 expression, which was followed by a subsequent decrease in GADD45alpha expression, which triggered cellular proliferation.[NS5A] (Mus musculus) PubMed

 10819.

manE removes a single mannose residue from Man9GlcNAc2, generating Man8GlcNAc2 isomer B[manE] (Mus musculus) PubMed

 10820.

The structure of Cap32/34 from Dictyostelium discoideum allowed a detailed analysis and comparison between the cytoplasmic and sarcomeric variants of capping protein.[Cap32/34] (Mus musculus) PubMed

 10821.

M. perniciosa produces a methanol oxidase(MOX) that is secreted into the extracellular space.[MOX] (Mus musculus) PubMed

 10822.

These data suggest that in spite of the differences in morphology and composition of the Sindbis- and Venezuelan equine encephalitis virus-specific nsP3 complexes, it is likely that they have similar functions in virus replication.[nsP3] (Mus musculus) PubMed

 10823.

Using a yeast two-hybrid screen, authors identified poly(C)-binding protein 1 (PCBP1) as a novel interacting partner of the classical swine fever virus N(pro) protein.[N(pro)] (Mus musculus) PubMed

 10824.

These data suggest that in spite of the differences in morphology and composition of the Sindbis- and Venezuelan equine encephalitis virus-specific nsP3 complexes, it is likely that they have similar functions in virus replication.[nsP3] (Mus musculus) PubMed

 10825.

MYB30-B protein can improve drought stress tolerance during the germination and the seedling stages. [MYB30-B] (Mus musculus) PubMed

 10826.

Binding of ABI4 to a CACCG motif mediates the ABA-induced expression of the SSI gene in endosperm.[ABI4] (Mus musculus) PubMed

 10827.

Overexpression of starch synthase IIa in endosperm affects the solubility and crystallinity of the storage alpha-glucan. (Mus musculus) PubMed

 10828.

The biochemical and structural characterization of StAckA reported here provides insights into the biochemical specificity, overall fold, thermal stability, molecular basis of ligand binding and inter-domain motion in AckA family of enzymes.[AckA] (Mus musculus) PubMed

 10829.

The first crystal structure of HutZ in a homodimer determined at 2.0 A resolution, is reported.[HutZ] (Mus musculus) PubMed

 10830.

GW2 regulates grain size possibly by controlling endosperm cell number. [GW2] (Mus musculus) PubMed

 10831.

HSBP1 and HSBP2 are negative regulators of heat shock response. [HSBP1, HSBP2] (Mus musculus) PubMed

 10832.

Gal-3 is essential for ROS generation by neutrophils in the initial acute phase of T. gondii infection and this phenomenon may constitute an attempt to control parasite growth during in vivo infection with the T. gondii virulent strain. [gal-3] (Mus musculus) PubMed

 10833.

Mutants lacking AfIlv3A exhibit reduced levels of virulence in murine infection models (AfIlv3A). (Mus musculus) PubMed

 10834.

This paper provides evidence that while goa-1 and egl-30 are important for normal daf-7 expression, mutations in these genes are not sufficient to disrupt dauer formation.[daf-7, goa-1] (Mus musculus) PubMed

 10835.

Both IAP2 and IAP3 induced apoptosis in Ld652Y cells in a transient expression assay.[IAP2 and IAP3] (Mus musculus) PubMed

 10836.

The NMR structure and substrate binding region of the C39-like domain of the hemolysin A carrier HlyB. [HlyB] (Mus musculus) PubMed

 10837.

The p55 domain, composed primarily of beta-helical structures, localizes to the peripheral arms, while the p33 domain consists of two globular densities that localize within the center of the complexes.[VacA] (Mus musculus) PubMed

 10838.

The enzyme structure reveals that the Cel6B enzyme has a much longer substrate-binding site than its fungal GH6 counterparts.[Cel6B] (Mus musculus) PubMed

 10839.

A three dimensional model of the 12 kDa ES protein, was constructed.[ES] (Mus musculus) PubMed

 10840.

The Enterohaemorrhagic Escherichia coli O157:H7 single EspF(U) repeat forms a high-affinity trimolecular complex with N-WASP and IRTKS. [EspF] (Mus musculus) PubMed

 10841.

Hog1 and RNA Pol II colocalize to open reading frames that bypass global transcriptional repression. (Mus musculus) PubMed

 10842.

DnaK deletion caused a reduction in the ability of S. aureus to make biofilms and its adherence to eukaryotic cells. [Dnak] (Mus musculus) PubMed

 10843.

the effectiveness of aldehyde dehydrogenase (ALDH) from Saccharomyces cerevisiae as a catalyst for the conversion of acetaldehyde into its physiologically and biologically less toxic acetate [ALDH] (Mus musculus) PubMed

 10844.

We show that postembryonic arborization and neurosecretory terminal targeting of the C. elegans NSM neuron is dependent on the Netrin receptor UNC-40/DCC (Mus musculus) PubMed

 10845.

PfRuvB1 contains DNA helicase activity and translocates preferentially in 5' to 3' direction (PfRuvB1). (Mus musculus) PubMed

 10846.

KP6 is neutral protein composed of two subunits: KP6alpha and KP6beta. KP6alpha is responsible for targeting while KP6beta is cytotoxic.[KP6alpha and KP6beta] (Mus musculus) PubMed

 10847.

The pore-forming, cholesterol-dependent cytolysin pneumolysin (PLY), a major neurotoxin of Streptococcus pneumoniae, has the capacity to bind actin directly and to enhance actin polymerisation in vitro.[PLY] (Mus musculus) PubMed

 10848.

Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis [LXRbeta] (Mus musculus) PubMed

 10849.

The structure of T.th. RuvC homodimer shows distinct asymmetry near the dimer interface, in the region harboring catalytically important aromatic residues (RuvC). (Mus musculus) PubMed

 10850.

The results indicate that the overexpression of aldolase A and cytokeratin 19 reflects the presence of neoplastic cells in the lungs of ovine pulmonary adenocarcinoma affected sheep.[cytokeratin 19] (Mus musculus) PubMed

 10851.

The substrate interacting residues in ck1alpha have been identified using the structural model of kinase - substrate peptide. The PKR interacting NS5A 1b residues have also been predicted.[NS5A] (Mus musculus) PubMed

 10852.

Authors postulate that the observed intragenic complementation groups define three distinct and genetically separable functions of NS5A in RNA replication.[NS5A] (Mus musculus) PubMed

 10853.

Authors report that mitochondrial-localized m41.1 (vIBO) is required for optimal viral replication in macrophages and has a modest impact on dissemination in infected mice.[m41.1] (Mus musculus) PubMed

 10854.

The penultimate interaction authors detected involves the conserved residue F402, which has hydrophobic contacts with a conserved surface on domain II.[E] (Mus musculus) PubMed

 10855.

hpyAVIBM presents an interesting example of allelic variations in H. pylori where changes in the nucleotide sequence result in proteins with new properties. (AVIBM) (Mus musculus) PubMed

 10856.

H. pylori-mediated cleavage of cytokeratin 18 (CK18) appeared proportional to the number of CagA EPIYA-C and CM motifs, which seemed to be downplayed in the presence of EPIYA-B motifs [CagA] (Mus musculus) PubMed

 10857.

RNA interference-mediated down-regulation of Glucan, Water-Dikinase (GWD), under the control of an endosperm-specific promoter, resulted in a decrease in starch phosphate content and an increase in grain size.[GWD] (Mus musculus) PubMed

 10858.

The results of field evaluations of rice overexpressing OsNAC9, a member of the rice NAC domain family, are presented.[OsNAC9] (Mus musculus) PubMed

 10859.

non-optimal codon usage of frq is essential for its circadian clock function; this study provides an example of how non-optimal codon usage functions to regulate protein expression and to achieve optimal protein structure and function [frq] (Mus musculus) PubMed

 10860.

Analysis of citrus leaves infiltrated with Hpa1 revealed alterations in mesophyll morphology caused by the presence of cavitations and crystal idioblasts.[Hpa1] (Mus musculus) PubMed

 10861.

ATP is sufficient for the closure of MalK and for the conversion of MalFG to the outward facing state.[MalFGK2] (Mus musculus) PubMed

 10862.

Estradiol E2-induced up-regulation of beta-defensin 1 (SBD1) expressions were g-protein-coupled receptor-dependent during prophase and estrogen receptor-dependent during later-stage in ovine oviduct epithelial cells.[SBD-1] (Mus musculus) PubMed

 10863.

The finding of important stress-related cis-acting elements in the promoter region of rice ATG6 genes demonstrated their involvement in abiotic stress responses.[ATG6a, ATG6b, ATG6c] (Mus musculus) PubMed

 10864.

Role of Helicobacter pylori methionine sulfoxide reductase in urease maturation (Mus musculus) PubMed

 10865.

Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment (strain BY4741/42). [Ist2] (Mus musculus) PubMed

 10866.

structual basis of VAPC binding to HCV NS5B [NS5B] (Mus musculus) PubMed

 10867.

TbTim50 plays additional roles in mitochondrial activities besides preprotein translocation.[Tim50] (Mus musculus) PubMed

 10868.

The data presented here suggest that extracellularly targeted MtDef4.2 is sufficient to provide strong resistance to the biotrophic oomycete, consistent with the extracellular lifestyle of this pathogen.[MtDef4.2] (Mus musculus) PubMed

 10869.

Data suggest that proline/alanine transporter LdAAP24 (amino acid permease 24; GenBank Acc # EU391425) plays a key role in parasite adaptation to its varying environments: [AAP24] (Mus musculus) PubMed

 10870.

The SPOR domain is important for multiple activities associated with DamX. [DamX] (Mus musculus) PubMed

 10871.

Ypi1 plays an important role in the morphogenesis checkpoint, possibly by regulating Swe1.[Ypi1, Glc7] (Mus musculus) PubMed

 10872.

The function of the maturational refolding of the beta-hairpin in capsid protein (EIAV-CA) assembly is to extend helix alpha1 at the N-terminus to enhance the CA(N) oligomerization along the capsid assembly core interface.[EIAV-CA] (Mus musculus) PubMed

 10873.

The regulation of DnaA couples chromosomal replication to cell growth.[DnaA] (Mus musculus) PubMed

 10874.

structures of DTBS from Helicobacter pylori (hpDTBS) bound with cofactors and a substrate analog, and described its unique characteristics relative to other DTBS proteins.(DTBS)) (Mus musculus) PubMed

 10875.

p17 positively regulates phosphatase and tensin deleted on chromosome 10 (PTEN), AMP-activated protein kinase (AMPK), and dsRNA dependent protein kinase RNA (PKR)/eIF2alpha signaling pathways.[AMPK] (Mus musculus) PubMed

 10876.

The presence of the beta-prism domain-mediated lectin activity is crucial for an efficient interaction of the vibrio cholerae cytolysin toward the target cells. [Cytolysin] (Mus musculus) PubMed

 10877.

AusA was reconstituted in vitro and shown to produce all naturally occurring aureusimines and non-natural pyrazinone products with k(cat) values ranging from 0.4 to 1.3 min(-1). [AusA] (Mus musculus) PubMed

 10878.

Lem3p-Dnf1/2p are involved in transport of the tryptophan permease Tat2p to the plasma membrane.[Lem3, Dnf1, Dnf2, Tat2] (Mus musculus) PubMed

 10879.

ZipA protects FtsZ from degradation by ClpP by making the FtsZ site of interaction unavailable to the ClpX moiety of the ClpXP protease.[ZipA, FtsZ] (Mus musculus) PubMed

 10880.

The data show that the Asn139Cys and Asn139Asp mutations in cytochrome c oxidase result in the same changes of the kinetic and thermodynamic parameters associated with the proton transfer.[cytochrome c oxidase] (Mus musculus) PubMed

 10881.

the present study we characterized PfECT [P. falciparum CTP:phosphoethanolamine CT (cytidylyltransferase)], which we identified as the rate-limiting step of the PE metabolic pathway in the parasite (Mus musculus) PubMed

 10882.

The BmEP80 protein was expressed in the ovary from the 9th day of the pupa stage to eclosion in the wild-type silkworm and is responsible for the "Ming" lethal egg mutant phenotype. (Mus musculus) PubMed

 10883.

Myosin heads bound to oriented actin filaments are highly disordered with respect to the actin filament axis, in contrast to the nearly crystalline order of myosin heads in rigor.[Actin, skeletal muscle] (Mus musculus) PubMed

 10884.

T. gondii cathepsin B protease (TgCPB) does not undergo self-maturation but instead requires the expression of a second papain-family cathepsin protease, TgCPL.[TgCPL, TgCPB] (Mus musculus) PubMed

 10885.

Helices 1, 2, and 7 constitute the extracellular gate of LdNT1.1. [LdNT1.1] (Mus musculus) PubMed

 10886.

The synthesis of response regulators UvrY and CpxR in the two-component signal transducing systems and ribosome recycling factor (RRF) was increased by polyamines at the level of translation.[UvrY, CpxR, RRF] (Mus musculus) PubMed

 10887.

The results show that genes belonging to two different groups, the mammalian-like (Opn4m) and the Xenopus-like (Opn4x) melanopsins have been duplicated in teleosts (Mus musculus) PubMed

 10888.

The NO scavenging resulting from these approaches provoked the downregulation of plant genes involved in nodule development, such as MtCRE1 and MtCCS52A. [MtCRE1 and MtCCS52A] (Mus musculus) PubMed

 10889.

EPOR regulates transcriptome for primary progenitors, including Tnfr-sf13c as a novel mediator of EPO-dependent erythroblast formation.[Tnfr-sf13c] (Mus musculus) PubMed

 10890.

GenK is an active gentisate transporter in Corynebacterium glutamicum ATCC13032. [GenK] (Mus musculus) PubMed

 10891.

Gss1 plays an important role in autophagic degradation of peroxisomes and glucose catabolite repression in P. pastoris.[Gss1] (Mus musculus) PubMed

 10892.

The MtbHLH1 gene is involved in the control of nodule vasculature patterning and nutrient exchanges between nodules and roots. [MtbHLH1] (Mus musculus) PubMed

 10893.

HrpM gene contributes to Xanthomonas citri ssp. citri growth and adaptation in its host plant.[HrpM] (Mus musculus) PubMed

 10894.

Myo1 plays a scaffolding role in the assembly of a cytokinesis machine.[Myo1] (Mus musculus) PubMed

 10895.

work describes the specific and efficient cleavage of IgM by the IdeSsuis (Immunoglobulin M-degrading enzyme of S. suis)protein [Ide(s suis] (Mus musculus) PubMed

 10896.

Reduction of WalK phosphatase activity resulted in nearly 90% phosphorylation to WalR.[WalR] (Mus musculus) PubMed

 10897.

results suggest a mechanism by which selective pressure on the TEP1 gene results in functional variation that may influence the vector competence of A. gambiae towards Plasmodium infection [TEP1] (Mus musculus) PubMed

 10898.

We now demonstrate that Srr1 contributes to Streptococcus agalactiae attachment to human brain microvascular endothelial cells via the direct interaction of its binding region with human fibrinogen. [Srr1] (Mus musculus) PubMed

 10899.

Cloning, expression and enzymatic properties analysis of dihydrofolate reductase gene from the silkworm, Bombyx mori. [BmDHFR] (Mus musculus) PubMed

 10900.

R. jostii RHA1 3-hydroxybenzoate 6-hydroxylase (3HB6H) expressed in Escherichia coli is a homodimer with each 47kDa subunit containing a non-covalently bound FAD cofactor. [3HB6H] (Mus musculus) PubMed

 10901.

YbeY is the only endoribonuclease to be implicated in the critically important processing of the 16S rRNA 3' terminus.[YbeY] (Mus musculus) PubMed

 10902.

In this study, another bacterial peptidoglycan modification enzyme, a putative peptidoglycan O-acetyltransferase (PatA), was identified.[PatA] (Mus musculus) PubMed

 10903.

split-KlDoa10 is encoded as two fragments, with the split occurring between TM2 and TM3. The two fragments assemble into an active ubiquitin-protein ligase.[split-Doa10] (Mus musculus) PubMed

 10904.

characterizeation of inosine monophosphate dehydrogenase (IMPDH) structure and mechanism; study demonstrated that de novo GTP biosynthesis is crucial for cryptococcal virulence factor IMPDH expression and pathogenesis [IMPDH] (Mus musculus) PubMed

 10905.

OsOAT is a target gene of SNAC2 and confers stress tolerance mainly through enhancing ROS-scavenging capacity and Pro pre-accumulation. [OsOAT] (Mus musculus) PubMed

 10906.

CNOT10 may stabilize the interaction between CAF1 and the NOT complex (CNOT10). (Mus musculus) PubMed

 10907.

Analysis of cells expressing BRCA2 variants with altered BRC repeat numbers indicates that the BRC repeat expansion is crucial for RAD51 subnuclear dynamics after DNA damage (BRCA2). (Mus musculus) PubMed

 10908.

Vba5p is a plasma membrane protein involved in amino acid uptake and drug sensitivity [Vba5p] (Mus musculus) PubMed

 10909.

Roles of amino acids in the Escherichia coli octaprenyl diphosphate synthase active site (Mus musculus) PubMed

 10910.

analysis of TFE-induced unfolding of KcsA solubilized by the n-dodecyl beta-d-maltoside (DDM) surfactant [KcsA] (Mus musculus) PubMed

 10911.

VopB1 and VopD1 are essential components of the translocon. [VopB1 and BopD1] (Mus musculus) PubMed

 10912.

WbdD regulates the chain length of the O antigen. [WbdD] (Mus musculus) PubMed

 10913.

findings show that FAM21 drives recycling of the WASH complex after V-ATPase recycling has been completed and that this process is mediated by a capping protein connecting the WASH complex to F-actin via its interaction with FAM21 [FAM21; WASH] (Mus musculus) PubMed

 10914.

[FarA] FarA transcriptional factor would be implicated in the expression of cutL1 and hsbA genes that are required for the degradation of PBSA as well as lipolytic genes such as mdlB and tglA for lipid hydrolysis (Mus musculus) PubMed

 10915.

The mechanisms of product inhibition of Trichoderma reesei tyrosinase (TrT) and the inhibition mechanism of potential inhibitors of TrT. (Mus musculus) PubMed

 10916.

Changes in protein dynamics of the DNA repair dioxygenase AlkB upon binding of Fe(2+) and 2-oxoglutarate. (Mus musculus) PubMed

 10917.

mechanism of regulation of the expression of copA and copB, encoding putative copper-translocating P(1B)-type ATPases in Corynebacterium glutamicum [CsoR][copA][copB] (Mus musculus) PubMed

 10918.

Presentation of five structures of Thermotoga maritima reverse gyrase that reveal a view of two interacting zinc fingers that are crucial for positive DNA supercoiling (reverse gyrase). (Mus musculus) PubMed

 10919.

yeIF4B acts in vivo to promote eIF4F assembly by enhancing a conformation of the HEAT domain of yeast eIF4G conducive for stable binding to eIF4A [eIF4B, eIF4F, eIF4G, eIF4A] (Mus musculus) PubMed

 10920.

The Hsp82 mutant proteins were less severely defective in client binding to a model substrate than the corresponding E. coli HSP90 mutant proteins.[Hsp82] (Mus musculus) PubMed

 10921.

The Hsp82 mutant proteins were less severely defective in client binding to a model substrate than the corresponding E. coli HSP90 mutant proteins.[HSP90] (Mus musculus) PubMed

 10922.

Authors found that crp deletion adversely affected the synthesis of three well-characterized antibiotics in Streptomyces coelicolor: actinorhodin (Act), undecylprodigiosin (Red), and calcium-dependent antibiotic (CDA).[crp] (Mus musculus) PubMed

 10923.

Data suggest that fetal glucose-stimulated secretion of insulin increases with amino acid infusion without changes in beta-cell mass/area or pancreatic islet size, vascularity, or insulin content. [INS; insulin] (Mus musculus) PubMed

 10924.

mechanism underlying HBV x protein-induced specific expression of AFPR in hepatocytes (Mus musculus) PubMed

 10925.

The purified Viral protein 4 has a tubular structure with 25-30 nm in width and about 300 nm in length, as observed by transmission electron microscope. Its endopeptidase activity is characterized. [Viral protein 4] (Mus musculus) PubMed

 10926.

ramRA mutations occurring in clinical fluoroquinolone-resistant Salmonella typhimurium isolates may negatively modulate their invasiveness but this is strain-dependent.[ramA, ramR] (Mus musculus) PubMed

 10927.

LL3 is a transcription factor capable of modulating SRPN6 expression as part of the mosquito anti-Plasmodium immune response. [LL3] (Mus musculus) PubMed

 10928.

The present study identified a Plasmodium falciparum gene, Pfgdv1, that plays a role in early gametocytogenesis. [Pfgdv1] (Mus musculus) PubMed

 10929.

SRP16 may play important roles in sperm storage and honey bee reproduction. [SRP16] (Mus musculus) PubMed

 10930.

Overall, the evidence indicates that ScoC is crucial for the utilization of copper under a low-copper condition and for the activation of the multiple Cu(2+) -containing oxidases that play divergent roles in the complex physiology of Streptomyces.[ScoC] (Mus musculus) PubMed

 10931.

5'-UTR of ybfM is important for chitinase induction in S. marcescens [ybfM] (Mus musculus) PubMed

 10932.

function of Ecl1 in the extension of chronological lifespan is dependent on mitochondrial function [Ecl1] (Mus musculus) PubMed

 10933.

Targeted gene deletion experiments with predicted candidate surface antigens identified SRS29C as an important negative regulator of acute virulence in murine models of Toxoplasma infection.[SRS29C] (Mus musculus) PubMed

 10934.

Molecular models of domain structure of MFE-2 from human and C. elegans lend support to possible structural role of MFE-2 domains including SCP-2L (sterol carrier protein 2-like) domain. [multifunctional enzyme type 2; MFE-2] (Mus musculus) PubMed

 10935.

Ubp2 and Ubp12 recognize distinct ubiquitin chains on Fzo1 that have opposing effects on mitochondrial fusion.[Ubp2, Ubp12, Fzo1] (Mus musculus) PubMed

 10936.

the type 1 pneumococcal pilus can activate cells via TLR2, and the ancillary pilus subunit RrgA is a key component of this activation [RrgA] (Mus musculus) PubMed

 10937.

Myb-domain protein Teb1 controls histone levels and centromere assembly in fission yeast.[Teb1] (Mus musculus) PubMed

 10938.

[aox1] the putative HSE and STRE in the upstream region of aox1 directly or indirectly respond to heat shock, oxidative, and osmotic stresses (Mus musculus) PubMed

 10939.

We report here that Pc16p and Pc17p are involved in the metabolism of the branched storage polysaccharide glycogen under certain conditions (PCL7 and PCL6) (Mus musculus) PubMed

 10940.

Thus, IME2 kinase function has evolved following the divergence of S. cerevisiae and N. crassa and provides insight into the evolution of kinases and their regulatory targets (Mus musculus) PubMed

 10941.

These results suggest that the two component YpdA/YpdB contributes to nutrient scavenging before entry into stationary phase.[YpdA; YpdB] (Mus musculus) PubMed

 10942.

The characteristics of CesT with respect to effector binding, effector recruitmen to the type III secretion system, and effector translocation in to host cells is reported[CesT] (Mus musculus) PubMed

 10943.

Cry1 may play roles in switching on the estrous and seasonal reproduction. [Cry1] (Mus musculus) PubMed

 10944.

Loss of the sflA gene is responsible for the suppressor phenotype and the wild-type SflA protein plays a role in preventing polar-type flagella from forming on the lateral cell wall.[sflA] (Mus musculus) PubMed

 10945.

Although YBR159W localizes to the endoplasmic reticulum membrane, subcellular fractionation experiments show that a fraction of eIF2B cofractionates with lipid membranes in a YBR159W-independent manner.[eIF2B] (Mus musculus) PubMed

 10946.

BCAM0223 protein is a multifunctional virulence factor that may contribute to the pathogenicity of B. cenocepacia [BCAM0223] (Mus musculus) PubMed

 10947.

[YhiM] strain not found YhiM was required for survival at pH 2.5 and for the RpoS, glutamine and lysine-dependent acid resistance pathways but not the arginine-dependent acid resistance pathway (Mus musculus) PubMed

 10948.

Tom1 targets Dia2 for degradation during the cell cycle.[Tom1, Dia2] (Mus musculus) PubMed

 10949.

[AuaA]asparagine, but not the arginine residue in NRxxDxxxD, is important for the enzyme activity of AuaA (Mus musculus) PubMed

 10950.

MicroRNA-450a-3p represses cell proliferation and regulates embryo development by regulating Bub1 expression in mouse. [MicroRNA-450a-3p] (Mus musculus) PubMed

 10951.

H11N1, a low pathogenic virus without any proven evidence to infect mammals, contains a highly potential NS1 gene which might contribute to greater virus virulence in different gene combinations.[NS1] (Mus musculus) PubMed

 10952.

KlSnf2 is involved in the Rag4 glucose signaling pathway.[Snf2] (Mus musculus) PubMed

 10953.

Ammonium permeases Amt1 and Amt2 are required for pseudohyphal growth. [Amt1;Amt2] (Mus musculus) PubMed

 10954.

Guanine nucleotide exchange factor RicA plays a crucial and essential role for growth and development in A. nidulans. [RicA] (Mus musculus) PubMed

 10955.

The small RNA was found to negatively regulate the hfq2 mRNA, through binding to part of the 5'-UTR region of the hfq2 mRNA.[Hfq2] (Mus musculus) PubMed

 10956.

Guanine nucleotide exchange factor RicA is necessary for proper expression and regulation of key developmental regulators that coordinate the formation, integrity, and vitality of spores. [RicA] (Mus musculus) PubMed

 10957.

The genome of both Enterococcus faecalis and Listeria monocytogenes contain a gene that encodes a functional glycerol 3-phosphate cytidylyltransferase.[GCT] (Mus musculus) PubMed

 10958.

The ZmMKK3 gene is a positive regulator of osmotic tolerance and ABA signaling in maize. (Mus musculus) PubMed

 10959.

Indole-3-acetic acid production in developing rice grains is controlled via expression of TAR1 (tryptophan aminotransferase), YUC9 and YUC11 genes.[TAR1;YUC9;YUC11] (Mus musculus) PubMed

 10960.

The interaction with Sla1 is important for normal Las17 recruitment to endocytic sites and efficient endocytosis.[Sla1, Las17] (Mus musculus) PubMed

 10961.

that Sub1 associates with Spt5 and influences Spt5-Rpb1 complex levels and consequently transcription elongation rate.[Spt5, Sub1] (Mus musculus) PubMed

 10962.

Heat shock-triggered rapid increases in calcium signaling , together with OsCaM1-1 expression and its nuclear localization, are important in mediating downstream HS-related gene expression for the acquisition of thermotolerance in rice.[Cam1-1] (Mus musculus) PubMed

 10963.

(CIPK15) is a newly identified positive regulator which is critical to directing the O(2) deficiency signal to the sugar signaling cascade as part of Amy3D (representative Amy3 gene) regulation in rice. (Mus musculus) PubMed

 10964.

Trm112 stabilizes its free methyltransferase partners not engaged with substrate and/or helps to deliver its methyltransferase partners to their substrates.[Trm112] (Mus musculus) PubMed

 10965.

Hog1 modulates Rtg1/3 complex activity by multiple mechanisms in response to stress.[Rtg1, Rtg3] (Mus musculus) PubMed

 10966.

MKK1 null mutants grew normally in culture and were able to establish midgut infections in tsetse at normal rates and intensities, but were incapable of colonising the salivary glands.[MKK1] (Mus musculus) PubMed

 10967.

Two distinct surface regions on cytochrome c have been suggested to mediate cardiolipin acyl chain insertion and this study has probed one of these regions.[Cytochrome c] (Mus musculus) PubMed

 10968.

CCaMK enhances epidermal infection by bacteria. The ccamk-14 mutation is responsible for the symbiosis-defective phenotypes. [CCaMK] (Mus musculus) PubMed

 10969.

Inactivation of the clbA gene abrogated the ability for the strain to induce DNA damage and chromosomal abnormalities in cultured rat intestinal epithelial cells but is required for the probiotic activity of Escherichia coli Nissle 1917. (Mus musculus) PubMed

 10970.

These studies reveal a unique genetic and functional relationship between PerR and PolA1 in streptococci.[PerR; PolA1] (Mus musculus) PubMed

 10971.

The N-terminal domain of E. coli 5'-nucleotidase exhibits significant activity, especially towards substrates with activated phosphate bonds (ATP, ADP, p-nitrophenyl phosphate). [5'-nucleotidase] (Mus musculus) PubMed

 10972.

Authors propose a model for p12 function where the N-terminus of p12 interacts with, and stabilizes, the viral core, allowing the C-terminus of p12 to tether the preintegration complex to host chromatin during mitosis, facilitating integration. (Mus musculus) PubMed

 10973.

Non-phosphorylated RpaB controls cell length and shape and intrinsic regulation may be important to prevent drastic variations in RpaB levels and activity. [RpaB] (Mus musculus) PubMed

 10974.

Identification of an 8-vinyl reductase involved in bacteriochlorophyll biosynthesis in Rhodobacter sphaeroides and evidence for the existence of a third distinct class of the enzyme (Mus musculus) PubMed

 10975.

Up-regulation of Phaeodactylum tricornutum DGAT2B precedes the accumulation of triacylglycerol (TAG) suggesting that the enzyme is involved in TAG biosynthesis. [DGAT2B] (Mus musculus) PubMed

 10976.

These results show that the HBSP protein activates cellular immune responses in hepatitis B virus-infected patients but has probably no prominent role in liver damage.[HBSP] (Mus musculus) PubMed

 10977.

In conclusion, this study demonstrated that the conserved K151 modulates infectious virus production; and loop Lambda2 is essential for the polymerase activity of NS5B.[NS5B] (Mus musculus) PubMed

 10978.

The Rht-1 genes played a major role in the control of physiological responses during K(+) deprivation. [Rht-1] (Mus musculus) PubMed

 10979.

maize lipoxygenase-1 expressed in the cytoplasm plays an important role for the regulation of defense system including the antioxidative enzymes in transgenic rice. [ZmLOX1] (Mus musculus) PubMed

 10980.

Overexpression of OsMADS22 and OsMADS55 in Arabdopsis led to abnormal floral morphologies including leaf-like sepals. Only OsMADS55 expression caused delayed flowering via downregulation of FT and SUPPRESSOR OF SOC1. [OsMADS22 and OsMADS55] (Mus musculus) PubMed

 10981.

Authors report that Plasmodium berghei triose phosphate transporter (TPT) knockout parasites failed to survive.[TPT] (Mus musculus) PubMed

 10982.

These results indicate a rapid divergence of prolamin promoter structures and corresponding DNA binding properties probably due to amplification and dispersal of gene copies into a different chromosomal epigenetic context (Mus musculus) PubMed

 10983.

These results suggest that chloroplast protrusions is one of the pathways of Rubisco exclusion from chloroplasts into the cytoplasm under salinity, and the exclusions could be transported to vacuole for their degradation.[Rubisco] (Mus musculus) PubMed

 10984.

Tab 1 encodes an RNA binding PPPEW/OPR protein that is involved in the translation of the PsaB photosystem I subunit. (Mus musculus) PubMed

 10985.

rgfA gene was expressed during vegetative growth and throughout development, but disruption of this gene resulted in no major alterations in cell growth, macropinocytosis, developmental morphology, or chemotactic movement (Mus musculus) PubMed

 10986.

In conclusion, these data suggest that Leishmania parasites possess a functional platelet-activating factor (PAF) acetylhydrolase, PLA2, and the degradation of PAF or PAF-like lipids is an important step in infection.[PLA2] (Mus musculus) PubMed

 10987.

The plant Hsp90 interaction with microtubules (MT) plays a key role in cellular events, where MT re-organization is needed.[HSP90] (Mus musculus) PubMed

 10988.

The expression of MAP3K5 and miR-BART22 is inversely correlated, suggesting the possibility of MAP3K5 to serve as target gene of EBV miR-BART22 in nasopharyngeal carcinoma. [miR-BART22] (Mus musculus) PubMed

 10989.

The ardD gene, coding for an antirestriction protein, is located within the tniA gene, coding for transposase, on the complementary strand.[ardD] (Mus musculus) PubMed

 10990.

The structural mechanism for allosteric inhibition of DHDPS from the common grapevine, is reported.[DHDPS] (Mus musculus) PubMed

 10991.

ArtB may contribute to pathogenesis independently of the A subunit by promoting and maintaining a strong inflammatory response at the site of infection [ArtB]. (Mus musculus) PubMed

 10992.

Thus, the association of ROP18 with the parasitophorous vacuole membrane, mediated by its N-terminal arginine-rich domain, is critical to its function as a virulence determinant.[ROP18] (Mus musculus) PubMed

 10993.

This study cloning UNC% receptor in sea lamprey and demonistrated An increase in the types of identifiable reticulospinal neurons expressing the UNC5L receptors was observed in adults compared with larvae. (Mus musculus) PubMed

 10994.

A regulatory mechanism is triggered by lipochito-oligosaccharides (Myc-LCOs), that prevents over-colonization of roots by arbuscular mycorrhizal fungi by a mechanism involving miRNA-mediated negative regulation of NSP2. [miR171h] (Mus musculus) PubMed

 10995.

The first detailed characterization of leucine aminopeptidase from S. aureus suggests its importance in survival and pathogenesis. (Mus musculus) PubMed

 10996.

data suggest that LacD.1's adaptation represents a form of neofunctionalization in which duplication facilitated the gain of regulatory function important for growth in tissue and pathogenesis [LacD.1] (Mus musculus) PubMed

 10997.

These data indicate strain variations in PA gene products, which play a major role in suppression of host protein synthesis.[PA] (Mus musculus) PubMed

 10998.

These findings indicate that the H1N1 virus NS1 protein induces G(0)/G(1) cell cycle arrest mainly through interfering with the RhoA/pRb signaling cascade, thus providing favorable conditions for viral protein accumulation and replication.[NS1] (Mus musculus) PubMed

 10999.

Rmn1p is involved in the Rae1-mediated mRNA export pathway;Rmn1 is functionally linked to spnab2[rmn1][spnab2] (Mus musculus) PubMed

 11000.

Penicillium chrysogenum catalase and bovine catalase were found capable to catalyze the electrooxidation of phenol, but differed in the specifics of catalytic action. [catalase] (Mus musculus) PubMed

 11001.

The results suggest that special AT-rich-binding protein 1 functions as a pro-metastatic effector of LMP1 signalling in Epstein-Barr virus-positive nasopharyngeal cancer [SATB1] (Mus musculus) PubMed

 11002.

NS1 protein of the human H3N2 virus interacts primarily via the C-terminal NLS2/NoLS and to a minor extent via the N-terminal NLS1 with the main nucleolar proteins, nucleolin, B23 and fibrillarin.[NS1] (Mus musculus) PubMed

 11003.

H5N1 virus NS1 not only blocks IKKbeta-mediated phosphorylation and degradation of IkappaBalpha in the classical pathway but also suppresses IKKalpha-mediated processing of p100 to p52 in the alternative pathway.[NS1] (Mus musculus) PubMed

 11004.

Three mitochondrial PP2C genes, CaPTC5, CaPTC6 and CaPTC7, interact differentially in the response of C. albicans cells to antifungal drugs and cadmium. [PTC6; PTC7] (Mus musculus) PubMed

 11005.

MPR25 is required for C-U RNA editing of nad5 transcripts in mitochondria. [MPR25] (Mus musculus) PubMed

 11006.

Together, these data support roles for Trichomonas vaginalis tetraspanin 6 (TSP6) in parasite migration in the host and sensory reception during infection.[TSP6] (Mus musculus) PubMed

 11007.

ZnT3 takes part in the regulation of various processes in the gut both in normal physiology & pathological processes. ZNT3 (Mus musculus) PubMed

 11008.

Link between S. aureus antimicrobial resistance, virulence, and host immune responses is described. These effects are at least partly driven by excess capsule expression and can be induced by single-nucleotide substitutions in rpoB and relA. [rpoB][RelA] (Mus musculus) PubMed

 11009.

Pgp4 is a transcriptional regulator of plasmid-encoded pgp3 and multiple chromosomal genes, including the glycogen synthase gene glgA, that are likely important in chlamydial virulence [pgp4; strain L2 and L2R] (Mus musculus) PubMed

 11010.

The involvement of Tyr108 in the enzyme mechanism of the small laccase SLAC from Streptomyces coelicolor was investigated by structural, spectroscopic and kinetics experiments. [SLAC] (Mus musculus) PubMed

 11011.

Competition binding studies confirm that the C-terminal 12 amino acids of VP3 are necessary and sufficient for VP1 binding, while biochemical experiments show that VP3 attachment has no effect on polymerase activity.[VP3] (Mus musculus) PubMed

 11012.

further characterization of Rht8 - physiological analysis and genetic mapping [Rht8] (Mus musculus) PubMed

 11013.

identification of the responsible gene, ftmPT3, for O-prenylation of an aliphatic hydroxy group in verruculogen [ftmPT3] (Mus musculus) PubMed

 11014.

These results reveal that EfaR is an important modulator of E. faecalis virulence and link manganese homeostasis to enterococcal pathogenicity (EfaR). (Mus musculus) PubMed

 11015.

NMR chemical shift perturbation analysis reveals that the N-terminal region of an N serine and arginine-rich linker peptide (residues 198 to 230) binds to the acidic face of nsp3a containing the acidic alpha2 helix. (Mus musculus) PubMed

 11016.

The key part of the TaSIP gene is the region of its promoter involved in salt tolerance.[TaSIP] (Mus musculus) PubMed

 11017.

Authors show that an m41.1-deficient virus attains reduced titers in salivary glands of wild-type but not Bak1(-/-) mice, indicating a requirement of BAK inhibition for optimal dissemination in vivo.[m41.1] (Mus musculus) PubMed

 11018.

OsCDPK1 activated the expression of a 14-3-3 protein, GF14c.[OsCDPK1, GF14c] (Mus musculus) PubMed

 11019.

vSP-1 interacts with RTA at the protein abundance regulatory signal (PARS) motifs, and the association prevents RTA from being subjected to degradation through the ubiquitin-proteasome pathway.[vSP-1] (Mus musculus) PubMed

 11020.

Branching microtubule nucleation requires gamma-tubulin and augmin and is stimulated by factors previously implicated in chromatin-stimulated nucleation, guanosine triphosphate(GTP)-bound Ran and its effector, TPX2. [augmin] (Mus musculus) PubMed

 11021.

Pbserved is an unusually high thermodynamic and thermal stability of the M69A mutant compared to that of wild-type cytochrome c(552). [cytochrome c(552)] (Mus musculus) PubMed

 11022.

This is the first report that E. coli has a carbapenem-resistance mechanism as a result of PBP2 mutations, and it provides insight into the resistance profiles of PBP2 mutations to carbapenems with and without the 1-beta-methyl group [PBP2; strain MG1655] (Mus musculus) PubMed

 11023.

Using the glnA promoter as model, it was observed that PhoP and GlnR compete for binding to the same promoter region, showing GlnR a higher affinity (PhoP, GlnR and glnA). (Mus musculus) PubMed

 11024.

These data present Rok7B7 as a pleiotropic regulator of growth, carbon catabolite repression, and antibiotic production in Streptomyces [Rok7B7] (Mus musculus) PubMed

 11025.

Candida's glycerol-3-phosphate dehydrogenase 2 (Gpd2) was identified as a novel immune evasion protein that binds factor H, FHL-1 and plasminogen, and human cells. [Gpd2] (Mus musculus) PubMed

 11026.

These studies define a novel role of the cryptococcal Vad1 protein as a central regulator of cryptococcal virulence and illustrate that Vad1 promotes microbe resistance to innate host defenses [Vad1] (Mus musculus) PubMed

 11027.

RIC8 regulates conidial germination through both GNA-1 and GNA-3. [RIC8] (Mus musculus) PubMed

 11028.

Computational modeling of dodecyl maltoside, bilirubin, and protoporphyrin IX into the conserved steroid site shows energetically favorable binding modes for these ligands. [cytochrome C oxidase] (Mus musculus) PubMed

 11029.

Weak expression of PAC1 receptors was detected in non-lactating sheep mammary glands. A significant increase was observed in the lactating sheep samples. PAC1 (Mus musculus) PubMed

 11030.

report herein the NMR structure of Uup 12kDa C-terminal domain, consisting of an intramolecular antiparallel two-stranded coiled coil motif. (Mus musculus) PubMed

 11031.

The molecular changes in the ZmYuc1 gene encoding the YUC1 protein are the causal basis of impairment in a critical step in auxin biosynthesis.[YUCCA1] (Mus musculus) PubMed

 11032.

The crystal structures of 36 monomers of both apo and ligand complexes of PpAOC1 and PpAOC2, are reported.[AOC1, AOC2] (Mus musculus) PubMed

 11033.

These experiments demonstrated direct physical interactions of the IKKepsilon and TBK1 kinases with hepatitis C virus NS2.[NS2] (Mus musculus) PubMed

 11034.

Co-factor binding confers substrate specificity to xylose reductase from Debaryomyces hansenii. [Xylose reductase] (Mus musculus) PubMed

 11035.

The identification and characterization of two CD4+ T cell epitopes of Lpp20 helps understand the protective immunity of Lpp20 in H.pylori infection.[Lpp20] (Mus musculus) PubMed

 11036.

Toxofilin locally upregulates actin turnover thus increasing depolymerization events at the site of entry.[Toxofilin] (Mus musculus) PubMed

 11037.

These results imply that OsABP might perform important functions in the cellular response to specific abiotic stress. [OsABP] (Mus musculus) PubMed

 11038.

Rbfox3-dependent Numb alternative splicing plays an important role in the progression of neuronal differentiation during vertebrate development (Rbfox3). (Mus musculus) PubMed

 11039.

WRKY30 acts as a positive regulator of resistance to fungal diseases, and jasmonic acid signaling plays a significant role in the WRKY30-mediated host resistance to sheath blight and blast fungi in rice.[WRKY30] (Mus musculus) PubMed

 11040.

The self-interaction of Imh1p attenuates the Gcs1p-dependent GTP hydrolysis of Arl1p.[Imh1, Gcs1, Arl1] (Mus musculus) PubMed

 11041.

ROS1a is indispensable in both male and female gametophytes, and DNA demethylation must plays important roles in both gametophytes. [ROS1a] (Mus musculus) PubMed

 11042.

A novel function for the Dwarf3 F-BOX protein in arbuscular mycorrhiza and rice symbiosis (Dwarf3). (Mus musculus) PubMed

 11043.

Authors conclude that ManR is a positive regulator of the beta-mannan utilization system in Aspergillus oryzae.[ManR] (Mus musculus) PubMed

 11044.

These results indicate that the penicillin biosynthesis stimulatory effect of the inducer molecules 1,3-DAP and spermidine is exerted, at least in part, through the stimulation of the expression of laeA.[laeA] (Mus musculus) PubMed

 11045.

study identified a 10-bp DNA sequence that precedes the TATA box of the M112-113 gene, associates with IE3, and is not only essential for IE3 to activate M112-113 gene expression but also is important for MCMV replication [IE3] (Mus musculus) PubMed

 11046.

Ku80 or Lig4 knockdown leads to decreased Agrobacterium-mediated stable transformation and enhanced homologous recombination in rice (Ku80 and Lig4). (Mus musculus) PubMed

 11047.

The results support a model whereby RyhB-1 and RyhB-2 have a global regulatory effect on diverse cellular pathways in response to multiple environmental cues via post-transcriptional regulation of distinct sets of overlapping targets.[RyhB-1 and RyhB-2] (Mus musculus) PubMed

 11048.

type VI effector-immunity complex (Tae4-Tai4) structure provides novel insights into the inhibition mechanism of the effector by its immunity protein [Tae4, Tai4] (Mus musculus) PubMed

 11049.

Specific conserved C-terminal amino acids of Caenorhabditis elegans HMP-1/alpha-catenin modulate F-actin binding independently of vinculin [f-actin, vinculin] (Mus musculus) PubMed

 11050.

study presents the nsp1 structure; it displays a six-stranded beta-barrel fold with a long alpha helix on the rim of the barrel, a fold shared with SARS-CoV nsp1(13-128) [nsp1] (Mus musculus) PubMed

 11051.

Influenza A virus may utilize its NS1 protein to interact with cellular beta-tubulin to further disrupt normal cell division and induce apoptosis.[NS1] (Mus musculus) PubMed

 11052.

Secreted aspartic protease-mediated proteolytic cleavage of Msb2 is required for activation of the Cek1 mitogen activated protein kinase pathway in response to environmental cues.[Msb2] (Mus musculus) PubMed

 11053.

The less than 25% of serum apoB48 in WT mice arises from the intestine, with the majority originating from the liver.(apolipoprotein B48) (Mus musculus) PubMed

 11054.

SPL14 controls tiller growth in rice. [SPL14] (Mus musculus) PubMed

 11055.

RamR represses the ramA promoter by binding to a palindromic sequence. [RamR] (Mus musculus) PubMed

 11056.

The heat stress factor HsfA2 transactivates the promoter of GOLS1 in a heat stress-dependent manner. [HsfA2 and GOLS1] (Mus musculus) PubMed

 11057.

Analysis of Ca2+ signaling motifs that regulate proton signaling through the Na+/H+ exchanger NHX-7 during a rhythmic behavior in Caenorhabditis elegans [NHX7] (Mus musculus) PubMed

 11058.

Details of the catalytic mechanism of Helicobacter pylori octaprenyl pyrophosphate synthase revealed by X-ray crystallography. (Mus musculus) PubMed

 11059.

Determined is the solution structure of HP1264, one of the unusual subunits of Complex I (NADH-quinone oxidoreductase). [HP1264] (Mus musculus) PubMed

 11060.

TLA1 (Truncated light-harvesting antenna 1) is involved in chlorophyll antenna assembly and thylakoid membrane biogenesis.[TLA1] (Mus musculus) PubMed

 11061.

An active role of the MULAN related gene (MRG) product, Mul1b protein, in the activation of the NF-kB pathway during early immune responses. [Mul1b] (Mus musculus) PubMed

 11062.

Our results argue against the predicted involvement of Cys69 and Cys96 on NblR activation by redox sensing. (Mus musculus) PubMed

 11063.

Hcp100 has an important role in the development and maintenance of the H. capsulatum yeast cells within macrophages. Review. Hcp100 (Mus musculus) PubMed

 11064.

heat-labile toxin-subunit B has disulfide bond and O-GlcNAc-1-phosphorylation on serine [heat-liable toxin-subunit B] (Mus musculus) PubMed

 11065.

Analyses of carbohydrate and oil fractions and gene expression profiling on a global scale in the rice waxy mutant GM077 revealed several candidate genes implicated in the carbon reallocation response to an amylose deficiency.[Waxy] (Mus musculus) PubMed

 11066.

This study confirms that rpoS-regulated genes are necessary for persistence during desiccation and osmotic stress conditions. [rpoS] (Mus musculus) PubMed

 11067.

OsSUT1 R188 appears to be essential for sucrose translocation but not for substrate interaction that blocks H+ leak. (sucrose transporter 1) (Mus musculus) PubMed

 11068.

Chitinase isolated from Aspergillus niger LOCK 62 inhibited the growth of the fungal phytopathogens: Fusarium culmorum, Fusarium solani and Rhizoctonia solani. [chitinase] (Mus musculus) PubMed

 11069.

Rhn1, a nuclear protein, is required for suppression of meiotic mRNAs in mitotically dividing fission yeast. [Rhn1 protein] (Mus musculus) PubMed

 11070.

Kinetic studies show that 5-formyltetrahydrofolate (5-FTHF) is a weak inhibitor of thymidylate synthase (TS), suggesting that the TS-5-FTHF complex may function as a source of folates and/or may regulate one-carbon metabolism. [thymidylate synthase ] (Mus musculus) PubMed

 11071.

biological function of lipoprotein 7 is unknown, but its structural homology to sugar-binding proteins suggests that, in analogy to other 30 kDa haemolymph lipoproteins[lipoprotein 7] (Mus musculus) PubMed

 11072.

X-ray crystal structure of the apo cephalosporinase Asn152Gly mutant of P99 was determined to 1.95 A resolution[cephalosporinase] (Mus musculus) PubMed

 11073.

structure of the protein shows high similiarity to the structure of PC4 and it has a similar dimer interface and DNA-binding region to PC4, indicating that MoSub1 could bind DNA using the same motif as other proteins of the Sub1/PC4 family[MoSub1] (Mus musculus) PubMed

 11074.

Two putative aquaporin genes, LjNIP1 and LjXIP1, which resulted to be upregulated in a transcriptomic analysis performed on mycorrhizal roots of Lotus japonicus, are reported.[LjNIP1, LjXIP1] (Mus musculus) PubMed

 11075.

The results demonstrated that the AiiA quorum-sensing system negatively regulates proteolytic activity and is likely involved in the early steps of biofilm formation by E. cloacae 067. [AiiA] (Mus musculus) PubMed

 11076.

Placenta sections revealed specific expression Syncytin-Rum1 in the trophoblast binucleate cells, consistent with a role in the formation--by heterologous cell fusion with uterine cells.[Syncytin-Rum1] (Mus musculus) PubMed

 11077.

These findings establish PLP2 deubiquitinating enzyme activity as a critical factor in arteriviral innate immune evasion.[PALP2] (Mus musculus) PubMed

 11078.

the discovery that three coiled-coil proteins-Rec25, Rec27, and Mug20-bind essentially all hot spots with great specificity even without DSB formation( Rec25, Rec27, and Mug20) (Mus musculus) PubMed

 11079.

Adenosine exerts a powerful negative feedback control of ATP release from the urothelium via A1 receptor activation [adenosine A1 receptor] (Mus musculus) PubMed

 11080.

A consensus motif with a 5-bp imperfect palindromic sequence [ATTCC-N(7(5))-GGAAT] was identified among all four GenR binding sites and found to be necessary to GenR regulation through site-directed mutagenesis.[GenR] (Mus musculus) PubMed

 11081.

Characterization of Anopheles gambiae transglutaminase 3 (AgTG3) and its native substrate Plugin (Mus musculus) PubMed

 11082.

Results from epistasis assays and genetic complementation analyses suggest that Rbf upregulates SarX, which then downregulates IcaR, thereby activating icaADBC.[Rbf, SarX] (Mus musculus) PubMed

 11083.

Results indicate that rice proteins JMJ703 is an active H3K4-specific demethylase required for transposable elements (TEs) silencing: [JMJ703] (Mus musculus) PubMed

 11084.

PHYSCODILLO proteins have novel and pleiotropic functions, some of which may be conserved in later-evolving plants [PHYSCODILLO1A, PHYSCODILLO-1B, PHYSCODILLO2] (Mus musculus) PubMed

 11085.

These data suggest a close interplay of HrrSA and ChrSA at the level of transcription and emphasize ChrSA as a second two-component system involved in haem-dependent gene regulation in Corynebacterium glutamicum.[ChrS, ChrA] (Mus musculus) PubMed

 11086.

Results suggested that BmTGIF interacted with BmAly, and that they may recruit other factors to form a complex to regulate the genes required for meiotic divisions and spermatid differentiation (BmTGIF). (Mus musculus) PubMed

 11087.

The aim of this study was to screen the inhibitory potential of several testicular steroids on cytochrome P450 3A (CYP3A) and 2C (CYP2C) activities in porcine liver microsomes.[cyp3a; cyp2c] (Mus musculus) PubMed

 11088.

MicA is able to self associate in the presence of magnesium to form oligomers. (Mus musculus) PubMed

 11089.

Duts are widespread cellular regulators acting in a manner analogous to the eukaryotic G proteins.(Duts) (Mus musculus) PubMed

 11090.

The glycine content in the cell walls of whole cells was increased by approximately 30% for the FemA mutant and was reduced by 25% for the FemB mutant relative to expected values for homogeneous structures.[FemB] (Mus musculus) PubMed

 11091.

structure of an elongation complex in which the tip complex assembly composed of FimC, FimF, FimG and FimH passes through FimD [FimD] (Mus musculus) PubMed

 11092.

ankyrin repeats domain 17 was identified as a host factor that could interact with IE3 (Mus musculus) PubMed

 11093.

The frequency of molecular markers of P. falciparum resistance/tolerance via the chloroquine resistance transporter (CRT) and multidrug resistance gene-1 (MDR1) are reported.[CRT; MDR1] (Mus musculus) PubMed

 11094.

cCF10 gene expression was increased in clinical strain formed biofilm isolates from renal transplant patients. [cCF10] (Mus musculus) PubMed

 11095.

OsNAC5 played an important role in the tolerance of rice plants to abiotic stress by regulating downstream targets associated with accumulation of compatible solutes, Na(+) ions, H(2)O(2) and malondialdehyde. [OsNAC5] (Mus musculus) PubMed

 11096.

B-cell epitopes in the DBL4epsilon domain of VAR2CSA, were identified.[VAR2CSA] (Mus musculus) PubMed

 11097.

DNA microarray and transcriptional reporter analyses with a rokA mutant revealed that RokA acts as a transcriptional repressor of the SPD0424-8 operon.[RokA] (Mus musculus) PubMed

 11098.

analysis of the catalytic proton network of the Toho-1 beta-lactamase for the acylation reaction [toho-1] (Mus musculus) PubMed

 11099.

The Zmf3'h1 gene participates in the biosynthesis of phlobaphenes and agronomically important 3-deoxyflavonoid compounds under the regulatory control of P1.[P1, ZmF3'H1] (Mus musculus) PubMed

 11100.

A GH3 family gene, OsGH3-2, encoding an enzyme catalysing indole-3-acetic acid conjugation to amino acids, is involved in the modulation of abscisic acid (ABA) level and stress tolerance in rice. [OsGH3-2 protein] (Mus musculus) PubMed

 11101.

VvNPR1.1 played an important role in grapevine defense against biotrophic pathogens (VvNPR1.1). (Mus musculus) PubMed

 11102.

Data indicate that cysteine (Cys8) is required for the Pex20 mono- and diubiquitination and recycling: [Pex20] (Mus musculus) PubMed

 11103.

Both conventional and accelerated molecular dynamics simulations of S. aureus SrtA in its apo state and when bound to an LPATG sorting signal (SS) were performed. [SrtA] (Mus musculus) PubMed

 11104.

PNGase is a functional peptide:N-glycanase enzyme possessing deglycosylation activity, but does not possess any significant transamidation activity.(PNGase A) (Mus musculus) PubMed

 11105.

The NMR structure of the calflagin Tb24 flagellar calcium binding protein contains four EF-hand motifs bundled in a compact arrangement. [Tb24] (Mus musculus) PubMed

 11106.

Data suggest that aquaporin-1 (AaAQP1b) and aquaporin-4 (AaAQP4) are expressed in anal papillae of laboratory-raised larva; these aquaporins appear to be involved in water transport across the anal papillae. [AaAQP4; aquaporin-4] (Mus musculus) PubMed

 11107.

new insights into the biological function of the staphylococcal Gcp [Gcp] (Mus musculus) PubMed

 11108.

a novel mode of p97 interaction with the core autophagy protein ATG9 which is based on mutual inhibition [p97][ATG9] (Mus musculus) PubMed

 11109.

oligonucleotide binding (OB)-fold domain of KREPA4 is essential for stable incorporation into editosomes [KREPA4] (Mus musculus) PubMed

 11110.

Thanatos-associated protein (THAP) and activating transcription factor-2 (ATF-2), antagonistically control AeSCP-2 transcriptional activity in the midgut of feeding larvae [THAP][ATF-2][SCP-2] (Mus musculus) PubMed

 11111.

The mode of C. elegans gastrulation can be unified with the general notions of monolayer remodeling and with distinct cellular mechanisms of actomyosin-based morphogenesis.[Actomyosin] (Mus musculus) PubMed

 11112.

The crystal structure of the uridine phosphorylase of Vibrio cholerae in complex with thymidine. [VchUPh] (Mus musculus) PubMed

 11113.

In agreement with the theoretical predictions, no pyruvate decarboxylase activity was detected for recombinant fermentation-respiration switch (FrsA) protein that could be crystallized and structurally characterized.[FrsA] (Mus musculus) PubMed

 11114.

A likely function for RutC is the reduction of peroxy-aminoacrylate to aminoacrylate as a part of a detoxification process. [RutC] (Mus musculus) PubMed

 11115.

work demonstrates a stage-specific essentiality of the unique PPKL enzyme, which modulates parasite differentiation, motility and transmission [PPKL] (Mus musculus) PubMed

 11116.

The study analysed the mechanism and specificity of an acyltransferase domain from module 3 of the 6-deoxyerythronolide B synthase. [6-deoxyerythronolide B synthase] (Mus musculus) PubMed

 11117.

VelB acts as a positive regulator of asexual development and regulates spore maturation, focal trehalose biogenesis and germination by interacting with VosA in A. nidulans [VelB, VosA] (Mus musculus) PubMed

 11118.

Oligomerization of ZWF1 protein (glucose 6-phosphate dehydrogenase) is regulated by cytosolic NADPH level. (Mus musculus) PubMed

 11119.

Msl1 plays role in thermotolerance, virulence, sexual differentiation and melanin production. (Mus musculus) PubMed

 11120.

Myb3 nuclear localization signal localizes to 180 C-terminal amino acids. (Mus musculus) PubMed

 11121.

homeobox BcHOX8 gene in Botrytis cinerea regulates vegetative growth and morphology [BcHOX8] (Mus musculus) PubMed

 11122.

CrLIP1 facilitates triacylglycerol turnover by degrading diacylglycerols generated from triacylglycerol hydrolysis. (Mus musculus) PubMed

 11123.

4E-BP plays a central role under hypoxia in promoting the cap-independent translation.[4E-BP] (Mus musculus) PubMed

 11124.

In solution, the DnaT protein exists as a monomer-trimer equilibrium system. The oligomerization reaction is a highly specific and cooperative process. [DnaT] (Mus musculus) PubMed

 11125.

Binding of Mg(2+) cations dramatically changes the thermodynamic functions of the DnaT trimerization, transforming the reaction from a temperature-dependent to temperature-independent process. [DnaT] (Mus musculus) PubMed

 11126.

The up-regulation of VRN1 during winter is required to maintain low transcript levels of VRN2, accelerate the induction of FT in the leaves, and regulate a timely flowering in the spring (Mus musculus) PubMed

 11127.

Data indicate that pseudoperoxidase (LmPP)V90H has lower catalytic activity compared to the wild type enzyme: [LmPP] (Mus musculus) PubMed

 11128.

These data indicate that the M1 protein is an important determinant of viral replication and pathogenic properties in mice, although the functions of M1 observed in vivo are not adequately reflected in simple infections of cultured cells.[M1] (Mus musculus) PubMed

 11129.

Site-specific mutations at the five putative active sites in the PR-1 domain all affected dimerization, with the mutations at Glu-72 and Glu-102 (in the PR-1-5 numeration) also diminishing protease resistance. [PR-1-5] (Mus musculus) PubMed

 11130.

The prevalence of agr dysfunction, reduced vancomycin susceptibility and the outcomes of SCCmec IV/IVa and I-III methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, were compared. (Mus musculus) PubMed

 11131.

The osmosensor Sho1p is required for correct cell-cell separation.[Sho1p] (Mus musculus) PubMed

 11132.

TbKIN-D cooperates with TbKIN-C to maintain cell morphology by regulating the organization of the subpellicular microtubule corset.[TbKIN-C, TbKIN-D] (Mus musculus) PubMed

 11133.

DDF1 is a crucial genetic factor with pleiotropic functions for both vegetative growth and floral organ specification in rice. [DDF1] (Mus musculus) PubMed

 11134.

Transition state of immunodeficiency virus glycoprotein 41 exhibits compact native lake structure. Folding of the wild-type as well as most mutants can be described with simple monomer-trimer folding reaction mechanism. [SIV gp41] (Mus musculus) PubMed

 11135.

Both heme oxygenase (HO) and Ca2+ are required for methyl jasmonate (MJ)-induced Lateral root formation in rice. [OsHO1] (Mus musculus) PubMed

 11136.

A single side-chain mutation in the active site strongly reduced the rate of substrate turnover and changed the conformational dynamics of all amino acids involved in catalysis. [SlyD] (Mus musculus) PubMed

 11137.

The cryptococcal transcript for the extracellular mannoprotein Cig1 is highly regulated by iron and abundant in iron-starved cells, suggesting a role in iron acquisition. [Cig1] (Mus musculus) PubMed

 11138.

A specific induction of Aox1 gene expression in roots of the tolerant genotype that presented the lowest modulation in phenotypic and biochemical stress indices such as morphologic changes, protein level, lipid peroxidation and ROS generation. (Mus musculus) PubMed

 11139.

During development of soybean meal diet induced enteritis, reductions of all three fabp2 (fatty acid binding protein) isoforms were noticed in the intestine. [fabp2] (Mus musculus) PubMed

 11140.

Fps1 Fps2 double mutant (lacking both glycerol channels) accumulates glycerol, is hypersensitive to osmotic stress and caspofungin. (Mus musculus) PubMed

 11141.

Pes1 protein (pescadillo homolog) is essential for Candida albicans virulence in animal disease models. (Mus musculus) PubMed

 11142.

TamiR159 directs wheat TaGAMYB cleavage and its involvement in anther development and heat response [GAMYB] (Mus musculus) PubMed

 11143.

Deletion of PcpA encoding pericentrin-related protein affects cell polarity and microtubule organization. (Mus musculus) PubMed

 11144.

Urotensin II (UII)plays a role in satiety and/or aversive signaling in feeding behaviors in Aplysia. (Mus musculus) PubMed

 11145.

comprehensive characterization of the SS2 enolase octamer [enolase] (Mus musculus) PubMed

 11146.

FhuA DeltaC/Delta4L features an approximate conical internal geometry with the cis entrance smaller than the trans entrance, in accord with the asymmetric nature of the crystal structure of the wild-type FhuA protein.[FhuA] (Mus musculus) PubMed

 11147.

Cold and heat unfolding of Pfk-2 resembles the N(2)<-->2I step of chemically induced unfolding.[Pfk-2] (Mus musculus) PubMed

 11148.

An internal signaling pathway that spans from the nucleotide-binding site to an ~2.3-nm-distant region in the HtpG middle domain, was identified.[HtpG] (Mus musculus) PubMed

 11149.

GL3.1 directly dephosphorylates its substrate, Cyclin-T1;3, which has only been rarely studied in plants. (GL3.1 protein) (Mus musculus) PubMed

 11150.

NSP1, when combined with NSP2, can act as a strong positive regulator of ERN1 and ENOD11 transcription.[ERN1, NSP1, NSP2, ENOD11] (Mus musculus) PubMed

 11151.

the proteins ROP2 and ROP4 from the rhoptry, GRA2 from the dense granules and the surface protein SAG1 were found to bind heparin (ROP2, ROP4, GRA2, SAG1) (Mus musculus) PubMed

 11152.

Authors identified CacA as an activator of the CpxR/CpxA system in the plasmid clone.[CacA] (Mus musculus) PubMed

 11153.

Knockdown expression of OsNRT2.3a by RNA interference (RNAi) had impaired xylem loading of nitrate and decreased plant growth at low (0.5 mm) nitrate supply.[OsNRT2.3a] (Mus musculus) PubMed

 11154.

Lytic activity of the Vibrio cholerae type VI secretion toxin VgrG-3 is inhibited by the antitoxin TsaB [TsaB, VgrG-3, strain V52] (Mus musculus) PubMed

 11155.

Restriction of influenza A virus replication was accounted for by the interaction between TRIM22 and the viral nucleoprotein (NP), resulting in its polyubiquitination and degradation in a proteasome-dependent manner (Mus musculus) PubMed

 11156.

A positive reaction was found between Arabidopsis thaliana SCE1 protein and NIb, the Turnip mosaic virus RNA-dependent RNA polymerase.[NIb] (Mus musculus) PubMed

 11157.

These results indicate that efficient Dengue virus RNA replication requires only minimal, if any, nuclear NS5, and they identify the alphabeta nuclear localization signal as a structural element required for proper RNA-dependent RNA polymerase activity.[NS5] (Mus musculus) PubMed

 11158.

PfUvrD is expressed in the nucleus distinctly in the schizont stages of the intraerythrocytic development of the parasite and it colocalizes with PfMLH.[PfMLH] (Mus musculus) PubMed

 11159.

Authors demonstrate that smpB is regulated by RNase R and RNase R in turn, is shown to be under the control of SmpB.[RNase R] (Mus musculus) PubMed

 11160.

Ghd7 is an important rice gene that has a major effect on several agronomic traits, including yield. The Ghd7 regions have low gene densities and high contents of repetitive elements. [Ghd7] (Mus musculus) PubMed

 11161.

The present study describes Pf332 as a resident peripheral membrane protein of Maurer's clefts.[Pf332] (Mus musculus) PubMed

 11162.

Taken together, these findings indicate that RegR controls the expression of a series of accessory adhesins that significantly enhance the virulence of REPEC strain E22.[RegR] (Mus musculus) PubMed

 11163.

Paracoccidioides brasiliensis Amy1 produces maltooligosaccharides which may act as a primer molecule for the fungal cell wall alpha-(1,3)-glucan biosynthesis.[Amy1] (Mus musculus) PubMed

 11164.

Crystallization and preliminary X-ray crystallographic analysis of quinolinate phosphoribosyltransferase from porcine kidney in complex with nicotinate mononucleotide. (QAPRTase) (Mus musculus) PubMed

 11165.

The H-1PV structure has been determined by molecular replacement and is currently being refined. (Mus musculus) PubMed

 11166.

phosphorylation of the N-terminal domain of the cucumber mosaic virus polymerase 2a protein [polymerase 2a[ (Mus musculus) PubMed

 11167.

EhCaBP5 was cloned, expressed in Escherichia coli and purified using affinity and size-exclusion chromatography.(EhCaBP5) (Mus musculus) PubMed

 11168.

Both steC-null and kinase-deficient mutant strains displayed enhanced replication in infected cells, suggesting that SteC manipulates the actin cytoskeleton to restrain bacterial growth, thereby regulating virulence. [SteC] (Mus musculus) PubMed

 11169.

The Mg277 ORF product was overexpressed in Escherichia coli, purified and crystallized (Mg277) (Mus musculus) PubMed

 11170.

in the chick embryo, AP2gamma acts downstream of the BMP pathway to restrict precocious neural expansion in the prospective neural plate and initiates epidermal differentiation in the future epidermal ectoderm [AP2gamma] (Mus musculus) PubMed

 11171.

Mechanism for induction of the sigmaF-dependent genes by chromium and cadmium is the inactivation of the putative anti-sigma factor NrsF, leading to the release of sigmaF to bind RNA polymerase core and drive transcription of its regulon.[NrsF, Sigma factor F] (Mus musculus) PubMed

 11172.

Localization of substance P, in the nerve fibers of porcine cystic ovaries. [substance P] (Mus musculus) PubMed

 11173.

serum markers were estimated and resulted in a positive correlation of neuro specific enolase with lesion volume in traumatic brain injury--on-specific enolase {new entry} (Mus musculus) PubMed

 11174.

Ciona intestinalis myogenic regulatory factor studies reveal conserved features of chordate myogenesis [Ci-MRF] (Mus musculus) PubMed

 11175.

(NCA localization factor-1 (NLF-1)) An endoplasmic reticulum protein, NLF-1, delivers a sodium leak channel critical for rhythmic locomotion. (Mus musculus) PubMed

 11176.

Two microRNAs, miR171, miR397, specifically responding to symbiotic infection and nodule function in legumes, were identified.[miR171, miR397] (Mus musculus) PubMed

 11177.

SET1 is required for DNA methylation in the frq promoter, indicating a dependence on H3K4me for DNA methylation. [SET1] (Mus musculus) PubMed

 11178.

SUB1A genotypes displayed altered responses to prolonged darkness by limiting ethylene production and responsiveness to jasmonate and salicylic acid.[SUB1A] (Mus musculus) PubMed

 11179.

A dual mode of membrane association may promote PLP1 activity and parasite egress in the diverse cell types in which this parasite replicates. [PLP1] (Mus musculus) PubMed

 11180.

Hsp90 plays an important role as a molecular chaperone in CB2 receptor-mediated cell signaling and actin cytoskeleton rearrangement in trabecular meshwork cells. [CB2 receptor] (Mus musculus) PubMed

 11181.

The study investigates the interactions between the E43S-mutant Staphylococcal nuclease ([E43S]SNase) and ssDNA in the presence of Cd(2+) using various NMR techniques. [Staphylococcal nuclease] (Mus musculus) PubMed

 11182.

crystal structure; and CupA is a previously uncharacterized cell membrane-anchored Cu(I) chaperone and a Cu(I) binding-competent, membrane-localized CupA is obligatory for copper resistance (Mus musculus) PubMed

 11183.

Inositol trisphosphate content was reduced in the CnDeltaplc1 mutant and markedly increased in the CnDeltaarg1 mutant, while phosphatidylinositol 4,5-bisphosphate was increased in both mutants.[plc1, arg1] (Mus musculus) PubMed

 11184.

These results indicate that Slr1 is an SR-like protein that influences Candida albicans growth, filamentation, host cell interactions, and virulence.[Slr1] (Mus musculus) PubMed

 11185.

Cyclophilin (Cyp19) serves as a molecular sensor leading to the evasion and adaptive metabolic response to insect defense peptides. [Cyp19] (Mus musculus) PubMed

 11186.

OSTA-1 as a crucial regulator of ciliary architecture via regulation of cilia-destined trafficking. [Osta-1 protein, C.elegans] (Mus musculus) PubMed

 11187.

the gene duplication and diversification of tandem cellulase genes in thermophilic bacteria [cel5C][cel5D] (Mus musculus) PubMed

 11188.

D2-like receptor signaling also attenuates the excitability of additional mating circuits to reduce the duration of mating attempts with unproductive and/or inappropriate partners. (Mus musculus) PubMed

 11189.

Authors also demonstrate that VPg, P0, and eIF(iso)4E synergistically enhance viral translation.[VPg] (Mus musculus) PubMed

 11190.

LT-IIc, a newly discovered E. coli LT, is comprised of an A polypeptide with high homology, and a B polypeptide with moderate homology, to LT-IIa and LT-IIb. (LT-IIc) (Mus musculus) PubMed

 11191.

ASR5 might be sequestered in the chloroplasts as an inactive transcription factor that could be released to the nucleus in response to Aluminum to regulate genes related to photosynthesis.[ASR5] (Mus musculus) PubMed

 11192.

Increases in methylglyoxal (MG) leads to the increase in TPI.[TPI] (Mus musculus) PubMed

 11193.

Caenorhabditis elegans elegans p38 mitogen-activated protein kinase (MAPK) pathway is activated in the regulation of host susceptibility to Enterohaemorrhagic Escherichia coli O157:H7 infection in a Stx1-dependent manner.[p38 MAPK] (Mus musculus) PubMed

 11194.

Caenorhabditis elegans elegans p38 mitogen-activated protein kinase (MAPK) pathway is activated in the regulation of host susceptibility to Enterohaemorrhagic Escherichia coli O157:H7 infection in a Stx1-dependent manner.[Stx1] (Mus musculus) PubMed

 11195.

Authors show that nitric oxide and haemin, two inducers of HO-1, decrease the level of phosphorylated CagA in Helicobacter pylori-infected gastric epithelial cells.[CagA] (Mus musculus) PubMed

 11196.

This study presents the preparation, biophysical characterization, and nuclear magnetic resonance spectroscopy characterization of yeast cytochrome c peroxidase constructs with enhanced solubility. [cytochrome c peroxidase] (Mus musculus) PubMed

 11197.

miR-K12-11, microRNA155 homolog encoded by Kaposi sarcoma-associated herpesvirus promotes B-cell expansion in vivo [miR-K11-12] (Mus musculus) PubMed

 11198.

The interaction of LepR3 with the L. maculans avirulence gene AvrLm1, was investigated.[AVRLM1] (Mus musculus) PubMed

 11199.

miR-135b expression during cigarette smoke-induced inflammation is regulated by IL-1R1 in a regulatory feedback mechanism to resolve inflammation. (Mus musculus) PubMed

 11200.

These data point to a role for Topo III in chromosome segregation when gyrB is inefficient and suggest that Topo I plays an indirect role via supercoiling regulation.[gyrB] (Mus musculus) PubMed

 11201.

These results suggest that Esp inhibits S. aureus colonization and biofilm formation by degrading specific proteins that are crucial for biofilm construction and host-pathogen interaction [Esp][strain JK16] (Mus musculus) PubMed

 11202.

HIPP41 gene is highly expressed in response to cold and drought stresses, and its product is localized in the cytosol and the nucleus. [HIPP41] (Mus musculus) PubMed

 11203.

These findings on TgAlba1 and TgAlba2 are consistent with a role in gene-specific translation.[Alba1, Alba2] (Mus musculus) PubMed

 11204.

These computational findings suggest the existence of new reaction intermediates following the proton abstraction catalyzed by thymidylate synthase.[thymidylate synthase] (Mus musculus) PubMed

 11205.

Ten Hfq-regulated sRNAs were identified using a computational method, and two of these sRNAs, RprA and RyhA, were found to be required for the full virulence of E. amylovora[Hfq] (Mus musculus) PubMed

 11206.

We identify three new murein hydrolytic enzymes in Escherichia coli, two (Spr and YdhO) in the NlpC/P60 peptidase superfamily and the third (YebA) in the lysostaphin family that cleave peptide cross-bridges between glycan chains. [Spr, YdhO, YebA] (Mus musculus) PubMed

 11207.

Results inferred that bmo-miR-1a-3p may downregulate BmVMP23 expression via complementary interaction with the target sites at the 3' UTR:[bmo-miR-1a-3p and BmVMP23] (Mus musculus) PubMed

 11208.

These data suggest that Nicotiana benthamiana eEF1B may be a component of the Tobacco mosaic virus replication complex which interacts with MT domain of Tobacco mosaic virus RNA-dependent RNA polymerase and eEF1A.[RNA-dependent RNA polymerase] (Mus musculus) PubMed

 11209.

Authors provide evidence that the Escherichia coli Cytolethal Distending Toxin (CDT) - at low dose (50 pg ml(-1) or LD50) and early after treatment (3-6 h) - progressively induces DNA double-strand breaks, mostly in S-phase.[CDT] (Mus musculus) PubMed

 11210.

When V. cholerae reaches high density on chitin, CytR-CRP interactions 'anti-activate' multiple genes, including a possible factor that negatively controls DNA uptake. [CytR, CRP] (Mus musculus) PubMed

 11211.

We present an atomic resolution model for the crystal structure of CS6 and suggest CS6-mediated adhesion is due to CssA and CssB subunits assembled alternately in linear fibres via donor strand complementation. [CS6] (Mus musculus) PubMed

 11212.

Computer docking suggested that highly accelerated monophosphoimidazole autophosphorylation rates for CheY variants with a tyrosine at position T + 2 likely reflect structural mimicry of phosphotransfer from the sensor kinase histidyl phosphate. [CheY] (Mus musculus) PubMed

 11213.

MacA-dependent stimulation of MacB ATPase is coupled to recruitment of TolC channel. [MacA, MacB, TolC] (Mus musculus) PubMed

 11214.

OsRab11 is essential for the vesicle trafficking of the vacuolar H(+)-ATPase OsVHA-a1 under high salinity conditions in rice. (Mus musculus) PubMed

 11215.

OsGAP1 and OsRab11 are essential for the vesicle trafficking of OsVHA-a1 to the PVC and/or the central vacuole under high salinity. [OsGAP1] (Mus musculus) PubMed

 11216.

These data showed that the Ile-141/Td-3 interaction was important for the strand transfer activity and the oligomerization of integrase.[integrase] (Mus musculus) PubMed

 11217.

role of ataxin-7 in differentiation of photoreceptors and cerebellar neurons (Mus musculus) PubMed

 11218.

These findings provide a molecular link between Helicobacter pylori and gastric carcinogenesis through the specific accumulation of CagA in gastric cancer stem-like cells.[CagA] (Mus musculus) PubMed

 11219.

mutations that affect components of the eIF4F-complex loose properties such as adhesion and pseudohyphal differentiation (Mus musculus) PubMed

 11220.

In either the presence or the absence of RppH, arresting translation elongation appears to hinder RNase E cleavage within the coding region but not within the 5' UTR upstream of the ribosome binding site. [RppH, RnaseE] (Mus musculus) PubMed

 11221.

The maturation of replicating Deltap52&p36 parasites in cultured Huh-7 hepatocytes, were studied.[p52, p36] (Mus musculus) PubMed

 11222.

The SD3 loop of PfEMP1-DBL1alpha is an important target of anti-rosetting activity, clarifying the molecular basis of the development of variant-specific rosette disrupting antibodies.[PfEMP1] (Mus musculus) PubMed

 11223.

Parasites selected for in vivo PfRh4 activation show a reversible increase in promoter accessibility and exhibit perinuclear repositioning of the locus from a silent to a conserved activation domain.[PfRh4] (Mus musculus) PubMed

 11224.

DRBD3 transports regulated mRNAs within the cell in the form of ribonucleoprotein complexes that are remodeled in response to environmental cues. [DRBD3] (Mus musculus) PubMed

 11225.

The RtxA1 toxin caused an increase in the intracellular Ca(2+) concentration and the subsequent activation of JNK.[RtxA1] (Mus musculus) PubMed

 11226.

HP0197 could enhance CcpA activity to control the expression of genes involved in carbohydrate utilization and capsular polysaccharides synthesis, thus contributing to the virulence of S. suis.[HP0197, CcpA] (Mus musculus) PubMed

 11227.

ATP is dispensable for and does not interfere with Hfq-mediated RNA transactions.[Hfq] (Mus musculus) PubMed

 11228.

NMR solution structure for CBM11 supports a selection mechanism where a rigid protein selects a defined oligosaccharide conformation [CBM11] (Mus musculus) PubMed

 11229.

Importantly, acl1 mutants were unable to cause disease in a murine inhalation model, a phenotype that was more extreme than other mutants with defects in acetyl-CoA production (e.g. an acetyl-CoA synthetase mutant).[acl1] (Mus musculus) PubMed

 11230.

We found that loss of the enzyme (JMJ703) reduces cell division rate of the stem and the size of plant stature, indicating the importance of the protein in plant growth (Mus musculus) PubMed

 11231.

These results indicate that Cc.Snf5 plays an essential role in sexual development of Coprinopsis cinerea cinerea.[Snf5] (Mus musculus) PubMed

 11232.

we demonstrate that mutation of the Scd5 PP1 binding site leads to major delays in coat development and progression to the mobile actin phase of internalization (Mus musculus) PubMed

 11233.

Results of this study indicate that BcVeA and BcVelB coordinate similar processes in the regulation of fungal development, oxidative stress response, and virulence in B. cinerea.[VEA, VELB] (Mus musculus) PubMed

 11234.

Our findings demonstrate that HelP is a helicase processivity factor needed for efficient unwinding of ICEBs1 for conjugation and replication (Mus musculus) PubMed

 11235.

ORF YML081W therefore encodes a transcription factor that regulates acetate production in Saccharomyces cerevisiae. We propose AAF1 as a gene name for the YML081W ORF. (Mus musculus) PubMed

 11236.

A striking difference between PaGH61A and PaGH61B was observed through the identification of the products, among which were doubly and triply oxidized cellodextrins.[GH61A, GH61B] (Mus musculus) PubMed

 11237.

Opy2 is required to trigger Cek1 phosphorylation by different stimuli such as the resumption of growth from stationary phase.[Opy2] (Mus musculus) PubMed

 11238.

SPy1599 contains a phosphate-binding pocket in the active site, has putative 6-phospho-beta-glycosidase activity; kinetic analysis shows that SPy1599 has 6-phospho-beta-glucosidase activity and is involved in intracellular degradation of 6-phosphoglycosides. (Mus musculus) PubMed

 11239.

The study reports the identification of a novel L-xylulose reductase LXR3 in the fungus Trichoderma reesei by a bioinformatic approach in combination with a functional analysis.[LXR3] (Mus musculus) PubMed

 11240.

loss-of-function mutation in WNK1 induces an overexpression of KCC2 and hinders proper peripheral sensory nerve development, a hallmark of HSANII (Mus musculus) PubMed

 11241.

Mitochondrial beta-oxidation primarily contributes to conidial viability and maintenance of redox homeostasis during host colonization by Magnaporthe.[ech1] (Mus musculus) PubMed

 11242.

Rice Os9BGlu31 is a transglucosidase with the capacity to equilibrate phenylpropanoid, flavonoid, and phytohormone glycoconjugates [Os9BGlu31] (Mus musculus) PubMed

 11243.

The predominant species of the cyanobacterial metalloregulatory protein SmtB as observed by ESI-MS is a dimer with all four zinc binding sites occupied.[SmtB] (Mus musculus) PubMed

 11244.

Authors show that NP self-associates much more weakly in the absence of RNA than in its presence, indicating that oligomerization is very limited in the cytoplasm.[NP] (Mus musculus) PubMed

 11245.

Motility assays and time-lapse video microscopy showed that pneumococcal stimulation of macrophage motility required RrgA and complement receptor 3.[RrgA] (Mus musculus) PubMed

 11246.

A mutation in YlPEX5, which encode a peroxisomal targeting signal receptor, partially suppressed the defective hyphal growth of Yllac1Delta.[YlPEX5, Yllac1] (Mus musculus) PubMed

 11247.

Cch1 and Mid1 activity are important in morphogenesis, oxidative stress response and virulence.[Cch1, Mid1] (Mus musculus) PubMed

 11248.

Rapid X-ray photoreduction of dimetal-oxygen cofactors in ribonucleotide reductase [ribonucleotide reductase] (Mus musculus) PubMed

 11249.

Evidence of carbon monoxide binding at the active site of Escherichia coli cytochrome bd terminal oxidase. [cytochrome bd terminal oxidase] (Mus musculus) PubMed

 11250.

Here we describe an additional novel function for budding yeast Pol eta, i.e. formation of postreplicative DI genome-wide cohesion. (Mus musculus) PubMed

 11251.

Taken together, these findings suggest that only the N-terminal region of FlhA is needed for transcription of the RpoN regulon.[FlhA, RpoN] (Mus musculus) PubMed

 11252.

GlxR binding sites were identified in the sequence of 79 enriched DNA fragments, of which 21 sites were not previously reported.[GlxR] (Mus musculus) PubMed

 11253.

these results suggest that MedA functions in the regulation of transcription, and that the MedA(346-557) domain is both necessary and sufficient to mediate MedA function. (Mus musculus) PubMed

 11254.

crystal structure of the transmissible-mutant H5 HA in complex with receptor analogues shows that it has acquired the ability to bind human receptor in the same folded-back conformation as seen for HA from the 1918, 1957, 1968 and 2009 pandemic viruses (Mus musculus) PubMed

 11255.

the Cch1-Mid1 channel complex is a calcium selective store-operated channel that is gated by the depletion of intracellular calcium. [Mid1] (Mus musculus) PubMed

 11256.

The effect of L. lactis subsp. cremoris on interferon-gamma expression in NK and T cells via the IL-12 and IL-18 pathway is described.[IL-12] (Mus musculus) PubMed

 11257.

study has identified OsbHLH133 as a regulator of Fe homeostasis in rice, most likely by negatively regulating Fe transportation from root to shoot[bHLH133] (Mus musculus) PubMed

 11258.

phenolase activity (phenol hydroxylation) of the activated tyrosinase involves an electrophilic aromatic substitution mechanism [melB] (Mus musculus) PubMed

 11259.

the integrated and balanced regulation of TORC1 and TORC2 might be crucial in Dictyostelium to coordinate growth and energy needs with other essential TOR-regulated processes [TORC1 & TORC2] (Mus musculus) PubMed

 11260.

Net2 is a new locus on the short arm of chromosome 2D that induces Dobzhansky-Muller (DM)-type hybrid incompatibility in wheat. [net2] (Mus musculus) PubMed

 11261.

Report highly sensitive ELISA for the detection of Staphylococcus aureus alpha hemolysin. (Mus musculus) PubMed

 11262.

Clarification of glycosylation and protein trafficking of TbPDI2, a trypanosomal protein disulfide isomerase orthologue specifically upregulated in pathogenic bloodstream-form. (Mus musculus) PubMed

 11263.

A role for the MAK-1 pathway as an output pathway of the circadian clock in Neurospora crassa. [MAK-1] (Mus musculus) PubMed

 11264.

OsMADS29 has important functions in seed development of rice by regulating cell degeneration of maternal tissues.[OsMADS29] (Mus musculus) PubMed

 11265.

C-terminal domain of HIV-1 capsid protein as surrogate for human lysyl tRNA synthetase [LysU] (Mus musculus) PubMed

 11266.

N-terminal tetra-peptide extension of the U-box participates in the specific interaction of SPL11 E3 ligase with E2s ligases in a sequence-specific manner(SPL11 E3 ligase). (Mus musculus) PubMed

 11267.

characterization of FAAH and identify NAEs in D. discoideum (Mus musculus) PubMed

 11268.

Pkh2-0 mediated signaling in C. neoformans is crucial for stress tolerance, host-pathogen interactions, and both temperature-dependent and -independent virulence. [Pkh2-02] (Mus musculus) PubMed

 11269.

The data suggest that two rice long-chain base kinase (LCBK) genes,(OsLCBK1 and OsLCBK2), play important roles in disease resistance response and programmed cell death in plants (OsLCBK1 and OsLCBK2). (Mus musculus) PubMed

 11270.

study cloned, expressed, and characterized a pseudoperoxidase (LmPP) that is capable of detoxifying peroxynitrite (ONOO(-)); data provide strong evidence that LmPP plays an important role in the enzymatic defense against ONOO(-) within macrophages [pseudoperoxidase] (Mus musculus) PubMed

 11271.

Blood vessels generated via angiogenesis are affected in invadolysin morphant fish while those formed by vasculogenesis appear normal, demonstrating an unanticipated role for invadolysin in vessel formation. [Invadolysin, Danio rerio] (Mus musculus) PubMed

 11272.

SdrF is a multifunctional protein that contributes to prosthetic devices infections by ionic, as well as specific receptor-ligand interactions. [SdrF] (Mus musculus) PubMed

 11273.

Novel aminoglycoside 2''-phosphotransferase has been identified in Campylobacter jejuni. [aminoglycoside 2''-phosphotransferase] (Mus musculus) PubMed

 11274.

under nucleolar stress, the HBx oncoprotein down-regulates p53 and p21 [HBx] (Mus musculus) PubMed

 11275.

TaAQP7 confers drought stress tolerance in transgenic tobacco.[TaAQP7] (Mus musculus) PubMed

 11276.

PbDmc1 plays a critical role in malaria transmission biology.[PbDMC1] (Mus musculus) PubMed

 11277.

contribution to transport and localization of subtypes N1, N2 and N8 to the plasma membrane [neuraminidase] (Mus musculus) PubMed

 11278.

a TER that binds the C/D snoRNA core proteins [telomerase] (Mus musculus) PubMed

 11279.

These findings demonstrate that autoinducer 2 can decrease biofilm formation in Staphylococcus aureus via an icaR-activation pathway.[IcaR] (Mus musculus) PubMed

 11280.

SRO1c identified as a direct target gene of SNAC1 involved in the regulation of stomatal aperture and oxidative response.[SRO1c, SNAC1] (Mus musculus) PubMed

 11281.

The Thermus thermophilus HB27 mgh gene encoded a putative enzyme (TTC0614), mannosylglycerate hydrolase, with motifs of the GH63 & GH37 families of glycoside hydrolase which hydrolyzed mannosylglycerate and glucosylglycerate. MGH. (Mus musculus) PubMed

 11282.

Taken together, these results demonstrate that D1 and TUD1 act together to mediate a BR-signaling pathway. (Mus musculus) PubMed

 11283.

Coordinate hyperproduction of SmeZ and SmeJK efflux pumps extends drug resistance in Stenotrophomonas maltophilia. [SmeJ], [SmeK] (Mus musculus) PubMed

 11284.

When authors engineered a streptococcal strain to express the double-mutated streptolysin O, a drastic reduction in virulence as well as a diminished capacity to kill immune cells recruited at the infection site was observed.[streptolysin O] (Mus musculus) PubMed

 11285.

The transcriptional response of its four paralogous copies then analyzed revealed that they are not up-regulated, and hence do not compensate for the Tvhmp23 knockout (Mus musculus) PubMed

 11286.

OsNAC5 overexpression enlarges root diameter in rice plants leading to enhanced drought tolerance and increased grain yield in the field (Mus musculus) PubMed

 11287.

the primary structure-functional relationship between naturally occurring SK1 and SK2b [SK1][SK2b] (Mus musculus) PubMed

 11288.

substrate bound crystal structures of S-HPCDH [S-HPCDH] (Mus musculus) PubMed

 11289.

The MIA complex appears to regulate I1 dynein and possibly outer arm dyneins, which are both essential for normal motility.[MIA1, MIA1, L1 dynein] (Mus musculus) PubMed

 11290.

The BBSome is required only for the export phase of a process that continuously cycles PLD through cilia.[Phospholipase D] (Mus musculus) PubMed

 11291.

A comparison of the structure-function relationships of two paralogous single-stranded DNA-binding proteins, ssbB and ssbA(ssbB and ssbA). (Mus musculus) PubMed

 11292.

vraT is essential for optimal expression of methicillin resistance in vitro.[vraT] (Mus musculus) PubMed

 11293.

fmi-1 appears to be working in a novel pathway, independently from the planar cell polarity pathway and in parallel to lin-17/frizzled and dsh-1/dishevelled, to determine the direction of neurite growth.[Fmi-1] (Mus musculus) PubMed

 11294.

The study proposes that interaction of ligand with an arginine residue of PcaV dictates conformational changes that modulate DNA binding (PcaV). (Mus musculus) PubMed

 11295.

In rice the OsACS2-overexpression lines showed significantly increased levels of the OsACS2 transcripts, endogenous ethylene and defence gene expression, especially in response to Magnaporthe oryzae and Rhizoctonia solani infection. (Mus musculus) PubMed

 11296.

We conclude that Ehd4 is a novel Oryza-genus-specific regulator of Ehd1, and it plays an essential role in photoperiodic control of flowering time in rice. (Mus musculus) PubMed

 11297.

the TgRRM1 protein is an unrecognized and evolutionarily conserved class of splicing regulators (Mus musculus) PubMed

 11298.

Expression of TauT is differentially regulated by Vitamin D(3) and retinoic acid via formation of VDR and RXR complexes in the nuclei in a cell type-dependent manner.[TAUT] (Mus musculus) PubMed

 11299.

After adjustment by age, gender, and cagA, the presence of intact long-type dupA was significantly associated with gastric ulcer and gastric cancer compared with gastritis.[dupA] (Mus musculus) PubMed

 11300.

We show that MelR-dependent repression of the melR promoter can be enhanced by the presence of a second single DNA site for MelR located up to 250 base pairs upstream. (Mus musculus) PubMed

 11301.

Authors demonstrate that Cryptococcus neoformans signals through the Rim101 transcription factor to regulate cell wall composition and the host-pathogen interface.[Rim101] (Mus musculus) PubMed

 11302.

The fingerloop domain is essential for Ffh function during cargo delivery and unloading in cotranslational protein targeting. [Ffh] (Mus musculus) PubMed

 11303.

The lpa1 (Loose Plant Architecture1) mutant displays reduced shoot gravitropism. [LPA1] (Mus musculus) PubMed

 11304.

FtsZ guides the divisome to adopt a similar localization pattern to ensure Z ring constriction only proceeds following the assembly of a mature divisome.[FtsZ] (Mus musculus) PubMed

 11305.

The new acid/base catalyst of a glycoside hydrolase family 3 (GH3) beta-glucosidase from Aspergillus niger ASKU28 has been described. [GH3 beta-glucosidase] (Mus musculus) PubMed

 11306.

we have shown that chlorpromazine, a pharmacological agent, blocks Hb internalization in Leishmania by depolymerizing Ld-CHC and thereby inhibits the growth of the parasites. (Mus musculus) PubMed

 11307.

Expression analysis of BM7a of Bombyx mori nucleopolyhedrovirus revealed the protein is a component of the budded virions. [BM7a] (Mus musculus) PubMed

 11308.

Rice grain quality was dependent on the TRX h accumulation level. Increased TRX h expression resulted in aberrant phenotypes, such as chalky and shriveled features, lower seed weight and lower seed protein content in rice. (Mus musculus) PubMed

 11309.

PT13 AND PT11 are associated with the development of arbuscular mycorrhizal symbiosis. [2 genes- PT13 & PT11] (Mus musculus) PubMed

 11310.

The cooperation of the DnaK system with the upstream chaperone Trigger factor (TF) and the downstream GroEL, is reported.[DnaK] (Mus musculus) PubMed

 11311.

Overexpression of OsPAP10a significantly improved ATP hydrolysis and utilization compared with wild type plants.[OsPAP10a] (Mus musculus) PubMed

 11312.

Crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus in complex with ligands were solved, and together with site-directed mutagenesis and bioinformatics analyses, clearly reveal the catalytic mechanism of the enzyme.[PcrB] (Mus musculus) PubMed

 11313.

Authors suggest that interactions between ORF2 and DNA mediate certain aspects of the latency reactivation cycle.[ORF2] (Mus musculus) PubMed

 11314.

These observations extend previous indications that acidic pH causes the M1 layer to dissociate, leaving the envelope more pliable and, consequently, fusion compatible, and they show that dissociation is preceded by a conformational change in M1.[M1] (Mus musculus) PubMed

 11315.

Authors show via H1-ligand complex structures that the D225G substitution results in a loss of a salt bridge between amino acids D225 and K222, enabling the key residue Q226 to interact with the avian receptor, thereby obtaining dual receptor binding. (Mus musculus) PubMed

 11316.

Taking together the transcriptional analysis data and the biochemical evidences, authors surmise that the protein F55 is involved in the regulation of the lysogenic state of the virus.[F55] (Mus musculus) PubMed

 11317.

The rice GABA-T genes function in many processes, such as intracellular targeting, enzymatic activity and regulation of gene expression. (Mus musculus) PubMed

 11318.

Immune mapped protein 1 (IMP1) is likely to be a membrane protein of N. caninum and may be involved in parasite invasion. (Mus musculus) PubMed

 11319.

With the identification of residues in AgrB essential for AgrD processing, we reevaluated the membrane topology and the new model predicts four transmembrane helices and a potential re-entrant loop on the cytoplasmic face.[AgrB, AgrD] (Mus musculus) PubMed

 11320.

Altogether, these data support the model of ComE~P-dependent activation of transcription.[ComE] (Mus musculus) PubMed

 11321.

evidence that MiaB and RimO are true catalysts and support a new sulfation mechanism involving activation of an exogenous sulfur cosubstrate at an exchangeable coordination site on the second cluster, which remains intact during the reaction. (Mus musculus) PubMed

 11322.

Authors demonstrate that the virulent phenotype of was essentially associated with two amino acid changes, V8A and M136T, in the E2 glycoprotein, with the V8A change mostly being involved in the acquisition of the virulent phenotype.[E2] (Mus musculus) PubMed

 11323.

These results suggest mitochondrial TRM5 may be needed to mature unmethylated tRNAs that reach the mitochondria and that could pose a problem for translational fidelity. (Mus musculus) PubMed

 11324.

Authors found that the lysin of phage SV1 reaches the peptidoglycan through a novel holin-independent pathway and propose that the same mechanism could be used by other pneumococcal phages.[lysin] (Mus musculus) PubMed

 11325.

The results indicate that cagA genotypes may be important determinants in the development of gastroduodenal sequelae of H. pylori infection. In contrast to other studies, vacA genotypes were not related to disease progression or outcome (cagA, vacA). (Mus musculus) PubMed

 11326.

The substitution rate and evolution history of P gene is similar to G and N gene. [P protein] (Mus musculus) PubMed

 11327.

Together, these data demonstrated the importance of the HA-NA functional balance for influenza virus replication in an in vivo biological setting.[HA, NA] (Mus musculus) PubMed

 11328.

Indeterminate domain 10 (IDD10) is involved in regulatory circuits that determine N-mediated gene expression in plant roots. (Mus musculus) PubMed

 11329.

Deletion of PaClpP, leads to an unexpected healthy phenotype and increased lifespan of the fungal ageing model organism Podospora anserina and This phenotype can be reverted by expression of human ClpP.[ClpP] (Mus musculus) PubMed

 11330.

Rice OsSPL1 plays an important role in abiotic stress responses.[OsSPL1] (Mus musculus) PubMed

 11331.

crystal structure of a bacterial nitrate/nitrite transport protein, NarK, from Escherichia coli, with and without substrate [NarK] (Mus musculus) PubMed

 11332.

OsMIR444a-regulated OsMADS57, together with OsTB1, target D14 to control tillering.[OsMADS57, OsTB1, DWARF14] (Mus musculus) PubMed

 11333.

immotility in knockdowns affecting DNAH10 or IC138 results from loss of dynein-f function rather than from obvious structural defects in the axoneme [DNAH10, IC138] (Mus musculus) PubMed

 11334.

Inorganic phosphate transport and LiPho84 gene expression are modulated by environmental phosphate variations. [LiPho84], [LiPho89] (Mus musculus) PubMed

 11335.

TLP gene is required for survival of S. Typhimurium in a high uric acid environment such as chicken faeces [yedX] (Mus musculus) PubMed

 11336.

The results show tha sIHF (SCO1480) associates with the nucleoid and makes important contributions to chromosome condensation and chromosome segregation during Streptomyces sporulation (sIHF). (Mus musculus) PubMed

 11337.

Authors also demonstrate that SGK1 is required for influenza A virus ribonucleoprotein nuclear export. (Mus musculus) PubMed

 11338.

VPg was anchored at the bottom of the palm domain of the 3D(pol) molecule and exhibited an extended V-shape conformation.[VPg, 3Dpol] (Mus musculus) PubMed

 11339.

The interaction with epithelial cells revealed an opposite trend, suggesting that GOF mutations in CgPDR1 may favor epithelial colonization of the host by C. glabrata through increased adherence to epithelial cell layers. (Mus musculus) PubMed

 11340.

ETERNAL TAPETUM 1 promotes aspartic proteases triggering plant programmed cell death and reveals a dynamic regulatory cascade in male reproductive development in rice.[EAT1] (Mus musculus) PubMed

 11341.

Remarkably, while the core of feline calicivirus VPg contains a well-defined three-helix bundle, the murine norovirus VPg core has just the first two of these secondary structure elements.[VPg] (Mus musculus) PubMed

 11342.

Study shows that the glucose-6-P-responsive small RNA SgrS activates YigL synthesis in a translation-independent fashion by the selective stabilization of a decay intermediate of the dicistronic pldB-yigL messenger RNA (mRNA). (Mus musculus) PubMed

 11343.

HASPB repeat region (k26) shows considerable polymorphism among L. donovani strains from different regions in East Africa. [HASPB] (Mus musculus) PubMed

 11344.

The TerS DNA-binding domain is self-contained in that it apparently does not interact closely with the rest of the motor and it binds to a recognition site that lies within the DNA that encodes the domain.[TerS] (Mus musculus) PubMed

 11345.

We discuss these findings in light of the ancestral role of Wor1 as a transcriptional regulator of the transition between yeast form and filamentous growth. (Mus musculus) PubMed

 11346.

Specific interaction of the envelope glycoproteins E1 and E2 with liver heparan sulfate involved in the tissue tropismatic infection by hepatitis C viru (Mus musculus) PubMed

 11347.

M2 decreases CFTR activity by increasing secretory organelle pH, which targets CFTR for destruction by the ubiquitin system[M2 matrix protein] (Mus musculus) PubMed

 11348.

OmcBc protein is an immunodominant protein of Chlamydia trachomatis serovar D. [OmpBc] (Mus musculus) PubMed

 11349.

Functionally, both OsSAP11 and OsRLCK253 could improve the water-deficit and salt stress tolerance in transgenic Arabidopsis plants via a signaling pathway affecting the expression of several common endogenous genes. [OsSAP11 and OsRLCK253] (Mus musculus) PubMed

 11350.

Hydrogen bonds mainly through N101 for maintaining substrate binding stability and the hydrophobic interaction of M111 in dimer interface are essential for activity of geranylgeranyl diphosphate synthase.[geranylgeranyl diphosphate synthase ] (Mus musculus) PubMed

 11351.

A central metabolite of glucose catabolism, acetyl-CoA, induces CLN3 transcription by promoting the acetylation of histones present in its regulatory region.[CLN3] (Mus musculus) PubMed

 11352.

the yeast Sgs1-Dna2 and Exo1 pathways do not stimulate one another and function as independent and separate DNA end-processing machineries, even in the presence of the stimulatory Mre11-Rad50-Xrs2 complex.[Exo1, RPA, Mre11, Rad50, Xrs2] (Mus musculus) PubMed

 11353.

The values of the 14 binding constants of ATP to GroEL were determined, and the ATP-loading pathway of the chaperone was characterized.[GroEL] (Mus musculus) PubMed

 11354.

This is the first description of a determinant that contributes to intestinal colonization in clinical Enterococcus faecium strains.[pstD] (Mus musculus) PubMed

 11355.

Study showed qDTY12.1 a consistent effect across environments for high grain yield under lowland reproductive-stage drought stress in the background of popular high-yielding but drought-susceptible recipient variety Sabitri. [qDTY12.1] (Mus musculus) PubMed

 11356.

a structural transition in the Dictyostelium myosin II relay helix during the actin-activated power stroke, is reported.[Actin] (Mus musculus) PubMed

 11357.

This study demonistrated that Taste-independent nutrient selection is mediated by a brain-specific Na+ /solute co-transporter in Drosophila. (Mus musculus) PubMed

 11358.

CD169 and CD163 are identified as critical receptors porcine reproductive and respiratory syndrome virus on the surface of PAM, but whether the single nucleotide polymorphisms (SNPs (Mus musculus) PubMed

 11359.

Ehx plays a crucial role in EHEC O157:H7-induced IL-1beta production and its cytotoxicity to THP-1 cells and activation of NLRP3 inflammasome [Ehx] (Mus musculus) PubMed

 11360.

results demonstrate the complex role of Ca2 binding proteins, EhCaBP1 and EhCaBP3 in regulation of phagocytosis and an unusual mechanism of modulation of cytoskeleton dynamics by EhCaBP1 and EhCaBP3 with mostly non-overlapping functions [CaBP3] (Mus musculus) PubMed

 11361.

McoA, McoB and McoG were monomers with apparent molecular masses ranging from 80 to 110 kDa and with different substrate specificity. [McoA, McoB and McoG] (Mus musculus) PubMed

 11362.

The buried in the P phosphoprotein structure tryptophan (Trp 135) is involved in the interaction with the the viral leader (le) RNA. [P phosphoprotein] (Mus musculus) PubMed

 11363.

Activation of the jasmonic acid pathway by depletion of the hydroperoxide lyase OsHPL3 reveals crosstalk between the HPL and AOS branches of the oxylipin pathway in rice [HPL3] (Mus musculus) PubMed

 11364.

Crystallographic and NMR spectroscopy analyses revealed that an asymmetric interface between Ile44 and Ile36 hydrophobic patches of neighboring ubiquitin moieties is propagated by NleL in longer Lys6-linked ubiquitin chains. (Mus musculus) PubMed

 11365.

determined the complex structures of wild-type and mutant HAs derived from an Indonesia H5N1 virus bound to avian or human receptor sialic acid analogs; findings provide a structural and biophysical basis for H5N1 adaptation to acquire human, but maintain avian, receptor-binding properties[H5] (Mus musculus) PubMed

 11366.

data suggest that several cepR2-linked promoters are repressed by CepR2 and that CepR2 is antagonized by octanoylhomoserine lactone [CepR2] (Mus musculus) PubMed

 11367.

MyoD expression may be regulated by miRNAs. Predictions from bioinformatics have identified a putative miR-203b target site in the 3'-UTR of the MyoD gene. [MyoD] (Mus musculus) PubMed

 11368.

These results indicate that cytidylate kinase plays an important role in normal nucleotide biosynthesis under an oxygen-limiting environment.[cytidylate kinase] (Mus musculus) PubMed

 11369.

Wapl controls cohesion maintenance after its establishment in S phase and adjusts the chromosome condensation status. (Mus musculus) PubMed

 11370.

OsSNDP1 is involved in growth of root hairs. [OsSNDP1] (Mus musculus) PubMed

 11371.

Authors propose that linking Mus81-Eme1 DNA damage-induced activation to cell-cycle progression ensures efficient resolution of Holliday junctions that escape dissolution by Rqh1-TopIII while preventing unnecessary DNA cleavages.[Mus81, Eme1] (Mus musculus) PubMed

 11372.

These results validate TgAP2XI-4 as a novel nuclear factor that regulates bradyzoite gene expression during parasite differentiation and cyst formation.[TgAP2XI-4] (Mus musculus) PubMed

 11373.

Cystathionine gamma-synthase(FGMETB) is essential for methionine biosynsthesis, and plays a critical role in the regulation of various cellular processes F. graminearum.[METB] (Mus musculus) PubMed

 11374.

Reduced phosphatidylglycerophosphate synthase expression leads to alterations in mitochondrial morphology, reduction in the amounts of respiratory complexes III and IV and, ultimately, parasite death.[phosphatidylglycerophosphate synthase] (Mus musculus) PubMed

 11375.

A time-dependent Na-dependent glutamate/aspartate transporter/EAAT1-induced System N-mediated glutamine release could be demonstrated in Bergmann glia.[eaat1] (Mus musculus) PubMed

 11376.

Phosphorylation of RpaA is regulated by two antagonistic histidine kinases, SasA and CikA. [CikA] (Mus musculus) PubMed

 11377.

Authors show that heterochromatin differs from euchromatin in histone turnover and identify histone deacetylase Clr3 as a factor required for inhibiting histone turnover across heterochromatin domains in Schizosaccharomyces pombe.[Clr3] (Mus musculus) PubMed

 11378.

The recombinant TspSP-1.2 protein induced a partial protective immunity in mice and could be considered as a potential vaccine candidate against T. spiralis infection[TspSP-1.2] (Mus musculus) PubMed

 11379.

findings show that XanB2 is a unique bifunctional chorismatase that hydrolyses chorismate, the end-product of the shikimate pathway, to produce 3-hydroxybenzoic acid (3-HBA) and 4-HBA[XanB2] (Mus musculus) PubMed

 11380.

Authors report that group A Streptococcus biofilm formation is mediated by the Scl1 interaction with extra domain A-containing cellular form of fibronectin. (Mus musculus) PubMed

 11381.

TbOrc1 has conserved functions in DNA replication and is also required to control telomere-linked Variant Surface Glycoprotein expression and Variant Surface Glycoprotein switching. [Orc1] (Mus musculus) PubMed

 11382.

Data indicate that the T-helper-inducing POZ/Kruppel-like factor (Th-POK) gene (ZBTB7B; AB744092) was composed of three exons and two introns, and its structure was identical to that of its human counterpart: [Th-POK] (Mus musculus) PubMed

 11383.

The role of one of the group IIa WRKY transcription factors in rice, OsWRKY28, in the regulation of basal defense responses to a compatible race of the rice blast fungus Magnaporthe oryzae, was investigated.[OsWRKY28] (Mus musculus) PubMed

 11384.

[ExeB] The crystal structure of EpsAB periplasmic domain of type II secretion system protein (amino acids 333-584) is presented; ExeB and ExeA are fused into one protein EpsAB, the crystals of which diffract to 1.55 A resolution. (Mus musculus) PubMed

 11385.

V protein of TioV (TioV-V) hardly interacts with human STAT2, does not degrade STAT1, and cannot block IFN-alpha/beta signaling in human cells. (Mus musculus) PubMed

 11386.

SSITL is an effector possibly and plays significant role in the suppression of jasmonic/ethylene (JA/ET) signal pathway mediated resistance at the early stage of infection (Mus musculus) PubMed

 11387.

These observations indicate a bifunctional protective role of secretory Prx; first it reduces redox activation of macrophages, and secondly it allows iron access to Leishmania by down regulating NRAMP1 expression.[Peroxidase] (Mus musculus) PubMed

 11388.

Together, this study identified and characterized a novel periplasmic trilactone esterase and suggested a new model of ferric enterobactin acquisition in Campylobacter jejuni.[trilactone esterase] (Mus musculus) PubMed

 11389.

IsaB expression was stimulated by glucose, human serum and plasma, and transcript levels increased in the absence of the SarA and decreased in the absence of CcpA. [IsaB, ccpA, SarA] (Mus musculus) PubMed

 11390.

The phenotypes of cmpR-deficient cells were attributable mainly to a feeble metabolic and/or redox status.[CmpR] (Mus musculus) PubMed

 11391.

The highly immunogenic p28 contains a linear epitope that is detergent-stable and is not altered by beta-ME treatment, whereas the p55(gag) epitope contains a linear epitope susceptible to denaturing agents.[p28, p55] (Mus musculus) PubMed

 11392.

Recombinant TcPINK1 efficiently phosphorylates only one human Parkinson-disease associated proteins, parkin. PINK1. (Mus musculus) PubMed

 11393.

study identifies SlPatA, a GCN5-type N-acetyltransferases with unique domain organization, and a new acetylation target, acetoacetyl-CoA synthetase (SlAacS)[SlAacS, SlPatA] (Mus musculus) PubMed

 11394.

results indicate that exported LISP2 is involved in parasite-host interactions required for the development of liver-stage parasites inside hepatocytes [LISP2] (Mus musculus) PubMed

 11395.

Atg36 is a novel pexophagy receptor that may target peroxisomes for degradation via a noncanonical mechanism.[Atg36] (Mus musculus) PubMed

 11396.

genome-wide binding profile of Hmt1 [Hmt1] (Mus musculus) PubMed

 11397.

Electron spin resonance spectroscopy study of spin-labeled colicin A variants in the membrane-bound closed channel state reveals a conformational equilibrium with resolved interhelical tertiary contacts. (colicin A) (Mus musculus) PubMed

 11398.

Sis1 and Hsp70 operate sequentially with the quality control E3 ubiquitin ligase Ubr1 to target short-lived green fluorescent protein for degradation.[Ubr1] (Mus musculus) PubMed

 11399.

the two AGS genes are dispensable in A. nidulans, but that AgsB is required for normal growth characteristics under liquid culture conditions and is the major AGS in this species. [agsA; agsB] (Mus musculus) PubMed

 11400.

This report demonstrates that RNAP-II also transcribes two sequences located in the 5'- and 3'-ends of the 35S rRNA gene that overlap with the sequences of the 35S rRNA precursor transcribed by RNAP-I.[RNAP-II] (Mus musculus) PubMed

 11401.

The structure of the SecYEG complex unlocked by the preprotein, is reported.[SecY, SecE, SecG] (Mus musculus) PubMed

 11402.

Sequences with amino acids of simple shape and small size impair unfolding of contiguous stable domains mediated by E. coli ClpX protein [ClpX] (Mus musculus) PubMed

 11403.

FlgT, which is a flagellar protein specific for Vibrio sp., is required to form and stabilize both the T ring and the H ring structures [FlgT] (Mus musculus) PubMed

 11404.

F18ab E. coli strongly binds to pig epithelial cell and wild-type F18ac binds to these cell but not as strongly as F18ab strain. [F18ab, F18ac] (Mus musculus) PubMed

 11405.

An N-terminal 106-amino acid segment within P1 contributes to the proper folding and function of the full-length recombinant molecule and increases the stability of its elongated hybrid helical stalk. [P1] (Mus musculus) PubMed

 11406.

Est24 is a novel SGNH hydrolase and exhibited optimum activity at mesophilic temperature ranges (45-55 degrees C), and slightly alkaline pH. [Est24] (Mus musculus) PubMed

 11407.

The 1.7A resolution crystallographic structure of the Thermotoga maritima BeF(3)(-)-activated CheY in complex with the CheY-binding N-terminal region of FliM, is reported.[FliM, CheY] (Mus musculus) PubMed

 11408.

new putative targets under Tel1/Mec1 control [Tel1][Mec1] (Mus musculus) PubMed

 11409.

Six different genes involved in development and immunity are regulated by aae-miR-375 at the post-transcriptional level. [Mir-375] (Mus musculus) PubMed

 11410.

both H(2)O(2) and heme oxygenase (HO) are required for apocynin-induced LR formation in rice. [OsHO1] (Mus musculus) PubMed

 11411.

The heat shock transcription factor subfamily C showed a strong positive association with drought, salt and cold stresses in rice. (Mus musculus) PubMed

 11412.

MoCel7B is a member of the glycoside hydrolase 7 family of endotransglucosylases. [MoCel7B] (Mus musculus) PubMed

 11413.

this study presents a crystal structure at 3 angstrom resolution of the Thermus thermophilus ribosome with a tRNA in the hybrid P/E state bound to EF-G with a GTP analog.[EF-G] (Mus musculus) PubMed

 11414.

Trp-40 is essential for chain end loading to initiate processive hydrolysis of TrCel7A. [Cel7A] (Mus musculus) PubMed

 11415.

(EMP1) EMP1 variant from the FCR3 parasite line causes sequestration of infected erythrocytes in the intervillous spaces of the placenta and leads to pregnancy-associated malaria, with severe consequences for fetus and mother (Mus musculus) PubMed

 11416.

a novel betagamma-crystallin domain with S-type (Spherulin 3a type) Greek key motifs in protein vibrillin from a pathogenic bacterium Vibrio cholerae [vibrillin] (Mus musculus) PubMed

 11417.

The crystal structure of the alpha-hemolysin:LTM14 Fab antigen-antibody complex shows that the antibody binds alpha-hemolysin between the cap and the rim domains. (alpha-hemolysin) (Mus musculus) PubMed

 11418.

Terminal RNA stem length and bulge motif are critical for Ku (high affinity DNA-binding factor) recognition. [Ku] (Mus musculus) PubMed

 11419.

The C2-domain of Inn1 acts in conjunction with Cyk3 to regulate the catalytic domain of Chs2 during cytokinesis.[Inn1, Cyk3, Chs2] (Mus musculus) PubMed

 11420.

The crystal structure of BF2*2101 was determined to to 2.6 A resolution.[BF2*2101] (Mus musculus) PubMed

 11421.

In this study, dogs and cats harbored E. coli carrying CTX-M-1, CMY-2, and QnrB19, all drug resistance genes of interest in human health.[CTX-M-1; CMY-2; QnrB19] (Mus musculus) PubMed

 11422.

The crystal structure of an amidohydrolase, SACOL0085, from S. aureus COL is described.[SACOL0085] (Mus musculus) PubMed

 11423.

Structural analysis of NagA from Thermotoga maritima encoded by the Tm0809 gene was initiated.[Tm0809] (Mus musculus) PubMed

 11424.

The C-terminal regulatory domain of Upc2 crystals from Saccharomyces cerevisiae diffracted to 2.9 A resolution.[Upc2] (Mus musculus) PubMed

 11425.

Preliminary analysis of the diffraction data suggests the presence of approximately three to seven molecules of YhbJ per asymmetric unit.[YhbJ] (Mus musculus) PubMed

 11426.

It was found that the ecm17Delta/Delta mutant failed to catalyze the biochemical reaction from sulfite to H(2)S and hardly grew in media lacking Met and Cys.[ecm17] (Mus musculus) PubMed

 11427.

XccEG crystals diffracted to 2.7 A resolution.[XccEG] (Mus musculus) PubMed

 11428.

These results suggest that the SERT's function is primarily neuromuscular and may also play a secondary role in the uptake of exogenous (host-derived) serotonin.[SERT] (Mus musculus) PubMed

 11429.

The recombinant DasD protein produced in Escherichia coli showed N-acetyl-beta-d-glucosaminidase (GlcNAcase) activity and its optimum temperature and pH were 40 degrees C and 7, respectively.[DasD] (Mus musculus) PubMed

 11430.

Authors show that MurC is phosphorylated by StkP and that phosphoMurC is dephosphorylated by PhpP.[StkP, PhpP] (Mus musculus) PubMed

 11431.

Opp1 imports nickel and cobalt in zinc-depleted conditions and contributes to virulence. [Opp1] (Mus musculus) PubMed

 11432.

An Atg10-like E2 enzyme is essential for cell cycle progression but not autophagy in Schizosaccharomyces pombe. [Atg10] (Mus musculus) PubMed

 11433.

DNF2 encodes a putative phosphatidylinositol phospholipase C-like protein involved in nitrogen fixation. (Mus musculus) PubMed

 11434.

The findings presented here suggest a protective role for HSP90 during adaptation to hostile environments, one that promotes survival of the fungus during host-pathogen interactions.[HSP90] (Mus musculus) PubMed

 11435.

PpAOS1 allene oxide synthase is essential for wound-induced accumulation of cis(+)-12-oxo phytodienoic acid while PpAOS2 appears not to be involved in the process. [PpAOS1; PpAOS2] (Mus musculus) PubMed

 11436.

The study provides empirical evidence for the in silico predicted functions of specific amino acids in AgamOBP1 folding and ligand binding characteristics (AgamOBP1). (Mus musculus) PubMed

 11437.

ABCG15 encodes an ABC transporter protein, and is essential for post-meiotic anther and pollen exine development in rice.[ABCG15] (Mus musculus) PubMed

 11438.

DGL1 is involved in N-glycosylation and root development.[DGL1] (Mus musculus) PubMed

 11439.

These results indicate that Ca(2+) waves initiate where there is a structural and functional coupling of mAChR3 and InsP(3)R1.[InsP(3)R1, mACHR3] (Mus musculus) PubMed

 11440.

We hypothesize that in addition to its function as a disease marker, Snord3A may play an important role in the mechanism of prion disease manifestation and progression (Mus musculus) PubMed

 11441.

Study suggests that the predominant expression of Elovl5b in salmon liver and Elovl5a in salmon intestine is an adaptation, enabled by genome duplication, to a diet rich in terrestrial invertebrates which are relatively poor in long chain polyunsaturated fatty acids.[Elovl5a] (Mus musculus) PubMed

 11442.

The ability of the malarial protein to function in E. coli suggests that this simple system can be used as a tool for further analyses of Pf-cpn20 and perhaps other chaperone proteins from P. falciparum. (Mus musculus) PubMed

 11443.

Our analysis showed that all three possible forms of the mitochondrial ATP synthase subnit c were detected in both procyclic and bloodstream stages, although the c-3 transcript was less abundant than that for c-1 or c-2 (Mus musculus) PubMed

 11444.

Autophagy genes Smatg8 and Smatg4 are required for fruiting-body development, vegetative growth and ascospore germination. (atg8 and atg4) (Mus musculus) PubMed

 11445.

The non-specific lipid transfer protein N5 is involved in the control of rhizobial infection by restricting the invasion at the root epidermis and promoting the infection in the root cortex. [MtN5] (Mus musculus) PubMed

 11446.

These data establish a strict requirement for dUTPase in Trypanosoma brucei viability and support a major role of the enzyme in the provision of pyrimidine nucleotides in kinetoplastids.[dUTPase] (Mus musculus) PubMed

 11447.

function of the multi-domain di-heme cytochrome c(550)[cytochrome c550] (Mus musculus) PubMed

 11448.

The results indicate that L273P amino acid substitution confers KlPdr1p hyperactivity, as revealed by a high expression of the ABC transporter gene KlPDR5, leading to multidrug resistance and rhodamine 6G efflux out of the cells.[KlPdr1] (Mus musculus) PubMed

 11449.

the fundamental role of VhChiP in the chitin catabolic cascade as the molecular gateway that Vibrios employ for chitooligosaccharide uptake for energy production [chitoporin] (Mus musculus) PubMed

 11450.

miRNA164 negatively regulates ZmNAC1 expression. [miR164] (Mus musculus) PubMed

 11451.

in the presence of CO2, female orco mutant mosquitoes retain strong attraction to both human and animal hosts, but no longer strongly prefer humans [orco] (Mus musculus) PubMed

 11452.

The 54K protein interacts with the virus-specific coat protein (CP) in the cytoplasm, suggesting a potential role of CP in ophiovirus movement.[54K, CP] (Mus musculus) PubMed

 11453.

Wor3 is highly integrated into the previously described circuit regulating white-opaque switching and it controls a subset of the opaque transcriptional program [Wor3] (Mus musculus) PubMed

 11454.

In this report, we identify a Gas7 gene in zebrafish that we termed zfGas7. (Mus musculus) PubMed

 11455.

the importance of asparagine and K(+)-dependent NSE1 asparaginase for nitrogen remobilization and seed production in L. japonicus plants [NSE1 asparaginase] (Mus musculus) PubMed

 11456.

Data indicate that the Young Leaf Chlorosis 1 (YLC1, LOC_Os09g21250) protein displayed a chloroplast location pattern in protoplast: [YLC1] (Mus musculus) PubMed

 11457.

The catalytic P loop forms a positively charged, shallow pocket that is approximately 9 A deep.[protein tyrosine phosphatase 1] (Mus musculus) PubMed

 11458.

Rim15, phosphorylates endosulfines to directly inhibit the Cdc55-protein phosphatase 2A.[Cdc55, Igo1, Igo2] (Mus musculus) PubMed

 11459.

The crystal structures of the homodimeric glycoprotein E2 from the pestivirus bovine viral diarrhea virus 1 (BVDV1) at both neutral and low pH, are reported.[E2] (Mus musculus) PubMed

 11460.

We thereby identified 10 rice genes as putative DREB1 homologs: nine of these were located in rice genomic regions with some colinearity to the Arabidopsis CBF1-CBF4 region. ...with similarly expression in response to chilling acclimation and cold stress (Mus musculus) PubMed

 11461.

Cox subunit Cox1p and the two other mitochondrial gene products, Cox2p and Cox3p, constitute independent assembly modules, each with its own complement of subunits. [Cox1p] (Mus musculus) PubMed

 11462.

MtABCG10 silencing increases M. truncatula susceptibility to Fusarium oxysporum.[ABCG10] (Mus musculus) PubMed

 11463.

Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1. [gp41] (Mus musculus) PubMed

 11464.

It seems that overexpression of udk reduces Gp2 stability and functionality during T7 infection, which consequently results in inadequate inhibition of host RNAp and in the accumulation of early T7 transcripts.[Gp2] (Mus musculus) PubMed

 11465.

The FlaB flagellin protein from S. oneidensis is propsed to be modified at five serine residues with a series of novel O-linked posttranslational modifications (PTMs) that differ from each other by 14 Da. [FlaB] (Mus musculus) PubMed

 11466.

Data indicate that the mutation of glycosyltransferase1 (OsGT1) leads to a male gametophyte defect: [OsGT1] (Mus musculus) PubMed

 11467.

(metacaspase 2) T. brucei TbMCA2 gene has a strict preference for basic charged amino acids (Arg or Lys) at the P1 position, with a preference for Arg. (Mus musculus) PubMed

 11468.

AChE2 may play a less significant role than AChE1 does in the mosquito nervous system. [AChE2] (Mus musculus) PubMed

 11469.

Downregulation of hccs causes increased cell death via an apoptosome-independent caspase-9 activation in brain and eyes. (Mus musculus) PubMed

 11470.

These results suggest that dpr and sod in Streptococcus mutans are involved in coexistence with Streptococcus sanguinis, and PerR is associated with resistance to H(2)O(2) in regulating the expression of Dpr.[PerR] (Mus musculus) PubMed

 11471.

HtrA2-knockout cells exhibit increased proton translocation through the ATP synthase, in combination with decreased ATP production and truncation of the F1 alpha-subunit, suggesting the ATP synthase as the source of the proton leak. [F1F0-ATP synthase] (Mus musculus) PubMed

 11472.

the presence of a highly conserved glycine residue in nucleotide binding domain of ComA [ComA] (Mus musculus) PubMed

 11473.

SseL binds the N-terminus of OSBP and that S. Typhimurium infection results in redistribution of OSBP. [SseL] (Mus musculus) PubMed

 11474.

FOXO was much more abundant in the fat body of diapausing females than in the fat body of nondiapausing females.[FOXO] (Mus musculus) PubMed

 11475.

McaS is a dual-function sRNA with roles in the two major post-transcriptional regulons controlled by the RNA-binding proteins Hfq and CsrA (Mus musculus) PubMed

 11476.

Based on this, it was concluded that sha4 was a true K+/H+ antiporter.[sha4] (Mus musculus) PubMed

 11477.

Cloning, expression analysis and subcellular localization of 2 novel katG1 genes from the soil fungi Chaetomium globosum and Chaetomium cochliodes are reported.[Katg1] (Mus musculus) PubMed

 11478.

X-ray crystallographic analysis of the Staphylococcus epidermidis extracellular serine protease Esp structure [serine protease Esp] (Mus musculus) PubMed

 11479.

Data indicate that FsrC is 61% alpha-helical and that it is relatively thermostable, retaining at least 57% secondary structural integrity at 90 degrees C: [FsrC] (Mus musculus) PubMed

 11480.

X-ray crystallographic analysis of the UDP-glucuronic acid:flavonol-3-O-glucuronosyltransferase structure [UDP-glucuronic acid:flavonol-3-O-glucuronosyltransferase] (Mus musculus) PubMed

 11481.

X-ray crystallographic analysis of the polyadenylate synthase structure (Mus musculus) PubMed

 11482.

The 70S ribosome modulates the ATPase activity of Escherichia coli MRE600 YchF. [YchF] (Mus musculus) PubMed

 11483.

Reticulocalbin is preferentially expressed in the mushroom body in the honeybee brain.[reticulocalbin] (Mus musculus) PubMed

 11484.

A nonconserved critical residue Phe534 on helicase binding interface of DnaG C-terminal domain was identified.[DnaG] (Mus musculus) PubMed

 11485.

In vitro assays indicate that CPT1 has high cholinephosphotransferase (CPT) activity but no ethanolaminephosphotransferase (EPT) activity.[CPT1] (Mus musculus) PubMed

 11486.

Nascent polypeptide-associated complex (NAC) has a central role as a proteostasis sensor to provide the cell with a regulatory feedback mechanism in which translational activity is controlled by the folding state of the cellular proteome (NAC alpha and beta subunits). (Mus musculus) PubMed

 11487.

FnBPA mediates biofilm formation and bacterial adhesion to fibrinogen using two distinct mechanisms. [FnBPA, strain BH1CC] (Mus musculus) PubMed

 11488.

AfaR is a trans-acting Hfq-dependent antisense small RNA that binds the 5' untranslated region of the afaD messenger RNA, initiating several ribonuclease E-dependent cleavages, thereby downregulating production of the AfaD-VIII invasin (AfaR and AfaD). (Mus musculus) PubMed

 11489.

Two interacting regulators, Cra and KdpE, play a role in EHEC pathogenesis and global gene regulation. [Cra] (Mus musculus) PubMed

 11490.

Thus, the SMU.1147-encoded peptide affects virulence-related traits and dominantly controls quorum-sensing pathways for development of genetic competence in Streptococcus mutans.[SMU.1147] (Mus musculus) PubMed

 11491.

Orf2 and Orf29 function as the chaperones of the needle protein, and therefore, they have been renamed EscE and EscG. [EscE and EscG] (Mus musculus) PubMed

 11492.

OsGLK1 and OsGLK2 regulate chloroplast development in both bundle sheath and mesophyll cells.[GLK1 (golden2-like 1 protein);GLK2 (golden2-like 2 protein)] (Mus musculus) PubMed

 11493.

Coactosin participates in actin polymerization and functions under Rac signaling. [Coactosin] (Mus musculus) PubMed

 11494.

The structure points to a means by which c-di-GMP and PilZ binding could be coupled to FimX and PilB conformational states.[FimX] (Mus musculus) PubMed

 11495.

Our findings suggest that NiV N expression is repressed by hnRNP D through the NiV N 3' UTR and demonstrate the involvement of posttranscriptional regulation in the NiV life cycle. [hnRNP D] (Mus musculus) PubMed

 11496.

This study identifies TgMAPK1, a Toxoplasma mitogen-activated protein kinase (MAPK), as a virulence factor regulating tissue-specific parasite burden by manipulating host interferon (IFN)-gamma-mediated inducible nitric oxide synthase[TgMAPK1]. (Mus musculus) PubMed

 11497.

AmpG is required for Bla expression. [AmpG, Bla] (Mus musculus) PubMed

 11498.

This study suggests that both F4 homo- and heterozygous susceptible pigs have similar functional receptors for E. coli F4, F4 receptors (F4R), which facilitate the adhesion of F4 to the intestinal tissue.[F4R] (Mus musculus) PubMed

 11499.

This study demonstrated that, in addition to atf1 gene, atf2 is actively involved in triacylglycerol accumulation by the oleaginous Rhodococcus opacus PD630.[atf2] (Mus musculus) PubMed

 11500.

Thus, the physiological changes in the csrA mutant may be similar to carbon source limitation for initiating the expression of ColE7 operon in response to stringent environmental conditions.[ColE7] (Mus musculus) PubMed

 11501.

The product encoded by the Bcam1330-Bcam1341 gene cluster is a major exopolysaccharide and its production is regulated by c-di-GMP through binding to the transcriptional regulator Bcam1349.[Bam1349] (Mus musculus) PubMed

 11502.

[envelope protein gp120] Gp120 significantly upregulates Nrf2 in human astrocytes and is associated with stimulation of key antioxidant defensive enzymes. (Mus musculus) PubMed

 11503.

IVa2, 33K and DBP form a complex at a unique vertex on viral capsids and cooperate in genome packaging. [L433K] (Mus musculus) PubMed

 11504.

Photoreceptor apoptosis in the beta-SNAP mutant was dependent on the BH3-only protein BNip1.[BNip1;beta-SNAP] (Mus musculus) PubMed

 11505.

Met58 is crucial in the regulation of the functional mechanism of PpcA. [PpcA] (Mus musculus) PubMed

 11506.

Analyses of gene expression demonstrated that LRK1 restricts gibberellin biosynthesis during the internode elongation process by down-regulation of the gibberellin biosynthetic gene coding for ent-kaurene oxidase. (Mus musculus) PubMed

 11507.

Lysophosphatidic acid produced by hen egg white lysophospholipase D is involved in the formation of blood vessel networks through several lysophosphatidic acid receptors on various extraembryonic membranes. [lysophospholipase D] (Mus musculus) PubMed

 11508.

TGW6 (gene annotation Os06g0623700) encodes an IAA-glucose hydrolase and loss of function enhances grain weight and increases yield in Oryza sativa. [TGW6] (Mus musculus) PubMed

 11509.

Iron binding activity is essential for the function of IscA in iron-sulphur cluster biogenesis. (Mus musculus) PubMed

 11510.

The antigenic region was identified at the C terminus of the ORF1 protein. [ORF1] (Mus musculus) PubMed

 11511.

OsARF16 is required for auxin responses in roots, and is an essential regulator in the phosphate response. [ARF16] (Mus musculus) PubMed

 11512.

CsSEF1 might be involved in the signal transduction pathway from photoassimilate limitation to growth cessation in cucumber fruit.[CsSEF1] (Mus musculus) PubMed

 11513.

TbPT0 is a unique monocarboxylate transporter with preference for pyruvate and essential for bloodstream form viability [TbPT0] (Mus musculus) PubMed

 11514.

A model of an HSV-1 ICP8-ssDNA binary complex provides insight into the basic strand annealing mechanism (ICP8). (Mus musculus) PubMed

 11515.

deleting variant-silencing PfSETvs that controls histone H3 lysine 36 trimethylation on var genes, results in transcription of virtually all var genes in the single parasite nuclei and their expression as proteins on the surface of individual infected RBCs [SETvs] (Mus musculus) PubMed

 11516.

Immunofluorescence assays using the tachyzoite-specific Mab for NcSAG1 and the bradyzoite-specific Mab for TgBAG1 or NcSAG4 revealed NcBAG1-specific expression in bradyzoites in cultures exposed to sodium nitroprusside[BAG1] (Mus musculus) PubMed

 11517.

RNA repair by AlkB takes place in endogenous RNA as part of an adaptive response in wild-type E. coli cells. (Mus musculus) PubMed

 11518.

OsNPR1 is an early responding gene in herbivore-induced defense and that plants can use it to activate a specific and appropriate defense response against invaders by modulating signaling pathways. [OsNPR1] (Mus musculus) PubMed

 11519.

[putrescine-cadaverine permease; POT1] Tcpot1.1 mutants are evaluated for their ability to transport putrescine as well as for proper targeting of the mutated transporters to the cell surface of the parasite/ (Mus musculus) PubMed

 11520.

The recombinant OsCLP did not display inhibitory activity against endo-1,4-beta-xylanase enzymes from Aureobasidium pullulans or Trichoderma viride and an in-gel activity assay revealed strong chitinase activity.(chitinase-like protein) (Mus musculus) PubMed

 11521.

A new MADS-box gene, BdMADS2, was found in Brachypodium distachyon which plays an essential role in ovule identity determination. (Mus musculus) PubMed

 11522.

Aspergillus nidulans LaeA protein methylation generates S-methylmethionine [LaeA] (Mus musculus) PubMed

 11523.

TaSSI2 is involved in the negative regulation of defense responses in powdery mildew infection. (Mus musculus) PubMed

 11524.

Dementin was required for normal development of the brain, and that glial Dementin was required for development of the Drosophila medulla neuropil. (Mus musculus) PubMed

 11525.

Wheat expressing SNAC1 displayed significantly enhanced tolerance to drought and salinity in multiple generations, and contained higher levels of water and chlorophyll in their leaves, as compared to wild type. (Mus musculus) PubMed

 11526.

TaGID1-A1, TaGID1-B1, TaGID1-D1 are homologous genes found in wheat which function as gibberellin receptors (TaGID1-A1, TaGID1-B1, TaGID1-D1). (Mus musculus) PubMed

 11527.

PEDV papain-like protease 2 acts as a viral deubiqutinase to interfere with the RIG-I- and STING-mediated signalling pathway for interferon beta expression. {PLP2] (Mus musculus) PubMed

 11528.

Authors show that another critical cell cycle regulator, SciP, is also degraded during the G1-S transition, but by the Lon protease.[SciP, Lon] (Mus musculus) PubMed

 11529.

The authors cloned cytosolic glutathione peroxidase (GPx1) and phospholipid hydroperoxide glutathione peroxidase (GPx4) genes in rainbow trout (Oncorhynchus mykiss). Constitutive mRNA expression and responsiveness to Se availability was analysed.[gpx4] (Mus musculus) PubMed

 11530.

Both clinical and mouse infection data support the idea that nD222 mutations contribute to increased severity of disease but additional determinants in disease outcome may be present.[HA] (Mus musculus) PubMed

 11531.

Authors showed that the expression of the RabB protein, a small GTPase involved in phagocytosis, is modified through the interaction with red blood cells.[RabB] (Mus musculus) PubMed

 11532.

Disruption of a galactoglycerolipid lipase-encoding gene (PGD1) was responsible for the primary phenotype: reduced TAG content, altered triacylglycerols (TAGs) composition, and reduced galactoglycerolipid turnover. [PGD1] (Mus musculus) PubMed

 11533.

ClpV recycles VipA/VipB tubules and prevents tubule formation to ensure efficient type VI protein secretion. [VipA, VipB, ClpV] (Mus musculus) PubMed

 11534.

OsCYP2 is involved in auxin signal transduction. It promotes degradation of AUX/IAA proteins and controls lateral root initiation. [CYP2] (Mus musculus) PubMed

 11535.

IDTR, which is dispensable for pneumococcal growth in vitro, is associated with regulation of pneumococcal virulence in specific host environments.[IDTR] (Mus musculus) PubMed

 11536.

A combination of comparative modeling, multiple molecular dynamics simulations and free energy calculation studies showed a difference in binding energies of native EhSAT3 and of a S208H-EhSAT3 mutant for cysteine.[EhSAT3] (Mus musculus) PubMed

 11537.

Radioimmunoassay experiments indicated that kinins can be generated by falcipain-2 and falcipain-3 proteolysis of high molecular weight kininogen.[falcipain-2 and falcipain-3] (Mus musculus) PubMed

 11538.

NDH2 is the major NADH : ubiquinone oxidoreductase responsible for cytosolic and not for mitochondrial NAD regeneration in the mitochondrion of procyclic T. brucei.[NDH2] (Mus musculus) PubMed

 11539.

The cyc gene is expressed in a circadian pattern in male Aedes brain. [cyc] (Mus musculus) PubMed

 11540.

Data indicate that DNA adenine methylase Dam regulated the expression of both RcsB and PmrA genes: [Dam, RcsB and PmrA] (Mus musculus) PubMed

 11541.

Study demonstrate that HAs from circulating clades require as few as a single base pair mutation to quantitatively switch their binding to human receptors.[HA] (Mus musculus) PubMed

 11542.

Study reports that the H7N9 HA shows limited binding to human receptors; however, should a single amino acid mutation occur, this would result in structural changes within the receptor binding site that allow for extensive binding to human receptors present in the upper respiratory tract.[H7N9 hemagglutinin] (Mus musculus) PubMed

 11543.

KaiB contacts the CII ring of KaiC.[KaiB, KaiC] (Mus musculus) PubMed

 11544.

this work underscores the role of the membrane and the transmembrane domain of TrwB in the T4SS function. [TrwB] (Mus musculus) PubMed

 11545.

The results suggest that PprA may play a crucial role in the control of DNA segregation and/or cell division after DNA double strand break repair (PprA). (Mus musculus) PubMed

 11546.

Leishmania MsrA contributes to the anti-oxidative defences.[MsrA] (Mus musculus) PubMed

 11547.

Two critical elements in the Tail domain of Pkl1 mediate gamma-tubulin small complex (gamma-TuSC) binding and trigger release of gamma-tubulin from gamma-TuRC.[Pkl1, gamma-tubulin] (Mus musculus) PubMed

 11548.

[endodeoxyribonuclease SgrAI] the collision cross section of the SgrAI-DNA oligomers is found to have a linear relationship with the number of DNA-bound dimers in each oligomer, suggesting a regular, repeating structure. (Mus musculus) PubMed

 11549.

The high resolution X-ray crystal structures of the unliganded form of Leishmania mexicana arginase (LmARG) and four inhibitor complexes are reported. [LmARG] (Mus musculus) PubMed

 11550.

These results revealed a pleiotropic regulatory role of RpoN in biofilm formation, production of proteases and exopolysaccharides, and virulence in Vibrio anguillarum M3.[RpoN] (Mus musculus) PubMed

 11551.

Rhcg1 and Rhbg mediate ammonia excretion by ionocytes and keratinocytes in the skin of zebrafish larvae.(Rhcg1 protein) (Mus musculus) PubMed

 11552.

The flagellar localization of FaaA differs markedly from the localization of other known autotransporters, and the current results reveal an important role of FaaA in flagellar localization and motility.[FaaA] (Mus musculus) PubMed

 11553.

The crystal structure of Thermotoga maritima NusG (TmNusG) shows a three-domain architecture, comprising well-conserved amino-terminal (NTD) and carboxy-terminal domains with an additional, species-specific domain inserted into the NTD. (Mus musculus) PubMed

 11554.

These results indicate that the N-terminal zinc finger motif of nsp1alpha plays an important role for type I interferon regulation via degradation of CREB-binding protein.[nsp1alpha] (Mus musculus) PubMed

 11555.

Data identify for the first time pp14 as a neurovirulence factor from MDV1 and open the possibility to investigate the molecular mechanisms by which pp14 mediates the damage to the avian nervous system.[pp14] (Mus musculus) PubMed

 11556.

CagA multimerization motifs motif patterns in the CagA 3'-variable region may be more significant than EPIYA motif patterns with respect to clinical outcomes. (Mus musculus) PubMed

 11557.

Data indicate that miR-21 is strongly expressed in the luminal cells of the normal mammary gland during early pregnancy, and that miR-205 and miR-200 are coexpressed but only during the second half of pregnancy: [miR-21, miR-205, and miR-200] (Mus musculus) PubMed

 11558.

When subjecting resting spores to 55 degrees C, an intact treB gene was essential for survival.[treB] (Mus musculus) PubMed

 11559.

This study reports characterization of a grape (Vitis vinifera) acyl-CoA-binding protein (VvACBP). Expression of VvACBP was detected in grape leaves exposed to tunicamycin-induced endoplasmic reticulum stress as well as cold and heat shock treatments. (Mus musculus) PubMed

 11560.

An ensemble of models for the solution structure of recombinant target recognition domain of zoocin A has been generated by NMR techniques. [zoocin A] (Mus musculus) PubMed

 11561.

identification of DNA polymerase alpha in yeast mitochondria [DNA polymerase alpha] (Mus musculus) PubMed

 11562.

These findings indicate that the 719th residue of arginine on E2 is critical to promote hepatitis C virus replication and infection.[E2] (Mus musculus) PubMed

 11563.

AvrPiz-t suppresses the ubiquitin ligase activity of the rice RING E3 ubiquitin ligase APIP6 and that, in return, APIP6 ubiquitinates AvrPiz-t in vitro. [APIP6] (Mus musculus) PubMed

 11564.

Protein K7 is a virulence factor that affects the acute immune response to infection. (Mus musculus) PubMed

 11565.

OsRab11 may be required for JA-mediated defense signaling by activating the reducing activity of OsOPR8 [Rab11] (Mus musculus) PubMed

 11566.

Data suggest that lymphocyte apoptosis in the cecal tonsil of broilers was mediated by direct effects of fluoride on the expression of Bcl-2, Bax, and caspase-3: [bax] (Mus musculus) PubMed

 11567.

Transgenic rice plants overexpressing OsTZF1 driven by a maize (Zea mays) ubiquitin promoter (Ubi:OsTZF1-OX [for overexpression]) exhibited delayed seed germination, growth retardation at the seedling stage, and delayed leaf senescence.[TZF1] (Mus musculus) PubMed

 11568.

FD function has diverged between OsFD1 and OsFD2, but formation of a hexameric florigen activation complex (FAC)is essential for their function. [OsFD1, OSFD2, OsFD3] (Mus musculus) PubMed

 11569.

In Salmonella typhi, Fur is a repressor of both sRNAs, and loss of either RfrA or RfrB resulted in distinct phenotypes, suggesting a non-redundant role for these regulatory RNAs.[Fur, RfrA, RfrB] (Mus musculus) PubMed

 11570.

These results strongly suggest that in the msrA mutant, glycerol is catabolized via the GlpK pathway, while in the msrB mutant, glycerol is metabolized via the DhaK pathway.[msrA, msrB] (Mus musculus) PubMed

 11571.

A cysteine in the repetitive domain of Bx7.1 glutenin subunit interferes with the mixing properties of wheat dough. [Bx7.1] (Mus musculus) PubMed

 11572.

Thus, although the p7 protein is functionally similar to the well-characterized influenza A virus M2 protein, they differ in their activation of autophagic cell-death.[p7] (Mus musculus) PubMed

 11573.

The influenza A virus PB2 MAVS-binding domain unexpectedly coincided with its PB1-binding domain, indicating an important dual functionality for this region of PB2.[PB1, PB2] (Mus musculus) PubMed

 11574.

PAN2 is at the top of a cascade of events promoting the polarization of subsidiary mother cell (SMC) divisions, potentially functioning to perceive or amplify guard mother cell (GMC)-derived polarizing cues. [PAN1 and PAN2] (Mus musculus) PubMed

 11575.

OsVIL2 (VIN3-LIKE 2) functions together with PRC2 to induce flowering by repressing OsLFL1.[VIL2;PRC2;LFL1] (Mus musculus) PubMed

 11576.

Collectively, the results presented here point at Trypanosoma cruzi PLA1 as a novel virulence factor implicated in parasite invasion.[PLA1] (Mus musculus) PubMed

 11577.

results suggest that PvDBPII of Korean P. vivax isolates display a limited genetic polymorphism and are under selective pressure[DBPII] (Mus musculus) PubMed

 11578.

hepatitis B virus e antigen; HBeAg) HBeAg induces the activation and proliferation of rat hepatic stellate cells (HSCs), mainly mediated by TGF-beta, and HBeAg protein purified from cell medium can directly activate HSCs. (Mus musculus) PubMed

 11579.

F. tularensis Schu S4 acid phosphatases, including the truncated HapA, play a major role in intramacrophage survival and virulence of this human pathogen [acpA] (Mus musculus) PubMed

 11580.

Quantification of A2 protein induced from a plasmid indicated that lysis is entrained when the amount of the lysis protein is approximately equimolar to that of cellular MurA.[A2] (Mus musculus) PubMed

 11581.

A novel rice storage glutelin subunit OsGluBX has been isolated and described. [OsGluBX] (Mus musculus) PubMed

 11582.

This putative prostanoid-like receptor, TcPR, is mainly localized in the flagellar membrane of the parasites and shows a similar glycosylation pattern to that of bona fide thromboxane prostanoid (TP) receptors obtained from human platelets.[TcPR] (Mus musculus) PubMed

 11583.

gea1 in regulation of septum breakdown and establish S. pombe as a model system to explore GBF1/GEA function in cytokinesis [Gea1] (Mus musculus) PubMed

 11584.

While ACAT1 preferentially utilizes palmitoyl-CoA, ACAT2 has broader fatty acid specificity. [ACAT2] (Mus musculus) PubMed

 11585.

The involvement of Lewis b and H type 1 structures of H. pylori in adhesion of bacteria to MUC1 mucin, was investigated.[Lewis b, Lewis H type 1] (Mus musculus) PubMed

 11586.

Authors determined crystal structures of RbmA and revealed that the protein folds into tandem fibronectin type III (FnIII) folds.[RbmA] (Mus musculus) PubMed

 11587.

Authors describe the contribution of Eep, a membrane-bound zinc metalloprotease, to the activation of SigV under lysozyme stress by its effects on the stability of the anti-sigma factor RsiV.[Eep, SigV, RsiV] (Mus musculus) PubMed

 11588.

The interaction of the cellular export adaptor protein Aly/REF with ICP27 contributes to the efficiency of herpes simplex virus 1 mRNA export. [ICP27] (Mus musculus) PubMed

 11589.

Authors conclude that in maize streak virus, RepA is necessary for single-stranded DNA production and efficient rolling circle replication.[RepA] (Mus musculus) PubMed

 11590.

These results indicate that capsid protein O-GlcNAcylation has a major role in the infection process.[capsid protein] (Mus musculus) PubMed

 11591.

In conclusion, AtlAEfm is the major autolysin in Enterococcus faecium and contributes to biofilm stability and Acm localization.[AtlA, Acm] (Mus musculus) PubMed

 11592.

In ku70 homologous recombination of URA3 marker at the ADE2 locus occurred with 43 % frequency with as little as 50 bp long flanking regions.[ku70] (Mus musculus) PubMed

 11593.

(COI1a and COI1b) Rice COI1a and COI1b complement Arabidopsis coi1-1 mutants by overexpression of either gene in the coi1-1 mutant, resulting in restoration of jasmonate signal transduction and seed production. (Mus musculus) PubMed

 11594.

Surprisingly, in vitro assays performed using recombinant forms of ZmpC indicated that the truncated ZmpC from strain SP168 induces more cleavage of the MUC16 ectodomain than its TIGR4 counterpart.[ZmpC] (Mus musculus) PubMed

 11595.

the primary role of Snapin in C. elegans [snapin] (Mus musculus) PubMed

 11596.

diverse CDI toxins are efficiently translocated across target cell envelopes [CdiA] (Mus musculus) PubMed

 11597.

A Serratia marcescens PigP homolog controls prodigiosin biosynthesis, swarming motility and hemolysis and is regulated by cAMP-CRP and HexS. [SmPigP] (Mus musculus) PubMed

 11598.

Hepatitis C virus NS5A protein caused down-regulation of mdr1 and up-regulation of bcrp expression in Huh7 cells.[NS5A] (Mus musculus) PubMed

 11599.

Reproductive organ and vascular specific promoter of the rice plasma membrane Ca2+ATPase mediates environmental stress responses in plants.[OsCa(2+)ATPase] (Mus musculus) PubMed

 11600.

Endo-1,4-beta-xylanase A (XynA) from Schizophyllum commune was cloned into pPCZalphaA and expressed in Pichia pastoris GS115. The open reading frame of the xynA gene is composed of 684 bp, encoding 278 amino acids with a molecular weight of 26 kDa. XYNA. (Mus musculus) PubMed

 11601.

Late maturity alpha-amylase is a consequence of a very narrow and transitory peak of expression of genes encoding high-isoelectric point alpha-amylase during grain development.[alpha amylase] (Mus musculus) PubMed

 11602.

ZmSNAC1 is a substrate of ZmOST1 [OST1] (Mus musculus) PubMed

 11603.

Parasites harboring PfRH5 polymorphisms 204K or 204R are also able to invade rat erythrocytes and are differentially sensitive to the removal of surface sialic acids by neuraminidase.[PfRH5] (Mus musculus) PubMed

 11604.

PfATP4 is postulated to be a Na+ efflux ATPase and a target of the spiroindolones. [ATP4] (Mus musculus) PubMed

 11605.

The dextransucrase was stable up to 35 degrees C and pH of 5.4 for 1 hr. The enzyme followed Michaelis-Menten kinetics with Km of 13 mM and Vmax 27.5 U/mg.[dextransucrase] (Mus musculus) PubMed

 11606.

a new cellobiose-responsive PTS operon, together with its transcriptional regulator in S. pneumoniae [BguR] (Mus musculus) PubMed

 11607.

Xanthomonas effector XopD suppresses ethylene-stimulated immunity of tomato leaf infection. [XopD] (Mus musculus) PubMed

 11608.

Biochemical and genetic analyses proved that sigma(ShbA) is a major determinant of transcription of the sigma(HrdB) gene.[ShbA, HrdB] (Mus musculus) PubMed

 11609.

This is the first report analyzing the phosphorylation of AspE and localizing the sites of phosphorylation, and opens opportunities for further analysis on the role of post-translational modifications in the assembly and organization of A. fumigatus septins.[AspE] (Mus musculus) PubMed

 11610.

These results suggested Bursal-derived biological active factor BPP-II might be involved in the antibody production processes and B cell development, which is vital to the humoral central immune organ, the bursa of Fabricius.[BPP-II] (Mus musculus) PubMed

 11611.

The inactivation of ibeB resulted in reduced invasion capacity towards DF-1 cells and defective virulence in animal models as compared to the wild-type strain; These results indicate that IbeB is involved in APEC invasion and pathogenicity.[IbeE] (Mus musculus) PubMed

 11612.

These results suggested that the single gene either iucB or iutA was likely to be involved directly or indirectly in iron uptake for the pathogenicity of APEC E058, and there was an obviously synergistic effect between iucB and iutA genes on the pathogenicity of APEC E058.[iucB, iutA] (Mus musculus) PubMed

 11613.

The study used continuum solvation binding affinity predictions and graph theory-based flexibility calculations to model thirteen drug resistance mutations in HCV NS3/4A serine protease, against three small-molecule inhibitors. [NS3/4A serine protease] (Mus musculus) PubMed

 11614.

the requirement for the Leader protein coding sequences for virus replication is highly dependent on the nature and extent of the residual Leader protein sequences and on the host cell system used. [leader protein] (Mus musculus) PubMed

 11615.

ManR, a transcriptional regulator of the beta-mannan utilization system, controls the cellulose utilization system in Aspergillus oryzae. [ManR] (Mus musculus) PubMed

 11616.

This experiment was designed to determine if differences in allelic frequency of the myostatin (MSTN) g+6723G>A mutation affected abundance of myostatin protein from birth to 24 wk of age.[MSTN] (Mus musculus) PubMed

 11617.

The absence of ARSA1 in as1 mutant leads to a small chloroplast and a strongly decreased chlorophyll content per cell. ARSA1 appears to be required for optimal biogenesis of photosynthetic complexes because of its involvement in the accumulation of TOC34 (ARSA1). (Mus musculus) PubMed

 11618.

Two transcription factors (TFs), NSP2 and bHLH476, are direct cytokinin targets acting at the convergence of phytohormonal and symbiotic cues. [bHLH476] (Mus musculus) PubMed

 11619.

OsAIP1 acts coordinately with ADF and profilin to induce massive net actin depolymerization, indicating that AIP1 plays a major role in the turnover of actin, which is required to optimize F-actin levels in plants. [OsAIP1] (Mus musculus) PubMed

 11620.

SUB1A-1 is not essential to confer submergence tolerance in the wild rice genotypes belonging to the C-genome group, which show instead a SUB1A-independent response to submergence. (Mus musculus) PubMed

 11621.

HVR-1 genetic changes manifested by new SSCP bands (new genetic variants) were significantly more frequent in nonresponders (P <0.05) during the early phase of pegylated interferon and ribavirin therapy. (HVR-1) (Mus musculus) PubMed

 11622.

HDT701 negatively regulates innate immunity by modulating the levels of histone H4 acetylation of PRR and defense-related genes in rice [HDT701] (Mus musculus) PubMed

 11623.

Os-YSL16 is a Cu-nicotianamine transporter that is required for delivering Cu to the developing young tissues and seeds through phloem transport. [Os-YSL16] (Mus musculus) PubMed

 11624.

Phospholipid:diacylglycerol acyltransferase (PDAT) is a multifunctional protein and plays an essential role in membrane turnover, degradation, and triacylglycerols (TAGs)formation in Chlamydomonas reinhardtii. (Mus musculus) PubMed

 11625.

The rabies virus interferon antagonist P protein interacts with activated STAT3 and inhibits Gp130 receptor signaling. (Mus musculus) PubMed

 11626.

findings show that Caudal acts as a negative regulator in the Imd pathway-mediated immune response against the human malaria parasite Plasmodium falciparum [Caudal] (Mus musculus) PubMed

 11627.

Data indicates that sodium solute symporter (TcSSS; TcasGA2_TC013040 EFA03129) is a putative Cry3Ba toxin-binding protein [TcSSS]. (Mus musculus) PubMed

 11628.

Xanthomonas campestris pv. vesicatoria effector AvrBsT overexpression triggers plant cell death, disease and defense signaling leading to both disease and defense responses to microbial pathogens of different lifestyles. [AvrBsT] (Mus musculus) PubMed

 11629.

Osj10gBTF3 plays an important role in rice growth and development. [Osj10gBTF3] (Mus musculus) PubMed

 11630.

we report the cloning and expression of the rice bran lipase in Escherichia coli and Pichia pastoris (Mus musculus) PubMed

 11631.

Consequently, FATP1 deficiency prevented the differentiation while induced apoptosis in chicken preadipocytes (Mus musculus) PubMed

 11632.

The structure of F-ATPase from Saccharomyces cerevisiae inhibited by the yeast IF has been determined at 2.5 A (Mus musculus) PubMed

 11633.

In Ciona notochord, tubulogenesis occurs in a single file of cells in the absence of cell proliferation; at the molecular level, cells establish two discrete Par3/Par6/aPKC patches, and form two sets of tight junctions, in opposite points of the cells. The key molecule controlling the formation of both domains is Par3. [Par3] (Mus musculus) PubMed

 11634.

PMT1 gene disrupted Pichia clone showed approximately 60% decrease in O-mannosylated insulin precursor, establishing its role as an important enzyme for insulin precursor O-mannosylation. (Mus musculus) PubMed

 11635.

overexpression of rice proteins OsRecQl4 (BLM counterpart) and/or OsExo1 (Exo1 homolog) can enhance DNA double-strand break (DSB) processing, as evaluated by recombination substrate reporter lines in rice. [OsRecQl4] (Mus musculus) PubMed

 11636.

NS3 of bluetongue virus interferes with the induction of type I interferon. [NS3] (Mus musculus) PubMed

 11637.

TaAQP8 confers salt stress tolerance not only by retaining high a K(+)/Na(+) ratio and Ca(2+) content, but also by reducing H(2)O(2) accumulation and membrane damage by enhancing the antioxidant system. [TaAQP8] (Mus musculus) PubMed

 11638.

m131/129 (also known as MCK-2) enhances alpha interferon production by plasmacytoid dendritic cells but delays CD8+ T cell activation and impairs viral clearance. (Mus musculus) PubMed

 11639.

It will be essential to suppress BmASNS expression by PcG proteins at the G2/M phase of the cell cycle in the presence of BmC/ebp activator. (Mus musculus) PubMed

 11640.

Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase. [octaprenyl pyrophosphate synthase] (Mus musculus) PubMed

 11641.

The X-ray crystal structure of ribosome hibernation promoting factor (HPF) from Vibrio cholerae is presented at 2.0 A resolution. (Mus musculus) PubMed

 11642.

the expression, purification, crystallization and preliminary crystallographic analysis of SpDnaJ are reported. [DnaJ] (Mus musculus) PubMed

 11643.

beta-Mannosidase was crystallized and the crystal diffracted to 2.41 A resolution. The parameters derived from the data collection indicate the presence of one molecule in the asymmetric unit. (Mus musculus) PubMed

 11644.

A gene involved in sperm activation, spe-46, is reported.[Spe-46] (Mus musculus) PubMed

 11645.

OsCHR4, the rice Mi-2-like protein, plays an important role in early chloroplast development in adaxial mesophyll cells. [OsCHR4] (Mus musculus) PubMed

 11646.

This work reports the biochemical and functional analysis of the Burkholderia cenocepacia J2315 bceN gene, encoding a protein with GDP-D-mannose 4,6-dehydratase enzyme activity.[bceN] (Mus musculus) PubMed

 11647.

IPSE may influence the polarity of immune responses during xenograft rejection and suppress Th1 responses. This parasitic immune evasion mechanism could help in overcoming xenograft rejection. (IL-4-inducing principle of Schistosoma mansoni eggs, IPSE) (Mus musculus) PubMed

 11648.

The cDNA sequence was similar to those of several fish viperins in GenBank, and it was predicted to encode the conserved domain of radical S-adenosylmethionine superfamily proteins. (viperin) (Mus musculus) PubMed

 11649.

The crystal structure of the Golgi casein kinase Fam20C ortholog is reported. The nucleotide-free and Mn/ADP-bound structures unveil an atypical protein kinase-like fold and highlight residues critical for activity. (Fam20) (Mus musculus) PubMed

 11650.

Water flow through KcsA is halved by 200 mM K+ in the aqueous solution, which indicates an effective K+ dissociation constant in that range for a singly occupied channel. (KcsA) (Mus musculus) PubMed

 11651.

A 2-on-2 ("truncated") hemoglobin termed THB8 is required for hypoxic growth and the expression of anaerobic genes (THB8) (Mus musculus) PubMed

 11652.

The results suggest that PaaT is involved in penicillin production, most likely through the translocation of side-chain precursors (phenylacetic acid and phenoxyacetic acid) from the cytosol to the peroxisomal lumen across the peroxisomal membrane.[PaaT] (Mus musculus) PubMed

 11653.

XB25 is required for maintaining XA21-mediated disease resistance. [XA21 and XB25] (Mus musculus) PubMed

 11654.

Ag5-like gene is expressed by venom gland tissue of winter bees but not of summer bees. Besides this seasonal variation, it shows expression pattern with additional production in the hypopharyngeal glands, the brains and the midgut.[Ag5-like gene] (Mus musculus) PubMed

 11655.

PABP1 and PABP2 exhibit major differences in intracellular localization and distribution on polysome fractionation under various conditions that interfere with mRNA metabolism (Mus musculus) PubMed

 11656.

study reports functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter; direct involvement of Msr(D) in the efflux of macrolides remains to be demonstrated [Msr(D),Mef(E)] (Mus musculus) PubMed

 11657.

Unprocessed YedY-A44L is membrane-bound with the mature protein exposed to the periplasm in Escherichia coli. [YedY] (Mus musculus) PubMed

 11658.

L-asparaginase II (ansB) permits growth on asparagine and glycerol under anaerobic conditions. [ansB] (Mus musculus) PubMed

 11659.

TF promotes correct folding by protecting partially folded states from distant interactions that produce stable misfolded states [Trigger Factor] (Mus musculus) PubMed

 11660.

Analysis of RNA binding to Hera identifies residues important for high-affinity RNA binding (Hera). (Mus musculus) PubMed

 11661.

In the presence of >/=1 muM SlyD, protein molecules with cis and trans prolyl isomers refold with identical rates, because SlyD-catalyzed cis/trans equilibration is faster than conformational folding.[SlyD] (Mus musculus) PubMed

 11662.

We concluded that class VI chitin synthase could be essential for B. cinerea and therefore BcCHS6 represents a valuable antifungal target. (Mus musculus) PubMed

 11663.

Data indicate that Salmonella typhi OmpS1 and OmpS2 are potent protective immunogens with intrinsic adjuvant properties. (Mus musculus) PubMed

 11664.

Our data suggest that the non-protein coding locus Mcs1a regulates Nr2f1, which is a candidate modifier of differentiation, proliferation, and mammary cancer risk (Mus musculus) PubMed

 11665.

inhibitor-bound crystal structures of AcrB and MexB, in which these proteins are bound by a pyridopyrimidine derivative [AcrB] (Mus musculus) PubMed

 11666.

Short chained lipids promote EmrE protein stringing. Longer lipids promote EmrE protein clusters. [EmrE] (Mus musculus) PubMed

 11667.

The study reports a single-molecule Forster resonance energy transfer system that directly monitors the movement of a DNA substrate between the pol and exo sites of DNA polymerase I Klenow fragment. [Klenow fragment] (Mus musculus) PubMed

 11668.

The cytoplasmic male sterile protein, ORFH79, can bind to complex III and decrease its enzyme activity through interaction with P61.[ORFH79, P61] (Mus musculus) PubMed

 11669.

EtCDPK3 may be involved in invasion and survival of the parasite intracellular stages of Eimeria tenella. [EtCDPK3] (Mus musculus) PubMed

 11670.

whole-transcriptome analysis suggested that BcYOH1 might act as a global transcriptional regulator of phytotoxin and other secondary metabolism gene clusters (Mus musculus) PubMed

 11671.

MVA lacking IL-1beta receptor leads to increased concentrations of free IL-1beta upon infection of murine and human antigen presenting cells.[IL-1beta receptor] (Mus musculus) PubMed

 11672.

Light activation of AppA-PpsR2 affects the PpsR effector region within the complex. DNA binding shows the formation of a light-sensitive ternary AppA-PpsR-DNA complex (AppA and PpsR). (Mus musculus) PubMed

 11673.

Mip-r1, mip-r2 and sifa-r and their ligands control of the function of salivary glands.[Mip-r1, mip-r2 and sifa-r] (Mus musculus) PubMed

 11674.

Molecular characterization of the LTR, env, and tax regions of 38 isolates confirmed the HTLV-2c variant in 37 patients. (tax protein, env protein) (Mus musculus) PubMed

 11675.

Abiotic stress initiates the Mitochondrial retrograde regulation (MRR)on OsAOX1a/b and that mitochondrial O2.(-) is involved in the process. [OsAOX1a, OsAOX1b] (Mus musculus) PubMed

 11676.

crystallographic structure of 5-Chloromuconolactone dehalogenase (5-CMLD)was solved and refined at 2.2 A of resolution and molecular docking calculations were performed, which allowed confirmation of active site localization and identification of the residues involved in substrate binding and catalysis (5-CMLD) (Mus musculus) PubMed

 11677.

The GIIalpha gene (GenBank: AB749778) consisted of 2778 bp encoding a protein of 925 amino acids with a predicted molecular mass of 104,633 Da. [GIIalpha] (Mus musculus) PubMed

 11678.

Authors report a complete model of the extra-membrane domain of the V-ATPase (V1-ATPase) of a thermophilic bacterium, Thermus thermophilus, consisting of three A subunits, three B subunits, one D subunit, and one F subunit.[V1-ATPase] (Mus musculus) PubMed

 11679.

The purified TreS enzyme had an optimum temperature of 25 degrees C and pH optimum around 7.0. [TreS] (Mus musculus) PubMed

 11680.

SP-D participates in host defense against the vaccinia virus infection by interaction with the viral surface protein A27. [A27] (Mus musculus) PubMed

 11681.

Cj0045 are strongly associated with mouse colonization. [Cj0045] (Mus musculus) PubMed

 11682.

S. aureus RNase III cleaves regular RNA-RNA helices and RNA hairpins in a similar manner.[RNaseIII] (Mus musculus) PubMed

 11683.

Here we describe a new gene, LF5, in which null mutations cause cells to assemble flagella of excess length (Mus musculus) PubMed

 11684.

Results identified akirin (akir-1) as a gene involved in key events of meiotic prophase I: [akir-1] (Mus musculus) PubMed

 11685.

The importance of TALE1(Xam) in the pathogenicity of Xanthomonas axonopodis pv. manihotis, is demonstrated.[TALE1] (Mus musculus) PubMed

 11686.

FgERG4 plays a crucial role in ergosterol biosynthesis, vegetative differentiation and virulence in the filamentous fungus F. graminearum.[FgERG4] (Mus musculus) PubMed

 11687.

These results highlight the functions of the BaeSR regulon in metal homeostasis.[BaeR, BaeS] (Mus musculus) PubMed

 11688.

Sister chromatid separation in oocytes depends on a PP2A inhibitor, namely I2PP2A. In oocytes I2PP2A is essential for faithful sister chromatid segregation by mediating deprotection of centromeric cohesin in meiosis II.[I2PP2A] (Mus musculus) PubMed

 11689.

Together these results indicate that xenotropic Murine leukemia virus-Related Virus envelope proteins are sufficient to induce the production of factors by tumor cells that suppress vascular smooth muscle cell differentiation.[env] (Mus musculus) PubMed

 11690.

The SURFIN4.1 transmembrane region is essential for the initial recruitment of the protein to the ER, and the following sorting step to the parasitophorous vacuole is determined by two signals located in the N-terminus 50 amino acids. [SURFIN4.1] (Mus musculus) PubMed

 11691.

Taken together, these results suggest that nonsexual flocculation in fission yeast is negatively controlled by Gsf1, which controls expression of mbx2(+) and gsf2(+).[Gsf1, gsf2, mbx2] (Mus musculus) PubMed

 11692.

we demonstrate that PI4KIIIalpha activity affects the nonstructural protein 5A (NS5A) phosphorylation status in hepatitis C virus (Mus musculus) PubMed

 11693.

HIV-2 capsid sequences expressed high levels of susceptibility to hTRIM5alpha. (Mus musculus) PubMed

 11694.

Examined 44 BLV isolates from different geographical regions of Poland, Belarus, Ukraine, and Russia. Phylogenetic analysis based on a 444bp fragment of env gene revealed that most of isolates belonged to genotypes 4 and 7. (env) (Mus musculus) PubMed

 11695.

Functional characterization of a Bs-group MADS-box gene FEMALE-STERILE (FST), whose frame-shift mutation (fst) results in abnormal ovules and the complete abortion of zygotic embryos and endosperms. (FST) (Mus musculus) PubMed

 11696.

We conclude that Plasmodium berghei thrombospondin-related adhesive protein is an immunodominant antigen during liver-stage infection. (Mus musculus) PubMed

 11697.

we demonstrate that T. annulata p104, a polymorphic antigen expressed on the schizont surface, functions as a genuine EB1-binding protein and can recruit EB1 in the absence of any other parasite proteins. (Mus musculus) PubMed

 11698.

NleF, binds to caspase-4, -8, and -9 and inhibits the catalytic activity of the caspases [NleF] (Mus musculus) PubMed

 11699.

This study indicates a critical role for gacA in the efficient utilization of specific components of coral mucus and establishment within the surface mucopolysaccharide layer (gacA). (Mus musculus) PubMed

 11700.

LAMMER kinase is involved in A. nidulans development by modulating the expression of key regulators of developmental processes (Mus musculus) PubMed

 11701.

the full-length cDNA of the BAFF gene, designated xlBAFF, from the X. laevis was cloned. [xiBAFF] (Mus musculus) PubMed

 11702.

Rice nonsymbiotic hemoglobin 1 crystallizes as a fully associated homodimer with both subunits in 6c state, but showing slightly different conformations, thus leading to an asymmetric crystallographic homodimer.[nonsymbiotic hemoglobin 1] (Mus musculus) PubMed

 11703.

calcineurin and Kin1 activities must be tightly coordinated to link actomyosin ring assembly with septum synthesis.[Calcineurin, Kin1] (Mus musculus) PubMed

 11704.

toxT transcription is regulated by either acetyl-CoA or some close derivative. [ToxT] (Mus musculus) PubMed

 11705.

These data indicate that, while hysA message levels and hyaluronidase activity are elevated, the increase in activity did not contribute to the biofilm-negative phenotype observed in the sarA mutant strain of S. aureus UAMS-1. [sarA, hysA] (Mus musculus) PubMed

 11706.

Our study shows that ompW is upregulated in response to menadione in a cooperative manner by MarA and SoxS through a direct interaction with the promoter region.[OmpW. marA,soxS] (Mus musculus) PubMed

 11707.

optimal NatA function is important to the cooperative function of Brx1 with Ebp2 in 60S ribosomal subunit biogenesis (Mus musculus) PubMed

 11708.

Bmgr5 quantitative trait locus has been divided into two separate subloci, termed Bmgr5a and Bmgr5b, each conferring permissiveness for the engraftment phenotype.[Bmgr5a;Bmgr5b] (Mus musculus) PubMed

 11709.

Opn4 gene was 1 437 bp in length which encodes 478 amino acids residues. [opn4] (Mus musculus) PubMed

 11710.

In this study, use of high-throughput Phenotype microarray screening in conjunction with minimal media testing has highlighted differences in carbon utilization in wild-type and CRP mutant strains of V. cholerae. Eleven of the 24 CRP-regulated carbon sources identified in this study have not been previously reported.[cAMP receptor protein] (Mus musculus) PubMed

 11711.

These results demonstrate that glycosylation patterns of the 1918 and seasonal H1N1 viruses directly contribute to differences in virulence and are partially responsible for their distinct antigenicity. (Mus musculus) PubMed

 11712.

Kaposin B significantly contributes to the chronic inflammatory environment by unique activation of the proto-oncogene STAT3, coupled with MK2-mediated inactivation of the STAT3 transcriptional repressor TRIM28.[Kaposin B] (Mus musculus) PubMed

 11713.

Mutation of either the predicted catalytic serine or histidine inactivated mature gp175, supporting its classification as a serine protease.[gp175] (Mus musculus) PubMed

 11714.

Authors conclude that Brucella BioR is not only a negative autoregulator but also a repressor of expression of bioY and bio operons that separately function in biotin transport and the biosynthesis pathway.[BioR] (Mus musculus) PubMed

 11715.

Data suggest that ischemia/reperfusion (I/R) injury promotes NF-kappaappaB p65 activity, in response to reactive oxygen species (ROS) to aggravate myocardial injury through the activation of Beclin 1-mediated autophagy; [NF-kappaB p65 and Beclin 1] (Mus musculus) PubMed

 11716.

SubAB may directly participate in the mechanisms of diarrhea in children infected with non-O157 STEC strains[subA and sub B] (Mus musculus) PubMed

 11717.

An mgtC null mutant displays heightened ATP levels and an acidic cytoplasm, whereas mgtC overexpression decreases ATP levels. A single amino acid substitution in MgtC that prevents binding to the F1Fo ATP synthase abolishes control of ATP levels and attenuates pathogenicity. [MgtC,F1F0Atpase] (Mus musculus) PubMed

 11718.

The results suggest that H. pylori strains with Thr70-type NapA have enhanced Fe ion uptake ability and are associated with the pathogenesis of iron deficiency anemia (NapA). (Mus musculus) PubMed

 11719.

Cyanobacterial SsAqpZ may exert a pleiotropic function in addition to the already reported roles in macronutrient homeostasis and osmotic-stress response.[SsAqpZ] (Mus musculus) PubMed

 11720.

Data indicate that in comparison with the NS88.2 wild type, both NS88.2DeltasclA and NS88.2Deltagls24 displayed significantly reduced neutrophil resistance: [sclA and gls24] (Mus musculus) PubMed

 11721.

These results suggest that natural variation in the heparan sulfate binding domain of E2 glycoprotein may arise during sylvatic cycles of the virus and that this variation may influence receptor interaction and the severity of disease.[E2 glycoprotein] (Mus musculus) PubMed

 11722.

RLCK185(Os05g0372100) is targeted by Xanthomonas oryzae effector is directly phosphorylated by the CERK1 and mediates rice immunity.[CERK1] (Mus musculus) PubMed

 11723.

ARO mediates the apical positioning of rhoptry organelles, a prerequisite for host cell invasion. [ARO] (Mus musculus) PubMed

 11724.

SWAP-70 is not required for podosome formation and F-actin turnover in dendritic cells.[F-actin] (Mus musculus) PubMed

 11725.

These results demonstrate not only a critical function of an N-terminal PFV Gag motif for the essential capsid - glycoprotein interaction required for virus budding but also point out additional functions that affect virion infectivity.[Gag, Env] (Mus musculus) PubMed

 11726.

The effect of ssRNA on the ATPase activity of NS3 was studied using poly(A) and poly(C). Both RNA molecules produced a 10 fold increase in the turnover rate constant and a 100 fold decrease in the apparent affinity for ATP. (NS3) (Mus musculus) PubMed

 11727.

Expression and subcellular localization of the PbMAPK1 protein in liver stage parasites, were investigated.[MAPK1] (Mus musculus) PubMed

 11728.

SipC binds SipB through its C-terminal region to facilitate membrane-insertion and subsequent translocon formation in the host cell membrane.[SipB, SipC] (Mus musculus) PubMed

 11729.

This result was consistent with the effect of phosphine on algal growth, while TpPHO expression and AKP were even more sensitive to phosphine than algal growth.[TpPHO, AKP] (Mus musculus) PubMed

 11730.

The porB gene of strain IU824, however, was found to contain a premature stop codon not previously identified, which is noteworthy but unlikely to be related to tetracycline resistance. [PorB] (Mus musculus) PubMed

 11731.

This report sheds light on the differential regulation of CgRTA1 and CgRSB1 in C. glabrata. [CgRTA1 and CgRSB1] (Mus musculus) PubMed

 11732.

an individual cell motility assay showed that the population of DeltarpoS cells had bimodal motility character, and that a minority of this population exhibited a much higher motility rate [rpoS] (Mus musculus) PubMed

 11733.

Fluoroquinolone genes qnrA and qnrB were detected among representative fluoroquinolone-resistant isolates of commensal E coli that were recovered from the feces of apparently healthy cattle.[qnrA and qnrB] (Mus musculus) PubMed

 11734.

In this work, we demonstrate that mutations in migR, trmE, or cphA significantly reduce ppGpp accumulation (Mus musculus) PubMed

 11735.

Under iron-limiting conditions, Fur fails to bind either region and the expression of smcR is regulated solely by quorum sensing[SmcR] (Mus musculus) PubMed

 11736.

These results show that changes in the transmembrane domain of SIVcpzPtt, SIVcpzPts and SIVgor Vpus are sufficient to render them active against human tetherin.[Vpu] (Mus musculus) PubMed

 11737.

The loss-of-function Hd5 was introduced into the rice variety Fanny from France and contributed to its extremely early heading under the presence of functional Ghd7. [Hd5] (Mus musculus) PubMed

 11738.

CstR is readily modified by selenite (SeO3(2-)) or tellurite (TeO3(2-)) to form a mixture of intersubunit disulfides and selenotrisulfides or tellurotrisulfides, respectively, between Cys31 and Cys60'.[CstR] (Mus musculus) PubMed

 11739.

The results indicate that Red5 function is important to meiotic mRNA degradation (Red5). (Mus musculus) PubMed

 11740.

These findings suggest that the direct contact of Dengue virus 2 E protein with 43 kDa actin protein may have a crucial function in Dengue virus 2 infection of ECV304 cells.[E glycoprotein] (Mus musculus) PubMed

 11741.

Significant expression of FGF23 and KL within the growth plate and adjacent tissues imply a potential local role of FGF23 in chondrocyte differentiation and tissue mineralization.[FGF23] (Mus musculus) PubMed

 11742.

C. jejuni TsdA is a bifunctional tetrathionate reductase/thiosulphate dehydrogenase with a high affinity for tetrathionate.[TsdA] (Mus musculus) PubMed

 11743.

The conserved active site structures of ClcF (chloromuconolactone dehalogenase) suggest that the catalytic mechanism is representative for the MLI family and ClcF is a novel type of dehalogenase based on an isomerase scaffold. [ClcF] (Mus musculus) PubMed

 11744.

*Drug Discovery *Computer Simulation Algorithms The F-box protein MEC-15 (FBXW9) promotes synaptic transmission in GABAergic motor neurons in C. elegans. (Mus musculus) PubMed

 11745.

[Nsp2] Nsp2 plays a positive role in PRRSV proliferation (Mus musculus) PubMed

 11746.

results indicate that precise control of SNAP-25 expression by miR-153 is critically important for proper neuronal patterning as well as neurotransmission [microrna-153] (Mus musculus) PubMed

 11747.

enzyme cooperativeness was kept intact by at least two residues, Glu89 and His465, of which Glu89 is newly identified to be involved in the cooperativity system of GAD [GADbeta] (Mus musculus) PubMed

 11748.

Crystal structure and biochemical analysis of Histidine-containing phosphotransfer protein 1 from Medicago truncatula. (Mus musculus) PubMed

 11749.

Genetic diversity and lack of artemisinin selection signature have been found on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion. [PfATP6] (Mus musculus) PubMed

 11750.

Improved functions of protein complexes in the thylakoid membrane in tasg1 facilitate photosynthesis and drought resistance. [tasg1] (Mus musculus) PubMed

 11751.

BcSpl1 is also able to induce in tobacco systemic resistance to two plant pathogens, Pseudomonas syringae and B. cinerea, which correlates with the induction of two pathogenesis-related genes.[BcSpl1] (Mus musculus) PubMed

 11752.

Inositol-trisphosphate 3-kinase B (Itpkb) via its enzymatic product inositol 1,3,4,5-tetrakisphosphate (InsP4) plays an essential role during wound healing by modulating the activity of Rho family GTPases and F-actin ring assembly. (Itpkb) (Mus musculus) PubMed

 11753.

A model in which MuB-imposed symmetry transiently deforms the DNA at the boundary of the MuB filament and results in a bent DNA favored by MuA for transposition (MuB) (Mus musculus) PubMed

 11754.

(telomerase) The NMR structure of the telomerase RNA (TER) pseudoknot reveals that it contains a long pyrimidine motif triple helix with unexpected features: 3 individual bulge nucleotides and a C(+)*G-C triple adjacent to a stem 2-loop 2 junction. (Mus musculus) PubMed

 11755.

The gamma-glutamyl cycle and glutathione biosynthesis are subject to regulation by Snx41-dependent vesicular trafficking, and mediate antioxidant defense crucial for in planta growth and pathogenic differentiation of Magnaporthe.[Snx41] (Mus musculus) PubMed

 11756.

Data indicate that pantothenate tranorter PfPAT (PF3D7_0206200) plays an essential function in parasite development and thus is a valid target for antimalarial therapy[PfPAT] (Mus musculus) PubMed

 11757.

Results established Sre2 as a model to define structural requirements for sterol regulatory element-binding protein (SREBP) cleavage [Sre2] (Mus musculus) PubMed

 11758.

Interferon induction-suppressing particles activity was dependent solely on the expression of the NS gene.[NS1] (Mus musculus) PubMed

 11759.

MapP (maltose 6'-phosphate phosphatase)connects PTS-mediated maltose uptake to maltose phosphorylase-catalysed metabolism. [MapP] (Mus musculus) PubMed

 11760.

A single arrestin-like protein, ArtA, is essential for HulA(Rsp) (5) -dependent ubiquitination and endocytosis of UapA in response to ammonium or substrates.[ArtA, UaspA]. (Mus musculus) PubMed

 11761.

Data indicate that terminal uridylyl transferase XTUT7 contains a nucleic acid-binding domain important for activity and can repress translation [XTUT7] (Mus musculus) PubMed

 11762.

Study shows that Rep1 stability is reduced in the absence of Rep2, and that both Rep proteins are sumoylated. Lysine-to-arginine substitutions in Rep1 and Rep2 that inhibited their sumoylation perturbed plasmid inheritance without affecting Rep protein stability or 2-hybrid interaction between Rep1 and Rep2. [Rep1, Rep2] (Mus musculus) PubMed

 11763.

Caulobacter crescentus cells lacking the CcrM enzyme accumulate low levels of the two conserved FtsZ and MipZ proteins, leading to a severe defect in cell division.[CcrM, FtsZ, MipZ] (Mus musculus) PubMed

 11764.

TnpB appears to play a regulatory role in ISDra2 transposition. (Mus musculus) PubMed

 11765.

Sterol uptake in C. glabrata is mediated by Aus1p alone and can occur in iron poor environment of host tissues or following azole administration and thus may contribute to C. glabrata pathogenesis. [Aus1p] (Mus musculus) PubMed

 11766.

PiGK4 (G-protein-coupled receptor with a phosphatidylinositol phosphate kinase domain is not only involved in spore germination and hyphal elongation but also in sporangia cleavage and infection. [PiGK4] (Mus musculus) PubMed

 11767.

T7 RNA polymerase-promoter complexes were characterized by means of fluorescence spectroscopy and differential scanning calorimetry.[Rna polymerase] (Mus musculus) PubMed

 11768.

The model of the Leishmania donovani GAPDH exhibited NAD-binding domain with Rossmann folding.[GAPDH] (Mus musculus) PubMed

 11769.

the evolutionary characterization of the TAC1 gene [TAC1] (Mus musculus) PubMed

 11770.

A homologue for a chicken novel gene was described. The chicken melanoma differentiation associated gene-9 (mda-9) gene was found to be expressed in many tissues and cell lines and the effect of lipopolysaccharide stimulation was investigated. [mda-9] (Mus musculus) PubMed

 11771.

Study identified the mechanism that maintains presynaptic distribution during postdevelopmental growth; the requirement of a SLC17 family transporter CIMA-1. CIMA-1 antagonizes a specific FGFR isoform, EGL-15(5A), in epidermal cells to modulate glial morphology, in turn modulating AIY synaptic distribution.[cima-1- locus F45E4.11 (discontinued)] (Mus musculus) PubMed

 11772.

evolution of context-dependent differences in the nature of genetic redundancy, and function, between hcpG and hcpC may facilitate their maintenance in H. pylori genomes, and confer robustness to H. pylori growth during infection (Mus musculus) PubMed

 11773.

DinB is specific for bypass of minor groove adducts and it is specifically inhibited by major groove DNA modifications. [DinB] (Mus musculus) PubMed

 11774.

Together, our results suggest a model in which the N-terminal portion of ICP27 mediates a nonessential activity that interferes with HSV-1 replication when CRM1 is inactive. (Mus musculus) PubMed

 11775.

The virion host shutoff (VHS) protein plays an important roles in regulating innate antiviral responses against HSV-2 from primary genital epithelial cells. [VHS] (Mus musculus) PubMed

 11776.

Dengue virus infection of Huh 7 cells decreased the mRNA levels of host RNAi factors, namely, Dicer, Drosha, Ago1, and Ago2, and in corollary, silencing of these genes in virus-infected cells enhanced dengue virus replication.[NS4B] (Mus musculus) PubMed

 11777.

observations indicate that high Trx1 expression in H. pylori is associated with gastric carcinogenesis [Trx1] (Mus musculus) PubMed

 11778.

These results support a model in which the N-nsp3 interaction serves to tether the genome to the newly translated replicase-transcriptase complex at a very early stage of infection.[nsp3] (Mus musculus) PubMed

 11779.

Self-processing inactivates leader proteinase nsp1alpha of Porcine reproductive and respiratory syndrome virus but not Lb(leader proteinase) of FMDV. [Lb] (Mus musculus) PubMed

 11780.

This study used both field and laboratory assays to study the influence of the Mv gene of corn on the life history of the corn planthopper P. maidis and on the transmission of maize streak virus. [Mv protein] (Mus musculus) PubMed

 11781.

This study indicates that cytomegaloviruses use a conserved mechanism to promote transcription at late stages of infection and that pM79 is a critical regulator for at least a subset of viral DNA synthesis-dependent transcripts.[pM79] (Mus musculus) PubMed

 11782.

This study showed the Skp plays a role in LptD assemply, but that this role can be performed by FkpA.[Skp; LptD] (Mus musculus) PubMed

 11783.

This study shows that both ppGpp and FadR have direct roles in the control of fatty acid promoters, linking expression in response to both translation activity and fatty acid availability. (Mus musculus) PubMed

 11784.

alpha-hemolysin-induced platelet-neutrophil aggregate formation was solely platelet P-selectin dependent.[alpha-hemolysin] (Mus musculus) PubMed

 11785.

Interaction between OsDRM2 and OseIF4A is specifically mediated through ubiquitin-associated domain of OsDRM2 while, both domains 1 and 2 of OseIF4A are critical for mediating strong interaction with OsDRM2 in vivo.[DRM2, eIF4A] (Mus musculus) PubMed

 11786.

Activity of endonuclease WEN1 and WEN2 is modulated by histones. [ WEN1, WEN2] (Mus musculus) PubMed

 11787.

Data suggest that the ligand binding preferences of LTP from maize and barley result from a range of small sequence changes spread throughout the protein structures; palmitate and caprate were used as ligands. [ltp/ltp1; lipid transfer protein] (Mus musculus) PubMed

 11788.

review of recent studies that have begun to shed light on the role of CagA polymorphism in H. pylori disease [CagA] (Mus musculus) PubMed

 11789.

study describes an S314N mutation in the NP gene of H5N1 virus and shows that it caused a defect in nuclear accumulation of NP at non-permissive temperature and contributed to the ts phenotype [NP, H5N1 virus] (Mus musculus) PubMed

 11790.

The data sets used, included the proteins HCV E1, E2 and P7 as the binders (non-self antigens) and the GAD65 and ICA69, which have an association with diabetes, as non-binders (self-antigens).[E1, E2, P7] (Mus musculus) PubMed

 11791.

The PfI2 protein could play a role in the regulation of the P. falciparum cell cycle through its PfPP1 phosphatase regulatory activity.[PfI2] (Mus musculus) PubMed

 11792.

We report the expression of the dense granular protein GRA7 in E. tenella and localization of its protein products to different compartments of different stages of the parasites. [GRA7] (Mus musculus) PubMed

 11793.

This study shows that parasite Macrophage migration inhibitory factor (MIF) is widely expressed and may have potential effects on the immune system of its host, the chicken.[Mif] (Mus musculus) PubMed

 11794.

These results suggest the following: (1) lack of strict association between the presence of esp and biofilm formation and (2) widespread biofilm formation capacity among different sources of E. faecalis isolates derived from bovine mastitis.[esp] (Mus musculus) PubMed

 11795.

The results of mutation analysis of CydX suggest that few individual amino acids in the small protein are essential for function, at least in the context of protein overexpression. (Mus musculus) PubMed

 11796.

This study analyzed flagellum assembly in a temperature-sensitive flgE mutant of Salmonella enterica serovar Typhimurium.[flgE] (Mus musculus) PubMed

 11797.

TsoI gene contained 3348 bp and encoded for a large polypeptide of 1116 amino acid. [TsoI] (Mus musculus) PubMed

 11798.

the fusidic acid (FA) resistance rate is low in Staphylococcus aureus, and the fusB gene is responsible for the resistance.[fusB] (Mus musculus) PubMed

 11799.

Wound-related staphylococcal extracellular adherence protein (Eap) may provide a major cellular invasin function, thereby enhancing the pathogen's ability to hide from the host immune system during acute and chronic skin infection.[EAP] (Mus musculus) PubMed

 11800.

(NK-kappaB) Both NF-kappaB/p50 and NF-kappaB/p65 are increased in spinal cord following cervical spondylotic myelopathy. (Mus musculus) PubMed

 11801.

OsPIANK1 acted as a positive regulator in rice basal defense mediated by SA- and JA-signaling pathways [PIANK1] (Mus musculus) PubMed

 11802.

The lrt1 gene participates in the spatial distribution of initiation, but not in its frequency. Later, the development of lateral roots is strongly affected. [lrt1] (Mus musculus) PubMed

 11803.

A deletion of isoleucine in position 177 of LiaF, a member of the three-component regulatory system LiaFSR involved in the cell envelope response to antimicrobials, is directly responsible for a daptomycin-tolerant phenotype. [LiaF] (Mus musculus) PubMed

 11804.

The mptS (metallophosphatase type from Streptomyces) gene is required for spore dormancy.[mpts] (Mus musculus) PubMed

 11805.

In the presence of glucose, CovR binds bibA promoter in vivo, suggesting that CovR may act as a negative regulator or a repressor. [CovR], [bibA] (Mus musculus) PubMed

 11806.

These results imply that TcpA is involved in normal hyphal branch establishment during vegetative growth and also has a role in the balance between asexual and sexual differentiation.[TcpA] (Mus musculus) PubMed

 11807.

G6PD knockdown reduces egg production and hatching in C. elegans, which are possibly associated with enhanced oxidative stress and altered MAPK pathways. (Glucose 6-phosphate dehydrogenase) (Mus musculus) PubMed

 11808.

The pattern of regulation of SslE secretion suggests that SslE plays a role in colonization of mammalian hosts by non-pathogenic as well as pathogenic E. coli.[SslE] (Mus musculus) PubMed

 11809.

These results suggest a role for ChvI as both a direct activator and repressor of transcription.[ChvI] (Mus musculus) PubMed

 11810.

The ppk/pstS double mutant was able to incorporate more than one fourth of the inorganic phosphate incorporated by the wt strain, whereas phosphate incorporation was almost completely impaired in the pstS mutant.[ppk, pstS] (Mus musculus) PubMed

 11811.

Results indicate that OstA2 mainly contributes to the trehalose pool of strain 1CP, while OtsA1 seems to be involved in the overproduction of trehalose lipids.[OtsA1, OtsA2] (Mus musculus) PubMed

 11812.

Five minutes light exposure are sufficient to induce conF or conJ expression in vegetative mycelia.[conF, conJ] (Mus musculus) PubMed

 11813.

These findings suggest that increased ROS levels, often associated with cardiovascular conditions in advanced age, play a protective role in endothelial homeostasis by inducing AMPK-eNOS axis [AMPK]. (Mus musculus) PubMed

 11814.

ExbD is essential for maintenance of periplasmic buffering and membrane potential by transferring energy required for nickel uptake.[ExbD] (Mus musculus) PubMed

 11815.

Transcription factor Bcr1 up-regulates 8 Candida albicans genes that are involved in impermeability, impenetrability, and drug resistance of Candida albicans biofilms. [Bcr1] (Mus musculus) PubMed

 11816.

SlyD might contribute to gastric pathogenicity in Helicobacter pylori-associated diseases.[SlyD] (Mus musculus) PubMed

 11817.

The presence of cagA gene in larynx cancer tissues significantly decreases survival rate and increases the disease recurrence possibilities.[cagA] (Mus musculus) PubMed

 11818.

These findings suggest that HBeAg suppresses the specific cellular immunity to clear the virus, and eventually lead to immune tolerance to HBV infection (Mus musculus) PubMed

 11819.

A mutation was identified that caused pleiotropic defects in polar organelle synthesis, and revealed the surprising result that some CtrA-dependent promoters are more sensitive to changes in CtrA concentration than others. (Mus musculus) PubMed

 11820.

These results indicate that Candida albicans Rax2 is important for establishing sites of emergence of yeast and hyphal daughters and for maintaining the linearity of hyphal growth.[Rax2] (Mus musculus) PubMed

 11821.

This study reports the characterization of Lpn, a novel trypanosome protein, and provides insight into its enzymatic activity and function in phospholipid biosynthesis.[Lpn] (Mus musculus) PubMed

 11822.

Analysis of the antibiotic resistance traits identified a metallo-ss-lactamase, a novel NDM variant, NDM-7.[NDM-7] (Mus musculus) PubMed

 11823.

Lr67 and Lr34 confer broad spectrum resistance to multiple pathogens. [Lr67, Lr34] (Mus musculus) PubMed

 11824.

PfEMP1 domain DBL2betaPF11_0521 binds ICAM-1 in the low nM range and relate the structure of this domain with its function and immunogenicity.[PfEMP1] (Mus musculus) PubMed

 11825.

these data support a role for ACAP-A in the control of the actin cytoskeleton organization and dynamics through an ArfA-dependent mechanism. [ACAP-A] (Mus musculus) PubMed

 11826.

pneumolysin binding to lipid raft microdomains in human corneal epithelial cells [Ply] (Mus musculus) PubMed

 11827.

These data confirm the biological relevance of the VipA-VipB interaction, which is essential for the type VI secretion system activity of many important human pathogens.[VipA, VipB] (Mus musculus) PubMed

 11828.

Bhr2 localizes to telomeres, and in concert with Rad51 promotes telomere maintenance (Brh2). (Mus musculus) PubMed

 11829.

rotation rate and activity of a V-ATPase [V-ATPase] (Mus musculus) PubMed

 11830.

We have conclusively shown that the C.trachomatis plasmid CDS6 is responsible for the plasmid-associated phenotype of glycogen accumulation/biosynthesis. [CDS6] (Mus musculus) PubMed

 11831.

SNPs within the isopentenyl transferase 2 is associated with kernel weight in maize inbreds. [IPT2] (Mus musculus) PubMed

 11832.

The Deltadap1 mutant displayed growth defects under iron-limited conditions, decreased azole tolerance, decreased production of ergosterol, and increased accumulation of 14alpha-methylated sterols lanosterol and squalene.[dap1] (Mus musculus) PubMed

 11833.

DcsD and DcsG are necessary for the syntheses of O-ureido-L-serine and D-cycloserine, respectively. DcsD was also able to catalyze the synthesis of L-cysteine when sulfide was added instead of hydroxyurea. [DcsD, DcsG] (Mus musculus) PubMed

 11834.

NAC41 and NAC100, are transcriptionally induced in response to Colletotrichum graminicola infection. [NAC41, NAC100] (Mus musculus) PubMed

 11835.

For the first time, authors demonstrate that Pfs is essential for the virulence of Staphylococcus aureus.[Pfs] (Mus musculus) PubMed

 11836.

Physcomitrella patens FHY1 (PpFHY1) is functionally equivalent to Arabidopsis FHY1 and plays a key role in phytochrome nuclear transport and high-irradiance responses (HIRs) signaling in P. patens. (Mus musculus) PubMed

 11837.

EndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and alpha1-acid glycoprotein. [EndoS2] (Mus musculus) PubMed

 11838.

The protein phosphatase PP2A(Cdc55) dephosphorylates APC/C, thereby counteracting the activity of the mitotic kinase Cdc28.[Cdc55] (Mus musculus) PubMed

 11839.

Higher expression of phosphodiesterase-5 (PDE5) in muscle cells from fundus correlates with tonic phenotype of muscle. (Mus musculus) PubMed

 11840.

These findings show that drebrin contains a cryptic F-actin-bundling activity regulated by phosphorylation and provide a mechanistic model for microtubule-F-actin coupling.[F-actin] (Mus musculus) PubMed

 11841.

Site-directed mutagenesis showed that the complementary strand-binding site and the wedge of ExoX (exonuclease x) are dsDNA specific. [ExoX] (Mus musculus) PubMed

 11842.

The significant differences were found in liver transcript levels from fed and fasted fish for the reference genes, arp and ef1a, when these were normalized to total RNA.(arp) (Mus musculus) PubMed

 11843.

Ciona intestinalis peroxinectin is a novel component of the peroxidase-cyclooxygenase gene superfamily upregulated by LPS. [CiPxt] (Mus musculus) PubMed

 11844.

XCL1 is a pathogen recognition molecule involved in antimicrobial innate immunity in Xenopus. [XCL1] (Mus musculus) PubMed

 11845.

These results provide in vivo evidence of Wnt pathway activation by CagA downstream of or in parallel to the beta-catenin destruction complex and upstream of Tcf4.[CagA] (Mus musculus) PubMed

 11846.

Study presented evidence that a sophisticated regulatory network involving the DnaK/Hsp70 chaperone and the protease Lon controls DnaA stability in C. crescentus. [Lon protease] (Mus musculus) PubMed

 11847.

The cysteine of the unique HDCF loop is indispensable for catalytic activity of the sterol carrier protein-2. [Scp2 protein, Trypanosoma brucei] (Mus musculus) PubMed

 11848.

The cysteine of the unique HDCF loop is indispensable for catalytic activity of the sterol carrier protein-2. [Scp2 protein, Leishmania mexicana] (Mus musculus) PubMed

 11849.

FCP1/2 and WOX4 are likely to be involved in maintenance of the vegetative meristem in rice. [WOX4, FCP1, FCP2] (Mus musculus) PubMed

 11850.

The dsCYC2 is a transcriptional target of the blue light sensor AUREOCHROME1a, which functions synergistically with the basic leucine zipper (bZIP) transcription factor bZIP10 to induce dsCYC2 transcription. [AUREO1a] (Mus musculus) PubMed

 11851.

Mutations in active site of protoporphyrinogen oxidase (HemG) suggest that IS-INP0341 inhibits this domain of HemG and that HemG and heme metabolism are important for C. trachomatis infectivity. [HemG] (Mus musculus) PubMed

 11852.

Ymr134wp is essential for aerobic growth due to its function in ergosterol biosynthesis, in maintaining mitochondrial and plasma membrane integrity and impacting the iron homeostasis, respiratory metabolism and antioxidant response.[YMR134W] (Mus musculus) PubMed

 11853.

Authors demonstrated that the transmembrane domain, which comprises two-thirds of this 35 amino acid protein, is necessary and sufficient for interaction with the entry-fusion complex and function in cell entry.[O3 protein] (Mus musculus) PubMed

 11854.

NlpA plays an important role in the production of vesicles in stationary phase. (Mus musculus) PubMed

 11855.

The present report gives a comprehensive characterization of the composition as well as the position of the spacer and MrpA binding sites within mrpS, the 36-bp recombination site.[MrpA] (Mus musculus) PubMed

 11856.

The results suggest that MgaSpn might recognize particular DNA conformations to achieve DNA-binding specificity (MgaSpn). (Mus musculus) PubMed

 11857.

Overall, these data indicate that the HEX1 gene plays a direct role in the asexual reproduction and virulence of Fusarium graminearum and facilitates viral RNA accumulation in the Fusarium graminearum virus 1-infected host fungus. (Mus musculus) PubMed

 11858.

Dihydrodipicolinate synthase from Campylobacter jejuni: kinetic mechanism of cooperative allosteric inhibition and inhibitor-induced substrate cooperativity(Dihydrodipicolinate synthase ) (Mus musculus) PubMed

 11859.

The light-induced degradation of ROC15 protein is one of the triggers for resetting the circadian clock in C. reinhardtii. [Roc15 - RHYTHM OF CHLOROPLAST 15] (Mus musculus) PubMed

 11860.

Studies identified and characterized two TLR7 (with one probably a pseudogene) and three TLR8 genes (TLR8a2, TLR8b1 and TLR8b2)[TLR7, TLR8a2, TLR8b1 and TLR8b2]. (Mus musculus) PubMed

 11861.

The present data demonstrate the importance of motilin in anxiety.[Motilin] (Mus musculus) PubMed

 11862.

HAL2 overexpression recovered the salt stress sensitivity of bdf1 mutation.[Hal2, Bdf1] (Mus musculus) PubMed

 11863.

we identified insertion/deletions (indels) in the conserved domain of BEM46 protein, which allow to differentiate fungal classes such as ascomycetes from basidiomycetes[bud emergence 46 protein] (Mus musculus) PubMed

 11864.

In summary, the vaccinia virus N2 protein is an intracellular virulence factor that inhibits IRF3 activity in the nucleus. (Mus musculus) PubMed

 11865.

These data suggest that porcine reproductive and respiratory syndrome virus nsp1beta may selectively suppress cellular gene expression, including expression of genes involved in the host innate immune function.[nsp1beta] (Mus musculus) PubMed

 11866.

UNC-116/KHC acts in part with the cell and axon migration molecules UNC-6/Netrin and UNC-40/DCC in this process, but in parallel to SAX-3/Robo.[UNC-116, UNC-40] (Mus musculus) PubMed

 11867.

Pde1 and Pde2 regulated dimorphic growth and pathogenicity.[Pde1, Pde2] (Mus musculus) PubMed

 11868.

the crystal structure of Saccharomyces cerevisiae RIB7 at 2.10 A resolution and its complex with NADPH at 2.35 A resolution, is reported.[RIB7] (Mus musculus) PubMed

 11869.

the microRNA miR-204 promotes both mesenchymal neural crest and lens cell migration and elongation by the direct targeting of the Ankrd13A gene.[Ankrd13a, mir 204] (Mus musculus) PubMed

 11870.

The present study demonstrated alterations in the gene expression profile of GC-1 spg germ cells transfected with SPATA12. [SPATA12] (Mus musculus) PubMed

 11871.

Single point mutation induced alterations in the equilibrium structural transitions on the folding landscape of HIV-1 protease(protease) (Mus musculus) PubMed

 11872.

OsHsp70CP1 is essential for chloroplast differentiation from the proplastids under high temperatures. Transcripts were greatly increased by heat stress. [OsHsp70CP1] (Mus musculus) PubMed

 11873.

MtCaMP1 encodes a stress-responsive EF-hand protein that plays a regulatory role in response of plants to drought and salt stress [MtCaMP1] (Mus musculus) PubMed

 11874.

Expression of chkINA is neuron-specific and widespread in the chicken brain (Mus musculus) PubMed

 11875.

CPT1B expression isnfluenced by a cis-acting expression quantitative trait locus in muscle.[CPT1B] (Mus musculus) PubMed

 11876.

The chromosomally encoded transcriptional regulator, Rgg, directly represses both bacteriophage promoters controlling the expression of Spd-3.[Rgg] (Mus musculus) PubMed

 11877.

Bridge-induced chromosome translocation is elicited by the Rad54 helicase/Rdh54 and completed by a Pol32-independent replication pathway.[Rad54, Rdh54, Pol32] (Mus musculus) PubMed

 11878.

Data show that a miRNA, hsv1-mir-H27, encoded within the genome of herpes simplex virus 1 (HSV-1), targets the mRNA of the cellular transcriptional repressor Kelch-like 24 (KLHL24): [mir-H27] (Mus musculus) PubMed

 11879.

LLRKxGxKG region of nsp1 may play an important role in pathogenetic mechanisms of mouse hepatitis virus (Mus musculus) PubMed

 11880.

The identification of 9 operons, 6 of which are activated by ModE, one of them MorA, with an unusual initiation codon.[ModE; MorA] (Mus musculus) PubMed

 11881.

atherosclerosis induced by diet (cholesterol and coconut oil) produced a reduction in aortic PGC-1alpha expression; observed results suggest PGC-1alpha could be considered to be a link between the main atherosclerotic processes and alterations of other factors involved in vascular wall integrity [PGC-1alpha] (Mus musculus) PubMed

 11882.

Data suggest that mutation in tps1 yields a strain that irreversibly converts its entire adenosine nucleotide pool into inosine upon exposure to glucose; plasma membrane proton-translocating ATPase activation was down-regulated. [tsp1] (Mus musculus) PubMed

 11883.

Authors propose a model placing Rrp1 and Rrp2 functioning together with Swi5 and Srs2 in a synthesis-dependent strand annealing homologous recombination repair pathway (Rrp1 and Rrp2). (Mus musculus) PubMed

 11884.

The results of the present study indicate that 11beta-HSDs are important in the development of steroid-induced avascular necrosis of the femoral head.[11-betaHSD1, 11-betaHSD2] (Mus musculus) PubMed

 11885.

Authors identified an Anopheles salivary gland protein, named CSP-binding protein (CSPBP), that interacts with Plasmodium berghei CSP.[CSP-binding protein] (Mus musculus) PubMed

 11886.

The study performed X-ray crystal structure analyses of the Glu506Ala and Glu506Ile mutants of CueO, showing the formation of a compensatory proton transport pathway with only water molecules.[CueO] (Mus musculus) PubMed

 11887.

Enterococcus faecium isolates from cattle were positive for tcrB with a prevalence of 3.8% (22/576); prevalence was higher among cattle fed diets supplemented with copper. The tcrB-positive isolates always contained both erm(B) and tet(M) genes.[tcrB] (Mus musculus) PubMed

 11888.

key pathways and directly modulated targets of OsMADS1 were deduced from expression analysis after its knockdown and induction in developing florets.[OsMADS1] (Mus musculus) PubMed

 11889.

Our approach led us to identify the LYT1 interaction profile, thereby providing insights into the molecular mechanisms that contribute to parasite stage development and pathogenesis of T. cruzi infection. (Mus musculus) PubMed

 11890.

Gel shift experiments showed that COS1 binds to DNA elements with A4GA3 motif.[COS1] (Mus musculus) PubMed

 11891.

the active-state structure of a Na(+)/H(+) antiporter, NapA from Thermus thermophilus, at 3 A resolution, solved from crystals grown at pH 7.8 [NapA] (Mus musculus) PubMed

 11892.

Functional characterization of Staphylococcus epidermidis IcaB, a de-N-acetylase important for biofilm formation (IcaB) (Mus musculus) PubMed

 11893.

Data from Hsp104(-) strain suggest no mismatch between transcription level and functional oxidoreductases is seen, corresponding to lower oxidative stress and higher cell viability; Hsp104 is involved in oxidative stress in prion-rich cells. [Hsp104] (Mus musculus) PubMed

 11894.

These findings point to effects of trans-sialidase that could influence the escape of immature thymocytes in Chagas disease.[trans-sialidase] (Mus musculus) PubMed

 11895.

[Bdf2] identified Bdf2, which is homologous to the mammalian bromodomain and extraterminal (BET) family double bromodomain proteins involved in diverse types of cancers, as a factor required for proper boundary function at IRCs. (Mus musculus) PubMed

 11896.

Authors found that rotavirus Non-Structural Protein-1 (NSP1) interacts with TRAF2 and degrades it in a proteasome dependent manner. (Mus musculus) PubMed

 11897.

data together with those on the biological activity of the V3 individual residues clearly show that these conserved structural motifs of gp120 represent potential HIV-1 weak points most suitable for therapeutic intervention (gp120) (Mus musculus) PubMed

 11898.

These results suggest that the PA and HA gene-mediated high virus replication and the intense innate immune response in the brain contribute to the high virulence of H5N1 virus in ducks.[PA, HA] (Mus musculus) PubMed

 11899.

RflM encodes a transcriptional repressor, RflM, which fine-tunes the flagellar master operon flhDC expression levels.[Rflm] (Mus musculus) PubMed

 11900.

Authors found that the Golgi protein acyl-coenzyme A binding domain-containing 3 (ACBD3), interacts with the 3A proteins of poliovaccine Sabintpe 2 and coxsackievirus A17 at viral RNA replication sites. (Mus musculus) PubMed

 11901.

The degree of ureaplasma MBA variation in vivo increased with the duration of gestation.[MBA] (Mus musculus) PubMed

 11902.

The HI loop plays a role in adeno-associated virus serotype 5 capsid assembly and genome packaging, and VR-IV and VR-VII are associated with transduction and antigenic differences, respectively, between the AAVs.[capsid protein] (Mus musculus) PubMed

 11903.

These results suggest that OsAT10 is a p-coumaroyl coenzyme A transferase involved in glucuronoarabinoxylan modification.[At10] (Mus musculus) PubMed

 11904.

Although serum opacity factor (SOF) sequences in different Group C isolates are identical, different opacification activities are observed with three types of variations in the upstream sequence characterized by an IS98-like elements. [SOF] (Mus musculus) PubMed

 11905.

These results suggest a new role for Staufen-1 as a cellular Rec and human endogenous retrovirus family HERV-K Gag cofactor.[rec, gag] (Mus musculus) PubMed

 11906.

The YaaH protein plays a functional role in acetate and succinate uptake in Escherichia coli. (Mus musculus) PubMed

 11907.

SecE functions to guide and stabilize the open pore state of SecY [SecE] (Mus musculus) PubMed

 11908.

These data suggest that the M2 amphipathic helix is required for proper localization in the host membrane and that this has implications for virus budding and scission.[M2] (Mus musculus) PubMed

 11909.

These observations suggest that PB2 627K is supported in Eurasian-lineage viruses; in contrast, PB2 627K carries a significant fitness cost in the historical pre-Asian 50-92 virus. (Mus musculus) PubMed

 11910.

These results indicate that the sequence MRKTKLAPT can be functionally considered as a nuclear localization signal.[3D] (Mus musculus) PubMed

 11911.

The study indicates that TbRAP1 helps to determine the chromatin structure at the insect stage, which likely contributes to its strong silencing effect on variant surface glycoproteins (RAP1). (Mus musculus) PubMed

 11912.

Studies determined the crystal structures of the holo-pro- and the apo-pro-forms of melB tyrosinase: [melB] (Mus musculus) PubMed

 11913.

results support the hypothesis that the haemagglutinin D222G change may result from adaptation of viral receptor specificity to the lower respiratory tract; amino acid changes at HA position 222 may be the result of viral intra-host evolution leading to the generation of variants with an altered viral tropism [hameagglutinin] (Mus musculus) PubMed

 11914.

C10orf116 is important in regulating glucose transport in adipocytes as well as the number of preadipocytes.[C10orf116] (Mus musculus) PubMed

 11915.

MtSAP1 is involved in the response processes to various abiotic constraints. MtSAP1 is not involved in signaling pathway responsible for the proline accumulation in stress conditions. [MtSAP1] (Mus musculus) PubMed

 11916.

study characterized TeaC, a putative homologue of S. pombe Tea4; TeaC localized to hyphal tips and to septa; TeaC interacted with the cell end marker protein TeaA at hyphal tips and with the formin SepA at hyphal tips and at septa [TeaC] (Mus musculus) PubMed

 11917.

DHX34 and NBAS act in concert with core nonsense-mediated mRNA decay factors to co-regulate a large number of endogenous RNA targets (DHX34 and NBAS). (Mus musculus) PubMed

 11918.

Data suggest that CYP76M6 and CYP76M8 have distinct roles in orzyalexin biosynthesis; both enzymes hydroxylate 3alpha-hydroxy-ent-sandaracopimaradiene, CYP76M6 at C-9beta to yield oryzalexin E, CYP76M8 at C-7beta to yield oryzalexin D. [CYP76M6] (Mus musculus) PubMed

 11919.

Authors conclude that loss of both Ugh and Ure activity significantly reduced the virulence of this fungal pathogen.[Ugh, Ure] (Mus musculus) PubMed

 11920.

These results demonstrate a role of ALL1 in regulating conformational aspects of PS structure and iron homeostasis.[ALL1] (Mus musculus) PubMed

 11921.

These results indicate that Streptococcus pneumoniae-microglial cell interplay is influenced by the presence of Spr1875, suggesting that this protein may play a role in the pathogenesis of pneumococcal meningitis.[Spr1875] (Mus musculus) PubMed

 11922.

A unique mutation, Vpr R50G, was identified in the macaques that survived regardless of morphine exposure.[Vpr] (Mus musculus) PubMed

 11923.

Authors describe a direct link between a deletion in the foot-and-mouth disease virus 3A protein and disease attenuation in cattle.[3A protein] (Mus musculus) PubMed

 11924.

Authors identified three charged amino acid residues (R245, H246, and D250) in the surface-exposed C-terminus of the coat protein that are critical for virus cell-to-cell and long-distance movement.[coat protein] (Mus musculus) PubMed

 11925.

Fluorescence imaging of GFP-fused periplasmic components of Na+-driven flagellar motor using Tat pathway in Vibrio alginolyticus (Mus musculus) PubMed

 11926.

The C5aR binding Panton-Valentine Leukocidin component, LukS-PV, is a potent inhibitor of C5a-induced immune cell activation.[Luk-S] (Mus musculus) PubMed

 11927.

A genome-wide RNAi screen for persistent expression of GPEET in glycerol-free medium identified a novel protein, NRG1 (Nucleolar Regulator of GPEET 1), as a negative regulator.[GPEET, NRG1] (Mus musculus) PubMed

 11928.

Using competitive and enzymatic assays the study uncovered the chemical nature of the enterolysin A receptor, which is a lipoteichoic acid. [enterolysin A] (Mus musculus) PubMed

 11929.

The authors studied a maize peptide transporter they named ZmPTR1. ZmPTR1 expression was found in the scutellar epithelial cells during seed imbibition, but it is also expressed, at a lower level, in shoots and roots of germinating seedlings. [PTR1] (Mus musculus) PubMed

 11930.

The SLL1 gene, important for the elongation of lateral roots in rice, was identified. It encodes a member of the stearoyl-acyl carrier protein fatty acid desaturase family that is the key regulator of overall fatty acid desaturation in plants. [SLL1] (Mus musculus) PubMed

 11931.

In rice, Os03g01700 and Os02g37190 transcripts were highly accumulated in the examined root tissues but were not detected in young embryos or leaves at the indicated days after germination or in the panicle. [03g01700,02g37190] (Mus musculus) PubMed

 11932.

Oscyp71Z2 plays an important role in bacterial blight resistance in rice by regulating diterpenoid phytoalexin biosynthesis and hydrogen peroxide generation. [cyp71Z2] (Mus musculus) PubMed

 11933.

GnTI, an N-acetylglucosaminyltransferase, is important for cytokinin-mediated development and cellulose synthesis. (Mus musculus) PubMed

 11934.

This study reveals how the phosphoinositide-binding activity of the PROPPIN family protein Atg18 is regulated at the membrane association domain and highlights the importance of such phosphoregulation in coordinated intracellular reorganization. (Mus musculus) PubMed

 11935.

Thioredoxin and its reductase denitrosated the S-nitrosated peptide, ntpA, decreased cellular S-nitrosothiol and conferred tolerance against NO, indicating peptide-mediated catalytic NO removal [ntpA] (Mus musculus) PubMed

 11936.

Trypanosoma brucei Mex67 contains a unique and essential N-terminal zinc finger motif.[Mex67] (Mus musculus) PubMed

 11937.

Fur regulates haemolysin production at the transcription level of the vvhBA operon and at the post-translation level by regulating the expressions of two VvhA-degrading exoproteases, VvpE and VvpM.[VvhA, VvpE, VvpM] (Mus musculus) PubMed

 11938.

Tryptogalinin is a tick Kunitz serine protease inhibitor with a unique intrinsic disorder. [Tryptogalinin] (Mus musculus) PubMed

 11939.

Authors observed a decrease in the release of occlusion bodies (OBs) in the hemolymph of the larvae infected with the cg30 mutant virus.[cg30] (Mus musculus) PubMed

 11940.

pH and phosphorylation status regulate the phyA'/phyA'' isoform equilibrium and content in the etiolated maize cells. [phyA] (Mus musculus) PubMed

 11941.

CYP51A encodes an additional sterol 14alpha-demethylase, induced on ergosterol depletion and responsible for the intrinsic variation in azole sensitivity.[CYP51a]CYP51C is required for full virulence on host wheat ears.[CYP51C] (Mus musculus) PubMed

 11942.

Virulence of the tkt1 mutant was slightly lower based on LD50 when compared to the wild type during infection of chickens.[tkt1] (Mus musculus) PubMed

 11943.

These results suggest that MON1 has an essential function in vacuolar assembly, autophagy, fungal development and pathogenicity in Magnaporthe oryzae.[MON1] (Mus musculus) PubMed

 11944.

These findings indicate that Helicobacter pylori VacA inhibits the development of a strong Th1-polarizing response in bone marrow-derived macrophages stimulated with Lactobacillus acidophilus by blocking the production of IFN-beta.[VacA] (Mus musculus) PubMed

 11945.

Dsc2 functions in SREBP recognition and binding.[DSc2, Sre1] (Mus musculus) PubMed

 11946.

PEDF-R is required for the survival and antiapoptotic effects of PEDF on retina cells.[PEDF-R] (Mus musculus) PubMed

 11947.

The movement of individual Cel7A cellobiohydrolases from Trichoderma reesei (TrCel7A) was studied on the surface of insoluble cellulose fibrils to elucidate molecular level details of cellulase activity.[Cel7A] (Mus musculus) PubMed

 11948.

accumulation of phospho-PhoP is linked to activation of PhoQ autophosphorylation by SafA [PHoQ][PhoP][SafA] (Mus musculus) PubMed

 11949.

Acidic phospholipids together with the N-terminal tail of EIIA(Glc) are essential for the high affinity binding of the protein to the maltose transporter MalFGK2.[MalFGK2, EIIA(Glc)] (Mus musculus) PubMed

 11950.

the EnvZ-OmpR two-component system has a role in virulence control of Escherichia coli in Drosophila melanogaster [EnvZ, OmpR from strain BW25113 or BW26424] (Mus musculus) PubMed

 11951.

the clock-controlled CONSTANS (CO)-FLOWERING LOCUS T pathway in Lotus japonicus [FT] (Mus musculus) PubMed

 11952.

AvrLm11 is avirulence gene [AvrLm11] (Mus musculus) PubMed

 11953.

OsDMI3 is an important component in ABA-induced antioxidant defense in rice [DMI3] (Mus musculus) PubMed

 11954.

The positioning of the catalytic His87 into the active site coupled to hydrophobic-gate opening involves the 23S rRNA sarcin-ricin loop and domain III of EF-G and provides a structural basis for the GTPase activation of EF-G. (EF-G) (Mus musculus) PubMed

 11955.

Authors show that the enteropathogenic Escherichia coli-secreted effector protein EspF is critical for complete enteropathogenic Escherichia coli-induced depletion of DNA mismatch repair proteins.[EspF] (Mus musculus) PubMed

 11956.

The study showed that expression of gadA and gadB in luminal E. coli increases with intestinal inflammation and enhances the susceptibility of NC101 to killing by the host.[gadA; gadB] (Mus musculus) PubMed

 11957.

We show that only the first and third WH2 domains of VopF bind G-actin in a non-nucleating, sequestered conformation. Moreover, dimeric WH2 domains in VopF give rise to unprecedented regulation of actin assembly. (VopF) (Mus musculus) PubMed

 11958.

eIF5B interaction with the peptidyl transferase center A loop increases the accuracy of initiation by stabilizing the overall conformation of the 80S initiation complex. (eIF5B) (Mus musculus) PubMed

 11959.

a novel role for Pic2 in copper import into mitochondria, is reported.[Pic2] (Mus musculus) PubMed

 11960.

These findings suggest that heparan sulfate binding site engagement on L1 and L2 capsid proteins induces conformational changes that prepare the virus for downstream events, such as transfer to the uptake receptor, and uncoating.[L2] (Mus musculus) PubMed

 11961.

Thus, cleavage of the VP1/2A junction is not essential for virus viability.[VP1, 2A] (Mus musculus) PubMed

 11962.

a thorough kinetic analysis of Trypanosoma brucei TryS, is presented.[TryS] (Mus musculus) PubMed

 11963.

The C-terminal peptides competitively inhibit the normal catalytic activity of light chain of serotype A Botulinum neurotoxins.[BONT LcA] (Mus musculus) PubMed

 11964.

These results provide the structural basis for the activity of a methicillin antirepressor, MecR2, which would sequester MecI away from its cognate promoter region and facilitate its degradation.[MecR2] (Mus musculus) PubMed

 11965.

N and C domains of allophanate hydrolase catalyze a two-step reaction and contribute to maintaining a dimeric form of the enzyme required for their optimal activities.[allophanate hydrolase] (Mus musculus) PubMed

 11966.

DICER-LIKE 4 protein of Physcomitrella patens (PpDCL4) is essential for the biogenesis of 21 nucleotide (nt) ta-siRNAs [DCL4][DCL3] (Mus musculus) PubMed

 11967.

In Qbeta replicase-mediated RNA synthesis, S1 functions at the termination step by promoting release of the product strand in a single-stranded form.[Ribosomal protein S1] (Mus musculus) PubMed

 11968.

Brain invasion by the ure1, ure7, and nic1 mutant strains that lack urease activity was significantly less effective in a mouse model.[ERE1] (Mus musculus) PubMed

 11969.

This study demonstrated that the capsule defect in the D39 DeltaarcD mutant may not be associated with a deficiency in arginine but rather is likely caused by a loss of interaction between the capsule and the transmembrane protein ArcD. (Mus musculus) PubMed

 11970.

Dephosphorylation of Aly1 by calcineurin serves as a regulatory switch to promote Aly1-mediated trafficking to the vacuole.[Calcineurin] (Mus musculus) PubMed

 11971.

These data suggest that a hepatitis C virus-specific YB-1 protein complex modulates an NS3-dependent step in virus production.[NS3] (Mus musculus) PubMed

 11972.

These data suggest that internal cleavage within the NS3 moiety is a common process that further extends the functional repertoires of the multifunctional NS2-3 or NS3.[NS3] (Mus musculus) PubMed

 11973.

Caulobacter crescentus FtsZ is not an outlier, but shows rapid assembly kinetics similar to FtsZ from related bacteria.[FtsZ] (Mus musculus) PubMed

 11974.

The expression of a Lotus japonicus ascorbate oxidase gene (LjAO1) is induced in the symbiotic interaction with both nitrogen-fixing bacteria and arbuscular mycorrhizal (AM) fungi. [LjAO1] (Mus musculus) PubMed

 11975.

These results identify NF-Y as an important regulator of tbx-2 function in vivo.[NFYA-1] (Mus musculus) PubMed

 11976.

RNase III plays a role in the rapid induction of ribosomal operons during outgrowth and is essential in the absence of the transcriptional regulator Fis, suggesting a linkage of transcription and RNA processing for ribosomal operons in E. coli.(RNase III) (Mus musculus) PubMed

 11977.

The results of this study suggested that the broadly expressed OlfCc1 is required for amino acid detection by the olfactory system. (Mus musculus) PubMed

 11978.

A new Apis mellifera high molecular weight component and allergen of vitellogenin has been identified. [Api m 12 allergen] (Mus musculus) PubMed

 11979.

A gerbil-adapted H. pylori strain with a stable genome has helped to establish that TlpD has important functions for persistent colonization in the stomach.[TlpD] (Mus musculus) PubMed

 11980.

Authors identified a lysophospholipase, VolA (Vibrio outer membrane lysophospholipase A), required for remodeling the Vibrio cholerae membrane architecture using lysophosphatidylcholine-derived fatty acid moieties.[VolA] (Mus musculus) PubMed

 11981.

The oral non-skeletal mesodermal expression and downstream function of two homologs of key vertebrate hematopoietic transcription factors: SpGatac and SpScl, is reported.[S[Scl] (Mus musculus) PubMed

 11982.

Binding of NS1 is equally dependent on the N-terminal domain and conserved beta-loop of the helicase domain.[NS1] (Mus musculus) PubMed

 11983.

These studies demonstrated that mutations in 4 regions investigated was indeed part of the FimH allosteric mechanism.[FimH] (Mus musculus) PubMed

 11984.

Authors propose that the post-translational regulation of CatB, which cleaves the N-terminal 75 aa residues through SmpA is crucial for proper differentiation and osmoprotection of Streptomyces coelicolor.[SmpA] (Mus musculus) PubMed

 11985.

AT-rich discriminator region is crucial for positive control by guanosine tetraphosphate/DksA.[DksA] (Mus musculus) PubMed

 11986.

These findings support the prediction that antibodies to the polymorphic region of MSPDBL2 contribute to protective immunity.[MSPDBL2] (Mus musculus) PubMed

 11987.

Association/dissociation of the nucleotide-binding domains of the bacterial lipid flippase MsbA was studied by luminescence resonance energy transfer.[MsbA] (Mus musculus) PubMed

 11988.

NatC acetylation does not have a vast effect on organelle morphology in yeast [NatC] (Mus musculus) PubMed

 11989.

Data suggest expression of hyaluronan synthase 1 (HAS1) and hyaluronan receptor in endometrium is regulated by estradiol/progesterone; over estrus cycle, hyaluronan system in endometrium is regulated by ovarian steroids. [HAS1, hyaluronan synthase 1] (Mus musculus) PubMed

 11990.

Modification of tryptophan residue of Purine nucleoside phosphorylase (PNP) by N-bromosuccinamide resulted in complete loss of activity showing its importance in catalysis. [PNP] (Mus musculus) PubMed

 11991.

Exoglucanase isolated from Aspergillus fumigatus has high affinity for its substrate, Avicel.[Exoglucanase] (Mus musculus) PubMed

 11992.

the two component regulatory system, CovR/S, is required for optimum infection and transmission from the nasopharynx [CovR][CovS] (Mus musculus) PubMed

 11993.

erythrocyte binding activity of PvTRAg33 [PvTRAg33] (Mus musculus) PubMed

 11994.

a role for NFP in the perception of pathogenic signals [NFP] (Mus musculus) PubMed

 11995.

The other interaction within the complex involved a stutter in the TACC3 coiled-coil and a proposed novel sixth TOG domain in ch-TOG, which was required for microtubule localization of ch-TOG but not TACC3-clathrin. (Mus musculus) PubMed

 11996.

Genes involved in the immune response, the interferon response, and inflammation were upregulated during TGEV infection in the absence of gene 7. (protein 7) (Mus musculus) PubMed

 11997.

By deleting genes encoding glycoproteins gB and gH from the genome of nuclear envelope breakdown (NEBD)-inducing viruses, we demonstrate that these glycoproteins are not required for NEBD but are still necessary for syncytium formation. (gB and gH) (Mus musculus) PubMed

 11998.

PfSec13 is essential for parasite proliferation in human erythrocytes. [PfSec13] (Mus musculus) PubMed

 11999.

Purified and characterized is one of the two ClpB isoforms from Plasmodium falciparum, ClpB1.ClpB1 catalyzes the hydrolysis of ATP and reactivates aggregated luciferase.[ClpB1] (Mus musculus) PubMed

 12000.

alpha-glucuronidases (AguA)is 2523 bp long and codes for a protein of 840 amino acid residues including a putative signal peptide of 19 residues. [AguA] (Mus musculus) PubMed

 12001.

Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast. [Loz1 - Loss Of Zinc sensing 1] (Mus musculus) PubMed

 12002.

Neurotensin cDNA encoded a protein of 495 amino acids that contains the sequences of chicken neurotensin and LANT6 in the C-terminal region. The neurotensin precursor mRNA is preferentially expressed in intestinal tissues.[LANT6] (Mus musculus) PubMed

 12003.

Nonstructural C protein modulates measles virus RNA polymerase activity by binding to the host protein SHCBP1. (C protein) (Mus musculus) PubMed

 12004.

Pseudorabies virus glycoproteins gE/gI are required for efficient anterograde transport of viral particles in axons by mediating the interaction between Us9 and KIF1A. (gE and gE) (Mus musculus) PubMed

 12005.

Human Pol iota and yeast Pol zeta complex could function efficiently in the insertion and extension steps, respectively, of ranslesion synthesis and human Pol kappa and Pol eta could also extend past these lesions, albeit much less efficiently.[REV3] (Mus musculus) PubMed

 12006.

The identification and characterization of a second family of Cdc13-like proteins in the Candida clade, named Cdc13B, is reported.[Cdc13B] (Mus musculus) PubMed

 12007.

This study showed that FeoA and FeoC, as well as the more highly conserved FeoB, are all required for iron acquisition by V. cholerae Feo.[FeoA; FeoB; FeoC] (Mus musculus) PubMed

 12008.

Map-based cloning revealed that NAL2 and NAL3 are paralogs that encode an identical OsWOX3A.[NAL2, NAL3, WOX3A] (Mus musculus) PubMed

 12009.

The combined results better define how sialic acids, acting through NanR, affect the metabolic flux of an important group of host-derived metabolites [NanR] (Mus musculus) PubMed

 12010.

The results suggest that the base-pairing function is the more robust or primary activity of SgrS, as it is just as efficient with or without translation, whereas production of SgrT is limited by the competing riboregulation activity (SgrS). (Mus musculus) PubMed

 12011.

OsHOS1 is important in the modulation of the cold stress signaling in rice. [OsHOS1] (Mus musculus) PubMed

 12012.

Vam7p binds to membranes through its combined affinities for several vacuolar membrane constituents.[Vam7] (Mus musculus) PubMed

 12013.

Data suggesting that some immunosuppressive processes exhibited by gp41 are initiated by novel motifs located within the hydrophobic regions of the protein. [envelope glycoprotein 41; OPINION/REVIEW] (Mus musculus) PubMed

 12014.

The Lys-601 residue provides a moderate hydrophobicity level within the gp41 loop core that contributes to the proper structure and function of the loop inside and outside the membrane.[Gp41] (Mus musculus) PubMed

 12015.

Brassinosteroid biosynthesis is regulated in a SUB1A-dependent manner during submergence.[SUB1A] (Mus musculus) PubMed

 12016.

In this study, it was found that purified MacA, a periplasmic membrane fusion protein, contains one tightly bound rough core lipopolysaccharide molecule per MacA molecule. (Mus musculus) PubMed

 12017.

Reb1p-mediated regulation of diacylglycerol kinase plays a major role in its in vivo functions in lipid metabolism.[Reb1p, DGK1] (Mus musculus) PubMed

 12018.

The temperature sensitive mutation of TrmD decreases the catalytic efficiency of the enzyme to 1% at the permissive temperature, and at the nonpermissive temperature, it renders further deterioration of activity to 0.1%.[TrmD] (Mus musculus) PubMed

 12019.

The target of tae-miR408, TaCLP1, play an important role in regulating resistance of host plants to abiotic stresses and stripe rust. [TaCLP1] (Mus musculus) PubMed

 12020.

OsMSH5 functions upstream of OsZIP4, OsMER3, and HEI10 in class I crossover formation.[OsMADs16, OsMADS3, OsMADS58] (Mus musculus) PubMed

 12021.

OsMSH5 functions upstream of OsZIP4, OsMER3, and HEI10 in class I crossover formation.[MSH5] (Mus musculus) PubMed

 12022.

These results present the first mechanistic description of EutR gene regulation and reveal a novel role for EutR in enterohemorrhagic Escherichia coli pathogenesis.[EutR] (Mus musculus) PubMed

 12023.

OsGR3 possibly plays a role in salt stress and biotic stress tolerance. (Mus musculus) PubMed

 12024.

This study examines how SgrS regulation of different targets impacts growth under different nutritional conditions when sugar-phosphate stress is induced.[SgrS] (Mus musculus) PubMed

 12025.

The causative agent of leishmaniasis, Leishmania major, expresses an FMN-containing nitroreductase (LmNTR) that metabolizes a wide range of substrates.[LmNTR] (Mus musculus) PubMed

 12026.

YpkA plays an important role in hyphal morphogenesis that also affects endocytosis and vacuolar distribution in A. nidulans. [ypkA] (Mus musculus) PubMed

 12027.

using a series of long molecular dynamics simulations, this study reveals how the selectivity filter is sterically locked in the inactive conformation of KcsA by buried water molecules bound behind the selectivity filter [KcsA] (Mus musculus) PubMed

 12028.

The full catalytic mechanism of L-asparaginase II involves three sequential steps and requires the nucleophilic attack of a water molecule on the substrate prior to the release of ammonia.[L-asparaginase II] (Mus musculus) PubMed

 12029.

Authors discovered that the predicted enzymatic domain alone is a very poor enzyme and cannot complement the function of AKMT in vivo.[AKMT] (Mus musculus) PubMed

 12030.

OsIRX10 inactivation leads to decreased xylan content in rice culm cell walls and improved biomass saccharification [IRX10] (Mus musculus) PubMed

 12031.

[Sub3] Sub3 plays a central role in colonization of keratinized host structures by M. canis, whatever the host (Mus musculus) PubMed

 12032.

BH4 was indispensable for viability of the embryo in eggs laid by lem (lem/lem(1)) females. [BH4] (Mus musculus) PubMed

 12033.

Repression of Bm-ok encodes a ABC transporter causes a translucent phenotype in the first-instar silkworm larva. [Bm-ok] (Mus musculus) PubMed

 12034.

PulS binds to PulD monomers and targets them to the outer membrane via the lipoprotein sorting pathway components LolA and LolB.[PulD] (Mus musculus) PubMed

 12035.

Data show here that Esp protease (Esp) cleaves autolysin (Atl)-derived murein hydrolases and prevents staphylococcal release of DNA, which serves as extracellular matrix in biofilm: [Esp] (Mus musculus) PubMed

 12036.

The exported protein PbCP1 (P. berghei Cleft-like Protein 1) localises to cleft-like structures in the rodent malaria parasite Plasmodium berghei. [PbCP1] (Mus musculus) PubMed

 12037.

RGB1 is a positive regulator of cellular proliferation, in addition to RGA1. (Mus musculus) PubMed

 12038.

Candidate substrates of budding yeast Saccharomyces cerevisiae Cdk1 were identified and dependency on one or more regulatory cyclins is reported.[CDC2] (Mus musculus) PubMed

 12039.

These data highlight the dynamics of IF2-dependent ribosomal subunit joining and the role played by the N terminus of IF2 in this process.[IF2] (Mus musculus) PubMed

 12040.

interdomain interaction preserves the structural and binding properties of the ModA protein [ModA] (Mus musculus) PubMed

 12041.

The viral particles contain an active K(+) channel in the lipid membrane that surrounds the DNA in the mature virions. [Kcv protein] (Mus musculus) PubMed

 12042.

Zm908p11 - role in pollen tube growth as a profilin ligand (Mus musculus) PubMed

 12043.

Data show that the cellular uracil level was 6.5 times higher in the orotidine 5'-phosphate decarboxylase pyrG89 mutant than in wild type in the presence of exogenous uracil: [PyrG] (Mus musculus) PubMed

 12044.

NleB1 from EPEC binds to host cell death-domain-containing proteins and thereby inhibits death receptor signalling [NleB1] (Mus musculus) PubMed

 12045.

structure and possible drug resistance mechanism of mutant M2 proton channel [M2 proton channel] (Mus musculus) PubMed

 12046.

The expression of TaHPS inhibited amylase activity, which subsequently led to a closure of stomatal apertures and thus improved plant tolerance to salt and drought. [TaHPS] (Mus musculus) PubMed

 12047.

LAT (latency-associated transcripts)expression did not impact on latency establishment in viruses unable to replicate in neurons, and it was not required for the survival of neurons between 3 and 31 days post-infection. [LAT] (Mus musculus) PubMed

 12048.

Suggest that the homodimer of Atg38 functions as a physical linkage between the autophagy-specific phosphatidylinositol 3-kinase subcomplexes to facilitate complex I formation. (Mus musculus) PubMed

 12049.

Study demonstrates that NleF binds to the human Tmp21 protein and subsequently disrupts intracellular protein trafficking.[NleF, enterohemorrhagic E.coli] (Mus musculus) PubMed

 12050.

Slc26aalpha mediates the electrogenic exchange of sulfate or oxalate for chloride or bicarbonate and electroneutral chloride:bicarbonate exchange. Mutant rescue assays show that this transport activity is essential for Slc26aalpha's in vivo function. (Slc26aalpha) (Mus musculus) PubMed

 12051.

structure and function of linoleate diol synthase [LDS] (Mus musculus) PubMed

 12052.

NMR study of complex DsbA/DsbB [DsbA][DsbB] (Mus musculus) PubMed

 12053.

role of histidines in ammonia and methylamine transport [AmtB] (Mus musculus) PubMed

 12054.

Injection of dsRNA suppresses expression of Toll9-1 mRNA in the larval midgut. [Toll9-1] (Mus musculus) PubMed

 12055.

These results suggest that GRA22 is involved in regulating parasite egress in Toxoplasma gondii.[GRA22] (Mus musculus) PubMed

 12056.

Taken together, these results suggest that SarA post-transcriptionally gene expression in a manner that involves binding to and consequently altering the mRNA turnover properties of target transcripts.[SarA] (Mus musculus) PubMed

 12057.

These findings are consistent with a putative role of SmPA28gamma in larval growth/development of the Schistosoma mansoni.[PA28gamma] (Mus musculus) PubMed

 12058.

The arginine GlcNAc transferase activity of NleB was required for bacterial colonization in the mouse model of EPEC infection [nleB] (Mus musculus) PubMed

 12059.

This study reports the structural analysis of both holo- and apo-forms of biotin protein ligase using X-ray crystallography.[biotin protein ligase] (Mus musculus) PubMed

 12060.

These findings indicate that RALP1 is a rhoptry neck erythrocyte-binding protein playing an important role during merozoite invasion of erythrocytes. (Mus musculus) PubMed

 12061.

positively selected residues modulate fitness during urinary tract infections by affecting FimH conformation and function.[FimH] (Mus musculus) PubMed

 12062.

Authors identified a transcriptional regulator, RalR, in the rabbit-specific aEPEC strain, E22 (O103:H2) and examined its involvement in the regulation of virulence.[RalR] (Mus musculus) PubMed

 12063.

VopZ inhibits activation of the kinase TAK1 and thereby prevents the activation of MAPK and NF-kappaB signaling pathways, which lie downstream. (Vopz protein) (Mus musculus) PubMed

 12064.

OsELF3 acts as a floral activator in the long-day photoperiodic pathway via its crosstalk with the circadian clock in rice.[ELF3] (Mus musculus) PubMed

 12065.

a rice gain-of-function mutant leaf inclination1, lc1-D, was identified.[LC1] (Mus musculus) PubMed

 12066.

pku300 and fbn2b represent the few genes capable of regulating endocardial cell proliferation and signaling in zebrafish cardiac valve development.[pku300] (Mus musculus) PubMed

 12067.

CrKin13 depolymerizes cytoplasmic microtubules to provide tubulin precursors for flagellar regeneration. [CrKin13] (Mus musculus) PubMed

 12068.

Authors determined that transforming an HWP2 cassette can complement the lack of filamentation of an Saccharomyces cerevisiae flo11 null strain and impart on its adhesive properties similar to those of a pathogen.[HWP2] (Mus musculus) PubMed

 12069.

These data suggest that prozyme translation may be regulated by decarboxylated AdoMet, a metabolite not previously identified to play a regulatory role.[prozyme] (Mus musculus) PubMed

 12070.

The the diffusible signalling factor contributes to symptom expression but not to invasion of sugar cane stalks by Xanthomonas albilineans strain XaFL07-1, which is mainly controlled by the RpfCG two-component system.[RpfCG] (Mus musculus) PubMed

 12071.

native rSgrA(28-153) protein crystallized in the monoclinic space group P2(1) and diffracted to 3.3 A resolution using an in-house X-ray source, with unit-cell parameters a = 35.84, b = 56.35, c = 60.20 A, beta = 106.5 degrees .[SGRA] (Mus musculus) PubMed

 12072.

The effector protein MoHrip1 from the pathogenic fungus Magnaporthe oryzae was purified and crystallized using the sitting-drop vapour-diffusion method. [MoHrip1] (Mus musculus) PubMed

 12073.

Native crystals of Hrip2 and selenomethionine-labelled crystals were obtained using 2.2 M ammonium sulfate as a precipitant. A native data set was collected to 2.0 A resolution at 100 K[Hrip2 ] (Mus musculus) PubMed

 12074.

The crystal structure of HP1028 demonstrates that it belongs to the lipocalin family. (Mus musculus) PubMed

 12075.

Letm1 has a role in mitochondrial potassium homeostasis [Letm1] (Mus musculus) PubMed

 12076.

The morphology, phenotype, regional distribution, proliferative dynamics, and stage-specific marker expression of Map5 cells in the rabbit and mouse central nervous system, were characterized.[Map5] (Mus musculus) PubMed

 12077.

A conserved role for RsmA in secondary metabolite cluster activation. [RsmA] (Mus musculus) PubMed

 12078.

3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin D2, and other endogenous and xenobiotic carbonyl compounds.[3-hydroxyhexobarbital dehydrogenase] (Mus musculus) PubMed

 12079.

Trp266 determines the binding specificity of a porcine aflatoxin B aldehyde reductase for aflatoxin B1 dialdehyde.[aflatoxin B aldehyde reductase] (Mus musculus) PubMed

 12080.

Deletion of hgrA causes defects in hyphal morphogenesis and the dimorphic transition from yeast cells to hyphae.[HgrA] (Mus musculus) PubMed

 12081.

Data indicte the molecular dynamics (MD) simulations of the Trichoderma reesei Family 6 and Family 7 cellobiohydrolases (TrCel6A and TrCel7A, respectively) bound to cellulose: [TrCel6A and TrCel7A] (Mus musculus) PubMed

 12082.

study of site-specific relaxase activity of a VirD2-like protein encoded within the tfs4 genomic island [VirD2] (Mus musculus) PubMed

 12083.

In this study, a novel gene, GEA1, was found to be required for ascus wall development in Fusarium graminearum.[GEA1] (Mus musculus) PubMed

 12084.

This study shows that expression of ramA is not induced by most substrates of the AcrAB-TolC efflux system, but is increased by mutational inactivation of acrB or when efflux is inhibited.[ramA, AcrAB] (Mus musculus) PubMed

 12085.

Authors demonstrate that the Plasmodium yoelii Pumilio-FBF family member Puf2 allows the sporozoite to remain infectious in the mosquito salivary glands while awaiting transmission.[Pfu2] (Mus musculus) PubMed

 12086.

Wild-type Streptomyces coelicolor PNPase was able to synthesize RNA 3' tails under phosphorolysis conditions while the N459D and C468A mutants could not.[PNPase] (Mus musculus) PubMed

 12087.

These data support the notion that MecA mediates the formation of a ternary SigX-MecA-ClpC complex that sequesters SigX and thereby negatively regulates genetic competence in Streptococcus mutans. (Mus musculus) PubMed

 12088.

These findings establish the idea that calmodulin is required for the transport of mitochondrial tryparedoxin peroxidase to mitochondria through maintenance of translocation competence posttranslation.[calmodulin] (Mus musculus) PubMed

 12089.

Heparin-binding epidermal growth factor-like growth factor (HE-EGF) suppresses claudin-3 expression in uterine luminal epithelium. (Mus musculus) PubMed

 12090.

when bound to the EC, the N interaction surface of NusA shifts from the AR1 domain to its NTD domain [NusA, from strains listed in http://www.jbc.org/content/288/39/28089/T1.expansion.html] (Mus musculus) PubMed

 12091.

These findings imply that SPOR domains localize by binding to septal peptidoglycan and imply that the binding site is associated with the beta-sheet; they also show that FtsN(SPOR) contains a disulfide bond between C252 and C312. (Mus musculus) PubMed

 12092.

This study showed that different mutations of SbmA altered the transport function of the protein.[SbmA] (Mus musculus) PubMed

 12093.

TolCV1 and TolCV2 interact with the MacA protein to form the functional macrolide-specific efflux pump MacAB-TolC. [MacA] (Mus musculus) PubMed

 12094.

These results shed light on the SbmA-mediated internalization of peptide substrates and suggest that the transport of an unknown substrate(s) represents the function of this protein.[SbmA] (Mus musculus) PubMed

 12095.

Spf1, as a P-type ATPase, is essential for endoplasmic reticulum functions and consequent cell wall integrity, implicating a role of endoplasmic reticulum Ca(2+) homeostasis in Candida albicans physiology.[Spf1] (Mus musculus) PubMed

 12096.

This study identified the phenol-soluble modulins as aureolysin-degraded, osteolytic peptides that trigger osteoblast cell death and bone destruction.[aureolysin] (Mus musculus) PubMed

 12097.

YidC protein is a molecular chaperone for LacY protein folding via the SecYEG protein machinery [YidC from strains JS7131, CM124, WAM121, and FTL85] (Mus musculus) PubMed

 12098.

data indicate a distinct action of the Sgp5 locus on the expression of endogenous retroviruses, as compared with two other Sgp loci, Sgp3 and Sgp4 (Sgp4 and Sgp5) (Mus musculus) PubMed

 12099.

site-directed mutagenesis of AcrB in E. coli verified that mutations of residues located along the newly identified path significantly reduced the efflux efficiency, supporting its relevance in in vivo function [AcrB] (Mus musculus) PubMed

 12100.

In the absence of CcaR, the lat and cmcI genes expression was reduced 2,200- and 1,087-fold compared with the wild type.[CcaR] (Mus musculus) PubMed

 12101.

Authors conclude that CovR is an important regulator of Streptococcus agalactiae vaginal colonization and loss of this regulatory function may contribute to the inflammatory havoc seen during the course of infection. (Mus musculus) PubMed

 12102.

N. crassa produce two pheromone receptor gene (pre-1)splice variants that display different transcription profiles. [pre-1] (Mus musculus) PubMed

 12103.

Yr36 is a slow-rusting gene in wheat [Yr36] (Mus musculus) PubMed

 12104.

PenT stimulates penicillin production probably through enhancing the translocation of penicillin precursors across fungal cellular membrane.[PenT] (Mus musculus) PubMed

 12105.

The SNARE protein Sec22p/SEC22 specifically impacts Cesium(+) accumulation in yeast and in plants.[Sec22] (Mus musculus) PubMed

 12106.

maternal Nanog, Pou5f1 and SoxB1 are required to initiate the zygotic developmental program and induce clearance of the maternal program by activating miR-430 expression (Mus musculus) PubMed

 12107.

These mutations did not affect NA enzymatic activity levels or NA cellular localization, but rather affected the stability of NA oligomerization, suggesting that the oligomerization of NA is essential for viral viability.[NA] (Mus musculus) PubMed

 12108.

Two-dimensional diffusion dynamics and stoichiometries of complexes of the bacterial enhancer-binding ATPase PspF during its action at promoters as regulated by inner membrane interacting negative controller PspA, is reported.[PspF] (Mus musculus) PubMed

 12109.

The gene Mayetiola destructor susceptibility-1 on wheat chromosome 3AS encodes a small heat-shock protein and is a major susceptibility gene for infestation of wheat by the gall midge M. destructor.[Mds-1] (Mus musculus) PubMed

 12110.

Shr-mediated iron uptake contributes to Streptococcus pyogenes growth in human blood, and is required for full virulence of serotype M1T1 Streptococcus pyogenes in mouse models of invasive disease.[Shr] (Mus musculus) PubMed

 12111.

Homology models of C elegans Tgt and human Tgt suggest that the replacement of Cys158 and Val233 in bacterial Tgt (Zymomonas mobilis) by valine and accordingly glycine in eucaryotic Tgt largely accounts for the different substrate specificities.[Tgt] (Mus musculus) PubMed

 12112.

Predominant gastric mucosal IL-8 mRNA expression level, and H. pylori infection are relative risks for Thai gastric cancer without correlation with cagA mutation. (Mus musculus) PubMed

 12113.

Substrate binding induced conformational change in the GMPS catalytic cycle. [GMPS] (Mus musculus) PubMed

 12114.

SigB activity importantly influences the production of virulence factors.[SigB] (Mus musculus) PubMed

 12115.

Lack of Ptc6 results in substantial attenuation of the transcriptional response to rapamycin, particularly in the subset of repressed genes encoding ribosomal proteins or involved in rRNA processing.[Ptc6] (Mus musculus) PubMed

 12116.

Data show that nucleotide binding (NB) and a leucine-rich repeat (LRR) (NB-LRR) protein-coding genes: RGA4 (AB604622), RGA5-A (AB604627) and RGA5-B (KC777365) were required for the recognition of the Magnaporthe oryzae: [RGA4, RGA5-A and RGA5-B] (Mus musculus) PubMed

 12117.

MgrA is the major transcriptional regulator of capsule, but not alpha-toxin in vivo. [MgrA] (Mus musculus) PubMed

 12118.

Data indicate direct binding of AVR-Pia (AB498873) and AVR1-CO39 (AF463528) to plant protein RGA5-A : [AVR-Pia and AVR1-CO39] (Mus musculus) PubMed

 12119.

Pht2 is involved in phosphate translocation [Pht2] (Mus musculus) PubMed

 12120.

OsFbx352 plays a regulatory role in the regulation of glucose-induced suppression of seed germination by targeting abscisic acid (ABA) metabolism. [OsFbx352] (Mus musculus) PubMed

 12121.

The results highlight that crystal packing may have a significant impact on the structure of protein-DNA complexes; the simulations provide additional insights regarding why AlkB and ABH2 prefer single-strand and double-strand DNA as substrate.[AlkB] (Mus musculus) PubMed

 12122.

role of the C-terminal domain in L-glutamate secretion [NCgl1221] (Mus musculus) PubMed

 12123.

This work reveals a number of new validated ClpXP substrates, clarifies rules of protease substrate selection, and demonstrates how regulated protein degradation is critical for Caulobacter cell cycle progression.[ClpXP] (Mus musculus) PubMed

 12124.

Lrp1 proved to function upstream of Orb6 in cell morphogenesis [Lrp1] (Mus musculus) PubMed

 12125.

mutated FtmD retained enzymatic activity but did not function under physiological conditions, resulting in blockage of the FTM pathway in A. fumigatus Af293 [ftmD] (Mus musculus) PubMed

 12126.

results reveal that trfA is a previously unrecognized member of the cell wall stress regulon; evidence presented that it is under the transcriptional control of the global thiol/oxidative-stress regulator Spx[trfA, Spx] (Mus musculus) PubMed

 12127.

data provide substantial analysis of walKR promoter function and show that prolonged vancomycin exposure can result in VISA through an IS256-mediated reduction in walKR expression; however, the mechanisms by which this occurs remain to be determined [WalK, WalR] (Mus musculus) PubMed

 12128.

Authors show here that CcrA and CcrB can carry out both excisive and integrative recombination in the absence of any host-specific or SCCmec-encoded cofactors.[CcrA, CcrB] (Mus musculus) PubMed

 12129.

study describes and characterizse satR, an open reading frame as a repressor of satAB; satR is cotranscribed with satAB, and its interruption entails the overexpression of the fluoroquinolone efflux pump [SatR] (Mus musculus) PubMed

 12130.

UvrD assembly state regulates its DNA helicase activity.[UvrD] (Mus musculus) PubMed

 12131.

work describes the first drug:H(+) antiporter from C glabrata reported to be involved in antifungal drug resistance, the QDR2 gene (ORF CAGL0G08624g); expression of CgQDR2 was found to confer resistance to the antifungal drugs miconazole, tioconazole, clotrimazole and ketoconazole [Qdr2] (Mus musculus) PubMed

 12132.

These findings suggest that Hst1 acts as a regulator of stress resistance associated-genes.[Hst1] (Mus musculus) PubMed

 12133.

Data show that the three rice MIKC*-type genes MADS62 (Os08g38590), MADS63 (Os06g11970) and MADS68 (Os11g43740) were expressed exclusively during pollen development, from the unicellular microspore stage to pollen maturation: [MADS62, MADS63, and MADS68] (Mus musculus) PubMed

 12134.

Hxs1 is a high-affinity glucose transporter and required for fungal virulence [Hxs1] (Mus musculus) PubMed

 12135.

These results indicate that FlbB and FlbE are necessary for the proper laeA expression, toxin production, and virulence of Aspergillus fumigatus.[FlbB and FlbE] (Mus musculus) PubMed

 12136.

MIBS complexed with 2-fluoroneryl diphosphate generated during cocrystallization of MIBS with the tertiary allylic diphosphate 2-fluorolinalyl diphosphate.{MIBS] (Mus musculus) PubMed

 12137.

The crystal structure of RamR in complex with multiple drugs, is reported.[RamR] (Mus musculus) PubMed

 12138.

MKRN has a role in embryonic and post-embryonic organogenesis [MKRN]. (Mus musculus) PubMed

 12139.

The 2.3-A structure of a ternary complex of botulinum neurotoxin type B bound to both its protein receptor synaptotagmin II and its ganglioside receptor GD1a, is reported.[botulinum neurotoxin type B] (Mus musculus) PubMed

 12140.

silencing of the TaBTF3 gene may impair tolerance to freezing and drought stresses in wheat and that it may be involved in the response to abiotic stresses in higher plants. [TaBTF3] (Mus musculus) PubMed

 12141.

OsDHAR1 overexpression, capable of functioning in ascorbic acid recycling, and protein folding increases environmental adaptation to paddy field conditions.[OsDHAR1] (Mus musculus) PubMed

 12142.

TaSAP1-A1 was significantly associated with 1,000-grain weight, number of grains per spike, spike length, peduncle length and total number of spikelets per spike in multiple environments. [TaSAP1-A1] (Mus musculus) PubMed

 12143.

The EAR motif is required for OsERF3 to transcriptionally regulate the ethylene synthesis and drought tolerance in rice.[OsERF3] (Mus musculus) PubMed

 12144.

The present study investigated feeding a dietary supplement that has the potential to suppress the inflammatory process in the small intestine of pigs by modulating the activities of NF-kappaB and Nrf2.[NF-kappaB; Nrf2] (Mus musculus) PubMed

 12145.

HtdA, encoded in the R27 plasmid, is involved in the transcriptional repression of four tra operons (F, H, AC and Z).[HtdA] (Mus musculus) PubMed

 12146.

Our results are consistent with the existence of at least two redundant meiotic resolvase activities: one requiring HIM-6 and XPF-1, and the other dependent on SLX-1 and MUS-81. (Mus musculus) PubMed

 12147.

Apsup inhibits apoptosis by preventing proteolytic processing of initiator caspase Dronc. (Mus musculus) PubMed

 12148.

The presence of a leucine at the codon 830, instead of the predominant isoleucine residue, was significantly associated with nonprogression of HIV-1 Infection [gp41] (Mus musculus) PubMed

 12149.

Both SUC1 and Srt1-GFP proteins were found exclusively in phloem companion cells (CCs), only SUC1 complemented the developmental defects of suc2-4 and suc2-5 mutants. (Mus musculus) PubMed

 12150.

we observed a significant decrease in ZnT10 mRNA levels in the APP/PS1-Tg mice. (Mus musculus) PubMed

 12151.

The occurrence of ESBL-producing E. coli in the Swedish broilers is not due to the emergence of a single clone, but rather the spread of a specific incI plasmid carrying blaCTX-M-1.[CTX-M-1] (Mus musculus) PubMed

 12152.

Corynebacterium glutamicum PorH is O-mycoloylated on the Ser 56 side chain. (Mus musculus) PubMed

 12153.

The crystal structure of APR-B, the first for a plant sulfonucleotide reductase, is consistent with a preference for adenosine phosphosulfate. [papr] (Mus musculus) PubMed

 12154.

OsCOM1 plays a rolel in promoting homologous synapsis and recombination in rice meiosis [COM1] (Mus musculus) PubMed

 12155.

PHB1 of Procambarus clarkii interacts with the WSSV envelope proteins VP28, VP26, and VP24. [Vp26] (Mus musculus) PubMed

 12156.

The fusion glycoprotein contains six-helix bundle and with with extensive glycosylation.[F protein] (Mus musculus) PubMed

 12157.

GS1;2 is important in the primary assimilation of ammonium ions taken up by rice roots.[GS1;2] (Mus musculus) PubMed

 12158.

psm-mec RNA suppresses MRSA virulence via inhibition of agrA translation and the absence of psm-mec function in Community acquired-methicillin resistant Staphylococcus aureus causes its high virulence property [agrA] (Mus musculus) PubMed

 12159.

ZmLEA3, was identified and later characterized using transgenic tobacco plants to investigate its functions in abiotic and biotic stresses.[ZmLEA3] (Mus musculus) PubMed

 12160.

CNF1 induced a strong amelioration of both spatial and emotional memory deficits in murine model of Alzheimer's disease [CNF1] (Mus musculus) PubMed

 12161.

MiR-1 encoded by Autographa californica nucleopolyhedrovirus downregulated ODV-E25 mRNA expression.[MiR-1] (Mus musculus) PubMed

 12162.

Conserved inhibitory mechanism and competent ATP binding mode for adenylyltransferases [VbhT] (Mus musculus) PubMed

 12163.

IE1 and WSV056 modulate the G1/S transition by binding to the host retinoblastoma protein. [IE1] (Mus musculus) PubMed

 12164.

Authors identified two homologues of ferredoxin in the genome of the parasitic protist Trypanosoma brucei and named them TbFdxA and TbFdxB.[TbFdxA and TbFdxB] (Mus musculus) PubMed

 12165.

members of miR-99 family (miR-99a, miR-99b, miR-100) were expressed during dermal wound healing.[Microna 99a, Microrna 99b] (Mus musculus) PubMed

 12166.

Decreased expression of miR-430 promotes the development of bladder cancer via the upregulation of CXCR7. (Mus musculus) PubMed

 12167.

[Xyloglucanase] A new xyloglucanase is analyzed and crystallized from Xanthomonas campestris. (Mus musculus) PubMed

 12168.

The over-expression of the alternative sigma factor sigma(54) directly and positively regulates heterologous expression of the oxytetracycline biosynthetic gene cluster in E. coli.[sigma 54] (Mus musculus) PubMed

 12169.

deletion of GPA2, which specifies a G-protein alpha subunit, confers increased resistance to excess copper.[GPA2] (Mus musculus) PubMed

 12170.

FliJ of Salmonella enterica serovar Typhimurium shows a rotor like function in Thermus thermophilus A3B3.[FliJ] (Mus musculus) PubMed

 12171.

We propose that the MUS-81 and XPF-1 endonucleases act redundantly to process late recombination intermediates to form crossovers during Caenorhabditis elegans meiosis (Mus musculus) PubMed

 12172.

The griffithsin dimer manipulate the structure of gp120 (envelope protein gp120) and inhibit the process of viral entry.[gp120] (Mus musculus) PubMed

 12173.

A Pi54-mediated reprogramming of a broad array of genes, which apparently leads to an Magnaporthe oryzae resistant phenotype via detectable changes in the activities of the enzymes involved in the defence pathways. [Pi54] (Mus musculus) PubMed

 12174.

The overexpression of ABCI4 confers resistance to some toxic porphyrins.[ABC14] (Mus musculus) PubMed

 12175.

The NETNES peptide is very flexible in solution, bending itself between asparagine residues and lying down on some carbohydrates and membrane, exposing amino acid residues and some other glycans, mainly terminal mannoses (NETNES). (Mus musculus) PubMed

 12176.

Inactivation of the methyltransferase RlmAII, which methylates the N-1 position of nucleotide G748, located in hairpin 35 of domain II of 23S rRNA, results in increased resistance to telithromycin. [RlmAII methyltransferase] (Mus musculus) PubMed

 12177.

A novel protein encoded by Tb927.2.6100 that was present in a fraction enriched for kinetoplast DNA, was identified.[Tb927.2.6100] (Mus musculus) PubMed

 12178.

ion-motive force is directly coupled to ATP synthesis, via an FF0-ATP synthase with a novel Na+ recognition motif.[F1F0 ATPase] (Mus musculus) PubMed

 12179.

Srr1 contributes to the pathogenesis of endocarditis due to S. agalactiae, at least in part through its role in fibrinogen-mediated platelet binding. [Srr1] (Mus musculus) PubMed

 12180.

Shy1 activity is needed for growth on plates with salicylic acid as a sole carbon source.[Shy1] (Mus musculus) PubMed

 12181.

Authors report that the levels of membrane-associated, full-length Ras1 were higher in hyphae than in yeast, and that yeast contained a shorter, soluble Ras1 species that resulted from cleavage.[Ras1] (Mus musculus) PubMed

 12182.

The characterisation of AmphiAmR4 may provide an insight into the evolutionary relationship between invertebrate Octopamine/Tyramine receptors and vertebrate alpha2-adrenergic receptors (Mus musculus) PubMed

 12183.

The results revealed that it is the P, not the G, gene that is associated with IFN sensitivity. [P protein] (Mus musculus) PubMed

 12184.

vitro and in vivo evidence demonstrates that PfPuf2 binds to the Puf-binding elements in pfs25 and pfs28 to mediate translation repression; this finding provides a renewed view of Pufs as versatile translation regulators and sheds light on their functions in development of lower branches of eukaryotes [Puf2] (Mus musculus) PubMed

 12185.

LytSR two-component regulatory system responds to changes in transmembrane potential and triggers adaptive responses that enable resistance to cationic antimicrobial peptide-induced killing.[LytS; LytR] (Mus musculus) PubMed

 12186.

Insertion sequence (ISEnfa5) plays a role in the mobility of cfr multiresistance gene.[cfr] (Mus musculus) PubMed

 12187.

A high hydrostatic pressure of 25 MPa triggers a degradation of Tat1 which depends on Rsp5 ubiquitin ligase and the EH domain-containing protein End3.[Tat1, Rsp5] (Mus musculus) PubMed

 12188.

These results confirm the involvement of NKIN2 in early endosome transport.[NKIN2] (Mus musculus) PubMed

 12189.

These results and the three-dimensional location of the phosphorylation site suggested that microtubules are depolymerized in response to hyperosmotic stress via alpha-tubulin phosphorylation.[alpha-tubulin] (Mus musculus) PubMed

 12190.

Vps21p is the most important of the three GTPases, followed by Ypt52p, while Ypt53p has an only marginal impact on Candida albicans physiology.[Vps21, Ypt52, Ypt53] (Mus musculus) PubMed

 12191.

Production of Msb2 by C. albicans can partially overcome daptomycin toxicity. [Msb2] (Mus musculus) PubMed

 12192.

Authors report the unexpected finding that in isolation, the 90-residue unstructured N-terminal domain of colicin N is cytotoxic.[cilicin N] (Mus musculus) PubMed

 12193.

The hypothetical protein CT311 possesses a novel nuclear localization signal sequence with dual modules of basic residues for targeting host cell nucleus during Chlamydia trachomatis infection. [CT311] (Mus musculus) PubMed

 12194.

Cross-recognition of heterologous oriTs by MobM could play an important role in the plasmid spreading between bacteria. [MobM] (Mus musculus) PubMed

 12195.

Cleavage of the antitoxin of the parD toxin-antitoxin system is determined by the ClpAP protease and is modulated by the relative ratio of the toxin and the antitoxin. [ParD] (Mus musculus) PubMed

 12196.

Expression, purification and characterization of cecropin antibacterial peptide from Bombyx mori in Saccharomyces cerevisiae.(CecropinXJ) (Mus musculus) PubMed

 12197.

The Alternaria alternata gene AaNPS6, encoding a polypeptide analogous to fungal nonribosomal peptide synthetases, was found to be required for the production of siderophores and virulence on citrus.[NPS6] (Mus musculus) PubMed

 12198.

MoArk1 exhibits conserved functions in endocytosis and actin cytoskeleton organization, which may underlie growth, cell wall integrity and virulence of the fungus.[MoARK1] (Mus musculus) PubMed

 12199.

The epitope-rich regions within nucleoprotein present a promising target for the T-cell-mediated multi-strain influenza vaccine.[Nucleoprotein] (Mus musculus) PubMed

 12200.

DspA/E is toxic to A. thaliana: it promotes modifications, among which the repression of protein synthesis could be determinant in the facilitation of necrosis and bacterial growth.[DspA, DspE] (Mus musculus) PubMed

 12201.

in trypanosomes, a local increase in SCD6 concentration may be sufficient to induce granules by recruiting mRNA. Proteins that bind selectively to the RGG and/or Lsm domain of SCD6 could be responsible for regulating granule type and number. [SCD6] (Mus musculus) PubMed

 12202.

the mutation frequency of apPOL is highly dependent on the intrinsic fidelity of the polymerase and the identity of the template surrounding the potential mismatch. [apPOL] (Mus musculus) PubMed

 12203.

CapE catalyzes the 5-inverting 4,6-dehydration reaction of substrate UDP-d-GlcNAc, followed by a slower 5-back-epimerization (CapE). (Mus musculus) PubMed

 12204.

Through deletion of rscA and rscB genes, the study showed that the Rcs system is involved in the regulation of both polysialic and colanic acids synthesis in E. coli K92.[RcsA, RcsB] (Mus musculus) PubMed

 12205.

The structure reveals that CapE is a member of the SDR (short-chain dehydrogenase/reductase) super-family of proteins. CapE assembles in a hexameric complex stabilized by three major contact surfaces between protein subunits. [CapE] (Mus musculus) PubMed

 12206.

These results suggest that silencing the mitochondrial OsGPX3 gene impairs normal plant development and leads to a stress-induced morphogenic response via hydrogen peroxide accumulation.[GPX3] (Mus musculus) PubMed

 12207.

a direct role for P1 on HCPro suppressor activity or stability, by influencing its conformation during translation, can be excluded.[P1, Hc-Pro] (Mus musculus) PubMed

 12208.

These findings further reinforce the pivotal role of Rpb4/7 in the coordination of distinct steps of gene expression.[Rpb4, Rpb7] (Mus musculus) PubMed

 12209.

The isolation and characterization of TaWRKY79, a wheat class II WRKY transcription factor, is described.[TaWRKY79] (Mus musculus) PubMed

 12210.

The results show that bone morphogenetic proteins (BMPs) could affect the differential direction ofadipose-derived stem cells (Mus musculus) PubMed

 12211.

B. cinerea protein O-mannosyltransferases, especially PMT2, are critical for the stability of the cell wall and are necessary for sporulation and for the generation of the extracellular matrix.[PMT2] (Mus musculus) PubMed

 12212.

In spite of the general belief that ROP2 family proteins are intracellular antigens, NcROP2Fam-1 can also be considered as an extracellular antigen. [NcROP2Fam-1] (Mus musculus) PubMed

 12213.

Knockdown of zPIP4Kalpha by antisense morpholino oligonucleotides led to severe morphological abnormalities, including midbody winding defects at 48hpf. The abnormal phenotype could be rescued, in large part, by injection of human PIP4Kalpha mRNA. [PIP4Kalpha] (Mus musculus) PubMed

 12214.

Rpb9 appears to enhance TFIIS-mediated error excision by facilitating efficient formation of a conformation necessary for RNA cleavag. [Rbp9] (Mus musculus) PubMed

 12215.

Two novel GH11 endo-xylanases from Myceliophthora thermophila C1 (C1), Xyl7 and Xyl8, were purified and shown to act differently toward soluble and insoluble xylans. [XYl7, Xyl8] (Mus musculus) PubMed

 12216.

our study demonstrated a novel functional gene, an insulin-like growth factor (IGF) of SGIV, which may regulate viral replication and cellular processes through multiple mechanisms that appear to be cell type-dependent. [IGF] (Mus musculus) PubMed

 12217.

Null mutation of the BDSF receptor, RpfR, caused a substantial down-regulation of AHL signal production. [RpfR] (Mus musculus) PubMed

 12218.

Authors show that FtsE protein is essential, that depletion of FtsE phenocopies cell defects caused by depletion of FtsX or PcsB, and that changes of conserved amino acids in the FtsE ATPase active site are not tolerated.[FtsE, FtsX] (Mus musculus) PubMed

 12219.

Elimination of IdeS did not significantly influence phagocytic uptake, oxidative-burst induction, cathelicidin sensitivity, resistance to neutrophil or macrophage killing, or pathogenicity in pre- or postimmune mouse infectious challenges.[IdeS] (Mus musculus) PubMed

 12220.

Authors demonstrate that Cps2F is a rhamnosyltransferase that catalyzes addition of the third and fourth sugars in the capsule repeat unit, while Cps2G adds the fifth sugar (glucose).[Cps2F, Cps2G] (Mus musculus) PubMed

 12221.

The objective of this study was to characterize a possible short-term interaction between hypothalamic 5-HT and NPY.[Neuropeptide Y] (Mus musculus) PubMed

 12222.

Silencing of TaLls1 led to leaf cell death.[TaLls1] (Mus musculus) PubMed

 12223.

Using a genetic screen, authors isolated LuxR mutants that separated activation and repression functions at representative promoters.[LuxR] (Mus musculus) PubMed

 12224.

Study shows that T. gondii-induced IL-1beta production is dependent on the classical inflammasome components caspase-1 and ASC.Additionally, a role for a specific parasite factor, dense granule protein GRA15, in T. gondii induction of IL-1beta was demonstrated. (Mus musculus) PubMed

 12225.

VP6 can be recruited by NS80 to its inclusions in both infected and transfected cells.[NS80] (Mus musculus) PubMed

 12226.

Ta-PHR1-A1 is involved in phosphate signalling; and, when over-expressed, it increased phosphate uptake and grain yield of wheat. [Ta-PHR1-A1] (Mus musculus) PubMed

 12227.

OsHCI1 was mainly associated with the Golgi apparatus and drives nuclear export of multiple substrate proteins. [OsHCI1] (Mus musculus) PubMed

 12228.

NSP1 is required for optimum mycorrhization and is involved in the Myc (lipochitooligosaccharides} signaling pathway.[NSP1] (Mus musculus) PubMed

 12229.

DIR protein was upregulated over 180 fold in the Erysiphe necatorinfected leaves, suggesting an important role for stereochemical selectivity in the compatible interaction E. necator-V. vinifera.[DIR] (Mus musculus) PubMed

 12230.

Disruption of kdpA caused a growth defect under low-K(+) conditions, disruption of ktrC resulted in a significant defect in 2 M NaCl, and a DeltaktrC DeltakdpA double mutant exhibited both phenotypes.[kdpA, ktrC] (Mus musculus) PubMed

 12231.

Loop motions important to product expulsion in the Thermobifida fusca glycoside hydrolase family 6 cellobiohydrolase from structural and computational studies (Mus musculus) PubMed

 12232.

The structures of Csa1A and Csa1B were determined by X-ray crystallography, unveiling a peculiar structure with limited structural similarity to other known proteins. (Mus musculus) PubMed

 12233.

Myb3 expression is regulated by miR159a in the wheat response to Puccinia striiformis f. sp. tritici. [Mir159a] (Mus musculus) PubMed

 12234.

MiR-374 was bound to the 3'-UTR of C/EBP-beta and suppressed C/EBP-beta gene. [MiR-374] (Mus musculus) PubMed

 12235.

results suggest a model of strigolactones (SL) signalling that involves SL-dependent degradation of the DWARF 53 repressor mediated by the DWARF 14-DWARF 3 complex [D53] (Mus musculus) PubMed

 12236.

in a DWARF 14- and DWARF 3-dependent manner, strigolactones induce DWARF 53 degradation by the proteasome and abrogate its activity in promoting axillary bud outgrowth [D14, D3, D53] (Mus musculus) PubMed

 12237.

Trf4 is necessary for both mRNA surveillance and maintenance of genome integrity.[Trf4] (Mus musculus) PubMed

 12238.

EhCP112 and EhADH112 co-localize with occludin and claudin-1 at tight junctions.[EhCP112 and EhADH112] (Mus musculus) PubMed

 12239.

The Smb lantibiotic immunity complex that the authors identified is an ABC transporter composed of two proteins: SmbF (the ATPase component) and SmbT (the permease component).[SmbF, SmbT] (Mus musculus) PubMed

 12240.

PI4KIIgamma localized on the plasma membrane and underwent threonine autophosphorylation. [PI4KIIgamma] (Mus musculus) PubMed

 12241.

Sar1 is crucial for proglutelin and alpha-globulin export from the endoplasmic reticulum in rice endosperm.[Sar1] (Mus musculus) PubMed

 12242.

miR7695 targets an alternatively spliced transcript of the Nramp6 gene involved in pathogen resistance.[miR7695][Nramp6] (Mus musculus) PubMed

 12243.

The CdiAEC93 effector protein recognizes the widely conserved BamA protein as a receptor, yet E. coli EC93 does not inhibit other enterobacterial species.[CdiA, BamA] (Mus musculus) PubMed

 12244.

MTP1 transports Zn but also Co, Fe, and Cd with lower affinity. [MTP1] (Mus musculus) PubMed

 12245.

The F103L and M106I mutations in the H5N1 NS1 protein each increased IFN antagonism and mediated interstitial pneumonia in mice that was associated with increased cytoplasmic localization and altered host factor binding.[NS1] (Mus musculus) PubMed

 12246.

These results suggest that OsbZIP71 may play an important role in ABA-mediated drought and salt tolerance in rice.[OsbZIP71] (Mus musculus) PubMed

 12247.

Reduced insulin-like growth factor (IGF) signaling, prevented muscle cell death in dys-1 mutant models of musclular dystrophy, in a daf-16-dependent manner. (Mus musculus) PubMed

 12248.

[AdpA] AdpA regulated the clpP1clpP2 operon expression at specific growth times (Mus musculus) PubMed

 12249.

Amino acid polymorphisms flanking the EPIYA-A motif of Helicobacter pylori CagA C-terminal region is associated with gastric cancer in east China. (Mus musculus) PubMed

 12250.

Wzi is a novel outer-membrane lectin that assists in the formation of the bacterial capsule via direct interaction with capsular polysaccharides. [Wzi] (Mus musculus) PubMed

 12251.

GRMZM2G420119 and GRMZM2G161299 are mitochondrial CoA transporters.[GRMZM2G161299] [GRMZM2G420119] (Mus musculus) PubMed

 12252.

IF2 protein required for innate immunity to stripe rust.[IF2] (Mus musculus) PubMed

 12253.

Triose phosphate isomerase from the blood fluke Schistosoma mansoni: biochemical characterisation(Triose phosphate isomerase) (Mus musculus) PubMed

 12254.

Phosphoribosyl pyrophosphate synthetase (PRS) family acts antagonistically against the septum initiation network.[PRS] (Mus musculus) PubMed

 12255.

results suggest that R780 is critical for AcrB stability [AcrB] (Mus musculus) PubMed

 12256.

crystal structure of the NTD of the CI repressor from phage TP901-1 has been determined at 1.6 A resolution, and at 2.6 A resolution in complex with a 9 bp double-stranded DNA fragment that constitutes a half-site of the OL operator (Mus musculus) PubMed

 12257.

crystal structure of FlhB C-terminal domain and it is importance in the function of FlhB in bacterial secretion system [FlhB] (Mus musculus) PubMed

 12258.

OsCpn60alpha1 is required for the folding of rbcL and that failure of that process is seedling-lethal.(OsCpn60alpha1) (Mus musculus) PubMed

 12259.

the overexpression of either OsASR1 or OsASR3 in transgenic rice plants increased their tolerance to drought and cold stress. (ASR1 and ASR3) (Mus musculus) PubMed

 12260.

Calpain2 activation through the Wnt/Ca(2+) pathway and Dishevelled can modulate convergent extension movements. [Calpain2] (Mus musculus) PubMed

 12261.

MFS1 gene plays an important role in the regulation of spikelet meristem determinacy and floral organ identity.[MFS1] (Mus musculus) PubMed

 12262.

Collapsed abnormal pollen-1 gene is involved in pollen development.[Collapsed abnormal pollen-1] (Mus musculus) PubMed

 12263.

A single-nucleotide polymorphism-6 in the OsLG1 regulatory region led to a compact panicle architecture in cultivars during rice domestication. [OsLG1] (Mus musculus) PubMed

 12264.

both OsERG1 and OsERG3 proteins exhibit oligomerization properties (PAGE) and glutaraldehyde cross-linking experiments. in vitro phosphorylation assays reveal the phosphorylation of OsERG1 and OsERG3 by OsCDPK5.(OsERG1 and OsERG3, OsCDPK5.) (Mus musculus) PubMed

 12265.

After NOTCH1 knockdown and TGFB1 stimulation, rabbit mesenchymal stem cells expressed higher levels of proteoglycan and collagen II. (Mus musculus) PubMed

 12266.

Host-induced gene silencing of the sterol 14alpha-demethylase (CYP51) genes is an effective strategy for controlling Fusarium. (Mus musculus) PubMed

 12267.

Reactive oxygen species (ROS) induce senescence in OsGDCH-RNAi plants (SSPs), and transcription factors OsWRKY72 may mediate the ROS-induced senescence. [OsWRKY72; GDCH] (Mus musculus) PubMed

 12268.

extensive molecular dynamics simulations to reveal the structural and dynamic properties of both the apo and Cu(I)-bound versions of the CusB N-terminal region [CusB] (Mus musculus) PubMed

 12269.

The lysis protein A2 of enterobacteria phage Qbeta preferentially binds bacterial MurA liganded with UDP-NAG, thereby preventing catalysis by occluding PEP from accessing the active site.[A2] (Mus musculus) PubMed

 12270.

Several endoplasmic reticulum-quality control (ER-QC) proteins including stromal-derived factor 2 (SDF2) co-purified with XA21. [XA21; SDF2) (Mus musculus) PubMed

 12271.

OsDET1 mutation in Gc mutant increases chlorophyll (Chl) content in rice, which might be fundamental for enhanced photoresponsiveness. [Oryza sativa indica; OsDET1] (Mus musculus) PubMed

 12272.

TaASR1 functions as a positive factor under drought/osmotic stress, involved in the regulation of reactive oxygen species (ROS) homeostasis by activating antioxidant system and transcription of stress-associated genes. [TaASR1] (Mus musculus) PubMed

 12273.

gamma-tocotrienol showed attenuation of triglyceride through effect on fatty acid synthase, sterol regulatory element-binding transcription factor 1, stearoyl CoA desaturase 1, and carnitine palmitoyl transferase 1A gene expression in Hepa 1-6 cells. [CPT1A] (Mus musculus) PubMed

 12274.

The acquisition of the PB2-701N substitution by H1N1 viruses may result in more severe disease or increase transmission in humans. [PB2] (Mus musculus) PubMed

 12275.

In all, this work highlights how the main core of the Escherichia coli globin ApoHmpH is capable of becoming fully native efficiently, on the sub-millisecond time scale. [HmpH] (Mus musculus) PubMed

 12276.

Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid-assisted flavoprotein strategy for regioselective aromatic hydroxylation. (Mus musculus) PubMed

 12277.

Mechanistic studies indicated that NS4B disrupts the interactions between STING/MITA and TBK1, an additional mechanism for HCV evasion of host interferon responses. (Mus musculus) PubMed

 12278.

The highly variable region (HVR) of HCpro in potyviruses regulates HCpro conformation and virus-host interactions and suggest that mutation of HVR induces host defense. [HCpro] (Mus musculus) PubMed

 12279.

The focal accumulation of VvMLO3/VvMLO4 and VvPEN1 to the site of attack seems to be required for their opposing functions during powdery mildew attack, because the subcellular localization is correlated with the outcome of attempted penetration. [PEN1] (Mus musculus) PubMed

 12280.

miR-29a mediated Caveolin 2 regulation, modulating the activation state of CDC42, in intestinal Salmonella infection, is reported.[miR-29a] (Mus musculus) PubMed

 12281.

LbAha1 has structural dimensions and flexibility that allow interacting with both N-terminal and middle domains of the LbHsp90.[Aha1, Hsp90] (Mus musculus) PubMed

 12282.

The role of UGT72L1 in proanthocyanidin biosynthesis [UGT72L1] (Mus musculus) PubMed

 12283.

Streptococcus pyogenes protein 0843 contains two leucine-rich repeat domains that mediate interactions with the gp340 receptor. (Streptococcus pyogenes adhesin protein 0843) (Mus musculus) PubMed

 12284.

A Sclerotinia sclerotiorum ortholog of the Magnaporthe grisea peroxisomal peroxisomal carnitine acetyl transferase-encoding gene Pth2 is required for virulence-associated host colonization. [Ss-pth2] (Mus musculus) PubMed

 12285.

Pi-hk1 was mapped to a 107-kb region between molecular markers P3586 and ILP3, and co-segregated with the markers P4098, RM7654, and P4099. [Pi-hk1] (Mus musculus) PubMed

 12286.

PprA, DdrA, and DdrD gene products are components of overlapping processes that make a major contribution to UV resistance. [PprA, DdrA, and DdrD] (Mus musculus) PubMed

 12287.

Addition of potassium to sltA deletion mutants resulted in decreased levels of sterigmatocystin production. [SltA] (Mus musculus) PubMed

 12288.

Xanthomonas campestris pv. vesicatoria virulence factor Fha1 interacts with CaHIR1, induces susceptibility cell death, and suppresses PR gene expression in host plants. (Mus musculus) PubMed

 12289.

A single point mutation was found in the DHODH coding sequence of drug resistant clones that change a conserved Asn into Ser in the dihydroorotate binding site.[DHODH] (Mus musculus) PubMed

 12290.

BH1 is an important floral organ development gene. The bh1 mutant produces a curved, beak-like lemma and palea. (Mus musculus) PubMed

 12291.

OsSRT1 is directly involved in transposable element repression [SRT1] (Mus musculus) PubMed

 12292.

the role of PfAtg7 in erythrocytic stage [Atg7] (Mus musculus) PubMed

 12293.

biochemical characterization of Agn1p [Agn1p] (Mus musculus) PubMed

 12294.

FgAtf1 may be the most important transcription factor regulated by FgOS-2. [FgAtf1; FgOS-2] (Mus musculus) PubMed

 12295.

These findings suggest that GlNR2 is an active nitroreductase with a mode of action different from that of GlNR1.[GlNR2] (Mus musculus) PubMed

 12296.

ICP22 but not US1.5 is required for efficient acute replication in mice and VICE domain formation.[US1.5] (Mus musculus) PubMed

 12297.

[RssB, substrain not shown] mutations in the RssB C-terminal PP2C-like domain, led to activation of RssB function. (Mus musculus) PubMed

 12298.

ICP35 is translated cap independently by an IRES element located in the 5' untranslated region of icp35. [ICP35] (Mus musculus) PubMed

 12299.

TRAIL expression by osteoclast-like cells is increased in the presence of RANKL and after scraping; DcR2 expression peaks at 24 hours, and and decreases at 5 days; DR5 expression peaks at 5 days [DcR2] (Mus musculus) PubMed

 12300.

Targeted mutations of histidine residues confirmed the importance of the zinc binding crevice for the structure and function of the Lmb adhesin.[Lmb] (Mus musculus) PubMed

 12301.

The findings indicate that protease 2A-mediated cleavage of dystrophin is critical for Coxsackievirus propagation, enteroviral-mediated cytopathic effects, and the development of cardiomyopathy (protease 2A). (Mus musculus) PubMed

 12302.

the fission yeast IDE homologue (Iph1) modulates cellular sensitivity to endoplasmic reticulum (ER) stress in a manner dependent on TORC1.[Iph1] (Mus musculus) PubMed

 12303.

XALc_0557 has a predicted OmpA N-terminal outer membrane channel (OMC) domain and an OmpA C-like domain. XALc_0557 complemented M468 for all phenotypes tested: pathogenicity, resistance to SDS, and survival endophytically and epiphytically. (Mus musculus) PubMed

 12304.

Mannitol utilization is required for protection of Staphylococcus aureus from human skin antimicrobial fatty acids via expresion of Mtl. [Mtl] (Mus musculus) PubMed

 12305.

Nonstructural 5A protein (NS5A) of hepatitis C virus interacts with pyruvate carboxylase and modulates viral propagation. [NS5A] (Mus musculus) PubMed

 12306.

PakB plays a critical role in regulating the cellular functions of Abp1, which are mediated largely by its SH3 domain. [Abp1] (Mus musculus) PubMed

 12307.

OsERF4a is a positive regulator of shoot growth and water-stress tolerance in rice.OsERF4a could work by suppressing a repressor of the defense responses and/or by controlling the expression of genes located on chromosome 11.[OsERF4a] (Mus musculus) PubMed

 12308.

These results demonstrate that IPF19998 played an important role in Candida albicans biofilms formation and intracellular redox homeostasis.[IPF19998] (Mus musculus) PubMed

 12309.

Data indicate that the BOR1 genes TaBOR1.1, TaBOR1.2 and TaBOR1.3. from the hexaploid genome of wheat are the B efflux transporters: [TaBOR1.1, TaBOR1.2 and TaBOR1.3.] (Mus musculus) PubMed

 12310.

inositol-requiring enzyme 1alpha (IRE1alpha)is not required for germ layer formation but for gut developmen in Xenopus lavies and it may function via XBP1-dependent pathway.[Inositol requiring enzyme 1alpha] (Mus musculus) PubMed

 12311.

The findings support and extend a previously proposed model for relieving heat-stable nucleoid-structuring protein-mediated repression by VirB (VirB). (Mus musculus) PubMed

 12312.

Data suggest PsaR/MntR is stable homodimer irrespective of metallation state and exhibits 2 pairs of divalent metal (Mn/Zn) binding sites (4 per dimer) that are functionally/structurally distinct. [psaR, MntR; Mn-dependent transcriptional regulator] (Mus musculus) PubMed

 12313.

The activities of Calpain and PLA2 on the muscle tissue of the bladders were analyzed.[PLA2] (Mus musculus) PubMed

 12314.

Data suggest that N/C-terminal extrinsic domains of PufX promote dimerization of reaction center-light harvesting complex 1 (RC-LH1) by interacting with corresponding domains of another peptide from other half. [pufX; intrinsic membrane pufX protein] (Mus musculus) PubMed

 12315.

3HB6H does not exhibit substrate inhibition on the flavin oxidation step, a common characteristic found in most ortho-hydroxylation enzymes. The apparent kcat of 3HB, NADH, and oxygen is 6.49 +/- 0.02 s(-1). (3-hydroxybenzoate 6-hydroxylase, 3HB6H) (Mus musculus) PubMed

 12316.

The soluble transmissible gastroenteritis virus spike showed binding to aminopeptidase N but had no detectable sialic acid binding activity.[spike protein] (Mus musculus) PubMed

 12317.

Consequently, our results demonstrated that the cytoplasmic expression system is efficient for the production of reteplase protein in prokaryote systems and a high amount of reteplase was obtained from the expressed proteins in the form of IBs (Mus musculus) PubMed

 12318.

Authors now report that the FabK enoyl-acyl carrier protein reductase is indeed poorly expressed and that the expression defect is at the level of translation rather than transcription.[FabK] (Mus musculus) PubMed

 12319.

fibrinogen binding by glycoproteins Srr1 and Srr2 of Streptococcus agalactiae [Srr1][Srr2] (Mus musculus) PubMed

 12320.

Crystal structure and site-directed mutagenesis of 3-ketosteroid Delta1-dehydrogenase from Rhodococcus erythropolis SQ1 explain its catalytic mechanism. (Delta(1)-KSTD1) (Mus musculus) PubMed

 12321.

capnophilic growth restriction could be caused by a single amino acid substitution in the MurF UDP-MurNAc-pentapeptide synthetase that is essential for cell wall biogenesis [MurF] (Mus musculus) PubMed

 12322.

TbMLP (Mucolipin-like protein) is confined to the endomembrane system, and appears to play a major role in iron metabolism within the parasite. [TbMLP] (Mus musculus) PubMed

 12323.

This study demonstrated specific patterns of alimentary and neuronal transcription of AeNAT5 in mosquito larvae that is collateral with the indispensable function of this transporter in mosquito development (NAT5). (Mus musculus) PubMed

 12324.

uap1 is an essential gene for A. fumigatus growth; uap1 is important for cell wall ultrastructure, integrity and synthesis (Mus musculus) PubMed

 12325.

the cytoprotective RhoB response is not only evoked by bacterial protein toxins inactivating Rho/Ras proteins but also by the Rac1-activating toxin CNF1.[CNF1] (Mus musculus) PubMed

 12326.

STM2215 has cyclic di-GMP phosphodiesterase activity and is necessary for colonization of BALB/c mice but not macrophages. [STM2215] (Mus musculus) PubMed

 12327.

(Akt proto ongogene protein) The Akt/PI3K survival pathway is activated in the non-ischemic adjacent zone following myocardial infarction. (Mus musculus) PubMed

 12328.

Inhibiting PHD or knocking down VHL rescues Methyl tert-butyl ether induced vascular lesions. [HIF Prolyl-4-Hydroxylases] (Mus musculus) PubMed

 12329.

The high ATPase activity in the presence of hydrophobic, long chain detergents revealed that Sav1866, despite its lower basal catalytic efficiency, is a more efficient floppase for lipidlike amphiphiles than P-glycoprotein. (Sav1866) (Mus musculus) PubMed

 12330.

These findings strongly suggest that the additional transmembrane segments of the Streptomyces coelicolor Rieske protein mediate hydrophobic interactions with one or both of the cytochrome subunits.[Rieske protein] (Mus musculus) PubMed

 12331.

Authors speculate that the SMU.746-SMU.747 complex is responsible for amino acid transport, and discuss its possible role in colonization and survival in the oral environment.[SMU.746, SMU.747] (Mus musculus) PubMed

 12332.

Overexpression of the GS gene in rice modulated the expression of enzymes responsible for membrane peroxidation that may result in plant death. [glutamine synthetase] (Mus musculus) PubMed

 12333.

These observations suggest that the cofactor coordinated by these three cysteine residues in the ArnR protein plays a critical role in the NO-responsive expression of the narKGHJI operon and the hmp gene.[ArnR] (Mus musculus) PubMed

 12334.

Replacement of the conserved proline residue at position 443 in PulD by leucine increased the apparent size of the pore.[PulD] (Mus musculus) PubMed

 12335.

PgtE and other members in the omptin protease family increase human uPA activity by a specific single cut of the catalytic chain of scuPA (Mus musculus) PubMed

 12336.

A total of 57 interface residues of the small and large ADP-glucose pyrophosphorylase subunits take part in the assembly of a functional enzyme. [ADP-glucose pyrophosphorylase] (Mus musculus) PubMed

 12337.

Leucine-rich repeat domains control the activation of the potato immune receptors Rx1 and Gpa2. [Rx1] [Gpa2] (Mus musculus) PubMed

 12338.

the transient kinetics of the oxidation reaction between DsbASH,SH and DsbBS-S,S-S [DsbA][DsbB] (Mus musculus) PubMed

 12339.

CcpE is a major direct positive regulator of the TCA cycle gene citB (Mus musculus) PubMed

 12340.

proton-mediated conformational changes in an acid-sensing ion channel [ASIC1a] (Mus musculus) PubMed

 12341.

the A variant was the more favorable allele associated with significantly increased seedling biomass and water-soluble carbohydrates. [TaSnRK2.8] (Mus musculus) PubMed

 12342.

G2, a novel subpellicular network protein, plays an essential role in morphogenesis without influencing tensile strength. [G2] (Mus musculus) PubMed

 12343.

both calcium and alkalinity trigger CrzA nuclear localization and activation [Crza] (Mus musculus) PubMed

 12344.

Study describes a nuclear RNA-processing network in fission yeast with a core module comprising the Mtr4-like protein, Mtl1, and the zinc-finger protein, Red1. The Mtl1-Red1 core promotes degradation of mRNAs and noncoding RNAs and associates with different proteins to assemble heterochromatin via distinct mechanisms.[Mtl1] (Mus musculus) PubMed

 12345.

The study demonstrates a dimerization of the coiled coil domain and a hydrolytic activity of the esterase domain of the ORF1p from the Danio rerio ZfL2-1 element (ORF1p). (Mus musculus) PubMed

 12346.

His206 and Cys107 act as the proximal and distal axial ligands in ferric Leishmania major pseudoperoxidase (LmPP). [LmPP] (Mus musculus) PubMed

 12347.

Sp1 binding element in Rta promoter strongly correlates with cellular permissivity for viral replication. [Rta] (Mus musculus) PubMed

 12348.

Deletion of rpaA abrogates gene expression rhythms globally and arrests cells in a dawn-like expression state and show that the response regulator RpaA serves as the master regulator of the cyanobacterial circadian clock. [RpaA] (Mus musculus) PubMed

 12349.

Suggest that in neurospora frequency-interacting RNA helicase (FRH) acts nonenzymatically to stabilize intrinsically disordered clock protein frequency (FRQ). (Mus musculus) PubMed

 12350.

This is the first study to show association between PfEMP-1 subtype and disease outcome by direct analysis of parasites proteome.[PfEMP-1] (Mus musculus) PubMed

 12351.

We have determined the crystal structure of the ROP18 kinase domain, which is inconsistent with a previously proposed autoinhibitory mechanism of regulation. phenotype. (Mus musculus) PubMed

 12352.

NAL2/3 expression regulates leaf width.[NAL2, NAL3] (Mus musculus) PubMed

 12353.

Two histone H4 mutants-H4-R36A and H4-K31E-alter the association pattern of Spt16 across transcribed genes.[Spt16] (Mus musculus) PubMed

 12354.

SSEA4 expression is required for pig induced pluripotent stem cells to differentiate into neurons, astrocytes, and oligodendrocytes.[SSEA4] (Mus musculus) PubMed

 12355.

A lactose permease (Trire2:3405)in Trichoderma reseei is essential for lactose utilization. [lactose permease Trire2:3405] (Mus musculus) PubMed

 12356.

Rot affects autolysis by directly regulating autolysins LytM and LytN, and, via a regulatory system, LrgAB.[Rot] (Mus musculus) PubMed

 12357.

The structure of an active E. coli ribosome-channel complex demonstrates that the nascent chain opens the channel, causing mostly rigid body movements of the amino- and carboxy-terminal halves of SecY. [SecY] (Mus musculus) PubMed

 12358.

Data suggest that MCK2, by forming a complex with glycoprotein H, promotes macrophage infection (virus internalization); mutants lacking both, glycoprotein O and MCK2 are not able to produce infectious virus. [MCK2; murine cytomegalovirus chemokine] (Mus musculus) PubMed

 12359.

A 3d TNF-alpha isoform (TNF-alpha3) has only low identities to known trout molecules. Expression was lower except in macrophages. It is the most responsive gene at early time points after LPS stimulation (TNF-alpha3). (Mus musculus) PubMed

 12360.

A high copy number suppressor screen was performed to search for genes that, when overexpressed, suppress the synthetic lethality between elg1Delta and srs2Delta mutants.[SRS2] (Mus musculus) PubMed

 12361.

Data suggest that M029 (an RNA-binding protein) plays pivotal role in determining cellular tropism of Myxoma virus in all mammalian cells tested; human protein kinase R/EIF2AK2 and RNA helicase A/DHX9 are two binding partners of M029. [M029] (Mus musculus) PubMed

 12362.

OsJAR1 contributes mainly to stress-induced JA-Ile production by the use of an osjar1 Tos17 mutant [JAR1] (Mus musculus) PubMed

 12363.

MCS made no contribution to citric acid production from glucose in A. niger WU-2223L [MCS] (Mus musculus) PubMed

 12364.

Data suggest formation of gH/gL/UL128/UL130/UL131A complex links activation of integrin/Src/paxillin-mediated signaling pathway to viral internalization into target human monocytes but not to viral internalization into human fibroblasts. [UL128] (Mus musculus) PubMed

 12365.

Data suggest that Ssph2 significantly enhances human NOD1- (nucleotide-binding oligomerization domain-containing protein 1-) mediated secretion of interleukin-8; SspH2 interacts with and ubiquitinates NOD1. [Ssph2; ubiquitin ligase effector] (Mus musculus) PubMed

 12366.

Data suggest ClbA, the phosphopantetheinyl transferase encoded on high pathogenicity island with polyketide synthases, participates in biosynthesis of both enterobactin (siderophore) and colibactin (genotoxin). [ClbA; phosphopantetheinyl transferase] (Mus musculus) PubMed

 12367.

Data suggest that conserved tandem repeats in BAD1 are related to virulence, harbor motifs that bind heparin, and are needed for suppression of mouse T-cell activation via a CD47- (thrombospondin receptor-) dependent mechanism. [BAD1/adhesin-1] (Mus musculus) PubMed

 12368.

Analysis of crystal structure of Zn fingers 3-5 of Chaetomium thermophilum Nab2 bound to polyadenosine RNA establishes the structural basis for the molecular recognition of adenosine ribonucleotides (Nab2). (Mus musculus) PubMed

 12369.

work reveals an unanticipated role of RecA bundles in channelling the movement of the DNA double-stranded break ends, thereby facilitating the long-range homology search that occurs before the strand invasion and transfer reactions [RecA] (Mus musculus) PubMed

 12370.

LukGH did not prime human neutrophils for increased production of reactive oxygen species nor did it enhance binding and/or uptake of S. aureus. It promoted the release of neutrophil extracellular traps. LukGH.LukAB. (Mus musculus) PubMed

 12371.

CA-11 from genomic DNA of the bat Megaderma lyra, was amplified. To elucidate the gene structure, PCR products were sequenced and their sequences were compared with genomic and mRNA sequences known from human and domestic pig.[CA-11] (Mus musculus) PubMed

 12372.

This study isolated the SBEIII cDNA sequence (3,780 bp), designated TaSBEIII.[TaSBEIII] (Mus musculus) PubMed

 12373.

The C-terminal linker of Escherichia coli FtsZ functions as an intrinsically disordered peptide. [FtsZ] (Mus musculus) PubMed

 12374.

YidC can act as a post-translational insertase, a finding which could explain the absence of a ribosome binding domain on YidC.[YidC] (Mus musculus) PubMed

 12375.

GshT primes glutathione import via the L-cystine ABC transporter TcyBC, a membrane permease. [GshT, TcyBC] (Mus musculus) PubMed

 12376.

LiaR regulates expression of genes involved in microbial defence against host antimicrobial systems including genes functioning in cell wall synthesis, pili formation and cell membrane modification. [liaR] (Mus musculus) PubMed

 12377.

regulation of the RNA nterference (RNai) machinery by Hsp90 may have evolved at the same time as ancestral RNAi.[HSP90] (Mus musculus) PubMed

 12378.

Protein-protein interaction data revealed interaction between the subunits of GlVPS35 and the cytosolic domain of the hydrolase receptor Giardia lamblia vacuolar protein sorting.[VPS35] (Mus musculus) PubMed

 12379.

The 56 kDa encoded by wPip_0282 is associated with sperm transferred to females by Wolbachia infected males. (Mus musculus) PubMed

 12380.

The crystal structure of a truncated SipA protein from group A streptococcus, determined at 1.67A resolution is reported. (Mus musculus) PubMed

 12381.

fhlA regulates the size of the heart chamber by reducing the number of cardiac cells.[fh1A] (Mus musculus) PubMed

 12382.

Downregulation of cell wall-encoding genes in the goa1Delta results in reduced phagocytosis by a macrophage cell line, reduced recognition by macrophage receptors, and decreased expression of cytokines such as IL-6, IL-10 and IFN-gamma. (Mus musculus) PubMed

 12383.

Overexpression of the yeast septin7 ortholog CDC10 also conferred resistance to the negative effects of copper as well as protecting cells from the overexpression of Bax.[CDC10] (Mus musculus) PubMed

 12384.

The first 3D structure and in vivo relevance of a 1-C-Grx from a pathogenic protozoa Trypanosoma brucei. [mitochondrial monothiol glutaredoxin-1] (Mus musculus) PubMed

 12385.

Mass spectrometry of intact protein species revealed a pathway for synthesis of the urease pre-activation complex in which individual hetero-trimer units of the (maltose binding protein -UreD:UreF:UreG)2 complex bind to urease.[UreD,UreF,UreG,urease] (Mus musculus) PubMed

 12386.

ChiB gene is 1,689-bp long with an open reading frame of 1,500 bp and chiC is 1,844 bp with an open reading frame of 1,443 bp. [chiB, chiC] (Mus musculus) PubMed

 12387.

Lpd regulates mesenchymal neural crest cell migration cell autonomously in Xenopus laevis via the Scar/WAVE complex.[Lpd] (Mus musculus) PubMed

 12388.

The involvement of TbPEX4 in TbPEX5 ubiquitination was demonstrated using procyclic PEX4 trypanosomes.[PEX5, PEX4] (Mus musculus) PubMed

 12389.

a structural analysis of the surface exposed domains of PfbA [PfbA] (Mus musculus) PubMed

 12390.

the loss of the Snf1 catalytic subunit impairs the binding of SBF and MBF complexes and the subsequent recruitment of the FACT complex and RNA Polymerase II to promoters of G1-genes.[MBF, SBF, Snf1] (Mus musculus) PubMed

 12391.

Der1 initiates the export of aberrant polypeptides from the endoplasmic reticulum lumen.[Der1] (Mus musculus) PubMed

 12392.

Deletion analysis and site-directed mutagenesis of the csrB and csrC regulatory regions revealed that an 18-bp inverted repeat sequence is required for transcriptional activation of both genes.[csrC] (Mus musculus) PubMed

 12393.

IC138 and IC140 bind directly to microtubules.[IC138, IC140] (Mus musculus) PubMed

 12394.

eIF4B and eIF4G jointly stimulate ATP hydrolysis and RNA unwinding by eIF4A and favor the formation of the closed eIF4A conformer.[eIF4A, eIF4B, eIF4G] (Mus musculus) PubMed

 12395.

20-Hydroxyecdysone-induced transcriptional activity of FoxO upregulates brummer and acid lipase-1 and promotes lipolysis in fat body. [acid lipase-1 , FoxO] (Mus musculus) PubMed

 12396.

FtsA-dependent recruitment of FtsZ polymers to supported membranes, where both proteins self-organize into complex patterns, is reported.[FtsA, FtsZ] (Mus musculus) PubMed

 12397.

Mdm10's presence in both unikonts and bikonts indicates an introduction at an early time point in eukaryotic evolution.[Mdm10] (Mus musculus) PubMed

 12398.

PfCRT has a dual role in chloroquine resistance, facilitating both efflux of harmful chloroquine and influx of beneficial glutathione. [P. falciparum chloroquine resistance transporter] (Mus musculus) PubMed

 12399.

A hyperactive CiaRH system prevents competence development by csRNA-dependent post-transcriptional repression of CSP production. [CSP] (Mus musculus) PubMed

 12400.

Panton-Valentine leukocidin is an important virulence factor that enables the bacteria to produce necrotizing skin infections by allowing them to escape from endosomes, replicate intracellularly, and induce apoptosis. (Mus musculus) PubMed

 12401.

Data indicate that quinoline N-hydroxylating cytochrome P450 RauA high binding affinity to the aurachin RE intermediate: [RauA] (Mus musculus) PubMed

 12402.

OsVHA-A takes part in regulating stomatal density and opening [VHA-A] (Mus musculus) PubMed

 12403.

the functional and structural effects triggered by modification of C222 [TIM] (Mus musculus) PubMed

 12404.

Authors suggest that the methylene group of the chorismate enol ether takes up a proton from an active-site glutamic acid residue, thereby initiating chorismate hydrolysis by chorismatase FkbO.[FkbO] (Mus musculus) PubMed

 12405.

These data show that ICP may be important in regulating proteolytic processes during blood-stage development, and is likely playing a role in liver stage-hepatocyte interactions at the time of exoerythrocytic merozoite release.[ICP] (Mus musculus) PubMed

 12406.

The results showed that S. gordonii V2016 expressed 3 primary alcohol dehydrogenases, AdhA, AdhB and AdhE, which all oxidize ethanol to acetaldehyde, but their preferred substrates were 1-propanol, 1-butanol and ethanol, respectively. [AdhA, AdhB, AdhE] (Mus musculus) PubMed

 12407.

The ae mutant starch granule population is heterogeneous. [ae] (Mus musculus) PubMed

 12408.

curvature and shape of filament on lipid surface [FtsZ] (Mus musculus) PubMed

 12409.

frataxin depletion involves drastic metabolic remodeling governed by Adr1 and Cth2.[Frataxin, Cth2, Adr1] (Mus musculus) PubMed

 12410.

the growth of Escherichia coli LJ110 and of isogenic derivatives, mutated in components of the PTS(Ntr), on different carbon sources, is reported.[EIIA(Ntr)] (Mus musculus) PubMed

 12411.

study demonstrated that the presence of babA2 may be associated with increased risks for peptic ulcer disease, especially duodenal ulcer, in western countries [babA2] (Mus musculus) PubMed

 12412.

Data using mutant recombinant proteins suggest that biocatalysis and substrate specificity of NPP are dependent on specific residues in the substrate/cofactor binding pockets. [NPP; phosphodiesterase-nucleotide pyrophosphatase] (Mus musculus) PubMed

 12413.

Data suggest that manganese-dependent formiminoglutamase exhibits manganese ion binding at an asparagine residue in the binding site and a disulfide linkage (C35/C242) in the active site. [FIGase; formiminoglutamase] (Mus musculus) PubMed

 12414.

Up-regulation of Raf-MEK-ERK pathway by HCV E2 via L-SIGN provides new insights into signaling cascade of L-SIGN [E2] (Mus musculus) PubMed

 12415.

Suggest recombinant hepatitis C virus core protein as hepatitis C vaccine capable of stimulating cytokine secretion in immunized mice. (Mus musculus) PubMed

 12416.

Xenopus laevis XHMG-AT-hook protein exists in three isoforms. Isoforms 1 and 3, but not isoform 2, are expressed throughout the entire development of Xenopus, both in the maternal and zygotic phase.[Xhmg-at-hook1]; [Xhmg-at-hook2]; [Xhmg-at-hook3] (Mus musculus) PubMed

 12417.

A trimeric beta-barrel model for Chlamydia trachomatis isolate CS-362-07 MOMP (ompA)contains conserved and novel elements of Gram-negative bacterial porins. [ompA] (Mus musculus) PubMed

 12418.

the spatial and molecular determinants of IncA's fusogenic and inhibitory functions, were identified.[IncA] (Mus musculus) PubMed

 12419.

the twin-cysteine motif plays a role in Env trimer stabilization in Simian immunodeficiency virus.[gp120] (Mus musculus) PubMed

 12420.

the purification, in vitro characterization, 2.1-A crystal structure, and functional assignment of YfdE, is reported.[YfdE] (Mus musculus) PubMed

 12421.

the substrate promiscuity of Hms is characterized in order to assess its potential for the biosynthesis of chiral alpha-hydroxy acids.[Hms] (Mus musculus) PubMed

 12422.

A higher binding efficiency to chondroitin sulfate A rather than reduced antigenicity might provide a biological advantage to parasites with high parasite density signatures in VAR2CSA. [VAR2CSA] (Mus musculus) PubMed

 12423.

TbSCD6 is not required for the formation of starvation-induced granules in trypanosomes, and it does not form a complex with the helicase Dhh1.[SCD6/rap55 protein, Trypanosoma brucei] (Mus musculus) PubMed

 12424.

CDPK3 is a protein of 485 amino acids and predicted to have a protein kinase domain at the N-terminus and four EF-hand motifs at the C-terminus. [CDPK3] (Mus musculus) PubMed

 12425.

Data suggest that modifying specific residues in catalytic pocket of KDNase (A. fumigatus) to resemble sialidase (Micromonospora viridifaciens) yields substrate specificity/activity resembling sialidase. [KDNase; deaminoneuraminate hydrolase] (Mus musculus) PubMed

 12426.

gp49, the virion-associated peptidoglycan hydrolase from Staphylococcus aureus phage 11, is not essential for phage growth but stabilizes the viral particles.[gp49] (Mus musculus) PubMed

 12427.

These findings show a causal linkage between the acetylation of lysine residue 14 of histone H3 and the transcription and product formation of secondary metabolite gene clusters.[histone H3] (Mus musculus) PubMed

 12428.

Data suggest Zea mays cells in culture as calli exhibit insulin-like growth factor (ZmIGF) and a putative insulin-like receptor (ZmILR); cell proliferation appears to depend on activation of ZmIGF/ZmILR signaling. [ZmIGF; insulin-like growth factor] (Mus musculus) PubMed

 12429.

The activity of the rpsO-pnp promoters increased during cold shock at 10 degrees . [rpoS][pnp][two gene links] (Mus musculus) PubMed

 12430.

Mutations in the ORF2a/ORF2b overlapping region overcome the eIF(iso)4G-mediated rice resistance. [ ORF2a, ORF2b] (Mus musculus) PubMed

 12431.

Data indicate that the O-methyltransferases (Bx10a-c) catalyzing the conversion of DIMBOA-Glc to HDMBOA-Glc were named as Bx10a (GRMZM2G311036), Bx10b (GRMZM2G336824), and Bx10c (GRMZM2G023325): [Bx10a, Bx10b & Bx10c] (Mus musculus) PubMed

 12432.

G-protein subunits play role in primary metabolism during vegetative growth.[Gna1,Gba1, Gga1] (Mus musculus) PubMed

 12433.

Studies suggested that the omp product was involved in the Cu(II) tolerance of Sinorhizobium meliloti [omp] (Mus musculus) PubMed

 12434.

Essential role of the Transient Receptor Potential sub-family A1 (TRPA1) channel in mediating larval thermal-induced locomotion and thermal preference. [AgTRPA1] (Mus musculus) PubMed

 12435.

Data indicate that salt-responsive ERF1 (SERF1), a transcription factor shows a root-specific induction upon salt and hydrogen peroxide (H2O2) treatment: [SERF1] (Mus musculus) PubMed

 12436.

analysis of N. gruberi thiaminase I structure and kinetics [thiaminase I] (Mus musculus) PubMed

 12437.

structural and biochemical characterization of the Tet-like protein from the amoeboflagellate Naegleria gruberi [Tet1] (Mus musculus) PubMed

 12438.

The data confirm that adenine deaminase (AHH) plays the dominant role in adenine metabolism in Leishmania donovani, although adenine phosphoribosyltransferase (APRT) alone is also sufficient for salvage.[AAH, APRT] (Mus musculus) PubMed

 12439.

Knocking out EBR1 in F. graminearum PH-1 caused reduction of both radial growth and virulence.[EBR1] (Mus musculus) PubMed

 12440.

Antibiotic pressure does not induce loss of the cag pathogenicity island, but it can lead to genetic rearrangements within the 3' region of cagA. (Mus musculus) PubMed

 12441.

Des1, 2 and 3 are involved in the delta-6 desaturation pathways for polyunsaturated fatty acid biosynthesis. [Des1, Des2 and Des3] (Mus musculus) PubMed

 12442.

These results demonstrate that Bcr1 regulated opaque cell filamentation is dependent on the cAMP-signalling pathway.[Bcr1] (Mus musculus) PubMed

 12443.

The combination of gp120 and methamphetamine also induced CYP2E1 expression.[gp120] (Mus musculus) PubMed

 12444.

E8;E2C repressor limits viral transcription and replication throughout the complete life cycle of HPV16. [E8] (Mus musculus) PubMed

 12445.

A comparison of the E. coli and S. enterica AraC regulons, coupled with a bioinformatic analysis, reveals a conserved regulatory network across the family Enterobacteriaceae comprised of 10 genes associated with arabinose transport and metabolism.[AraC] (Mus musculus) PubMed

 12446.

The rcn1 rcn11 phenotype suggests that RCN11 acts on vegetative growth independent of RCN1/OsABCG5. [RCN11] (Mus musculus) PubMed

 12447.

WSSV-miR-66 and WSSV-miR-68 targeting virus genes promote virus infection in shrimp. [WSSV-miR-66, WSSV-miR-68] (Mus musculus) PubMed

 12448.

Adenovirus death protein (ADP) is required for lytic infection of lymphocytes. [ADP] (Mus musculus) PubMed

 12449.

a developmental regulator of Caulobacter crescentus, SpmX, is co-opted in the genus Asticcacaulis to specify stalk synthesis either at the subpolar or bilateral positions [SpmX] (Mus musculus) PubMed

 12450.

During hyphal elongation, active Cdc42 remained tightly restricted to the hyphal tip, whereas active Rho1 was broadly associated with the apex and subsequently recruited to the cell division site.[Cdc42, Rho1] (Mus musculus) PubMed

 12451.

BCAM0224 is a multifunctional adhesin endowed with remarkable binding properties, which may represent a general mechanism among trimeric autotransporter adhesins for strengthening bacterial adhesion.[BCAM0224 in strain K56-2] (Mus musculus) PubMed

 12452.

The aim of this study was to characterize immunohistochemically 18 cases of canine haemangiopericytoma using tumour endothelial marker (TEM)-1 and new glue (NG)-2 (Mus musculus) PubMed

 12453.

The genomic region surrounding CYP79D3 contains genes CYP736A2 and UGT85K3. In combination with CYP79D3, these genes encode the enzymes that constitute the entire pathway for cyanogenic glucoside biosynthesis. [CYP79D3,CYP736A2, and UGT85K3] (Mus musculus) PubMed

 12454.

FadA binds to E-cadherin, activates beta-catenin signaling, and differentially regulates the inflammatory and oncogenic responses.[FadA] (Mus musculus) PubMed

 12455.

This approach enabled identification of the loci asnO and ngg by their reduced ability to grow on increased NaCl concentrations, likely due to their inability to produce the osmoprotectant N-acetylglutaminylglutamine (NAGGN).[ngg] (Mus musculus) PubMed

 12456.

In the MTIP:anti-MTIP complex the MyoA-binding groove in MTIP-D3 is considerably less accessible than when occupied by the MyoA helix, due to a shift of two helices.[MTIP] (Mus musculus) PubMed

 12457.

Vibrio cholerae encodes three putative periplasmic proteins, here denoted ShyA, ShyB, and ShyC, that contain both PG binding and M23 family peptidase domains.[ShyA, ShyB, and ShyC] (Mus musculus) PubMed

 12458.

Combined, these results demonstrate a primary mechanism of K(+) uptake in S. aureus and a role for the KtrA, KtrB and KtrD system in pathogenesis.[KtrA, KtrB and KtrD] (Mus musculus) PubMed

 12459.

(AvrBs3) The crystal structure of AvrBs3 is presented in complex with its target DNA sequence revealing a new mode of interaction with the initial thymine of the target sequence, analysis of binding specificity, and thermodynamic properties. (Mus musculus) PubMed

 12460.

pb9 is located in the upper part of the cone of the T5 tail tip, at the end of the tail tube. [pb9] (Mus musculus) PubMed

 12461.

Authors show that Qrr sRNAs also base-pair with and activate translation of the mRNA of a diguanylate cyclase, Vca0939; relieving an inhibitory structure in vca0939 that occludes the ribosome binding site.[Vca0939 in strain BH2126] (Mus musculus) PubMed

 12462.

RrmA mediates both stabilization and destabilization and the specificity of the signals transduced is transcript dependent, suggesting it acts in consort with other factors which differ between transcripts.[RrmA] (Mus musculus) PubMed

 12463.

Together, this work supports a role for VeA and MvlA in modifying SAGA/ADA complex activity.[VeA and MvlA] (Mus musculus) PubMed

 12464.

results reveal how Cas9 uses short trinucleotide protospacer adjacent motif (PAM) recognition to quickly identify potential target sites while scanning large DNA molecules, and to regulate scission of double-stranded DNA [Cas9] (Mus musculus) PubMed

 12465.

The activity of the yeast and human dipeptidyl peptidase III were examined.[DPP3] (Mus musculus) PubMed

 12466.

Tryptamine increase through the suppression of tryptamine 5-hydroxylase (T5H) plays an important signaling role in triggering melatonin biosynthesis in rice. (Mus musculus) PubMed

 12467.

LAP has a broad substrate range, including activity against the dipeptide cysteine-glycine, and that leucine is not the primary target of LAP.[LAP] (Mus musculus) PubMed

 12468.

We conclude that decreased expression of melatonin synthesizing enzymes, AA-NAT and ASMT, in patients with symptomatic H. pylori infection returns to normal level after H. pylori eradication. (Mus musculus) PubMed

 12469.

Both the lack of the functionally redundant FHA-RING ubiquitin ligases Dma1 and Dma2 and moderate Dma2 overproduction affect actomyosin ring contraction as well as primary septum deposition.[Dma1, Dma2] (Mus musculus) PubMed

 12470.

Data suggest that Pho92 regulates cellular phosphate metabolism and Pho4 expression at post-transcriptional level via regulation of mRNA stability by phosphate-dependent binding to 3-prime-untranslated region. [Pho92; phosphate transport protein 92] (Mus musculus) PubMed

 12471.

Here, authors demonstrate that one of the three respiratory nitrate reductases, Nar-1, synthesized by Streptomyces coelicolor is functional exclusively in spores.[Nar-1] (Mus musculus) PubMed

 12472.

These and other data suggest that association of DSB-2 with chromatin is an indicator of competence for DSB formation, and that cells respond to a deficit of CO-competent recombination intermediates by prolonging the DSB-competent state (Mus musculus) PubMed

 12473.

The structure of ferredoxin-NADP(H) reductase, FPR, from the plant pathogen Xanthomonas axonopodis pv. citri, is reported.[FPR] (Mus musculus) PubMed

 12474.

PmrA/PmrB two-component system regulated the lipopolysaccharide modification genes. [PmrA][review] (Mus musculus) PubMed

 12475.

ras1Delta mutants accumulate defects in polarized growth, cytokinesis, and cell cycle progression. We demonstrate that the ras1Delta defects in thermotolerance and mating can be largely explained by the compromised activity of four downstream Rho-GTPases (Mus musculus) PubMed

 12476.

The present study describes development of robust homology model of Leishmania donovani adenosine kinase to forecast interaction phenomenon with inhibitory molecules using structure-based drug designing strategy.[Adenosine kinase] (Mus musculus) PubMed

 12477.

TRX2 could be deleted, with knockout parasites displaying reduced grow-rates, both in vivo and in vitro, and reduced capacity to cause severe disease in a cerebral malaria model.[TRX2] (Mus musculus) PubMed

 12478.

Additional positive charges in the phage RuvC binding site apparently stabilize productive interactions with branched structures other than the canonical Holliday junction.[RuvC] (Mus musculus) PubMed

 12479.

the molecular role of MinC [MinC] (Mus musculus) PubMed

 12480.

This study establishes the involvement of prefoldin in transcription elongation, and supports a role for this complex in cotranscriptional histone eviction. (Mus musculus) PubMed

 12481.

Thus, RelP and RelQ are active (p)ppGpp synthases in Staphylococcus aureus that are induced under cell envelope stress to mediate tolerance against these conditions.[RelP, RelQ] (Mus musculus) PubMed

 12482.

Thus, in C. neoformans UVE1 is a key gene regulated in response to light that is responsible for tolerance to UV stress for protection of the mitochondrial genome. (Mus musculus) PubMed

 12483.

14-3-3gamma was expressed in germinal center B cells in vivo and induced in B cells by T-dependent and T-independent primary CSR-inducing stimuli in vitro. 14-3-3 gamma. (Mus musculus) PubMed

 12484.

Authors identified HP1043 an essential homeostatic global regulator (HsrA [for homeostatic stress regulator]).[HsrA] (Mus musculus) PubMed

 12485.

Data from in vitro studies using recombinant proteins suggest Rad18 can enhance transfer of SUMO (small ubiquitin-related modifier) specifically to Lys164 of DNA-bound PCNA (proliferating-cell nuclear antigen). [Rad18; E3 ubiquitin-protein ligase] (Mus musculus) PubMed

 12486.

YPR011cp-mediated mitochondrial transport of adenosine 5'-phosphosulfate occurs in S. cerevisiae under thermal stress conditions.[YPR011c] (Mus musculus) PubMed

 12487.

JAR1 is essential for jasmonoyl-L-isoleucine production in herbivore-attacked, field-grown plants; required for normal seed development [JAR1] (Mus musculus) PubMed

 12488.

Ecb enhances FH acquisition from serum onto staphylococcal surfaces. Ecb & FH enhance mutual binding to C3b & downregulate complement activation. Ecb & FH C-terminal domains 19-20 bind the C3d part of C3b to form a tripartite complex. Ecb. (Mus musculus) PubMed

 12489.

[Rim101] Rim101 protein recognizes a conserved DNA binding motif (Mus musculus) PubMed

 12490.

Antp is a Hox transcription factor that regulates sericin-1 gene expression in the terminal differentiated silk gland of Bombyx mori [antp] (Mus musculus) PubMed

 12491.

PatG was strongly expressed during patulin production (Mus musculus) PubMed

 12492.

These observations indicate that androgen-dependent expression of Bmp7 is required for the bone nodule outgrowth leading to the formation of these secondary sex characteristics in medaka. (Mus musculus) PubMed

 12493.

Based on these observations we propose a model for crossover assurance that acts through DSB-1 to maintain a DSB-permissive state until all chromosome pairs acquire crossover precursors (Mus musculus) PubMed

 12494.

The expression and function of E(spl)1 and E(spl)3, in tribolium was studied.[E(spl)1, E(spl)2] (Mus musculus) PubMed

 12495.

we conclude that BC1 modulates cellulose assembly by interacting with cellulose and affecting microfibril crystallinity (Mus musculus) PubMed

 12496.

we propose that the CF1A-dependent recruitment of RNAP II onto the promoter for reinitiation and the regulation of directionality of promoter-associated transcription (Mus musculus) PubMed

 12497.

Our results suggest that SAG12-1 is a negative regulator of cell death in rice. (Mus musculus) PubMed

 12498.

Double mutant constructions and over-expression experiments suggested that Pab2p and Xrn2p could act in the same pathway whereas Rrp44p appears to act independently (Mus musculus) PubMed

 12499.

Natural haemozoin induces inflammation-mediated expression and release of human monocyte TIMP-1 through p38 MAPK- and NF-kappaB-dependent mechanisms [haemozoin] (Mus musculus) PubMed

 12500.

Overall immune homeostasis was maintained in mice with miR-17-92-deficient Tregs, but it was needed for Treg accumulation & function. Treg-specific loss of miR-17-92 exacerbated experimental autoimmune encephalitis & prevented clinical remission (microRNA-17-92 cluster). (Mus musculus) PubMed

 12501.

Asian crops and straw hull weeds deviate from neutrality at the black hull gene and suggest possible selection on Bh4 during both rice domestication and de-domestication. [Bh4; black hull 4] (Mus musculus) PubMed

 12502.

[ectodysplasin] Because a close correspondence is found between plate phenotype and genotype at a quantitative trait locus tightly linked to the gene ectodysplasin, the evidence for adaptive differentiation is confirmed at neutral marker loci. (Mus musculus) PubMed

 12503.

Results show WASH is required for the maturation of lysosomes to a stage at which hydrolases can be retrieved and reused. (Mus musculus) PubMed

 12504.

S7ORF2 protein gradually accumulates in the host cell during virus replication cycle. [S7ORF2, nuclear export protein} (Mus musculus) PubMed

 12505.

A molecular mechanism of activation of nitrate reductase which involves the pyranopterin moiety of the molybdenum cofactor that is proximal to the [4Fe-4S] cluster, is proposed.[Nitrate reductase] (Mus musculus) PubMed

 12506.

MC159 bound to upstream activators TBK1 and IKKepsilon to inhibit IRF3-controlled luciferase activity. [MC159] (Mus musculus) PubMed

 12507.

These results strongly indicate that OsOSC6 is an alpha- and beta-amyrin synthase.[OsOSC6] (Mus musculus) PubMed

 12508.

The minimum epitope sequence of HBZ recognized by the CD4 T cells from an ATLL patient was RRRAEKKAADVA (HBZ114-125). This peptide was also presented on HLA-DRB1*15:02, recognized by CD4 T cells. HBZ. (Mus musculus) PubMed

 12509.

The first report of a bacterial DNA mimic, SAUGI, that may regulate uracil-DNA glycosylase's functional roles (SAUGI). (Mus musculus) PubMed

 12510.

Structural study of the engagement of the phosphoacceptor strand and the role of aspartate in general acid-base catalysis by polynucleotide kinase (polynucleotide kinase). (Mus musculus) PubMed

 12511.

ROP18 and GRA7 act in a complex to target IRGs by distinct mechanisms that are synergistic [ROP18, GRA7] (Mus musculus) PubMed

 12512.

EBV-encoded miR-BART20-5p inhibits T-bet translation with secondary suppression of p53 in invasive nasal NK/T-cell lymphoma.[miR-BART20-5p] (Mus musculus) PubMed

 12513.

These results provide evidence for an important role of LRT2/OsCYP2 in auxin signaling.[LRT2] (Mus musculus) PubMed

 12514.

DTD functions coordinately with TDR to control tapetal programmed cell death and degeneration in developmental anthers.[DTD, TDR] (Mus musculus) PubMed

 12515.

ligand-induced activation of an immune signaling receptor complex involves both CEBiP (chitin-elicitor binding protein), and Oryza sativa chitin-elicitor receptor kinase-1 [CEBiP, CERK1] (Mus musculus) PubMed

 12516.

hydrogen bond between the amide NH group of Gly541' and the carbonyl of Gly534' in the beta-turn-beta motif is important to catalysis and the importance of disulfide ring size in the catalytic mechanism. (Mus musculus) PubMed

 12517.

our results provide evidence that OsMRE11 performs a function essential for maintaining the normal HR process and inhibiting non-homologous recombination during meiosis. (Mus musculus) PubMed

 12518.

this study determined the x-ray crystal structure of the head domain of EpsH at 1.59A resolution using molecular replacement with the previously reported EpsH structure, 2qv8, as the template. [EpsH] (Mus musculus) PubMed

 12519.

this study reports the crystal structure of a thermostable MnSOD from C. thermophilum. [CtMnSOD] (Mus musculus) PubMed

 12520.

The ability of PvNod22 to suppress protein aggregation contributes to the maintenance of endoplasmic reticulum homeostasis, thus preventing the induction of cell death via UPR in response to oxidative stress during plant-microbe interactions. [nod22] (Mus musculus) PubMed

 12521.

The C-terminus of Wheat streak mosaic virus coat protein (CP) is involved in differential infection of wheat and maize. (Mus musculus) PubMed

 12522.

proteasome is required for SigT degradation by affecting the production of secondary metabolites during cell differentiation [SigT] (Mus musculus) PubMed

 12523.

STING is stable in cancer-derived HEp-2 or HeLa cells infected with wild-type HSV-1 but is degraded in cells infected with mutants lacking the genes encoding functional infected cell protein 0 (ICP0), ICP4, or the US3 protein kinase.[ICP0] (Mus musculus) PubMed

 12524.

Core is capable of up-regulating NANOG expression (Mus musculus) PubMed

 12525.

Protonated LacY binds D-galactopyranosides specifically, inducing an occluded state that can open to either side of the membrane.[LacY] (Mus musculus) PubMed

 12526.

A pairwise interaction screen that confirms a CRL4-like subunit arrangement and further identifies Dos2 as a central component of the complex and recruiter of Stc1, is reported.[Clr4, Dos1] (Mus musculus) PubMed

 12527.

PhoPQ coordinately regulates outer membrane acidic glycerophospholipids with lipid A structure.[PhoP, PhoQ] (Mus musculus) PubMed

 12528.

despite structural homology to its eukaryotic counterparts, Ago functions in host defence by DNA-guided DNA interference [Ago] (Mus musculus) PubMed

 12529.

The data suggest that TaMYB13-1 plays an important role in coordinated upregulation of genes necessary for fructan synthesis and can be used as a molecular tool to improve the high fructan trait.[MYB13-1] (Mus musculus) PubMed

 12530.

Of the three VRN1 loci, winter alleles at Vrn-B1 had the strongest interaction with PPD, delaying heading time by 99.0 degree days under long days.[Ppd-D1] (Mus musculus) PubMed

 12531.

From these results, it is suggested that L-lactate metabolism, which is controlled by LldR, has a buffering function of the pyruvate pool for glutamate production.[LldR] (Mus musculus) PubMed

 12532.

Salmonella enterica serovar Typhi cutF is upregulated during environmental stress. (Mus musculus) PubMed

 12533.

data suggest a mechanism of commitment to gametocytogenesis in Plasmodium consistent with a positive feedback loop involving PbAP2-G that could be exploited to prevent the transmission of this pernicious parasite [AP2-G] (Mus musculus) PubMed

 12534.

findings identify PfAP2-G as a master regulator of sexual-stage development in malaria parasites and mark the first discovery of a transcriptional switch controlling a differentiation decision in protozoan parasites [Ap2-G] (Mus musculus) PubMed

 12535.

Autophagy does not require Golgi traffic, but it is crucially dependent on RabO(RAB1).[Rab1] (Mus musculus) PubMed

 12536.

Polymorphism ss707197675 of dectin-1 is related to susceptibility to nonspecific digestive disorders (NSDD) and increased expression of proinflammatory cytokines, and dectin-1 could be an important candidate gene associated with NSDD in rabbits.[dectin-1] (Mus musculus) PubMed

 12537.

TaRLP1.1 was screened by GeneChip and found to be induced by Puccinia striiformis f. sp. tritici (Pst) specifically in the stripe rust-resistant variety. Knockdown of TaRLP1.1 in stripe rust-resistant plants resulted in increased susceptibility to Pst. (Mus musculus) PubMed

 12538.

Identified and characterised is a mitochondrial transcription factor B homolog in the soil dwelling cellular slime mould Dictyostelium discoideum.[mitochondrial transcription factor B homolog] (Mus musculus) PubMed

 12539.

Unwinding and rewinding by two DNA repair helicases, bacteriophage T4 UvsW and Escherichia coli RecG, are reported.[RecG] (Mus musculus) PubMed

 12540.

By coupling photoaffinity labeling experiments with proteomics and transcriptomics, we identified the likely lipo-chitooligosaccharides - binding protein as LYR3, a lysin motif receptor-like kinase. [LYR3] (Mus musculus) PubMed

 12541.

TgATG4-depleted parasites appear to be defective in the recycling of membrane-bound TgATG8.[TgATG4, TgATG8] (Mus musculus) PubMed

 12542.

afTMEM16, from Aspergillus fumigatus, is a dual-function protein: it is a Ca(2+)-gated channel, with characteristics of other TMEM16 homologues, and a Ca(2+)-dependent scramblase.[afTMEM16] (Mus musculus) PubMed

 12543.

we cloned the catalytic domain of the Oryzias latipes sentrin/SUMO-specific protease 1 (OlSENP1-CD) gene and produced the recombinant OlSENP1-CD protein in Escherichia coli (Mus musculus) PubMed

 12544.

The high-digestible sorghum phenotype is tightly linked to a single-point mutation, rendering the signal peptide of a seed storage protein kafirin resistant to processing.[Kafirin] (Mus musculus) PubMed

 12545.

An extended (0.4 micros) equilibrium molecular dynamics simulation of membrane-embedded, dimeric ClC-ec1, a CLC from Escherichia coli, reveals transient but frequent hydration of the central hydrophobic region by water molecules.[ClC-ec1] (Mus musculus) PubMed

 12546.

WOX5 was primarily expressed in the root and calli induced by auxin and cytokinin, indicating that WOX5 may play a role related to root formation or development and is associated with hormone regulation in somatic embryogenesis. [WOX5] (Mus musculus) PubMed

 12547.

a critical role for the Rpn11 protein in fully assembled 26S proteasomes [Rpn11] (Mus musculus) PubMed

 12548.

pdxA gene affects the pyridoxal-5'-phosphate-mediated flagellar motility function [ pdxA] (Mus musculus) PubMed

 12549.

This study reported on teh mapping of Hild binding across the S. typhimurium genome using chromatin immunoprecipitation-sequencing.[HilD] (Mus musculus) PubMed

 12550.

Data indicate that inactivation of pipX only partially rescued the growth defect observed in the presence of ammonium, indicating the presence of an as yet unknown P(II) (glnB) function(s) required for normal growth: [glnB and PipX] (Mus musculus) PubMed

 12551.

findings demonstrate that glutathione biosynthesis is positively regulated by both LsrB and OxyR in S. meliloti [lsrb] (Mus musculus) PubMed

 12552.

the crystal structure of StTae4 in complex with EcTai4 [Tae4] (Mus musculus) PubMed

 12553.

the crystal structure of StTae4 in complex with EcTai4 [Tai4] (Mus musculus) PubMed

 12554.

DivIVA is phosphorylated in vivo on five sites in the C-terminal part of the protein T304, S309, S338, S344, and S355. [DivIVA] (Mus musculus) PubMed

 12555.

This identification and characterization of the Rht-B2 dwarfing gene will facilitate its utilization in wheat breeding. (Mus musculus) PubMed

 12556.

SaePQ is not needed for SDS-mediated SaeS signaling.[SaeP, SaeQ] (Mus musculus) PubMed

 12557.

Identifies FosB as a primary fosfomycin-modifying pathway of S. aureus and establishes the enzyme as a potential therapeutic target for increased efficacy of fosfomycin against the pathogen.[FosB] (Mus musculus) PubMed

 12558.

A point mutation responsible for resistance to lincosamides, streptogramins A, and pleuromutilins was found within a 1,503-bp gene coding for an ABC transporter named eat(A). [eat(A)] (Mus musculus) PubMed

 12559.

Complete sequence of pSAM7 is presented, an IncX4 plasmid carrying a novel blaCTX-M-14b transposition unit isolated from Escherichia coli and Enterobacter cloacae from cattle. [blaCTX-M-14b] (Mus musculus) PubMed

 12560.

These data suggested that Ebh contributes to the characteristic cell growth and envelope assembly pathways of S. aureus, thereby enabling complement resistance and the pathogenesis of staphylococcal infections. (Mus musculus) PubMed

 12561.

PP2A(Rts1) plays a role in mechanisms that link G1 cyclin accumulation to cell growth.[Rts1] (Mus musculus) PubMed

 12562.

GWL is required not only for meiotic maturation but also for maintenance of MII arrest in porcine oocytes. [Greatwall kinase, Sus scrofa] (Mus musculus) PubMed

 12563.

Data indicate that LjEIN2-1 and LjEIN2-2 cooperatively regulate the nodule number: [LjEIN2-1 and LjEIN2-2] (Mus musculus) PubMed

 12564.

Data indicate that transient expression of the PpHAK2-green fluorescent protein (GFP) and PpHAK3-GFP fusion proteins in P. patens protoplasts localized to the endoplasmic reticulum and Golgi complex, respectively: [Pphak3] (Mus musculus) PubMed

 12565.

Data show tha PpCHX1-green fluorescent protein (GFP) fusion protein transiently expressed in P. patens protoplasts co-localized with a Golgi marker: [PpCHX1] (Mus musculus) PubMed

 12566.

Chronic infection by H pylori expressing CagA correlates with high circulating levels of BNP and IL-6 in patients with acute coronary artery disease. (Mus musculus) PubMed

 12567.

we compare the primary and secondary ligation spheres of the alternative oxidases with other di-iron carboxylate proteins and propose a mechanism for the reduction of oxygen to water. (Mus musculus) PubMed

 12568.

The majority of MepR mutations identified in these S. aureus clinical isolates are found in a linker region. [MepR] (Mus musculus) PubMed

 12569.

ToxR downregulates virulence factor production in response to cyclo(Phe-Pro). [ToxR] (Mus musculus) PubMed

 12570.

[yapsin] A C. glabrata mutant lacking all 11 yapsins, Cgyps1-11, possesses an enlarged vacuole and displays vma- (vacuolar membrane ATPase)-like phenotypes with elevated metal ion susceptibility in an alkaline pH medium. (Mus musculus) PubMed

 12571.

C. albicans contains an alternative endocytic pathway that is clathrin- and Arp2/3-independent. [Arp2, Arp3, clathrin] (Mus musculus) PubMed

 12572.

Authors propose a dual function of the Vps/VacJ ABC transporter system in both the maintenance of lipid asymmetry in the outer membrane and the intercellular spread of the bacteria between adjacent epithelial cells.[VpsC, VacJ] (Mus musculus) PubMed

 12573.

These data suggest that in Vibrio parahaemolyticus, RpoN plays an important role in carbon utilization regulation, which may significantly affect host colonization.[RpoN] (Mus musculus) PubMed

 12574.

The fbp1Delta mutant cannot disseminate to other organs following pulmonary infection in the murine inhalation model of cryptococcosis.[fbp1] (Mus musculus) PubMed

 12575.

These studies suggest that Toxoplasma gondii patatin-like protein 1 (TgPL1) plays a role in the maintenance of chronic Toxoplasma gondii infection.[PL1] (Mus musculus) PubMed

 12576.

(RAD-6) The absence of rad-6 activity leads to both ultraviolet hypersensitivity and a decline in metabolic rate and lifespan. (Mus musculus) PubMed

 12577.

mechanosensitive gating properties of MscCG [MscCG] (Mus musculus) PubMed

 12578.

the functional role of HIV-1 gp120 V3 loop and CXCR4 residues associated with HIV-1 coreceptor activity [gp120] (Mus musculus) PubMed

 12579.

Data show that yeast transformants expressing ZmAMT1;1a (GRMZM2G175140) and ZmAMT1;3 (GRMZM2G028736) led to a better growth complementation than that expressing ZmAMT1;1b (GRMZM2G118950): [ZmAMT1;1a] (Mus musculus) PubMed

 12580.

data indicate the HtrA is active under stress conditions which might support Hp colonizing in the gastric environment (Mus musculus) PubMed

 12581.

Inducible HSP70 chaperones SOD-2 to the mitochondria in the endothelial cells from developing lungs. [iHSP70] (Mus musculus) PubMed

 12582.

The C-terminal region, particularly the region containing the first 105aa, has an important role in OsHMA3 activity. [OsHMA3] (Mus musculus) PubMed

 12583.

The crystals of Scl2.3 diffracted to 1.5 A resolution and belonged to space group H32, with unit-cell parameters a = 44.23, b = 44.23, c = 227.83 A. [Scl2.3] (Mus musculus) PubMed

 12584.

the Corynebacterium glutamicum amylomaltase crystal diffracted to 1.7 A resolution and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 73.28, b = 82.61, c = 118.64 A.[amylomaltase] (Mus musculus) PubMed

 12585.

The result is that MgtR appears to be ideally situated in the membrane to influence the functionality of MgtC.[MgtR] (Mus musculus) PubMed

 12586.

Presented here are the expression, purification, crystallization and initial crystallographic analyses of cryptococcal adenylosuccinate synthetase. [adenylosuccinate synthetase] (Mus musculus) PubMed

 12587.

Tyr14 phosphorylation of P is essential for viral transcription and replication.[P protein] (Mus musculus) PubMed

 12588.

Bovine ephemeral fever rhabdovirus alpha1 protein binds bovin importin beta1 and importin 7. [alpha 1] (Mus musculus) PubMed

 12589.

This study confirms that the zorO-orzO pair is a true type I toxin-antitoxin locus (zorO, orzO). (Mus musculus) PubMed

 12590.

biochemical characterization and coenzyme sites evaluation of NADP(+)-specific isocitrate dehydrogenase [YLIDP] (Mus musculus) PubMed

 12591.

Cnb1 mutants had a distinct cell division phenotype and reduced virulence in seedling. [cnb1] (Mus musculus) PubMed

 12592.

The rice GERMINATION DEFECTIVE 1, encoding a B3 domain transcriptional repressor, regulates seed germination and seedling development by integrating gibberelic acid and carbohydrate metabolism.[GERMINATION DEFECTIVE 1] (Mus musculus) PubMed

 12593.

Alpha-glucosidase functions as a receptor of Cry11Ba [alpha-glucosidase] in Anopheles gambiae. (Mus musculus) PubMed

 12594.

Taken together, these results strongly suggest that cell population density signals inducing virulence gene expression can be overridden by nutrient availability, a condition monitored by CodY.[CodY] (Mus musculus) PubMed

 12595.

Authors conclude that, in Pukovnik, Xis-induced DNA bending is sufficient to promote intramolecular Int-mediated bridges during intasome formation.[Xis] (Mus musculus) PubMed

 12596.

aminolytic activity and halophilicity of (D)-stereoselective aminopeptidase [DamA] (Mus musculus) PubMed

 12597.

Authors demonstrated the presence of both 5'-to-3' exonucleolytic and endonucleolytic activities of RNase J on the Bacillus subtilis thrS transcript.[RNase J] (Mus musculus) PubMed

 12598.

DdPNGase play a role in development both during aggregation and in the differentiation of prespore cells (Mus musculus) PubMed

 12599.

Both AvrBs7 and AvrBs1.1 share a consensus protein tyrosine phosphatase (PTP) active site domain and can dephosphorylate para-nitrophenyl phosphate. [AvrBs1.1] (Mus musculus) PubMed

 12600.

demonstrated a direct interaction between BldG and the anti-sigma factor RsfA, which has been previously shown to regulate antibiotic production and morphological differentiation and to interact with the sporulation-specific sigma factor sigma(F) (RsfA) (Mus musculus) PubMed

 12601.

Homology modelling corroborates the very close similarity between hydra and human XPA.[XPA] (Mus musculus) PubMed

 12602.

the detailed morphological changes of the chicken PT primordium by detecting alphaGSU mRNA, was investigated.[alpha GSU] (Mus musculus) PubMed

 12603.

Orco, is localized to the flagella of A. gambiae spermatozoa where Orco-specific agonists, antagonists, and other odorant ligands robustly activate flagella beating in an Orco-dependent process. [Orco] (Mus musculus) PubMed

 12604.

In growing yeast there is a dynamic pool of inactive ribosomes that needs to be split by Dom34-Hbs1 and Rli1 to participate in protein synthesis. [strain BMA64; genes Dom34, Hbs1, and Rli1] (Mus musculus) PubMed

 12605.

Swi6p plays an important role in growth, deoxynivalenol production and virulence. [Swi6] (Mus musculus) PubMed

 12606.

VeA, VelB and FluG, are essential for conidiation, sclerotial production, and aflatoxin biosynthesis. [VeA, VelB and FluG] (Mus musculus) PubMed

 12607.

Authors show here that the histidine kinases DivJ together with CbrA and PleC participate in a complex phosphorylation system of the essential response regulator DivK in Sinorhizobium meliloti.[DivJ, CbrA, PleC, DivK] (Mus musculus) PubMed

 12608.

Authors show the involvement of four CRK1-associated cyclins, CYC2, CYC4, CYC5 and CYC7, in promoting the G1/S transition.[CYC2, CYC4, CYC5 and CYC7] (Mus musculus) PubMed

 12609.

roles for SCD in the regulation of lipid droplet size and membrane phospholipid composition [SCD] (Mus musculus) PubMed

 12610.

In the zebrafish swimmbladder infection model, dimorphic fungal growth, both localized and tissue-wide epithelial NF-kappaB activation, induction of NF-kappaB -dependent proinflammatory genes, and strong neutrophilia, are reported.[NF-kappab] (Mus musculus) PubMed

 12611.

The conserved Cys residues of Tim22 form an intramolecular disulfide bond.[Tim22] (Mus musculus) PubMed

 12612.

NdxA-dependent hydrolysis of nucleotides controls the catabolism of these carbon sources under O2-limited conditions [Nudix hydrolase] (Mus musculus) PubMed

 12613.

functional characteristics of Schizosaccharomyces pombe Vba2p [Vba2p] (Mus musculus) PubMed

 12614.

characterization of UDP-arabinopyranose mutase [UAM] (Mus musculus) PubMed

 12615.

This study provides insights into this coupling by resolving the first step in the transport cycle of the Suc transporter SUT1 from maize (Zea mays).[SUT1] (Mus musculus) PubMed

 12616.

The first crystal structures of two fungal GH62 alpha-L-arabinofuranosidases from the basidiomycete Ustilago maydis (UmAbf62A) and ascomycete Podospora anserina (PaAbf62A), are reported.[UmAbf62A] (Mus musculus) PubMed

 12617.

PDIA6 controls the decay of IRE1alpha signaling via disulfide-dependent association (Mus musculus) PubMed

 12618.

Study determines the crystal structure and probes the function of the chicken ASIC1a-MitTx complex, illuminating how the toxin binds to and stabilizes ASIC1a in a physiologically relevant, open-channel, sodium-selective state. (Mus musculus) PubMed

 12619.

In conclusion, authors report PSGL-1 as a novel target for pneumococcal ZmpC and show that ZmpC inhibits neutrophil extravasation during pneumococcal pneumonia.[ZmpC] (Mus musculus) PubMed

 12620.

HtpG physically interacts with DnaJ2 and DnaK2. DnaJ2, which belongs to the type II J-protein family, bound DnaK2 or HtpG with submicromolar affinity, and HtpG bound DnaK2 with micromolar affinity. (Mus musculus) PubMed

 12621.

These data have uncovered a function of endosomal sorting complex required for transport components in regulating PMR1 expression through the Nrg1/Rim101 pathway.[PMR1, nrg1, Rim101] (Mus musculus) PubMed

 12622.

a previously unknown structural role of the first five N-terminal residues of CYT-18 [CYT-18] (Mus musculus) PubMed

 12623.

Inactivation of purC, a gene encoding phosphoribosylaminoimidazole-succinocarboxamide synthase, caused complete loss of virulence in Xanthomonas campestris pv. campestris, the causal agent of black rot disease of cruciferous plants. [PurC] (Mus musculus) PubMed

 12624.

This analysis suggests that Efg1 has an ancient role as regulator of development in fungi, and is central to several regulatory networks.[Efg1] (Mus musculus) PubMed

 12625.

The EmrRsm-regulated EmrCABsm efflux pump is involved in the extrusion of hydrophobic compounds.[EmrCAB] (Mus musculus) PubMed

 12626.

The results of this study provide a clearer understanding of the allostery of GMP synthetase where, for the first time, key substrate binding and interdomain contacts are modeled and analyzed.[GMP synthetase] (Mus musculus) PubMed

 12627.

Data suggest that plasma membrane-localized glycoprotein CEBiP is a chitin elicitors (CE)-specific receptor: [CEBiP] (Mus musculus) PubMed

 12628.

Addition of Trichomonas vaginalis Fim1 to actin polymerization assays increases the speed of actin filament assembly and results in bundling of F-actin in a parallel and anti-parallel manner.[Fim1] (Mus musculus) PubMed

 12629.

Gene deletion and complementation assays confirmed that vpa1307, a ZnuA homolog, contributes to the growth of VP3218 under zinc depletion condition and that conserved histidine residues of Vpa1307 contribute to its activity.[ZnuA] (Mus musculus) PubMed

 12630.

Mutations in the chromodomain-like insertion severely compromise the ribosome stimulated ATPase of eEF3, strongly suggesting that it exerts an allosteric effect on the hydrolytic activity of eEF3.[YEF3] (Mus musculus) PubMed

 12631.

The altered sequence of IND1 did not affect IND1 mRNA stability, yet it led to a decrease in Ind1 protein level.[IND1] (Mus musculus) PubMed

 12632.

The global thermodynamic parameters from the initial state (backfolded Ly49 and m157) to the final state (Ly49*/(m157)2) are characterized by an unfavorable enthalpy that is compensated by a favorable entropy, making the interaction spontaneous.[m157] (Mus musculus) PubMed

 12633.

This work identifies intriguing mechanistic parallels between the eukaryotic QSOX enzymes and the DsbA/B system catalyzing disulfide bond generation in the bacterial periplasm. (Mus musculus) PubMed

 12634.

Mg3LysM is important for fungal evasion of pathogen-triggered immunity in wheat leaf tissue and that both CERK1 and CEBiP are required for activation of chitin-induced defenses, a feature conserved between rice and wheat. [CERK1 and CEBiP] (Mus musculus) PubMed

 12635.

A novel SC component, designated central region component1 (CRC1), in rice (Oryza sativa), was identified.[CRC1] (Mus musculus) PubMed

 12636.

G0S2 mRNAs are abundantly expressed in porcine liver and adipose tissues of greater omentum and suet fat, and sex affects porcine G0S2 tissue transcript levels; meanwhile, the genetic diversity of porcine G0S2 gene is abundant and 2 SNPs are a genetic factor affecting back fat thickness. [G0S2] (Mus musculus) PubMed

 12637.

Data indicate that the levels of phosphorylation of the phaseolin changed remarkably in the seed transition from dormancy to early germination stage: [phaseolin] (Mus musculus) PubMed

 12638.

The clostridial agr operon circuitry may be in place either to moderate the number of spores that are formed or simply as an energy-saving strategy. (Mus musculus) PubMed

 12639.

VvOMT3 is responsible for the final step in methoxypyrazine synthesis in grape berries and is the major determinant of 3-isobutyl-2-methoxypyrazine production. [VvOMT3] (Mus musculus) PubMed

 12640.

results suggest that NE1434 and CT610 participate in para-aminobenzoate biosynthesis [CT610] (Mus musculus) PubMed

 12641.

Suggest that Th cell peptides screened for secondary structures and MHC class II peptide-binding affinities can elicit T helper cytokine and proliferative responses to pneumococcal surface adhesin A (PsaA) peptides. (Mus musculus) PubMed

 12642.

KF992030 -KF992090 new channelrhodopsins (Mus musculus) PubMed

 12643.

co-operation required between both subunits of a [NiFe]-hydrogenase in controlling reactivity of the enzyme with H2 and O2.[[NiFe]-hydrogenase] (Mus musculus) PubMed

 12644.

We cloned a novel Tad1 gene and demonstrated that this gene is closely involved in copper bioaccumulation in Trichoderma reesei.[Tad1] (Mus musculus) PubMed

 12645.

Trehalose 6-phosphate phosphatase (TPS2 )plays pleiotropic roles in the control of growth and a number of related developmental processes in vitro and in planta that appear separate from trehalose synthesis.[TPS2] (Mus musculus) PubMed

 12646.

Enzymatic characterizations and activity regulations of N-acetyl-beta-D-glucosaminidase from the spermary of Nile tilapia [NAGase] (Mus musculus) PubMed

 12647.

these results reveal that coordination of ZNF219L with Sox9a is involved in the regulation of notochord-specific expression of sncgb.[ZNF219L] (Mus musculus) PubMed

 12648.

We describe the resistance of mutant dihydrofolate reductase proteins in P. vivax to the anti-malarial drug pyrimethamine. [DHFR] (Mus musculus) PubMed

 12649.

[Get5 protein] Hydrophobic residues from both small glutamine-rich tetratricopeptide-repeat protein (Sgt)2 and Get5 play an important role in cell survival under heat stress. (Mus musculus) PubMed

 12650.

Data indicate that interaction with Cu(2+) interrupted the biological activity of recombinant glycine-rich protein GRP162 by disrupting the secondary structure of the protein: [GRP162] (Mus musculus) PubMed

 12651.

MiR-23 inhibits porcine respiratory and reproductive syndrome virus replication by directly targeting viral RNA. [miR-23] (Mus musculus) PubMed

 12652.

MULTIPASS is a MYB transcription factor that is regulated by plant hormones and affects plant growth. [OsMPS] (Mus musculus) PubMed

 12653.

The fission yeast cell wall stress sensor-like proteins Mtl2 and Wsc1 act by turning on the GTPase Rho1p but act independently of the cell wall integrity pathway.[Mtl2] (Mus musculus) PubMed

 12654.

Results suggest that BmICE-2 (DQ360829) may be a pro-apoptotic gene with caspase-9 activity: [ICE-2 or BmICE-2] (Mus musculus) PubMed

 12655.

Data indicate that cntfa (encoding ciliary neurotrophic factor a; AB894420) and pdlim3a (encoding PDZ and LIM domain 3 a) genes were found to be located 3-4 Mb from and on opposite sides of the Y chromosome-specific region: [pdlim3a] (Mus musculus) PubMed

 12656.

The results suggested that the suppression of TaEIL1 transcripts could enhance the resistance of wheat to stripe rust fungus.[TaEIL1] (Mus musculus) PubMed

 12657.

The DWARF14 residues recognizing D-OH are critical for the strigolactone-dependent DWARF14-SLR1 interaction. [DWARF14], [SLR1] (Mus musculus) PubMed

 12658.

the transcription factor Promyelocytic Leukemia Zinc Finger (PLZF) plays a critical role shaping patterns of neuronal differentiation.[PLZF] (Mus musculus) PubMed

 12659.

The crystal structure of the UreG/UreF/UreH complex, which illustrates how UreF and UreH facilitate dimerization of UreG.[UreG, UreF, UreH] (Mus musculus) PubMed

 12660.

Mutations in the MAD-1 coiled coil that selectively disrupt interaction with BUB-1 eliminated MAD-1 localization to unattached kinetochores and between meiotic chromosomes, both of which require BUB-1, and abrogated checkpoint signaling. [Mad-1] (Mus musculus) PubMed

 12661.

the geranylation of (R)-benzodiazepinedione and five other cyclic dipeptides by AnaPT in the presence of geranyl diphosphate [AnaPT] (Mus musculus) PubMed

 12662.

rearrangements in the reaction catalyzed by the indole prenyltransferase FtmPT1 (Mus musculus) PubMed

 12663.

Overall, these results demonstrated that expression of sefA of SEF14 fimbriae enhances adhesion to epithelial cells, survival in macrophages and contributes to virulence in mice. (Mus musculus) PubMed

 12664.

These data suggest that gamma-glutamyltranspeptidase plays a significant role in the chronic inflammation caused by Helicobacter pylori infection.[gamma-glutamyltranspeptidase] (Mus musculus) PubMed

 12665.

our data indicate that Nod1 and Gef2 function cooperatively in a protein complex to regulate fission yeast cytokinesis. (Mus musculus) PubMed

 12666.

(frataxin) In frataxin-deleted strains expressing the bypass mutant Isu1, cell growth was restored to close to normal. (Mus musculus) PubMed

 12667.

(Cdc50) Twenty-two invariant residues in Cdc50 protein are identified, some of which are located in the extracellular domain. (Mus musculus) PubMed

 12668.

These results indicate that GLU1 contributes to the development and virulence of Pyrenophora tritici-repentis.[GLU1] (Mus musculus) PubMed

 12669.

Replacement of any cysteine residues reduced sulfur oxygenase reductase activity by 53-100%, while the mutants of H86A, H90A and E114A lost their enzyme activities largely.[sulfur oxygenase reductase] (Mus musculus) PubMed

 12670.

miR-150 and miR-200c play an important role in human endothelial lineage specification and chick embryonic vasculogenesis by targeting ZEB1.[miR200C, miR150] (Mus musculus) PubMed

 12671.

Present study extends our insights regarding the structure-function mechanism associated with the membrane pore formation by VCC, in the context of the beta-barrel pore-forming toxin mode of action. [VCC] (Mus musculus) PubMed

 12672.

A structure-guided model of the MepR-mepA operator complex suggests that MepR dimers do not interact directly and cooperative binding is likely achieved by DNA-mediated allosteric effects (MepR). (Mus musculus) PubMed

 12673.

this study demonstrates the interaction between type A and type B influenza nucleoproteins and suggests that the profound effect of BNP on limiting growth of FluA may occur by inhibiting proper formation of the FluA polymerase complex.[Nucleoprotein of influenza A virus ] (Mus musculus) PubMed

 12674.

These results provide insight into the evolutionary origin and functional context of Utp22 and Rrp7.[Utp22, Rrp7] (Mus musculus) PubMed

 12675.

Both OsYchF1 and OsGAP1 are localized mainly in the cytosol under sodium chloride treatment.[YchF1, GAP1] (Mus musculus) PubMed

 12676.

These data demonstrate the surprising result that functions encoded by the influenza A virus M segment impact neuraminidase activity and, perhaps through this mechanism, have a potent effect on transmissibility.[M, NA] (Mus musculus) PubMed

 12677.

Hd16 acts as an inhibitor in the rice flowering pathway by enhancing the photoperiod response as a result of the phosphorylation of Ghd7. [HD16; Ghd7] (Mus musculus) PubMed

 12678.

Ggt1 is responsible for the transfer of a galactose residue to a glycosphingolipid. [Ggt1] (Mus musculus) PubMed

 12679.

Rch1p does not functionally interact with the high-affinity Ca(2+) influx system. [Rch1p] (Mus musculus) PubMed

 12680.

Collectively, these results suggest the regulatory roles of small RNAs RyhB-1 and RyhB-2 in Salmonella on multiple cellular pathways, including motility, at a post-transcriptional level.[RyhB-1 and RyhB-2] (Mus musculus) PubMed

 12681.

The results confirmed that activities of mig-14 were important for cell invasion.[mig-14] (Mus musculus) PubMed

 12682.

Cells lacking HXK2 and showing a constitutive accumulation of activated Ras at the mitochondria are more sensitive to acetic-acid-induced programmed cell death compared to the wild type strain.[HXK2, ras] (Mus musculus) PubMed

 12683.

To obtain direct structural information on the fold of unlinked NS2B-NS3pro in solution, we tagged NS3pro with paramagnetic tags and measured pseudocontact shifts by NMR to position NS2Bc relative to NS3pro. (NS2B-NS3 protease) (Mus musculus) PubMed

 12684.

SadB is an inner membrane lipoprotein that is required for proper surface expression of SadA in S. enterica. [SadB] (Mus musculus) PubMed

 12685.

OsNUC1-S plays an important role in salt resistance during salt stress, a new role for nucleolin in plants. [OsNUC1-S] (Mus musculus) PubMed

 12686.

Tapgips and their homologues are involved in the wheat defence response by acting at the site of the lesion caused by pathogen infection. [Tapgip1; Tapgip2] (Mus musculus) PubMed

 12687.

The methyltransferase, helicase, and nonconserved region II (NONII) of p126 each has silencing-suppressor function. [p126] (Mus musculus) PubMed

 12688.

a conserved PCD-like protein, renamed alpha-carboxysome RuBisCO assembly factor (or acRAF), is a novel RuBisCO chaperone integral to alpha-carboxysome function [acRAF] (Mus musculus) PubMed

 12689.

The cellular hydrophobicity correlates with the FLO11D copy number, and the strain with a higher copy number of FLO11D exhibits a fitness advantage compared to a reference strain under osmostress static culture conditions (Mus musculus) PubMed

 12690.

The study was to assess the effect of the different aquatic conditions on anion transport of fish erythrocytes through the measurement of the sulphate uptake operating from band 3 protein. (Mus musculus) PubMed

 12691.

activation of the TGF-beta pathway after weaning induces the transcription of miR-424(322)/503, which in turn down-regulates the expression of key genes (Mus musculus) PubMed

 12692.

analysis of the glycoside hydrolase family 62 alpha-L-arabinofuranosidase from Streptomyces coelicolor [ScAraf62A] (Mus musculus) PubMed

 12693.

Amino acid changes in the PA protein of H7N9 influenza A viruses affects it virulence in mice. [PA] (Mus musculus) PubMed

 12694.

Recombinant Tri a 36 can be used for specific in vitro testing for IgE-associated wheat allergy in children [Tri a 36] (Mus musculus) PubMed

 12695.

Full-length MCPyV LT-Ag interacts with p53 and inhibits p53-dependent transcription. [LT] (Mus musculus) PubMed

 12696.

Single nucleotide polymorphisms within the mprF gene of Staphylococcus aureus are casually related to daptomycin resistance.[mprF],S. aureus Newman. (Mus musculus) PubMed

 12697.

The linkage of fusB and vapE may contribute to bacterial adaption/fusidic acid resistance.[FusB], [vapE] (Mus musculus) PubMed

 12698.

The crystallographic data GspB from Streptococcus gordonii can be fully explained by an alternative model, namely replacing the disaccharide with a buffer molecule.[GspB] (Mus musculus) PubMed

 12699.

Two glycine riboswitches activate the gcvT, gcvP and gcvH. [gcvP and gcvH] (Mus musculus) PubMed

 12700.

The exporter FexA exhibited two amino acid substitutions, Gly33Ala and Ala37Val, that confer only chloramphenicol, but not florfenicol, resistance. [FexA] (Mus musculus) PubMed

 12701.

Neither ERG11 overexpression nor variations in ERG11 coding sequences was responsible for the high azole resistance in the Pacific Northwest C. gattii strains. [Erg11]([CYP51]) (Mus musculus) PubMed

 12702.

These results show the PB2 E627K mutation has played an important role in this H7N9 influenza outbreak and in the pathogenicity of the H7N9 virus.[PB2] (Mus musculus) PubMed

 12703.

These results support the idea that the lipase activity of surface-exposed VolA likely contributes to the success of Vibrio cholerae, improving the overall adaptation and survival of the organism in different environments.[VolA] (Mus musculus) PubMed

 12704.

CK1 transmits the signal necessary to stall cytokinesis by phosphopriming Sid4 for Dma1-mediated ubiquitination. [CK1] (Mus musculus) PubMed

 12705.

A nonhyperbolic [MgATP]-velocity relationship when actin filaments are propelled by myosin subfragment 1 or full-length myosin, is described.[actomyosin] (Mus musculus) PubMed

 12706.

Activated and oligomeric SgrAI displays key protein-protein interactions near the helix axis between its N termini, as well as allosteric protein-DNA interactions that are required for enzymatic activation. (Mus musculus) PubMed

 12707.

The Nef-like effect of murine leukemia virus glycosylated gag on HIV-1 infectivity is mediated by its cytoplasmic domain and depends on the AP2M2. [APM2} (Mus musculus) PubMed

 12708.

Specific residues of PB2 and PA influenza virus polymerase subunits confer the ability for RNA polymerase II degradation and virus pathogenicity.[PB2, PA] (Mus musculus) PubMed

 12709.

Amino acid substitutions in PB2 gene contribute to the pathogenicity of the novel A/H7N9 virus.[PB2] (Mus musculus) PubMed

 12710.

Cloning, overexpression, and purification of the NS2B(H)-NS3pro complex, and a highly active recombinant NS2B(H)-NS3pro complex was obtained, useful for the design of high-throughput assays for flaviviral inhibitor. [NS2B] [NS3] (Mus musculus) PubMed

 12711.

The charged residues in PomA and in FliG collectively participate in torque generation of the Na+-driven flagellar motor.[PomA, FliG] (Mus musculus) PubMed

 12712.

CsEIN3 is involved in processes of flower development. [CsEIN3] (Mus musculus) PubMed

 12713.

This report demonstrates that under low oxidative stress conditions, a combination of membrane sensors, Mtl1 and either Wsc1 or Mid2, are required jointly to transmit the oxidative stress signal to initiate cyclin C destruction.[Mtl1, Wsc1, Mid2] (Mus musculus) PubMed

 12714.

In this study, authors have demonstrated that the ORF4b-encoded accessory protein (p4b) of MERS-CoV, may indeed facilitate innate immune evasion by inhibiting the type I IFN and NF-kappaB signalling pathways. (Mus musculus) PubMed

 12715.

evolutionary analysis of neuraminidase gene of A/H7N9 influenza virus [neuraminidase] (Mus musculus) PubMed

 12716.

Flucytosine antagonism of azole activity versus Candida glabrata is mediated by transcription factor Pdr1 and multidrug transporter Cdr1. [Pdr1],[Cdr1] (Mus musculus) PubMed

 12717.

[PID-1] PID-1 is a mostly cytoplasmic, germline-specific factor essential for 21U-RNA biogenesis, affecting an early step in the processing or transport of 21U precursor transcripts (Mus musculus) PubMed

 12718.

[PRDE-1] prde-1 (piRNA silencing-defective) as the first essential C. elegans piRNA biogenesis gene (Mus musculus) PubMed

 12719.

In vitro, abcA expression depends on rot and sarZ regulators in strain MW2.[abcA] (Mus musculus) PubMed

 12720.

In this study, authors identified in Streptococcus pyogenes a gene that exhibits a receptor-like function for peptide lantibiotic Smb and named that gene LsrS.[LsrS] (Mus musculus) PubMed

 12721.

NSvc2 glycoproteins was targeted to the golgi body by the N-terminal transmembrane domain and adjacent cytosolic 24 amino acids. [NSvc2] (Mus musculus) PubMed

 12722.

[MutS] The bending kinetics of MutS-mismatched DNA complexes may control the entry into functional pathways for downstream signaling of repair. (Mus musculus) PubMed

 12723.

the crystal structure of the Staphylococcus aureus sortase B enzyme in a covalent complex with an analog of its NPQTN sorting signal substrate [Sortase B] (Mus musculus) PubMed

 12724.

Structural basis and target-specific modulation of ADP sensing by the Synechococcus elongatus PII signaling protein [PII signaling protein] (Mus musculus) PubMed

 12725.

BdCAD1 and BdCOMT4 are two key genes in the lignin biosynthetic pathway that, when perturbed, may result in greater stem biomass yield and bioconversion efficiency. [BdCAD1; BdCOMT4] (Mus musculus) PubMed

 12726.

OsRRMh may confer one of its functions in the vegetative-to-reproductive transition in rice.[OsRRMh] (Mus musculus) PubMed

 12727.

study of localization of FtsZ, MreB and the 2 chemosensory clusters relative to each other during the cell cycle; found FtsZ moves from the new pole to the midcell after cell division and the membrane chemosensory clusters do not colocalize with FtsZ, but form large diffusing dynamic complexes [FtsaZ] (Mus musculus) PubMed

 12728.

This study provides a mechanism for the ability of the Helicobacter pylori Fur regulator to repress the expression of both iron-inducible and iron-repressible genes (Fur). (Mus musculus) PubMed

 12729.

Asf1A and Asf1B have strikingly different cellular localizations and functions (Asf1A and Asf1B). (Mus musculus) PubMed

 12730.

The deletion of BMT5 led to a dramatic reduction of PLM glycosylation and accumulation of PLM with a truncated beta-oligomannoside chain, respectively.(BMT5) (Mus musculus) PubMed

 12731.

(KCC2) A KCC2-dependent reversal potential of chloride ion difference exists between ON and OFF dendrites of larval retinal ganglion cells. (Mus musculus) PubMed

 12732.

These results suggest that RapGAP9 is involved in the regulation of cytoskeleton reorganization and cytokinesis. rapGAP9 null cells showed a small increase of cell-substratum attachment and slightly lower moving speed and directionality. (Mus musculus) PubMed

 12733.

The identification and cloning of Grain Size 6 (GS6), which plays an important role in reducing grain size in rice, is reported.[GS6] (Mus musculus) PubMed

 12734.

Chalk5 encodes a vacuolar H(+)-translocating pyrophosphatase influencing grain chalkiness in rice. [Chalk5] (Mus musculus) PubMed

 12735.

GtfA and GtfB are both required for protein O-glycosylation.[GtfA, GtfB] (Mus musculus) PubMed

 12736.

Injury to the omentum led to mobilization of TGF-beta3 and betaglycan-expressing cells from milky spots. [tgfbeta3] (Mus musculus) PubMed

 12737.

Investigation of the structural and sequence requirements of medaka telomerase RNA for telomerase catalytic activity (telomerase RNA) (Mus musculus) PubMed

 12738.

The flagellar soluble protein FliK determines the minimal length of the hook. [FliK] (Mus musculus) PubMed

 12739.

Mutations in the N-terminal region of COT1 is implicated in regulating hyphal elongation and branching, asexual conidiation and germination. (Mus musculus) PubMed

 12740.

study describes cell cycle mutant that reversibly arrests in G1 phase; the defect mapped to a gene encoding TgNoAP1; TgNoAP1 is tightly regulated and expressed in the nucleolus during G1/S phases; TgNoAP1 may be part of a dynamic mechanism that senses the health of the parasite protein machinery at the initial steps of ribosome biogenesis[NoAOP1] (Mus musculus) PubMed

 12741.

nsp10 helicase activity depends on the extensive relay of interactions between the zinc-binding domain and HEL1 domains (nsp10). (Mus musculus) PubMed

 12742.

multiple phosphorylation sites on maize endosperm starch branching enzyme IIb (Mus musculus) PubMed

 12743.

OsHsfB2b functions as a negative regulator in response to drought and salt stresses in rice.[OsHsfB2b] (Mus musculus) PubMed

 12744.

functional characterization of N-acetylglucosaminyltransferase I [GnTI] (Mus musculus) PubMed

 12745.

Higher copy number states existed in the diploid wild ancestors prior to the polyploidization events and that the loss of Cbf14 copies occurred in the cultivated germplasm.[Cbf14] (Mus musculus) PubMed

 12746.

Trans-generational absence of RNA Polymerase IV (Pol IV) conditions a fully colored kernel phenotype. [RNA Polymerase IV ] (Mus musculus) PubMed

 12747.

SPM1 recruits TrxL1 to the cortical microtubules. [TrxL1] (Mus musculus) PubMed

 12748.

Taken together, these results suggest that SACE_0012 is a negative regulator of Saccharopolyspora erythraea morphogenesis by mainly increasing the transcription of amfC gene.[SACE_0012 in strain A226] (Mus musculus) PubMed

 12749.

These findings indicate that 3'-phosphorylated RNA production from 2',3'-cyclic RNA by CvfA prevents RNA degradation by polynucleotide phosphorylase and contributes to the expression of agr and hemolysin genes. [CvfA, polynucleotide phosphorylase] (Mus musculus) PubMed

 12750.

OsMTP8.1 is an Manganese (Mn)-specific transporter that sequesters Mn into vacuoles in rice and is required for Mn tolerance in shoots.[MTP8.1] (Mus musculus) PubMed

 12751.

TaS3 is a potential susceptible gene and its function may be related to regulate SUMO functions.[Tas3] (Mus musculus) PubMed

 12752.

The differential expression of Aox2b1/2b2 suggests that a second gene has been originated by recent gene duplication with neofunctionalization.[Aox1, Aox2b] (Mus musculus) PubMed

 12753.

The expression of OsSUT1 in the grains of 'Genkitsukushi' was significantly higher than in 'Tsukushiroman' during the ripening period.[OsSUT1] (Mus musculus) PubMed

 12754.

Ectopic expression of MADS29 resulted in a severely dwarfed phenotype, exhibiting elevated levels of cytokinin, thereby suggesting that cytokinin biosynthesis pathway could be one of the major targets of OsMADS29.[OsMADS29] (Mus musculus) PubMed

 12755.

rpoN is an essential virulence gene of E. amylovora.[rpoN] (Mus musculus) PubMed

 12756.

These findings suggest the role of OsGRX8 in regulating abiotic stress response and may be used to engineer stress tolerance in crop plants.[OsGRX8] (Mus musculus) PubMed

 12757.

HookA is a novel linker important for dynein-early endosome interaction in vivo. [HookA] (Mus musculus) PubMed

 12758.

The OsLTP6 promoter achieved anther-specific expression through a combination of positive and negative regulatory elements.[OsLTP6] (Mus musculus) PubMed

 12759.

Presented are several crystal structures of Alg17c, a PL17 family alginate lyase, along with structure-function characterization of active site residues that are suggested to be involved in the exolytic mechanism of alginate depolymerization. [Algc] (Mus musculus) PubMed

 12760.

The Cys-rich region of OsDEP1 may function directly as a trap for Cadmium ions.[DEP1] (Mus musculus) PubMed

 12761.

[Tax protein] BLV could be divided into two categories on the basis of amino acid at position 233 of the Tax protein, which strongly correlated with leukemogenicity (Mus musculus) PubMed

 12762.

Peptidoglycan analysis of a Deltapgp1Deltapgp2 double mutant demonstrated that Pgp2 activity is required to generate the tripeptide substrate for Pgp1.[Pgp2, Pgp1] (Mus musculus) PubMed

 12763.

This1 provides joint control between shoot branching and reproductive development.[This1] (Mus musculus) PubMed

 12764.

self-interaction is crucial to the ability of the 2b protein to suppress silencing and induce a symptom-like phenotype.[2b protein] (Mus musculus) PubMed

 12765.

Study reports the crystal structure of Streptococcus pyogenes Cas9 in complex with sgRNA and its target DNA at 2.5 A resolution. The structure revealed a bilobed architecture composed of target recognition and nuclease lobes, accommodating the sgRNA:DNA heteroduplex in a positively charged groove at their interface.[Cas9] (Mus musculus) PubMed

 12766.

HSV-1 single stranded DNA binding protein (ICP8), and the helicase/primase complex (UL8/UL5/UL52) form a nuclear complex in transfected cells that is necessary and sufficient to disable ATR signaling. (Mus musculus) PubMed

 12767.

abcB and abcA contribute to drug resistance and virulence. [abcB, abcA] (Mus musculus) PubMed

 12768.

These results provide direct evidence that YGL2 has a vital function in rice Chl biosynthesis.[YGL2] (Mus musculus) PubMed

 12769.

BcRAS1 and BcRAC are involved in differentiation, virulence, and the cell cycle.[BcRAS1 and BcRAC] (Mus musculus) PubMed

 12770.

cross-resistance between PmB and LL-37 involved the Bap1 protein, whereby Bap1 on OMVs traps LL-37 with no subsequent degradation of the AMP. (Mus musculus) PubMed

 12771.

NMR structure of the chicken CD3epsilondelta/gamma heterodimer revealed a unique dimer interface that results in a heterodimer with considerable deviation from the human and murine CD3epsilondelta and CD3epsilongamma; chicken CD3epsilondelta/gamma heterodimer also contains a unique molecular surface, with the majority of surface-exposed, nonconserved residues being clustered to a single face of the heterodimer.[CD3g] (Mus musculus) PubMed

 12772.

both the UL138 and LUNA-specific CD4 T cell responses included CD4 T cells that secreted the immunosuppressive cytokine cIL-10. (Mus musculus) PubMed

 12773.

Nitric oxide is involved in the complex control of PEPCase-k activity, and it may mediate some of the plant responses to salinity. (Mus musculus) PubMed

 12774.

Both NS2 and NS3 are necessary for Aleutian mink disease virus replication. [NS2,NS3] (Mus musculus) PubMed

 12775.

VRN-A1 is required for vernalization in winter wheat. [TaVRN-A1] (Mus musculus) PubMed

 12776.

Mrh4 plays an essential role during the late stages of mitoribosome assembly by promoting remodeling of the 21S rRNA-protein interactions.[Mrh4] (Mus musculus) PubMed

 12777.

MERS-CoV 4a protein interacted with PACT in an RNA-dependent manner but not with RIG-I or MDA5.[4a] (Mus musculus) PubMed

 12778.

This work presents a new role for Snf1/AMP-activated protein kinase (AMPK) pathways in lipid accumulation in this oleaginous yeast.[Snf1] (Mus musculus) PubMed

 12779.

CiaD contributes to disease and contains a Mitogen-activated protein (MAP) kinase-docking site that is found within effector proteins produced by other enteric pathogens.[Campylobacter invasion antigens. [CiaD)] (Mus musculus) PubMed

 12780.

While both deubiquitinase domains showed de-ubiquitinating activity , highly pathogenic-PRRSV demonstrated a strong preference for lysine 63-linked poly-Ubiquitin, tied to innate immune response regulation.[NS2] (Mus musculus) PubMed

 12781.

OsGZF1 has a function in regulating the GluB-1 promoter and controls accumulation of glutelins during grain development. [OsGZF1; GluB-1] (Mus musculus) PubMed

 12782.

Mechanistic investigations of unsaturated glucuronyl hydrolase from Clostridium perfringens. (Mus musculus) PubMed

 12783.

OsYSL6 is a Mn-nicotianamine transporter that is required for the detoxification of excess Mn in rice. [OsYSL6] (Mus musculus) PubMed

 12784.

miR319 plays important roles in leaf morphogenesis and cold tolerance in rice.[miR319] (Mus musculus) PubMed

 12785.

MinCDE system is sufficient to cause spatial regulation of FtsZ, required for Z-ring positioning.[FtsZ, MinC, MinD, MinE] (Mus musculus) PubMed

 12786.

During iron starvation, SidJ deficiency resulted in decreased growth and increased intracellular accumulation of hydrolysis products of the siderophore fusarinine C.[SidJ] (Mus musculus) PubMed

 12787.

Disulfide cross-linking of transport and trimerization domains of a neuronal glutamate transporter restricts the role of the substrate to the gating of the anion conductance. (Mus musculus) PubMed

 12788.

Loss of cbrA results in a significantly decreased rate of DivK polar localization when compared with the wild-type, suggesting CbrA helps regulate cell cycle processes by modulating DivK phosphorylation status as a kinase.[CbrA] (Mus musculus) PubMed

 12789.

MS8 might be involved in maintenance of mitochondrial integrity [Ms8] (Mus musculus) PubMed

 12790.

The affinity between GID1 and DELLA proteins(Rht-B1c), is key to regulation of the stability of DELLA proteins and differential interactions determine dominant and semidominant gene responses to gibberellin. [Rht-B1c] (Mus musculus) PubMed

 12791.

The lethal phenotype of deletion of hemF or hemH could be remediated by heme supplementation confirming that Aspergillus niger is capable of hemin uptake.[hemF, hemH] (Mus musculus) PubMed

 12792.

Here, we investigated the effect of the tco mutation on nodulation using a grafting approach. The results strongly indicate that the nodulation-deficient phenotype of the mutant results from malfunction of the TCO gene in the root. [TRICOT] (Mus musculus) PubMed

 12793.

Direct regulation of LjPT4 by LjMAMI. The expression of both genes in non-mycorrhizal tissues leads to the hypothesis that these symbiosis-inducible genes are also involved in Pi starvation responses in root meristems... [LjMAMI] (Mus musculus) PubMed

 12794.

The study presents the X-ray crystal structure of the passenger domain of plasmid encoded toxin (Pet) at 2.3 A. [plasmid encoded toxin] (Mus musculus) PubMed

 12795.

Identified are cis elements responsible for SamDC expression by in silico analysis. Study provides qPCR analysis of SamDC expression to abiotic and biotic stress treatments. [SamDC] (Mus musculus) PubMed

 12796.

Results demonstrate that red light-induced suppression of photomorphogenesis, perceived in the shoot bottom, is a red high irradiance response of PhyA.[PhyA] (Mus musculus) PubMed

 12797.

The recombinant CsHPL was confirmed to have 9/13-HPL enzymatic activity. Gene expression levels of CsHPL were measured in different organs, especially in fruits of different development stages of both lines (Mus musculus) PubMed

 12798.

These studies establish the essentiality of ATP hydrolysis by LptB to power lipopolysaccharide transport in cells and suggest strategies to inhibit transporter function away from the LptB active site.[LptB] (Mus musculus) PubMed

 12799.

Crystal structures of N-terminal fragments containing the VWA and TSR1 domains for proMIC2 and MIC2 reveal a closed conformation of the VWA domain and how it associates with the TSR1 domain.[MIC2] (Mus musculus) PubMed

 12800.

The newly characterized mutations in Rht-B1 and Rht-D1 confer "gibberellin (GA)-insensitive" dwarfism by producing DELLA proteins that do not bind the GA receptor GA INSENSITIVE DWARF1, potentially compromising their targeted degradation.[RHT-1] (Mus musculus) PubMed

 12801.

Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 nuclear translocation. (Mus musculus) PubMed

 12802.

Entamoeba histolytica contains an occludin-like protein that can alter colonic epithelial barrier function. [Occludin] (Mus musculus) PubMed

 12803.

residues critical for pH-gating [OmpG] (Mus musculus) PubMed

 12804.

PpCMT is essential for Physcomitrella patens protonema and gametophore development and is involved in CHG methylation. [PpCMT] (Mus musculus) PubMed

 12805.

this found an uncharacterized keratin gene BLSK1 on chromosome 7 that was expressed specifically in barbule cells in regenerating chicken feathers. [BLSK1] (Mus musculus) PubMed

 12806.

OsSRO1c in mediating responses to multiple abiotic stresses. [OsSRO1c] (Mus musculus) PubMed

 12807.

These results indicate that the Ssp is associated with pathogenicity in Caenorhabditis elegans and one could speculate that the lipase activity itself is responsible for this virulence.[Ssp] (Mus musculus) PubMed

 12808.

The AAA+ ATPase D5 is the virus genome-uncoating factor. [AAA+ ATPase D5] (Mus musculus) PubMed

 12809.

Authors show that pVIn is associated with mature human adenovirus, where it binds at the base of peripentonal hexons in a pH-dependent manner.[pVI, hexon] (Mus musculus) PubMed

 12810.

This work provides a first insight into the mechanism of virulence acquisition through deletion of the highly polymorphic region in the haemagglutinin-esterase, with fusion enhancement acting as a major contributing factor. (Mus musculus) PubMed

 12811.

effect of the skeletal myopathy-causing E117K mutation in human beta-tropomyosin on actomyosin structure during the ATPase cycle [actomyosin] (Mus musculus) PubMed

 12812.

binding of L-homocysteine or methionine results in conformational rearrangements at the amino acid binding pocket, moving the catalytic zinc into position to activate the thiol group (Met6p, methionine synthase) (Mus musculus) PubMed

 12813.

Identification of five novel mutations in the ATPC gene associated with resistance to optochin (ATPC). (Mus musculus) PubMed

 12814.

we did not observe any association of 11-betaHSD1 4478T>G with parameters of obesity and insulin resistance. (Mus musculus) PubMed

 12815.

Rice OxO can be utilized effectively in plant genetic manipulation for sheath blight resistance.[Oxalate oxidase] (Mus musculus) PubMed

 12816.

(cytochrome oxidase 4) Chronic hypoxia reduced COX4 activity in fetal liver and lung. (Mus musculus) PubMed

 12817.

The dnl1 gene affects growth and the gibberellic acid metabolic pathway [dnl1] (Mus musculus) PubMed

 12818.

RT-PCR analysis demonstrated specific expression of the NPGL precursor mRNA in the hypothalamic infundibulum. Furthermore, the mRNA levels in the hypothalamic infundibulum increased during post-hatching development.(neurosecretory protein NPGL) (Mus musculus) PubMed

 12819.

The unsheathed flagellar filament of Shewanella oneidensis MR-1 is composed of two highly homologous flagellins, FlaA, and the major structural unit, FlaB.[FlaA, FlaB] (Mus musculus) PubMed

 12820.

The results suggested that HBZ suppressed cyclin D1 transcription through interactions with CREB.[HBZ] (Mus musculus) PubMed

 12821.

The combination of DNA with the HipB dimer is energetically favorable for the combination of HipB dimer with HipA protein.[HipA, HipB] (Mus musculus) PubMed

 12822.

We have characterized the dnf2 M. truncatula mutant blocked in the symbiotic process after bacterial infection of the symbiotic cells...which raises DNF2 as a starting point to investigate the molecular basis of symbiotic repression of plant defenses. (Mus musculus) PubMed

 12823.

MoIlv2 plays a crucial role in isoleucine and valine biosynthesis, whereas MoIlv6 contributes to isoleucine and leucine biosynthesis.[MoIlv2, MoIlv6] (Mus musculus) PubMed

 12824.

[nbs1] identified the C. cinereus nbs1 gene and demonstrated that it corresponds to a complementation group previously known as rad3 (Mus musculus) PubMed

 12825.

RanGap2 genetic variability does not influence the specificity of GPA2 recognition but is able to modulate this activity by enhancing the defence response.[GPA2] (Mus musculus) PubMed

 12826.

The serine protease/heat shock protein (HtrA) appears essential for the survival of Salmonella Enteritidis in egg white at chicken body temperature.[HtrA] (Mus musculus) PubMed

 12827.

[strain c83902] [flagellin] and [f4 fimbriae] Biofilm formation was reduced in the fliC mutant but increased in the faeG mutant, as compared with the wild-type strain (Mus musculus) PubMed

 12828.

[Apoc1] Apoc1b controls epiboly via E-cadherin-mediated radial intercalation in a gradient-dependent manner (Mus musculus) PubMed

 12829.

Lectin receptor-like kinase (LecRK) connects the common physiological pathway between germination and immunity in rice. (Mus musculus) PubMed

 12830.

Serine/threonine protein kinase (STN)8 gene is essential in photosystem II repair [STN8] (Mus musculus) PubMed

 12831.

both Cu,Zn superoxide dismutase genes are required to confer full virulence, sodC2 contributing slightly more than sodC1 to Salmonella pathogenesis[sodC1, sodC2] (Mus musculus) PubMed

 12832.

The XopX bacterial effector protein targets basic innate immunity in plants, resulting in enhanced plant disease susceptibility. (Mus musculus) PubMed

 12833.

the characterization of the Bs4 promoter and its application for low-level expression of bacterial type III effector proteins in planta [Bs4] (Mus musculus) PubMed

 12834.

We propose that the PrgK protein family functions as an essential molecular platform for Type III secretion systems assembly [PrgK] (Mus musculus) PubMed

 12835.

FloR functions as transporter specific for structurally associated phenicol drugs which utilizes the proton motive force to energize an active efflux mechanism; identified two residues essential for efflux action [FloR] (Mus musculus) PubMed

 12836.

data support a model of regulation whereby, in response to unknown signals, the PreB sensor activates PreA, which in turn indirectly upregulates pmrCAB transcription [PreA, PreB] (Mus musculus) PubMed

 12837.

SO13 and another Salmonella genomic island 1 gene(s) coordinately upregulate invasion in S. typhimurium DT104 exposed to rumen protozoa.[SO13] (Mus musculus) PubMed

 12838.

Here we report the identification of a Salmonella-specific translocated effector called SseL that is required for full virulence during murine typhoid-like disease. (Mus musculus) PubMed

 12839.

Our study describes the first T1SS-secreted protein that functions as a non-fimbrial adhesin in binding to eukaryotic cells. [SiiE] (Mus musculus) PubMed

 12840.

findings demonstrate a role for SopD in manipulation of host-cell membrane during S. typhimurium invasion and reveal the nature of its cooperative action with SopB.[SopD and SopB] (Mus musculus) PubMed

 12841.

Fur activates hilA transcription in a HilD-dependent manner.[Fur, HilA and HilD in strain ATCC 14028] (Mus musculus) PubMed

 12842.

We show that in Salmonella enterica serovar Typhimurium, deletion of the luxS gene polarizes flagellar phase variation toward the more immunogenic phase 1 flagellin. [LuxS in strain SL1344] (Mus musculus) PubMed

 12843.

In the present study, evidence is presented that a serovar Typhimurium SR-11 delta-frdABCD delta-sdhCDA double mutant is avirulent in BALB/c mice. [frdABCD and sdhCDA in strain SR-11] (Mus musculus) PubMed

 12844.

mutation studies revealed that the N-terminal 100-140 aa (especially amino acids 135-138) of SipB were required for its localization on the bacterial outer membrane.[SipB in strain SF530] (Mus musculus) PubMed

 12845.

Results show that the yliH in Salmonella more or less affects motility and adherence by enhancing these activities [yliH] (Mus musculus) PubMed

 12846.

These findings suggest that the putative transporter encoded by the yejABEF operon is involved in counteracting antimicrobial peptides, and that it contributes to the virulence of Salmonella.[yejA, yejB, yejE, yejF] (Mus musculus) PubMed

 12847.

TlpA is a novel prokaryotic modulator of NF-kappa B activity and IL-1 beta secretion that contributes to serovar enteritidis virulence [TlpA; TIR-like protein A] (Mus musculus) PubMed

 12848.

functional characterization of FimH adhesins of Salmonella Enteritidis & Salmonella Typhimurium showed close similarities between these proteins; Salmonella Enteritidis FimH bound with highest K(d) to high-mannose type N-glycans carried by RNase B [FimH] (Mus musculus) PubMed

 12849.

The objectives of this study were to enumerate S. enteritidis colonization in fecal, cecal, and internal organs, and to compare the level of expression of hilA of experimentally challenged laying hens fed different diets.[hilA] (Mus musculus) PubMed

 12850.

kinetic and x-ray crystallographic analysis of alpha-D-Glucose-1-phosphate cytidylyltransferase [alpha-D-Glucose-1-phosphate cytidylyltransferase] (Mus musculus) PubMed

 12851.

Salmonella RpoS, because it reacts to the presence of NO or its reactive derivatives, is thought to have a role in the pathogenicity of serovar Typhi [RpoS] (Mus musculus) PubMed

 12852.

We propose that IgeR may co-ordinate gene expression during Salmonella's transition from an extracellular to an intracellular environment. [IgeR] (Mus musculus) PubMed

 12853.

PltA and PltB associate with CdtB to form a multipartite toxin, and are required for the delivery of CdtB from an intracellular compartment to target cells via autocrine and paracrine pathways.[CdtB, PltA, PltB] (Mus musculus) PubMed

 12854.

evidence presented that AGS3 along with AGS1 and AGS2 is responsible for cell wall alpha(1-3)glucan biosynthesis and can modulate virulence of A. fumigatus [AGS3] (Mus musculus) PubMed

 12855.

ECM33 is a GPI-anchored protein with role in condial cell wall biosysnthesis; mutation of the gene results in conidia that were more resistant to killing by phagocytes, whereas the mycelium was more easily killed by neutrophils [Ecm33] (Mus musculus) PubMed

 12856.

A F389L substitution in squalene epoxidase (ErgA) conferred terbinafine resistance to this pathogenic mold [ErgA] (Mus musculus) PubMed

 12857.

GliZ, a putative Zn(2)Cys(6) binuclear transcription factor, regulates gliotoxin biosynthesis and contributes to Aspergillus fumigatus virulence (GliZ). (Mus musculus) PubMed

 12858.

analysis of mpkA deletion mutants revealed severe sensitivity of the mutants against cell wall active compounds, drastical alterations of the fungal morphology and increased resistance against oxidative stress.[mpkA] (Mus musculus) PubMed

 12859.

These experiments implicate PpoC (dioxygenase)in the regulation of A. fumigatus fungal development and host cell interactions. (Mus musculus) PubMed

 12860.

These results support that 2B insertion and pore-opening are mechanistically distinguishable events modulated by the target membrane anionic phospholipids.[2B protein] (Mus musculus) PubMed

 12861.

These results are consistent with a specific proteolysis of Nup98 by 2A protease to prevent de novo mRNA traffic in poliovirus-infected cells.[2A protease] (Mus musculus) PubMed

 12862.

Viral proteins 2C, 2BC, 3D, and 3CD were detected in all three immunopurified 3A samples.[3A] (Mus musculus) PubMed

 12863.

Our data are consistent with the idea that AvrBs3 manipulates expression of plant genes involved in the establishment of compatible and incompatible interactions. [AvrBs3] (Mus musculus) PubMed

 12864.

Structure-based sequence analysis and phylogenic tree construction reveal determinants of substrate specificity and divergence of families (2-isocitrate lyase) (Mus musculus) PubMed

 12865.

the surface of the signal-transducing protein EIIA(Glc) interacts with the MalK subunits of the maltose ATP-binding cassette transporter (MalFGK2) of Salmonella typhimurium [signal-transducing protein EIIA(Glc)] (Mus musculus) PubMed

 12866.

we have determined that the sirA gene is activated by crp and cya.[sirA] (Mus musculus) PubMed

 12867.

The results indicate the critical role of the NsrR-regulated Hmp in protection of Salmonella from nitrosative stress within and outside macrophages.[NsrR, Hmp] (Mus musculus) PubMed

 12868.

expression of Salmonella RstA was able to downregulate the expression of three RpoS-controlled genes (narZ, spvA, and bapA). This downregulation was achieved by a reduction in RpoS cellular levels.[RstA. RpoS] (Mus musculus) PubMed

 12869.

invR encodes a small non-coding RNA (sRNA) that represses the synthesis of the abundant OmpD porin. [invR in strain SL1344] (Mus musculus) PubMed

 12870.

flagellar proteins of Salmonella enterica serovar Typhimurium are exported even in the absence of FliI (Mus musculus) PubMed

 12871.

The S. Typhimurium smpA mutant was attenuated in mice by both the oral and parenteral routes of infection, and SmpA appeared to be most important for the growth of S. Typhimurium at systemic sites.[SmpA in strain SL1344] (Mus musculus) PubMed

 12872.

The open reading frame of the dps gene, together with all the upstream regulatory elements, were cloned;this work shall aid further investigations into the mechanism of Dps glycosylation.(Dps) (Mus musculus) PubMed

 12873.

A comprehensive biophysical analysis of the dynamic conformational behavior of the truncated monomeric needle subunit proteins MxiH(Delta5), BsaL(Delta5), and PrgI(Delta5), is presented.[PrgI] (Mus musculus) PubMed

 12874.

SopB mediates PI(3)P production on the SCV indirectly through recruitment of Rab5 and its effector Vps34.[SopB] (Mus musculus) PubMed

 12875.

binding to SKIP requires SifA residues W197 and E201 of the conserved WxxxE signature sequence, leading to the speculation that bacterial G protein mimicry may result in G protein antagonism [SifA] (Mus musculus) PubMed

 12876.

transcriptional cross-talk between SPI-1 and SPI-2, where the SPI-1-encoded regulator HilD is essential for the activation of both the SPI-1 and SPI-2 regulons but at different times during the stationary phase [SPI-1, SPI-2, HilD] (Mus musculus) PubMed

 12877.

SpiC is involved in the expression of FliC, which plays a significant role in the SPI-2-dependent activation of MAPK pathways in Salmonella infection.[SpiC, FliC] (Mus musculus) PubMed

 12878.

Over expression of Rma plays a role in mdr efflux pump mediated fluoroquinolone resistance in Salmonella. [Rma] (Mus musculus) PubMed

 12879.

Study analyzed the crystal structure and enzyme stability of SurE from Salmonella enterica Typhimurum strain IFO12529: [SurE] (Mus musculus) PubMed

 12880.

Mutants of hfq and smpB directly or indirectly modulate at least 20% and 4% of all possible Salmonella proteins, respectively, with limited correlation between transcription and protein expression. [Hfq;SmpB] (Mus musculus) PubMed

 12881.

we report the X-ray structure of the Salmonella typhimurium glucose/galactose receptor protein bound to the physiologically relevant ligand, (2R)-glyceryl-beta-D-galactopyranoside, solved by molecular replacement, and refined to 1.87 A resolution (Mus musculus) PubMed

 12882.

Monovalent cations and alpha-site ligands act synergistically to modulate the switching of the beta-subunit from the open to the closed conformation, which is crucial to the regulation of beta-site catalytic activity. (tryptophan synthase subunit beta) (Mus musculus) PubMed

 12883.

Atomic-level unfolding pathways and the mechanical efforts involved in stretching and unzipping were obtained for the four-domain flagellin from S. typhimurium.[Flagellin] (Mus musculus) PubMed

 12884.

deletion of polyphosphate kinase (PPK) resulted in augmented expression of cAMP receptor protein (CRP) and rpoS and lowered H2O2 sensitivity. [polyphosphate kinase (PPK)/ cAMP receptor protein (CRP)/rpoS/S. Typhimurium ATCC14028] (Mus musculus) PubMed

 12885.

The importance of the Salmonella effector protein AvrA in intestinal inflammation, bacterial translocation, and chronic infection in vivo, was demonstrated.[AvrA] (Mus musculus) PubMed

 12886.

SifA may use a similar mode of action via Rho proteins to alter yeast peroxisomal and mammalian endosomal membranes.[SifA] (Mus musculus) PubMed

 12887.

OASS-B dynamic and functional properties [OASS-B] (Mus musculus) PubMed

 12888.

MicA is involved in biofilm formation. [MicA] (Mus musculus) PubMed

 12889.

The capacity of Hfq to occupy and sequester the RNA 3' end has important implications for the mechanisms by which Hfq is thought to affect small RNA stability, turnover, and regulation.[Hfq] (Mus musculus) PubMed

 12890.

These results suggest that SseL alters host lipid metabolism in infected epithelial cells by modifying the ubiquitination patterns of cellular targets.[SseL] (Mus musculus) PubMed

 12891.

The MgtR peptide did not affect transcription of the mgtA gene but specifically bound to the MgtA transporter in vivo, resembling the features of MgtR-regulated MgtC expression.[MgtR] (Mus musculus) PubMed

 12892.

Flagellar Regulator fliT Represses Salmonella Pathogenicity Island 1 through flhDC and fliZ [FliT, strain 14028] (Mus musculus) PubMed

 12893.

Impaired protein import was observed in chloroplasts in which Hsp70-2 function was conditionally diminished. [Hsp70-2] (Mus musculus) PubMed

 12894.

Deletion of Pp POT1 results in catastrophic loss of bulk telomeric DNA, increased G-overhangs, and end-to-end chromosome fusions. [POT1] (Mus musculus) PubMed

 12895.

Study indicates that AgfC and AgfE are important for AgfA extracellular assembly, facilitating the synthesis of Salmonella thin aggregative fimbriae. [AgfC, AgfE protein]. (Mus musculus) PubMed

 12896.

AroA and aroD mutants are not able to form biofilms. [aroA. aroD ] (Mus musculus) PubMed

 12897.

Taken together, these data demonstrated that the Tat B and TatC proteins play a role in Salmonella Enteritidis pathogenesis.[Tat B and TatC] (Mus musculus) PubMed

 12898.

The authors demonstrate for the first time that antibodies against the SPI-1 needle tip protein (SipD) inhibit Salmonella Enteritidis invasion.[SipD] (Mus musculus) PubMed

 12899.

The Se72 retron does not branch the template RNA by a 2'-5' phosphodiester bond and, instead, it uses a free 3'OH end of RNA for initiating the synthesis of sdsDNA. (Se72) (Mus musculus) PubMed

 12900.

The DeltaaceE mutant was less able to invade epithelial cells, less resistant to reactive oxygen intermediate, less able to survive within a chicken macrophage cell line and had a retarded growth rate compared with the parental strain.[aceE] (Mus musculus) PubMed

 12901.

Molecular structure of this enzyme (alpha-D-glucose-1-phosphate cytidylyltransferase) in this critter. (Mus musculus) PubMed

 12902.

these and other results suggest that the S. Typhi Tsx porin and ImpX inner membrane protein facilitate competing mechanisms of thymidine influx and efflux, respectively, to maintain the steady-state levels of internal nucleoside pools [tsx, impX] (Mus musculus) PubMed

 12903.

Study demonstrated that the stg fimbrial operon contributed to increased adherence to human epithelial cells. [stg protein] (Mus musculus) PubMed

 12904.

HlyE hemolysin is a new virulence determinant.[HlyE] (Mus musculus) PubMed

 12905.

A C354G mutation in S. Typhi EnvZ resulted in a substantial increase in autophosphorylation, while mutation of its other cysteine residue at position 277 to L or S decreased the EnvZ autophosphorylation level. (Mus musculus) PubMed

 12906.

These results demonstrated that thefljA-like gene on a linear plasmid of S. enterica serovar Typhi is a fljA gene, the repressor of fliC gene, and the inhibition by FljA is likely at the post-transcriptional level.[FljA] (Mus musculus) PubMed

 12907.

cry1 may have a function during UV exposure but is not essential for completing the developmental life cycle under laboratory conditions.[Cry1] (Mus musculus) PubMed

 12908.

Disruption of calcium signalling affected SsCutA and SsPg1 expression and decreased S. sclerotiorum virulence, whereas elevated cAMP levels reduced virulence without affecting gene expression. {CutA; Pg1] (Mus musculus) PubMed

 12909.

In phylogenetic analysis of the isolates and other published sequences, attenuated and tissue-adapted isolates clustered as genotypes significantly different from the field isolates that had not been passaged in chicken/duck embryos [VP1 ] (Mus musculus) PubMed

 12910.

CasA and CasB have functions that support growth under conditions of endoplasmic reticulum stress.[CasA, CasB] (Mus musculus) PubMed

 12911.

The enzyme was found to catalyse the prenylation of Trp at the C-7 position of the indole moiety, in the presence of dimethylallyl diphosphate (DMAPP); therefore, it functions as a 7-dimethylallyltryptophan synthase (7-DMATS).[Afu3g12930 homolog] (Mus musculus) PubMed

 12912.

Demonstrate improved transfection efficiency of chitosan/DNA complex by co-transfecting chitosanase gene. (Mus musculus) PubMed

 12913.

Data characterize an Aspergillus fumigatus CRZ1 homologue, CrzA and demonstrate its mediation of cellular tolerance to increased concentrations of calcium and manganese: [CrzA] (Mus musculus) PubMed

 12914.

enzymatic products of CdpNPT are derivatives of tryptophan-containing cyclic dipeptides with 3-DMA moieties, known as reverse prenyl residues, attached to N-1 of the indole rings; therefore, CdpNPT functions as a reverse N-prenyltransferase [CdpNPT] (Mus musculus) PubMed

 12915.

With an exception of 7-methyltryptophan, 23 substances were accepted by 7-DMATS and converted to their prenylated derivatives, indicating a more flexible substrate specificity of 7-DMATS compared to that of FgaPT2. [7-DMATS] (Mus musculus) PubMed

 12916.

An elastase inhibitor from Aspergillus fumigatus (AFUEI) was isolated, and its biochemical properties and primary structure examined.[AFUEI] (Mus musculus) PubMed

 12917.

msdS is involved in polarity and septation in A. fumigatus. [MsdS] (Mus musculus) PubMed

 12918.

RasA plays a crucial role in hyphal growth, asexual development and cell wall integrity.[RasA] (Mus musculus) PubMed

 12919.

Mnt1 is required for cell wall stability and full virulence. [Mnt1] (Mus musculus) PubMed

 12920.

The Aspergillus fumigatus homologue ncsA Neuronal Calcium Sensor, is characterized.[NcsA] (Mus musculus) PubMed

 12921.

Transcriptional profiling revealed 87 genes that are affected by loss of sterol-regulatory element binding protein (SrbA) function, and implicate SrbA in maintaining sterol biosynthesis and hyphal morphology [SrbA] (Mus musculus) PubMed

 12922.

Afcwh41 was involved in cell wall integrity, polarity, septation, and conidiation, probably by affecting the function of proteins required for cell wall synthesis. [cwh41] (Mus musculus) PubMed

 12923.

PKAR plays roles in the nuclear duplication cycle. [PkaR] (Mus musculus) PubMed

 12924.

Glycosylphosphatidylinositol anchoring determines the distribution of the AfPhoA in the cell membrane. [PhoA] (Mus musculus) PubMed

 12925.

Afams1 gene is required for morphogenesis and cellular function in A. fumigatus.(Afams1) (Mus musculus) PubMed

 12926.

In this study, the pmi1 gene was identified to encode phosphomannose isomerase in the human fungal pathogen Aspergillus fumigatus.[pmi1] (Mus musculus) PubMed

 12927.

determined three crystal structures in apo and ADP forms from Saccharomyces cerevisae (ScGet3-apo) and Aspergillus fumigatus (AfGet3-apo and AfGet3-ADP). [Get3] (Mus musculus) PubMed

 12928.

FtmOx1 is the first endoperoxide-forming non-heme Fe(ii) and alpha-ketoglutarate-dependent dioxygenase reported so far. [FtmOx1] (Mus musculus) PubMed

 12929.

identified MitA as the only MIPC transferase in A. fumigatus. The DeltamitA mutant lacks MIPC and MIPC-derived glycosphingolipids [mitA] (Mus musculus) PubMed

 12930.

TmpL is necessary for regulation of intracellular ROS levels and tolerance to external ROS, and is required for infection of mammals by the human pathogen Aspergillus fumigatus [TmpL] (Mus musculus) PubMed

 12931.

The transcriptional regulator ZafA upregulates the expression of zrfC and aspf2 under zinc-limiting conditions regardless of the ambient pH, whereas PacC represses the expression of these genes under acidic growth conditions.(zrfC and aspf2) (Mus musculus) PubMed

 12932.

The Afpmt2 gene was required for growth and played a role distinct from that of the Afpmt1 in Aspergillus fumigatus. (Mus musculus) PubMed

 12933.

role for PmrA in cation homeostasis and cell wall integrity [pmrA] (Mus musculus) PubMed

 12934.

Sensitivity of the GprC and GprD deletion mutant strains toward environmental stress caused by reactive oxygen intermediates was increased and the mutants displayed an attenuation of virulence in a murine infection model.[ GprC and GprD] (Mus musculus) PubMed

 12935.

These data demonstrate that the product of Aspergillus fumigatus easA is required for incorporation of chanoclavine-I-aldehyde into more-complex ergot alkaloids.[easA] (Mus musculus) PubMed

 12936.

The mutant lacking AfMkk2 shows an enhanced sensitivity to posaconazole and voriconazole and in agreement with its sensitivity to moderate temperatures, it is less virulent in a murine infection model.[AfMkk2] (Mus musculus) PubMed

 12937.

Both seem to be glucokinase and hexokinase required for balancing carbon flux in A. fumigatus and are indispensable for growth under all nutritional conditions.[Glucokinase, Hexokinase] (Mus musculus) PubMed

 12938.

Secretome analysis and protease inhibitor studies identified the secreted alkaline protease Alp1 as the central molecule responsible for the cleavage of human complement proteins C3, C4, and C5. (Mus musculus) PubMed

 12939.

Festuclavine formation was only observed when chanoclavine-I aldehyde was incubated with FgaOx3 and FgaFS simultaneously or as a tandem-reaction with a sequence of FgaOx3 before FgaFS.[FgaFS][FgaOx3] (Mus musculus) PubMed

 12940.

The role of the GEL4 gene was investigated in this study.[Gel4] (Mus musculus) PubMed

 12941.

Among the four orthologues, only OCH1 complemented the aggregation phenotype, the growth inhibition, the hypersensitivity to hygromycin and the protein glycosylation defects observed in Saccharomyces cerevisiae Scoch1 deletion mutant.[OCH1] (Mus musculus) PubMed

 12942.

active site lies toward the bottom of a negatively charged pocket and its layout has much in common with other solved members of the GH25 and related GH families[GH25] (Mus musculus) PubMed

 12943.

The Lys174Ala mutant is found to produce a hexahydropyrroloindole alkaloid that is "reverse-prenylated" at C-3 as its major product. [dimethylallyltryptophan synthase] (Mus musculus) PubMed

 12944.

MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation. [MpkA] (Mus musculus) PubMed

 12945.

involved in RNA replication process in endoplasmic reticulum-derived intracellular membranes [nsP1a/4 protein] (Mus musculus) PubMed

 12946.

These data indicate that the processing of VP90 and the release of human astrovirus from the cell are two caspases-related, but apparently independent, events. (Mus musculus) PubMed

 12947.

results suggest that SPI2 promotes intramacrophage survival by protecting Salmonella DNA from exposure to macrophage oxidants [Spi2] (Mus musculus) PubMed

 12948.

The immunodominant trimeric beta-barrel outer membrane protein OmpC from Salmonella typhi, the causative agent of typhoid, has been functionally characterized here (Mus musculus) PubMed

 12949.

In this work, we reveal the presence of a PhoP-activated operon within SPI-1. This operon is composed of the orgB and orgC genes, which encode a protein that interacts with the InvC ATPase and a putative effector protein of the TTSS. [PhoP, OrgB, OrgC] (Mus musculus) PubMed

 12950.

in diol dehydrase, binding of the coenzyme to the protein weakens the bond prior to binding of the substrate[diol dehydrase] (Mus musculus) PubMed

 12951.

Study concludes that Salmonella pathogenicity island 2-dependent F-actin meshwork formation depends on the kinase activity of SteC, which resembles more closely eukaryotic than prokaryotic kinases.[SteC] (Mus musculus) PubMed

 12952.

BaeSR system increases multidrug and metal resistance in Salmonella by inducing the AcrD and MdtABC drug efflux systems.[BaeS and BaeR] (Mus musculus) PubMed

 12953.

Dwonregulates expression of MgtC virulence factor and assists in its degradation. (MgtR) (Mus musculus) PubMed

 12954.

conformational changes of the nucleotide-binding subunits, MalK(2), of the maltose ATP-binding cassette importer MalFGK(2) during the transport cycle [MalFGK(2)] (Mus musculus) PubMed

 12955.

Helical arrays of membrane reconstituted MsbA are sensitive to subtle conformational changes induced by various transition state inhibitors. (MsbA) (Mus musculus) PubMed

 12956.

The structure of the active site of ribonucleotide reductase A chain (PDB 1R2F) in the radical state (tyrosyl radical) was studied using EPR. [ribonucleotide reductase A chain (PDB 1R2F)] (Mus musculus) PubMed

 12957.

Lipid A deacylase PagL, which detoxifies endotoxin, is latent in Salmonella enterica. This study determined the biological significance of this latency.[PagL] (Mus musculus) PubMed

 12958.

The significance of these results is that they provide the first systematic study of the effect of regulatory cross talk on the expression dynamics of flagellar, SPI1, and type 1 fimbrial genes.[SPI1] (Mus musculus) PubMed

 12959.

Expression of the micA gene is driven by a single sigma(E)-dependent promoter, micAp. [MicA] (Mus musculus) PubMed

 12960.

A total of 600-ns comparative molecular dynamics simulations of the chemotaxis aspartate receptor Tar in explicit lipid bilayers, were carried out.[Tar] (Mus musculus) PubMed

 12961.

The two consecutive glutamates in the beta4/alpha4 loop of T. maritima CheB that is absent in T. maritima CheY and in E. coli/S. typhimurium CheB may be one factor contributing to the low CheA affinity.[CheA, CheB] (Mus musculus) PubMed

 12962.

BapA contributes both to biofilm formation and invasion through the regular Salmonella infection route. [BapA] (Mus musculus) PubMed

 12963.

Our data support a role for PegA in the colonisation of poultry by S. Enteritidis. [PegA] (Mus musculus) PubMed

 12964.

This work indicates that wzz is a new target regulated by Dam methylation via adenine-specific DNA methylase (Dam) and demonstrates that DNA methylation not only affects the production of surface proteins but also of surface polysaccharides.[wzz; Dam] (Mus musculus) PubMed

 12965.

Using two mutants of low-adhesive FimH protein from S. Enteritidis (Gly61Ala and Phe118Ser), surface plasmon resonance analysis pointed to Ser118 as the major determinant of the high-adhesive phenotype of type 1 fimbriae from S. Enteritidis.[FimH] (Mus musculus) PubMed

 12966.

Tsx porin plays critical roles in membrane assembly and integrity and thus in the virulence of serovar Typhi.(tsx) (Mus musculus) PubMed

 12967.

It is concluded that phoP genes appear to play a more important role than rpoS genes in both cellular invasion and virulence of S. typhi, but not in immunogenicity in mice.[phoP,rpoS] (Mus musculus) PubMed

 12968.

Some S. Typhi isolates exhibit over-expression of Vi polysaccharide, which masks clinical detection of LPS O-antigen. The status of the rpoS gene is responsible for this phenomenon. [RpoS] [REVIEW] (Mus musculus) PubMed

 12969.

hlyE and taiA genes found in the SPI-18 pathogenicity island present RpoS-dependent induction at low pH or high osmolarity (hylE and taiA). (Mus musculus) PubMed

 12970.

Altogether, OmpR might regulate the YehUT system in Salmonella typhi under hypotonic growth condition.[OmpR, YehU, YehT] (Mus musculus) PubMed

 12971.

-dimethylallylated indole derivatives can be produced by chemoenzymatic synthesis with 4-dimethylallyltryptophan synthase[ 4-dimethylallyltryptophan synthase ] (Mus musculus) PubMed

 12972.

the methylcitrate synthase mutant displayed attenuated virulence and, furthermore, was cleared from tissues when mice survived the first phase of acute infection.[mcsA gene in strain CBS 144.89] (Mus musculus) PubMed

 12973.

These studies provide evidence that AFUA_5G09330 is a monomeric, cytoplasmic protein. (Mus musculus) PubMed

 12974.

the single UDP-galactofuranose transporter GlfB is required for galactofuranosylation in Aspergillus fumigatus [GlfB] (Mus musculus) PubMed

 12975.

The enzyme encoded by ENG2 (AFUA_2g14360) belongs to the glycoside hydrolase family 16 (GH16).[ENG2] (Mus musculus) PubMed

 12976.

These results indicate that transcription factor DvrA influences A. fumigatus virulence as well as its capacity to damage host cells and stimulate a proinflammatory response. [DvrA] (Mus musculus) PubMed

 12977.

The mating-induced heme peroxidase (HPX) 15 is an important factor in long-term fertility, and demonstrate that its function is required during multiple gonotrophic cycles.[HPX15] (Mus musculus) PubMed

 12978.

Authors propose that partitioning of the 2b protein between the cytoplasmic and nuclear/nucleolar compartments allows the virus to regulate the balance between virus accumulation and damage to the host.[2b] (Mus musculus) PubMed

 12979.

The results support a working model of LacY in which substrate binding induces alternating conformational states and provides insight into their specific kinetic, energetic, and mechanical properties.[LacY] (Mus musculus) PubMed

 12980.

Coimmunoprecipitation showed that VP08R interacts with both VP23R and nidogen-1, indicating that VP08R is a component of virus-mock basement membrane and is present on the cell membrane by binding to VP23R. (Mus musculus) PubMed

 12981.

The unusual attributes of SOD5-like fungal proteins, including the absence of zinc and an open active site that readily captures extracellular copper, make these superoxide dismutases well suited to meet challenges in zinc and copper availability.[SOD5] (Mus musculus) PubMed

 12982.

Up-regulation of expression of ATP citrate lyase by sucrose is a key event for inducing the trichothecene biosynthesis. (Mus musculus) PubMed

 12983.

Tpz1 SUMOylation prevents telomerase accumulation at telomeres by promoting recruitment of Stn1-Ten1 to telomeres.[Tpz1, Stn1] (Mus musculus) PubMed

 12984.

Loss of MoAtg24, a sorting nexin related to yeast Snx4, disrupts mitophagy and consequently leads to highly reduced conidiation.[Atg24] (Mus musculus) PubMed

 12985.

Ty3 reverse transcriptase adopts an asymmetric homodimeric architecture whose assembly is substrate dependent. (Ty3) (Mus musculus) PubMed

 12986.

The 3'-end of the guide strand dynamically anchors at and releases from the PAZ domain of Argonaute; the 3'-end anchoring of the guide strand greatly accelerates the target dissociation by destabilizing the guide-target duplex. [Argonaute] (Mus musculus) PubMed

 12987.

The measured d(Fe-Fe) = 2.78 A separation in the Fe2(III/IV) intermediate, X, from Escherichia coli ribonucleotide reductase is fully consistent with computational models containing a (mu-oxo)2-Fe2(III/IV) core.[ribonucleotide reductase] (Mus musculus) PubMed

 12988.

OsGA20ox3 regulates not only plant stature but also disease resistance in rice. [OsGA20ox3] (Mus musculus) PubMed

 12989.

In this study, we describe the isolation of the opgE gene encoding the phosphoethanolamine transferase by a screen previously used for the isolation of the opgB gene encoding the phosphoglycerol transferase. (Mus musculus) PubMed

 12990.

Treatment of erythrocyte ghosts shows that the FIKK kinase Fk4.1 phosphorylates dematin, a cytoskeletal protein found at the red blood cell spectrin-actin junction.[Fk4.1] (Mus musculus) PubMed

 12991.

These results suggest a novel function for SHATI, which may be a new member of the microtubule-associated protein family. (Mus musculus) PubMed

 12992.

Data from juvenile female striped sea-bass treated with kiss1/kiss2 implants suggest that kisspeptins have opposite effects on maturation of hypothalamo-hypophyseal axis; kiss1 stimulates maturation, kiss2 inhibits maturation. [kiss-2, kisspeptin-2] (Mus musculus) PubMed

 12993.

Similar phenotypes with respect to filamentous and polar growth, vacuolar morphology, as well as the motility of early endosomes corroborate the genetic interaction between Num1 and Kin1 (Mus musculus) PubMed

 12994.

[ROM3] t EtROM3 was an active protease and involved in the cleavage of EtMIC4 (Mus musculus) PubMed

 12995.

The Hst3 degron contains two canonical Cdc4 phospho-degrons, and the phosphorylation of each of these is required for efficient turnover both in an unperturbed cell cycle and in response to replication stress.[Hst3, Cdc4] (Mus musculus) PubMed

 12996.

Prefolded BamA, the evolutionarily conserved, central subunit of the BAM complex, accelerates outer membrane protein folding by lowering the kinetic barrier imposed by phosphoethanolamine head groups.[BamA] (Mus musculus) PubMed

 12997.

ZmNIP1;1 transcript abundance increased under infestation while expression of a new aquaporin, ZmPIP2;8 and ZmTIP2;2 expression did not change.[ZmPIP2;8] (Mus musculus) PubMed

 12998.

The processing of Atg32 by Yme1 acts as an important regulatory mechanism of cellular mitophagy activity.[Atg32, Yme1] (Mus musculus) PubMed

 12999.

HrpG and HrpX activate the expression of avrAC. [avrAC] (Mus musculus) PubMed

 13000.

BcLTF1 is required to cope with oxidative stress that is caused either by exposure to light or arising during host infection. (Mus musculus) PubMed

 13001.

PGase-1 consists of 1,725 bp and hydrolyzes glycosides of steroidal saponins.[PGase-1] (Mus musculus) PubMed

 13002.

The results suggest that the stability of ICP0 is mediated by the UL13 protein kinase and that the target of proteolysis is a site at or near the RING domain of ICP0.[ICP0] (Mus musculus) PubMed

 13003.

The epi-isozizaene synthase utilizes the universal achiral isoprenoid substrate, making EIZS an ideal platform for the exploration of fidelity and promiscuity in a terpenoid cyclization reaction.(epi-isozizaene synthase) (Mus musculus) PubMed

 13004.

This study demonstrates that OsFH1 could be involved in preventing submergence-induced inhibition of root hair growth.[OsFH1] (Mus musculus) PubMed

 13005.

The two types (kinase, RNAse) of functionally disrupted OsIRE1 proteins behave as competitive inhibitors toward the endoplasmic reticulum stress response in transgenic rice plants.[OsIRE1] (Mus musculus) PubMed

 13006.

V. cholerae OmpU may have a differential regulatory role in terms of host immunomodulatory function [OmpU] (Mus musculus) PubMed

 13007.

IDD10 is a transcriptional activator involved in nitrogen regulatory circuits that control a broad spectrum of gene expression, which might influence root growth in rice.[IDD10] (Mus musculus) PubMed

 13008.

The reports a novel member from Entamoeba histolytica,RabX3,which harbors two GTPase domains in tandem and exhibits unique biochemical properties. The RabX3 binds to a single guanine nucleotide through its N-terminal domain.(RabX3) (Mus musculus) PubMed

 13009.

substitution of the conserved glutamate residue by lysine in the dimerization domain induces separation of the two DNA binding domains from their native-like positioning without altering the dimeric status of HapR variant.[HapR] (Mus musculus) PubMed

 13010.

carbon catabolic repression (CCR) operates on the agmatine deiminase system via a mechanism that involves interaction of CcpA and AguR.[AguR, ccpA, agmatine deiminase] (Mus musculus) PubMed

 13011.

The glycine-rich loop acts as a precisely balanced structural element, holding the MPP subunits in a partially closed conformation regardless the presence or absence of a substrate in the active site.[MPP] (Mus musculus) PubMed

 13012.

Wild-type Irc20 associated with Cdc48 and an increased association of the Irc20 mutant with SUMO, is reported.[Cdc48, Irc20, SUMO] (Mus musculus) PubMed

 13013.

HIV-gp120 induces and regulates mucus formation in the airway epithelial cells through the CXCR4-alpha7-nAChR-GABAAR pathway.[gp120] (Mus musculus) PubMed

 13014.

This work has identified and characterized a novel P. falciparum adhesin involved in erythrocyte invasion.[PfMA] (Mus musculus) PubMed

 13015.

Conformational changes in Dfi1p in response to environmental conditions encountered during growth allow the protein to bind calmodulin and initiate a signaling cascade that activates Cek1p.[Calmodulin, Dfi1p] (Mus musculus) PubMed

 13016.

These results strongly support that PfOrc1 may have a role in telomere silencing in this parasite.[Orc1] (Mus musculus) PubMed

 13017.

These results identify a membrane-associated mitochondrial AAA+/FtsH protease as a candidate regulatory protein for organelle biogenesis in P. falciparum.[FtsH] (Mus musculus) PubMed

 13018.

that FAM20C is not a constituent of the enamel extracellular matrix and functions intracellularly within ameloblasts.[FAM20C] (Mus musculus) PubMed

 13019.

Mature SUB3 proteolysed PRF in a dose-dependent manner. [SUB3] (Mus musculus) PubMed

 13020.

function of nonribosomal peptide synthetase AspA from Aspergillus alliaceus [AspA] (Mus musculus) PubMed

 13021.

PspA contributed to meningitis while PspC had limited importance in the disease. [PspA, PspC] (Mus musculus) PubMed

 13022.

The structural basis for 30S recognition by the novel plasmid-mediated aminoglycoside-resistance ribosomal RNA methyltransferase A (NpmA), is reported.[NpmA] (Mus musculus) PubMed

 13023.

study presents a 2.6 A resolution crystal structure of CofJ, revealing a large beta-sandwich protein; CofJ binds to lipid vesicles and epithelial cells, suggesting a role in membrane attachment during ETEC colonization (Mus musculus) PubMed

 13024.

Authors were able to show that in a virus-free system that the Chikungunya virus capsid protein contains both, a nuclear localization signal and a nuclear export signal, and that it is actively transported between the cytoplasma and the nucleus. (Mus musculus) PubMed

 13025.

Overexpression of OsWRKY76 in rice plants resulted in drastically increased susceptibility to Magnaporth oryzae, but improved tolerance to cold stress. [WRKY76] (Mus musculus) PubMed

 13026.

CTR-9 is a component of the PAF1 complex with roles in embryonic epidermal morphogenesis, including epidermal cell positioning, ventral enclosure and epidermal elongation [CTR9] (Mus musculus) PubMed

 13027.

HOPS facilitates membrane fusion by recruiting Vam7p for fusion.[Vam7] (Mus musculus) PubMed

 13028.

Sti1 is an Hsp70 cochaperone that regulates the spatial organization of amyloid-like proteins.[Sti1] (Mus musculus) PubMed

 13029.

Asp44 is able to determine two important properties of the M2 proton channel. (Mus musculus) PubMed

 13030.

Dynein and ODA10p fractions are able to bind individually to oda10 axonemes.[ODA10, dynein] (Mus musculus) PubMed

 13031.

Solanum tuberosum Remorin1.3 does not impair the silencing suppressor activity of TGBp1, but affects its ability to increase plasmodesmata permeability. [TGBp1] (Mus musculus) PubMed

 13032.

HPV6 E7 oncoprotein increases production of the IL18BP in keratinocytes.[E7] (Mus musculus) PubMed

 13033.

The ccNiR does not catalyze disproportionation because the electron-donating hydroxylamine does not poise the enzyme at a sufficiently low potential to stabilize the putative dehydrated hydroxylaminere. (Cytochrome c nitrite reductase) (Mus musculus) PubMed

 13034.

Rng8 and Rng9 form oligomers and cluster multiple Myo51 dimers to regulate Myo51 localization and functions during fission yeast cytokinesis. (Mus musculus) PubMed

 13035.

Periplasmic disulfide isomerase (DsbC) is involved in the Reactive Oxygen Spieces scavenge activity of copper binding protein (CueP). [DsbC, CueP] (Mus musculus) PubMed

 13036.

The virB1-89K gene plays an important role in the pathogenesis of S. suis 2 infection.[virB1-89K] (Mus musculus) PubMed

 13037.

These studies showed that 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase (DAHP) belongs to a family of mononuclear iron-containing enzymes that are disabled by oxidative stress.[DAHP] (Mus musculus) PubMed

 13038.

this study showed that show that overproduction of Escherichia coli MraZ inhibited cell division and was lethal in rich medium at high induction levels and in minimal medium at low induction levels.[mraZ] (Mus musculus) PubMed

 13039.

The function of MET1b, a DNA methyltransferase, in the embryonic development of Oryza sativa is reported.[MET1b] (Mus musculus) PubMed

 13040.

A narrow leaf mutant was isolated from transgenic rice (Oryza sativa L.) characterized by narrow leaves during its whole growth period, and was named nal9 (narrow leaf 9).[Nal9] (Mus musculus) PubMed

 13041.

CTR2 is involved in the ethylene-receptor signalling and regulation of various aspects of rice growth and development. [CTR2] (Mus musculus) PubMed

 13042.

Data indicate that analysis of recombinant enzymes showed that Data iindicate that Arabidopsis ISA1 requires ISA2 as a partner for enzymatic function, whereas maize ISA1 was active by itself: [ISA1 or ZmISA1] (Mus musculus) PubMed

 13043.

MRB11870 is a critical component of the mitochondrial RNA binding 1 complex core, essential for its structure and function. [MRB11870] (Mus musculus) PubMed

 13044.

It binds by the flexible side chains in the alternative binding mode in NTPDase1 allows for equally good positioning of ATP and ADP with increased activity toward ADP relative to what is seen in the case of NTPDase3.(NTPDase1) (Mus musculus) PubMed

 13045.

the vaccinia virus envelope protein A27 binding to A17 affects two important biological stages as follows: the virion assembly/egress stage (i.e. plaque size), and the infection pathways of the virus progeny (endocytosis versus plasma membrane fusion).[A27] (Mus musculus) PubMed

 13046.

polymorphism at position 400 in the connection subdomain of HIV-1 reverse transcriptase affects sensitivity to NNRTIs and RNaseH activity [reverse transcriptase] (Mus musculus) PubMed

 13047.

RMC is involved in regulation of iron acquisition. [RMC] (Mus musculus) PubMed

 13048.

natural mutations in RFT1 provide flowering time divergence under long-day conditions (Mus musculus) PubMed

 13049.

Only viruses with NIb relocated to the first two intercistronic positions were viable in tobacco plant. [NIb] (Mus musculus) PubMed

 13050.

HSF-1 acts as an essential longevity factor that intersects both insulin/IGF-1 signaling and TOR signaling pathways.[HSF-1] (Mus musculus) PubMed

 13051.

OsPUP7 has an important role in the transport of cytokinin, thus affecting developmental process and stress responses.[OsPUP7] (Mus musculus) PubMed

 13052.

These results suggest that the tRNA 3' processing activity of OsaTRZ2 contributes to chloroplast biogenesis.[OsaTRZ2] (Mus musculus) PubMed

 13053.

miR-365a cluster controls progression of epidermal squamous cell carcinoma. (Mus musculus) PubMed

 13054.

CydX is a subunit of purified Escherichia coli cytochrome bd oxidase and is needed either for the assembly or the stability of the active site di-heme center. [CydX] (Mus musculus) PubMed

 13055.

S. aureus encodes both the direct and indirect routes for Asn-tRNA(Asn) formation while encoding only one aspartyl-tRNA synthetase. [AspRS] (Mus musculus) PubMed

 13056.

model proposed in which the N-terminal moiety of NEP exerts an inhibitory function by back-folding to the C-terminal domain; in this model, adaptive NEP mutations decrease binding between the C- and N-terminal domains allowing the protein to "open up" and become active already at low temperature [NEP] (Mus musculus) PubMed

 13057.

these data suggest that the adhesin domain of SabA is sufficient in isolation for specific ligand binding. (Mus musculus) PubMed

 13058.

These data, together with a 2.3 A resolution crystal structure of the isolated N-terminal domain bound to Hb and small-angle x-ray scattering of free IsdH, reveal how multiple domains of IsdH cooperate to strip heme from Hb.[IsdH] (Mus musculus) PubMed

 13059.

study provided evidence of a Ser/Thr kinase mediated modification involved in the regulation of VraR activity in S. aureus [Stk1] (Mus musculus) PubMed

 13060.

this study examined the dynamics of translocation and substrate binding in complexes formed with the Y226F and Y390F mutants. (Mus musculus) PubMed

 13061.

Whereas knockdown of miRNAs causes growth arrest, concomitant knockdown of Tsc1 restores mTORC1 activity and proximal tubular size.[Tsc1] (Mus musculus) PubMed

 13062.

These studies showed that deoxycytidine deaminase (DCD)-deficient mutants of Escherichia coli are hypersensitive to killing by exogenous cytidine, adenosine, or guanosine, whereas wild-type cells are not. (Mus musculus) PubMed

 13063.

the conserved Fe-S protein-diflavin reductase complex, Dre2-Tah18, plays a critical role in RNR cofactor biosynthesis.[Dre2, Tah18, RNR4] (Mus musculus) PubMed

 13064.

The NRAT1 gene or its orthologs may be useful tools for enhancing Al tolerance in a wide range of plant species.[NRAT1] (Mus musculus) PubMed

 13065.

LRP1-deficient cells are not able to take up TpeL and are not intoxicated.[TpeL] (Mus musculus) PubMed

 13066.

biochemical analysis of NolR reveals protein-DNA interactions with an asymmetric operator site.[NolR] (Mus musculus) PubMed

 13067.

The natural allelic variations of three homoeologous loci Rht-A1, Rht-B1, and Rht-D1 in Chinese wheat, were analyzed.[Rht-1] (Mus musculus) PubMed

 13068.

Hei10 integrates signals from the synaptonemal complex, associated recombination complexes, and the cell cycle to mediate both the development and programmed turnover/evolution of recombination complexes via SUMOylation/ubiquitination (Mus musculus) PubMed

 13069.

GPEET mRNA is exceptionally stable in early procyclic forms, with a half-life >6h. [GPEET] (Mus musculus) PubMed

 13070.

The surface-displayed enolase, which serves as major pneumococcal plasminogen receptor, was identified as a key factor for plasminogen-mediated bacterial attachment in infection analyses with Streptococcus pneumoniae.[enolase] (Mus musculus) PubMed

 13071.

CATP-6 probably acts as a non-essential upstream positive regulator of GEM-1 [GEM-1] (Mus musculus) PubMed

 13072.

These studies identify an important role for Scx in regulating proteoglycans in embryonic and mature valve cells. (Mus musculus) PubMed

 13073.

Data show that the MtChit5 protein lacks chitinase activity but efficiently hydrolyzes bacterial nodulation factors (NFs) and renamed MtChit5 to MtNFH1 (for M. truncatula Nod factor hydrolase1: [MtNFH1] (Mus musculus) PubMed

 13074.

The interaction surfaces were experimentally identified to be the (212)SPAGARYE(219) sequence of DAHP synthase and the (60)SGGTR(64) loop and C-terminus ((97)RGKLG(101)) of chorismate mutase.[DAHP synthase, chorismate mutase] (Mus musculus) PubMed

 13075.

EndoS is composed of five distinct protein domains, including glycosidase, leucine-rich repeat, hybrid Ig, carbohydrate binding module, and three-helix bundle domains, arranged in a distinctive V-shaped conformation. (EndoS) (Mus musculus) PubMed

 13076.

Monitoring elongation complexes containing RNAPII and combinations of TFIIF and TFIIS to mechanical loads, found that both factors are independently capable of restoring arrested RNAPII to productive elongation. (TFIIS and RNAPII) (Mus musculus) PubMed

 13077.

the CasA subunit of Cascade functions as an essential partner of Cas3 by recognizing DNA target sites and positioning Cas3 adjacent to the protospacer asjacent motif to ensure cleavage (Cas3) (Mus musculus) PubMed

 13078.

Data sugget that Sec16 does not organize COPII but regulating COPII turnover for the influence of tER sites: [Sec16] (Mus musculus) PubMed

 13079.

Circumstantial evidence suggests that SpdA may contribute insulating 3', 5'cAMP-based signaling from 2', 3' cyclic nucleotides of metabolic origin.[SpdA] (Mus musculus) PubMed

 13080.

The LOV protein of Xanthomonas citri subsp. citri plays a significant role in the counteraction of plant immune responses during citrus canker. [Xcc-LOV] (Mus musculus) PubMed

 13081.

Activation of the SrrAB regulon allows Staphylococcus aureus to maintain energy production and essential biosynthetic processes, repair damage, and detoxify NO. in diverse host environments.[SrrA, SrrB] (Mus musculus) PubMed

 13082.

Papst1 mutant phenotype is caused by a single repressive gene [papst1] (Mus musculus) PubMed

 13083.

The lipid transfer protein N5 participates in linking the progression of Sinorhizobium invasion with restricting the competence of root hairs for infection (N5 protein). (Mus musculus) PubMed

 13084.

PGRN inhibits adipogenesis in porcine preadipocytes partially through ERK activation mediated PPARgamma phosphorylation.[Progranulin] (Mus musculus) PubMed

 13085.

Immunohistochemistry was found to be a reliable technique for the detection of cancer stem cells expressing CD44 or CD24 in canine mammary neoplasms, and the frequency of these cells positively correlates with grades II and III tumors.[CD24] (Mus musculus) PubMed

 13086.

The nce102Delta mutant displayed a unique phenotype in that it was defective in forming hyphae and invading low concentrations of agar but could invade well in higher agar concentrations.[nce102] (Mus musculus) PubMed

 13087.

Results indicate that the XIST gene is expressed exclusively in female cells, which is influenced by the lower level of CpG methylation in the putative promoter region compared with male cells: [XIST] (Mus musculus) PubMed

 13088.

TDY1 and TDY2 might interact to promote symplastic transport of both solutes and developmentally instructive macromolecules during vascular development at the companion cell/sieve element interface. [Tdy1] (Mus musculus) PubMed

 13089.

WRKY45 is regulated by MAPK-dependent phosphorylation in the salicylic acid pathway [WRKY45) (Mus musculus) PubMed

 13090.

transcriptional repressor that regulates its own expression through direct binding to several sites within its own promoter [NIGT1] (Mus musculus) PubMed

 13091.

Authors mapped the epitope of monoclonal antibody 4D10 to amino acid residues 14 to18 of Dengue virus 1-4 prM and found that this epitope was infection-enhancing.[prM] (Mus musculus) PubMed

 13092.

Md-miRLn11 regulates Md-NBS gene expression in particular under the condition of pathogen infection [NBS] (Mus musculus) PubMed

 13093.

The plp gene of Vibrio anguillarum encoding a phospholipase with A2 activity is specific for phosphatidylcholine and, therefore, able to lyse fish erythrocytes, but not sheep erythrocytes.[plp] (Mus musculus) PubMed

 13094.

On binding to actin at the start of the power stroke the myosin cross-bridge takes on the rigor configuration at the actin interface.[Myosin II] (Mus musculus) PubMed

 13095.

The study describes structure determination of phi6 major capsid protein P1. Electron density map corresponding to a P1 pentamer was excised from a previously determined cryoEM reconstruction of the procapsid at 7 A resolution.[capsid protein P1] (Mus musculus) PubMed

 13096.

Root apical meristem (RAM) maintenance and late metaxylem development are probably controlled by the mutual regulation between FCP2 and QHB. [FCP2; QHB] (Mus musculus) PubMed

 13097.

The results show that the invariant water molecules and ion pairs may be involved in maintaining the structural architecture, dynamics and function of the Endo-1,4-Xylanase II. [Endo-1,4-Xylanase II] (Mus musculus) PubMed

 13098.

Bacteria-derived flavins play a role in communication between rhizobia and the legume host and that the RibBA protein is important in this communication process even though it is not essential for riboflavin biosynthesis and symbiosis (RibBA). (Mus musculus) PubMed

 13099.

Identification of an active mouse antisense L1 promoter within L1 open reading frame-1 (L1 open reading frame-1). (Mus musculus) PubMed

 13100.

study describes the urea transport mechanism at atomic resolution, revealed by unrestrained microsecond equilibrium molecular dynamics simulations of the hexameric channel assembly [reI] (Mus musculus) PubMed

 13101.

results reveal the molecular mechanism underlying KaiC's regulation from the perspective of its hexameric structure; findings indicate KaiC intersubunit communication facilitates robustness of circadian rhythms. [KaiC] (Mus musculus) PubMed

 13102.

Here, we show that the transcription factor E93 is the key determinant that promotes adult metamorphosis in both hemimetabolous and holometabolous insects, thus acting as the universal adult specifier. [E93] (Mus musculus) PubMed

 13103.

Sap6 protein displays a significant function involving in maintenance the cell surface integrity.[Sap6] (Mus musculus) PubMed

 13104.

Our results demonstrate the relevance of Aegyptin for A. aegypti blood feeding, providing further support for the hypothesis that platelet aggregation inhibition is a vital salivary function in blood feeding arthropods.[aegyptin] (Mus musculus) PubMed

 13105.

The results suggest that alg3 is critical for growth, sporulation, pigment production, and protein secretion in Aspergillus niger.[alg3] (Mus musculus) PubMed

 13106.

findings suggest that non-coding RNA RsmZ is well-tuned to sequester, store and release RsmE and therefore can be viewed as an ideal protein 'sponge' [RsmZ & RsmE] (Mus musculus) PubMed

 13107.

Using (15)N solid-state NMR, the study showed protonation and H-bonded states of the cofactor pyridoxal 5'-phosphate linked as an internal aldimine in alanine racemase, aspartate aminotransferase, and poly-L-lysine. [aspartate aminotransferase] (Mus musculus) PubMed

 13108.

In this study, NMR spin relaxation experiments and molecular dynamics simulations are used to measure the dynamics of the side chain amide and carboxyl groups, (13)C(gamma/delta), in Escherichia coli ribonuclease HI. [ribonuclease HI] (Mus musculus) PubMed

 13109.

These results indicate that two Ustilago maydis velvet family members, umv1 and umv2, are important for normal teliospore development and disease progression in maize seedlings.[umv1, umv2] (Mus musculus) PubMed

 13110.

The MtCEP1 peptide modulates lateral root and nodule development in Medicago truncatula. (Mus musculus) PubMed

 13111.

These findings enrich our understanding of the biological functions of OsARF12, which also acts in regulating Pi homeostasis. [OsARF12] (Mus musculus) PubMed

 13112.

MKT1 interacts with multiple RNA-binding proteins and other potential RNA regulators, placing it at the centre of a post-transcriptional regulatory network (MKT1). (Mus musculus) PubMed

 13113.

Molecular dynamic simulation of lysine-, arginine-, ornithine-binding protein in explicit water was performed for 1 mus, and the obtained trajectory of C(alpha) atoms in the backbone was analyzed. [lysine-, arginine-, ornithine-binding protein] (Mus musculus) PubMed

 13114.

These data demonstrate that human endogenous retrovirus-K(HML-2) release is predominantly mediated through a consensus PTAP motif and two auxiliary YPX(n)L motifs in the p15 protein of the Gag precursor.[Gag] (Mus musculus) PubMed

 13115.

these data suggest that C. elegans wild isolates of varying geographic origins may adapt to environmental challenges through COX1 mtDNA variation to modulate critical aspects of mitochondrial energy metabolism. [mtDNA-encoded COX1 core catalytic subunit of mitochondrial complex IV (CIV)] (Mus musculus) PubMed

 13116.

gp120 injures neurons via an increase of NR2B and a decrease of PSD-95 expressions [gp120] (Mus musculus) PubMed

 13117.

this study identified the histone variant H2A.Z as a critical factor to modulate cohesin dynamics, and cells lacking H2A.Z suppress the mitotic defects conferred by Smc5/6 dysfunction.[H2A.Z] (Mus musculus) PubMed

 13118.

As mechanisms of HTLV-1 HBZ-mediated C/EBPalpha inhibition, authors found that HBZ physically interacted with C/EBPalpha and diminished its DNA binding capacity.[HBZ] (Mus musculus) PubMed

 13119.

The F-box and the WD40-repeat of Cdc4 are essential in inhibiting yeast-to-filament transition and flocculation. Loss of the Cdc4 N-terminal region (1-85) which impairs both the ability to flocculate and to reverse filamentous growth in C. albicans.[Cdc4] (Mus musculus) PubMed

 13120.

Ssp2 degrades the acceptor part of cross-linked tetratetrapeptides. Ssp1 cleaves monomeric tripeptides, tetrapeptides and pentapeptides and dimeric tetratetra and tetrapenta muropeptides on both the acceptor and donor strands. [Ssp1, Ssp2] (Mus musculus) PubMed

 13121.

In this work the structure of thiaminase II, determined by molecular replacement and refined at 2.7 A resolution to an R factor of 21.6% with one homotetramer in the asymmetric unit in the orthorhombic space group P212121, is presented. [thiaminase II] (Mus musculus) PubMed

 13122.

After mutagenizing the predicted extracellular loop of SaeS, we discovered one methionine residue (M31) was essential for the ability of S. aureus to transcribe sae target genes, including hla, lukAB/lukGH, and hlgA. [SAES] (Mus musculus) PubMed

 13123.

results suggest that rice BiP3 regulates membrane-resident pattern recognition receptor-mediated immunity [BiP3] (Mus musculus) PubMed

 13124.

Four crystal structures of the nodulin 13 protein are reported in complexes with several cytokinins, namely trans-zeatin, N6-isopentenyladenine, kinetin and N6-benzyladenine. [nodulin 13] (Mus musculus) PubMed

 13125.

Taken together, both MoCOD1 and MoCOD2 play important roles in conidiation and pathogenicity of the rice blast fungus.[COD1, COD2] (Mus musculus) PubMed

 13126.

The results of our experiments clearly suggest that efficient transcription and replication of virus genes by polymerase complex result in the higher pathogenicity in mice.[PB2] (Mus musculus) PubMed

 13127.

Virus infection induced apoptosis and caspase-3 activity were inhibited in Singapore grouper iridovirus-VP96 expressing cells compared to the control cells.[VP96] (Mus musculus) PubMed

 13128.

These results suggest that MpkB should have multiple roles in germination and viability of conidia, conidiation and autolysis through regulating the expression of vosA and brlA.[MpkB] (Mus musculus) PubMed

 13129.

Deletion of jlb1 abolished fruiting-body formation and impaired vegetative growth.[jlb1] (Mus musculus) PubMed

 13130.

Truncation mutation analyses for Yas3p revealed two regions that bound to phosphatidic acid and phosphoinositides.[Yas3] (Mus musculus) PubMed

 13131.

These data show that CP4 is an iron-induced cysteine proteinase that participates in Trichomonas vaginalis haemolysis. (Mus musculus) PubMed

 13132.

Nuclear export of HTLV-1 basic leucine-zipper factor (HBZ) is essential for its interaction with GADD34 and increased phosphorylation of S6 kinase, which is an established downstream target of the mTOR pathway.[HBZ] (Mus musculus) PubMed

 13133.

The current work has allowed physiological assessment of suggestions from structural studies on the key structural features that underlie the interaction of NCS-1 with its target proteins.[NCS-1] (Mus musculus) PubMed

 13134.

Thermus scotoductus TstI methyltransferase activity acts best at hemi-methylated sites. [TstI] (Mus musculus) PubMed

 13135.

study presents crystal structure of an Nei2 with a C-H-C-C-type zinc finger; a novel structural feature is a unique extension in the N-terminal domain of MvNei2; the function of this segment is currently unknown [Nei2] (Mus musculus) PubMed

 13136.

These data suggest that LeuB regulates gdhA expression in response to leucine levels, which may act as an important sensor of nitrogen availability.[LeuB, gdhA] (Mus musculus) PubMed

 13137.

Docs1 was localized to the plasma membrane. Docs1 might directly or indirectly regulate multiple genes involved in the proper development of root outer cell layers in rice. [Docs1} (Mus musculus) PubMed

 13138.

Authors show here that N-linked glycosylation is not essential for functional interaction of the m152 immune evasion protein with either MHC-I or RAE1.[m152] (Mus musculus) PubMed

 13139.

AirSR acts as a positive regulator in cell wall biosynthesis and turnover in Staphylococcus aureus NCTC8325.[AirSR] (Mus musculus) PubMed

 13140.

Iron-binding sensors HRZ1 and HRZ2 negatively regulate iron acquisition under conditions of iron sufficiency [HRZ1, HRZ2] (Mus musculus) PubMed

 13141.

Studies suggests ways that the bound hydrogen bonding rich water molecules bound in subsite two can potentially be used to adapt and expand ligand binding sites [cellobiose-binding protein] (Mus musculus) PubMed

 13142.

characterization of Fan1; demonstrated that Fan1 is a key component of a previously unidentified DNA interstrand cross-links (ICLs)resolution pathway; also demonstrated the existence of a third pathway of ICL repair, dependent on Pli1; predicted and validated key residues essential for Fan1 activity in ICL repair [Fan1] (Mus musculus) PubMed

 13143.

[strain not found] [CsrA] CsrA binding to the upstream portion of the 5' untranslated region of Escherichia coli pgaA mRNA unfolds a secondary structure that sequesters an entry site for Rho, resulting in premature stop of transcription (Mus musculus) PubMed

 13144.

Oxidation sensing is a component of the quorum-sensing agr signaling system and it is justified to analyze the influence of the agr locus, its functionality and polymorphism on S. aureus susceptibility to photodynamic inactivation. (Agr protein) (Mus musculus) PubMed

 13145.

Using interaction assays, authors found that dengue virus NS2B/3 interacts with the cellular IkappaB kinase epsilon (IKKepsilon).[NS2B/3] (Mus musculus) PubMed

 13146.

Natural variation in rly flowering1 (EL1) contributes to early heading for rice adaptation to long day in temperate and cooler regions. (Mus musculus) PubMed

 13147.

Taken together, the current data suggested that VP19 represented a conserved envelope protein in iridovirus, and might contribute greatly to virus assembly during virus infection.[VP19] (Mus musculus) PubMed

 13148.

Formaldehyde detoxification system by Ald and mycothiol-dependent FadH is essential for tolerance of Corynebacterium glutamicum to external stress by free formaldehyde in its habitat and for growth with natural substrates like vanillate.[Ald, FadH] (Mus musculus) PubMed

 13149.

Authors speculate that PfTKL2 functions may include an immunomodulatory role promoting parasite survival in the human host.[PfTKL2] (Mus musculus) PubMed

 13150.

Salmonella enterica serovar Typhimurium virulence-resistance plasmids carry nonconventional class 1 integrons with dfrA12 gene in their variable region and sul3 in the 3' conserved segment. [dfrA12],[sul3] (Mus musculus) PubMed

 13151.

Pollen tube blocked (PTB)1 is an important maternal sporophytic factor of pollen tube growth and a key modulator of rice panicle seed setting rate [PTB1] (Mus musculus) PubMed

 13152.

GOLLUM is required for balancing the production of energy-related metabolites and regulates hypoxia-induced genes. [GOLLUM] (Mus musculus) PubMed

 13153.

The rEhCBP30 and rEhCBP30-CHP proteins are able to induce an effective immune response that may protect hamsters against ALA development. (Mus musculus) PubMed

 13154.

Results propose that the different binding affinities of FlhA C-terminal for many chaperone/substrate complexes may confer an advantage for the efficient formation of the junction and cap structures at the tip of the hook prior to filament formation. (Mus musculus) PubMed

 13155.

S. enterica hilD 3'UTR is a cis-acting element that contributes to cellular homeostasis by promoting hilD mRNA turnover. [HilD] (Mus musculus) PubMed

 13156.

Results suggest group A mitogen-activated protein kinase kinase gene ZmMKK1 (BT065734) played a crucial role in chilling stress and pathogen defense in plants: [ZmMKK1] (Mus musculus) PubMed

 13157.

Data suggest that a partial deficiency of chloroplastic ascorbate peroxidases OsAPX7 (LOC_Os04g35520) and OsAPX8 (LOC_Os02g34810) genes expression modulate the PSII activity and integrity: [OsAPX7 and OsAPX8] (Mus musculus) PubMed

 13158.

a novel gene Eimeria-conserved protein (ECP) was cloned and characterized; results indicate the ECP gene has an important role in host cell invasion and development of the first generation merogony of E. tenella [ECP] (Mus musculus) PubMed

 13159.

During early chicken embryonic development, alpha5 integrin is highly expressed in cranial neural folds and migrating neural crest cells. [alpha5 integrin - ITGA5] (Mus musculus) PubMed

 13160.

Results show that GlgC had ADP-Glc PPase activity, whereas GlgD was inactive indicating that ADP-Glc PPase is an allosteric regulatory enzyme exhibiting sensitivity to modulation by key intermediates of carbohydrates metabolism. [glgC] and [glgD]. (Mus musculus) PubMed

 13161.

Notably, a mutant carrying an insertion in tsiV3, encoding immunity to a bacteriocidal type VI secretion system (T6SS) effector VgrG3, exhibited a colonization defect.[tsiV3] (Mus musculus) PubMed

 13162.

Patterns suggest that GpsB, like Pbp2x, mediates septal ring closure. [GpsB] (for guiding PBP1 shuttling) is a cell cycle protein. [Pbp2x] is a transpeptidase. (Mus musculus) PubMed

 13163.

Evidence shows that C. glutamicum RodA is not essential for viability; however, it causes an unambiguous phenotype and alters the growth rate. Also, RodA interacts wth DivIVA.[RodA] (Mus musculus) PubMed

 13164.

Results show the first characterization of a fungal beta-galactofuranosyltransferase GFsA, which was shown to be involved in Galf antigen biosynthesis of O-glycans in the Golgi. [GfsA] (Mus musculus) PubMed

 13165.

Results show the first characterization of a fungal beta-galactofuranosyltransferase GFsA, which was shown to be involved in Galf antigen biosynthesis of O-glycans in the Golgi. [GfsA] (Mus musculus) PubMed

 13166.

Data strongly indicate the participation of LmHus1, LmRad9 and LmRpa1 in the Leischmania major DNA damage response and suggest their involvement in genome maintenance mechanisms. [LmRad9], [LmHus1] and [LmRpa1] (Mus musculus) PubMed

 13167.

SERF1 is a negative regulator of grain filling and gibberellin-mediated seedling establishment in rice. (SERF1) (Mus musculus) PubMed

 13168.

OsEBS, a new QTL that controls rice biomass and spikelet number may have utility in improving grain yield in rice. [OsEBS] (Mus musculus) PubMed

 13169.

findings show increased expression of norB can be a factor that contributes to ciprofloxacin resistance in MRSA strains [norB] (Mus musculus) PubMed

 13170.

study compared responsiveness of SoxRs from Streptomyces coelicolor, Pseudomonas aeruginosa and E. coli towards redox-active compounds; ScSoxR is the most limited in the range of chemicals to which it responds and has highest reduction potential; both kinetic and redox potential factors determine range of effective chemicals[SoxR] (Mus musculus) PubMed

 13171.

IQGAP Rng2, an indispensable element of CR, was implicated in maintenance of the F-actin-independent fraction of myosin-II, whereas anillin Mid1 was required for assembly but not for maintenance of the fraction.[IQGAP] (Mus musculus) PubMed

 13172.

This work will be a good starting point for further determination of the biological role of cytosolic insect theta class GSTs and will aid the design of structure-based inhibitors. (Mus musculus) PubMed

 13173.

S. aureus sRNA SprX (small pathogenicity island RNA X) shapes bacterial resistance to glycopeptide antibiotics and controls SpoVG expression (SprX). (Mus musculus) PubMed

 13174.

The Sbi immune evasion protein is a target for RNAIII (Sbi, RNAIII). (Mus musculus) PubMed

 13175.

This study reports that normal, high-efficiency expression of the methionine synthase gene (met-8) requires the presence of a proximal 50-kb AT-rich region of heterochromatin in N. crassa. (Mus musculus) PubMed

 13176.

Dnmt2 specifically methylates Geobacter tRNAGlu in vitro and in vivo and not Geobacter tRNAAsp (Dnmt2). (Mus musculus) PubMed

 13177.

CPK1 is the major PKA catalytic subunit gene and that the cAMP-PKA pathway plays critical roles in hyphal growth, conidiation, ascosporogenesis, and plant infection in F. graminearum. [CPK1] (Mus musculus) PubMed

 13178.

ZmRFP1 confers drought stress tolerance in transgenic tobacco not only by increasing the ability to retain water, but also by reducing ROS accumulation and membrane damage through enhancing the antioxidant system. [RFP1] (Mus musculus) PubMed

 13179.

protein-protein interactions between FtsK and XerD help prevent removal of XerCD from DNA by promoting rapid reversal of FtsK. [Ftsk protein, E coli] (Mus musculus) PubMed

 13180.

IkappaBL was found to regulate the CLK1-dependent synthesis of M2 RNA, a splice variant of influenza A virus M gene.[M2 RNA, a splice variant of influenza A virus M gene.] (Mus musculus) PubMed

 13181.

Cytological analysis revealed that the moderate resistance controlled by RmgTd(t) was associated with a hypersensitive reaction of mesophyll cells. [RmgTd(t)] (Mus musculus) PubMed

 13182.

the avian SLAMF4(CD244, 2B4), expression markedly differs from mammals; it binds to SLAMF2 and will be an important tool to discriminate several gammadelta T cell subsets.[SLAMF2] (Mus musculus) PubMed

 13183.

Oncorhynchus mykiss peptidoglycan recognition protein has an anti-inflammatory function, independent of its amidase activity, possibly via NF-kappaB inhibition in liver cells.[peptidoglycan recognition protein] (Mus musculus) PubMed

 13184.

These results suggested that cagA and vacA gene expression is upregulated in Helicobacter pylori, especially by host cell contact, and Fur has a role in the upregulation.[CagA] (Mus musculus) PubMed

 13185.

Data indicate that targeted gene deletion of MET13 methylenetetrahydrofolate reductase gene resulted in mutants that were non-pathogenic and significantly impaired in aerial growth: [MET13] (Mus musculus) PubMed

 13186.

RGB1(I) plays an active and significant role in the regulation of abiotic stresses in rice [RGB1] (Mus musculus) PubMed

 13187.

The structural and dynamic properties of SaMazF are compared to other MazF family members (SaMazF). (Mus musculus) PubMed

 13188.

A trans-encoded sRNA RalA (for RalR antitoxin), functions as an antitoxin for RalR (RalA). (Mus musculus) PubMed

 13189.

Collectively, our results indicate that rice OsCPK10 is a crucial regulator in plant immune responses, and that it may regulate disease resistance by activating both SA- and JA-dependent defense responses. [OsCPK10] (Mus musculus) PubMed

 13190.

Data indicate that the double mutant lacking the conventional divinyl reductase (DVR) and chlorophyllide a reductase (COR) uniquely accumulated divinyl-chlorophyllide a: [COR] (Mus musculus) PubMed

 13191.

The reaction catalyzed by LpxA possesses a highly unfavourable equilibrium constant with no evidence of coupling to an energetically favourable reaction.(LpxC) (Mus musculus) PubMed

 13192.

Enzyme kinetics of recombinant LDH was found to be in the direction of lactate to pyruvate Km of 2.03 +/- 0.025 muM and Kcat of 1.69 +/- 0.03/min and from pyruvate to lactate Km of 1.62 +/- 0.10 muM and Kcat of 1.75 +/- 0.03/min.[LDH] (Mus musculus) PubMed

 13193.

AGAP007256, AGAP00962 and AGAP009763, and AGAP012386 are positive regulators of the mosquito antibacterial response.[AGAP00962, Nimrod] (Mus musculus) PubMed

 13194.

The study explores substrate-specific transport defects of BtuF mutants. [BtuF] (Mus musculus) PubMed

 13195.

the DEP1-RGB1 plant G protein complex regulates nitrogen signaling [DEP1, RGB1] (Mus musculus) PubMed

 13196.

Findings suggest that Gib2 promotes cAMP levels by relieving an inhibitory function of Ras1 on Cac1: [Gib2, Ras1 and Cac1] (Mus musculus) PubMed

 13197.

This study reported the novel finding that the OsHIR1 E3 ligase positively regulates OsTIP4;1 related to As and Cd uptakes.[HIR1] (Mus musculus) PubMed

 13198.

These results support a multifunctional role for RBP-P in glutelin mRNA metabolism.[RNP-P; glutelin] (Mus musculus) PubMed

 13199.

Data indicate that VgrG3C-TsaB (type VI secretion antitoxin B protein complex exits as a heterotetramer in solution: [TsaB] (Mus musculus) PubMed

 13200.

TaNHX2 is a endomembrane-bound protein and may primarily function as a K+/H+ antiporter, which is involved in cellular pH regulation and potassium nutrition under normal conditions. [TaNHX2] (Mus musculus) PubMed

 13201.

Xlox is a crucial player of cell differentiation in the sea urchin embryo [Xlox] (Mus musculus) PubMed

 13202.

3C protein might have a virulence-suppressing effect in FCoV-infected cats (3C Protein) (Mus musculus) PubMed

 13203.

The cell-end marker TeaA and the microtubule polymerase AlpA contribute to microtubule guidance at the hyphal tip cortex of Aspergillus nidulans to provide polarity maintenance. [TeaA], [AlpA] (Mus musculus) PubMed

 13204.

The tubulin cofactor C family member TBCCD1 orchestrates cytoskeletal filament formation. [TBCCD1] (Mus musculus) PubMed

 13205.

Data indicate that the kinase activity of virulence factor ROP18 is required for p65 degradation and suppresses NF-kappaB activation: [ROP18] (Mus musculus) PubMed

 13206.

A truncated thioredoxin from Cynoglossus semilaevis, CsTrx1, CsTrx80, which is composed of the N-terminal 80 residues of CsTrx1, possesses chemotactic and immunoregulatory properties which promote host resistance against bacterial infection.[Trx80] (Mus musculus) PubMed

 13207.

[HSP72]Correlations between HSP72 expression and ileal Lactobacillus spp. and colonic clostridia species, and between HSP27 expression and uronic acid ingestion, were important (Mus musculus) PubMed

 13208.

VRN-A1 has a particular DNA methylation pattern, exhibiting rapid shift within the life cycle of a winter wheat plant following exposure to particular environmental conditions.[VRN-A1] (Mus musculus) PubMed

 13209.

(MFE-1; peroxisomal multifunctional enzyme type 2) MFE-1 contributes to the synthesis of mature bile acids in both alpha-methylacyl-CoA racemase (AMACR)-dependent and independent pathways. (Mus musculus) PubMed

 13210.

The 21-bp core sequence upstream of the Bmlp3 transcription start site is essential for the transcriptional activity of the Bmlp3 promoter. (Mus musculus) PubMed

 13211.

Expression of the Neurospora crassa tcu-1 gene (NCU00830), encoding a high-affinity copper transporter, is tightly controlled by copper availability.[tcu-1] (Mus musculus) PubMed

 13212.

This study has identified a novel MYB transcription factor MdMYB3, in the apple genome.[MdMYB3] (Mus musculus) PubMed

 13213.

PpHsp16.4 localized in cytosolic granules in the vicinity of chloroplasts under non stress conditions, suggesting possible distinct roles for this protein under stress and optimal growth.[PpHsp16.4] (Mus musculus) PubMed

 13214.

Results suggest that ChiS operates a chitin-induced non-canonical signal transduction cascade through TfoS, leading to transcriptional activation of tfoR. [ChiS] (Mus musculus) PubMed

 13215.

study reports evidence of the sequence-independent DNA-binding capacity of the varphi29 terminal protein (TP) to the B. subtilis genome, and gain insight into the secondary structure of the TP N-terminal domain, responsible for bacterial nucleoid targeting [TP] (Mus musculus) PubMed

 13216.

An analysis of BALF revealed lymphocytosis and increased expression of HTLV-I HBZ mRNA in patients with HTLV-I-associated lung disorders. (bZIP factor, HBZ) (Mus musculus) PubMed

 13217.

The present study reports the isolation and characterization of a new SUT, designated as TaSUT2, and its homeologues (TaSUT2A, TaSUT2B and TaSUT2D) in hexaploid wheat.[SUT2, SUT2A, SUT2B, SUT2D] (Mus musculus) PubMed

 13218.

study describes functional characterization of predicted copper-transporting P-type ATPase (CuTP); demonstrated CuTP is predominantly located in vesicular bodies of the parasite; demonstrated PbCuTP is dispensable for blood stage development and important only for male and female fertility (Mus musculus) PubMed

 13219.

electron cryo-microscopy to determine sub-nanometre-resolution three-dimensional reconstructions of a full-length polyketide synthase module from the bacterium Streptomyces venezuelae [PKS] (Mus musculus) PubMed

 13220.

Artemisinin resistance to P. falciparum, which is now prevalent across mainland Southeast Asia, is associated with mutations in kelch13. [kelch13] (Mus musculus) PubMed

 13221.

Combined linkage and association mapping pinpoints Zmtrx-h as the most likely positional candidate gene for Scmv1.[Scmv1] (Mus musculus) PubMed

 13222.

the cysteine-rich site near the C terminus of 2C(ATPase) is involved in encapsidation, possibly through an interaction with an upstream segment located between boxes A and B of the nucleotide-binding domain (2C(ATPase)) (Mus musculus) PubMed

 13223.

study identifies a spore-specific protein, SspA and demonstrates that the single promoter of sspA is not only dependent on sigF, but its transcription is directed by RNA polymerase holoenzyme containing SigF, which establishes sspA as a direct target for the sigma factor, SigF [sspa] (Mus musculus) PubMed

 13224.

two microRNAs (miRNAs), miR-726 and miR-729, are potentially involved in photoreceptor subtype specification. [miR-726] (Mus musculus) PubMed

 13225.

CaMNUC32, a 32 kDa Ca2+/Mg2+-dependent nuclease was identified and characterized.[CaMNUC32] (Mus musculus) PubMed

 13226.

Results demonstrate the requirement of post-translational modifications for TbAUK1 function and a crucial role of TbCPC1 in mediating TbAUK1 localization. [AUK1, CPC1 & CPC2]. (Mus musculus) PubMed

 13227.

TssK, a core component of the bacterial Type VI secretion system, has distinct oligomeric states of TssK as a part of a TssK-TssFG subcomplex. [TssK] (Mus musculus) PubMed

 13228.

OsSIK2 may integrate stress signals into a developmental program for better adaptive growth under unfavorable conditions.[OsSIK2] (Mus musculus) PubMed

 13229.

identification of cis-aconitate decarboxylase (CAD1) gene and determination of the presence of itaconate in the riboflavin biosynthetic pathway in A. gossypii were carried out to confirm itaconate metabolism [CAD1] (Mus musculus) PubMed

 13230.

Cis-element of the rice PDIL2-3 promoter is responsible for inducing the endoplasmic reticulum stress response [PDIL2-3] (Mus musculus) PubMed

 13231.

acl1 and acl2 coordinately modulate the cytoplasmic acetyl-CoA levels to regulate growth, development, and citric acid synthesis in A. niger (acl1 and acl2). (Mus musculus) PubMed

 13232.

secondary structure in the 5' untranslated region of adhE mRNA required for RNase G-dependent regulation [adhE][RNase G] (Mus musculus) PubMed

 13233.

LGD1 pleiotropically regulated rice vegetative growth and development through both the distinct spatiotemporal expression patterns of its multiple transcripts and RNA binding activity. [LGD1] (Mus musculus) PubMed

 13234.

Conjugated polyketone reductase C2 adopted a triose-phosphate isomerase barrel fold at the core of the structure.[Conjugated polyketone reductase C2] (Mus musculus) PubMed

 13235.

overexpression of mTORC1 in endothelial cells exacerbated vascular phenotypes in animals with reduced EPHB4 or RASA1, suggesting a functional EPHB4/RASA1/mTORC1 signaling axis in endothelial cells (mTORC1) (Mus musculus) PubMed

 13236.

We were able to trap polysaccharide translocation intermediates within the lumen of Wza, providing the first unequivocal evidence to our knowledge that nascent capsular polysaccharide chains exit the cell through the Wza portal.[WZA] (Mus musculus) PubMed

 13237.

The study concludes that Laccaria bicolor, in contrast to arbuscular mycorrhizal fungi and biotrophic pathogens, promotes mutualism by blocking JA action through the interaction of MiSSP7 with PtJAZ6 (MiSSP7). (Mus musculus) PubMed

 13238.

PufX itself has no influence on ordering the photochemical reaction centre-LH1 complexes. [PufX] (Mus musculus) PubMed

 13239.

OsFBK12 is involved in the 26S proteasome pathway by interacting with Oryza sativa S-PHASE KINASE-ASSOCIATED PROTEIN1-LIKE PROTEIN and it targets the substrate OsSAMS1 for degradation.[OsSAMS1, OsFBK12] (Mus musculus) PubMed

 13240.

Cj0588 protein belongs to the TlyA(I) protein family and is a rRNA methyltransferase. Methylation of ribosomal RNA catalyzed by Cj0588 appears to have an impact on the biology of the cell. (Cj0588) (Mus musculus) PubMed

 13241.

The cytotoxic bacterial intracellular prionoid RepA-WH1 exhibits a hallmark feature of amyloids, as characterized in eukaryotes: cross-aggregation between variants of the same protein.[RepA-WH1] (Mus musculus) PubMed

 13242.

This study showed that the imbalance in manganese homeostasis in the DeltahflX strain is independent of the MntR regulon.[HflX; MntR] (Mus musculus) PubMed

 13243.

These results also suggested that galK expression could be regulated through mK2 production independent from natural polarity.[galK] (Mus musculus) PubMed

 13244.

The target site of tae-miR156 in TaSPL17 was also highly conserved.[miR156, SPL17] (Mus musculus) PubMed

 13245.

Monomeric UL128 protein works as soluble chemokine analogue to attract peripheral blood mononuclear cells and plays an important role in HCMV infection. [UL128] {review] (Mus musculus) PubMed

 13246.

Collectively, the results demonstrate that critical mutations (i.e., HA-Q226L) enable the H7N9 viruses to be transmitted in a mammalian host. (Mus musculus) PubMed

 13247.

This study provides the first direct link between the alpha4-alpha4' helix pair interaction and the core protein (CP) dimer conformation that is the basis of CP function, particularly in nucleocapsid formation during virion production.[core protein] (Mus musculus) PubMed

 13248.

PlasmoDJ1, a multi-activity enzyme, supports parasite virulence and oocyst production. [PlasmoDJ1] (Mus musculus) PubMed

 13249.

Authors demonstrate that production of colibactin by Escherichia coli exacerbates lymphopenia associated with septicemia and could impair the chances to survive sepsis. (Mus musculus) PubMed

 13250.

2 genes: AmILP2 transcript levels may influence specific organ development, such as the ovary and body mass. [AmILP2] JH production may be regulated by AmILP1. [AmILP1] (Mus musculus) PubMed

 13251.

The CovSR two-component system is the core of a signaling pathway integrating the regulation of CovS by Abx1 in addition to the regulation of CovR by the serine/threonine kinase Stk1. [Abx1 and CovS] (Mus musculus) PubMed

 13252.

This is the first report for accumulation of triacylglycerol in pho88Delta and pho86Delta cells under phosphate starvation conditions.[pho88, pho86] (Mus musculus) PubMed

 13253.

The expression of the HSV-1 infection response repressive protein (HIRRP, GI 16552881) was up-regulated in human L02 cells infected with HSV-1. (HIRRP) (Mus musculus) PubMed

 13254.

[HIV gp120] Fever induced by HIV-1 glycoprotein (gp)120 is regulated by mu-type opioid receptors. (Mus musculus) PubMed

 13255.

analyzed a HD-Zip III member, Hox33, and demonstrated that it plays an important role in age-dependent leaf senescence (Hox33) (Mus musculus) PubMed

 13256.

Wor2 is not required for opaque cell formation at least under some culture conditions. Therefore C. albicans cells may adopt a different gene expression profile in response to GlcNAc to activate phenotypic switching. (Mus musculus) PubMed

 13257.

physicochemical properties of CagA [CagA] (Mus musculus) PubMed

 13258.

DegS and RseP homologous proteases are involved in singlet oxygen dependent activation of RpoE in Rhodobacter sphaeroides [DegS][RseP][RpoE] (Mus musculus) PubMed

 13259.

TaTIP2;2 probably regulates the response to stress via an ABA-independent pathway(s) [TaTIP2;2] (Mus musculus) PubMed

 13260.

NikA plays a crucial role in several aspects of A. fumigatus physiology and, to a certain extent, modulates the HOG pathway. (Mus musculus) PubMed

 13261.

These results suggest that WRKY13 regulates the antagonistic cross talk between drought and disease resistance pathways.[WRKY13] (Mus musculus) PubMed

 13262.

exposure to chronic isolation modulates mRNAs for oxytocin and vasopressin receptors in the hypothalamus and heart [V1aR] (Mus musculus) PubMed

 13263.

Castor oil seeds bacterial-type PEPC (BTPC)(RcPpc4) and plant-type PEPC (PTPC) (RcPpc3) interact in vivo as a class-2 PEPC complex that associates with the surface of mitochondria. [RcPpc3 and RcPpc4] (Mus musculus) PubMed

 13264.

Importin-alpha7 is required for enhanced virus replication in the alveolar epithelium, resulting in elevated cytokine and chemokine levels, extensive mononuclear infiltration, and thus, severe pneumonia and enhanced virulence in mice.[Importin-alpha7] (Mus musculus) PubMed

 13265.

High fat diet-induced metabolic derangements negatively affect GnRH neuron function through an inflammatory injury at the hypothalamic level.[GnRH] (Mus musculus) PubMed

 13266.

Collectively, these data characterize TfoS as a novel chitin-sensing transcriptional regulator that represents the direct link between chitin and natural competence in Vibrio cholerae.[TfoS] (Mus musculus) PubMed

 13267.

All 15 N-glycosylation sites of EBOV GP1 could be removed without compromising the expression of GP. The loss of these 15 glycosylation sites significantly enhanced pseudovirion transduction in Vero cells, which correlated with an increase in protease sensitivity.[GP1] (Mus musculus) PubMed

 13268.

Chb and CBP in combination with ChiB and ChiC (individually or together) increased their chitinase activity.[Chb, CBP, ChiB] (Mus musculus) PubMed

 13269.

Disruption of luxO was found to increase VVP production and expression of its gene vvpE and resulted in reduction of VVH production and expression of its gene vvhA.[luxO] (Mus musculus) PubMed

 13270.

Ideal plant architecture1 (IPA1) plays a key role in the regulation of plant architecture and other developmental processes. [IPA1] (Mus musculus) PubMed

 13271.

The LEM-domain protein Man1 promotes chromatin-nuclear pore complex association in mitosis (Man1). (Mus musculus) PubMed

 13272.

This indicates that CRE1 is important for correct nucleosome positioning within the cbh1 coding region under repressing conditions.[cbh1] (Mus musculus) PubMed

 13273.

Data indicate that both long-form leptin receptor (LepRL) and a truncated LepR (LepRT) receptors specifically bind leptin(Lep): [LepRL & LepRT] (Mus musculus) PubMed

 13274.

The study presents the structural characterization of the PTS enzyme I-alpha-ketoglutarate interaction and the basis for enzyme I inhibition by alpha-ketoglutarate.[PTS enzyme I] (Mus musculus) PubMed

 13275.

an essential role of ClpB in controlling protein aggregation and inclusion body formation in bacteria. [CLpB] (Mus musculus) PubMed

 13276.

The nap1Delta/Delta mutant and alleles carrying mutations of the phosphorylation sites exhibited greatly reduced virulence in a mouse model of systemic candidiasis.[Nap1] (Mus musculus) PubMed

 13277.

LytA utilizes a large substrate recognition interface and requires large muropeptide substrates with several connected saccharides that interact with all subregions of the binding crevice for catalysis.[LytA] (Mus musculus) PubMed

 13278.

Data indicate that minoglycoside aminotransferase (3') type IIIa (APH(3')-IIIa) is well-suited for the study of adaptive enzyme evolution: [APH(3')-IIIa] (Mus musculus) PubMed

 13279.

In this study, a Fus3/Kss1-type mitogen-activated protein kinase (MAPK) gene MaMk1 (GenBank accession No. EFY93607) was identified in Metarhizium acridum, which encodes a member of the YERK1 subfamily (Mus musculus) PubMed

 13280.

The Hfl1 protein regulates mitochondria and peroxisomal metabolism also is new to fungal pathogens and speaks to their regulation of organelle crosstalking.(Hfl1 protein and dbp4 protein) (Mus musculus) PubMed

 13281.

These results demonstrate that the presence of OmcS on pili is not sufficient to confer conductivity to pili and suggest that there are unique structural features of the Geobacter sulfurreducens PilA that are necessary for conductivity.[OmcS, PilA] (Mus musculus) PubMed

 13282.

The optimal pH and temperature for diacetyl reduction were pH 7.0 and 30 degrees C, whereas those for (2S,3S)-2,3-butanediol oxidation were pH 9.5 and 25 degrees C.[acetoin(diacetyl) reductase] (Mus musculus) PubMed

 13283.

MBS is a small zinc finger protein, methylene blue sensitivity, that is required for induction of singlet oxygen-dependent gene expression and, upon oxidative stress, accumulates in distinct granules in the cytosol. [MBS] (Mus musculus) PubMed

 13284.

Expression of MYB14 and MYB15 correlates with stilbene accumulation in skins and seeds of developing grape berries. (Mus musculus) PubMed

 13285.

In hyperhomocysteinemic cystathionine-beta-synthase deficient (CBS(+/-)) mice with high brain vessel permeability, miR29b levels were also high as compared with wild-type mice [microRNA29b] (Mus musculus) PubMed

 13286.

under Fe deficiency. The major distinguishing genes were NAS2, IRT2, DMAS1, and YSL15 in shoot and NAS2, IRT1, IRT2, YSL2, and ZIP8 in roots. (Mus musculus) PubMed

 13287.

OsDMI3 functions upstream of OsMPK1 to regulate the activities of antioxidant enzymes and the production of H2 O2 in rice. [DMI3] (Mus musculus) PubMed

 13288.

Bacterial adhesin fadA may be more closely related to the development of gingivitis and periodontal disease. [fadA] (Mus musculus) PubMed

 13289.

IRF-4-mediated CIITA transcription is blocked by KSHV encoded LANA to inhibit MHC II presentation. (Mus musculus) PubMed

 13290.

Protein CPAF is leading factor of pathogenesis. This protein inhibits the signaling pathways of host cell and supports long survival of the pathogen in the host cell.[review] (Mus musculus) PubMed

 13291.

The crystal structure of LpxC in complex with L-161,240 was determined at 2.1 A resolution.[LpxC] (Mus musculus) PubMed

 13292.

Oxidative stress in D. discoideum lacking caspases leads to PARP activation, followed by the release of apoptosis inducing factor from mitochondria.[PARP] (Mus musculus) PubMed

 13293.

These results indicate that neurotensin and LANT-6 are produced in the chicken brain, and they may participate in multiple functions.[LANT-6] (Mus musculus) PubMed

 13294.

methionines contribute to efficient barrel structuring and protein-lipid interactions, and are therefore important elements of OmpX stability [OmpX] (Mus musculus) PubMed

 13295.

Mossbauer, resonance Raman, and EPR spectroscopy are not able to discriminate between the imidazole-coordinated [4Fe-4S] cluster and the non-imidazole-bound [4Fe-4S] cluster with an exchangeable fourth ligand that is present in wild-type HydF. [HydF] (Mus musculus) PubMed

 13296.

Data from studies on recombinant/mutant CCP1 suggest Tyr71 is reactive intermediate in oxidation of substrate (guaiacol) binding far from heme; surface-exposed Tyr236 is more likely related to oxidative stress signals. [CCP1, cytochrome c peroxidase] (Mus musculus) PubMed

 13297.

These results suggest that the preferential OFF state observed in CS31A cells is mainly due to the weak interaction of the leucine-responsive regulatory protein with the clp distal region and that the PapI homolog favors the OFF phase.[CS31A, PapI] (Mus musculus) PubMed

 13298.

unique catalytic properties of StDAPDH [DAPDH] (Mus musculus) PubMed

 13299.

TaHsfA2d provides abiotic stress tolerance and yield enhancement in transgenic Arabidopsis under heat stress environment [TaHsfA2d] (Mus musculus) PubMed

 13300.

VopQ interacts with the Vo domain of the conserved vacuolar H+-ATPase. [VopQ] (Mus musculus) PubMed

 13301.

IE1 is a regulator of the pro-inflammatory response and a specific pathogen gene capable of moderating the host production of TNFalpha in vivo. [IE1] (Mus musculus) PubMed

 13302.

sarA plays an important role in attenuating the inflammatory response during staphylococcal biofilm infection in the CNS [sarA] (Mus musculus) PubMed

 13303.

bm47 knock-out had no significant effect on viral DNA replication but significantly decreased the transcription levels of early gene. (Mus musculus) PubMed

 13304.

Conditional knockdown of TgARO recapitulates the dispersed rhoptry phenotype of TgDHHC7 knockdown. [TgDHHC7 and TgARO] (Mus musculus) PubMed

 13305.

structure and function of oligopeptidase B [oligopeptidase B] (Mus musculus) PubMed

 13306.

Plasmodium berghei CDPK1 is dispensable in the parasite's erythrocytic and pre-erythrocytic stages [CDPK1] (Mus musculus) PubMed

 13307.

role of phosphodiesterase BcPde2 in growth, differentiation and virulence of Botrytis cinerea [BcPde2] (Mus musculus) PubMed

 13308.

Authors found that the V/I505T mutation in gp45 was located in a highly conserved d position within the heptad repeat, which protruded into a 3-fold symmetry axis within the six-helix bundle.[gp45] (Mus musculus) PubMed

 13309.

Data suggest correlation exists between relative affinity between subunits in AcrB trimer and drug efflux activity; a threshold trimer stability is required to maintain efflux activity toward antibacterial agents (novobiocin, erythromycin). [AcrB] (Mus musculus) PubMed

 13310.

MiR-H3 upregulates HIV-1 RNA transcription and protein expression.[Mir-H3] (Mus musculus) PubMed

 13311.

The crystal structure of NleC is reported at 1.55 A resolution. The structure reveals that NleC is a member of the zincin zinc protease family. [NleC] (Mus musculus) PubMed

 13312.

Crystallographic, mutational, biochemical studies were used to define the molecular features of the racemase BsrV that enable this enzyme to accommodate more diverse substrates than the related pyroxidal-5--phosphate - dependent alanine racemases.[BsrV] (Mus musculus) PubMed

 13313.

X-ray crystallographic studies of Endo- -1,4-xylanase II is obtained at 1.15 A resolution. Replacing amino acids near Glu177 decreased the xylanase activity but increased the relative activity at alkaline pH.[xyn2] (Mus musculus) PubMed

 13314.

Crystal structures of FbpA, the periplasmic ferric ion-binding protein of an iron-uptake ABC transporter, from Thermus thermophilus HB8 (TtFbpA) have been solved in apo and ferric ion-bound forms at 1.8 and 1.7 A resolution, respectively. [FbpA] (Mus musculus) PubMed

 13315.

Our observations suggest that the nuclear-encoded Cpn60alpha protein TCD9 plays a crucial role in chloroplast development at early leaf stage of rice. (Mus musculus) PubMed

 13316.

Further analysis suggested that the OsAGPS2b is a considerable candidate gene responsible for phenotype of sugary mutant. (Mus musculus) PubMed

 13317.

These results suggest that MsZFN primarily controls flowering time by repressing flowering genes expression under long day conditions. [MsZFN] (Mus musculus) PubMed

 13318.

In particular, the PvVRN1 gene appears to play an important role in regulating the adaptation process of common bean. [PvVRN1] (Mus musculus) PubMed

 13319.

Knockdown of endogenous Imp inhibited the male-specific splicing of the Imp minigene transcript. In contrast, overexpression of Imp in female cells induced the male-specific splicing of the Imp minigene transcript. (Mus musculus) PubMed

 13320.

The balanced redox status maintained by the thioredoxin system is essential for development and pathogenesis of Botrytis cinerea. [bctrx1; bctrx2; bctrr1] (Mus musculus) PubMed

 13321.

Gdac1 locus affects both spontaneous and Salmonella enterica serotype typhimurium-induced colitis in 129 non-double-knockout mice, although in opposite directions. [Gdac1] (Mus musculus) PubMed

 13322.

Therefore, the suggested drugs can be used as an effective treatment solving HCV NS3/4A protease drug resistance problem. (Mus musculus) PubMed

 13323.

a novel MYB coiled-coil transcription factor referred to as IPN2, for Interacting Protein of NSP2, is described.[IPN2, NSP2] (Mus musculus) PubMed

 13324.

These results suggest that polar and apolar cells have intrinsic differences that establish outer/inner configuration and differentially regulate Hippo signaling to activate lineage-specific gene expression programs.[Hippo] (Mus musculus) PubMed

 13325.

Fbxoo is associated with early oocyte development by regulating other critical proteins involved in oogenesis in rainbow trout. [Fbxoo] (Mus musculus) PubMed

 13326.

The toxic protein RIP2 is induced by caterpillar feeding and is one of a potential suite of proteins that defend maize against chewing herbivores.[RIP2] (Mus musculus) PubMed

 13327.

The N-terminal APK-rich domain and RNA recognition motif of P34 and the L18 domain of L5 are important for the association of the two proteins with each other. [P34] (Mus musculus) PubMed

 13328.

There is an essential role for PPL2 in postreplication tolerance of endogenous DNA damage, thus allowing completion of Trypanosoma genome duplication. [PPL2] (Mus musculus) PubMed

 13329.

In the parasite, the catalytic subunit of calcineurin (CaNA2) is associated with CaNB. (Mus musculus) PubMed

 13330.

CYP307A1 is required for ecdysteroid synthesis in Anopheles gambiae. [CYP307A1] (Mus musculus) PubMed

 13331.

Utilizing a computational approach, the existence of a structurally significant Carbon-donated hydrogen bond in the Streptococcus pneumoniae hyaluronate lyase is affirmed. [hyaluronate lyase] (Mus musculus) PubMed

 13332.

Aminopeptidase P was cloned, sequenced, and characterized for substrate specificity, optimal conditions, co-factors and inhibitors. APP (Mus musculus) PubMed

 13333.

The Gpx3 mediated Cap1-dependent oxidative stress responses are essential for the effective killing of macrophages by C. albicans.(Gpx3) (Mus musculus) PubMed

 13334.

Hh signaling regulates the proliferation of MF-HSCs irrespective of the action of miRNA-29, eventually contributing hepatic fibrosis, when the NF-kappaB pathway is disrupted. (Mus musculus) PubMed

 13335.

The Aes dimer adopts an antiparallel contact involving both the hydrolase core and the cap, with its twofold axis perpendicular to the largest dimension of Aes. [Aes] (Mus musculus) PubMed

 13336.

TfCel48A is able to hydrolyze the TfCel9A-modified substrate efficiently and replenish the uniform surface required by TfCel9A, creating a feedback mechanism.[Cel48A, Cel9A] (Mus musculus) PubMed

 13337.

WCI16 represents a novel class of Late embryogenesis abundant proteins and is involved in freezing tolerance.[WCI16] (Mus musculus) PubMed

 13338.

cagT, cagX, cagV, cagM, and cag3 mutants were defective in both the cag type IV secretion system function and pilus formation.[cagT, cagX, cagV, cagM, and cag3] (Mus musculus) PubMed

 13339.

LamR interaction with the yeast prion-forming protein, Sup35, was investigated.[Sup35] (Mus musculus) PubMed

 13340.

A functional non-canonical nuclear localization signal (NLS) for p10.8 was identified and mapped to N-terminus residues 1-40.[p10.8] (Mus musculus) PubMed

 13341.

Based on these results, GiPrx1a and deltaGiPrx1b are suggested to play an important role in the antioxidant defense of Giardia, possibly contributing to pathogenesis.[Prx1a, Prx1b] (Mus musculus) PubMed

 13342.

The results from these experiments do not provide support for plasma nesfatin-1 as a signal for the initiation of reproductive development in rematuring female rainbow trout.[Nesfatin-1] (Mus musculus) PubMed

 13343.

LjIPT3 gene product is required for nodule initiation and development, and does not appear to be involved in early infection events.[LjIPT3] (Mus musculus) PubMed

 13344.

These results indicate that Nel positively regulates RGC production by promoting their differentiation and survival during development. (Mus musculus) PubMed

 13345.

Authors show that the CLO3403/CLO3404 TCS of Clostridium botulinum E1 Beluga is involved in the cold shock response and growth at 12 degrees C.[CLO3403, CLO3404] (Mus musculus) PubMed

 13346.

Authors confirm that current annotation of the An. gambiae genome incorrectly identifies AgNimB2 and AgEater as a single gene, AGAP009762.[NimB2, Eater] (Mus musculus) PubMed

 13347.

Loss-of-function mutations of ONI3, which were identified as mutants with ectopic expression of KNOX genes in leaves and morphologically resembling KNOX overexpressors, showed abnormal organ fusions in developing shoots.[ONI3] (Mus musculus) PubMed

 13348.

Deletional loss of arlA, which encodes a Mig-14 family protein implicated in defensin resistance, and arlC, an OmpT family outer membrane protease sensitized strain NRG857c to these host defense molecules.[arlA, arlC] (Mus musculus) PubMed

 13349.

This study suggests the coordinated action of Hla and PSM-alpha in host tissue during early pathogenesis, confirming a major role for Hla in epithelial injury during Staphylococcus aureus infection.[Hla, Psm-alpha] (Mus musculus) PubMed

 13350.

Study demonstrates that a single 30 min exposure to glutamate down-regulates GLAST uptake activity for up to 3 h, suggesting a pivotal role of GLAST in the control of glia/neuronal interactions. [EEAT1/GLAST] (Mus musculus) PubMed

 13351.

The sec63 J-domain mutant was only defective in (endoplasmic reticulum-associated Degradation) of soluble substrates.[Sec63p] (Mus musculus) PubMed

 13352.

This study revealed that SWL1 is essential for the beginning of thylakoid membrane organization during chloroplast development.[SWL1] (Mus musculus) PubMed

 13353.

(ST405 NDM-4) ST405 NDM-4 (metallo-beta-lactamase)-producing Escherichia coli is isolated from a Danish patient hospitalized in Vietnam. (Mus musculus) PubMed

 13354.

MdDRB1 functions in the miRNA biogenesis in a conserved way and that it is a master regulator in the formation of economically important traits in fruit trees. [MdDRB1] (Mus musculus) PubMed

 13355.

The proteolytic activation of HTRA relies on the C-terminus of the substrate allosterically binding to the PDZ1 domain, which triggers subsequent conformational change and oligomerization of the protein into 24-mers enabling proteolysis. [HTRA] (Mus musculus) PubMed

 13356.

structural features in Plasmodium falciparum purine nucleoside phosphorylase (PfPNP) that affect efficiency of catalysis (Mus musculus) PubMed

 13357.

The current results suggest a potential role for miR135 as an endogenous antidepressant (Mus musculus) PubMed

 13358.

The role of RpoN, a nitrogen limitation sigma factor, and its modulation protein YhbH, a novel ribosome-associated protein, in E. amylovora virulence, was investigated.[RpoN, YhbH] (Mus musculus) PubMed

 13359.

PTOX can act as a safety valve when the steady state is low while a certain amount of ROS is formed at high light intensities. (Mus musculus) PubMed

 13360.

Eic1 association with centromeres is entirely dependent on functional Mis18, but only partly dependent on functional Mis16RbAp46/48/Hat2 and Scm3HJURP.(Eic 1 protein and Eic2 protein) (Mus musculus) PubMed

 13361.

VvNPF3.2 is a low-affinity transporter for both nitrate and nitrite.[VvNPF3.2] (Mus musculus) PubMed

 13362.

AcrD from Erwinia amylovora is involved in resistance to a limited number of amphiphilic compounds, but in contrast to AcrD of E. coli, it is not involved in resistance to aminoglycosides.[ArcD] (Mus musculus) PubMed

 13363.

Study demonstrated that the extent of GlcNAcylation of Milton in mouse brain in vivo could vary-the increase in glucose availability upon feeding previously fasted mice increased the level of Milton O-GlcNAcylation. [Milton1, maybe the same as Trak1 protein] (Mus musculus) PubMed

 13364.

CHD5 is essential for CASZ1 function and the CHD5-CASZ1 interaction is necessary for cardiac morphogenesis [CHD5] (Mus musculus) PubMed

 13365.

The native Plasmodium falciparum uracil-DNA glycosylase was partially purified with a specific activity of 1,811.7 units/mg. The amino acid sequence showed only 24.8% similarity with the human enzyme.[uracil-DNA glycosylase] (Mus musculus) PubMed

 13366.

EscA is highly synchronized and critical to the process of escorting EspA to its final destination.[EscA] (Mus musculus) PubMed

 13367.

Results indicate that a single ribosomal protein gene retained by the kinetoplast mitochondrion serves as a possible functional link between editing and translation processes and provide the rationale for the evolutionary conservation of RPS12 pan-editing.[RPS12] (Mus musculus) PubMed

 13368.

MoPEX19 plays crucial roles in maintenance of peroxisomal and peroxisome-derived structures [PEX19] (Mus musculus) PubMed

 13369.

All parasites from both study areas contained the pfcrt 76 T allele. The pfmdr1 86Y allele was significantly more common in the parasites in the lower southern areas, while the pfmdr1 184F allele predominated in in the upper southern areas.[mdr1,crt] (Mus musculus) PubMed

 13370.

Authors conclude that the sagA/pel locus does not regulate emm expression in the M1T1 lineage.[sagA, emm] (Mus musculus) PubMed

 13371.

The ORFm164 epitope is presented already during the Immediate Early (IE) phase, based on the expression of an upstream mRNA starting within ORFm167 and encompassing ORFm164.[ORFm164] (Mus musculus) PubMed

 13372.

The in vivo protein expression profile shows maximal expression in trophozoites, and it exists in oligomeric form as trimer and hexamer. PfHSBP is predominantly localized in the parasite cytosol, but after heat shock it translocates to the nucleus.[hsbp] (Mus musculus) PubMed

 13373.

the avian ciliopathic mutant talpid2 causes craniofacial defects [talpid2] (Mus musculus) PubMed

 13374.

OS9 binding site in the classical swine fever virus Core protein was between Core residues (90)IAIM(93). [OS9] (Mus musculus) PubMed

 13375.

Tomato golden mosaic virus AL2 may act to sequester Arabidopsis CLM39 in the nucleus to prevent targeting of AL2 for degradation. [AL2] (Mus musculus) PubMed

 13376.

The Pfdhfr triple mutant was above 84% and close to fixation levels in all regions, whereas the Pfdhps double mutation ranged from 43.8 to 97% between the regions. The quintuple mutant (IRNGE) was the most prevalent in all regions.[dhfr,dhps] (Mus musculus) PubMed

 13377.

[HSP101] export across the Pparasitophorous vacuolar membrane requires heat shock protein 101 (HSP101), a ClpB-like AAA+ ATPase component of PTEX (Mus musculus) PubMed

 13378.

Authors conclude that diguanylate cyclase (VCA0965) is capable of c-di-GMP synthesis and that the first amino acid of the GG(D/E)EF motif is more tolerant of substitutions than currently appreciated.[diguanylate cyclase] (Mus musculus) PubMed

 13379.

These results confirm the involvement of GlxR on the expression of important carbon metabolic genes; adhA, ald, and ptsG.[GlxR] (Mus musculus) PubMed

 13380.

Not4 plays a role in protein quality control independently of the Ccr4 deadenylase.[Not4, ccr4] (Mus musculus) PubMed

 13381.

Plasmodium falciparum TCTP showed a lower B cell proliferative effect than human TCTP.[TCTP] (Mus musculus) PubMed

 13382.

pfcrt chloroquine resistance (CQR) allele seems to be fixed in the study area. Of the different haplotypes associated with CQR, only the CVIET genotype was identified. No reversal to the wild-type has occurred in Ethiopia.[crt] (Mus musculus) PubMed

 13383.

miR-203 regulates progenitor cell proliferation during adult zebrafish retina regeneration. [mir-203] (Mus musculus) PubMed

 13384.

findings establish RMD as a crucial component of the auxin-actin self-organizing regulatory loop from the nucleus to cytoplasm that controls rice cell growth and morphogenesis. (Mus musculus) PubMed

 13385.

These data infer that nonspecific DNA binding of the Imu3 immunity protein, prevents suicide of Escherichia coli producing the genotoxin Usp.[Imu3, Usp] (Mus musculus) PubMed

 13386.

These results suggested that CagA is not required for Helicobacter pylori-induced activation of NF-kappaB and upregulation of IL-8 expression in gastric epithelial cells. (Mus musculus) PubMed

 13387.

The small value of the heat capacity change of RRF unfolding appears to be the main stabilizing factor for RRF. [RRF] (Mus musculus) PubMed

 13388.

results indicate that Jam1a-Jam2a interactions facilitate the transduction of requisite Notch signals from the somite to the precursors of HSCs, and that these events occur well before formation of the dorsal aorta [Jam1a] (Mus musculus) PubMed

 13389.

X-ray structures of GluCl in apo states [GluCl alpha] (Mus musculus) PubMed

 13390.

The results indicated that SsnA is the first specific neutrophil extracellular trap evasion factor to be identified in Streptococcus suis.[SsnA] (Mus musculus) PubMed

 13391.

Perfrin is a 11.5 kDa C-terminal fragment of a 22.9 kDa protein and showed no sequence homology to any currently known bacteriocin. The 11.5 kDa fragment can be cloned into Escherichia coli, and expression yielded an active peptide.[perfrin] (Mus musculus) PubMed

 13392.

findings showed that MrgC immunoreactivity is distributed in both IB4-positive (non-peptidergic) and calcitonin gene-related peptide-positive (peptidergic) DRG neurons [MrgC] (Mus musculus) PubMed

 13393.

Data (including data from studies using RNA interference) suggest SEBOX is required for early embryonic development and gene expression regulation. [SEBOX homeobox protein; OG9 homeobox protein; skin- embryo- brain- and oocyte-specific homeobox] (Mus musculus) PubMed

 13394.

The JNK pathway plays an important role in mechanical ventilation-stimulated TNF-alpha expression in alveolar macrophages, but the injury-stimulated IL-8 expression may be regulated by other signaling pathways [JNK mitogen-activated protein kinase] (Mus musculus) PubMed

 13395.

The expression of glutathione peroxidase (GST-Px) and glutathione S-transferase P showed no statistically significant correlation with the analyzed variables.[GST-Px] (Mus musculus) PubMed

 13396.

Oriented solid-state NMR spectroscopy and biochemical cross-linking experiments were used to show that the ligand-free membrane protein transporter EmrE forms anti-parallel dimers with different monomer tilt angles relative to the lipid bilayer. [EmrE] (Mus musculus) PubMed

 13397.

Increased laminar flow protects endothelial barrier function via Sox18 dependent up-regulation of Claudin-5 expression.[Sox18] (Mus musculus) PubMed

 13398.

This work demonstrates that the cytosolic ABA receptor OsPYL/RCAR5 in O. sativa functions as a positive regulator of abiotic stress-responsive gene expression.[PYL5] (Mus musculus) PubMed

 13399.

AtSULT202B7 - displayed sulfating activity specific to flavonoids. (Mus musculus) PubMed

 13400.

MtNF-YA1 controls rhizobial infection progression by regulating the formation and the wall of infection threads.[MtNF-YA1] (Mus musculus) PubMed

 13401.

CorA is regulated by cytoplasmic Mg(2+) acting as a ligand and elucidate the basic conformational rearrangements responsible for Mg(2+)-dependent gating. [CorA] (Mus musculus) PubMed

 13402.

The rpoS allele containing and amber mutation, confer a moderate level of stress resistance and expression of RpoS-dependent genes in E. coli. (Mus musculus) PubMed

 13403.

These findings demonstrate that two hydroxypyruvate reductases encoded by OsHPR1 and OsHPR2 are involved in photorespiratory metabolism in rice.[OsHPR1 and OsHPR2] (Mus musculus) PubMed

 13404.

Atf1 can regulate ctt1(+) in both an Ecl1-dependent and an Ecl1-independent manner. [Atf1, Ecl1; Strain JY333] (Mus musculus) PubMed

 13405.

Results show that importin beta-4 facilitates AGO1 distribution to the nucleus, which is regulated by aae-miR-981 miRNA. The association of prohibitin with AGO1 may play an important role in its stability. [Ago1], [miR-981] and [importin beta4]. (Mus musculus) PubMed

 13406.

It has investigated the interaction between human L-FABP and the soluble domain of Plasmodium falciparum UIS3 by NMR spectroscopy.(UIS3 protein, Plasmodium) falciparum (Mus musculus) PubMed

 13407.

the wbuP gene of Escherichia coli O114 encodes a UDP-Gal: GlcNAc alpha-pyrophosphate-lipid beta-1,3-Gal-transferase that transfers the second sugar moiety in the assembly of the O114 repeating unit [WbuP] (Mus musculus) PubMed

 13408.

Using OmpT and OmpA as model proteins and Ficoll 70 as the crowding agent, here we investigated the effect of the macromolecular crowding condition on OMP membrane insertion. (Mus musculus) PubMed

 13409.

Analysis of the TbArl6 active site confirms that it lacks the key glutamine that activates the nucleophile during GTP hydrolysis in other small GTPases. (Mus musculus) PubMed

 13410.

Biochemical assays confirmed that bm2 mutants accumulate reduced levels of lignin with altered composition compared to wild-type. Hence, this study demonstrates a role for methylenetetrahydrofolate reductase (MTHFR) in lignin biosynthesis. [bm2] (Mus musculus) PubMed

 13411.

Cre-miR1174.2 is functional in Chlamydomonas and capable of triggering site-specific cleavage at the center (Mus musculus) PubMed

 13412.

The salt tolerance quantitative trait locus (QTL) involving HKT1;4 may be at least in part explained by functional variability among wheat HKT1;4-type transporters. [HKT1;4] (Mus musculus) PubMed

 13413.

Over-expression of OsACA6 confers tolerance to multiple stresses in transgenic plants, which correlated with reduced accumulation of reactive oxygen species in plants (OsACA6). (Mus musculus) PubMed

 13414.

It is apparent that monoubiquitination at Lys624 is opposed to phosphorylation at Ser7 in terms of regulating the catalytic activity of sorghum seed PEPC.[PEPC] (Mus musculus) PubMed

 13415.

(cysteine protease) PlasmoDJ1 is a putative cysteine protease motif of the DJ-1/PfpI superfamily, named for its potential to respond to stresses and for its role in parasite development. (Mus musculus) PubMed

 13416.

Over-expression of the MtSVP genes in Arabidopsis resulted in delayed flowering and flowers with many abnormal phenotypes such as leafy sepals, changes to floral organ number and longer pedicels than the wild type.[MtSVP1, MtSVP2] (Mus musculus) PubMed

 13417.

findings show PfDOC2 is a calcium lipid-binding protein of the protein kinase C type of DOC2 proteins [DOC2] (Mus musculus) PubMed

 13418.

the rate of ClpA catalyzed polypeptide translocation depends on [ATPgammaS] in the absence of ClpP, but not in the presence of ClpP. [ClpA] (Mus musculus) PubMed

 13419.

TgPHIL1 is necessary for a normal gliding motility and pathogenicity of Toxoplasma gondii. [TgPHIL1] (Mus musculus) PubMed

 13420.

The asymmetric structure of authentic RNA-filled cores of reverse transcriptase, determined to 14.5-A resolution.[reverse transcriptase] (Mus musculus) PubMed

 13421.

Results show that Vv-miR058 can play an important role by regulating the expression of Vv-PPO. (Mus musculus) PubMed

 13422.

CD2BP2 was significantly up-regulated in response to S. agalactiae.CD2BP2 plays an important role in the immune response to bacteria in Nile tilapia.[CDBP2] (Mus musculus) PubMed

 13423.

data suggested that SGL protein may be involved in regulating Gibberellin (GA) synthesis and response genes, that in turn, regulates grain length and plant height[SGL] (Mus musculus) PubMed

 13424.

The GPC-A1 and GPC-D1 genes have a redundant function and play a major role in the regulation of monocarpic senescence and nutrient remobilization in wheat. [GPC-A1, GPC-D1] (Mus musculus) PubMed

 13425.

OsDSR2 negatively regulated rice response to salt and simulated drought stresses as well as ABA signaling, which provided some useful data for understanding the functional roles of DUF966 family genes in abiotic stress responses in plants. [DSR2] (Mus musculus) PubMed

 13426.

Interaction among viral LAT, host PD-1, and CD11c CD8alpha(+) cells regulates herpes simplex virus 1 latency in mice. [LAT] (Mus musculus) PubMed

 13427.

GA2ox5, a gibberellin metabolism enzyme, is involved in plant growth, the root gravity response and salt stress. [GA2ox5] (Mus musculus) PubMed

 13428.

using X-ray-mediated hydroxyl radical labelling and mass spectrometry, demostration that Zn(II) binding triggers a highly localized, all-or-nothing change of water accessibility to the transport site and an adjacent hydrophobic gate [YiiP] (Mus musculus) PubMed

 13429.

Results show that the conserved acids were important to maintain the structure, thermostability, as well as the similarity of the enzymatic properties of those proteins. [Cel12B]. (Mus musculus) PubMed

 13430.

Bud23 enters the pre-40S pathway at the time of Ecm16 function.[Bud23, Ecm16] (Mus musculus) PubMed

 13431.

When the stored pathogen bacteria were cultured in liquid LB medium, they were able to regain activated, showing higher PthA expression level and enhanced pathogenicity, even though the activity was inferior (Mus musculus) PubMed

 13432.

The S-phase-promoting cyclin Clb5 activates Cdk1 to phosphorylate most, and perhaps all, of the 11 minimal cyclin-dependent kinase (CDK) phospho-consensus sites (S/T-P) in Sum1.[Sum1] (Mus musculus) PubMed

 13433.

The hyperactive form TdSOS1972 conferred a significant ionic stress tolerance to Arabidopsis plants. [TdSOS1] (Mus musculus) PubMed

 13434.

Meanwhile, the less accumulation of reactive oxygen species (ROS) and the greater antioxidant enzyme activity in sense plants implied the improved antioxidant competence by the overexpression of monoubiquitin gene Ta-Ub2 from wheat. [TaUB2] (Mus musculus) PubMed

 13435.

Expression of OsPAO1 appears to be quite low under physiological conditions, but is markedly induced in rice roots by spermine (Spm) or thermospermine treatment.[PAO1] (Mus musculus) PubMed

 13436.

MtEFD and cytokinin perception were shown as positive factors for bacterial wilt development.[MtEFD] (Mus musculus) PubMed

 13437.

The differential expression of miR-33b observed in crossbred gilts may in part account for differences in lipogenic gene expression and the fat:lean ratio between pig breeds. (Mus musculus) PubMed

 13438.

OmpA2 is required for normal stalk growth and that it plays a minor role in the stability of the outer membrane. [OmpA2] (Mus musculus) PubMed

 13439.

OsPT2 is involved in selenite uptake.[OsPT2] (Mus musculus) PubMed

 13440.

VvFLS2 differentially recognizes flg22 from different bacteria.[vvFLS2] (Mus musculus) PubMed

 13441.

OsSPX1 may be involved in cross-talks between oxidative stress, cold stress and phosphate homeostasis in rice seedling leaves [SPX1] (Mus musculus) PubMed

 13442.

du12(t) was mapped to an 840-kb region on the distal region of the long arm of chromosome 6. [du12(t)] (Mus musculus) PubMed

 13443.

ATM kinase (AtmA) controlled mitochondrial mass, function, and oxidative phosphorylation, which directly or indirectly influenced glucose uptake. (Mus musculus) PubMed

 13444.

Mutational analyses revealed that the MYND-domain of SMYD3 and domain III of hepatitis C virus NS5A are required for the interaction.[NS5A] (Mus musculus) PubMed

 13445.

These resutls showed that immunological cross-reactions between heat-stable toxin (ST) and the endogenous peptides can occur.[ST] (Mus musculus) PubMed

 13446.

We identified Ct875, a new Chlamydia trachomatis Slc1 client protein and T3S effector, which we renamed TepP (Translocated early phosphoprotein) (Mus musculus) PubMed

 13447.

These findings suggest that the electrostatic attractions of prM-E125, E-K93, and E-H246 residues are important to flavivirus virus-like-particle production.[prM, E] (Mus musculus) PubMed

 13448.

OmpW is the virus receptor for phage VP5 in the Vibrio cholerae O1 El Tor str. N16961. [OmpW] (Mus musculus) PubMed

 13449.

Removal of the carbohydrate-binding module alone could improve the thermostability of Man5XZ3, but further removal of the linker region resulted in worse thermostability.[Man5] (Mus musculus) PubMed

 13450.

Tec1 and Ste12 can associate with the transcriptional coregulators Msa1 and Msa2 (Msa1/2), which were previously found to associate with the cell cycle transcription factor complexes.[Tec1, Ste12, Msa1, Msa2] (Mus musculus) PubMed

 13451.

Medicago truncatula lysin motif receptor-like kinases, NFP and LYK3, produced in Nicotian induces defence-like responses [NFP][LYK3] (Mus musculus) PubMed

 13452.

In Sinorhizobium meliloti, sensing of N-acyl homoserine lactones with acyl chains composed of 14 or more carbons is facilitated by the outer membrane protein FadLSm.[FadLSm] (Mus musculus) PubMed

 13453.

Fatty acid kinase (Fak) is composed of two dissociable protein subunits encoded by separate genes.[FAK] (Mus musculus) PubMed

 13454.

TORC2-Ypk1 signaling negatively regulates the Ca(2+)/calmodulin-dependent phosphatase, calcineurin, to enable the activation of the amino acid-sensing eIF2alpha kinase, Gcn2, and to promote autophagy.[Ypk1] (Mus musculus) PubMed

 13455.

These results lead to a model in which CYT-19, and likely related DEAD-box proteins, rearranges complex RNA structures by preferentially interacting with and unwinding exposed RNA secondary structure.[CYT-19] (Mus musculus) PubMed

 13456.

These results suggest that Rab18 has an important role in viral assembly through the trafficking of the hepatitis C virus core protein to lipid droplets.[core protein] (Mus musculus) PubMed

 13457.

The role of p7 in the HCV life cycle is presently uncertain, but most of the research performed to date highlights its role in the virus assembly process.[p7] (Mus musculus) PubMed

 13458.

The X-ray crystal structure of epitope II on the E2 protein of hepatitis C virus, in complex with nonneutralizing antibody mAb#12, has been solved at 2.90-A resolution.[E2 protein] (Mus musculus) PubMed

 13459.

During infection, the RNA dependent RNA polymerase is governed between de novo RNA synthesis and back-priming by RNA sequence and environment, including a factor missing from the in vitro assay.[RNA dependent RNA polymerase] (Mus musculus) PubMed

 13460.

A null mutant of OsMet1-2, the major CG methylase in rice, was characterized.[OsMet1-2] (Mus musculus) PubMed

 13461.

study describes a second cytoplasmic Toxoplasma GCN2-like eIF2alpha kinase (TgIF2K-C) that is activated upon amino acid deprivation of intracellular tachyzoites; findings suggest GCN2-like kinases TgIF2K-C and TgIF2K-D evolved to have distinct roles in adapting to changes in the parasite's environment[IF2K-C] (Mus musculus) PubMed

 13462.

results provide the first evidence that FGF signaling regulates WNK4 function required for anterior formation in Xenopus development [wnk4] (Mus musculus) PubMed

 13463.

CnMT1 and CnMT2 polypeptides appear to be evolutionarily related to the small fungal metallothioneins (MT], responding to a highly selective pressure to chelate copper, and far from the properties of Zinc- and Cadmium-thioneins.[CnMT1, CnMT2] (Mus musculus) PubMed

 13464.

The relocation of cholera toxin B-subunit (CTB) in MucoRice-CTB-RNA interference may contribute to down-regulation of RAG2.[RAG2] (Mus musculus) PubMed

 13465.

FliO is required for the assembly or stability of other components of the export apparatus. [FliO; Helicobacter pylori B128] (Mus musculus) PubMed

 13466.

Cnm is a glycoprotein and that posttranslational modification mediated by PgfS contributes to the virulence-associated phenotypes linked to Cnm. [Cnm, PgfS] (Mus musculus) PubMed

 13467.

These results suggest that an NR-mediated early nitric oxide burst plays an important role in Aluminum resistance of wheat.[Nitrate reductase] (Mus musculus) PubMed

 13468.

The work provides insight for molecular understanding of RPP1 of P. falciparum and can be used for development of antimalarial drugs.[RPP1] (Mus musculus) PubMed

 13469.

miR-17-92 is not critically required for epidermal Langerhans cells homeostasis, maturation, antigen capture and migration.[miR-17-92] (Mus musculus) PubMed

 13470.

Genetic interaction analysis indicated that SPX3/5 are functional repressors of OsPHR2 (PHR2), the rice orthologue of the central regulator AtPHR1 for Pi homeostasis and Pi signalling. [SPX3, SPX5) (Mus musculus) PubMed

 13471.

The cahracterization of 2 galactosyltransferases, WbwCECO104 AND WbwCECO5 is reported.[WbwCECO104; WbwCECO5] (Mus musculus) PubMed

 13472.

The effects of alkali metals and pH on the activation of EvgS, part of the system that induces acid resistance, are reported.[EvgS] (Mus musculus) PubMed

 13473.

Investigated the contribution of each of the HAMP-like linker regions to the functionality of Nik1p and found that the HAMP4b linker was essential as its deletion resulted in the complete loss of activity. (Nik1, group III histidine kinase) (Mus musculus) PubMed

 13474.

S. aureus capsular polysaccharide (CP5) is linked to peptidoglycan in a manner requiring lcpABC genes [lcpA, lcpB and lcpC]. (Mus musculus) PubMed

 13475.

The structure and function of melibiose permease (MelB) are reported.[MelB] (Mus musculus) PubMed

 13476.

By integrating the data of GlnRs from Streptomyces coelicolor and Mycobacterium tuberculosis, we conclude that the actinomycete GlnR is atypical with respect to its unphosphorylated conserved Asp residue being involved in Arg/Asp/Thr interactions.[glnr] (Mus musculus) PubMed

 13477.

NPP1 exerts a negative effect on plant growth and starch accumulation in shoots, especially under high CO2 concentration and high temperature conditions (NPP1). (Mus musculus) PubMed

 13478.

Treating larvae with dsTcPDP1 induced pupae developmental arrestment, accompanied by accelerated fat body degradation. dsTcPDP1 treatments in adults resulted in reduced female fecundity.[PDP1] (Mus musculus) PubMed

 13479.

CH4 oxidation and N2 fixation were simultaneously activated in the root zone of wild-type rice in the low-nitrogen field and both processes are likely controlled by Ca(2+)/calmodulin-dependent protein kinase (encoded by CCaMK).[CCaMK] (Mus musculus) PubMed

 13480.

E. cloacae nitroreductase is not a good candidate for enzymatic production of aromatic amines.[oxygen insensitive nitroreductase] (Mus musculus) PubMed

 13481.

beta-xylosidase II may have a role in controlling the expression of the xynB1 and xynB2 genes in C. crescentus.[XynB2] (Mus musculus) PubMed

 13482.

Essential role of Tea4 in pathogencity in the absence of cell fusion is demonstarted. (Mus musculus) PubMed

 13483.

PHZA is under the control of the transcription factor Skn7 and is only involved in the control of the oxidative stress. (Mus musculus) PubMed

 13484.

The catalytic diversification of a GST isoenzyme from Phaseolus vulgaris (PvGST) which is induced under biotic stress treatment, was examined.[[PvGST] (Mus musculus) PubMed

 13485.

These results suggest a new model in which caveolin-1 might be involved in Salmonella entry via its interaction with SopE and Rac1, leading to enhanced membrane ruffling for phagocytosis into host cells.[SopE] (Mus musculus) PubMed

 13486.

The optimal temperature determined for NanJ or NanH enzymatic activity was 37 degrees C or 43 degrees C, respectively, while NanI activity increased until temperature reached 48 degrees C.[NanJ, NanH, NanI] (Mus musculus) PubMed

 13487.

These studies provide a complex picture of novel YqjI transcriptional regulation within the yqjH-yqjI intergenic region and suggest a possible model for communication between the YqjI binding sites at each target promoter.[YqjI] (Mus musculus) PubMed

 13488.

Reactive oxygen species sensing and signaling by TORC2/Ypk1 play a central physiological role in sphingolipid biosynthesis and in the maintenance of cell growth and viability.[Ypk1] (Mus musculus) PubMed

 13489.

new insights into LpoB-mediated regulation of peptidoglycan synthesis [LpoB] (Mus musculus) PubMed

 13490.

The critical condition for forming stable complexes of streptococcal enolase with canine plasminogen involves Str enolase binding to a surface.[Enolase] (Mus musculus) PubMed

 13491.

HC-Pro(K) loses the ability to interfere with microRNA pathways, although it retains a partial capability for RNA silencing suppression triggered by DICER-like ribonuclease (DCL). [HC-Pro(K)] (Mus musculus) PubMed

 13492.

Tomato ringspot virus (ToRSV) coat protein (CP) acts as an Argonaute (AGO)-hook protein and competes for AGO binding with a plant cellular GW/WG protein involved in translation repression. [CP] (Mus musculus) PubMed

 13493.

new insights into LpoB-mediated regulation of peptidoglycan synthesis [LpoB] (Mus musculus) PubMed

 13494.

OsCERK1 is indispensable for chitin perception and participates in innate immunity in rice, and also mediates the peptidoglycan response. [OsCERK1] (Mus musculus) PubMed

 13495.

lower to higher levels of transient expression of the poliovirus 2A protease strongly inhibited cellular Cap-dependent translation.[2A protease] (Mus musculus) PubMed

 13496.

Our results suggest that OsMY1 is an important target of OsRac5 and that these two genes are involved in the same biological processes in rice growth and development. (Mus musculus) PubMed

 13497.

the identification of RNase II as a parasite protein controlling the expression of virulence genes involved in pathogenesis in patients with severe malaria may provide new strategies for reducing malaria mortality [RNase II] (Mus musculus) PubMed

 13498.

Ghd7 functions to integrate the dynamic environmental inputs with phase transition, architecture regulation, and stress response to maximize the reproductive success of the rice plant.[Ghd7] (Mus musculus) PubMed

 13499.

Miz1 is important not only for survival of neural crest precursors, but also for maintenance of integrity of the neural folds and tube, via correct formation of the apical adhesion complex therein. [miz1] (Mus musculus) PubMed

 13500.

This study reveals a possible association between VacA-induced apoptosis in gastric epithelial cells, and activation of endoplasmic reticulum stress in H. pylori-positive gastric mucosa.[VacA] (Mus musculus) PubMed

 13501.

C4 is a novel cellular substrate of the HCV NS3/4A protease.[NS3/NS4A] (Mus musculus) PubMed

 13502.

The role of Rbt1 in the interaction of C. albicans with biotic and abiotic surfaces independently of its morphological state, was investigated.[Rbt1] (Mus musculus) PubMed

 13503.

The concerted negative regulation of BAF60a and BAF60b by the muscle-specific microRNAs (myomiRs) miR-133 and miR-1/206 during somite differentiation, is reported.[miR133] (Mus musculus) PubMed

 13504.

A novel gene, Sdgc (sex chromosome-dependent differential expression in germ cells), whose transcripts are highly enriched in early XY germ cells, was identified.[Sdgc] (Mus musculus) PubMed

 13505.

a role for YfgM in mediating the trafficking of proteins from the Sec translocon to the periplasmic chaperone network that contains SurA, Skp, DegP, PpiD, and FkpA [YfgM] (Mus musculus) PubMed

 13506.

structure and activities of undecaprenyl pyrophosphate phosphatase [UppS] (Mus musculus) PubMed

 13507.

both HlyA and LtxA trigger acute release of ATP from human erythrocytes that preceded and were not caused by cell lysis [HlyA] (Mus musculus) PubMed

 13508.

the central region of SecM is not just a geometric linker but it participates actively in the regulation of translation arrest [secM] (Mus musculus) PubMed

 13509.

Pregnancy-specific glycoprotein 1 (PSG1) activates TGF-beta and prevents dextran sodium sulfate (DSS)-induced colitis in mice. (Mus musculus) PubMed

 13510.

These results strongly suggest that miR156 is a phloem-mobile signal regulating potato development.[Microrna156] (Mus musculus) PubMed

 13511.

These data indicate that IL-35 effectively protects the myocardium from the pathogenesis of CVB3-induced viral myocarditis, which may be attributable to reduced Th17 production.[IL-35] (Mus musculus) PubMed

 13512.

SSG4 is a novel protein that influences the size of starch grains.[SSG4] (Mus musculus) PubMed

 13513.

The putative OsKS2 gene was a chromosome 4-located ent-kaurene synthase (KS), encoding the enzyme that catalyses an early step of the GA biosynthesis pathway. [OsKS2] (Mus musculus) PubMed

 13514.

H.pylori NhaA only has a small acidic shift of its pH-dependent activity profile compared to the other transporters [NhaA] (Mus musculus) PubMed

 13515.

palmitoylation-dependent membrane localization of Pit is required for the interaction with and the activation of OsRac1 [Rac1][Pit] (Mus musculus) PubMed

 13516.

flagellin glycosylation reduces recognition of flagellin by host TLR5, providing an evasive strategy to infecting bacteria [fliC] (Mus musculus) PubMed

 13517.

the function and evolution of expansin genes [expansin] (Mus musculus) PubMed

 13518.

intramolecular electron transfer rates between the copper centers of the small laccase from Streptomyces coelicolor at room temperature and pH 7.4 [MCO] (Mus musculus) PubMed

 13519.

sHIP is a novel virulence factor forming tetrameric organization composed of four helix-loop-helix motifs.[sHIP] (Mus musculus) PubMed

 13520.

One function of Bug22 is to regulate the anchoring of the beak-like structures to the doublet microtubules and confine flagellar beating to a plane.[Bug22] (Mus musculus) PubMed

 13521.

PPARbetais the first identified transcription factor that interprets an epigenetic signature of pluripotency during embryonic development [PPAR beta] (Mus musculus) PubMed

 13522.

The salinity-responsive bread wheat gene TaAOC1 enhanced level of tolerance to salinity.[TaAOC1] (Mus musculus) PubMed

 13523.

the complex formed by HCV E1E2, ApoB, and ApoE may initiate lipoviral particle morphogenesis [E1][E2] (Mus musculus) PubMed

 13524.

cj0268c gene is involved in mediating C. jejuni induced immunopathogenesis in vivo [cj0268c] (Mus musculus) PubMed

 13525.

The double zinc finger domain and adjacent accessory domain of loz1 are necessary for DNA binding and zinc sensing. [loz1] (Mus musculus) PubMed

 13526.

Through proteomic, biochemical, and genetic analyses, results show that Nts1, together with Mug165 and Png3, defines a novel complex containing the evolutionarily conserved Clr6 histone deacetylase. [NTS1 and Png3]. (Mus musculus) PubMed

 13527.

Both AcrB beta-hairpins and AcrA act to stabilize the tripartite complex and induce TolC opening for drug expulsion.[AcrA, AcrB, TolC] (Mus musculus) PubMed

 13528.

pH-dependent activation of Streptomyces hygroscopicus transglutaminase mediated by intein.[transglutaminase] (Mus musculus) PubMed

 13529.

WLIM1a has dual roles in cotton fiber development, elongation, and secondary wall formation.[WLIM1a] (Mus musculus) PubMed

 13530.

a major role for ptac2, ptac10, ptac12, murE, and prin2 in the expression of plastid tRNAs [ptac2], [ptac10], [ptac12], [murE], [prin2] (Mus musculus) PubMed

 13531.

Alba components such as OsAlba1, especially from a plant where there is no evidence for a major chromosomal role, might play important function in stress adaptation [Alba1] (Mus musculus) PubMed

 13532.

promoter binding by the RNA replicase has implications for the regulatory mechanisms involved in the transcription of viral genes and replication of the viral RNA genome (RNA replicase) (Mus musculus) PubMed

 13533.

Important role of GSNOR during normal plant development and in plant responses to several types of abiotic stress conditions.[GSNOR] (Mus musculus) PubMed

 13534.

TMBr-3 and TM5NM1 modestly affected actin assembly kinetics, in an opposite manner.[TmBr-3] (Mus musculus) PubMed

 13535.

Expression of proteins of interest via Lip2p fusion provides a convenient expression and purification scheme as well as enables monitoring the accumulation of secreted fusion proteins in the medium through the intrinsic lipase activity of the fusion. (Mus musculus) PubMed

 13536.

OsJAR1 is the most important jasmonic acid -isoleucine conjugating enzyme in the wounding response during the vegetative stage.[OsJAR1] (Mus musculus) PubMed

 13537.

The structure of HtsA identifies a novel form of ligand entrapment composed of many positively charged residues. Through ionic interactions, the binding pocket appears highly adapted for the binding of highly anionic siderophore staphyloferrin A. (HtsA) (Mus musculus) PubMed

 13538.

These results suggested that Rta represses IRF-3 expression by increasing E2F1 binding to the IRF-3 promoter.[Rta] (Mus musculus) PubMed

 13539.

The present study revealed that the residues that form the important motifs of hepatitis c virus NS5B remain conserved.[NS5B] (Mus musculus) PubMed

 13540.

Important role of GSNOR during normal plant development and in plant responses to several types of abiotic stress conditions.[GSNOR] (Mus musculus) PubMed

 13541.

strain SS1 - role in colonization and stomach metaplasia [VacA] (Mus musculus) PubMed

 13542.

PIP2;4 and PIP2;7 are involved in mediating boron transport in rice and provide tolerance via efflux of excess boron from roots and shoot tissues.[PIP2;4] [PIP2;7] (Mus musculus) PubMed

 13543.

Authors named Debaryomyces fabryi AY347871.2 and Debaryomyces hansenii DEHA2C11374p as XYLH from Xylose/H(+) symport.[XYLH] (Mus musculus) PubMed

 13544.

this article presents the x-ray structure of staphylococcal enterotoxin B in complex with its receptors, the TCR and MHC class II, forming a ternary complex. [SEB] (Mus musculus) PubMed

 13545.

HCV NS5A associates with phosphorylated eIF4E and 40S ribosomes to form a complex that appears to regulate HCV IRES translation. [NS5A] (Mus musculus) PubMed

 13546.

Drug resistance phenotype is caused by a 4.1 kb deletion in the 5' upstream region of the pfmrp2 gene that leads to an alteration in the pfmrp2 transcription and thus increased level of PfMRP2 protein.[PfMRP2] (Mus musculus) PubMed

 13547.

investigate NleC substrate specificity, showing that four residues around the cleavage site in the DNA-binding loop of the NF-kappaB subunit RelA strongly influence the cleavage rate (NleC) (Mus musculus) PubMed

 13548.

Overall, these studies indicate FlgC is a major factor in the binding ability of Salmonella to the intestinal mucosa of poultry.[FlgC] (Mus musculus) PubMed

 13549.

The crystal structure of the Hermes transposase-DNA complex reveals that Hermes forms an octameric ring organized as a tetramer of dimers. (Mus musculus) PubMed

 13550.

JMJ705 is a biotic stress-responsive trimethylated histone H3 lysine 27 demethylase that may remove trimethylated histone H3 lysine 27 from marked defense-related genes and increase their basal and induced expression during pathogen infection.[JMJ705] (Mus musculus) PubMed

 13551.

Ustilago glucosidase I (Gls1) and glucosidase II beta-subunit (Gas2), are essential for its pathogenic interaction with maize. [Gls1] (Mus musculus) PubMed

 13552.

data suggest that CYP96B4 may be an important regulator of plant growth that affects plant height in rice[CYP96B4] (Mus musculus) PubMed

 13553.

The catalytic triad of GtgE, an effector protein that modulates trafficking of the Salmonella-containing vacuole, has been resolved. [GtgE] (Mus musculus) PubMed

 13554.

The Pim1p activity declines in aging cells and that Pim1p deficiency shortens the replicative life span of yeast mother cells. (PIM1 protein, S cerevisiae) (Mus musculus) PubMed

 13555.

The downregulated expression of the ZmPYL3 gene and the upregulated expression of the ZmPP2C16 gene are responsive to the induction of exogenous Abscisic acid.[PP2C16] (Mus musculus) PubMed

 13556.

The crystal structure of a tryptophan-substituted double mutant of Hcp1 from enteroaggregative Escherichia coli.[Hcp1] (Mus musculus) PubMed

 13557.

Tsr-HAMP deletion derivatives were constructed and their steady-state signal outputs and sensory adaptation properties with flagellar rotation and receptor methylation assays, were characterized.[Tsr] (Mus musculus) PubMed

 13558.

Dissociation of the AcrB trimer drastically decreased its interaction with AcrA.[AcrB] (Mus musculus) PubMed

 13559.

KlHxk1 is likely to have a repressive function in a multitude of metabolic pathways.[KlHxk1] (Mus musculus) PubMed

 13560.

Results show that Xyl10g can attack highly substituted, unsubstituted, and low-substituted xylans suggesting a role in lignocellulose degradation. [Xyl10g]. (Mus musculus) PubMed

 13561.

[lnu(E)] - novel lincosamide resistance gene (Mus musculus) PubMed

 13562.

Sgf29 and Gcn5 perform distinct functions at native telomere boundary regions on the chromosome.[Sgf29] (Mus musculus) PubMed

 13563.

[CCG-8] - positively regulates the ketoconazole responses of many genes and is required for wild-type resistance to antifungal azoles (Mus musculus) PubMed

 13564.

Purified VgrG1 of E. coli O157 and c3393 of E. coli CFT073 form trimer in solution and are rich in beta-structure.[VgrG] (Mus musculus) PubMed

 13565.

OBAP1 protein is involved in the stability of oil bodies.[OBAP1] (Mus musculus) PubMed

 13566.

The 5-HT7-type receptor encoding cDNA shows considerable sequence similarity with cognate 5-HT7 receptors. PCR demonstrated high expression levels in the brain. Trica5-HT7 was dose-dependently activated by 5-HT.[5-HT7] (Mus musculus) PubMed

 13567.

Kinase activity and N-terminal phosphorylation sites of Rad53 were crucial for its function in the resistance to genotoxic stress, maintenance of heterozygosity, cell cycle regulation and polarized growth.[Rad53] (Mus musculus) PubMed

 13568.

The catalytic region of the Trypanosoma cruzi vacuolar transporter chaperone 4 (VTC4) is a polyphosphate kinase.[VTC4] (Mus musculus) PubMed

 13569.

Targeted disruption of PpCMT results in an approximately 50% reduction in global cytosine methylation levels. PpCMT and PpLHP1 interact through their chromo domains, while PpLHP1 homodimerizes through its chromo shadow domain. [PpCMT, PpLHP1] (Mus musculus) PubMed

 13570.

Results show that SKa is a pleiotropic enzyme with vital roles throughout the life cycle of Leishmania. [ska]. (Mus musculus) PubMed

 13571.

In addition to its role in peroxide sensing and response, Srx1 was also found to be required for a peroxiredoxin-independent function in promoting fungicide-dependent cell swelling and growth arrest. [srx1] (Mus musculus) PubMed

 13572.

RBR-2 did not play a comparable role in the maintenance of quiescent germ cells in dauer larvae, implying that it represses stress that occurs as a consequence of germ cell proliferation, rather than stress that accumulates in nondividing cells.[RBR-2] (Mus musculus) PubMed

 13573.

Authors showed that zrfC is essential for virulence in the absence of zrfA and zrfB, which contribute to fungal pathogenesis to a lesser extent than zrfC and are dispensable for virulence in the presence of zrfC.[zrfC] (Mus musculus) PubMed

 13574.

The reduced ability of the mdtABC- and mdtUVW-deficient mutants to multiply in apple rootstock suggests that the efflux pumps are involved in resistance to plant antimicrobials.[mdtABC, mdtUVW] (Mus musculus) PubMed

 13575.

OsNAC111 positively regulates the expression of a specific set of pathogenesis-related (PR) genes in the disease response and contributes to disease resistance. [OsNAC111] (Mus musculus) PubMed

 13576.

The study indicates Alanyl-tRNA synthetase unfolding does not follow the hierarchical model as in this enzyme tertiary structure gets disrupted well before the disruption of quaternary interaction. [Alanyl-tRNA synthetase] (Mus musculus) PubMed

 13577.

In vivo analyses using beta-galactosidase fusions indicate that LeuO activates hilE transcription.[hilE] (Mus musculus) PubMed

 13578.

These data establish that host switch requires high levels of translationally silent UIS4 RNA, which permits stage conversion, yet avoids premature expression of this liver stage-specific protein.[UIS4] (Mus musculus) PubMed

 13579.

OsAMT1;1 enhanced overall plant growth, especially under suboptimal NH4(+) levels. [OsAMT1;1] (Mus musculus) PubMed

 13580.

The plant homeodomain motif of OsTrx1 binds to native histone H3 from the calf thymus and that OsTrx1 binds to Ehd3 through the region between the plant homeodomain and SET domains.[Trx1, Ehd3] (Mus musculus) PubMed

 13581.

The whole transcriptome analysis confirmed the central role of salicylic acid (SA) in orchestrating Ny-1-mediated responses and showed that the absence of SA leads to significant changes at the transcriptome level. [Ny-1] (Mus musculus) PubMed

 13582.

Two major loci, BrSIO1 and BrSIO2, work additively in overcoming Self-incompatibility (SI) during CO2 treatment. [BrSIO1, BrSIO2] (Mus musculus) PubMed

 13583.

Results show that the protein encoded by the wbtj gene from F. tularensis is an N-formyltransferase that functions on dTDP-4-amino-4,6-dideoxy-d-glucose as its substrate. (Mus musculus) PubMed

 13584.

Invasive medaka melanomas show increased levels of sdf1, cxcr4, and cxcr7 gene expression.[Sdf1, Cxcr7, Xmrk] (Mus musculus) PubMed

 13585.

These data suggest that CDPK7 is crucial for proper maintenance of centrosome integrity required for the initiation of endodyogeny. (Mus musculus) PubMed

 13586.

CsSUS3 participated in resisting hypoxic stress.[CsSUS3] (Mus musculus) PubMed

 13587.

results show that the prokaryotic homolog of Rubisco Accumulation Factor 1 (RAF1) from Thermosynechococcus elongatus is expressed in cyanobacterial cells and interacts with a large Rubisco subunit (RbcL)[RAF1] (Mus musculus) PubMed

 13588.

study reports expression of gene coding for a putative GH30 xylanase protein,isolation and purification of the corresponding protein and characterization of catalytic properties; found the gene codes for a novel GH30 xylanase designated XYN VI with catalytic properties almost identical to bacterial GH30 xylanases [XYN VI] (Mus musculus) PubMed

 13589.

Using RNA affinity chromatography with a 300 nt regulatory region within the amastin 3' UTR as bait, authors identified an Alba-domain protein of 25 kDa (LiAlba20) as a specific amastin mRNA-binding partner.[Aba20] (Mus musculus) PubMed

 13590.

NPB may participate in the regulation of feeding and gene expression of pituitary growth hormone and prolactin in Nile tilapia.[NPB] (Mus musculus) PubMed

 13591.

Arabino-1, 4-lactone oxidase (ALO) deletion mutants showed reduced survival in mouse macrophages and are impaired in their infectivity in vivo.[ALO] (Mus musculus) PubMed

 13592.

Our novel findings define m154 as an important player in murine cytomegalovirus innate immune regulation (Mus musculus) PubMed

 13593.

crystal structure of Streptococcus pyogenes Cas9 in complex with a single-molecule guide RNA and a target DNA containing a canonical 5'-NGG-3' protospacer adjacent motif (PAM) (Mus musculus) PubMed

 13594.

findings show GHIP, a novel pneumococcal virulence factor, appeared to play a critical role in bacterial survival and the induction of host innate immune response during pneumococcal infection [GHIP] (Mus musculus) PubMed

 13595.

The data reveals that the loosely formed capsid structure is reinforced post-assembly by gpD in bacteriophage lambda (gpD). (Mus musculus) PubMed

 13596.

TbAAT6-RNAi lines of both bloodstream and procyclic form trypanosomes showed reduced susceptibility to eflornithine, whereas the sensitivity to acivicin remained unchanged, indicating that acivicin enters the cell by more than one transporter. (Mus musculus) PubMed

 13597.

Apoptosis may play different roles in the early and late infective stages of Phytophthora sojae, and that PsTatD4 is a key regulator of infection. [PsTatD4] (Mus musculus) PubMed

 13598.

The pbp1a mutant showed much greater sensitivity to lysozyme than either single mutant or the wild-type strain, suggesting that these mutations reduced cell wall resistance to protein secretion.(PBP1a protein) (Mus musculus) PubMed

 13599.

these data indicate that inactivation of either acs-3 or nhr-25 causes stress sensitivity and increased expression of innate immunity/stress genes, most likely by different mechanisms. (Mus musculus) PubMed

 13600.

VirB1-89K facilitates the assembly of 89K type IV secretion system apparatus by catalyzing the degradation of the peptidoglycan cell wall, thus contributing to the pathogenesis of Streptococcus suis 2 infection.[VirB1] (Mus musculus) PubMed

 13601.

This work identifies new pathways directly controlled by AdpA and that are involved in Streptomyces lividans development and primary or secondary metabolism.[AdpA] (Mus musculus) PubMed

 13602.

Bel1 fragment with residues 215-223, which bears the NLS, interacts with KPNA1, KPNA6, and KPNA7. [Bel1] (Mus musculus) PubMed

 13603.

Data indicate that filaments consisting of either flagellins FlaA or FlaB are equally supportive for flagella surface adhesion: [Fla and FlaB] (Mus musculus) PubMed

 13604.

TaPIE1 positively regulates the defense responses to Rhizoctonia cerealis and freezing stresses.[TaPIE1] (Mus musculus) PubMed

 13605.

Authors present a model for the interaction of nucleotide-binding and leucine-rich repeat domain proteins in plants: RGA4 mediates cell death activation, while RGA5 acts as a repressor of RGA4 and as an avirulence receptor.[RGA4, RGA5] (Mus musculus) PubMed

 13606.

These data demonstrate a role for FRE3 in the virulence of Cryptococcus neoformans.[FRE3] (Mus musculus) PubMed

 13607.

we provide a detailed analysis of RON5 to resolve outstanding questions about complex organization, assembly and function during invasion. (Mus musculus) PubMed

 13608.

Together, these results suggest that the E3 ligase LsRZF1 is an important regulator of water deficit stress during early seedling development. [LsRZF1] (Mus musculus) PubMed

 13609.

These results identify egr-1 as part of a longevity-promoting circuit that changes with age in a manner that is beneficial for the lifespan of the organism.[Egr-1] (Mus musculus) PubMed

 13610.

Cyp18 may play a crucial role in macrophage migration, and in assisting with transport of Toxoplasma gondii via CCR5-independent mechanisms.[Cyp18] (Mus musculus) PubMed

 13611.

The characterization of SbHKT1;4, a member of the HKT gene family from Sorghum bicolor, is reported.[SbHKT1;4] (Mus musculus) PubMed

 13612.

All these results together show that, at least under the tested conditions, RpoS is the central regulator in the hlyE regulatory network, integrating multiple environmental signals and global regulators.[RpoS, hlyE] (Mus musculus) PubMed

 13613.

AtlL is involved in cell separation, stress-induced autolysis and contributes to bacterial pathogenesis. [AtlL] (Mus musculus) PubMed

 13614.

Both the ISA1 homomultimer and ISA1/ISA2 heteromultimer function in the maize leaf.[ISA1, ISA2] (Mus musculus) PubMed

 13615.

Allelic mutations of CYP90D2/D2 confer varying degrees of dwarfism and leaf angle, thus providing useful information for molecular breeding in grain crop plants.[CYP90D2/D2] (Mus musculus) PubMed

 13616.

transgenic F2 crop-weed hybrids produced 48-125% more seeds per plant than nontransgenic controls in monoculture- and mixed-planting designs without glyphosate application. [5-enolpyruvoylshikimate-3-phosphate (EPSP) synthase transgene] (Mus musculus) PubMed

 13617.

results indicate involvement of galU in the virulence factor production and pathogenicity in X. campestris pv. campestris, and a role for galU in stress tolerance of this crucifer pathogen [GalU] (Mus musculus) PubMed

 13618.

Disruption of BRI1 has pleiotropic effects on disease resistance in addition to affecting plant development. (Mus musculus) PubMed

 13619.

Plasmodium falciparum calcineurin thus serves as an effector of Ca(2+)-dependent AMA-1 microneme protein exocytosis by regulating depolymerization of apical actin.[calcineurin, actin] (Mus musculus) PubMed

 13620.

The target of tae-miR164, a novel NAC transcription factor from the NAM subfamily of wheat, plays an important role in regulating the resistance of host plants to stripe rust.[tae-miR164, NAC21/22] (Mus musculus) PubMed

 13621.

Staphylococcus aureus replicated intracellularly only in presence of a functional PSMalpha operon thereby illustrating that bacteria grow in the host cell cytoplasm upon phagosomal escape.[PSMalpha] (Mus musculus) PubMed

 13622.

The effects of exogenous urocortin-3 and corticotrophin-releasing hormone on the ghrelin to growth hormone secretagogue receptor 1a (GHS-R1a) system is reported.[GHS-R1a] (Mus musculus) PubMed

 13623.

Authors find that this process is markedly enhanced by the murine cytomegalovirus (MCMV)-encoded CC chemokine, MCK2, which promotes recruitment of CX3CR1(hi) patrolling monocytes to initial infection sites in the mouse. (Mus musculus) PubMed

 13624.

These results indicate a critical role for MCAF1 in AP-1-dependent Rta activation of BZLF1 transcription.[Rta] (Mus musculus) PubMed

 13625.

VP11 is also the first reported White spot syndrome virus structural protein to interact with the major nucleocapsid protein VP664.[VP11] (Mus musculus) PubMed

 13626.

PTOX1 is required for both carotenoid and strigolactone (SL) synthesis resulting in SL-deficient phenotypes in rice.[PTOX1] (Mus musculus) PubMed

 13627.

The function and evolution of OsMADS34 were studied. [OxMADS34] (Mus musculus) PubMed

 13628.

The correlation between HIV-1 gp120 V4 region polymorphism and the function of the region on virus entry, was examined.[gp120] (Mus musculus) PubMed

 13629.

These results suggest that hha regulates motility of EHEC O157:H7 directly as well as indirectly by controlling the transcription of qseBC.[Hha, QseB, QseC] (Mus musculus) PubMed

 13630.

In conclusion, we demonstrate that in M. truncatula LOG proteins might be implicated in nodule primordium development and lateral root formation. [MtLOG1 and MtLOG2] (Mus musculus) PubMed

 13631.

Adaptor protein MecA in Streptococcus mutans plays a crucial role in recognizing and targeting SigX for degradation by the protease ClpC/ClpP.[SigX] (Mus musculus) PubMed

 13632.

The Cph-like expression level was downregulated by exogenous 20-hydroxyecdysone or starvation. [Cph-like] (Mus musculus) PubMed

 13633.

These results suggest that an antipain-sensitive protease or cathepsin L (or a related protease) is a candidate for pp25 degradation. [pp25] (Mus musculus) PubMed

 13634.

Data indicate that the specific binding activity of factor H-binding protein (Fhb) with human serum IgG (hIgG) was identified and located on the factor H-binding protein Fhb-N(45-344aa): [Fhb] (Mus musculus) PubMed

 13635.

data give new insights into the assembly of the poxvirus DNA polymerase cofactor and may be useful for the design and rational improvement of antivirals targeting the D4/A20 interface [D4/A20] (Mus musculus) PubMed

 13636.

role of TteCspC in cold shock response in Thermoanaerobacter tengcongensis [eCspC] (Mus musculus) PubMed

 13637.

The amphioxus GnRH-like peptide, with its distinct primary structure, activated a receptor with equal potency to multiple ligands that span the GnRH superfamily. [GnRH-like peptide] (Mus musculus) PubMed

 13638.

Results demonstrate that Lon inactivation of SulA in vivo requires binding to the N domain and ATP hydrolysis. Therefore, Lon can function as a protease or a chaperone. [lon] [SulA]. (Mus musculus) PubMed

 13639.

Helicobacter pylori vacA increase markedly gastric mucosal TGF-beta1 mRNA expression in gastritis patients. [vacA] (Mus musculus) PubMed

 13640.

The Deltasao mutant did not present significant differences on levels of adhesion/invasion of swine respiratory epithelial cells compared to wild type. [Sao] (Mus musculus) PubMed

 13641.

Therefore, while Agr regulates fibronectin binding in small-colony variants, it cannot promote hemolysin production in the absence of a functional electron transport chain.[Agr] (Mus musculus) PubMed

 13642.

Overall, the results suggest that TgSPATR contributes to invasion and virulence, findings that have implications for the many genera and life stages of apicomplexans that express SPATR.[SPATR] (Mus musculus) PubMed

 13643.

Authors conclude that teg49, embedded within the extended promoter regions of sarA, is modulated by sigB and cshA and plays an important trans-acting role in modulating the transcription and ensuing expression of sarA.[teg49, SarA] (Mus musculus) PubMed

 13644.

Results show naturally resistance-associated variants in 14% of the HCV strains. T54S was the most common mutation (4%) detected. (Mus musculus) PubMed

 13645.

ZmHsp17.0-CII and ZmHsp17.8-CII oligomerize to form dodecamers at temperatures below heat shock. During heat shock, the latter dissociates into smaller oligomers than the former, and is a more efficient chaperone with citrate synthase.[hsp17.0,hsp17.8] (Mus musculus) PubMed

 13646.

Authors found that mutants lacking GPX31-33 were more susceptible to killing by phagocytic cells, suggesting that glutathione peroxidases are required for full resistance to innate immune effector cells.[GPX31, GPX32, GPX33] (Mus musculus) PubMed

 13647.

SmMAK16 from Schistosoma mansoni localizes to the nucleolus using three separate signals, two nuclear localization signals and one nucleolar localization signal.[MAK16] (Mus musculus) PubMed

 13648.

Overall, the results show the viability of AAV gene transfer of arginine kinase gene to skeletal muscle, and provide support of PArg as a reporter that can be used to non-invasively monitor the transduction of genes for therapeutic interventions. (Mus musculus) PubMed

 13649.

MicroRNA125b suppresses the proliferation and osteogenic differentiation of human bone marrowderived mesenchymal stem cells. (Mus musculus) PubMed

 13650.

DNF2, a Medicago truncatula gene has been described as required for nitrogen fixation, bacteroid's persistence and to prevent defense-like reactions in the nodules [DNF2] (Mus musculus) PubMed

 13651.

Collectively, these data suggest that cepA is a novel multidrug resistance gene and probably functions in the efflux of toxic substances from the inside of cells to the environment, thus allowing cells to reach a higher cell yield.[cepA] (Mus musculus) PubMed

 13652.

The high-temperature adult-plant resistance gene in PI 178759 is different from the previously reported Yr39, Yr52, YrZH84, and YrC591, also located on chromosome 7BL, and is therefore designated as Yr59.[Yr59] (Mus musculus) PubMed

 13653.

Reports show that holin S105 triggering is correlated with the formation of micron-scale membrane holes. Early triggering formed approximately the same number of holes but smaller[S105] (Mus musculus) PubMed

 13654.

The Sr45 region was fine mapped in a large mapping population generated by crossing CS1D5406 (disomic substitution line with chromosome 1D of RL5406 substituted for Chinese Spring 1D) with Chinese Spring.[Sr45] (Mus musculus) PubMed

 13655.

These data describe the FMRFamide gene in A. gambiae, and show that FMRFamide-like peptides are complex modulators of mosquito circulatory physiology.[FMRFamide] (Mus musculus) PubMed

 13656.

proline transporter (TcAAAP069)overexpressing parasites have an increased intracellular proline concentration leading to improved resistance to trypanocidal drugs and also to reactive oxygen species. (TcAAAP069) (Mus musculus) PubMed

 13657.

Knockout of LmSNF1 prevents L. maculans from properly derepressing the production of cell wall degrading enzymes, compromises the utilization of certain carbon sources, and impairs fungal pathogenicity on canola.[LmSNF1] (Mus musculus) PubMed

 13658.

Analysis of alanine-scanning mutants showed that M116A and G120A had a similar localization to wild type pc4, being localized at PD and chloroplasts, but all other mutants were only localized at chloroplasts and not at PD.[pc4] (Mus musculus) PubMed

 13659.

REsults show that coexpression of P450 reductase with Sam5 in E. coli enhanced hydroxylation by approximately from 34 to 50%, depending on the flavonoid used. [OsPR] (Mus musculus) PubMed

 13660.

FLO6 may act as a starch-binding protein involved in starch synthesis and compound granule formation through a direct interaction with ISA1 in developing rice seeds. [FLO6] (Mus musculus) PubMed

 13661.

Furthermore, the role of ORF4 in cell apoptosis and a possible interaction with the ORF1 associated Rep protein could perhaps explain the rapid viral growth in the early stage of infection.[ORF4] (Mus musculus) PubMed

 13662.

Lr67/Yr46 confers partial resistance to stem rust and powdery mildew and is associated with leaf tip necrosis.[Lr67/yr46] (Mus musculus) PubMed

 13663.

miR-NID1 represses NRXN1 expression by binding to TDP-43. [new entry] (Mus musculus) PubMed

 13664.

backbone dynamics information for HP1043 (HP-RR0 implies that structural flexibilities in HP-RR(r) are necessary for the phosphorylation site and the dynamic nature of HP-RR(e) is essential for the regulation of interaction between protein and DNA. (Mus musculus) PubMed

 13665.

The oxygen-independent reducing properties of Lactococcus lactis contribute to Staphylococcus aureus agr downregulation.[agr] (Mus musculus) PubMed

 13666.

silkworm Piwi proteins function as a chromatin regulator in collaboration with HP1a and HP1b.[HP1a, HP1b] (Mus musculus) PubMed

 13667.

The charged residues are involved in electrostatic interactions driving Crl-sigmaS complex formation. [Crl, RpoS] (Mus musculus) PubMed

 13668.

However, optimal growth and zinc accumulation in vitro and pneumococcal survival and proliferation in vivo required production of all four Pht proteins, PhtABDE.[PhtA, PhtB, PhtD, PhtE] (Mus musculus) PubMed

 13669.

The expression level of tdh at different temperatures ranked 25 degrees C > 4 degrees C > 37 degrees C. [tdh] (Mus musculus) PubMed

 13670.

The sequencing result showed that the length of Anfae A was 783bp and encoding 260 amino acids.[FaeA] (Mus musculus) PubMed

 13671.

we proposed a plausible mechanism for the phenolic alpha-glucosydase inhibitor's binding, since the mechanism of inhibition has not yet been elucidated. (Mus musculus) PubMed

 13672.

Cmwc-1 mRNA was light inducible and the expression level increased significantly after irradiation in all tested strains.[Cmwc-1] (Mus musculus) PubMed

 13673.

The active site residues examined are responsible for tuning the protonation steps that occur during catalysis, likely through extensive hydrogen bonding, but are not necessarily required for the reaction to proceed.(ccNir, cytochrome c nitrite reductase) (Mus musculus) PubMed

 13674.

The optimal pH and temperature of the EstS1 were 8.0 and 70 degrees C and the half-life is at 60 degrees C was 15 h. [EstS1] (Mus musculus) PubMed

 13675.

restraint stress experiments were performed to identify activated arginine vasotocin (AVT) neurons (parvocellular or magnocellular) using immunocytochemistry.[Arginine Vasotocin] (Mus musculus) PubMed

 13676.

It was demonstrated that knockdown of elongation factor 1-alpha (EF1A) impairs N protein proliferation and transmissible gastroenteritis coronavirus replication in host cells.[EF1A] (Mus musculus) PubMed

 13677.

These results suggest that the waaL gene functions on the APEC LPS synthesis and bacterial pathogenesis.[waaL] (Mus musculus) PubMed

 13678.

Authors conclude that Scl-1 is a virulence determinant in the M1T1 group A Streptococcus clone, allowing it to subvert innate immune functions that are critical in clearing bacterial infections.[Scl-1] (Mus musculus) PubMed

 13679.

Neurovirulence protein ICP34.5 produces up to 4 distinct polypetides from its gamma34.5 open reading frame. [ICP34.5] (Mus musculus) PubMed

 13680.

lactate dehydrogenase expression was more intense in trophozoites and immature first-generation schizonts, but decreased in mature first-generation schizonts [new entry] (Mus musculus) PubMed

 13681.

These data indicate that type II Toxoplasma gondii GRA15II induction of CD40 promotes parasite immunity through the production of IL-12.[GRA15] (Mus musculus) PubMed

 13682.

The crystal structure of the light chain of medaka enteropeptidase (MEPL) was solved to gain insights into the determinants for its stricter specificity.[MEPL] (Mus musculus) PubMed

 13683.

Activation of soluble guanylyl cyclase (sGC) by YC-1 leads to liver X receptor alpha-dependent upregulation of ABCA1 in macrophages and may confer protection against atherosclerosis. (Mus musculus) PubMed

 13684.

F123 in Staph aureus biotin protein ligase (BPL) has novel roles in both protein dimerization and ligand-binding that have not been reported in E coli BPL [BPL] (Mus musculus) PubMed

 13685.

STF recruits corepressors to transcriptionally repress its targets during leaf blade morphogenesis.[STF, TPLC, AS2] (Mus musculus) PubMed

 13686.

OsZHD1 plays a key roles in rice morphogenesis, especially in the modulating of leaf rolling, which provided a novel insight into the molecular mechanism of leaf development in rice. (Mus musculus) PubMed

 13687.

Deletion of YlCTS1 remarkably reduced extracellular endochitinase activity in the culture supernatant of Yarrowia lipolytica and enhanced cell aggregation.[YlCts1p] (Mus musculus) PubMed

 13688.

Trypanosoma brucei 427 alternative oxidase (TAO) possesses both an N-terminal and internal mitochondrial targeting signal. [TAO] (Mus musculus) PubMed

 13689.

the Vibrio cholerae colonization factor GbpA is an active lytic polysaccharide monooxygenase. [GbpA] (Mus musculus) PubMed

 13690.

Although BCR1 leads to the formation of more and longer pseudohyphae, it was not required for initial adhesion and formation of mature biofilms in strains with a high level of biofilm formation. [BCR1] (Mus musculus) PubMed

 13691.

Ste18 is a positive control element in the mating process of Candida albicans. [Ste18] (Mus musculus) PubMed

 13692.

In amebae, low molecular weight protein tyrosine phosphatase was expressed at low but detectable levels as detected by immunoprecipitation followed by immunoblotting.[low molecular weight protein tyrosine phosphatase] (Mus musculus) PubMed

 13693.

These results indicate active roles for TolCV1 and TolCV2 in the physiology of Vibrio vulnificus.[TolCV1 and TolCV2] (Mus musculus) PubMed

 13694.

XA10 is an inducible, intrinsic terminator protein that triggers programmed cell death by a conserved mechanism involving disruption of the ER and cellular Ca(2+) homeostasis. [XA10] (Mus musculus) PubMed

 13695.

GPA3 acts synergistically with Rab5a and VPS9a to regulate DV-mediated post-Golgi traffic in rice. [GPA3] (Mus musculus) PubMed

 13696.

UfSP2 proteins have protease- and Ufm1-independent functions in GPCR biogenesis. (Mus musculus) PubMed

 13697.

These findings reveal a new function for cleavage factor I in the DNA damage response and underscore the importance of coordinating transcription termination with replication in the maintenance of genomic stability. (Mus musculus) PubMed

 13698.

Collectively, these studies suggest that, despite the overlapping roles of AdcA and AdcAII in zinc acquisition, they may have unique mechanisms in zinc homeostasis and act in a complementary manner during host colonization.[AdcAII] (Mus musculus) PubMed

 13699.

Sfh3 modulates the efficiency with which a neutral lipid hydrolase-rich LD subclass is consumed during biogenesis of specialized membrane envelopes that package replicated haploid meiotic genomes. (Mus musculus) PubMed

 13700.

CaExo84 is phosphorylated by Cdk1, which is necessary for efficient hyphal extension. This action of Cdk1 depends on the hyphal-specific cyclin Hgc1, the homologue of G1 cyclins in budding yeast.[Exo84, Cdk1, Hgc1] (Mus musculus) PubMed

 13701.

ALCOHOL DEHYDROGENASE 1 is essential for sugar metabolism via glycolysis to ethanol fermentation in both the embryo and endosperm. In the endosperm energy is presumably needed for synthesis of the amylases and for sucrose synthesis in the endosperm.[adh1] (Mus musculus) PubMed

 13702.

AbrC3 directly controls actinorhodin production by binding to the actII-ORF4 promoter region.[AbrC3] (Mus musculus) PubMed

 13703.

The temporal inverse regulation of exopolysaccharides and pili by ExpR enables Sinorhizobium meliloti to achieve a coordinated expression of cellular processes during early stages of host interaction.[ExpR] (Mus musculus) PubMed

 13704.

This work demonstrates that PerR regulates manganese homeostasis in Streptococcus oligofermentans, which is critical to H2O2 stress defenses and may be distributed across all oral streptococci lacking catalase.[PerR] (Mus musculus) PubMed

 13705.

Collectively, these results suggest a role for Mfr in maintaining iron homeostasis in H2 O2 stressed Campylobacter jejuni, probably via affecting the concentrations of intracellular iron.[Mfr] (Mus musculus) PubMed

 13706.

Sequence and mutational analysis demonstrated that galE encodes a UDP-galactose 4-epimerase (EC 5.1.3.2), which catalyzes the interconversion of UDP-galactose and UDP-glucose.[galE] (Mus musculus) PubMed

 13707.

To investigate the molecular players underlying the formation of en passant synapses and each individual step, Caenorhabditis elegans nematodes lacking the v-SNARE master protein 1 were studied (Mus musculus) PubMed

 13708.

These studies support our proposal that Cox3p and Cox1p are separate assembly modules with unique compositions of ancillary factors and subunits derived from the nuclear genome.[Cox3] (Mus musculus) PubMed

 13709.

These findings reveal phosphatidylinositol 3,5-bisphosphate as a general regulator of TORC1.[TORC1] (Mus musculus) PubMed

 13710.

The regulation of Rgf1p could be part of the mechanism by which Cds1p and Rad24p promote survival in the presence of chronic replication stress.[Rgf1p] (Mus musculus) PubMed

 13711.

Investigation of the donor substrate specificity of the N-acetylglucosaminyltransferase activities of P. multocida heparosan synthase 2 (PmHS2) and E. coli K5 KfiA indicates the substrate promiscuities of PmHS2 and KfiA.[HS2, KfiA] (Mus musculus) PubMed

 13712.

Cellobiose transport assays with the resulting strains indicated that CDT-1 is a proton symporter while CDT-2 is a simple facilitator.[CDT-1, CDT-2] (Mus musculus) PubMed

 13713.

The N-terminal 98 amino acids of PevD1 retained the ability to induce systemic acquired resistance against tobacco mosaic virus (TMV) but not induction of hypersensitive response.[PevD1] (Mus musculus) PubMed

 13714.

These results suggested that the budC gene product belongs to a NAD(H)-dependent meso-2,3-butanediol dehydrogenase.[budC] (Mus musculus) PubMed

 13715.

In vitro validation confirmed that PhoB, a protein which is only active during phosphate limitation, was responsible for xds activation.[PhoB, xds] (Mus musculus) PubMed

 13716.

Authors proposed that tandem repeated SH3_3 domains of Psm recognized the peptide side-chains of peptidoglycans to assist the catalytic domain hydrolysing the glycan backbone.[Psm] (Mus musculus) PubMed

 13717.

The QsuR tetramer senses the accumulation of chorismate and activates qsu genes that promote the quinate/shikimate catabolic instead of the aromatic compounds biosynthetic route.[QsuR] (Mus musculus) PubMed

 13718.

aid1 overexpression enhances the ability of F. nucleatum to form biofilms with oral streptococci and alters biofilm morphology [aid1] (Mus musculus) PubMed

 13719.

In this communication, authors describe evidence demonstrating the capacity of Atl, the major Staphylococcus aureus autolytic enzyme to bind DNA.[Atl] (Mus musculus) PubMed

 13720.

The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling. [PQBP1] (Mus musculus) PubMed

 13721.

OsJAR1 is a JA-amino acid synthetase that is required for optimal flower opening and closing and anther dehiscence in rice. (Mus musculus) PubMed

 13722.

OsRZFP34 modulates gene expression to control stomata opening. (Mus musculus) PubMed

 13723.

Tryptophan187, which mediates intermolecular effector domain interactions in NS1A, is also required for cooperative double-sstranded RNA binding. [NS1A], H3N2 influenza A virus. (Mus musculus) PubMed

 13724.

Transcriptomic analysis showed that the expression of 186 genes was altered in the ccaR-deleted mutant.[CcaR] (Mus musculus) PubMed

 13725.

Pcdh18b and Nap1 regulate axon arborization by affecting the density of filopodia along the shaft of the extending axon. [Nap1] (Mus musculus) PubMed

 13726.

CCZ-1 and the HOPS complex are essential for the biogenesis of gut granules, cell type-specific, lysosome-related organelles that coexist with conventional lysosomes in Caenorhabditis elegans intestinal cells, independent of RAB-7 and SAND-1.[RAB-7] (Mus musculus) PubMed

 13727.

XAWP1 functions as a mediator of Wnt signaling to regulate NC specification [XAWP1] (Mus musculus) PubMed

 13728.

AP-1(c-Jun/FosB) may play a role in neurogenesis via the induction of FoxD5b expression during early vertebrate development [FosB] (Mus musculus) PubMed

 13729.

DWT1 activity in the internode elongation is directly or indirectly associated with gibberellin signaling (Mus musculus) PubMed

 13730.

GLUT3 is critically important for brain organogenesis and embryonic growth.[GLUT3] (Mus musculus) PubMed

 13731.

Two, two, five, and two haplotypes were identified at the TaSus2-2A, TaSus2-2B, TaSus1-7A, and TaSus1-7B loci, respectively.[Sus1, Sus2] (Mus musculus) PubMed

 13732.

The cytidine diphosphate-diacylglycerol synthase conditional knockout showed morphological changes including a cell-cycle arrest due in part to kinetoplast segregation defects.[cytidine diphosphate-diacylglycerol synthase] (Mus musculus) PubMed

 13733.

These results support a role for NspS in signal transduction in response to norspermidine and spermidine, but not their transport.[NspS] (Mus musculus) PubMed

 13734.

effects of Pi deprivation on the molecular mechanisms involved in EHEC survival and virulence under Pho regulon control [PhoB] (Mus musculus) PubMed

 13735.

Rre37 is a pathway-level regulator that activates the metabolic flow from glycogen to polyhydroxybutyrate.[Rre37] (Mus musculus) PubMed

 13736.

GDH could catalyze the interconversion of (3S)-acetoin/meso-2,3-butanediol and (3R)-acetoin/(2R,3R)-2,3-butanediol. [GDH] (Mus musculus) PubMed

 13737.

Analyses provide evidence that CcpA regulates the genes of the central carbon metabolism by binding either the pseudo-palindromic cre motif or the cre2 motif in a HPr(Ser) approximately P independent conformation. (Mus musculus) PubMed

 13738.

Results report identification and characterization of lfd-1, encoding a single pass transmembrane protein, which is also involved in membrane merger during cell fusion in Neurospora crassa.[LFD-1] (Mus musculus) PubMed

 13739.

The study reports the X-ray structure of MepB to 2.1 A revealing its structural similarity to the PD-(D/E)XK family of endonucleases. [MepB] (Mus musculus) PubMed

 13740.

The structure and distribution of a specific class of A. fumigatus long interspersed nuclear element (LINE)-like retrotransposons occupying subtelomeric loci, and their stability in response to laboratory- and host-imposed stresses is investigated. [LINE] (Mus musculus) PubMed

 13741.

The tight association of the PfI2 regulator to PP1, mediated by a two-site interaction, is necessary to exert its function. [PfI2] (Mus musculus) PubMed

 13742.

FrxA contributes to the successful chronic colonization ability that characterizes H. pylori. [FrxA] (Mus musculus) PubMed

 13743.

Purified and studied a novel fructosyltransferase (AoFT) from Aspergillus oryzae capable of synthesizing sucrose 6-acetate (S6A) from sucrose and glucose 6-acetate. (Mus musculus) PubMed

 13744.

These data enlighten the crucial role of MtCP6 and MtVPE in the onset of nodule senescence.[MtCP6 and MtVPE] (Mus musculus) PubMed

 13745.

RON12, unlike most other RONs is not essential, but deletion of the gene does affect parasite proliferation.[RON12] (Mus musculus) PubMed

 13746.

Data indicate that the two cytosolic ascorbate peroxidases (cAPXs) are not essential for photosynthesis: [APX1 and APX2] (Mus musculus) PubMed

 13747.

fibronectin extra domain A (Fn(EDA)) is an endogenous TLR4 ligand markedly elevated in the circulation and lesional skin biopsies from patients with scleroderma, as well as in mice with experimentally induced cutaneous fibrosis.[FnEDA] (Mus musculus) PubMed

 13748.

These data indicate that the RNAi-mediated silencing of acuD expression could attenuate virulence of Penicillium marneffei.[acuD] (Mus musculus) PubMed

 13749.

The cfl1Delta/Delta mutant exhibited highly attenuated virulence and reduced fungal burdens in the mouse systemic infection model, indicating that CFL1 might be a potential target for antifungal drug development.[CFL1] (Mus musculus) PubMed

 13750.

PPLP2-deficient [PPLP2(-)] merozoites show normal egress dynamics during the erythrocytic replication cycle, but activated PPLP2(-) gametocytes were unable to leave erythrocytes and stayed trapped within these cells.[PPLP2] (Mus musculus) PubMed

 13751.

The genetic diversity of the most variable domain of vaccine candidate MSP1 protein has been assessed. [MSP1] (Mus musculus) PubMed

 13752.

Overexpression of PvRbohB augmented nodule efficiency by enhancing nitrogen fixation and delaying nodule senescence, but impaired arbuscular mycorrhizal fungal colonization.[RbohB] (Mus musculus) PubMed

 13753.

Overexpression of OsBURP16 caused pectin degradation and affected cell wall integrity as well as transpiration rate, which decreased tolerance to abiotic stresses.[OsBURP16] (Mus musculus) PubMed

 13754.

Both hydrophilic regions in the movement protein have RNA-binding activity and mutational analysis reported that either deletion of any of these regions, or loss of the basic amino acids, interfered with the viral intercellular movement.[movement protein] (Mus musculus) PubMed

 13755.

Two chloroplast-localized proteins (OsCP12 and OsRP1) interacted with OsCTR1 in the cytosol, and ubiquitination by OsCTR1 led to protein degradation via the Ub 26S proteasome.[OsCTR1, OsCP12 and OsRP1] (Mus musculus) PubMed

 13756.

study reports cloning and characterization of cysteine-rich neurotrophic factor (apCRNF); results show that apCRNF is a native neurotrophic factor in Aplysia that can engage the molecular and synaptic mechanisms underlying memory formation [CRNF] (Mus musculus) PubMed

 13757.

lncPrep+96kb could play a role in the POP gene activation in the granulosa cell.[lncPrep+96kb] (Mus musculus) PubMed

 13758.

The nuclear-encoded OsDG2 plays important roles in chloroplast development at early leaf stage of rice. (Mus musculus) PubMed

 13759.

TaPP2AbB"-alpha, in conjunction with the other two PP2A subunits, is involved in multi-stress response, and positively regulates lateral root development under osmotic stress [PP2AbB] (Mus musculus) PubMed

 13760.

OsSWEET5 plays a crucial role in regulating the crosstalk between sugar and auxin in rice [SWEET5] (Mus musculus) PubMed

 13761.

PAN1 and PAN2 are not dedicated to subsidiary mother cell polarization but instead play broader roles in plant development.[PAN1, PAN2] (Mus musculus) PubMed

 13762.

A positive feedback loop formed by two heat-inducible genes, HEAT SHOCK PROTEIN101 (HSP101) and HEAT STRESS-ASSOCIATED 32-KD PROTEIN (HSA32), at the posttranscriptional level prolongs the effect of heat acclimation in rice seedlings.[HSA32, HSP101] (Mus musculus) PubMed

 13763.

Mutation of veA caused a dramatic down-regulation of transcription of a polyketide synthase gene belonging to cluster 27 and the loss of the ability of the fungi to produce sclerotia. [veA] (Mus musculus) PubMed

 13764.

This study showed that reducing conditions and mutations in the disulfide bonding system caused hyperactivation of YfiN and subsequent CsgD-independent cellulose production. (Mus musculus) PubMed

 13765.

The ability to utilize choline as a sole nitrogen source correlated strongly with the presence of a putative Rieske non-haem iron protein homologous to bacterial ring-hydroxylating oxygenases and plant choline monooxygenases named CMO1.[CMO1] (Mus musculus) PubMed

 13766.

These results suggest that OsPT9 and OsPT10 redundantly function in phosphate uptake.[OsPT9, OsPT10] (Mus musculus) PubMed

 13767.

The subcellular location of notch intracellular domain 1 (NICD1) appears to determine whether TGF-beta signaling will be inhibited or not. [Notch1] (Mus musculus) PubMed

 13768.

Binding of streptokinase Lys(414) to plasminogen kringle 4 plays a role in recognition of plasminogen by streptokinase.[SK] (Mus musculus) PubMed

 13769.

The first crystal structure of mature Staphylococcus simulans lysostaphin and two structures of its isolated catalytic domain. [lysostaphin] (Mus musculus) PubMed

 13770.

OsRDR1 plays a role in regulating a substantial number of endogenous genes with diverse functions in rice through small RNA-mediated pathways.[RDR1] (Mus musculus) PubMed

 13771.

COP1 protein sequences from Physcomitrella, rice and Arabidopsis have been functionally conserved during evolution, while the SPA proteins showed considerable functional divergence.[COP1, SPA] (Mus musculus) PubMed

 13772.

COP1 protein sequences from Physcomitrella, rice and Arabidopsis have been functionally conserved during evolution, while the SPA proteins showed considerable functional divergence.[COP1, SPA] (Mus musculus) PubMed

 13773.

Data indicate that EscO is the virulence counterpart of the flagellar FliJ protein, and is a positive regulator of EscN ATPase activity.[EscO; EscN] (Mus musculus) PubMed

 13774.

three (with frequencies>1%) single nucleotide polymorphisms (SNPs) of the KAP6 gene, one SNP of the KAP7 gene, and five SNPs of the KAP8 gene were detected (Mus musculus) PubMed

 13775.

This study demonstrated the existence of low sequence variation in the eIF4A gene, suggesting that T. gondii eIF4A may represent a suitable candidate vaccine against toxoplasmosis. (Mus musculus) PubMed

 13776.

This study is the first to demonstrate the nucleic acid-binding and synthetic capabilities of a betanecrovirus polymerase,p50 replicase.[p50] (Mus musculus) PubMed

 13777.

Glycosylation affects the oligomerisation of TibA and that unglycosylated TibA is locked in a conformation that is not suited for adhesion.[TibA] (Mus musculus) PubMed

 13778.

Various redox-altering compounds and osmotica had differential effects on glutathione disulphide content and reduction potential, and consequently on the expression of the flowering repressor ZCCT2 in the winter wheat Ch and the spring wheat Tsp.[ZCCT2] (Mus musculus) PubMed

 13779.

Ectopic overexpression of OsKMD2 in Arabidopsis results in decreased cytokinin sensitivity.[OsKMD2] (Mus musculus) PubMed

 13780.

The combined results show that Vibrio vulnificus AphA upregulates iscR expression by antagonizing its negative autoregulation.[AphA] (Mus musculus) PubMed

 13781.

These findings reveal key features of the architecture of the gene-regulatory network centered on DAF-16, and raise the possibility that activation of AMP-independent AMPK in nutritionally replete daf-2 mutant adults slows aging in C. elegans (Mus musculus) PubMed

 13782.

These findings advance the current understanding of rapamycin-TOR signaling in plants.[FKBP12] (Mus musculus) PubMed

 13783.

RSS3 plays a role in the coordinated control of root elongation and cell wall plasticity in the root apex.[RSS3] (Mus musculus) PubMed

 13784.

The study reports on the biophysical characterization of the structure and thermal stability of AzoC, an azoreductase, by using a wide range of biophysical tools. [AzoC] (Mus musculus) PubMed

 13785.

All the results suggested that microRNA-454 (miR-454) could provide a novel therapeutic approach for treating liver fibrosis, especially the liver fibrosis induced by Schistosoma japonicum.[miR-454] (Mus musculus) PubMed

 13786.

The effect of lptD, cdsA, and plsC mutations on phosphatidic acid accumulation and vancomycin resistance in multiple E. coli strains are reported.[cdsA; lptD; plsC] (Mus musculus) PubMed

 13787.

crystal structures representing the phosphoenzyme ground state (E2P) and a dephosphorylation intermediate (E2.Pi) of ZntA from Shigella sonnei, determined at 3.2 A and 2.7 A resolution, respectively (Mus musculus) PubMed

 13788.

PAF is involved in the regulation of the autophagyand apoptosis. [PAF] (Mus musculus) PubMed

 13789.

this study discovered transcription factors Bl (Bitter leaf) and Bt (Bitter fruit) that regulate this pathway in leaves and fruits, respectively. [Bl][Bt] (Mus musculus) PubMed

 13790.

Complementation analysis of the mcpU deletion strain verified McpU as the key proline sensor.[McpU] (Mus musculus) PubMed

 13791.

VPA0451 is the cognate chaperone for the effector VPA0450 and is the second type III secretion systems (T3SS) chaperone identified to date. [VPA0450 and VPA0451, strain BCC23] (Mus musculus) PubMed

 13792.

The active form of vitamin B6, pyridoxal is a cofactor for a variety of essential enzymes present in the malaria parasite which includes the ornithine decarboxylase , the aspartate aminotransferase and the serine hydroxymethyltransferase (Mus musculus) PubMed

 13793.

These data demonstrate that not only the C terminus but also the DNA binding domain of LeuO is involved in oligomer formation.[LeuO] (Mus musculus) PubMed

 13794.

Expression of HBSP significantly increased the formation of BPDE-DNA adduct in benzo[alpha]pyrene-treated Huh-7 hepatoma cells, and this enhancement was blocked by knockdown of microsomal epoxide hydrolase (Mus musculus) PubMed

 13795.

This study revealed essential roles of TcLEC2 during both zygotic and somatic embryo development.[TcLEC2] (Mus musculus) PubMed

 13796.

the present work indicated that LF stimulated MC3T3-E1 preosteoblast differentiation mainly through LRP1-independent PKA and p38 signaling pathways. (Mus musculus) PubMed

 13797.

When Tax/Rex expression is muted and HBZ is dominant, latent infection is established with expression of regulatory (Tax/Rex/HBZ) but not structural proteins. (Mus musculus) PubMed

 13798.

Haplotypes of TaGW2-6B and their effects on TKW and interaction with haplotypes at TaGW2-6A, were examined.[TaGW2] (Mus musculus) PubMed

 13799.

The role of emp4 during post-germinative development, was investigated.[emp4] (Mus musculus) PubMed

 13800.

a role for S. pneumoniae PhtD as a Zn(2+) scavenger for later release to the surface transporter AdcAII, leading to Zn(2+) uptake [PhtD][AdcAII] (Mus musculus) PubMed

 13801.

the binding mode of Ler to DNA and its mechanism in alleviating genes repressed by H-NS [H-NS][Ler] (Mus musculus) PubMed

 13802.

Data indicate that the PEST sequence (rich in proline, glutamic acid, serine, and threonine) of the spermine synthase 1 (ZmSPMS1) leads to specific degradation of the beta-Glucuronidase (GUS) reporter protein: [ZmSPMS1] (Mus musculus) PubMed

 13803.

Analysis of the chain-length distribution in amylopectin of the double mutant lines showed that SSI and BEI or BEIIb primarily function independently, and branching by BEIIb is followed by SSI chain elongation.[SSI, BEI, BEIIb] (Mus musculus) PubMed

 13804.

OsREX1-S renders host plants tolerant to Cadmium, ultraviolet b radiation, bleomycin and mitomycin C through the enhanced DNA excision repair.[OsREX1-S] (Mus musculus) PubMed

 13805.

Coimmunoprecipitation studies and proximity ligation assays indicated that integrin alphavbeta3 interacts with herpes simplex virus type 2 glycoprotein H (gH). (Mus musculus) PubMed

 13806.

Authors propose a model in murine cytomegalovirus virion-associated protein M45 delivered by viral particles activates NF-kappaB, presumably involving an interaction with RIP1 and NEMO. (Mus musculus) PubMed

 13807.

ELF1 ubiquitinates target proteins through an interaction mediated by ARM repeats.[ELF1] (Mus musculus) PubMed

 13808.

Loss of fibronectin-binding proteins reduced the initial adherence of bacteria, indicating that these proteins are also involved in primary attachment. [FnBPA and FnBPB, Strain BH1CC] (Mus musculus) PubMed

 13809.

The N-acetylglutamate synthase Cg3035 is able to catalyse the first step of arginine biosynthesis in C. glutamicum. (Mus musculus) PubMed

 13810.

Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase dependent manner.[Caspase 1] (Mus musculus) PubMed

 13811.

The results clearly identify SbmA as a carrier of naked PNA over the inner bacterial membrane and thereby infer that the peptide is transporting the PNA conjugates over the outer membrane.(SbmA protein, E coli) (Mus musculus) PubMed

 13812.

LjNSP2 interacts with itself to form a homodimer and this depends on the SH2-like domain.[NSP2] (Mus musculus) PubMed

 13813.

These results show that DAP1 is a key regulator, of the induction of apoptosis and reduction of autophagy by subtilase cytotoxin (SubAB).[SubAB] (Mus musculus) PubMed

 13814.

This study showed that enteropathogenic Escherichia coli through the T3SS-dependent translocation of NleF, induces a proinflammatory response in an NF-kappaB-dependent manner in the early stages of infection.[NleF] (Mus musculus) PubMed

 13815.

purification of the supernatants of the producer yeasts permitted recovery of the bacteriocins EntA and BacE50-52. Both purified bacteriocins were active against Gram-positive bacteria (Mus musculus) PubMed

 13816.

Trm1p is a key regulator of methanol metabolism in the yeast, Pichia pastoris.TRM1 regulates the expression of genes of methanol utilization pathway. (Mus musculus) PubMed

 13817.

(Protein Kinase G) Protein Kinase G was found to regulate specific sensory responsiveness and social organization in honey bees. (Mus musculus) PubMed

 13818.

Naringenin inhibits the growth of dictyostelium discoideum in TRPP2 dependent manner. (Mus musculus) PubMed

 13819.

inhibition of colon cancer progression is dictated by quantitatively controlling expression of the miR-17~92 cluster.[miR17-92] (Mus musculus) PubMed

 13820.

These findings demonstrate that the ahemolytic pneumolysin (PLYa) has the potential to manipulate host immunity irrespective of capsule type.[PLYa] (Mus musculus) PubMed

 13821.

ROP5 uses a highly polymorphic surface to bind adjacent to the nucleotide-binding domain of an IRG and that this produces a profound allosteric change in the IRGa6 structure. [Rop5] (Mus musculus) PubMed

 13822.

Rhodococcus erythropolis A4 nitrile hydratase and amidase were found to be effective at hydrolysing cyanohydrins and 2-hydroxyamides, respectively.[nitrile hydratase, amidase] (Mus musculus) PubMed

 13823.

OsKAT2 may be a functional ortholog of AtKAT1 in rice.[OsKAT2] (Mus musculus) PubMed

 13824.

The study defines domains of ShlB which are important for ShlA secretion and activation.[ShlA, ShlB] (Mus musculus) PubMed

 13825.

GBS RNA, along with lysosomal components including cathepsins, leaks out of lysosomes and interacts with NLRP3 to induce IL-1beta production (Mus musculus) PubMed

 13826.

FimY functions as a DNA-binding protein to activate fimZ, and a FimY-FimZ protein complex may form to regulate other fim genes. [fimZ, fimY] (Mus musculus) PubMed

 13827.

channelopsin-2 (Chop2, protein without bound retinal) is much more prone to degradation than channelrhodopsin-2 (protein with retinal) [channelrhodopsin-2] (Mus musculus) PubMed

 13828.

The effect of deletion of arginine deminiase (arcA1 and ArcA2) to assess the function of the arginine deiminase (ADI) pathway in organic acid resistance and biofilm formation of Staphylococcus epidermidis 1457 is reported.[arcA1; arcA2] (Mus musculus) PubMed

 13829.

Cas2 protein has pH-dependent nuclease activity against double-stranded DNA. (Mus musculus) PubMed

 13830.

MiR-3 facilitates BmNPV infection by modulating the expression of viral P6.9 and other late genes in Bombyx mori. [Mir-3] (Mus musculus) PubMed

 13831.

This study demonstrates, for the first time, that the putative vacuolar calcium channel Yvc1 plays an important role in Candida albicans infection and survival in host tissues.[Yvc1] (Mus musculus) PubMed

 13832.

A new alpha-l-arabinofuranosidase was isolated, cloned, and characterized. It is constitutively expressed and acts as a debranching enzyme for single-substituted arabinosyl side chains of 1-arabinan. PcABF43A. (Mus musculus) PubMed

 13833.

In summary, Staphylococcus aureus GdpS contributes to cell-to-cell interactions during early biofilm formation by influencing expression of lrgAB and cidABC mediated eDNA release.[GdpS] (Mus musculus) PubMed

 13834.

The study presents the structure of the Nipah virus unassembled nucleoprotein in complex with its viral chaperone the phosphoprotein. [nucleoprotein] (Mus musculus) PubMed

 13835.

Authors describe SiiA and SiiB as new, exclusively virulence-associated members of the Mot/Exb/Tol family of membrane proteins involved in a novel mechanism of controlling Salmonella Pathogenicity Island 4-dependent adhesion.[SiiA, SiiB] (Mus musculus) PubMed

 13836.

After intraventricular injection of S. pneumoniae, the expression of NT-4/5 in the pallium and hippocampus in juvenile rats was increased, especially during early disease course. (Mus musculus) PubMed

 13837.

miR444a plays multiple roles in the rice NO3--signaling pathway in nitrate-dependent root growth, nitrate accumulation and phosphate-starvation responses. [miR444a] (Mus musculus) PubMed

 13838.

The NisK/NisR system plays a significant role in pathogenesis, both in colonization and invasive disease. [NisK,NisR] (Mus musculus) PubMed

 13839.

overexpression of SNAC1 improve more tolerance to drought and salt in cotton through enhanced root development and reduced transpiration rates.[SNAC1] (Mus musculus) PubMed

 13840.

OsmiR396d regulates the expression of OsGRF genes, which function with OsGIF1 in floret development through targeting of JMJ706 and OsCR4.[OsmiR396d, OsJMJ706, OsGRF6,OsGRF10] (Mus musculus) PubMed

 13841.

In the absence of Rubisco and PGR5, a sustained electron flow is maintained with molecular oxygen instead of carbon dioxide serving as the terminal electron acceptor.[PGR5, ATPase] (Mus musculus) PubMed

 13842.

betaC1 is a pathogenicity determinant for Ageratum yellow leaf curl betasatellite.[betaC1] (Mus musculus) PubMed

 13843.

cl7(t) had a single nucleotide substitution (C to A) in the third exon that leads to a Ser substitution with a stop codon, giving a truncated DEP2 protein. There was lower CL7(t) expression level in spikelets and weaker signals in lodicules.[CL7(t)] (Mus musculus) PubMed

 13844.

betaC1 is a pathogenicity determinant for Wheat dwarf India virus. [betaC1] (Mus musculus) PubMed

 13845.

Co-immunoprecipitation and yeast two-hybrid analysis show that the secretion ATPase PilB1 (a component of the type IV pilus base) is an interaction partner of Hfq.[Hfq, PilB1] (Mus musculus) PubMed

 13846.

The transcription initiation pathway of mutant P266L T7 RNA polymerase, was investigated with the goal of understanding the mechanistic basis for short and long abortive synthesis.[RNAP] (Mus musculus) PubMed

 13847.

The trypanosome Splicing Factor, SF3a60, the only currently annotated SF3a component, was characterized.[SF3a60] (Mus musculus) PubMed

 13848.

The activity of IreB is modulated by IreK-dependent phosphorylation in a signaling pathway required for cephalosporin resistance. [IreB],[IreK] (Mus musculus) PubMed

 13849.

The study explores molecular interactions between thiostrepton and the TipAS protein from Streptomyces lividans. [TipAS] (Mus musculus) PubMed

 13850.

The mutant which lost the lipid-binding activity showed defect in pexophagy, suggesting that phosphoinositide 3-phosphate-binding activity of PpAtg21 was required for pexophagy.[Atg21] (Mus musculus) PubMed

 13851.

The interaction of LEC-1 and MIG-6 in the pharynx may affect susceptibility to paraquat and that LEC-10 has different functions from LEC-1 in regulating H2O2 and paraquat resistance in the intestine.(Lec-1 protein, C elegans) (Mus musculus) PubMed

 13852.

OsAHPs function as positive regulators of the cytokinin signaling pathway and play different roles in salt and drought tolerance in rice.[OsAHP1, OsAHP2] (Mus musculus) PubMed

 13853.

Among the three Ras proteins, YlRas2 plays a major role in the regulation of dimorphic transition, YlRas1 plays a minor role in this process while the additional Ras protein, YlRas3, does not seem to have a role in dimorphic transition.[Ras1, Ras2, Ras3] (Mus musculus) PubMed

 13854.

mutations in the zinc-binding domain of Apobec2 diminish its ability to stimulate Pou6f2 binding to DNA, and knockdown of Ubc9 or Pou6f2 suppressed retina regeneration [Apobec2] (Mus musculus) PubMed

 13855.

Fertilization-Independent Endosperm1 (OsFIE1) was sensitive to temperature changes, and its expression was negatively correlated with the duration of the syncytial stage during heat stress.[osFIE1] (Mus musculus) PubMed

 13856.

The IDCases can catalyze decarboxylation of 5caC to C albeit with weak activity, which is the first in vitro evidence for direct decarboxylation of 5caC to C by an enzyme.(isoorotate decarboxylase) (Mus musculus) PubMed

 13857.

The IDCases can catalyze decarboxylation of 5caC to C albeit with weak activity, which is the first in vitro evidence for direct decarboxylation of 5caC to C by an enzyme.(isoorotate decarboxylase) (Mus musculus) PubMed

 13858.

identification of a Nodal-related gene (Ndr) in Hydra magnipapillata, and this gene is essential for setting up an axial asymmetry along the main body axis [Ndr] (Mus musculus) PubMed

 13859.

Native IxscS-1E1 is a tick saliva protein that mediates anti-hemostatic, and potentially inflammatory, functions by inhibiting the actions of thrombin, trypsin and other yet unknown trypsin-like proteases at the tick-host interface.[IxscS-1E1] (Mus musculus) PubMed

 13860.

Data indicate that EDS1 and EDS1-LIKE 2 (EDL2) proteins interact with PHYTOALEXIN DEFICIENT 4 (PAD4), suggesting that EDS1/EDL2 forms a complex with PAD4 to confer resistance: [EDL2 and PAD4] (Mus musculus) PubMed

 13861.

NsdD is a key negative regulator of conidiation and likely exerts its repressive role via downregulating brlA [NsdD] (Mus musculus) PubMed

 13862.

A second CXCR1/2, and a CXCR3a and CXCR3b gene have been cloned in rainbow trout.Trout CXCR1-R3 have distinct tissue expression patterns and are differentially modulated by PAMPs, proinflammatory cytokines and infections. [CXCR1/2, CXCR3a, CXCR3b] (Mus musculus) PubMed

 13863.

This is the first report demonstrating the expression of GPER in human and pig mature sperm (Mus musculus) PubMed

 13864.

Data suggest that, in eIF4G/eif4A complex, eIF4G1 (eukaryotic translation initiation factor 4 gamma) exhibits low-affinity ATP binding site in proximity of ATP-binding cleft of eif4A enhancing ATP binding;. [eif4A; eukaryotic initiation factor-4A] (Mus musculus) PubMed

 13865.

Data suggest N-terminal domain of Cdc5 preferentially binds double-stranded RNA and interacts with RNA structures proposed to be near catalytic core of spliceosome. [cdc5, cell division cycle protein 5, core subunit of NineTeen Complex (NTC)] (Mus musculus) PubMed

 13866.

In the absence of FAK, TarP-mediated F-actin assembly was reduced, highlighting the functional relevance of this interaction. (Mus musculus) PubMed

 13867.

It determined the crystal structure of the unphosphorylated dimeric BaeR from Escherichia coli. The dimer interface is formed by a domain swap at the receiver domain. (Mus musculus) PubMed

 13868.

MYT3, a Myb-like transcription factor, affects fungal development and pathogenicity of Fusarium graminearum. [MYT3] (Mus musculus) PubMed

 13869.

RABL6A prevents centrosome amplification through an ARF/p53-independent mechanism that restricts NPM-T199 phosphorylation. [RABL6A] (Mus musculus) PubMed

 13870.

It has been shown that mutant form GGBP/H152C has relatively low resistance to guanidine hydrochloride denaturing effects. This result indicates the need for more stable proteins to create a sensor for glucose biosensor system. (Mus musculus) PubMed

 13871.

The carboxyl-terminal domain of the epsilon subunit plays a pivotal role in the inhibition of F1 rotation through interaction with other subunits. [F1 epsilon subunit] (Mus musculus) PubMed

 13872.

Characterization of a putative mercaptosuccinate dioxygenase encoded by the gene with the locus tag NC_0022247.1. [mercaptosuccinate dioxygenase] (Mus musculus) PubMed

 13873.

Pisiferdiol could suppress indirectly the action of calcineurin and restored the growth inhibition of the mutant yeast through Ptc1p activation. [PTC1, strain W303-1] (Mus musculus) PubMed

 13874.

CaPtc2p and CaPph3p might play a role in the target of rapamycin (TOR) signaling in C. albicans cells. [PPH3] (Mus musculus) PubMed

 13875.

YlTec1p activates rather than represses gene expression in Yarrowia lipolytica by yeast one-hybrid assay, and YlTec1p is critical for the activation of FLO11-lacZ in Y. lipolytica. [YlTec1p, strain PO1a] (Mus musculus) PubMed

 13876.

from trichomonads and humans when the parasites are grown under iron-depleted conditions. Thus, TvACTN3 could participate in the regulation of gene expression by iron in T. vaginalis through a parallel posttranscriptional mechanism (Mus musculus) PubMed

 13877.

we show that osterix is required for bone formation in a teleost fish and that its important regulatory functions are conserved between teleosts and mammals. (Mus musculus) PubMed

 13878.

These data reveal a new role for the A domain of unprocessed Aap in the attachment phase of biofilm formation and suggest that extracellular protease activity can influence whether Aap contributes to the attachment or accumulation phases.[Aap] (Mus musculus) PubMed

 13879.

The apparent molecular weight of the RstB2 native protein and occurs mostly as a monomer. [RstB2] (Mus musculus) PubMed

 13880.

ROS level was lower in edc3/edc3 cells than in wild-type cells following oxidative stress. CaMCA1 expression was decreased in edc3/edc3 cells. EDC3 plays a critical role in the expression of CaMCA1 and the oxidative stress response in C. albicans (EDC3). (Mus musculus) PubMed

 13881.

The loss of either RNase III or RNase J led to the appearance of a new ribosomal species (the 100S ribosome dimer) during exponential growth and dramatically sensitized these mutants to a range of antibiotics.[RNase J] (Mus musculus) PubMed

 13882.

Lip1 and Lip2 modulates the immune response of primary human macrophages. [Lip1,lip2] (Mus musculus) PubMed

 13883.

The solution structure and dynamics of NC2, a class II hydrophobin. [NC2] (Mus musculus) PubMed

 13884.

Besides its role in development, calcineurin is thus also involved in the stress response in Dictyostelium discoideum.[calcineurin A] (Mus musculus) PubMed

 13885.

Chloroplast-bound IPT1 was almost exclusively responsible for the A37 prenylation of tRNA. [IPT1] (Mus musculus) PubMed

 13886.

Arabidopsis thaliana NAC083 protein interacts with Mungbean yellow mosaic India virus Rep protein. [Rep] (Mus musculus) PubMed

 13887.

the major rice endosperm AGPase activity is controlled by a combination of allosteric regulation and redox control, the latter through modification of the large subunit instead of the small subunit. AGPS2b.AGPL2. (Mus musculus) PubMed

 13888.

SecA was found to be both necessary and sufficient for translocation of secretory proteins with hydrophobic signal sequences, whereas SRP and its receptor improved translocation efficiency.[SecA, SRP] (Mus musculus) PubMed

 13889.

ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice. [ROP5, ROP17, ROP18] (Mus musculus) PubMed

 13890.

Bet protein is a negative regulator of BFV3026 replication. [Bet] (Mus musculus) PubMed

 13891.

Association analyses between two SNPs of MSTN gene and growth traits showed that the individuals with genotype CT and TT of the mutation C1197T had significantly higher body mass, body length and body height than those with genotype CC (P < 0.05). [MSTN] (Mus musculus) PubMed

 13892.

SiiE mediates multiple interactions per molecule with glycoproteins and/or glycosylated phospholipids present in the apical membrane of polarized epithelial cells.[SiiE] (Mus musculus) PubMed

 13893.

The activity of OsAPX in rice roots and shoots are compromised under Cd-stress alone.(ascorbate peroxidase ) (Mus musculus) PubMed

 13894.

RNase E has two alternative RNA binding sites for modulating RNA binding to the catalytic site and the formation of a functional catalytic unit. [RNase E] (Mus musculus) PubMed

 13895.

Hsp90 strengthens the stress response of Paracoccidioides brasiliensis at 37 degrees C through a mechanism that does not involve reactive oxygen species (ROS). Moreover, we suggest that Hsp90 has calcineurin-dependent functions in this organism[HSP90] (Mus musculus) PubMed

 13896.

The results infer the novelty of the alcohol oxidase and its potential biocatalytic application.[Alcohol oxidase] (Mus musculus) PubMed

 13897.

Nuc2 is membrane bound with the C-terminus facing the extracellular environment, indicating it is a signal-anchored Type II membrane protein.[Nuc2] (Mus musculus) PubMed

 13898.

The decrease of L-VGCCs at night by mTORC1 inhibition was in part due to a reduction of L-VGCCalpha1 subunit translocation from the cytosol to the plasma membrane.[L-VGCCalpha1] (Mus musculus) PubMed

 13899.

The epsilon RNA undergoes multiple distinct interactions with P protein as pregenomic RNA encapsidation and replication initiation progress.[P protein] (Mus musculus) PubMed

 13900.

Membrane subfractions were purified from this Synechocystis PCC6803 and MGS activity was assayed.[MGS] (Mus musculus) PubMed

 13901.

OsCPK9 is a positive regulator of abiotic stress tolerance, spikelet fertility, and abscissic acid sensitivity.[OsCPK9] (Mus musculus) PubMed

 13902.

Nsp9 interaction with host retinoblastoma protein benefits the genotype 2 PRRSV replication. [nsp9] (Mus musculus) PubMed

 13903.

This is the first genome-wide stress response analysis in K. lactis and the first demonstration of KlYap8 function. [ KlYap8 ] (Mus musculus) PubMed

 13904.

pneumococcal polysaccharide capsule and pneumolysin differentially affect CXCL8 and IL-6 release from cells of the upper and lower respiratory tract [pneumolysin] (Mus musculus) PubMed

 13905.

The results demonstrate that BmHP1a binds near transcription start sites of highly expressed euchromatic genes and positively regulates their expression (BmHP1a). (Mus musculus) PubMed

 13906.

These findings suggest that OsMYB103L may target cellulose synthase genes for regulation of cellulose synthesis and could potentially be engineered for desirable leaf shape and mechanical strength in rice.[OsMYB103L] (Mus musculus) PubMed

 13907.

zinc-bound YrdD may have an important role in DNA repair by interacting with ssDNA in cells [YrdD] (Mus musculus) PubMed

 13908.

gp120 forms surface immune complexes (ICs) that are also retained for a long time.[gp120] (Mus musculus) PubMed

 13909.

crystal structures of PfRH5 in complex with basigin and two distinct inhibitory antibodies [RH5] (Mus musculus) PubMed

 13910.

The the impact of saeRS on nuclease production plays an important role during the early stages of these infections that is partially offset by increased protease production in sarA mutants.[saeR, saeS, sarA] (Mus musculus) PubMed

 13911.

Altogether these data suggest the phosphatase activity of HrrS and ChrS as key mechanism to ensure pathway specificity and insulation of these two homologous systems.[HrrS and ChrS] (Mus musculus) PubMed

 13912.

Taken together, these results provide new insights into potential roles of GraS in Staphylococcus aureus sensing of HD-CAPs to induce adaptive survival responses to these molecules.[GraS] (Mus musculus) PubMed

 13913.

Report demonstrated that Ybr137wp and the Sgt2 TPR domain interact directly. [Ybr137wp] (Mus musculus) PubMed

 13914.

ORF2 inhibits apoptosis, interacts with Notch1 or Notch3, and interferes with Notch mediated signaling. [ORF2] (Mus musculus) PubMed

 13915.

Activation of gdhA by TamA occurs primarily by a mechanism requiring the TamA DNA binding motif.[gdhA, TamA] (Mus musculus) PubMed

 13916.

A perA null mutant has decreased conidia production, increased susceptibility to triazole antifungal drugs, and is avirulent in a murine model of invasive pulmonary aspergillosis.[PerA] (Mus musculus) PubMed

 13917.

miR-135a-5p suppresses 3T3-L1 preadipocyte differentiation and adipogenesis through the activation of canonical Wnt/beta-catenin signaling by directly targeting adenomatous polyposis coli. [miR-135a-5p] (Mus musculus) PubMed

 13918.

Myxoma virus lacking all four ankyrin-repeat proteins, M-T5, M148, M149 and M150, stimulates multiple cellular anti-viral pathways and exhibits a severe decrease in virulence.[M-T5, M148, M149, M150] (Mus musculus) PubMed

 13919.

HIV matrix protein p17 is pro-fibrogenic through its interactions both with CXCR2 and syndecan-2 on activated HSCs [p17] (Mus musculus) PubMed

 13920.

CrVMP1 knockdown lines showed severe phenotypes, mainly affecting cell division as well as the morphology of cells and organelles.[VMP1] (Mus musculus) PubMed

 13921.

The show that the E. coli ndh gene, encoding NDH-II dehydrogenase, is significantly induced in toxicant-exposed cells and that the enzyme displays tellurite-reducing activity that results in increased superoxide levels in vitro. (Mus musculus) PubMed

 13922.

Homology modelling fits Plasmodium falciparum GCH1 into the classic Tunnelling-fold structure with well-conserved catalytic residues at the active site.[GCH1] (Mus musculus) PubMed

 13923.

Palmitoylation of spike protein S is essential for incorporation into virus-like particles but dispensable for S-M interaction. [S M] (Mus musculus) PubMed

 13924.

AcMNPV gp16 is not essential to virus replication. [gp16] (Mus musculus) PubMed

 13925.

The study reports the discovery of a new protein, Indica Special Protein (ISP), which was only detected in yellow seedlings of indica varieties, and was absent from japonica varieties. [indica special protein] (Mus musculus) PubMed

 13926.

Restricted expression of GSTd4 in silkmoth antennae combined with Glutathione S-transferase activity suggested that GSTd4 was involved in the detoxification of harmful chemicals. [GSTd4] (Mus musculus) PubMed

 13927.

The study characterized the role of the mtfA transcription factor in growth, conidiation, production of gliotoxin, and protease activity, as well as direct assessment of its role in pathogenicity of Aspergillus fumigatus (mtfA). (Mus musculus) PubMed

 13928.

The results suggest a functional role for Pti1-L as a positive regulator of pathogen-defense and salt-stress responses in Cucumis sativus (Pti1-L). (Mus musculus) PubMed

 13929.

This study demonstrated a role of C. albicans SPT20 in overall morphology and distribution of nuclear material, which may cause the defects in filamentation and biofilm formation directly when this gene is deleted.[SPT20] (Mus musculus) PubMed

 13930.

These data support the hypothesis that certain mutations in CagL or recombination events in CagY may serve as a sort of molecular switch or perhaps rheostat in the type IV secretion system.[CagL, CagA] (Mus musculus) PubMed

 13931.

Study provides insight into how CueP confers copper resistance to S. Typhimurium in copper-rich environments such as the phagosome of macrophages. [CueP] (Mus musculus) PubMed

 13932.

A new blaTEM variant (TEM-163) was described in an E. coli strain having an amoxicillin calvulanic acid MIC value of 16/8mug/ml. TEM-163 contains Arg275Gln and His289Leu amino acid substitutions. TEM-163 (Mus musculus) PubMed

 13933.

study found a novel GyrB mutation, E477D, in methicillin-resistant Staphylococcus aureus (MRSA) confers a high level of resistance to third-generation quinolones [GyrB] (Mus musculus) PubMed

 13934.

This study demonistrated that EOL-1, the homolog of the mammalian Dom3Z, regulates olfactory learning in C. elegans. (Mus musculus) PubMed

 13935.

A cysteine-rich domain of CD134 that is critical for binding to the HHV-6B glycoprotein gH/gL/gQ1/gQ2 complex and HHV-6B infection.[gH,gL,gQ1,gQ2] (Mus musculus) PubMed

 13936.

A novel copper transporter gene family, TaCT1, in common wheat, is reported.[TaCT1] (Mus musculus) PubMed

 13937.

VP1 of HPyV6 and HPyV7 does not interact with sialic acid on cultured human cells. [VP1] (Mus musculus) PubMed

 13938.

VP1 of HPyV6 and HPyV7 does not interact with sialic acid on cultured human cells. [VP1] (Mus musculus) PubMed

 13939.

The deletion of the FLX1 gene resulted in respiration-deficient and small-colony phenotype accompanied by a significant ATP shortage and reactive oxygen species unbalance in glycerol-grown cells.[FLX1] (Mus musculus) PubMed

 13940.

An Oryza sativa MAX1 homolog encodes a cytochrome P450 CYP711 that converts strigolactone into ent-2'-epi-5-deoxystrigol. A second rice MAX1 homolog then catalyzes the conversion of ent-2'-epi-5-deoxystrigol to orobanchol. [MAX1] (Mus musculus) PubMed

 13941.

Determined is the crystal structure of McbR to 2.1 A. The structure reveals McbR to be a member of the FadR C-terminal domain (FCD) family of the GntR superfamily of transcriptional regulators. [McbR] (Mus musculus) PubMed

 13942.

The results demonstrated that the region between the endonuclease and reverse transcriptase domains in ORF2, encoded by the ZfL2-2 LINE, is the site at which the protein binds the stem-loop structure of its 3' tail RNA (ORF2 protein). (Mus musculus) PubMed

 13943.

The length of the glycine-rich linker of the DNA-binding domain of HapR is critical for interactions with DNA (HapR). (Mus musculus) PubMed

 13944.

Rhesus rhadinovirus CD200 affects immune responses and viral loads during infection.[CD200, orf15] (Mus musculus) PubMed

 13945.

the role of Isc1 on Pma1 transport and oligomerization [Isc1][Pma1] (Mus musculus) PubMed

 13946.

Therefore, CaRtg3 plays a role in tolerance to cations and antifungal drugs as well as serum-induced filamentation in Candida albicans.[CaRtg3] (Mus musculus) PubMed

 13947.

Clathrin heavy and light chains are expressed in T. cruzi. Both proteins typically localize anterior to the kinetoplast, at the flagellar pocket and Golgi complex region. [clathrin light chain] (Mus musculus) PubMed

 13948.

silkworm cells deficient for FA proteins FancD2 and FancM exhibit normal sensitivities to hydroxyurea (HU) and camptothecin (CPT) [FancM] (Mus musculus) PubMed

 13949.

The differential expression of EhRAD51, EhRAD54, and EhBLM at different times after DNA damage suggests their potential roles in the different steps of homologous recombination(RAD54 and BLM). (Mus musculus) PubMed

 13950.

These results indicate that ptger4b expression is regulated by a genomic mechanism involving Pgr. [PTGER4B] (Mus musculus) PubMed

 13951.

VP24 only very modestly inhibits genome replication and transcription when expressed in a regulated fashion. [VP24] (Mus musculus) PubMed

 13952.

Hrr25 as the kinase that phosphorylates to promote vacuolar transport of alpha-mannosidase Atg34 [alpha-mannosidase] (Mus musculus) PubMed

 13953.

a novel DYW-subclass pentatricopeptide repeat (PPR) protein, PpPPR_45, as a chloroplast RNA editing factor in P. patens [PPR-45] (Mus musculus) PubMed

 13954.

The study reports detailed information about the isolated nucleotide-binding domain of HscA and how the presence of a shortened linker or full-length linker peptide affects its functional properties. [HscA] (Mus musculus) PubMed

 13955.

crystal structures of DHDPS from Campylobacter jejuni with and without its inhibitor bound to the allosteric sites (Mus musculus) PubMed

 13956.

mstA and mstC, have been identified that encode high-affinity glucose transporter proteins.[mstA, mstC] (Mus musculus) PubMed

 13957.

This study has localized to a 71 amino acid region residues important for binding to the two kinds of DNA sites and for RctB dimerization (RctB). (Mus musculus) PubMed

 13958.

CT263 is a bacterial protein with a role in menaquinone synthesis through the futalosine pathway [CT263] (Mus musculus) PubMed

 13959.

Hof1, which has known roles in cytokinesis, also functions during polarized growth by directly controlling the activities of the formin Bnr1.[Hof1, Bnr1] (Mus musculus) PubMed

 13960.

A novel protein phosphatase 5 was cloned and characterized. Site-directed mutagenesis revealed auto-inhibitory roles of the N-terminal region. PP5. (Mus musculus) PubMed

 13961.

Furthermore, hemoglobin binding was impaired in the csa2Delta/Delta mutant compared with the wt and csa2Delta/Delta::CSA2 strains, revealing that Csa2 is involved in the utilization of hemoglobin as an iron source by the hyphal form of Candida albicans.[CSA2] (Mus musculus) PubMed

 13962.

A direct physical interaction between primase and Mcm proteins may facilitate priming reaction by the former protein, suggesting that efficient DNA synthesis through helicase-primase interactions may be conserved.[DNA polymerase alpha-primase] (Mus musculus) PubMed

 13963.

SecA alone is capable of forming a lipid-specific, asymmetric dimer that is able to function as a viable protein-conducting channel in the membrane.[SecA] (Mus musculus) PubMed

 13964.

NuoL subunit is involved in the translocation of both Na(+) and H(+) [NuoL] (Mus musculus) PubMed

 13965.

Identification of the binding sites by which RhlB and RNase D interact with RNase E(RNase E, RhlB and RNase D). (Mus musculus) PubMed

 13966.

Mipu1 overexpression reduces the lipid intake of macrophages and might be associated with the downregulation of CD36 expression in the presence of oxLDL. [Mipu1] (Mus musculus) PubMed

 13967.

Transcriptome profiling show that gene expression of the transcriprion factors MYB78 and ATAF1 were found to only be changed following a combined stress of heat and drought stress treatment. [MYB78] & [ATAF1]. (Mus musculus) PubMed

 13968.

basic residues in the D1 domain of core that are critical for the formation of infectious extracellular and intracellular particles also play a role in core-NS5A interactions [NS5A][core] (Mus musculus) PubMed

 13969.

The X. laevis CSF-1 and IL-34 displayed strikingly nonoverlapping developmental and tissue-specific gene-expression patterns. CSF-1-derived tadpole macrophages are permissive to FV3. IL-34-administered tadpoles are more resistant. IL34. (Mus musculus) PubMed

 13970.

We concluded that RCN1/OsABCG5 is a salt tolerance factor that acts via Na/K homeostasis, at least partly by regulation of SKC1/OsHKT1;5 in shoots. [RCN1/OsABCG5 ] (Mus musculus) PubMed

 13971.

Data suggest Salmonella Typhimurium strains from salmonella food poisoning/contamination in Italy can be characterized by genetic variations in operon fljA/fljB (phase-1 flagellin repressor/phase 2 flagellin). [fljA; phase-1 flagellin repressor] (Mus musculus) PubMed

 13972.

2,701 RpoD holoenzyme-binding sites were identified by Genomic SELEX screening [RpoD] (Mus musculus) PubMed

 13973.

Data (including data from transgenic mice) suggest HTLV-1 bZIP enhances generation of regulatory T-lymphocytes in HTLV-I infection; this is mediated via up-regulation of Foxp3 expression even though such up-regulation may be transient. [bZIP; HBZ] (Mus musculus) PubMed

 13974.

the polyketide synthase gene pks4 is essential for sexual development and plays a role in regulating fruiting body morphology.[pks4] (Mus musculus) PubMed

 13975.

ggpps727, ggpps191, and ggpps595 are geranylgeranyl diphosphate synthases and contain highly conserved domains. [ggpps727, ggpps191, and ggpps595] (Mus musculus) PubMed

 13976.

Internalization of the constitutively active GPRx (GPR185) is important to release oocyte meiotic arrest. [GPR185] (Mus musculus) PubMed

 13977.

Data indicate that UNC-23 protein interacts with molecular chaperone Hsc70, whose uncoupling from DNJ-13 protein cures the muscular phenotype: [Hsc70] (Mus musculus) PubMed

 13978.

role of tryptophans in OmpX barrel-micelle boundary and protein-micelle association [OmpX] (Mus musculus) PubMed

 13979.

Integrated beet necrotic yellow vein virus P31 specifically induced pathogenesis-related protein 10 transcription, in Nicotiana benthamiana.[P31] (Mus musculus) PubMed

 13980.

lysyl-tRNA synthetase conformational changes upon lysine binding [lysyl-tRNA synthetase] (Mus musculus) PubMed

 13981.

both phosphorylated and non-phosphorylated forms of MapZ are required for proper Z-ring formation and dynamics [FtsZ & MapZ] (Mus musculus) PubMed

 13982.

These findings demonstrate a critical role for natural killer cell intrinsic toll-like receptor-MyD88 signaling in interleukin 12 (IL-12) dependent early IFN-gamma production and innate resistance to T. gondii. (Mus musculus) PubMed

 13983.

Simulation model show that H2AX phosphorylation is biphasic, with initial and succeeding phases associated to DNA-PKcs and ATM respectively. [H2AX]. (Mus musculus) PubMed

 13984.

Data report the crystal structure of C. jejuni CmeC, the outer membrane component of the CmeABC tripartite multidrug efflux system. The structure reveals a possible mechanism for substrate export.[CmeC] (Mus musculus) PubMed

 13985.

The structure of the C-terminal of AIDA-I has the great impact on membrane integration and ligand translocation. [AIDA-I], E.coli strain UT5600. (Mus musculus) PubMed

 13986.

The present results indicated that the miR-252 of Aedes albopictus could regulate the gene expression of DENV-2 E protein and may act asa cellular antiviral regulator in Aedes albopictus.[glycoprotein E] (Mus musculus) PubMed

 13987.

The oxygen limitation that is present in paddy fields and in stagnant rice culture solutions inhibits the phosphate (Pi) overaccumulation toxicity of PHR2-Overexpresses plants by reducing their Pi uptake.[PHR2] (Mus musculus) PubMed

 13988.

These results suggest that Aedae thyrostimulin does indeed participate in ionic and osmotic balance, since it appears to inhibit natriuresis and promote kaliuresis. [thyrostimulin] (Mus musculus) PubMed

 13989.

Homology modeling techniques was used for predicting the secondary structure of SrtA and additionally screened the potential compounds against its microbial and biofilm activity. [srtA] (Mus musculus) PubMed

 13990.

characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1L [Ape1L] (Mus musculus) PubMed

 13991.

OsMYB48-1 functions as a novel MYB-related TF which plays a positive role in drought and salinity tolerance by regulating stress-induced ABA synthesis (Mus musculus) PubMed

 13992.

This study found that sustained swimming (40 days at 0.75 body lengths s(-1)) increased AMPK activity in red and white trout skeletal muscle (3.9- and 2.2-fold, respectively) as well as the expression of AMPK target genes involved in energy use. [AMPK] (Mus musculus) PubMed

 13993.

OsGT47A exhibits functional conservation and is most likely involved in xylan synthesis in rice.[OsGT47A] (Mus musculus) PubMed

 13994.

The transcriptional network of WRKY53 in cereals links oxidative responses to biotic and abiotic stress inputs. [WRKY53] (Mus musculus) PubMed

 13995.

Mis16-Mis18-Mis19-Mis20 CENP-A-recruiting complex, which is functional in the G1-S phase, may be counteracted by the SWI/SNF chromatin-remodeling complex and non-sense-mediated mRNA decay, which may prevent CENP-A deposition at the centromere. (Mus musculus) PubMed

 13996.

These results has provided evidence that mgrA is a global regulator in Staphylococcus aureus, and play an important role in Staphylococcus aureus sepsis, could increase mortality and accelerate the onset and development of sepsis.[mgrA] (Mus musculus) PubMed

 13997.

A membrane protein bond orientations in nanodiscs is obtained by measuring residual dipolar couplings (RDCs) with the outer membrane protein OmpX embedded in nanodiscs using Pf1 phage as an alignment medium. [OmpX] (Mus musculus) PubMed

 13998.

There is no evidence for cryptic speciation for D. citri based on the COI region included in this study.[cytochrome oxidase I] (Mus musculus) PubMed

 13999.

Overexpression of RACK1 (receptor for activated C kinase 1)in maize led to a reduction in symptoms caused by Exserohilum turcicum (Pass.) on maize leaves. [RACK1] (Mus musculus) PubMed

 14000.

FgERG3 and FgERG5 play a crucial role in vegetative differentiation, resistance to fungicides and virulence in F. graminearum. FgErg3 alleles are required for ergosterol biosynthesis in the filamentous fungus F. graminearum.[FgERG3; FgERG5] (Mus musculus) PubMed

 14001.

AcuL could link the glyoxylate cycle to gluconeogenesis by exchanging cytoplasmic succinate for mitochondrial fumarate.[acuL] (Mus musculus) PubMed

 14002.

Only mutations in the OsRac1 Switch I region showed attenuated interactions with OsRbohB in vitro. [OsRac1], [OsRbohB] (Mus musculus) PubMed

 14003.

These results indicate that pgmB plays a role at the juncture of carbohydrate metabolism and virulence.[pgmB] (Mus musculus) PubMed

 14004.

TbNup92 therefore acts as a functional analogue of Mlp/Tpr proteins, and, together with the lamina analogue NUP-1, represents a cohort of novel proteins operating at the nuclear periphery of trypanosomes. [TpNup92] (Mus musculus) PubMed

 14005.

Residues close to the FDP1 diiron site modulate the preference toward O2 or NO. [Flavodiiron protein, Fdp1] (Mus musculus) PubMed

 14006.

Study identified a single prominin homolog, Ci-prom1/2, in the model chordate the ascidian Ciona intestinalis and characterized Ci-prom1/2 expression profile in relation to photoreceptor differentiation during Ciona embryonic development.[Prm1/2] (Mus musculus) PubMed

 14007.

MoRab5B is the Rab5 ortholog; MoRab5A specializes to perform a non-redundant function in endosomal sorting. [MoRab5B].[MoRab5A] (Mus musculus) PubMed

 14008.

These results suggest that the SLT2 MAP kinase is required for Colletotrichum gloeosporioides conidiation, polarized growth, appressorium formation and pathogenicity. (Mus musculus) PubMed

 14009.

findings show OsCYCP1;1 protein was predominantly localized in the nucleus and was ubiquitously expressed throughout the whole plant and during the entire growth period; expression was reduced by phosphate starvation in the roots; this reduction was dependent on PHR2 [OsCYCP1;1] (Mus musculus) PubMed

 14010.

The two related Dicer enzymes from the thermophilic fungus Sporotrichum thermophile have distinct functions in RNA processing. [Dicer-1], [Dicer-2] (Mus musculus) PubMed

 14011.

These data indicate the important role of the phosphorylation in the activity of OmpR on the differential regulation of both ompS1 promoters and its impact on the pathogenesis.[OmpR, ompS1] (Mus musculus) PubMed

 14012.

These results suggest that the mutations, E286R, E302K, and L435R increase the thermostability of Moloney murine leukemia virus reverse transcriptase (MMLV RT)by abolishing its RNase H activity. [MMLV RT] (Mus musculus) PubMed

 14013.

The vesicle-associated membrane protein 2 is a family of seven proteins that regulate post-Golgi vesicular transport via the fusion of vesicles to the target membranes and was found near the ends of the myotubes.(Vesicle-Associated Membrane Proteins 2) (Mus musculus) PubMed

 14014.

[cd7] Pig CD7 cDNA contained an open reading frame (627 bp) encoding 208 amino acids with well conserved motifs involved in signal transduction within cytoplasmic tail among mammalian species (Mus musculus) PubMed

 14015.

The overall configuration of ionizable residues in the OmpC channel that may orient water molecules and the electrostatic profile of the channel play a decisive role in defining the channel properties. [OmpC] (Mus musculus) PubMed

 14016.

subnanometre-resolution structure of detergent-solubilized TmrAB in a nucleotide-free, inward-facing conformation by single-particle electron cryomicroscopy {TmrAB] (Mus musculus) PubMed

 14017.

Data suggest that myocardial HSP70 and HSF1 (heat shock transcription factor 1) can be up-regulated by dietary factors (here, antioxidant taurine as dietary supplement administered to counteract atherogenic diet). [HSP70, 70 kDa heat-shock protein] (Mus musculus) PubMed

 14018.

Taken together, these results suggested that plcA is required for normal vegetative growth, morphogenesis, conidiation, and nuclear division in Aspergillus nidulans.[plcA] (Mus musculus) PubMed

 14019.

In conclusion, our results may provide some clues for further investigation on nitrogen utilization via introducing exogenous GDHs from lower organisms into rice. (Mus musculus) PubMed

 14020.

rGRA5 protein was 100% specific for analysis of toxoplasmosis-negative human sera. Also, rGRA5 was able to detect acute and chronic T. gondii infections (sensitivities of 46.8% and 61.2%, resp.). (Mus musculus) PubMed

 14021.

Primary carrier MetQNI is a high affinity ABC-type transporter specific for l-methionine. a novel secondary methionine uptake system of the NSS (neurotransmitter:sodium symporter) family was identified and named MetP. (MetQN1 and MetP) (Mus musculus) PubMed

 14022.

RNA polymerase alpha-subunit C-terminal domain shows features unique to varepsilon-proteobacteria and binds NikR/DNA complexes [NikR] (Mus musculus) PubMed

 14023.

(c-Kit) The expression of c-Kit was identified in cardiomyocytes from zebrafish embryo hearts. (Mus musculus) PubMed

 14024.

Results show epistatic interaction between dhfr mutations and amplification of GCH1 which confers low level pyrimethamine resistance. [GCH1] [dhfr] (Mus musculus) PubMed

 14025.

Behavior at normal and stress temperatures of the dimeric building blocks of dodecameric small heat shock proteins from wheat (Ta16.9) and pea (Ps18.1) were compared.[Ta16.9] (Mus musculus) PubMed

 14026.

structure and function of PL(pro) [PL(pro)] (Mus musculus) PubMed

 14027.

site-specific S-acylation of influenza virus hemagglutinin [HA] (Mus musculus) PubMed

 14028.

ZmMKK1-overexpressing Arabidopsis enhanced the tolerance to salt and drought stresses.[ZmMKK1] (Mus musculus) PubMed

 14029.

Exposure of A(H1N1)pdm09-infected epithelial cells to HIV-1 viral particles or its gp120 enhanced by 25% the IFITM3 content.[gp120] (Mus musculus) PubMed

 14030.

Results demonstrate that miR-569 is overexpressed in a subset of ovarian and breast cancers and alters cell survival and proliferation through downregulation of TP53INP1 expression. [mir-569]. (Mus musculus) PubMed

 14031.

The paralogous copy F3h-B2 in the B-genome was expressed only in wheat roots and probably is involved in biosynthesis of some uncolored flavonoid compounds unrelated to anthocyanin biosynthesis. (Mus musculus) PubMed

 14032.

these data provide a conclusive rationale for worldwide K13-propeller sequencing to identify and eliminate artemisinin-resistant parasites. [Kelch13] (Mus musculus) PubMed

 14033.

In this study, the humoral immune response to purified recombinant M. avium subsp. paratuberculosis PtpA was investigated using sera from a cohort of sheep infected with M. avium subsp. paratuberculosis and compared with uninfected healthy controls[PtpA] (Mus musculus) PubMed

 14034.

HMG-D and ZmHMGB1 exist in dynamic assemblies in which the basic HMG boxes and linkers associate with their intrinsically disordered, predominantly acidic, tails in a manner analogous to that observed previously for HMGB1.[HMGB1] (Mus musculus) PubMed

 14035.

The effect leptin, orexin-A, and ghrelin on the secretion of luteinizing hormone (LH) and growth hormone by adenohypophyseal explants obtained from normally fed or fasted ewes during the breeding and nonbreeding seasons.[LH] (Mus musculus) PubMed

 14036.

Together, the evidence identifies Sm5HTR as an important neuronal protein and a key component of the motor control apparatus in S. mansoni. (Mus musculus) PubMed

 14037.

Alpha glucosidase specificity increased from the para(p)- to the ortho(o)-hydroxybenzyl alcohol isomer in transglucosylation, whereas such aglycon specificity was not seen in hydrolysis.[alpha glucosidase] (Mus musculus) PubMed

 14038.

Cells infected with viruses containing the VP1 K210E or the 2A L2P substitutions contained the uncleaved VP1-2A protein. The 2A L2P substitution resulted in the VP1/2A junction being highly resistant to cleavage by the 3C protease. (VP1-2A protein) (Mus musculus) PubMed

 14039.

the virulence of the fbsC deletion mutant and its ability to colonize the brain were impaired in murine models of infection. (Mus musculus) PubMed

 14040.

These results suggest that HTLV-1 HBZ contributes to an active BDNF/TrkB autocrine/paracrine signaling loop in HTLV-1-infected T cells that enhances the survival of these cells.[HBZ] (Mus musculus) PubMed

 14041.

The mapped contact domains include the amino-proximal third of 2A (first 50 amino acids) and the central hinge region of L.[2A, L] (Mus musculus) PubMed

 14042.

Selective killing of Kaposi's sarcoma-associated herpesvirus lytically infected cells with a recombinant immunotoxin targeting the viral gpK8.1A envelope glycoprotein. (Mus musculus) PubMed

 14043.

Ribosomal protein L10a plays a role in the regulation of gonadal development in fish.[RpL10A] (Mus musculus) PubMed

 14044.

Recruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparum. (Mus musculus) PubMed

 14045.

This is the first report characterising Cj1564 as a multi-ligand receptor for C. jejuni, we therefore, propose to name this receptor CcmL, Campylobacter chemoreceptor for multiple ligands. (Mus musculus) PubMed

 14046.

GCN5b has a non-redundant and indispensable role in regulating gene expression required during the Toxoplasma lytic cycle. (Mus musculus) PubMed

 14047.

We investigate the slowdown mechanism at the early stage of the reaction using Cel5A-catalyzed phosphate acid-swollen cellulose hydrolysis as a model system. We focus on the effect of enzyme adsorption on the reaction slowdown. (Cel5A) (Mus musculus) PubMed

 14048.

NMIIA and NMIIB perform distinct functions in regulating cell shape during MHB morphogenesis [NM2b] (Mus musculus) PubMed

 14049.

protein lysine methyltransferase Efm5 (Ygr001c) is required for trimethylation of Lys-79 on EF1A [Efm5] (Mus musculus) PubMed

 14050.

High quality long-term CD4+ and CD8+ effector memory populations stimulated by DNA-LACK/MVA-LACK regimen in Leishmania major BALB/c model of infection. (Mus musculus) PubMed

 14051.

These results suggest that human PP6 interacts with and positively regulates the activity of the influenza A virus RNA-dependent RNA polymerase.[RNA-dependent RNA polymerase] (Mus musculus) PubMed

 14052.

CcpE is negative regulator of virulence in S. aureus.[CcpE] (Mus musculus) PubMed

 14053.

Carbon monoxide gas, but not CORM-3, produced inhibition of the nitric oxide detoxification activity of Hmp in vitro.[Hmp] (Mus musculus) PubMed

 14054.

Asp-52 in E. coli GroEL is also involved in the ATP hydrolysis.[GroEL] (Mus musculus) PubMed

 14055.

CrPGK1 might constitute an additional light-modulated Calvin-Benson cycle enzyme with a low activity in the dark and a TRX-dependent activation in the light.[Trx-f] (Mus musculus) PubMed

 14056.

These data indicate an expanded, apicoplast-specific role for Kae1 in the parasite.[Kae1] (Mus musculus) PubMed

 14057.

Efficient catalysis by AlkB depends upon the dynamics of a specific conformational transition, establishing another paradigm for the control of enzyme function by protein dynamics.[AlkB] (Mus musculus) PubMed

 14058.

The PuuP was absolutely necessary for cell growth in the presence of putrescine, because accumulation of putrescine to a high level by PuuP was necessary for utilization of putrescine as an energy source.(PuuP protein, E coli) (Mus musculus) PubMed

 14059.

Thus, MxFIT might be involved in iron uptake and plays an important role in iron deficiency response. [MxFIT] (Mus musculus) PubMed

 14060.

Generated are stabilized alpha-helices of the membrane-proximal external region (SAH-MPER) of gp41. SAH-MPER peptides were remarkably protease resistant and bound to the broadly neutralizing 4E10 and 10E8 antibodies with high affinity. [gp41] (Mus musculus) PubMed

 14061.

Comparison of the X-ray structures of monomeric E coli ClyA and the ClyA protomer in the pore complex reveals one of the largest conformational transitions observed so far in proteins. [ClyA] (Mus musculus) PubMed

 14062.

This homology suggests that fungal proteins involved in either disease susceptibility such as ToxB or resistance such as AvrPiz-t may have a common evolutionary origin. (Mus musculus) PubMed

 14063.

These findings provide novel insights into the slow deactivation mechanism of Kv11.1 channels (Mus musculus) PubMed

 14064.

These data suggest that the AggR-regulated aggregative adherence fimbriae I enhance inflammation and enable the outbreak strain to both adhere to epithelial cells and translocate Stx2a across the intestinal epithelium.[AggR, Stx2a] (Mus musculus) PubMed

 14065.

This study identifies that deletion of 150 residues of Gss1 affects slightly glucose catabolite repression and pexophagy, while maintaining signalling function of Gss1. [Gss1] (Mus musculus) PubMed

 14066.

Here, authors show that Cavally virus 3CL(pro) autoproteolytic cleavage occurs at two N-terminal (N1 and N2) and one C-terminal (C1) processing site(s).[3CL(pro)] (Mus musculus) PubMed

 14067.

FRQ progressively phosphorylated at more than 100 sites; strains with alleles of frq with anomalous phosphorylation display abnormal stability of FRQ that correlates with altered periods or apparent arrhythmicity; study found normal circadian oscillations that reflect allelic state of frq but that persist in the absence of typical degradation of FRQ [FRQ] (Mus musculus) PubMed

 14068.

Collectively, these data suggest that human papillomavirus type 1 E1;E4-mediated inhibition of SRPK1 could affect the functions of host serine-arginine proteins and those of the virus transcription/replication regulator E2.[E1;E4, E2] (Mus musculus) PubMed

 14069.

Authors show that bovine immunodeficiency virus Vif interacts with Cullin 2 (CUL2), ELOB/C, and RBX1, but not with CBF-beta or CUL5, to form a CRL2 E3 ubiquitin ligase and degrade the restrictive bovine APOBEC3 proteins (A3Z2Z3 and A3Z3).[Vif] (Mus musculus) PubMed

 14070.

These data suggest that sapovirus VPg can hijack the cellular translation initiation mechanism by recruiting the eIF4F complex through a direct eIF4E interaction.[VPg] (Mus musculus) PubMed

 14071.

Data dhow that UDP-glucose pyrophosphorylase (ugp; UDP-Glc PPases) exhibited similar catalytic efficiency for glucose-1P and galactose-1P: [UDP-Glc PPases] (Mus musculus) PubMed

 14072.

novel packing arrangement of AcrB in the lipid bilayer membrane (Mus musculus) PubMed

 14073.

Data suggest 3DPol enters nucleus via nuclear localization signal and targets pre-mRNA processing factor 8 (Prp8) to block pre-mRNA splicing/mRNA synthesis, thus shutting off cellular transcription/translation. [3DPol; RNA-dependent RNA polymerase] (Mus musculus) PubMed

 14074.

This study was the first to show positive immunoreactivity for Sall4 in canine seminomas and dysgerminomas and expression of PGP9.5 in canine dysgerminomas. [protein gene product 9.5 ] (Mus musculus) PubMed

 14075.

DWARF3 (D3) assembled into an SCF(D3) complex and associated with DWARF14 (D14) to suppress rice shoot branching (DWARF3). (Mus musculus) PubMed

 14076.

These findings extend the oncogenic potential of HBZ and suggest that viral expression might be involved in the remarkable genetic instability of ATLL cells (HBZ). (Mus musculus) PubMed

 14077.

TaPLDalpha can enhance tolerance to drought and osmotic stress in Arabidopsis and represents a potential candidate gene to enhance stress tolerance in crops. [TaPLDalpha] (Mus musculus) PubMed

 14078.

Peach fruit Glucitol dehydrogenase could be redox regulated in vivo and this would be of relevance to determine carbon assimilation and partitioning in plants accumulating sugar alcohols (Glucitol dehydrogenase). (Mus musculus) PubMed

 14079.

The tls1 mutant phenotypes are caused by impaired boron transport, and boron is essential for inflorescence development in maize.[tls1] (Mus musculus) PubMed

 14080.

StAR1 is likely to be required for cortisol production in the head kidney, and StAR2 is probably involved in estrogen production during early sex differentiation in XX gonads.[StAR1, StAR2] (Mus musculus) PubMed

 14081.

DAT displayed a cocaine-sensitive cation leak current approximately 10-fold larger than the substrate-induced current in Na(+). (Mus musculus) PubMed

 14082.

Data suggest cobT from Sinorhizobium meliloti and homologous enzymes from other bacteria form different ratios of stereoisomeric products from wide range of substrates. [cobT; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase] (Mus musculus) PubMed

 14083.

Data suggest that biocatalysis by UGM involves conformational changes that close the active site; specific active site residues (Asn201, Tyr317, His68) are involved in stabilizing this conformational change. [UGM; UDP-galactopyranose mutase] (Mus musculus) PubMed

 14084.

Data suggest that biocatalysis by UGM involves conformational changes that close the active site; specific active site residues (Asn207, Tyr317, Phe66) are involved in stabilizing this conformational change. [UGM; UDP-galactopyranose mutase] (Mus musculus) PubMed

 14085.

Finally, the scope of TrfA-mediated proteolysis was expanded by identifying TrfA as the adaptor that works with ClpCP to degrade antitoxins in Staphylococcus aureus.[TrfA] (Mus musculus) PubMed

 14086.

In this study, authors show that Nar2 is the main Nar-type respiratory nitrate reductase active in mycelium and could characterize the conditions governing its synthesis. (Mus musculus) PubMed

 14087.

immobilized Sm23 exhibited improved stability compared with soluble Sm23, which can be used for the design of plant cell wall degrading-systems. (Mus musculus) PubMed

 14088.

These results suggest that the gbaAB operon is involved in the regulation of the multicellular aggregation step of Staphylococcus aureus biofilm formation in response to glucose and that this regulation may be mediated through the ica operon.[GbaAB] (Mus musculus) PubMed

 14089.

SAL2 hydrolyzes triglycerides of both short- and long-chain fatty acids and that the released free fatty acids have the potential to cause significant delays in growth, depending on the chemical nature of the free fatty acid.[SAL2] (Mus musculus) PubMed

 14090.

nonconserved middle region of AoLAH has functional importance for regulating the position, movement, and function of Woronin bodies. (Mus musculus) PubMed

 14091.

miR408 has a role in increased drought tolerance in chickpea [miR408] (Mus musculus) PubMed

 14092.

After subsequent species diversification, the SIR2 paralog was apparently lost in the C. lusitaniae lineage (Mus musculus) PubMed

 14093.

KAP6 is involved in the replication and maintenance of kinetoplast DNA. (Mus musculus) PubMed

 14094.

The study presents the structure of Adenylyl Imidodiphosphate-bound BtuCD and the mechanism of ATP-powered vitamin B12 transport by BtuCD-F. [BtuC, BtuD,BtuF] (Mus musculus) PubMed

 14095.

ProQ functions as a novel translational regulator, and its cellular role extends beyond its effects on proline uptake by ProP. [ProQ] (Mus musculus) PubMed

 14096.

Site-directed mutagenesis with E. coli isocitrate dehydrogenase shows that the lysine is essential to catalysis, even though it is not found in highly conserved active sites of related enzymes catalyzing homologous reactions [IDH] (Mus musculus) PubMed

 14097.

Evidence for interaction of NblA with intact phycobilisomes, assigning to NblA a role in the supra-complex disassembly. The role of NblA as a degradation tag is demonstrated based on the rapid degradation of the fusion protein NblA::GFP. [NblA] (Mus musculus) PubMed

 14098.

OsABCB14 plays a role as an auxin influx transporter involved in Fe homeostasis. [OsABCB14] (Mus musculus) PubMed

 14099.

Using molecular docking analysis, dynamic simulation and mutational analysis, the structure and function of AzgA has been elucidated. (Mus musculus) PubMed

 14100.

phosphorylation of Atg9 by Atg1 is required for phagophore elongation.[Atg9, Atg1] (Mus musculus) PubMed

 14101.

Taken together, these data indicate that AdhE increases Ply under the ethanol stress condition, thus potentiating pneumococcal virulence.[AdhE] (Mus musculus) PubMed

 14102.

The expression of MUC2 increased with age and reached the highest level at 47 days of age.[MUC2] (Mus musculus) PubMed

 14103.

GlxR represses the transcription of all three gen operons and then contributes to the synchronization of their expression for 3-hydroxybenzoate and gentisate catabolism in collaboration with the specific regulator GenR. [GlxR] (Mus musculus) PubMed

 14104.

SiREM6 is a target gene of SiARDP and plays a critical role in high salt stress tolerance [REM6][ARDP] (Mus musculus) PubMed

 14105.

covS gene is a genomic mutagenic target that gives GAS enhanced virulence [covS] (Mus musculus) PubMed

 14106.

study identified a novel telomere protein, T. brucei TRF-Interacting Factor 2 (TbTIF2), as a functional homolog of mammalian TIN2; TbTIF2 plays an important role in VSG switching regulation and is important for subtelomere integrity and stability [TIF2] (Mus musculus) PubMed

 14107.

Results demonstrate that Mac1 and Mac2 are targeted to peroxisomes, while other enzymes involved in mannosylerythritol lipids production reside in different compartments. [Mac1] & [Mac2]. (Mus musculus) PubMed

 14108.

The loss-of-function study identifies important roles for LdCyP40 in the development of infectious parasites in vitro and intracellular parasite survival independent of its phosphorylation status. (Mus musculus) PubMed

 14109.

MdSBP1 is probably the only factor responsible for recognition with S-RNase, while not a component of the SCF complex, and an SCF complex containing MdSSK1 is required for mediating the ubiquitination of S-RNase.[SBP1] (Mus musculus) PubMed

 14110.

FIB encodes a tryptophan aminotrasferase gene and loss of function results in small leaves with large lamina joint angles, abnormal vascular development, small panicles, abnormal organ identity and defects in root development. [FIB] (Mus musculus) PubMed

 14111.

Down-regulation of miR-129-5p inhibits growth and induces apoptosis in laryngeal squamous cell carcinoma by targeting APC. [miR-129-5p] (Mus musculus) PubMed

 14112.

Cortexillin III may be a negative regulator of cell growth, cytokinesis, pinocytosis, and phagocytosis, as all are enhanced in cortexillin III-null cells. [cortexillin III] (Mus musculus) PubMed

 14113.

These results demonstrate that Aap contributes to Staphylococcus epidermidis infection, which may in part be due to A domain-mediated attachment to abiotic surfaces. (Mus musculus) PubMed

 14114.

OsSAP1 plays a key role in basal resistance against pathogen infection. [OsSAP1] (Mus musculus) PubMed

 14115.

rall, our data suggests that sucrose synthesis via OsSPS1 is essential in pollen germination in rice. [OsSPS1] (Mus musculus) PubMed

 14116.

wxcB is involved in virulence, motility, detergent tolerance, and biofilm formation in Xanthomonas campestris pv. vesicatoria strain 85-10. [wxcB] (Mus musculus) PubMed

 14117.

PmvE possesses an N-acetyltransferase activity toward polyamine substrates and contributes to the virulence of Enterococcus faecalis, likely through its involvement in the polyamine metabolism. (Mus musculus) PubMed

 14118.

In this study, authors identified a two-component regulatory system GrvRS as the main regulator of ace expression under these stress conditions.[GrvRS, ace] (Mus musculus) PubMed

 14119.

OG1RF_11582, which encodes a 6-phosphogluconolactonase was designated pglA, and its deletion impaired both pathogenesis and gut persistence in Manduca sexta. (Mus musculus) PubMed

 14120.

In this study, we isolated OsLCT1 cDNA from Kasalath, a model indica cultivar and conducted cation transport activity assays in yeast and mRNA expression analysis in plants [OsLCT1] (Mus musculus) PubMed

 14121.

MOP1 regulates the higher-order chromatin organization where loss of MOP1 activity at a subset of loci triggers a broader cascade of transcriptional consequences and genome-wide changes in chromatin structure.[NEW ENTRY] (Mus musculus) PubMed

 14122.

characterization of the Na+/H+-antiporter NhaA from Salmonella Typhimurium [NhaA] (Mus musculus) PubMed

 14123.

The fungal virulence factor laccase was also implicated in plant pathogenesis, as a cryptococcal lac1Delta strain was less virulent than wild-type fungi and was unable to colonize seedlings. [lac1, strain ATCC 208821] (Mus musculus) PubMed

 14124.

changes in the expression of downstream regulators of skeletal differentiation, like barx1 and gdf5, is one mechanism by which head skeletal element number and articulation are altered during evolution. [barx1] (Mus musculus) PubMed

 14125.

A second citrate synthase, SbnG, has been described in Staphylococcus aureus H267 (Newman). (Mus musculus) PubMed

 14126.

Blockade of NaV1.8 channels suppresses the effects of vagus nerve stimulation on cardiac conduction and atrial fibrillation inducibility [nav1.8] (Mus musculus) PubMed

 14127.

results indicated that gene sypQ is associated with poly-N-acetylglucosamine biosynthesis and PNAG is involved in pathogen colonization [sypQ] (Mus musculus) PubMed

 14128.

This study used the recently reported medium resolution cryo-EM density of the yeast 80S IC and high resolution crystal structures of eIF5B from C. thermophilum to propose a new model for the interactions between eIF5B domain IV and the Met-tRNAi in the context of the ribosome. [eIFB5] (Mus musculus) PubMed

 14129.

A crystal structure of RabX3, a tandem GTPase from Entamoeba histolytica, has been determined. (Mus musculus) PubMed

 14130.

The crystal structure of the catalytic domain of a thermophilic beta-1,3-1,4-glucanase has been determined. (Mus musculus) PubMed

 14131.

p38 MAPK regulates p47phox gene expression in fish.[p38 MAPK] (Mus musculus) PubMed

 14132.

A single point mutation in cpsE caused phenotypic changes in growth, adherence to epithelial cells and transformability.[cpsE] (Mus musculus) PubMed

 14133.

A new interaction between Rad54 and the replicative DNA clamp, proliferating cell nuclear antigen (PCNA), was identified.[PCNA, Rad54] (Mus musculus) PubMed

 14134.

These findings allow the authors to define a new operon, msaABCR, that regulates fundamental phenotypes in S. aureus such as biofilm development and virulence.[msaABCR] (Mus musculus) PubMed

 14135.

The results demonstrated for the first time that Rho and RNase E/G, play a central role in the riboswitch-mediated gene expression control (Rho, RNase G and RNase E). (Mus musculus) PubMed

 14136.

Thus the raft-targeting signal of HA encompasses not only hydrophobic, but also aromatic and positively charged, residues. We speculate that binding to cholesterol might facilitate intracellular transport of HA and association with rafts. (Mus musculus) PubMed

 14137.

PLR-1 is a putative E3 ubiquitin ligase that controls cell polarity and axonal extensions in C. elegans [PLR-1] (Mus musculus) PubMed

 14138.

Authors demonstrate that the nucleotide binding motifs of both proteins CstE and CstP are essential for their function in transformation of Campylobacter jejuni and and interaction of CtsP with CtsX, an integral membrane protein.[CstE, CstP, CstX] (Mus musculus) PubMed

 14139.

CagX directly interacts with CagT through the C-terminal domain of CagX [CagX; CagT] (Mus musculus) PubMed

 14140.

(CREB2)Overexpressing CREB2 in the postsynaptic neuron contributes to long-term facilitation at the synapse. (Mus musculus) PubMed

 14141.

A new anthocyanin MYB-like protein, Beta vulgaris MYB1, regulates the betalain pathway. It is coded at the Y locus and is expressed differently in Y and y beets. It does not interact with bHLH members of heterologous anthocyanin MBW conplexed. BvMYB1. (Mus musculus) PubMed

 14142.

(Adenosine A2B receptor)Specific regions of the adenosine A2B receptor were identified that are essential for its activation and inactivation. (Mus musculus) PubMed

 14143.

AgKir1 encodes a functional, barium-sensitive Kir channel. (Mus musculus) PubMed

 14144.

transmembrane helix 2 has a key role in light-induced channel opening and closing in channelrhodopsin-2 [ChR2] (Mus musculus) PubMed

 14145.

These results suggest that GKN1 might be a target to inhibit the effects from H.pylori CagA. (Mus musculus) PubMed

 14146.

Deletion of RSR1 in cells lacking the Ras GTPase Ras2 caused lethality.[Ras2, Rsr1] (Mus musculus) PubMed

 14147.

The crystal structure of the complex of CbpM with the J-domain of CbpA, is reported.[CbpA, CbpM] (Mus musculus) PubMed

 14148.

It demonstrates that one of the multiple Mmi1 foci in mitotic cells localizes to the the sme2 locus.(Mmi1 protein, S pombe) (Mus musculus) PubMed

 14149.

These results provide the first evidence for a hitherto unknown function of the VP22 tegument protein in herpesviral reprogramming of the cell cycle of the host cell.[VP22] (Mus musculus) PubMed

 14150.

PUF2 is a cytoplasmic protein that is essential for normal growth of bloodstream-form trypanosome. [PUF2] (Mus musculus) PubMed

 14151.

Pbx1 and Pbx2 act in remodeling the cell wall to maintain normal cell morphology and precursor availability for other glycan synthetic processes. [Pbx1 and Pbx2] (Mus musculus) PubMed

 14152.

It constructed a three-dimensional model of UreA which, combined with site-directed and classical random mutagenesis, led to the identification of amino acids important for UreA function. (Mus musculus) PubMed

 14153.

Thus, the coiled-coil domain of WbdD functions as a molecular ruler that, along with WbdA:WbdD stoichiometry, controls the chain length of a model bacterial polysaccharide.[WbdA, WbdD] (Mus musculus) PubMed

 14154.

In summary, authors have determined that GtfC is important for the glycosylation of Srr2 and identified a conserved loop region that is crucial for acceptor substrate binding from GtfC homologs in streptococci.[GtfC, Srr2] (Mus musculus) PubMed

 14155.

The results demonstrate that AdcR senses the zinc availability and responds by regulating the expression of genes involved in zinc homeostasis, metabolism and virulence (AdcR). (Mus musculus) PubMed

 14156.

SdhA encoding succinate dehydrogenase subunit A plays a role in cysR-mediated sulfur metabolism. [sdhA, cycR] (Mus musculus) PubMed

 14157.

Accordingly, deletion of rshA resulted in hyperproduction of riboflavin and affected expression of Zn-responsive genes, possibly through intracellular Zn overload, indicating new physiological roles of sigma(H).[rshA] (Mus musculus) PubMed

 14158.

CydX may function by positioning and stabilizing the prosthetic hemes, especially heme d in the CydA-CydB complex although a role of participating in catalytic reaction is not excluded. (Mus musculus) PubMed

 14159.

The results show that RAD51B is indispensable for DNA damage repair and homologous recombination in somatic cells and that this role is independent of the SRS2 anti-recombination helicase(RAD51B). (Mus musculus) PubMed

 14160.

Study shows that sialostatin L2 attenuates phosphorylation of STATs in spleen dendritic cells upon addition of recombinant IFN-beta. LPS-stimulated dendritic cells release IFN-beta which in turn leads to the induction of IFN-stimulated genes through JAK/STAT pathway activation. [sialostatin L2] (Mus musculus) PubMed

 14161.

LAH-3, a transcriptional factor is involved in osmotic regulation. [LAH-3] (Mus musculus) PubMed

 14162.

Phylogenetic analyses strongly suggest that G2/M arrest/SLX4 interactions are ancestral activities of primate lentiviral Vpr proteins and that the ability to dysregulate the Fanconi anemia DNA repair pathway is an essential function of Vpr in vivo.[Vpr] (Mus musculus) PubMed

 14163.

These results suggest that a small unstructured region in the ToxT N-terminal domain is involved in multiple aspects of virulence gene regulation and response to human host signals. (Mus musculus) PubMed

 14164.

Xfp2 is inhibited by ATP, phosphoenolpyruvate, and oxaloacetic acid and activated by AMP.[Xfp2] (Mus musculus) PubMed

 14165.

The data show that dUTPase strongly binds to the Stl repressor protein in the absence of substrate and this complex disrupts the capability of Stl binding to its cognate DNA element (Stl). (Mus musculus) PubMed

 14166.

This acylamidase, as a result of its unique substrate specificity, can hydrolyse N-substituted amides (4'-nitroacetanilide, N-isopropylacrylamide, N'N-dimethylaminopropylacrylamide). (Mus musculus) PubMed

 14167.

Combinations of hsm3 and hsm6 mutations with mutations in other genes of the RAD52 epistatic group did not provide a spontaneous mutation rate decrease. (Mus musculus) PubMed

 14168.

SopB and SigE are assembled in dynamic homohexameric-ring-shaped structures with an internal tunnel. [SopB, SigE] (Mus musculus) PubMed

 14169.

Cpl1 is a specific surface protein of C. neoformans var. neoformans.[Cpl1] (Mus musculus) PubMed

 14170.

Loss of CPS-1 results in a cell wall defect that affects all stages of the Neurospora crassa life cycle, including vegetative growth, protoperithecia (female mating structure) development, and conidia (asexual spore) development.[CPS-1] (Mus musculus) PubMed

 14171.

Vaccinia virus C16 reprogrammes cellular energy metabolism towards increased synthesis of the metabolic precursors utilized during viral replication via the stabilization of HIF-1alpha. (Mus musculus) PubMed

 14172.

HP119 protein is a DNA-binding protein and plays an important role in Helicobacter pylori stress tolerance and survival in the host.[HP119] (Mus musculus) PubMed

 14173.

These results describe both the location of ZmElc expression in maize and a new activity associated with an Elc: support of potyvirus accumulation.[ZmELC] (Mus musculus) PubMed

 14174.

These results in P. patens demonstrate the morphogenetic importance of the DEK1 protein in the control of oriented cell divisions.[DEK1] (Mus musculus) PubMed

 14175.

BmPLLG: is involved in pheromone biosynthesis activating neuropeptide-induced sex pheromone biosynthesis and release (Mus musculus) PubMed

 14176.

This study showed that phloridzin improved plasma lipoprotein lipase activity via a decrease of ANGPTL4 mRNA expression and an increase of AMP-activated protein kinase (AMPK) phosphorylation.[AMPK] (Mus musculus) PubMed

 14177.

characterization of a beta-hydroxyacid dehydrogenase from Geobacter sulfurreducens and Geobacter metallireducens [beta-hydroxyacid dehydrogenase] (Mus musculus) PubMed

 14178.

The study highlight the identification of unique epitopes of PfHRP2 and PfLDH, and the generated antibodies against these antigens were used for quantitative estimation of these two antigens using sandwich ELISA (Mus musculus) PubMed

 14179.

Taken together, our data suggest that the two protozoa p23 isoforms act similarly when regulating Hsp90 function. (Mus musculus) PubMed

 14180.

It showed that arginine stabilizes the NAGK hexamer and stimulates PII - NAGK interaction. (Mus musculus) PubMed

 14181.

Gln91 and Arg92 of TsiV3 are located in the centre of the interface and are important for recognition of VgrG3[VgrG3,TsiV3] (Mus musculus) PubMed

 14182.

A long N-terminal helix is an important feature for the stability of this fungal (R)-selective amine transaminase, but is missing in branched-chain amino-acid aminotransferases and D-amino-acid aminotransferases. [(R)-selective amine transaminase] (Mus musculus) PubMed

 14183.

E270 of 3-isopropylmalate dehydrogenase seems to position K(+) into close proximity of the nicotinamide ring of NAD(+)[3-Isopropylmalate Dehydrogenase] (Mus musculus) PubMed

 14184.

OsXXT1 is important in maintaining cell wall structure and tensile strength (OsXXT1. (Mus musculus) PubMed

 14185.

ArsH may be involved in coordinating oxidative stress response generated by arsenic in Synechocystis sp. PCC 6803. [ArsH] (Mus musculus) PubMed

 14186.

enzyme activity and thermostability of AmyI-1 [AmyI-1] (Mus musculus) PubMed

 14187.

a Medicago truncatula gene, SymCRK, which encodes a cysteine-rich receptor-like kinase that is required for rhizobia maintenance within the plant cells, was identified.[symCRK] (Mus musculus) PubMed

 14188.

Expression of the ler gene, the LEE-encoded master regulator, is affected at a post-transcription step by fur mutation. [ler] (Mus musculus) PubMed

 14189.

Authors showed that glycosylation in Cryptococcus by Pmt2 plays important roles in diazobenzoic acid B staining, controlling cell size, resistance to high temperature and osmolarity, capsule formation, sexual reproduction, and virulence.[Pmt2] (Mus musculus) PubMed

 14190.

All three proteins in the FtsA/HookA/FhipA complex are important for dynein-mediated early endosome movement. [FhipA/ANIA_10801] (Mus musculus) PubMed

 14191.

A cyclin-like protein from Aspergillus nidulans, ClgA, was identified and its cyclin-like subunit shares 28.3% identity to Saccharomyces cerevisiae Clg1.[ClgA] (Mus musculus) PubMed

 14192.

Toxoplasma gondii tachyzoites possess regulatory volume decrease capability during hypo-osmotic stress and this ability is impaired in TgVP1 null mutants implicating TgVP1 in osmoregulation.[TgVP1] (Mus musculus) PubMed

 14193.

Authors conclude that a mutation in the CAP10 gene results in a pleiotropic phenotype with effects on different cellular processes affecting, amongst others, cell size, expression of virulence factors and size of extracellular vesicles.[CAP10] (Mus musculus) PubMed

 14194.

CrNZF1 is proposed to regulate NIT2 polyadenylation and thus nitrate signalling and nitrate-dependent growth in the alga.[CrNZF1] (Mus musculus) PubMed

 14195.

CtpA(-) mutant strain is attenuated for virulence in a mouse model.[CtpA] (Mus musculus) PubMed

 14196.

Tthe cold-responsive MaNAC1 may be involved in cold tolerance of banana fruits through its interaction with ICE1-CBF cold signalling pathway.[MaNAC1, MaICE1, MaCBF1] (Mus musculus) PubMed

 14197.

sll0939 is directly involved in the low pH tolerance of Synechocystis sp. PCC 6803 and that slr0967 may be essential for the induction of acid stress-responsive genes. [slr0967, sll0939] (Mus musculus) PubMed

 14198.

These results indicate that the constitutive expression of the rice Xa21 gene in banana results in enhanced resistance against Xanthomonas campestris pv. musacearum.[Xa21] (Mus musculus) PubMed

 14199.

This result validated that resistance to Ug99 in Webster and Gabo 56 is conferred by the same gene: Sr9h.[Sr9h] (Mus musculus) PubMed

 14200.

we carried out a crystal structure analysis at 1.6 A resolution of the (R)-amine transaminase from Aspergillus fumigatus with the bound inhibitor gabaculine. (Mus musculus) PubMed

 14201.

These data demonstrate the role of Tran in regulation in S. suis serotype 2, that is affect bacterial virulence by influencing bacterial metabolism and stress tolerance of external environment.[Tran] (Mus musculus) PubMed

 14202.

in Drosophila and Caenorhabditis elegans, overexpression of diacylglycerol lipase (DAGL/inaE/dagl-1) or knockdown of diacylglycerol kinase (DGK/rdgA/dgk-5) extends lifespan and enhances response to oxidative stress.[Tor, DAGL] (Mus musculus) PubMed

 14203.

IscU retains a structured conformation in the Fe-S cluster assembly complex [IscU] (Mus musculus) PubMed

 14204.

The inoculation of the plant growth-promoting rhizobacteria could potentially result in inducing the expression of the salt stress-related RAB18 plant gene under varying degrees of salinity stress.[RAB18] (Mus musculus) PubMed

 14205.

Authors have characterised the role of Tem1 in Candida albicans, and demonstrate that it is essential for mitotic exit and cytokinesis, and that this essential function is signalled through the kinase Cdc15.[Tem1] (Mus musculus) PubMed

 14206.

In contrast, the levels of 4-thiouridine-labelled Pol I transcripts were increased by two- to sixfold, suggesting that H1 histone preferentially blocks transcription at RNA polymerase I loci.[H1, RNA polymerase I] (Mus musculus) PubMed

 14207.

Authors verify the ability of HSF1 to activate transcription using a modified yeast one-hybrid system, and we show that it can bind to the heat shock binding element (HSE) consensus DNA sequence.[HSF1 (Mus musculus) PubMed

 14208.

crystal structures of TSPO and a mutant that mimics the human Ala(147)-->Thr(147) polymorphism associated with psychiatric disorders and reduced pregnenolone production; the crystal structures show the same tightly interacting dimer and provide insights into the physiological role of TSPO [TSPO] (Mus musculus) PubMed

 14209.

The telomere duplex DNA-binding factor, TbTRF, also plays a critical role in variant surface glycoprotein (VSG) switching regulation, as a transient depletion of TbTRF leads to significantly more VSG switching events (TbTRF). (Mus musculus) PubMed

 14210.

Nuclear localization of porcine circovirus type 1 viral protein 3 (VP3) is necessary neither for induction of apoptosis nor for transformed cell selectivity, and suggest a mechanism of action distinct from that of apoptin.[VP3] (Mus musculus) PubMed

 14211.

Tsdaf-21 and the corresponding protein are ubiquitously and strongly expressed in all stages. [Tsdaf-21] (Mus musculus) PubMed

 14212.

MEKK-3 may function as an important nutrient sensor and signalling component within the organism that controls metabolism.[MEKK-3] (Mus musculus) PubMed

 14213.

The transmembrane and cytoplasmic domains of PBP2b and PBP2x are also involved in interactions with components of the septal and peripheral peptidoglycan synthesis machineries. [PBP2b, PBP2x] (Mus musculus) PubMed

 14214.

Authors demonstrated that swine importin alpha1 interacts with the M1 protein and transports it to the nucleus.[M1] (Mus musculus) PubMed

 14215.

These results suggest that the molecular mechanism of substrate inhibition of BetB is associated with the nonproductive binding of betaine aldehyde.[BetB] (Mus musculus) PubMed

 14216.

All these findings revealed a significant contribution of gdpP and its substrate (c-di-AMP) to the biology and virulence of Streptococcus suis serotype 2.[gdpP] (Mus musculus) PubMed

 14217.

These data implicate differential roles of N-glycosylation modifications in contributing to the stability of specific functional regions of CBH1.[CBH1] (Mus musculus) PubMed

 14218.

The full-length protein OrysaEULD1A as well as its individual domains OrysaEULD1A domain 1 and 2 were expressed in Pichia pastoris. (Mus musculus) PubMed

 14219.

These results indicated the important role of CAT8 in regulating the glucose metabolism of Pichia guilliermondii and that the regulation was partially mediated by repressing HAP4.[CAT8] (Mus musculus) PubMed

 14220.

The cellular localization and function of CoPK12 are regulated by protein N-myristoylation and limited proteolysis.(CoPK12) (Mus musculus) PubMed

 14221.

PswP is required for the production of three diffusible althiomycin, serrawettin W2 and siderophore. (Mus musculus) PubMed

 14222.

The study identified a highly conserved tyrosine residue, Y229, as a major amino acid determinant for maximal activation of transcription by AgrA and provides novel insights into structure-function relationships in S. aureus AgrA (AgrA). (Mus musculus) PubMed

 14223.

GS-1, is required for cell wall biosynthesis during macroconidia development. [ags1] (Mus musculus) PubMed

 14224.

The results showed that the interface between the BV gD and nectin-1 molecule is not geometrically complementary.[gD] (Mus musculus) PubMed

 14225.

There is a stringent but incomplete developmental requirement for proper migration and positioning of fungal nuclei mediated by MoAND1 during asexual reproduction and pre-penetration phase of fungal pathogenesis.[AND1] (Mus musculus) PubMed

 14226.

Cyt b-559 optimises electron transfer on the acceptor side of PSII and plays physiologically important roles in the assembly, repair and maintenance of the complex. [Cyt b-559] (Mus musculus) PubMed

 14227.

The honeybee TET (AmTET) catalytic domain has dioxygenase activity and converts 5-methylcytosine to 5-hydroxymethylcytosine. [TET] (Mus musculus) PubMed

 14228.

By applying comparative genomics analyses, 19 polymorphic sequence-tagged site markers were developed and integrated into the Pm41 genetic linkage map.[Pm41] (Mus musculus) PubMed

 14229.

These results provide direct evidence for a key role of SNARE proteins Sso2p and Sec9p in vesicle-mediated polarized hyphal growth and enzyme secretion of Candida albicans.[Sso2p and Sec9p] (Mus musculus) PubMed

 14230.

The green/red pod color in cacao is likely regulated by the MYB transcription factor TcMYB113. [MYB113] (Mus musculus) PubMed

 14231.

The flagellar genes Fla2 is controlled by the CckA and is repressed by organic acids and the expression of Fla1. [cckA] (Mus musculus) PubMed

 14232.

VvMYBPAR specifically activates proanthocyanidin biosynthetic genes in grapevine (VvMYBPAR). (Mus musculus) PubMed

 14233.

4-O-beta-D-mannosyl-D-glucose phosphorylase from Rhodothermus marinus [MGP] (Mus musculus) PubMed

 14234.

The interaction between OsCPK8 and two of these proteins (ARF-GEF and peptidyl prolyl isomerase) was confirmed in rice cells by means of BiFC technology (Mus musculus) PubMed

 14235.

MtlA is required for conidia formation, cell wall stress tolerance, and cell wall integrity in Aspergillus nidulans [MtlA] (Mus musculus) PubMed

 14236.

Our results collectively showed that VP12 is involved in host cell binding via interaction with adenine nucleotide translocase (Mus musculus) PubMed

 14237.

Authors propose a regulation model whereby the bile-mediated activation of the acrAB and tolC multidrug efflux genes occurs mainly through the transcriptional derepression of the ramA activator gene.[ramA] (Mus musculus) PubMed

 14238.

Authors show that the largely nuclear P-protein isoform P3 can localize to nucleoli and forms specific interactions with nucleolin. (Mus musculus) PubMed

 14239.

This finding suggests that M2 proton channel activity may play a wider role in preserving HA fusion competence among a variety of HA subtypes, including HA proteins from emerging strains that may have reduced HA stability.[HA, M2] (Mus musculus) PubMed

 14240.

These findings indicate that P25 is the main potato virus X determinant involved in eliciting a systemic hypersensitive response-like response in potato virus X-associated synergisms.[P25] (Mus musculus) PubMed

 14241.

These results indicate that DNA binding causes a moderate shift in the reduction potential of SoxR. [SoxR] (Mus musculus) PubMed

 14242.

PfHP1 is centrally involved in clonally variant gene expression and sexual differentiation in P. falciparum. [PfHP1] (Mus musculus) PubMed

 14243.

SHR protein plays a role in the development of vascular tissue and kranz anatomy in maize leaves [SHR] (Mus musculus) PubMed

 14244.

The Streptococcus mutans irvA gene encodes a trans-acting riboregulatory mRNA. [irvA] (Mus musculus) PubMed

 14245.

Hemolysin LukGH forms heterodimers in solution and differs from other two-component leukocidins that interact only upon cell contact. [LukGH] (Mus musculus) PubMed

 14246.

The most frequent clarithromycin-resistance 23S rRNA genotype in H. pylori-positive gastric biopsy specimens was A2143G, followed by A2142G (23S rRNA). (Mus musculus) PubMed

 14247.

the mechanism of OsSERK2-meditated regulation of rice XA21, XA3, and FLS2 [SERK2][XA21][XA3] (Mus musculus) PubMed

 14248.

[lpfA, no strain specified]mastitis phenotype, phylogroup and presence of lpfA were associated with the ability to invade cultured bovine mammary epithelial cells (Mus musculus) PubMed

 14249.

novel chloroplast-localized pentatricopeptide repeat protein involved in splicing affects chloroplast development and abiotic stress response in rice [wsl] (Mus musculus) PubMed

 14250.

NEKL-2 and NEKL-3 were specifically required within the large epidermal syncytium, hyp7, to facilitate molting.[NEKL-2, NEKL-3] (Mus musculus) PubMed

 14251.

By high-resolution linkage analysis in 141 recombination events, DNL1 was narrowed to a 62.39kb region of InDel markers ID12M28 and HF43.[DNL1] (Mus musculus) PubMed

 14252.

Binding of tRNA to MiaE induces a protein conformational change. [MiaE] (Mus musculus) PubMed

 14253.

These results suggest that amebic PI3K and PKC activation may play an important role in caspase-independent cell death in Entamoeba-induced apoptosis.[PKC] (Mus musculus) PubMed

 14254.

Macromolecular crowding increases Km of malate dehydrogenase for oxaloacetate reduction. [malate dehydrogenase] (Mus musculus) PubMed

 14255.

TIGAR/C12orf5 regulates proximal kidney tubule glycolysis and apoptotic cell death in the setting of severe ischemia-reperfusion injury. (Mus musculus) PubMed

 14256.

Authors find that the number of N-glycosylated residues in glycosylated Pr80 inversely correlates with the sensitivity of a gammaretrovirus to deamination by mouse APOBEC3.[Pr80] (Mus musculus) PubMed

 14257.

Study identified PAX5 as a novel EBER2-interacting protein, prompted by the observation that this transcription factor and the viral noncoding RNA co-localize at the tandem repeats, interaction appears to be indirect, based on the negative results of electrophoretic mobility shift assays and UV crosslinking experiments. [EBER2] (Mus musculus) PubMed

 14258.

In summary, our data demonstrate glycosylation heterogeneity of Srr1, characterize a new protein modification, and identify six glycosylation sites located in the N-terminal region of the protein [Srr1] (Mus musculus) PubMed

 14259.

A new invertase was isolated from from A. niger GH1. The invertase gene had a length of 1770 bp without introns and encodes a protein of 589 amino acids. invGS (Mus musculus) PubMed

 14260.

The crystal structure of the lysine biosynthetic enzyme LysZ was determined in a complex with LysW. [LysZ], [LysW] (Mus musculus) PubMed

 14261.

Substrate transport by Vibrio SGLT involves two substrate sites. [SGLT] (Mus musculus) PubMed

 14262.

The binding involved the 106-to-131 domain, corresponding to the dimerization domain of rabies virus phosphoprotein P and the C-terminal domain of FAK containing the proline-rich domains PRR2 and PRR3.[phosphoprotein P] (Mus musculus) PubMed

 14263.

Data prove the functional importance of emerin as an nuclear egress complex component, associated with pUL50, pUL53, pUL97, p32/gC1qR, and further regulatory proteins. [emerin] (Mus musculus) PubMed

 14264.

Although human rhinovirus 3A protein was previously shown to interact with ACBD3, these data suggest that PI4KIIIbeta recruitment occurred independently of both GBF1 and ACBD3. (Mus musculus) PubMed

 14265.

Although the in vitro data do not support a direct role for GSTE4 in metabolism, they do support a role for this enzyme in insecticide sequestration.[GSTE4] (Mus musculus) PubMed

 14266.

The null lys4Delta mutant exhibited lysine auxotrophy in minimal medium but was able to grow in the presence of l-Lys and alpha-aminoadipate, an intermediate of the alpha-aminoadipate pathway, at millimolar concentrations.[LYS4] (Mus musculus) PubMed

 14267.

CagA and F-BAR domains share binding specificity for phosphatidylserine and phosphoinositides.[CagA] (Mus musculus) PubMed

 14268.

Here are describe two previously unstudied p21-activated kinases isoforms, PAK4 and PAK5, as highly specific effectors of RacC. [PAK4, PAK5, RacC] (Mus musculus) PubMed

 14269.

[ORF3] the ORF3 protein of DuCV might play an important role in viral pathogenesis via its apoptotic activity (Mus musculus) PubMed

 14270.

results establish a new function for Cas9 in the genesis of prokaryotic immunological memory [Cas9] (Mus musculus) PubMed

 14271.

Authors propose that nucleoprotein oligomerization in infected cells is regulated by reversible phosphorylation.[nucleoprotein] (Mus musculus) PubMed

 14272.

Endo-beta-1,4-xylanase (XynB) exhibited resistance to many metal ions and low pH values.[XynB] (Mus musculus) PubMed

 14273.

The Sup35 prion domain has the folded in-register parallel beta-sheet architecture and suggests common locations of the folds.[Sup35p] (Mus musculus) PubMed

 14274.

Ectopic expression of ICP6, but not RHIM mutant ICP6, directly activated RIP3/MLKL-mediated necrosis.[ICP6] (Mus musculus) PubMed

 14275.

Kat1 is a highly regulated transposase-derived endonuclease vital for sexual differentiation.[Kat1] (Mus musculus) PubMed

 14276.

CHT7 likely is a repressor of cellular quiescence and provides a possible target for the engineering of high-biomass/high-triacylglycerol microalgae. (Mus musculus) PubMed

 14277.

Taken together, these results indicate that Nsp9 binding partner ANXA2 is beneficial for porcine reproductive and respiratory syndrome virus replication. (Mus musculus) PubMed

 14278.

The solution structures of UNC-60A and UNC-60B proteins were determined and characterized their backbone dynamics.[UNC-60A, UNC-60B] (Mus musculus) PubMed

 14279.

These data support a model in which unfolded outer membrane protein after docking with its C-terminus penetrates into the transmembrane beta-barrel of the Omp85 protein and augments its beta-sheet at the first strand.[TtOmp85] (Mus musculus) PubMed

 14280.

This suggests a function of LacR as a transcriptional repressor of lac operon I, which encodes enzymes involved in the phosphorylated tagatose pathway in the absence of lactose or galactose.[LacR] (Mus musculus) PubMed

 14281.

the minimal mechanism for recognition and excision of 1,N(6)-ethenoadenine (epsilonA) by AlkA, was investigated.[AlkA] (Mus musculus) PubMed

 14282.

These new findings suggest that Sinorhizobium meliloti LsrB is associated with lipopolysaccharide biosynthesis, which is required for symbiotic nitrogen fixation on some ecotypes of alfalfa plants. (Mus musculus) PubMed

 14283.

The Aspergillus fumigatus AcuK and AcuM transcription factors have divergent targets during growth in vitro versus invasive disease. [AcuK], [AcuM] (Mus musculus) PubMed

 14284.

The endoplasmic reticulum adaptor protein ERAdP initiates NK cell activation via the Ubc13-mediated NF-kappaB pathway. (Mus musculus) PubMed

 14285.

after Vma9p has been removed by detergent the purified enzyme is still able to perform fully-coupled ATP-dependent proton pumping.[Vma9] (Mus musculus) PubMed

 14286.

Two-component regulators control hilA expression by controlling fimZ and hilE expression within Salmonella enterica serovar Typhimurium. [hilE] (Mus musculus) PubMed

 14287.

these results thus support the hypothesis that ZFR has essential roles during neurogenesis, and could support early steps of RNA transport and localization through RNA granule formation in the nucleus and/or to their nucleo-cytoplasmic shuttling.[ZFR] (Mus musculus) PubMed

 14288.

A time-resolved Raman spectroscopic analysis is combined with polyacrylamide gel electrophoresis (PAGE) to monitor nucleotide addition in single crystals of the Thermus thermophilus elongation complex RNAP.[RNAP] (Mus musculus) PubMed

 14289.

Polymyxin B resistance and biofilm formation in Vibrio cholerae are controlled by the response regulator CarR. [CarR] (Mus musculus) PubMed

 14290.

Fap2 of Fusobacterium nucleatum is a galactose-inhibitable adhesin involved in coaggregation, cell adhesion, and preterm birth. [Fap2] (Mus musculus) PubMed

 14291.

The sensor histidine kinase RgfC affects group B streptococcal virulence factor expression independent of its response regulator RgfA. [RgfC], [RgfA] (Mus musculus) PubMed

 14292.

c-MYC-acetylation is required for the cooperation between p30(II) and c-MYC which promotes proviral replication and contribute to HTLV-1-induced carcinogenesis.[p30(II)] (Mus musculus) PubMed

 14293.

The secreted effector protein EspZ is essential for virulence of rabbit enteropathogenic Escherichia coli O103:H2 (E22). [EspZ] (Mus musculus) PubMed

 14294.

Salmonella can simultaneously inhibit host B-and T-cell responses using SPI2-dependent mechanisms. [SPI2](Pathogenicity island 2 protein) (Mus musculus) PubMed

 14295.

findings show SHJG8833 is a positive regulator that controls cyclothiazomycin biosynthesis by activating structural genes in the clt cluster [SHJG8833] (Mus musculus) PubMed

 14296.

These results support previous suggestions that heterotropic inhibition and activation occur by different pathways prokaryotic PFK.[PFK] (Mus musculus) PubMed

 14297.

An intramolecular lock facilitates folding and stabilizes the tertiary structure of Streptococcus mutans adhesin P1. (Mus musculus) PubMed

 14298.

Crt10 was required for 25S nonfunctional rRNA decay, but not for DNA repair, suggesting that this accessory component specifies the function of the E3 complex differently.[Crt10, Rtt101] (Mus musculus) PubMed

 14299.

The data thus suggest that mature protein domains are translocated through a TatA and TaTB environment.(TatA protein, E coli) (Mus musculus) PubMed

 14300.

ZmWAK is the gene within qHSR1 conferring quantitative resistance to maize head smut. ZmWAK spans the plasma membrane, potentially serving as a receptor-like kinase to perceive and transduce extracellular signals. [ZmWAK] (Mus musculus) PubMed

 14301.

CtCBM35 displays low ligand-binding affinity with insoluble ivory nut mannans. [CtCBM35] (Mus musculus) PubMed

 14302.

Thus, Eng is a cyst-specific endo-beta-1,3-glucanase that may play a role in the major surface glycoprotein variant expression in Pneumocystis.[Eng] (Mus musculus) PubMed

 14303.

An uncharacterized 25 kDa protease was found from the cell wall of Candida glabrata. The protease showed gelatinolytic activity and was inhibited by PMSF, a known serine protease inhibitor.[serine protease] (Mus musculus) PubMed

 14304.

A glycoprotein named BcGs1 was identified by 2D electrophoresis and mass spectrometry. Functional domain analysis indicated that BcGs1 was a glucan 1,4-alpha-glucosidase. [BcGs1] (Mus musculus) PubMed

 14305.

This study is the first to identify an Elov12 in rainbow trout (Oncorhynchus mykiss) and functionally chafacterise the Elovl5 and Elovl2 using a yeast expression system.[Elov15] (Mus musculus) PubMed

 14306.

we engaged C. elegans mutants and identified that the p38 MAPK signaling, insulin/IGF-1 signaling (IIS), and HSF-1 play pivotal roles in the WCESP-mediated host immune response (Mus musculus) PubMed

 14307.

Using conventional and conditional loss-of-function approaches we showed that SEMP1 is not essential for parasite survival, gametocytogenesis, or PfEMP1 export under culture conditions (Mus musculus) PubMed

 14308.

Marek's disease virus microRNA-155 activates the oncogene c-Myc by targeting LTBP1 and suppressing the TGF-beta signaling pathway.[miR-M4-5p] (Mus musculus) PubMed

 14309.

E2a is necessary to drive transcription of Smad2/3 target genes, including critical regulators of dorsal cell fate and morphogenesis[E2a] (Mus musculus) PubMed

 14310.

The role of selected key amino acid residues of the NuoD segment, in NDH-1 structure and function was investigated.[NuoD, NDH-1] (Mus musculus) PubMed

 14311.

Lr70 is a new gene for leaf rust resistance [Lr70] (Mus musculus) PubMed

 14312.

work uncovers a novel mechanism for small-RNA-mediated epigenome regulation and highlights fundamental roles for Paf1C and the RNAi machinery in building epigenetic memory [Paf1] (Mus musculus) PubMed

 14313.

NHR-176 regulates cyp-35d1 to control hydroxylation-dependent metabolism of anthelmintic thiabendazole in Caenorhabditis elegans. [cyp-35d1] (Mus musculus) PubMed

 14314.

Authors demonstrated that the EHEC lpf2 operon is regulated in response to temperature, pH, bile salts and iron, during the exponential phase of growth, and is controlled by Fur.[lpfA2] (Mus musculus) PubMed

 14315.

Transmembrane oligomeric form of Vibrio cholerae cytolysin (VCC) triggers TLR2/TLR6-dependent proinflammatory responses in monocytes and macrophages. [VCC] (Mus musculus) PubMed

 14316.

The dimeric TatA structure offers more detailed information of TatA oligomeric interface and provides new insights on Tat translocation mechanism.[TatA] (Mus musculus) PubMed

 14317.

Ssn6 has dual roles in filament development, depending on the interaction with Rpd31. (Mus musculus) PubMed

 14318.

Dpm protein is secreted during growth in vitro and upon macrophage infection. Dpm is an inactive phosphatase, suggesting that its contribution to phagosomal maturation arrest must be unrelated to tyrosine phosphatase activity. [Dpm, strain K56-2] (Mus musculus) PubMed

 14319.

SNF1 pathway is required for fungal development and facilitates pathogenicity by its contribution to peroxisomal maintenance and lipid metabolism in M. oryzae.[SNF1] (Mus musculus) PubMed

 14320.

These results suggest that PK1 protein kinase prevents apoferritin from iron loading, and thus stabilizes the cellular iron levels.[PK1] (Mus musculus) PubMed

 14321.

Lr73 gene confers seedling resistance to Puccinia triticina [Lr73] (Mus musculus) PubMed

 14322.

all of the SHR proteins function as mobile signals (Mus musculus) PubMed

 14323.

Cerebral malaria isolates bind significantly more to CD36 than to ICAM-1, which was correlated with high transcription level of group B var genes, supporting their implication in malaria pathogenesis.[var] (Mus musculus) PubMed

 14324.

The antimicrobial susceptibilities of Escherichia coli isolated from dogs and the association expression of the AcrAB-TolC efflux pump are reported.[AcrAB-TolC] (Mus musculus) PubMed

 14325.

NMR spectroscopy reveals, the rhombicity of the electronic structure of low-spin paramagnetic hemes determines their relative contribution to the preferential orientation of Small Tetraheme Cytochrome (STC) when placed in a strong magnetic field. [STC] (Mus musculus) PubMed

 14326.

Orsellinic acid is hypothesized to be the PKS release product which is transformed to orcinol through decarboxylation.[PKS14] (Mus musculus) PubMed

 14327.

The transcription pattern of stimulation of sulfur-containing amino acids and purine synthesis decreased, or even disappeared, in the W303-Deltasky1 strain. [Sky1, Strain W303] (Mus musculus) PubMed

 14328.

The two proteins Rag3 and KlPdc1 interact, co-localize in the cell and that KlPdc1 may control Rag3 nuclear localization. [RAG3, PDC1] (Mus musculus) PubMed

 14329.

The laboratory evolution of two orthogonal sortase A variants that recognize each of two altered substrates, LAXTG and LPXSG, with high activity and specificity, is reported.[Sortase A] (Mus musculus) PubMed

 14330.

ClpA engagement of the ClpS N-terminal extension is crucial for ClpS-mediated substrate delivery.[ClpS] (Mus musculus) PubMed

 14331.

we demonstrate that KcsA can be reconstituted into planar lipid bilayers directly from native nanodiscs, which enables functional characterization of the channel by electrophysiology without first depriving the protein of its native environment. (Mus musculus) PubMed

 14332.

Here, both elementary steps (glycosylation and deglycosylation) of the Chitinase B-catalyzed reaction are investigated by means of combined quantum mechanics/molecular mechanics (QM/MM) umbrella sampling molecular dynamics (MD) simulations. [Chitinase B] (Mus musculus) PubMed

 14333.

NrdR and DnaB from S. pyogenes were involved in response to host defense; however, the contribution of NrdR alone was not substantial. [NrdR; DnaB] (Mus musculus) PubMed

 14334.

We also showed that the suppression of cellulase expression by CLP1 occurred by repressing the expression of cellodextrin transporters, particularly cdt1 expression (Mus musculus) PubMed

 14335.

viral RNA replication and release were significantly suppressed in BIK-depleted cells and over-expression of the RNA-dependent RNA polymerase, NS5B, was able to induce BIK expression (NS5B) (Mus musculus) PubMed

 14336.

characterised vOX2 with biochemical, biophysical and bioinformatics tools and as a result propose a 3-dimensional model for vOX2 based on structural and functional homology with the PD-L1 protein (OX2) (Mus musculus) PubMed

 14337.

A structure at 2.8-A resolution of a cocrystal of a She2p tetramer bound to a segment of She3p, is reported. (Mus musculus) PubMed

 14338.

These data support a model in which HD5 prevents furin from accessing human papillomavirus 16 L2 by occluding the furin cleavage site via direct binding to the viral capsid.[L2] (Mus musculus) PubMed

 14339.

Influenza viral neuraminidase enhances the expression of cellular adhesins through the activation of TGF-beta, leading to increased bacterial loading in the lungs.[Neuraminidase] (Mus musculus) PubMed

 14340.

AM1 was induced by salt and PEG, and am1 showed enhanced sensitivity to salinity in seed germination and increased tolerance to drought. [AM1] (Mus musculus) PubMed

 14341.

A grain-weight quantitative trait locus (QTL) encoding a new-type GNAT-like protein that harbors intrinsic histone acetyltransferase activity (OsglHAT1), was identified.[HAT1] (Mus musculus) PubMed

 14342.

PM VII depleted mutants exhibited no defects in development and progressed normally throughout the parasite life cycle.[PM VII} (Mus musculus) PubMed

 14343.

DEET, picaridin, insect repellent 3535, and p-menthan-3,8-diol activate CquiOR136. Reduction of CquiOR136 transcript levels decreased antenna responses to DEET and abolished repellancy. CquiOR136. (Mus musculus) PubMed

 14344.

isolated and cloned a CER1 homolog CsCER1, and we found that the expression of CsCER1 in the cucumber line 3401 which shows waxy fruit phenotype is much higher than that in the cucumber line 3413 which displays glossy fruit phenotype (CER1) (Mus musculus) PubMed

 14345.

Salinity and drought stress induces elevated expression of miR319. [miR319] (Mus musculus) PubMed

 14346.

boron transporter needed for pollen germination to fertilization [Bor4] (Mus musculus) PubMed

 14347.

Dma1p-dependent degradation is not restricted to the SIN, as we show that Dma1p is needed for the degradation of Mcp6p (also known as Hrs1p) during meiosis I. (Mus musculus) PubMed

 14348.

Absence of SUN-domain protein Slp1 blocks karyogamy and switches meiotic recombination and synapsis from homologs to sister chromatids. (Mus musculus) PubMed

 14349.

Single-molecule fluorescence spectroscopy was used to investigate how the DnaJ-DnaK chaperone system alters the conformational distribution of the denatured substrate protein rhodanese.[DnaJ, DnaK] (Mus musculus) PubMed

 14350.

PHANTASTICA has roles in leaf polarity establishment and leaf petiole identity regulation (PHANTASTICA). (Mus musculus) PubMed

 14351.

action of SERF1 in signal communication to the shoot is independent from abscisic acid, but does affect the accumulation of ROS-related metabolites and transcripts under short-term salt stress [SERF1] (Mus musculus) PubMed

 14352.

KaiA and KaiC localize as discrete foci near a single pole of cells in a clock-dependent fashion, with enhanced polar localization observed at night. KaiA and KaiC colocalize with each other, as well as with CikA.[KaiA,KaiC,CikA] (Mus musculus) PubMed

 14353.

Inhibition of the RIG-I-like receptors (RLRs) by pathogenic arenavirus Z proteins is mediated by the protein-protein interactions of Z and RLRs. (Mus musculus) PubMed

 14354.

ocpG intron retention was affected by the secondary structures of intronic mRNA (Mus musculus) PubMed

 14355.

Difference in leaf margin dissection between the sister species Capsella rubella and Capsella grandiflora is caused by cis-regulatory variation in the homeobox gene RCO-A, which alters its activity in the developing lobes of the leaf.[RCO] (Mus musculus) PubMed

 14356.

ATG7 is required for autophagy-dependent lipid metabolism in rice anther development.[ATG7, rice] (Mus musculus) PubMed

 14357.

Data indicate that CtGEN1 is a nuclease and selective for the structure of four-way DNA junctions: [GEN1] (Mus musculus) PubMed

 14358.

DHHC6, contains a predicted Src-homology 3 (SH3) domain and DHHC6 is localized to the ER membrane. DHHC6/Selk interactions in the ER membrane that depended on SH3/SH3 binding domain interactions (Mus musculus) PubMed

 14359.

DTH7 encodes a pseudo-response regulator protein. Its expression is regulated by photoperiod. In long days DTH7 acts downstream of phytochrome B to repress Ehd1 expression. DTH7. (Mus musculus) PubMed

 14360.

discovery of the critical interactions between PfRH5, PfRipr, and the GPI-anchored CyRPA clearly defines the components of the essential PfRH5 adhesion complex for P. falciparum erythrocyte invasion (Mus musculus) PubMed

 14361.

Arg145 and Arg256 in the inducer-binding cavity are important for CcpE allosteric activation by citrate. CcpE tunes the expression of 126 genes. It is an important metabolic sensor that adjusts the metabolic state and coordinates virulence. CcpE. (Mus musculus) PubMed

 14362.

low level of PE causes ER stress, disrupts vesicle trafficking, and causes alpha-syn to accumulate; such cells likely die from a combination of ER stress and excessive accumulation of alpha-syn. (Mus musculus) PubMed

 14363.

Substantial structural rearrangements at 42 degrees C were observed in the heat-shock sigma factor 32 around the N-terminus (residues 11-60, which cover the DnaJ binding region) and the region spanning residues 190-210. [heat-shock sigma factor 32] (Mus musculus) PubMed

 14364.

These data suggest that the JH regulatory pathway, the transcription factor Bmdimm, and the targeted fib-H gene contribute to the synthesis of fibroin H-chain protein in B. mori (Mus musculus) PubMed

 14365.

These results suggest that differences in the middle domain of Hsp90alpha and Hsp90beta may be responsible for the isoform-specific interactions with selected proteins.[Hsp90] (Mus musculus) PubMed

 14366.

Maize SBP-box transcription factors unbranched2 and unbranched3 affect yield traits by regulating the rate of lateral primordia initiation. (Mus musculus) PubMed

 14367.

EGCrP2, classified into glycohydrolase family 5, is the first steryl-b-glucosidase identified as well as a missing link in sterylglucoside metabolism in fungi. (Mus musculus) PubMed

 14368.

Substitution of key residues of the OmpD channel modifies hydrogen peroxide and hypochlorous acid transport through the porin. [OmpD] (Mus musculus) PubMed

 14369.

NAADP induced marked Ca(2+) transients in HEK293 cells that stably coexpressed hTPC2 with hTPC1 or cTPC3, but failed to evoke any such response in cells that coexpressed interacting hTPC2 and rTPC3 subunits (Mus musculus) PubMed

 14370.

VopQ inhibits yeast vacuole fusion.[VopQ] (Mus musculus) PubMed

 14371.

the molecular details of the interaction of metallochaperones UreE and HypA in Helicobacter pylori, are reported.[HypA, UreE] (Mus musculus) PubMed

 14372.

This work simulates the response regulator RR468 from Thermotoga maritima, in which phosphorylation and dephosphorylation of a conserved aspartate residue acts as a switch via a large conformational change concentrated in three proximal loops. [RR468] (Mus musculus) PubMed

 14373.

These findings support a role of GroEL in DMSO reductase maturation that likely involves its chaperonin function for assisting in folding of the DmsA preprotein.[DmsD, GroEL] (Mus musculus) PubMed

 14374.

A'alpha helix directly modulates the oligomerization state of the light-, oxygen-, or voltage-sensitive (LOV) domain, whereas the Jalpha helix acts as an allosteric regulator. [aureochrome1a] (Mus musculus) PubMed

 14375.

study found expression of SamDC gene is inducible by abiotic stresses like salinity, drought, and cold, as well as by light and abscisic acid treatment [SamDC] (Mus musculus) PubMed

 14376.

two transcripts with different expression patterns: ASL1.1 expressed in most organs throughout the whole growth period; OsASL1.2 mainly expressed in the roots [ASL1] (Mus musculus) PubMed

 14377.

Data suggest that PI5P4K gamma plays role in development/differentiation and maintenance of epithelial cell functional polarity in kidney cortical duct. [PI5P4K gamma, phosphatidylinositol 5-phosphate 4-kinase gamma] (Mus musculus) PubMed

 14378.

Data suggest that TamR regulates citric acid cycle enzymes; expression of tam, malate synthase, malate dehydrogenase, and isocitrate dehydrogenase is induced when citrate or trans-aconitate accumulate. [tam, trans-aconitate methyltransferase] (Mus musculus) PubMed

 14379.

NPR-4 is activated by FMRFamide-like peptides and intracellular signalling via Galphai mediated pathways. [NPR-4] (Mus musculus) PubMed

 14380.

Data indicate the requirement of histone modification by PR domain containing 12 (PRDM12) and histone demethylase Kdm4a for pre-placodal ectoderm and neural crest development: [Kdm4a] (Mus musculus) PubMed

 14381.

Escherichia coli RNase H spectroscopic characterization and the response of the mimics to further mutation are consistent with studies on the transient kinetic intermediate, indicating that they model the early intermediate.[RNAse H] (Mus musculus) PubMed

 14382.

Kinetics and intermediates of the reaction of fully reduced Escherichia coli Cytochrome b03 with O2. [Cytochrome b03] (Mus musculus) PubMed

 14383.

SPX1 and SPX2 inhibition of OsPHR2 activity is phosphate-dependent.[SPX1, SPX2, PHR2] (Mus musculus) PubMed

 14384.

RcsF has a transmembrane topology with the lipidated N terminus on the cell surface and the C-terminal signaling domain in the periplasm.[RcsF] (Mus musculus) PubMed

 14385.

The data indicates that PCG2 employs an unusual mode of binding to target DNA and demonstrates the versatility of winged helix-turn-helix domains (PCG2). (Mus musculus) PubMed

 14386.

eIF5B overexpression promotes maturation of G0-like immature oocytes and causes cell death, an alternative to G0, in serum-starved THP1 cells.[eIF5B] (Mus musculus) PubMed

 14387.

NS5B polymerase activity was significantly reduced by silencing human RacGAP1 and, vice versa, was increased by overexpression of RacGAP1 in a cell-based reporter assay. (NS5B polymerase) (Mus musculus) PubMed

 14388.

This study describes a model of S. marcescens pneumonia that mimics known clinical features of human illness, identifies neutrophils and the toxin ShlA as a key factors important for defense and infection. [ShlA] (Mus musculus) PubMed

 14389.

glpQ2 enhances surface phosphorylcholine expression in S. pneumoniae 19AST320 during the exponential phase, which contributes to the severity of pneumonia by promoting adherence and host cell cytotoxicity. [glpQ2] (Mus musculus) PubMed

 14390.

The sheath subunits, composed of tightly interacting proteins VipA and VipB, assemble into a six-start helix. The helix is stabilized by a core domain assembled from four beta strands donated by one VipA and two VipB molecules.[VipA, VipB] (Mus musculus) PubMed

 14391.

Data indicate that an alpha helix in the N-terminal extension of orange carotenoid protein (OCP) plays a key role in the photoactivation process: [OCP] (Mus musculus) PubMed

 14392.

The Escherichia coli rpsD and rpsE genes encoding the S4 and S5 proteins were targeted for mutagenesis and screened for accuracy-altering mutations. [rpsD; rpsE] (Mus musculus) PubMed

 14393.

Micelle-catalyzed domain swapping in the GlpG rhomboid protease cytoplasmic domain.[GlpG] (Mus musculus) PubMed

 14394.

Data indicate that the purified enzyme succinic semialdehyde dehydrogenase (SSADH) was specific for its substrates succinic semialdehyde (SSA) and NAD+. (Mus musculus) PubMed

 14395.

In polyploids, diploid-like chromosome pairing is controlled by the Ph1 gene via preventing homeologous chromosome pairing. Despite a conserved DNA sequence, Ph1 gene homeologues showed a different structure and expression pattern. (Pairing homeologous 1) (Mus musculus) PubMed

 14396.

Main conformational changes that occurred upon cyclobutane pyrimidine dimer substrate binding and release with photolyase were due to the changes in the conformation of the apoenzyme and the repaired cyclobutane pyrimidine dimer.[photolyase] (Mus musculus) PubMed

 14397.

The binding and cleavage of 5-methylcytosine DNA by Tbis1 are discussed in relation to the SET and RING-finger-associated (SRA) domain and the HNH nuclease domain of Tbis1 (Tbis1). (Mus musculus) PubMed

 14398.

results identify a bacterium-dependent, tumorimmune evasion mechanism in which tumors exploit the Fap2 protein of F. nucleatum to inhibit immune cell activity via TIGIT. [Fap2] (Mus musculus) PubMed

 14399.

fine-tuning of HlyA expression by the CpxRA system is critical for enhancing uropathogenic Escherichia coli fitness in the urinary bladder.[HlyA] (Mus musculus) PubMed

 14400.

The thermodynamic features of the IIA(Glc)-LacY interaction as measured by isothermal titration calorimetry, are reported.[LacY, IIA(glc) (Mus musculus) PubMed

 14401.

Data indicate that serine hydroxymethyltransferase (SHMT) is a direct miR-1174 target: [miR-1174] (Mus musculus) PubMed

 14402.

Data suggest that the thermostable lichenase lichenase (endo-beta-1,3;1,4-glucan-D-glycosyl hydrolase) circular permutation predictions can be used in search for internal integration sites within protein: [lichenase] (Mus musculus) PubMed

 14403.

Data indicate that serine hydroxymethyltransferase (SHMT) is a direct miR-1174 target: [miR-1174] (Mus musculus) PubMed

 14404.

FRE10 was highly expressed at acidic pH, compared to that at alkaline pH, whereas the expression of FRE2 was just the opposite. [Fre10, Fre2] (Mus musculus) PubMed

 14405.

PfDHHC1 is a member of a highly conserved, apicomplexan-specific clade of palmitoyl acyltransferases [DHHC1] (Mus musculus) PubMed

 14406.

Incubation of cMC2R/cMRAP1 transfected cells with alanine substituted analogs of hACTH(1-24) at amino acid positions F(7) or W(9) completely blocked stimulation of the transfected cells.[MRAP1] (Mus musculus) PubMed

 14407.

SpILP1 and SpILP2 transcripts are expressed in different compartments during embryo/larva development and that the SpILP1 protein mature form differs in the egg and the larva, suggesting different biological roles.SpILP1, SpILP2] (Mus musculus) PubMed

 14408.

The mechanism of SepD and SepL control of translocator secretion and secretion hierarchy between translocators and effectors was studied.[SepD; SepL] (Mus musculus) PubMed

 14409.

These results demonstrate that RNase III activity on proP mRNA degradation is downregulated in Escherichia coli cells under osmotic stress.[proP; RNase III] (Mus musculus) PubMed

 14410.

Merkel cell polyomavirus large tumor antigen phosphorylation at serine 816 by ATM kinase induces apoptosis in host cells [MCV LT] (Mus musculus) PubMed

 14411.

The second is that Dialkylglycine decarboxylase must catalyze transamination at the same active site in the second half-reaction of the ping-pong catalytic cycle (Mus musculus) PubMed

 14412.

Structural basis for the formation of acylalkylpyrones from two beta-ketoacyl units by the fungal type III polyketide synthase CsyB. (Mus musculus) PubMed

 14413.

analysis of interaction of Toxoplasma gondii MIC2-associated protein with MIC2 [MIC2] (Mus musculus) PubMed

 14414.

The interplay of the adiponectin system, TNFalpha and insulin at a transcriptional level and, their effects on the adipogenic transcription factor PPARgamma, as well as on the activation of main insulin signaling pathways, is reported.[TOR, AKT] (Mus musculus) PubMed

 14415.

Bivalent ligation of the collagen-binding modules of fibronectin by SFS, a non-anchored bacterial protein of Streptococcus equi. (Mus musculus) PubMed

 14416.

Glucose was shown to exhibit a repressive effect on inulinase synthesis by K. marxianus. [Inulinase] (Mus musculus) PubMed

 14417.

Csd4 activity relies on a Gln-zinc ligand to cleave cell wall tripeptides and produce helical shape. (Mus musculus) PubMed

 14418.

H-NS represses and VirB partially derepresses the ospZ promoter. H-NS-mediated repression requires sequences located between -731 and -412 relative to the beginning of the ospZ gene. (Mus musculus) PubMed

 14419.

MocA is a specific cytidylyltransferase involved in molybdopterin cytosine dinucleotide biosynthesis in Escherichia coli [MocA] (Mus musculus) PubMed

 14420.

Results confirmed the signaling pathway from srrX through srrA to srrY, leading to lankacidin and lankamycin production [srrY] (Mus musculus) PubMed

 14421.

Evaluation of Rot binding to different activated and repressed promoters revealed that certain mutations on Rot exhibit promoter-specific effects, suggesting for the first time that Rot differentially interacts with target promoters.[rot] (Mus musculus) PubMed

 14422.

Yr61 is a stripe rust resistance gene in winter wheat cultivar Pindong 34 [Yr61] (Mus musculus) PubMed

 14423.

miR-K12-11 establishes its gene regulatory networks by both repressing master transcription factors and influencing signaling pathways, to counter the host anti-viral response and to promote proliferation and survival of infected cells. (Mus musculus) PubMed

 14424.

The Plasmodium protein P113 supports efficient sporozoite to liver stage conversion.p113 is dispensable for Plasmodium life cycle progression and plays auxiliary roles during pre-erythrocytic development.[P113] (Mus musculus) PubMed

 14425.

Calcineurin(CnA) modulates growth, stress tolerance, and virulence. [CnA] (Mus musculus) PubMed

 14426.

CYP321E1 was expressed at all developmental stages of P. xylostella but was highest in the fourth-instar larvae. Expression was differentially affected by three representative insecticides, alphamethrin, abamectin and chlorantraniliprole.[CYP321E1] (Mus musculus) PubMed

 14427.

It was concluded that the inhibition of protein kinase A (PRKA) signaling pathway can aid in reducing the degree of nephrotoxicity caused by cyclosporine.[PRKA] (Mus musculus) PubMed

 14428.

These data indicate that CpsC possesses a varied topology, with the C terminus flipping across the cytoplasmic membrane, where it interacts with CpsD in order to regulate tyrosine kinase activity.[CpsC] (Mus musculus) PubMed

 14429.

Data show that tRNA (m1A58) methyltransferase (TrmI) specifically recognize substrate tRNAs: [TrmI] (Mus musculus) PubMed

 14430.

TaCWI-5 has anther-specific expression, and is associated with plant height and tiller number [TaCWI] (Mus musculus) PubMed

 14431.

Extracellular loop 4 of the proline transporter PutP controls the periplasmic entrance to ligand binding sites.[PutP] (Mus musculus) PubMed

 14432.

The structure and function of a dual RCK-containing, multi-ligand gated K+ channel from Geobacter sulfurreducens (Gsuk), have been presented. [GsuK]. (Mus musculus) PubMed

 14433.

Engineering of tumor antigen-specific CD8+ T-cells to overexpress miR-17-92 improves type-1 effector functions, such as enhanced IFN-gamma production and cytotoxicity. [miR-17-92] (Mus musculus) PubMed

 14434.

Full-length OmpA protein is partially present as a dimer.The dimer interface is localized on the soluble C-terminal domain of OMPA protein.[OMPA] (Mus musculus) PubMed

 14435.

The effects of MIG1 and/or TUP1 and/or SSN6 deletion on the alleviation of glucose-repression to promote maltose metabolism and leavening ability of baker's yeast, is reported.[MIG1, TUP1, SSN6] (Mus musculus) PubMed

 14436.

The ISA1 homo-oligomer is essential, but not the ISA1-ISA2 oligomer, for starch production in rice endosperm. [OzISA1] (Mus musculus) PubMed

 14437.

Membrane proteins ExbB and ExbD form a complex of 4:2 stoichiometry.Coordinated rearrangements between cytoplasmic and periplasmic domains of the membrane protein complex ExbB-ExbD of Escherichia coli.[ExbB] [ExbD] (Mus musculus) PubMed

 14438.

Crystall structure of YmfB explains its divalent metal ion-based catalytic mechanism of action. [YmfB] (Mus musculus) PubMed

 14439.

a structural explanation for the strict monomethylation activity of PRMT7 [PRMT7] (Mus musculus) PubMed

 14440.

CagL forms a three-dimensional domain-swapped dimer.The RGD motif of dimeric CagL adopts an alpha-helical conformation. [cagL] (Mus musculus) PubMed

 14441.

ORC1, CDC6 and MCM7 distinct associate with chromatin through Trypanosoma cruzi life cycle.[orc1] [cdc6] [mcm7] (Mus musculus) PubMed

 14442.

[MHC class II beta-1 ] One single nucleotide polymorphism of the MHC class II beta-1 domain and one haplotype were associated with resistance to lactococcosis. (Mus musculus) PubMed

 14443.

Only the oxidized OxyR2 activated prx2. [OxyR2, prx2] (Mus musculus) PubMed

 14444.

MOP1 contributions to nucleosome position may be either separate from changes in gene expression, or cooperative with development and other levels of regulation in coordinating gene expression.[new entry] (Mus musculus) PubMed

 14445.

Through the binding and degradation of histones in the skin epidermis by FAF and SufA, F. magna is protected from their antimicrobial activity(SufA and FAF). (Mus musculus) PubMed

 14446.

Data show that heparin binding protein WGA16 is a sperm lectin: [WGA16] (Mus musculus) PubMed

 14447.

Thermotoga maritima DHFR lacks the coupling of protein motions to the reaction coordinate that have been identified for Escherichia coli DHFR catalysis. Dynamical coupling isn't a universal phenomenon that affects the efficiency of enzyme catalysis.[DHFR] (Mus musculus) PubMed

 14448.

These data indicate that N-acetylated alpha-linked acidic dipeptidase of H. capsulatum is recognized as a major antigen during histoplasmosis. [N-acetylated alpha-linked acidic dipeptidase] (Mus musculus) PubMed

 14449.

PotD is involved in both the uptake and the excretion of spermidine.[PotD] (Mus musculus) PubMed

 14450.

dDia1 is critically involved in collective cell migration during terminal differentiation.[dDial1] (Mus musculus) PubMed

 14451.

Pollen hydration is regulated by MLO12, possibly through an interaction with calmodulin in the cytosol. [MLO12] (Mus musculus) PubMed

 14452.

The zinc-dependent enzyme catalyzes the deamination of cytosine to form uracil and ammonia. The calculations give a description of the catalytic mechanism and establish the role of important active-site residues. [zinc-dependent cytosine deaminase] (Mus musculus) PubMed

 14453.

Tfp is key factor in initial stages of Citrus sinensis infection by Xanthomonas citri subsp. citri.[Tfp] (Mus musculus) PubMed

 14454.

The XH domain of XHS5 protein is necessary for interacts with itself and XHS2 protein.[XHS5][XHS2] (Mus musculus) PubMed

 14455.

Structural basis for proteasome formation controlled by an assembly chaperone nas2.Nas2 binds to the Rpt5.[Nas2] [Rpt5] (Mus musculus) PubMed

 14456.

The study reports the use of solution structures of Pol X in the free, binary (Pol X:MgdGTP), and ternary (Pol X:DNA:MgdGTP with dG:dGTP non-Watson-Crick pairing) forms. [Pol X] (Mus musculus) PubMed

 14457.

(microRNA-424) MiR-424 protects against transient cerebral ischemia/reperfusion injury by inhibiting oxidative stress. (Mus musculus) PubMed

 14458.

COLD1 encodes a regulator of G-protein signaling that localizes on plasma membrane and endoplasmic reticulum; interacts with the G-protein alpha subunit to activate the Ca(2+) channel for sensing low temperature and to accelerate G-protein GTPase activity. [COLD1] (Mus musculus) PubMed

 14459.

cytoplasmic EhMLBP-containing granules are stress granules, and the formation of these granules is dependent upon EhMLBP and long interspersed nucleotide element. [MLBP] (Mus musculus) PubMed

 14460.

A conserved nuclear carrier Tsr2 coordinates transfer of the ribosomal protein eS26 to the earliest assembling pre-ribosome, the 90S. [eS26] (Mus musculus) PubMed

 14461.

These data suggest that the sisA and sisB genes may be important for suppressing the host immune response during the initial stages of infection.[SisA & SisB] (Mus musculus) PubMed

 14462.

A functional complementation of an lgg-1 null mutant with human GABARAP, its closer homolog showed that it localizes to autophagosomes and can rescue LGG-1 functions in the early embryo.[LGG-1] (Mus musculus) PubMed

 14463.

NMR structure of the mouse cytomegalovirus m04 extracellular domain. [m04 protein] (Mus musculus) PubMed

 14464.

PrnB, different from Put4p, its Saccharomyces cerevisiae orthologue, is a highly specific l-proline transporter of Aspergillus nidulans. (Mus musculus) PubMed

 14465.

The purified enzyme could efficiently unwind partial duplex DNA substrate in a 3' to 5' direction and could not unwind substrates with both 5' and 3' overhangs, those with a 5' overhang, or blunt-ended DNA duplexes.[RecQ1] (Mus musculus) PubMed

 14466.

pressure overload, while enhancing IL-18 and IL-18R expression in hypertrophied and failing hearts, markedly attenuated the level of expression of the endogenous IL-18 antagonist IL-18BP.[IL-18R] (Mus musculus) PubMed

 14467.

SAXS was used to determine the low-resolution structure of the outer-membrane protein OmpA from E. coli solubilized by the surfactant dodecyl maltoside. [OmpA] (Mus musculus) PubMed

 14468.

These results show that RavA acts as the RavR cognate histidine kinase, which fine-tunes RavR functions and enables bacteria to adapt quickly to intracellular changes.[RavA, RavR] (Mus musculus) PubMed

 14469.

over-expression of the OsPTR6 gene could increase rice growth through increasing ammonium transporter expression and glutamine synthetase activity but decreases nitrogen use efficiency under conditions of high ammonium supply. [OsPTR6] (Mus musculus) PubMed

 14470.

Null mutants of Tb927.10.6900 are unable to synthesize base J. (Mus musculus) PubMed

 14471.

The function of cytosolic fumarase in maize scutellum can be related to metabolism of succinate formed in the glyoxylate cycle.[Fumarase] (Mus musculus) PubMed

 14472.

NF-YA1 and NF-YA2 appear as early symbiotic regulators acting downstream of DMI3 and NIN and possibly within the same regulatory complexes as NSP1/2 to directly activate the expression of ERN1. [NF-YA1; NF-YA2] (Mus musculus) PubMed

 14473.

LTG1 is involved in adaptive growth and fitness under low ambient temperature through an auxin-dependent process.[LTG1] (Mus musculus) PubMed

 14474.

MEL1 protein binds to 21-nucleotide phased small interfering RNAs, generated from more than 700 lincRNAs. [MEL1] (Mus musculus) PubMed

 14475.

IL-37 requires the receptors IL-18Ralpha and IL-1R8 to carry out its multifaceted anti-inflammatory program upon innate signal transduction. [IL-37] (Mus musculus) PubMed

 14476.

Results show that functional and non-functional YqjA proteins form dimers in the membrane and the predicted TM helix six is especially crucial for homo-interaction. [YqjA] (Mus musculus) PubMed

 14477.

Authors demonstrate that the amino acid residues at positions 249, 309, and 339 of the PB2 protein from this A/Vietnam/UT36285/2010 H5N1 human isolate were responsible for its efficient replication in A549 cells.[PB2] (Mus musculus) PubMed

 14478.

Estrogen deficiency may cause mitochondrial compromise through miR-23a-mediated PGC-1alpha downregulation.[miR23a] (Mus musculus) PubMed

 14479.

The roles of CaMK4beta, CREB, and MST1 in the pathology of scrapie in mice is reported.[CaMK4beta] (Mus musculus) PubMed

 14480.

SH5 modulates seed shattering by enhancing abscission zone (AZ) development and inhibiting lignin biosynthesis. [SH5] (Mus musculus) PubMed

 14481.

Smk1 encodes a PPR-E protein that is required for nad7-836 editing, and this editing is critical to NAD7 function in complex-I assembly in mitochondria, and hence to embryo and endosperm development in maize and rice. [SMK1] (Mus musculus) PubMed

 14482.

Smk1 encodes a PPR-E protein that is required for nad7-836 editing, and this editing is critical to NAD7 function in complex-I assembly in mitochondria, and hence to embryo and endosperm development in maize and rice. [SMK1] (Mus musculus) PubMed

 14483.

These findings define the RGG domain of TgSsossB as a protein-protein interaction platform and underline the role of the TgAlba-TgSsossB complex in stress-mediated response.[SsossB] (Mus musculus) PubMed

 14484.

A49 represents the eleventh VACV Bcl-2 family protein and, despite these proteins sharing very low sequence identity, structure-based phylogenetic analysis shows that all poxvirus Bcl-2 proteins are structurally more similar to each other (Mus musculus) PubMed

 14485.

membrane structure of Kup domains [KUP] (Mus musculus) PubMed

 14486.

Single nucleotide substitutions at the 5'- and 3'-end of the GAT motif as well as different spacing between the CBC and HapX DNA-binding sites revealed a remarkable promiscuous DNA-recognition mode of HapX (Mus musculus) PubMed

 14487.

The results show that AC2 suppresses replication reproducibly in all assays and that AC3 counteracts this effect.[AC2] (Mus musculus) PubMed

 14488.

The rice LRR-RLK genes functions as receptors of external signals. [OsGIRL1] (Mus musculus) PubMed

 14489.

By further mapping, we found that polymorphisms in JHM.WU structural protein M and nonstructural replicase proteins nsp1 and nsp13 are essential for liver pathogenesis.[nsp1, nsp13, M] (Mus musculus) PubMed

 14490.

Data suggest microfilaments/intermediate filaments (not microtubules) are essential for nucleolar fusion in oogenesis/ectogenesis; disruption of microtubules can prevent pronuclear formation by maintaining high Mpf. [Mpf; maturation-promoting factor] (Mus musculus) PubMed

 14491.

Sr2 is a temperature-sensitive diploid wheat resistance gene effective against Puccinia graminis (Mus musculus) PubMed

 14492.

Maize roothairless5 gene controlling root hair initiation and outgrowth which encodes a monocotspecific NADPH oxidase involved in superoxide production. [RTH5] (Mus musculus) PubMed

 14493.

The findings describe a well-defined signaling pathway that regulates dendritic outgrowth in conditions of compromised oxidative phosphorylation and the resulting AMPK activation.[AMPK] (Mus musculus) PubMed

 14494.

Cloning of the first plant-kingdom gene known to encode a G4-binding protein, maize (Zea mays L.) nucleoside diphosphate kinase1 (ZmNDPK1), homolog to the human homologue NM23-H2. [NDPK1 protein, or NM23-H2 protein, zea mays] (Mus musculus) PubMed

 14495.

The transcriptional activators AraR and XlnR from Aspergillus niger regulate expression of pentose catabolic and pentose phosphate pathway genes.[AraR and XlnR] (Mus musculus) PubMed

 14496.

OsSTK1 functions as a positive regulator of OsNug2 by enhancing OsNug2 GTPase activity. In addition, phosphorylation of OsNug2 serine 209 is essential for its complete function in biological functional pathway. [OsNug2 and OsSTK1]. (Mus musculus) PubMed

 14497.

OsNRAMP5 was found to be highly expressed in hulls. It was also expressed in leaves but expression level decreased with leaf age. It was enriched in the vascular bundles of roots and shoots especially in the parenchyma cells surrounding the xylem.[Nramp5] (Mus musculus) PubMed

 14498.

Reciprocal interaction between fish TGF-beta1 and IL-1beta is responsible for restraining IL-1beta signaling activity in grass carp head kidney leukocytes.[TGF-beta1], [il-1beta] (Mus musculus) PubMed

 14499.

The role of the amino acids proximal to the [2Fe-2S] cluster in the reduction dynamics of the cluster has been probed using the small molecule modifier diethyl pyrocarbonate. [Rieske iron-sulfur protein] (Mus musculus) PubMed

 14500.

These results indicate that the VV1_1681 protein is involved in the vulnibactin export system of Vibrio vulnificus M2799.[VV1_1681 homolog] (Mus musculus) PubMed

 14501.

CjDsbA1 is the primary thiol-oxidoreductase affecting life processes associated with bacterial spread and host colonization and CjDsbA2 activity does not affect the same processes.[CjDsbA1, CjDsbA2] (Mus musculus) PubMed

 14502.

Schizosaccharomyces pombe Pxd1 promotes proper DNA repair by activating Rad16XPF and inhibiting Dna2. [Pxd1] (Mus musculus) PubMed

 14503.

We expect to use this knowledge of assembly properties of VcFtsZ for screening of small molecules against VcFtsZ for development of anti-cholera agent (Mus musculus) PubMed

 14504.

The mitochondrial targeting signal plays a role in localization to the mitochondria and is essential for the proper functioning of the CPD photolyase. (Mus musculus) PubMed

 14505.

The crystal structures of PseH, an N-acetyltransferase, alone and in complex with acetyl coenzyme A were determined at 1.95 A resolution. [PseH] (Mus musculus) PubMed

 14506.

Plasma-membrane Zygosaccharomyces rouxii Sod2-22 antiporter exports Na(+) and Li(+), but not K(+). Three-dimensional model reveals a hydrophobic filter in the cation translocation pathway. [Sod2-22] (Mus musculus) PubMed

 14507.

Substrate activation in flavin-dependent thymidylate synthase - findings suggest that an initial activation of the pyrimidine substrate by reduced flavin is required for catalysis. [flavin-dependent thymidylate synthase] (Mus musculus) PubMed

 14508.

The structural data and functional measurements indicate that allosteric coupling between ligand binding and dimerization in BirA is achieved via reciprocal communication of disorder-to-order transitions on two distant functional surfaces. [BirA] (Mus musculus) PubMed

 14509.

The pH-dependent binding pathway of HdeA comprises a partially unfolded, dimeric intermediate that becomes increasingly stable relative to the native dimer at lower pH values and displays key structural features for chaperone-substrate interaction. [HdeA] (Mus musculus) PubMed

 14510.

VP8 plays a role in resisting Promyelocytic leukemia-related host antiviral defenses by redistributing PML protein, a function that depends on the phosphorylation of VP8. [Major tegument protein VP8] (Mus musculus) PubMed

 14511.

Triatoma virus recombinant VP4 protein induces membrane permeability through dynamic pores. [VP4] (Mus musculus) PubMed

 14512.

Cell lineage tracking method using Rosa26 targeted swine models. (Mus musculus) PubMed

 14513.

This 5'UTR sequence of ribM constitutes a functional FMN-riboswitch in Corynebacterium glutamicum.[ribM] (Mus musculus) PubMed

 14514.

overexpression of yciW conferred tolerance to L-cysteine, but disruption of yciW increased L-cysteine production in E. coli [yciW] (Mus musculus) PubMed

 14515.

The clusters of basic amino acids in the carboxy terminus of AAP act as nuclear and nucleolar localization signals.[AAP] (Mus musculus) PubMed

 14516.

L2 was able to reverse silencing effective only in vegetative plants. [L2] (Mus musculus) PubMed

 14517.

AL2 was able to reverse silencing in both vegetative and reproductive plants. [AL2] (Mus musculus) PubMed

 14518.

The domain structure of the Streptomyces coelicolor ligase can be restructured into that of the paradigm Escherichia coli ligase. (Mus musculus) PubMed

 14519.

STE12 is required for the pathogenicity by regulating appressorium development and penetration. [STE12] (Mus musculus) PubMed

 14520.

data show the biometal copper in a new context and function and provide a chemical rationale for the comparatively high catalytic activity of MccA [MccA] (Mus musculus) PubMed

 14521.

The ternary structure of the Polepsilon catalytic subunit (Pol2) bound to a nascent G:C base pair.[Pol2] (Mus musculus) PubMed

 14522.

conditional regulation of SodA and SodB [SodA][SodB] (Mus musculus) PubMed

 14523.

Authors present here the results as the first biochemical evidence that Wzy functions in a distributive manner.[Wzy] (Mus musculus) PubMed

 14524.

Results showed that the chitinaseC gene from S. marcescens AS1.1652 strain was successfully cloned and expressed on the yeast cell surface. [ChitinaseC] (Mus musculus) PubMed

 14525.

Characterized is MoaA reaction product, describing the use of 2'-chloroGTP to trap the GTP C3' radical, generated by hydrogen atom transfer to the 5'-deoxyadenosyl radical, and the use of 2'-deoxyGTP to block a late step in the reaction sequence. [MoaA] (Mus musculus) PubMed

 14526.

Dihydroxyacetone kinase subunits control the action of DhaR transcription factor. Coiled-coil helices rotation transmits binding signal to the DhaR C-terminal domain.[Dhar] (Mus musculus) PubMed

 14527.

novel chimeric proteins including DeltaSEC2-DeltaSak and DeltaSak-DeltaSEC2 were constructed through the truncation of SEC2 and Sak without 9-Ala linker and His-tag... both the truncated proteins preserved nearly the same anti-tumor and thrombolytic activities. (Mus musculus) PubMed

 14528.

PfCENP-C is a true CENP-C homologue in Plasmodium falciparum which binds to the centromeric DNA and its dimerization domain is essential for its in vivo functions as a centromere protein.[CENP-C] (Mus musculus) PubMed

 14529.

Avian infectious bronchitis virus papain-like protease cleaves Lys48- and Lys63-linked polyubiquitin. The crystal structure reveals a markedly different set of residues for binding substrates. [papain-like protease] (Mus musculus) PubMed

 14530.

Deletion of the two predicted trehalases in the C. neoformans genome, NTH1 and NTH2, resulted in severe defects in spore production, a decrease in spore germination, and an increase in the production of alternative developmental structures (Mus musculus) PubMed

 14531.

Aph1 is the major extracellular and vacuolar acid phosphatase in C. neoformans and that it is phosphate repressible. [Aph1] (Mus musculus) PubMed

 14532.

Mhb1p contains two putative HMG boxes contributing both to DNA binding and to its ability to compact mtDNA in vitro. (Mus musculus) PubMed

 14533.

Biochemical characterization of the SPATE members EspPalpha and EspI [EspI] (Mus musculus) PubMed

 14534.

Biochemical characterization of the SPATE members EspPalpha and EspI [ESPPalpha] (Mus musculus) PubMed

 14535.

The structure of an interloop disulfide bond form of DsbB, an intermediate in catalysis, was determined.[DsbB] (Mus musculus) PubMed

 14536.

FK506-binding protein like (FKBPL) is an important regulator of developmental and pathological angiogenesis. (Mus musculus) PubMed

 14537.

This study showed that the ugp operon is important for the selection of PHO-constitutive mutants under prolonged nutritional stress and that phoR mutations can be selected only in bacteria lacking pitA.[PitA] (Mus musculus) PubMed

 14538.

the role of His85 in the activity of CstII has been investigated by mutating it to Ala, Phe, Trp or Tyr. His85 is found to be essential for alpha2,3-sialyltransferase activity but not alpha2,8-sialyltransferase activity [CstII] (Mus musculus) PubMed

 14539.

Data suggest that conformation/stability of the oxygen-evolving protein is affected by other proteins of photosystem II, primarily by PsbO with smaller effects from PsbV and PsbU. [PsbQ, oxygen-evolving protein of photosystem II] (Mus musculus) PubMed

 14540.

flbD has conserved regulatory functions for conidiogenesis in A. nidulans and F.graminearum; it is responsible for hyphal differentiation in sexual and asexual reproduction; abaA-wetA pathway is positively regulated by FgFlbD during conidiogenesis [FibD] (Mus musculus) PubMed

 14541.

Pex3 has a role beyond simple docking of Atg30 and that its interaction with Atg30 regulates pexophagy in the yeast P. pastoris. (Mus musculus) PubMed

 14542.

The Xenopus laevis trpc2 gene is expressed in both the main olfactory epithelium (MOE) and the vomeronasal epithelium. This is the first description of a broad trpc2 expression in the MOE of a tetrapod.[trpc2] (Mus musculus) PubMed

 14543.

The results from these studies show that proton uptake to the pump site (time constant approximately 65 mus in the wild-type cytochrome c oxidase) was impaired in the Asp372Ile variant.[ba3 oxidase] (Mus musculus) PubMed

 14544.

An argD Tn5 transposon mutant that has the Tn5 transposon inserted after nucleotide 999 in the argD gene-coding region, was an arginine auxotroph that did not cause fire blight in apple and had reduced virulence in immature pear fruits.[ArgD] (Mus musculus) PubMed

 14545.

Authors show that CdiA C-terminal region toxin translocation requires the proton-motive force (pmf) within target bacteria.[CdiA] (Mus musculus) PubMed

 14546.

The x-ray structure of FaeG bound to lactose. [FaeG] (Mus musculus) PubMed

 14547.

Atg13 forms a scaffold for the preautophagosomal structure via its C-terminal disordered region, and subsequently it recruits Atg9 vesicles via its N-terminal HORMA domain.[Atg13, Atg9] (Mus musculus) PubMed

 14548.

By upregulating the expression of PEPCK gene, NS5A promotes the production of hepatic glucose which may contribute to the development of Hepatitis C-associated type 2 diabetes mellitus. [NS5A] (Mus musculus) PubMed

 14549.

10 aa deletion at positions 93-102 of 3A protein is associated with the virus replication efficiency. [3A] (Mus musculus) PubMed

 14550.

Disruption of ac78 results in decreased production of multiple nucleocapsid-enveloped occlusion-derived virions. [Ac78] (Mus musculus) PubMed

 14551.

VP53, VP37 and LCP encoded by RNA2 of broad bean wilt virus 2 (BBWV-2), a member of the genus Fabavirus, are strong suppressors of RNA silencing triggered by single-stranded sense RNA.[VP53, VP37, LCP] (Mus musculus) PubMed

 14552.

These results provide a compelling molecular mechanism for allosteric activation of DegS by outer-membrane proteins-peptide binding.[DegS] (Mus musculus) PubMed

 14553.

data suggest that StuA plays an important role in cell wall biogenesis during the development of A. nidulans, by controlling the transcription level of fksA [fksA] (Mus musculus) PubMed

 14554.

G288D AcrB altered substrate specificity, conferring decreased susceptibility to the fluoroquinolone antibiotic ciprofloxacin by increased efflux.[AcrB] (Mus musculus) PubMed

 14555.

G288D AcrB altered substrate specificity, conferring decreased susceptibility to the fluoroquinolone antibiotic ciprofloxacin by increased efflux.[AcrB] (Mus musculus) PubMed

 14556.

OsGLYII-2 contains a binuclear Zn/Fe centre that is essential for its Glyoxalase II (GLY II) activity, which is found to be dependent on the ambient glutathione (GSH) level. (Mus musculus) PubMed

 14557.

RCN1/OsABCG5 has a role in the suberization of the hypodermis of rice roots, which contributes to formation of the apoplastic barrier.[RCN1] (Mus musculus) PubMed

 14558.

The Cdo mRNA level increased gradually 2.5-4.5 h after exposure of the mycelium to l-cystine. [Cdo] (Mus musculus) PubMed

 14559.

The effects of androgen blockade on the expression of 3beta-hydroxysteroid dehydrogenase (3beta-HSD), CYP17, and 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) in the porcine fetus are reported.[17beta-HSD1; CYP17] (Mus musculus) PubMed

 14560.

Data regarding small molecule/ligand binding sites suggest that residues lining substrate access pathways to active site in MoFe/nifD are generally conserved among species. [nifD, molybdoferredoxin] (Mus musculus) PubMed

 14561.

structure and activities of Helicobacter pylori neutrophil-activating protein (Mus musculus) PubMed

 14562.

this study demonstrates that HIV-1 gp120 is able to inhibit neuronal nitric oxide synthase through a cytosolic phospholipase A2 -dependent arachidonic acid production, this response being critical for allowing activation of the transcriptional factor NF-kappaB and subsequent iNOS and interleukin-1beta transcription in astroglial cells. [ HIV-1 gp120 ] (Mus musculus) PubMed

 14563.

Thus, yakA is required for normal patterns of development, cell wall integrity, chitin deposition, appropriate chs expression and heat stress response in Penicillium marneffei.[YakA] (Mus musculus) PubMed

 14564.

These data indicate that the TrpA protein is part of the outer sheath of this organism.[TrpA] (Mus musculus) PubMed

 14565.

Data suggest substitution of hydrophobic residues along helix face in dmsD (dimethyl sulfoxide reductase, subunit D) reduces affinity for leader peptide of dmsA. [dmsD; twin-arginine leader-binding protein; dimethyl sulfoxide reductase, subunit D] (Mus musculus) PubMed

 14566.

The most striking phenotype of the multi-HMG-box protein HmbB deletion strains is a dramatic decrease in conidial and ascospore viability.[HmbB] (Mus musculus) PubMed

 14567.

The knockdown of Bub3, Mad2, or Mps1 produces defects in chromosome segregation and nuclear number and positioning in Giardia intestinalis. [Mps1] (Mus musculus) PubMed

 14568.

Csi1p serves as a linking molecule tethering spindle-stabilizing factors such as alp7p to the spindle pole body for promoting bipolar spindle assembly. [Csi1p] (Mus musculus) PubMed

 14569.

The role of GABARAP on apoptosis in chick embryo fibroblasts subjected to prolonged nutrient depletion is reported.[GABARAP] (Mus musculus) PubMed

 14570.

These results suggest that Rbc3alpha modulates synaptic transmission in hair cells by promoting V-ATPase activity in synaptic vesicles. (Mus musculus) PubMed

 14571.

Kir2.3 (Kcnj4) and SAP97 interact in sheep atrial myocardium. (Mus musculus) PubMed

 14572.

AIDA-I is heptosylated within the bacterial cytoplasm by autotransporter adhesin heptosyltransferase (AAH) and its paralogue AAH2. [AIDA-I, AAH, AAH2] (Mus musculus) PubMed

 14573.

HCV core protein and virus assembly: what we know without structures [HCV core protein] (Mus musculus) PubMed

 14574.

Authors show that the NSs protein acts as a weak interferon antagonist in human cells but that it is unable to completely counteract the interferon response, which could serve as an explanation for its inability to cause disease in humans.[NSs] (Mus musculus) PubMed

 14575.

EtgA was structurally characterized in a type III secretion system of enteropathogenic Escherichia coli as a peptidoglycan-lytic enzyme. [EtgA] (Mus musculus) PubMed

 14576.

After merozoite egress from infected erythrocytes, remnant P. falciparum hemolysin III released from digestive vacuoles could potentially contribute to lysis of uninfected erythrocytes to contribute to severe life-threatening anemia. (Mus musculus) PubMed

 14577.

Proteomics analysis in a swine model of acute myocardial infarction identified ENH2 protein as a phosphoprotein predicted for a role as a nodal point in cardiac signaling. [ENH2] (Mus musculus) PubMed

 14578.

A significant increase in TGF-beta1 and CTGF was found at 6 weeks in the subsynovial connective tissue in a rabbit model of carpal tunnel syndrome. [TGF-beta1] (Mus musculus) PubMed

 14579.

results showed that pandemic H1N1 D222N mutants had receptor specificity different from that of wild-type viruses [hemagglutinin] (Mus musculus) PubMed

 14580.

Se14 is a novel photoperiod-sensitivity gene that has a suppressive effect on floral transition (flowering time) under long day-length conditions through the modification of chromatin structure by H3K4me3 demethylation in the promoter region of RFT1. [Se14] (Mus musculus) PubMed

 14581.

Results suggest that the TcZC3H39 protein is part of an ribonucleoprotein complex targeting transcripts to downregulation. {ZC3H39]. (Mus musculus) PubMed

 14582.

demonstrated that orf105/ycf93 from the apicoplast genome encodes a small membrane protein that likely resides in the inner membrane of the apicoplast and undergoes turnover during asexual red blood cell life cycle of the parasite; orthologues occur in all apicoplasts [Ycf93 protein (Orf105)] (Mus musculus) PubMed

 14583.

snxA interacts with the CDK1 mitotic regulatory pathway in Aspergillus nidulans. [snxA] (Mus musculus) PubMed

 14584.

glutathione reductase 3 (GR3) plays an important role in salt stress tolerance by regulating the GSH redox state in rice (GR3). (Mus musculus) PubMed

 14585.

Identification and functional characterization of the O-acetyltransferase encoding gene, oacC, shows that it is involved in O-antigen modification by 3/4-O-acetylation on RhaIII specific to serotype 6.[oacC] (Mus musculus) PubMed

 14586.

Results indicate that CD58 is a novel cell-surface marker that functionally regulates self-renewal of Colorectal tumor-initiating cells. [CD58] (Mus musculus) PubMed

 14587.

Strong inhibition of seedling growth was observed after silencing TaSGT1 but not TaRAR1. In contrast, decreasing the expression of TaRAR1 or TaSGT1 could all compromise R gene mediated resistance to stripe rust fungus infection. [TaRAR1] (Mus musculus) PubMed

 14588.

The ketoreductase domain of the (R)-mellein-synthesizing partially reducing polyketide synthases SACE5532 functions as a B-type KR domain to generate (R)-hydroxyl functionalities. [SACE5532] (Mus musculus) PubMed

 14589.

the tight control of SprA and GlxR availability may indicate their importance in global gene regulation. (Mus musculus) PubMed

 14590.

characterization of the dtxR alleles from 34 isolates of C. diphtheriae recovered from Romanian patients; 3 of the 7 alleles identified have not previously been described; 2 new DtxR types were identified [DtxR] (Mus musculus) PubMed

 14591.

TAL20Xam668 specifically induces the sugar transporter MeSWEET10a to promote virulence. [TAL20Xam668] (Mus musculus) PubMed

 14592.

Our study highlights the distinct and conserved characteristics associated with G protein signaling and contributes to our overall understanding of how G protein a subunits function with or without a canonical Gb partner in C. neoformans. (Mus musculus) PubMed

 14593.

These results identify Upc2 as a major regulator of ascorbic acid-induced effects in C. albicans and suggest an association between ergosterol content and elongated growth upon Hsp90 compromise. (Mus musculus) PubMed

 14594.

These findings indicate that TcOGNT2 downregulation is important for proper differentiation of MCTs and functioning of TCTs and that TcOGNT2 regulates these functions by using both catalytic and noncatalytic mechanisms. (Mus musculus) PubMed

 14595.

Analysis of Boltzmann distribution functions describing the dependence of MscS channel gating on membrane tension indicated that the gating area change (DeltaA) was the same for MscS channels.[MscS] (Mus musculus) PubMed

 14596.

Following bacterial phagocytosis, pneumolysin (PLY) triggers apoptosis and prevents macrophage necrosis as a component of a broad-based antimicrobial strategy.[PLY] (Mus musculus) PubMed

 14597.

Additionally, Rab11 recruitment is absent and Shigella-containing vacuolar rupture is delayed in the ipgD mutant that does not dephosphorylate PI(4,5)P2 into PI(5)P. (Mus musculus) PubMed

 14598.

This study indicates that the R127 mutation in 3A may play an important role in foot-and-mouth disease virus replication in vitro and in pathogenicity in suckling mice. (Mus musculus) PubMed

 14599.

Based on these results and the genetic evidence for the interaction of Ump2 with both Rho1 and Rac1, another small GTPase, we propose a model for the role of these interactions in controlling filamentation (Mus musculus) PubMed

 14600.

The embryonic mir-35 family of microRNAs promotes multiple aspects of fecundity in Caenorhabditis elegans [mir-35] (Mus musculus) PubMed

 14601.

Data suggest that the PilA1 prepilin interferes with the translocon machinery required for the synthesis of pilins and Photosystem II complex. [PilA1] (Mus musculus) PubMed

 14602.

The crystal structures of DacA and DacB were determined and show that DacB's structure differs radically from that of DacA, and contains a mononuclear Zn2+ catalytic centre located in the middle of a large and fully exposed groove. [DacA] & [DacB] (Mus musculus) PubMed

 14603.

Shu1 is a cell-surface protein involved in iron acquisition from heme in Schizosaccharomyces pombe. [Shu1] (Mus musculus) PubMed

 14604.

Finding show that the ratio of FlaA and FlaB impacts the bacterial motility which decreases with the ratio. [Fla], [FlaB] (Mus musculus) PubMed

 14605.

Phenotype microarray analysis identifies a new peptide transporter A (CptA) shown to participate in the glutathione-derivative Cys-Gly catabolism in Campylobacter jejuni. [CptA] (Mus musculus) PubMed

 14606.

Results identified Asp23 as a membrane-associated protein and we suggest a function for Asp23 in cell envelope homoeostasis. [Asp23] (Mus musculus) PubMed

 14607.

inhibitor of the ICP family is essential for sporozoite motility but also appears to play a role during parasite development in hepatocytes and erythrocytes[cysteine protease inhibitor] (Mus musculus) PubMed

 14608.

Data established that a highly conserved iron importer, FeoB, limits S. Typhimurium replication in macrophages and tissues. [FeoB] (Mus musculus) PubMed

 14609.

Bm67 gene is essential for virus replication.[Bm67] (Mus musculus) PubMed

 14610.

Apr1p is required for morphological transition under nitrogen-limited conditions but not for macrophage killing. [Apr1] (Mus musculus) PubMed

 14611.

As described for other S. aureus nos mutants, inactivation of nos in UAMS-1 conferred sensitivity to oxidative stress, while deletion of pdt did not affect this phenotype.[nos, pdt] (Mus musculus) PubMed

 14612.

3A would interact with membranes through its central hydrophobic region exposing its N- and C- termini to the cytosol, where interactions between viral and cellular proteins required for virus replication are expected to occur.[3A protein] (Mus musculus) PubMed

 14613.

TERT is essential for P. berghei cell survival.[TERT] (Mus musculus) PubMed

 14614.

The crystal structure of group B Streptococcus GAPDH is very similar to those of other GAPDHs, except for a significant difference in the area spanning residues 294-307, which appears to be more acidic. [GAPDH] (Mus musculus) PubMed

 14615.

Crystal structure of the homoserine O-acetyltransferase from Staphylococcus aureus. [Homoserine O-acetyltransferase] (Mus musculus) PubMed

 14616.

The surface levels of three receptors [TfR, epidermal growth factor receptor (EGFR) and beta1 integrin] were tested and found to be reduced dependent on Escherichia coli EspG translocation. (Mus musculus) PubMed

 14617.

Mutations in FT-A1 and FT-B1 delay flowering in tetraploid wheat(FT-A1 and FT-B1). (Mus musculus) PubMed

 14618.

Compared to the wild-type, 1161 genes were differentially expressed in the q mutant. Of these modulated genes, 62.4% (725 genes) were upregulated and 37.6% (436 genes) were downregulated in the q mutant. Q. (Mus musculus) PubMed

 14619.

Downregulation of FT1 by RNAi downregulated FT2 and FT4. Overexpression of FT1 caused early flowering during shoot regeneration. FT1 plays a critical role in the regulation of flowering. FT1. (Mus musculus) PubMed

 14620.

The regulons of the Cjj81176_1484 histidine kinase and the Cjj81176_1483 response regulator contain many common genes, suggesting that these proteins likely form a cognate two-component regulatory system.[Cjj81176_1484, Cjj81176_1483] (Mus musculus) PubMed

 14621.

Deletion of sbp2' attenuated the virulence in a zebrafish model as shown by more than an eightfold increase in the LD50 of Deltasbp2', compared with that of the parent strain.[sbp2] (Mus musculus) PubMed

 14622.

In contrast to previous assumptions, tadpoles possess intact antiviral defenses reliant on type III interferons, which are overcome by frog virus 3 pathogens.[type III interferon] (Mus musculus) PubMed

 14623.

These results suggest that BipA is important for the correct and efficient assembly of the 50S subunit of the ribosome at low temperature but when unmodified by RluC, the ribosomes become BipA independent for assembly.[BipA] (Mus musculus) PubMed

 14624.

Authors show that spontaneous acapsular mutants isolated in vitro harbor mostly nonrevertible single nucleotide polymorphism (SNP) null mutations in cpsE, encoding the initiating glycosyltransferase.[cpsE] (Mus musculus) PubMed

 14625.

RNA annealing and strand displacement activities found in archaeal RNase P proteins are prevalent in eubacterial (C5) and eukaryotic (Rpr2) RNase P proteins [C5] (Mus musculus) PubMed

 14626.

The prevalence of spgM, rmlA, and rpfF genes was 83.3%, 87.5%, and 50.0% in 24 S. maltophilia strains, respectively, and the presence of rmlA, spgM or rpfF had a close relationship with biofilm formation.[spgM, rpfF, rmlA] (Mus musculus) PubMed

 14627.

In contrast to the human PC2, the sea urchinPC2 contains two cooperative Ca2+-binding sites within its EF-hand domain. [PC2] (Mus musculus) PubMed

 14628.

The dense granule protein GRA2 folds intrinsically as an alpha-helix.[GRA2] (Mus musculus) PubMed

 14629.

A novel domain 'GATE' is identified in the DrrA protein.This domain is involved in ATP catalysis.[Drra] (Mus musculus) PubMed

 14630.

important role of F217 in the strict NADPH-dependency, as well as its involvement in the unique catalytic properties of AKR1C33 (aldo-keto reductase 1C33) (Mus musculus) PubMed

 14631.

HCPro did not colocalize with actin filaments or Golgi apparatus. Despite its association with microtubule (MT), the network integrity was required neither for HCPro suppression of silencing nor for its mediation of virus transmission by aphids. [HCPro] (Mus musculus) PubMed

 14632.

PSR2 is a conserved Phytophthora effector family that performs important virulence functions specifically during Phytophthora infection of various plant hosts. [PSR2] (Mus musculus) PubMed

 14633.

The study showed a high incidence of strains with increased virulence, possessing cagA, vacAs1 and iceA1 genes in symptomatic children with H. pylori infection. (Mus musculus) PubMed

 14634.

These findings revealed a novel role of Candida albicans Cfl1 in maintenance of cell wall integrity, mitochondrial function, and interaction between this pathogen and the host.[Cfl1] (Mus musculus) PubMed

 14635.

The membrane-associated proteins FCHO1 and SGIP1 are allosteric activators of the AP2 clathrin adaptor complex. [SGIP1] (Mus musculus) PubMed

 14636.

Acyl-CoA oxidase complexes of Acox-1a, Acox-2, and Acox-3 control the chemical message produced by Caenorhabditis elegans [Acox2 and Acox3] (Mus musculus) PubMed

 14637.

structural analysis of TtPheRS interacting with puromycin and its implications for posttransfer editing reactions [PheR] (Mus musculus) PubMed

 14638.

Data show that parallel evolution of structured and disordered dihydrofolate reductases (DHFR) afforded comparable increases in activity without substantially changing the dynamic properties of the starting scaffolds: [DHFR] (Mus musculus) PubMed

 14639.

Iron/zinc supplementation and depletion experiments suggest that ZIPCO is required for parasite utilization of iron and possibly zinc, consistent with its predicted function as a metal transporter.[ZIPCO] (Mus musculus) PubMed

 14640.

Here the authors show that on secretory vesicles SEC2 mRNA is physically associated with Sec2p.[Sec2p] (Mus musculus) PubMed

 14641.

mutant Escherichia coli protein L25 unable to bind to 5S rRNA are incorporated efficiently into the ribosome [L25] (Mus musculus) PubMed

 14642.

Escherichia coli rpsB promoter activity and regulation [rpsB] (Mus musculus) PubMed

 14643.

In pancreatic intraepithelial lesions, V0a3 subunits localized to the basolateral domain in specific regions. Blocking the v-ATPase disrupted Wnt/beta-catenin signaling in primary PanIN cells. ATP6v0a3. (Mus musculus) PubMed

 14644.

Monophasic expression of the FliC does not affect the ability of 4,[5],12:i:- isolates to adhere porcine intestinal epithelial cells.[FliC] (Mus musculus) PubMed

 14645.

Using homologies studies, the authors identified a new protein in Hydra vulgaris named SYCP2 because it belongs to synaptonemal complex which was already present in the common ancestor of metazoans more than 500 million years ago. [SYCP2} (Mus musculus) PubMed

 14646.

LjALD1 may play important roles in plant development and nodulation via salicylic acid signaling in L. japonicus.[LjALD1] (Mus musculus) PubMed

 14647.

Data suggest that Pru p 1 is the major offending allergen from Prunus persica in 12 northern Italian patients with food hypersensitivity to peaches and seasonal allergic rhinitis. [Pru p 1; allergen Pru p 1] (Mus musculus) PubMed

 14648.

Erg25A and erg25B catalyse ergosterol intermediate demethylation and involve in the fungal stress response.[erg25A, erg25B] (Mus musculus) PubMed

 14649.

By in situ hybridization we revealed expression of rai1 in the developing craniofacial tissues and the nervous system. Knockdown of Rai1 using antisense morpholinos resulted in defects in the developing brain and face. (Rai1 protein) (Mus musculus) PubMed

 14650.

A xyloglucan-specific endo-1,4beta-glucanase (XcXGHA) from Xanthomonas citri pv. mangiferaeindicae has been cloned, expressed in Escherichia coli, purified and characterised.[XGHA] (Mus musculus) PubMed

 14651.

Thus, ClfA recruitment of serum ApoE to the Staphylococcus aureus surface may sequester ApoE and blunt its host defence function against Staphylococcus aureus-invasive infections to humans.[ClfA] (Mus musculus) PubMed

 14652.

The AceK enables opposite kinase and phosphatase activities with Asp477 and a single Mg(2+) ion.(AceK protein, E coli) (Mus musculus) PubMed

 14653.

This study demonstrates that the IncX backbone is a flexible platform that has contributed to qnrS1 dissemination in Nigeria.[qnrS1] (Mus musculus) PubMed

 14654.

R3a and R3a* provide resistance to P. infestans isolates expressing AVR3aKI but not those homozygous for AVR3aEM. [AVR3a] (Mus musculus) PubMed

 14655.

R3a and R3a* provide resistance to P. infestans isolates expressing AVR3aKI but not those homozygous for AVR3aEM.[R3a] (Mus musculus) PubMed

 14656.

Results on transgenic zebrafish show that Ct74a is located within the HoxB cluster adjacent to Hoxb4a and is expressed in a Hoxb4a-like pattern in the hindbrain and pharyngeal arches. [Ct74a] (Mus musculus) PubMed

 14657.

Hel45 is present in mRNA ribonucleoprotein complexes that are not associated with polysomes in Trypanosoma cruzi. [Hel45] (Mus musculus) PubMed

 14658.

Thus, Pet1p and Pet2p are likely involved in transporting phosphoenolpyruvate from the cytoplasm into the Golgi.[Pet1p, Pet2p] (Mus musculus) PubMed

 14659.

MtrA is required for conidial viability, normal fungal growth and development, and virulence. [mtrA] (Mus musculus) PubMed

 14660.

Deletion of the kaiAB1C1 gene cluster causes impaired cell growth under light-dark conditions.[kaiA, kaiB1, kaiC1] (Mus musculus) PubMed

 14661.

These findings reveal a novel pathway whereby Helicobacter pylori CagL, via interaction with host integrins, can trigger pro-inflammatory responses independently of CagA translocation or NOD1 signalling.[CagA, CagL] (Mus musculus) PubMed

 14662.

Authors show that Hsp90 function is required in both insect and mammalian life stages and that the Sti1-binding motif of Hsp90 is crucial for proliferation of insect and mammalian stages of the parasite.[Hsp90] (Mus musculus) PubMed

 14663.

CsiV, a small periplasmic protein with no previously described function, is essential for growth in the presence of D-amino acids. [CsiV] (Mus musculus) PubMed

 14664.

Light-induced conformational changes, observed in the monomeric case, play a decisive role in controlling the dimerization tendency of Vivid with its partner domains. [Vivid] (Mus musculus) PubMed

 14665.

Nucleoid compaction by MrgA in itself is insufficient for oxidative stress resistance, and Asp56 and Glu60 constitute essential molecular sites in MrgA for oxidative stress resistance and survival against phagocytic killing.[MrgA] (Mus musculus) PubMed

 14666.

The transition-state analogue affinity and thermodynamics in mutant VcMTAN became even more unlike those of EcMTAN, the opposite of expectations from catalytic site similarity (Mus musculus) PubMed

 14667.

R9a confers resistance to late blight [R9a] (Mus musculus) PubMed

 14668.

IFI16 and cGAS cooperate in a novel way to sense nuclear herpesviral DNA and initiate innate signaling [IFI16] (Mus musculus) PubMed

 14669.

an evolutionarily conserved regulatory axis links metabolic respiration and AMPK to Ire1p, which regulates a differentiation response involving the modulated activity of ERK and p38 MAPK pathways. (Mus musculus) PubMed

 14670.

Med2 paralogs encoding Mediator subunits regulate different virulence properties in Candida spp. and their expansion may account for the increased adaptability of C. albicans relative to other Candida species. (Mus musculus) PubMed

 14671.

The analysis of transgenic rice lines over-expressing the OsUGE1 show that the gene plays an important role in cell wall carbon partitioning during adaptation to nitrogen-limiting conditions. [UGE1] (Mus musculus) PubMed

 14672.

Increased expression of miR-15b in diabetic wounds in response to injury may, in part, be responsible for the abnormal angiogenic response seen in diabetic wounds and may contribute to the observed wound healing impairment. (Mus musculus) PubMed

 14673.

ribosomal A-site, S12 protein mutations and paromomycin binding [S12] (Mus musculus) PubMed

 14674.

two additional triplets necessary for the suppressor function of the 2b protein [2b protein] (Mus musculus) PubMed

 14675.

These data are the first step in understanding the epigenetic mechanism of alcohol toxicity in early pre-implantation mouse embryos, based on the acetylation of H3K9.[H3K9] (Mus musculus) PubMed

 14676.

Amphipathic helix in M2 protein confers the ability to cause high membrane curvature and directs the protein to this high-curvature domain.High-curvature phase is associated with virus budding.[M2 protein] (Mus musculus) PubMed

 14677.

However, expression of tleA conferred the capacity for adherence to nonadherent E. coli HB101.[tleA] (Mus musculus) PubMed

 14678.

Authors identified the ibeA gene in the genome of adherent-invasive Escherichia coli strain NRG857c and report the contribution of IbeA to the interaction of AIEC with IECs and macrophages and colonization of the mouse intestine.[IbeA] (Mus musculus) PubMed

 14679.

Taken together, these data demonstrate that the CpxRA two-component signal transduction system is essential for the in vivo virulence of Citrobacter rodentium.[CpxRA] (Mus musculus) PubMed

 14680.

Electrostatic occlusion and quaternary structural ion pairing are key determinants of Cu(I)-mediated allostery in the copper-sensing operon repressor (CsoR). (Mus musculus) PubMed

 14681.

a unique medaka fish mutant, hirame (hir), is sensitive to deformation by gravity: hir embryos display a markedly flattened body caused by mutation of YAP, a nuclear executor of Hippo signalling that regulates organ size [YAP] (Mus musculus) PubMed

 14682.

Cdc13A and cdc13B proteins have achieved highly tailored, species-specific binding to the cognate telomere repeat unit by forming heterodimers and by utilizing a combinatorial mechanism of recognition (Cdc13A and cdc13B). (Mus musculus) PubMed

 14683.

Collectively, Trichomonas vaginalis GP63 metallopeptidase induces host cell mTOR cleavage, which may be related to survival of the parasite.[GP63 metallopeptidase] (Mus musculus) PubMed

 14684.

Rac1 regulates polarized growth and pathogenicity by interacting with its effector Cla4 in Verticillium dahlia (Rac1). (Mus musculus) PubMed

 14685.

The structures of eight alkyl benzenes, in single-methylene increases from benzene to n-hexylbenzene, bound to an enclosed cavity in T4 lysozyme, is reported.[Lysozyme] (Mus musculus) PubMed

 14686.

The structures of an amino acid ABC importer Art(QN)2 from Thermoanaerobacter tengcongensis, are reported.[ArtQ, ArtN] (Mus musculus) PubMed

 14687.

A previously orphanized receptor tyrosine kinase (RTK) from A. aegypti encoded by the gene AAEL001915 is an ovary ecdysteroidogenic hormone receptor.[AAEL001915] (Mus musculus) PubMed

 14688.

X-ray crystal structures of a Streptococcus Rgg protein alone and in complex with a tight-binding signaling antagonist, the cyclic undecapeptide cyclosporin A, is reported.[Rgg2] (Mus musculus) PubMed

 14689.

The common pathway intermediate produced by PvcA is directed toward different ultimate products by PvcB, a member of the family of Fe(2+), alpha-ketoglutarate-dependent oxygenases. (Mus musculus) PubMed

 14690.

Cryptococcus neoformans Yap1 is an important genetic determinant of fluconazole resistance in C. neoformans that encodes a basic region-leucine zipper transcription factor homologous to Saccharomyces cerevisiae Yap1 (Yap1). (Mus musculus) PubMed

 14691.

In the absence of RecFOR and XerS, dimers persist, as confirmed by DAPI staining, and can limit the efficiency of transformation, since resulting in loss of transformant chromosome (Mus musculus) PubMed

 14692.

This study evaluated the effects of feed additives on diarrhea and fecal shedding of F4ac fimbrium (fae) and heat-stable toxin (est-II)in piglets.(fae; est-II) (Mus musculus) PubMed

 14693.

Sm29 antigen is able to activate regulatory monocyte-derived dendritic cells in patients with cutaneous leishmaniasis.[Sm29] (Mus musculus) PubMed

 14694.

role in nutritional homeostasis [Ilp-1] (Mus musculus) PubMed

 14695.

PTIP promotes double-strand break repair through a direct role in homologous recombination.[PTIP] (Mus musculus) PubMed

 14696.

Although a heterogenous array of mprF SNPs were often found in daptomycin-sensitive methicillin-resistant Staphylococcus aureus strains, only selected hot spot SNPs were associated with the daptomycin-resistant phenotype. [mprF] (Mus musculus) PubMed

 14697.

Photochemical chromophore isomerization in histidine kinase rhodopsin HKR1. (Mus musculus) PubMed

 14698.

our data indicate that BCL7B/BCL-7 has some roles in maintaining the structure of nuclei and is involved in the modulation of multiple pathways, including Wnt and apoptosis (Mus musculus) PubMed

 14699.

evidence for the existence of a functional link between TEP1 and activation of hemolymph prophenoloxidase during systemic infections. (Mus musculus) PubMed

 14700.

Expression of CYP3A7 in the liver is developmentally regulated, with higher levels before birth than after. Expression is primarily regulated by glucocorticoids and the glucocorticoid receptor. (Mus musculus) PubMed

 14701.

Dbp2 is a key integrator of nutritional status and gene expression programs required for energy homeostasis.[Dbp2] (Mus musculus) PubMed

 14702.

the genetic requirements for MOP1, MOP2, and MOP3 for endogenous gene silencing, were investigated.[MOP1, MOP2, MOP3] (Mus musculus) PubMed

 14703.

These data strongly support a role for EspG1/G2 and its associated effects on microtubules in delaying the recovery of damaged tight junctions caused by enteropathogenic Escherichia coli infection.[EspG1, EspG2] (Mus musculus) PubMed

 14704.

Pbp2x localizes separately from Pbp2b during later stages of cell division. [Pbp2x, Pbp2b] (Mus musculus) PubMed

 14705.

RpS3 by excess nuclear Ltv1 interferes with 40S function or with a nonribosomal function of RpS3.[Ltv1] (Mus musculus) PubMed

 14706.

These results indicate that equine herpesvirus type 1 gC can bind equine red blood cells irrespective of heparin, in contrast to other herpesvirus gC proteins. (Mus musculus) PubMed

 14707.

intracellular RpoS dosage is central to a sigmoidal, saturable three- to fourfold increase in mutation rates and associated changes in DNA repair proteins.[RpoS] (Mus musculus) PubMed

 14708.

complexation with polysaccharides is rate-limiting for ChiA [ChiA] (Mus musculus) PubMed

 14709.

Distribution of the Ppd-A1 haplogroups and haplotypes in wheat species, and their geographical distributions were analysed.[Ppd-A1] (Mus musculus) PubMed

 14710.

Rice SNAC1 gene may have a role in drought resistance. (Mus musculus) PubMed

 14711.

A gene coding for a nerolidol/linalool (NES/LINS) synthase was evaluated in the role of linalool biosynthesis in grape berries.[VvRILinNer] (Mus musculus) PubMed

 14712.

the LBP gene is involved in the acute-phase immunologic response to the bacterial infections.[LBP] (Mus musculus) PubMed

 14713.

Authors show that the ATP-dependent Lon protease plays an important role in regulating the expression of RamA and therefore multidrug resistance via AcrAB-TolC in Salmonella typhimurium. (Mus musculus) PubMed

 14714.

a monomeric acid phosphatase (ACP) with a molecular mass of 72.5 kDa was purified from fruiting bodies of cultured Schizophyllum commune and characterized [ACP} (Mus musculus) PubMed

 14715.

Lpf1 and Lpf2 are important bacterial virulence factors that might be involved in the inflammatory responses associated with enterohemorrhagic E. coli infections. [Lpf1,Lpf2] (Mus musculus) PubMed

 14716.

the C-terminal domains of neurofibromin, Ira1, and Ira2 regulate the metaphase to anaphase transition in a Mad2-independent fashion.[ira1, Ira2] (Mus musculus) PubMed

 14717.

These findings indicate that DDX5 positively regulates the replication of porcine reproductive and respiratory syndrome virus via its interaction with viral Nsp9 in vitro.[Nsp9] (Mus musculus) PubMed

 14718.

FlgS interact with a peptide consisting of residues 1 to 25 of FlhA with high affinity. [FlgS] (Mus musculus) PubMed

 14719.

TaSCL14 may act as a multifunctional regulator involved in plant growth, photosynthesis, tolerance to photooxidative stress, and senescence. [TaSCL14] (Mus musculus) PubMed

 14720.

FarR and FarE are regulator and effector of linoleic acid and arachidonic acids resistance.[FarR and FarE ] (Mus musculus) PubMed

 14721.

DSS1 mediates growth and stress responses in rice.[DSS1] (Mus musculus) PubMed

 14722.

CPB1 of Aedes aegypti interacts with Dengue virus 2 E protein and regulates intracellular viral accumulation. [CPB1] (Mus musculus) PubMed

 14723.

These results indicate that phyB is involved in light-dependent and tissue-specific repression of the PHYA gene in rice.[PHYA, PHYB] (Mus musculus) PubMed

 14724.

E. coli cells overexpressing the yciW gene, a novel Cys regulon, accumulated l-homocysteine, suggesting that YciW is involved in L-methionine biosynthesis [yciW] (Mus musculus) PubMed

 14725.

ScpA, SspA, and SspB limit biofilm formation.[ScpA, and SspB (Mus musculus) PubMed

 14726.

O157:H7-induced IL-1beta production was largely dependent upon caspase-1 activation and partially dependent upon ATP signalling and cathepsin B release, which were both involved in NLRP3 activation. (Mus musculus) PubMed

 14727.

qPC1 in rice controls grain protein content (GPC) by regulating the synthesis and accumulation of proteins and starch. qPC1 encodes a putative amino acid transporter OsAAP6, which functions as a positive regulator of GPC in rice. (Mus musculus) PubMed

 14728.

TibC harbors a heptosyltransferase activity on TibA and AIDA-I.[TibC, TibA] (Mus musculus) PubMed

 14729.

the essential requirement for ESA1 in Saccharomyces cerevisiae can be bypassed upon loss of Sds3, a noncatalytic subunit of the Rpd3L deacetylase complex.[ESA1] (Mus musculus) PubMed

 14730.

ZFP36 is required for abscisic acid (ABA)-induced antioxidant defense, for the tolerance of rice plants to water stress and oxidative stress, and for the regulation of the cross-talk between NADPH oxidase, HO, and MAPK in ABA signaling (ZFP36). (Mus musculus) PubMed

 14731.

The toxa strains were unable to induce necrosis on ToxA-sensitive wheat genotypes.[ToxA] (Mus musculus) PubMed

 14732.

Authors demonstrate that gene JHP0940 can be secreted by the bacteria, triggers apoptosis in cultured mouse macrophages and acts as an auto-phosphorylating tyrosine kinase.[JHP0940] (Mus musculus) PubMed

 14733.

A transcriptional regulator Sll0794 regulates tolerance to biofuel ethanol in photosynthetic Synechocystis sp. PCC 6803. [Sll0794] (Mus musculus) PubMed

 14734.

H. pylori CagA acts as a pathogenic scaffold protein that induces a Snail-mediated epithelial-mesenchymal transition via the depletion of GSK-3. (Mus musculus) PubMed

 14735.

Hence, the present study reveals an unanticipated role for SopE and SopE2 in establishing the Salmonella replicative niche, and further emphasizes the importance of entry effectors in later stages of host-cell manipulation.[SopE] (Mus musculus) PubMed

 14736.

These results shed new light on the structural basis of OsGBSS1 activity and the mechanisms of OsGBSS1 activity on amylose synthesis in vivo.[OsGBSS1] (Mus musculus) PubMed

 14737.

the functional conservation of the sporopollenin-associated gene MALE STERILTY 2 (which is essential for pollen wall development in Arabidopsis thaliana) in the bryophyte Physcomitrella patens, was examined.[MS-2] (Mus musculus) PubMed

 14738.

Msh4 and Msh5 are required for normal chiasma formation.[MSH4, MSH5] (Mus musculus) PubMed

 14739.

AQP2 mediates high-affinity uptake of pentamidine and melaminophenyl arsenicals in trypanosomes and TbAQP2 encodes the previously reported high-affinity pentamidine transporter activity.[AQP2] (Mus musculus) PubMed

 14740.

manganese transport protein C (MntC) is an extracellular matrix- and plasminogen-binding protein [MntC] (Mus musculus) PubMed

 14741.

A combination of mitochondrial cooperation and oxygen photoreduction downstream of PSI (Mehler reactions) supplies extra ATP for photosynthesis in the pgrl1 mutant, resulting in normal biomass productivity under steady state conditions. (Mus musculus) PubMed

 14742.

HSF1 is critical for pathogenicity in P. sojae by detoxifying the plant oxidative burst.[HSF1] (Mus musculus) PubMed

 14743.

These suggest a key role of kinesin-12 as a modulator of axonal development.[Kinesin 12] (Mus musculus) PubMed

 14744.

Hfq controls the production and perception of quorum sensing signals via interactions with expR. [expR, Hfq] (Mus musculus) PubMed

 14745.

The ubiquitin ligase Rsp5 and the glucose-regulated arrestin-related trafficking adaptors (ART) protein Rod1 are also required for the post-endocytic sorting of Jen1 to the yeast lysosome.[Rsp5, Rod1] (Mus musculus) PubMed

 14746.

description of selective autophagy of the endoplasmic reticulum and nucleus in the yeast Saccharomyces cerevisiae; identification of two novel proteins, Atg39 and Atg40, as receptors specific to these pathways [atg39 & atg40] (Mus musculus) PubMed

 14747.

Gp32 plays both positive and negative roles in regulating Dda helicase activity, and that both effects may influence the outcome of complex DNA transactions such as replication fork restart (GP32). (Mus musculus) PubMed

 14748.

As it has been found the substitutions appeared in the HA2 of m4G(10) and m4G(6) viruses compensated negative effect of the S145P1 mutation and provided a significant increase in the viral replication ability (Mus musculus) PubMed

 14749.

These results indicated that higher gene expression of 1-FEH w3 and 1-FEH w3 mediated enzyme activities that favoured stem water-soluble carbohydrate remobilization to the grains.[1-FEH w3] (Mus musculus) PubMed

 14750.

These results reveal two distinct functions of Galpha in NaCl stress in maize and rice: attenuation of leaf senescence caused by sodium toxicity in leaves, and cell cycle regulation by osmotic/ionic stress.[Galpha] (Mus musculus) PubMed

 14751.

These results reveal two distinct functions of Galpha in NaCl stress in maize and rice: attenuation of leaf senescence caused by sodium toxicity in leaves, and cell cycle regulation by osmotic/ionic stress.[Galpha] (Mus musculus) PubMed

 14752.

RsrA primarily operates through NapA-mediated stress response pathways.[RsrA, NapA] (Mus musculus) PubMed

 14753.

crystal structure of Bmlp6 protein [Bmlp6] (Mus musculus) PubMed

 14754.

Nix is both required and sufficient to initiate male development.[Nix] (Mus musculus) PubMed

 14755.

RsrA primarily operates through NapA-mediated stress response pathways.[RsrA, NapA] (Mus musculus) PubMed

 14756.

RsrA primarily operates through NapA-mediated stress response pathways.[RsrA, NapA] (Mus musculus) PubMed

 14757.

seed traits were affected by the interaction of JcARF19 and JcIAA9.[JcARF19 and JcIAA9] (Mus musculus) PubMed

 14758.

The presence of a transposon in the upstream of TaMATE1-4B in Barbela 7/72/92 seems to be responsible for its higher transcript expression where it may confer citrate efflux. [TaMATE1] (Mus musculus) PubMed

 14759.

this study identified and characterized Alma1, a DMSP lyase from the bloom-forming algae Emiliania huxleyi. [Alma1] (Mus musculus) PubMed

 14760.

slr1609 was cloned; this gene was shown to possess a fatty acyl-CoA synthetase activity and is located in both the cell membrane and the cytosol [slr1609] (Mus musculus) PubMed

 14761.

Flagellar basal body that either positively or negatively affect expression of RpoN-and FliA dependent flagellar genes.[RpoN, FliA] (Mus musculus) PubMed

 14762.

An essential role of chloroplast pyruvate dehydrogenase complex in the supply of carbon precursors for de novo fatty acid synthesis in microalgae under conditions of photoautotrophy.[E1 alpha] (Mus musculus) PubMed

 14763.

expression patterns of DGK isozymes in developing mouse brain [DGK etha][DGK delta] (Mus musculus) PubMed

 14764.

methionine sulfoxide reductase a exploits a unique mycothiol redox relay mechanism [methionine sulfoxide reductase] (Mus musculus) PubMed

 14765.

Mlp2 in L. major is essentially intranuclear and that its localization is cell cycle-dependent (Mlp2). (Mus musculus) PubMed

 14766.

The autophagy protein Atg8 does not participate in the degradative function in malaria parasites, but rather in apicoplast biogenesis. [Atg8] (Mus musculus) PubMed

 14767.

Overexpression of one stress-responsive gene, OsDi19-4, in rice resulted in significantly increased tolerance to drought stress compared with the wild type plants.[OsDi19-4] (Mus musculus) PubMed

 14768.

Mlp2 in T. brucei is essentially intranuclear and that its localization is cell cycle-dependent (Mlp2). (Mus musculus) PubMed

 14769.

Deltasir2 strains failed to neutralize plant-derived reactive oxygen species and elicited robust defence responses. {Sir2] (Mus musculus) PubMed

 14770.

The role of PfHRPII aspartate carboxylate-heme metal ionic interactions in heme binding and beta-hematin formation.[HRP-2] (Mus musculus) PubMed

 14771.

The study reports the crystal structures of the inducer-binding domain of PcpR in the apo-form and binary complexes with pentachlorophenol (PCP) and 2,4,6-trichlorophenol (2,4,6-TCP). [PcpR] (Mus musculus) PubMed

 14772.

Transcript abundance of PxPAPa and PxPAPb, encoding possible prophenoloxidase-activating proteases (PAP), are increased by microbial challenges (PxPAPa and PxPAPb). (Mus musculus) PubMed

 14773.

Study demonstrates that miR-199a-5p regulates expression of metastasis-related genes in B16F10 melanoma cells. (Mus musculus) PubMed

 14774.

The review summarizes the identification and characterization of MPIase (membrane protein integrase) from Escherichia coli. [MPIase] [review] (Mus musculus) PubMed

 14775.

This is consistent with the hypothesis that ArlRS may play an important role in regulating biofilm formation by the ica(+)aap(+)/BF(-)S. epidermidis clinical isolates and operate via both ica-dependent and Aap-dependent pathways.[ArlA, ArlS] (Mus musculus) PubMed

 14776.

we describe the new bacterial laccase CgL1 from Corynebacterium glutamicum. (Mus musculus) PubMed

 14777.

SmeD,SmeE and SmeF are involved in the endophytic colonization of plant roots. [SmeD,SmeE,SmeF] (Mus musculus) PubMed

 14778.

These results suggest that, under heat stress, abscissic acid triggers the expression of HSP70 in an apoplastic hydrogen peroxide -dependent manner.[HSP70] (Mus musculus) PubMed

 14779.

results indicate that Cnm is the major mediator of extracellular matrix binding and intracellular invasion of HCAEC, and that strains expressing Cnm are potentially better armed to infect non-oral sites of the human host [Cnm] (Mus musculus) PubMed

 14780.

the interaction between Alfalfa mosaic virus (AMV) MP and Arabidopsis Patellin 3 (atPATL3) and Patellin 6 (atPATL6), is reported.[MP] (Mus musculus) PubMed

 14781.

Two mutants (tri6Delta and noxABDelta) of the fungal pathogen Fusarium graminearum were assessed for their ability to prime immune responses in wheat (cv. Roblin) against challenge with pathogenic F. graminearum.[tri6, noxAB] (Mus musculus) PubMed

 14782.

It was found that methionine gamma-lyase catalyzes the beta-elimination reaction of alliin to form 2-propenethiosulfinate (allicin), pyruvate and ammonia. [methionine gamma-lyase] (Mus musculus) PubMed

 14783.

[vcrd1] VcrD1 plays a role in flagellar morphogenesis in V. parahaemolyticus by regulating the expression and secretion of flagellar components. (Mus musculus) PubMed

 14784.

Hemadsorption assay with sialyl linkage-modified red blood cells indicated that amino acid residues at positions 275, 277, 372, and 426 contribute to alpha2,6-linked sialic acid recognition of the HN3 glycoprotein. (Mus musculus) PubMed

 14785.

Trpac1, a pH response transcription regulator, is involved in growth and development process and cellulase gene expression. (Trpac1) (Mus musculus) PubMed

 14786.

Overexpression of TaABL1 enhanced responses of transgenic plants to abscissic acid and hastened stomatal closure under stress, thereby improving tolerance to multiple abiotic stresses.[TaABL1] (Mus musculus) PubMed

 14787.

Here inositol polyphosphate 1-phosphatase has been biochemically identified and its crystal structure has been determined in the presence of Mg(2+) and PO4(3-) at 2.5 A resolution. [inositol polyphosphate 1-phosphatase] (Mus musculus) PubMed

 14788.

PEM1 and PEM2 are important for the development of the parasite throughout its life cycle.[PEM1 and PEM2] (Mus musculus) PubMed

 14789.

Genetic and functional analyses demonstrate that the CPK18-MPK5 pathway negatively regulates rice immunity and represents a novel regulatory mechanism for the MKK-independent activation of MAPKs in land plants. [CPK18; MPK5] (Mus musculus) PubMed

 14790.

Here, crystal structures of the LRR domains of SERK2 and a D128N SERK2 mutant, expressed as hagfish variable lymphocyte receptor (VLR) fusions, are reported. [SERK2] (Mus musculus) PubMed

 14791.

The tgo expression was especially related to plastidial proteins involved in photoprotection and the thylakoid electrochemical gradient.[TGO] (Mus musculus) PubMed

 14792.

These results indicate that OsOPT7 may be involved in iron transport in rice.[OsOPT7] (Mus musculus) PubMed

 14793.

Protein kinase A signaling and calcium ions are major players in PAF mediated toxicity against Aspergillus niger. (Mus musculus) PubMed

 14794.

These results support the hypothesis that TcCPR4 is required for achieving proper morphology of the vertical pore canals and PCFs that contribute to the assembly of a cuticle that is both lightweight and rigid. (Mus musculus) PubMed

 14795.

Results identified the protein, Kis1, which is required for inner kinetochore formation and Mis6 of the inner kinetochore component required for spindle integrity, suggesting a link between the inner kinetochore and spindle assembly. [Eic1] (Mus musculus) PubMed

 14796.

Results suggest that YdeO is a key regulator of E. coli survival in both acidic and anaerobic conditions. [YdeO] (Mus musculus) PubMed

 14797.

Q56R, F120I and D137V ArsA mutants restored interaction with the quadruple ArsD mutant. Each also interacted with wild type ArsD. ArsA mutations propagate changes in hydrogen bonding and salt bridges to the ArsA-ArsD interface. (Mus musculus) PubMed

 14798.

Outer membrane protein P5 binds human complement regulatory protein factor H directly. {P5] (Mus musculus) PubMed

 14799.

In contrast to structure modeling predictions, solution x-ray scattering studies demonstrate that the CesA8 monomer is a two-domain, elongated structure, with the smaller domain coupling two monomers into a dimer. [CesA8] (Mus musculus) PubMed

 14800.

The rice stripe virus resistant allele of rice STV11 (STV11-R) encodes a sulfotransferase catalysing the conversion of salicylic acid (SA) into sulphonated SA (SSA), whereas the gene product encoded by the susceptible allele STV11-S loses this activity. (Mus musculus) PubMed

 14801.

OsACS2 ACC synthase mediates herbivore-induced ethylene biosynthesis [OsACS2] (Mus musculus) PubMed

 14802.

Regulation of thyrotropin is mediated by tissue-specific glycosylation.[Thyrotropin] (Mus musculus) PubMed

 14803.

A function of SNX27 in regulating beta-amyloid (Abeta) generation by modulating gamma-secretase activity, is reported.[Gamma secretase] (Mus musculus) PubMed

 14804.

The crystal structures of both of the subunits of alkylhydroperoxide reductase, AhpF (57 kDa) and AhpC (21 kDa), have been solved. [AhpC, AhpF] (Mus musculus) PubMed

 14805.

The high-resolution structure of a catalytically inactive mutant (H148G) was solved by X-ray crystallography. [nuclease A] (Mus musculus) PubMed

 14806.

the Pol II flap loop is needed for physical interaction of Pol II with the Pcf11/Clp1 subcomplex of cleavage factor IA (CF IA), which functions in both 3' end processing and Pol II termination.[RPB2] (Mus musculus) PubMed

 14807.

IRE1 has two different modes of action: XBP1/HAC1 is cleaved by IRE1 subunits acting cooperatively within IRE1 oligomers, whereas a single subunit of IRE1 performs regulated IRE1-dependent decay without cooperativity.[Ire1] (Mus musculus) PubMed

 14808.

Yrb2p strikingly accelerates the association of Gsp1p-GTP and nuclear export signal to Xpo1p.[Yrb2, Xpo1] (Mus musculus) PubMed

 14809.

H. pylori Csd4 consists of three domains: an N-terminal D,L-carboxypeptidase domain with a typical carboxypeptidase fold, a central beta-barrel domain with a novel fold and a C-terminal immunoglobulin-like domain. [Csd4] (Mus musculus) PubMed

 14810.

The detailed three-dimensional structure of wild-type Abp, a GH27 beta-L-arabinopyranosidase and its catalytic mutant Abp-D197A with and without a bound L-arabinose product are reported as determined by X-ray crystallography. [Abp] (Mus musculus) PubMed

 14811.

The structure of cytochrome c6C from the mesophilic cyano-bacterium Synechococcus sp. PCC 7002 has been determined at 1.03 A resolution. [cytochrome c6C] (Mus musculus) PubMed

 14812.

Overexpression of OsHMA3 is an efficient way to reduce Cd accumulation in the grain and to enhance Cd tolerance in rice. (Mus musculus) PubMed

 14813.

ABCG2 (ATP-binding cassette sub-family G member 2) ABCG2 has a role in the regulation of gametocyte numbers and in the accumulation of neutral lipids, which are likely important for parasite development in the insect stages of the parasite life cycle. (Mus musculus) PubMed

 14814.

Sequencing indicated that SYP-1620 fungicide resistance was associated with a single point mutation (G143A) in the cytochrome b gene [cytochrome b] (Mus musculus) PubMed

 14815.

The structural and biochemical characterization of xylanase 30A from Clostridium papyro-solvens (CpXyn30A) is presented. [xylanase 30A] (Mus musculus) PubMed

 14816.

Activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO1 or PPO1) were closely related to the development of B. dorsalis during the larval-pupal transition, particularly in the integument.[PO,PPO1] (Mus musculus) PubMed

 14817.

Pot2 is expressed during macronuclear development at the time of new telomere synthesis in Tetrahymena. [Pot2] (Mus musculus) PubMed

 14818.

characterization of Bm17; results show that BM17 was a late protein localized in cytoplasm and nucleus [Bm17] (Mus musculus) PubMed

 14819.

EF8 plays an important role in rice photoperiodic flowering pathway as well as yield potential and chlorophyll biogenesis and will be an important target for rice breeding programs.[EF8] (Mus musculus) PubMed

 14820.

OsPAL06 is a positive regulator in preventing Magnaporthe oryzae infection from roots. It may regulate defense by promoting both phytoalexin accumulation and salicylic acid (SA) signaling. [OsPAL06] (Mus musculus) PubMed

 14821.

The differences in leaf gene transcripts, proteins and metabolite accumulation in gln1.3 and gln1.4 mutants were studied at two key stages of plant development.[gln1.3, gln1.4] (Mus musculus) PubMed

 14822.

host HSP70 is necessary for rice stripe virus infection. [HSP70] (Mus musculus) PubMed

 14823.

aroA and aroB are required for normal virulence in rice and onion, growth in M9 minimal medium and tolerance to UV light, but are dispensable for the production of the phytotoxin toxoflavin. [aroA, aroB] (Mus musculus) PubMed

 14824.

Two sgs3 and one rdr6 alleles led to strong developmental defects and impaired biogenesis of siRNA.[rdr6] (Mus musculus) PubMed

 14825.

The study presents the crystal structure of the SemiSWEET from T. yellowstonii. [Semisweet] (Mus musculus) PubMed

 14826.

loss of the copper exporter encoded by copA led to decreased virulence in pulmonary, intraperitoneal, and intravenous models of infection. Deletion of copA resulted in enhanced macrophage-mediated bacterial clearance in vitro. [copA] (Mus musculus) PubMed

 14827.

upregulated in adult fat body after bacterial challenge [cecropin, attacin C] (Mus musculus) PubMed

 14828.

Klhl31 is a novel modulator of canonical Wnt signaling, important for vertebrate myogenesis [Klhl31] (Mus musculus) PubMed

 14829.

LiaR binds an extended stretch of DNA that extends beyond the proposed canonical consensus sequence suggesting a more complex level of regulatory control of target operons (Liar). (Mus musculus) PubMed

 14830.

Data suggest that a single amino acid (Trp 226) located at very C-terminus of cytoplasmic domain of MgtC prevents MgtC degradation by the FtsH protease; action of regulatory peptide MgtR is not required. [mgtR] (Mus musculus) PubMed

 14831.

These data along with earlier FTIR measurements on the CaChR1 --> P1 transition are consistent with a two-step proton relay mechanism that transfers a proton from Glu-169 to Asp-299 during the primary phototransition (Mus musculus) PubMed

 14832.

CDO, CRY-dependent oscillator, is necessary for the novel oscillator activity in Neurospora (Mus musculus) PubMed

 14833.

Dbf4-dependent protein kinase is required for spontaneous as well as induced Polzeta-dependent mutagenesis. [DDK] (Mus musculus) PubMed

 14834.

We analyzed the expression of genes that function in floral meristems and found that RFL and WOX3 were severely downregulated in sped1-D.[WOX3] (Mus musculus) PubMed

 14835.

Gibberellin receptor GID1L2 family genes were downregulated in the sped1-D mutant. Therefore, treatment of sped1-D plants with gibberellin during panicle initiation did not lead to elongation of secondary branches or pedicels.[GID1L2] (Mus musculus) PubMed

 14836.

kinetics of hydrogen atom abstraction from substrate by an active site thiyl radical in ribonucleotide reductase [RNRIa] (Mus musculus) PubMed

 14837.

these findings reveal why the coordinated activities of HlyA and CNF1 are necessary for the full virulence of uropathogenic Escherichia coli (Mus musculus) PubMed

 14838.

The results invoke a novel RNA regulatory mechanism involving the NMD3-dependent nuclear export of mRNA cargos, suggesting a shared platform for mRNA and rRNA export (NMD3). (Mus musculus) PubMed

 14839.

Authors propose that F55 acts as a molecular switch for the transcriptional regulation of the early viral genes.[F55] (Mus musculus) PubMed

 14840.

Two full-length membrane-bound aminopeptidase N (AaeAPN) isoforms, AaeAPN2778 and AaeAPN2783, predicted to be GPI-linked were cloned and expressed in Sf9 cells as 112- and 107-kDa membrane-bound proteins, respectively. [AaeAPN2778, AaeAPN2783] (Mus musculus) PubMed

 14841.

Overexpressing the splice regulator TgSR3 perturbed alternative splicing in over 1000 genes in Toxoplasma gondii (TgSR3). (Mus musculus) PubMed

 14842.

succeeded in cloning the cDNA of beta-defensin of O. niloticus (designated Onbeta-defensin) and showed that this encoded a 66 amino acid peptide; Onbeta-defensin plays a role in immune responses that suppress or kill pathogens. [Beta-defensin] (Mus musculus) PubMed

 14843.

Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-A resolution. (Mus musculus) PubMed

 14844.

ACT-10, a novel plasmid-encoded class C beta-lactamase in a Serratia marcescens isolate from China.[ACT-10 beta-lactamse] (Mus musculus) PubMed

 14845.

A higher prevalence of miR-UL112-3p was detected in Diabetes Mellitus and Glioblastoma multiforme patients than in Rheumatoid Arthritis patients and Healthy Controls (Mus musculus) PubMed

 14846.

a novel acid-induced virulence factor, HtpA, was demonstrated to improve anti-phagocytosis ability for causing necrotizing fasciitis. (Mus musculus) PubMed

 14847.

NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function. (Mus musculus) PubMed

 14848.

The loss of H5 does not compromise the accumulation of other early viral replication proteins or the uncoating of the virion core, suggesting that H5 plays a direct and essential role in facilitating DNA synthesis.[H5] (Mus musculus) PubMed

 14849.

These results demonstrate that nsp10 is important for murine hepatitis virus replication fidelity and support the hypothesis that nsp10 functions to regulate nsp14-ExoN activity during virus replication.[nsp10] (Mus musculus) PubMed

 14850.

These results identify a PA domain critical for PB1-PA nuclear import.[PA, PB1] (Mus musculus) PubMed

 14851.

The results show that the N-terminal domain of Rpf2 plays a critical role in binding to both 5S rRNA and Rrs1 (Rpf2 and Rrs1). (Mus musculus) PubMed

 14852.

Regulated knockdown of TgCRT expression resulted in modest reduction in parasite fitness and swelling of the VAC, indicating that TgCRT contributes to parasite growth and VAC physiology [CRT] (Mus musculus) PubMed

 14853.

[kaplanhearing@verizon.net] Deletion of the AN10444 gene (ggtA) completely eliminated the gammaGT activity, and the mRNA levels of ggtA showed strong correlation with the observed gammaGT activities (Mus musculus) PubMed

 14854.

GcnE function was found to be required for the acetylation of histone H3K9/K14 at the promoter of the master regulator of conidiation, brlA, as well as at the promoters of the upstream developmental regulators of conidiation luffy genes. [GCN5] (Mus musculus) PubMed

 14855.

gga-miR-1596-3p microRNA was significantly associated with residual feed intake [miRN-1596] (Mus musculus) PubMed

 14856.

The effects of both subunits of a variant SubAB2 shiga toxin in E. coli are reported.[SubAB2] (Mus musculus) PubMed

 14857.

Data from biomolecular nuclear magnetic resonance on TTTA repeats in icaC gene suggest such sequences fold into dumbbell structures with 3-prime or 5-prime-overhang and may participate in DNA repeat expansion. [icaC; intercellular adhesin, subunit C] (Mus musculus) PubMed

 14858.

data indicate that the helical RGD motif in CagL is buried by a neighboring helix at low pH to inhibit CagL binding to integrin, whereas at neutral pH the neighboring helix is displaced to allow integrin access to the CagL RGD motif. (Mus musculus) PubMed

 14859.

A small angle x-ray scattering model of SmTK-TSA in solution with two closed active sites was generated. (Mus musculus) PubMed

 14860.

retinoic acid negatively regulates dact3b in the hindbrain [dact3b] (Mus musculus) PubMed

 14861.

analysis of AcrB remote alternating-access transport mechanisms for protons and substrates [AcrB] (Mus musculus) PubMed

 14862.

Mutations at positions 159, 189 and 227 of HA altered antigenicity. [HA] (Mus musculus) PubMed

 14863.

analysis of Plasmodium class XIV myosin, MyoB, which has a distinct subcellular location in invasive and motile stages of the malaria parasite and an unusual light chain [MyoB] (Mus musculus) PubMed

 14864.

analysis of Plasmodium class XIV myosin, MyoB, which has a distinct subcellular location in invasive and motile stages of the malaria parasite and an unusual light chain [MyoB] (Mus musculus) PubMed

 14865.

analysis of Plasmodium class XIV myosin, MyoB, which has a distinct subcellular location in invasive and motile stages of the malaria parasite and an unusual light chain [MyoB] (Mus musculus) PubMed

 14866.

Group B Streptococcus-beta-haemolysin is solely responsible for gelsolin increase causing, through membrane permeability defects, calcium influx and calpain activation.[beta-haemolysin] (Mus musculus) PubMed

 14867.

NCAPG2 plays an important role in regulating proper chromosome segregation through a functional interaction with PLK1 during mitosis [NCAPG2] (Mus musculus) PubMed

 14868.

Parasites lacking TgSIP are significantly shorter than wild-type parasites and show defects in gliding motility, invasion and reduced infectivity in mice.[TgSIP] (Mus musculus) PubMed

 14869.

an interaction between VER2 and TaGRP2 is mediated by O-GlcNAc and elicits TaVRN1 mRNA accumulation during vernalization [GRP2, VRN1] (Mus musculus) PubMed

 14870.

We propose that the Rim15-Endosulfine( Igo1 and Igo2 )-PP2ACdc55 signalling module triggers entry into quiescence and gametogenesis by regulating dephosphorylation of distinct substrates (Mus musculus) PubMed

 14871.

Escherichia coli DusC is specific toward U16 of tRNA [DusC] (Mus musculus) PubMed

 14872.

The N-terminal extension of iso-1-cytochrome c stabilizes the native WT protein but it has no effect on the stability of pre-molten globule state.[iso-1-cytochrome c] (Mus musculus) PubMed

 14873.

The catalysis rate in Baeyer-Villiger monooxygenase is partially limited by the hydride transfer to flavin. [Baeyer-Villiger monooxygenase ] (Mus musculus) PubMed

 14874.

A novel MS based approach enabling the exact stoichiometric analysis and absolute quantification of protein complexes is presented in this article. The application of this method revealed new insights in RuBisCO subunit dynamics. (Mus musculus) PubMed

 14875.

Eftud2 regulates host defense in C. elegans [Eftud2] (Mus musculus) PubMed

 14876.

Here presented is a density functional theory - based quantum mechanics/molecular mechanics study of NanC Porin in the presence of these anions. [NanC Porin] (Mus musculus) PubMed

 14877.

the newly identified rice CDPK gene OsCPK31 was functionally validated by overexpression and silencing in Taipei 309 rice cultivar.[OsCPK31] (Mus musculus) PubMed

 14878.

findings demonstrated a direct binding between the telomerase-RNA binding domain of TERT and 14-3-3 protein [TERT; 14-3-3 protein] (Mus musculus) PubMed

 14879.

Authors showed that inactivation of wysR resulted in the complete loss of wuyiencin production, which could be restored by complementation with a single copy of wysR.[wysR] (Mus musculus) PubMed

 14880.

Beta-N-acetylhexosaminidase can hydrolyze pNP-GlcNAc, pNP-GalNAc, (GlcNAc)2, (GlcNAc)3, and pNP-(GlcNAc)2. [beta-N-Acetylhexosaminidase] (Mus musculus) PubMed

 14881.

analysis of active site and laminarin binding in glycoside hydrolase family 55 [SacteLam55A, Streptomyces sp. SirexAA-E] (Mus musculus) PubMed

 14882.

OsPT8 plays a critical role in redistribution of P from source to sink organs and P homeostasis in seeds of rice. (Mus musculus) PubMed

 14883.

M298F, V290N and V290A were introduced at or near the T1 copper site of the small laccase. Catalysis with 3 ligands, optimal pH and thermal stability, compared with wild-type were determined. SLAC. (Mus musculus) PubMed

 14884.

FAD-GDH was expressed in E coli, purified, and characterized for substrate specificity, pH, temperature, half-life, and 3-D structure. His551, His508, Asn506 and Arg504 are key residues. Arg84Ala, Tyr340Phe and Tyr406Phe had higher specificity. FAD-GDH. (Mus musculus) PubMed

 14885.

a number of E. faecium strains had PBP5 sequences in between PBP5-S and PBP5-R. These hybrid PBP5-S/R patterns reveal a progression of amino acid changes from the S form to the R form of this protein. [PBP5] (Mus musculus) PubMed

 14886.

The findings suggest that Cas5 regulates a transcriptional network that influences the response of C. albicans to fluconazole. (Mus musculus) PubMed

 14887.

The role of malate dehydrogenase (MDH) and phosphofructokinase (PFK) in the energy metabolism of oocytes during in vitro maturation is reported.[MDH; PFK] (Mus musculus) PubMed

 14888.

In order to increase the thermostability of TRXII, the primary structure of the mesophilic T. reesei xylanase II was compared with those of thermophilics xylanases. (Mus musculus) PubMed

 14889.

Rep initiates leading-strand synthesis and Rep regenerates the parent double-stranded supercoiled genome. [Rep, Rep'] (Mus musculus) PubMed

 14890.

These observations indicate that C-terminus of licC is accounted for the main activity of LicC in Phosphocholine metabolism and is essential for the virulence of Streptococcus pneumoniae.[licC] (Mus musculus) PubMed

 14891.

Our results demonstrate that this lineage-specific evolution of CENH3 causes inviability and sterility of progeny in crosses, at the same time producing karyotypic variation (Mus musculus) PubMed

 14892.

Helicobacter pylori possesses a novel type of intrabacterial nanotransportation systems for VacA. [VacA] (Mus musculus) PubMed

 14893.

CYP105N1 may produce derivatives of coelibactin, which would then be able to chelate the zinc divalent cation. [CYP05N1] (Mus musculus) PubMed

 14894.

two amino mutations present in the ceftaroline-binding pocket of the transpeptidase region of penicillin-binding protein 2a (PBP2a) in ceftaroline-resistant isolates caused ceftaroline resistance. [PBP2a] (Mus musculus) PubMed

 14895.

NorH is the third subunit of the cytochrome c-dependent nitric oxide reductase. [NorH] (Mus musculus) PubMed

 14896.

In silico structural characterization and molecular docking studies of first glucuronoxylan-xylanohydrolase (Xyn30a) from Clostridium thermocellum have been presented. [Xyn30a] (Mus musculus) PubMed

 14897.

crystal structures of PCAT1 from Clostridium thermocellum in two different conformations [PCAT1] (Mus musculus) PubMed

 14898.

Ustilago maydis lipase 2 (Uml2), the product of gene um01422 exhibits not only esterase and lipase activity but also phospholipase A activity.[Uml2] (Mus musculus) PubMed

 14899.

The structures of OPPs from Escherichia coli were solved in the apo-form as well as in complexes with farnesyl pyrophosphate (FPP) and a FPP thio-analog, FsPP, at resolutions of 2.2-2.6 A.[OPP] (Mus musculus) PubMed

 14900.

It was concluded that DNA-directed polymerase subunit gamma 2 is critical for mitochondrial replication and regulation of adenosine-5'-triphosphate content.[POLG2] (Mus musculus) PubMed

 14901.

suilysin assembly is a noncooperative process that is terminated before the protein inserts into the membrane.[Sulysin] (Mus musculus) PubMed

 14902.

ClpB, like ClpA, requires substrates with a minimum length for optimal binding.[ClpB] (Mus musculus) PubMed

 14903.

Novel deletions in Badh2 are associated with fragrance [Badh2] (Mus musculus) PubMed

 14904.

Data (including data from gene deletion studies) suggest that YbeY participates in colonization of intestinal mucosa, biofilm formation, cholera toxin production, and expression of virulence-associated small RNA. [YbeY; endoribonuclease] (Mus musculus) PubMed

 14905.

This study identified ybjE as a gene encoding a predicted inner membrane protein that mediates export of lysine (Lys), and confirms the previous identification with a different approach of YbjE as a Lys exporter.[YbjE] (Mus musculus) PubMed

 14906.

The histidine kinase Vc1319 (VprB) and the response regulator Vc1320 (VprA) respond to environmental signals and are required for the expression of the almEFG operon that encodes the genes essential for glycine modification of lipid A.[VprA, VprB] (Mus musculus) PubMed

 14907.

The study reports the crystal structure of the Staphylococcus aureus ketopantoate reductase (KPR) at 1.8 A resolution, the first description of a dimeric KPR. [ketopantoate reductase] (Mus musculus) PubMed

 14908.

The enzymatic mechanism of Leishmania major peroxidase and the role of specific ionic interactions are presented here. [peroxidase] (Mus musculus) PubMed

 14909.

On the basis of these results, the authors propose that the arginine-ornithine antiporter is essential to maintain pneumococcal fitness and that the genes of the ADS cluster are positively regulated in a strain-specific manner by ArgR2.[Arg2] (Mus musculus) PubMed

 14910.

A 10 amino-acid sequence near the carboxyl end of the C2 domain of PkcA is required for its localization to hyphal tips.[PkcA] (Mus musculus) PubMed

 14911.

The structures of two isolated forms of yeast eIF5B and of the eIF5B-eIF1A complex (eIF1A and eIF5B do not contain the respective N-terminal domains) are reported. [eIF1A] (Mus musculus) PubMed

 14912.

The structures along with electrophoretic mobility shift assays, isothermal titration calorimetry measurements and molecular-dynamics simulations, elucidate the overall and residue-specific changes in HU upon recognizing and binding to DNA. [HU] (Mus musculus) PubMed

 14913.

The 1.3 A resolution crystal structure of the spliceosomal cyclophilin-type peptidyl-prolyl cis-trans isomerase domain of Cwc27 from Chaetomium thermophilum was also determined. [Cwc27] (Mus musculus) PubMed

 14914.

These findings, together with computational data, provide useful insights in the substrate specificity of C-S lyase.[C-S lyase] (Mus musculus) PubMed

 14915.

Clustering facilitates Ire1's cytosolic oligomeric assembly and HAC1 mRNA docking onto a positively charged motif in Ire1's cytosolic linker domain that tethers the kinase/RNase to the transmembrane domain.[Ire1, HAC1] (Mus musculus) PubMed

 14916.

Data suggest that the receptor for porcine Sapovirus Cowden strain in intestinal mucosa is a cell membrane glycoprotein exhibiting both alpha2,3- and alpha2,6-linked sialic acids. [PSaVR, porcine Sapovirus receptor] (Mus musculus) PubMed

 14917.

Data suggest ligand-binding region of sraP (with extended rod-like architecture of four discrete modules) binds to sialylated receptors and promotes adhesion to and invasion of host respiratory mucosal cells. [sraP; serine-rich adhesin for platelets] (Mus musculus) PubMed

 14918.

LINKIN promotes adhesion between neighboring cells through its extracellular domain.[LINKIN] (Mus musculus) PubMed

 14919.

The crystal structure of OXA-163 determined at 1.72 A resolution reveals an expanded active site compared to that of OXA-48, which allows the bulky substrate ceftazidime to be accommodated. [OXA-163] (Mus musculus) PubMed

 14920.

These findings suggest that the activation of ERK1 occurs as a secondary response to chemoattractants and that other cell-cell signaling mechanisms contribute to this activation.[ERK1] (Mus musculus) PubMed

 14921.

Theinvertase from Enterobacter cloacae is a beta-fructofuranosidase at neutral pH range. [invertase] (Mus musculus) PubMed

 14922.

These results identify previously uncharacterized regions distributed throughout the protein sequence of ASPP2 as determinants of CagA binding, providing mechanistic insight into apoptosis reprogramming by CagA. [CagA] (Mus musculus) PubMed

 14923.

In this study, OmpG is extended by 38 amino acids to produce a 16-stranded beta-barrel. Additional 38 residues in the mutant formed unordered structure at acidic pH. [OmpG] (Mus musculus) PubMed

 14924.

these results suggest that ALT1 negatively functions in alkaline tolerance mainly through the defense against oxidative damage, and provide a potential two-step strategy for improving the tolerance of rice plants to alkaline stress. (Mus musculus) PubMed

 14925.

Resonance Raman Spectra of Five-Coordinate Heme-Nitrosyl Cytochromes c' show the effect of the proximal heme-NO environment. [Cytochrome c'] (Mus musculus) PubMed

 14926.

The expression of two interleukin-23alpha (p19) isoforms have been identified and described in rainbow trout Oncorhynchus mykiss and Atlantic salmon Salmo salar. [p19a], [p19b] (Mus musculus) PubMed

 14927.

The expression of two interleukin-23alpha (p19) isoforms have been identified and described in rainbow trout Oncorhynchus mykiss and Atlantic salmon Salmo salar. [p19a], [p19b] (Mus musculus) PubMed

 14928.

CgNR8A1 binds strongly to conserved DNA core motifs DR0, DR2, and DR4 and weakly to DR1, DR3, DR5, Half, and Pal0. [CgNR8A1] (Mus musculus) PubMed

 14929.

The full-length complementary DNA (cDNA) of the S. kowalevskii tra homolog (Sktra) has a 3786-bp open reading frame that encodes a 1261-amino acid sequence including a TRA-CAM domain and an arginine/serine (RS)-rich domain, both of which are characteristic of TRA orthologs. [TRA] (Mus musculus) PubMed

 14930.

Data suggest that compounds that inhibit quorum sensing operon, specifically agrA, can enhance host defense/innate immunity against S. aureus skin infections without bacterial drug resistance. [agrA, accessory gene regulator A] (Mus musculus) PubMed

 14931.

The results suggest that there are strong selective constraints against mutational changes in ryhB-1 gene sequence, leading to high levels of nucleotide conservation in ryhB-1 gene sequences among the genus of Salmonella.[ryhB-1] (Mus musculus) PubMed

 14932.

Peptidoglycan deacetylation by PgdA plays an important role in modulating host inflammatory responses to H. pylori, allowing the bacteria to persist and induce carcinogenic consequences in the gastric niche.[PgdA protein, Helicobacter pylori] (Mus musculus) PubMed

 14933.

this study identified the adenosine triphosphate (ATP) catalytic region [adenosine triphosphatase (ATPase)] in the amino-terminal half of the clock protein KaiC as the minimal pacemaker that controls the in vivo frequency of the cyanobacterial clock [KaiC] (Mus musculus) PubMed

 14934.

The 6S RNA (encoded by ssrS) contributes to the optimization of cellular adaptation and is an important factor involved in the regulation of growth and expression of key genes for the biosynthesis of actinorhodin.[ssrS] (Mus musculus) PubMed

 14935.

CELF1 showed RNA binding activity but CELF2 did not. [CELF1 and CELF2] (Mus musculus) PubMed

 14936.

Here the authors present clear evidence of the participation of CreA in carbon repression of penicillin biosynthesis and expression of the pcbAB gene, encoding the first enzyme of the pathway.[CreA] (Mus musculus) PubMed

 14937.

The Shigella tip complex (TC) is composed of IpaD, a hydrophilic protein, and IpaB, a hydrophobic protein, which later forms part of the injection pore in the host membrane. Here we used labelling and crosslinking methods to show that TCs from a DeltaipaB strain contain five IpaD subunits while the TCs from wild-type can also contain 1 IpaB and 4 IpaD subunits.[IpaD, IpaB] (Mus musculus) PubMed

 14938.

The structural features associated with Chi binding are described in greater detail and discussed in relation to the related E.coli RecBCD system, are described.[RecB, RecC, RecD] (Mus musculus) PubMed

 14939.

These results suggest that repression of wee1(+) expression is primarily owing to Mei4p-mediated transcriptional interference.[Wee1] (Mus musculus) PubMed

 14940.

Vibrio vulnificus RtxA1 modulated calcium flux contributes reduced internalization in phagocytes [rtxA1 RTX repeat-containing calcium-binding cytotoxin] (Mus musculus) PubMed

 14941.

VopE is localized to mitochondria during infection; it inhibits mitochondrial clustering and binds to the GTPase-I domain of Miro [VopE] (Mus musculus) PubMed

 14942.

study identified a cysteine protease, conserved among bacteria containing the L27 N-terminal extension, which performs post-translational cleavage of L27[cysteine protease, PRP; L27] (Mus musculus) PubMed

 14943.

Fatty acid initiates signaling through class I PI3 kinases that result in activation of EhTMKB1-9 expression.[EhTMKB1-9] (Mus musculus) PubMed

 14944.

Rho3 regulated polarized growth, conidiation, appressorium formation and virulence[Rho3] (Mus musculus) PubMed

 14945.

Results identified residues in LuxN governing ligand specificity and a series of LuxN variants with reduced kinase activity, harboring mutations in the region immediately adjacent to the AI-1-binding site. [LuxN] (Mus musculus) PubMed

 14946.

The Escherichia coli siderophore enterochelin is relatively inexpensive to produce and is partially privatized such that it can be efficiently shared only at high producer cell densities. (Mus musculus) PubMed

 14947.

type VI secretion membrane core complex is assembled by sequential addition of three type VI subunits--TssJ, TssM and TssL; structure of the fully assembled complex at 11.6 A resolution, determined by negative-stain electron microscopy [TssM, J & L] (Mus musculus) PubMed

 14948.

The ermB gene was not detected among the investigated strains [ermB gene] (Mus musculus) PubMed

 14949.

The use of GRA1 and GRA7 antigens as markers of Toxoplasma gondii infection in dogs, using a specific and sensivite ELISA, is reported.[GRA1; GRA7] (Mus musculus) PubMed

 14950.

Data on VIM31 3-dimensional structure suggest that the so-called 'flapping loop' (loop 1) and loop 3 of VIM31 are not positioned as in isoenzyme VIM2; in this respect, structure of VIM31 is closer to that of VIM4. [VIM31, metallo-beta-lactamase-31] (Mus musculus) PubMed

 14951.

Ecm33 contribute differentially to the conidiation and multi-stress tolerance.[Ecm33] (Mus musculus) PubMed

 14952.

Dsc E3 ligase is a Golgi-localized complex required for sterol regulatory element-binding protein (SREBP) transcription factor activation that shows architectural similarity to endoplasmic reticulum-associated degradation E3 ligases. [SREBP] (Mus musculus) PubMed

 14953.

PicC's major role in vivo may be to limit Citrobacter rodentium's stimulation of the host's innate immune system.[PicC] (Mus musculus) PubMed

 14954.

Pneumococcal surface proteins PavB and PspC bind human TSP-1 specifically. [PavB, PspC] (Mus musculus) PubMed

 14955.

The study provides a quantitative description of the catalytic mechanism utilized by DsbA that offers insight into the entire sequence of events that occurs in the periplasm from the unfolded-reduced state to the folded-oxidized protein. [DsbA] (Mus musculus) PubMed

 14956.

The finding that biomass formation of the Aspergillus niger niger DeltaveA strain was reduced twofold shows that VeA not only impacts spore dispersion capacity but also colonization capacity of Aspergillus niger.[VeA] (Mus musculus) PubMed

 14957.

Data indicate significant increases in the stability of SitA upon binding to divalent metal cations: [SitA] (Mus musculus) PubMed

 14958.

RhaR, is a regulator involved in L-rhamnose release and catabolism.[RhaR] (Mus musculus) PubMed

 14959.

The effect of foster hen rearing on the two genetic lines and their hypothalamic morphology, and the role of tyrosine hydroxylase and vasotocin levels in feather pecking, are reported. (Mus musculus) PubMed

 14960.

The structure of the TP0435 (Tp17) lipoprotein is characterized by an eight-stranded beta-barrel protein with a shallow "basin" at one end of the barrel and an alpha-helix stacked on the opposite end. [Tp17] (Mus musculus) PubMed

 14961.

Mutations in glucosyltransferases FKS1 and FKS2 are responsible for the growing resistance to echinocandins in the United States. [FKS1], [FKS2] (Mus musculus) PubMed

 14962.

CYP5122A1 isimplicated in the anti-leishmanial action of the Arylimidamides. [CYP5122A1] (Mus musculus) PubMed

 14963.

Endonuclease III uses a multistep mechanism of damage recognition, which likely involves Gln41 and Leu81 as lesion sensors. [Endonuclease III] (Mus musculus) PubMed

 14964.

Strain K904 with deletion of both prtS and slpB genes was defective in secreted protease activity and cytotoxicity to human cell lines.[SlpB] (Mus musculus) PubMed

 14965.

Thus, Sap6 (but not Sap5) has an alternative novel function in cell-cell aggregation, independent of its proteinase activity, to promote infection and virulence in oral candidiasis.[Sap6] (Mus musculus) PubMed

 14966.

Data (including data from studies in knockout mice) suggest that caspase-1/11 are involved in development of atherosclerosis; hematopoietic deletion of caspase-1/11 results in strong reduction in atherosclerotic plaque size. (Casp11, caspase-11) (Mus musculus) PubMed

 14967.

Combined CagA expression, p-SHP-2 expression, and p-ERK expression showed an increased positive predictive value (93.3% [14/15] vs. 81.8% [18/22]) and an increased specificity (95.5% [21/22] vs. 81.8% [18/22])[CagA] (Mus musculus) PubMed

 14968.

In this study, tet(M) detected in E. coli seems not to have been transferred from enterococci, although it can not be ruled out that the horizontal transfer of this gene occurred from other intestinal tract bacteria [tet(M)] (Mus musculus) PubMed

 14969.

Data suggest that alteration of enolase sequence by insertion of conserved sequence from other enolases affects affinity for magnesium ions, protein conformation, and stability of Plasmodium falciparum enzyme. [eno1, enolase] (Mus musculus) PubMed

 14970.

Authors demonstrate that both TrxA and TrxC are important in protecting Helicobacter pylori from oxidative stress.[TrxA, TrxC] (Mus musculus) PubMed

 14971.

These findings show that miR-139-3p and miR-199a-3p are involved in the defective hematopoietic function of interstrand crosslink-repair deficient myeloid progenitors[mir199] (Mus musculus) PubMed

 14972.

Chicken ASBT cDNA consisted of 91 bp of the 5'-untranslated region, 1,083 bp of the coding region, and 1,896 bp of the 3'-untranslated region. The cDNA encoded a protein of 360 amino acids with significant sequence identity to mammal and fish ASBT.[ASBT] (Mus musculus) PubMed

 14973.

Single-stranded DNA-binding protein (SSB) interacts with E. coli ribonuclease HI (RNase HI) to form a complex with heightened nuclease activity. [RNase HI, SSB] (Mus musculus) PubMed

 14974.

Collectively, the Schizosaccharomyces pombe Hos3 also participate in the cellular defense against oxidative, nitrosative and nutritional stresses through down-regulating reactive oxygen species and nitric oxide levels.[Hos3] (Mus musculus) PubMed

 14975.

Report lipolytic properties of Yarrowia lipolytica LIP8. (Mus musculus) PubMed

 14976.

The results of this work provide a basis for future cloning and application studies of maize RCI2 genes. (Mus musculus) PubMed

 14977.

These results indicate that the expression of the rice rgMT gene in transgenic yeast and Arabidopsis is implicated in improving their tolerance for certain salt and peroxide stressors (Mus musculus) PubMed

 14978.

The refolded methyltransferase of Dengue virus 3 displays methylation activity comparable to native enzyme, and its crystal structure at 2.1 A is almost identical to that of native methyltrasferase. [methyltransferase] (Mus musculus) PubMed

 14979.

Suggest alpha-syntrophin (SNTA) does not regulate ABCA1 activity and insulin release but may have a role in regulating glucose uptake, ERK and SR-BI levels, and sphingomyelin metabolism in obesity. (Mus musculus) PubMed

 14980.

miR26b may have a proapoptotic role in granulosa cells by regulating SMAD4 expression.[MiR26b, sus scrofa] (Mus musculus) PubMed

 14981.

Results found that the RstA regulator is required for avian pathogenic Escherichia coli virulence in the chicken infection model. [RstA] (Mus musculus) PubMed

 14982.

Snf1/AMPK-deficient cells remodel their metabolism fueling mitochondria and show glucose and amino acids addiction, a typical hallmark of cancer cells.[Snf1] (Mus musculus) PubMed

 14983.

Together, these data indicate that FluG of Aspergillus niger is a repressor of secretion.[FluG] (Mus musculus) PubMed

 14984.

An A>G SNP was found at position 235 of exon 2. 2 G>C SNPS at positions 259 and 260, and a T>G SNP at position 371 of exon 4 were found. Modifications in secondary structure were predicted. No SNPS in DHFR were seen. (DHPS and DHFR). (Mus musculus) PubMed

 14985.

ARBORKNOX1 homeodomain transcription factor regulates woody growth through binding to evolutionarily conserved target genes of diverse function.[ARBORKNOX1] (Mus musculus) PubMed

 14986.

low-pH crystal structure of Escherichia coli Threonine aldolase at 2.1 A resolution, with a non-covalently bound uncleaved l-serine substrate, and a PLP cofactor bound as an internal aldimine (L-Threonine aldolase). (Mus musculus) PubMed

 14987.

These data demonstrate that GelE from Enterococcus faecalis can regulate enteric epithelial permeability via PAR2.[GelE] (Mus musculus) PubMed

 14988.

The pathogenesis of experimental cerebral malaria was suppressed in C57BL/6 mice infected with Plasmodium berghei ANKA lacking the hmgb2 gene. (Mus musculus) PubMed

 14989.

HylB encodes a hyaluronate lyase while hylZ encodes a beta-N-acetylglucosaminidase. [HylB, HylZ] (Mus musculus) PubMed

 14990.

A synthetic abscisic acid (ABA)/stress-inducible promoter was designed to control the expression of a late embryogenesis abundant protein (HVA1) in transgenic rice.[HVA1] (Mus musculus) PubMed

 14991.

Glycosylation of Skp1 promotes formation of Skp1-cullin-1-F-box protein complexes in dictyostelium [Skp1] (Mus musculus) PubMed

 14992.

Loss of FabT affects membrane fatty acid composition [FabT] (Mus musculus) PubMed

 14993.

role of the QseC quorum-sensing sensor kinase in epinephrine-enhanced motility and biofilm formation by Escherichia coli [QseC] (Mus musculus) PubMed

 14994.

Our results reveal a crucial role for the miR-200 family in beta cell survival and the pathophysiology of diabetes (Mus musculus) PubMed

 14995.

These results suggest that OsHAP2E could contribute to conferring biotic and abiotic resistances and increasing photosynthesis and tiller numbers.[OsHAP2E] (Mus musculus) PubMed

 14996.

The dimerization process is an early event during bc1 complex biogenesis and that the presence of Rip1, differently from previous proposals, is not essential for this process.[Rip1] (Mus musculus) PubMed

 14997.

ZUO1 and JJJ1, which are conserved throughout eukaryotes, arose from an ancient duplication of a progenitor J-protein gene that encoded the zuotin homology domain ribosome-binding region.[JJJ1, Zuo1] (Mus musculus) PubMed

 14998.

The stress response of OsETHE1 is dependent on light and that darkness largely suppresses the stress response of this gene.[OsETHE1] (Mus musculus) PubMed

 14999.

The authors propose that Stl can be considered to be a cross-species dUTPase inhibitor. (Mus musculus) PubMed

 15000.

The N-terminal domain of the Epa1p adhesin from yeast Candida glabrata (N-Epa1p) is a calcium-dependent lectin, which confers the opportunistic yeast the ability to adhere to human epithelial cells. (Mus musculus) PubMed

 15001.

results indicate that karilysin modulates the host immune response through regulation of TNF-alpha secretion, and should therefore be considered as a new virulence factor of T. forsythia[karilysin] (Mus musculus) PubMed

 15002.

vCXCL-1 polymorphisms affect the binding affinity, receptor usage, and differential peripheral blood neutrophil activation that could contribute to viral dissemination and pathogenesis. [vCXCL-1] (Mus musculus) PubMed

 15003.

A molecular model of the monomeric p7 genotype 1a protein is optimized and assembled into a hexameric bundle for comparison with both the 5a hexamer structure and another hexameric bundle generated using the genotype 1b monomer structure.[p7 protein] (Mus musculus) PubMed

 15004.

ClpXP protease of methicillin-resistant Staphylococcus aureus USA300 has an important role in controlling cell wall metabolism and determining strain-dependent beta-lactam resistance. [ClpX], [ClpP] (Mus musculus) PubMed

 15005.

UPC2A is required for high-level azole antifungal resistance in Candida glabrata. [UPC2A] (Mus musculus) PubMed

 15006.

this study proposed an Mck2-mediated mechanism by which MCMV exploits alveolar macrophages to increase replication upon first encounter with the host's lung mucosa [Mck2]. (Mus musculus) PubMed

 15007.

Data suggest that initial step of dioxygen activation by tryptophan dioxygenase is direct electrophilic addition of heme-bound oxygen to indole ring of L-tryptophan. [TDO, tryptophan dioxygenase] (Mus musculus) PubMed

 15008.

TNF binding protein of variola virus, CrmB, acts as a TNF antagonist at epicutaneous application [CrmB] (Mus musculus) PubMed

 15009.

Tg-ncRNA-1 is involved in the early steps of bradyzoite differentiation.[Tg-ncRNA-1] (Mus musculus) PubMed

 15010.

Report negative and positive temperature dependence of potassium leak in MscS mutants, suggesting this protein has roles in mechanosensation and thermosensation. (Mus musculus) PubMed

 15011.

The metacaspase (Mca1p) has a dual role in farnesol-induced apoptosis in Candida albicans (Mus musculus) PubMed

 15012.

The crystal structure of the C. albicans Wor1 WOPR segments in complex with a double-stranded DNA corresponding to one promoter region of WOR1, is reported.[Wor1] (Mus musculus) PubMed

 15013.

These findings suggest that cognate UL112-113 proteins derived from calpain-catalysed proteolysis are involved in the human cytomegalovirus replication process.[UL113] (Mus musculus) PubMed

 15014.

Mir-660 inhibits lung tumorigenesis by targeting MDM2-p53 interaction. [MIR660] (Mus musculus) PubMed

 15015.

The sakA gene was involved not only in tolerance against oxidative and heat stresses, but also played a role in asexual development, chitin deposition, yeast cell generation in vitro and survival inside mouse and human macrophages.[sakA] (Mus musculus) PubMed

 15016.

Here, the authors demonstrate that Ndt80p plays a role in l-sorbose utilization through regulating SOU1 in Candida albicans.[Ndt80p, SOU1] (Mus musculus) PubMed

 15017.

Taken together, these results demonstrated that Hsf is not a straight molecule but is folded and doubled over.[Hsf] (Mus musculus) PubMed

 15018.

FgSte12 is a downstream target of FgSte11-Ste7-Gpmk1 and plays an important role in pathogenicity in F. graminearum.[FgSte12] (Mus musculus) PubMed

 15019.

Endoplasmic reticulum stress is critical for regulation of dendritic cell apoptotic process in response to Helicobacter pylori VacA protein stimulation. (Mus musculus) PubMed

 15020.

PsMPK7 gene in P. sojae is important not only for responses to various stresses, but also for reactive oxygen species detoxification, cyst germination, sexual oospore production and infection of soybean.[PsMPK7] (Mus musculus) PubMed

 15021.

Kpna7 may function in early embryonic development as a unique nuclear transporter for egg-specific proteins. [Kpna7] (Mus musculus) PubMed

 15022.

Ftr1 and Ftr2 are important for growth under iron-limited condition. [Ftr1 and Ftr2] (Mus musculus) PubMed

 15023.

HuR plays a significant role in centrosome amplification and genomic instability [mmu-miR-142] (Mus musculus) PubMed

 15024.

Data suggest that in ccNiR the strong-field heme ligand cyanide causes large positive shift in the active site's midpoint potential; nitrite, the physiological substrate, is also a likely strong-field ligand. [ccNiR, cytochrome c nitrite reductase] (Mus musculus) PubMed

 15025.

Overexpression of pectinase family genes may be the direct cause of rice floral organ abortion at high temperatures. [pectinase] (Mus musculus) PubMed

 15026.

PpKAC1 and PpKAC2 are required for chloroplast dispersion under uniform white light conditions, and the two proteins are functionally equivalent.[PpKAC1, PpKAC2] (Mus musculus) PubMed

 15027.

Thus, these data provide evidence for a significant role for AtlL in adherence and internalization processes as well as in biofilm formation of Staphylococcus lugdunensis.[AtlL] (Mus musculus) PubMed

 15028.

These results indicate that the activation of TA system toxins can suppress the sigma(E) essentiality and affect the extracytoplasmic stress responses.[sigma(E)] (Mus musculus) PubMed

 15029.

This study showed that YqjA is critical for E. coli to survive at pH 8.5 to 9.5; YqjA requires sodium and potassium for this function.[YgjA] (Mus musculus) PubMed

 15030.

The authors report a stable polymorphism in the bony armor of threespine stickleback maintained with a deficit of heterozygotes at the major underlying gene, Ectodysplasin (Eda). The deficit vanishes at the embryo life stage and re-emerges in adults.[eda] (Mus musculus) PubMed

 15031.

PLP1 is distributed in micronemes in a manner similar to its distribution in tachyzoites. [PLP1] (Mus musculus) PubMed

 15032.

We demonstrate here for the first time that the mitochondrial enzyme DLST plays an essential role in the modulation of the heart rate in zebrafish (Mus musculus) PubMed

 15033.

Efficient production of chloramphenicol from the free arylamine precursor suggests that CmlI catalyzes the ultimate step in the biosynthetic pathway and that the precursor is not bound to the nonribosomal peptide synthetase during this step. [CmlI] (Mus musculus) PubMed

 15034.

Metformin promotes irisin release from murine skeletal muscle into blood, independently of AMPK pathway activation. (Mus musculus) PubMed

 15035.

The study reveals that (15) N labeling was different in total organic matter, total soluble protein and the Rubisco fraction.[Rubisco] (Mus musculus) PubMed

 15036.

The results indicate that MaASR acts as a crucial regulator of photosynthesis, respiration, carbohydrate and phytohormone metabolism, and signal transduction to mediate drought stress tolerance (MaASR). (Mus musculus) PubMed

 15037.

cloning of alkaline serine protease gene from G. stearothermophilus and its expression in mesophilic E. coli strain BL21 (DE3) is reported; purification and characterization of the expressed protease is also described [alkaline protease] (Mus musculus) PubMed

 15038.

An extracellular metalloprotease of V. vulnificus, VvpM induces apoptosis of human cells via a pathway consisting of ERK activation, cytochrome c release, and then activation of caspases-9 and -3. [VvpM] (Mus musculus) PubMed

 15039.

finding presents that lipoteichoic acid synthase (LtaS) is another target of RNAIII and RNAIII suppresses the expression of LtaS via acting as an antisense RNA in S. aureus [LtaS] (Mus musculus) PubMed

 15040.

report describes functional characterization of a cadmium resistance operon found in the non-MRSA S. aureus ATCC12600 and demonstrates that the cadC gene product from S. aureus ATCC12600 has a positive role in cadmium efflux [cadC] (Mus musculus) PubMed

 15041.

Interleukin-37 inhibits the activation of mouse dendritic cells via suppressing production of co-stimulatory molecules CD80 and CD86. {IL-37] (Mus musculus) PubMed

 15042.

subpicosecond protein motion is dynamically coupled to hydride transfer catalyzed by hsDHFR but not ecDHFR [DHFR] (Mus musculus) PubMed

 15043.

These findings suggest that signal transmission in Tsr involves modulation of control cable helicity through interaction of the I214 side chain with the cytoplasmic membrane.[Tsr] (Mus musculus) PubMed

 15044.

PpJAZ1 may alter jasmonic acid signaling in different plant organs, resulting in autogamy as a reproductive assurance mechanism.[PpJAZ1] (Mus musculus) PubMed

 15045.

Amino acid residues 24-111, 144-176, 203-251, 319-361, 371-401, 451-476, and 492-546 of NS1 are identified as B-cell epitopes. [NS1] (Mus musculus) PubMed

 15046.

Data suggest that Bradi1g15030 brassinosteroid C-6 oxidase homolog BdBRD1 is a late-flowering gene: [BRD1] (Mus musculus) PubMed

 15047.

The rttA gene plays important roles in morphogenesis, carbohydrate metabolism, stress response, and pathogenesis in Penicillium marneffei.[rttA] (Mus musculus) PubMed

 15048.

gdpS functioned through direct RNA-RNA base pairing with the 5' untranslated region (5'UTR) of sarS mRNA and that a putative 18-nucleotide region played a significant role in the regulatory process. [gdpS, sarS] (Mus musculus) PubMed

 15049.

Linkage of HAT3-mediated PCNA acetylation to PCNA monoubiquitination following UV exposure (HAT3 and PCNA). (Mus musculus) PubMed

 15050.

Phosphatidylcholine-specific phospholipase C (PC-PLC) signaling pathway may increase calcium entry and promote vasoconstriction in murine resistance arteries. (Mus musculus) PubMed

 15051.

ENL1 encodes an SNF2 helicase family protein that is essential for the extremely rapid nuclear cycle during syncytial endosperm development in rice. [ENL1] (Mus musculus) PubMed

 15052.

structural analysis indicated CT009 shares high level of structural similarity to RodZ, revealing the conserved orientation of 2 residues critical for MreB interaction; cellular localization analysis of CT009 showed uniform membrane staining [CT009] (Mus musculus) PubMed

 15053.

By blocking cell death, NleB promotes enterocyte survival and thereby prolongs enteropathogenic Escherichia coli attachment to the gut epithelium.[NleB] (Mus musculus) PubMed

 15054.

Amino acid composition and transcription start sites for PSHCP gene in Synechococcus sp. WH 8102 [PSHCP] (Mus musculus) PubMed

 15055.

BmSPI39 is a TIL-type protease inhibitor potently inhibited the virulence protease CDEP-1 of Beauveria bassiana (Mus musculus) PubMed

 15056.

Hsp100 proteins play a role in survival and virulence of pathogens. [HSP100] (Mus musculus) PubMed

 15057.

demonstration of mechanism of PglK-catalysed lipid-linked oligosaccharide flipping based on crystal structures in distinct states, a newly devised in vitro flipping assay, and in vivo studies [PglK] (Mus musculus) PubMed

 15058.

these results reveal a novel function of miR-181 in embryo implantation through the regulation of LIF, and also indicate a potential link between miR-181 dysregulation and human embryo implantation defects. (Mus musculus) PubMed

 15059.

Results show that, unlike other membrane-bound CYPs that have high flexibility in the active site and a large range of ligands, the CYP51 active site is relatively rigid in simulations of both soluble and membrane-bound forms. [CYP51] (Mus musculus) PubMed

 15060.

The Ras gene was investigated for its role in exploratory behavior in C. elegans.[Ras protein] (Mus musculus) PubMed

 15061.

Data show that nuclear factor Y (NF-Y) transcription factor TaNFYA10-1 (KM983028) is involved in the regulation of growth under salinity stress conditions: [NF-YA10-1] (Mus musculus) PubMed

 15062.

Gal27B has a higher temperature optimum at 75 degrees C and Gal27A shows stability over the broadest pH range. [Gal27A, Gal27B] (Mus musculus) PubMed

 15063.

Eps1p protein disulfide isomerase conserves classic thioredoxin superfamily amino acid motifs but not their functional geometries [Eps1] (Mus musculus) PubMed

 15064.

This study suggest that RNase J is a zinc-dependent nuclease using two-metal-ion catalysis (RNase J). (Mus musculus) PubMed

 15065.

The results suggest that D14L and D14 confer their effects via an strigolactones (SL) independent pathway and an SL signaling pathway respectively. (Mus musculus) PubMed

 15066.

The data supports a model in which arginine methylation acts as a switch that changes the function of DRBD18 from an mRNA destabilizing to an mRNA stabilizing protein (DRBD18). (Mus musculus) PubMed

 15067.

molecular dynamics simulations of E. coli glutaredoxin1 [glutaredoxin 1] (Mus musculus) PubMed

 15068.

The data suggest that colicin A forms dimers upon membrane insertion. [colicin A] (Mus musculus) PubMed

 15069.

our results suggest that PNGase Yl, the first biochemically characterized yeast PNGase A homologue, can be developed through protein engineering as a useful deglycosylation tool for N-glycosylation study. (Mus musculus) PubMed

 15070.

crystal structure of Vibrio cholerae TssL (VcTssL), a core component of the type VI secretion system [TssL] (Mus musculus) PubMed

 15071.

This study developed a model for target dna (tDNA) binding by MLV integrase that implicates the alpha2 helix of the catalytic core domain and the beta1-beta2 loop of the C-terminal domain to be important determinants of tDNA binding. (Mus musculus) PubMed

 15072.

Mammalian eIF2alpha kinases evolved to maximize their interactions with the evolutionarily conserved Ser51 residue of eIF2alpha in response to diverse stress conditions.[eIF2alpha] (Mus musculus) PubMed

 15073.

Saccharomyces cerevisiae linker histone physically interacts with Arp4p.[Arp4p] (Mus musculus) PubMed

 15074.

Our results highlight the importance of feedback regulation in building epigenetic memory and uncover Hsp104 and Dicer as homeostatic controllers (Mus musculus) PubMed

 15075.

identified Nfu as an Fe-S cluster carrier, which aids in the maturation of Fe-S proteins; conclude that Nfu is necessary for staphylococcal pathogenesis and establish Fe-S cluster metabolism as an attractive antimicrobial target [Nfu] (Mus musculus) PubMed

 15076.

The role of interleukin-6 (IL-6), and ET signaling in advanced pulmonary arterial hypertension progression, was examined.[Vegfr] (Mus musculus) PubMed

 15077.

A crystal structure of Staphylococcus aureus PpaC in complex with catalytic Mn(2+). [PpaC] (Mus musculus) PubMed

 15078.

[FRIZZY PANICLE (FZP)] - drives supernumerary inflorescence spikelets (Mus musculus) PubMed

 15079.

DNA-modified electrochemistry shows that the 4Fe-4S cluster of DNA-bound DinG, an ATP-dependent helicase that repairs R-loops, is redox-active at cellular potentials and ATP hydrolysis increases DNA-mediated redox signaling. [DinG] (Mus musculus) PubMed

 15080.

Dynamics of the intrinsically disordered C-terminal domain of the nipah virus nucleoprotein and interaction with the x domain of the phosphoprotein is unveiled by NMR spectroscopy.[nucleoprotein] (Mus musculus) PubMed

 15081.

the cryptococcal CRZ1/SP1-like gene plays an important role not only in cell wall integrity, but also in delay of cell cycle progression, survival under limited aeration, and in biofilm formation in the pathogenic yeast C. neoformans.[CRZ1] (Mus musculus) PubMed

 15082.

X-ray crystallographic structure of G. stearothermophilus alpha-amylase. [amyS] (Mus musculus) PubMed

 15083.

Kin13Ap is required for divisions of micronuclei and macronuclei. Kin13Bp and Kin13Cp, act synergistically to support cell multiplication and ciliary functions. (Kin13Ap, Kin13Bp and Kin13Cp) (Mus musculus) PubMed

 15084.

study reports that RpfB is an authentic fatty acyl-CoA ligase that plays a role in fatty acid beta-oxidation; however, it plays a more important role in pathogenesis by counteracting the thioesterase activity of RpfF[RpfB] (Mus musculus) PubMed

 15085.

characterization of sirohaem decarboxylase (AhbA/AhbB) is reported in molecular detail; kinetic parameters of the s enzyme have been determined, the enzyme crystallized and its structure has been elucidated [sirohaem decarboxylase] (Mus musculus) PubMed

 15086.

PTL-1 functions via neurons to modulate SKN-1, clarifying the role of this protein in the stress response and longevity.[PTL-1] (Mus musculus) PubMed

 15087.

The strong binding force, slow dissociation and clustering of SdrG provide a molecular foundation for the ability of S. epidermidis to colonize implanted biomaterials and to withstand physiological shear forces [SdrG] (Mus musculus) PubMed

 15088.

PIN1 is a bona fide prolyl isomerase and that it interacts with the host ubiquitin ligase FBW7, leading to its degradation and subsequent stabilization of c-JUN, which promotes transformation [PIN1] (Mus musculus) PubMed

 15089.

PIN1 is a bona fide prolyl isomerase and that it interacts with the host ubiquitin ligase FBW7, leading to its degradation and subsequent stabilization of c-JUN, which promotes transformation [PIN1] (Mus musculus) PubMed

 15090.

The PH gene determines fruit acidity. (Mus musculus) PubMed

 15091.

The data suggest that the PLAIIIdelta gene plays an important role in cell morphology and organ size through its involvement in the regulation of auxin distribution in Arabidopsis and Brassica napus.[pPLAIIIdelta] (Mus musculus) PubMed

 15092.

Data indicate that the tryptophan W243 residue was critical to the substrate and product specificity of Os9BGlu31 transglucosidase: [Os9BGlu31] (Mus musculus) PubMed

 15093.

The FimD C-terminal domains provide the high-affinity substrate-binding site but that these domains are masked in the resting usher. Domain masking requires the FimD plug domain, which serves as a switch controlling usher activation. [FimD] (Mus musculus) PubMed

 15094.

FscN is a siderophore-interacting protein.[FscN] (Mus musculus) PubMed

 15095.

Rice BGlu1(Os3BGlu7)is a glycoside hydrolase family 1 beta-glucosidase that hydrolyzes cellooligosaccharides with increasing efficiency as the degree of polymerization (DP) increases from 2 to 6, indicating six subsites for glucosyl residue binding.(BGlu1) (Mus musculus) PubMed

 15096.

OsC3H47 is a newly discovered gene that can control rice drought-stress response, and it may play an important role in abscisic acid feedback and post-transcription processes. [OsC3H47] (Mus musculus) PubMed

 15097.

The study reports the crystal structure of the fission yeast Atg101-Atg13 complex. [Atg101] (Mus musculus) PubMed

 15098.

The pentameric gH/gL/pUL128-131 complex, but not gH/gL, blocks viral entry to epithelial cell. [gL, UL128] (Mus musculus) PubMed

 15099.

PAM activated Plasminogen Glycoform II. [PAM] (Mus musculus) PubMed

 15100.

The structure of the radical S-adenosyl-L-methionine [FeFe]-hydrogenase maturase HydG is characterized by two internal tunnels connecting its tyrosine-binding pocket with the external medium and the C-terminal Fe4 S4 cluster-containing region.[HydG] (Mus musculus) PubMed

 15101.

the mof gene is essential for larval/pupal development and female fertility in T. castaneum (Mus musculus) PubMed

 15102.

The effects of a 10.5 M solution of aqueous urea on Helicobacter pylori urease were investigated over the course of a 500 ns molecular dynamics simulation. [urease] (Mus musculus) PubMed

 15103.

This study created models for the metal transfer complex of the N-Terminal region of CusB and CusF that share coordination of Cu(I) and thereby represent structural models for the metal transfer process. [CusB, CusF] (Mus musculus) PubMed

 15104.

The study investigates an unusual peroxide-dependent, heme-transforming reaction catalyzed by HemQ. [HemQ] (Mus musculus) PubMed

 15105.

analyze the structural basis for rejection of C:oxoG by MutY, using a synthetic crystallography approach to capture the enzyme in the process of inspecting the C:oxoG anti-substrate, with which it ordinarily binds only fleetingly (MutY DNA glycosylase) (Mus musculus) PubMed

 15106.

The spatiotemporal expression of MUC2, IgA, and pIgR in broiler chickens and Pekin ducks from the embryonic stage up to 21 day posthatch are reported.[IgA] (Mus musculus) PubMed

 15107.

NS3 protease is an intrinsically (partially) disordered protein with a complex conformational landscape due to its inherent plasticity and to the interaction with its different effectors. (Mus musculus) PubMed

 15108.

m2mAChR sensitive BK currents were activated in vestibular hair cells (VHCs) isolated by collagenase IA, while alpha9nAChR sensitive SK2 currents were activated in VHCs II isolated by trypsin.[m2mACHR, alpha9nACHR] (Mus musculus) PubMed

 15109.

Presented is the 2.65-A crystal structure of alanyl aminopeptidase N. [alanyl aminopeptidase N] (Mus musculus) PubMed

 15110.

a novel role for EhROM1 in amebic motility [ROM1]. (Mus musculus) PubMed

 15111.

CgNimC, with significant binding capability to lipopolysaccharies and gram-negative bacteria, was a novel phagocytic receptor involved in immune response of Pacific oyster.[NimC] (Mus musculus) PubMed

 15112.

A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction [NM23-H1] (Mus musculus) PubMed

 15113.

Serratia marcescens chitinase B catalyzes the hydrolysis of beta-1,4-glycosidic bond via an unusual substrate-assisted mechanism in which the substrate itself acts as an intramolecular nucleophile. [ChiB] (Mus musculus) PubMed

 15114.

This study characterized the interstrand DNA-DNA cross-links derived from abasic sites using bacteriophage phi29 DNA Polymerase [DNA Polymerase] (Mus musculus) PubMed

 15115.

This study reports a surprising property of NS3 protein: directionally biased melting of double-strand DNA in the absence of ATP. [NS3 protein] (Mus musculus) PubMed

 15116.

These findings underscore the essentiality of VPS15 and VPS34 signalling in modulation of host immune response, intracellular survival and virulence in C. glabrata.[VPS15 and VPS34] (Mus musculus) PubMed

 15117.

Cyclic di-AMP selectively binds to the KtrA RCK_C domain and signals the inactivation of potassium transport. [KtrA] (Mus musculus) PubMed

 15118.

hhoB, Synechocystis sp. PCC 6803 [New Entry] - Data suggest that photosystem II manganese-stabilizing protein (PsbO) is a natural substrate for the serine endopeptidase hhoB of Synechocystis sp. PCC 6803. [hhoB] (Mus musculus) PubMed

 15119.

miR-US25-1-5p inhibits viral replication by downregulating host cell targets. [miR-US25-1-5p] (Mus musculus) PubMed

 15120.

FLV2 and FLV4 mediate oxygen-dependent alternative electron flow in Synechocystis sp. PCC 6803 when electron acceptors such as carbon dioxide are not available.[FLV2, FLV4] (Mus musculus) PubMed

 15121.

OsJAZ9 acts as a transcriptional regulator by forming a transcriptional regulation complex with OsNINJA and OsbHLH to fine tune the expression of JA-responsive genes involved in salt stress tolerance in rice. [OsJAZ9] (Mus musculus) PubMed

 15122.

This study evaluated the role of IGF1 and phosphoinositol 3 kinase (PI3K) signaling in the pathogenesis of adrenocortical tumors in dogs and to identify pathway components that may hold promise as future therapeutic targets or as prognostic markers.[PI3K] (Mus musculus) PubMed

 15123.

Differential acetylation of histone H3 at the regulatory region of DREB1b promoter facilitates chromatin remodelling and transcription activation during cold stress. [DREB1b], [histone H3] (Mus musculus) PubMed

 15124.

These results revealed that the association of JadR3 and the gamma-butyrolactone SVB1 plays an important role in controlling a regulatory mini-network governing jadomycin biosynthesis.[JadR3] (Mus musculus) PubMed

 15125.

CstB may have evolved to facilitate the clearance of persulfides that occur upon elevation of the level of cellular hydrogen sulfide. [CestB] (Mus musculus) PubMed

 15126.

Surprisingly, SLO requires the coexpression and membrane localization of SPN to achieve cholesterol-insensitive membrane binding; in the absence of SPN, SLO's binding is characteristically cholesterol-dependent.[SLO, SPN] (Mus musculus) PubMed

 15127.

Together these data indicate that PopA adopted a novel role as topology specificity factor to help recruit components of the CtrA degradation pathway to the protease specific old cell pole of Caulobacter crescentus.[PopA] (Mus musculus) PubMed

 15128.

These results suggest there is a genetic interaction between the Aspergillus fumigatus calcineurin-CrzA and HOG pathway that is essential for full virulence.[CrzA] (Mus musculus) PubMed

 15129.

Data suggest TRH (TDH-related hemolysin) has lesser role than TDH in V. parahaemolyticus pathogenicity; both TRH and TDH appear to contribute to pathogenicity of V. parahaemolyticus found in shellfish in Japan. [TDH; thermostable direct hemolysin] (Mus musculus) PubMed

 15130.

The photoprotective role of CP29 phosphorylation in reducing singlet oxygen production and enhancing excess energy dissipation, was elucidated.[CP29, STN7] (Mus musculus) PubMed

 15131.

Taken together, the regulator ReiD is a trigger to accelerate the switch from more easily accessible nutrients to myo-inositol utilization by Salmonella typhimurium.[ReiD] (Mus musculus) PubMed

 15132.

The inhibitory effect of Cecropin P1 occurred during viral attachment, but not at viral entry into Marc-145 cells.[Cecropin P1] (Mus musculus) PubMed

 15133.

TaNFYA-B1 plays essential roles in root development and in nitrogen and phosphorus usage in wheat.[TaNFYA-B1] (Mus musculus) PubMed

 15134.

NKD controls a gene regulatory network involved in aleurone cell fate specification and cell differentiation.[NKD1, NKD2] (Mus musculus) PubMed

 15135.

Overexpression of RelA/SpoT homologs, RSH2a and RSH2b, induces the growth suppression of the moss Physcomitrella patens.[RSH2a], [RSH2b] (Mus musculus) PubMed

 15136.

TbPRMT1, TbPRMT3 TbPRMT6, and TbPRMT7 are functional interplay. [ TbPRMT1, TbPRMT3 TbPRMT6, and TbPRMT7] (Mus musculus) PubMed

 15137.

It is proposed that degradation of the Fur repressor mediated by the FtsH1/FtsH3 heterocomplex is critical for acclimation to iron depletion.[Fur, FtsH1, FtsH3] (Mus musculus) PubMed

 15138.

The predicted gene Y47G6A.17 encodes the key ciliopathy protein CEP290 in C. elegans. [CCEP-290] (Mus musculus) PubMed

 15139.

results clearly demonstrate that Awa1p present on the surface of sake yeast strain K7 inhibits adhesion between yeast cells and L. plantarum ML11-11, consequently impeding mixed-species biofilm formation [awa1] (Mus musculus) PubMed

 15140.

The structural characterization of a dearomatizing benzoyl-coA reductase containing an unprecedented tungsten cofactor is given. [Benzoyl-coA reductase] (Mus musculus) PubMed

 15141.

Results suggest that Lsm and YjeF domains of Edc3 are critical in hyphal growth and oxidative stress response [Edc3] (Mus musculus) PubMed

 15142.

CagA and VacA are critical factors for inducing gastric cancer and the subsequent progression of intestinal metaplasia from chronic gastritis with an increasing age.[vaca] [Caga] (Mus musculus) PubMed

 15143.

The data demonstrate that the attenuated phenotype of Burkholderia cenocepacia DeltapaaABCDE is due to quorum sensing inhibition by release of phenylacetic acid, affecting N-octanoyl-L-homoserine lactone signalling.[paaABCDE] (Mus musculus) PubMed

 15144.

CaHSP70a interacts with the type III effector AvrBsT and is required for cell death and immunity in plants.[AvrBsT] (Mus musculus) PubMed

 15145.

Prion protein C and copper support NMDAR S-nitrosylation and cooperatively exert neuroprotection. [Prion protein C, mice] (Mus musculus) PubMed

 15146.

Mini1 plays an important role in maintaining shoot apical meristem activity and promoting shoot development in rice.[Mini1] (Mus musculus) PubMed

 15147.

These findings suggest that the BabA may form different adhesive attachments to the gastric mucosa in ways that enhance the efficiency and stability of bacterial adhesion. (Mus musculus) PubMed

 15148.

Results show that CKI and CK2alpha phosphorylate different regions of PRR37. [CKI, CK2alpha, PPR37] (Mus musculus) PubMed

 15149.

cells infected with D26 virus were resistant to CTL killing. These results indicate that efficient viral persistence and spread require the combined functions of p12 and p8. (Mus musculus) PubMed

 15150.

Uptake of shikimate was mainly mediated by the shikimate transporter encoded by cgR_2523(shiA).[shiA] (Mus musculus) PubMed

 15151.

These results confirmed the direct regulation of ergosterol biosynthesis and iron uptake by SrbA in hypoxia and revealed new roles for SrbA in nitrate assimilation and heme biosynthesis. (Mus musculus) PubMed

 15152.

The Deltalac1 mutants showed reduced virulence on maize seedlings and fewer, less-pigmented teliospores in adult plants. The Deltapks1 mutant was unaffected in seedling virulence but adult plant tumors generated hyaline, nonmelanized teliospores. [Pks1; Lac1] (Mus musculus) PubMed

 15153.

The study investigated the apo (Fe(3+) free) form of periplasmic ferric binding protein (FbpA) under different conditions and monitored the changes in the binding and release dynamics of H2PO4(-). [FbpA] (Mus musculus) PubMed

 15154.

Protein-Protein Interactions in the Cyanobacterial Circadian Clock: Structure of KaiA Dimer in Complex with C-Terminal KaiC Peptides (Mus musculus) PubMed

 15155.

Polyamines increase the level of RpoS, the sigma38-RNA-polymerase subunit, even in non-amber-strain, to induce glutamate-dependent-acid resistance (GDAR) in Escherichia coli via gadE. [RpoS, gadE] (Mus musculus) PubMed

 15156.

ComCDE modulates the production of eDNA and biofilms.[comC, comD, comE] (Mus musculus) PubMed

 15157.

The results of this study revealed a relationship between CrCO gene and lipid metabolism in Chlamydomonas.[Constans] (Mus musculus) PubMed

 15158.

The 2.3-A structure of a fully folded SpA domain in complex with Fc, is reported.[SpA] (Mus musculus) PubMed

 15159.

Data suggest cytosolic Hog1 (excluded from nucleus) provides osmostress/ER stress protection; plasma membrane-anchored Hog1 still up-regulates GPD1 (glycerol phosphate dehydrogenase 1) expression; nuclear Hog1 is required for glycerol accumulation. (Mus musculus) PubMed

 15160.

Programmed death-1 (PD-1), programmed death-ligand 1 (PD-L1), and EBV-encoded RNA (EBER) expression in Hodgkin lymphoma. (Mus musculus) PubMed

 15161.

the specificity of LacY for sugar is determined solely by side-chain interactions with the galactopyranosyl ring, whereas affinity is increased by nonspecific hydrophobic interactions with the anomeric substituent.[LacY] (Mus musculus) PubMed

 15162.

An NMR-determined solution-state structure of the murine CMV homolog of UL50 (M50; residues 1-168) with a strikingly intricate protein fold that is matched by no other known protein folds in its entirety, is reported.[UL50] (Mus musculus) PubMed

 15163.

A novel protein, Callipygian (CynA), which localizes to the lagging edge before other proteins and becomes more tightly restricted as cells polarize, is reported. {Callipygian] (Mus musculus) PubMed

 15164.

Ust1 activity was able to partially reverse stuA- conidiophore defects in Aspergillus nidulans; ii) in U. maydis, normal development and virulence were strongly dependent on precise induction or repression of Ust1 activity. (Mus musculus) PubMed

 15165.

both polarity and fork-arrest efficiency are determined by a competition between rates of Tus displacement and rearrangement of Tus-Ter interactions that leads to blockage of slower moving replisomes by two distinct mechanisms [Tus] (Mus musculus) PubMed

 15166.

Association of Bombyx mori TRN-1 with Bombyx mori nucleopolyhedrovirus BRO-B/E is responsible for the inhibitory regulation of certain mRNAs at the post-transcriptional level.[TRN-1] (Mus musculus) PubMed

 15167.

OsHK3 play an important role in the regulation of abscissic acid-induced antioxidant defense.[OsHK3] (Mus musculus) PubMed

 15168.

a new NleE substrate, ZRANB3, that functions in PCNA binding and remodeling of stalled replication forks at the DNA damage sites. (Mus musculus) PubMed

 15169.

The study explores the complex mechanism of SSB protein binding to single-stranded DNA probed using solid-state nanopore sensors. [SSB protein] (Mus musculus) PubMed

 15170.

Interaction of nucleocapsid protein with host vimentin is required for virus infection. [N] (Mus musculus) PubMed

 15171.

These results suggest that equine infectious anemia virus Rev binding to the Rev-responsive element in viral RNA requires dimerization via a coiled-coil motif to juxtapose two RNA binding motifs, ARM-1 and ARM-2. (Mus musculus) PubMed

 15172.

This study reports the crystal structure of Thermobifida fusca Cse1 at 3.3 A degrees resolution. [Cse1] (Mus musculus) PubMed

 15173.

SnTox6 is a small secreted protein that induces necrosis on wheat lines harboring Snn6. Sensitivity to SnTox6, conferred by Snn6, was light-dependent and was shown to underlie a major disease susceptibility quantitative trait locus (QTL). [Snn6) (Mus musculus) PubMed

 15174.

introgression of Pi64 into susceptible cultivars via gene transformation and marker-assisted selection conferred high-level and broad-spectrum leaf and neck blast resistance to indica-sourced isolates. [Pi64] (Mus musculus) PubMed

 15175.

SnTox6 is a small secreted protein that induces necrosis on wheat lines harboring Snn6. Sensitivity to SnTox6, conferred by Snn6, was light-dependent and was shown to underlie a major disease susceptibility quantitative trait locus (QTL). [SnTox6) (Mus musculus) PubMed

 15176.

ARP3 protein and actin were spatially associated with maturing symbiosomes. Partial ARP3 silencing causes defects in symbiosome development. [ARP3] (Mus musculus) PubMed

 15177.

The Escherichia coli Hsp70, DnaK, was used as a model for Hsp70 proteins, focusing on its SBD domain, examining the changes in the lid conformation.[DnaK] (Mus musculus) PubMed

 15178.

DEC controls the phyllotactic pattern by affecting cytokinin signaling in rice. [DEC] (Mus musculus) PubMed

 15179.

iron transport was regulated by DtxR; Tfu_0249 was found to be working as DtxR; TWAGGTWAGSCTWACCTWA was found to be recognized and bound by Tfu_0249 to control iron transport [Tfu_0249] (Mus musculus) PubMed

 15180.

BcVEL1 but not its truncated versions interacts with BcLAE1 and BcVEL2. Deletions of BcVEL1 and BcLAE1 result in lost the ability to produce oxalic acid (OA), to colonize the host tissue, and to form sclerotia. [BcVEL1; BcLAE1] (Mus musculus) PubMed

 15181.

The interaction of different CagA variants with the kinase Src, was investigated.[CagA] (Mus musculus) PubMed

 15182.

homotetramerization of apo-SiRHP serves as a quality control mechanism to prevent formation of inactive holoenzyme in the case of limiting cellular siroheme. [SiRHP] (Mus musculus) PubMed

 15183.

Carboxyl-peptide plane stacking is important for stabilization of buried E305 of Trichoderma reesei Cel5A. [Cel5a] (Mus musculus) PubMed

 15184.

CSA1 plays a role in nucleotide excision repair. (Mus musculus) PubMed

 15185.

Report that the binding of one L-arg to E. coli arginine repressor apoprotein (ArgG) results in a holoprotein-like conformational distribution. (Mus musculus) PubMed

 15186.

Study identified the accessory protein, UNC93B1, from Atlantic salmon (Salmo salar) whole-genome shotgun contigs aided by the conserved gene synteny of genes flanking UNC93B1 in fish, birds and mammals. Phylogenetic analysis showed that salmon UNC93B1 grouped with other vertebrate UNC93B1 molecules, and had highest amino acid identity and similarity to zebrafish. [UNC93B1] (Mus musculus) PubMed

 15187.

Ygl7 encodes a Mg-chelatase ChlD protein. The mutational YGL7 protein acts with partial of OsChlD's function, and it could promote photosynthesis (Ygl7). (Mus musculus) PubMed

 15188.

This paper reviews the molecular basis for identifying malaria parasites lacking PfHRP2, and a set of recommended procedures to apply for future investigations for parasites lacking PfHRP2, is proposed. (Mus musculus) PubMed

 15189.

The purified P. vivax MSP-142 was characterized and found to be correctly folded and in conformation form as evident by CD spectroscopy (Mus musculus) PubMed

 15190.

the structure for NDPK was determined by using the sitting drop vapor diffusion method. In the final model, the asymmetric unit is made of three molecules, each of which consists of a four-stranded anti-parallel b-sheets and seven a-helices. (Mus musculus) PubMed

 15191.

Inactivation of SsTGase significantly reduced the virulence of Ss2 in a pig infection model. [SsTGase] (Mus musculus) PubMed

 15192.

study identified a gene encoding a novel globin-like protein (fungoglobin) which acts as a key player when the fungus adjusts to hypoxia [fungoglobin] (Mus musculus) PubMed

 15193.

This study promoted understanding of virulence regulation by EsrB in Edwardsiella tarda.[EsrB] (Mus musculus) PubMed

 15194.

A proteoliposome activity assay using the full-length SaCpaA membrane protein indicated that c-di-AMP binding alters its antiporter activity by approximately 40%. (Mus musculus) PubMed

 15195.

Importance of beta2-beta3 Loop Motion for the Increased Binding and Decreased Selectivity of the DeltaLL Mutant of the Human Papillomavirus Type 6 E2 Protein. (Mus musculus) PubMed

 15196.

Drp1 is an essential protein required for recovery from DNA damage and chromosome segregation.Drp1 is a nuclear protein and required for chromosome stability.[Drp1] (Mus musculus) PubMed

 15197.

These results suggested that activation of AmyR and MalR is regulated in a different manner, and the preceding activation of MalR is essential for the utilization of maltose as an inducer for AmyR activation.[MalR] (Mus musculus) PubMed

 15198.

MARTX toxin effector domains have differing contributions to relevant cell biological activities depending upon the cell type. (Mus musculus) PubMed

 15199.

OsAMT1;1 is a NH4 (+) transporter with relatively lower affinity to NH4 (+) (110-129 muM in oocytes and yeast cells, respectively). [OsAMT1;1] (Mus musculus) PubMed

 15200.

Kinesin-14 blocks microtubule nucleation in yeast and reveal that this inhibition is countered by the kinesin-5 protein, Cut7.[Cut7, Pkl1] (Mus musculus) PubMed

 15201.

the transcription factor early growth response 4 (egr4) is identified as a novel regulator of posterior hindbrain development in Xenopus.[Egr4] (Mus musculus) PubMed

 15202.

We found that a gene (OsASL1) encoding argininosuccinate lyase is involved in normal root development of rice. [OsASL1] (Mus musculus) PubMed

 15203.

We conclude that glucose levels are important for the survival of V. vulnificus in the host, and that this pathogen uses SidC to actively manipulate host endocrine signals, making the host environment more favorable for bacterial survival and growth. (Mus musculus) PubMed

 15204.

A 7 kDa protein p7 encoded by bacteriophage Xp10 acts as an elongation processivity factor of RNA polymerase of host bacterium Xanthomonas oryzae (p7). (Mus musculus) PubMed

 15205.

Study reports that intraperitoneal treatment with one of HN analogs, HNG, decreases body weight gain, visceral fat, and hepatic triglyceride (TG) accumulation in high-fat diet-fed mice. suggest that HN is a new player in central regulation of peripheral lipid metabolism. [Humanin, HN] (Mus musculus) PubMed

 15206.

RPA could exclude Ku from a partially resected structure with a 22-nt ssDNA tail and thus restored processing by Exo1. However, at a 40-nt tail, Ku remained stably associated at the ssDNA-dsDNA junction, and RPA simultaneously engaged the ssDNA region. (Mus musculus) PubMed

 15207.

smaller version of Cas9 in S. aureus called Cpf1 [Cpf1] (Mus musculus) PubMed

 15208.

Ablating FREP1 expression reduced Plasmodium falciparum infection in mosquitoes. [FREP1] (Mus musculus) PubMed

 15209.

Amino acid substitution at position 44 of matrix protein 2 is crucial for acquiring the highly pathogenic phenotype in chickens. [M2] (Mus musculus) PubMed

 15210.

Western blotting experiments on these SNPs loci revealed difference in CART expression among individuals with different genotypes, and individuals with lower average live backfat thickness expressed CART protein at a bit higher level than others. [CART] (Mus musculus) PubMed

 15211.

These findings provide in vivo evidence that DNA polymerase IV (Pol IV) aids in maintaining genomic stability not only by bypassing DNA lesions but also by participating in the restoration of stalled replication forks.[Pol IV] (Mus musculus) PubMed

 15212.

IpaB hydrophobic region promotes interaction with host phospholipid membrane.[IpaB] (Mus musculus) PubMed

 15213.

Data suggest that members of short chain dehydrogenase/reductase superfamily (E coli galE; human DHRS1) exhibit conserved residues and tertiary structure in active site domain that are essential for biocatalysis. [galE, UDP-galactose-4-epimerase] (Mus musculus) PubMed

 15214.

Results indicate that exogenously applied abscisic acid and gibberellins were absorbed in sufficient amounts to alter grain metabolism and impact on pre-maturity alpha-amylase: [alpha-amylase] (Mus musculus) PubMed

 15215.

A classical protein tyrosine phosphatase, an ortholog of mammalian PTP-1B, is implicated in the control of egg production in Aedes aegypti. [PTP-1B] (Mus musculus) PubMed

 15216.

OmpC role in translocation of carbapenem antibacterials through outer bacterial membrane [OmpC] (Mus musculus) PubMed

 15217.

The TORC1 effector kinase Npr1 and the upstream TORC1 regulator Npr2 control Mep2 transport activity by phospho-silencing a carboxy-terminal autoinhibitory domain.[Torc1, Npr1, Mep2] (Mus musculus) PubMed

 15218.

A striking phenotype of pkcA- was the formation of an aggregate with a central hollow, and aggregates later fragmented to form small mounds, each becoming a fruiting body.[PkcA] (Mus musculus) PubMed

 15219.

Basigin is a druggable target for host-oriented antimalarial interventions. [basigin] (Mus musculus) PubMed

 15220.

Subunit stoichiometry and interactions within eIF2B and eIF2, were investigated.[eIF2B] (Mus musculus) PubMed

 15221.

Data (including data from studies on mutant, recombinant proteins) suggest thermostability of adenylate kinase changes with amino acid substitution; enzyme stability appears to depend on local hydrophobic interactions. [adenylate kinase] (Mus musculus) PubMed

 15222.

Data suggest post-translational processing of orc6 (phosphorylation of Ser116) down-regulates nuclear import of orc6 via alterations in interaction of nuclear localization signal (NLS) with NLS receptors. [orc6; origin recognition complex subunit 6] (Mus musculus) PubMed

 15223.

AgnB is an alpha-1,3-glucanase that releases glucose from alpha-1,3-glucan substrates with a minimum degree of polymerization of 4. CfcA is a chitinase that releases dimers from the nonreducing end of chitin.[AgnB, CfcA] (Mus musculus) PubMed

 15224.

It was shown that that Wee1B-siRNA microinjection enhances the percentages of canine oocytes that reach the MI and MII stages in vitro.[Wee1B] (Mus musculus) PubMed

 15225.

differences in activity of glucoamylase from Penicillium verruculosum and Myceliophthora thermophile [glucoamylase] (Mus musculus) PubMed

 15226.

HCV NS3 protease serves as a novel TGF-b receptor ligand and enhances liver fibrosis. (Mus musculus) PubMed

 15227.

Tic40 plays role in male fertility [Tic40] (Mus musculus) PubMed

 15228.

Aprataxin hydrolyzes inosine and 6-O-methylguanosine caps, but is not adept at removing a deoxyguanosine cap (Aprataxin). (Mus musculus) PubMed

 15229.

CgTyr2 gene was differentially expressed with the highest level of expression in mantle edges [Tyr2] (Mus musculus) PubMed

 15230.

TPC3 is a new voltage-gated Na+ channel that generatesultra-long action potentials and membrane bistability.[TPC3] (Mus musculus) PubMed

 15231.

Brain proteins showing neuron-specific interactions with gamma-secretase [gamma-secretase] (Mus musculus) PubMed

 15232.

Rice Growth under drought kinase is required for drought tolerance and grain yield under normal and drought stress conditions.[Growth under drought kinase] (Mus musculus) PubMed

 15233.

Hic, a member of the pneumococcal surface protein C family (PspC11.4), interacts with vitronectin/factor H contributing to colonisation and invasive disease caused by serotype 3 pneumococci. (Mus musculus) PubMed

 15234.

In the present research, ROPN1L of the human liver fluke Opisthorchis viverrini was molecularly characterized and showed unexpected potential as a diagnostic tool. (Mus musculus) PubMed

 15235.

Data suggest that feruloyl esterase/faeB exhibits a cystine disulfide bond in active site that is essential for biocatalysis and important in substrate specificity of the enzyme. [faeB, feruloyl esterase B] (Mus musculus) PubMed

 15236.

Gbp2 and Hrb1 are key surveillance factors for the selective export of spliced mRNAs in yeast.[Gbp2, Hrb1] (Mus musculus) PubMed

 15237.

Overexpression of ZIP10 during oxidative stress activates a protective transcriptional response that results in enhanced oxidative stress resistance and increased viability.[Zip10] (Mus musculus) PubMed

 15238.

Data suggest that LPxP motif in entF (enterobactin synthase multienzyme complex component) interacts with a hydrophobic patch on the mobile C-terminal subdomain of ybdZ. [ybdZ; stimulator of entF adenylation activity] (Mus musculus) PubMed

 15239.

Data on crystal structure of DszC suggest that, in contrast to several homologous proteins, C-terminus domain (410-417) participates in stabilization of substrate-binding pocket. [DszC; DszC family monooxygenase; dibenzothiophene monooxygenase] (Mus musculus) PubMed

 15240.

VIRESCENS gene encodes a R2R3-MYB and controls fruit color. [VIRESCENS] (Mus musculus) PubMed

 15241.

These data identify bimC that is required for actin tail formation mediated by BimA from Burkholderia thailandensis. (Mus musculus) PubMed

 15242.

A repetitive DNA element regulates expression of the Helicobacter pylori sialic acid binding adhesin by a rheostat-like mechanism (Mus musculus) PubMed

 15243.

findings show V parahemolyticus colonization and virulence depend upon VopV, a bacterial protein that is transferred into host epithelial cells; VopV induces rearrangement of the apical epithelial cell membrane, including elimination of microvilli [VopV] (Mus musculus) PubMed

 15244.

There were significant delays in senescence and reductions in grain Zn and Fe content in gpc1 but not gpc2 mutants. There was a larger proportion of senescence-regulated genes among the GPC1 than among the GPC2 regulated genes.[GPC1,GPC2] (Mus musculus) PubMed

 15245.

The function of OsUAM3 is important for synthesis of arabinan side chains of rhamnogalacturonan I and is required for reproductive developmental processes.[OsUAM3] (Mus musculus) PubMed

 15246.

Study identified and characterized the Botrytis cinerea pmr1 gene, the closest homolog of yeast PMR1; authors hypothesized that bcpmr1 also encodes a Ca(2+)/Mn(2+)-ATPase that plays an important role in the protein glycosylation pathway. [PMR1] (Mus musculus) PubMed

 15247.

propose that oxidatively modified cholesterol like 27OHChol, rather than cholesterol, is responsible for sustained expression of CXCL8 in monocytes/macrophages in atherosclerotic arteries [CXCL8] (Mus musculus) PubMed

 15248.

We conclude that colibactin contributes to the capacity of E. coli K1 to colonize the neonatal gastrointestinal tract and to cause invasive disease in the susceptible neonate. (Mus musculus) PubMed

 15249.

host differences in immune responses to saeRS-regulated antigens may determine whether S. aureus infection elicits protective or nonprotective immunity against recurrent infection. (Mus musculus) PubMed

 15250.

Rapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys. (Mus musculus) PubMed

 15251.

MF25(Bol018697) is a novel polygalacturonase gene involved in pollen development of Brassica oleracea. [MF25] (Mus musculus) PubMed

 15252.

Promoter DNA methylation plays a novel enhancing role in conditioning high-level of induced expression of the Pib gene in times of M. grisea infection, and its conferred resistance to the pathogen.[Pib] (Mus musculus) PubMed

 15253.

Despite a normal growth rate under in vitro growth conditions, the orlA mutant was virtually avirulent in two distinct murine models of invasive pulmonary aspergillosis.[orlA] (Mus musculus) PubMed

 15254.

Colicin N and M13 phage protein G3p compete with TolB for a binding site on TolA. [ColN] (Mus musculus) PubMed

 15255.

bacterial type 1A topos maintain the stability of the genome (i) by preventing over-replication originating from oriC (topo I alone) and R-loops and (ii) by acting with RecQ. (Mus musculus) PubMed

 15256.

alpha-Hemolysin secreted from S. aureus, particularly the EV-associated form, induces both skin barrier disruption and AD-like skin inflammation (Mus musculus) PubMed

 15257.

findings suggest that Nsp9 and Nsp10 together contribute to the fatal virulence of HP-PRRSV emerging in China, helping to elucidate the pathogenesis of this virus. (Mus musculus) PubMed

 15258.

Activation of an ancient duplicated MYB gene PpMYB10.4 in the Gr interval on LG 6, which represents a novel branch of anthocyanin-activating MYB genes in Rosaceae, is able to activate leaf red coloration in peach.[ (Mus musculus) PubMed

 15259.

Biochemical and structural data indicated that FTN_1133 displayed distinct characteristics from other thiol dependent peroxidases and suggested that FTN_1133 is not directly involved in hydroperoxide detoxification. [FTN_1133 ] (Mus musculus) PubMed

 15260.

The BldM-WhiI system thus exemplifies the potential of response regulator heterodimer formation as a mechanism to expand the signaling capabilities of bacterial cells (Mus musculus) PubMed

 15261.

RNA sequence analysis reveals a six-gene SoxR regulon in Streptomyces coelicolor. [SoxR] (Mus musculus) PubMed

 15262.

This study confirms that the SdrI protein of Staphylococcus saprophyticus is a crucial factor for surface hydrophobicity.[SdrI] (Mus musculus) PubMed

 15263.

Differential PfEMP1 expression is associated with cerebral malaria pathology (Mus musculus) PubMed

 15264.

the largest subunit of RNA pol I TbRPA1 was SUMOylated in a TbSIZ-dependent manner. (Mus musculus) PubMed

 15265.

As part of our goal to evaluate small-molecule binding to gp41, we have redesigned the reverse hairpin sequences and the methods used to prepare them, and have obtained several constructs with high levels of overexpression (Mus musculus) PubMed

 15266.

The terminal 20 aa at the C-terminus of PA-X plays a role in enhancing viral replication and contributes to virulence. [PA-X] (Mus musculus) PubMed

 15267.

GUS reporter gene expression responded to heat in different tissues and at different development stages when driven by POsACO1. The heat response element resided in a 9-bp region between -1132 and -1124, a sequence that contains a W-box motif.[ACO1] (Mus musculus) PubMed

 15268.

results indicate that Sxi2a-Sxi1alpha regulates a diverse set of genes that include those at the junctions among sexual development, starvation and virulence [Sxi2a, Sxi1a] (Mus musculus) PubMed

 15269.

The prevalence of K13-propeller and FP2 polymorphisms did not increase over time, and was not associated with either time since prior receipt of an ACT or the persistence of parasites >/=2 days following treatment with an ACT. (Mus musculus) PubMed

 15270.

Detailed functional and structural analyses of CCRs from Medicago truncatula and Petunia hybrida and of an atypical CAD (CAD2) from M. truncatula, are described.[CAD2, CCR] (Mus musculus) PubMed

 15271.

Trafficking of tonoplast-targeted proteins in infected symbiotic cells is also altered, as shown by retargeting of the aquaporin TIP1g from the tonoplast membrane to the symbiosome membrane.[TIP1g] (Mus musculus) PubMed

 15272.

we uncover that SAS-1 is related to C2CD3, a protein required for complete centriole formation in human cells and affected in a type of oral-facial-digital (OFD) syndrome. (Mus musculus) PubMed

 15273.

we defined a network of proteins consisting of two Ste20-related kinases, the small GTPase RAS-2 and the adenylate cyclase capping protein CAP-1 that function upstream of the MAK-2 pathway (Mus musculus) PubMed

 15274.

These results provide further evidence implicating IscR in bacterial virulence and suggest that IscR may represent a more general regulator mediating the iron response in enteropathogens.[IscR] (Mus musculus) PubMed

 15275.

The gene encoding proline dehydrogenase is 1674 bp in length with a open reading frame of 1485 bp. [proline dehydrogenase] (Mus musculus) PubMed

 15276.

potential mechanisms of Atf1 and Atf2 membrane association, are investigated.[Atf1, Atf2] (Mus musculus) PubMed

 15277.

OsHO2 has a potential regulatory role for tetrapyrrole biosynthesis in rice. [OsHO2] (Mus musculus) PubMed

 15278.

PeNHX3 mediated Na+, K+ and Li+ transport in a yeast growth assay.[PeNHX3] (Mus musculus) PubMed

 15279.

In fact, these result proposed that the ABCCC type CagA protein can induce the intestinal metaplasia, IL-8, perturbation of Crk adaptor proteins, anti-apoptotic effect and carcinogenic effect more significantly than ABC type.[CagA] (Mus musculus) PubMed

 15280.

This result suggests that Himetobi P virus VP1 potentially facilitates the accumulation of rice stripe virus in small brown planthopper. (Mus musculus) PubMed

 15281.

YjjN is indeed an L-galactonate dehydrogenase having activity also for L-gulonate [yjjN] (Mus musculus) PubMed

 15282.

this study identified a new meiosis-specific protein Npg1, and found that it was involved in the efficient formation of spores and spore viability. [Npg1] (Mus musculus) PubMed

 15283.

Treg cells from Dbc1-deficient mice were more resistant to inflammation-mediated abrogation of Foxp3 expression and function [deleted in breast cancer 1] (Mus musculus) PubMed

 15284.

Crystal structure of CbsA reveals a unique homodimeric assembly facilitated by the C-terminal domains in the dimer.[CbsA] (Mus musculus) PubMed

 15285.

RAD18 as a critical embryonic checkpoint-inhibiting factor and RAD18 deregulation may have unexpected oncogenic potential. [RAD18] (Mus musculus) PubMed

 15286.

The article presents pulse Electron Paramagnetic Resonance studies of (13)C and (15)N-labeled H-cluster of the cyanide ligands of [FeFe] hydrogenase HydA. [HydA] (Mus musculus) PubMed

 15287.

The role of Rp1-D21 in the hypersensitive response of Z. mays and its transport in cells are reported.[Rp1-D21] (Mus musculus) PubMed

 15288.

Aire's collaboration with the bromodomain-containing protein, Brd4, uncovered correspondence between those genes induced by Aire and those inhibited by a small-molecule bromodomain blocker.[P-TEFb] (Mus musculus) PubMed

 15289.

The bacterial adhesin FimH was studied to address the role of the inactive conformation of the pocket for initiating binding.[FimH] (Mus musculus) PubMed

 15290.

In sigma(70)-dependent pausing, the elemental pause acts primarily to modulate the rate at which complexes attempt to disengage the sigma(70):DNA interaction.[Sigma factor] (Mus musculus) PubMed

 15291.

dynamic nuclear polarization applied to (15)N-labeled channelrhodopsin-2 carrying 14,15-(13)C2 retinal reconstituted into lipid bilayers, is reported.[Channelrhodopsin-2] (Mus musculus) PubMed

 15292.

SpyA mediates ADP-ribosylation of SpyB. SpyB and SpyA are translationally coupled. (Mus musculus) PubMed

 15293.

some bacterial Sco proteins may have biochemical properties that are distinct from those of mitochondrial Sco proteins[PrrC] (Mus musculus) PubMed

 15294.

analysis of engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis [hrdB] (Mus musculus) PubMed

 15295.

The authors identified a specific interaction between the human small GTPase Rab2 and a Brucella spp. protein named RicA.[RicA] (Mus musculus) PubMed

 15296.

The study presents the biochemical properties of a key enzyme 6-hydroxy-3-succinoylpyridine hydroxylase involved in the fused nicotine degradation pathway of the pyridine and pyrrolidine pathways. [6-hydroxy-3-succinoylpyridine hydroxylase hydroxylase] (Mus musculus) PubMed

 15297.

The mucin-like region of HSV-1 gC is involved in the modulation of the glycosaminoglyacn-binding activity.[gC] (Mus musculus) PubMed

 15298.

The binding affinity and 1:1:1 stoichiometry of the FtsQpBpLp complex and the FtsQpBp subcomplex were determined in complementary surface plasmon resonance, analytical ultracentrifugation, and native mass spectrometry experiments.[FtsQ, FtsB, FtsL] (Mus musculus) PubMed

 15299.

ammonia transfer along two intramolecular tunnels in Staphylococcus aureus glutamine-dependent amidotransferase [GatCAB] (Mus musculus) PubMed

 15300.

BmPrx5 acts as an antioxidant enzyme to protect the silkworm from oxidative damage induced by bacterial infection (Mus musculus) PubMed

 15301.

Dopamine modulation of octanol avoidance requires NMR-1.[NMR-1] (Mus musculus) PubMed

 15302.

The reconstitution of a mispair-dependent Mlh1-Pms1 endonuclease activation reaction, is reported.[Mlh1, Pms1] (Mus musculus) PubMed

 15303.

The Sdj1-L169P fission yeast orthologue of DJ1-L166P is misfolded, associated with chaperones, and degraded via two ubiquitin-proteasome dependent pathways. [Sdj1] (Mus musculus) PubMed

 15304.

Mutational analysis and molecular dynamics simulation identified a specific residue pair in the first helix of ScaADoc, as well as a glutamate near the C-terminus to be essential for cohesin binding. [ScaADoc] (Mus musculus) PubMed

 15305.

Target of rapamycin (TOR) signaling stimulates ribosomal DNA amplification in budding yeast.[TOR] (Mus musculus) PubMed

 15306.

This result is important because it shows that the surface of the Hsp70 chaperone provides an aggregation-free environment able to support part of the search for the native state.[Hsp70] (Mus musculus) PubMed

 15307.

crystal structures of Thermus thermophilus CarH in all three relevant states: in the dark, both free and bound to operator DNA, and after light exposure [CarH] (Mus musculus) PubMed

 15308.

lfd-2 (for late fusion defect-2) mutant showed a calcium-dependent cell lysis phenotype. lfd-2 encodes a protein with a Fringe domain and showed endoplasmic reticulum and Golgi membrane localization. (Mus musculus) PubMed

 15309.

The first crystal structures of both the choline-bound and choline-free forms of CutC were determined and discovered that binding of choline at the ligand-binding site triggers conformational changes in the enzyme structure.[CutC] (Mus musculus) PubMed

 15310.

The crystal structure of the TrmD homodimer in complex with a substrate tRNA and an S-adenosyl-l-methionine analog.[TrmD] (Mus musculus) PubMed

 15311.

The crystal structure of the TrmD homodimer in complex with a substrate tRNA and an S-adenosyl-l-methionine analog.[TrmD] (Mus musculus) PubMed

 15312.

catalytic chemical steps of MTANs from E coli and Vibrio cholera [MTAN] (Mus musculus) PubMed

 15313.

catalytic chemical steps of MTANs from E coli and Vibrio cholera [MTAN] (Mus musculus) PubMed

 15314.

A residue-level depth potential was applied for beta-barrel membrane proteins to the complete redesign of the lipid-facing surface of Escherichia coli OmpA.[OmpA] (Mus musculus) PubMed

 15315.

EspJ inhibits autophosphorylation of host Src and phosphorylation of the Src substrates Tir and FcgammaRIIa. [EspJ] (Mus musculus) PubMed

 15316.

CchA, MidA, and YvcA play a role in A. fumigatus calcium homeostasis and virulence.[Mid1, Cch1, Yvc1] (Mus musculus) PubMed

 15317.

This structure, determined to 2.15 A resolution, shows that dimethylsulfoniopropionate lyase is a homodimeric metalloprotein with a binuclear center of two metal ions located 2.7 A apart in the active site of the enzyme. [dimethylsulfoniopropionate lyase] (Mus musculus) PubMed

 15318.

insights into why the number of basic amino acids in the GAG-binding site of DBPA may not be the only factor determining GAG affinity of proteins (decorin binding protein A (DBPA) (Mus musculus) PubMed

 15319.

Use molecular dynamics simulation to examine role of methionine sulfoxide in function of WrbA protein from E.coli BL21. (Mus musculus) PubMed

 15320.

negative regulator of arbuscule formation by hampering auxin perception in arbuscule-containing cells [miR393] (Mus musculus) PubMed

 15321.

negative regulator of arbuscule formation by hampering auxin perception in arbuscule-containing cells [miR393] (Mus musculus) PubMed

 15322.

The study provide a structural model for 5S RNP recruitment to the pre-60S particle and explains why removal of Rpf2-Rrs1 is necessary for rearrangements to drive 60S maturation(Rpf2 and Rrs1). (Mus musculus) PubMed

 15323.

Structural studies show that MRB1590 is dimeric and contains a central ABC-ATPase fold embedded between novel N- and C-terminal regions (MRB1590). (Mus musculus) PubMed

 15324.

Human herpesvirus 1 ICP6 interacts with mouse RIP1/RIP3 through its RHIM domain and forms dimers/oliogmers by its C-terminal R1 domain.[ICP6] (Mus musculus) PubMed

 15325.

Herpes simplex virus 1- and 2 ICP6 and ICP10 proteins prevent necroptosis in human cells by inhibiting the interaction between receptor-interacting protein kinase 1 (RIP1) and RIP3, a key step in tumor necrosis factor-induced necroptosis.[ICP6 and ICP10] (Mus musculus) PubMed

 15326.

Sequence analysis and activity tests indicated that XfHNL exhibits an alpha/beta-hydrolase fold and could be classified as a member of the family of FAD-independent hydroxynitrile lyase. [hydroxynitrile lyase] (Mus musculus) PubMed

 15327.

Despite nucleotide sequence variation in exon of AsteObp1, nearly 100% identity was observed at the amino acid level among the three biological forms. (Anopheles stephensi odorant binding protein 1) (Mus musculus) PubMed

 15328.

In silico molecular docking simulations were conducted using the modules of the programs Glide-SP, Glide-XP and Autodock with O-acetyl-L-serine sulfhydrylase (OASS) enzyme-a promising target for inhibiting the growth of Entamoeba histolytica (Mus musculus) PubMed

 15329.

MiR-181a regulates lipid metabolism via IDH1 (Mus musculus) PubMed

 15330.

The study demonstrates that sigmaNS assembles into stable elongated hexamers in vitro, which bind single-stranded nucleic acids with high affinity, but little sequence specificity (sigmaNS). (Mus musculus) PubMed

 15331.

PhoExo I utilizes an RNase H-like active site and possesses a 3'-OH recognition site approximately 9 A away from the active site, which enables cleavage at every two nucleotides (PhoExo I). (Mus musculus) PubMed

 15332.

two proteins-homologs of Lis1 and Clip170-are sufficient to couple dynein to Kip2, a plus-end-directed kinesin.[Dynein, Kip2] (Mus musculus) PubMed

 15333.

The authors discovered that it is not a decarboxylase per se but an ATP-dependent enzyme, mevalonate-3-kinase (M3K), which catalyzes the phosphorylation of MVA to mevalonate-3-phosphate.[mevalonate-3-kinase] (Mus musculus) PubMed

 15334.

This research provides molecular and morphological data on the regulation of gonadotropin-inhibitory hormone (GnIH) in the reproductive development of male pigs [GnIH] (Mus musculus) PubMed

 15335.

functions as a negative regulator of immune signaling dependent on complex formation in the plasma membrane [Pti1a] (Mus musculus) PubMed

 15336.

These results provided evidence for the function of CodY, by which this strain coordinately regulates its various metabolic pathways so as to adapt to the milk environment.[CodY] (Mus musculus) PubMed

 15337.

RNA binding studies demonstrated that L10(L12)4 stabilizes the anti-antiterminator structure, while in vitro transcription results indicated that L10(L12)4 promotes termination (ribosomal protein L10 and ribosomal proteins L12). (Mus musculus) PubMed

 15338.

Arginine 112 of NS5A plays a crucial role in the modulation of HCV life cycle. [NS5A] (Mus musculus) PubMed

 15339.

A protofilament doublet is essential for MreB's function in cell shape maintenance.[MreB] (Mus musculus) PubMed

 15340.

Adjacent, horizontally oriented middle domains form head-to-tail contacts and repress ClpB activity by preventing Hsp70 interaction.[ClpB, Hsp70] (Mus musculus) PubMed

 15341.

A protofilament doublet is essential for MreB's function in cell shape maintenance.[MreB] (Mus musculus) PubMed

 15342.

the structure of tetrameric human metapneumovirus M2-1, is reported.[M2-1] (Mus musculus) PubMed

 15343.

Study reports the crystal structures of SaCas9 in complex with a single guide RNA (sgRNA) and its double-stranded DNA targets, containing the 5'-TTGAAT-3' PAM and the 5'-TTGGGT-3' PAM, at 2.6 and 2.7 A resolutions, respectively. The structures revealed the mechanism of the relaxed recognition of the 5'-NNGRRT-3' PAM by SaCas9 (Mus musculus) PubMed

 15344.

Our analysis revealed that NdgR is a global transcriptional regulator involved in the regulation of branched-chain amino acids biosynthesis and sulphur assimilation (Mus musculus) PubMed

 15345.

These data suggest that Pfs promotes autolysis-dependent release of eDNA and biofilm formation in Staphylococcus aureus.[Pfs] (Mus musculus) PubMed

 15346.

The results confirm that avirulence/virulence determinants of SMV on Rsv4-genotype soybean reside exclusively on P3.[P3] (Mus musculus) PubMed

 15347.

BcSkn7 plays an important role in the regulation of vegetative differentiation and in the response to various stresses in B. cinerea.[BcSkn7] (Mus musculus) PubMed

 15348.

[MscL] MscL functions as a non-specific ion channel, and it participates in regulation of cell volume under temperature-stress conditions. (Mus musculus) PubMed

 15349.

SUMO chain-modified Pli1 is targeted for proteasomal degradation by the concerted action of a SUMO-targeted ubiquitin ligase (STUbL) and Cdc48-Ufd1-Npl4. (Mus musculus) PubMed

 15350.

PSK1,PSK4, and PSK5 are not induced at the early stage of root nodulation, but highly expressed in enlarged symbiotic cells of nodules. [psk1] [psk4] [psk5] (Mus musculus) PubMed

 15351.

Overall, a greater prevalence of MAD 20 alleles of msp-1 and increased serum TNF-alpha and CXCL9 levels were associated with severe outcome in malaria. (Mus musculus) PubMed

 15352.

BpsB is critical for the formation and complex architecture of B. bronchiseptica biofilms. (Mus musculus) PubMed

 15353.

Pim kinase may represent a new host factor for HCV entry. Pim1 is an oncogenic serine/threonine kinase. NS5A protein physically interacts with Pim1 and contributes to Pim1 protein stability. (NS5A) (Mus musculus) PubMed

 15354.

these results demonstrated that no toxic effect was observed in the feeding rat with rice flour from Bacillus thuringiensis (Bt) transgenic rice line (mfb-MH86) expressing a synthetic cry1Ab gene (Mus musculus) PubMed

 15355.

The TolB-Pal trans-envelope complex from Xylella fastidiosa reveals a dynamic and coordinated protein expression profile during the biofilm development process. [Pal] (Mus musculus) PubMed

 15356.

It is concluded that cpdB is involved in long-term colonization of Salmonella Pullorum in the chicks' cecum and internal organs.[cpdB] (Mus musculus) PubMed

 15357.

The results demonstrate that trypanosomal PEX16 is essential for glycosome biogenesis and thereby, provides a potential drug target for sleeping sickness and related diseases. (Mus musculus) PubMed

 15358.

Hippo signaling can modulate Notch signaling outputs, and components of the Hippo and Notch pathways physically interact.[Hi[[o] (Mus musculus) PubMed

 15359.

ribB FMN riboswitch controls expression of the essential gene ribB coding for the riboflavin biosynthetic enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase (RibB; EC 4.1.99.12) (Mus musculus) PubMed

 15360.

The N-terminal domain 1 and the core of domain 2 share the same fold despite a very low level of sequence identity, and their surface-charge distributions are different. (Mus musculus) PubMed

 15361.

Determined the first crystal structure of FMN-bound DszC, and found that two distinct conformations occur in the loop region (residues 131-142) adjacent to the active site. (DszC (DBT monooxygenase)) (Mus musculus) PubMed

 15362.

the open form of ApAAP corresponds to a scavenger of possible substrates, the actual cleavage of which only takes place if the enzyme is able to re-close. (Mus musculus) PubMed

 15363.

Molecular docking simulation after site directed mutagenesis showed that Lys68/Lys69 residues of Algp7 play probably an important role in alginate binding. [Algp7]. (Mus musculus) PubMed

 15364.

results suggest that rice PAO1 is the functional ortholog of Arabidopsis PAO5 (polyamine oxidase 1, rice) (Mus musculus) PubMed

 15365.

The crystal structure of the H. orenii glycosidase GH43. [GH43] (Mus musculus) PubMed

 15366.

The cloned Dlf1 gene encodes a WRKY transcription factor (OsWRKY11). It acts as a transactivator to downregulate Ehd2/RID1/OsId1 in the signal transduction pathway of flowering and plays an important role in the regulation of plant height. Dlf1. (Mus musculus) PubMed

 15367.

MST11 phosphorylation of S453 and S458 play regulatory role in Mst11 activation and infection-related morphogenesis. (Mus musculus) PubMed

 15368.

AvrBs2 is an essential virulence factor that contributes to X. oryzae pv. oryzicola virulence through inhibiting defense responses and promoting bacterial multiplication in monocot rice. [AvrBs2] (Mus musculus) PubMed

 15369.

We determined that the deletion of RNase II significantly affected 187 transcripts, while deletion of RNase R affects 202 transcripts and deletion of PNPase affected 226 transcripts (Mus musculus) PubMed

 15370.

An alternatively spliced heat shock transcription factor, HSFA2dI, functions in the heat stress-induced unfolded protein response in rice (HSFA2dI). (Mus musculus) PubMed

 15371.

Data suggest that Viral microRNA hcmv-miR-UL112 subverts innate immunity by downregulating type I interferons IFN-alpha and IFN-beta signaling to inhibit natural killer (NK) cell cytotoxicity. (Mus musculus) PubMed

 15372.

functional characterization of a C-7 cholesterol desaturase from Tetrahymena thermophila [DES7] (Mus musculus) PubMed

 15373.

These findings suggest that EV71 induces S-phase cell cycle arrest in infected cells via non-structural protein 3D, which may provide favorable conditions for virus production.[3D] (Mus musculus) PubMed

 15374.

NfBGL1 has broad substrate specificity including glucosidase, cellobiase, xylanase and glucanase activities, and displayed preference for hydrolysis of beta-1,2 glycosidic bond. [NfBGL1] (Mus musculus) PubMed

 15375.

Substitution of Cys134 by an Ala results in accumulation of the monomer, and reduces SpoIIIJ function in vivo. Therefore, SpoIIIJ activity in vivo appears to require dimer formation. [SpoIIIJ] (Mus musculus) PubMed

 15376.

MBF contribute to L. rhamnosus host colonization via mucin and ECM protein binding [MBF] (Mus musculus) PubMed

 15377.

The optimal pH and temperature for the recombinant phytase activity is achieved at 7.0 and 55 degrees C.[PhyA] (Mus musculus) PubMed

 15378.

Data show that the elicitor-encoding gene mohrip2 (JQ815555) was cloned and the 459-bp gene encodes a 152-residue polypeptide that contains an 18-residue signal peptide [MoHrip2] (Mus musculus) PubMed

 15379.

ZmGns was also induced by most abiotic stresses tested and growth hormones including salicylic acid.[ZmGns] (Mus musculus) PubMed

 15380.

Data show that transcription factor MaBSD1 could activate the expression of two cell wall modification-related genes, MaEXP1/2, via directly interacting with their promoters [MaBSD1, MaEXP1 and MaEXP2] (Mus musculus) PubMed

 15381.

Data indicate that B-box protein, MdCOL11, was differentially expressed in all the tissues with the highest expression in the petal [MdCOL11] (Mus musculus) PubMed

 15382.

role of Tyr170 in DMA binding by family 4 uracil-DNA glycosylase from Sulfolobus tokodaii [family 4 uracil-DNA glycosylase] (Mus musculus) PubMed

 15383.

Data show that constitutive expression of aminocyclopropane-1-carboxylate oxidase gene, TaACO1 in Arabidopsis increased AtMYB15 expression: [ACO1] (Mus musculus) PubMed

 15384.

The Emp6+gene function is required independently in both the embryo and endosperm.[Emp6] (Mus musculus) PubMed

 15385.

NCgl2759 is a novel trehalose corynomycolates (TMCM) mycolyl acetyltransferase (TmaT) that regulates transport of TMCM and is a potential drug target in pathogenic species.[TmaT] (Mus musculus) PubMed

 15386.

The formylglycinamide ribonucleotide amidotransferase (PurL) ammonia pathway has been elucidated by combining 3D-RISM theory with experiment. [PurL] (Mus musculus) PubMed

 15387.

Conformational control of DNA target cleavage by CRISPR-Cas9 [Cas9] (Mus musculus) PubMed

 15388.

The CASA gene was isolated and cloned into the original expression vector, resulting in an effective E. coli BL2l(DE3) pMD0107 strain producing CASA. (Mus musculus) PubMed

 15389.

The crystal structure of recombinant Srr-1-K4BD(485-642) and its possible mode of interaction with K4 through docking studies, are reported.[Srr-1] (Mus musculus) PubMed

 15390.

Optimal xylanase activity was observed at pH 6.0, and enzyme remained active within pH 4.0-10.0 and at a temperature below 70 degrees C. [XynH1] (Mus musculus) PubMed

 15391.

cagA-positive H. pylori is highly prevalent in southern Mexico, and all CagA variants were of the western type; the cagA alleles that code for EPIYA-ABCC motif patterns are associated with peptic ulcers and gastric cancer [CagA] (Mus musculus) PubMed

 15392.

Six miRNA families, osa-miR159, osa-miR160 osa-miR164, osa-miR167, osa-miR172 and osa-miR1848, targeting the genes encoding APETALA2, SIP19, auxin response factors and NAC transcription factors (Mus musculus) PubMed

 15393.

Using an HPLC-based MalQ enzyme assay, the study could demonstrate that the equilibrium concentration of maltodextrin products depends on the length of the initial substrate; with increasing numbers of glycosidic bonds, less glucose is formed. [MalQ] (Mus musculus) PubMed

 15394.

potential role of apple AMADHs in 4-aminobutyrate and beta-alanine production [MdAMADH1] [MdAMADH2] (Mus musculus) PubMed

 15395.

Data suggest that reactive oxygen species produced via plasma membrane NADPH oxidase regulates anthocyanin synthesis [plasma membrane NADPH oxidase] (Mus musculus) PubMed

 15396.

yijE gene is involved in response to cystine in E. coli [yijE] (Mus musculus) PubMed

 15397.

PkcA is involved in CWI maintenance through the transcriptional regulation of cell wall-related genes [PkcA][RlmA] (Mus musculus) PubMed

 15398.

The results are showing that S. gordonii ArcD modulates not only alkali and energy production but also interspecies interaction with F. nucleatum, thus initiating a middle stage of periodontopathic biofilm formation, by metabolic cross-feeding. [ArcD] (Mus musculus) PubMed

 15399.

high throughput screening campaign identified thieno[2,3-b]pyridines as a new class of PfGSK-3 inhibitors (Mus musculus) PubMed

 15400.

nteraction between pGyrB and a bis-pyridylurea inhibitor [GyrB] (Mus musculus) PubMed

 15401.

The production of NDM-1 in strain 44551 contributed the majority to its high resistance to carbapenems, while the blaOXA-58 stayed silent most likely due to the lack of an upstream promoter to drive its transcription (Mus musculus) PubMed

 15402.

Zfs1 bound to the ideal mammalian tristetraprolin binding site with high affinity, and Zfs1 was associated with target transcripts after co-immunoprecipitation; biochemical activities of these proteins in fungi are highly conserved, but Zfs1-like proteins may target different transcripts in each species [Zfs1] (Mus musculus) PubMed

 15403.

Characterization and expression analyses of two plastidic enolase genes in rice [Eno1][Eno3] (Mus musculus) PubMed

 15404.

study presents the first evidence that some functions of the BcNoxA complex are indeed linked to the endoplasmic reticulum (ER), while others clearly require export from the ER [NoxD] (Mus musculus) PubMed

 15405.

PilE4:ICAM-1 interaction unfolded here may provide a new perspective on molecules involved in the adhesion of extracellular form of Francisella to endothelial cells.[PilE4] (Mus musculus) PubMed

 15406.

The majority of the L2 protein becomes accessible on the cytosolic side of intracellular membranes in order to interact with cytosolic factors to facilitate vesicular trafficking. [L2] (Mus musculus) PubMed

 15407.

The genetic variability of Seg-10/NS3 differentially modulates BTV replication kinetics in a host-specific manner. [NS3] (Mus musculus) PubMed

 15408.

Structural insights into stereospecific reduction of alpha, beta-unsaturated carbonyl substrates by old yellow enzyme from Gluconobacter oxydans [Gox0502] (Mus musculus) PubMed

 15409.

The VrrA small non-coding RNA controls a stationary phase survival factor Vrp of Vibrio cholerae. [Vrp] (Mus musculus) PubMed

 15410.

This investigation reveals that ahpC1 is the chief peroxidase gene that acts against organic peroxides in Vibrio parahaemolyticus and that the function of the ahpC genes is influenced by incubation temperature.[ahpC1, ahpC2] (Mus musculus) PubMed

 15411.

Closed-loop model of mRNA translation is prevalent for eIF4E/4G-bound but unexpectedly sparse for PAB1-bound mRNAs. [eIF4G] (Mus musculus) PubMed

 15412.

The results show that only EIF4G3, with its cap binding partner EIF4E4, plays a major role in translational initiation. [EIF4G] (Mus musculus) PubMed

 15413.

PfEMP1 and KAHRP co-localize to membrane knobs of P. falciparum infected erythrocytes.[PfEMP1, KAHRP] (Mus musculus) PubMed

 15414.

The results show that only EIF4G3, with its cap binding partner EIF4E4, plays a major role in translational initiation. [EIF4G] (Mus musculus) PubMed

 15415.

The fdeC gene encodes a protein that is expressed at the cell surface and promotes biofilm formation under continuous-flow conditions and is repressed by the global regulator H-NS.[fdeC] (Mus musculus) PubMed

 15416.

These results thus demonstrated that the presence of additional carbon sources promotes competence development and natural transformation by reducing cyclic AMP receptor (CRP) and, thus, derepressing rpoS.[CRP; rpoS] (Mus musculus) PubMed

 15417.

Two structures of Sulfolobus solfataricus Ard1 (SsArd1), a member of the NatA family, at 2.13 and 1.84 A, are presented.[Ard1] (Mus musculus) PubMed

 15418.

Results suggest that thioredoxin peroxidase-1 (TPx-1) may be involved in merozoite formation during liver schizont development [TPx-1] (Mus musculus) PubMed

 15419.

Together, DidA and SidA inhibit division, such that cells lacking both inhibitors divide prematurely following DNA damage, with lethal consequences. [DidA] (Mus musculus) PubMed

 15420.

Isolated 100-kDa CyaA-RTX (Repeat-in-ToXin) subdomain retains functionality for binding to target erythrocytes. [CyaA] (Mus musculus) PubMed

 15421.

The control of cg1623 by the DtxR-type regulator MntR represents the first example of a predicted ZIP family protein that is regulated in a manganese-dependent manner in bacteria.[MntR, cg1623] (Mus musculus) PubMed

 15422.

Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis. (Mus musculus) PubMed

 15423.

OsPUB15 physically interacted with the kinase domain of PID2 (PID2K) in vitro and in vivo and the ARM repeat domain of OsPUB15 was essential for the interaction. PID2K possessed kinase activity and was able to phosphorylate OsPUB15.[PID2] (Mus musculus) PubMed

 15424.

Rice MEL2 is involved in the translational regulation of key meiotic genes on 3'-UTRs to achieve the faithful transition of germ cells to meiosis. [MEL2] (Mus musculus) PubMed

 15425.

[alpha-dioxygenase] the unique alpha-DOX of the primitive land plant P. patens, although apparently not crucial, participates both in development and in the defense response against pathogens (Mus musculus) PubMed

 15426.

cloned and characterized a glutathione peroxidase-like thioredoxin peroxidase (TPxGl) and confirmed it is the functional ortholog of the corresponding P. falciparum enzyme; data provides new insights into the structure and ubiquitous expression of Plasmodium TPx(Gl) [TPxG1] (Mus musculus) PubMed

 15427.

These data suggest that the callose synthase encoded by GSL5 plays a vital role in microspore development during late meiosis and is essential for male fertility in rice.[GSL5] (Mus musculus) PubMed

 15428.

High-level induction of cyp-35A family genes by caffeine exposure can be fatal to the development of early-stage larvae. [cyp-35A] (Mus musculus) PubMed

 15429.

This paper describes the first comprehensive study on the isolation, purification, characterization, cloning, immobilization, protein modeling, and 3D structure determination of novel alkaline metalloproteases from isolated strain of P. aeruginosa (Mus musculus) PubMed

 15430.

propose that the GlnB protein acts as a 2-oxoglutarate-sensitive dissociable regulatory subunit of acetyl-CoA carboxylase enzyme [GlnB] (Mus musculus) PubMed

 15431.

The peptide sequence of acidocin B was found to consist of 58 amino acids with a molecular mass of 5,621.5 Da. The sequence of the acidocin B biosynthetic gene cluster showed high nucleotide sequence similarity to that of gassericin A.[acdB] (Mus musculus) PubMed

 15432.

H-NS family protein Pmr, NdpA-like protein Pnd, and HU-like protein Phu act synergistically to affect incompatibility P-7 group plasmid pCAR1 replication, maintenance, and transfer, as well as to alter the host metabolic phenotype.[pmr,pnd,phu] (Mus musculus) PubMed

 15433.

P. alcaligenes was able to methylate arsenite rapidly to dimethylarsenate and small amounts of trimethylarsenic oxide. An arsenite S-adenosylmethionine methyltransferase, PaArsM, shares low similarities with other reported ArsM enzymes (<55%).[PaArsM] (Mus musculus) PubMed

 15434.

This study provides strong evidence a) that TonB-dependent, HemR-mediated iron acquisition is important for maintenance of symbiont homeostasis in tsetse fly, and b) for expression of bacterial high-affinity iron acquisition genes in symbionts.[TonB,HemR] (Mus musculus) PubMed

 15435.

Human macrophages exposed to 50 ng of amylosin ml(-1) secreted high levels of cytokines interleukin-1beta (IL-1beta) and IL-18 within 2 h, indicating activation of the NLRP3 inflammasome, an integral part of the innate immune system.[amylosin] (Mus musculus) PubMed

 15436.

This study showed that diffusible signal factor (DSF) is not the sole DSF family signal produced by X. campestris pv. campestris. It is shown here that strain Xc1 produces at least two other DSF family signals, BDSF and DSF-II.[DSF,BDSF,DSF-II] (Mus musculus) PubMed

 15437.

identification of an AHL-degrading gene homolog (designated aiiT) in the genome of T. marianensis JCM 10246 [aiiT] (Mus musculus) PubMed

 15438.

the formation of the Gins51 tetramer is necessary for MCM activation, and the disordered linker region between the two domains is critical for the functional complex formation [gins51] (Mus musculus) PubMed

 15439.

[REC-1] mutation of the CDK consensus sites in REC-1 compromises meiotic crossover distribution in vivo (Mus musculus) PubMed

 15440.

Molecular dynamics simulations were performed to explore the dynamic binding mechanism of xa5 and avrxa5.[avrxa5] (Mus musculus) PubMed

 15441.

Molecular dynamics simulations were performed to explore the dynamic binding mechanism of xa5 and avrxa5.[Xa5] (Mus musculus) PubMed

 15442.

IL-1beta and interferon type 1 increased atrogin-1 mRNA expression whereas IGF-1 suppressed atrogin-1 expression.[Atrogin 1] (Mus musculus) PubMed

 15443.

the vacuolar glucose transporter OsSWEET2b from rice (Oryza sativa), consists of an asymmetrical pair of triple-helix bundles, connected by an inversion linker transmembrane helix (TM4) to create the translocation pathway [SWEET2b] (Mus musculus) PubMed

 15444.

Data show that mutant strains devoid of metalloproteinase mirolysin showed diminished survival: [mirolysin] (Mus musculus) PubMed

 15445.

lipoxin A4 and PAF are involved in E. coli or LPS-induced lung inflammation in CFTR-deficient mice.[PAF] (Mus musculus) PubMed

 15446.

The first structural characterization of the entire TpMan by small-angle X-ray scattering combined with the three-dimensional structures of the individual domains, is reported.[TpMan] (Mus musculus) PubMed

 15447.

Our results lead us to conclude that Bm-iAANAT2 is a new arylalkylamine N-acetyltransferase gene in the silkworm and is involved in the metabolism of the dopamine to avoid the generation of melanin. (Mus musculus) PubMed

 15448.

IL-37 requires IL-18Ralpha and SIGIRR/IL-1R8 to diminish allergic airway inflammation in mice (Mus musculus) PubMed

 15449.

This paper investigates drug binding pocket mutants of AcrB through the isolation and characterization of intragenic suppressor mutations that overcome the drug susceptibility phenotype of mutations affecting the drug binding pocket.[AcrB] (Mus musculus) PubMed

 15450.

results demonstrate that TbTim62, a unique mitochondrial protein in T. brucei, is required for the formation of a stable TbTim17 protein complex. (Mus musculus) PubMed

 15451.

The evidence presented here suggests functional differences between the PilY1 homologs, which may provide Xylella fastidiosa with an adaptive advantage in environments with high Ca concentrations, such as xylem sap.[PilY1] (Mus musculus) PubMed

 15452.

Structural analysis revealed how Hg2+ drives the formation of the metal binding site, and how Hg2+ regulates the conformational switching of MerR (MerR). (Mus musculus) PubMed

 15453.

Study highlights the potential role that IncX3 plasmids have played in the emergence and dissemination of blaNDM-4-like variants worldwide and emphasises the importance of resistance gene surveillance. (Mus musculus) PubMed

 15454.

Unlike the diminished ATPase activity of the inactive single-ring variant GroEL(SR)- GroES, all four single-ring variants hydrolyzed ATP at a level comparable to that of the double-ring GroEL-GroES. [GroEL, GroES] (Mus musculus) PubMed

 15455.

Plasmid-encoded tetracycline efflux pump protein alters bacterial stress responses and ecological fitness of Acinetobacter oleivorans [tetH] (Mus musculus) PubMed

 15456.

The absence of ccpA gene led to an increased expression of capsular polysaccharide. [CcpA] (Mus musculus) PubMed

 15457.

Using AlkD, crystallographically monitoring excision of an alkylpurine substrate as a function of time, and reconstructing the steps along the reaction coordinate through structures representing substrate, intermediate and product complexes [AlkD] (Mus musculus) PubMed

 15458.

The sequencing result showed that the length of aiiA(SS6) was 891 bp and the gene contained an Open Reading Frame encoding 297 amino acids.[aiiA] (Mus musculus) PubMed

 15459.

Rad2 is functional in the DNA repair of ultraviolet light damage. [Rad2] (Mus musculus) PubMed

 15460.

X-ray crystal structures of Fumitremorgin B endoperoxidase and the binary complexes it forms with either the co-substrate (alpha-ketoglutarate) or the substrate (fumitremorgin B) [FtmOx1] (Mus musculus) PubMed

 15461.

The present finding provides valuable insight into the probable link between covering and PAX6 expression of sea urchins (Mus musculus) PubMed

 15462.

Here, a CsoR-binding motif was found upstream of another copZ-like gene, copZ2, and the in vitro binding of the CsoR protein to its promoter was confirmed.[CsoR] (Mus musculus) PubMed

 15463.

High-resolution crystal structures of four mutants (T217V, T217A, M218L and G219V) of the ribosomal protein L1 in complex with a specific 80 nt fragment of 23S rRNA are eported here. [ribosomal protein L1] (Mus musculus) PubMed

 15464.

The study presents the structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A. [arylamine N-acetyltransferase] (Mus musculus) PubMed

 15465.

The crystal structures of 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase with several combinations of ligands, namely metal ion, citrate and products, were determined. [ 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase] (Mus musculus) PubMed

 15466.

GH76 alpha-mannanase homolog, BT2949 presents a classical (alpha/alpha)6-barrel structure comprising a large extended surface cleft common to other GH76 family members. [BT2949] (Mus musculus) PubMed

 15467.

The crystal structure of the SAV1646 protein from the pathogenic microorganism Staphylococcus aureus has been determined at 1.7 A resolution. [SAV1646 protein] (Mus musculus) PubMed

 15468.

The 1.71 A resolution crystal structure of L,D-carboxypeptidase DacB from S. pneumoniae TIGR4 is reported. [DacB] (Mus musculus) PubMed

 15469.

DNA cleavage is observed when the second manganese ion appears, suggesting that HindIII uses the two-metal-ion mechanism, or alternatively that its reactivity is enhanced by the binding of the second metal ion. [HindIII] (Mus musculus) PubMed

 15470.

The 1.24 A resolution crystal structure of the periplasmic i-type lysozyme inhibitor from Aeromonas hydrophila (PliI-Ah) in complex with the i-type lysozyme from Meretrix lusoria is reported. [PliI] (Mus musculus) PubMed

 15471.

The X-ray crystal structure of the nitrogenase MoFe protein from Clostridium pasteurianum is compared to the Azotobacter vinelandii MoFe protein crystal structure. [MoFe protein] (Mus musculus) PubMed

 15472.

The X-ray crystal structure of the nitrogenase MoFe protein from Clostridium pasteurianum (Cp1) has been determined at 1.08 A resolution by multiwavelength anomalous diffraction phasing. [MoFe protein] (Mus musculus) PubMed

 15473.

The higher CO2-reducing activity of Thiobacillus sp. NAD-dependent formate dehydrogenase is owing to its lower free-energy barrier to CO2 reduction than in the Candida boidinii enzyme. [NAD-dependent formate dehydrogenase] (Mus musculus) PubMed

 15474.

Whereas the NS5B Ser46D and Ser76D substitutions seemed to improve polymerase activity, the Ser96D mutation decreased colony formation efficiency. [NS5B] (Mus musculus) PubMed

 15475.

the ability to alleviate salt stress by OsGAP1 is dependent only on its ability to bind OsYchF1 and is independent of its phospholipid-binding activity (Mus musculus) PubMed

 15476.

Downregulation of MdPGRP-SC leads to the overexpression of the antimicrobial peptides, and is involved in the larvae-to-pupa transition of housefly.[PGRP-SC} (Mus musculus) PubMed

 15477.

first report to characterize a cholesterol oxidase from P. aeruginosa [cho] (Mus musculus) PubMed

 15478.

The mutant was less able to withstand acid and hyperosmotic conditions than wild-type strain but shown no significant difference with wild-type strain when challenged by elevated temperature and hypotonic conditions.[RegM] (Mus musculus) PubMed

 15479.

Here, the apicoplast dihydrolipoamide dehydrogenase was recombinantly expressed and its structure was characterized. [dihydrolipoamide dehydrogenase] (Mus musculus) PubMed

 15480.

This study is the first to identify functional class A scavenger receptors in rainbow trout epithelial cells, and contributes not only to a better understanding of modified LDL transport but also innate immunity in these animals.[scavenger receptor A] (Mus musculus) PubMed

 15481.

structure of a complete Na(+)-activated K(+) channel, chicken Slo2.2, in the Na(+)-free state, determined by cryo-electron [Slo2.2] microscopy at a nominal resolution of 4.5 angstroms (Mus musculus) PubMed

 15482.

AspC-mediated metabolism of aspartate coordinates the E. coli cell cycle. (Mus musculus) PubMed

 15483.

These data demonstrate that codon optimisation is crucial for Aeropyrum pernix pernisine overexpression in E. coli, and that the proposed catalytic Ser355 has an important role in pernisine activity (Mus musculus) PubMed

 15484.

High expression profile of OsMPK3/6, OsMKK4/5 and OsPIN 1b/9 and their marked transcript level modulation in response to both auxin and cytokinin was observed (Mus musculus) PubMed

 15485.

Results identified glpF involved in glycerol uptake being critical for L-form formation in Staphylococcus aureus. Also, glpF seems important for persistence to antibiotics.[glpF] (Mus musculus) PubMed

 15486.

Beta-Arrestin1 desensitizes steroid hormone 20-hydroxyecdysone signaling by interacting with G protein-coupled receptor. [Beta-Arrestin1] (Mus musculus) PubMed

 15487.

results showed the proteins regulated by CodY are involved in microbial metabolism; also found CodY is involved in sporulation, biosynthesis of poly-beta-hydroxybutyrate, growth, genetic competence and translation [CodY] (Mus musculus) PubMed

 15488.

results suggested that SpaA has an important role in the pathogenesis of E. rhusiopathiae infection and could be a target for vaccination against swine erysipelas [SpaA] (Mus musculus) PubMed

 15489.

The studies indicate that PD1063 plays a role in cell-cell aggregation in vitro but does not support a role for PD1063 in regulation of biofilm formation or as pathogenicity factor. [PD1063] (Mus musculus) PubMed

 15490.

PmNM is a new allele of Pm2, re-designated Pm2c, which confers resistance to powdery mildew (Mus musculus) PubMed

 15491.

The study proposes a model for RNase J catalysis (RNase J). (Mus musculus) PubMed

 15492.

The work provides the first biochemical evidence that both Cdc13 and RPA are capable of protecting telomeres from exonuclease-catalyzed resection. [Cdc13, RPA] (Mus musculus) PubMed

 15493.

A new stem rust resistance gene Sr49 was mapped to chromosome 5BL of wheat (Mus musculus) PubMed

 15494.

analysis of the thermodynamics and temperature dependence of the alkaline protease from Bacillus pumilus [DHAP] (Mus musculus) PubMed

 15495.

Kinetic analysis showed that ScIDH1 R148H and YlIDH R141H displayed 5.2-fold and 3.3-fold higher affinities, respectively, for alpha-KG than the HcIDH R132H mutant (Mus musculus) PubMed

 15496.

extents. Our findings suggested that pqqA and pqqB genes individually play important functions in PQQ biosynthesis and are required for antibacterial activity and phosphorous solubilization (Mus musculus) PubMed

 15497.

fbn-1 was required specifically within the epidermis and FBN-1 was expressed in epidermal cells and secreted to the apical surface as a putative component of the embryonic sheath.[FBN-1] (Mus musculus) PubMed

 15498.

Results showed that Cel12A is highly active on beta-glucan and thermally stable in acidic environment. [Cel12A] (Mus musculus) PubMed

 15499.

The structure of E. coli TcdA reveals a Rossmann fold with an extension at the C-terminus. This C-terminal fold provides a crucial interface for the tRNA substrate binding. [TcdA] (Mus musculus) PubMed

 15500.

Histidine kinase senses the temperature or mediates signal transduction of temperature effects. [Histidine kinase] (Mus musculus) PubMed

 15501.

The identification of this serine protease, named fusolisin, in three oral F. nucleatum sub-species, is reported.[Fusolisin] (Mus musculus) PubMed

 15502.

Yap1 and Sir2 discretely function in Hsf1 activation by oxidative stress and heat shock.[Yap1, Sir2, Hsf1] (Mus musculus) PubMed

 15503.

Microarray analysis and promoter-lacZ fusion studies showed that the transcriptional regulator NanR acts as a transcriptional activator of nan operon I and the nanA gene in the presence of sialic acid.[NanA] (Mus musculus) PubMed

 15504.

Slx9 functions as a scaffold to optimally present RanGTP and the NES to Crm1, therefore, triggering 40S pre-ribosome export.[Crm1] (Mus musculus) PubMed

 15505.

The folding of Halo-RNase H1 is induced by binding of divalent metal ion to the quad-aspartate site in a low-salt condition. [RNase H1] (Mus musculus) PubMed

 15506.

PssP2 is a polysaccharide co-polymerase involved in exopolysaccharide chain-length determination in Rhizobium leguminosarum. [PssP2] (Mus musculus) PubMed

 15507.

we report the identification and characterization of a novel membrane-embedded retropepsin-like homologue, highly conserved in 55 Rickettsia genomes (Mus musculus) PubMed

 15508.

The study characterizes the denaturant-dependent structure of apoflavodoxin's off-pathway Molten Globule. [flavodoxin] (Mus musculus) PubMed

 15509.

TgHMGB1a is indeed a nuclear protein that maintains HMG box architectural functions and is a potential proinflammatory factor during the T.gondii infection. [TgHMGB1a] (Mus musculus) PubMed

 15510.

we show that the m166 open reading frame (of mouse cytomegalovirus is strictly required to inhibit expression of TRAIL-DR in infected cells (Mus musculus) PubMed

 15511.

The rate of Fis dissociation from DNA is strongly dependent on the solution concentration of DNA. (Mus musculus) PubMed

 15512.

Our observations suggest that the interaction between Borrelia and Ixofin3D facilitates spirochete congregation to the gut during transmission, and provides a "molecular exit" direction for spirochete egress from the gut. (Mus musculus) PubMed

 15513.

An essential role of the Ste12 transcriptional regulator in mediating outcomes of the Tmk1 MAPK pathway such as regulation of the mycoparasitic activity, hyphal fusion and carbon source-dependent vegetative growth is suggested.[Ste12, Tmk1] (Mus musculus) PubMed

 15514.

These data uncover a previously unidentified mechanism that links ApoE4-induced phospholipid changes to the pathogenic nature of ApoE4 in Alzheimer's disease.[ApoE4] (Mus musculus) PubMed

 15515.

YehZYXW is a betaine transporter that shares substrate specificity, but not an osmoregulatory function, with homologues like E. coli ProU. [YehZYXW] (Mus musculus) PubMed

 15516.

Xa40 confers resistance to bacterial blight [Xa40] (Mus musculus) PubMed

 15517.

Suggest Candida albicans Sey1p causes homotypic fusion of endoplasmic reticulum membranes. (Mus musculus) PubMed

 15518.

Klpdr16Delta mutant is hyperpolarized and its fluidity is lower than that of the parental strain. [PDR16] (Mus musculus) PubMed

 15519.

the molecular basis for the expanded substrate specificity of the mutant meso-diaminopimelate dehydrogenases [meso-diaminopimelate dehydrogenase] (Mus musculus) PubMed

 15520.

Site-directed mutagenesis and kinetic experiments show that BsaWI is active as a tetramer and requires two target sites for optimal activity (BsaWI). (Mus musculus) PubMed

 15521.

on the other hand, activation of PMCA4 was found to enhance the parasite burden. Our findings also highlighted the importance of Ca2+ in the modulation of cytokine balance during leishmaniasis (Mus musculus) PubMed

 15522.

The data presented in this study indicate that indole signaling and the alternative sigma factor RpoS have a significant impact on the virulence of V. anguillarum.[RpoS] (Mus musculus) PubMed

 15523.

study demonstrates that rVvpM-induced cell death occurs via multiple pathways, including necroptosis and autophagy in addition to apoptosis; the multifarious action of VvpM might be one of the factors responsible for V. vulnificus pathogenesis [VvpM] (Mus musculus) PubMed

 15524.

The study concluded that Bmovo-1 was involved in protein synthesis, contributing to the development of ovaries and oviposition number in silkworms. [Bmovo-1] (Mus musculus) PubMed

 15525.

The region of rice 13 kDa prolamin essential for the formation of endoplasmic reticulum -derived protein bodies has been identified. [13a prolamin] (Mus musculus) PubMed

 15526.

functional regions in the Msb2 structure contribute to various cellular processes, including hypha formation, activation of the MAP kinase Cek1, basal antifungal resistance, and regulation of the transcriptome [Msb2] (Mus musculus) PubMed

 15527.

Results of the kinetic parameters of CfcI showed that this CBM18, a Carbohydrate Binding Module of family 18 is functionally involved in the chitinase catalytic activity. [CfcI] (Mus musculus) PubMed

 15528.

membrane-active substances other than bile acids also affect the activity of BASIC.[BASIC] (Mus musculus) PubMed

 15529.

Gene mdpC of Methylibium petroleiphilum strain PM1 is involved in the induction of both mdpA and mdpJ in response to methyl tert-butyl ether (MTBE) and tert-butyl alcohol (TBA) exposure [mdpC] (Mus musculus) PubMed

 15530.

X-ray crystallographic structure of the catalytic domain of Ala-tRNA(Ala)-dependent alanyl-phosphatidylglycerol synthase. A-PGS (Mus musculus) PubMed

 15531.

Evidence suggests that intragenic recombination is an important strategy in the evolutionary adaptive process playing an active role on sidJ genetic plasticity (Mus musculus) PubMed

 15532.

X-ray crystallographic structure of the lysyl-phosphatidylglycerol-specific domain of Lys-tRNA(Lys)-dependent lysyl-phosphatidylglycerol synthase from Bacillus licheniformis in complex with the substrate analog L-lysine amide. L-PGS (Mus musculus) PubMed

 15533.

By regulating the fate of HXL1 mRNA, Puf4 is able to modulate unfolded protein response kinetics [Puf4] (Mus musculus) PubMed

 15534.

The introduction of a self-replicating plasmid expressing Trt1 into the mutant strain restored growth proficiency and replicative potential. (Mus musculus) PubMed

 15535.

avidity for the substrate plays an important role in imparting specificity on the PPP1R15B-PP1G-actin ternary complex.[G-actin] (Mus musculus) PubMed

 15536.

comp-1 functions in sperm to modulate their migration through and localization within the reproductive tract.[COMP-1] (Mus musculus) PubMed

 15537.

The I559P change completely eliminated the ability of the HIV-1BG505 Env to mediate cell-cell fusion and virus entry, and abolished the capacity of the SOS Env to support virus infection in the presence of a reducing agent. (Mus musculus) PubMed

 15538.

The ABC transporter encoded by abcEDCBA acts at a post-transcriptional level to promote the optimal expression of the B. ovis type 4 secretion system within infected host cells. [abcEDCBA] (Mus musculus) PubMed

 15539.

Thus, PbgA forms a complex that may bridge the envelope for regulated cardiolipin delivery.[PbgA] (Mus musculus) PubMed

 15540.

finding demonstrates that the extension region in PrhG is responsible for the functional difference between HrpG and PrhG, which may block the binding of PrhG to target promoters and result in impaired activation of hrp expression by PrhG and reduced virulence of R. solanacearum [PrhG] (Mus musculus) PubMed

 15541.

A mis-annotation of the Rre1 protein has been identified and the correct version has been functionally characterized in vitro.[Rre1] (Mus musculus) PubMed

 15542.

this study isolated a partial sequence of the wheat small subunit of RuBisCO (TarbcS) promoter.[TarbcS] (Mus musculus) PubMed

 15543.

This finding highlights a novel level of complexity of the regulatory network in which the concerted action of transcriptional regulators and multiple non-coding RNAs under control of CRP adjusts the control of Yersinia fitness and virulence. (Mus musculus) PubMed

 15544.

MetZ appears to be a second transcription factor involved in regulation of sulfur metabolism genes. (Mus musculus) PubMed

 15545.

The results reveal that OsMATE1 and OsMATE2 regulate plant growth and development as well as negatively affect disease resistance. [MATE1] and [MATE2] (Mus musculus) PubMed

 15546.

results suggest that H. pylori peptidyl-prolyl cis-trans isomerase has the potential to activate mitogenic signaling pathway and to promote transformation of gastric epithelial cells [peptidyl-prolyl cis-trans isomerase] (Mus musculus) PubMed

 15547.

the mutated ASL2 gene was isolated and found to encode the chloroplast 50S ribosome protein L21 (RPL21c), a component of the chloroplast ribosome large subunit, which was localised in chloroplasts. [ASL2] (Mus musculus) PubMed

 15548.

These results suggest that many stressors may cause both oxidative stress and direct DNA damage, and that DNA-binding protein from starved cells (Dps) protects bacterial cells.[Dps] (Mus musculus) PubMed

 15549.

Grx4 independently governs the Php4 and Fep1 repressors through metal transfer. total or partial disassembly of the Grx4-Fra2 cluster actively participates in iron-containing Fep1 activation (Mus musculus) PubMed

 15550.

The host cell motility inhibitory action of Yersinia enterocolitica YspI comes about through its specific interaction with focal adhesion kinase, FAK, which is a fulcrum of focal adhesion complexes for controlling cellular motility.[YspI] (Mus musculus) PubMed

 15551.

we localized the sup9 suppressor gene physically to the spctrnaser.11 locus and confirmed that the mechanism of suppression involves mutation of the anticodon of a serine tRNA (Mus musculus) PubMed

 15552.

Thus, vaccinia virus decapping via D9 and D10 decapping enzymes, in addition to targeting mRNAs for degradation, prevents dsRNA accumulation and anti-viral responses.[D9, D10] (Mus musculus) PubMed

 15553.

Our results suggest that miR-H2 downregulates ICP0 and this moderates both HSV-1 neurovirulence and reactivation (Mus musculus) PubMed

 15554.

Analysis of the amplification process during the adaptive evolution revealed formation of a XylA-carrying eccDNA, pXI2-6, followed by chromosomal integration in tandem arrays over the course of the evolutionary adaptation. (Mus musculus) PubMed

 15555.

The critical mutation in dim-3 results in a substitution in an ARM repeat of NUP-6 and causes a substantial loss of H3K9me3 and DNA methylation. (Mus musculus) PubMed

 15556.

These findings call for a substantially revised interpretation of the literature concerning H-NS and flagellar motility and highlight the importance of H-NS in diverse regulatory processes involved in the motile-sessile transition.[H-NS] (Mus musculus) PubMed

 15557.

The host cell type may influence the protein transport mechanisms used by blood-stage parasites and that in reticulocytes, exported protein 2 (Exp2) may function at multiple points in the export-transport pathway. [Exp2] (Mus musculus) PubMed

 15558.

We believe all of these regulatory arms converge to increase transcription of pho1 (+) and some of the regulation acts through pho7 (+). (Mus musculus) PubMed

 15559.

AgnB is a membrane-anchored extracellular alpha-N-acetylglucosaminidase enzyme consisting of a GH89 domain and four carbohydrate-binding module (CBM) 32 domains.[AgnB] (Mus musculus) PubMed

 15560.

MrSkn7 is required not only for fungal conidiation, cell wall integrity maintenance, appressorium differentiation and virulence but also for cell autolysis [Skn7] (Mus musculus) PubMed

 15561.

Data show that the NADH-dependent reduced ferredoxin:NADP oxidoreductase (NfnAB) complex structure determines the positions of the prosthetic groups and the substrates: [NfnA and NfnB] (Mus musculus) PubMed

 15562.

sreA is a critical transcription factor gene required for prochloraz resistance and full virulence in P. digitatum. [sreA] (Mus musculus) PubMed

 15563.

All these results suggest that Entamoeba histolytica contains as a minimum one structural and functional protein ortholog to PRMT1, enzyme that potentially dimethylates H4R8.[PRMT1] (Mus musculus) PubMed

 15564.

study found Asp142, Asp171 and Glu31, located on the hydrophilic molecular surface of CutL1, and His32 and Lys34, located in the N-terminus of RolA, play crucial roles in the RolA-CutL1 interaction via ionic interactions[ RolA, CutL1] (Mus musculus) PubMed

 15565.

Analysis of the Y. pestis TesB thioesterase activity revealed a strong preference for octanoyl-CoA and this is supported by structural analysis of the active site. [TesB] (Mus musculus) PubMed

 15566.

The 2.45 A resolution crystal structure of the McyG A-PCP didomain complexed with the catalytic intermediate L-phenylalanyl-adenylate (L-Phe-AMP) is reported. [McyG] (Mus musculus) PubMed

 15567.

Corynebacterium glutamicum Nal is more related to dihydrodipicolinate synthase (DHDPS) by phylogenetic analysis. [NAL] (Mus musculus) PubMed

 15568.

Results showed that Cpcul1-double strand RNA caused dose-dependent suppression of Cpcul1 expression and caused stunting of larval growth but did not affect viability. [cul1] (Mus musculus) PubMed

 15569.

Alr4641 can protect Anabaena from oxidative stress.[Alr4641] (Mus musculus) PubMed

 15570.

AS1 is apparently coupled with the primary assimilation of ammonium in rice roots.[AS1] (Mus musculus) PubMed

 15571.

LHCSR1 localizes in the chloroplast thylakoid membranes, and is correctly folded with chlorophyll a and xanthophylls but without chlorophyll b, an essential chromophore for plants and algal LHC proteins [LHCSR1] (Mus musculus) PubMed

 15572.

Four new crystal structures of the ATPase domain of the GyrB subunit of Escherichia coli DNA gyrase have been determined. [GyrB] (Mus musculus) PubMed

 15573.

Here a near-atomic resolution crystal structure of a PWI-like domain that resides in the N-terminal region of Chaetomium thermophilum Brr2 is presented. [Brr2] (Mus musculus) PubMed

 15574.

The crystal structure of struthiocalcin-1 (SCA-1) is reported in two different crystal forms. [struthiocalcin-1] (Mus musculus) PubMed

 15575.

WtsE is a pathogenicity and virulence factor in maize.[WtsE] (Mus musculus) PubMed

 15576.

The crystal structure of MoxT. [MoxT] (Mus musculus) PubMed

 15577.

D. discoideum also contains lpten, a newly discovered homolog of ptenA. Overexpressing lpten completely rescues all developmental and behavioral defects of the D. discoideum mutant ptenA-. lpten. (Mus musculus) PubMed

 15578.

A combination of the crystal structure and biochemical functional assays suggests that MtrF is an antibiotic efflux pump mediating bacterial resistance to sulfonamide antimetabolite drugs (Mus musculus) PubMed

 15579.

Identification of the VERNALIZATION 4 gene reveals the origin of spring growth habit in ancient wheats from South Asia. (Mus musculus) PubMed

 15580.

although both systems may require free histidine, SaNikA and SaCntA use different strategies to import nickel [NikA, CntA] (Mus musculus) PubMed

 15581.

Our studies suggest M. smegmatis Deltaarr(ADP ribosyltransferase ) strain as an ideal model system in drug testing and mutation spectrum determination in DNA repair studies. (Mus musculus) PubMed

 15582.

Serine 26 in the PomB subunit of the flagellar motor is essential for hypermotility of Vibrio cholera. [PomB] (Mus musculus) PubMed

 15583.

A hexR mutant of strain PG4180 was significantly growth-impaired when incubated with sucrose or glucose as sole carbon source, but exhibited wild type growth when arabinose was provided.[HexR] (Mus musculus) PubMed

 15584.

The authors show that VieB binds to VieS and inhibits its autophosphorylation and phosphotransfer activity thus preventing phosphorylation of VieA.[VieA, VieB, VieC] (Mus musculus) PubMed

 15585.

This provides genetic evidence that CtHtrA is critical for the Chlamydia trachomatis developmental cycle.[HtrA] (Mus musculus) PubMed

 15586.

VP2 can induce apoptosis in the host cell. [VP2] (Mus musculus) PubMed

 15587.

The rpoE2 and RpoE2-dependent pgpD gene encoding a periplasmic glutathione peroxidase are involved in oxidative stress responses.[rpoE2, pgpD] (Mus musculus) PubMed

 15588.

LuxI and AinS are the autoinducer synthases responsible for the eight N-acyl-homoserine lactones in Aliivibrio salmonicida.[LuxI and AinS] (Mus musculus) PubMed

 15589.

APLP1 is able to induce cell death, and FoxO is a crucial downstream mediator of APLP1's activity.[APLP1] (Mus musculus) PubMed

 15590.

Further experiments designed to raise the level of acetyl phosphate within the cell suggest that DegU can be phosphorylated by acetyl phosphate in the absence of degS.[DegU] (Mus musculus) PubMed

 15591.

Studies show that OipA is an outer membrane inflammatory protein that closely correlates with H. pylori-related diseases, and may be used for clinical diagnosis and prediction of disease outcome. [OipA] , [review] (Mus musculus) PubMed

 15592.

Taken together, when S-adenosylmethionine is limiting, HemN is apparently nonfunctional, and heme synthesis is continued by HemF.[HemN, HemF] (Mus musculus) PubMed

 15593.

A protein-protein docking modeling of Synechocystis glutamine synthetase (GS) in complex with IF7 supports the role of the identified core for GS/IF interaction.[GS] (Mus musculus) PubMed

 15594.

These results suggest a mechanism involving hypochlorite scavenging by sacrificial oxidation of the MrpX in the periplasm. Reduced MrpX is regenerated by the YedY methionine sulfoxide reductase activity.[MrpX, YedY] (Mus musculus) PubMed

 15595.

directly activates photosynthesis genes, cascades of transcription factors and other downstream genes involved in photosynthetic carbon metabolism and yield stability under drought and high-temperature environmental stress conditions [HYR/Os03g02650) (Mus musculus) PubMed

 15596.

Antp and POU-M2 coordinate the transcription of the silkworm Phm gene directly, indicating new roles for homeodomain proteins in regulating insect ecdysteroidogenesis [Phantom - Phm] (Mus musculus) PubMed

 15597.

study reveals that NcsA is essential for growth at high temperature, required for formation of thiolated tRNA(Lys)UUU (Mus musculus) PubMed

 15598.

Crystal structure of the diheme cytochrome c from Shewanella baltica (OS155). (Sb-DHC) (Mus musculus) PubMed

 15599.

The authors show that in addition to phosphorylation by CheA3, the phosphorylation state of CheS3 is also regulated by the cellular energy level as quantified by the molar ratio of ATP/(ATP + ADP).[CheS3] (Mus musculus) PubMed

 15600.

TaR1 is an important component for the pathogen life cycle in wheat that promotes successful colonization by Septoria. [TaR1] (Mus musculus) PubMed

 15601.

a basal body protein SPBB1 as a TbPLK substrate[SPBB1][PLK] (Mus musculus) PubMed

 15602.

Penicillin V acylase contains a hydrophobicpocket involved in catalytic activity, including Serbeta1, Hisbeta23, Valbeta70, and Asnbeta272. [penicillin V acylase] (Mus musculus) PubMed

 15603.

function of Csd6 in regulating the helical cell shape and motility of H. pylori [Csd6] (Mus musculus) PubMed

 15604.

a role for DNA distortion in Rx1 immune signaling (Mus musculus) PubMed

 15605.

The study investigated the conformational changes of the ABC transporter McjD following MccJ25 translocation and release to the extracellular side. [McjD] (Mus musculus) PubMed

 15606.

These results suggest that Staphylococcus aureus nitric oxide reductase (NOR) contributes to nitric oxide-dependent respiration during nitrosative stress, possibly conferring an advantage to nor+ strains in vivo.[NOR] (Mus musculus) PubMed

 15607.

The L25K and L125K variants of staphylococcal nuclease (SNase) were used to characterize the diverse types of structural reorganization that can be promoted by the ionization of buried groups. [staphylococcal nuclease] (Mus musculus) PubMed

 15608.

Bilin protonation is not a key parameter for controlling the energies of the electronic transitions in AnPixJg2. [AnPixJg2] (Mus musculus) PubMed

 15609.

FtsZ from Streptococcus pneumoniae Exhibits a GTPase Activity Delay [FtsZ] (Mus musculus) PubMed

 15610.

MavN is a vacuole-associated protein with a critical role in iron acquisition during intracellular growth [MavN] (Mus musculus) PubMed

 15611.

Migration inhibition of dHL-60 cells in an under agarose assay was dependent on the Helicobacter pylori cag pathogenicity island, on its effector protein CagA, and on the outer membrane protein HopQ.[CagA, HopQ] (Mus musculus) PubMed

 15612.

Manganese superoxide dismutase from human pathogen Clostridium difficile has been cloned and characterized. [Mn-SOD] (Mus musculus) PubMed

 15613.

ICP8 binding to G3BP also inhibits SG formation, which is a novel function of HSV ICP8. (Mus musculus) PubMed

 15614.

The data characterizes 2 Dicer-like proteins in Wheat: DCL4, a 21 nt processing activity and DCL3, a 24 nt one. DCL4 is a 950 kDa protein and highly instable for purification. On the contrary, DCL3 is smaller and relatively stable.[DCL3] and [DCL4]. (Mus musculus) PubMed

 15615.

CrdR is a positive transcriptional regulator of the crd operon for promoting curdlan biosynthesis in Agrobacterium sp. ATCC31749 strain. [CrdR] (Mus musculus) PubMed

 15616.

CprRS is the first C. jejuni regulatory system shown to control genes related to the cell envelope, the first line of interaction between pathogen and changing environments.[CprR, CprS] (Mus musculus) PubMed

 15617.

LACK promotes Leishmania adaptation to the mammalian host environment by sustaining LmCOX subunit IV expression and hence energy metabolism in response to stress stimuli such as heat. [LACK] (Mus musculus) PubMed

 15618.

EP3 plays a role in regulating stomatal guard cell development. [EP3] (Mus musculus) PubMed

 15619.

findings show PcaY encodes the methyl-accepting chemotaxis protein required for metabolism-independent chemotaxis to vanillate, vanillin, 4-hydroxybenzoate, benzoate, protocatechuate, quinate, shikimate, as well as 10 substituted benzoates that do not serve as growth substrates [pcaY] (Mus musculus) PubMed

 15620.

Genetic complementation restored disruptions in motility and the YplA export phenotype (Yex), which confirmed this mutation disrupted CsrA function.[CsrA] (Mus musculus) PubMed

 15621.

These results suggest that the ClpAP complex regulates massetolide biosynthesis via the pathway-specific, LuxR-type regulator MassAR, the heat shock proteins DnaK and DnaJ, and proteins of the tricarboxylic acid cycle. (Mus musculus) PubMed

 15622.

TaNAC-S is a negative regulator of leaf senescence, and that delayed leaf senescence may lead not only to increased grain yields but also to increased grain protein concentrations. [TaNAC-S] (Mus musculus) PubMed

 15623.

OsARF19 works in controlling leaf angle trough OsGH3-5 and OsBRI1. [OsARF19, OsBRI1, OsGH3-5] (Mus musculus) PubMed

 15624.

The Wze tyrosine kinase protein of Lactobacillus rhamnosus thus carries out tyrosine phosphorylation of Wzd in addition to auto- and trans- phosphorylation of the kinase itself.[Wzd, Wze] (Mus musculus) PubMed

 15625.

This study provides the evidence that MoMyb1 is a key regulator involved in conidiogenesis, stress response, cell wall integrity and pathogenesis on rice roots in the filamentous phytopathogen Magnaporthe oryzae.[Myb1] (Mus musculus) PubMed

 15626.

WRKY45-2 transcriptionally activates WRKY13, whose encoding protein in turn transcriptionally suppresses WRKY42 to regulate rice resistance to M. oryzae.[WRKY42-5, WRKY13, WRKY42] (Mus musculus) PubMed

 15627.

these results indicated that insulin pre-administration effectively alleviated liver oxidative injury but also deteriorated hepatic steatosis through SRBEP-1c activation in mice exposed to ethanol.[SRBEP-1c] (Mus musculus) PubMed

 15628.

the vestigial-like family member 3 gene (VGLL3) exhibits sex-dependent dominance in salmon, promoting earlier and later maturation in males and females, respectively [VGLL3] (Mus musculus) PubMed

 15629.

Some Laz protein is exposed on the outer membrane surface of Neisseria meningitidis as the alphaLaz antibodies can increase killing by complement in a capsule deficient Neisseria meningitidis strain, in a dose-dependent fashion.[Laz] (Mus musculus) PubMed

 15630.

data clearly indicates that PcAtfA governs spore germination[PcAtfA] (Mus musculus) PubMed

 15631.

SipA functions by binding a key component at the bacterial cell surface, in a conformation that facilitates pilus assembly. (Mus musculus) PubMed

 15632.

CslB of Neisseria meningitidis serogroup L is a capsule polymerase that catalyzes the synthesis of a complex trimeric repeating unit comprising glycosidic and phosphodiester linkages [CslB] (Mus musculus) PubMed

 15633.

The alpha-hemolysin protein binds to the membrane as a monomer, assembles to form a heptamer, and forms a nanopore. [alpha-hemolysin] (Mus musculus) PubMed

 15634.

Cyclic diGMP regulates sortase substrate CD2831 and CD3246 production through ZmpI protease mediated cleavage [CD2831, CD3246, ZmpI] (Mus musculus) PubMed

 15635.

MalR activation of malleilactone synthesis genes is not responsive to acyl-homoserine lactone. [MalR] (Mus musculus) PubMed

 15636.

substrate specificity of rice (Oryza sativa) phytaspase [phytaspase] (Mus musculus) PubMed

 15637.

Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapse. [RTS1] (Mus musculus) PubMed

 15638.

In Natrinema sp. J7-2, SptA is secreted primarily during stationary phase, and the intracellular accumulation of mature enzyme occurs during the stationary and death phases.[SptA] (Mus musculus) PubMed

 15639.

TkmA contributes to biofilm formation largely independently of the cognate kinase, PtkA. [TkmA, PtkA] (Mus musculus) PubMed

 15640.

PnpCD is a two-subunit hydroquinone 1,2-dioxygenase that is a member of a novel structural class of Fe2+-dependent dioxygenases [PnpCD] (Mus musculus) PubMed

 15641.

Results show that bla-A was expressed differentially among strains of different biovars and presented structural variability conferring differential sensitivity to beta-lactams and beta-lactamase inhibitors. [blaA] (Mus musculus) PubMed

 15642.

structure and catalytic activity of HisA [HisA] (Mus musculus) PubMed

 15643.

NatA-mediated protein modification as an early regulatory step crucial for efficient mitophagy [NatA] (Mus musculus) PubMed

 15644.

two novel nucleotide binding domains in lpg1496 [lpg1496] (Mus musculus) PubMed

 15645.

The crystal structures of CODH in complex with CO2 and the isoelectronic inhibitor NCO(-) are reported at true atomic resolution (dmin </=1.1 A). Like CO2, NCO(-) is a mu2,eta(2) ligand of the cluster and acts as a mechanism-based inhibitor. [CODH] (Mus musculus) PubMed

 15646.

OsABA8ox3 gene plays an important role in controlling ABA level and drought stress resistance in rice (Mus musculus) PubMed

 15647.

We find that microtubules promote the formation of Hsp104-positive aggregates, which coalesce into discrete subcellular structures in a process dependent on the microtubule-based motor cytoplasmic dynein (Mus musculus) PubMed

 15648.

work identifies tesS as the gene responsible for the difference in exogenous fatty acid growth requirement of the DeltaplsX strains of S. aureus and S. pneumonia [tesS] (Mus musculus) PubMed

 15649.

Determined is the X-ray crystal structure of the cytoplasmic anti-sigma domain (ASD) of Pseudomonas Sigma Regulator, PupR to 2.0 A. [PupR] (Mus musculus) PubMed

 15650.

Data show that contact-dependent growth inhibition (CDI+) bacteria export filamentous CdiA effector membrane proteins, and upon binding its receptor, CdiA delivers a toxin derived from its C-terminal region: [CdiA] (Mus musculus) PubMed

 15651.

UdgX is a novel Uracil DNA glycosylase that specifically recognizes uracil in DNA, forms a tight complex that is stable and shows no detectable uracil excision (UdgX). (Mus musculus) PubMed

 15652.

BiP/GRP78 played critical roles and works upstream of JNK-Bim in response to the ARV S1133-mediated apoptosis process.[Bim] (Mus musculus) PubMed

 15653.

Findings support a mechanism in which ToxR recruits TcpP to the toxT promoter for transcription activation.[TcpP, toxT, ToxR] (Mus musculus) PubMed

 15654.

These results reveal an unprecedented mechanism for competence regulation and stress tolerance by a gene product encoded within the comX gene that appears unique to Streptococcus mutans.[ComX] (Mus musculus) PubMed

 15655.

Substrate binding modes in a bacterial catalase from Bacillus pumilus. [Catalase] (Mus musculus) PubMed

 15656.

Ion channel gating mechanism of a bacterial, cyclic AMP activated, potassium channel. [SthK] (Mus musculus) PubMed

 15657.

In silico secondary structure analysis of the full mRNA operons of stx2a and stx2c suggest that transcript structural differences may also contribute to a relative increase of Stx2a over Stx2c. In consequence, toxin expression may be under both transcriptional and post-transcriptional control. [Stx2a, Stx2c Escherichia coli (STEC) O157:H- strain E32511] (Mus musculus) PubMed

 15658.

Over the range of adhesion forces of between 1 and 5 nN, icaA gene expression decreased , while for cidA gene expression, no influence of adhesion forces was found.[icaA and cidA] (Mus musculus) PubMed

 15659.

Study shows that an organism can possess active enzymes that catalyze both of the 2 known pathways that form dUMP from cytosine deoxyribonucleotides. B. halodurans can generate dUMP from dUTP directly or from either dCTP or dCMP; regulation of the 2 genes comEB and dcdB responds similarly to the nucleosides thymidine and deoxycytidine in the medium.[comEB, dcdB] (Mus musculus) PubMed

 15660.

Disruption of zwf-1 gene has a very clear stimulatory effect on alginate synthesis. [zwf-1] (Mus musculus) PubMed

 15661.

Hap does not contribute to bacterial biofilm growth, and that its absence partially restores the deficiency in lung infection observed for the DeltaompP5 mutant.[P5, Hap] (Mus musculus) PubMed

 15662.

Figla might play an essential role in the ovarian development by antagonizing spermatogenesis.[Figla] (Mus musculus) PubMed

 15663.

Data indicate that the compound genotype of homozygous C1 (+) Patr-B combined with either Pt-KIR3DS2 or Pt-KIR2DL9 is more strongly associated with HCV infection disease progression than either factor alone: [Pt-KIR3DS2 and Pt-KIR2DL9] (Mus musculus) PubMed

 15664.

Observed that the expression of a GATA2/3 homolog (cgi-gata2/3) was clearly restricted to the edge of the shell field in early larval stages (trochophore and D-veliger). This expression pattern supports the notion that cgi-gata2/3 gene plays conserved roles in bilaterian ectodermal development. [GATA2/3] (Mus musculus) PubMed

 15665.

Magic-angle spinning solid-state NMR spectroscopy has been applied to study the dynamics of CBM3b-Cbh9A from Clostridium thermocellum (ctCBM3b), a cellulose binding module protein. [CBM3b] (Mus musculus) PubMed

 15666.

overexpression of MdJAZ2 inhibits the recruitment of MdbHLH3 to the promoters of MdMYB9 and MdMYB11.[MdMYB9, MdMYB11] (Mus musculus) PubMed

 15667.

results suggest that BBA33 interacts with collagenous structures and may function as an adhesin in a process that is required to prevent bacterial clearance [BBA33] (Mus musculus) PubMed

 15668.

Therefore, SepJ can form multimers, and in Anabaena, the divisome has a role beyond cell division, localizing a septal protein essential for multicellularity.[SepJ, FtsQ] (Mus musculus) PubMed

 15669.

Collectively, these data reveal that LiZIP3 enables Leishmania infantum to acquire zinc in a highly regulated manner, hence contributing to zinc homeostasis.[LiZIP3] (Mus musculus) PubMed

 15670.

The scheme presented here is shown to shed light on the origin of catalysis in wild-type haloalkane dehalogenase (wt-DhlA) and its mutants. [haloalkane dehalogenase] (Mus musculus) PubMed

 15671.

NirC from the enteropathogen Salmonella typhimurium has been studied by X-ray crystallography, proton uptake assays, and different electrophysiological techniques. [NirC] (Mus musculus) PubMed

 15672.

characterization of a novel PQQ-dependent quinohemoprotein pyranose dehydrogenase from Coprinopsis cinerea [PDH] (Mus musculus) PubMed

 15673.

The study reports three P. aeruginosa LpxA crystal structures: apo protein, substrate complex with UDP-GlcNAc, and product complex with UDP-3-O-(R-3-hydroxydecanoyl)-GlcNAc. [LpxA] (Mus musculus) PubMed

 15674.

Phytoplasma variable membrane protein VmpA is responsible for insect vector transmission and contact with host Vitis phloem. [VmpA] (Mus musculus) PubMed

 15675.

The structures revealed that Vis toxin represents a new subgroup within the mono-ADP-ribosyltransferase toxin family. [ADP-ribosyltransferase] (Mus musculus) PubMed

 15676.

analysis of a novel splice variant of the Decapentaplegic (dpp) gene in B. mandarina [dpp] (Mus musculus) PubMed

 15677.

Data shows that ReBDH protein, a (2R,3R)-2,3-butanediol dehydrogenase is a monomeric structure, active within broad ranges of pH and temperature and likely associated with the formation of (2R,3R)-2,3-butanediol rather than its oxidation. [ReBDH ] (Mus musculus) PubMed

 15678.

The interaction between HPr and PykA was dependent on the presence of inorganic phosphate, and only dephosphorylated HPr interacted with PykA. [pykA, HPr] (Mus musculus) PubMed

 15679.

Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology [GlnR][CodY] (Mus musculus) PubMed

 15680.

IcsA polarity and diffusion of IcsA in the outer membrane is not affected by LPS O-antigen presence; IcsA is affected by symmetrical masking; O-antigen chain lengths are symmetrically distributed; changes in O-antigen synthesis can deregulate IcsA levels effecting polarity [IcsA] (Mus musculus) PubMed

 15681.

FasX enhances virulence and inhibits pilus expression.[FasX] (Mus musculus) PubMed

 15682.

The temporal patterns of genes involved in the ascorbate-glutathione cycle during leaf senescence were investigated using two rice genotypes, namely, the early senescence leaf (esl) mutant and its wild type.[esl] (Mus musculus) PubMed

 15683.

This work provides new insight into the mechanism by which OsMADS32 regulates rice lodicule and stamen identity, by interaction with two PI-like proteins via its K domain.[OsMADS32] (Mus musculus) PubMed

 15684.

Homology modeling and molecular dynamic studies show three-dimensional structure of the protease 3CLpro and supports further experimental validation of the inhibitory effects of ML188. [3CLpro] (Mus musculus) PubMed

 15685.

Site-directed mutagenesis was used to demonstrate that the shallot virus X TGB3 could be translated on a bicistronic mRNA template via a leaky scanning mechanism.[TGB3] (Mus musculus) PubMed

 15686.

The results indicated that OsmY may function to resist the stress and be favorable for Salmonella's replication in the Salmonella-containing vesicles of macrophage.[OsmY] (Mus musculus) PubMed

 15687.

These studies add a new member of plant associated bacteria LuxR solos and also provide new insights into the role of the LuxR solo in the virulence of Xanthomonas species.[XocR] (Mus musculus) PubMed

 15688.

OsHBP1b contributes to abiotic stress tolerance through multiple physiological pathways.[OsHBP1b] (Mus musculus) PubMed

 15689.

The study reports the strength of the P. aeruginosa BfrB:Bfd association using surface plasmon resonance and isothermal titration calorimetry as well as determines the binding energy hot spots at the protein-protein interaction interface. (Mus musculus) PubMed

 15690.

KAP8 is required for nuclear import of the cellulase transcriptional regulator XYR1. [KAP8, XYR1] (Mus musculus) PubMed

 15691.

These results demonstrate that Stenotrophomonas maltophilia senses acyl homoserine lactones produced by neighboring bacteria through the LuxR solo SmoR, regulating population behaviors such as swarming motility.[SmoR] (Mus musculus) PubMed

 15692.

The guinea-pig expresses functional CYP2C and P-gp, thus suggesting its usefulness for further validating data obtained with other animal models in drug biotransformation/transport studies [CYP2C] (Mus musculus) PubMed

 15693.

Rot repressed secreted protease levels in order to build a biofilm. [Rot] (Mus musculus) PubMed

 15694.

PscI form the type III secretion system inner rod, possesses intrinsic properties to polymerize into flexible and regularly twisted fibrils. [PscI] (Mus musculus) PubMed

 15695.

Results show that UreI transporter adopts different conformations at different pH especially in the periplasmic regions, were two loops with high flexibility experienced different orientations discriminating between an open and closed conformation. [UreI] (Mus musculus) PubMed

 15696.

MBP stimulation upregulated the expression of TLR2 and TLR4 on RAW264.7 cells.[Maltose binding protein] (Mus musculus) PubMed

 15697.

these data implicate PerM as a novel player in mycobacterial cell division and pathogenesis (Mus musculus) PubMed

 15698.

Data indicate that two cytochrome P450 monooxygenases from Fusarium oxysporum (FoCYP), FoCYP539A7 and FoCYP655C2, were heterologously expressed in Saccharomyces cerevisiae for efficient production of omega-hydroxy fatty acids: [CYP539A7 and CYP655C2] (Mus musculus) PubMed

 15699.

ESBL-KP isolates were less hypermucoviscous and less virulent than non-ESBL KP isolates, mostly due to concurrently lower carriage and higher mutation rates of the rmpA and rmpA2 genes [rmpA, rmpA2] (Mus musculus) PubMed

 15700.

Study describes the first structure of a DNA-complex of a uracil-DNA glycosylase from the poxvirus family and shows two D4 subunits bind simultaneously to complementary strands of the DNA double helix at the central region. [D4] (Mus musculus) PubMed

 15701.

The data support a mechanism in which benzoate tightly binds Benzoate CoA Ligase (BadA) in the thiolation conformation, followed by rotation in the active site upon ATP binding for the acyl adenylation step. [BadA] (Mus musculus) PubMed

 15702.

data showed under room temperature and anaerobic conditions, glpQ gene expression levels were higher than under other growth conditions; glpQ gene expression levels were upregulated in the presence of glycerophosphorylcholine [glpQ] (Mus musculus) PubMed

 15703.

A Ferritin A mutant lacking helix E at the 4-fold axis formed a nanocage, suggesting that helix E is not essential for nanocage formation. [Ferritin A] (Mus musculus) PubMed

 15704.

Rap60 and Phr60 controlled the activities of the transcription factors Spo0A and ComA. [Rap60, Phr60, Spo0A, ComA] (Mus musculus) PubMed

 15705.

mutants containing either upregulated (forward) or downregulated (reverse) pepc gene in Anabaena sp. PCC 7120, were constructed.[Pepc] (Mus musculus) PubMed

 15706.

WRKY4 - functions as positive regulator in the defense responses to rice sheath blight via JA/ET-dependent signal pathway (Mus musculus) PubMed

 15707.

single-nucleotide polymorphisms (SNPs) in the chicken GnIH gene among 204 individuals in Erlang mountainous chickens, were screened.[GnIH] (Mus musculus) PubMed

 15708.

These structures presented here define six distinct oligosaccharide binding sites on the surface of E. coli 1,4-alpha-Glucan Branching Enzyme. [1,4-alpha-Glucan Branching Enzyme] (Mus musculus) PubMed

 15709.

Structural data provide the details of linkage-independent sialyllactose binding by NanA carbohydrate-binding domain CBM40 and reveal striking surface features that may hold the key to recognition of binding partners on the host cell surface. [NanA] (Mus musculus) PubMed

 15710.

Alpha-catenin-dependent recruitment of the centrosomal protein CAP350 to adherens junctions allows epithelial cells to acquire a columnar shape. [alpha-catenin], [CAP350] (Mus musculus) PubMed

 15711.

FaSnRK2.6 is a negative regulator of strawberry fruit development and ripening.[FaSnRK2.6] (Mus musculus) PubMed

 15712.

study describes molecular cloning and characterization of the putative fucosidase TfFuc1(encoded by the bfo_2737 = Tffuc1 gene) [Fuc1] (Mus musculus) PubMed

 15713.

Study described the high-resolution structure of PilBac1 which exhibits the typical fold of type IV pilins with a long N-terminal alpha-helix packed against 4 antiparallel beta-strands but with significant variations in the alpha-helix and the D-region. [PilBac1] (Mus musculus) PubMed

 15714.

DNA photolyase finds and binds to a Cyclobutane Thymidine Dimer lesion 100-4000 times slower than other DNA-repair proteins. [DNA photolyase] (Mus musculus) PubMed

 15715.

A mutation in the E2 HVR1 overcomes the vesicular pH dependence, modifies the biophysical properties of particles, and drastically reduces cell-to-cell transmission. (Mus musculus) PubMed

 15716.

These data suggest that the detergent-dependent oligomeric state of OsAOS1 is an important factor for the regulation of its catalytic efficiency.[OsAOS1] (Mus musculus) PubMed

 15717.

The pvron5 gene is transcribed in the VCG-1 strain, the encoded protein is expressed at the parasite's apical pole and might participate in merozoite invasion of host cells, taking into account its marked binding preference for human reticulocytes.[RON5] (Mus musculus) PubMed

 15718.

These findings demonstrated that a functional vacuolar protein-sorting pathway mediated by FgVPS74 is crucial for fungal growth and development in F. graminearum. (Mus musculus) PubMed

 15719.

Study revealed multiple cellular roles for plc-1, splA2, and cpe-1 genes in regulation of [Ca(2+)](c), carotenoid accumulation, survival under stress conditions, and acquisition of thermotolerance induced by heat shock[Ca(2+)/H(+) exchanger (cpe-1)] (Mus musculus) PubMed

 15720.

results indicate that TrSch9 and TrYak1 play an important role in filamentous growth, stress response and induced production of cellulases in T. reesei[TrSch9] (Mus musculus) PubMed

 15721.

The data present miR-130 as a necessary linkage in the control of Fgf8 signaling, mediated by Bmp2, establishing a negative feed-back loop responsible to achieve early cardiac specification. [miR-130] (Mus musculus) PubMed

 15722.

the proposed system can be extended to detect NS1 in real samples and provide an early diagnosis of dengue. (Mus musculus) PubMed

 15723.

Data show that disruption of the sigI6 (Clo1313_2778) gene affects the solubilization pattern of switchgrass by Clostridium thermocellum: [SigI6] (Mus musculus) PubMed

 15724.

Molecular docking and dynamics results show less stable binding of rifampicin with mutant rpoB where one hydrogen bonding was found with Ser406 suggesting that rifampicin is less effective in the treatment of patients with that variant. [rpoB] (Mus musculus) PubMed

 15725.

The structure of ELR1 was first determined with the molecular replacement method, which belongs to the space group P42 21 2 with one molecule in an asymmetric unit. (Mus musculus) PubMed

 15726.

we characterized the Xenopus laevis xAtg4B protease along with two of its substrates, xLC3B and xGATE16. More specifically, we were interested in finding well-behaved and stable protease fragments with optimal proteolytic activity (Mus musculus) PubMed

 15727.

Proteolytic processing of the streptococcal IgG endopeptidase IdeS modulates the functional properties of the enzyme and results in reduced immunorecognition. [IdeS] (Mus musculus) PubMed

 15728.

A series of Quantum mechanics/Molecular Modeling optimizations of the full protein of [Fe] hydrogenase were performed. [irin hydrogenase] (Mus musculus) PubMed

 15729.

The structural basis of substrate promiscuity in UDP-hexose 4-epimerase from the hyperthermophilic Eubacterium Thermotoga maritime has been uncovered. [GalE] (Mus musculus) PubMed

 15730.

these findings reveal a genetic interaction between p7 and NS5B, as well as an interaction with sphingomyelin that regulates virion infectivity. [p7] [NS5B] (Mus musculus) PubMed

 15731.

YB-1 protects NS5A from degradation and likely regulates NS5A phosphorylation through its phosphorylation-dependent interaction with NS5A, which might be controlled by hepatitis C virus-induced signaling pathways. [NS5A] (Mus musculus) PubMed

 15732.

Molecular cloning and functional characterization of a QM protein in large yellow croaker [QM protein] (Mus musculus) PubMed

 15733.

Isolates from the Republic of Korea revealed "conserved sequences" in tryptophan-rich domain of PvTARAg55 with single amino acid substitutions (PvTARAg55). (Mus musculus) PubMed

 15734.

study to elucidate role of the active center of Ftp_Tp in Mg2+-dependent FAD hydrolysis and in potential FMN transferase activities; findings imply mechanisms by which a dynamic pool of flavin cofactor is maintained and how flavoproteins are generated by Ftp_Tp locally in the periplasm [flavin-trafficking protein] (Mus musculus) PubMed

 15735.

The cobalamin transporter BtuB was overexpressed and spin-labeled in whole cells and outer membranes and interspin distances were measured to a spin-labeled cobalamin using pulse EPR spectroscopy.[BtuB] (Mus musculus) PubMed

 15736.

A new beta-carbonic anhydrase (AgaCA, EC 4.2.1.1) from Anopheles gambiae was cloned, purified and characterized. [AgaCA] (Mus musculus) PubMed

 15737.

findings show LegK2 interacts with the ARPC1B and ARP3 subunits of ARP2/3 complex and LegK2 phosphorylates these subunits; establish that LegK2-ARP2/3 interplay inhibits actin polymerization on the Legionella-containing vacuole(LCV) and interferes with late endosome/lysosome trafficking toward the LCV [LegK2] (Mus musculus) PubMed

 15738.

Substitutions, such as PB2(E627K), were rapidly selected upon infection of humans with avian H5N1 or H7N9 influenza viruses, adapting the viral polymerase for the shorter mammalian ANP32A [PB2] (Mus musculus) PubMed

 15739.

Viral CARD and beta-hydroxysteroid dehydrogenase (beta-HSD) genes contribute to viral pathogenesis. [beta-HSD] (Mus musculus) PubMed

 15740.

Results indicate that Sip1 is a novel zinc metalloprotease that is essential to serum resistance and host infection (Sip1). (Mus musculus) PubMed

 15741.

OsGRAS23 encodes a stress-responsive GRAS transcription factor and positively modulates rice drought tolerance via the induction of a number of stress-responsive genes.[OsGRAS23] (Mus musculus) PubMed

 15742.

Finally, we show by immunohistochemistry that Na-FAR-1 is present in adult worms with a tissue distribution indicative of possible roles in nutrient acquisition by the parasite and in reproduction in the male. (Mus musculus) PubMed

 15743.

The effect of PCB 126 on aryl hydrocarbon receptor (AHR1) and AHR1 nuclear translocator (ARNT1) mRNA expression and the activity of CYP1 family monooxygenases in chicken ovarian follicles was studied.[AHR1;ARNT1] (Mus musculus) PubMed

 15744.

Data indicate that Cas6 endonuclease is necessary and sufficient for full-length CRISPR RNA (crRNA) biogenesis: [Cas6] (Mus musculus) PubMed

 15745.

This study documented the presence of mutations in the K13 gene in parasite populations from the China-Myanmar border. Mutations present in the kelch domain have become prevalent (>40%).[K13] (Mus musculus) PubMed

 15746.

GS3 and qGL3 had additive effects on rice grain length regulation.[GS3, qGL3] (Mus musculus) PubMed

 15747.

CYP79A61 might contribute to the formation of (E/Z)-phenylacetaldoxime in maize.[CYP79A61] (Mus musculus) PubMed

 15748.

cholinergic locus of ChAT and VAChT and its expression [ChAT][VAChT] (Mus musculus) PubMed

 15749.

These findings indicate that DptR3 functions as a global regulator that positively controls daptomycin production and morphological development in Streptomyces roseosporus.[DptR3] (Mus musculus) PubMed

 15750.

we have engineered an aflagellated S. Typhi DeltafliC mutant and a set of three otherwise isogenic derivatives of S. Typhi that differ only in the flagella antigen variant expressed on the surface (Hd, Hj and Hz66). (Mus musculus) PubMed

 15751.

Full-length APL1A1 and APL1B form a stable complex with LRIM1. These results support a model in which APL1A1, APL1B and APL1C can all form an extended, flexible heterodimer with LRIM1, providing a repertoire of functional innate immune complexes to protect A. gambiae from a diverse array of pathogens.[LRIM1] (Mus musculus) PubMed

 15752.

PCR positive samples showed a high prevalence of dhfr triple (Asn-108 + Arg-59 + Ile-59) mutant (68%) and dhps double (Gly -437 + Glu-540) mutant (21%). The quintuple haplotype was found in 17% with 2 samples with an additional Gly-581 mutation.[dhfr] (Mus musculus) PubMed

 15753.

In this work, the spermine-OmpF interaction was evaluated using surface plasmon resonance, and protein directionality was confirmed. [OmpF] (Mus musculus) PubMed

 15754.

NADP-isocitrate dehydrogenase (NADP-ICDH), NADP-malic enzyme (NADP-ME), glucose-6-phosphate dehydrogenase (G6PDH) and 6-phosphogluconate dehydrogenase (6PGDH), involved in the carbon metabolism and NADPH-generating system, were analyzed.[NADP-ICDH] (Mus musculus) PubMed

 15755.

OsTCTP is capable of decreasing the mercury (Hg)-induced reactive oxygen species (ROS), therefore, reducing the damage of ROS and enhancing the tolerance of rice plants to Hg stress.[OsTCTP] (Mus musculus) PubMed

 15756.

When RNR is induced in the absence of Exo1 and RNR negative regulators, cell viability of rad53 mutants treated with HU is increased and the ability of replication forks to restart after replicative stress is restored. (Mus musculus) PubMed

 15757.

Regulation of Staphylococcal Superantigen-Like Gene, ssl8, Expression in Staphylococcus aureus strain, RN6390. (Mus musculus) PubMed

 15758.

Results suggest that BapC in Bordetella pertussis Taberman parent is surface exposed when compared with the respective BapC mutant. (Mus musculus) PubMed

 15759.

The results indicate that CgPDR16 belongs to genes whose expression is induced by chemical and oxidative stresses.[PDR16] (Mus musculus) PubMed

 15760.

Neisseria meningitidis Cas9 cleaves single-stranded DNAs in a manner that is RNA guided but PAM and tracrRNA independent. [Cas9] (Mus musculus) PubMed

 15761.

Targeting of Mic10 to the mitochondrial inner membrane requires a positively charged internal loop, but no cleavable presequence. [Mic10] (Mus musculus) PubMed

 15762.

Triacylglycerol (TAG) accumulates dramatically under P starvation (by as much as ~20-fold in shoots and ~13-fold in roots), a response known to occur in green algae but hardly known in plants. [PHR1] (Mus musculus) PubMed

 15763.

Homologous transfection studies demonstrated that these genes in fact encoded the functional secretory invertases produced by these parasites. (Mus musculus) PubMed

 15764.

The GSDMB-driven HSVtk expression vector had a therapeutic effect on the occult peritoneal dissemination model mice. (Mus musculus) PubMed

 15765.

These findings support the role of a molecular tunnel in UreD as a direct facilitator of nickel transfer into urease, illustrating a new paradigm in active site metallocenter assembly. [UreD, Urease] (Mus musculus) PubMed

 15766.

The isoalloxazine moiety of the FMN residue is buried in a hydrophobic cavity and that its pyrimidine ring is squeezed between hydrophobic amino acid residues of the apo-form of NqrC. (Mus musculus) PubMed

 15767.

expression of rnf38 is negatively regulated by the serotonergic system[rnf38] (Mus musculus) PubMed

 15768.

Crystallographic and kinetic analysis of the G12A mutant hammerhead ribozyme reveals a Zn(2+) specificity switch suggesting a direct interaction between a divalent metal ion and the purine at position 12. [hammerhead ribozyme] (Mus musculus) PubMed

 15769.

Together, these results suggest that TbTim50 acts as a stress sensor and that down regulation of Tim50 could be a survival mechanism for Trypanosoma brucei exposed to oxidative stress.[Tim50] (Mus musculus) PubMed

 15770.

Thus, Toxoplasma gondii GRA17 and GRA23 provide a molecular basis for parasitophorous vacuole membrane permeability and nutrient access.[GRA17 and GRA23] (Mus musculus) PubMed

 15771.

Mutants of the sulfenic acid reductase were isolated that allowed it to act as a disulfide bond isomerase. Characterization of the mutants identified the key amino acid residues responsible for the oxidoreductase properties. [Sulfenic Acid Reductase] (Mus musculus) PubMed

 15772.

Data show that loss of RasGAP neurofibromin (NF1) enables axenic growth by increasing fluid uptake in strains HM557, HM558, and HM559: [NF1] (Mus musculus) PubMed

 15773.

the ability of the YopD central region to facilitate optimal effector protein delivery into phagocytes, and therefore robust effector Yop function, is important for Yersinia virulence. [YopD]. (Mus musculus) PubMed

 15774.

Data show that N-acetylglucosamine-responsive regulator DasR binds directly to the promoters of all genes encoding pathway-specific regulators of antibiotic production: [DasR] (Mus musculus) PubMed

 15775.

A library of promoters that can be repressed by the LuxR protein in presence of the quorum sensing autoinducer N-3-oxohexanoyl-L-homoserine lactone (AHL) was reported for Escherichia coli.[LuxR] (Mus musculus) PubMed

 15776.

Chromosomal translational hotspots are controlled by the activity of the mTOR-eIF4F pathway.[eIF4F] (Mus musculus) PubMed

 15777.

the AKT/miR-199a-5p/CAV1 pathway is identified as a regulator of innate immunity, which is dysfunctional in cystic fibrosis macrophages contributing to lung hyper-inflammation.[microrna 199a-5p] (Mus musculus) PubMed

 15778.

the mutations R575R (Angola) and V494I (Mozambique), have never been reported. V494I is adjacent to the known K13 resistance-associated mutation Y493H, although functional analysis did not predict a deleterious effect on protein function. (Mus musculus) PubMed

 15779.

Solution structure of leptospiral immunoglobulin-like protein A (LigA4 Big domain) has been presented. [LigA] (Mus musculus) PubMed

 15780.

Q beta replicase synthesizes the complementary strand as long as the template RNA is hybridized with no more than 200 nt fragments. [Q beta replicase] (Mus musculus) PubMed

 15781.

Study finds that entry of Tse6 into target cells requires its binding to an essential housekeeping protein, translation elongation factor Tu (EF-Tu). These proteins participate in a larger assembly that additionally directs toxin export and provides chaperone activity. [Tse6] (Mus musculus) PubMed

 15782.

89% of the expressed Msp2 structural variants were antigenic variants across all biological replicates, independent of a specific host major histocompatibility complex haplotype. [Msp2] (Mus musculus) PubMed

 15783.

VlsE antigenic variation is important for the enzootic cycle of Borrelia burgdorferi [VlsE] (Mus musculus) PubMed

 15784.

The localization of cocaine- and amphetamine-regulated transcript-like immunoreactive (CART-LI) in neurons of the porcine cardia is described.(CART-LI) (Mus musculus) PubMed

 15785.

Amino acid replacement in the sensor kinase LiaS contributes to the carrier phenotype.[LiaS] (Mus musculus) PubMed

 15786.

The authors describe here the activation of isolated human blood neutrophils by TcdB and, moreover, by toxin fragments generated by limited proteolytical digestion via the FPR1 receptor. (Mus musculus) PubMed

 15787.

NeqSSB-like protein is a novel highly thermostable protein which possesses a unique broad substrate specificity and is able to bind all types of nucleic acids. [NeqSSB-like protein] (Mus musculus) PubMed

 15788.

The Mga regulon but not Sda1 contributes to selection of CovRS mutations and resistance to innate immune killing.[CobR, CovS, Sda1] (Mus musculus) PubMed

 15789.

from the Porphyromonas gingivalis play roles RgpA and RgpB in regulation of angiopoietin 1 and angiopoietin 2 in human aortic smooth muscle cells.[RgpA, RgpB] (Mus musculus) PubMed

 15790.

MdsABC mediates a pathway for the survival and virulence of S. Typhimurium in phagocytic cells. [mdsA, MdsB, MdsC] (Mus musculus) PubMed

 15791.

Prickle 2 controls vertebrate core planar cell polarity protein localization and dynamics. [Prickle 2] (Mus musculus) PubMed

 15792.

Data show that cellobiohydrolase (Cel7A) from thermophilic Rasamsonia emersonii was moderately more activated by temperature than the mesophilic Hypocrea jecorina (Trichoderma reesei): [Cel7A) (Mus musculus) PubMed

 15793.

The ability of P. gingivalis DeltaluxS to induce an inflammatory response was severely impaired. [luxS] (Mus musculus) PubMed

 15794.

the defence responses of citrus canker-resistant and citrus canker-susceptible genotypes to the Xcc-derived PAMP flg22 (Xflg22) by analysing the expression of 20 citrus defence-associated genes, were compared.[flg22] (Mus musculus) PubMed

 15795.

LptA-catalysed modification of lipooligosaccharide enhances survival of Neisseria gonorrhoeae from the human inflammatory response during acute gonorrhoea. (Mus musculus) PubMed

 15796.

To understand the molecular basis for this phenotypic difference based on the candidate gene approach, B. napus FRUITFULL (FUL) homologs were identified and characterized. (Mus musculus) PubMed

 15797.

PluR and PauR both harbor substitutions in the conserved amino acid motif compared to that in AHL sensors, which appeared to be important for binding the corresponding signaling molecules (Mus musculus) PubMed

 15798.

PluR and PauR both harbor substitutions in the conserved amino acid motif compared to that in AHL sensors, which appeared to be important for binding the corresponding signaling molecules (Mus musculus) PubMed

 15799.

Consistently, LocZ supports proper Z-ring positioning at midcell.[LocZ] (Mus musculus) PubMed

 15800.

The present study demonstrated that NDGA repressed SodB activity associated with the gastric mucosal-colonization via inhibition of intracellular Fe(2+) uptake by FecA1 (Mus musculus) PubMed

 15801.

The vacA s1 allele, cagA gene, and iceA2 allele were the most prevalent . the results demonstrated a high prevalence of H. pylori virulent genotypes in Cuban patients (Mus musculus) PubMed

 15802.

DFO1 functions in maintaining rice floral organ identity to regulate epigenetic repression on OsMADS58.[DFO1,OsMADS58] (Mus musculus) PubMed

 15803.

structure of EntF holo-non-ribosomal peptide synthetase module from E coli, revealing a distinct step in the catalytic cycle [EntF] (Mus musculus) PubMed

 15804.

structure of a holo-non-ribosomal peptide synthetase module from A baumannii, revealing a distinct step in the catalytic cycle [AB3403] (Mus musculus) PubMed

 15805.

Data show that the interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) activates basophils via IgE-binding crystallin folds: [IPSE/alpha-1] (Mus musculus) PubMed

 15806.

The omega subunit of RNAP is essential in heat stress because it is required for heat acclimation of diverse cellular processes. [rpoZ] (Mus musculus) PubMed

 15807.

Results show the crystal structure of DncV and reveal the manner of GTP and ATP recognition in the pre-reaction state which explains why DncV can produce c-di-GMP and c-di-AMP, as well as 3'-5' cGAMP. [DncV] (Mus musculus) PubMed

 15808.

Results show the crystal structure of DncV and reveal the manner of GTP and ATP recognition in the pre-reaction state which explains why DncV can produce c-di-GMP and c-di-AMP, as well as 3'-5' cGAMP. [DncV] (Mus musculus) PubMed

 15809.

Structural data of FlaF protein revealed an N-terminal alpha-helix and an eight-strand beta-sandwich with striking similarity to S-layer proteins and suggest that a dimer assembly is required for in vivo function. [FlaF] (Mus musculus) PubMed

 15810.

ESX-5a region consists of the pe8, ppe15, esxP, and esxN_1 genes is involved in protein export and virulence. [pe8, ppe15, esxP, and esxN_1] (Mus musculus) PubMed

 15811.

These results indicate that duRIG-I CARD domain plays an important role in the induction of IFN-b and provide a basis for further studying the function of RIG-I in avian innate immunity (Mus musculus) PubMed

 15812.

IbeR controlled expression of stress-resistance genes and virulence genes (Mus musculus) PubMed

 15813.

Data indicate that the CT776 gene encodes an acyl-ACP synthetase (AasC) with a substrate preference for palmitic compared with oleic acid: [CT776/AasC] (Mus musculus) PubMed

 15814.

the Nab3 and Nrd1 RNA-binding proteins can attain a complex polymeric form and raise the possibility that this property is important for organizing their functional state during termination.[Nab3] (Mus musculus) PubMed

 15815.

Fission yeast Scp3 potentially maintains microtubule orientation through bundling. [Scp3] (Mus musculus) PubMed

 15816.

EepR regulated the exoenzyme production, stress survival, cytotoxicity to human epithelial cells, and virulence. [EepR] (Mus musculus) PubMed

 15817.

Tet38 efflux pump is regulated by TetR21 and contributes to the ability of S. aureus to internalize and replicate within epithelial cells. [tet38] (Mus musculus) PubMed

 15818.

the thumb subdomain of yeast mitochondrial RNA polymerase is part of an extended binding surface area involved in binding Mtf1.[Mtf1, RPO41] (Mus musculus) PubMed

 15819.

study reports T. brucei possesses a bona fide member of PSO2/SNM1 family; demonstrate that TbSNM1 activity is non-essential; however, trypanosomes lacking this enzyme are more susceptible to bi- and tri-functional DNA alkylating agents [TbSNM1] (Mus musculus) PubMed

 15820.

findings demonstrate that CspB and SleC are present exclusively in the C. perfringens SM101 spore coat layer fraction and absent in the lysate from decoated spores and from the purified inner spore membrane[CspB, SleC] (Mus musculus) PubMed

 15821.

The authors constructed a pil3 deletion mutant in a Pil3 overexpressing variant (Pil3+) and were able to demonstrate the role of Pil3 pilus in binding to colonic mucus.[Pil3] (Mus musculus) PubMed

 15822.

The CSC proteins FAP61 and FAP251 are crucial for stable and functional assembly of RS3 and that RS3 and the CSC are important for ciliary motility (FAP61 and FAP251). (Mus musculus) PubMed

 15823.

ACP interaction with a hydrophobic motif of ZmaA promotes secondary structure formation at the binding site [ZmaA] (Mus musculus) PubMed

 15824.

Pi9 and Piz-t at the Pi2/9 locus activate race specific resistance by recognizing sequence-unrelated AvrPi9 and AvrPiz-t genes, respectively.[Pi9] (Mus musculus) PubMed

 15825.

Pi9 and Piz-t at the Pi2/9 locus activate race specific resistance by recognizing sequence-unrelated AvrPi9 and AvrPiz-t genes, respectively.[AvrPi9] (Mus musculus) PubMed

 15826.

Pore hydration states of KcsA potassium channels in membranes of Streptomyces lividans has been determined. [KcsA] (Mus musculus) PubMed

 15827.

HBZ RNA is associated with genes involved in cell cycle, proliferation, and survival, while HBZ protein is more closely related to immunological properties of T cells. HBZ. (Mus musculus) PubMed

 15828.

LjGpx1 and LjGpx3 genes encode thioredoxin-dependent phospholipid hydroperoxidases and are differentially regulated in response to nitric oxide and hormones. Both are nitrosylated in vitro or in plants treated with S-nitrosoglutathione.[Gpx1,Gpx3] (Mus musculus) PubMed

 15829.

A galactomannan-binding GH2 beta-mannosidase from Caldicellulosiruptor bescii has been cloned and characterized. [GH2 beta-mannosidase] (Mus musculus) PubMed

 15830.

Although KdmA acts as transcriptional co-repressor of primary metabolism genes, it is required for full expression of several genes involved in biosynthesis of secondary metabolites.[KdmA]. (Mus musculus) PubMed

 15831.

These results suggested that LseA acts as a SNARE protein and has the potential to regulate or mediate membrane fusion events in Golgi-associated pathways.[LseA] (Mus musculus) PubMed

 15832.

Px004817 is a new juvenile hormone esterase expressed high at the early last instar. [Px004817] (Mus musculus) PubMed

 15833.

Isc1 targets plant plant salicylate biosynthesis and is a virulence factor in P. sojae. [Isc1] (Mus musculus) PubMed

 15834.

Isc1 targets plant plant salicylate biosynthesis and is required for full virulence in V. dahlia.[Isc1] (Mus musculus) PubMed

 15835.

Upc2 represents a novel class of fungal zinc cluster transcription factors, which can serve as a target for the developments of antifungal therapeutics.[Upc2] (Mus musculus) PubMed

 15836.

Airborne transmission of A/Chicken/Shandong/01/2008 (SD01) virus was related to the neuraminidase (NA) gene, and four amino acid mutations within the head region of the SD01 NA resulted in loss of airborne transmission ability in chickens.[neuraminidase] (Mus musculus) PubMed

 15837.

1-Cys TkPrx exhibits oligomeric forms with reduced peroxide reductase activity as well as decameric and dodecameric forms that can act as molecular chaperones by protecting both proteins and DNA from oxidative stress.[TkPrx] (Mus musculus) PubMed

 15838.

The channel activity of OmpG is pH dependent and the channel is gated by the extracellular loop L6. At neutral/high pH, the channel is open and permeable for substrate molecules with a size up to 900 Da. [OmpG] (Mus musculus) PubMed

 15839.

metE as a second target of the sRNA scr5239 in Streptomyces coelicolor [metE] (Mus musculus) PubMed

 15840.

Thus, the BBK32 fibronectin- and glycosaminoglycan-binding activities are separable in vivo, and BBK32-mediated glycosaminoglycan binding, but not fibronectin binding, contributes to joint colonization.[BBK32] (Mus musculus) PubMed

 15841.

heterologous expression can prevent toxic accumulation of ammonium and in return improve dehydration stress tolerance in rice (Mus musculus) PubMed

 15842.

Removal of CyanoP resulted in changes to phycobilisome coupling and energy transfer to PS II, but the function of PS II itself remained similar to wild type. [CyanoP] (Mus musculus) PubMed

 15843.

To the best of our knowledge, this is the first GST with such a wide range of pH related structural stability (Mus musculus) PubMed

 15844.

S. aureus mazEF deletion mutant was more susceptible to beta-lactam antibiotics, which suggests that further genes, putatively involved in the antibiotic stress response or cell wall synthesis or turnover, are controlled by this TA system. (Mus musculus) PubMed

 15845.

we demonstrate that each of the two presumable RNase H type I encoding genes, rnhA and MSMEG4305, can be removed from M. smegmatis genome without affecting the growth rate of the mutant (Mus musculus) PubMed

 15846.

This study described the distribution of inflammatory factors, especially insulin-like growth factor-1 and neutrophil gelatinase-associated lipocalin (NGAL).[NGAL] (Mus musculus) PubMed

 15847.

HbzIJ was demonstrated to be a maleate hydratase consisting of large and small subunits, converting maleate to enantiomerically pure d-malate. [HbzIJ] (Mus musculus) PubMed

 15848.

TonB1, but not TonB2 protein, is involved in haemin iron acquisition and that both TonB proteins are necessary for optimal bacterial virulence.[TonB1 and TonB2] (Mus musculus) PubMed

 15849.

This data indicates that BILBO1 has intrinsic polymer forming properties and that binding calcium can modulate the form of these polymers. (Mus musculus) PubMed

 15850.

RSA-2: we identify the centrosomal protein RSA-2 as a SYS-1 binding partner and show that localization of SYS-1 to mitotic centrosomes is dependent on RSA-2. (Mus musculus) PubMed

 15851.

The results demonstrate the essentiality of YeaZ for S. aureus growth and suggest that the staphylococcal YeaZ possesses regulatory function. (Mus musculus) PubMed

 15852.

rice cornichon OsCNIH1 interacts with OsHKT1;3 and enables the expression of the sodium transporter to the Golgi apparatus. (Mus musculus) PubMed

 15853.

The mapping of the sigma(54) regulon as well as the characterization of a sigma(54) mutant suggests an important role of sigma(54) not only in control of nitrogen metabolism but also in the virulence of this organism [Sigma-54] (Mus musculus) PubMed

 15854.

Based on current structural and biochemical insights in the CsgG secretion machinery, there provide a tentative model for the mem- brane translocation of unfolded protein sub- strates based on Brownian diffusion, rectified by an entropic gradient. (Mus musculus) PubMed

 15855.

It is concluded that OrrA controls sucrose synthesis in collaboration with SigB2.[OrrA, SigB2] (Mus musculus) PubMed

 15856.

Study cloned, overexpressed and biochemically characterized this invertase BfrA from L. major, data suggest that BfrA is an original invertase that is expressed in both amastigote and promastigote stages, though to a higher extent in promastigotes. [BfrA] (Mus musculus) PubMed

 15857.

Rsc1285 to control the type III secretion system and pathogenicity. [Rsc1285] (Mus musculus) PubMed

 15858.

In comparison to UDGV, UDGIV was a more efficient enzyme responsible for the removal of dU from DNA.[UDGV, UDGIV] (Mus musculus) PubMed

 15859.

EseB filament-mediated bacterial cell-cell interaction is a prerequisite for autoaggregation and biofilm formation. [EseB] (Mus musculus) PubMed

 15860.

knockdown of BANCR expression was associated with larger tumor size in C57BL/6 mice inoculated Lewis lung cancer cells.[BANCR] (Mus musculus) PubMed

 15861.

The results demonstrate that the three copper sites play related but distinct roles in CueO oxidase activities. [CueO] (Mus musculus) PubMed

 15862.

findings show that mutation G167P in cytochrome b shifts the equilibrium distribution of a head domain of iron-sulfur protein toward positions remote from the Qo site; this renders cytochrome bc1 non-functional in vivo [cytochrome bc1] (Mus musculus) PubMed

 15863.

this work establishes an expanded ability of beta-HPV 5 and 8 E6 to attenuate UV damage repair (Mus musculus) PubMed

 15864.

The phosphate transporter gene OsPht1;4 is involved in phosphate homeostasis in rice. [Pht1;4] (Mus musculus) PubMed

 15865.

tight repression of Ire1 activity by Subregion I under conditions of no or weak stress, is reported.[Ire1] (Mus musculus) PubMed

 15866.

Extracellular expression of Thermobifida fusca cutinase with pelB signal peptide depends on more than type II secretion pathway in Escherichia coli. (Mus musculus) PubMed

 15867.

we identified few compounds that particularly work against DNA ligase protein, having better interaction phenomenon and it would help further the experimental analysis. (Mus musculus) PubMed

 15868.

The high-speed tracking of fluorescence signals from single molecules revealed a complexity and heterogeneity hidden in the apparent two-state behavior of protein A folding. [protein A] (Mus musculus) PubMed

 15869.

These data support the hypothesis that reduced cholesterol uptake and increased efflux mediate luteolysis in sheep, which is partially controlled by PGF2alpha stimulation of liver X receptor (LXR) activity.[LXR] (Mus musculus) PubMed

 15870.

The hepatitis B virus singly-spliced RNA-encoded p21.5 protein inhibits HBV nucleocapsid formation. [p21.5 protein] (Mus musculus) PubMed

 15871.

SINC is a novel protein that targets nuclear envelope with capability of globally altering nuclear envelope functions in infected host cell and neighboring uninfected cells. These properties may contribute to the aggressive virulence of C. psittaci. (Mus musculus) PubMed

 15872.

To examine the effect of oxidation on cello-oligomer binding, the study uses thermodynamic integration to compute the relative change in binding free energy between the hydrolyzed and oxidized products in the active site of Cel7A and Cel6A. [Cel7A, Cel6A] (Mus musculus) PubMed

 15873.

NMR relaxation studies show that the C-terminal stretch of about 45 residues of the ribosomal P2 protein always remains as a flexible disordered domain, regardless of the state of association of the protein. [ribosomal P2 protein] (Mus musculus) PubMed

 15874.

A novel J domain protein, JDP1, was isolated from ornamental kale. The C-terminus of JDP1 specifically interacted with ARC1, which has a conserved role in self-incompatibility signaling. (Mus musculus) PubMed

 15875.

Study demonstrated that H. pylori OMV-CagA on its surface localize in proximity to ZO-1 protein in junctional area. Moreover, they induce strong histone H1 affinity to ATP in differentiated and polarized epithelial monolayers.[CagA] (Mus musculus) PubMed

 15876.

SDG711 and JMJ703 have agonistic functions in reprogramming the H3K27me3/H3K4me3 ratio and modulating gene expression in the inflorescence meristem (IM). [SDG711, JMJ703] (Mus musculus) PubMed

 15877.

Induction of miR166 and miR159 under salinity stress in solanum tuberosum represents important network hubs for balancing gene expression required for basal growth adjustments.[miR166, miR159] (Mus musculus) PubMed

 15878.

transcriptional regulation of the arsenic-responsive high affinity sulfate transporter, OsSul1;1, has been studied.[OsSul1;1] (Mus musculus) PubMed

 15879.

The authors show that Leishmania major SAS-6 crystallizes as a 9-fold symmetric cartwheel and provide the X-ray structure of this assembly at a resolution of 3.5 A.[SAS-6] (Mus musculus) PubMed

 15880.

Infrared absorption-reflection spectroscopy demonstrates that the enzyme adopts mainly beta-sheet conformation at the air-water interface before and during the compression. [beta-galactosidase] (Mus musculus) PubMed

 15881.

CRL1 positively regulates 277 genes, including key genes involved in meristem patterning (such as QUIESCENT-CENTER SPECIFIC HOMEOBOX; QHB), cell proliferation and hormone homeostasis. [CRL1] (Mus musculus) PubMed

 15882.

SAK contributes to the phenotype of Staphylococcus aureus skin infections by enhancing bacterial spreading as a result of fibrinolytic and proteolytic activation. (Mus musculus) PubMed

 15883.

The free energy profiles suggest that the energy barrier for Ca(2+) conduction is higher than that for K(+) conduction by about 4.5 kcal/mol, thus explaining the selectivity exhibited by p7 viroporin toward K(+). [p7 viroporin] (Mus musculus) PubMed

 15884.

The trigger factor adopted a compact dimeric shape at higher concentrations which did not resemble the "back-to-back" conformation reported earlier from crystallography (PDB ID: 1W26 ). [trigger factor] (Mus musculus) PubMed

 15885.

The trigger factor adopted a compact dimeric shape at higher concentrations which did not resemble the "back-to-back" conformation reported earlier from crystallography (PDB ID: 1W26 ). [trigger factor] (Mus musculus) PubMed

 15886.

This study identified the GabR-binding site on the gabT promoter; however, GabR does not bind to its own promoter.[GabR] (Mus musculus) PubMed

 15887.

This work studies the interactions of OmpF with pentameric poly-nucleotides in silico. [OmpF] (Mus musculus) PubMed

 15888.

S-enantioselective lipase and the percentage conversion were enhanced in presence of hexane. ZZ-YLIP9 was stable in all of the organic solvents used, and its activity was enhanced by solvents having logP value less than 2. (Mus musculus) PubMed

 15889.

Tin2 masks a ubiquitin-proteasome degradation motif in ZmTTK1, thus stabilizing the active kinase. (Mus musculus) PubMed

 15890.

As a key amino acid residue in the active center position, Ser-138 played an important role in maintaining the active center in the hydrophobic environment of KsdD [KsdD] (Mus musculus) PubMed

 15891.

analysis of the structure of H10N8 hemagglutinin (HA) in complex with both avian and human receptor analogues [HA, H10N8] (Mus musculus) PubMed

 15892.

bacterial heparinase II activities with defined substrates [heparinase II] (Mus musculus) PubMed

 15893.

Uptake hydrogenase HupL activity in heterocystous cyanobacteria not only supports nitrogenase activity by removing excess O2 from heterocysts but also indirectly protects the photosynthetic apparatus of vegetative cells from photoinhibition.[hupL] (Mus musculus) PubMed

 15894.

T3SS effector encoded by the MA20_12780 gene causes the incompatibility with Rj4 genotype soybeans.[MA20_12780] (Mus musculus) PubMed

 15895.

RFL regulates the LAX1 and CUC genes during AM specification, and positively influences the outgrowth of AMs though its effects on auxin transport. [RFL] (Mus musculus) PubMed

 15896.

tyrosine gate of the bacterial lectin FimH [FimH] (Mus musculus) PubMed

 15897.

Membrane cholesterol serves as an essential ligand for both CdtC and CdtB and this binding is necessary for internalization of CdtB. [CdtB] (Mus musculus) PubMed

 15898.

Results show that RamB is involved in expression control of pstSCAB operon in Corynebacterium glutamicum and identify two binding sites that are relevant for activation of pstSCAB by RamB. [RamB] (Mus musculus) PubMed

 15899.

results suggest that PdxR plays an important role in regulation of vitamin B6 metabolism, acid tolerance response and biofilm formation [PdxR] (Mus musculus) PubMed

 15900.

LpdA is a virulence factor contributing to L. pneumophila infection.[LpdA] (Mus musculus) PubMed

 15901.

PrsA2 chaperone appears to be virulence factor secretion within the host cell cytosol. [PrsA2] (Mus musculus) PubMed

 15902.

effect of polymorphism of complement system genes and Neisseria meningitidis factor H binding protein on susceptibility to invasive meningococcal disease [fHBP] (Mus musculus) PubMed

 15903.

ibpAB may be novel virulence factors for certain non-pathogenic E. coli strains [IbpA][IbpB] (Mus musculus) PubMed

 15904.

purification and characterization of an extracellular lipase from a new psychotropic strainYersinia enterocolitica KM1 [lipase] (Mus musculus) PubMed

 15905.

BacM of Myxococcus xanthus forms an extended beta-sheet structure likely mediated by hydrophobic interactions [BacM] (Mus musculus) PubMed

 15906.

Activin A contributes to the development of hyperoxia-induced lung injury in neonatal mice. [Activin A] (Mus musculus) PubMed

 15907.

CCP1 plays an important role in palea development through maintaining H3K27me3-mediated epigenetic silence of the carpel identity-specifying gene OsMADS58, shedding light on the epigenetic mechanism in floral organ development. [CCP1; MADS58] (Mus musculus) PubMed

 15908.

ABCC5 has a role in cAMP-mediated hindgut invagination in sea urchin embryos [ABCC5] (Mus musculus) PubMed

 15909.

A hibernation-promoting factor, bb0449, is not required for prolonged survival in the nutrient-limited environment in the unfed tick or any other stage of infection by B. burgdorferi. [BB0449] (Mus musculus) PubMed

 15910.

The simulations revealed multiple conformations of loops 2 and 3 in HPPK, including the open, semi-open, and closed conformations, thereby revising the previous view of the functional mechanism of the conformational change upon MgATP binding. [HPPK] (Mus musculus) PubMed

 15911.

There was a beneficial effect of Enterococcus faecium on IgA production and secretion in chicken intestine. IgA also contributed in decrease of intestinal Salmonella Enteritidis, and cytokines TGF-beta4 and IL-17 contributed to increased IgA secretion.[IgA] (Mus musculus) PubMed

 15912.

There is an overview on the importance of bldA as a regulator of morphological differentiation and antibiotic production in Streptomyces(review). (Mus musculus) PubMed

 15913.

These findings shed new light on the evolution of TRPM2 and establish nvTRPM2 as a promising tool to decipher its complex gating mechanisms. (Mus musculus) PubMed

 15914.

Free energy simulations have been conducted to study the proton transfer reaction between the catalytic residues of HTLV-1 protease using a combined quantum mechanical and molecular mechanical (QM/MM) molecular dynamics simulation. [HTLV-1 protease] (Mus musculus) PubMed

 15915.

DksA responds to changes in pH by shifting between alternate conformations [DksA] (Mus musculus) PubMed

 15916.

Elevated ldh transcription in the Deltanox strain is attributable to Rex-mediated transcriptional activation.[nox] (Mus musculus) PubMed

 15917.

RbsR was a repressor of the rbsUDK operon. [RbsR] (Mus musculus) PubMed

 15918.

Long polar fimbriae (lpf) operon is highly regulated by yhjX and hns. [ yhjX and hns] (Mus musculus) PubMed

 15919.

The fibronectin-binding protein EfbA contributes to pathogenesis and protects against infective endocarditis caused by Enterococcus faecalis. [EfbA] (Mus musculus) PubMed

 15920.

purification, characterization (optimum conditions of action, substrate specificity, reaction to surfactants and other chemicals) and gene cloining of chitinase [chitinase] (Mus musculus) PubMed

 15921.

The competence gene comEB stimulates biofilm formation via a lysis-independent mechanism of DNA release. [comEB] (Mus musculus) PubMed

 15922.

HmrA, a M20D member from S. aureus was shown as endopeptidase. [HmrA] (Mus musculus) PubMed

 15923.

M20D peptidase was so far characterized as aminoacylase. The enzyme is carboxydipeptidase and primarily specific for Met-X dipeptides. [M20D] (Mus musculus) PubMed

 15924.

M20D peptidase was so far characterized as aminoacylase. The enzyme is carboxydipeptidase and primarily specific for Met-X dipeptides. [M20D] (Mus musculus) PubMed

 15925.

KatG played acentra role in antioxidation and symbiotic nitrogen fixation by regulating the antioxidant genes. [KatG] (Mus musculus) PubMed

 15926.

O-Ag capsule-deficient mutants produced exclusively FliC protein. [FliC] (Mus musculus) PubMed

 15927.

BmAMA1 is localized on the cell surface and cytoplasm near the apical end of the parasite. [AMA1] (Mus musculus) PubMed

 15928.

The function of VND1 in regulating secondary wall deposition.[VND1] (Mus musculus) PubMed

 15929.

These findings indicate that ChsB and CsmA are transported along microtubules to the subapical region by KinA (Mus musculus) PubMed

 15930.

The SpsD520-846 and SpsL538-823 regions harboring the major fibronectin-binding sites inhibited S. pseudintermedius internalization.[SpsD and SpsL] (Mus musculus) PubMed

 15931.

The degenerate RNase III domain and a newly identified domain are critical for KREPB5 function and have differential effects between the life cycle stages of T. brucei that differentially edit mRNAs. [KREPB5] (Mus musculus) PubMed

 15932.

FasX negatively regulates the abundance of prtF1 and prtF2 mRNA transcripts. [FasX,prtF1 and prtF2] (Mus musculus) PubMed

 15933.

We propose a general role for PfTRiC in the trafficking of malarial parasite proteins to the host erythrocyte. (Mus musculus) PubMed

 15934.

finding show the operon encoding PTS Bio is repressed by NigR; described two operators to which NigR bound with different affinities [NigR] (Mus musculus) PubMed

 15935.

Lys 166 and His 297 in mandelate racemase are playing dual roles in catalysis: they act as Bronsted acid-base catalysts, and they stabilize both the enolate moiety and phenyl ring of the altered substrate in the transition state. [mandelate racemase] (Mus musculus) PubMed

 15936.

The study shows that five glutamic acid in the C-terminal domain of the ChlD subunit play a major role in conferring Mg(2+) cooperativity upon magnesium chelatase. [ChlD] (Mus musculus) PubMed

 15937.

PPR7 forms a part of a high-molecular-weight ribonucleoprotein complex in the chloroplast stroma. [PPR7] (Mus musculus) PubMed

 15938.

Crystal structure reveals that short-chain pentraxin is cyclic trimer. [short-chain pentraxin, Dare-PTX-CA, Dare-PTX] (Mus musculus) PubMed

 15939.

These results suggest Fe(II) is an important environmental signal that, via BqsRS, bolsters tolerance of a variety of cationic stressors, including clinically important antimicrobial agents.[BqsRS] (Mus musculus) PubMed

 15940.

In Streptomyces scabies, cellobiose and cellotriose inhibit the DNA-binding ability of CebR, leading to an increased expression of the thaxtomin biosynthetic and regulatory genes txtA, txtB, and txtR.[CebR] (Mus musculus) PubMed

 15941.

OsCOI1-mediated jasmonic acid signaling affects spikelet fertility and grain filling.[OsCOI1] (Mus musculus) PubMed

 15942.

The cDNA of active form of a beta-thymosin-like molecule possessed a 126-bp open reading frame that encoded a protein of 41 amino acids. Antimicrobial activity of this protein was confirmed by recombinant protein production.(beta-thymosin) (Mus musculus) PubMed

 15943.

Thus, SpyA triggers caspase-1-dependent inflammatory cell death in macrophages, revealing a toxin-triggered IL-1beta-dependent innate immune response pathway critical in defense against invasive bacterial infection.[SpyA] (Mus musculus) PubMed

 15944.

HIP2~ubiquitin conjugate forms a non-compact monomeric thioester during di-ubiquitin synthesis [HIP2] (Mus musculus) PubMed

 15945.

DnaK is important for curli production and curli-dependent biofilm formation in E. coli.[Dnak] (Mus musculus) PubMed

 15946.

These results suggest that the arginase encoded by OsARG, a key enzyme in Arg catabolism, plays a critical role during panicle development, especially under conditions of insufficient exogenous nitrogen.[OsARG] (Mus musculus) PubMed

 15947.

Protein M13 possesses a chitin binding domain & similarity to the pro-resilin family of cuticular proteins. Temporal level of M13 transcript was found in molar-forming epithelia at different molt stages (Mus musculus) PubMed

 15948.

Results suggest that ArsH catalyzes a novel biotransformation that confers resistance to environmental methylated and aromatic arsenicals.[ArsH]. (Mus musculus) PubMed

 15949.

our results demonstrate that the RhoGAP SPIN6 acts as a linkage between a U-box E3 ligase-mediated ubiquitination pathway and a small GTPase-associated defensome system for plant immunity. (Mus musculus) PubMed

 15950.

Flavonol synthase(FLS) is involved in flavonol biosynthesis in Brassica napus. [FLS] (Mus musculus) PubMed

 15951.

Together, these results support the idea that Ssl2501 encodes a cyanobacterial phasin, PhaP, which regulates the surface-to-volume ratio of polyhydroxybutyrate granules.[Ssl2501] (Mus musculus) PubMed

 15952.

Gene deletion of PXO_00049 and PXO_02374 resulted in significant increases in virulence and hrp gene transcription, indicating their negative regulation of virulence via type III secretion system expression.[PXO_00049, PXO_02374] (Mus musculus) PubMed

 15953.

Transient expression of GFP fused to the 184 N-terminal amino acids of the OspCKII sequence in rice confirmed the chloroplastic localization of the kinase. Its activity shows the characteristic features of casein kinase II.[OspCKII] (Mus musculus) PubMed

 15954.

The authors show that RRM1 associates with mRNAs and with the auxiliary splicing factor polypyrimidine tract-binding protein 2, but not with components of the core spliceosome.[RRM1] (Mus musculus) PubMed

 15955.

in E. coli, the rpsF_leader RNA is a regulatory element that inhibits the translation of rpsF. (Mus musculus) PubMed

 15956.

The results of this study demonstrate that OsIG1 plays an essential role in the regulation of empty-glume identity, floral organ number control and female gametophyte development in rice.[IG1] (Mus musculus) PubMed

 15957.

The transcription factor BadM binds to the promoter of the badDEFGAB (Bad) operon for the anaerobic conversion of benzoate to CHene-CoA to repress its expression, but BadR does not appear to control expression of the Bad operon.[BadM, BadR] (Mus musculus) PubMed

 15958.

the genomic context of HP1029 in Helicobacter and related organisms suggests a possible role in the metabolism of bacterial surface saccharides, such as pseudaminic acid and its derivatives. [HP1029] (Mus musculus) PubMed

 15959.

Rice OsNPF2.4 is located in the plasma membrane and is expressed mainly in the epidermis, xylem parenchyma, and phloem companion cells. Functional analysis in oocytes showed that OsNPF2.4 is a pH-dependent, low-affinity NO transporter.[NPF2.4] (Mus musculus) PubMed

 15960.

analysis of Pi-d2 in different strains of O. sativa and wild rice variants [Pi-d2] (Mus musculus) PubMed

 15961.

MKAN27435 is required for the biosynthesis of higher subclasses of lipooligosaccharides in Mycobacterium kansasii [MKAN27435] (Mus musculus) PubMed

 15962.

Random transposon mutagenesis identified the kfiB gene, and by inference K5 capsule biosynthesis to be important for Escherichia coli Nissle 1917 interaction with Caco-2 cells. [kfiB] (Mus musculus) PubMed

 15963.

isoamylase gene for reduced grain chalkiness in rice [ISA1] (Mus musculus) PubMed

 15964.

The antigenicity and immunogenicity of Plasmodium vivax rhoptry-associated leucine (Leu) zipper-like protein 1 (PvRALP1) was analysed. It may be immunogenic in humans and may play an important role during invasion of P. vivax parasites.[RALP1] (Mus musculus) PubMed

 15965.

These data define Hbr1 as an ATP-dependent positive and negative regulator of hyphal development that is sensitive to hypoxia. (Mus musculus) PubMed

 15966.

Glr1 and Fdh3 play differential roles during the adaptation of C. albicans cells to oxidative, nitrosative and formaldehyde stress (Mus musculus) PubMed

 15967.

found that in vivo inhibition of mTORC1 by rapamycin blocked spermatogonial differentiation[mTORC1] (Mus musculus) PubMed

 15968.

This study identified a novel mechanism whereby protein kinase A (PKA) can increase Kv7.1 current levels, namely by regulating Nedd4-2-dependent Kv7.1 transport.[PKA; Kv7.1; Nedd4-2] (Mus musculus) PubMed

 15969.

Transcriptomic and metabolomic analysis revealed a metabolic downshift of the ppx2 knockdown characterized by reduced transcription and translation and a downshift of glycerol-3-phosphate levels.[ppx2] (Mus musculus) PubMed

 15970.

Our data reveal a crucial role for a phosphodiesterase (PDEgamma) in maintaining the cyclic nucleotide balance in the malaria parasite sporozoite stage, which in turn is essential for parasite transmission from mosquito to mammal.[PDEgamma] (Mus musculus) PubMed

 15971.

MamC plays an important role in the control of the size of synthesized magnetite crystals. [MamC] (Mus musculus) PubMed

 15972.

These results suggest that rice grassy stunt virus p5 functions as a viral suppressor of RNA silencing but with a different mechanism from that of the analogous p3 the rice stripe virus, even in the same plant genus.[p3] (Mus musculus) PubMed

 15973.

These results suggest that rice grassy stunt virus p5 functions as a viral suppressor of RNA silencing but with a different mechanism from that of the analogous p3 the rice stripe virus, even in the same plant genus.[p5] (Mus musculus) PubMed

 15974.

results suggest that adherens junctions actively control cellular responses to a potent pore-forming bacterial toxin and identify PLEKHA7 as a potential nonessential host target to reduce S. aureus virulence during epithelial infections. (Mus musculus) PubMed

 15975.

rTB9.8 can activate RAW264.7 and trigger IL-6 and IL-12 p40 production via the extracellular signal-regulated kinase, p38, and NF-kappaB signaling pathways. [TB9.8] (Mus musculus) PubMed

 15976.

The regulation of WRKY45 via the ubiquitin-proteasome system is described and discussed (WRKY45). (Mus musculus) PubMed

 15977.

The authors show that Shigella flexneri IpgD phosphatase activity is required for recruitment of the ARF6 guanine nucleotide exchange factor (GEF) ARF nucleotide binding site opener (ARNO) to bacterial entry sites. (Mus musculus) PubMed

 15978.

Transcription of Leaf Panicle 2 (LP2) was directly regulated by the zinc finger transcription factor DROUGHT AND SALT TOLERANCE (DST). In addition, LP2 was identified as a functional kinase localized to the plasma membrane.[LP2,DST] (Mus musculus) PubMed

 15979.

propose that DNA repair and apoptotic-like death might be two responses mediated by the same regulators, IrrE and DdrO, but differently activated depending on the persistence of IrrE-dependent DdrO cleavage.[DdrO] (Mus musculus) PubMed

 15980.

Study shows that the Cricket Paralysis virus suppressor of RNA silencing, CrPV-1A but not B2 strongly interfere with the Ago-2-dependent miRNA silencing in Drosophila.[CrPV1-A] (Mus musculus) PubMed

 15981.

nitrate uptake in wheat is controlled by N status at flowering, with a putative major role of root nitrate transporter NRT2.1 [NRT2.1] (Mus musculus) PubMed

 15982.

Inhibition of Photosynthetic Genes by OsMADS58 [MADS58] (Mus musculus) PubMed

 15983.

A catalytically inactive [Fe]-hydrogenase paralogs have been identified. [HmdII] (Mus musculus) PubMed

 15984.

study provides evidence of new and additional roles for MAT1-1-1 in regulating asexual development and morphogenesis, as well as amino acid, iron and secondary metabolism[MAT1-1-1] (Mus musculus) PubMed

 15985.

High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction. (Mus musculus) PubMed

 15986.

These results show that Trk1 is a high-affinity K(+) transporting system efficiently discriminating between K(+) and Li(+) in Zygosaccharomyces rouxii cells. (Mus musculus) PubMed

 15987.

OsFLS2-Mediated Perception of Bacterial Flagellins Is Evaded by Xanthomonas oryzae pvs. oryzae and oryzicola [FLS2] (Mus musculus) PubMed

 15988.

the 3D structure of the p7 protein from the HCV genotypes 3 and 4, were investigated.[p7] (Mus musculus) PubMed

 15989.

Rf3 restores pollen fertility, anther exsertion and pollen shedding in cytoplasmic male sterility (Mus musculus) PubMed

 15990.

(iron superoxide dismutase) The structure of iron superoxide dismutase from Trypanosoma cruzi was identified. (Mus musculus) PubMed

 15991.

PPSA mechanism of phosphoryl transfer [PPSA] (Mus musculus) PubMed

 15992.

down-regulation of Pxwhite gene is associated with Cry1Ac resistance in P. xylostella. [Pxwhite] (Mus musculus) PubMed

 15993.

Data suggest purified ZraP is an octamer containing four interfacial metal-binding sites (located close to the N-terminus) contributing to dimer stability; zraP binds copper with a higher affinity than zinc. [zraP, Zn-dependent periplasmic chaperone] (Mus musculus) PubMed

 15994.

The structure of the complex of yeast cytochrome c peroxidase and cytochrome c, is reported.[Cytochrome c, cytochrome c peroxidase] (Mus musculus) PubMed

 15995.

IM30 establishes contacts between internal membrane sites and promotes fusion to enable regulated exchange of proteins and/or lipids in cyanobacteria and chloroplasts.[IM30] (Mus musculus) PubMed

 15996.

The results suggest that calcium regulates the maize lipoxygenase-1 reaction by binding to substrate, and by promoting binding of substrate to enzyme and association of maize lipoxygenase-1 to subcellular membranes. [lipoxygenase-1] (Mus musculus) PubMed

 15997.

The conservation of the DOF-CO module during plant evolution could be an important clue to understanding diversification by the inheritance of conserved gene toolkits in key developmental programs.[DOF, CO] (Mus musculus) PubMed

 15998.

role of phosphate in a multistep enzymatic reaction [DXR] (Mus musculus) PubMed

 15999.

FabH utilizes protein dynamics and seemingly minor sequence and structural differences to modulate its molecular recognition and substrate specificity across bacterial species.[FabH] (Mus musculus) PubMed

 16000.

FabH utilizes protein dynamics and seemingly minor sequence and structural differences to modulate its molecular recognition and substrate specificity across bacterial species.[FabH] (Mus musculus) PubMed

 16001.

the extramacrochaetae (emc) gene is required for blastokinesis in Bombyx mori. [emc] (Mus musculus) PubMed

 16002.

We identified an alp7 mutant that had specific defects in binding to the Klp5-Klp6-PP1 complex but with normal localisation to the microtubule and kinetochore. (Mus musculus) PubMed

 16003.

the functions of CsHT1, a hexose transporter from cucumber (Cucumis sativus), are studied.[CsHT1] (Mus musculus) PubMed

 16004.

These results illuminate how the four TM domains of Sho1 dictate the oligomer structure as well as its osmosensing and scaffolding functions. (Mus musculus) PubMed

 16005.

findings indicate that ARK, as a novel regulatory component integrating ABA and hyperosmosis signals, represents the ancestral B3-MAPKKKs, which multiplied, diversified, and came to have specific functions in angiosperms. (Mus musculus) PubMed

 16006.

the mature P. gingivalis FimA ab initio model of all six FimA variants, is reported.[FimA] (Mus musculus) PubMed

 16007.

Data suggest that tyrosine-phosphorylated CaM elicits strong upregulation in ligand-dependent activity of EGFR (epidermal growth factor receptor) in vitro; for these studies CaM was phosphorylated by c-Src (cellular sarcoma kinase). [CaM, calmodulin] (Mus musculus) PubMed

 16008.

the expression of two aconitase genes (Aco1 and Aco4) and activities of the mitochondrial and cytosolic forms in maize (Zea mays L.) scutellum during germination, was investigated.[Aco1, Aco4] (Mus musculus) PubMed

 16009.

identification of a gene in Lotus japonicus, Epr3, encoding a receptor-like kinase that controls Rhizobium infection [Epr3] (Mus musculus) PubMed

 16010.

Hydrogenase Activity and Proton-Gradient Regulation-Like1-Mediated Cyclic Electron Flow in Chlamydomonas reinhardtii, is reported.[Hydrogenase, PGRL1] (Mus musculus) PubMed

 16011.

The malS 5'-UTR reduces the expression of bax and increases the invasive capacity of Salmonella enterica serovar Typhi.[malS, bax] (Mus musculus) PubMed

 16012.

FaEOBII plays a regulating role in the volatile phenylpropanoid pathway gene expression that gives rise to eugenol production in ripe strawberry receptacles.[FaEOBII] (Mus musculus) PubMed

 16013.

These results describe a tri-element negative feedback loop composed of p53, Apela, and hnRNPL that regulates p53-mediated DNA damage-induced apoptosis.[Apela RNA] (Mus musculus) PubMed

 16014.

This study showed that PA5022 links swimming motility and quorum sensing, which might be an important regulator for the pathogenesis of Pseudomonas aeruginosa.[PA5022] (Mus musculus) PubMed

 16015.

It was identified eight Y. pseudotuberculosis yopD mutants with single amino acid changes affecting various type III secretion functions. (YopD protein) (Mus musculus) PubMed

 16016.

HIV Tat synergized with Orf-K1 to induce the expression of miR-891a-5p, which directly targeted IkappaBalpha 3' untranslated region, leading to NF-kappaB activation (Orf-K1). (Mus musculus) PubMed

 16017.

Cholesterol Ester Transfer Protein (CETP) is involved in serum, adipose and muscle lipid metabolism (Mus musculus) PubMed

 16018.

MgrA can serve as an intermediary regulator through which agr exerts its regulatory function. (Mus musculus) PubMed

 16019.

Streptococcus pyogenes Nox has been expressed and crystallized. The overoxidized wild-type [Cys44-SOH --> Cys44-sulfinic acid (Cys44-SO2H)] and C44S mutant enzyme structures have been refined at 2.0 and 2.15 A. Nox. (Mus musculus) PubMed

 16020.

6 crystal structures of Mtb CysQ, including a ligand-free structure, a Li-inhibited state with substrate PAP bound, and a product-bound complex with AMP, phosphate, and three Mg(2+) ions bound. CysQ. (Mus musculus) PubMed

 16021.

These results indicate that STT7-dependent phosphorylation is modulated by the environment.[STT7] (Mus musculus) PubMed

 16022.

a new member of GH130 [Dfer_3176] (Mus musculus) PubMed

 16023.

Beauveria bassiana ssk1 regulates positively the expressions of the mitogen-activated protein kinase cascade in the pathway of B. bassiana and many more downstream genes associated with conidiation, multi-stress tolerance, and virulence.[ssk1] (Mus musculus) PubMed

 16024.

the VosA-VelB hetero-complex is a key regulatory unit tightly controlling proper levels of beta-glucan synthesis in asexual and sexual spores.[VosA, VelB] (Mus musculus) PubMed

 16025.

Map-based cloning revealed that the rice (Oryza sativa L.) mutant named dwarf and tiller-enhancing 1 encodes a NOD26-LIKE INTRINSIC PROTEIN orthologous to known B channel proteins AtNIP5;1 in Arabidopsis and TASSEL-LESS1 in maize.[dte1] (Mus musculus) PubMed

 16026.

The level of RCN11/beta1,2-xylosyltransferase (OsXylT) expression was regulated by multiple phytohormones and various abiotic stresses suggesting that plant specific N-glycosylation is regulated by multiple signals in rice plants.[rcn11,OsXylT] (Mus musculus) PubMed

 16027.

OsMYB91, an R2R3-type MYB transcription factor of rice, was induced by abiotic stress. Salt stress led to rapid removal of DNA methylation from the promoter region and rapid changes of histone modifications in the locus.[MYB91] (Mus musculus) PubMed

 16028.

Three group I WRKY genes, OsWRKY24, -53, and -70, act in a partially redundant manner. However, different combinations of these WRKY genes can lead to varied strengths in suppression of their targets. (WRKY24,WRKY53,WRKY70) (Mus musculus) PubMed

 16029.

TbAos1/TbUba2 and TbUbc9 are the bona fide E1 and E2 enzymes of the SUMOylation system in T. brucei.[TbUba2, TbUbc9] (Mus musculus) PubMed

 16030.

In response to dehydration, the African clawed frog (Xenopus laevis) increased the expression of a novel gene (drp10) that encodes a structural homolog of the freeze-responsive FR10 protein found in wood frogs. [drp10] (Mus musculus) PubMed

 16031.

The oligomeric state of the gamma-carbonic anhydrase identified in the genome of Porphyromonas gingivalis has been reported. [gamma-carbonic anhydrase] (Mus musculus) PubMed

 16032.

Hypoxic exposure (oxygen partial pressure = 5 kPa) in turn caused a significant increase in the level of Hif-1alpha protein even at 1 days post fertilization and in later stages, while neither Hif-2alpha nor Hif-3alpha protein level were affected.[Hif3 alpha] (Mus musculus) PubMed

 16033.

Data suggest NanS is novel, highly active, neutral sialate-O-acetylesterase that removes 9-O-acetyl groups from sialoglycoproteins; NanS works with NanH (T. forsythia sialidase) to hydrolyze human erythropoietin and bovine sialomucins. [NanS] (Mus musculus) PubMed

 16034.

the cca-3 resistance gene was able to induce hypersensitive responses to infection by the target leaf spot pathogen (Mus musculus) PubMed

 16035.

Human APOBEC3G C-terminal directly binds hepatitis C virus non-structural protein NS3 at its C-terminus.[NS3] (Mus musculus) PubMed

 16036.

the mechanism of light induced protein conformational changes in the over-expressed mutant of halorhodopsin (phR) from Natronomonas pharaonis [phR] (Mus musculus) PubMed

 16037.

Hsc70-4 controls rejuvenation of the synaptic protein pool in a dual way: either by refolding proteins together with Sgt, or by targeting them for degradation by facilitating endosomal microautophagy based on its membrane deforming activity. (Mus musculus) PubMed

 16038.

Deletion of both waaL ligase genes lead to a drastic reduction in bacterial motility and increase their sensitivity to hypertonic medium that can indirectly characterize biological role of WaaL ligases. (Mus musculus) PubMed

 16039.

A mathematical model of H3K76 methylation during the trypanosome cell cycle suggests that temporally-regulated consecutive action of TbDot1A and TbDot1B is required for the observed regulation of H3K76 methylation states. (Mus musculus) PubMed

 16040.

The crystal structure of the CptIN protein-RNA complex reveals a new heterotetrameric quaternary organization for the Type III toxin-antitoxin class (CptIN). (Mus musculus) PubMed

 16041.

In this work, through an in silico comparative analysis between the genomes of Leishmania major and Homo sapiens, the enzyme ribose 5-phosphate isomerase (R5PI) was indicated as a promising molecular target.[R5PI] (Mus musculus) PubMed

 16042.

Proteomic responses to a methyl viologen-induced oxidative stress in the wild type and FerB mutant strains of Paracoccus denitrificans. (Mus musculus) PubMed

 16043.

TAR1 is a regulator of triacylglycerol accumulation in nitrogen or sulfur-deficient conditions.[TAR1] (Mus musculus) PubMed

 16044.

Cloning, expression, purification, crystallization and X-ray crystallographic analysis of CofB, the minor pilin subunit of CFA/III from human enterotoxigenic Escherichia coli has been reported. [CofB] (Mus musculus) PubMed

 16045.

Expression, purification, crystallization and preliminary X-ray analysis of CttA, a putative cellulose-binding protein from Ruminococcus flavefaciens, has been reported/ [CttA] (Mus musculus) PubMed

 16046.

Overexpression, purification, crystallization and preliminary X-ray diffraction of the nisin resistance protein from Streptococcus agalactiae has been reported. [NSR] (Mus musculus) PubMed

 16047.

A preliminary X-ray study of 3-deoxy-D-manno-oct-2-ulosonic acid 8-phosphate phosphatase (YrbI) from Burkholderia pseudomallei has been reported. [YrbI] (Mus musculus) PubMed

 16048.

Crystallization and preliminary X-ray diffraction analysis of the Csu pili CsuC-CsuA/B chaperone-major subunit pre-assembly complex from Acinetobacter baumannii has been reported. [CsuA],[CsuB],[CsuC] (Mus musculus) PubMed

 16049.

Transcriptomic analysis of the mutant deficient in the LuxR-type regulator AcsR showed that the acsA gene encoding acetyl-CoA synthetase was down-regulated.[AcsR, AcsA] (Mus musculus) PubMed

 16050.

The different reactivity of DgAOR versus aldehyde oxidase and XO towards aromatic aldehydes and N-heterocyclic compounds is explained on the basis of the present kinetic and structural data (Mus musculus) PubMed

 16051.

Fusion gene (ORF 117)of sheeppox virus an analogue of vaccinia virus A27L gene. [Fusion gene] (Mus musculus) PubMed

 16052.

Bom m 9 protein induced allergic asthma in a mouse model. [ Bom m 9] (Mus musculus) PubMed

 16053.

These results suggest a potentially conserved mechanism of pedicel AZ development in apple and other plants, regulated by MADS-box transcription factors.[MdJa, MdJb] (Mus musculus) PubMed

 16054.

dynamical communication between the protein dimer surface and substrate- and cofactor-binding domains (Mus musculus) PubMed

 16055.

Soybean ADF2 interacts with Soybean mosaic virus-encoded P3 protein. [P3] (Mus musculus) PubMed

 16056.

The SPL29 gene was confirmed as UDP-N-acetylglucosamine pyrophosphorylase 1 (UAP1). Based on the findings of this study, it is suggested that UAP1 is involved in regulating leaf senescence and defence responses in rice.(UAP1) (Mus musculus) PubMed

 16057.

mechanism of transpeptidase reaction of PBP4 protein [PBP4] (Mus musculus) PubMed

 16058.

Both VSG 397 and VSG 653 were activated during development from procyclics to infectious metacyclic forms.[VSG 397, VSG 653] (Mus musculus) PubMed

 16059.

Rice is capable of activating basal resistance against rice blast by perturbing OsDCL1-dependent miRNA biogenesis pathway. [OsDCL1] (Mus musculus) PubMed

 16060.

OsiSAP7 acts as a negative regulator of ABA and water-deficit stress signalling by acting as an E3 ubiquitin ligase. [OsiSAP7] (Mus musculus) PubMed

 16061.

Tetrahymena TERT RNA-binding domain is wedged into the base of the template boundary element RNA stem-loop, and each of the flanking RNA strands wraps around opposite sides of the protein domain.[TERT] (Mus musculus) PubMed

 16062.

This work shows that Sph3 is a glycoside hydrolase essential for GAG production and defines a new glycoside hydrolase family, GH135. [Sph3] (Mus musculus) PubMed

 16063.

epsilon subunit of DNA polymerase III plays a distinct role in replisome disassembly and/or processing of stalled replication forks.[DnaQ] (Mus musculus) PubMed

 16064.

The present data indicate that ferredoxin II is a major Ca(2+) binding protein in Mesorhizobium loti that may participate in Ca(2+) homeostasis.[ferredoxin II] (Mus musculus) PubMed

 16065.

The meningococcal MafB proteins are novel toxic proteins involved in interbacterial competition.[MafB] (Mus musculus) PubMed

 16066.

In the case of MoaX, post-translational cleavage at the Gly82 residue is required for function.[MoaX] (Mus musculus) PubMed

 16067.

key roles for the distal pocket histidine in cytochrome C nitrite reductases [NrfA] (Mus musculus) PubMed

 16068.

key roles for the distal pocket histidine in cytochrome C nitrite reductases [NrfA] (Mus musculus) PubMed

 16069.

this study identified a novel beta-1,4-mannanase (Man134A) that belongs to a new glycoside hydrolase (GH) family (GH134) in Aspergillus nidulans. [ANID_02710] (Mus musculus) PubMed

 16070.

A 50.3% decrease in CO2 emission; and a 3.8-fold increase in AA production was observed in the budA(-) strain SGSB106. Valine production increased, suggesting that the branched-chain AA biosynthesis in SGSB106 was activated by deletion of budA. budA. (Mus musculus) PubMed

 16071.

We review here the recent literature dealing with the molybdenum- and copper-dependent CO dehydrogenase, with particular emphasis on the structure of the enzyme (Mus musculus) PubMed

 16072.

In vitro clipping assays confirmed the ability of both Neisseria meningitidis proteins, App and MspA, to proteolytically cleave the core histone H3.[MspA] (Mus musculus) PubMed

 16073.

this study determined molecular structures of the catalytically active Streptococcus pyogenes Cas9 R-loop that show the displaced DNA strand located near the RuvC nuclease domain active site. [Cas9] (Mus musculus) PubMed

 16074.

Pasteurella multocida toxin induces the differentiation of RAW264.7 macrophages into multinucleated, tartrate resistant acid phosphatase (TRAP) positive osteoclasts that are capable to resorb bone. [pasteurella multocida toxin] (Mus musculus) PubMed

 16075.

DNA sequencing were used to characterize the outer membrane porin genes and the resistance genes mediating the common beta-lactamases and carbapenemases. Synergism was evaluated by time-kill studies. The bla SHV-31, bla CMY-2, and bla DHA-1 were detected (Mus musculus) PubMed

 16076.

This novel assay has successfully detected both the 3'P (3'-Processing Integrase) activity of HIV-1 IN and the anti-IN activity by Raltegravir and sodium azide agent. (Mus musculus) PubMed

 16077.

Here the authors have identified and characterised the function of the TFIIEbeta homologue in archaea that on the primary sequence level is related to the RNAPIII subunit hRPC39.[TFIIEbeta] (Mus musculus) PubMed

 16078.

MiR-13 attenuates viral infection via modulating major capsid protein expression.[Mir-13] (Mus musculus) PubMed

 16079.

Two new entries: TRPV1 is expressed in pineal photoreceptor cells, in which they modulate melatonin secretion in vitro. TRPV4 is expressed in pineal photoreceptor cells, in which they modulate melatonin secretion in vitro. (Mus musculus) PubMed

 16080.

WRKY70-dependent jasmonic acid biosynthesis is required for proteinase inhibitor activation and resistance against Chilo suppressalis.[WRKY70] (Mus musculus) PubMed

 16081.

Structural studies in these DgAOR samples have demonstrated that the Mo-FeS 1 bridging pathway does not show significant differences, confirming that the changes in J observed upon inhibition cannot be ascribed to structural changes (Mus musculus) PubMed

 16082.

TBX-2 itself directly represses its own expression in a negative autoregulatory loop.[TBX-2] (Mus musculus) PubMed

 16083.

ZnuABC also plays an important role in zinc homeostasis in this microorganism.[ZnuA, ZnuB, ZnuC] (Mus musculus) PubMed

 16084.

PGKA is the predominant isoenzyme for sustaining glycolysis through the glycosomes. [PKGA] (Mus musculus) PubMed

 16085.

chs7 is dispensable for fruiting body formation in S. macrospora, whereas sec22 is required for ascospore maturation and germination and thus involved in late stages of sexual development.[chs7, sec22] (Mus musculus) PubMed

 16086.

characterization of a UDPglucose dehydrogenase [udp-glucose dehydrogenase] (Mus musculus) PubMed

 16087.

Suggestions can be made that CKIIalpha2 governs chitinase expression, and the disruption of ck2alpha2 results in lower levels of chitinase production.[CKIIalpha2] (Mus musculus) PubMed

 16088.

single copy of Tc8.2 in the T. cruzi genome and 2-different sized transcripts in epimastigotes/amastigotes and trypomastigotes. [Tc8.2] (Mus musculus) PubMed

 16089.

Crystal structure of CheA from Thermotoga maritima. [CheA] (Mus musculus) PubMed

 16090.

These findings reveal the role of HAX-1 in regulating cyclophilin-D levels via an Hsp90-dependent mechanism, resulting in protection against activation of mPTP and subsequent cell death responses.[mPTP] (Mus musculus) PubMed

 16091.

Directed evolution was used to explore allosteric regulation as a source of latent catalytic potential using the beta-subunit of tryptophan synthase from Pyrococcus furiosus.[TrpB] (Mus musculus) PubMed

 16092.

Conserved charged amino acids and a proline residue of MprF are crucial for flippase activity. [MprF] (Mus musculus) PubMed

 16093.

B cell receptor (IgM) cross-linking by protein A is an important immune evasion strategy of S. aureus. [SpA] (Mus musculus) PubMed

 16094.

Structure and function of Caulobacter crescentus aldose-aldose oxidoreductase. (Mus musculus) PubMed

 16095.

the LacI-family transcriptional regulator MalR represses the expression of the mal regulon in the absence of maltose.[MalR] (Mus musculus) PubMed

 16096.

These results indicate that the DnaJ of Streptococcus suis type 2 is important not only for thermotolerance but also for adhesion to host cells.[DnaJ] (Mus musculus) PubMed

 16097.

Lst scavenge sialic acid from the host and use it to modify lipooligosaccharide. [Lst] (Mus musculus) PubMed

 16098.

Results indicate that KPNA3 knockdown eliminates the second heat shock protein peak in the heat shock response of male silkworm pupae by reducing HSF transport into the nucleus. (Mus musculus) PubMed

 16099.

the combination of the IgM detection with NS1 detection or both NS1 and IgG resulted in a significant (p < 0.001) increase in sensitivity to 97.5% (95 % CI: 92.9-99.2) and 98.9% (95 % CI: 96.0-99.7), respectively. (Mus musculus) PubMed

 16100.

RovS and its associated signaling peptide are required for Streptococcus agalactiae pathogenesis. [RovS] (Mus musculus) PubMed

 16101.

Results identified the HXE motif involved in the formation of the ternary complex required for the proper catalytic activity of TlGK rather than in regulation of its activity by free divalent cations. {TIGK] (Mus musculus) PubMed

 16102.

A new salicylate synthase, namely AmS, was identified in the biosynthesis pathway of siderophore amychelin in Amycolatopsis methanolica 239(T), since it shunt chorismate, an integrant precursor, from primary to secondary metabolite flow. (Mus musculus) PubMed

 16103.

Results suggest that the amount of stabilization energy of the reaction intermediate provided by Low-barrier hydrogen bonds is small compared with that provided by an ordinary hydrogen bond in KSI. [KSI] (Mus musculus) PubMed

 16104.

Vat affect the motility, agglutination, biofilm formation and virulence of avian pathogenic Escherichia coli. [vat] (Mus musculus) PubMed

 16105.

Data suggest beta-lactam drug resistance of methicillin-resistant S. aureus (MRSA) from clinical isolates in South Korea is mecA-dependent; morin/oxacillin synergism reduces mecA/drug resistance of MRSA. [mecA, PBP2A; penicillin-binding protein 2A] (Mus musculus) PubMed

 16106.

AvrPtoB regulates HopAD1-triggered host cell death.[AvrPtoB] (Mus musculus) PubMed

 16107.

BDP1 critically coordinates expression of invasion genes.BDP1 binds to chromatin at invasion gene promoters. [BDP1] (Mus musculus) PubMed

 16108.

LuxS expression level was the lowest in the lag phase and began increasing when entered index phase. [luxS] (Mus musculus) PubMed

 16109.

Seventy-two A. fumigatus clinical isolates from China were investigated for azole resistance based on mutations of cyp51A (Mus musculus) PubMed

 16110.

Results show that activity pectate lyase is lost at low pH because protonation of aspartates results in the loss of the two catalytic calcium-ions causing a profound failure to correctly organize the Michaelis complex. [pel] (Mus musculus) PubMed

 16111.

The various conformations of oxidized Hsp33 explored by NMR spectroscopy. [Hsp33] (Mus musculus) PubMed

 16112.

Molecular cloning and preliminary function of F-spondin gene show the gene is expressed highly in the ovary implied and involved in the development of the teleost nervous system. [F-spondin] (Mus musculus) PubMed

 16113.

The study investigates the structural determinants of the substrate spectrum in the zinc-dependent Alcohol Dehydrogenase carbonyl reductase 2 (CPCR2), combining methods of mutational analysis with in silico substrate docking. [CPCR2] (Mus musculus) PubMed

 16114.

An APETALA1-like gene from Nelumbo nucifera has been cloned and expressed. [APETALA1(AP1)] (Mus musculus) PubMed

 16115.

MATE2 is localized in the Golgi complex and expressed in leaves.MATE2 encode putative proanthocyanidin transporters expressed during berry development.[MATE1] (Mus musculus) PubMed

 16116.

structural, functional studies and molecular dynamics simulations indicate that these subunits rotate with respect to the integral membrane beta-barrel of BamA to induce movement of the beta-strands of the barrel and promote insertion of the nascent OMP [BamA] (Mus musculus) PubMed

 16117.

the starfish-like TssA dodecameric complex interacts with tube and sheath components [TssA] (Mus musculus) PubMed

 16118.

The authors found that the deletion of either yvqE or yvqEC weakened the resistance of Bacillus thuringiensis against vancomycin.[yvqEC] (Mus musculus) PubMed

 16119.

Data show the cloning, purification, and characterization of the NSAAR enzyme and evaluate its N-formyl-amino acid racemase activity. It confirmed K166, D191, E216, D241, and K265 as key residues for its activity, but not for substrate binding. {NSAAR] (Mus musculus) PubMed

 16120.

The set of active site residues that define substrate specificity in the amidohydrolase EgtC are highly conserved, even in homologues that are not involved in ergothioneine production. [EgtC] (Mus musculus) PubMed

 16121.

These results support a model where residual ACT1 protein retained in inducible Deltaact1 parasites facilitates their limited invasive ability and confirm that parasite actin is essential for efficient penetration into host cells during invasion.[actin] (Mus musculus) PubMed

 16122.

Peptides containing C-terminal 15 amino acids of EscI protein can significantly induce NLRC4 inflammasome activation in macrophages. [EscI] (Mus musculus) PubMed

 16123.

XC3176 is a Type III secretion system effector and it is required for the full virulence of Xcc 8004.[XC3176] (Mus musculus) PubMed

 16124.

This study investigates how NADH oxidase structure and dynamics are affected by changes in temperature, the addition of urea and the substitution of the flavin mononucleotide cofactor with flavin-adenine dinucleotide. [NADH oxidase] (Mus musculus) PubMed

 16125.

Overall, the data suggest that some Sap, particularly Sap2, are proinflammatory proteins in vivo and can mediate the inflammasome-dependent, acute inflammatory response of vaginal epithelial cells to Candida albicans.[Sap2] (Mus musculus) PubMed

 16126.

The data implied that PhoPQ was induced by low pH in the flea gut, and that PhoP modulated physiological adaptation to acid and other stresses encountered during infection of the flea.[PhoPQ] (Mus musculus) PubMed

 16127.

Radiotherapy suppressed specific recruitment of regulator CD4+CD25+ Treg cells in Lewis lung carcinoma via up-regulating microR-545. (Mus musculus) PubMed

 16128.

The mutagenesis data described herein indicate that the minimal cytolytic unit of Streptolysin S encompasses the N-terminal poly-heterocyclizable region of the core peptide. (Mus musculus) PubMed

 16129.

The role of two types of quinones, 1,2- and 1,4-benzoquinone, in the operation and mechanism of the electron transfer in PQQ-Glucose Dehydrogenase anodes has been addressed. [PQQ-Glucose Dehydrogenase] (Mus musculus) PubMed

 16130.

The SaeS protein is the histidine kinase responsible for phosphorylation of the response regulator SaeR. RNA-Seq results indicated that sae regulates many genes that may affect biofilm formation (Mus musculus) PubMed

 16131.

Determined the neutron structure of PcyA complexed with biliverdin IXalpha, revealing the exact location of the hydrogen atoms involved in catalysis. [PcyA] (Mus musculus) PubMed

 16132.

Genome sequencing revealed a large macrolide Polyketide Synthase gene cluster that codes for the biosynthesis of rosamicin A and a series of new macrolide antibiotics. [Rosamicin Polyketide Synthase] (Mus musculus) PubMed

 16133.

These findings suggest that nuclear factor kappa B(NF-kappaB) and cyclooxygenase-2 play roles in epidermal cell regeneration following beta-irradiation of mini-pig skin.[NF-kappa B] (Mus musculus) PubMed

 16134.

Taken together, these results revealed a novel role of RfaH acting as a highly specific regulator of O-antigen and outer core of lipopolysaccharide in Yersinia enterocolitica O:3.[RfaH] (Mus musculus) PubMed

 16135.

These findings suggest that c-di-GMP directly interferes with the interaction of CRP-cAMP and the gbpA promoter via an unidentified regulator to govern GbpA expression. (Mus musculus) PubMed

 16136.

These results provide new evidence for the roles of non-type III effector genes HrpL, iaaL and matE, belonging to the Pto DC3000 HrpL regulon, in virulence.[matE] (Mus musculus) PubMed

 16137.

Biochemical analysis demonstrated that these five putative aspartate aminotransferases have authentic aspartate aminotransferases activity in vitro: alr1039, all2340, alr2765, all4327 and alr4853.[alr1039, all2340, alr2765, all4327 and alr4853] (Mus musculus) PubMed

 16138.

The C-terminal tail of MoaA provides an essential mechanism to trigger the free radical reaction, impairment of which results in the complete loss of catalytic function of the enzyme. [Moaa] (Mus musculus) PubMed

 16139.

Bovine neutrophils, the major effector cells in the defense against staphylococci, express significant cell surface levels of CCR1, that binds staphylococcal leukocidin LukMF leading to cell death.[LukMF'] (Mus musculus) PubMed

 16140.

A viral microRNA miR-K12-11 deletion mutant of Kaposi Sarcoma-Associated Herpesvirus was found to be defective for induction of HO-1 during latency.[miR-K12-11] (Mus musculus) PubMed

 16141.

DacA is a diadenylate cyclase, which synthesizes cyclic diadenosine monophosphate in Streptococcus suis serotype 2. [DasA] (Mus musculus) PubMed

 16142.

A novel variant of the beta-lactamase ADC-61 gene in multi-drug resistant Acinetobacter baumannii has been identified. (Mus musculus) PubMed

 16143.

Taken together, these findings indicate that posttranslational rhamnosylation of elongation factor P plays a key role in Pseudomonas aeruginosa gene expression and survival.[elongation factor P] (Mus musculus) PubMed

 16144.

The authors propose that, during prolonged starvation, relief of CsrA repression permits CsrR protein to coordinate Legionella pneumophila's switch to a cell type that is resilient in water supplies.[CsrR] (Mus musculus) PubMed

 16145.

a bacterial FA hydratase that can convert C20 and C22 PUFAs into the corresponding hydroxy FAs [FA-HY1] (Mus musculus) PubMed

 16146.

PtVP1.1 is a functional counterpart of Arabidopsis vacuolar H(+)-pyrophosphatase and can be genetically engineered for salt tolerance improvement in trees.[PtVp1.1] (Mus musculus) PubMed

 16147.

GadD3 encodes a glutamate decarboxylase dedicated to the intracellular GAD system, which produces GABA from cytoplasmic glutamate in the absence of antiport activity.[GadD3] (Mus musculus) PubMed

 16148.

VEL1 of Trichoderma reesei regulates sexual and asexual development and is essential for cellulase gene expression.[vel1] (Mus musculus) PubMed

 16149.

OsARF16 is involved in cytokinin-mediated inhibition of phosphate transport and phosphate signaling in rice. [arf16] (Mus musculus) PubMed

 16150.

GadD2 maintain both an intracellular and extracellular GAD system.[GadD2] (Mus musculus) PubMed

 16151.

An interaction of Aha1 with Hsp90 takes place at different positions than previously described.[Aha1] (Mus musculus) PubMed

 16152.

Upon deletion of Zur transcriptional repressor, exposure to different zinc and copper conditions induced complementary homeostatic mechanisms (ATPase efflux proteins) to control the intracellular concentrations of zinc. [Zur transcriptional repressor] (Mus musculus) PubMed

 16153.

the lrp1 promoter is a direct target of RUM1 proteins.[RUM1] (Mus musculus) PubMed

 16154.

ROP10, of Medicago truncatula is localized at the plasma membrane (PM) of root hair tips to regulate root hair tip growth.[ROP10] (Mus musculus) PubMed

 16155.

The study reports the vibrational spectroscopic characterisation of a catalytic intermediate formed by the reaction of H2O2 with Dye-decolourising peroxidase immobilised on a biocompatible coated metal support. [Dye-decolourising peroxidase] (Mus musculus) PubMed

 16156.

Conformational changes in eIF2Balpha2(betadelta)2 might regulate its interactions with eIF2 (eIF2Balpha, eIF2Bbeta and eIF2Bdelta). (Mus musculus) PubMed

 16157.

The results of this study showed that avoidance of autophagy primarily involves PlcA and ActA and that either one of these factors must be present for Listeria monocytogenes growth in macrophages.[PlcA and ActA] (Mus musculus) PubMed

 16158.

The data summarized here show that M36 and M38 of CusB are important residues for both the Cu(I) coordination to the CusB N-terminal domain and the interaction with CusF, and K32 is essential for the interaction with CusF. [CusB, CusF] (Mus musculus) PubMed

 16159.

It is likely that the O-glycosylated form of the A. niger ENG1 retains more stable activity during continuous cultivation of recombinant yeasts than the form that is only N-glycosylated (Mus musculus) PubMed

 16160.

Data suggest that mutations in HMG-CoA reductase, cyp51A (lanosterol 14-alpha demethylase), and erg25 (C-4 methyl sterol oxidase) contribute to multi-drug-resistance to azole antifungal agents. [HMG-CoA reductase] (Mus musculus) PubMed

 16161.

Taken together, our findings reveal that Cnm is a colonization factor that contributes to the pathogenicity of certain Streptococcus mutans strains in their native habitat, the oral cavity.[Cnm] (Mus musculus) PubMed

 16162.

These observations suggest that the Cys194 reactivity is negatively affected by a posttranslational modification of the adjacent Tyr193 residue, which interacts with flavin mononucleotide and the substrate in the NbaA catalytic site.[NbaA] (Mus musculus) PubMed

 16163.

A major plant height quantitative trait loci, qph1, was mapped to a 1.6kb interval in Brachytic2 (Br2) coding sequence on maize chromosome 1.[Brachytic2] (Mus musculus) PubMed

 16164.

These results suggested that higher Ascorbate peroxidase activity in transgenic lines increases the salt tolerance by enhancing scavenging capacity for reactive oxygen spe-cies under NaCl stress conditions (Mus musculus) PubMed

 16165.

Cas9 endonuclease activity is strongly inhibited when its target site is located within the nucleosome core. In contrast, the nucleosome structure does not affect Cas9 activity at a target site within the adjacent linker DNA. [Cas9] (Mus musculus) PubMed

 16166.

The authors identified low molecular weight thiols, particularly glutathione, as the signal sensed by a periplasmic cysteine residue (C62) on the histidine kinase sensor VirA.[VirA] (Mus musculus) PubMed

 16167.

An alanine racemase-deficient mutant strain was compared with the parental strains for their growth in the presence and absence of exogenous d-alanine. The mutant cells showed cell wall damage and increased membrane permeability.[alanine racemase]. (Mus musculus) PubMed

 16168.

This study reveal the molecular basis for how thymine-7-hydroxylase recognizes different substrates and catalyses the consecutive oxidations and provide new insights into the molecular mechanism of the substrate recognition and catalysis (thymine-7-hydroxylase). (Mus musculus) PubMed

 16169.

A novel CalB-type lipase (PlicB) discovered by fungal genomes mining. [PlicB] (Mus musculus) PubMed

 16170.

Ivy1, the yeast homolog of mammalian missing-in-metastasis (MIM), is a vacuolar effector of Ypt7-GTP and interacts with the EGO/ragulator complex.[Ivy1, Ypt7] (Mus musculus) PubMed

 16171.

Xpo1 and Ran[GTP] together reduce the RNA-stimulated ATPase and helicase activities of Ded1.[Xpo1, Ded1, Ran] (Mus musculus) PubMed

 16172.

there is a co-localization of disulphide bridges and N-linked glycans in HIV-1 gp120, with a predominance of N-linked glycans in close proximity to disulphide bridges, at the C-terminal side of the involved cysteines.[gp120] (Mus musculus) PubMed

 16173.

Together, these data strongly suggest that hfq plays important roles in the virulence of Cronobacter sakazakii by participating in the regulation of multiple genes.[hfq] (Mus musculus) PubMed

 16174.

Data suggest that Hig expressed in neurons of female Aedes aegypti brain contributes to reduced infection by Flaviviruses (Dengue virus and Japanese Encephalitis virus, but not Sindbis virus). [Hig; homologue of Hikaru genki protein (Drosophila)] (Mus musculus) PubMed

 16175.

The interaction between C4BP and Leptospira interrogans LcpA, LigA and LigB is sensitive to ionic strength and inhibited by heparin.[LigA, LigB] (Mus musculus) PubMed

 16176.

Skp is not an obligate trimer under physiological conditions and Na(+), Cl(-), Mg(2+), and PO4(3-) ions are not linked to Skp trimerization. [Skp] (Mus musculus) PubMed

 16177.

the Vibrio cholerae FadR 40 residue insertion facilitates binding of an additional fatty acyl-CoA ligand [fadR] (Mus musculus) PubMed

 16178.

Data suggest Asd4 (GATA type zinc finger protein 4) regulates expression of genes involved in nitrogen assimilation/glutaminolysis; strain lacking Asd4 expresses Gln1 and cannot form appressoria required to infect host. [Gln1; glutamine synthetase 1] (Mus musculus) PubMed

 16179.

The MglA structure revealed that it contains a fold similar to the SspA protein family.[MglA] (Mus musculus) PubMed

 16180.

The aim of this study was to investigate the impact of the substitution at position 70 in hepatitis c virus core protein on adipokine production by murine and human adipocytes.[Core protein] (Mus musculus) PubMed

 16181.

These results indicate that fusion pBD2 is functional and has similar properties to those of pBD2 from the native gene. Our current study demonstrated that codon optimization could enhance pBD2 expression in E. coli without altering its function (Mus musculus) PubMed

 16182.

We concluded that CDPK2 as well as all the other CDPK genes in T. gondii cannot be used as proper markers for studying the variants of different T. gondii genotypes from different hosts and geographical locations (Mus musculus) PubMed

 16183.

Data suggest that continued expression of SigB plays a crucial function in promoting bacterial intracellular persistence during chronic Staphylococcus aureus infections. [SigB; sigma-B factor protein] (Mus musculus) PubMed

 16184.

A mutant lacking all susC-like and all susD-like genes digested cellulose and grew on cellulose as well as wild-type cells.[susC, susD] (Mus musculus) PubMed

 16185.

This study reports the kinetics/affinities of the heme nitric oxide/oxygen binding protein, H-NOX for CO, NO, and O2. [H-NOX] (Mus musculus) PubMed

 16186.

The study reports the X-ray crystal structure of the unliganded N-terminal domain of Geosmin Synthase and the structure of its complex with three Mg(2+) ions and alendronate. [Geosmin Synthase] (Mus musculus) PubMed

 16187.

Photosystem II electron transfer properties are influenced by Flv2, Flv4, and Sll0218.[Flv2, Flv4, and Sll0218] (Mus musculus) PubMed

 16188.

All methicillin-resistant strains of Staphylococcus aureus isolated from cancer patients in a Spanish hospital had the chromosomal cassette SCCmecA and did not produce Panton-Valentine toxin [mecA]. (Mus musculus) PubMed

 16189.

The electrons required for ribonucleotide reduction can be delivered by a ferredoxin disulfide reductase to class III ribonucleotide reductase. [ferredoxin disulfide reductase, class III ribonucleotide reductase] (Mus musculus) PubMed

 16190.

DnaK protein alleviates toxicity induced by citrate-coated gold nanoparticles in Escherichia coli BB1553. [DnaK] (Mus musculus) PubMed

 16191.

Results suggested that detection of catecholamines and iron by QseBC may alter the cellular metabolism of A. actinomycetemcomitans for increased fitness and growth in an anaerobic host environment[QseB, QseC] (Mus musculus) PubMed

 16192.

the involvement of a Hik8-cascade in the expression of genes involved in the glycolytic and OPP pathways induced by Glucose-plus-pulsed light, is shown.[Hik8] (Mus musculus) PubMed

 16193.

DnfA is identified as another protein that is endocytosed and recycled in the hyphal tip of A. nidulans. DnfA is a flippase (Type 4 P-Type ATPase) that was discovered to have roles in growth and conidiation.[DnfA] (Mus musculus) PubMed

 16194.

The purified Extracellular Serine Protease VpSP37 contains a Serine protease domain between residues 35 and 276 and a canonical Trypsin/Chimotrypsin 3D structure. [Extracellular Serine Protease] (Mus musculus) PubMed

 16195.

Study on genetic and biochemical characterization of phenol hydroxylase (Phe, NCgl2588) from Corynebacterium glutamicum that shares 31% identity in amino acids with phenol hydroxylase from yeast Trichosporon cutaneum [phenol hydroxylase] (Mus musculus) PubMed

 16196.

Interaction of frataxin withIscU of Fe-S clusters biogenesis pathway and its upregulation in AmpB resistant Leishmania donovani [frataxin][IscU] (Mus musculus) PubMed

 16197.

the first structure of a FadR homologue from mycobacterium is presented and the structure reveals DNA and ligand binding features of Fad35R.[Fad35R] (Mus musculus) PubMed

 16198.

cruzipain could be an important activator of latent TGF-beta and thereby trigger TGF-beta-mediated events crucial for the development of Chagas disease.[Cruzipain] (Mus musculus) PubMed

 16199.

In Bacillus anthracis, loss of hmgA, encoding homogentisate 1,2-dioxygenase, results in accumulation of a melanin-like pigment called pyomelanin. [Homogentisate 1,2-Dioxygenase] (Mus musculus) PubMed

 16200.

OsHKT1;1 has a role in controlling sodium concentration and preventing sodium toxicity in leaf blades and is regulated by the OsMYBc transcription factor.[OsMYBc] (Mus musculus) PubMed

 16201.

Maid is important regulator of hepatocarcinogenesis and aging [maid] (Mus musculus) PubMed

 16202.

PcFKH1 controls the biosynthesis of penicillin in Penicillium chrysogenum [PcFKH1] (Mus musculus) PubMed

 16203.

The thermal unfolding/refolding process of cold shock protein A characterized by circular dichroism, differential scanning calorimetry and NMR spectroscopy indicated that the refolding process was almost completely reversible. [cold shock protein A] (Mus musculus) PubMed

 16204.

PBP1/PBP2 are minimal requirement for peptidoglycan synthesis sufficient for S. aureus survival; deletion of other peptidoglycan synthesis components sacrifices virulence/antibiotic resistance. [PBP1; penicillin-binding protein 1; peptidyl transferase 1] (Mus musculus) PubMed

 16205.

ZmBDF could improve stress tolerance to drought and salt in maize. [BDF] (Mus musculus) PubMed

 16206.

findings show that the WOR1 5' UTR regulates the white-opaque phenotype by reducing translational efficiency of WOR1 [WOR1] (Mus musculus) PubMed

 16207.

Data suggest that microRNA-UL112-3p down-regulated human TLR2 (toll like receptor 2) and down-regulates TLR2-induced post-translational activation of human IRAK1 (interleukin 1 receptor associated kinase 1) signaling. [microRNA-UL112] (Mus musculus) PubMed

 16208.

Conserved B-cell epitope within S. dysgalactiae GapC could provide very valuable insights for vaccine design against S. dysgalactiae infection.[GapC] (Mus musculus) PubMed

 16209.

LdMAPK1 negatively regulates the expression of P-glycoprotein-type efflux pumps in the parasite; an increase in LdMAPK1 expression may result in increased antimony accumulation in the parasite, making it more vulnerable to the drug. [MAPK1] (Mus musculus) PubMed

 16210.

propose that residue His1001 is involved in the hemin-binding mechanism of the P. gingivalis rHA2 (recombinant hemagglutinin 2 domain (rHA2) of gingipain) and the peptide containing this residue, DHYAVMISK, may be an inhibitor of hemin binding [HA2} (Mus musculus) PubMed

 16211.

[NS1] - antagonizes mitochondrial antiviral signaling adaptor mediated apoptosis in H3N2 swine influenza virus infection (Mus musculus) PubMed

 16212.

Data suggest that enteropathogenic Escherichia coli down-regulates host immune response via NieA which suppresses macrophage inflammasome activity through targeting of NLRP3 (cryopyrin). [NleA; non-LEE-encoded effector A] (Mus musculus) PubMed

 16213.

The discovery that S. aureus LukAB provokes differential host responses in a manner dependent on the cellular contact site is critical for the development of anti-infective/anti-inflammatory therapies that target the NLRP3 inflammasome. (Mus musculus) PubMed

 16214.

Data suggest that enteropathogenic Escherichia coli down-regulates host immune response via NieA which suppresses macrophage inflammasome activity through targeting of NLRP3 (cryopyrin). [NleA; non-LEE-encoded effector A] (Mus musculus) PubMed

 16215.

Dengue RNA-dependent RNA polymerase specifically binds to the viral 5'-UTR with an apparent Kd of 53 nM. [RNA-dependent RNA polymerase] (Mus musculus) PubMed

 16216.

Results inferred that the V-region head of SspB recognizes an actinomyces polysaccharide ligand, so further characterizing a lectin-like coaggregation mechanism occurring between two important primary colonizers [SspB] (Mus musculus) PubMed

 16217.

Data suggest that human NCL (nucleolin) is re-localized during lytic KSHV (Kaposi sarcoma-associated herpesvirus) infection and protects human IL6 (interleukin-6) mRNA from SOX degradation in cytoplasm. [SOX; cytoplasmic mRNA-specific endonuclease] (Mus musculus) PubMed

 16218.

The majority of isolates from Ethiopia were mutant for the pfcrt 76 and wild-type for pfmdr-1 86. In contrast, the majority of Tanzanian samples were wild-type for both pfcrt and pfmdr-1 loci.[PfUBP-1] (Mus musculus) PubMed

 16219.

Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells [NPHP4] (Mus musculus) PubMed

 16220.

study characterized dynamic distribution of WapA ( wall-associated protein A)in single, dividing and long chains of cells; dynamic relocation of WapA through the cell cycle increases understanding of the mechanism of WapA in maintaining cell chain integrity and biofilm formation [WapA] (Mus musculus) PubMed

 16221.

The geometric and electronic structures of the biferrous active site in Escherichia coli bacterioferritin is studied using circular dichroism. [bacterioferritin] (Mus musculus) PubMed

 16222.

Leu135 and Tyr236 are required for RNA binding activity of CFIm25 in Entamoeba histolytica [CFIm25] (Mus musculus) PubMed

 16223.

Data suggest that PG0026/peptidase C25 functions as the C-terminal-domain signal peptidase in the type IX secretion system of Porphyromonas gingivalis W50 strain. [PG0026; peptidase C25; PorU] (Mus musculus) PubMed

 16224.

JHP0290 may affect H. pylori-induced gastric diseases via the regulation of gastric epithelial cell proliferation and anti-apoptotic pathways. [JHP0290] (Mus musculus) PubMed

 16225.

This study aims to (1) demonstrate the asymmetric oxidation activity of an HASApf expressed by bacteria, (2) characterize an HASApf-redoxin complex eluted from PP using the ESR and FTIR analyses. [HASApf] (Mus musculus) PubMed

 16226.

Expression and function analysis of two naturally truncated MyD88 variants in the Pacific oyster Crassostrea gigas [MyD88] (Mus musculus) PubMed

 16227.

SasG maintains a highly extended conformation in solution mediated through obligate folding cooperativity of the intrinsically disordered E domains that couple non-adjacent G5 domains thermodynamically. (Mus musculus) PubMed

 16228.

Data suggest that a single protein S-acyl transferase, PFA4, is responsible for palmitoylation of subset of cryptococcal proteins that are critical in pathogenesis/virulence of C. neoformans. [PFA4; palmitoyltransferase; protein S-acyl transferase 4] (Mus musculus) PubMed

 16229.

regulation of Crumbs alternative splicing by the Obelus helicase modulates epithelial polarity during development [obelus] (Mus musculus) PubMed

 16230.

[CsHMA3] and [CsMHA4] - molecular and biochemical properties suggest an important role in Cd and Pb detoxification and Zn homeostasis (Mus musculus) PubMed

 16231.

Unlike RgpA, which is VimA-dependent, the maturation/activation pathways for RgpB and Kgp are interdependent in the absence VimA.[RgpB, Kgp]. (Mus musculus) PubMed

 16232.

Tissue distribution of olive flounder VDAC2 and its expression in fish cell lines (Mus musculus) PubMed

 16233.

Polymorphisms and DNA methylation level in the CpG site of the GHR1 gene associated with mRNA expression, growth traits and hormone level of half-smooth tongue sole (Cynoglossus semilaevis)[GHR1] (Mus musculus) PubMed

 16234.

Aggregation of R. leguminosarum was achieved when the rapA1 gene expression was enhanced either in rhizobia or in the co-cultured modified strain E. coli pJN105TurboRapA1. (Mus musculus) PubMed

 16235.

Data suggest that, by targeting/repressing GRK2 (G-protein coupled receptor kinase 2), microRNA-K3 of Kaposi sarcoma-associated herpesvirus (KSHV) facilitates migration and invasion of vascular endothelial cells. [MIRNK3; microRNA-K3] (Mus musculus) PubMed

 16236.

The SecA from Escherichia coli forms active protein-conducting channels with injection of proteoliposomes, protein precursors, and ATP-Mg(2+). (Mus musculus) PubMed

 16237.

study drew attention to the credibility of the mecA gene and its usefulness in the detection of all MRSA strains without referring to the traditional methods. (Mus musculus) PubMed

 16238.

Data suggest that MCP14 is involved in multiple drug resistance exhibited by Trypanosoma brucei brucei; MCP14 appears to be involved with energy production and proline transport. (MCP14; mitochondrial carrier protein 14) (Mus musculus) PubMed

 16239.

Thermus thermophiles argonaute-mediated interference with plasmid DNA stimulates CRISPR adaptation.[Argonaute] (Mus musculus) PubMed

 16240.

The autotransporter BpaB contributes to the virulence of burkholderia mallei in an aerosol model of infection. [BpaB] (Mus musculus) PubMed

 16241.

Transcript quantification data as well as in situ and immunolocalization experiments demonstrated that at least two laccases (LACCASE5 and LACCASE6) are present in lignifying tissues.[LACCASE5] (Mus musculus) PubMed

 16242.

Conclude that differences in the electrostatic interactions at the binding interface between Ivy inhibitor Ivyp1 and distinct lysozymes determine the strength of this interaction. (Mus musculus) PubMed

 16243.

The noppera-bo gene from the silkworm Bombyx mori (nobo-Bm) is essential for ecdysteroid biosynthesis (Mus musculus) PubMed

 16244.

The study showed that the single gene apnI, encoding a putative transmembrane protein, was responsible for subtilomycin immunity (apnI). (Mus musculus) PubMed

 16245.

a three-tiered genome-wide screen was devised to identify additional Ypk1 substrates, which pinpointed both catalytic subunits of the ceramide synthase complex.[Ypk1, Lac1, Lag1] (Mus musculus) PubMed

 16246.

We propose that EcpR1 contributes to modulation of cell cycle regulation under detrimental conditions (Mus musculus) PubMed

 16247.

[Cs1,6RhaT] - isolation and functional characterization; encodes a branch-forming flavonoid glucose 1,6-rhamnosyltransferase, key enzyme directing biosynthesis flavanone rutinosides (Mus musculus) PubMed

 16248.

XopJ has protease activity to specifically degrade RPT6.[XopJ] (Mus musculus) PubMed

 16249.

The objective of this work was to functionally characterize the role of micro-RNA172 (miR172) and its conserved target APETALA2 (AP2) transcription factor in the common bean (Phaseolus vulgaris)-Rhizobium etli symbiosis.[microrna72c, AP2-1] (Mus musculus) PubMed

 16250.

TraeALDH7B1-5A is an important drought responsive gene for genetic transformation to improve drought tolerance in crops.[TraeALDH7B1-5A] (Mus musculus) PubMed

 16251.

OsKASI deficiency resulted in reduced fertility and a remarkable change in fatty acid (FA) composition and contents in roots and seeds.[KASI] (Mus musculus) PubMed

 16252.

the high-resolution structure of PfRh5, the protein from Plasmodium falciparum that forms a complex with other proteins to allow the parasite to bind to, and invade, red blood cells, is reported.[PfRh5] (Mus musculus) PubMed

 16253.

a drought-resistant gene TaSnRK2.7 in wheat species, was characterized.[TaSnRK2.7] (Mus musculus) PubMed

 16254.

OsDREB1A and OsDREB1B were targeted across several rice genotypes showing differential response to low temperature.[DREB1A, DREB1B] (Mus musculus) PubMed

 16255.

We discovered that bacterial cells control the spatio-temporal remodeling of microdomains by restricting the activation of FloT expression to stationary phase. (Mus musculus) PubMed

 16256.

MamA has remained remarkably constant throughout evolution with minimal change between different taxa despite sequence variations. (Mus musculus) PubMed

 16257.

Genetic analysis indicates that the ngp4c phenotype is controlled by a single recessive gene, tentatively named as NGP4c(t) and the NGP4c(t) gene was finally mapped to 81.7 kb region.[NGP4c(t)] (Mus musculus) PubMed

 16258.

BMR-6 not only affects the distribution of lignin but also the biosynthesis of lignin in sorghum.[BMR-6] (Mus musculus) PubMed

 16259.

Suggest that Smed-follistatin inhibits Smed-Activin-1/-2 proteins to trigger regeneration specifically following injuries involving tissue absence and identify a mechanism critical for regeneration initiation. (Mus musculus) PubMed

 16260.

The authors show that a Toxoplasma gondii Vps11 orthologue is essential for the biogenesis or proper subcellular localization of secretory organelle proteins.[Vps11] (Mus musculus) PubMed

 16261.

Acetylation of C21 Hydroxysteroids by the Bacterial Chloramphenicol Acetyltransferase I [CATI] (Mus musculus) PubMed

 16262.

"Bind and Crawl" Association Mechanism of Leishmania major Peroxidase and Cytochrome c Revealed by Brownian and Molecular Dynamics Simulations. (Mus musculus) PubMed

 16263.

Adenylylsulfate-ammonia adenylyltransferase activity is another inherent property of Fhit proteins. (Mus musculus) PubMed

 16264.

BAPKO_0422 is demonstrated to bind human factor H (fH) and therefore may contribute to immune evasion by inhibition of the complement response. (Mus musculus) PubMed

 16265.

CsCCL17 is a functional CC chemokine with the ability to recruit leukocytes and enhance host immune defense in a manner that requires the conserved SCCR motif.[CCL17] (Mus musculus) PubMed

 16266.

PXO_00987 is a putative acetyltransferase and is required for flagellin glycosylation, exopolysaccharide production, and biofilm formation.[PXO_00987] (Mus musculus) PubMed

 16267.

Extended spectrum beta-lactamase producing E. coli isolates were detected in 3/53 samples and carried the blaCTX-M-15 gene (one isolate also carried blaSHV-2). The remaining 6/53 samples had pAmpC positive isolates, which carried the blaCMY-2 gene.[blaSHV-2] (Mus musculus) PubMed

 16268.

Identification of zymocin residues required for early steps in toxin action.[k1ORF2 zymocin alphabeta subunits, and k1ORF4,zymocin gamma subunit] (Mus musculus) PubMed

 16269.

Crystal structures of Ape1 with a catalytic domain and a newly identified putative peptidoglycan-detection module are reported.[Ape1] (Mus musculus) PubMed

 16270.

Allophycocyanin B molecular conformation based on X-ray crystallography data. (Mus musculus) PubMed

 16271.

The AAC(6')-Ie enzyme is joined to APH(2'')-Ia by a short, predominantly rigid linker at the N-terminal end of a long alpha-helix.[AAC(6')-Ie-APH(2'')-Ia ] (Mus musculus) PubMed

 16272.

ThiT protein structure based on X-ray crystallography results.[ThiT] (Mus musculus) PubMed

 16273.

crystall structure of NS1 protein [NS1] (Mus musculus) PubMed

 16274.

Crystall EptC structure reveals the requirement for Thr266 as well as the nearby residues Asn308, Ser309, His358 and His440 for EptC activity. [EptC] (Mus musculus) PubMed

 16275.

The structure of a tetrameric alpha-carbonic anhydrase reveals a core formed around intermolecular disulfides that contribute to its thermostability.[alpha-carbonic anhydrase] (Mus musculus) PubMed

 16276.

our study has provided novel insights into the RIP2-mediated CARD-CARD interaction in zebrafish NOD1 and NOD2, which will be helpful to understand the molecular basis of the NOD1/2 signaling mechanism. (Mus musculus) PubMed

 16277.

These data suggest that TaCCoAOMT1 is an important Caffeoyl coenzyme A 3-O-methyltransferase for lignin biosynthesis that is critical for stem development, but not directly associated with lodging-resistant trait in wheat.[TaCCoAOMT1] (Mus musculus) PubMed

 16278.

The increased level of Bcl-2 caused by the decrease in miR-181c protected mitochondrial morphology from the tumour necrosis factor alpha-induced apoptosis.[miR-181c] (Mus musculus) PubMed

 16279.

The binding competition between VanU(G) and VanR(G) on the P(YG) resistance promoter allowed rheostatic activation of the resistance operon depending likely on the level of VanR(G) phosphorylation by the VanS(G) sensor. (Mus musculus) PubMed

 16280.

This study identifies a novel highly conserved parasite molecule, Pfvap1, that contributes to parasite virulence possibly by assisting PfEMP1 to establish functional adhesion at the host cell surface.[Pfvap1] (Mus musculus) PubMed

 16281.

This study identified a consensus DNA binding sequence for FleQ; a survey of Pseudomonas strains for FleQ regulated genes and their role in biofilms is reported. (Mus musculus) PubMed

 16282.

Molecular dynamics simulations indicate ChiA-R172A behaves like the wild type, but the dynamics of ChiA-T276A are greatly influenced by mutation, which is reflective of their influence on processivity. (Mus musculus) PubMed

 16283.

the biological importance of alpha-C-terminal domain is conserved in B. subtilis and E. coli, but that its specific roles have diversified between these two bacteria.[RpoA] (Mus musculus) PubMed

 16284.

Phosphoethanolamine transferase LptA in Haemophilus ducreyi modifies lipid A and contributes to human defensin resistance in vitro. [LptA] (Mus musculus) PubMed

 16285.

Study shows molecular cloning and characterization of CART1 Gene in chickens. CART1 is highly expressed in the anterior pituitary but less in the hypothalamus, and its expression is down-regulated by fasting implying that CART1 is a novel peptide hormone.[Cart2] (Mus musculus) PubMed

 16286.

The stabilized mutant FHbp thus has the potential to stabilize protective epitopes and increase the protective antibody responses to recombinant FHbp vaccines (Mus musculus) PubMed

 16287.

Results show that the hydrogenase small subunit HupS can be reduced by the Ru(II)-trisbipyridine (Ru(bpy)3) generated through flash photolysis: [HupS] (Mus musculus) PubMed

 16288.

The DTA crystal structure at 1.5 A resolution identified a metal-binding site close to the PLP-cofactor in its active site. Binding of the beta-hydroxy group of the substrate to the metal ion may activate this and facilitate deprotonation by His193. DTA. (Mus musculus) PubMed

 16289.

This report provides experimental evidence indicating the presence of a functional endosomal sorting complex required for transport component in Giardia lamblia by characterizing the putative Did2/Vps46 orthologues.[Did2, Vps46] (Mus musculus) PubMed

 16290.

Use cryo-electron microscopy to study how RF3 helps to release RF1 from the ribosome in bacteria. (Mus musculus) PubMed

 16291.

AaFz2 played important role in the regulation of TOR signaling (Mus musculus) PubMed

 16292.

Cloning and Characterization of an Enantioselective l-Menthyl Benzoate Hydrolase (MBH) from Acinetobacter sp. ECU2040 has been reported. [MBH] (Mus musculus) PubMed

 16293.

Conformational Plasticity of the POTRA 5 Domain in the Outer Membrane Protein Assembly Factor BamA is related to its interaction with BamD and possibly to substrate binding. [BamA] (Mus musculus) PubMed

 16294.

Tall fescue plants constitutively expressing vacuole- or apoplast-targeted ferulic acid esterase from Aspergillus niger were retransformed with a senescence-induced and apoplast-targeted beta-1,4 endo-xylanase from Trichoderma reesei.[beta-1,4 endoxylanase] (Mus musculus) PubMed

 16295.

Tall fescue plants constitutively expressing vacuole- or apoplast-targeted ferulic acid esterase from Aspergillus niger were retransformed with a senescence-induced and apoplast-targeted beta-1,4 endo-xylanase from Trichoderma reesei.[Ferulic acid esterase] (Mus musculus) PubMed

 16296.

SufC promotes S. Typhi coping oxidative stress and help S. Typhi survival in macrophages. [SufC] (Mus musculus) PubMed

 16297.

The findings indicate that defects in post-mitotic G1 nuclear formation caused by lack of Src1 promote repeated failed attempts to generate stable G1 nuclei. (Mus musculus) PubMed

 16298.

Embryonic Lethality of a Novel Red Egg Mutant Fuyin-lre of Silkworm [Fuyin] (Mus musculus) PubMed

 16299.

monovalent cation selectivity of beta-galactosidase [beta-galactosidase ] (Mus musculus) PubMed

 16300.

These data are consistent with a model in which MtNramp1 is the main transporter responsible for apoplastic iron uptake by rhizobia-infected cells in zone II.[Nramp1] (Mus musculus) PubMed

 16301.

The authors report that DcpA possesses both c-di-GMP synthesizing and degrading activities in heterologous and native genetic backgrounds, a binary capability that is unusual among GGDEF-EAL domain-containing proteins.[DcpA] (Mus musculus) PubMed

 16302.

During spermatogenesis TEP1 binds to and removes damaged cells through the same complement-like cascade that kills malaria parasites in the mosquito midgut. (Mus musculus) PubMed

 16303.

TaGW2-6a is associated with grain weight in wheat. (Mus musculus) PubMed

 16304.

This work shows that the ParB-parS chromosome segregation machinery also influences the DNA transformation competence development in Streptococcus pneumoniae.[ParB, parC] (Mus musculus) PubMed

 16305.

The BBR47_28440 gene (referred to as ddlR) encodes an MocR/GabR family transcriptional regulator consisting of an N-terminal helix-turn-helix DNA binding domain and a C-terminal aminotransferase-like domain. (ddlR) (Mus musculus) PubMed

 16306.

The atomistic-level details explored in this work will be highly useful for the design of non-resistant novel PfDHFR inhibitors as antimalarial agents (Mus musculus) PubMed

 16307.

A lytic polysaccharide monooxygenase LPMO10A from Bacillus thuringiensis has been cloned and characterized. [LPMO10A] (Mus musculus) PubMed

 16308.

Our data show that during evolution of the Helicobacter genus, acquisition of Hpn and Hpn-2 by gastric Helicobacter species constituted a decisive evolutionary event to allow Helicobacter to colonize the hostile gastric environment[Hpn] (Mus musculus) PubMed

 16309.

CotG has negative effects on spore germination and on assembly of outer coat proteins. Such negative action is seen only in mutants lacking CotH, suggesting an antagonistic effect of the proteins, with CotH counteracting the role of CotG. (CotG and CotH)) (Mus musculus) PubMed

 16310.

Taken together, this study provides evidence that Sac1, as a potential phosphatidylinositol phosphate phosphatase, is essential for actin organization, hyphal development, cell wall integrity and pathogenicity in Candida albicans. (Mus musculus) PubMed

 16311.

expressed and purified the N terminal domain of Fhb, a surface virulence protein that binds factor H (Fhb) (Mus musculus) PubMed

 16312.

this study reveals GH20C to be another tool that is unique in the arsenal of S. pneumoniae and that it may implement the effort of the bacterium to utilize and/or destroy the wide array of host glycans that it may encounter. (Mus musculus) PubMed

 16313.

PvETRAMP11.2 partially co-localized with PvEXP1 on the intracellular membranes of immature schizont.[PvETRAMP11.2, PVEXP1] (Mus musculus) PubMed

 16314.

In this study, we verified that cytoplasmic AfCpcB acts as a Gbeta-like protein ortholog and plays important roles in hyphal growth, conidiophore morphology, cell wall integrity, and virulence in Aspergillus fumigatus.[AfCpcB] (Mus musculus) PubMed

 16315.

Subtilin-like lantibiotics, such as entianin, ericin S, and subtilin, specifically activated SpaK in a comparable manner.[SpaK] (Mus musculus) PubMed

 16316.

These results indicate that PFR1, PFR2, and GP72 contribute to flagellar attachment to the cell body and motility of the parasites.[PFR1, PFR2] (Mus musculus) PubMed

 16317.

Sliding proficiency was transduced by the Spo0A-phosphorelay histidine kinases KinB and KinC.[KinB, KinC] (Mus musculus) PubMed

 16318.

Plasmodium falciparum and other apicomplexans possess a unique heterodimeric glutamyl-tRNA amidotransferase consisting of GatA and GatB subunits (GatAB)[GatA, GatB] (Mus musculus) PubMed

 16319.

Taking these results together, we identify Gaf1 as a novel target for TORC1 signaling and a step-like mechanism to modulate the nitrogen stress response.[TORC1, Gaf1] (Mus musculus) PubMed

 16320.

Pga1 activates mast cells and macrophages via host NFkB. [Pga1] (Mus musculus) PubMed

 16321.

The results suggest that the A/T polymorphisms could regulate CagA activity through interfering with host signaling pathways related to carcinogenesis (CagA). (Mus musculus) PubMed

 16322.

PhoU mutations inhibit mutagenic break repair in E coli. [PhoU] (Mus musculus) PubMed

 16323.

The axial ligation of the heme in ferric HmuT is probed by examination of wild-type HmuT and a series of conserved heme pocket residue mutants, H136A, Y235A, and M292A. (HmuT protein) (Mus musculus) PubMed

 16324.

We describe RING finger protein with microtubule-targeting domain 1 (RMT1), a functional RING E3 ligase that is likely involved in a salt tolerance mechanism. (RMT1) (Mus musculus) PubMed

 16325.

These results suggest that ZipA regulation of secondary metabolism is modified by oxidative stress pathways and provide insights into a possible role of ZipA in mediating secondary metabolite synthesis in Pestalotiopsis fici.[ZipA] (Mus musculus) PubMed

 16326.

TrgI is the toluene tolerance gene in Pseudomonas putida S12. [trgI] (Mus musculus) PubMed

 16327.

This study demonstrates the dissemination of cephalosporins resistant, integron borne blaPER-1 in hospital setting in this part of the country . (Mus musculus) PubMed

 16328.

Co-localization of Pi04089 and StKRBP1, and bimolecular fluorescence complementation between them, indicate they associate at nuclear speckles.[StKRBP1] (Mus musculus) PubMed

 16329.

Data indicate that the crystal structure of WbnH displays the typical fold of GT-B glycosyltransferases: [WbnH] (Mus musculus) PubMed

 16330.

Wheat NF-YA10-1 functions independently in salinity and drought stress. [NF-YA10-1] (Mus musculus) PubMed

 16331.

Structured and intrinsically disordered domains of NepR coordinately control multiple functions in the general stress response signaling pathway, including core protein partner switch interactions and pathway activation by phosphorylation.[NepR] (Mus musculus) PubMed

 16332.

The authors show here that the increase in ToxR production in response to asparagine, arginine, glutamate, and serine requires the Var/Csr global regulatory circuit.[ToxR, CsrA] (Mus musculus) PubMed

 16333.

[Urm1] Urm1 is homologous to the eukaryotic Urm1 Urmylated substrates are recognized and processed by the archaeal proteasome, by virtue of a direct interaction with the modifier. (Mus musculus) PubMed

 16334.

OsMADS1 has diversified regulatory functions in specifying rice floral organ and meristem identity.[OsMADS1] (Mus musculus) PubMed

 16335.

CEF1 belongs to the R2R3-MYB subfamily and it plays an important role in GA-regulating secondary cell wall synthesis. (CEF1/MYB103L) (Mus musculus) PubMed

 16336.

SAXS data suggest structural flexibility in EF hand domains indicative of conformational plasticity within TbbVSP1. (Mus musculus) PubMed

 16337.

Here, the authors report the discovery of a novel gene MCU1 essential for N-acetylglucosamine utilization.[MCU1] (Mus musculus) PubMed

 16338.

Altogether, these results establish a role for platelet activating factor receptor in mediating ExoU-induced cerebral microvascular failure in a murine model of sepsis.[ExoU] (Mus musculus) PubMed

 16339.

a novel S. pyogenes enzyme with 5'-nucleotidase activity and immune evasion properties (Mus musculus) PubMed

 16340.

Mycobacterium smegmatis has a third enzyme, CYP125A4, that also oxidizes cholesterol, although it has a much higher activity for the oxidation of 7alpha-hydroxycholesterol. (CYP125A4) (Mus musculus) PubMed

 16341.

we identified a functionally uncharacterized protein, RqlI, which promotes extraintestinal pathogenic Escherichia coli survival within diverse host environments (Mus musculus) PubMed

 16342.

The X-ray structure of protease-cleaved Escherichia coli alpha-2-macroglobulin is described, which reveals a putative mechanism of activation and conformational change essential for protease inhibition. [alpha-2-macroglobulin] (Mus musculus) PubMed

 16343.

Three crystal structures of galactitol 1-phosphate by galactitol-1-phosphate 5-dehydrogenase (GPDH) are reported: the open state of GPDH with Zn(2+) in the catalytic site and the closed state in complex with the polyols Tris and glycerol. [GPDH] (Mus musculus) PubMed

 16344.

The dehydration-triggered molecular reshaping reveals an inherent molecular flexibility that possibly informs on the function of immediate-early 1 protein namely on its binding to target proteins from the host cell. [immediate-early 1 protein] (Mus musculus) PubMed

 16345.

Study shows that purified Dmc1 forms presynaptic filaments and catalyzes ATP-dependent homologous DNA pairing and DNA strand exchange over at least several thousand base pairs; DNA pairing and strand exchange activities are enhanced by the presence of calcium and the meiosis-specific recombination accessory factor, Hop2-Mnd1. (Mus musculus) PubMed

 16346.

The crystal structure of the sortase D enzyme from Clostridium perfringens was determined at 1.99 A resolution. [sortase D] (Mus musculus) PubMed

 16347.

The results suggest that AoMad1 plays an important role in life style switching in Arthrobotrys oligospora.[AoMad1] (Mus musculus) PubMed

 16348.

BcMF26a/b can participate in the construction of pollen wall by modulating intine information [MF26a; MF26b] (Mus musculus) PubMed

 16349.

the talpid(2) model was uded to examine the cellular basis for the oral-facial phenotypes present in oral-facial-digital syndrome.[talpid2] (Mus musculus) PubMed

 16350.

TACC1 and TACC3 are each required for maintaining normal microtubule growth speed in Xenopus [TACC1] (Mus musculus) PubMed

 16351.

these results uncover a novel function of TbSAS-4 in regulating the length of the FAZ filament to control basal body positioning and life cycle transitions in T. brucei. (Mus musculus) PubMed

 16352.

The structure of VanT showed significant similarity to type III pyridoxal 5'-phosphate (PLP)-dependent alanine racemases, which are essential for peptidoglycan synthesis.[VanT] (Mus musculus) PubMed

 16353.

Pex11p plays role in peroxisome assembly.[Pex11p] (Mus musculus) PubMed

 16354.

The authors identified a new viral protein, PB2-S1, encoded by a novel spliced mRNA in which the region corresponding to nucleotides 1513 to 1894 of the PB2 mRNA is deleted.[PB2-S1] (Mus musculus) PubMed

 16355.

It is particularly noteworthy that feline APOBEC3Z3 haplotype V is resistant to feline immunodeficiency virus Vif-mediated degradation and still inhibits vif-proficient viral infection.[Vif] (Mus musculus) PubMed

 16356.

The primary function of protein VI is to mediate interactions hexon, driving particle assembly. Once particles are assembled, the N-terminal 33 residues are released allowing it to lyse the endosome during cell infection.[protein VI] (Mus musculus) PubMed

 16357.

1-Cys peroxiredoxin gene coded a protein of 213 amino acids with the molecular mass of 24.85 kDa. [1-Cys peroxiredoxin] (Mus musculus) PubMed

 16358.

The authors describe a novel Imi1 protein of Saccharomyces cerevisiae affecting mitochondrial integrity and involved in controlling glutathione level.[Imi1] (Mus musculus) PubMed

 16359.

Exposure of parasites to a histone methyltransferase small-molecule inhibitor also induces upregulation of var2csa. [var2csa] (Mus musculus) PubMed

 16360.

These observations suggest wide-spread conservation of the roles of casein kinase 1 and Rec11 in ensuring proper meiotic chromosome segregation and sexual reproduction. [Casein Kinase 1] (Mus musculus) PubMed

 16361.

R1-mediated immunity is activated inside the nucleus with AVR1 in close proximity and suggest that nucleocytoplasmic transport of R1 and AVR1 is tightly regulated.[R1, AVR1] (Mus musculus) PubMed

 16362.

Acetoacetyl-CoA thiolase is a dual-localizing enzyme that localizes to peroxisomes, mitochondria and the cytosol using protein sorting signals and the alternative utilization of start codons.[Acetoacetyl-CoA thiolase] (Mus musculus) PubMed

 16363.

P55 efflux pump functions in maintaining general metabolism or as a subunit of the Mce4 transport apparatus (catalyzing its assembly or providing cell wall integrity) to allow more efficient cholesterol uptake[p55] (Mus musculus) PubMed

 16364.

The structure of the lipid-modified azurin from Neisseria gonorrhoeae, the electron donor of cytochrome c peroxidase, has been solved in solution (lipid-modified azurin). (Mus musculus) PubMed

 16365.

The coupling step in the Na+-translocating NADH:quinone oxidoreductase subunit NqrF has been identified. [NqrF] (Mus musculus) PubMed

 16366.

TaPP2C1 confers salt resistance through activating the antioxidant system and abscissic acid-independent gene transcription process.[TaPP2C1] (Mus musculus) PubMed

 16367.

Data suggest refolding of Rubisco is assisted by chloroplast chaperonins and co-chaperonins in asymmetric functional cooperation; proteins from various species and of various sizes are complementary. [Rru, ribulose bisphosphate carboxylase oxygenase] (Mus musculus) PubMed

 16368.

association of RbmA with the matrix reinforces the biofilm structure and leads to limited proteolysis of RbmA to RbmA* [RbmA] (Mus musculus) PubMed

 16369.

the SufB intein of Mycobacterium tuberculosis has a role as a sensor for oxidative and nitrosative stresses [SufB] (Mus musculus) PubMed

 16370.

The 2.75 A resolution structure of SPECT1 reveals that the protein forms a four-helix bundle, with the rare feature of having all of these helices in parallel or antiparallel alignment.[SPECT1] (Mus musculus) PubMed

 16371.

Spra, Sprb and SpsM genes are required for spore envelope maturation in Bacillus subtilis and prophage excision.spsM is essential for the addition of polysaccharides to the spore envelope.{SPRa] [Sprb] [SpsM] (Mus musculus) PubMed

 16372.

The Zygosaccharomyces rouxii STL genes are not repressed by glucose, but their expression and activity are downregulated by fructose and upregulated by non-fermentable carbon sources, with ZrSTL1 being more influenced than ZrSTL2.[STL1, STL2] (Mus musculus) PubMed

 16373.

EzeT consists of two domains combining toxin and cis-acting antitoxin functionalities in a single polypeptide chain.[EzeT] (Mus musculus) PubMed

 16374.

Data suggest that tyrosine 172 plays key role in substrate binding in NDCR, a novel enzyme expressed in liver of chickens with fatty liver (thyroidectomized as model of hypothyroidism symptoms). [NDCR, NAD(P)H-dependent carbonyl reductase] (Mus musculus) PubMed

 16375.

The study shows that Listeriolysin O affects the permeability of Caco-2 monolayer in a Ca2+ independent manner. [Listeriolysin O] (Mus musculus) PubMed

 16376.

TCLP 1 is involved in the uptake of extracellular macromolecules required for nutrition and hence in T. cruzi growth. [TCLP 1] (Mus musculus) PubMed

 16377.

Data suggest that conservation of threonine at position 75 of TIM relates to temperature stability of enzyme activity; restriction to glutamine/glutamic acid at position 64 relates to dimer stability. [TIM, triosephosphate isomerase] (Mus musculus) PubMed

 16378.

Data suggest dcsD (O-acetylserine sulfhydrylase) catalyzes an additional reaction; dcsD uses O-acetyl-L-serine plus hydroxyurea to form O-ureido-L-serine as biosynthetic intermediate in formation of D-cycloserine. [dcsD, acetylserine sulfhydrylase] (Mus musculus) PubMed

 16379.

A compensatory upregulation of the potassium channels K2P3.1 and KV1.3 seems to counterbalance the deletion of K2P5.1.[K2P5.1, K2P3.1] (Mus musculus) PubMed

 16380.

the rhizobial waaL gene is responsible for the establishment of a symbiotic relationship between soybean and B. japonicum.[waaL] (Mus musculus) PubMed

 16381.

MorC protein plays role in cell membrane protein composition. [MorC] (Mus musculus) PubMed

 16382.

[WKS1] - phosphorylation of thylakoid-associated ascorbate peroxidase reduces the ability of the cells to detoxify reactive oxygen species and contributes to cell death (Mus musculus) PubMed

 16383.

These results suggest a novel and specific role for PspA in modulating immune responses against S. pneumoniae by regulating PD-L1 expression. (Mus musculus) PubMed

 16384.

Findings implicate Aeromonas hydrophila nuclease in A. hydrophila virulence, with important functions in evading innate immune defenses.[nuclease] (Mus musculus) PubMed

 16385.

crip2 could be detected in the cardiovascular system, the brain and the neural tube while crip3 was expressed in the cranial ganglions and the heart. [crip2] [crip3] (Mus musculus) PubMed

 16386.

The role of different czcRS genes in metal resistance and the cross-link between czcRS and czcCBA in Pseudomonas putida X4 were studied to advance understanding of the mechanisms by which P. putida copes with metal stress.[CzcRS1, CzcRS2] (Mus musculus) PubMed

 16387.

Plasmodium falciparum profilin consists of two independently folding units and suggest that evolution via fusion of two ancestral genes has led to the present profilin fold.[profilin] (Mus musculus) PubMed

 16388.

RbgA functions to properly position L6 protein on the ribosome, prior to the incorporation of L16 and other late assembly proteins.[rbga] [L6 protein] (Mus musculus) PubMed

 16389.

These results indicate that O-phospho-l-serine sulfhydrylase (OPSS) is more superior to OASS-B for the industrial production of l-cysteine and unnatural amino acids that are useful pharmaceuticals in the presence of organic solvent. (Mus musculus) PubMed

 16390.

MHZ4 acts downstream of ethylene receptors in regulating root growth but upstream of OsEIN2 in regulating coleoptile elongation (MHZ4). (Mus musculus) PubMed

 16391.

The authors demonstrate that protein tyrosine phosphatase possesses dual phosphatase specificity for Tyr- and Ser/Thr-phosphorylated bacterial proteins.[protein tyrosine phosphatase] (Mus musculus) PubMed

 16392.

RAF2, RAF1 and BSD2 form transient complexes with the Rubisco small subunit, which in turn assembles with the large subunit.[RAF2] (Mus musculus) PubMed

 16393.

Identification of an NrtR family transcription factor (BT0354 in B. thetaiotaomicron, BtAraR) as a novel regulator controlling the arabinose utilization genes (BtAraR). (Mus musculus) PubMed

 16394.

The authors report the identification of McpG as a specific GABA chemoreceptor in non-pathogenic Pseudomonas putida KT2440.[McpG] (Mus musculus) PubMed

 16395.

The polycomb group gene EMF2B is essential for maintenance of floral meristem determinacy in rice.[EMF2B] (Mus musculus) PubMed

 16396.

The present results show that SCCmec type V MRSA has been on the rise, and genotypic markers such as pvl gene detection used for the differentiation of these clinically distinct isolates of MRSA may not be reliable. (Mus musculus) PubMed

 16397.

a hybrid crystal structure of Mycobacterium smegmatis mycocerosic acid synthase based on structures of its condensing and modifying regions [Mycocerosic acid synthase] (Mus musculus) PubMed

 16398.

Both ToxA and ToxB together are required to cause acute hepatopancreatic necrosis disease. [ToxA] [ToxB] (Mus musculus) PubMed

 16399.

Taken together, our findings suggest that inhibiting SpoIIQ, SpoIIIAA, or SpoIIIAH function could prevent the formation of infectious C. difficile spores and thus disease transmission. (Mus musculus) PubMed

 16400.

oxidation of EF-G might provide a regulatory mechanism for transient and reversible suppression of translation in E. coli under oxidative stress.[EF-G] (Mus musculus) PubMed

 16401.

The main transporter of nitrate, NrtA, proved to be more sensitive to chlorate than the minor transporter, NrtB.[NrtA, NrtB] (Mus musculus) PubMed

 16402.

Data indicte that CsWAX2 gene is highly expressed in the epidermis, where waxes are synthesized: [CsWAX2; WAX2] (Mus musculus) PubMed

 16403.

HAD1 dephosphorylates a variety of sugar phosphates, including glycolytic intermediates.HAD1 regulates the methylerythritol phosphate pathway.[HAD1] (Mus musculus) PubMed

 16404.

Rv1357c gene affects pellicle production and resistance to nitrosative stress in M. bovis. [Rv1357c] (Mus musculus) PubMed

 16405.

[HAC-1] - involved in the unfolded protein response and necessary for growth on cellulose (Mus musculus) PubMed

 16406.

Crystal Structure of Hcp from Acinetobacter baumannii [Hcp] (Mus musculus) PubMed

 16407.

Molecular structure of the class D beta-lactamse BPu1 reveals a unique substrate-binding mode. [Bpu1] (Mus musculus) PubMed

 16408.

Demonstrated the role of the transcriptional regulator FcsR, present upstream of the fcs operon, as a transcriptional activator of the fcs operon.[FcsR] (Mus musculus) PubMed

 16409.

study describes the purification and substrate specificity of the putative Tagatose-1-Phosphate Kinase (TagK) from B. licheniformis[TagK] (Mus musculus) PubMed

 16410.

[TbKIFC1] Trypanolysis by APOL1 is linked to apoptosis-like mitochondrial membrane permabilization occurring together with TbKIFC1-mediated transport of APOL1 from endolysosomal membranes to the mitochondrion. (Mus musculus) PubMed

 16411.

the role of cytoplasmic helices in the pentamer formation of Escherichia coli MscL, was investigated.[MscL] (Mus musculus) PubMed

 16412.

There are two SAPP2 gene homologs present in Candida parapsilosis genome.[SAPP2] (Mus musculus) PubMed

 16413.

ARC is Mg(+2)-dependent ATPase. [ARC] (Mus musculus) PubMed

 16414.

Thus, M2 proton channel activity plays a role in blocking the fusion of autophagosomes with lysosomes, which might be a key mechanism for arresting autophagy.[M2] (Mus musculus) PubMed

 16415.

These data suggest that influenza A virus M2 ectodomain can adopt at least two conformations that can elicit protective antibodies. (Mus musculus) PubMed

 16416.

A proportion of the Puf3 mRNA network is differentially expressed in biofilms, and by using a mutant in the mRNA deadenylase CCR4 we show that posttranscriptional regulation is important for mitochondrial regulation in biofilms (Mus musculus) PubMed

 16417.

Functional characterization of the T. gondii aspartyl protease 5 (ASP5) (Mus musculus) PubMed

 16418.

Novel pppGpp binding site at the C-terminal region of the Rel enzyme [Rel] (Mus musculus) PubMed

 16419.

Study shows that STAT3 rs744166 polymorphism and infection with helicobacter pylori with CagA possessing higher number of EPIYA-C segments are independent risk factors for gastric cancer. [cagA] (Mus musculus) PubMed

 16420.

Data suggest that two loops (loop 7 and loop 8) are responsible for substrate recognition in GH5, glycoside hydrolase family 5, endo-beta-1,4-mannanase. [GH5, endo-beta-1,4-mannanase] (Mus musculus) PubMed

 16421.

OsI-BAK1 is associated with the developmental processes of rice grain filling and leaf cell including the bulliform cells. (Mus musculus) PubMed

 16422.

The authors revealed that the two homologs of Paracoccus denitrificans BioR are functional repressors for biotin metabolism.[BioR1, BioR2] (Mus musculus) PubMed

 16423.

These results are also consistent with our previous kinetic analysis of OmpA self-association that revealed a nucleated growth polymerization mechanism, which is frequently observed in amyloid formation. [OmpA] (Mus musculus) PubMed

 16424.

HmuY is an important virulence factor of P. gingivalis for infection of macrophages in a heme-limited host environment. [HmuY] (Mus musculus) PubMed

 16425.

These results revealed a crucial role of PGI1 in coordination of the production of virulence factors, cell wall integrity and stress response in Cryptococcus neoformans.[PGI1] (Mus musculus) PubMed

 16426.

[Mirn34, Mirn449] miR-34/449 promote the assembly of an apical actin network, required for proper basal bodies anchoring during multiciliogenesis. (Mus musculus) PubMed

 16427.

[DNAK protein, e. coli strain bb 1553] Findings provide evidence of an unexpected dichotomic allostery mechanism in Hsp70 chaperones and provide the basis for a comprehensive mechanical model of allostery in Hsp70s. (Mus musculus) PubMed

 16428.

MAPKKK$ is eliciting accumulation of reactive oxygen species and hypersensitive response-like cell death. [MAPKKK4] (Mus musculus) PubMed

 16429.

two genes, hereafter named mmcA and mmcB, are involved in the defense against DNA damage caused by mitomycin C.[mmcA, mmcB] (Mus musculus) PubMed

 16430.

Kre (YkyB) controls the bimodal regulation of ComK.[Comk] [Kre] (Mus musculus) PubMed

 16431.

Lkh1 serves in some aspect of cell cycle regulation after DNA damage or replication stress and that it also contributes to proper chromosome segregation in meiosis.[LAMMER kinase] (Mus musculus) PubMed

 16432.

Furthermore, deletion of CaRCH1 suppresses the defect in hyphal development due to the deletion of CaCCH1 or CaECM7, and increases the virulence of cells lacking any of the HACS components.[CaRCH1, CaCCH1, CaECM7[ (Mus musculus) PubMed

 16433.

Replacement of two amino acids of 9R-dioxygenase-allene oxide synthase of Aspergillus niger inverts the chirality of the hydroperoxide and the allene oxide. [Allene oxide synthase] (Mus musculus) PubMed

 16434.

Analysis of the metabolism, X-ray crystal structures, and molecular docking simulations suggests that P450 BM3 activity toward BHTOOH and BMPOOH is mediated through substrate recognition by T268 and F87, and the active site cavity volume (Mus musculus) PubMed

 16435.

When bound to its specific target DNA sequences, SlmA reduces the lifetime of the FtsZ protofilaments in solution and of the FtsZ bundles when located inside permeable giant vesicles. [SlmA, FtsZ] (Mus musculus) PubMed

 16436.

study brings the first structural characterization, at the residue level, of yeast IF1 in its dimeric form[if1] (Mus musculus) PubMed

 16437.

a single microRNA, that is, miR-27 or miR-125, can selectively upregulate and downregulate discrete number of target mRNAs in a cell-type specific manner.[miR-27] (Mus musculus) PubMed

 16438.

This study used electron microscopy and two-dimensional class averaging to demonstrate that INO80-C and SWR-C have similar overall architectures.[INO80-C; SWR-C] (Mus musculus) PubMed

 16439.

The functional role of hyaluronate lyase R462 was proposed to facilitate the formation of initial enzyme-substrate complex, but not in the subsequent catalytic degradation reaction (hyaluronate lyase). (Mus musculus) PubMed

 16440.

CdiI protein only protects target bacteria from its cognate CdiA-CT toxin. CDIL immunity protein forms forms complex with CDIA protein. [cdia] [cdil] (Mus musculus) PubMed

 16441.

The Mex67p functions as the principal mRNP export receptor in budding yeast. In a mex67-5 mutant, delayed cytoplasmic release from NPCs and retrograde transport of mRNPs was observed. (Mus musculus) PubMed

 16442.

CdiI protein only protects target bacteria from its cognate CdiA-CT toxin. CDIL immunity protein forms forms complex with CDIA protein. [cdia] [cdil] (Mus musculus) PubMed

 16443.

KfoC has broad donor substrate specificity and acceptor promiscuity, making it an attractive tool enzyme for use in structurally-defined chimeric glycosaminoglycan oligosaccharide synthesis in vitro (Mus musculus) PubMed

 16444.

These results suggest that GF14b positively regulates panicle blast resistance but negatively regulates leaf blast resistance, and that GF14b-mediated disease resistance is associated with the jasmonic acid and salicylic acid dependent pathway.[GF14b] (Mus musculus) PubMed

 16445.

p17 nuclear localization facilitates the induction of autophagy and is correlated with an increase in virus production. (Mus musculus) PubMed

 16446.

CaGdt1 genetically interacts with the plasma membrane calcium channel, CaCch1/CaMid1, in the response to cold, endoplasmic reticulum stresses, antifungal drug challenge as well as in filamentation and virulence.[CaGdt1, CaCch1, CaMid1] (Mus musculus) PubMed

 16447.

This study showed that the naive follicular B-cell pool is enriched for cells expressing prototypic antinuclear antibody heavy chains in mice in a non-autoimmune background with a broad antibody repertoire. (Mus musculus) PubMed

 16448.

MCPIP1 is the target of mmu-miR-27-5p.[miR 27a] (Mus musculus) PubMed

 16449.

We report the identification of a novel sRNA that we designate PapR (P-fimbriae regulator) and elaborate on this discovery by demonstrating a role for PapR in regulation of P-fimbriae-a Uropathogenic Escherichia coli surface virulence factor[papr] (Mus musculus) PubMed

 16450.

results show that immunomodulation by HTLV-1 bZIP factor is implicated in both inflammation and oncogenesis (Mus musculus) PubMed

 16451.

These results suggest that FCaBP possesses two distinct Ca(2+)-dependent interactions-one involving a Ca(2+)-induced change in conformation and another perhaps involving binding partner association.[FCaBP] (Mus musculus) PubMed

 16452.

Studies revealed that a simultaneous presence of both the genes fhs and purT confers growth disadvantage compared to when present in single [fhs] (Mus musculus) PubMed

 16453.

AsnC protein is involved in the regulation of nuclease colicins.IscR is not involved in the regulation of nuclease colicins.AsnC is a key controller of the temporal induction of the DNA degrading colicin E8 gene (cea8), after DNA damage.[cea8][iscr][asnc] (Mus musculus) PubMed

 16454.

Zip1 promotes crossover during meiosis.Zip1 provides partial function at centromeres.[Zip1] (Mus musculus) PubMed

 16455.

Phytochrome B Mediates the Regulation of Chlorophyll Biosynthesis through Transcriptional Regulation of ChlH and GUN4 in Rice Seedlings. (Mus musculus) PubMed

 16456.

The authors find that conditional knockdown of TgFBP2 results in complete loss of intracellular growth in vitro under glucose-replete conditions and loss of acute virulence in mice.[TgFBP2] (Mus musculus) PubMed

 16457.

the increased absorption cross-section from the IsiA proteins translates directly to an enhanced rate of electron transfer through Photosystem I [IsiA] (Mus musculus) PubMed

 16458.

Site-Directed Mutagenesis of a Hyperthermophilic Endoglucanase Cel12B from Thermotoga maritima Based on Rational Design. (Mus musculus) PubMed

 16459.

the roles of conserved residues in uridyltransferase domain of Escherichia coli K12 GlmU [GlmU] (Mus musculus) PubMed

 16460.

We identify two specific histone deacetylases , Hos2 and Clr3, that are required for the virulence of the corn smut fungus, Ustilago maydis (Mus musculus) PubMed

 16461.

CeOCT-1 related members might be key transporters to facilitate entry of anthracyclines into human cells.[OCT-1] (Mus musculus) PubMed

 16462.

disruption of Holliday junction resolvase Mus81-Mms4 as the mutation responsible for DNA repair phenotypes currently ascribed to pby1.[pby1, Mus81, Mms4] (Mus musculus) PubMed

 16463.

The Bordetella secreted regulator BspR is translocated into the nucleus of host cells via its N-terminal moiety. [BspR] (Mus musculus) PubMed

 16464.

LepB promote the association of the central domain of colicin D with the inner membrane and translocation of the toxic tRNase domain into the cytoplasm.[colicin D] (Mus musculus) PubMed

 16465.

BAFF is an immunostimulator that significantly contributes to the innate antibacterial immune response and vaccine-induced adaptive immune response. [BAFF] (Mus musculus) PubMed

 16466.

The results suggest that Brassica napus SGS3 selectively inhibits Cucumber mosaic virus accumulation but promotes Oilseed rape mosaic virus and Turnip mosaic virus accumulation.[SGS3] (Mus musculus) PubMed

 16467.

We propose that Cwf16p/NTC participates in the early recognition of the branch and 3' splice sites and cooperates with the SF1-U2AF59-U2AF23 complex to maintain ordered exon joining (Mus musculus) PubMed

 16468.

The C-terminal tail portion of astexin-2 and astexin-3 is dispensable with regards to AtxE2 activity. [AtxE2] (Mus musculus) PubMed

 16469.

The combined results suggest that AnoIR is a quorum-sensing system that plays important roles in the biofilm formation and motility of Acinetobacter nosocomialis, and virstatin is an inhibitor of the expression of anoR.[AnoIR] (Mus musculus) PubMed

 16470.

The X-ray crystallographic structure of the dimeric alpha-carbonic anhydrase shows that it has a highly conserved yet compact structure compared with other alpha-carbonic anhydrases. [alpha-carbonic anhydrase] (Mus musculus) PubMed

 16471.

The structure of histidyl-tRNA synthetase is reported. A total of 15 fragments were identified, all bound to the same site on the protein, revealing a fragment-binding hotspot adjacent to the ATP-binding pocket. [histidyl-tRNA synthetase] (Mus musculus) PubMed

 16472.

Here, the crystal structure of Sld7 in complex with Sld3 is presented. Sld7 comprises two structural domains. [Zld7, Zld3] (Mus musculus) PubMed

 16473.

The crystal structure of shikimate kinase in complex with the substrate shikimate was determined to 1.91 A resolution and the enzyme kinetics were characterized. [shikimate kinase] (Mus musculus) PubMed

 16474.

The recombinant production of a soluble, self-complemented construct of the LpfD protein of E. coli LF82 is reported and it is demonstrated that it forms the adhesive tip subunit of long polar fimbriae. [LpfD] (Mus musculus) PubMed

 16475.

An N-terminal region of CTMyb1 protein is involved in its intracellular localization and activation of a gibberellin-inducible proteinase gene in germinated rice seeds.[CTMyb1] (Mus musculus) PubMed

 16476.

WD40D functions as a positive regulator of plant responses to salt stress and osmotic stress.[WD40D] (Mus musculus) PubMed

 16477.

diverse genetic combinations of Hd1, Hd2, Hd4, and Hd5 determined the different distribution of rice varieties in this northernmost province of China.[Hd2, Hd4] (Mus musculus) PubMed

 16478.

Analysis of the catabolic reaction products of PcaHG, PcaB, and PcaL in the beta-ketoadipate pathway. [PcaHG] [PcaB] [PcaL] (Mus musculus) PubMed

 16479.

The authors show that Murine cytomegalovirus m142 and m143 knockout mutants attain organ titers equivalent to those attained by wild-type virus in Pkr knockout mice.[m142, m143] (Mus musculus) PubMed

 16480.

These data points to a general requirement for AS2 repression in meristematic regions to allow cell proliferation.[AS2, WOX1] (Mus musculus) PubMed

 16481.

This analysis provides insights in the structure-function relationships of the OGT Alkylated DNA-protein alkyltransferase protein before, during and after DNA repair, suggesting a molecular basis for DNA recognition, catalytic activity and protein post-reaction fate (OGT). (Mus musculus) PubMed

 16482.

Crystal structure of the full length SelB clarified how the N- and C-terminal halves, which bind Sec-tRNASec and the SECIS RNA, respectively, are connected (SelB). (Mus musculus) PubMed

 16483.

an atypical active site of an l-aspartate/glutamate-specific racemase from Escherichia coli [L-DER] (Mus musculus) PubMed

 16484.

Functionally distinct cytochrome c peroxidases from Shewanella oneidensis and Nitrosomonas europaea proceed through a common (Electro)catalytic intermediate. [cytochrome c peroxidase] (Mus musculus) PubMed

 16485.

Functionally distinct cytochrome c peroxidases from Shewanella oneidensis and Nitrosomonas europaea proceed through a common (Electro)catalytic intermediate. [cytochrome c peroxidase] (Mus musculus) PubMed

 16486.

The crystal structure of c4763, a uropathogenic Escherichia coli-specific protein that might be involved in the utilization of urea, has been resolved. [c4763] (Mus musculus) PubMed

 16487.

The periplasmic siderophore/iron binding protein VatD from Vibrio vulnificus M2799 has been expressed, purified, and crystallized. [VatD] (Mus musculus) PubMed

 16488.

The structure of a putative carbohydrate-binding module from the Ruminococcus flavefaciens FD-1 endoglucanase Cel5A has been resolved. [Cel5A] (Mus musculus) PubMed

 16489.

Staphylococcus aureus SarV exists as a homodimer in solution. [SarV] (Mus musculus) PubMed

 16490.

The crystal structure of aspartate racemase has been resolved. [Aspartate racemase] (Mus musculus) PubMed

 16491.

The structure of the response regulator ChrA in the haem-sensing two-component system of Corynebacterium diphtheria has been resolved. [ChrA] (Mus musculus) PubMed

 16492.

The crystal structure of a FAD-dependent halogenase from Streptomyces sp. JCM9888 has been resolved. (Mus musculus) PubMed

 16493.

Crystallographic analysis of archaeal ribosomal protein L11 has been presented. [L11] (Mus musculus) PubMed

 16494.

Data suggest that lysine-56 of H3 is associated with nucleosome positioning suggested that this lysine residue and its acetylation contribute to chromatin assembly/disassembly, nucleosome mobility, and transcription activation. [histone H3] (Mus musculus) PubMed

 16495.

Phormidium phycoerythrin forms hexamers in crystals. [Phycoerythrin] (Mus musculus) PubMed

 16496.

rice OsRacGEF1 forms homodimers, and heterodimers with OsRacGEF2, at the plasma membrane (PM) and the endoplasmic reticulum (ER).[OsGEF1, OsGEF2] (Mus musculus) PubMed

 16497.

an increase in rice plant height caused by overexpression of a gene encoding a cytochrome P450 enzyme, CYP94C2b, is reported.[CYP94C2b] (Mus musculus) PubMed

 16498.

The crystal structure of ectoine synthase (ectC) from the cold-adapted marine bacterium Sphingopyxis alaskensis has been resolved. [ectC] (Mus musculus) PubMed

 16499.

The crystal structure of FAD-dependent glucose dehydrogenase (FAD-GDH) has been resolved. [FAD-GDH] (Mus musculus) PubMed

 16500.

Arr1 protein, mouse: Based on the opposite visual phenotypes in an all-cone retina in the Nrl-/-Arr1-/- and Nrl-/-Arr4-/- mice, we conclude that ARR1 and ARR4 perform unique modulatory roles in cone photoreceptors. (Mus musculus) PubMed

 16501.

Spy rapidly associates with its substrate, immunity protein 7 (Im7), thereby eliminating Im7's potential for aggregation.[immunity protein 7] (Mus musculus) PubMed

 16502.

bacterial homologue of the human iron exporter ferroportin [ferroportin] (Mus musculus) PubMed

 16503.

NMR data demonstrating structural and dynamic coupling between the selectivity filter and intracellular constriction point in the bacterial nonselective cation channel, NaK, is reported.[NaK] (Mus musculus) PubMed

 16504.

Data suggest that ClpS2 exhibits substrate specificity toward N-terminal leucine; turnover of ClpS2 substrates appears vital for cell viability. [ClpS2; Clp S2 aminopeptidase] (Mus musculus) PubMed

 16505.

crystal structure of ZapC from Escherichia coli [ZapC] (Mus musculus) PubMed

 16506.

multiconfigurational quantum chemistry is used to compare the isomerization mechanisms of the sensory rhodopsin from the cyanobacterium Anabaena PCC 7120 (ASR) and of the bovine rhodopsin (Rh).[ASR] (Mus musculus) PubMed

 16507.

L1 loop of EcfS acts as a gate in the substrate binding and release [EcfS] (Mus musculus) PubMed

 16508.

structure and function of beta-1,2-mannobiose phosphorylase from Listeria innocua [beta-1,2-mannobiose phosphorylase] (Mus musculus) PubMed

 16509.

mutation of FdC2 gene caused yellow-green leaf phenotype in rice.[FdC2] (Mus musculus) PubMed

 16510.

Thermal asymmetric interlaced PCR isolated one 1633-bp insertion in OsMADS3 in RI127S, which damaged its function due to failed transcription.[OsMADS3] (Mus musculus) PubMed

 16511.

A new fertility locus, Rf6, was able to restore male fertility on both A1 and A2 cytoplasms.[Rf6] (Mus musculus) PubMed

 16512.

FaNIP1;1 seems to play an important role increasing the plasma membrane permeability, that allows the water accumulation in the strawberry fruit receptacle throughout the ripening process.[FaNIP1;1] (Mus musculus) PubMed

 16513.

Mice infected with chuS-overexpressing Escherichia coli have more hepatic carbon monoxide and less serum IL-12 p40 than mice infected with chuS-deficient Escherichia coli.[chuS] (Mus musculus) PubMed

 16514.

Data suggest that Bdf2 and Bdf3 play roles in maintaining bloodstream stage of T. brucei and in immune evasion in a mouse model; studies include crystal structures of Bdf2/Bdf3. [Bdf2 and Bdf3] (Mus musculus) PubMed

 16515.

The study investigated the geometric structure of bound nitrite and the mechanism of nitrite reduction on copper-containing nitrite reductase using density functional theory calculations. [copper-containing nitrite reductase] (Mus musculus) PubMed

 16516.

These findings suggest that transcription of vap genes is regulated by VirS and that VirR is involved in the mechanism of transcriptional responses to temperature and pH.[VirS, VirR] (Mus musculus) PubMed

 16517.

Tyrosine Aminomutase catalyzes a mixture of (R)- and (S)-beta-tyrosine, but with very high enantioselectivity ( approximately 97%) for the R isomer. [Tyrosine Aminomutase] (Mus musculus) PubMed

 16518.

the novel transcription factor VvWRKY13 is likely involved in ethylene biosynthesis by the regulation of ACS2 and ACS8 expression.[WRKY13] (Mus musculus) PubMed

 16519.

The inactive diol dehydratase enzyme.cyanocobalamin complex were (re)activated by incubation with NADH, ATP, and Mg(2+) in crude extracts of Klebsiella oxytoca, suggesting the presence of a reactivating system in the extract. [diol dehydratase] (Mus musculus) PubMed

 16520.

crystal structures of the separase protease domain from the thermophilic fungus Chaetomium thermophilum, alone or covalently bound to unphosphorylated and phosphorylated inhibitory peptides derived from a cohesin cleavage site [separase] (Mus musculus) PubMed

 16521.

The data demonstrate that the fimbrial binding of F4(+) E. coli is directly mediated by the major FaeG subunit.[FaeG] (Mus musculus) PubMed

 16522.

Data suggest that substrate specificity of secreted zinc metalloendopeptidase CD2830 includes CD2831; cleavage of CD2831 by CD2830 appears to be involved in adhesion of Clostridium difficile to collagen I. [collagen-binding protein CD2831] (Mus musculus) PubMed

 16523.

Arginine 100 and aspartic acid 109 of the NAR2.1 protein are key amino acids in the interaction with NRT2.3a, and their interaction occurs in the plasma membrane but not cytoplasm. [NAR2.1] [NRT2.3a] (Mus musculus) PubMed

 16524.

Structural analysis of a fusion protein of CrRbcX-IIa and the C-terminal peptide of RbcL suggests that the peptide binding mode of RbcX-II may differ from that of cyanobacterial RbcX (Mus musculus) PubMed

 16525.

NBS1 is involved in DNA repair and normal development in P. oryzae. [NBS1] (Mus musculus) PubMed

 16526.

Aspartate decarboxylase (ADC) is required for a normal pupa pigmentation pattern in the silkworm. [ADC] (Mus musculus) PubMed

 16527.

MBI1 and MCG1 proteins stabilize chloroplast mRNA of psbI and petG proteins. [MBI1] [MCG1] (Mus musculus) PubMed

 16528.

the genetic diversity and antigenic heterogeneity of Ply and PhtD for 173 pneumococci isolated from invasive diseases in Korean children, were analyzed.[Ply, PhtD] (Mus musculus) PubMed

 16529.

Based on the results of the docking analysis of the effective mutants, we propose a linkage mechanism for the remote allosteric regulation of N-acetyl glutamate kinase activity, in which residue R209 may play an essential role.[N-acetyl glutamate kinase] (Mus musculus) PubMed

 16530.

Definitive evidence has been provided that C. trachomatis CT695 is secreted during infection. [CT695] (Mus musculus) PubMed

 16531.

The reaction pathway for ATP hydrolysis in the maltose ABC transportor ATPase is evaluated using a QM/MM implementation of the nudged elastic band method without presuming reaction coordinates. [maltose ABC transportor ATPase] (Mus musculus) PubMed

 16532.

Data suggest that failure to phosphorylate Zip1 4S (a conserved sequence region on C terminus of Zip1) results in meiotic prophase arrest. [Zip1] (Mus musculus) PubMed

 16533.

The N terminal loop (loop I) is closed within less than 60 mus after the initiation of refolding. [Adenylate Kinase] (Mus musculus) PubMed

 16534.

The results indicated that vitellogenin receptor was critical for vitellogenin uptake and ovary maturation in B. dorsalis, playing a vital role in female reproduction. [vitellogenin receptor, vitellogenin] (Mus musculus) PubMed

 16535.

By adhesion assays, showed that the mutant strain LM3-CC1, carrying a null mutation in the enoA1 gene, binds to immobilized collagen less efficiently than wild type strain.[EnoA1]. (Mus musculus) PubMed

 16536.

our findings suggest that MUS-30, an LSH/DDM1 homolog, is required to prevent DNA damage arising from toxic base excision repair intermediates (Mus musculus) PubMed

 16537.

Ref is especially toxic during the bacterial SOS response and the limited growth of stationary phase cultures, targeting aspects of bacterial physiology that are closely associated with the development of bacterial pathogen persistence. (Mus musculus) PubMed

 16538.

IcaA is a novel C. burnetii effector protein which interferes with the caspase-11-induced, non-canonical activation of the inflammasome. [IcaA] (Mus musculus) PubMed

 16539.

Results demonstrate that UIS2 is the eIF2alpha phosphatase in Plasmodium[UIS2] (Mus musculus) PubMed

 16540.

MpkA and MpkB are involved in cell wall biosynthesis and independently affect micafungin sensitivity in Aspergillus nidulans.[mpkA] [mpkB] (Mus musculus) PubMed

 16541.

Knocking out of amn gene enhanced intracellular ATP level and biomass formation.[amn] (Mus musculus) PubMed

 16542.

Hydrolase activities of N192P and D165P DamH were only 55.5% and 49.7% of the wild-type enzyme.[DamH] (Mus musculus) PubMed

 16543.

The distal pocket of CYP105D7 contains four arginine residues, forming a wall of the substrate-binding pocket. [CYP105D7] (Mus musculus) PubMed

 16544.

TaNAC29 plays important roles in the senescence process and response to salt and drought stresses. Abscisic acid signal pathway and antioxidant enzyme systems are involved in TaNAC29-mediated stress tolerance mechanisms.[NAC29] (Mus musculus) PubMed

 16545.

These results suggest that the serine-rich tract of the immediate early 62 protein plays an important role in varicella-zoster virus viral gene expression and replication.[immediate early 62 protein] (Mus musculus) PubMed

 16546.

PpMYB10.1 is a major regulator of anthocyanin accumulation in red-skinned peach and that it activates PpUFGT transcription. PpMYB10.2/3 may be involved in functions other than anthocyanin accumulation in peach. [MYB10.1,MYB10.2,MYB10.3] (Mus musculus) PubMed

 16547.

BdCarE4 and BdCarE6 function in conferring malathion resistance in Bactrocera dorsalis. [BdCarE4; BdCarE6] (Mus musculus) PubMed

 16548.

The differential expression of prx1 and ahpF is accomplished by the cis-acting transcriptional attenuator located between the two genes and thereby leads to the production of a high level of Prx1 and a low level of AhpF. (Mus musculus) PubMed

 16549.

Thermal stability of cytochrome c' from mesophilic Shewanella amazonensis [cytochrome c'] (Mus musculus) PubMed

 16550.

we show that the causative agent of Lyme disease, Borrelia burgdorferi, expresses a surface-protein termed BBK32 that targets and inhibits the first component of complement, designated C1 (Mus musculus) PubMed

 16551.

These results indicate that SucR and GntR3 are acting as activators of GlxR, while RamB plays a repressor.[GlxR] (Mus musculus) PubMed

 16552.

root meristem size in rice is modulated by SHB-mediated gibberellin biosynthesis. [SHOEBOX] (Mus musculus) PubMed

 16553.

Crystal structures of apo- and haemoglobin-bound HpuA are reported. The interface involves long loops on the bacterial receptor that present hydrophobic side chains for packing against the surface of haemoglobin. (Mus musculus) PubMed

 16554.

The GT-1 element directly controls the salt response of OsRAV2. [OsRAV2] (Mus musculus) PubMed

 16555.

The identified the Zds1/Zds2-protein phosphatase 2A(Cdc55) (PP2A(Cdc55)) complex as a novel Rho1 effector that regulates Rho1 signaling specificity.(ZDS1 protein, S cerevisiae) (Mus musculus) PubMed

 16556.

S10-ORF2 encodes a putative protein 50-59 residues in length and appears to be under strong positive selection. [S10-ORF2] (Mus musculus) PubMed

 16557.

LbHep1 protected, in sub-stoichiometric fashion, LbmtHsp70 from thermally induced aggregation but did not present intrinsic chaperone activity on model client proteins. Therefore, LbHep1 is a specific chaperone for LbmtHsp70. (Mus musculus) PubMed

 16558.

This study identified PA4184, or SouR (sarcosine oxidation and utilization regulator), as the sarcosine-responsive regulator of the sox operon, with tight induction specificity for sarcosine.[SouR] (Mus musculus) PubMed

 16559.

During arbuscule branching, EXO70I is located in spatially restricted zones adjacent to the PAM around the arbuscule hyphal tips where it interacts with Vapyrin, a plant-specific protein required for arbuscule development.[EXO70I] (Mus musculus) PubMed

 16560.

(Gene CBF2) J. curcas CBF2 transcripts express in leaves of Jatropha at cold temp. J. curcas CBF2 could also regulate transcripts of some cold-responsive (COR) genes in Arabidopsis thaliana such as RD29A, COR105A and COR6.6. (Mus musculus) PubMed

 16561.

Molecular dynamics simulations of the NS2B/NS3 protease complexes with 6 peptide substrates suggested that among the ten substrate residues (P(5)-P(5)') the P(1) and P(2) subsites play a major role in the binding with the focused protease. NS2B/NS3 (Mus musculus) PubMed

 16562.

YhdE dimerization and binding of dTTP induce the cooperative effect through a direct allosteric communication network in YhdE from the dTTP binding sites in the catalytic center to the intermolecular beta-strand in YhdE dimer.[YhdE] (Mus musculus) PubMed

 16563.

Heterologous inhibition of the F1-ATPase of P. denitrificans by the mitochondrial IF1 supported both the modeled zeta binding site at the alphaDP/betaDP/gamma interface and the endosymbiotic alpha-proteobacterial origin of mitochondria.[F1Fo ATPase] (Mus musculus) PubMed

 16564.

Data show that thiosugars bind to sodium-glucose co-transporters vSGLT and hSGLT2 stronger and dissociate more slowly than sugars: [vSGLT; SGLT] (Mus musculus) PubMed

 16565.

A comparison with the previously well characterized type I TA system from the B. subtilis chromosome, bsrG/SR4, reveals similarities but also significant differences.[bsrE, SR5] (Mus musculus) PubMed

 16566.

The N terminus of LubX is able to activate an extended number of ubiquitin-conjugating enzymes. [LubX] (Mus musculus) PubMed

 16567.

These results demonstrate that extracellular fatty acids are activated by an acyl-acyl carrier protein synthetase (AasN) and validate type II fatty acid synthesis (FabI) as a therapeutic target against Neisseria.[ACP, FabI] (Mus musculus) PubMed

 16568.

cloning of BnRfb , which encodes a nucleus-localized chimeric protein BnaA7.mtHSP70-1-like male sterility gene [BnRfb] (Mus musculus) PubMed

 16569.

The results suggested that deletion of SrtA reduced the bacterial burden on the heart, liver and kidneys by blunting the host proinflammatory cytokine response at an early point in infection.[SrtA] (Mus musculus) PubMed

 16570.

these null mutants are completely avirulent following injection into BALB/c mice, underscoring the critical role of the KHARON1 protein for viability of intracellular amastigotes and disease in the animal model of leishmaniasis. (Mus musculus) PubMed

 16571.

Multidomain staphylococcal protein A (SpA) is flexible and binds to many proteins.Backbone and side chain conformations are coupled to a pivot of helix 1 around Ile16.[SpA] (Mus musculus) PubMed

 16572.

These results delineate the functional relevance of atomic interactions inferred from structure, and suggest that the ribozyme transition state resembles the cleavage product in the degree of proton transfer to the leaving group. [Ribozyme] (Mus musculus) PubMed

 16573.

Chu_1719 gene inactivation resulted in a compromised growth and cellulose utilization. [chu_1719] (Mus musculus) PubMed

 16574.

Sigma 54 in B. cereus plays a role in degradation of branched chain amino acids, carbohydrate transport and metabolism, flagella synthesis and virulence factors. RpoN. (Mus musculus) PubMed

 16575.

TaATG6a, 6b and 6c were localized on homeologous chromosomes 3DL, 3BL and 3AL, respectively, of the allo-hexaploid wheat genome, and evidence was provided for their essential role in autophagy.[ATG6a,ATG6b,ATG6c] (Mus musculus) PubMed

 16576.

CDKA2 was found to interact with the G2/M-specific CDK scaffolding factor CKS1. Localization of CDKA2 was found to be nuclear in interphase cells, while in cells undergoing cytokinesis, the signal extended to the cell division plane.[CKS1] (Mus musculus) PubMed

 16577.

Ca(2+) binding to Cut190 enhances thermostability and activity of polyethylene terephthalate degradation activity. [Cut190] (Mus musculus) PubMed

 16578.

The phosphatidylinositol-phosphate synthase with bound CDP-diacylglycerol at 3.6 A resolution.[phosphatidylinositol-phosphate synthase ] (Mus musculus) PubMed

 16579.

Mutations of the mdr1 gene that covered codons 86, 184, 1034, and 1246 were found in Plasmodium falciparum isolates in returned from Ghana migrant workers in China. [MDR1] (Mus musculus) PubMed

 16580.

Results suggest a specific involvement of Heat shock protein 70 (Hsp70) Ssa5 in pronuclear fusion and fertilization [HSP70 Ssa5] (Mus musculus) PubMed

 16581.

role of Cdh1 in internalization of a virus (Mus musculus) PubMed

 16582.

Crystal structure of the NikA reveal nickel binding motifs.[NikA] (Mus musculus) PubMed

 16583.

Phe187 Is essential for integrase dimerization.[integrase] (Mus musculus) PubMed

 16584.

Results show the expression of sncRNA715 in Schwann cells and its inverse correlation with Mbp mRNA in cultured cells and the sciatic nerve. Its inhibitory effect on MBP was confirmed in differentiating primary Schwann cells. [SncRNA715] (Mus musculus) PubMed

 16585.

These results suggest that the orientation of the protein during DNA-binding is significantly different when comparing D radiodurans RecQ and E coli RecQ.[RecQ] (Mus musculus) PubMed

 16586.

MJ0927 adopts a novel quartenary architecture that could play various DNA-binding roles in Methanocaldococcus jannaschii.[MJ0927] (Mus musculus) PubMed

 16587.

ZmpTAC12 interacts with single-stranded nucleic acids and is required for the proper build-up of the PEP-complex. (Mus musculus) PubMed

 16588.

The present study was undertaken for identification of metalloprotease produced by Bacillus cereus B80.[Metalloprotease] (Mus musculus) PubMed

 16589.

Here, it was shown that MucR impairs alginate production in response to nitrate in Pseudomonas aeruginosa.[MucR] (Mus musculus) PubMed

 16590.

PXG-deficient Aspergillus flavus strains were severely compromised in their capacity to infect maize seeds and to produce aflatoxin.[PXG] (Mus musculus) PubMed

 16591.

AguR is a transmembrane protein which might function as a one-component signal transduction system that senses the agmatine concentration of the medium and, accordingly, regulates the transcription of the aguBDAC operon.[AguR] (Mus musculus) PubMed

 16592.

The study experimentally detects the reversible switching between two alternative electronic states that confer different directionalities to the redox reaction in Cu(A) sites of cytochrome ba3. [cytochrome ba3] (Mus musculus) PubMed

 16593.

the requirements for Mec1 activation, were determined.[Mec1] (Mus musculus) PubMed

 16594.

These results show that MoFIS1 encodes a mitochondrial protein that regulates fungal growth, conidiation, and virulence in Magnaporthe oryzae.[MoFIS1] (Mus musculus) PubMed

 16595.

Data indicate that mitochondrial tryparedoxin peroxidase (TcMPx) gene (AJ006226) is distributed throughout the cell and TcMPx interaction partners change following oxidative stress exposure: [TcMPx; MPx) (Mus musculus) PubMed

 16596.

p17 functions as a nucleoporin Tpr suppressor that leads to p53 nuclear accumulation and consequently activates p53, p21, and PTEN. [p17] (Mus musculus) PubMed

 16597.

Results show that FgSge1 is localized in the nucleus and protein kinase A phosphorylation site is required for its function. [Sge1] (Mus musculus) PubMed

 16598.

This study showed that the AcrB-AcrA 1:1 fusion protein is active for drug export under mutated conditions indicating that the 1:1 stoichiometry is enough for drug export function.[AcrA; AcrB] (Mus musculus) PubMed

 16599.

An apparent meso-hydroxyheme (forming with k = 0.6 min(-1), pH 7.4, 10 mm ascorbate, 10 mum IsdG-heme, 22 degrees C) was identified as a likely common intermediate with the canonical heme oxygenases.[IsdG] (Mus musculus) PubMed

 16600.

A conserved loop of the Piezo channel is identified that forms a stable domain.The structure of this domain reveals a topologically distinct beta sandwich fold.[Piezo] (Mus musculus) PubMed

 16601.

discovery of a gene regulatory network related to the porcine umami taste receptor TAS1R1/TAS1R3 [TAS1R1] (Mus musculus) PubMed

 16602.

MRTF down-regulation/inhibition suppresses TGFbeta/contact disruption-provoked Nox4 protein and mRNA expression, Nox4 promoter activation, and reactive oxygen species production.[MRTF] (Mus musculus) PubMed

 16603.

Overall, these results provide the first evidence that EfeB plays a role in protecting cells of Streptococcus thermophilus from oxidative stress, with the assistance of the twin-arginine translocation system.[EfeB] (Mus musculus) PubMed

 16604.

The study concludes that cooperative electrostatic interactions drive functional evolution in the alkaline phosphatase superfamily [Alkaline Phosphatase] (Mus musculus) PubMed

 16605.

A novel galactofuranose-specific beta-D-galactofuranosidase from Streptomyces species has been identified and characterized. [beta-D-galactofuranosidase] (Mus musculus) PubMed

 16606.

the crystal structure of the UBL domain of the WDR12 homologue from S. cerevisiae at 1.7 A resolution is reported and demonstrated that human midasin binds to WDR12 as well as Nle1 through their respective UBL domains.[Ytm1] (Mus musculus) PubMed

 16607.

membrane-lytic activity of PB1-F2 is closely linked to supramolecular organization of the protein.[PB1-F2] (Mus musculus) PubMed

 16608.

KdpD senses at least two distinct signals inside the cell, those of Na(+) and NH4 (+), and it probably senses other monovalent cations in the cell.[KdpD] (Mus musculus) PubMed

 16609.

Results identified a duplicated V3 domain in the HCV-1b NS5A protein for the first time. The duplication may be associated with unfavorable evolution of liver disease including a possible involvement in liver carcinogenesis. (Mus musculus) PubMed

 16610.

Study identified two new PKDCC genes, Pkdcc1 and Pkdcc2 from Xenopus laevis. They seem involved on blastopore and neural tube closure during gastrula and neurula stages, respectively. Also, they seem to regulate JNK dependent Wnt/PCP signaling. [Pkdcc2] (Mus musculus) PubMed

 16611.

The interaction between PCV2 ORF2 and C1QBP inhibited ubiquitin-mediated proteasomal degradation of C1QBP in macrophages. [C1QBP] (Mus musculus) PubMed

 16612.

24% sequence identity and 40% similarity with human ferroportin [FPN] (Mus musculus) PubMed

 16613.

Pro88 and Leu315 are close to each other by dimerization. Binding of the inhibitor with S. gordonii FabH enhanced the structure and stabilized the dimeric FabH protein. (Mus musculus) PubMed

 16614.

A novel S-enantioselective amidase acting on 3,3,3-trifluoro-2-hydroxy-2-methylpropanamide was purified from Arthrobacter sp. S-2. [Amidase] (Mus musculus) PubMed

 16615.

the novel lncRNA gene, which we designated pouBW1, might play an important role in regulating chicken growth [pouBW1] (Mus musculus) PubMed

 16616.

Genomic organization, polymorphism, chromosomal assignment and spatial and temporal expressions of EEF1A2 gene was presented (EEF1A2). (Mus musculus) PubMed

 16617.

Pseudomonas syringae type III effector protein AvrB induces stomatal opening and enhances bacterial virulence in a manner dependent on RIN4, which promotes stomatal opening by positively regulating the Arabidopsis plasma membrane H(+)-ATPase.[AvrB] (Mus musculus) PubMed

 16618.

Data suggest decarboxylation of para- coumaric acid by PAD involves mechanism (involving Glu64) in which quinone methide intermediate is formed by protonation of substrate double bond, followed by C-C bond cleavage. [PAD, phenolic acid decarboxylase] (Mus musculus) PubMed

 16619.

the periplasmic expression of BSH by signal peptides from the Tat pathway, is reported.[Bile salt hydrolase] (Mus musculus) PubMed

 16620.

In contrast, inhibition of the protease activity of Kgp, RgpA or RgpB increased the human caspase-1-activating potential of wild-type Porphyromonas gingivalis, indicating an inhibitory effect of the collaborative action of gingipains.[Kgp, RgpA, RgpB] (Mus musculus) PubMed

 16621.

interactions between miR-26 and the Smad1 3'UTR modulate Smad1 function in the establishment of axial patterning.[miR-26] (Mus musculus) PubMed

 16622.

type V-A Cpf1 from Francisella novicida is a dual-nuclease that is specific to crRNA biogenesis and target DNA interference; type V-A constitutes the most minimalistic of the CRISPR-Cas systems so far described [Cpf1] (Mus musculus) PubMed

 16623.

Free Energy Landscapes for the Opening-Closing Dynamics of the Maltose Transporter ATPase MalK2 [Malk2] (Mus musculus) PubMed

 16624.

These results uncovered the mysteries about rabbit amelogenin and revealed its sequence peculiarities.[Amelogenin] (Mus musculus) PubMed

 16625.

GRA7-induced MyD88 signaling through the activation of TRAF6 and production of reactive oxygen species is required for the induction of NF-kappaB-mediated proinflammatory responses by macrophages. (Mus musculus) PubMed

 16626.

A structural study of inhibition of Klebsiella beta-Lactamases (SHV-1 and KPC-2) by avibactam demonstrates the importance of critical amino acid residues to counter the drug resistance. [SHV-1] (Mus musculus) PubMed

 16627.

Dielectric Constant in the Trichoderma reesei Cel7B Active Site [Cel7B] (Mus musculus) PubMed

 16628.

These studies indicate that sphingosine kinase is involved in G1-to-S cell cycle progression, organelle positioning, and maintenance of cell morphology.[sphingosine kinase] (Mus musculus) PubMed

 16629.

conformational changes play a major role in the thiol- and flavin-based electron-transfer mechanism [quiescin sulfhydryl oxidase] (Mus musculus) PubMed

 16630.

Disruption of grr1 resulted in defects in vegetative growth, melanin pigmentation, conidial production, and resistance to oxidative stress. [Grr1] (Mus musculus) PubMed

 16631.

SlyA protein directly binds to the promoter region of PhoP; SlyA regulates virulence by controlling multiple pathogenicity-related genes directly and/or at least by controlling PhoP in D. dadantii 3937 when magnesium is low [SlyA] (Mus musculus) PubMed

 16632.

study identified a novel bacteriocin operon for leucocin B expression in L. carnosum 4010 and further studied bacteriocin production in native and heterologous hosts [leucocin B] (Mus musculus) PubMed

 16633.

The BT1927 surface layer protein-expressing subpopulation is profoundly resistant to complement-mediated killing, due in part to the BT1927-mediated blockade of C3b deposition.[BT1927] (Mus musculus) PubMed

 16634.

Data suggest that affinity of uridylylated forms of the PII nitrogen regulatory proteins GlnB and GlnK for nucleotides (ATP, ADP) is significantly lower than that of the non-uridylylated proteins. [GlnB and GlnK] (Mus musculus) PubMed

 16635.

Nrp1 in endothelial cells suppresses TGFbeta activation and signaling by forming intercellular protein complexes with beta8 integrin.[Tgfb] (Mus musculus) PubMed

 16636.

These results indicate that conserved IL-2Rgammac signaling via JAK3 plays a key role during early zebrafish lymphopoiesis, which can be potentially targeted to generate a zebrafish model of human Severe Combined Immunodeficiency. [IL-2Rgammac] (Mus musculus) PubMed

 16637.

the prevalence of H. pylori infection and diversity of CagA phenotype contributes to the variety of gastric cancer risk in various regions of Thailand.[CagA] (Mus musculus) PubMed

 16638.

These data suggest that miR-BART20-5p plays an important role in latency maintenance and tumor persistence of Epstein-Barr virus-associated gastric carcinoma by inhibiting BAD-mediated caspase-3-dependent apoptosis.[miR-BART20-5p] (Mus musculus) PubMed

 16639.

EscE is secreted and translocated in a type III secretion system-dependent manner and amino acids 2 to 15 in the N terminus were required for a completely functional type III secretion system in E. tarda. (Mus musculus) PubMed

 16640.

A novel beta-glucosidase of glycoside hydrolase (GH) family 3 from Myceliophthora thermophila (mtbgl3b) was successfully expressed in Pichia pastoris.[Mtbgl3b] (Mus musculus) PubMed

 16641.

Inherent flexibility of the PB2 polymerase from H5N1 (Vietnam/1203/2004) allows it to adopt alternative conformations that are likely important during polymerase maturation into active progeny RNPs. (Mus musculus) PubMed

 16642.

In the presence Streptococcus pyogenes NAD(+) glycohydrolase (SPN), host cell ATP is depleted and the pro-inflammatory mediator high-mobility group box-1 (HMGB1) protein is released from the nucleus by a PARP-1-dependent mechanism.[SPN] (Mus musculus) PubMed

 16643.

Naked kernels during Maize domestication was caused by a single amino acid substitution in tga1. (Mus musculus) PubMed

 16644.

MdtJI expression is increased by the high levels of spermidine typically found in this microorganism and by VirF, the plasmid-encoded regulator of the Shigella virulence regulatory cascade.[Mdtji] (Mus musculus) PubMed

 16645.

the entire onecut locus and its flanking region for transcriptionally active cis-regulatory elements, was screened.[onecut] (Mus musculus) PubMed

 16646.

Escherichia coli PspA has an enhanced sensitivity for curvature elastic (SCE) stress and a higher affinity for the membrane than Synechocystis Vipp1.[Vipp1] (Mus musculus) PubMed

 16647.

The presence of ACAM in ascidians highlights the diversity of this gene family in morphogenesis and neurodevelopment.[ACAM] (Mus musculus) PubMed

 16648.

Data suggest Toxoplasma gondii ME49 expresses pts in its endoplasmic reticulum; non-functioning mutant pts alters virulence/lytic cycle/encystment and prevents acute/chronic toxoplasmosis in mouse model. [pts, phosphatidylethanolamine synthase] (Mus musculus) PubMed

 16649.

PsXEG1 contributes to P. sojae virulence, but soybean recognizes PsXEG1 to induce immune responses.[PsXEG1] (Mus musculus) PubMed

 16650.

Residue E419 of the HC-Pro protein is linked to the ability of PVY to induce tuber necrosis. [HC-Pro] (Mus musculus) PubMed

 16651.

The genomic scale of GrvA-dependent regulation via GadW and GadE and its role in the pathogencity of enterohemorrhagic Escherichia coli are reported. [GrvA] (Mus musculus) PubMed

 16652.

The present study explains the concomitant conformational changes observed with GroEL hinge variants and is best supported by the normal mode analysis.[GroEL2] (Mus musculus) PubMed

 16653.

in silico analysis revealed several candidate cis-regulatory elements that PMtSEO-F1 shares with other sieve element occlusion promoters.[SEO-F1] (Mus musculus) PubMed

 16654.

BnMAM1, BnCYP83A1 and BnUGT74B1 are all highly responsive to S. sclerotiorum and B. cinerea infection, and overexpression of these three genes led to marked increase in either or both of aliphatic and indolic GSLs levels in leaves (Mus musculus) PubMed

 16655.

SBP2 mediates uptake of arginine, a strict growth requirement of M. catarrhalis.The critical role of SBP2 in arginine uptake may contribute to its potential as a vaccine antigen.[SBP2]. (Mus musculus) PubMed

 16656.

A mutant NspA vaccine engineered to have decreased binding to human complement factor H may increase protective antibody responses in humans.[NspA]. (Mus musculus) PubMed

 16657.

GraS mediates specific resistance countermeasures to Host Defense Peptides in immune contexts that are highly relevant to S. aureus pathogenesis in humans.[GraS] (Mus musculus) PubMed

 16658.

Present data on ALL2's unique function in maintaining intracellular pH in low-pH conditions.Data highlight that C. neoformans, a human-pathogenic basidiomycete, has evolved a unique set of virulence-associated genes.[ALL2]. (Mus musculus) PubMed

 16659.

the glpX encoded FBPase II in Mycobacterium tuberculosis can be a potential target for drug discovery.[glpX] (Mus musculus) PubMed

 16660.

This study identified and characterized a novel lipase denoted LipL from M. tuberculosis.[LipL] (Mus musculus) PubMed

 16661.

Energy Landscape of the Protein IscU [IscU] (Mus musculus) PubMed

 16662.

Data suggest that araR (and DNA-binding domain polypeptide fragment of araR) exhibits plasticity/anisotropy in interactions with various operator regions of DNA (AT-rich sequences/polydeoxyribonucleotides). [araR, transcriptional repressor] (Mus musculus) PubMed

 16663.

the Glu45 residue at the active site of PhzF acts as a general base/acid catalyst during proton transfer.[PhzF] (Mus musculus) PubMed

 16664.

these data establish the architectural organization of Pf41 and define an essential role for the Pf41 Intra-Domain in promoting assembly of the Pf12-Pf41 heterodimeric complex.[Pf41] (Mus musculus) PubMed

 16665.

cardinal plays a major role in ommochrome synthesis of holometabolous insects [cardinal] (Mus musculus) PubMed

 16666.

These results suggested that BdFoxO plays an important role in body size and development in B. dorsalis. (Mus musculus) PubMed

 16667.

structure of the pore domain of mitochondrial calcium uniporter (MCU) from Caenorhabditis elegans, determined using nuclear magnetic resonance and electron microscopy [MCU] (Mus musculus) PubMed

 16668.

Data suggest that PME exhibits distinctive pH optimum (mildly acidic), salt requirements (moderate ionic strength), substrate specificity, amino acid sequence, and protein conformation. [PME, pectin methylesterase] (Mus musculus) PubMed

 16669.

The enzyme exhibits dimer geometry. A patch of four aromatic amino acids, embedded into a ring of hydrophobic residues, further stabilized by a network of H-bonds, is essential for the stability of the dimer's contact. [tRNA-guanine transglycosylase] (Mus musculus) PubMed

 16670.

this analysis provided structural and mechanistic insights to the degree of dapsone resistance contributed by each of these DHPS mutants in leprosy. (Mus musculus) PubMed

 16671.

This study demonstrates that smooth and rough isolates of Arcanobacterium haemolyticum can be genetically distinguished at the arcanolysin locus. [arcanolysin] (Mus musculus) PubMed

 16672.

The study reports the discovery of a Brassica napus gene encoding a novel proline-rich antimicrobial peptide. This gene encodes a 35-amino acid peptide with 13 proline residues, designated BnPRP1. [BnPRP1] (Mus musculus) PubMed

 16673.

New sigma factor E regulated genes (greA, luxS, ompA and ompX) are shown to be involved in heat shock and oxidative stress responses. [sigma factor E] (Mus musculus) PubMed

 16674.

This study provides new insight into the cellulose binding properties of the carbohydrate binding modules (CBMs) from the oomycetal protein CBEL and reveals that CBM1-1 is probably the major determinant of CBEL's interaction with cellulose. [CBEL] (Mus musculus) PubMed

 16675.

These findings suggest that loss of Fmrp results in increased Adar-mediated RNA editing activity on target-specific RNAs, which, in turn, might alter neuronal circuit formation and behavior in FXS. (Mus musculus) PubMed

 16676.

Data suggest DndEi plays essential role in phosphorothioate (PT) modification of DNA; DndEi exhibits helicase and APTase activities (strongly stimulated by substrate containing GAAC/GTTC motif, same as for PT modifications). [DndEi, DNA helicase] (Mus musculus) PubMed

 16677.

Our findings establish a framework for plant drought and salt stress tolerance through the DCA1-DST-Prx24 pathway (Mus musculus) PubMed

 16678.

Telomere abnormalities are telomerase-independent, but dramatically suppressed by deletion of mre11 or blm, suggesting major roles for these factors in the induction of the ALT pathway (Mus musculus) PubMed

 16679.

we demonstrate that the amount of FLAM3 and its localisation is dependent on ClpGM6 expression and vice versa. This evidence demonstrates that FAZ is a key regulator of trypanosome shape, with experimental perturbations being life cycle form dependent. (Mus musculus) PubMed

 16680.

This study revealed a significant association between the polymorphism SNP183 on chromosome 6 and bolting tendency in sugar beet. SNP183 was mapped to the intron sequence of the sugar beet gene Bv_22330_orky, that codes for a matrix metalloproteinase. [Bv_22330_orky, a matrix metalloproteinase] (Mus musculus) PubMed

 16681.

After analyzing the patterns of conservation for the S15 protein coding sequences, we also identified amino acid changes that alter the binding specificity of an S15 homolog. (Mus musculus) PubMed

 16682.

The authors found that Junonia coenia densovirus non-structural (NS) protein expression correlates with the inhibition of Lymantria dispar TOR and the shutdown of cellular synthesis.[TOR] (Mus musculus) PubMed

 16683.

B. abortus inhibits matrix metalloproteinase 9 (MMP-9) secretion through the activity of the BPE005-secreted protein and induces concomitant collagen deposition by LX-2 cells.[BPE005]. (Mus musculus) PubMed

 16684.

OsPP108 protein phosphatase confers abscisic acid insensitivity and abiotic stress tolerance. [OsPP108] (Mus musculus) PubMed

 16685.

Silencing of polygalacturonase or pectate lyase genes reduces strawberry softening. [polygalacturonase, pectate lyase] (Mus musculus) PubMed

 16686.

Trypanosome EVs contain several flagellar proteins that contribute to virulence, and Trypanosoma brucei rhodesiense EVs contain the serum resistance-associated protein (SRA) necessary for human infectivity. T. b. rhodesiense EVs transfer SRA to non-human infectious trypanosomes, allowing evasion of human innate immunity. [SRA from Trypanosoma brucei rhodesiense] (Mus musculus) PubMed

 16687.

Amino acid 512 in beta-glucosidase determines the regioselectivity for hydrolyzing gypenoside.[beta-glucosidase] (Mus musculus) PubMed

 16688.

The crucial role of the first His triad site of PhtD in zinc acquisition is highlighted. Study also suggested that the Pht proteins likely play a role beyond zinc acquisition in pneumococcal virulence.[PhtD]. (Mus musculus) PubMed

 16689.

results demonstrate that B. ovis is able to persist and multiply in ovine macrophages, while DeltaabcBA and DeltavirB2 mutations prevent intracellular multiplication, favor phagolysosome fusion, and impair maturation of the B. ovis vacuole (Mus musculus) PubMed

 16690.

Kinetic studies show that beta-lactamase OXA-51 has low catalytic efficiency for carbapenems, primarily due to the low affinity of the enzyme for these substrates. [beta-lactamase OXA-51] (Mus musculus) PubMed

 16691.

MarA and RamA not only regulate drug resistance but also play a role in the virulence of Salmonella Choleraesuis. [marA; ramA] (Mus musculus) PubMed

 16692.

The authors found that Junonia coenia densovirus non-structural (NS) protein expression correlates with the inhibition of Lymantria dispar TOR and the shutdown of cellular synthesis.[NS] (Mus musculus) PubMed

 16693.

conclusion, TTD14 is a novel regulator of TRPL trafficking, involved in internalization and subsequent sorting of TRPL into the recycling pathway that enables this ion channel to return to the plasma membrane (Mus musculus) PubMed

 16694.

Data suggest Leishmania donovani Bob has genetic material capable of expression of selenocysteinyl-tRNA synthase; however, expression of selenoproteins are not required for growth/infectivity of L. donovani. [SepSecS, selenocysteinyl-tRNA synthase] (Mus musculus) PubMed

 16695.

The rice CHD3 protein CHR729 plays an important role in many aspects of seedling development. [CHR729] (Mus musculus) PubMed

 16696.

These data show that Mot1 reduces DNA:NC2 interactions and unbends DNA as compared to the TBP:DNA:NC2 state, suggesting that Mot1 primes TBP:NC2 displacement in an ATP-independent manner.[TBP, Mot1] (Mus musculus) PubMed

 16697.

These data demonstrate that lysine 12 is targeted for proteasomal degradation of AQP1 and plays an integral role in subcellular localization of AQP1 as well as its interaction with MPK2. (Mus musculus) PubMed

 16698.

Ime2 functions in regulation of the expression of cellulase gene in Trichoderma reesei.[Ime2] (Mus musculus) PubMed

 16699.

YrSM139-1B is a stripe rust resistance gene [YrSM139-1B] (Mus musculus) PubMed

 16700.

The authors propose an essential role for PPLP4 in infection of the mosquito midgut, presumably by mediating ookinete traversal through the midgut epithelium.[PPLP4] (Mus musculus) PubMed

 16701.

The engineering of LacI to respond to fucose, gentiobiose, lactitol or sucralose is reported [LacI] (Mus musculus) PubMed

 16702.

NblA is essential for degradation of the core complex of the phycobilisome (NblA). (Mus musculus) PubMed

 16703.

The mechanism of inhibition of its ATP hydrolytic activity involves a zeta inhibitor protein, which binds to the catalytic F-domain of the enzyme. (F-ATPase) (Mus musculus) PubMed

 16704.

MyoD1a and MyoD1b genes have an important influence on meat quality or were linked to the major genes in these strains. These genes can be used to control muscle fiber traits in rainbow trout. (Mus musculus) PubMed

 16705.

Tril is a homeodomain-leucine zipper gene involved in multicellular trichome initiation in Cucumis sativus [Tril] (Mus musculus) PubMed

 16706.

CGI-58 acts as a co-activator of ATGL-1, while it also functions cooperatively to maintain regular lipid droplet structure. (Mus musculus) PubMed

 16707.

results revealed, unexpectedly, that full-length FhaB plays a critical role in B. bronchiseptica persistence in the lower respiratory tract.[FhaB] (Mus musculus) PubMed

 16708.

osaA (Orchestrator of Sex and Asex)is an upstream orchestrator of morphological and chemical development that functions downstream of VeA. (Mus musculus) PubMed

 16709.

Data suggest expression of NFKB (nuclear factor kappa B) and TLR4 (toll-like receptor 4) are regulated by dietary factors; here, Lactobacillus acidophilus in feed down-regulates expression of NFKB/TLR4 in mononuclear cells after LPS challenge. [NFKB] (Mus musculus) PubMed

 16710.

Results suggest that alternative splicing of TRalpha2 evolved by stepwise exaptation of existing elements within and adjacent to the coding sequences for TRalpha1 and Reverbalpha suggesting a novel mechanism in which a G-rich structure regulates mRNA splicing. [TRA2] (Mus musculus) PubMed

 16711.

the opening of the OCP during photoactivation is caused by the movement of the C-terminal domain with respect to the N-terminal domain and the N-terminal arm.[OCP] (Mus musculus) PubMed

 16712.

In the absence of any amphiphilic peptide in PBP4a, the crown of positive charges on the surface of domain II is likely responsible for the cellular localization of this PBP and its attachment to the cytoplasmic membrane.[PBP4a] (Mus musculus) PubMed

 16713.

NADP(+) negatively regulates the acetyltransferase,Mxan_3215. [Kat] (Mus musculus) PubMed

 16714.

Characterize activity of triacylglycerol lipase Tgl1 in the diatom Phaeodactylum tricornutum. (Mus musculus) PubMed

 16715.

OsAUX1 plays an important role in root development and in responses to Cadmium stress (OsAUX1). (Mus musculus) PubMed

 16716.

These data support a model whereby suppressed expansion in green revolution gibberellic acid genes involves regulation of cellulose biosynthesis.[GA20 oxidase] (Mus musculus) PubMed

 16717.

Reduced expression of lipoxygenase in banana led to enhanced resistance towards Fusarium infection (lipoxygenase). (Mus musculus) PubMed

 16718.

These results demonstrated that htpsC was involved in the pathogenesis of the highly virulent Streptococcus suis 2 strain 05ZYH33.[htpsC] (Mus musculus) PubMed

 16719.

Cells lacking lptD had a growth defect comparable to that of an lpxC deletion mutant. [ lptD ] (Mus musculus) PubMed

 16720.

overexpression of maize ARGOS1 (ZmARGOS1), ZmARGOS8, Arabidopsis ARGOS homolog ORGAN SIZE RELATED1 (AtOSR1), and AtOSR2 reduced plant sensitivity to ethylene, leading to enhanced drought tolerance.[ARGOS] (Mus musculus) PubMed

 16721.

OsORAP1 enhanced cell death in ozone stress, and its expression levels could explain the effect of a previously reported quantitative trait locus.[OsORAP1] (Mus musculus) PubMed

 16722.

These studies used a green fluorescent protein based assay to correlate the the activities of Phosphatidylglycerol:prolipoprotein diacylglyceryl transferase (Lgt) with structural observations.[LGT] (Mus musculus) PubMed

 16723.

This is the first study to present the oligomerization of SrtA and its related biological function on the cell membrane.[SrtA] (Mus musculus) PubMed

 16724.

phylogenetic analyses indicated that the TgROP8 gene is not a suitable genetic marker for population studies of T. gondii.[TgROP8] (Mus musculus) PubMed

 16725.

study showed a significant association between the presence of the cagA gene and gastric cancer and peptic ulcer disease, and between anti-CagA IgG and the cagA gene in Saudi patients [cagA] (Mus musculus) PubMed

 16726.

fungal effector, AVR-Pii, interaction with OsExo70-F3 appears to play a crucial role in immunity triggered by Pii, suggesting a role for OsExo70 as a decoy or helper in Pii/AVR-Pii interactions (OsExo70-F3). (Mus musculus) PubMed

 16727.

These results suggest that nitrogen depletion decreases Tor2 activity through Tsc2, thereby promoting the surface expression of Agp3 from trans-Golgi/endosomes. [Agp3] (Mus musculus) PubMed

 16728.

Rice Exo70 interacts with a fungal effector, AVR-Pii, and is required for AVR-Pii-triggered immunity.[AVR-Pii] (Mus musculus) PubMed

 16729.

Study reports molecular cloning and characterization of a novel DNA polymerase, LF Gss pol, from Geobacillus sp. 777. LF Gss pol is more resistant to inhibitors than LF pol from Bacillus smithii or from Geobacillus stearothermophilus. [LF Gss pol] (Mus musculus) PubMed

 16730.

Pbo-1 regulates the membrane localization and activity of NHX-2/-7 in C.elegans. (Mus musculus) PubMed

 16731.

TaXA21-A1 confers unique resistance against multiple pests in wheat [TaXA21-A1] (Mus musculus) PubMed

 16732.

Here, the authors describe a second rhamnogalacturonan lyase, called PcRGLX, that demonstrated specific activity against rhamnogalacturonan but not against homogalacturonan.[PcRGLX] (Mus musculus) PubMed

 16733.

Mutational analysis shows that NHL13 is required for plant immunity.[AvrE] (Mus musculus) PubMed

 16734.

conclusive evidence at the protein level that CLJU_c23220 is the key gene responsible for the conversion of acetoin to 2,3-butanediol (acetoin reductase/2,3-butanediol dehydrogenase CLJU c23220) (Mus musculus) PubMed

 16735.

In V. cholerae, CytR is a global regulator of multiple behaviors affecting fitness and adaptability in the environment.[CytR] (Mus musculus) PubMed

 16736.

ChiB is negatively controlled by both CcpA and YvoA.[YvoA and CcpA, chiB] (Mus musculus) PubMed

 16737.

PIN5b modulates rice plant architecture and yield by changing auxin homeostasis, transport and distribution.[pin5b] (Mus musculus) PubMed

 16738.

These results show that the FIKK8 protein kinase targets serine, preferably with arginine in the +3 and -3 positions.[FIKK8] (Mus musculus) PubMed

 16739.

The results of this new study demonstrate that the very amino-terminal Venezuelan equine encephalitis virus capsid-specific subdomain SD1 is a critical player in the particle assembly process. (Mus musculus) PubMed

 16740.

Mutation of glycine (G) to aspartic acid (D) at position 622 in PB1 partially impaired the binding of PB1 to viral RNA, thereby dramatically decreasing the polymerase activity and attenuating H5N1 virus virulence in mice.[PB1] (Mus musculus) PubMed

 16741.

IscN was found to be important for diazotrophic growth when Fe-nitrogenase is used but dispensable for N2 reduction by Mo-nitrogenase. [IscN] (Mus musculus) PubMed

 16742.

This is the first report of the generation of a genetic AQP1 null mutant in Leishmania parasite, confirming its physiological function and role in resistance to antimonials, the therapeutic mainstay against Leishmania. (Mus musculus) PubMed

 16743.

These data establish a key role that miR528 plays in modulating plant growth and development.[miR528] (Mus musculus) PubMed

 16744.

JY-1 gene: Polymorphism in 3'UTR of the JY-1 gene is not associated with the reproductive traits of goats. (Mus musculus) PubMed

 16745.

the biochemical characteristics of PeAPY2 and its role in cold tolerance, was investigated.[APYRASE2] (Mus musculus) PubMed

 16746.

RecN is a first responder to DNA DSBs. RecN is present at early stages of heterocyst differentiation, but disappears in mature heterocysts. (Mus musculus) PubMed

 16747.

Though both G-domains possess "phosphate binding loop containing nucleoside triphosphate hydrolases fold", only the N-terminal domain binds to guanine nucleotide. (Mus musculus) PubMed

 16748.

We find that reduction of Htt levels affects cilia polarity and function and causes whole body paralysis. Moreover, Htt loss of function leads to abnormal development of trigeminal and motor neurons. (Htt, huntingtin) (Mus musculus) PubMed

 16749.

aa 89-96 of flagellin is not only the crucial site responsible for TLR5 recognition, but is also important for humoral immune adjuvanticity through a TLR5-independent pathway.[Flagellin] (Mus musculus) PubMed

 16750.

the roles of CTR1-related proteins appear to have functionally diversified during land-plant evolution.[CTR1L] (Mus musculus) PubMed

 16751.

The effects of genetic deletion of irp2 and fyuA on avian pathogenic E. Coli (APEC) were more severe than those produced by deletion of irp2 only, indicating that irp2 and fyuA co-regulate APEC pathogenicity.[irp2; fyuA] (Mus musculus) PubMed

 16752.

These results demonstrate that deletion of PhoP or PhoQ inhibits invasion and adhesion of avian pathogenic E. coli (APEC) to cells and significantly reduces APEC virulence by regulating transcription of virulence genes.[PhoP; PhoQ] (Mus musculus) PubMed

 16753.

Here, by means of atomistic molecular dynamics simulations and hybrid quantum/classical calculations, the mechanisms that determine the E(0) shift of two azurin mutants with high potential shifts are unravelled. [azurin] (Mus musculus) PubMed

 16754.

Quantitative mass spectrometry identified alpha-toxin (Hla) and leukocidin AB (LukAB) as critical molecules secreted by S. aureus biofilms that inhibit murine macrophage phagocytosis and promote cytotoxicity [LuKAB; Hla] (Mus musculus) PubMed

 16755.

Kingella kingae Knh and the Aggregatibacter aphrophilus EmaA trimeric autotransporter proteins are N-glycosylated by novel homologues of the Haemophilus influenzae HMW1C glycosyltransferase.[EmaA]. (Mus musculus) PubMed

 16756.

Kingella kingae Knh and the Aggregatibacter aphrophilus EmaA trimeric autotransporter proteins are N-glycosylated by novel homologues of the Haemophilus influenzae HMW1C glycosyltransferase [Knh]. (Mus musculus) PubMed

 16757.

gp15 and gp16 can refold from a partially denatured state in vitro, and that gp15 interacts with gp16 to form a spiral ring structure.[gp15] (Mus musculus) PubMed

 16758.

In this in vivo formation assay, cells expressing only the CsoS2 isoform B were capable of producing intact carboxysomes, while those with only the A isoform were not.[CsoS2] (Mus musculus) PubMed

 16759.

The human PHR1, a PH domain-containing protein with low expression in the heart and high expression in the brain, interacts with coxsackievirus B3 VP1, a major structural protein of coxsackievirus B3. (Mus musculus) PubMed

 16760.

ARID3, an AT-rich Interaction Domain-containing protein, is required for shoot meristem development in rice.[ARID3] (Mus musculus) PubMed

 16761.

a novel role of miR-142-3p in maintaining normal neutrophil development and maturation. (Mus musculus) PubMed

 16762.

ccrAB expression and SCCmec excision is modulated by an inverted repeat element and SarS in methicillin-resistant Staphylococcus aureus. [ccrA], [ccrB], [SarS] (Mus musculus) PubMed

 16763.

The quantitative expression, together with the in vivo characterization of the promoter region reveals that GhAO-like1 has a flower- and fruit-specific expression pattern. [GhAO-like1] (Mus musculus) PubMed

 16764.

structural and functional data that reveal an unexpected mode of c-di-GMP recognition that is associated with major conformational rearrangements in FleQ, is reported.[FleQ] (Mus musculus) PubMed

 16765.

These findings implicate WigKR as a regulator of cell wall synthesis that controls cell wall homeostasis in response to antibiotics and likely during normal growth as well.[WigK, WigR] (Mus musculus) PubMed

 16766.

The role of MRG702 in the brassinosteroid (BR) pathway and in controlling flowering time in rice is to function as a reader protein to decipher methylation information. [MRG702] (Mus musculus) PubMed

 16767.

PI5P4Kbeta is the missing GTP sensor and that GTP concentration functions as a metabolic cue via PI5P4Kbeta.[PI5P4Kbeta] (Mus musculus) PubMed

 16768.

Unlike the DNA vaccine, the administration of recombinant OmpL37 induced a strong IgG antibody response. When individually administrated, both formulations stimulated a TNF-a mediated inflammatory response (Mus musculus) PubMed

 16769.

Expression of LEP mRNA in granular and Purkinje cells of the cerebellum, anterior pituitary, and in embryonic limb buds, somites, and branchial arches suggests roles in adult brain control of energy balance and during embryonic development. (Mus musculus) PubMed

 16770.

Results indicated that TcPho91 is a phosphate sodium symporter involved in Pi homeostasis in T. cruzi.[TcPho91]. (Mus musculus) PubMed

 16771.

D101 is an important amino acid for the transcription activity of AttJ and the transcription of attJ is regulated by a negative feedback loop.[AttJ]. (Mus musculus) PubMed

 16772.

study demonstrated that a C-terminal protease called Tsp degrades TcpP to form TcpP*, which is then acted upon by YaeL; cleavage by Tsp occurs in the periplasmic domain of TcpP and requires residues TcpPA172 and TcpPI174 for wild-type activity [TcpP,Tsp] (Mus musculus) PubMed

 16773.

Taken together, these data suggest that while both HA and PB2 are important for viral replication, only the pandemic 1918 virus PB2 exacerbates lung damage in mice infected with a reassortant 1918-like avian virus.[PB2] (Mus musculus) PubMed

 16774.

Phospholipid binding site is localized at the N-terminal four helical bundle structure (1-93 domain).[TcsL] (Mus musculus) PubMed

 16775.

Data suggest that type VII secretion proteins EssB, EssC, and EsaA individually form homomeric complexes; surprisingly, these components of the secretion system appear unable to interact with each other or with EssA protein. [EssB, EssC, and EsaA] (Mus musculus) PubMed

 16776.

Taken together, our data demonstrate that miR-625 suppresses cell proliferation and migration by targeting HMGA1 and suggest miR-625 as a promising prognostic biomarker and a potential therapeutic target for breast cancer. (Mus musculus) PubMed

 16777.

Salmonella Typhimurium L-asparaginase, causes suppression of activation-induced MTOR signaling, autophagy, Myc expression, L-lactate secretion and of cellular processes and pathways involved in protein synthesis, metabolism, and immune response. ansA. (Mus musculus) PubMed

 16778.

role for ZmREM6.3 in quantitative disease resistance to several diseases [ZmREM6.3] (Mus musculus) PubMed

 16779.

In glycoprotein folding process of A. oryzae, TigA plays a similar role as ERp57 in mammalian cells, as a partner protein of calnexin. [TigA] (Mus musculus) PubMed

 16780.

crystal structure of MraY from Aquifex aeolicus in complex with its naturally occurring inhibitor, muraymycin D2 [MraY] (Mus musculus) PubMed

 16781.

Mre11 together with Exo1, but without the help of Sgs1, promotes meiotic double-strand break end resection in Tetrahymena. [Mre11] (Mus musculus) PubMed

 16782.

The accumulation of RecA in mitochondria of the Y. lipolytica recombinant strain bearing the pQ-SRUS construct has been shown by immunoblotting of purified mitochondrial preparations. (Mus musculus) PubMed

 16783.

The authors propose that during rabies virus infection, viral phosphoprotein P binds to ribosomal protein L9 that translocates from the nucleus to the cytoplasm, inhibiting the initial stage of viral transcription.[P] (Mus musculus) PubMed

 16784.

Data show the structure and characterization of Bd3179 found localized in the periplasme. It is a nucleoside diphosphate sugar hydrolase with high degree of sequence and structural similarity to a canonical ADP-ribose hydrolase. [Bd3179] (Mus musculus) PubMed

 16785.

Treki1 plays a key role in growth and development and in the maintenance of cell wall integrity in T. reesei.[Eki1]. (Mus musculus) PubMed

 16786.

It was established that the main contribution in acceleration of the.seedling-heading time is determined by a dominant VRN-A1a allele, while the VRN-A1b allele, on the contrary, determines later plant heading (Mus musculus) PubMed

 16787.

S. Typhimurium sRNA SroC modulates the flagellar synthesis by down-regulating the expression of flhBAE and fliE genes.[SroC]. (Mus musculus) PubMed

 16788.

Deficiency in the mfa4 gene decreased, but did not eliminate, expression of Mfa1 fimbriae. complementation of mfa4 restored expression of structurally intact and functional Mfa1 fimbriae. Mfa4. (Mus musculus) PubMed

 16789.

three-dimensional backbone structure of Ail determined in decyl-phosphocholine (DePC) micelles by NMR spectroscopy, is reported.[Ail] (Mus musculus) PubMed

 16790.

Here we describe the X-ray structure of the precursor mimic of Bacillus licheniformis gamma-glutamyl transpeptidase, obtained by mutating catalytically important threonine to alanine (T399A-BlGT) (Mus musculus) PubMed

 16791.

OsCMT3a-mediated non-CG DNA methylation plays a critical role in development and in the suppression of a wide spectrum of transposable elements.[CMT3a] (Mus musculus) PubMed

 16792.

RpoN1 and RpoN2 proteins are not functionally equivalent or interchangeable in R. solanacearum GMI1000. [RpoN1], [RpoN2] (Mus musculus) PubMed

 16793.

Lr13 and one particular Ne2m allele may be the same leaf rust resistance gene [Lr13] (Mus musculus) PubMed

 16794.

Rice HISTONE MONOUBIQUITINATION1 (OsHUB1) and OsHUB2 function as E3 ligases in H2Bub1, are involved in late anther development in rice. oshub mutants exhibit abnormal tapetum development and aborted pollen in postmeiotic anthers. [OsHUB1; OsHUB2] (Mus musculus) PubMed

 16795.

TcUBP1 is tightly associated with condensed cytoplasmic mRNA granules in starvation. Conversely, under high nutrient/low density-growing conditions, TcUBP1 ribonucleoprotein (RNP) complexes are lax and permeable to mRNA degradation and disassembly.[UBP1] (Mus musculus) PubMed

 16796.

Deletion of either Cdf31or Cdf33 resulted in increased zinc retention.[Cdf31, Cdf33] (Mus musculus) PubMed

 16797.

Pm1.1 is a dominantly inherited powdery mildew resistance major-effect QTL [Pm1.1] (Mus musculus) PubMed

 16798.

The presented data suggest that PfWLP1 supports the stability of adhesion protein complexes of the plasmodial blood stages.[PfWLP1] (Mus musculus) PubMed

 16799.

Taken together, these results suggest that Atg8 and the Atg8 conjugation pathway have some roles in the biogenesis of endosomes and phagosomes in this primitive eukaryote. (Mus musculus) PubMed

 16800.

These data suggest that the serum resistance-associated protein (SRA)/trypanolytic factor interaction is intracellular, with the concentration within the endosomes potentially crucial for ensuring a high efficiency.[SRA] (Mus musculus) PubMed

 16801.

Ni(2+) is directly involved in the derepression of the AdcR regulon via the Zn(2+)-dependent repressor AdcR, and has an opposite effect on the expression of the AdcR regulon compared to Zn(2+).[AdcR] (Mus musculus) PubMed

 16802.

The intrinsically disordered C-terminal arms are relatively collapsed around the tetrameric oliginucleotide binding core and collapse further upon ssDNA binding.[SSB] (Mus musculus) PubMed

 16803.

Phylogenetic analysis of HCV subgenotypes in patients from Sichuan province in China based on the NS5B region. (Mus musculus) PubMed

 16804.

Rice SWI/SNF2 ATPase gene BRHIS1 is downregulated in response to the rice blast fungal pathogen or to the defense-priming-inducing compound BIT (1,2-benzisothiazol-3(2h)-one,1, 1-dioxide).[BRHIS1]. (Mus musculus) PubMed

 16805.

TbIC138 has a direct, or primary, effect on the flagellar beat, whereas detachment is a secondary phenotype of TbIC138 knockdown. IC138. (Mus musculus) PubMed

 16806.

adsorption of zinc ions to the bacterial cell surface increases cell wall cohesion and favors the projection of elongated SasG proteins away from the cell surface, thereby enabling zinc-dependent homophilic bonds between opposing cells.[SasG] (Mus musculus) PubMed

 16807.

Data show the mapping cloning of rice blast Magnaporthe oryzae gene AvrPib, which confers avirulence to host rice carrying resistance gene Pib: [Pib] (Mus musculus) PubMed

 16808.

the first high-resolution crystal structure of an erythrocyte-binding domain from PvRBP2a, solved at 2.12 A resolution, is reported.[PvRBP2a] (Mus musculus) PubMed

 16809.

Data show the map-based cloning of rice blast Magnaporhte oryzae gene AvrPib, which confers avirulence to host rice carrying resistance gene Pib: [AvrPib] (Mus musculus) PubMed

 16810.

FLP-13 and other neuropeptides signal through FRPR-4 and other receptors to regulate locomotion posture and behavioral quiescence.[FRPR-4] (Mus musculus) PubMed

 16811.

NopC can be considered a Rhizobium-specific effector secreted by S. fredii HH103.[NopC] (Mus musculus) PubMed

 16812.

results of the study suggested that Mycoplasma gallisepticum triosephosphate isomerase plays an important role in the metabolism and closely related to the M. gallisepticum pathogenicity.[triosephosphate isomerase]. (Mus musculus) PubMed

 16813.

the X-ray crystal structure of Ape1 at 2.5 A resolution and reveal its dodecameric architecture consisting of dimeric and trimeric units, which associate to form a large tetrahedron.[Ape1] (Mus musculus) PubMed

 16814.

the results provide a quantitative framework for understanding the postinitiation roles of sigma(70) during transcription.[sigma70] (Mus musculus) PubMed

 16815.

Although in the absence of stress, OsDREB1B gene expression was not regulated by light, given previous reports, it remains possible that OsPIF14 has a role in light modulation of stress responses (Mus musculus) PubMed

 16816.

groEL overexpression is costly to large populations evolving in the laboratory, leading to groE expression decline within 66 generations.[groE, groL] (Mus musculus) PubMed

 16817.

TIM-1 and TIM-4 serve as costimulatory molecules required for the full activation of adaptive humoral immunity in zebrafish (Mus musculus) PubMed

 16818.

Over expression of efflux pump genes acrAB-tolC perhaps played an important role in decreased ciprofloxaxin susceptibility under simulated microgravity. (Mus musculus) PubMed

 16819.

This study showed that ribosomal protein S3 (RPS3) dimerizes and is imported into the nucleus with its N-domain in a rotated conformation and associated with the chaperone Yar1.[RPS3; Yar1] (Mus musculus) PubMed

 16820.

functionally characterized MutYs from Lactobacillus brevis and Entamoeba histolytica as representative members from each clades, and found that both enzymes are active adenine glycosylases [MutY] (Mus musculus) PubMed

 16821.

functionally characterized MutYs from Lactobacillus brevis and Entamoeba histolytica as representative members from each clades, and found that both enzymes are active adenine glycosylases [MutY] (Mus musculus) PubMed

 16822.

(UDP-Galactopyranose mutase)The crystal structure of a covalent intermediate in the UDP-galactopyranose mutase reaction was identified. (Mus musculus) PubMed

 16823.

cydAB was able to catalyse O2 consumption and was involved in peroxide and superoxide resistance, and dioxygen tolerance [cydAB] (Mus musculus) PubMed

 16824.

study examined the effect of different redox-active compounds on growth of S. coelicolor, correlating their physiological effect with the sensitivity of ScSoxR toward them; investigated the contribution of specific amino acid residues around the [2Fe-2S] site to determining differential sensitivity and redox potential [SoxR] (Mus musculus) PubMed

 16825.

SodCI non-covalently binds peptidoglycan. SodCI binds to Salmonella and Bacillus peptidoglycan, but not peptidoglycan from Staphylococcus.[SodCI]. (Mus musculus) PubMed

 16826.

BacE and BacF are essential for motility. They are needed for the establishment of flagellar hook- and filament structures, but not basal bodies. BacF assemblies are static; BacE are mobile. BacE. BacF. (Mus musculus) PubMed

 16827.

Srr2 is a multifaceted adhesin used by the ST-17 clone to hijack ligands of the host coagulation system, thereby contributing to bacterial dissemination and invasiveness, and ultimately to meningitis. (Mus musculus) PubMed

 16828.

SalA possesses a DNA-binding domain (residues 1-60), which binds to the promoter region of scoC, it depends on the presence of ATP and is stimulated by phosphorylation of SalA at tyrosine 327. [ScoC protein] (Mus musculus) PubMed

 16829.

PcrA is a dynamic structure with domain movements that correlate with particular functional states.[Pcra] (Mus musculus) PubMed

 16830.

Trm1 crystal structure reveals next to the catalytic SPOUT domain also N- and C-terminal domains and provides crucial insights in the tRNA binding mechanism.[Trm1] (Mus musculus) PubMed

 16831.

NMR analysis of MutY structure reveal its mechanism for adenine removal with retention of stereochemistry.[MutY] (Mus musculus) PubMed

 16832.

Results demonstrated that high beta-lactam resistance can be transferred from S. oralis into S. pneumoniae, involving four components important for peptidoglycan biosynthesis: including MurE.[MurE]. (Mus musculus) PubMed

 16833.

The study assigns a key regulatory role to FaGAMYB in the initiation of strawberry receptacle ripening and acting upstream of the known regulator abscissic acid.[FaGAMYB] (Mus musculus) PubMed

 16834.

These data reveal that DNA damage response triggered by murine gammaherpesvirus 68 infection promote p53 activation. However, the virus-encoded LANA and SOX homologs are capable of limiting the potential consequences of p53 function.[muSOX] (Mus musculus) PubMed

 16835.

Nanomechanical Stability of a Redox Protein Active Site and Its Dependence upon Metal Binding [azurin] (Mus musculus) PubMed

 16836.

Structural signatures in Vibrio cholerae cytolysin implicated for its functional interactions with the membrane lipid components, drive the subsequent steps of the oligomeric beta-barrel pore-formation and cytotoxic responses. [cytolysin] (Mus musculus) PubMed

 16837.

High-resolution crystal structures of TgAMA4 in the apo and TgRON2L1-bound forms reveal an unexpected architecture and assembly mechanism relative to previously characterized AMA-RON2 complexes.[RON2, AMA4] (Mus musculus) PubMed

 16838.

genetic mapping of spot blotch resistance gene Sb3 [Sb3] (Mus musculus) PubMed

 16839.

Aspergillus nidulans galR, xlnR and araR epistatically interact in regulating D-galactose and L-arabinose release and catabolism gene expression. [galR], [xlnR], [araR] (Mus musculus) PubMed

 16840.

Results suggest that Salmonella effector SseK3 binding to host tripartite motif-containing 32 protein (TRIM32) in the inhibition of nuclear factor kappa B (NF-kappaB) activation: [SseK3] (Mus musculus) PubMed

 16841.

Detailed picture of the active site of Naegleria Tet-like protein,(NgTet1), at individual stages of the reaction cycle (NgTet1). (Mus musculus) PubMed

 16842.

Data shows that the beta-propeller domains of the Erb1 and Ytm1 proteins interact in a novel manner that leads to high-affinity binding (Erb1 and Ytm1). (Mus musculus) PubMed

 16843.

CsVosA may affect virulence of the fungus by regulating the expression of the genes for nonribosomal peptide synthetases, as well as other genes directly or indirectly involved in virulence.[CsVosA] (Mus musculus) PubMed

 16844.

Multidrug transporters (CDR1 and MDR1) and alterations in sterol biosynthesis (ERG11) contribute to azole antifungal resistance in candida parapsilosis. [CDR1], [MDR1], [ERG11] (Mus musculus) PubMed

 16845.

The helminth T2 RNase omega1 promotes metabolic homeostasis in an IL-33- and group 2 innate lymphoid cell-dependent mechanism. (Mus musculus) PubMed

 16846.

GhFPF1 might influence the timing of the floral transition independently of shade-mediated early flowering.[GhPFP1] (Mus musculus) PubMed

 16847.

The study found that truncation of the DnaA N-terminal completely abolishes the co-operative transformation between the high and low occupancy states (I and II respectively) without affecting the membrane binding. [DnaA] (Mus musculus) PubMed

 16848.

Ser5-P and Ser2-P occur throughout the length of Rpb1 C-Terminal Domain and are far more abundant than other phosphorylation sites.[Rpb1] (Mus musculus) PubMed

 16849.

Study provided insight into the autoregulation of ZEB2 expression by alternative promoter usage and a feedback loop during zearalenone production.[ZEB2]. (Mus musculus) PubMed

 16850.

The immunofluorescence assay results show that PfBlm is expressed in all the stages of intraerythrocytic development of the P. falciparum 3D7 strain. In some stages of development in addition to nucleus PfBlm also localizes in the cytoplasm (Mus musculus) PubMed

 16851.

study describes the crystal structures of FabG; YpFabG crystallised in two different crystal forms, one diffracting to 2.50 A, and the other to 2.85 A [FabG] (Mus musculus) PubMed

 16852.

The BetP possesses a 60-amino acid (aa)-long negatively charged N-terminal domain, which is predicted to adopt a partly helical fold affecting osmoregulation by an unknown mechanism. (Mus musculus) PubMed

 16853.

cloning and expression of a putative, non-canonical Ras-like G protein; data suggest that the putitative, Ras-like G-protein might be involved in a non-canonical signaling pathway in Plasmodium [Ras-like GTPase] (Mus musculus) PubMed

 16854.

FKBP12-1 is the key mediator of FK506-binding to calcineurin. [fkbp12-1] (Mus musculus) PubMed

 16855.

CheZ(HP) localization depends on the chemotaxis regulatory protein ChePep, and reciprocally, ChePep requires CheZ(HP) for its polar localization. These proteins interact directly. [CheZ, Helicobacter pylori] (Mus musculus) PubMed

 16856.

RpoS is important in resistance to multiple stressors-including H2O2, acid, osmotic and heat shock-in Y. pseudotuberculosis. In addition, our study showed that RpoS not only modulates the expression of T6SS but also regulates flagellum formation.[RpoS]. (Mus musculus) PubMed

 16857.

molecular cloning of L-methionine gamma-lyase from Streptomyces avermitilis (Mus musculus) PubMed

 16858.

LptA specifically interacts with the Lipid A from Anabaena sp. PCC 7120 only, while LptD binds to Lipid A isolated from Escherichia coli as well [LptA & LptD] (Mus musculus) PubMed

 16859.

Study shows the molecular cloning and characterization of CenC protein from Clostridium thermocellum. It is a thermostable endoglucanase belonging to the glycoside hydrolase family 9 with cellulose binding domains (CBDs) and GH9 catalytic domain. [CenC] (Mus musculus) PubMed

 16860.

The domain responsible for P3-P3 interaction was mapped to amino acids 15-30 at the N-terminal region of P3. [P3] (Mus musculus) PubMed

 16861.

The levels of photosynthetic pigments and abscisic acid (ABA) were altered in Potato virus Y (PVY)-infected tobacco. PVY HC-Pro was found to promote the synthase activity of NtDXS (tobacco chloroplast protein 1-deoxy-D-xylulose-5-phosphate synthase). (Mus musculus) PubMed

 16862.

The activation kinetics of Kv7.2 is far slower than that of Kv1.1 during structural axon initial segment plasticity. [Kv7.2] (Mus musculus) PubMed

 16863.

Ralstonia solanacearum encodes two 3-ketoacyl-ACP reductases that both FabG1 and FabG2 have functions in fatty acid synthesis.[FabG1 and FabG2] (Mus musculus) PubMed

 16864.

a model that maps all functionally important structural features for yeast Rmi1 and structure-prediction-based alignment with the recently established crystal structure of the N-terminus of human Rmi1, is proposed.[Rmi1] (Mus musculus) PubMed

 16865.

In conclusion, these results suggest that Bm64 plays an important role in budded virus production and per os infection, but is not required for viral DNA replication or occlusion-derived virus maturation.[Bm64] (Mus musculus) PubMed

 16866.

OtpR regulated many Brucella virulence factors essential for B. melitensis intracellular survival.(OtpR) (Mus musculus) PubMed

 16867.

Report biased expression of human interferon alpha-2b and Escherichia coli methionine amino peptidase genes under control of single promoter in E. coli. (Mus musculus) PubMed

 16868.

Results show that YnaI has a seven-fold symmetric organization similar to that of MscS, with an almost identical organization of the C-terminal cytosolic domain but with larger membrane domain, consistent with its N-terminal extension. [YnaI] [MscS] (Mus musculus) PubMed

 16869.

PmrA variants with altered interface residues suggest that the interface is not crucial for supporting gene expression. [PmrA] (Mus musculus) PubMed

 16870.

The study reports ATP-independent reduction of CO2 to hydrocarbons by a reaction system comprising Eu(II) DTPA and the vanadium nitrogenase. [vanadium nitrogenase] (Mus musculus) PubMed

 16871.

AphA belongs to the class B nonspecific acid phosphatases. [AphA] (Mus musculus) PubMed

 16872.

TagI and mfd genes are required for virulence of non-typeable Haemophilus influenza.[TagI, mfd ] (Mus musculus) PubMed

 16873.

A 15 kDa protein with anti-inflammatory properties produced by F. prausnitzii inhibits the NF-kappaB pathway in intestinal epithelial cells and prevents colitis in an animal model. [microbial anti-inflammatory molecule ZP 05614546.1] (Mus musculus) PubMed

 16874.

The pla gene, encoding plasminogen activator, is not specific to Yersinia pestis, but is also present in Escherichia coli strain FHI29. [pla] (Mus musculus) PubMed

 16875.

The pla gene, encoding plasminogen activator, is not specific to Yersinia pestis, but is also present in Citrobacter koseri. [pla] (Mus musculus) PubMed

 16876.

BnDof5.6 is required for embryo development and fatty acids synthesis in canola. [BnDof5.6] (Mus musculus) PubMed

 16877.

The second stage confirmed significant SNPs in a locus encoding two Toll-family proteins. RNAi-mediated gene silencing and infection challenge revealed that TOLL 11 protects mosquitoes against P. falciparum infection (Mus musculus) PubMed

 16878.

crystal structures of SghA and SghR at 1.9 and 2.1 A resolution, respectively [SghA & SghR] (Mus musculus) PubMed

 16879.

crystal structure of substrate-free form of RizA at 2.8 A resolution [RizA] (Mus musculus) PubMed

 16880.

crystal structure of nonstructural protein 15 mutant from Human coronavirus 229E [nsp15] (Mus musculus) PubMed

 16881.

Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems. (Mus musculus) PubMed

 16882.

These observations demonstrate that TgLCAT influences the outcome of an infection, presumably by facilitating replication and egress depending on the developmental stage of the parasite. (Mus musculus) PubMed

 16883.

The studies described here investigate the role for BfpI, BfpJ, and BfpK, in the structure and function of bundle-forming pili in enteropathogenic E. coli.[BfpI; BfpJ;BfpK] (Mus musculus) PubMed

 16884.

Deletion mutagenesis of carB gene resulted in reduced abilities in swimming on soft solid media and in forming biofilm on polystyrene microtiter plates.[carB] (Mus musculus) PubMed

 16885.

OsFdC2 plays an important role in photosynthetic rate and development of heading date by regulating electron transfer and chlorophyll content in rice [OsFdC2] (Mus musculus) PubMed

 16886.

Report inhibition of E.coli GlpG using peptide aldehydes is non-competitive and substrate does not contact the catalytic center. (Mus musculus) PubMed

 16887.

Efb can play an immunoregulatory role via inhibition of P-selectin-PSGL-1-dependent formation of platelet-leukocyte complexes. (Mus musculus) PubMed

 16888.

Deletion of yhcX eliminated SQR9-mediated increases in root surface area, likely by reducing IAA-stimulated lateral root growth. [yhcX] (Mus musculus) PubMed

 16889.

EF4 induces back-translocation by disengaging the tRNA's CCA end from the peptidyl transferase center of the translating ribosome. [EF4] (Mus musculus) PubMed

 16890.

Study determined cryo-electron microscopy structures of CorA in the Mg(2+)-bound closed conformation and in two open Mg(2+)-free states at resolutions of 3.8, 7.1, and 7.1 A, respectively. (Mus musculus) PubMed

 16891.

Pns4 of rice dwarf virus is essential for viral infection and replication in insect vector.[Pns4] (Mus musculus) PubMed

 16892.

The P proteins from the rabies virus street strains 1088 and HCM-9 significantly inhibited I-kappa B kinase (IKK)-inducible IRF-3-dependent IFN-beta promoter activity.[P protein] (Mus musculus) PubMed

 16893.

Influenza H1N1 virus NS2 protein inhibits the production of interferon gamma in lung tissues. (Mus musculus) PubMed

 16894.

Deep-sequencing of R. erythropolis enhanced variants allowed identification of a point mutation in a key-transcriptional factor QsdR which regulates QsdA and activates the QS-signal degradation pathway. QsdR. (Mus musculus) PubMed

 16895.

The loss of Aas accelerated photodamage of PSII but did not affect the repair process of PSII, indicating that PSII is destabilized in the mutant. Thus, Aas is essential for acclimation of the cyanobacterium to high-light conditions. [Aas] (Mus musculus) PubMed

 16896.

These results strongly suggest the involvement of FLVA and FLVB proteins in alternative electron transport. [FLVA; FLVB] (Mus musculus) PubMed

 16897.

Escherichia coli YddG exports various amino acids [YddG] (Mus musculus) PubMed

 16898.

identification of a new indispensable bacterial replication origin element composed of a repeating trinucleotide motif called the DnaA-trio, which functions to stabilize DnaA filaments on a single DNA strand [DnaA] (Mus musculus) PubMed

 16899.

crystal structure of S. novella YddG at 2.4 A resolution reveals a new membrane transporter topology, with ten transmembrane segments in an outward-facing state [YddG] (Mus musculus) PubMed

 16900.

Results show that LexA is not only a regulator of DNA damage but also controls many biological functions associated with virulence in Clostridium difficile. [LexA] (Mus musculus) PubMed

 16901.

Study provides atomistic details of DNA polymerase I closing mechanism, proposes sequence of events in prechemistry of its active site assembly, and identifies a conserved histidine as a potential proton acceptor to initiate catalysis. [DNA pol I] (Mus musculus) PubMed

 16902.

Study revealed the 3D structure of cdc123 and its binding to ATP. Also, the docking model suggests that its C-terminal domain is involved in the assembly process of eIF2g to eIF2a. [cdc123] (Mus musculus) PubMed

 16903.

The data point to InpA as an efficient "albuminase" with the ability to degrade the minor fraction of haem-bound albumin in plasma.[InpA] (Mus musculus) PubMed

 16904.

The genome-specific primers developed will enable future characterization of natural and induced variation in EPSPS sequence and expression. (Mus musculus) PubMed

 16905.

findings identified and experimentally confirmed the potential of PvMSP9E795-A808 as an immunogenic linear B cell epitope within the P. vivax malaria vaccine candidate PvMSP9 and support its inclusion in future subunit vaccines. (Mus musculus) PubMed

 16906.

MSP1 induces a high degree of cell death in plants, which might be essential for its virulence. Moreover, rice can recognize MSP1, resulting in the induction of pathogen-associated molecular pattern-triggered immunity. [MSP1] (Mus musculus) PubMed

 16907.

results were consistent with the PKA pathway contributing to phosphorylated ribosomal protein S6 regulation by acting either upstream of, or parallel to the TOR pathway.[Ribosomal protein S6]. (Mus musculus) PubMed

 16908.

miR-181a/b-1-dependent modulation of T cell selection is not critically required for innate development of gammadelta NKT cells or of any other gammadelta T cell subtypes. (Mus musculus) PubMed

 16909.

In BSP-II-treated hybridoma cells, regulated genes were involved in cytokine-cytokine receptor interactions, T cell receptor signaling pathway, and pathway in cancer. BSP-II reduced tumor cells proliferation and stimulated p53 expression. [BSP-II] (Mus musculus) PubMed

 16910.

SPOIIIE plays an important role in the sporulation and vegetative growth. [SPOIIIE] (Mus musculus) PubMed

 16911.

Characterized the functioning of a homologous Epsilon/Zeta system (designated SezAT) encoded by SsPI-1 of epidemic S. suis. Data show that SezAT is a functional TA system, with SezT as the toxin and SezA as its cognate antitoxin.[SezA SezT] (Mus musculus) PubMed

 16912.

AOX1 subunits of the structure reported here harbor a modified flavin adenine dinucleotide, which contains an arabityl chain instead of a ribityl chain attached to the isoalloxazine ring (Mus musculus) PubMed

 16913.

The rel1 dominant mutant phenotype is caused by the activation of the REL1 gene, which encodes a novel unknown protein. The downregulation of the REL1 gene in the rel1 dominant mutant restored the phenotype of this dominant mutant.[REL1] (Mus musculus) PubMed

 16914.

Copy Number Variation of Cytokinin Oxidase Gene Tackx4 Associated with Grain Weight and Chlorophyll Content of Flag Leaf in Common Wheat [Tackx4] (Mus musculus) PubMed

 16915.

the secreted natto phytase was purified and found to remove up to 3 phosphates from IP6 (Mus musculus) PubMed

 16916.

This is a strategic structural study of two homologous sugar aminotransferases (Micromonospora echinospora CalS13 and Escherichia coli WecE) that utilize identical substrates but differ in their stereochemistry of aminotransfer. [WecE] (Mus musculus) PubMed

 16917.

Intramembrane Aspartyl Protease (IAP) can hydrolyze the angiotensinogen sequence, a substrate for the soluble aspartyl protease renin. [Intramembrane Aspartyl Protease] (Mus musculus) PubMed

 16918.

study explores the interaction of NDH-2 with substrates and present its biochemical, structural and functional characterization [NDH-2] (Mus musculus) PubMed

 16919.

3 isozymes of glyceraldehyde oxidoreductase (GAOR1, GAOR2 and GAOR3) were isolated. They are composed of a molybdo-pyranopterin subunit (L), a flavin subunit (M), and an iron-sulfur subunit (S), forming an LMS hetero-trimer unit. GAOR1. GAOR2. GAOR3. (Mus musculus) PubMed

 16920.

The VtlR system may represent a common genetic regulatory mechanism required for efficient host-bacterium interactions among the alpha-proteobacteria [VtlR] (Mus musculus) PubMed

 16921.

Glutamate dehydrogenase is required by Mycobacterium bovis BCG for resistance to cellular stress. [Glutamate dehydrogenase] (Mus musculus) PubMed

 16922.

This study identified SuhB as a novel ribosome associated protein that is involved in modulating ribosome activity.[SuhB]. (Mus musculus) PubMed

 16923.

study provides experimental evidence showing that the conserved cell wall protein CwpV from C. difficile has antiphage activity.[CwpV]. (Mus musculus) PubMed

 16924.

Notably, one accession, Phulba, had a NAL1 allele encoding only the N-terminal, or one-fourth, of the wild-type peptide. (Mus musculus) PubMed

 16925.

Data suggest that C-terminal domain of LeuRS is indispensable in substrate specificity, allowing LeuRS to recognize non-cognate C. albicans RNASer (CAG) and cognate C albicans RNALeu leading to CUG codon reassignment. [LeuRS, leucyl-tRNA synthetase] (Mus musculus) PubMed

 16926.

Our results suggest that CENP-T particles occupy linkers between CENP-A nucleosomes and that classical regional centromeres differ from other centromeres by the absence of CENP-A nucleosome positioning (Mus musculus) PubMed

 16927.

OsANN1-knockdown plants were more sensitive to heat and drought stresses, whereas OsANN1-overexpression lines showed improved growth with higher expression of OsANN1 under abiotic stress. [ANN1] (Mus musculus) PubMed

 16928.

Data (including data from studies in knockout mice) suggest causative role for collagen(V)alpha1 hypersensitivity/autoimmunity in pathogenesis of atherosclerosis; immune tolerance and reduction of plaque burden are dependent on interleukin 35. [IL35] (Mus musculus) PubMed

 16929.

Results suggest that FliL is localized along with the stator in order to support the motor functioning for swimming at high load conditions by maintaining the stator assembly[FliL] (Mus musculus) PubMed

 16930.

miRX27 plays a role in the nicotine biosynthesis. [miRX27] (Mus musculus) PubMed

 16931.

WCBP1 is the putative candidate gene of YrL693, which was involved in leaf senescence and photosynthesis related to plant responses to stripe rust infection during the grain-filling stage.[WCBP1] (Mus musculus) PubMed

 16932.

genetic and biological data show that Wos1-mediated Wor1 SUMOylation contributes to the regulation of CO(2) -induced white to opaque switching as well as heritable maintenance of the opaque cell type[Wor 1; WOS1]. (Mus musculus) PubMed

 16933.

Results suggest that the ATP-dependent polar localization of FlhG is crucial for its ability to downregulate the number of polar flagella.[FlhG]. (Mus musculus) PubMed

 16934.

U11 is an essential gene for virus growth and propagation. [U11] (Mus musculus) PubMed

 16935.

Estimation of the Binding Free Energy of AC1NX476 to HIV-1 Protease Wild Type and Mutations Using Free Energy Perturbation Method. (Mus musculus) PubMed

 16936.

Fusarium graminearum Hex1 protein binding to untranslated regions of the RNA of Fusarium graminearum virus 1 correlates with increased accumulation of both strands of viral RNA. [Hex1] (Mus musculus) PubMed

 16937.

P3 proteins function as a movement protein.[p3] (Mus musculus) PubMed

 16938.

Polymorphisms in B Cell Co-Stimulatory Genes Are Associated with IgG Antibody Responses against Blood-Stage Proteins of Plasmodium vivax. (Mus musculus) PubMed

 16939.

ligand binding mechanism [Bbp] (Mus musculus) PubMed

 16940.

Our results reveal an S. aureus Cas9 that is effective for a variety of genome engineering purposes, including paired nickase approaches and all-in-one delivery of Cas9 and multiple gRNA expression cassettes with AAV vectors (Mus musculus) PubMed

 16941.

the phosphate-starvation responsive strigolactone biosynthesis gene MtD27 is also rapidly induced by rhizobium lipo-chitooligosaccharide signals.[MtD27] (Mus musculus) PubMed

 16942.

DIM-1 possesses a binuclear metal center with a 5 (rather than the more usual 4) co-ordinate tri-histidine (Zn1) site and both 4- and 5-co-ordinate Cys-His-Asp- (Zn2) sites observed in the two molecules of the crystallographic asymmetric unit. [DIM-1] (Mus musculus) PubMed

 16943.

FNSI-1 is expressed at significantly higher levels in silks and pericarps and can convert flavanones to flavones. [fnsi-1] (Mus musculus) PubMed

 16944.

Results presented here suggest that receptor-independent adhesion could provide an additional selective advantage to cells that have newly acquired cdi genes.[CdiA]. (Mus musculus) PubMed

 16945.

The tissue specificity of BPH29 is restricted to vascular tissue, the location of brown planthopper (BPH) attack.[BPH29] (Mus musculus) PubMed

 16946.

CreD plays a critical role in the maintenance of envelope integrity. (Mus musculus) PubMed

 16947.

This study demonstrated that culture supernatants of E. coli expressing HlyF induced autophagy in eukaryotic cells.[HlyF] (Mus musculus) PubMed

 16948.

Fdl1 is involved in regulation of cuticle deposition in young seedlings as well as in establishment of a regular pattern of epicuticular wax deposition on the epidermis of young leaves. Lack of Fdl1 action also correlates with developmental defects.[fdl1] (Mus musculus) PubMed

 16949.

We show that PfAlba1 binds to a sub-population of asexual stage mRNAs and fine-tunes the timing of translation. (Mus musculus) PubMed

 16950.

OsAGSW1 plays an important role in seed shape and size of rice by regulating the number of external parenchyma cells and the development of vascular bundles, providing a new insight into the functions of ABC1 genes in plants.[AGSW1] (Mus musculus) PubMed

 16951.

After injection with Vibrio harveyi, 10 studied tissues had a higher expression of IFN-gamma at the first day (1 d); only spleen, muscle, intestine, heart and skin had higher expressions after infected with Cryptocaryon irritans at 1 d. [IFN-gamma] (Mus musculus) PubMed

 16952.

identified acyl acceptor site of L,D-transpeptidase Ldt(fm); 3 residues are reported as critical for stabilisation of the acceptor in the Ldt(fm) active site and proper orientation of the nucleophilic nitrogen for the attack of the acylenzyme carbonyl [L,D-transpeptidase Ldtfm] (Mus musculus) PubMed

 16953.

Hairy and its cofactor Gro mediate the repressive function of juvenile hormone and Met.[Hairy, Groucho, Met] (Mus musculus) PubMed

 16954.

L1 and L2 are also involved in virus superinfection. [L1, L2] (Mus musculus) PubMed

 16955.

TaSKs are proposed to be involved in brassinosteroid signaling.[TaSK1, TaSK2] (Mus musculus) PubMed

 16956.

JMJ704 may be a universal switch controlling multiple genes of the bacterial blight resistance pathway.[JMJ704] (Mus musculus) PubMed

 16957.

Data suggest that for Fno, an NADPH- and coenzyme F420-dependent dimeric enzyme, product release is rate-limiting; kinetic analysis reveals half-site reactivity and negative cooperativity. [Fno, F420-dependent NADP oxidoreductase] (Mus musculus) PubMed

 16958.

Rv3423.1 is a novel histone acetyltransferase that acetylates histone H3 at the K9/K14 positions. [Rv3423.1] (Mus musculus) PubMed

 16959.

While newly identified broad-spectrum amino acid transporters could transport various amino acids into yeast or Arabidopsis cells, ZmAAP4 appeared to have higher efficiencies than ZmVAAT3 in transporting seven out of 22 examined amino acids.[AAP4,VAAT3] (Mus musculus) PubMed

 16960.

BdVgR is the first reported gene expressed in fat body of a nonsocial insect. It may be involved in reuptake of yolk proteins from the hemolymph as an amino acid reservoir or as autocrine regulation of yolk protein expression.[Vg receptor] (Mus musculus) PubMed

 16961.

In this study, we define a novel role for Nug1 in ribosome biogenesis. We show that Nug1 and Dbp10 bind adjacent to each other at a site on the 60S subunit that goes on to form the peptidyl-transferase center (PTC) in the mature ribosome (Mus musculus) PubMed

 16962.

The role of citT and dctA in citrate utilization by E. coli and the effects of their mutation are reported.[citT; dctA] (Mus musculus) PubMed

 16963.

These results highlight that the virulence factor ROP18 in Toxoplasma gondii may contribute to neuronal apoptosis through the endoplasmic reticulum stress-mediated apoptosis pathway.[ROP18] (Mus musculus) PubMed

 16964.

Complete resonance assignments and backbone dynamics were determined for fucose-binding lectin in the sugar-free form and when bound to l-fucose or d-mannose. [fucose-binding lectin] (Mus musculus) PubMed

 16965.

Data suggest that, upon photoactivation, orange/red forms of OCP undergo dramatic conformational changes from perspective of N-terminal and C-terminal domain orientation. [OCP, orange carotenoid protein] (Mus musculus) PubMed

 16966.

The N-terminal pre-A region of Mycobacterium tuberculosis 2/2HbN promotes NO-dioxygenase activity, which is revealed by its crystal structure.[2/2HbN ] (Mus musculus) PubMed

 16967.

knockout of ARP6 led to disruption of microtubule integrity, higher uptake and degradation of virulence proteins, and increased DNA stability inside the cells, all of which resulted in enhanced transformation efficiency.[ARP6] (Mus musculus) PubMed

 16968.

the Rtt101(Mms22) E3 ligase does not induce Mrc1 degradation, but specifically counteracts Mrc1's replicative function.[Rtt101, Mms22, Mrc1] (Mus musculus) PubMed

 16969.

a DEAD-box RNA helicase, TOGR1 (Thermotolerant Growth Required1), prerequisite for rice growth themotolerance, is reported.[TOGR1] (Mus musculus) PubMed

 16970.

These results revealed that the intracellular redox environment is different in hmbBDelta conidia and mycelia from that of hmbB+.[HmbB] (Mus musculus) PubMed

 16971.

His213 and Glu213 in H213E may act as a catalytic base to initiate the substrate deprotonation and facilitate the electrophilic aromatic substitution of 3HB [3HB6H] (Mus musculus) PubMed

 16972.

The A16G AbeS variant displays a substrate-specific hyperactive phenotype. Transport of drugs occurs via an electrogenic nH+/drug+ antiport mechanism. [AbeS] (Mus musculus) PubMed

 16973.

The study uses enhanced density functional modeling to characterize the proton translocation mechanisms to the active site of nitrogenase. [nitrogenase] (Mus musculus) PubMed

 16974.

Data suggest glideosome-associated proteins (GAP40 and GAP50) play critical roles in biogenesis of IMC (inner membrane complex) during intracellular replication/asexual reproduction. [GAP40 and GAP50] (Mus musculus) PubMed

 16975.

exposure to the polyphenol dihydrocoumarin led to defects in several Sirtuin-regulated processes in budding yeast.[Sir2] (Mus musculus) PubMed

 16976.

Mps1(Mph1) kinase-dependent modifications of Mad3 and Mad2 act in a concerted manner to maintain spindle checkpoint arrests.[Mph1, Mad3, Slp1] (Mus musculus) PubMed

 16977.

Results show that Sat does not act as a virulence factor in Escherichia coli Nissle 1917. The role of Sat in intestinal pathogenesis relies on other genetic determinants of the bacteria. [Sat] (Mus musculus) PubMed

 16978.

This study proposes the existence of an interplay between the Hac1p- and calcineurin- controlled networks via a downstream effector molecule of the latter, RTA2, to facilitate survival during endoplasmic reticulum stress in Candida albicans.[RTA2] (Mus musculus) PubMed

 16979.

These results suggested strongly that Fusarium graminearum phospholipase C plays important roles in fungal growth and development. (Mus musculus) PubMed

 16980.

These results indicated that laccase activity and in particular that encoded by lcc2 contributes to toxin metabolism and by extension green mould disease resistance.[lcc2] (Mus musculus) PubMed

 16981.

These findings suggest a novel relationship between miR-3162-3p and beta-catenin and clarify their mechanistic role in asthma etiopathogenesis.[miR 3162] (Mus musculus) PubMed

 16982.

the mutations in the mir-15a/16-1 loci are responsible for decreased expression of this regulatory microRNA leading to B-1 expansion and Chronic Lymphocytic Leukemia development.[Mir 15a] (Mus musculus) PubMed

 16983.

BglC3 is an extracellular endoglucanase required for the full virulence of X. citri subsp. citri [BglC3] (Mus musculus) PubMed

 16984.

These findings suggest that LonA plays a critical role in the environmental survival and virulence of Vibrio cholerae.[LonA] (Mus musculus) PubMed

 16985.

Subsequent in vitro assays demonstrated significant inhibition of Haemonchus contortus larval growth and development in the presence of recombinant galectin-11. (Mus musculus) PubMed

 16986.

expression of AdcAII affects invasiveness of S. pneumoniae in response to available Zn2+ concentrations (Mus musculus) PubMed

 16987.

a bacterial nox gene encoding NADH oxidase is involved in biofilm formation (Mus musculus) PubMed

 16988.

evolutionarily conserved PpASCL gene is needed for proper construction of the spore wall and for normal maturation and viability of moss spores [ppASCL] (Mus musculus) PubMed

 16989.

These results demonstrate that Cap1 in Schizosaccharomyces pombe is a multifunctional protein that functions through interaction with Cap1 itself and other proteins including adenylyl cyclase, actin and Csh3.[Cap1, Csh3] (Mus musculus) PubMed

 16990.

CLR-1, CLR-2, and XLR-1 individually bind to the promoters in their respective regulons that include genes encoding cellulases for CLR-1 and CLR-2 (CLR-1/CLR-2) and genes encoding hemicellulases for XLR-1.[CLR-1, CLR-2, XLR-1] (Mus musculus) PubMed

 16991.

The waaF gene was related with O-antigen synthesis and it was the key gene of O-antigen synthesis pathway. [waaF] (Mus musculus) PubMed

 16992.

ECFsigma5 indirectly inhibits avermectin production by affecting transcription of ave genes.[ECFsigma5] (Mus musculus) PubMed

 16993.

a 91 bp LacI-mediated, negatively supercoiled DNA loop mimicking the DNA loop between the O1 and O3 operators in the lac promoter [LacI] (Mus musculus) PubMed

 16994.

scoC null mutation had little effect on aprE or nprE expression; full effects of scoC or codY null mutations could be seen only in the absence of the other regulator.[scoC, codY] (Mus musculus) PubMed

 16995.

RacA, which is essential for reactive oxygen species (ROS) production in the vesicle as well as differentiation of phialides in Aspergillus fumigatus, is reported.[RacA] (Mus musculus) PubMed

 16996.

structure of Thermobifida fusca DyP-type peroxidase and activity towards Kraft lignin and lignin model compounds [DyP] (Mus musculus) PubMed

 16997.

The MaMADS7 gene role in the regulation of fruit ripening and quality [MaMADS7] (Mus musculus) PubMed

 16998.

FRRP1 probably regulates flowering time and yield potential in rice by affecting histone H2B monoubiquitination, which leads to changes in gene expression in multiple processes. [FRRP1] (Mus musculus) PubMed

 16999.

a second fads2 cDNA was cloned from the liver of rainbow trout and termed fads2b.[Fads2b] (Mus musculus) PubMed

 17000.

[Mte1] Mte1 functions with Mph1 and the associated MHF complex in replication fork repair (Mus musculus) PubMed

 17001.

[Mte1] Mph1 and Mte1 interdependently colocalize at DNA damage-induced foci and dysfunctional telomeres, and MTE1 deletion results in elongated telomeres (Mus musculus) PubMed

 17002.

Knockdown of NtSVP by RNA interference caused elongated pedicels while overexpression resulted in compact inflorescences with much shortened pedicels. An Arabidopsis homologue NtBP-Like (NtBPL) was significantly up-regulated in NtSVP-RNAi plants.[SVP,BPL] (Mus musculus) PubMed

 17003.

Helicobacter pylori CagA interacts with PRK2 and inhibits its kinase activity. (Mus musculus) PubMed

 17004.

Study characterizes the human VAPB-HCV NS5B interaction and reveals that NS5B C-linker is intrinsically disordered in solution but capable of binding the human VAPB-MSP domain which overlaps with those for binding HCV NS5A and human Eph receptors. [NS5B] (Mus musculus) PubMed

 17005.

a dynamic model whereby RovM coordinately regulates the expression of AR3 and T6SS4 in response to the availability of nutrients in the environment was proposed. [RovM] (Mus musculus) PubMed

 17006.

Crystal structure of Xanthomonas AvrRxo1-ORF1, a type III effector with a polynucleotide kinase domain, and its interactor AvrRxo1-ORF2 has been presented. [AvrRxo1] (Mus musculus) PubMed

 17007.

miR-15/16 and CPEB co-regulate cyclin E1 mRNA.[miR-15/16] (Mus musculus) PubMed

 17008.

the CPAF106-212 sequence is homologous to PDZ domains of human tight junction proteins.[CPAF] (Mus musculus) PubMed

 17009.

BsuLigD also has an intrinsic 5'-2-deoxyribose-5-phosphate (dRP) lyase activity located at the N-terminal ligase domain that allows efficient repairing of 2'-deoxyuridine-containing DNA in an in vitro reconstituted Base Excision Repair (BER) reaction (Mus musculus) PubMed

 17010.

TUTOU1 plays an important role in panicle development and actin organization. [TUTOU1] (Mus musculus) PubMed

 17011.

cagA, virB/D complex and vacA genes are expressed in Helicobacter pylori strains originating from patients with gastric diseases [cagA, vacA] (Mus musculus) PubMed

 17012.

Staphylococcus aureus alpha-Hemolysin Gene (hla) genotypic diversity correlates with clonal background but not geographic origin, host source or methicillin-resistance phenotype (Mus musculus) PubMed

 17013.

Structure of ribosomal silencing factor (RSFS) bound to Mycobacterium tuberculosis ribosome has been described. [RSFS] (Mus musculus) PubMed

 17014.

Data show that structural differences between solonamide analogues confer significant differences in interference with accessory gene regulator protein agr: [agr] (Mus musculus) PubMed

 17015.

The interaction between rice ERF3 and WOX11 promotes crown root development by regulating gene expression involved in cytokinin signaling.[ERF3:Os01g58420] (Mus musculus) PubMed

 17016.

Combining these results suggests an important role for the Ebola virus glycoprotein glycan cap and membrane spanning domain in tetherin antagonism.[envelope glycoprotein] (Mus musculus) PubMed

 17017.

This study establishes CodY as a multifaceted factor regulating L. monocytogenes physiology in a highly versatile manner.[CodY] (Mus musculus) PubMed

 17018.

VP39, encoded by SGIV ORF39L,was confined to the cytoplasm, especially at viral assembly sites. [VP39] (Mus musculus) PubMed

 17019.

Our study documents for the first time that erythrocyte surface knob density is related to the PfEMP1 variant expressed. (Mus musculus) PubMed

 17020.

Study identified PNLDC1, an uncharacterized 3'-5' exonuclease, as Trimmer in silkworms. Trimmer is enriched in the mitochondrial fraction and binds to Papi/Tdrkh. Depletion of Trimmer and Papi/Tdrkh additively inhibits trimming, causing accumulation of approximately 35-40-nt pre-piRNAs that are impaired for target cleavage and prone to degradation.[PNLDC1] (Mus musculus) PubMed

 17021.

Results show that Aspergillus niger contains two genes encoding UDP-Galf-transporters. Deletion and localization studies indicate that UgtA and UgtB have redundant functions in the biosynthesis of Galf-containing glycoconjugates. [UgtA] and [UgtB] (Mus musculus) PubMed

 17022.

BfrA: Shortening of BfrA loops appears to be a key mechanism for thermostability. (Mus musculus) PubMed

 17023.

Residues 1-177 of Redbeta contain the determinants for DNA binding and self-oligomerization. [Redbeta] (Mus musculus) PubMed

 17024.

The authors show that SUB1-mediated processing of MSP1 is important for parasite viability, the processing modifies the secondary structure of MSP1 and activates its capacity to bind spectrin.[SUB1] (Mus musculus) PubMed

 17025.

The role of Yvh1 protein in growth, differentiation, and virulence of the rice blast fungus (Mus musculus) PubMed

 17026.

Screening of the mutant collection revealed that Ralstonia pseudosolanacearum Ps29 mutants of RSp0507 and RSc0606 homologs were defective in chemotaxis to l-malate and amino acids, respectively.[RSp0507 and RSc0606 homologs] (Mus musculus) PubMed

 17027.

Deletion of the GRF10 gene, in both C. albicans SN152 and BWP17 strain backgrounds, results in mutants with strongly decreased hyphal growth.[GRF10] (Mus musculus) PubMed

 17028.

Data suggest BtkB exhibits conserved amino acid motifs similar to BtkA; BtkB is activated by autophosphorylation of cytoplasmic catalytic domain; activity is not dependent on autophosphorylation in C-terminal tyrosine. [BtkB, Bruton's tyrosine kinase B] (Mus musculus) PubMed

 17029.

Data suggest FabZ forms hexamer (trimer of dimers); dimeric interface forms substrate-binding tunnel; two natural compounds (mangostin, stictic acid) inhibit FabZ, block active site tunnel. [FabZ, beta-hydroxyacyl-acyl carrier protein dehydratase] (Mus musculus) PubMed

 17030.

Data suggest that substrate/cofactor specificity of DXPS and pyruvate dehydrogenase complex, another thiamin diphosphate-dependent enzyme, extends to methoxy-thiamin diphosphate. [DXPS, 1-deoxy-D-xylulose 5-phosphate synthase] (Mus musculus) PubMed

 17031.

Data suggest FabZ forms hexamer (trimer of dimers); dimeric interface forms substrate-binding tunnel; two natural compounds (mangostin, stictic acid) inhibit FabZ, block active site tunnel. [FabZ, beta-hydroxyacyl-acyl carrier protein dehydratase] (Mus musculus) PubMed

 17032.

Conversely, human T-lymphotropic virus 1 HBZ and human T-lymphotropic virus 2 APH-2 have divergent effects on TGF-beta signaling and IRF-1 transactivation.[HBZ] (Mus musculus) PubMed

 17033.

Conversely, human T-lymphotropic virus 1 HBZ and human T-lymphotropic virus 2 APH-2 have divergent effects on TGF-beta signaling and IRF-1 transactivation.[APH-2] (Mus musculus) PubMed

 17034.

These data combined with cross-linking, molecular dynamics simulations and isothermal calorimetry suggest that Na(+)/H(+) antiporters provide alternating access to the ion-binding site by using elevator-like structural transitions.[NapA] (Mus musculus) PubMed

 17035.

The presented model predicts a substantial elevator-like movement of the dicarboxylate transporter substrate-binding site, with a vertical translation of ~15 A and a rotation of ~43 degrees .[dicarboxylate transporter] (Mus musculus) PubMed

 17036.

This study describes for the first time a conserved P. falciparum ARM repeat protein with a high degree of functional versatility.[PfARO] (Mus musculus) PubMed

 17037.

This study showed an upregulation of selected subpopulations of GNAT3 / alpha-transducin-immunoreactive cells in distinct regions of the pig gastrointestinal tract by short- and long-term high protein diet. [alpha-transducin ] (Mus musculus) PubMed

 17038.

This PA linker binds to PB1 and also forms ionic interactions with the PA C-terminal channel.[PA, PB1] (Mus musculus) PubMed

 17039.

the re-modelling of branched intermediates by RecG plays a fundamental role in directing DNA synthesis and thus maintaining genomic stability.[RecG] (Mus musculus) PubMed

 17040.

Kala4 encodes a bHLH transcription factor.Kala4 regulates anthocyanin biosynthesis pathway.[Kala4] (Mus musculus) PubMed

 17041.

For the first time, the authors also demonstrate that a lysine at position 296 in VP1 is sufficient to confer virulence on an otherwise attenuated murine norovirus strain.[VP1] (Mus musculus) PubMed

 17042.

Substitution of Asp303, Asp304, Asp437 or Glu438 with Ala/Asn/Gln produced a dramatic loss of the beta-N-acetylglucosaminidase activity. [beta-N-acetylglucosaminidase] (Mus musculus) PubMed

 17043.

The results describe the unexpected role of Dhp1/Rat1/Xrn2 in chromatin-based silencing.[Dhp1, Rat1, Xrn2] (Mus musculus) PubMed

 17044.

These data could explain the immunogenicity of PvRAMA antigen in induction of both cell-mediated and antibody-mediated immunity in natural P. vivax infection.[PvRAMA] (Mus musculus) PubMed

 17045.

UGT85K14 was expressed in the representative grape cultivars regardless of species, indicating that furaneol glucoside content is regulated by the biosynthesis of furaneol.[UGT85K14] (Mus musculus) PubMed

 17046.

The results indicate that chondroitin lyases are not essential virulence factors of Flavobacterium columnare but may contribute to the ability of the pathogen to compete and cause disease in natural infections.[cslA, cslB] (Mus musculus) PubMed

 17047.

CagA protein induces epithelial to mesenchymal transition in infected gastric epithelial cells through EPIYA-motif phosphorylation-dependent up-regulation of MMP-3.[CagA] (Mus musculus) PubMed

 17048.

Results found that Llmg_0524 protein had a severe impact on growth and, affected resistance to cumene hydroperoxide and lysozyme suggesting this protein is linked to cell envelope integrity. [Llmg_0524] (Mus musculus) PubMed

 17049.

beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.[ORF2] (Mus musculus) PubMed

 17050.

Two polar residues of this region, serine-183 (S183) and threonine-185 (T185), were identified to be critical for the oligomerization pattern of M1. (Mus musculus) PubMed

 17051.

The UL119-UL118-encoded gp68-mediated endocytosis transports gp68-bound IgG-antigen complexes into endosomes, after which the complex is routed to lysosomes, presumably for degradation.[UL118] (Mus musculus) PubMed

 17052.

E6 proteins of human papillomavirus types 6 and 11 are able to protect keratinocytes from apoptosis via Bak degradation. [E6] (Mus musculus) PubMed

 17053.

A model of the full-length NsrR in the active and inactive state provides insights into protein dimerization and DNA-binding. [NsrR] (Mus musculus) PubMed

 17054.

Furthermore, a direct interaction between AnkA and HDAC1 was detected at the CYBB promoter, and was critical for AnkA-mediated CYBB repression.[AnkA] (Mus musculus) PubMed

 17055.

Seven candidate genes were verified to be required for Pm21 -mediated resistance to wheat powdery mildew. (Mus musculus) PubMed

 17056.

The study presents new crystal structures of DfsB homologues from a variety of bacterial species and a surprising version present in the yeast Saccharomyces cerevisiae. [DfsB] (Mus musculus) PubMed

 17057.

The complex formation mediated by the Clostridium botulinum C3 exoenzyme ARTT-loop is through the intrinsic plasticity of C3 exoenzyme and RhoA. (Mus musculus) PubMed

 17058.

Ligand site prediction determined that amino acid residues GLU-312, TRP-334, ILE-341 and VAL-382 exposed on the surface of the target protein exhibit polar interactions with the substrate. [chitin-binding domain 3 protein] (Mus musculus) PubMed

 17059.

Expression studies reveal that Rhodobacter sphaeroides IscR in its cluster-bound form functions as transcriptional repressor of genes involved in iron metabolism by direct binding to the promoter region of genes preceded by the binding motif.[IscR] (Mus musculus) PubMed

 17060.

BrAOP2.1 showed a slightly different pattern of expression in below-ground tissue at the seedling stage and in the silique at the reproductive stage compared with BrAOP2.2 and BrAOP2.3 genes in B. rapa. [AOP2-2,AOP2-3] (Mus musculus) PubMed

 17061.

Results provide evidence that flagellin may play a role in the in vitro interaction of E. coli BA2103 with cellular fibronectin, and GroEL can be an accessory protein in this process. [FliC] and [GroEL] (Mus musculus) PubMed

 17062.

Disruption of GWT1 with the Agrobacterium tumefaciens-mediated T-DNA random insertional mutagenesis (ATMT) method resulted in constitutive expression of the laccase gene LAC1 and constant melanin formation.[LAC1] (Mus musculus) PubMed

 17063.

All the unique properties, such as thermostability, Cu(2+)-dependent, 3-regiospecificity, and polar organic solvent-tolerance, indicated that AN0512Lip could have potential applications in the food industry (Mus musculus) PubMed

 17064.

As predicted, the fold of a monomer of APRc resembles one-half of the mandatory homodimer of retroviral pepsin-like aspartic proteases, but the quaternary structure of the dimer of APRc differs from that of the canonical retropepsins. [APRc] (Mus musculus) PubMed

 17065.

the crystal structure of RPA3017 in the unphosphorylated form at 1.9 A resolution is presented.[RPA3017] (Mus musculus) PubMed

 17066.

The crystal structure of uracil-DNA N-glycosylase in complex with DNA is reported at a resolution of 1.35 A. [uracil-DNA N-glycosylase] (Mus musculus) PubMed

 17067.

The study presents structural and functional studies of a metallo-beta-lactamase (Tm1162) with a new type of structurally encoded nickel-containing heterodinuclear site. [Tm1162] (Mus musculus) PubMed

 17068.

The crystal structure of the gatekeeper SepL was determined and compared with the structures of SepL homologues from other bacterial pathogens.[SepL] (Mus musculus) PubMed

 17069.

This report characterizes the interaction of NADP+ with nicotinamide mononucleotide adenylyltransferase at the molecular level. [nicotinamide mononucleotide adenylyltransferase] (Mus musculus) PubMed

 17070.

HP119 is a nucleoid-associated protein that plays a large role in aiding bacterial stress resistance. (Review) (Mus musculus) PubMed

 17071.

LEP-2 regulates LIN-28 stability to promote the juvenile-to-adult transition in Caenorhabditis elegans [LEP-2] (Mus musculus) PubMed

 17072.

The structure of PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal, has been reported. [PqsBC] (Mus musculus) PubMed

 17073.

PblB, as an adhesin mediating the galactose-specific adhesion activity of pneumococci, promote pneumococcal clonal success.[PblB] (Mus musculus) PubMed

 17074.

E. coli clinical strain carrying bla NDM-1, bla CTX-M-15, bla CMY-42 and bla SHV-12 was identified.[bla NDM-1, bla CTX-M-15, bla CMY-42 and bla SHV-12 ] (Mus musculus) PubMed

 17075.

VdPR3 is a multifunctional gene involved in growth development, extracellular enzyme activity, and virulence of V. dahliae on cotton. [VdPR3] (Mus musculus) PubMed

 17076.

Data suggest substrate specificity of mRNA (N6-adenosine) methyltransferase involves GAC motif for methylation/demethylation post-transcriptional modification of messenger RNA. [IME4, mRNA (N6-adenosine) methyltransferase] (Mus musculus) PubMed

 17077.

split top, a recessive maternal-effect zebrafish mutant that disrupts embryonic patterning upstream of endogenous BMP signaling, was identified.[Split top] (Mus musculus) PubMed

 17078.

The oxidized ClyA monomer assembles to pore complexes about one order of magnitude faster than the reduced monomer because the unstructured intermediate of oxidized ClyA is less stable and dissolves more rapidly than the reduced intermediate. [ClyA] (Mus musculus) PubMed

 17079.

These findings elucidate that how pH influences Trichoderma reesei cutinase at the atomistic level.[Cutinase] (Mus musculus) PubMed

 17080.

Data suggest SCl2 binds to DDR (DDR1, DDR2) ectodomain w/o stimulating receptor signaling; here, protein engineering was used to construct SCl-like proteins that inhibit collagen-DDR interactions and macrophage migration. [Scl2, collagen-like protein] (Mus musculus) PubMed

 17081.

OsAlaAT1 is localized in cytosol and has aminotransferase enzyme activity. The osalaat1 mutant has less amylose and its amylopectin is structurally altered. OsAlaAT1 is predominantly expressed in developing seeds during active starch synthesis.[AlaAT1] (Mus musculus) PubMed

 17082.

M. truncatula contains two-expressed GSI-like genes, MtGSIa and MtGSIb, encoding polypeptides of 454 and 453 amino acids, respectively. The proteins are not catalytically functional for glutamine synthesis.[ MtGSIa, MtGSIb] (Mus musculus) PubMed

 17083.

Here we perform extensive 4C-seq profiling of the Hox cluster in embryos of amphioxus, an invertebrate chordate (Mus musculus) PubMed

 17084.

Data suggest that activity/stability of trimeric BetP is regulated by lipid-protein interactions; K+ binding weakens lipid-protein interactions of BetP especially with anionic lipid head groups. [BetP, betaine symporter] (Mus musculus) PubMed

 17085.

The putative Ggamma subunit gene MGG1 is required for conidiation, appressorium formation, mating and pathogenicity in Magnaporthe oryzae. [MGG1] (Mus musculus) PubMed

 17086.

PTEX88 likely plays a specific direct or indirect role in mediating parasite sequestration rather than making a universal contribution to the trafficking of all exported proteins. (Mus musculus) PubMed

 17087.

PTEX88 likely plays a specific direct or indirect role in mediating parasite sequestration rather than making a universal contribution to the trafficking of all exported proteins. (Mus musculus) PubMed

 17088.

Study demonstrated that, compared to control by a single regulator, the marRAB regulatory arrangement has the least control cost associated with modulating gene expression in response to environmental stimuli (Mus musculus) PubMed

 17089.

Study, mainly by nuclear magnetic resonance spectroscopy, of the residual secondary structure and long-range interactions in nonstructural protein 5A (NS5A) from hepatitis C virus (Mus musculus) PubMed

 17090.

The authors identified two new human proteins that interact with Ehrlichia chaffeensis EtpE-C: CD147 and heterogeneous nuclear ribonucleoprotein K (hnRNP-K). (Mus musculus) PubMed

 17091.

Data suggest nav1.1 exhibits 2 binding sites for insecticide DDT [1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane]; bulky trichloromethyl group of DDT molecule fits snugly between 4 helices in bent domain interface. [nav1.1, NAV1.1 voltage-gated Na channel] (Mus musculus) PubMed

 17092.

This study shows that syrG and syrF encode important transcriptional regulators of syringomycin biosynthesis genes. (Mus musculus) PubMed

 17093.

The structure of the complex of Rsd and HPr was determined at 2.1 A resolution and revealed that the binding site for HPr on the surface of Rsd partly overlaps with that for sigma-70. [HPr, Rsd] (Mus musculus) PubMed

 17094.

clustering of sensory kinase receptors can be dynamic and context dependent and can be triggered by specific environmental cues [BaeS] (Mus musculus) PubMed

 17095.

The study provides insights into homotropic Cu-binding cooperativity, gas-phase stabilities and conformational ensembles of the D2 -symmetric, homotetrameric copper-sensitive operon repressor (CsoR) as a function of Cu(I) ligation state. [CsoR] (Mus musculus) PubMed

 17096.

ArsP is the first identified efflux system specific for trivalent organoarsenicals [Arsp] (Mus musculus) PubMed

 17097.

BcMctA, a putative monocarboxylate transporter, is required for pathogenicity in Botrytis cinerea. [BcMctA] (Mus musculus) PubMed

 17098.

study demonstrate that polar positioning of the flagellar system, but not of the chemotaxis system, depends on the GTPase FlhF.[FlhF]. (Mus musculus) PubMed

 17099.

AaFPPS displays its activity in the presence of metal cofactors. Mg(2+) ions lead to the production of farnesyl diphosphate, while the presence of Co(2+) ions lead to geranyl diphosphate production. (Mus musculus) PubMed

 17100.

Actin was shown to interact with the Envelope protein of Dengue Virus 2 and 4. [Envelope protein E] (Mus musculus) PubMed

 17101.

Our results suggest a dual phosphorylation-dependent DenA/DEN1 stability control with stabilizing and destabilizing modifications and physical interaction partner proteins which function as control points in the nucleus and the cytoplasm. (Mus musculus) PubMed

 17102.

Actin was shown to interact with the Envelope protein of Dengue Virus 2 and 4. [Envelope protein E] (Mus musculus) PubMed

 17103.

RipAY, a plant pathogen effector protein, exhibits robust gamma-glutamyl cyclotransferase activity when stimulated by the yeast TRX1 and TRX2 thioredoxins. [RipAY] (Mus musculus) PubMed

 17104.

Simulations show that the ligand-induced disorder-to-order transition of the sortase A active-site loop is characterized by merging and compaction of free-energy basins (Mus musculus) PubMed

 17105.

they isolated and characterized a gene, Yob, for the M factor in the malaria mosquito Anopheles gambiae Yob, activated at the beginning of zygotic transcription and expressed throughout a male's life, controls male-specific splicing of the doublesex gene. [Yob] (Mus musculus) PubMed

 17106.

Nuclear resonance vibrational spectroscopy provides data of LytB bound to its natural substrate, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate. [LytB] (Mus musculus) PubMed

 17107.

findings showed that the CDC14 ortholog is important for pathogenesis and morphogenesis in Fusarium graminearum.[CDC14]. (Mus musculus) PubMed

 17108.

results show that nuclei are asymmetrically fed with a transcriptionally active pool of FlbB originating at the tip, reinforcing the hypothesis that the tip-to-nucleus communication in hyphae is a key event controlling developmental transitions in filamentous fungi[FlbB]. (Mus musculus) PubMed

 17109.

These data indicate that TaHIPP1 is an important component in defence signalling pathways and may play a crucial role in the defence response of wheat to biotic and certain abiotic stresses. [TaHIPP1] (Mus musculus) PubMed

 17110.

The EPA2 adhesin encoding gene is responsive to oxidative stress in the opportunistic fungal pathogen Candida glabrata. [EPA2] (Mus musculus) PubMed

 17111.

Data show that ectoine synthase (EctC) forms a dimer with a head-to-tail arrangement in the crystal structure: [EctC] (Mus musculus) PubMed

 17112.

The results altogether show a pivotal role of hmga2 in Xenopus neural crest cell specification. These results strongly suggest, though do not definitely prove, that hmga2 may be required for epithelial-mesenchymal transition also in neural crest cells. (Mus musculus) PubMed

 17113.

Our findings explain the altered PAM specificities of the SpCas9 variants and establish a framework for further rational engineering of CRISPR-Cas9. (Mus musculus) PubMed

 17114.

Guided by the structural data, we engineered a SpCas9 variant that specifically recognizes NAAG PAMs. Taken together, these studies inform further development of Cas9-based genome editing tools (Mus musculus) PubMed

 17115.

Increased expression of the ornithine decarboxylase gene demonstrates its involvement in acid stress response in Lactobacillus delbrueckii UFV H2b20.[ornithine decarboxylase] (Mus musculus) PubMed

 17116.

FeoE, a member of the cation diffusion facilitator (CDF) protein family, functions to export excess Fe(2+) from the MR-1 cytoplasm. Mutants lacking feoE exhibit an increased sensitivity to Fe(2+). The export function of FeoE is specific for Fe(2+).[FeoE] (Mus musculus) PubMed

 17117.

As the antimalarial drug atovaquone acts as a competitive inhibitor of CoQ, we assessed whether over-expression of PfCoq10 altered the atovaquone sensitivity in parasites and in yeast mitochondria, but found no alteration of its activity. (Mus musculus) PubMed

 17118.

data suggest a pivotal role for APF1 in mediating the interaction of LG2055 with human intestinal cells and in inhibiting C. jejuni colonization of the gastrointestinal tract [APF1] (Mus musculus) PubMed

 17119.

Analysis showed that TRI6 negatively regulates genes of the branched-chain amino acid (BCAA) metabolic pathway.[TRI6]. (Mus musculus) PubMed

 17120.

crystal structure of D-alanine-D-alanine ligase (DDL) at a resolution of 2.2 A; the asymmetric unit contained six protomers of AbDDL DDL] (Mus musculus) PubMed

 17121.

The type IV pilus assembly ATPase PilB of Myxococcus xanthus interacts with the inner membrane platform protein PilC and the nucleotide-binding protein PilM. [PilB], [PilC], [PilM] (Mus musculus) PubMed

 17122.

Data suggest that Skp1 (E3 ubiquitin ligase adaptor) hydroxyproline (Pro154) is glycosylated with pentasaccharide via glycosyltransferases Gnt1 and PgtA; disruption of Gnt1 or PgtA results in decreased parasite growth. [Skp1, Gnt1, and PgtA] (Mus musculus) PubMed

 17123.

Data suggest that Phe231 and Trp233 in C-terminal region of DnaC contribute to binding site for ssDNA, thermostability in binding to DnaB helicase, and loading of complex at DnaA box. [DnaA, DnaB, and DnaC] (Mus musculus) PubMed

 17124.

Candida albicans Bar1 was purified and shown to exhibit preferential cleavage of native alpha pheromone over pheromones from related fungal species.[Bar1] (Mus musculus) PubMed

 17125.

A glutamate/aspartate switch controls product specificity in a protein arginine methyltransferase. (Mus musculus) PubMed

 17126.

all imipenem-resistant isolates showed no significant expression of OprD; results show the low permeability of drugs due to mutational inactivation of OprD is primarily responsible for carbapenem resistance in bloodstream isolates of P. aeruginosa from Korean hospitals [OprD] (Mus musculus) PubMed

 17127.

This study identified a novel exopeptidase, designated acylpeptidyl oligopeptidase (AOP), composed of 759 amino acid residues with active Ser(615). [acylpeptidyl oligopeptidase] (Mus musculus) PubMed

 17128.

OsCOMT was localized in the cytoplasm. In vitro ASMT activity was significantly inhibited by caffeic acid or quercetin in a dose-dependent manner. In vivo production of melatonin was significantly inhibited by quercetin in detached rice leaves.[ASMT] (Mus musculus) PubMed

 17129.

Escherichia coli YihQ protein have been identified as the first dedicated sulfoquinovosidase and the gateway enzyme to sulfoglycolytic pathways. (Mus musculus) PubMed

 17130.

Data suggest that LPMO10A chitinase (a multi-modular chitinase) contains a small (15.5 kDa; 142 AA residues) lytic polysaccharide monooxygenase domain (GH18) that exhibits substrate specificity toward alpha- and beta-chitin. [LPMO10A; GH18 chitinase] (Mus musculus) PubMed

 17131.

The authors show that Human papillomavirus type 16 L2 is cleaved during virion morphogenesis in differentiated tissue and that tissue-derived native virus initiates infection independent of cellular furin. (Mus musculus) PubMed

 17132.

the defensin mNP-1 can promote regeneration after a peripheral nerve cut. [defensin NP-1] (Mus musculus) PubMed

 17133.

This study aimed to investigate the presence of Cdr1as/miR-7a pathway in cardiomyocytes.[Cdr1as] (Mus musculus) PubMed

 17134.

MML-1/MXL-2 and HLH-30 transcriptomes show both shared and preferential outputs including MDL-1/MAD-like HLH factor required for longevity.[MML-1, MXL-2, TOR] (Mus musculus) PubMed

 17135.

IL-32gamma transgenic mice showed higher rates of osteoblast differentiation than WT mice[il-32] (Mus musculus) PubMed

 17136.

SecYEG dimers are functional units of the translocon. [SecYEG] (Mus musculus) PubMed

 17137.

the newly determined crystal structure of influenza B virus HA2 in the postfusion state. [HA2] (Mus musculus) PubMed

 17138.

The data indicate that lymphostatin has UDP-sugar binding potential that is critical for activity, and is a major leap toward identifying the nature and consequences of modifications of host cell factors. [lymphostatin] (Mus musculus) PubMed

 17139.

The role of MlaA lipoprotein in the cell wall phospholipid metabolism [MlaA] (Mus musculus) PubMed

 17140.

Rsembling elongation factor G, EF-Tu appears to be sensitive to ROS via oxidation of a cysteine residue, and its inactivation might be reversed in a redox-dependent manner. [Elongation Factor EF-Tu] (Mus musculus) PubMed

 17141.

Data suggest alpha/beta-hydrolase fold-structural homology between two bacterial L-homoserine O-acetyl transferases: Hle from Corynebacterium glutamicum and MekB from Pseudomonas veronii. [Hle, L-homoserine O-acetyl transferase] (Mus musculus) PubMed

 17142.

Data suggest Maf1 has role in regulation of glucose metabolism/glycolysis, fermentation, lipid homeostasis; Maf1 deletion up-regulates pyruvate kinase activity/glucose fermentation. [Maf1, RNA polymerase III-inhibiting protein AND CDC19, pyruvate kinase] (Mus musculus) PubMed

 17143.

Data suggest pheromones are capable of activating SLT2 and the cell wall integrity MAP kinase signaling pathway through direct interactions of MAP kinase kinases STE1 with MKK1 and MKK2; these processes involve NST1. (STE11, MKK1, and MKK2) (Mus musculus) PubMed

 17144.

CTCF binds to the provirus at a sharp border in epigenetic modifications in the pX region of the HTLV-1 provirus in T cells naturally infected with HTLV-1. pX protein. (Mus musculus) PubMed

 17145.

Cdc24 is required for the establishment of hyphal polarity and localizes to hyphal tips.[cdc42] (Mus musculus) PubMed

 17146.

The discovery that Lia3 binds G-quadruplex DNA and controls the accuracy of DNA elimination at loci with specific G-tracts uncovers an unrecognized potential of quadruplex structures to regulate chromosome organization. (Mus musculus) PubMed

 17147.

We have further identified an HDR1-interacting kinase, OsK4, another suppressor of rice flowering under long day condition (Mus musculus) PubMed

 17148.

study uncovered an important role for YopJ in inhibiting caspase-1 in activated macrophages and in promoting Yersinia virulence[YopJ] (Mus musculus) PubMed

 17149.

data provide the most complete picture to date of how the earliest SIR1-containing SIR silencing complex functioned and the evolutionary trajectories it may have followed (SIR1) (Mus musculus) PubMed

 17150.

SodB may not be important in scavenging superoxide radicals induced by methyl viologen [SodB] (Mus musculus) PubMed

 17151.

show that ToxR shares more than a third of its regulon with the histone-like nucleoid structuring protein H-NS[ToxR] (Mus musculus) PubMed

 17152.

This study has identified that cysteine protease 5 coupling with goblet cell alphavbeta3 receptors can initiate a signal cascade...to drive mucin secretion from goblet cells critical in disease pathogenesis. (Mus musculus) PubMed

 17153.

molecular cloning and characterization of ilvB GST-recombinant fusion protein [ilvB] (Mus musculus) PubMed

 17154.

The DNA-binding properties of Mgm101, together with its DNA recombination properties, suggest that it can play a number of possible roles in the replication of the mitochondrial genome and the maintenance of its telomeres. [Mgm101] (Mus musculus) PubMed

 17155.

The present results demonstrated the glucose and xylose co-utilization efficiency and the product yield and productivity can be significantly improved if a suitable PTS(Glc) deletion mutant was selected.[PTS(Glc)] (Mus musculus) PubMed

 17156.

ZHOUPI, an endosperm-specific basic helix-loop-helix transcription factor involved in maize seed development.[ZHOUPI] (Mus musculus) PubMed

 17157.

CYP71E1 catalyzes the isomerization of (E)-p-hydroxyphenylacetaldoxime into (Z)-p-hydroxyphenylacetaldoxime [CYP71e1] (Mus musculus) PubMed

 17158.

This structural study revealed the recognition and inhibition mechanism of RnlA from Escherichia coli by bacteriophage T4 antitoxin Dmd. [RnlA] (Mus musculus) PubMed

 17159.

TMEM-218 requires CEP-290 and other Meckel syndrome module components for ciliary transition zone localization, and functions together with the nephronophthisis module to facilitate ciliogenesis [Tmem218, Cep290] (Mus musculus) PubMed

 17160.

Under optimal watering conditions, transgenic TaNF-YB4 wheat plants produced significantly more spikes but other yield components did not change, resulting in a 20-30% increased grain yield compared with untransformed control plants.[NF-YB4] (Mus musculus) PubMed

 17161.

The kinase TaAGC1 positively contributes to wheat immunity to Rhizoctonia cerealis through regulating expression of ROS-related and defence-associated genes.[AGC1] (Mus musculus) PubMed

 17162.

The MdSHN3 transcription factor gene displayed extremely low expression in lines with improper cuticle formation, suggesting it to be a fundamental regulator of cuticle biosynthesis in apple fruit.[SHN3] (Mus musculus) PubMed

 17163.

The HPT1 promoter region contains multiple motifs related to regulation by jasmonate, abscisic acid, low temperature and light, and an ATCTA motif presents in genes involved in tocopherol biosynthesis and some photosynthesis-related genes.[HPT1] (Mus musculus) PubMed

 17164.

Immunohistochemical data suggest cetacean placental trophoblasts exhibit P450scc (cholesterol side-chain cleavage enzyme), P450arom (aromatase), and UF (uteroferrin) in during pregnancy. [P450scc, P450arom, and UF] (Mus musculus) PubMed

 17165.

Membrane-bound MinD and MinE complex acts as a toggle switch that drives Min oscillation coupled to cytoplasmic depletion of MinD.[MinE] [MinD] (Mus musculus) PubMed

 17166.

This study defined a subset of Rab GTPases targeted by SidM and LidA during infection, comprising of Rab1A, 1B, 6, and 10; in addition, LidA targets Rab14 and 18. [SidM, LidA] (Mus musculus) PubMed

 17167.

The gbpA mutant had attenuated virulence and ability of intestinal colonization in a mouse model, indicating that gbpA is a mucin-binding protein and essential for pathogenesis of V. vulnificus. [gbpA] (Mus musculus) PubMed

 17168.

TSP3 is a vacuolar membrane protein and is dispensable for growth and development. [TSP3] (Mus musculus) PubMed

 17169.

Overexpression of OspPLAIIIalpha resulted in a dwarf phenotype with decreased length of rice stems, roots, leaves, seeds, panicles, and seeds, whereas OspPLAIIIalpha-knockout plants had longer panicles and seeds.[pPLAIIIalpha] (Mus musculus) PubMed

 17170.

monoubiquitylation of Nup60 is stimulated upon genotoxic stress and regulates the DNA-damage response and telomere repair; data reveal an original mechanism contributing to the plasticity of the nuclear pore complex (Nup60) (Mus musculus) PubMed

 17171.

Copaifera langsdorffii leaf extracts alter the pattern of expression of the SHORT-ROOT and HD-ZIP III transcription factor gene family and cause morpho-physiological alterations in Sorghum bicolor roots.[SHORT-ROOT, HD-ZIP III] (Mus musculus) PubMed

 17172.

high quality model of HA1 amino acid structure consistent with available sequence/function information [hemagglutinin HA1, influenza B virus] (Mus musculus) PubMed

 17173.

Cytoplasmic tail domain of glycoprotein B is essential for HHV-6 propagation and important for intracellular transportation. [gB] (Mus musculus) PubMed

 17174.

The role of the CydD and CydC transporters in redox homoeostasis during nitrosative stress, and the ability of periplasmic low molecular weight thiols to restore haem incorporation into a cytochrome complex are reported.[CydD; CydC] (Mus musculus) PubMed

 17175.

These results suggest that NdhM localizes in the hydrophilic subcomplex of NDH-1 complexes as a core subunit and is essential for the function of NDH-1MS and NDH-1MS' involved in CO2 uptake. [NdhM] (Mus musculus) PubMed

 17176.

SNAC3 was ubiquitously expressed and its transcript level was induced by drought, high temperature, salinity stress, and abscisic acid treatment. Overexpression resulted in enhanced tolerance to high temperature, drought, and oxidative stress.[SNAC3] (Mus musculus) PubMed

 17177.

This evidence of a UmuDAb repressor mechanism was contrasted with the failure of umuDAb to complement an Escherichia coli umuD mutant for UmuD error-prone DNA replication activity (Mus musculus) PubMed

 17178.

These findings further strengthened the role of flagella in the adherence of a EPEC to human enterocytes and disclosed the relevant structural and functional involvement of FliD in the adhesion process.[FliD] (Mus musculus) PubMed

 17179.

Mit1 activates genes involved in the MUT pathway but does not participate in peroxisome proliferation. [Mit1] (Mus musculus) PubMed

 17180.

the present study characterized the aminoacetone oxidase (SoAAO) structure-function relationship.[SoAAO] (Mus musculus) PubMed

 17181.

identified and characterized a novel epoxide hydrolases (EH) (TpEH1) from Tsukamurella paurometabola by analyzing the conserved catalytic residues of EH.[epoxide hydrolases]. (Mus musculus) PubMed

 17182.

our results show that APIP10 is a novel E3 ligase that functionally connects the fungal effector AvrPiz-t to its leucine-rich repeat receptor Piz-t in rice (Mus musculus) PubMed

 17183.

These results demonstrate an autoregulatory mechanism that fine-tunes the expression of the Rpl22 protein and by extension Rpl22p paralog composition according to the cellular demands for ribosome biogenesis. [Rpl22] (Mus musculus) PubMed

 17184.

It appears as if H-NS mutant cells adopt a "slow-growth" type of chromosome organization under nutrient-rich conditions, which leads to a decreased cellular DNA content.[H-NS] (Mus musculus) PubMed

 17185.

P. aeruginosa PAO1 acquires zinc via an ATP-binding cassette (ABC) permease in which ZnuA is the high affinity, zinc-specific binding protein.[ZnuA] (Mus musculus) PubMed

 17186.

Mutational analysis of varicella-zoster virus immediate early protein (IE62) subdomains and their importance in viral replication have been presented. [IE62] (Mus musculus) PubMed

 17187.

ThFgap1 mediated response to oxidative stress and response to diamide.[Fgap1] (Mus musculus) PubMed

 17188.

Two-component regulatory system proteins encoded by Npun_F1277 and Npun_F1278 are upregulated by UV light. [Npun_F1277 and Npun_F1278 ] (Mus musculus) PubMed

 17189.

The M1 missense mutations in the putative cholesterol binding site of alpha-helix 2, alpha-helix 3 and alpha-helix 8 resulted in viruses with unusual filamentous morphology.[M1] (Mus musculus) PubMed

 17190.

C. crescentus aldose-aldose oxidoreductase (AAOR) is a novel type of oxidoreductase able to convert the single aldose substrate D-xylose to both its oxidized and reduced product.[aldose-aldose oxidoreductase]. (Mus musculus) PubMed

 17191.

The physiological studies have shown that a constructed deletion of dasR in Saccharopolyspora erythraea resulted in antibiotic, pigment, and aerial hyphae production deficit in a nutrient-rich condition.[DasR] (Mus musculus) PubMed

 17192.

IrrB appears to be directly responsible for iron metabolism and homeostasis and indirectly involved in magnetosome formation. We propose two IrrB-regulated networks (in high- and low-iron conditions) in Magnetospirillum gryphiswaldense MSR-1 cells.[IrrB] (Mus musculus) PubMed

 17193.

These results strongly suggest a crucial role of Kin28 kinase-dependent gene looping in the termination of transcription in budding yeast.[Kin28] (Mus musculus) PubMed

 17194.

Knock-down of TbBRF1 by RNA interference showed that this protein is essential for the viability of procyclic forms of T. brucei, since ablation of TbBRF1 led to growth arrest of the parasites (BRF1). (Mus musculus) PubMed

 17195.

The crystal structure, in conjunction with physicochemical analysis in solution, reveals a symmetrical homo-trimeric arrangement for minor pilin CofB of Escherichia coli.[CofB] (Mus musculus) PubMed

 17196.

The functional and structural characterization of a new Formate Dehydrogenase, GraFDH, identified by mining the genome of the extremophile prokaryote Granulicella mallensis MP5ACTX8 is reported. [Formate dehydrogenase]. (Mus musculus) PubMed

 17197.

These results indicate, for the first time, that binding to Anx2 is beneficial for infectious bursal disease virus infection.[Anx2] (Mus musculus) PubMed

 17198.

Circadian expression of osa-miR1848 regulated the diurnal abundance of OsCYP51G3 transcript in developing organs, and the response of OsCYP51G3 to salt stress. [CYP51G3; miR1848] (Mus musculus) PubMed

 17199.

study found trxB2 gene has an essential role in L. lactis when the bacterium grows in the presence of oxygen, whereas growth is unaffected in the absence of oxygen [trxB2] (Mus musculus) PubMed

 17200.

The Autophagy-Related Protein (ATG8) is essential for maintaining apicoplast homeostasis and thus for survival of the tachyzoite stage.[ATG8]. (Mus musculus) PubMed

 17201.

Nonetheless, nucleotide sequence analysis revealed low genetic diversity of the DI domain of AMA-1, and it was under purifying (negative) selection[AMA-1] (Mus musculus) PubMed

 17202.

G72-transgenic mice presenting some psychiatric symptoms, along with the pLG72 level being significantly increased in the serum of patients with schizophrenia, have led us to propose that the ROS enhancement in mental diseases (Mus musculus) PubMed

 17203.

WetA and VosA are indispensable for asexual development and contribute differentially to conidial quality and hence the biological control potential of Beauveria bassiana against insect pests.[WetA, VosA] (Mus musculus) PubMed

 17204.

Here, the authors demonstrated that core capsid protein P3 and nonstructural protein Pns11 were recruited in the viroplasm by direct interaction with Pns12, whereas nonstructural protein Pns6 was recruited through interaction with Pns11. [Pns12] (Mus musculus) PubMed

 17205.

Analyzed the monomer sequence specificity of Polyhydroxyalkanoate depolymerase (PhaZVs) for hydrolyzing P(LA-co-3HB) in comparison with a P(3HB) depolymerase from Alcaligenes faecalis T1 (PhaZAf. [Polyhydroxyalkanoate depolymerase]. (Mus musculus) PubMed

 17206.

Binding of Sp1 to the 5' splice site region had an inhibitory effect on L4-22K-activated major late promoter transcription.[L4-22K] (Mus musculus) PubMed

 17207.

(gene col6a4b) col6a4b long chain in zebrafish that are essential for muscle development. Knockdown leads to muscle defects, reminiscent of those observed in col6a2 deficiency, although some specific features emerged. (Mus musculus) PubMed

 17208.

Bacterial protein-E and host vitronectin play a role in the attachment to bronchial epithelial cells and is also involved in the subsequent intracellular invasion of nontypeable Haemophilus influenzae.[protein-E] (Mus musculus) PubMed

 17209.

AefR binds to its own operator site as well as to the palindromic sequence between positions -28 and -2 corresponding to the transcription start site of aefR, as determined by dye primer sequencing. These results suggest that P. syringae AefR modulates quorum sensing and efflux as well as its own expression. [AefR] (Mus musculus) PubMed

 17210.

These findings suggest that TdERF1 might be involved in responses to salt and water stress providing a potential genetic marker discriminating between tolerant and sensitive wheat varieties. (Mus musculus) PubMed

 17211.

Null adcA and lmb mutants were analysed for their capability to grow in zinc-depleted conditions and were found to be more susceptible to zinc starvation, a phenotype that could be rescued by the addition of Zn2+ ions to the growth medium. [adcA, lmb] (Mus musculus) PubMed

 17212.

Mechanism of DNA loading by the DNA repair helicase XPD has been described. [XPD] (Mus musculus) PubMed

 17213.

Presented is the mutational and functional analysis of N-linked glycosylation of envelope fusion protein F of Helicoverpa armigera nucleopolyhedrovirus. [f protein] (Mus musculus) PubMed

 17214.

Data suggest that two Cslf6 orthologs from different cereal species (Hordeum vulgare and Sorghum bicolor) catalyze synthesis of (1,3;1,4)-beta-glucans (dietary fibers) with very different fine structures. [Cslf6, cellulose synthase-like CslF6] (Mus musculus) PubMed

 17215.

The structures of the native enzyme and the FMN complex of the overexpressed form of the oxygenating component of the type II Baeyer-Villiger 3,6-diketocamphane monooxygenase have been determined to 1.9 A resolution. [3,6-diketocamphane monooxygenase] (Mus musculus) PubMed

 17216.

The DENV-1 to DENV-4 NS5 forms are elongated and flexible in solution, with DENV-4 NS5 being more compact relative to NS5 from DENV-1, DENV-2 and DENV-3. [NS5] (Mus musculus) PubMed

 17217.

The structure determination of NorM transporter is described, which had been hampered by low resolution ( approximately 4 A), data anisotropy and pseudo-merohedral twinning. [NorM] (Mus musculus) PubMed

 17218.

Reported here is the first structure of an superoxide reductase from a eukaryotic organism, the protozoan parasite Giardia intestinalis, which was solved at 2.0 A resolution. [superoxide reductase] (Mus musculus) PubMed

 17219.

The DENV-1 to DENV-4 NS5 forms are elongated and flexible in solution, with DENV-4 NS5 being more compact relative to NS5 from DENV-1, DENV-2 and DENV-3. [NS5] (Mus musculus) PubMed

 17220.

The DENV-1 to DENV-4 NS5 forms are elongated and flexible in solution, with DENV-4 NS5 being more compact relative to NS5 from DENV-1, DENV-2 and DENV-3. [NS5] (Mus musculus) PubMed

 17221.

The DENV-1 to DENV-4 NS5 forms are elongated and flexible in solution, with DENV-4 NS5 being more compact relative to NS5 from DENV-1, DENV-2 and DENV-3. [NS5] (Mus musculus) PubMed

 17222.

Here, the high-resolution structural characterization of the oxygen-sensing globin domain of YddV, the middle domain and the catalytic GGDEF domain in apo and substrate-bound forms is described. [YddV] (Mus musculus) PubMed

 17223.

Transcriptomic analysis revealed a wide perturbation of gene expression with induction of stress-regulated genes upon phosphate starvation in wild-type but not Deltamyo1 cells. (Mus musculus) PubMed

 17224.

fission yeast kinesin-8 controls chromosome congression by an alternative mechanism. (Mus musculus) PubMed

 17225.

Data suggest that GH5/Man5_8, an endo-1,4-beta-mannanase, exhibits binding site and substrate specificity for soluble dietary fibers, mannan and galactomannan. [GH5, Man5_8, endo-1,4-beta-mannanase] (Mus musculus) PubMed

 17226.

Pup is conjugated to proteins by Dop and PafA . Tight Pup binding and the limited degree of Dop interaction with high-molecular-weight pupylated proteins results in preferred Pup deamidation over protein depupylation by this enzyme. (Pup. Dop. PafA). (Mus musculus) PubMed

 17227.

Escherichia coli NleC cleaved both p65 and p50 within the Rel homology domain (RHD) and two motifs, E22IIE25 and P177VLS180 , within the RHD of p65 were important for recognition and binding by NleC.[NleC] (Mus musculus) PubMed

 17228.

Flow cytometry and quantitative microscopic image analysis revealed that Rab5 and Rab7A are required for the biogenesis of amoebic giant endocytic vacuoles (GEVs) and regulate the early phase of intracellular trafficking of transferrin.[Rab5] (Mus musculus) PubMed

 17229.

Data suggest that SasG (S. aureus) and Aap (S. epidermidis) are highly repetitive, cell surface proteins involved in biofilm accumulation; both proteins exhibit intrinsic disorder and bind fibronectin. [REVIEW] [SasG, Surface protein G] (Mus musculus) PubMed

 17230.

Data suggest that Aap (S. epidermidis) and SasG (S. aureus) are highly repetitive, cell surface proteins involved in biofilm accumulation; both proteins exhibit intrinsic disorder and bind fibronectin. [REVIEW] [Aap, accumulation associated protein] (Mus musculus) PubMed

 17231.

Data suggest that the centriolar protein SAS-6 instruct cartwheel symmetry, leading to a model that the cartwheel and the microtubule wall assemble in an interdependent manner to establish the native architecture of centrioles: [SAS-6] (Mus musculus) PubMed

 17232.

Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain has been presented. [Ns2] (Mus musculus) PubMed

 17233.

These data are consistent with the model that PBLP has an important role in parasite invasive-stage morphogenesis throughout the parasite life cycle.[PBLP] (Mus musculus) PubMed

 17234.

These data reveal a previously unknown functional heterogeneity in the interaction between Plasmodium falciparum PfEMP1 CIDRalpha1domain binding to EPCR and have major implications for understanding the distinct clinical pathologies of cerebral malaria. (Mus musculus) PubMed

 17235.

Overall, these findings reveal a much greater complexity of how Plasmodium falciparum PfEMP1 CIDRalpha1 domain-expressing parasites may modulate malaria pathogenesis through EPCR adhesion. (Mus musculus) PubMed

 17236.

proper termination of DNA damage checkpoint signaling following the bypass of replication blocks imposed by alkylated DNA adducts requires the concerted and highly complementary actions of Slx4 and the PP4 phosphatase (PP4 Phosphatase) (Mus musculus) PubMed

 17237.

The OCP N-terminal domain burrows into the phycobilisome, leaving the OCP C-terminal domain outside. N-terminal domain penetration brings the OCP carotenoid to within 5-10 A of core chromophores. Core structure change may cause energy dissipation. (Mus musculus) PubMed

 17238.

CRK9 ablation prevented trypanosomes from establishing lethal infections in mice. (Mus musculus) PubMed

 17239.

The results suggest that phosphorylation of Ser-80 of VP1 and Ser-254 of VP2 is crucial for human BK virus propagation. (Mus musculus) PubMed

 17240.

The dynamic behavior of the Simian Virus 40 hexameric helicase bound to DNA was investigated by performing molecular dynamics simulations employing a coarse-grained model.[E1 helicase] (Mus musculus) PubMed

 17241.

these results support a central role of VP4 acting as a viroporin in the perforation of cellular membranes to trigger SV40 viral release.[VP4] (Mus musculus) PubMed

 17242.

viroporin activity of the minor structural proteins VP2 and VP3 is required for SV40 propagation [viroporin] (Mus musculus) PubMed

 17243.

These findings establish the newly identified NpunR4017 as a zinc efflux transporter and a key transporter for maintaining zinc homeostasis in Nostoc punctiforme.[NpunR4017] (Mus musculus) PubMed

 17244.

Data shoe that the N-acetylmuramoyl-l-alanine amidase AmiC2 (Npun_F1846; EC 3.5.1.28) generates arrays of nanopores in the septal peptidoglycan: [AmiC2] (Mus musculus) PubMed

 17245.

Expressed 1918 pandemic influenza viral neuraminidase has inactive and active forms. The inactive form contains high level of core-6 fucose, while the active form lacks such modification. [neuraminidase] (Mus musculus) PubMed

 17246.

transcript and proteomic analysis of Acaryochloris marina reveal that both 8-Vinyl Reductases (8VRs), bciA and bciB, are expressed and their encoded proteins are present in the cell; hypothesize that two 8VRs are employed to ensure that only Chlorophylls carrying 8E groups are synthesized in these strains [bciA, bciB] (Mus musculus) PubMed

 17247.

both N-and C-terminal amino acid residues of CssA and CssB play a critical role in intermolecular interactions between them and assembly proteins; results indicate involvement of the side chains of identified amino acids in CS6 assembly; study adds a step toward understanding interactions between structural subunits of CS6 and assembly proteins during CS6 biogenesis [CssB] (Mus musculus) PubMed

 17248.

Luteolin may inhibit tumor angiogenesis and tumor cell proliferation by down-regulation of LFA- 3 and PCNA and up-regulation of ICAM-1 in tumor tissue of tumor-bearing mice, thereby achieving its anti-tumor effect. (Mus musculus) PubMed

 17249.

we examined the percentage of contacts with positive indices for Mycobacterium leprae DNA and phenol-glycolipid-1 antigen (PGL-1) of oral and nasal secretions of 808 leprosy contacts (Mus musculus) PubMed

 17250.

Production of blaOXA-23 enzyme and pilus molecular chaperone to guide synthesis of CsuC protein may be involved in the resistance of A. baumannii to carbapenems. LC-MS/ MS provides a quick and easy method for carbapenemase detection. (Mus musculus) PubMed

 17251.

The results here suggest there are significant differences among the three BrBAK1 kinases for their effects on plant architecture (Mus musculus) PubMed

 17252.

Novel type XII staphylococcal cassette chromosome mec harboring a new cassette chromosome recombinase, CcrC2, has been described. [CcrC2] (Mus musculus) PubMed

 17253.

Data (including data from quantum mechanical/molecular mechanical models) suggest thiamine diphosphate activation of TKL1 proceeds via intermolecular process (not intramolecular process as previously reported in the literature). [TKL1, transketolase] (Mus musculus) PubMed

 17254.

Cell wall recycling-linked coregulation of AmpC and PenB beta-lactamases occurs through ampD mutations in Burkholderia cenocepacia. [ampC]; [PenB]; [ampD] (Mus musculus) PubMed

 17255.

Mutations of PsbJ on and near the QC site of photosystem II may modulate the short-term light response in cyanobacteria.[PsbJ protein, Synechocystis sp.PCC6803] (Mus musculus) PubMed

 17256.

During sporulation in Bacillus subtilis, the phosphatase SpoIIE is compartmentalized in the small cell by transfer from the polar septum to the adjacent cell pole where SpoIIE is protected from proteolysis and activated.[SpoIIE] (Mus musculus) PubMed

 17257.

findings suggest that the Mieap-regulated mitochondrial quality control plays a critical role in preventing mouse intestinal tumorigenesis [Mieap] (Mus musculus) PubMed

 17258.

The role of residue 67 in IMP-1 type metallo-beta-lactamase evolution has been elucidated. [Imp-1] (Mus musculus) PubMed

 17259.

This paper reports the cloning and sequencing of a lectin molecule, CLEC4T1, in rainbow trout that is a homologue of the CLEC4 family. (Mus musculus) PubMed

 17260.

study investigated the topology and structure-function relationships of the Bacillus megaterium QM B1551 GerUD protein, which is associated with the GerU Germinant receptors (GRs) [GerUD]. (Mus musculus) PubMed

 17261.

Avermectin biosynthesis was significantly increased in DeltaphoP deletion mutants.[phoP] (Mus musculus) PubMed

 17262.

This study determined the relation of the RNA helicase, ATP binding, and nuclease activities of RNase R. [RNase R] (Mus musculus) PubMed

 17263.

These results provide strong evidence for the existence of NusA-binding sites in different operons that are also the targets of Rho-dependent terminations. [NusA, Rho factor] (Mus musculus) PubMed

 17264.

TcdB proteins target Rac, Cdc42, Rap, and R-Ras and glucosylates RhoA.[TcdB] (Mus musculus) PubMed

 17265.

TosR as a dual regulator of the tos operon, which could control the tos operon in association with H-NS and Lrp. [H-NS, Lrp, TosR] (Mus musculus) PubMed

 17266.

Data suggest MNYDI peptide inhibitor interacts with active sites of CysK/CysM through hydrogen bonding involving C-terminal carboxylate and hydrophobic interactions involving Ile5/Tyr3 of MNYDI. [CysK and CysM, O-acetylserine sulfhydrylases K and M] (Mus musculus) PubMed

 17267.

Diminished expression of a small number of mRNAs and 22 small RNAs in the cshA mutant.[CshA] (Mus musculus) PubMed

 17268.

Date show that fourteen single nucleotide polymorphisms (SNPs) markers in the target region were genotyped and were confirmed to associate with clubroot resistance gene Rcr1:[Rcr1] (Mus musculus) PubMed

 17269.

This data suggested that Tim-3/Gal-9 may play a role in Plasmodium berghei ANKA-induced acute lung injury [Tim-3, Gal-9]. (Mus musculus) PubMed

 17270.

Data suggest that substrate specificity exhibited by Cas2 as endonuclease includes both DNA and RNA; its activity is more inclined toward RNA than DNA when given a chance to act on either substrate. [Cas2, CRISPR-associated protein Cas2] (Mus musculus) PubMed

 17271.

findings show that the RipA endopeptidase, which has been considered essential for cell division in certain mycobacteria, is not essential but that at least it or a similar protein, RipB, must be expressed by the bacteria for viability [RipA, RipB] (Mus musculus) PubMed

 17272.

Data (including data from engineered fusion proteins) suggest Glu162 in oxdc plays functional role in reaction specificity, orienting active-site loop in conformation that promots decarboxylation rather than oxidation. [oxdc, oxalate decarboxylase] (Mus musculus) PubMed

 17273.

Data suggest Tte1186 (SCIFF radical SAM maturase) catalyzes formation of thioether cross-links in proteins (converting 2 CYS to cysteine); one substrate of Tte1186 is SCIFF peptide (six cysteines in forty-five peptide). [Tte1186] (Mus musculus) PubMed

 17274.

IgdE, a novel cysteine protease cleaves porcine IgG with high specificity in the hinge region. [cysteine protease] (Mus musculus) PubMed

 17275.

The X-ray crystal structure of the full-length spr1814 in complex with a phosphate analogue beryllium fluoride (BeF3(-)) was determined at 2.0 A. [spr1814] (Mus musculus) PubMed

 17276.

Presented is a high resolution crystal structures of periplasmic glucose-binding protein from Pseudomonas putida CSV86 in unliganded form (2.5 A) and complexed with glucose (1.25 A) and galactose (1.8 A). [glucose-binding protein] (Mus musculus) PubMed

 17277.

PfXPD displays the characteristic ssDNA-dependent ATPase and 5'-3' DNA helicase activities. PfXPD colocalizes with Pfp44 in the nucleus and where they interact with each other. (Mus musculus) PubMed

 17278.

These studies imply that the VAMP714-mediated trafficking pathway plays an important role in rice blast resistance as well as in the vegetative growth of rice.[VAMP714] (Mus musculus) PubMed

 17279.

A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor. (Mus musculus) PubMed

 17280.

CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent DNA repair resection. [CRL4(Wdr70)] (Mus musculus) PubMed

 17281.

Carpel number variation appears to be controlled by a single gene, CsCLV3, which is a homolog of the Arabidopsis gene CLAVATA3. [Cn] (Mus musculus) PubMed

 17282.

In this study an Ascorbate Peroxidase 6 gene, Apx6, was cloned from T. salsuginea and its responses to abiotic stresses in transgenic Arabidopsis were studied. [Apx6] (Mus musculus) PubMed

 17283.

Rifampin phosphotransferase is an unusual antibiotic resistance kinase. [Rifampin phosphotransferase] (Mus musculus) PubMed

 17284.

Echinophora platyloba extract is effective in reducing CDR1 and CDR2 expression which in turn plays an important role in fluconazole resistance in Candida albicans. (Mus musculus) PubMed

 17285.

TdSHN1 isolated from durum wheat encodes an abiotic stress-inducible, transcription factor which confers abiotic stress tolerance in yeast. (Mus musculus) PubMed

 17286.

The first report is presented on the IncI1/ST898 conjugative plasmid carrying rmtE2 16S rRNA methyltransferase gene conferring resistance to aminoglycosides in Escherichia coli. [rmtE2] (Mus musculus) PubMed

 17287.

the first 18 amino acids of the negatively charged N-terminal LdAAP24 tail are required for alanine transport and may facilitate the electrostatic interactions of the entire negatively charged N-terminal tail with the positively charged internal loops (Mus musculus) PubMed

 17288.

NpmA possesses dual m1A1408/m1G1408 specificity. [NpmA] (Mus musculus) PubMed

 17289.

Biochemical characterization of VIM-39, a VIM-1-like metallo-beta-lactamase variant from a multidrug-resistant Klebsiella pneumoniae isolate from Greece has been presented. [blaVIM-39] (Mus musculus) PubMed

 17290.

The selected CpG-E1E2-M4 mutant is a novel potential HCV DNA vaccine that elicits enhanced CD4(+) Th1 and CD8(+) T cell responses and neutralizing antibody production against HCV infection. (Mus musculus) PubMed

 17291.

Our results indicate that the combinations of Ghd7, Ghd8 and Hd1 largely define the ecogeographical adaptation and yield potential in rice cultivars. [GHD7, GHD8, HD1] (Mus musculus) PubMed

 17292.

study confirmed Hsp90 as an influenza virus A PB2 polymerase interacting protein, and established that Hsp90 interacts with both the E627 and 627K variants, but has established this interaction is species independent, and both mammalian and avian Hsp90 can bind to the PB2 protein [PB2] (Mus musculus) PubMed

 17293.

XseA protects chromosome as a component of the Exonuclease VII enzyme, but in some conditions, the protein causes cell death. (Mus musculus) PubMed

 17294.

UV-induced translational depression is largely independent of GCN2 and eIF2alpha phosphorylation. (Mus musculus) PubMed

 17295.

contributes to kernel development [GS5] (Mus musculus) PubMed

 17296.

A PmrB-regulated deacetylase NaxD required for lipid A modification and polymyxin resistance in Acinetobacter baumannii has been characterized. [PmrB]; [NaxD] (Mus musculus) PubMed

 17297.

Results showed that 65.5% of the studied Iranian individuals had positive IgG responses to two apical membrane antigen-1 of Plasmodium vivax (PvAMA-1) variants, and the prevalence of responders did not differ significantly. [AMA1] (Mus musculus) PubMed

 17298.

LycCatS and LycCatL are highly conserved to their teleost counterparts, and expressed in all tissues and immune-related cells tested, but at different levels. Cathepsin S may be the main cathepsin involved in Ii chain processing in fish.[Cathepsin L] (Mus musculus) PubMed

 17299.

The adaptation of the Split KalTA4 system should be useful for expression of genes-of-interest in an intersectional manner, allowing for more refined manipulations of cell populations in zebrafish. [KalTA4] (Mus musculus) PubMed

 17300.

crystal structures of the FeII/alpha-ketoglutarate-dependent dioxygenase AsqJ, in the absence and presence of synthesized substrates, surrogates, and intermediates that mimic the various stages of the reaction cycle [AsqJ] (Mus musculus) PubMed

 17301.

determined crystal structures of full length and C-terminal truncated 2-deoxyribose-5-phosphate aldolase (DERA); results suggest that DERA might adopt a shorter C-terminal region than conventional aldolases during evolution pathway, resulting in a broader range of substrate tolerance through active site flexibility [DERA] (Mus musculus) PubMed

 17302.

flexibility and conformational changes in Ag85A, Ag85B, Ag85C and MPT51 were compared during the course of a molecular dynamics simulation (Ag85A, Ag85B, Ag85C and MPT51) (Mus musculus) PubMed

 17303.

the differential processing of BprL, either heterocatalytically or autocatalytically, leads to the formation of multiple mature forms with different molecular masses or conformations. [Bpr; Bacillopeptidase F]. (Mus musculus) PubMed

 17304.

attachment and were susceptible to lysozyme CotE has a role in the assembly of both the coat and exosporium, which is more important during sporulation at 20 degrees C. [CotE]. (Mus musculus) PubMed

 17305.

this work identifies fimbrin as a key target for cell cycle regulation of actin cable assembly in budding yeast, and suggests an underlying mechanism.[Fimbrin, Cdk1] (Mus musculus) PubMed

 17306.

The prevalence of OXA-10, as well as mexR and nfxB efflux regulator genes in clinical isolates of P. aeruginosa in Nigeria. [Oxa-10] [mexr] [nfxb] (Mus musculus) PubMed

 17307.

the first three-dimensional structure of Apergillus flavus-derived glucose dehydrogenase using flavin adenine dinucleotide (FAD) as the cofactor, is reported.[Glucose dehydrogenase] (Mus musculus) PubMed

 17308.

A structural view of the dissociation of Escherichia coli and Proteus vulgaris tryptophanase subunits has been presented. [tryptophanase] (Mus musculus) PubMed

 17309.

The first crystal structure of the peptidase domain of the U32 peptidase family (gene mk0906) has been presented. [U32 peptidase] (Mus musculus) PubMed

 17310.

Atomic resolution crystal structure of Sapp2p, a secreted aspartic protease from Candida parapsilosis has been presented. [Sapp2p] (Mus musculus) PubMed

 17311.

Structure-function relationships in Gan42B, an intracellular GH42 beta-galactosidase from Geobacillus stearothermophilus, has been reported. [Gan42B] (Mus musculus) PubMed

 17312.

MicroRNA-92a regulates expression of KLF2 in a rabbit model of intracranial aneurysm. [microRNA 92]; [Klf2] (Mus musculus) PubMed

 17313.

Data suggest the transition state of active-site-bound allolactose, a natural substrate of lacZ, has (4)H(3) conformation and migrates from a shallow to a deep binding site; His418 of lacZ is important in this positioning. [lacZ, beta-galactosidase] (Mus musculus) PubMed

 17314.

PBP2c protein does not mediate resistance to penicillin in methicillin- resistant Staphylococcus aureus[pbp2c] (Mus musculus) PubMed

 17315.

FRI-1 gene was located on a ca. 110-kb untypeable, transferable, and non-self-conjugative plasmid and plays a role in carbapenem resistance.[FRY-1] (Mus musculus) PubMed

 17316.

study found that PhoP and the nitrogen regulator GlnR both regulate the transcription of glnR as well as other nitrogen metabolism-related genes.[PhoP; GlnR] (Mus musculus) PubMed

 17317.

Data suggest lacZ exhibits dynamic heterogeneity due to conformational changes in individual molecules that results in differences in catalytic rate and electrophoretic mobility; conformational changes appear to be subtle. [lacZ, beta-galactosidase] (Mus musculus) PubMed

 17318.

the cellular localization of two glycolytic enzymes in the anaerobic pathogen Trichomonas vaginalis: PPi-dependent phosphofructokinase, which is the main glycolytic PFK activity of the protist, and ATP-dependent PFK, is reported.[TvATP-PFK, TvPPi-PFK] (Mus musculus) PubMed

 17319.

We show that Leo1-Paf1 [a subcomplex of the RNA polymerase II-associated factor 1 complex (Paf1C)] is required to prevent the spreading of heterochromatin into euchromatin.[Leo1-Paf1]. (Mus musculus) PubMed

 17320.

LiaR plays a relevant role in the Enterococcus faecium cell membrane adaptive response to antimicrobial peptides independent of the genetic background [Liar] (Mus musculus) PubMed

 17321.

A high-throughput genetic screen revealed that vesicle-mediated transport between Golgi apparatus, endosomes, and vacuole becomes crucial for survival when Aur1 is repressed, irrespective of the mode of repression.[Aur1] (Mus musculus) PubMed

 17322.

Brl1 and two other proteins characterized previously-Brr6, which is closely related to Brl1, and Apq12-function together and are required for lipid homeostasis.[Brl1, Apq12, Brr6] (Mus musculus) PubMed

 17323.

Data suggest that Colletotrichum graminicola exhibits linoleate diol synthase with substrate specificity including oleic acid, linoleic acid, and alpha-linoleic acid. [LDS, EFQ34869; linoleate diol synthase] (Mus musculus) PubMed

 17324.

Quantitative analysis of pseudocontact shifts has identified a novel conformational state of MurD.[MurD] (Mus musculus) PubMed

 17325.

Cell lines that were depleted for Ubc9p did not form mating pairs and therefore could not complete any of the subsequent stages of conjugation, including meiosis and macronuclear development.[Ubc9p] (Mus musculus) PubMed

 17326.

Data suggest that transcription factor WRKY53 (OsWRKY53, Os05g27730) enables rice plants to control the magnitude of their defensive investment during early signaling: [OsWRKY53] (Mus musculus) PubMed

 17327.

review of current understanding of Pi-ta allelic variation, its linkage with rice productivity, AVR-Pita allelic variation, and the coevolution of Pi-ta and AVR-Pita in Oryza species and Magnaporthe oryzae populations, respectively [AVR-Pita1] (Mus musculus) PubMed

 17328.

Findings indicate that SPX-Major Facility Superfamily3 (OsSPX-MFS3) is a low-affinity phosphate (Pi) transporter that mediates Pi efflux from the vacuole into the cytosol: [OsSPX-MFS3] (Mus musculus) PubMed

 17329.

GUDK has the potential to regulate grain yield both under favorable and unfavorable conditions.[GUDK] (Mus musculus) PubMed

 17330.

A new bursal peptide (BP-IV) was isolated from BF, which promoted colony-forming unit pre-B formation and regulated B cell differentiation. BP-IV also exerted immunomodulatory effects on antigen-specific immune responses.[BP-IV] (Mus musculus) PubMed

 17331.

OsCYP19-4 is required for developmental acclimation to environmental stresses, especially cold. There is potential of manipulating OsCYP19-4 expression to enhance cold tolerance or to increase biomass.[CYP 19-4] (Mus musculus) PubMed

 17332.

Overexpression of ZFP185 in rice results in a semi-dwarfism phenotype, reduced cell size, and the decrease of endogenous GA3 gibberellin (GA3) content. By contrast, higher GA3 content was observed in RNAi plants.[ZFP185] (Mus musculus) PubMed

 17333.

The expression level of serum PGA1 decreased in chronic atrophic gastritis with intestinal metaplasia group and gastric cancer group. [PGA1] (Mus musculus) PubMed

 17334.

HBV DNAPTP1 downregulated the expression of SWI5 and CTC1 at translation level. [DNAPTP1] (Mus musculus) PubMed

 17335.

HBZ plays a critical role in the leukemogenesis of T-cell leukemia. [review][HBZ protein] (Mus musculus) PubMed

 17336.

The presence of the tin gene and its likely role in modifying tiller number has slowed and deferred water use while maintaining grain number, and contributed to changes in seminal and branch root length to increase total root length and biomass.[tin] (Mus musculus) PubMed

 17337.

The data indicate that the structural change at position 425 of cytochrome c oxidase propagates to the D proton pathway, which suggests a link between redox changes at heme a and modulation of intramolecular proton-transfer rates.[Cytochrome c oxidase] (Mus musculus) PubMed

 17338.

identification of two additional AP lyase active sites in topoisomerase V ( topoisomerase V). (Mus musculus) PubMed

 17339.

Wigglesworthia glossinidia thymidylate synthase (TS) has the minimal activity necessary to support replication of its reduced genome. [TS] (Mus musculus) PubMed

 17340.

results suggest a possible role of Hp0897 in loading of DnaB at replication origin (DnaB) (Mus musculus) PubMed

 17341.

The recombinant production, purification and crystallization of an inactive variant of CT441, designated CT441 degrees (active-site Ser455 replaced by Ala), are described.[CT441] (Mus musculus) PubMed

 17342.

the ZnuA domain of AdcA was crystallized.[AdcA] (Mus musculus) PubMed

 17343.

Crystals of TaAlDHwt belonged to the monoclinic space group P1211 with eight molecules per asymmetric unit and diffracted to a resolution of 1.95 A.[TaAlDH] (Mus musculus) PubMed

 17344.

pd1 mapped between the simple sequence repeat markers RM11236 and RM11280 on rice chromosome 1. (Mus musculus) PubMed

 17345.

Hydrogen peroxide is the key player in the E. coli ChuS mediated heme degradation reaction, at variance to canonical heme oxygenases. (Mus musculus) PubMed

 17346.

OsWS1 is regulated by osa-miR1848 and participates in cuticular wax formation. [OsWS1 and osa-miR1848] (Mus musculus) PubMed

 17347.

D14 is destabilized upon the binding of ligands and D3, thus revealing an unusual mechanism of SL recognition and signaling, in which the hormone, the receptor, and the downstream effectors are systematically destabilized during the signal transduction process. [Dwarf 14, Dwarf 3] (Mus musculus) PubMed

 17348.

Results suggested that gibberellin-mediated expression of the sodCp gene in aleurone layers is associated with histone hyperacetylation on the promoter and coding region of this gene, consequently leading to an accumulation of hydrogen peroxide which regulated production of alpha-amylase during seed germination.[sodCp] (Mus musculus) PubMed

 17349.

results indicate that MG491 plays a key role in the functioning, organization and stabilization of the terminal organelle (MG491). (Mus musculus) PubMed

 17350.

FarR2 bound to the FarA-binding sequences in the promoter regions of the regulatory genes that were downregulated by FarR2 [FarR2] (Mus musculus) PubMed

 17351.

ONAC106 functions in leaf senescence, salt stress tolerance and plant architecture by modulating the expression of its target genes that function in each signaling pathway.[ONAC106] (Mus musculus) PubMed

 17352.

Study provides evidence for dfrG been the predominant determinant of trimethoprim resistance in human Staphylococcus aureus infection. [dfrG] (Mus musculus) PubMed

 17353.

Overall we conclude that centrosome position controls spindle activity and that TgEB1 is critical for mitotic integrity (Mus musculus) PubMed

 17354.

Dictyostelium ATG8a and ATG8b have distinct functions in autophagosome formation[ ATG8a and ATG8b] (Mus musculus) PubMed

 17355.

There is a glutamine-dependent control of NAGK by PII. Glutamine synthetase catalyzes the ATP-dependent conversion of glutamate and ammonium to glutamine.[NAGK,PII,GS] (Mus musculus) PubMed

 17356.

The identified binding sites in the P. furiosus genome classified TrmBL1 as a more global regulator as hitherto known. (Mus musculus) PubMed

 17357.

The sequence of Px5 from all resistant inbreds was identical, except for one base change in two inbreds, only one of which affected the amino acid sequence. Conversely, the Px5 sequence from several susceptible inbreds had several base variations.[Px5] (Mus musculus) PubMed

 17358.

TGF-beta-activated kinase [TAK1] played important roles in Advanced glycation end products-induced mitogen-activated protein kinases (MAPKs) and nuclear factor kappa B protein (NF-kappaB) activation. (Mus musculus) PubMed

 17359.

Suggest mycobacterium tuberculosis PpiA-specific IFN-gamma and IFN-gamma/TNF-alpha ratio responses as specific biomarkers for latent tuberculosis infection identification. (Mus musculus) PubMed

 17360.

PsCRN161 expression may protect plants from biotic and abiotic stresses by up-regulation of many defense-related genes.[PsCRN161] (Mus musculus) PubMed

 17361.

No-OsHKT2;2/1 could mediate destructive Na(+) influx over K(+) uptake in Nona Bokra plants upon salinity stress, and a predominant physiological function of No-OsHKT2;2/1 might be the acquisition of Na(+) and K(+) in K(+)-limited environments.[HKT2;2/1] (Mus musculus) PubMed

 17362.

The patterns of norV and Shiga toxin genotypes in Escherichia coli isolates in Yamaguchi prefecture, Japan, are reported.[NorV; STX] (Mus musculus) PubMed

 17363.

It was found that loss of yadBC caused a modest loss of invasiveness for epithelioid cells and a large decrease in virulence for bubonic plague but not for pneumonic plague in mice. (Mus musculus) PubMed

 17364.

[p39] p39 suppresses type 1 IFN production by preventing IRF-3 activation (Mus musculus) PubMed

 17365.

These results will improve our understanding of the catalytic mechanism of FadD32 and help in the design of inhibitors of this essential enzyme. (Mus musculus) PubMed

 17366.

Dectin-2 is intimately involved in the host defense against infection with a serotype 3 strain of S. pneumoniae.[Dectin-2] (Mus musculus) PubMed

 17367.

a knock-out in the leukotoxin structural gene, ltxA, has an effect on attachment related virulence genes in A. actinomycetemcomitans ( ltxA). (Mus musculus) PubMed

 17368.

Thus, activation of rpoS transcription by BosR somehow involves Arg39.[rpoS, BosR] (Mus musculus) PubMed

 17369.

The interaction of VP3 and RPL4 is involved in regulating the replication of infectious bursal disease virus. (Mus musculus) PubMed

 17370.

Immediate-early protein-mediated full trans-activation requires a consensus TATA box of core promoters. [immediate-early protein] (Mus musculus) PubMed

 17371.

HU proteins are translated from leaderless mRNA. [HU] (Mus musculus) PubMed

 17372.

The effects of mutations of the cytochrome b subunit (petB gene) confirms predictions that mutations located at the cytochrome b-head domain of iron-sulfur protein (ISP-HD) interface influence the motion of ISP-HD (cytochrome b subunit (petB gene). (Mus musculus) PubMed

 17373.

PecS indirectly and negatively regulates the expression of type 1 fimbriae. [pecS] (Mus musculus) PubMed

 17374.

the impaired function of OsCDC48 was responsible for the premature senescence and death phenotype.[OsCDC48] (Mus musculus) PubMed

 17375.

In summary, these data indicate that RsmA controls virulence by integration of its regulatory activities at various levels.[RsmA] (Mus musculus) PubMed

 17376.

the Ccl1-Kin28 complex regulates the expression of Atg29 and Atg31, which is crucial in the assembly of the Atg1 kinase complex.[Ccl1, Kin28] (Mus musculus) PubMed

 17377.

the localisation of apical membrane antigen 1 (AMA1) at the merozoite-erythrocyte junction and predicts that the merozoite thrombospondin-related anonymous protein (MTRAP) is unlikely to play a direct role in the mechanics of entry.[AMA1, MTRAP] (Mus musculus) PubMed

 17378.

The expression of hns itself was subjected to temperature regulation, where hns was expressed more at 26 than at 37 .[hns] (Mus musculus) PubMed

 17379.

Hsp60 interacts with Calpain in Plasmodium falciparum infected red blood cells.[Hsp60 and Calpain] (Mus musculus) PubMed

 17380.

AoS28A and AoS28B very efficiently digested the proline-rich 33-mer of gliadin. [AoS28A] (Mus musculus) PubMed

 17381.

The authors demonstrate that, in addition to MyD88, Yersinia pseudotuberculosis inhibits TRIF signaling through the type III secretion system effector YopJ.[YopJ] (Mus musculus) PubMed

 17382.

The authors show that the Ca(2+)-dependent protein kinase CDPK2 is a critical regulator of amylopectin metabolism.[CDPK2] (Mus musculus) PubMed

 17383.

gp40 does not impair the folding or high-affinity peptide binding of the class I molecules but binds to them, leading to their retention in the secretory pathway.[gp40] (Mus musculus) PubMed

 17384.

MaLBD5 and MaJAZ1 act antagonistically in relation to MeJA-induced cold tolerance of banana fruit.[JAZ1, LBD5] (Mus musculus) PubMed

 17385.

OsCCX2 having distinct metal transport properties than previously characterized plant calcium cation exchangers.[OsCCX2] (Mus musculus) PubMed

 17386.

These data support a model wherein a copper-trafficking pathway and Tat-dependent secretion of DtpA link to the GlxA-dependent morphogenesis pathway.[DtpA, GlxA] (Mus musculus) PubMed

 17387.

These data suggested that A184S improves the ability against UV radiation and mitomycin C shock, providing new insights into the modification of IrrE. (Mus musculus) PubMed

 17388.

Ail-expressing Yersinia pestis strains bind vitronectin - a host protein with functions in cell attachment, fibrinolysis and inhibition of the complement system.[Ail] (Mus musculus) PubMed

 17389.

These results show that NsrR regulates different promoters in response to different concentrations of NO. Spectroscopic evidence indicates that this is achieved by different NO-FeS complexes. (Mus musculus) PubMed

 17390.

Saccharomyces cerevisiae (Mus musculus) PubMed

 17391.

Hsp18 gene expression is involved in heat shock and acid shock response. [hsp18] (Mus musculus) PubMed

 17392.

In vivo TdsPLA2II and TdsPLA2III are differently regulated at both molecular and biochemical level and TdsPLA2III plays a major role in durum wheat response to adverse environmental conditions.[sPLAII,sPLAIII] (Mus musculus) PubMed

 17393.

The Master Transcription Factor mtfA Governs Aflatoxin Production, Morphological Development and Pathogenicity in the Fungus Aspergillus flavus [mtfA] (Mus musculus) PubMed

 17394.

TdrA encoded a novel dichloroethene dehalogenase and located on a genomic island. [tdrA] (Mus musculus) PubMed

 17395.

The results obtained support a role in polar localization for the central polar-targeting region and contend the role of the N-terminal polar-targeting region.[IcsA] (Mus musculus) PubMed

 17396.

CgrA thus constitutes a novel variant of catabolite repressor protein that utilizes cGMP to regulate production of cGMP synthase for the control of cyst development.[CgrA] (Mus musculus) PubMed

 17397.

Study proves that CART1 is expressed in both cephalic lobe and caudal lobe of chicken anterior pituitaries under the control of the hypophysiotropic factors. [CART1} (Mus musculus) PubMed

 17398.

Together, these findings identify amino acid regions in HypC accessory proteins that specify interaction with the large subunits of hydrogenase and demonstrate functional compatibility of Hyp accessory protein machineries.[HypC] (Mus musculus) PubMed

 17399.

Under apoptotic-like programmed cell death conditions. bir1 shuttled to the cytoplasm and then it was completely degraded.[bir1] (Mus musculus) PubMed

 17400.

Amino acid sequences 63-77 and 96-110 of GapC are CD4 T-cell epitopes. [GapC] (Mus musculus) PubMed

 17401.

the biochemical characterization of the homologue of Werner (Wrn) helicase from P. falciparum 3D7 strain, is reported. (Mus musculus) PubMed

 17402.

Findings from the measurement of Helicobacter pylori babA2 and vacA genotypes indicate a strong correlation between the vacA i1 allele and gastric cancer risk in the Azerbaijan area of Iran. [vacA] and [babA2] (Mus musculus) PubMed

 17403.

the beta-class carbonic anhydrase of Methanobacterium thermoautotrophicum, was investigated.[beta Carbonic anhydrase] (Mus musculus) PubMed

 17404.

The expression of toll-like receptor 10 (TLR-10) in the lungs of multiples species, including chickens, is reported.[TLR-10] (Mus musculus) PubMed

 17405.

Results show that SSB localizes PriA and RecG to the vicinity of the inner membrane in the absence of DNA damage. Localization requires that SSB be in excess over the DNA helicases and the SSB C-terminus and both PriA and RecG be present. [recG and PriA] (Mus musculus) PubMed

 17406.

hsa1 mutations cause sterility in rice. [hsa1] (Mus musculus) PubMed

 17407.

new data on the conservation of See1 in other closely related smuts, is presented.[See1] (Mus musculus) PubMed

 17408.

The authors describe a role for RefZ, a DNA-binding protein that regulates FtsZ, and its cognate binding motifs (RBMs) in defining the specific region of chromosome initially captured in the forespore.[RefZ] (Mus musculus) PubMed

 17409.

The authors show that TgASP5 is essential for GRA16 export, is directly responsible for its maturation in a Plasmodium export element-dependent manner and is also involved in GRA24 export.[TgASP5, GRA16, GRA24] (Mus musculus) PubMed

 17410.

ROP18 and the combination of ROP18/ROP5 alleles are associated with T. gondii virulence in mice [ROP18][ROP5] (Mus musculus) PubMed

 17411.

These findings show for the first time that CcoA-mediated Cu import relies on conserved Met and His residues that could act as metal ligands at the membrane-embedded Cu binding domain of this transporter.[CcoA] (Mus musculus) PubMed

 17412.

The authors found that human adenovirus 5 infection or ectopic E4-ORF3 expression leads to SUMOylation of TFII-I that precedes a rapid decline in TFII-I protein levels.[E4-ORF3 (Mus musculus) PubMed

 17413.

Here, the authors identify Ssn6, the Candida albicans functional homolog of the Saccharomyces cerevisiae transcriptional corepressor Cyc8, as a new regulator of white-opaque switching.[Ssn6] (Mus musculus) PubMed

 17414.

The results of the biochemical and biophysical characterization indicate that CcoM may be involved in Cytochrome c oxidases complex assembly or stabilization.[CcoM] (Mus musculus) PubMed

 17415.

Genetic epistasis analysis in suggests that NreA works together with the UvrABC proteins in repairing DNA damage resulting from exposure to mitomycin C.[NreA, UvrABC] (Mus musculus) PubMed

 17416.

the BDNF/TrkB pathway facilitates persistent activity whereas the proBDNF/p75NTR pathway inhibits this mnemonic property of entorhinal pyramidal neurons.[proBDNF] (Mus musculus) PubMed

 17417.

Inactivation of bnaG abolished the growth of L. casei on lacto-N-triose. [bnaG] (Mus musculus) PubMed

 17418.

[Nsp2alpha] the non-structural protein 1 alpha (Nsp1alpha) of PRRSV is a negative regulator of p53 activity through increasing mdm2 expression and p53 ubiquitination. (Mus musculus) PubMed

 17419.

Immunogold labeling determined that ClpB and ClpC localized on the flagella surface[ClpB, ClpC] (Mus musculus) PubMed

 17420.

Full nitric oxide production requires a functional nitrate reductase (NR) gene (niaD) that is upregulated upon induction of conidiation, even under N-repressing conditions in the presence of ammonium.[NiaD] (Mus musculus) PubMed

 17421.

These results demonstrate that VvpE plays important role in promoting the tight junction disruption and intestinal colonization of Vibrio.[VvpE] (Mus musculus) PubMed

 17422.

molecular cloning and characterization of extremely thermostable (+)-gamma-lactamase from Sulfolobus solfataricus P2 (Mus musculus) PubMed

 17423.

we have investigated the processing of the FPPS/GGPPS transcript in P. falciparum by high-throughput sequencing methods in four time-points along the intraerythrocytic cycle of P. falciparum (Mus musculus) PubMed

 17424.

two putative genes encoding hexokinase in F. graminearum (FgHXK1 and FgHXK2), which is a rate-limiting enzyme in deoxynivalenol biosynthesis, were identified.[HXK1, HXK2] (Mus musculus) PubMed

 17425.

Fbp1 is required for full phosphorylation of Fmk1, indicating that Fbp1 regulates virulence and invasive growth via the Fmk1 pathway.[Fbp1, Fmk1] (Mus musculus) PubMed

 17426.

SHP peptide pheromone degradation is mediated by the cytoplasmic endopeptidase PepO, which is the first identified enzymatic silencer of an RRNPP-type quorum-sensing pathway.[PepO] (Mus musculus) PubMed

 17427.

Upon lytic cycle induction, CI is partially degraded, cro-gp25 mRNA levels increase, and Cro accumulates, launching viral progeny production. [Gp25] (Mus musculus) PubMed

 17428.

LhaA and PucC are important for specific assembly of LH1 or LH2 complexes.[LhaA] (Mus musculus) PubMed

 17429.

The authors have generated several CdtB mutants and demonstrate that, in each instance, the ability of the toxin to induce cell cycle arrest correlates with retention of phosphatase activity.[CdtB] (Mus musculus) PubMed

 17430.

These data identify Toxoplasma gondii GRA7 as a regulator for ROP18-specific inactivation of murine Irga6.[GRA7, ROP18] (Mus musculus) PubMed

 17431.

mef(A) and msr(D) are involved in macrolide resistance in S. pyogenes.[mefA and msrD] (Mus musculus) PubMed

 17432.

BGA66 and BGA71 bind complement components C7, C8 and C9, and thereby prevent assembly of the terminal complement complex. [BGA66,BGA71] (Mus musculus) PubMed

 17433.

GtfC is inactive with sucrose and displays 4,6-alpha-glucanotransferase activity with malto-oligosaccharides.[GtfC] (Mus musculus) PubMed

 17434.

Knockout of any of the genes hycE, hycF, or hycG eliminates hydrogenase-3 and inhibits the NADH hydrogen production pathway. The NADH/NAD(+) ratio of the mutant strains increased nearly 1.4-fold compared with the wild type (hycE, hycF, and hycG). (Mus musculus) PubMed

 17435.

A523R and N540R mutations of Neq DNA polymerase had synergistic effects on its fidelity. Dna polymerase. (Mus musculus) PubMed

 17436.

The moderately thermotolerant alkaline lipase exhibited hydrolytic activity at extreme pH levels and a broad range of substrate specificity (alkaline lipase). (Mus musculus) PubMed

 17437.

Competitive ELISA assays confirmed the involvement of sulfated epitopes in the affinity between Siglec-E and cruzipain, probably modified by natural protein environment.[Cruzipain] (Mus musculus) PubMed

 17438.

FlhG influences FlhF GTPase activity, which may mechanistically contribute to flagellar number regulation. [FlhF, FlhG] (Mus musculus) PubMed

 17439.

The LAMP assay was compared to a p30-based PCR assay, using DNA extracted from EDTA-anticoagulated blood samples of 137 dogs from an endemic region in Brazil. (Mus musculus) PubMed

 17440.

Mutation studies of N-acetyl glutamate kinase also revealed that amino acid residues 18-23 of the N-helix are required for inhibition by L-arginine.[N-acetyl glutamate kinase] (Mus musculus) PubMed

 17441.

Lack of HrtA protein potentiates the phototoxic effect towards S. aureus but only when extracellular protoporphyrin IX is used. [HrtA] (Mus musculus) PubMed

 17442.

Gnasxl deficiency does not directly affect glial development in the hypothalamus, since it is expressed in neurons, and Gfap-positive astrocytes and tanycytes appear normal during early postnatal stages.[Gnasx1] (Mus musculus) PubMed

 17443.

These results indicate that Gam does inhibit the RecBCD exonuclease in Klebsiella pneumoniae, but that this inhibition is not stringent.[Gam, RecBCD] (Mus musculus) PubMed

 17444.

The maize homolog of Arabidopsis EBP1, ZmEBP1, displayed an overdominant expression pattern in the Zong3/87-1 hybrid. This gene was upregulated in immature ears of the reciprocal hybrids Zong3/87-1 and 87-1/Zong3 at different developmental stages.(EBP1) (Mus musculus) PubMed

 17445.

EpsW, an orphan and single-domain response regulator (RR), was identified as a potential DifE target first by bioinformatics.[EpsW, DifE] (Mus musculus) PubMed

 17446.

The oligomerization of CssA-CssB depends on both subunits in equal stoichiometry. [CssB] (Mus musculus) PubMed

 17447.

The tsr(H258Y) gene served as a selectable marker for plasmid transformation of G. kaustophilus. [tsr] (Mus musculus) PubMed

 17448.

findings suggest Abo1 provides a histone chaperone function that maintains nucleosome architecture genome-wide [Abo 1] (Mus musculus) PubMed

 17449.

These results showed that CHU_2981, the periplasmic non-cellulolytic protein, plays an important role in both cellulose utilization and cell motility probably by being involved in the appropriate production of outer membrane proteins.[CHU_2981] (Mus musculus) PubMed

 17450.

H-NS protein suppresses pilE intragenic transcription as well as antigenic variation through the pilE/pilS recombination system. [pile, H-NS] (Mus musculus) PubMed

 17451.

a miR482-mediated silencing cascade mechanism is involved in regulating potato resistance against V. dahliae infection.[miR482e] (Mus musculus) PubMed

 17452.

SLAC7 is essential for maintaining the chloroplast stability in rice.[SLAC7] (Mus musculus) PubMed

 17453.

pMGA interacts with host apolipoprotein A-I during infection in chicken. [pMGA] (Mus musculus) PubMed

 17454.

HBZ plays an essential role in oncogenesis by regulating viral transcription and modulating multiple host factors that contribute to the development of cancer. [HBZ][review] (Mus musculus) PubMed

 17455.

A disulfide-clasped fucose binding loop directs BabA adherence to host ABO/Le(b) blood group. [BabA] (Mus musculus) PubMed

 17456.

Using a high throughput screening approach, the authors identified a chemoreceptor from Pseudomonas putida KT2440, named McpH, which specifically recognizes purine and its derivatives, adenine, guanine, xanthine, hypoxanthine and uric acid.[McpH] (Mus musculus) PubMed

 17457.

Rice alpha-fucosidase active against plant complex type N-glycans containing Lewis a epitope has been characterized. [alpha-fucosidase] (Mus musculus) PubMed

 17458.

the characterization of a SNARE homologue, FgVam7, from Fusarium graminearum that causes head blight in wheat and barley worldwide, is reported.[FgVam7] (Mus musculus) PubMed

 17459.

The H25 and H37 residues at the ferroxidase Dps are not strictly required for metal binding and oxidation. [Dps] (Mus musculus) PubMed

 17460.

[SurA1] SurA1 plays an important role in the fitness and virulence of A. baumannii. (Mus musculus) PubMed

 17461.

ALDH1 is a valid cancer stem cell marker for VX2 cancer.[ALDH1] (Mus musculus) PubMed

 17462.

[chondroitinase ac] the expression of chondroitinase AC by H. bizzozeronii is likely the consequence of adaptation of this bacterium to its host and a potential link to gastric disorders in dogs. (Mus musculus) PubMed

 17463.

Environment-induced conformational and functional changes of L-2-haloacid dehalogenase (Mus musculus) PubMed

 17464.

Identification, cloning, sequencing and expression of a rpf-like gene from Mycobacterium avium suggest that RpfA is present in this species also, which might be involved in reactivation phenomenon in this high-risk pathogen.[RpfA] (Mus musculus) PubMed

 17465.

HipH catalyzed the hydroxylation of 4-hydroxyisophthalate to protocatechuate.[HipH] (Mus musculus) PubMed

 17466.

In vitro studies revealed that the presence of DNA promotes amyloid formation by PSM peptides.[PSM] (Mus musculus) PubMed

 17467.

the ligand-bound form of FecB has greater thermal stability than ligand-free FecB under all pH and ligand conditions tested,[FecB] (Mus musculus) PubMed

 17468.

A 3D model of CaesCCR11 was predicted using the Bacillus sp. monoacyl glycerol lipase bMGL H-257 structure as template (Mus musculus) PubMed

 17469.

Report shows the structure of the PrtV N-terminal domain with two alpha-helices held together by hydrophobic residues. A third helical structure seems disordered. These residues are highly conserved suggesting a functional importance. [PrtV] (Mus musculus) PubMed

 17470.

molecular cloning and characterization of a thermophilic 1,3-1,4-beta-glucanase from Bacillus methylotrophicus S2 (Mus musculus) PubMed

 17471.

7-cyano-7-deazaguanine incorporation into tRNA by ArcTGT takes place early in the archaeal tRNA modification process.[ArcTGT] (Mus musculus) PubMed

 17472.

Described is the structure and characterization of the siderophore periplasmic binding protein, FscJ from the fuscachelin gene cluster of T. fusca. [FscJ] (Mus musculus) PubMed

 17473.

These results suggest that the cwf14 plays a key role in fission yeast morphogenesis and cell wall biosynthesis and/or degradation possibly via the regulation of Rho1 expression.[cwf14, Rho1] (Mus musculus) PubMed

 17474.

miR-1890 controls JHA15 mRNA stability in a stage- and tissue- specific manner.[JHA15, miR 1890] (Mus musculus) PubMed

 17475.

the role of the Ig-like domain on the activity, stability, and structural rigidity of AaCel9A and the effect of calcium on enzyme activity and stability were examined (Mus musculus) PubMed

 17476.

Overexpression of CsrA demonstrated the inhibition of growth and conidiation, while conidia specific long natural-antisense RNA did not affect conidiation. [CsrA] (Mus musculus) PubMed

 17477.

CupA and CopA may interact and filling of the CupA S2 site with Cu(i) results in stimulation of cellular copper efflux by CopA.[CupA] (Mus musculus) PubMed

 17478.

Streptococcus pyogenes toxin NAD glycohydrolase elicits necrosis through two different mechanisms depending on its NADase activity, i.e., metabolic (NADase(+)) or programmed (NADase(-)) via JNK1 activation.[NAD glycohydrolase] (Mus musculus) PubMed

 17479.

DcuS is a C4-dicarboxylate) sensor kinases. [DcuS] (Mus musculus) PubMed

 17480.

These data further indicate that regulation by two Sec1/Munc-18 proteins, Vps45 in early endosomes and Vps33 in early and late endosomes/vacuoles contributes to the wide domain of PepA(Pep12) action.[Vps45, Vps33, PepA(Pep12)] (Mus musculus) PubMed

 17481.

CitA is a citrate sensor kinases. [CitA] (Mus musculus) PubMed

 17482.

SdbA single cysteine variants at the N or C-terminal position were active but displayed different susceptibility to oxidation, and N-terminal cysteine was prone to sulfenylation. [sdbA] (Mus musculus) PubMed

 17483.

Although PRMT1's primary biological function was previously proposed to be methylation of histones, our studies suggest that PRMT1 plays an important role within the centrosome to ensure the proper replication of the parasite.[PRMT1] (Mus musculus) PubMed

 17484.

MYR1 is a novel protein that plays a critical role in how Toxoplasma delivers effector proteins to the infected host cell and that this is crucial to virulence.[MYR1] (Mus musculus) PubMed

 17485.

Reverse transcriptase polymerase chain reaction (PCR) and real-time quantitative PCR showed a reduction in mRNA levels of the CLA1 homolog in all three species. (Mus musculus) PubMed

 17486.

Epidermal growth factor receptor is a key regulator of cellular redifferentiation after acute injury in renal proximal tubular cells [epidermal growth factor receptor] (Mus musculus) PubMed

 17487.

Cbl-b acts as a scaffolding molecule to coordinate the delivery of the BCR and TLR9 into subcellular compartments required for productively delivering BCR-captured ligands to TLR9.[BCR] (Mus musculus) PubMed

 17488.

N-myristoylated Cblin prevents DEX-induced skeletal muscle atrophy in vitro and in vivo, and N-myristoylated Cblin more effectively prevents muscle atrophy than unmodified Cblin [Cblin] (Mus musculus) PubMed

 17489.

PMCA4 is strongly expressed in rabbit corneal epithelium and its immunolocalization exhibits marked changes in distribution during the wound healing process.[PMCA4] (Mus musculus) PubMed

 17490.

Convergent data signify DDR2 as a novel critical player in ovarian function, which acts upon classical endocrine pathways in somatic, rather than germline, cells.[Ddr2] (Mus musculus) PubMed

 17491.

DDX5 positively regulates the replication of porcine reproductive and respiratory syndrome virus via its interaction with viral Nsp9 in vitro.[DDX5] (Mus musculus) PubMed

 17492.

DPF positively regulates CPS2 transcription through the N-boxes. In addition, DPF partly regulates CYP99A2 through the N-box. This study demonstrates that DPF acts as a master transcription factor in DP biosynthesis.[DPF] (Mus musculus) PubMed

 17493.

EcgA encoded an endopeptidase contributes to virulence of Salmonella enterica serovar Typhimurium. [EcgA] (Mus musculus) PubMed

 17494.

In this study, a putative tripartite ATP-independent periplasmic (TRAP) transporter, GaaPQM, is shown to be essential for the utilization of galacturonic acid.[GaaPQM] (Mus musculus) PubMed

 17495.

Toxoplasma gondii Toc75 Functions in Import of Stromal but not Peripheral Apicoplast Proteins. (Mus musculus) PubMed

 17496.

These data provide clear evidence that RsbX is a negative regulator of sigma(B) during the recovery period after a primary stress or in the stationary phase, thus affecting its survival under secondary stress.[RsbX, SigB] (Mus musculus) PubMed

 17497.

The authors found that the key residue of Acb1 for acyl binding, Y80, is critical for the proper subcellular localization and secretion of Acb1 and for cryptococcal morphogenesis.[Acb1] (Mus musculus) PubMed

 17498.

HtrA proteases were reversibly inhibited by ZnCl2 at all micro molar concentrations. [HtrA] (Mus musculus) PubMed

 17499.

SdrF mediates bacterial adhesion to collagen-coated substrates through both weak and strong bonds.[SdrF] (Mus musculus) PubMed

 17500.

study demonstrates that osrR plays a positive role in C. glutamicum cells exposed to oxidative and heat stressors; also provide evidence for the role of the osrR gene in developing H2O2 resistance[osrR] (Mus musculus) PubMed

 17501.

dek* is a weak mutant allele with decreased Reas1 function.[reas1] (Mus musculus) PubMed

 17502.

Lotus japonicus Ckx3 cytokinin oxidase/dehydrogenase gene is induced by Nod factor during the early phase of nodule initiation.[CKX3] (Mus musculus) PubMed

 17503.

Nax loci enhances the retrieval of Na(+) back into the root stele via HKT1;4 or HKT1;5, whilst the other reduces the rate of Na(+) loading into the xylem via SOS1.[Nax, SOS1] (Mus musculus) PubMed

 17504.

ptsP. which encodes enzyme I of the nitrogen-regulated phosphotransferase (PTS(Ntr)) system, as being important for cyclic-di-GMP production and for biofilm formation. [PtsP] (Mus musculus) PubMed

 17505.

Mechanistically, Hif-3alpha2 binds to beta-catenin and destabilizes the nuclear beta-catenin complex.[Hif-3alpha2] (Mus musculus) PubMed

 17506.

the single and double alanine substitution mutants in the N-terminal 15th leucine and 18th methionine of CMV 2b exhibit drastically attenuated virulence in wild-type plants.[2b] (Mus musculus) PubMed

 17507.

These results suggest that PsHint1 not only regulates chemotaxis by interacting with PsGPA1, but also participates in a Galpha-independent pathway involved in the pathogenicity of P. sojae.[PsHint1, PsGPA1] (Mus musculus) PubMed

 17508.

BE27 is able to enter into the cytosol and kill fungal cells, thus arresting the growth of the fungus.[BE27] (Mus musculus) PubMed

 17509.

Cmwc-1 gene inactivation results in thicker aerial hyphae, disordered fruit body development, a significant reduction in conidial formation, and carotenoid and cordycepin production.[Cmwc-1]. (Mus musculus) PubMed

 17510.

The HSPC280 is a nuclear protein which, when overexpressed in Neuro2a cells, it inhibited neuronal differentiation in vitro, suggesting its involvement in the mechanisms controlling neural progenitor cells proliferation. (Mus musculus) PubMed

 17511.

Phospholipase A1 (pldA) of the Outer Membrane of Psychrotrophic Yersinia pseudotuberculosis was characterized. (Mus musculus) PubMed

 17512.

two specific polymorphisms are responsible for functional differences between VvTPS24 alleles.[VvTPS24] (Mus musculus) PubMed

 17513.

VvSTO2 may be a key enzyme in the biosynthesis of (-)-rotundone in grapevines by acting as a alpha-guaiene 2-oxidase.[VvSTO2] (Mus musculus) PubMed

 17514.

Fic-1 is an AMPylating enzyme that targets GyrB to inhibit DNA replication and may target other proteins to regulate bacterial morphology (Mus musculus) PubMed

 17515.

ClpP proteases from E. coli, S. aureus, and human mitochondria exhibit preferences for certain amino acids in the P1, P2, and P3 positions . [ClpP] (Mus musculus) PubMed

 17516.

ClpP proteases from E. coli, S. aureus, and human mitochondria exhibit preferences for certain amino acids in the P1, P2, and P3 positions . [ClpP] (Mus musculus) PubMed

 17517.

Rht_NM9 has a negative effect on plant height and positive effects on effective tiller number and grain size. [Rht_NM9] (Mus musculus) PubMed

 17518.

TalinB and Rap1 is necessary for adhesion of Dictyostelium cells. [talinB] (Mus musculus) PubMed

 17519.

FipA is involved in the escape of F. novicida from its vacuole.[FipA] (Mus musculus) PubMed

 17520.

bmr6 lines were associated with higher reductions in acid detergent lignin compared to lines harboring the previously characterized bmr6-ref allele.[Bmr6] (Mus musculus) PubMed

 17521.

EutQ and EutP represent novel classes of acetate kinases involved in ethanolamine catabolism. [eutQ] (Mus musculus) PubMed

 17522.

These findings highlight the role of OsWRKY74 in modulation of phosphate homeostasis.[OsWRKY74] (Mus musculus) PubMed

 17523.

FLO7 is a unique plant regulator required for starch synthesis and amyloplast development within the peripheral endosperm and provide new insights into the spatial regulation of endosperm development in rice.[FLO7] (Mus musculus) PubMed

 17524.

KNQ1 gene, encoding a permease, is required for boron tolerance. [Knq1] (Mus musculus) PubMed

 17525.

Phosphorylation of OsBSK3 by OsBRI1 disrupts the interaction between its TPR and kinase domains, thereby increasing the binding between OsBSK3's kinase domain and BSU1.[OsBRI1, OsBSK3] (Mus musculus) PubMed

 17526.

ALK3 and ALK6 both contribute to the gene regulatory network that regulates dorso-ventral patterning.[ALK6] (Mus musculus) PubMed

 17527.

The OPG expression levels decreased while those of RANKL and RUNX2 increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue. [RANKL] (Mus musculus) PubMed

 17528.

Cloning and characterization of 5-enopyruvylshikimate-3-phosphate synthase from Pantoea species has been reported. (Mus musculus) PubMed

 17529.

CHK1 and CHK2 receptors can function in cytokinin perception.[CHK1, CHK2] (Mus musculus) PubMed

 17530.

the subapical endocytic collar is a prominent feature of hyphae of Neurospora crassa; findings show that MYO-1 is another key component of this endocytic collar.[MYO-1] (Mus musculus) PubMed

 17531.

Casein kinase 2 (CK2) phosphorylates Domain 3 of NS5A at multiple sites. Identified are four serine residues as substrates of CK2. [NS5A] (Mus musculus) PubMed

 17532.

Arabidopsis and rice (Oryza sativa) plants expressing TaSR presented higher salt tolerance than the controls, whereas AtSR mutant and RNA interference rice plants were more sensitive to salt. [TaSR] (Mus musculus) PubMed

 17533.

quantitative Real time-PCR confirmed the expression of Lotus and Medicago truncatula PT4 in the tips of non-mycorrhizal roots.[LjPT4] (Mus musculus) PubMed

 17534.

ASR1 and ASR5 act in concert and complementarily to regulate gene expression in response to Aluminum. [ASR1, ASR5] (Mus musculus) PubMed

 17535.

These findings illuminate the significant role of SUB1A in active physiological recovery upon desubmergence, a component of enhanced tolerance to submergence. (Mus musculus) PubMed

 17536.

quantitative Real time-PCR confirmed the expression of Lotus and Medicago truncatula PT4 in the tips of non-mycorrhizal roots. [MtPT4] (Mus musculus) PubMed

 17537.

Ferritin is dominant iron-bearing protein in Azospirillum brasilense. [ferritin] (Mus musculus) PubMed

 17538.

Stem-loop structure in the vacuolating cytotoxin [vacA] 5' UTR is an important determinant of vacA expression through stabilisation of the vacA mRNA transcript and this effect is of importance during conditions of environmental stress.[VacA]. (Mus musculus) PubMed

 17539.

Gamma-aminobutanoic acid [GABA] is metabolized by the pathogen during infection increasing its energy production, whereas the mutants accumulate GABA intracellularly resulting in decreased energy production.[GABA]. (Mus musculus) PubMed

 17540.

Identified and characterised a new component of the pH regulatory machinery, PacX.[PacX]. (Mus musculus) PubMed

 17541.

results suggest that Ve1 and Vel2 play major roles, whereas Vel3 plays a minor role in sporulation, morphogenesis, and cellulase expression [vel1,vel2,vel3] (Mus musculus) PubMed

 17542.

TaMDAR6 can therefore be considered a negative regulator of plant cell death and of wheat defense to Puccinia striiformis.[TaMDAR6] (Mus musculus) PubMed

 17543.

Grx1 plays a role in the regulation of the thermotolerance. [Grx1] (Mus musculus) PubMed

 17544.

Investigation demonstrated the antioxidative function of oxyR in V. parahaemolyticus and its possible roles in biofilm formation, cell mobility, and the protection of growth in heated rich medium.[oxyR]. (Mus musculus) PubMed

 17545.

findings demonstrated that the gene annotated as metA in fact encodes the L-serine O-acetyltransferase function and should be annotated as cysE.[CysE]. (Mus musculus) PubMed

 17546.

UVS9 gene was cloned. Predicted UVS9 protein is nearly twice as long as other XPG homologs, primarily due to unusually long spacer region. When compared to other XPG homologs, new conserved domain involved in TFIIH interaction was found in UVS9. (Mus musculus) PubMed

 17547.

Substitution of amino acids at the P2 position with Glu dramatically reduced the cleavage efficiency by 80% in PMV.[PMV] (Mus musculus) PubMed

 17548.

a 3.19 A resolution crystal structure of QDE-1(Tte) reveals a quasisymmetric dimer similar to QDE-1(Ncr) Further electron microscopy analyses confirm that QDE-1(Tte) occurs as a dimer in solution and retains this status upon interaction with a template (Mus musculus) PubMed

 17549.

the protein levels of Cdt2 and Cig2, two MBF target genes, are reduced in the absence of TORC2-Gad8 signaling. (Mus musculus) PubMed

 17550.

While Y240 and Y481 were required for the substrate binding, Y240 had additional roles in the processive degradation of crystalline beta-chitin, possibly in guiding a chitin chain into the catalytic cleft.[chitinase B] (Mus musculus) PubMed

 17551.

an allele of Spt16 (spt16-m) that has a defect in binding to H3-H4 and impairs their deposition onto DNA. [Spt16] (Mus musculus) PubMed

 17552.

Results revealed a role for ToxS in the stabilization of ToxR by protecting the virulence regulator from premature proteolysis. [ToxS, ToxR]. (Mus musculus) PubMed

 17553.

The nitrate-induced regulation of OpdQ was found to be dependent on the transcription factor NarL via the NarXL two-component system. [OpdQ] (Mus musculus) PubMed

 17554.

GacA is an essential monomeric enzyme in Group A Streptococcus and representative of monomeric RmlD enzymes in Gram-positive bacteria and a subset of Gram-negative bacteria.[GacA]. (Mus musculus) PubMed

 17555.

Using experimental binding free energy techniques alongside MD simulations and calculated binding free energies, the study explored aromatic-mediated carbohydrate interactions in family 18 S. marcescens processive chitinases ChiA and ChiB, ascribing roles to each of the aromatic residues directly interacting with a bound (GlcNAc)6 ligand. [ChiA, ChiB] (Mus musculus) PubMed

 17556.

Lem2 facilitates Rad3-mediated checkpoint signaling for Cds1 activation. (Mus musculus) PubMed

 17557.

the possibilities of using the highly promiscuous Candida Antarctica lipase B as a protein scaffold to redesign a Diels-Alderase has been explored by means of theoretical quantum mechanics/molecular mechanics (QM/MM) molecular dynamics simulations. (Mus musculus) PubMed

 17558.

Bcy1, the regulatory subunit of PKA from Saccharomyces cerevisiae, forms a homotetramer. [Bcy1] (Mus musculus) PubMed

 17559.

Pneumolysin Leu431 and Trp433 residues in domain 4 are involved in the binding of cholesterol as well as recognition of the cell membrane.[pneumolysin] (Mus musculus) PubMed

 17560.

identified a thiol-disulfide oxidoreductase (MdbA), whose structure exhibits a conserved thioredoxin-like domain with a CPHC active site; given its diverse cellular functions in cell division, pilus assembly and toxin production, propose MdbA is a component of the general oxidative folding machine in C. diphtheriae [MdbA] (Mus musculus) PubMed

 17561.

a total of 5,123 and 1,399 AGO1-enriched small RNAs, excluding miRNAs, were identified in Arabidopsis thaliana and rice (Oryza sativa), respectively. (Mus musculus) PubMed

 17562.

The importance of residue Trp23 and Trp87 side chains in binding and correct positioning of penicillin V acylase was confirmed. [ penicillin V acylase ] (Mus musculus) PubMed

 17563.

AgaR1 and AgaR2 are two novel N-acetyl-galactosamine utilization pathway. [AgaR1, AgaR2] (Mus musculus) PubMed

 17564.

data suggests that a minimal function of genomic island LGI1 is to increase the tolerance of L. monocytogenes to Quaternary Ammonium Compounds via emrE [emrE] (Mus musculus) PubMed

 17565.

Data suggest that the mutated alternative oxidase (AOX) transgene is a potentially useful tool in studies of the physiological effects of AOX expression: [AOX] (Mus musculus) PubMed

 17566.

Both RUL1 and RUM1 exhibit the canonical four domain structure of Aux/IAA proteins, are localized to the nucleus, are unstable, and have similar short half-lives of ~23min. They can be stabilized by specific mutations in the five amino acid degron sequence of domain II. Proteins encoded by both genes interact in vivo with auxin response factors (ARFs) such as ZmARF25 and ZmARF34 in protoplasts.[RUM1,RUL1] (Mus musculus) PubMed

 17567.

BadR directly influences the expression of both rpoS and bosR in Borrelia burgdorferi [Bb]. This newly recognized role for BadR to fine-tune the activation of the RpoN-RpoS pathway at strategic times in Bb's life cycle.[BadR]. (Mus musculus) PubMed

 17568.

As transcriptional level of bchV was upregulated at lower light intensity, the Chlorobaculum tepidum adapted to low-light environments by control of the bchV transcription. [BchV]. (Mus musculus) PubMed

 17569.

After anaphase entry, FEAR activation promotes kinetochore enrichment of Fin1-PP1, resulting in SAC disassembly at kinetochores.[Fin1, Bub1, PP1] (Mus musculus) PubMed

 17570.

the chromatin regulators condensin and Hmo1 redistribute within the ribosomal DNA upon starvation. (Mus musculus) PubMed

 17571.

findings strongly suggest that the ability of Cbp1 to actively program host-cell death is an essential step in H. capsulatum pathogenesis. [Cbp1] (Mus musculus) PubMed

 17572.

Residues W228 and Y233 help to define GIM-1 lactamase active-site architecture and interact with bound beta-lactam substrates.[GIM-1] (Mus musculus) PubMed

 17573.

The Asp20-to-Asn Substitution in the Response Regulator AdeR Leads to Enhanced Efflux Activity of AdeB in Acinetobacter baumannii. [ader] Adeb expression is regulated by AdeR [adeb] (Mus musculus) PubMed

 17574.

These data provide evidence that PNT1 is a cysteine peptidase that is required exclusively for maintenance of the trypanosome kinetoplast. (Mus musculus) PubMed

 17575.

Malaria-derived hemozoin exerts early modulatory effects on the phenotype and maturation of human dendritic cells.[hemozoin] (Mus musculus) PubMed

 17576.

This exo-beta-D-glucosaminidase [AorCsxA]-overexpressing P. pastoris strain is feasible for large-scale production of AorCsxA.[An exo-beta-D-glucosaminidase ]. (Mus musculus) PubMed

 17577.

The structure of a C48S mutant of TSA2 from S. cerevisiae that mimics the reduced state of the peroxidatic cysteine has been determined. [TSA2] (Mus musculus) PubMed

 17578.

The BamA POTRA3 domain is associated with BamB via hydrogen-bonding and hydrophobic interactions. [BamA] (Mus musculus) PubMed

 17579.

MRP2 protein is essential for complete development within hepatocytes.MRP2 is dispensable for asexual blood stages. [MRP2] (Mus musculus) PubMed

 17580.

MRP2 is essential for development of mature liver schizonts. [mrp2] (Mus musculus) PubMed

 17581.

propose that the Golgi/plastid MSD1 plays an important role in adaptation to heat stress [MSD1] (Mus musculus) PubMed

 17582.

These structural insights suggest the formation of a TtLysWZY ternary complex, in which the flexible C-terminal extension of TtLysW promotes the efficient transfer of the labile intermediate from the active site of TtLysZ to that of TtLysY during the sequential reactions catalyzed by TtLysZY. (Mus musculus) PubMed

 17583.

The Plasmodium translocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice. [EXP2] (Mus musculus) PubMed

 17584.

The C-terminal domain, sharing little identity with IMPases, is responsible for the substrate specificity (i.e. allows the enzyme to distinguish between HOLP and d-myo-inositol-1-phosphate). Structural features, mainly the presence of a conserved Asp(246), allow MtHPP to bind HOLP specifically. (Mus musculus) PubMed

 17585.

FcgammaR III ligation can inhibit the antiviral immune response to porcine reproductive and respiratory syndrome virus infection.[FcgammaR III] (Mus musculus) PubMed

 17586.

regulation of the melanogenic genes involves three pathway-specific transcription factors (TFs) that are clustered with bcpks12 or bcpks13 and other developmental regulators such as light-responsive TFs [bcpks12, bcpks13 ] (Mus musculus) PubMed

 17587.

Escherichia coli GroEL-ES work well in Rhodococcus and simultaneously possess protein-folding assistance functions and the ability to stabilize and reactivate the native NHases.[GroEL-ES]. (Mus musculus) PubMed

 17588.

CyaA-produced cAMP triggers macrophage apoptosis by the mitochondrial route. [Cyaa] (Mus musculus) PubMed

 17589.

we describe a novel S. sonnei adhesin, SSO1327 which is a multivalent adhesion molecule (MAM) required for invasion of epithelial cells and macrophages and for infection in vivo.[SSO1327]. (Mus musculus) PubMed

 17590.

Functional analysis in Trichoderma reesei showed that the transcription factor RON1 is a key activator of the N-acetylglucosamine [GlcNAc] gene cluster and essential for GlcNAc catabolism.[RON1]. (Mus musculus) PubMed

 17591.

results provide further detail on the structure and biosynthesis of complex N-glycans in an important human pathogen and provide a second example of the adaptation by trypanosomes of beta3-glycosyltransferase family members to catalyze beta1-2 glycosidic linkages. (Mus musculus) PubMed

 17592.

Like the tyrosine-rich proteins of the oocyst wall, Eimeria tenella SWP1 is an intrinsically disordered protein with the tyrosine residues concentrated in a specific region of the protein, located immediately following the region of intrinsic disorder.[SWP1] (Mus musculus) PubMed

 17593.

Four independent approaches were undertaken and demonstrated that the primary AmrZ form in solution is tetrameric.[AmrZ] (Mus musculus) PubMed

 17594.

GLT1 modulations do not significantly influence the cellular physiology, whereas the nitrogen source does.[GLT1]. (Mus musculus) PubMed

 17595.

Thermotoga maritima FliM and FliN form a 1:3 complex structurally equivalent to Spa33-FL/C2 , allowing us to propose a unified model for C-ring assembly by NF-T3SS and flagellar-T3SS.[FLiM]. (Mus musculus) PubMed

 17596.

This study characterizes a novel Fic domain protein that was identified from the human pathogen Clostridium difficile. The crystal structure shows that the protein adopts a classical all-helical Fic fold, which belongs to class II of Fic domain proteins characterized by an intrinsic N-terminal autoinhibitory alpha-helix. [fic family protein] (Mus musculus) PubMed

 17597.

GlnR regulates carbon metabolism in Streptomyces coelicolor.GlnR and Agl3R co-regulate the transcription of the agl3 operon through binding to different DNA sequences in the promoter. [Glnr] [agl3r] (Mus musculus) PubMed

 17598.

Five crystal structures of DDL from Yersinia pestis D-alanine-D-alanine ligase (DDL) were determined at 1.7-2.5 A resolution: apo, AMP-bound, ADP-bound, adenosine 5'-(beta,gamma-imido)triphosphate-bound, and D-alanyl-D-alanine- and ADP-bound structures. [D-alanine-D-alanine ligase ] (Mus musculus) PubMed

 17599.

The structure of PyrR-5-fluorouracil complex and the localization of 13 spontaneous mutational sites of PyrR obtained from 5-fluorouracil PyrR mutants.[PyrR] (Mus musculus) PubMed

 17600.

the collagen-like regions of both B. anthracis and B. cereus are similarly substituted by short O-glycans that bear the species-specific deoxyhexose residues anthrose and the newly observed cereose, respectively. Second we have discovered that the C-terminal globular domains of BclA from both species are substituted by polysaccharide-like O-linked glycans whose structures are also species-specific. (Mus musculus) PubMed

 17601.

PpNCS1B move nucleobase compounds with different efficiencies. The broad nucleobase transport profile of PpNCS1A and 1B differs from the recently-characterized Viridiplantae NCS1 in breadth, revealing a flexibility in solute interactions with NCS1 across plant evolution (Mus musculus) PubMed

 17602.

The acetylation patterns were remarkably different between two species in which the highest acetylation levels were found at H3K9 and H3K27 in wild beet and sugar beet respectively. (Mus musculus) PubMed

 17603.

UGT85B1 is essential for formation of dhurrin in sorghum.[UGT85B1] (Mus musculus) PubMed

 17604.

We found that strong depletion for RNase J led to a massive increase in the steady-state levels of non-rRNAs. mRNAs and RNAs antisense to open reading frames were most affected with over 80% increased more than 2-fold (Mus musculus) PubMed

 17605.

BolSGT1a and BolSGT1b genes are strongly associated with co-regulators during stress conditions.However, the BolSGT1 gene did not show any strong association. BolSGT1 might be a stress resistance-related gene that functions without a co-regulator. [SGT1a; SGT1b; SGT1] (Mus musculus) PubMed

 17606.

the molecular basis of the specific localizations of short-tailed Myo1A, Myo1E, and Myo1F, is reported.[Myo1A, Myo1E, Myo1F] (Mus musculus) PubMed

 17607.

These results demonstrate that the GM rice with cry2A* gene is as safe for food as conventional non-GM rice. (Mus musculus) PubMed

 17608.

MKK3 gene is mapped to chromosome 4a and plays role in seed dormancy.[MKK3] (Mus musculus) PubMed

 17609.

ZmbZIP91 acts as a core regulatory factor in starch synthesis by binding to ACTCAT elements in the promoters of starch synthesis genes.[ZmbZIP91] (Mus musculus) PubMed

 17610.

the impact of the knot on the landscape, the origin of the bistable nature of the knotted protein, is reported.[MTase] (Mus musculus) PubMed

 17611.

the dynamic architecture of prokaryotic cell membranes is controlled by the MreB cytoskeleton and regulates the mobility of transmembrane proteins.[MreB] (Mus musculus) PubMed

 17612.

SDG708-knockdown rice mutants displayed a late-flowering phenotype under both long-day and short-day conditions.[SDG708] (Mus musculus) PubMed

 17613.

Study shows that in GAS, the pefCD genes encode a multi-drug efflux system that allows the bacterium to circumvent the challenges imposed by labile heme. [pefC & pefD] (Mus musculus) PubMed

 17614.

VP4 initiates the assembly at early stage of infectious bursal disease virus infection, and gradually assembles into larger size of fibrils within the cytoplasm and nucleus. [Vp4] (Mus musculus) PubMed

 17615.

The detailed molecular and topological analyses of LjGCR1 expression patterns that are presented suggest a possible involvement in the early steps of nodule organogenesis. (Mus musculus) PubMed

 17616.

OsBBX14 regulates heading date differently under long-day (LD) and short-day (SD) conditions. [OsBBX14] (Mus musculus) PubMed

 17617.

These data support the functional divergence of GhCFE5 homoeologs in the actin cytoskeleton structure and cell elongation.[GhCFE5] (Mus musculus) PubMed

 17618.

This study provides a reliable theoretical basis for understanding the structure and catalytic mechanism of the Mycobacteria KSDD enzyme [ 3-ketosteroid-Delta(1)-dehydrogenase] (Mus musculus) PubMed

 17619.

Data demonstrate roles for HrcU and HrpP in regulating T3S and represent the first attempt in understanding type III secretion system heirarchy in E. amylovora. [HrcU and HrpP ] (Mus musculus) PubMed

 17620.

two novel bv1 maize mutants, were characterized.[Bv1] (Mus musculus) PubMed

 17621.

OsWOX3A is a gibberellic acid (GA)-responsive gene and functions in the negative feedback regulation of the GA biosynthetic pathway. (Mus musculus) PubMed

 17622.

BcStr2 plays a critical role in the regulation of various cellular processes in B. cinerea.[BcStr2] (Mus musculus) PubMed

 17623.

the expression of Dclcyb1 induces a positive feedback affecting the expression of isoprenoid gene precursors and genes involved in carotenoid, gibberellin and chlorophyll pathways.[Dclcyb1] (Mus musculus) PubMed

 17624.

components of the large latent TGFss complex were identified as novel targets of cathepsin K at neutral pH.[Tgfb] (Mus musculus) PubMed

 17625.

The apoptosis of breast cancer cells by hemagglutinin protease is is PAR-1 mediated and activates both the NFkappaB and MAP kinase signaling pathways (Hemagglutinin protease). (Mus musculus) PubMed

 17626.

Deletion of kynB resulted in reduced 2-alkyl-4-quinolone production, increased biofilm formation, decreased swarming and increased tolerance to ciprofloxacin.[kynB] (Mus musculus) PubMed

 17627.

Overexpression of SbMyb60 is associated with activation of monolignol biosynthesis in sorghum. (Mus musculus) PubMed

 17628.

the OsMSH4/5 heterodimer plays a key role in regulation of crossover formation during rice meiosis by interaction with the RPA complex.[OsMSH4] (Mus musculus) PubMed

 17629.

pore formation in red blood cells by the MACPF/CDC pneumolysin from Streptococcus pneumonia [pIY] (Mus musculus) PubMed

 17630.

These results indicate that translation attenuation mediated by the phosphorylation of eIF2alpha on threonine 169 is not necessary for the cell cycle arrest associated with differentiation processes from proliferating bloodstream form cells into arrested stumpy forms in mice and into procyclic forms in vitro and in tsetse flies. [eIF2alpha] (Mus musculus) PubMed

 17631.

Although the genes responsible for the Spc mutation were not definitively identified, our results further the current understanding of the complex mechanism underlying the multiple morphological defects in Spc mutants (Mus musculus) PubMed

 17632.

Results reveal a previously unknown method of processing non-stem-loop CRISPR RNA by Cas6 showing a dual site binding structure and a cleavage site conformation poised for phosphodiester bond breakage. [cas6] (Mus musculus) PubMed

 17633.

The presence of a Y93H variant in the nonstructural 5A region was associated with higher HCV RNA levels and TT genotype at rs8099917 of IL28B. (Mus musculus) PubMed

 17634.

canarypox virus resolvase is dimer of RNase H superfamily domains related to Escherichia coli RuvC, with an active site lined by highly conserved acidic residues that bind metal ions. There are several intriguing structural differences between resolvase and RuvC, and a model of the CPV resolvase.Holliday junction complex provides insights (Resolvase). (Mus musculus) PubMed

 17635.

the metabolic adjustment in the rice (Oryza sativa) mitochondrial Fe transporter knockdown mutant (mit-2) was analysed. [mit-2] (Mus musculus) PubMed

 17636.

BSH1 functions mainly in secondary cell wall formation, and probably in wax biosynthesis in an unidentified mechanism.[BSH1] (Mus musculus) PubMed

 17637.

PDH45 is involved in the regulation of Na(+) level, reactive oxygen species production, [Ca(2+)]cyt homeostasis, cell viability and cation transporters in roots.[PHD45] (Mus musculus) PubMed

 17638.

Phosphoenolpyruvate carboxylase (essential for the synthesis of malate and citrate) was present in the same cells and at the same time as PEPCK and NADP-malic enzyme (both utilised in the dissimilation of malate and citrate). (Mus musculus) PubMed

 17639.

Continuum electrostatic calculations show that, as expected, nonspecific electrostatic interactions between BtPI-PLC and membranes vary as a function of the fraction of anionic lipids present in the bilayers.[BtPI-PLC] (Mus musculus) PubMed

 17640.

All-atom molecular dynamics simulations suggest a dynamic equilibrium between the protonation states of the two aspartic acids and that the protonation state affects hydration in the substrate binding cavity and lipid intrusion in the cleft between the N- and C-lobes.[MATE] (Mus musculus) PubMed

 17641.

Results show three paralogous TF55 subunits, alpha, beta, and gamma that form a series of different complexes depending on the temperature. The larger octadecameric beta complexes cater for substrates under heat stress, whereas smaller hexadecameric alphabeta complexes prevail under normal conditions. The cold-shock complex contains all three subunits, consistent with greater substrate specificity. [TF55A, TF55B, TF55G] (Mus musculus) PubMed

 17642.

strong interactions are observed between cholesterol and residues in the amphipathic helix of M2 protein, accounting for cholesterol binding adjacent to a native palmitoylation site and near to an interhelix crevice that is typical of cholesterol binding sites.[M2 protein] (Mus musculus) PubMed

 17643.

This collection of calculations provides for the first time, a detailed picture of the proton transport mechanism in the central region of ClC-ec1 at a molecular level.[ClC-ec1] (Mus musculus) PubMed

 17644.

unfolding is completely reversible for HiGlpG but only partially reversible for PsAarA.[HiGlpG] (Mus musculus) PubMed

 17645.

Results show the crystal structure of SpaC protein belonging to the space group P21212 and containing two molecules in the asymmetric unit. Presence of conserved metal ion-dependent adhesion site containing von Willebrand factor type A domain suggests its likely role in the function of SpaC. [SpaC] (Mus musculus) PubMed

 17646.

unfolding is completely reversible for HiGlpG but only partially reversible for PsAarA.[PsAarA] (Mus musculus) PubMed

 17647.

Expression of wheat RSL4 gene was correlated with root hair length variation. [RSL4] (Mus musculus) PubMed

 17648.

The Aspergillus niger acetyl xylan esterase AnAXE1 was expressed in Arabidopsis under the control of either the constitutively expressed 35S CAMV promoter or a woody-tissue-specific GT43B aspen promoter, and the protein was targeted to the apoplast by its native signal peptide.[AnAXE1] (Mus musculus) PubMed

 17649.

ATE protein abundance is spatially and temporally regulated in P. patens by hormones and light and is highly abundant in meristematic cells.[ATE] (Mus musculus) PubMed

 17650.

The authors propose a model in which sigmaI can be induced in response to heat shock, whilst, independently, sigmaI is produced under non-heat-shock, toxin-inducing conditions to indirectly regulate virulence gene expression.[sigmaI] (Mus musculus) PubMed

 17651.

Ribosome dimerization followed the induction of hpf in wild-type cells, but the dimerization was impaired in cells harbouring a deletion in the hpf gene.[hpf] (Mus musculus) PubMed

 17652.

Constructed was a knockout mutant of nitrate reductase, encoded by narB, in Synechococcus sp. PCC 7002. As expected, DeltanarB was able to take up intracellular nitrate but was unable to reduce it to nitrite or ammonia, and was unable to grow photoautotrophically on nitrate. [nitrate reductase] (Mus musculus) PubMed

 17653.

This study demonstrated that katE1 encodes the chief functional catalase for detoxifying extrinsic H2O2 during logarithmic growth, while the katE2 and ahpC genes may play an alternate or compensatory role in the DeltakatE1 strain.[katE1, katE2] (Mus musculus) PubMed

 17654.

Here, a combination of protein engineering, biophysical characterization, single molecule force spectroscopy and molecular dynamics simulations directly investigates the role of salt bridges in the mechanical stability of the cold shock protein from the mesophilic organism Bacillus subtilis. [cold shock protein] (Mus musculus) PubMed

 17655.

Here a combination of protein engineering, biophysical characterisation, single molecule force spectroscopy and molecular dynamics simulations directly investigates the role of salt bridges in the mechanical stability of the cold shock proteins from the hyperthermophilic organism Thermotoga maritima. [cold shock protein] (Mus musculus) PubMed

 17656.

the specific mutation in CPB1/D11 influenced development of panicle architecture and seed size.[CPB1/D11] (Mus musculus) PubMed

 17657.

Dnj1 contributes to the establishment of a compatible interaction with the host.[Dnj1] (Mus musculus) PubMed

 17658.

study observed that N. meningitidis, via the conserved surface protein NhhA, skewed monocyte differentiation into macrophages with a CD200R(hi) phenotype. [NhhA] (Mus musculus) PubMed

 17659.

dimeric ZinT structure unravelled extra zinc binding sites that support its role in metal loading and/or transport.[ZinT] (Mus musculus) PubMed

 17660.

Study determined the structure of the CYP107W1- oligomycin A bound complex and characterized the role of the Trp178 residue and show that hydrophobic interactions at Trp178 residue in the active site played a key role to assist in the proper binding of the large macrolide substrate for regioselective hydroxylation. [CYP107W1] (Mus musculus) PubMed

 17661.

Investigated the interaction between 14-3-3 and the host and correlated the functions of P. brasiliensis 14-3-3 with cellular features, such as morphological characteristics and virulence, that are important for pathogenesis. [14-3-3]. (Mus musculus) PubMed

 17662.

StAN1,StMYBA1, and StMYB113 are well expressed, even in the absence of pigmentation.[StAN1, StMYBA1, StMYB113] (Mus musculus) PubMed

 17663.

VrDREB2A functions as an important transcriptional activator and may help increase the abiotic stress tolerance of the mung bean plant. [VrDREB2A] (Mus musculus) PubMed

 17664.

This study provides the first evidence of both the relevance of the ptsP gene in bacteriocin production and functional characterization of a pyocin S in P. fluorescens SF39a.[ptsP] (Mus musculus) PubMed

 17665.

Compared with wild-type plants, pgl exhibits a lower Chl content with a reduced and disorderly thylakoid ultrastructure, which decreases the photosynthesis rate and results in reduced grain yield and quality. [PGL] (Mus musculus) PubMed

 17666.

The Chlamydomonas genome encodes presumed plant orthologues of a chloroplast lipid transporter consisting of TGD (TRIGALACTOSYLDIACYLGLYCEROL) proteins that are required for ER-to-chloroplast lipid trafficking in plants. [TGD2] (Mus musculus) PubMed

 17667.

PtSHR2B appears to function in the phellogen and therefore in the regulation of phellem and periderm formation, possibly acting through modulation of cytokinin homeostasis.[PtSHR2B] (Mus musculus) PubMed

 17668.

The cdgA gene encoding diguanylate cyclase A (CdgA) is involved in biofilm formation and exopolysaccharide (EPS) production in Azospirillum brasilense Sp7.[cdgA] (Mus musculus) PubMed

 17669.

These results suggest that CHU_1276 plays an essential role in cellulose utilization, probably by coordinating the extracellular hydrolysis of cellulose substrate with the intracellular uptake of the hydrolysis product in Cytophaga hutchinsonii. (Mus musculus) PubMed

 17670.

The deletion of depR1 led to a reduction in dptEp activity and the cessation of daptomycin production. The DeltadepR1 mutant produced less red pigment and failed to sporulate on R5 medium. This suggests that DepR1 plays a positive role in the control of morphological differentiation.[depR1] (Mus musculus) PubMed

 17671.

HvSec14p plays essential roles in the biogenesis of membranes in expanding cells and in their preservation under osmotic stress conditions.[Sec14p] (Mus musculus) PubMed

 17672.

W959 of beta-galactosidases is critical for the synthesis of beta-3'-galactosyl-lactose. [beta-galactosidases ] (Mus musculus) PubMed

 17673.

The authors show that MsaB activates the cap operon by binding directly to a 10 bp repeat in the promoter region.[MsaB] (Mus musculus) PubMed

 17674.

Molecular simulation studies with the structure of Trypanosoma cruzi G6PDH revealed that Epiandrosterone binds in a pocket close to the G6P binding-site and protrudes into the active site blocking the interaction between substrates and hence catalysis (Mus musculus) PubMed

 17675.

crystal structure of proteolytically cleaved Ebola virus GP to a resolution of 3.3 A.; studies indicate that binding of GP to its endosomal receptor Niemann-Pick C1 occurs in two distinct stages (Mus musculus) PubMed

 17676.

UXS3 regulates the conversion of non-cellulosic polysaccharides and modulates their composition in plant cell walls. (Mus musculus) PubMed

 17677.

Data show that hrpB is involved in adherence of Xanthomonas citri subsp. citri to different surfaces and is been implicated in the regulation of type IV pili in Xanthomonas. [hrpB] (Mus musculus) PubMed

 17678.

results indicate that CP91 is a central centrosomal core component required for centrosomal integrity, proper centrosome biogenesis and, independently, for abscission during cytokinesis [CP91] (Mus musculus) PubMed

 17679.

This study provides the first evidence that protease m1 zinc metalloprotease may play a role in the regulation of DM resistance in Cx. pipiens pallens.[protease m1] (Mus musculus) PubMed

 17680.

The crystal structure of the tandem-PAS sensing domain of Campylobacter jejuni chemoreceptor Tlp1 suggests indirect mechanism of ligand recognition. [Tlp1] (Mus musculus) PubMed

 17681.

Study reveals an important phenomenon in which the VP1 S154D mutation increases the replication level of type Asia1 FMDV in host cells and enhances the pathogenicity in host pigs. [VP1] (Mus musculus) PubMed

 17682.

Abnormal expression of miR-127, miR-21 and miR-16 in placentas of deceased sheep, through dysregulation of target genes, may result in developmental deficiencies of transgenic cloned sheep.[MIR16] (Mus musculus) PubMed

 17683.

Study describe crystal structures of MAP_1272c and MAP_1204 showing that MAP_1272c does not have a functional catalytic core for peptidoglycan hydrolysis. While the NlpC/P60 catalytic triad is present in MAP_1204, changing the catalytic cysteine-155 residue to a serine significantly diminished catalytic activity, but did not affect binding to peptidoglycan. [MAP_1272c & MAP_1204] (Mus musculus) PubMed

 17684.

VviMYB80 may play an important role in stamen development and that expression of VviMYB80 driven by the 35S promoter in tobacco induces male sterility.[VviMYB80] (Mus musculus) PubMed

 17685.

Two uncharacterized nicotinamide adenine dinucleotide (NADH) oxidases (named as LpNox1, LpNox2) from Lactobacillus pentosus ATCC 8041 were cloned and overexpressed in Escherichia coli BL21 (DE3). The sequence analysis revealed that the two enzymes are water-forming Noxs with 64 % and 52 % identity to LbNox from Lactobacillus brevis DSM 20054. (Mus musculus) PubMed

 17686.

CsNIP2;1 might be involved in multiple steps of urea-based nitrogen nutrition.[CsNIP2;1] (Mus musculus) PubMed

 17687.

UGT71K3 plays role in both acylphloroglucinol glucoside and anthocyanin biosynthesis.[UGT71K3] (Mus musculus) PubMed

 17688.

findings provide the first evidence for a direct role of CPAR2_404800 in C. parapsilosis adhesion to host surfaces and demonstrate its contribution to the pathogenesis of murine urinary candidiasis [CPAR2_40] (Mus musculus) PubMed

 17689.

Two novel esterases from the anaerobe Clostridium botulinum ATCC 3502 (Cbotu_EstA and Cbotu_EstB) were expressed in Escherichia coli BL21-Gold(DE3) and were found to hydrolyze the polyester poly(butylene adipate-co-butylene terephthalate). [EstA, EstB] (Mus musculus) PubMed

 17690.

These data showed that Mycobacterium tuberculosis ESAT-6 and ESAT-6/CFP-10 fusion proteins could induce adhesion of macrophages to fibronectin through alpha4beta1 integrin.[ESAT-6] (Mus musculus) PubMed

 17691.

These data provide valuable information for the first time regarding meningococcal Opa PV. The presence of Opa PV in meningococcal populations and high expression of Opa among invasive strains likely indicates the importance of this protein in bacterial colonization in the human nasopharynx (Mus musculus) PubMed

 17692.

Results suggest that OsPLDalpha1 plays a key role in transducing cold signaling in rice by producing phosphatidic acid (PA) and regulating OsDREB1s' expression by OsMPK6, OsSIZ1, and possibly other PA-binding proteins. (Mus musculus) PubMed

 17693.

Our study demonstrates for the first time a conserved putative RNA Pol I transcription factor TIF-IA in E. histolytica. (Mus musculus) PubMed

 17694.

Notably, Shewanella piezotolerans WP3Deltahns exhibited higher expression levels of lateral flagellar genes than wild-type WP3 and showed enhanced swarming motility and lateral flagellar production compared to those of WP3.[hns] (Mus musculus) PubMed

 17695.

Data show that Mediator subunit 25 (TaMED25) and ETHYLENE INSENSITIVE3-LIKE1 (TaEIL1) synergistically modulate disease resistance to Blumeria graminis [MED25 and EIL1] (Mus musculus) PubMed

 17696.

Loss-of-function and gain-of-function experiments indicated that OmNOD1 is involved in the expression of pro-inflammatory cytokines. Silencing of OmNOD1 in RTH-149 cells treated with iE-DAP decreased the expression of IL-1beta, IL-6, IL-8 and TNF-alpha.[NOD1] (Mus musculus) PubMed

 17697.

The authors show that the UDP-glucose pyrophosphorylase ExoN activity is modulated by SMc02309-mediated tyrosine dephosphorylation.[ExoN, SMc02309] (Mus musculus) PubMed

 17698.

PpeGID1c serves a primary role in vegetative growth and elongation, whereas GID1b probably functions to regulate gibberellic acid perception in reproductive organs. (Mus musculus) PubMed

 17699.

A new laccase from Lactobacillus plantarum J16 CECT 8944 catalyzing biogenic amines degradation has been characterized. [Laccase] (Mus musculus) PubMed

 17700.

Mutation in genes srtA and mucBP leads to a significant decrease in LMD-9 adhesion capacity to Caco-2 TC7 cells.[srtA and mucBP] (Mus musculus) PubMed

 17701.

Chast can be a potential target to prevent cardiac remodeling and highlight a general role of long noncoding RNAsin heart diseases.[Chast lnc RNA] (Mus musculus) PubMed

 17702.

zFEL appears to be a maternal immune-relevant molecule capable of defending the developing embryos/larvae from pathogenic attacks.[FEL] (Mus musculus) PubMed

 17703.

comparative analysis indicated that the strategies for endoderm, and dorsal specification, involving vegt and mix1, have been evolutionary conserved in frogs[Mix1 and VegT] (Mus musculus) PubMed

 17704.

The aim of this study is to reveal if the crosstalk between matriptase activators and intestinal epithelial monolayers can lead to perturbations in physiological redox regulation in vitro. (Mus musculus) PubMed

 17705.

The authors report the identification in Brucella abortus of a novel adhesin (BigA) that harbours a bacterial immunoglobulin-like domain and demonstrate that this protein is involved in the adhesion to polarized epithelial cells such as the Caco-2 and Madin-Darby canine kidney models targeting the bacteria to the cell-cell interaction membrane.[BigA] (Mus musculus) PubMed

 17706.

Therefore, the protein encoded by orf19.4531 is involved in azole sensitivity and we name it as ROA1, the regulator of azole sensitivity 1 gene.[ROA1] (Mus musculus) PubMed

 17707.

MaNAC5 cooperates with MaWRKY1 and MaWRKY2 to regulate the expression of a specific set of pathogenesis-related genes in the disease response.[MaNAC5, MaWRKY1, MaWRKY2] (Mus musculus) PubMed

 17708.

Microspore-derived embryo (MDE) formation and plantlet regeneration seems to be correlated with both BnSERK1 and BnSERK2 expression. [SERK1, SERK2] (Mus musculus) PubMed

 17709.

Colistin resistance caused by inactivation of the MgrB regulator is not associated with decreased virulence of sequence type 258 KPC carbapenemase-producing Klebsiella pneumoniae. [MgrB] (Mus musculus) PubMed

 17710.

This study determined the structures of the hepatitis C virus helicase (NS3h) in complex with the transition state ATP mimic ADP.AlF4 (-) and compared them with the previous nucleic acid-associated ternary complexes. The results suggested that nucleic acid binding promotes a structural change of the spring helix at the transition state, optimizing the interaction network centered on the nucleophilic water. [NS3 Helicase] (Mus musculus) PubMed

 17711.

Data show that TIMING OF CAB EXPRESSION-A1 (TaTOC-A1), TaTOC-B1, and TaTOC-D1 proteins are targets of microRNA tae-miR408: [TaTOC-A1), TaTOC-B1, TaTOC-D1, and tae-mir408] (Mus musculus) PubMed

 17712.

Study describes molecular cloning and biochemical characterization of purified Lcp protein and showed that all the studied Lcp proteins can differ in some spectroscopic features and/or in spatial arrangements of their metal ions/cofactors and indicate the presence of two or even more subgroups of Lcp proteins. [Lcp] (Mus musculus) PubMed

 17713.

This method reproducibly yielded 3 mg of streptopain from 50 mL of expression culture at 95% purity, with an activity of 5306 +/- 315 U/mg, and no remaining affinity tags or artifacts from recombinant expression (Mus musculus) PubMed

 17714.

According to pbp4 gene sequencing, this study suggests that a specific amino acid substitution in pbp4 gene found in all penicillin-resistant, ampicillin-susceptible Enterococcus faecalis (PRASEF) analyzed is associated with penicillin resistance. (Mus musculus) PubMed

 17715.

coleoptile length has been increased in transgenic lines with down-regulated glucan, water dikinase independently of grain size increases.[ glucan, water dikinase] (Mus musculus) PubMed

 17716.

This study showed that proanthocyanidins suppress the secretion of Salmonella pathogenicity island 1 (Spi1) virulence proteins in Salmonella typhimurium SJW1103.[Spi1] (Mus musculus) PubMed

 17717.

Data suggest that, in this species, CSP1 and CSP2 exhibit higher affinities for pheromones and volatile floral chemicals than CSP4; antennae exhibit highest expression of CSP1 and CSP2. [CSP1] (Mus musculus) PubMed

 17718.

Novel 4-methyl-2-oxopentanoate reductase (MOA reductase A, MorA) involved in synthesis of the Japanese sake flavor, ethyl leucate, has been characterized. [MorA] (Mus musculus) PubMed

 17719.

PCR [for FliC-d Gene of Salmonella Typhi ] has been found to be a reliable method for diagnosing various infectious diseases.In cases of typhoid, it can be very useful when the organism load is low as well as for detecting non- viable pathogens when the patient is taking antibiotics. (Mus musculus) PubMed

 17720.

two genes encoding endopolygalacturonase (endoPG) in the F-M locus, designated PpendoPGF and PpendoPGM, are associated with the melting flesh and stone adhesion traits.[PpendoPGF, PpendoPGM] (Mus musculus) PubMed

 17721.

type III effectors AvrRpm1 and AvrRpt2 promote bacterial virulence by targeting a COI1-dependent signaling pathway. [AvrRpm1 and AvrRpt2] (Mus musculus) PubMed

 17722.

These results suggest that MorC influences fimbrial secretion and microcolony formation in Aggregatibacter actinomycetemcomitans.[MorC] (Mus musculus) PubMed

 17723.

Data show that HTLV-1 basic leucine zipper (bZIP) factor (HBZ) represses p53 activity by direct inhibition of the histone acetyltransferase (HAT) activity of p300/CBP and the HAT activity of HBO1: [HBZ] (Mus musculus) PubMed

 17724.

OsVIL1 forms a PRC2-like complex to induce flowering by suppressing OsLF under short day but delay flowering by elevating Ghd7 expression under long day.OsVIL1, OsLF, Ghd7] (Mus musculus) PubMed

 17725.

Helicobacter pylori is dependent on CagA translocation to induce intracellular osteopontin expression in gastric epithelial cells, and may promote gastric carcinogenesis via increased beta-catenin accumulation and interleukin-8 secretion. (Mus musculus) PubMed

 17726.

roles of a conserved tyrosine residue in a Mip-like peptidyl-prolyl cis-trans isomerase [FKBP22] (Mus musculus) PubMed

 17727.

crystal structure of Escherichia coli CsdE [CsdE] (Mus musculus) PubMed

 17728.

The crystal structure at 2.0 A resolution of a thermostable GRHPR from Pyrococcus furiosus as a ternary complex in the presence of D-glycerate and NADPH has been determined. (Mus musculus) PubMed

 17729.

The crystal structure at 2.0 A resolution of a thermostable GRHPR from Pyrococcus horikoshii as a ternary complex in the presence of D-glycerate and NADPH has been determined. (Mus musculus) PubMed

 17730.

present study shows that the low prevalence polymorphism mutations of PfATPase6 and limited mutations of K13-propeller, potentially associated with ART resistance, are observed on Bioko Island, Equatorial Guinea[K13-propeller, ATPase6] (Mus musculus) PubMed

 17731.

Result indicate Mga2 as a transcriptional regulator of triacylglycerol and glycerophospholipid homeostasis: [Mga2] (Mus musculus) PubMed

 17732.

PpACL1 and PpACL2 are not true ACS genes as those found in higher plants.[PpACL1, PpACL2] (Mus musculus) PubMed

 17733.

Clone and express of GRA7 protein of T. gondii and evaluate its potential for immunodiagnosis of toxoplasmosis in cancer patients. (Mus musculus) PubMed

 17734.

The conserved protein BOP1 is essential for viability. (Mus musculus) PubMed

 17735.

the specific functions of two novel MYB transcription factors, designated as PbMYB10b and PbMYB9, were further verified by both overexpression and RNA interference transient assays.[PbMYB10b, PbMYB9] (Mus musculus) PubMed

 17736.

Map-based cloning has revealed that RLS2 encodes OsEXO70A1, which is one of the 47 members of EXO70s in rice.[OsEXO70A1] (Mus musculus) PubMed

 17737.

Methyl jasmonate-induced accumulation of cytokinins was due to inhibition of both cytokinin oxidase (CKX) (cytokinin oxidase/dehydrogenase, EC 1.5.99.12) gene expression and activity of this enzyme.[cytokinin oxidase] (Mus musculus) PubMed

 17738.

SRL2 plays an important role in regulating leaf development, particularly during sclerenchymatous cell differentiation.[SRL2] (Mus musculus) PubMed

 17739.

Subcellular localization indicated that OsPMEI8 is targeted to the middle lamella and OsPMEI12 is localized in the plasma membrane and nucleus. (Mus musculus) PubMed

 17740.

Salmonella Typhimurium type III secreted effector SipC significantly contributes to PERP redistribution to the apical membrane surface. [SipC] (Mus musculus) PubMed

 17741.

GhMYB108 acts as a positive regulator in defense against V. dahliae infection by interacting with GhCML11. (Mus musculus) PubMed

 17742.

Strongylocentrotus purpuratus Pou4f1/2 and mouse Pou4f2 share conserved components of a gene network for photosensory development and they maintain their conserved intrinsic functions despite vast morphological differences in mouse and sea urchin photosensory structures.[Pou4f1/2] (Mus musculus) PubMed

 17743.

Study solved the AraC-triacetic acid lactone ligand-binding domain structure by X-ray crystallography to gain further insights into the sequence-to function relationships. (Mus musculus) PubMed

 17744.

Yr36 gene affects the reactive oxygen species accumulation and cell death of the wheat infected with pathogen Puccinia striiformis f. sp. tritici. [YR36] (Mus musculus) PubMed

 17745.

results support the low temperature biosynthetic role of OsPho1 in rice endosperm and indicate that its L80 region is unlikely to have a direct enzymatic role but provides stability of the enzyme under heat stress. (Mus musculus) PubMed

 17746.

Data reveal low frequency conformational motions in the active site of NP_344798.1. [NP_344798.1] (Mus musculus) PubMed

 17747.

The protein encoded by BmVMP25 is expressed exclusively in the follicle cells from stages -6 to +1, accumulates on the surface of oocyte from where it decreases and disappears. This confirms that BmVMP25 is not insect VMP, and was renamed BmECM25. (Mus musculus) PubMed

 17748.

Pic is a virulence factor associated with adherence, colonization and evasion from the innate immune system.[pic] (Mus musculus) PubMed

 17749.

Pdr11 plays an essential role in fluconazole susceptibility in C. gattii. [pdr11] (Mus musculus) PubMed

 17750.

Analysis of 22 nonredundant mutants showed that, in contrast to their in vitro-selected counterparts, only 3 of the clinical isolates (13.6%) harbored a disrupted mexS gene, which codes for the oxidoreductase MexS. [MexS] (Mus musculus) PubMed

 17751.

The role of nsP2 protease in recognition of small peptide substrates [nsP2 protease] (Mus musculus) PubMed

 17752.

The role of Cas8 in type I CRISPR interference [cas8] (Mus musculus) PubMed

 17753.

A family 1 cellulose-binding domain (CBD 1) encoding gene from the potato late blight pathogen P. infestans was used to develop transgenic Bintje potato plants.[CBD1] (Mus musculus) PubMed

 17754.

different levels of heterogeneity in LPS environments on the structure and dynamics of OmpF using all-atom molecular dynamics simulations (Mus musculus) PubMed

 17755.

AlkB has been reported to repair highly susceptible substrates, such as 1-methyladenine and 3-methylcytosine, more efficiently in ss-DNA than in ds-DNA. This study tested the repair of weaker AlkB substrates 1-methylguanine and 3-methylthymine and found that AlkB prefers to repair them in ds-DNA. [AlkB] (Mus musculus) PubMed

 17756.

Both YpdB and YpdB-D53E bound as monomers to the tandem-repeat sequences in the promoter, with YpdB-D53E displaying a higher maximal binding rate than YpdB. (Mus musculus) PubMed

 17757.

Low melatonin production by suppression of either serotonin N-acetyltransferase or N-acetylserotonin methyltransferase in rice causes seedling growth retardation with yield penalty, abiotic stress susceptibility, and enhanced coleoptile growth under anoxic conditions. (Mus musculus) PubMed

 17758.

Q388A3, conserved in the related kinetoplastid parasites, is a 1634-residue protein containing a PDZ domain at its C-terminus. [Q388A3] (Mus musculus) PubMed

 17759.

Results show the molecular cloning and characterization Rhamnogalacturonan Lyase which displays maximum activity against rhamnogalacturonan I in the presence of Ca(2+) ions. [RGL] (Mus musculus) PubMed

 17760.

CrDGTT1, CrDGTT2 and CrDGTT3 possess distinct specificities toward acyl CoAs and diacylglycerols, and may work in concert spatially and temporally to synthesize diverse TAG species in C. reinhardtii. [CrDGTT1, CrDGTT2, CrDGTT3] (Mus musculus) PubMed

 17761.

Genomic characterization of Enterobacter cloacae isolates from China that coproduce KPC-3 and NDM-1 carbapenemases has been presented. [blakpc-3] (Mus musculus) PubMed

 17762.

Psoriasis susceptibility-related RNA Gene Induced by Stress (PRINS) is significantly up regulated in hypoxic conditions and had specific interaction with RANTES as confirmed through reporter assay. [PRINS] (Mus musculus) PubMed

 17763.

BmATG5 and BmATG6 mediate apoptosis following autophagy induced by 20-hydroxyecdysone or starvation in Bombyx Bm-12 cells.[BmATG5, BmATG6] (Mus musculus) PubMed

 17764.

RpoS positively regulates the global stress response to acid or alkaline stresses, oxidative stress, hyperosmolarity, heat shock and carbon starvation, in addition to proteolytic and chitinolytic activities. (Mus musculus) PubMed

 17765.

ORF79 influences the pollen fertility and mitochondrial ORF79 levels determine pollen abortion in cytoplasmic male sterile rice. [orf79] (Mus musculus) PubMed

 17766.

Transgenic lines with the TaRAP2.1Lmut transgene had an enhanced ability to survive frost and drought.[taRAP2.1l] (Mus musculus) PubMed

 17767.

OsAIR1 may positively regulate post-germination plant growth under stress conditions.[OsAIR1] (Mus musculus) PubMed

 17768.

A novel thermostable taurine-pyruvate transaminase from Geobacillus thermodenitrificans has been identified. [Taurine-pyruvate transaminase] (Mus musculus) PubMed

 17769.

Results identified five isoforms of diacylglycerol O-acyltransferase type 2 (DGAT-2). The accumulation of DGTT1 mRNA increases considerably under nitrogen and iron inanition when compared to the other isoforms, which indicated that each isoform participates at different levels under each stress condition. [DGTT] (Mus musculus) PubMed

 17770.

Silencing of Phytophthora sojae aspartate aminotransferase 3 (PsAAT3), an infection-inducible expression gene, reduced Phytophthora sojae pathogenicity on soybean plants and affected the growth under nitrogen-starving condition, suggesting that PsAAT3 is involved in pathogen pathogenicity and nitrogen utilisation during infection.[AAT3] (Mus musculus) PubMed

 17771.

The determination of reaction products catalyzed by the purified enzymes or mutants indicated that NdhAB catalyzed nicotine oxidation to 6-hydroxynicotine, whereas Pno oxidized 6-hydroxypseudooxynicotine to 6-hydroxy-3-succinoylsemialdehyde pyridine.[NdhA, NdhB, Pno] (Mus musculus) PubMed

 17772.

Data show that transcription of organizer-specific bone morphogenetic protein 2b(bmp2b) is directly down-regulated by Nodal and up-regulated by Wnt signal: [Nodal] (Mus musculus) PubMed

 17773.

Therefore, Helicobacter pylori might induce TGF-beta1-mediated epithelial-mesenchymal transition associated with the cagE. (Mus musculus) PubMed

 17774.

NopL interacts with MAP kinases and reveals the importance of serine-proline motifs for effector activity during symbiosis.[NopL] (Mus musculus) PubMed

 17775.

The differential regulation of DosR regulon proteins is necessary for the development of a dormant Mycobacterium tuberculosis Beijing strain B0/W148 phenotype that is less susceptible to rifampicin. (Mus musculus) PubMed

 17776.

Data show that ferredoxin/flavodoxin-NAD(+) reductase (Rnf) acts as a Na(+) pump: [Rnf] (Mus musculus) PubMed

 17777.

Results present the gene gumB, encoding an outer membrane xanthan exporter with a strong antisense transcription start sites. [gumB] (Mus musculus) PubMed

 17778.

Interactions between CagA and host proteins trigger the development of inflammatory responses and multi-step gastric cancer.[review] (Mus musculus) PubMed

 17779.

These data suggest that spiE is involved in the whcE-mediated oxidative stress response pathway of Corynebacterium glutamicum.[SpiE, WhcE] (Mus musculus) PubMed

 17780.

Transgenic rice plants expressing Lr34 showed increased resistance against multiple isolates of the hemibiotrophic pathogen Magnaporthe oryzae, the causal agent of rice blast disease. [Lr34] (Mus musculus) PubMed

 17781.

Hpsh4590 was found localized in the membrane and the periplasm of H. pylori, interacted with zinc finger protein and methionine ABC transporter ATP-binding protein, and potentially regulates DNA uptake or transfer.[Hpsh4590] (Mus musculus) PubMed

 17782.

CpxQ combats toxicity at the inner membrane by downregulating the synthesis of the periplasmic chaperone Skp. [CpxQ] (Mus musculus) PubMed

 17783.

RipAY is activated by host cytosolic thioredoxins and degrades glutathione specifically in plant cells to suppress plant immunity. [RipAY] (Mus musculus) PubMed

 17784.

Our results showed that the recombinant bacteria had the capacity to synthesize gamma-PGA. The expression product was secreted extracellularly into the fermentation broth, with a product yield of 1.74 g/L or higher. gamma-PGA samples from the fermentation broth were purified and characterized. (Mus musculus) PubMed

 17785.

High presence of H. pylori strains in milk and meat samples similar to vacA genotypes in human being suggests that milk and meat samples could be the sources of bacteria for human. (Mus musculus) PubMed

 17786.

Loss of AdeRS or AdeB significantly altered the transcriptional landscape, resulting in the changed expression of many genes, notably those associated with antimicrobial resistance and virulence interactions. [AdeR, AdeS] (Mus musculus) PubMed

 17787.

Usv101 is a master regulator of pathogenesis, regulating melanin production, capsule growth, and capsule shedding. [Usv101] (Mus musculus) PubMed

 17788.

The described is enzymatic characterization and cellular localization of PfSET7, a novel AdoMet-dependent histone H3 lysine methyltransferase in sporozoite, liver and erythrocytic stages of Plasmodium falciparum parasites. [PfSET7] (Mus musculus) PubMed

 17789.

[EsaE] that EsaE is probably an apparatus protein of Type III secretion system , which contributes to the pathogenesis of E. tarda in fish (Mus musculus) PubMed

 17790.

casein kinase 1 alpha, CK1alpha: deletion of CK1alpha may increase acute virulence of T. gondii in mice by increased expression of ROPs, activation of STAT3, and suppression of IL-12 production, which have important implications for elucidating regulation mechanism of virulence factors for T. gondii. (Mus musculus) PubMed

 17791.

The C-terminal domain of RecJ binds the C-terminal domain of SSB, which explains how RecJ and SSB work together to efficiently process broken DNA ends for homologous recombination. (Mus musculus) PubMed

 17792.

we demonstrated that PLG functions as a molecular bridge between tricellulin and streptococcal surface enolase (SEN). The wild type strain efficiently translocated across the epithelial monolayer, accompanied by cleavage of transmembrane junctional proteins. (Mus musculus) PubMed

 17793.

PfAKAL is an atypical A-kinase anchoring protein (AKAP) that shares common features with human AKAP18, such as nucleotides binding. The interaction of PfAKAL with PfPKA-R could be indirectly mediated through a join interaction with Pf14-3-3I. Therefore, PfPKA localization could not depend on PfAKAL, but rather involves other partners. (Mus musculus) PubMed

 17794.

Kat1 transposase induces DNA hairpin formation and mating type switching. [Kat1] (Mus musculus) PubMed

 17795.

syntaxin 8 (MoSyn8), a Qc-SNARE protein homolog, also plays important roles in growth, conidiation, and pathogenicity.[MoSyn8] (Mus musculus) PubMed

 17796.

These data lead to a better understanding of the important role of AQP8 in the development and pathogenesis of plant pathogens.[Aqp8] (Mus musculus) PubMed

 17797.

P19 is required for adhesion to embryonic bovine lung cell. [p19] (Mus musculus) PubMed

 17798.

Results identify Spa47 as a Shigella T3SS ATPase and suggest that its activity is linked to oligomerization, perhaps as a regulatory mechanism as seen in some related pathogens. Additionally, Spa47 catalyzed ATP hydrolysis appears to be essential for host cell invasion. [Spa47] (Mus musculus) PubMed

 17799.

TGFbeta-2 functioned specifically during fracture healing to stimulate the migration of osteoblasts as well as the differentiation of osteoblasts and osteoclasts.[Tgfb2] (Mus musculus) PubMed

 17800.

The results of our study indicate that Cynoglossus semilaevis TLR2 is a TLR2 homologue that signals probably through the MyD88-mediated pathway, and that recombinant csTLR2 interacts with a wide range of bacteria and inhibits Edwardsiella infection into host cells and dissemination in host tissues, suggesting a role of TLR2 in the antibacterial immunity of teleost and adding insight into the function of TLR2 [TLR2] (Mus musculus) PubMed

 17801.

B cell activating factor (BAFF) plays an important role in the proliferation of Nile tilapia B cells and has functional cross-reactivity among Nile tilapia and mammals; therefore, BAFF may represent a useful factor for enhancing immunological efficacy in animals [BAFF, TNFSF13B] (Mus musculus) PubMed

 17802.

Global transcription rates and chromatin changes accompanying the transformation process induced by MLL-ENL were monitored.[MlLL-ENL] (Mus musculus) PubMed

 17803.

SepG coordinates septum synthesis and chromosome organization in Streptomyces.[SepG] (Mus musculus) PubMed

 17804.

phosphorylation regulates Atg9 interaction with Atg23 and Atg27.[Atg9] (Mus musculus) PubMed

 17805.

MPODD protein has a conserved mitochondrial role that is important for myzozoans.[MPODD] (Mus musculus) PubMed

 17806.

AChE suppression inhibited shoot gravitropism in rice seedlings.[AChE] (Mus musculus) PubMed

 17807.

Medicago truncatula bHLH MtTT8 was characterized as a central component of ternary complexes that control anthocyanin and proanthocyanidin biosynthesis.[MtTT8] (Mus musculus) PubMed

 17808.

Using reverse genetics we rescued a virus containing non-stearoylated HEF, which was stable during serial passage and showed no competitive fitness defect, but the growth rate of the mutant virus was reduced by one log. Deacylation of HEF does neither affect the kinetics of its plasma membrane transport nor the protein composition of virus particles (Mus musculus) PubMed

 17809.

Results showed that both miR-29b-1 and miR-29a mRNA significantly upregulated in porcine alveolar macrophages infected with PRRSV starting around 6 hours. However, miR-29c expression was very low in PAM. [miR-29b-1, miR-29a, miR-29c] (Mus musculus) PubMed

 17810.

Study solved the crystal and small-angle X-ray scattering structure of the first three periplasmic domains of CdsD protein which shows the same fold as seen in the structures of the homologs (PrgH and YscD), but the compactness is different. The crystal packing interactions may resemble the mode of assembly of this part of CdSD in the complete 24-mer ring structure. [CdsD] (Mus musculus) PubMed

 17811.

Cleavage of DAP5 by coxsackievirus B3 2A protease facilitates viral replication and enhances apoptosis by altering translation of IRES-containing genes [2A protease] (Mus musculus) PubMed

 17812.

OsWRKY53 functions not only as a regulator of plants' investment in specific defenses, but also as a switch to initiate new defenses against other stresses.[OsWRKY53] (Mus musculus) PubMed

 17813.

SbFT1, SbFT8 and SbFT10 were identified as potential candidates for encoding florigens.[SbFT1, SbFT8, SbFT10] (Mus musculus) PubMed

 17814.

RCF3 is indispensable as a scaffold protein for the assembly of the restoration of fertility complex.[RFC3] (Mus musculus) PubMed

 17815.

The S. aureus are grown at the air-liquid interface to allow an in-depth evaluation of a simulated colonization state. Exposure to wild-type, S. aureus bacteria or conditioned media killed airway epithelial cells within 1 day, while mutant S. aureus strains lacking alpha-toxin (hla) persisted on viable cells for at least 2 days (Mus musculus) PubMed

 17816.

complex physical interaction between OsWAK proteins, is reported.[OsWAK14, OsWAK91, OsWAK92] (Mus musculus) PubMed

 17817.

EAS1 represents a functional PaO, which is involved in chlorophyll degradation and may utilize a unique mechanism for its import into the chloroplast [eas1] (Mus musculus) PubMed

 17818.

MtRBOHE-mediated reactive oxygen species production plays a crucial role in the intracellular accommodation of arbuscules.[MtRBOHE] (Mus musculus) PubMed

 17819.

CagA increased tumor suppressor genes hypermethylation via stimulating DNMT1 expression through the AKT-NFkappaB pathway. [CagA] (Mus musculus) PubMed

 17820.

These results indicate the existence of a checkpoint between the extension and septation of sporogenic hyphae that involves the ParA and ParB proteins. [ParA, ParB] (Mus musculus) PubMed

 17821.

there is a causal link between the amount of Mecp2 and the N-glycosylation of NPP-5. [NPP-5] (Mus musculus) PubMed

 17822.

interaction of C. trachomatis Ctad1 with integrin beta1 mediates EB adhesion and induces signaling processes that promote host-cell invasion. (Mus musculus) PubMed

 17823.

biological relevance of the ICP0- USP9X complex in HSV-1 infection (ICP0) (Mus musculus) PubMed

 17824.

Vat-AIEC transcription was stimulated by several chemical conditions found in the ileum environment. Finally, the screening of E. coli strains isolated from CD patients revealed a preferential vat-AIEC association with AIEC strains belonging to the B2 phylogroup (Mus musculus) PubMed

 17825.

The properties of three mutated enzymes obtained in the three-round mutation were investigated. In the conversion of glycolonitrile, the variant (Mut2) accumulated the highest concentration of glycolic acid at 10.6 g l(-1), a much higher value than the wild type (3.2 g l(-1)). (Mus musculus) PubMed

 17826.

Involvement of KtrB and KDPA proteins in the response to external pH change, high-intensity light stress and heavy metal stress [KtrB] [KDPA] (Mus musculus) PubMed

 17827.

uL11 is an important element in various aspects of 'ribosomal life'.[uL11] (Mus musculus) PubMed

 17828.

The authors show that Rqh1 plays a major role in limiting Exo1-dependent direct repeat recombination induced by replication fork stalling but only a minor role in constraining recombination induced by fork breakage.[Rqh1, Exo1] (Mus musculus) PubMed

 17829.

Cation channel TRPA1, in addition to playing a conserved role in thermoregulation and chemosensation, is required for this specialized host-selective thermotaxis in mosquitoes.[TRPA1] (Mus musculus) PubMed

 17830.

Hypothalamic CART role in the reduction in food intake mediated by 5-HT2C receptors [CART] Serotonin 5-HT2C receptor role in food intake [Serotonin 5-HT2C receptor] (Mus musculus) PubMed

 17831.

FlbC is involved in the transcriptional regulation of glucoamylase (GlaB) and acid protease (PepA).[GlaB, PepA] (Mus musculus) PubMed

 17832.

Data show the crystal structure of a fusion between BamD and the POTRA4-5 domains of BamA from Rhodothermus marinus and reveal the interaction interface which physiological relevance is validated. Residues in BamA and BamD previously shown to be important for their interaction also map to the interface. [BamA] and [BamD] (Mus musculus) PubMed

 17833.

Results show that Tse2 has structural features similar to ADP-ribosylating toxins, its active-site is consistent with an NAD-dependent activity, and forms an inactivated heterotetrameric complex with the Tsi2 anti-toxin. [Tse2] (Mus musculus) PubMed

 17834.

Results indicated that the expression of vgb and metK gene improved on epsilon-PL synthesis and biomass for S. albulus NK660, respectively. (Mus musculus) PubMed

 17835.

C9orf72 regulates immune homeostasis and an autoimmune response reminiscent of systemic lupus erythematosus (SLE) occurs in its absence. [C9orf72] (Mus musculus) PubMed

 17836.

HOX12 acts directly through EUI1 to regulate panicle exsertion in rice. [HOX12] (Mus musculus) PubMed

 17837.

the effects of loops adjacent to active region on enzymic properties of Man1312 were investigated.[mannanase] (Mus musculus) PubMed

 17838.

saturation mutagenesis of DBR1 and Gal4 show that the experimental phenotypes for over 80% of the mutations correlate well with predicted effects of mutations on protein stability and RNA binding affinity.[Gal4] (Mus musculus) PubMed

 17839.

The authors show that as [H(+)] is increased to protonate a conserved glutamate and enrich the outward-facing state, a residue ~20 A away from this glutamate, near the subunit interface, moves from buried to solvent-exposed.[CLC-ec1] (Mus musculus) PubMed

 17840.

This work reveals the genetic and functional variation of the essential core type III effectors RipG7 from R. solanacearum.[RipG7] (Mus musculus) PubMed

 17841.

The authors identified an open reading frame (Ct461, renamedlpxG) encoding a previously uncharacterized enzyme that complements the UDP-diacylglucosamine hydrolase function in E. coli and catalyzes its conversion to lipid X in vitro.[LpxG] (Mus musculus) PubMed

 17842.

this study identified CagA to be an essential bacterial factor for H. pylori-mediated suppression of host HSP expression (Mus musculus) PubMed

 17843.

VPS41 up-regulates ICL1 expression to promote survival of C. neoformans under nitrogen starvation. [ICL1, VPS41] (Mus musculus) PubMed

 17844.

RpaB and PsrR1 constitute a feed-forward loop for the regulation of photosystem I gene expression to achieve a rapid acclimation response to the damaging high-light conditions.[psrr1] [RPAB] (Mus musculus) PubMed

 17845.

OsCOL10 functions as a flowering time repressor that links Ghd7 and Ehd1 in rice.[OsCOL10] (Mus musculus) PubMed

 17846.

Its marginally stable hydrophobic interface enables a switch between a state of great rotational dynamics in the kinase mode and a more rigid conformation in the phosphatase mode in response to signal perception by the periplasmic domains.[BvgS] (Mus musculus) PubMed

 17847.

the distribution, mutation and expression of psm-mec and the relationship between this gene and biofilm formation (psm-mec) (Mus musculus) PubMed

 17848.

Polygalacturonase-inhibiting protein 4 confers resistance to bacterial leaf streak in rice.[OsPGIP4] (Mus musculus) PubMed

 17849.

These results suggested B. subtilis as an appropriate host for expression of phy168 mutants and that the strategy of creating mutants in one host and expressing them in another might be a new solution to industrial production of proteins with desired properties. (Mus musculus) PubMed

 17850.

GH3 function in P. patens WT could lie in the regulation of IAA concentrations under unfavorable environmental conditions.[GH3] (Mus musculus) PubMed

 17851.

the zrt1 deletion cells provide resistance towards Cadmium and aid in the maintenance of lipid homeostasis in yeast cells.[ZRT1] (Mus musculus) PubMed

 17852.

Results demonstrate that both ClpS1 and ClpS2 from Agrobacterium tumefaciens deliver N-end-rule substrates to ClpA and are differentially expressed during bacterial. [ClpS1] and [ClpS2] (Mus musculus) PubMed

 17853.

NagZ, a protein associated with peptidoglycan recycling, has moonlighting activity that allows it to modulate biofilm accumulation by Neisseria gonorrhoeae. [NagZ] (Mus musculus) PubMed

 17854.

the bacterial blight resistance genes, Xa3 and Xa4, and a closely linked cold-tolerance QTL were mapped to rice chromosome 11 [Xa3; Xa4] (Mus musculus) PubMed

 17855.

Smt1p: Smt1p is likely to be involved in regulation of mitochondrial translation of the ATP8/ATP6. The mechanism of this regulatory pathway is proposed to entail a displacement of the repressor from the translationally mute Smt1-ATP8/ATP6 complex by F1, thereby permitting the Atp22p activator to interact with and promote translation of the mRNA. (Mus musculus) PubMed

 17856.

These findings uncover novel hallmarks of Spinal muscular atrophy disease progression and link SMN to general male infertility.[SMN2] (Mus musculus) PubMed

 17857.

RDD1 can contribute to the increased grain productivity of rice via inducing the efficient uptake and accumulation of various nutrient ions. [RDD1] (Mus musculus) PubMed

 17858.

The Golgi-resident aspartyl protease 5 (ASP5) matures substrates at both the N- and C-terminal ends of proteins and also controls trafficking of effectors without this motif.[ASP5] (Mus musculus) PubMed

 17859.

The dimeric structure of IrmA displays similarity to those of human cytokine receptors, including the interleukin-2 receptor (IL-2R), interleukin-4 receptor (IL-4R), and interleukin-10 receptor (IL-10R) binding domains, and the authors showed that purified IrmA can bind to their cognate cytokines.[IrmA] (Mus musculus) PubMed

 17860.

ssays of heterologously expressed transglycosylases ScGas1, ScCrh1, and ScCrh2 from the yeast Saccharomyces cerevisiae, CaPhr1 and CaPhr2 from Candida albicans, and of a plant xyloglucan endotransglycosylase (XET) are demonstrated. (Mus musculus) PubMed

 17861.

These studies reveal a light-sensitive interaction between the light-oxygen-voltage and basic region leucine zipper DNA-binding domain that together with light-oxygen-voltage domain dimerization results in modulation of the DNA affinity of Au1a.[Au1a] (Mus musculus) PubMed

 17862.

PhumOR2 is a sensitive receptor of natural repellents that could be used to develop novel efficient molecules to control these insects. (Mus musculus) PubMed

 17863.

D-alanyl-D-alanine carboxypeptidase releases D-alanine from peptidoglycan (PG) precursors, thereby reducing the substrate pool for PG crosslinking (transpeptidation). (Mus musculus) PubMed

 17864.

Experimental results on Spy-Im7 interactions were used to construct a model for how this chaperone interacts with its clients. It appears that Spy binds to and releases client proteins in a regulated fashion that uses client protein folding as its own cue for release. [Im7] (Mus musculus) PubMed

 17865.

Study determined the structure of the chromatin-tethering domain (CTD) of IE1 bound to the nucleosome core particle, and discovered that IE1-CTD specifically interacts with the H2A-H2B acidic patch and impairs the compaction of higher-order chromatin structure during infections. [IE1] (Mus musculus) PubMed

 17866.

These data suggest that N- and C-terminal domains of ZmSPMS1 play a role in a functional homodimer.[ZmSPMS1] (Mus musculus) PubMed

 17867.

FgSSN3 is important for secondary metabolism, sexual reproduction, and plant infection, as a subunit of mediator complex contributing to transcriptional regulation of diverse genes.[FgSsn3] (Mus musculus) PubMed

 17868.

Psm was mapped to a 170 kb region on chromosome 3 of cucumber and pentatricopeptide repeat (PPR) 336 was identified as the likely candidate gene for paternal sorting of mitochondria [PPR336] (Mus musculus) PubMed

 17869.

CaPPR6 is a strong candidate for the Restorer-of-fertility gene [PPR6] (Mus musculus) PubMed

 17870.

DetR is essential for Xanthomonas oryzae pv. oryzae virulence through the regulation of the Xoo defence system.[DetR] (Mus musculus) PubMed

 17871.

P5AP interaction with Pbp5 increases the resistance to cephalosporins. [P5AP, Pbp5] (Mus musculus) PubMed

 17872.

Collectively, these findings suggest that SpoVG is similar to global posttranscriptional regulators, a class of RNA-binding proteins that interact with noncoding RNA, regulate genes in concert with RNases, and control pleiotropic aspects of bacterial physiology.[SpoVG] (Mus musculus) PubMed

 17873.

PfHsp70-z appears to be marginally more effective in suppressing protein aggregation than its cytosol-localized partner, PfHsp70-1 (Mus musculus) PubMed

 17874.

Eng1 beta-glucanase promotes Histoplasma virulence by reducing levels of surface-exposed beta-glucans on yeast cells, thereby enabling Histoplasma yeasts to escape detection by the host beta-glucan receptor, Dectin-1. [Eng1] (Mus musculus) PubMed

 17875.

BtuC2D2 displays a strong conformational memory for this excited state, and takes hours to return to its basal state after catalysis terminates. [BtuC2D2] (Mus musculus) PubMed

 17876.

a post-developmental glial role for the PROS-1/Prospero/PROX1 homeodomain protein in sensory-neuron function in C. elegans, is described.[Prospero] (Mus musculus) PubMed

 17877.

These results suggest that, along with its primary function in sperm-oocyte fusion, TRP-3 induces Ca(2+) waves in fertilized oocytes, consistent with the conduit model.[TRP-3] (Mus musculus) PubMed

 17878.

distinct effects of nine Hsp90 mutations on activation of v-src and glucocorticoid receptor (GR), indicating that different chaperone mechanisms can be utilized for these clients.[HSP90] (Mus musculus) PubMed

 17879.

Data show that the cold shock protein CspA plays an important role in the virulence within macrophages: [CspA] (Mus musculus) PubMed

 17880.

he chimeric NHase (SBpNHase) from the thermal-sensitive BpNHase (NHase from Bordetella petrii) and the relatively thermal-stable PtNHase (NHase from Pseudonocardia thermophila) was constructed by swapping the corresponding C-domains (Mus musculus) PubMed

 17881.

The results of this study suggest that Xenopus Intl-3 is involved in the innate immune protection of the digestive tract against bacterial infections. [Intl-3] (Mus musculus) PubMed

 17882.

The C. glabrata FKBP12 structure shows no evidence of an intermolecular self-catalysis-like binding event. [FKBP12] (Mus musculus) PubMed

 17883.

C. albicans FKBP12 contains a proline residue at the tip of its 80s loop, Pro104, that, in the apo form, is inserted into the active site of a neighboring subunit. [FKBP12] (Mus musculus) PubMed

 17884.

FKBP12 structures reveal the insertion of a proline, conspicuously conserved in these proteins, into the active sites of adjacent molecules. [FKBP12] (Mus musculus) PubMed

 17885.

The expression of rgsA is regulated by GacA and RpoS and that it was essential for oxidative stress resistance. [rgsA] (Mus musculus) PubMed

 17886.

Gene PmAF7DS confers resistance to wheat powdery mildew [AF7DS] (Mus musculus) PubMed

 17887.

miR-375 directly targeted PDK1 in porcine pancreatic stem cells suppressing cell proliferation and differentiation into islet-like cells. [miR-375] (Mus musculus) PubMed

 17888.

Escherichia coli Trx83 with a truncated Trx fold induces peripheral blood mononuclear cells proliferation, but only in the disulfide-reduced form.[Thioredoxin] (Mus musculus) PubMed

 17889.

The role of NoxR in cellulose degradation [NoxR] (Mus musculus) PubMed

 17890.

Taken together, CgmA may function as an export system not only for the diamine putrescine and cadaverine but also for L-arginine. The major export system for L-lysine and L-arginine LysE may also play a role in L-citrulline export since production of L-citrulline was reduced when lysE was deleted and improved by 45 % when lysE was overproduced.[CgmA, LysE] (Mus musculus) PubMed

 17891.

BioH was confirmed to have a feruloyl esterase activity, [BioH] (Mus musculus) PubMed

 17892.

Spermidine synthase enzyme (spds) plays an essential role in the survival of Synechococcus sp. PCC 7942 under osmotic stress. (spds) (Mus musculus) PubMed

 17893.

This study shows that PIA has a significant role in the biofilm formation in S. epidermidis. [PIA] (Mus musculus) PubMed

 17894.

This study demonstrated that melatonin mediated proliferation, apoptosis, and steroidogenesis in porcine granulosa cells predominantly through the activation of melatonin receptor MT2 in vitro, which provided evidence of the beneficial role of melatonin as well as its functional mechanism in porcine granulosa cells in vitro.[melatonin receptor MT2] (Mus musculus) PubMed

 17895.

A third protein, KfiB, is required to stabilize the KfiAC complex in the bacteria and to transport this complex to the inner membrane where the initiation of polymerization occurs.[KfiC, KfiB] (Mus musculus) PubMed

 17896.

Amino acid residues I20 and L23 in the C-terminal portion of the Ler protein are critical for derepression of the LEE5 promoter. [Ler] (Mus musculus) PubMed

 17897.

results indicate (1) flrA, flrB and flrC are important for V. alginolyticus adhesion; (2) flrA, flrB and flrC influence adhesion, motility, biofilm formation and EPS production by controlling expression of key genes involved in those phenotypes; (3) flrA, flrB and flrC regulate adhesion in the natural environment with different temperatures, pH levels, salinities and starvation time [flrA, flrB, flrC ] (Mus musculus) PubMed

 17898.

Phosphorylation of nonmuscle and smooth muscle myosin by myosin light chain kinase (MLCK) is required for activation of myosin's ATPase activity.[ smooth muscle myosin II, nonmuscle myosin IIB] (Mus musculus) PubMed

 17899.

This study shows that at low environmental pH, biofilm formation in Streptococcus pyogenes is mediated by YvqE and suggests that regulation of pilus expression by environmental acidification could be directly under the control of YvqE.[YvqE] (Mus musculus) PubMed

 17900.

The results of this study revealed that the increased expression of UGT2B in the liver occurred during the maintenance phase of neuropathic pain, suggesting that it may be caused by transcriptional regulation which was not accompanied by increased nuclear import of pregnane X receptor (PXR). [UGT2B] (Mus musculus) PubMed

 17901.

The results suggest that relative abundance of G protein-coupled receptor 30 (GPR30) mRNA in the testis and epididymis is time-dependent and localization-specific during sexual maturation.[GPR30] (Mus musculus) PubMed

 17902.

Characteristics of the highly inducible promoter of the gene encoding the mitochondrial porin, the voltage-dependent anion channel (VDAC); promoter is recommended for use in new genetic constructs both in basic research for assessing the adaptive strategy of lower eukaryotes under adverse conditions and in designing new highly competitive transformants producing economically important compounds (Mus musculus) PubMed

 17903.

Three homeologous copies of the TaSMT1 gene for C24-sterol methyltransferase, which are located on chromosomes A, B, and D of Triticum aestivum hexaploid genome, were discovered. The bioinformatic analysis of the structure of these genes and sequencing de novo promoter sequences revealed differential expression of homeologous TaSMT1 genes in leaves and roots of wheat seedlings under normal conditions and in stress. (Mus musculus) PubMed

 17904.

MtMan26A showed high specific activity against konjac glucomannan and carob galactomannan, while it also exhibited high thermal stability with a half-life of 14.4 h at 60 degrees C.[Man26A] (Mus musculus) PubMed

 17905.

A study evaluating the genetic structure surrounding the OXA-48 carbapenemase gene of E. coli ST38 is reported.[OXA-48] (Mus musculus) PubMed

 17906.

N-termini of EntA and EntE are proximal in the intracellular complex [EntA][EntE] (Mus musculus) PubMed

 17907.

Data indicated an important role for the Ifchit1 chitinase as a virulence factor in I. fumosorosea [Ifchit1 chitinase]. (Mus musculus) PubMed

 17908.

IgD could possibly have a key role to play in the immune response when bacterial infections in Nile tilapia. IgD was cloned and expression analysis was performed. (Mus musculus) PubMed

 17909.

The results indicate that Fjoh_4430 is a novel glycoside hydrolase family 31 dextranase with high transglucosylation activity. [Fjoh_4430] (Mus musculus) PubMed

 17910.

The higher thermostability, higher affinity for pNPAra and wider activity over natural substrates shown by ABFII may be related to the presence of a CBM. The availability of the recombinant enzymes may be useful in biotechnological applications for the production of arabinose. (Mus musculus) PubMed

 17911.

Enzymatic properties, evidence for in vivo expression, and intracellular localization of shewasin D, the pepsin homolog from Shewanella denitrificans, have been described. (Mus musculus) PubMed

 17912.

Two NADP(+)-dependent isocitrate dehydrogenase isozymes, IDH-IIa, and IDH-IIb, from a psychrophilic bacterium, Colwellia psychrerythraea strain 34H, have been characterized. (Mus musculus) PubMed

 17913.

LpxL1 transfers a C12:0 secondary acyl chain to the 2'-position of lipid A, and LpxL2 transfers a C14:0 secondary acyl chain to the 2'-position primary acyl chain of lipid A. [ LpxL1, LpxL2] (Mus musculus) PubMed

 17914.

These findings revealed that the avenolide receptor AvaR1 functions as a transcriptional repressor for avenolide biosynthesis and its own synthesis.[AvaR1] (Mus musculus) PubMed

 17915.

A major QTL ( qRtsc8-1 ) was discovered that confers resistance to tar spot complex of maize [Rtsc8-1] (Mus musculus) PubMed

 17916.

mutation of the cpsJ gene influenced both the capsule synthesis and virulence of S. iniae (Mus musculus) PubMed

 17917.

4-Keto-d-arabonate synthase (4KAS) catalyzes the conversion of 2,5-diketo-D-gluconate to 4-keto-D-arabonate in D-glucose oxidative fermentation by Gluconobacter oxydans NBRC 3292. [4KAS] (Mus musculus) PubMed

 17918.

The linear antigenic domain of the NS is located at its C-terminal end (amino acid residues 481-627). [NP] (Mus musculus) PubMed

 17919.

Our results suggest that recombinant D-hydantoinase could be potentially applied in the synthesis of D-amino acids. (Mus musculus) PubMed

 17920.

This analysis shows that transcription factors abrB1941, abrB0310 and abrB3647 all participated in metabolically regulating acidogenesis, solventogenesis, and a two-phase transition in Clostridium acetobutylicum, but the AbrB0310 and AbrB3647 functions were the most important.[abrB1941, abrB0310, abrB3647] (Mus musculus) PubMed

 17921.

Taken together, the findings indicate that Trr1 could reduce Trx2-5 and hence dominate the intracellular redox state, profoundly affecting the potential of Beauveria bassiana against arthropod pests. Trr2 could reduce Trx1/6 but function only in the absence of Trr1.[Trr1, Trr2] (Mus musculus) PubMed

 17922.

RraAV1 plays an active role in RNase EV-mediated RNA cleavage in V. vulnificus. [RNase EV, RraAV1] (Mus musculus) PubMed

 17923.

These studies reveal critical contributions of AQP3 to A. gambiae heat tolerance and P. falciparum development in vivo. [AQP3] (Mus musculus) PubMed

 17924.

HxuC, HxuB, and HxuA proteins might have strong antigenicity (HxuC, HxuB, HxuA) (Mus musculus) PubMed

 17925.

PTENP1 overexpression results in the impairment of the insulin-signaling pathway and may function as a competing endogenous RNA for miR-499-5p, thereby contributing to insulin resistance. (PTENP1) (Mus musculus) PubMed

 17926.

). The study indicated the potential utility of rNS3DeltaHD fusion protein as candidate diagnostic reagent in developing an indirect-ELISA for sero-surveillance of animals for BTV antibodies under DIVA strategy, wherever monovalent/polyvalent killed BT vaccine formulations devoid of NS proteins are being practiced for immunization. (Mus musculus) PubMed

 17927.

These data demonstrated that polyphosphate kinase is endowed with a weak but clearly detectable phospholipase D activity.[polyphosphate kinase] (Mus musculus) PubMed

 17928.

S. aureus NCTC 8325-4 adheres to immobilized plasminogen in vitro and that the adhesion may be mediated by a C-terminal fragment of the PBP3 protein.[PBP3] (Mus musculus) PubMed

 17929.

These data indicate that Mdj1 plays a vital role in normal fungal development and contributes significantly to the biological control potential of Beauveria bassiana against insect pests.[Mdj1] (Mus musculus) PubMed

 17930.

We observed that direct administration of tobacco-derived Tb4 was more effective than Tb4 either obtained commercially or derived from expression in Escherichia coli at promoting splenocyte proliferation in vitro and wound healing in mice through an endothelial migration assay. (Mus musculus) PubMed

 17931.

The data generated in this study reveal that the response regulator SCO0204 greatly contributes to prevent the formation of actinorhodin in the sco2127 mutant, likely through the activation of some proteins associated with oxidative stress that include the nitrite producer SCO0216.[SCO0204] (Mus musculus) PubMed

 17932.

The study showed that ice nucleation of P. ananatis isolated from Maize White Spot depends on the presence of the ina gene in the bacterial genome (inaA). (Mus musculus) PubMed

 17933.

Inhibition of endogenous miR-199 led to physiological cardiac hypertrophy probably due to the up-regulation of PGC1alpha[miR199] (Mus musculus) PubMed

 17934.

findings show bphA expression in response to benzoate is confined to a 530-bp fragment from the bphA promoter region from -787 to -509 bp from the transcriptional start site; a benzoate-response element, consisting of a single 6-bp sequence within a 51-bp sequence in this region, is most likely to be involved in binding of 1 or more proteins that modulate the activity of the promoter in response to benzoic acid [bphA] (Mus musculus) PubMed

 17935.

The overexpression of CYP340W1 plays an important role in abamectin resistance in Plutella xylostella. (Mus musculus) PubMed

 17936.

Gamma-butyrobetainyl CoA synthetase from Agrobacterium sp. 525a has been cloned and characterized. [Gamma-butyrobetainyl CoA synthetase] (Mus musculus) PubMed

 17937.

High temperature increases the expression of both vuuA and crp by facilitating metabolism under iron-limited conditions. [vuuA, crp] (Mus musculus) PubMed

 17938.

A novel nucleoside hydrolase from Lactobacillus buchneri LBK78 catalyzing hydrolysis of 2'-O-methylribonucleosides has been characterized. [LbNH] (Mus musculus) PubMed

 17939.

Ser151, Asp244, and His274 consist of a catalytic triad, and Gly80, Gly81, and Ala152 compose an oxyanion hole of carboxylesterase.[Carboxylesterase] (Mus musculus) PubMed

 17940.

Crystallization of both the AMPPNP (an ATP analogue) and ADP bound forms of a novel CPN, classified as belonging to a third group. [CPN, group III] (Mus musculus) PubMed

 17941.

We identified a mutation in a splice acceptor site which leads to mis-splicing in exon 5 of TaGW2-A1. The mutant allele consistently increased grain weight and morphometric parameters in all environments and across all grains of the spike compared to the wild type full length TaGW2-A1 allele. [GW2-A1] (Mus musculus) PubMed

 17942.

Frost tolerance in durum wheat is mainly controlled by copy number variation of CBF-A14 at the Fr-A2 locus [Fr-A2] (Mus musculus) PubMed

 17943.

he native HA1 reacted well with conformational, cross-genotype, neutralizing monoclonal antibodies, whereas a loss of binding activity was noted with the denatured HA1 form. (Mus musculus) PubMed

 17944.

Expression of recombinant organophosphorus hydrolase capable of hydrolysis of nerve agents in the original producer of the enzyme, Sphingobium fuliginis ATCC 27551, has been reported. [Organophosphorus hydrolase] (Mus musculus) PubMed

 17945.

BnDWF1 is a major locus controlling plant height [DWF1] (Mus musculus) PubMed

 17946.

Treated purified human T cells with tetanus neurotoxin showed significant increase in IFN-gamma mRNA level and cytokine secretion, but not IL-4 and IL-17, following 48 h treatment. [tetanus neurotoxin] (Mus musculus) PubMed

 17947.

The presence of Mg(2+)-dependent Ecto-ATPDase on the surface modulates the nucleotide concentration and protects the parasite from the lytic effects of the nucleotides mainly ATP. [ecto-ATPDase] (Mus musculus) PubMed

 17948.

The inhibitory assay suggested that the C-terminal seven residues of the propeptide do not inhibit the cucumisin activity. The crystal structure of the cucumisin*propeptide complex revealed the regulation mechanism of cucumisin activity. (Mus musculus) PubMed

 17949.

These combined results suggest that the productive electron transfer complex of SiR and Fd could be formed through multiple processes of the electrostatic intermolecular interaction and this implication is discussed in terms of the multi-functionality of Fd in various redox metabolisms. (Mus musculus) PubMed

 17950.

The nrtA-disrupted strain was deficient in the uptake of nitrate. As a result, KA production in this strain was not considerably affected by the presence of nitrate. (Mus musculus) PubMed

 17951.

Data suggest novel roles for Protein O-mannosyltransferases (Pmt1) in negatively regulating conidiation and demonstrate that the C-terminal Pmt1 MIR-containing region is dispensable for enzymatic activity and organismal virulence [Pmt1]. (Mus musculus) PubMed

 17952.

The poCRIP1 showed 89% and 93% homologous with human and cattle, respectively. And it also contained one conserved domain, LIM-CRIP domain. Meanwhile, the genomic structure and promoter map was done and several conserved transcriptional regulatory sites were also predicted in this study. (CRIP1) (Mus musculus) PubMed

 17953.

Mac is not essential for S. suis virulence in strain P1/7 in natural healthy host without specific IgM. [Mac] (Mus musculus) PubMed

 17954.

We established a method for determining both tandem repeat numbers and IS6110 insertion in the QUB11a locus of M. tuberculosis using capillary electrophoresis analysis and BsmBI digestion (Mus musculus) PubMed

 17955.

The A. oryzae genome is predicted to have three transketolase genes and overexpression of AO090023000345, one of the three genes, resulted in phenotypic change and further increase (corresponding to an increased production of 0.38 mmol/g dry cell weight) in free fatty acids at 1.4-fold compared to the faaA disruptant. (Mus musculus) PubMed

 17956.

Expression and biological activity of two types of interferon genes in medaka (Oryzias latipes)[IFNa and IFNd] (Mus musculus) PubMed

 17957.

A cystatin F homologue from large yellow croaker (Larimichthys crocea) inhibits activity of multiple cysteine proteinases and Ii chain processing in vitro [cystatin F] (Mus musculus) PubMed

 17958.

glandless gene Gl2(e), a MYC transcription factor, is essential for pigment gland formation and serves as a vital positive regulator in the organogenesis pathway of pigment gland [Gl2(e] (Mus musculus) PubMed

 17959.

sequencing data revealed that expression levels of cellulase genes were significantly decreased by the mutation as reported previously. expression levels of various hemicellulolytic enzyme genes, several extracellular protease genes, the nosA and rosA genes involved in sexual development, and AN4394 encoding an ortholog of EcdR involved were also significantly decreased by the mutation (Mus musculus) PubMed

 17960.

Upon exposure to hypoxic stress, the fungus accumulated more ThiA and NmtA proteins, and more thiamine than under aerobic conditions. The thiA gene was required for the fungus to upregulate hypoxic branched-chain amino acids and ethanol fermentation that involve enzymes containing TPP. (Mus musculus) PubMed

 17961.

PRRSV E protein interacts with host ATP5A and induces apoptosis by inhibiting ATP production. (Mus musculus) PubMed

 17962.

30Kc19alpha shows even higher protein delivery activity than did whole 30Kc19 protein and has low cytotoxicity when added to cell culture medium. Therefore, based on its multifunctional properties, 30Kc19alpha can be developed as a novel candidate for a therapeutic protein carrier into various cells and tissues. (Mus musculus) PubMed

 17963.

The results suggested that the protein encoded by the iron-regulated gene ireA has roles in adhesion and stress resistance in avian pathogenic E. coli. [ireA] (Mus musculus) PubMed

 17964.

New SNP markers that can be used for marker-assisted selection and map-based cloning saturate the chromosome region carrying SrCad, a wheat gene that confers resistance to Ug99 stem rust. [SrCad] (Mus musculus) PubMed

 17965.

VacJ plays an essential role in maintaining outer membrane integrity, stress tolerance, biofilm formation, serum resistance, and adherence to and invasion of host cells suggesting a putative role of VacJ lipoprotein in virulence regulation. [VacJ] (Mus musculus) PubMed

 17966.

These results suggest that WspA plays roles in endocytosis at hyphal tips and polarity establishment during germination (Mus musculus) PubMed

 17967.

The findings suggest that endogenous Pointed homologs are directly and indirectly involved in the repression of E. coli-mediated lebocin promoter activation in Bombyx mori cells. [PNT2] (Mus musculus) PubMed

 17968.

These activities were also measured in the presence of selective inhibitors for cysteine proteinases demonstrating their source as cathepsin-like proteinases. (Mus musculus) PubMed

 17969.

The combination of three non-functional alleles of the flowering repressor VRN2 results in a spring growth habit in wheat. [VRN2] (Mus musculus) PubMed

 17970.

Three putative deuterolysin (EC 3.4.24.29) genes (deuA, deuB, and deuC) were found in the Aspergillus oryzae genome database.Three putative deuterolysin (EC 3.4.24.29) genes (deuA, deuB, and deuC) were found in the Aspergillus oryzae genome database (Mus musculus) PubMed

 17971.

These results suggested that the loss of alpha-1,3-glucan in the DeltakexB was compensated by increases in the chitin content and the average degree of beta-1,3-glucan polymerization (Mus musculus) PubMed

 17972.

Wistar rats with collagen-induced arthritis were intramuscularly injected with the recombinant plasmid pcDNA/sTNF-BD encoding the sequence of the TNF-binding protein domain of variola virus CrmB protein (VARV sTNF-BD) or the pcDNA3.1 vector, histopathological changes in the hind-limb joints of rats were most severe in the animals injected with pcDNA3.1 and much less severe in the group of rats injected with pcDNA/sTNF-BD (Mus musculus) PubMed

 17973.

Mep45 serves as a main pathway through which small solutes diffuse across the outer membrane of this bacterium [Mep45] (Mus musculus) PubMed

 17974.

sexual development-promoting region of Schizophyllum commune TRP1 gene [TRP1] (Mus musculus) PubMed

 17975.

We identified two sorbitol-induced genes (designated as sorA and sorB), cloned their promoters, and built a regulated egfp and brlA expression system. Growth medium-dependent enhanced green fluorescence protein (EGFP) fluorescence and conidiation were confirmed for egfp and brlA under the control of their respective promoters (Mus musculus) PubMed

 17976.

APRR2 is associated with chloroplast development and controls white immature fruit color [APRR2] (Mus musculus) PubMed

 17977.

epinephrine may influence the development of the beta2-adrenoceptor-mediated responses at birth and the rabbit is an excellent model to study these issues.[beta2 adrenergic receptor] (Mus musculus) PubMed

 17978.

The indel in the promoter of CsHDZIV11 co-segregates with fruit spine density [HDZIV11] (Mus musculus) PubMed

 17979.

These results indicate that the CTPA affects growth and thereby citric acid metabolism of A. niger changes, especially in early-log phase, but not citric acid-producing period. This is the first report showing that disruption of ctpA causes changes of phenotypes in relation to citric acid production in A. niger (Mus musculus) PubMed

 17980.

stabilization mechanism of monomeric cytochrome c5 from deep-sea piezophilic Shewanella violacea [cytochrome c5] (Mus musculus) PubMed

 17981.

PilA is involved in host colonization and pathogenesis. [pilA] (Mus musculus) PubMed

 17982.

Hepatitis E virus ORF1 encoded macro domain protein interacts with light chain subunit of human ferritin and inhibits its secretion. (Mus musculus) PubMed

 17983.

The Sm1 region in wheat was inverted relative to B. distachyon and rice, which suggests a chromosomal rearrangement within the Triticeae lineage. [Sm1] (Mus musculus) PubMed

 17984.

Data provide evidence that Pum1 is repressive for filamentation during vegetative growth through auto-regulation, and is supportive of filamentation in part through indirect stabilization of ZNF2, which in turn drives PUM1 expression during sexual development. [Pum1] and [ZNF2] (Mus musculus) PubMed

 17985.

two hypothetical Schizosaccharomyces pombe genes, SPBC409.08 and SPAC9.02c, which show sequence similarity to spermine family transporters and polyamine N-acetyltransferases, respectively, were characterized.[SPBC409.08 and SPAC9.02c] (Mus musculus) PubMed

 17986.

characterization of the novel alpha-1, 3-galactosyltransferase WclR from Escherichia coli O3 [WclR] (Mus musculus) PubMed

 17987.

Exiguobacterium antarcticum B-7 uses GH1 beta-glucosidase oligomerization as a strategy for cold adaptation. [GH1 beta-glucosidase] (Mus musculus) PubMed

 17988.

MoSPA2 is required for vegetative hyphal growth and maintaining conidium morphology and that spotted accumulation of MoSpa2 is important for its functions during cell polar growth. [MoSPA2] (Mus musculus) PubMed

 17989.

High glucose could inhibit osteogenic differentiation of mesenchymal stem cells by lncRNA AK028326 mediated down-regulation of CXCL13 expression. (Mus musculus) PubMed

 17990.

AoAtg26 plays an important role for autophagic degradation of organelles in A. oryzae [Atg26] (Mus musculus) PubMed

 17991.

Study investigated the mutant spadix (spd) that was generated by X-ray mutagenesis in the 1950s and terminates sexual development after the formation of pre-fruiting bodies (protoperithecia); generation of deletion strains revealed that only spd4 is required for fruiting body formation. Results point to SPD4 as a specific determinant of fruiting body formation. [SPD4] (Mus musculus) PubMed

 17992.

Tagging of diacylglycerol acyltransferase gene in mutant H4 resulted in reduced pathogenicity, indicating possible role of this gene in pathogenicity of C. gloeosporioides [diacylglycerol acyltransferase]. (Mus musculus) PubMed

 17993.

Rht-B1b and Rht-D1b genes significantly reduced coleoptile length [Rht-B1b; Rht-D1b] (Mus musculus) PubMed

 17994.

The results revealed clear differences in the MIR168 promoter sequence of monocot and dicot plant species. Moreover, the pattern of MIR168 promoter expression differed between monocots and dicots. These results suggest that, unlike that of miR168, the MIR168 promoter is not conserved in monocots and dicots. (Mus musculus) PubMed

 17995.

study identified the sRNAs expressed in B. melitensis 16M and its otpR mutant; identified the OtpR regulated cis- and trans-encoded sRNAs in B. melitensis expressed under acidic stress [OtpR]. (Mus musculus) PubMed

 17996.

Although cipC was not essential, its deletion attenuated Aspergillus fumigatus virulence in a low-dose murine infection model, suggesting the involvement of the cipC gene in the virulence of this fungus. (Mus musculus) PubMed

 17997.

Ly2.1-3 all possess a conserved LU domain and adopt similar three-finger structure with human CD59, SLURP1 and other Ly6 family members. Ly2.1-3 cluster on chromosome 2 and share high homology, possibly originated from chromosomal gene duplication.[Ly2.1,Ly2.2,Ly2.3] (Mus musculus) PubMed

 17998.

study suggested that BmLeb5 might play an important role in the immune response of silkworm to defend B. bassiana infection. (Mus musculus) PubMed

 17999.

MCR-1 was detected yearly in European food-producing animal since 2004 with a high diversity of pulsotypes supporting the dissemination of mcr-1 via plasmids.[MCR-1] (Mus musculus) PubMed

 18000.

Inhibition of BDNF-AS is a novel method to protect ketamine-induced neurotoxicity in mouse embryonic neural stem cell-derived neurons.[BDNF-AS] (Mus musculus) PubMed

 18001.

Slx5/8 allows for passage through mitosis when replication stress is tolerable.[Slx5, Slx8] (Mus musculus) PubMed

 18002.

The deletion of rtfA notably reduced the production of aflatoxin B1, indicating that rtfA is a regulator of mycotoxin biosynthesis in A. flavus. In addition, the deletion rtfA also altered the production of several unknown secondary metabolites [rtfA] (Mus musculus) PubMed

 18003.

The charge mobility of bacteriorhodopsin was theoretically investigated using extended Marcus-Hush theory. Charge mobilities of 1.3 x 10(-2) and 9.7 x 10(-4) cm(2)/(V s) for hole and electron transfer, respectively, were determined. The computed electron mobility is comparable to experimentally measured values (9 x 10(-4) cm(2)/(V s)). [bacteriorhodopsin] (Mus musculus) PubMed

 18004.

identification of a a novel pre-harvest sprouting resistance allele TaSdr-A1a mainly presented in Chinese landraces (Mus musculus) PubMed

 18005.

discovery of a novel partial adult plant resistance gene, named Lr75 [Lr75] (Mus musculus) PubMed

 18006.

The Rht-B1 locus governing plant height was found to have a strong effect in modulating Fusarium head blight (FHB) severity. The negative effect of the semi-dwarf allele Rht-B1b on FHB resistance was compensated by combining with Fhb1 and additional resistance QTL. [Rht; Fhb1] (Mus musculus) PubMed

 18007.

mapping of eyespot resistance genes Pch1 and Pch2 to wheat chromosome 7D and 7A, respectively; these two genes are not homoeoloci [Pch1; Pch2] (Mus musculus) PubMed

 18008.

Os05g03040, which putatively encodes an APETALA2 transcription factor, is the most probable candidate gene for qHD5, a novel major QTL with pleiotropism for yield-related traits [Os05g03040] (Mus musculus) PubMed

 18009.

Ipk1 is the major IP5 kinase in C. neoformans. Ipk1 is essential for pathogenicity but that its contribution relates more to its indirect role in PP-IP5/IP7 production, rather than its direct role in producing IP6. (Mus musculus) PubMed

 18010.

three critical amino acid residues of N. crassa NCS-1 and its functional conservation across species using the orthologue from R. norvegicus (Mus musculus) PubMed

 18011.

Data suggest that miR-674-5p (microRNA-674-5p) serves as a negative regulator in 5-LO (arachidonate 5-lipoxygenase) mediated autoimmune liver injury; miR-674-5p represses expression of 5-LO in hepatocytes in the presence of IL-6 (interleukin-6) or TNFa (tumor necrosis factor-alpha). [MIRN674; microRNA-674] (Mus musculus) PubMed

 18012.

Compared with TBK1, TBK1L contains an incomplete S_TKc domain, and lacks UBL_TBK1_like domain. Overexpression of TBK1 but not TBK1L resulted in significant activation of zebrafish IFN1 and IFN3 promoters. Similarly, TBK1L had little impact on the antiviral state of the cells.[TBK1L] (Mus musculus) PubMed

 18013.

the stem rust resistance gene SrTA10187 was mapped to wheat chromosome 6 [SrTA10187] (Mus musculus) PubMed

 18014.

These data suggest that the PriA protein is needed for survival and persistence of Helicobacter pylori in mice stomach mucosa.[PriA] (Mus musculus) PubMed

 18015.

the close association of the SXT resistance gene sul2 with transposase in S. maltophilia isolates.[sul2] (Mus musculus) PubMed

 18016.

CsSEP2 is involved in the floral organ and fruits development by conferring transcriptional activity.[CsSEP2] (Mus musculus) PubMed

 18017.

Ms-cd1, the dominant genic male sterile gene, was mapped to a 39.4-kb DNA fragment between two InDel markers, InDel14 and InDel24. A newly predicted ORF designated Bol357N3 was identified as the candidate of the Ms-cd1 gene. (Mus musculus) PubMed

 18018.

To clarify the role of m(5) U54 and TrmFO in the network, we constructed the trmFO gene disruptant (trmFO) strain of T. thermophilus. Although this strain did not show any growth retardation at 70 degrees C, it showed a slow-growth phenotype at 50 degrees C (Mus musculus) PubMed

 18019.

Study shows that the phoU mutation differentially affects the transcription of ppk and ppx, that respectively, encode a polyP kinase and a polyP exopolyphosphatase, by increasing the former and reducing the latter, further contributing the accumulation of polyP. [ppk, ppx] (Mus musculus) PubMed

 18020.

OsDT11 overexpression dramatically enhances tolerance to drought and had reduced water loss, reduced stomatal density, and an increased the concentration of abscisic acid (ABA). [encoded by LOC_Os11g10590] (Mus musculus) PubMed

 18021.

Putative cysteine protease (G9S4N1) closely related to RgpB of Porphyromonas gingivalis. G9S4N1 lacks obvious propeptide that behaves as inhibitor of proteases and was proven to be a propeptide-independent protease. Unlike RgpB, which exclusively cleaves ArgXaa bonds, G9S4N1 exhibits both arginine- and citrulline-specific activities [cysteine protease G9S4N1]. (Mus musculus) PubMed

 18022.

SHG10 keratinolytic alkaline protease was purified; It exhibited full stability at pH (6.0-11.0) at 4 degrees C and at 65 degrees C; enhanced enzyme activity was retained in presence of commercial laundry detergents and organic solvents [SHG10 keratinolytic alkaline protease] (Mus musculus) PubMed

 18023.

The findings strongly support an important role for PLY in the initial establishment nasal colonization.[PLY] (Mus musculus) PubMed

 18024.

Results provide evidence that disruption of YLR162W in S. cerevisiae results in increased tolerance to organic solvents. (Mus musculus) PubMed

 18025.

Significant effects of interaction between Glu-1 and Glu-3 loci on technological properties of wheat grains [Glu-1; Glu-3] (Mus musculus) PubMed

 18026.

The present study suggested that both TgENO2 and TgTrxLp were potential candidates for the development of multicomponent vaccines against toxoplasmosis. (Mus musculus) PubMed

 18027.

characterization of homC polymorphism as well as an analysis of the distribution of the various forms of homC across 160 clinical isolates; investigate the association between homC and the bab gene family; in American H. pylori clinical isolates, there was a significant association between homC (L) and carriage of babA at locus A [HomC] (Mus musculus) PubMed

 18028.

This study shows that the memetic algorithms used are effective for enforcing the ligand diffusion and cavity exploration in the P450cam-camphor complex. [P450cam] (Mus musculus) PubMed

 18029.

KlMig1p may exert a negative regulatory function on cell wall biosynthesis. (Mus musculus) PubMed

 18030.

SteA binds phosphatidylinositol 4-phosphate for subcellular targeting within host cells.SteA co-localizes with mammalian host cell membranes.[SteA] (Mus musculus) PubMed

 18031.

miR-181a-5p promotes myogenic apoptosis by targeting GRP78 in C2C12 cells. (Mus musculus) PubMed

 18032.

A single dominant gene, called Ndhrl1, controls the nitrogen-dependent lesion mimic phenotype [Ndhrl1] (Mus musculus) PubMed

 18033.

The role of Shiga-toxigenic Escherichia coli O113:H21 subAB gene in stress granule formation [subAB] (Mus musculus) PubMed

 18034.

mapping of the stem rust resistance genes SrTmp, SrCad, and Sr42 [SrTmp; SrCad; Sr42] (Mus musculus) PubMed

 18035.

These results suggest that DNL3 plays important roles in rice leaf morphogenesis and vegetative development. (Mus musculus) PubMed

 18036.

MtVRN2 represses the transition to flowering in Medicago by regulating the onset of expression of the potent floral activator, FTa1. [VRN2, FTa1] (Mus musculus) PubMed

 18037.

mammalian Hsp70 displayed a high specificity for negatively charged phospholipids, such as phosphatidyl serine, whereas DnaK interacted with all lipids tested regardless of the charge.[DnaK] (Mus musculus) PubMed

 18038.

The cold induction of rbp1 is regulated at a posttranscriptional level through the 5' untranslated region. [rbp1] (Mus musculus) PubMed

 18039.

the TfoX homolog TfoY as a second activator of the Type VI secretion systems.[TfoX, TfoY] (Mus musculus) PubMed

 18040.

OsSIRP1 acts as a negative regulator of salinity stress tolerance mediated by the ubiquitin 26S proteasome system. [OsSIRP1] (Mus musculus) PubMed

 18041.

The above results demonstrated that the P331 site of CYP102A3 also plays an important role in the n-octane oxidation and CYP102A3 is a functionally flexible biocatalyst that can be optimized for a variety of industrial applications. (Mus musculus) PubMed

 18042.

[MYB138] - transcription factor localized in nucleus promotes embryonic callus formation through GA signal transduction (Mus musculus) PubMed

 18043.

This study's results suggested that Lc-NK-lysin is a typical member of the NK-lysin family and as an immune-related gene it is involved in the immune response when pathogens invade.[NK-Lysin] (Mus musculus) PubMed

 18044.

CagA-positive H. pylori strains containing a large number of EPIYA-C phosphorylation sites induce a decrease in D cell number and an increase in G cell number.[cagA] (Mus musculus) PubMed

 18045.

[caroxylesterase (CarE)] - characterization and role in malathion detoxification (Mus musculus) PubMed

 18046.

The recombinant protein showed enantioselectivity that was distinct from other fungus Epoxide hydrolases (EHs), making this protein a potential biotechnological tool. (Mus musculus) PubMed

 18047.

Ctr4 may play various roles in addition to copper transporter in C. neoformans, such as signal transduction and maintenance of cell wall/membrane integrity. (Mus musculus) PubMed

 18048.

results did not strongly support the hypothesis that a male's avpr1a genotype predicts courtship behaviours measured, suggesting that other courtship behaviours or traits, such as odour and vocalizations, may be more important to female prairie voles when choosing mates [avpr1a] (Mus musculus) PubMed

 18049.

Expression analyses showed that the three genes were all rapidly and significantly upregulated in vivo after poly (I:C) challenge in peripheral blood, liver, spleen and head kidney tissues. The results indicate that the LcMDA5, LcLGP2 and LcMAVS might play important roles in antiviral immune responses. [LGP2] (Mus musculus) PubMed

 18050.

W483A was also easily denatured by DTT, an outer disulfide bond breaker, compared to the wild-type. CBM3c could influence the surface stability. These features of CBM3c result from the hydrophobic interaction of tryptophan with the catalytic domain that is unrelated to substrate binding. (Mus musculus) PubMed

 18051.

The level of CYP3A1 was significantly lower in foetal liver compared with that in maternal liver according to Western blot data, suggesting a decreased metabolism and prolonged half-life of roxithromycin in the foetus. (Mus musculus) PubMed

 18052.

CPj0783 might cause abnormal vesicle-mediated transport by interacting with HIP14. [ CPj0783 ] (Mus musculus) PubMed

 18053.

The lacc gene encoding S. meliloti laccase was cloned and characterized. The full-length sequence of 1950bp encoded a protein of 649 aa preceded by a signal peptide consisting of 26aa. (Mus musculus) PubMed

 18054.

The results suggested that medaka Mep50 could be a partner of Prmt5 and might play major roles in a variety of tissues in medaka [Mep50] (Mus musculus) PubMed

 18055.

Study demonstrates the resuscitation-promoting activities of recombinant YeaZ from V. harveyi SF-1. The protein also promoted resuscitation of the VBNC wild-type and mutant cells, which were maintained at 4 degrees C for 120 days and not recovered by temperature upshift method. Disruption of yeaZ decreased the virulence of V. harveyi in zebrafish. [YeaZ] (Mus musculus) PubMed

 18056.

These results provide insights into the biological function and characterization of the RsMYB28 and RsMYB29 genes, and facilitate further dissection of the molecular regulatory mechanism underlying the glucosinolate biosynthesis in radish. [RsMYB28, RsMYB29] (Mus musculus) PubMed

 18057.

The results indicate that rCsCD94 is a key factor in the bactericidal and phagocytic effects of tongue sole, and reveal for the first time an essential role of fish CD94 in antibacterial immunity, thereby adding insight into the function of CD94.[CD94] (Mus musculus) PubMed

 18058.

TBEV Nonstructural Protein 1 [NS1] protein both triggers ROS production and activates a defense Nrf2/ARE pathway. These data suggest that a role of redox-mediated processes in TBEV-induced damage of the central nervous system should also be explored [Nonstructural Protein 1 [NS1]. (Mus musculus) PubMed

 18059.

OsPHR4 mediates the regulation of Phosphate-starvation signaling and Pi-homeostasis in a PHR1-subfamily dependent manner in rice.[OsPHR4] (Mus musculus) PubMed

 18060.

The fluctuations in adiponectin and orexin A (OXA) and orexin B (OXB) concentrations in the plasma and uterine lining fluid (ULF) suggest that the hormones present in ULF are mostly of local origin and that these hormones participate in the processes that accompany early pregnancy.[OXA; OXB] (Mus musculus) PubMed

 18061.

The expression of guanine nucleotide-binding alpha S subunit in the testis and epididymis of sheep at 1, 6, and 12 months of age is reported.[Galphas] (Mus musculus) PubMed

 18062.

Results suggest that xylanase CbXyn10B is stabilized with distinct rigidity at the catalytic cleft as well as the terminal regions for accommodating the functional needs to high temperature: [xylanase CbXyn10B] (Mus musculus) PubMed

 18063.

bacterial C2c2 possesses a unique RNase activity responsible for CRISPR RNA maturation that is distinct from its RNA-activated single-stranded RNA degradation activity. These dual RNase functions are chemically and mechanistically different from each other and from the crRNA-processing behaviour of the evolutionarily unrelated CRISPR enzyme Cpf1 [C2c2] (Mus musculus) PubMed

 18064.

Analysis of tissue distribution revealed that kiss2 and kissr2 transcripts were predominantly expressed in the brain and gonads, with expression levels in females higher than those in males. Moreover, kiss2 and kissr2 both showed significantly higher expression in brains and gonads during puberty [kissr2] (Mus musculus) PubMed

 18065.

Pathogen-specific IgY may provide a valuable treatment for vibriosis infection and can be a promising food additive. (Mus musculus) PubMed

 18066.

data support the hypothesis that L. monocytogenes isolated from food have attenuated invasion due to the presence of inlA premature stop codons. This information would be critically needed for adequate risk-assessments of the foodborne illness burden associated with L. monocytogenes strains (Mus musculus) PubMed

 18067.

RraAS1 directly interacts with catalytic domain of RNase ES to exert its inhibitory effect; rraAS1 gene deletion results in higher growth rate and increased production of of actinorhodin and undecylprodigiosin, compared with wild-type, suggesting RraAS1-mediated regulation of RNase ES activity contributes to modulating the cellular physiology of S. coellicolor [RraAS1, RNase ES ] (Mus musculus) PubMed

 18068.

long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan [Morrbid RNA] (Mus musculus) PubMed

 18069.

study showed that the emrB gene deletion mutant has pleiotropic effects on cell physiology and may affect the intrinsic susceptibility of bacteria towards colistin, other antibiotics and environmental conditions; together, this study suggests a possible contribution of the EmrAB system to colistin susceptibility [EmrA, EmrB] to colistin susceptibility (Mus musculus) PubMed

 18070.

[ZAT8] - regulates phosphorus acquisition, reactive oxygen species homeostasis and root system establishment (Mus musculus) PubMed

 18071.

the cystine importer (dgeo_1986) was identified and characterized; the absorbed cystine via this cystine-specific importer may be converted into cysteine, which acts as a primitive defense substrate that non-enzymatically scavenges oxidative stress agents [dgeo_1986] (Mus musculus) PubMed

 18072.

[ASR1] - may function as a transcription factor that provides drought stress resistance by inducing the production of reactive oxygen species-scavenging enzymes and non-enzymatic antioxidants (Mus musculus) PubMed

 18073.

The expression of emm1 and sda1 or lack thereof determine the pattern of invasive and non-invasive Streptococcus pyogenes disease in Aichi, Japan. [sda1] (Mus musculus) PubMed

 18074.

Results showed that Rhodospirillum rubrum wild-type strain produces unsubstituted, 3-OH and 3-oxo-substituted N-acylhomoserine lactones with acyl chains ranging from 4 to 14 carbons, with 3-OH-C8 being the most abundant. (Mus musculus) PubMed

 18075.

Molecular conformation of the active site of uridine phosphorylase and uridine phosphorylase substrate specificity (Mus musculus) PubMed

 18076.

The wscA deletion mutant does not form Woronin bodies anymore, but shows normal growth, colony morphology and conidiation. targeting of HexA-GFP is independent of WscA. [WscA] (Mus musculus) PubMed

 18077.

This study adds to this divergence by indicating a nonredundant role for PI3KC2alpha, with no role for PI3KC2beta, in regulating platelet OCS structure and overall platelet-dependent thrombus stability. (Mus musculus) PubMed

 18078.

OsJRL plays an important role in cell protection and stress signal transduction. [OsJRL (Mus musculus) PubMed

 18079.

[PIP2;4N] - controls leaf hydraulic capacitance and resistance (Mus musculus) PubMed

 18080.

PpEst is a novel poly(1,4-butylene adipate-co-terephthalate) degrading polyesterase identified by proteomic screening of Pseudomonas pseudoalcaligenes. [PpEst] (Mus musculus) PubMed

 18081.

the fertility restorer gene BrRfp1 was mapped to a 12.6-kb region containing a potential candidate gene encoding pentatricopeptide repeat-containing protein (Mus musculus) PubMed

 18082.

solution structure of SecB, a chaperone that exhibits strong antifolding activity, in complex with alkaline phosphatase and maltose-binding protein captured in their unfolded states [secB] (Mus musculus) PubMed

 18083.

Overexpression of SigB can dramatically enhance ccrAB transcription and staphylococcal cassette chromosome mec excision in methicillin-resistant Staphylococcus aureus strain N315, revealing an important role for this alternative sigma factor in the lateral transfer of SCCmec staphylococcal cassette chromosome mec.[SigB, ccrA, ccrB] (Mus musculus) PubMed

 18084.

purification and characterization of a cytosolic trehalase (TreH) from a thermoacidophilic archaeon Sulfolobus acidocaldarius [TreH] (Mus musculus) PubMed

 18085.

Xlnd is localized at cell wall. [Xlnd] (Mus musculus) PubMed

 18086.

[popW] - when transformed into tobacco primed antioxidant responses, increased tolerance to drought stress in tobacco plants (Mus musculus) PubMed

 18087.

Pch1 was the main effective source for reducing eyespot disease score in the European wheat varieties [Pch1] (Mus musculus) PubMed

 18088.

Fine mapping of the closely linked rust resistance genes Yr47 and Lr52 [Yr47; Lr52] (Mus musculus) PubMed

 18089.

Analysis of the ionic interaction between the hydrophobin RodA and two cutinases of Aspergillus nidulans obtained via an Aspergillus oryzae expression system has been presented. [CutL1] (Mus musculus) PubMed

 18090.

The results obtained in this study show that administration of pcDNA3/NS3-DEN3 induces a favorable response in the activation of T lymphocytes with low production of specific antibodies against NS3-DEN3. (Mus musculus) PubMed

 18091.

Fine mapping identified a candidate gene, CsSUN, that codes for round fruit shape [SUN] (Mus musculus) PubMed

 18092.

As HDAC5 expression may help nullify AIS and identify progenitor cells, the precise delivery of miD2861 may serve as a vehicle for monitoring network remodeling with target specificity and signal sensitivity after drug exposure that identifies brain repair processes in adult animals. (Mus musculus) PubMed

 18093.

Two amino acid residues in DRpAS variants (DRpAS Q299K and DRpAS Q299R) are involved in acceptor binding. [DRpAS] (Mus musculus) PubMed

 18094.

[MOT1] - required for molybdenum transport (Mus musculus) PubMed

 18095.

Eap was found to interfere with growth factor-stimulated activation of the mitogen-activated protein kinase (MAPK) pathway that is known to be responsible for cell shape modulation, induction of proliferation and migration of epithelial cells.[Eap] (Mus musculus) PubMed

 18096.

In summary the data identify a unique saeS allele (saeS(SKT)) which appears to override cell-density dependent SaeR and PVL expression in ST30 CA-MRSA isolates.[saeS, SaeR, Panton-Valentine leukocidin] (Mus musculus) PubMed

 18097.

Bioinformatics analysis suggested that an orphan sensor histidine kinase, CPE1757 (renamed RevS), was the cognate sensor of RevR.[RevS, RevR] (Mus musculus) PubMed

 18098.

The authors propose that ChiS plays a vital role in Vibrio cholerae pathogenesis.[ChiS] (Mus musculus) PubMed

 18099.

findings establish Frizzled proteins as physiologically relevant receptors for TcdB in the colonic epithelium [TcdB] (Mus musculus) PubMed

 18100.

study reports RraAS2 requires both scaffold domains of RNase ES for high-affinity binding and inhibitory action on the ribonucleolytic activity; results indicate that RraAS2 is a protein inhibitor of RNase ES and provide clues to how this inhibitor affects the ribonucleolytic activity of RNase ES [RraAS2] (Mus musculus) PubMed

 18101.

Overall, these data suggest that H-NS represses pelD, and by inference, other pel genes, by a cooperative binding mechanism, through oligomerization of H-NS molecules.[H-NS, pelD] (Mus musculus) PubMed

 18102.

rCsPTX1 displayed apparent bacteriostatic activity against Pseudomonas fluorescens in vitro by influencing the permeability of the microbial envelope. When introduced in vivo, rCsPTX1 enhanced the host's resistance to bacterial infection. The results indicate that CsPTX1 is a classic pattern recognition molecule that defends C. semilaevis against bacterial infection (CsPTX1). (Mus musculus) PubMed

 18103.

Dominant expression of trissin in the frontal ganglion indicates its possible role in the regulation of foregut-midgut contractions and food intake. (Mus musculus) PubMed

 18104.

Data showed that Actinobacillus (Aggregatibacter) actinomycetemicomitans GroEL protein has an antigenic effect on human primary monocytes. Aa GroEL protein responsive CD14 monocytes stimulates the expression of IL12, IL10, IFNG and TNFalpha cytokines with different kinetics and expression profile. [GroEL] (Mus musculus) PubMed

 18105.

The pathway to GTPase activation of elongation factor SelB on the ribosome. (Mus musculus) PubMed

 18106.

findings indicated that lincRNA-p21 inhibited development of human prostate cancer partly by regulating p53 downstream gene expression and partly by apoptotic activation[lincRNA-p21] (Mus musculus) PubMed

 18107.

NS5A contributes to reactive oxygen species production by activating expression of NADPH oxidases 1 and 4 as well as cytochrome P450 2E1.[NS5A] (Mus musculus) PubMed

 18108.

our results demonstrate that serum HCMV-miR-US4-1 can serve as a novel biomarker for predicting the outcome of IFNalpha treatment in chronic hepatitis B patients (Mus musculus) PubMed

 18109.

cinnamate 4-hyroxylase/C4H Results showed that C4H function is important for the normal development, but its transcriptional regulation does not correlate with quercetin as an efficient phenolic compound for walnut rhizogenesis. (Mus musculus) PubMed

 18110.

Molecular modeling and site-directed mutagenesis analyses demonstrated that Thermoanaerobacterium thermosaccharolyticum DSM 571Glycerol dehydrogenases (TtGlyDH) had an atypical dinucleotide binding motif (GGG motif) and a basic residue Arg(43), both related to dinucleotide binding [Glycerol dehydrogenase]. (Mus musculus) PubMed

 18111.

Superoxide dismutase and catalase act synergistically to protect the repair of photosystem II during photoinhibition in Synechococcus elongatus PCC 7942.[superoxide dismutase] [catalase] (Mus musculus) PubMed

 18112.

structure of Lysinibacillus sphaericus BinAB solved de novo by serial-femtosecond crystallography at an X-ray free-electron laser [BinA , BinB] (Mus musculus) PubMed

 18113.

HMG-CoA reductase activities of mutant MvaA proteins in the temperature sensitive mutants were lower than that of wild-type MvaA protein. Our findings from genetic and biochemical analyses suggest that mevalonate produced by HMG-CoA reductase is required for peptidoglycan synthesis for S. aureus cell growth. (Mus musculus) PubMed

 18114.

Dark-induced senescence activates OsSAG12-2 expression. Down-regulation of OsSAG12-2 in the transgenic artificial miRNA lines results in enhanced salt- and UV-induced cell death, even though it does not affect cell viability in the stress-free condition. Our results show that OsSAG12-2 codes for a functional protease that negatively regulates stress-induced cell death in rice. (Mus musculus) PubMed

 18115.

AGPL2 is associated with storage substance accumulation and subunit interactions in rice endosperm. (Mus musculus) PubMed

 18116.

OsHSD1 plays a specialized role in cuticle formation and lipid homeostasis. (Mus musculus) PubMed

 18117.

CyanoP is involved in the early steps of photosystem II assembly.[CyanoP] (Mus musculus) PubMed

 18118.

arginine phosphorylation by the McsB kinase is required and sufficient for the degradation of substrate proteins by Clp protease [McsB, ClpC, ClpP] (Mus musculus) PubMed

 18119.

Timely expression of BnaC.CP20.1 is necessary for tapetal degeneration and pollen wall formation. [BnaC.CP20.1] (Mus musculus) PubMed

 18120.

Results show that a loss of one axial ligand or the hydrogen bonding interaction with Tyr240 resulted in an increase in the redox potential of the heme for CgHmuT suggesting that the heme environmental structure stabilizes the ferric heme binding in CgHmuT, which will be responsible for efficient heme uptake under aerobic conditions where Corynebacteria grow. [HmuT] (Mus musculus) PubMed

 18121.

RNP-1 has roles in protecting microtubules and in directing cortical movement during cytokinesis and cell migration in Dictyostelium cells. [RNP-1] (Mus musculus) PubMed

 18122.

Study identified a new FIP protein, named FIP-dsq2, from Dichomitus squalens by sequence mining from the burgeoning genome databases. It seems to have an anti-tumor effect on human lung adenocarcinoma A549. [FIP-dsq2] (Mus musculus) PubMed

 18123.

Hd18 protein is involved in the control of flowering time.[Hd18] (Mus musculus) PubMed

 18124.

14-3-3 proteins, in conjunction with specific divalent cations, may stimulate TMKP1 activity.[TMPK1] (Mus musculus) PubMed

 18125.

Distinct features of RNA influence and ATPase efficiency between UAP56 and TcSub2 may reflect distinct structures for functional sites of TcSub2. For this reason, ligand-based or structure-based methodologies can be applied to investigate the potential of TcSub2 as a target for new drugs. (Mus musculus) PubMed

 18126.

SEP1 may regulate fruit ripening and softening of MF peaches, while this regulation may be lost in the non-melting flesh peaches.[SEP1] (Mus musculus) PubMed

 18127.

OsCPK4 is a potential molecular target to improve not only abiotic stress tolerance, but also blast disease resistance of rice crops. (Mus musculus) PubMed

 18128.

We reveal the interaction of RUPO with high-affinity potassium transporters. Phosphorylation of RUPO established and dephosphorylation abolished the interaction. These results have revealed the receptor-like kinase as a regulator of high-affinity potassium transporters via phosphorylation-dependent interaction (Mus musculus) PubMed

 18129.

These data suggest that Ago2 plays a crucial role in mediating the innate immune response of Aedes aegypti to Japanese encephalitis virus in a manner similar to that employed by dengue virus.[Ago2] (Mus musculus) PubMed

 18130.

Surprisingly, loss of either H3K9me3 or HP1 had only mild effects on heterochromatin compaction, whereas dim-3 caused more drastic changes, specifically decreasing interactions between constitutive heterochromatic domains (Mus musculus) PubMed

 18131.

Leptospira enolase also acts as an immune evasion protein by interacting with the negative complement regulators C4b binding protein and factor H.Enolase may facilitate leptospiral survival and dissemination, thus contributing to bacterial virulence [Enolase]. (Mus musculus) PubMed

 18132.

Study describes the successful purification and characterization in terms of both functional and structural aspects of a hyper thermostable esterase from Pyrococcus furiosus with predominantly beta-sheet structure and also a transesterification capacity. [Pf_Est] (Mus musculus) PubMed

 18133.

These results demonstrate that PA-X decreases the level of complement components, reactive oxygen species, cell death and inflammatory response, which may together contribute to the alleviated lung injury and the attenuation of the virulence of H5N1 virus in mice.[PA-X] (Mus musculus) PubMed

 18134.

CRL6 plays an important role in crown root development in rice via auxin-related signaling pathway.[CRL6] (Mus musculus) PubMed

 18135.

These results suggested that PbSUT2 affected sucrose content in sinks and the flowering phase during tomato plant growth and development.[PbSUT2] (Mus musculus) PubMed

 18136.

Comparison of catalytic properties of soluble invertase and cell wall invertase (CWI) has not shown any substantial difference between these two forms of the same enzyme. On the other side, CWI showed better thermal stability and stability in some of typical protein-denaturing agents. [invertase] (Mus musculus) PubMed

 18137.

A novel gene encoding DFA I-forming inulin fructotransferase (IFTase) from Streptomyces davawensis SK39.001 was cloned and characterized. [IFTase] (Mus musculus) PubMed

 18138.

These results highlight the important role of ZmNAC55 in positive regulates of drought resistence.[ZmNAC55] (Mus musculus) PubMed

 18139.

CpSK was a cold-adapted enzyme with a lower Km for its substrate shikimate. [CpSK] (Mus musculus) PubMed

 18140.

EG1 promotes floral robustness against temperature fluctuation by safeguarding the expression of floral identify genes through a high temperature-dependent mitochondrial lipid pathway [EXTRA GLUME1] (Mus musculus) PubMed

 18141.

Overall, these data suggest that Zip1 plays essential roles in zinc transport and the virulence of Cryptococcus neoformans.[Zip1] (Mus musculus) PubMed

 18142.

Taken together, the results demonstrate that dual phosphorylation sites of Hog1 of Candida albicans are crucial for white-opaque transition, sexual mating, and pheromone-induced cell adhesion.[Hog1] (Mus musculus) PubMed

 18143.

This study described the expression and regulation of Dps in E. coli in response to oxidative stress (Dps). (Mus musculus) PubMed

 18144.

ORF6 peptide is accumulated after infection in case of two isolates of Tobacco mosaic virus strain U1 (TMV-U1 common and TMV-U1 isolate A15). Unlike virus particles accumulating in the cytoplasm, the product of the ORF6 gene is found mainly in nuclei (Mus musculus) PubMed

 18145.

Results suggest that BLi03719 is an extracellular ribonuclease expressed in B. licheniformis under phosphate starvation conditions [BLi03719 ribonuclease]. (Mus musculus) PubMed

 18146.

This temporal shift of ZmCCA1-binding targets correlated with nonadditive and additive gene expression in early and late stages of seedling development. (Mus musculus) PubMed

 18147.

study showed novel functions of gene hshB in cell motility and biofilm formation by transcriptome analysis [hshB] (Mus musculus) PubMed

 18148.

This study evaluated the metabolic status of the bacteria impacts on the activity of NagB and the N-acetylglucosamine-6P-sensitive transcriptional repressor, NagC.[NagB; Nag C] (Mus musculus) PubMed

 18149.

WRKY62 is a positive defense regulator. WRKY62 positively regulated hypoxia genes, implying a role forWRKY62 in the modulation of the 'trade-off' between defense and hypoxia responses. [WRKY62] (Mus musculus) PubMed

 18150.

Study reports the crystal structure of MpaA. The asymmetric unit consists of two protein molecules and each monomer represents the common alpha/beta fold of metallocarboxypeptidases. The Tyr133-Asp143 loop appears to mediate the entrance and binding of the substrate into the active groove. [MpaA] (Mus musculus) PubMed

 18151.

these results suggest that Snapin, the pUL130 interacting protein, has a role in modulating HCMV DNA synthesis. (Mus musculus) PubMed

 18152.

hcmv-miR-US4-1 may involve in promoting cell apoptosis and benefiting discharge of infectious virus particles via down-regulation of QARS in HCMV-infected HELF cells. (Mus musculus) PubMed

 18153.

Results show that Pup adopts helical conformations under membrane mimetic and acidic conditions. Moreover, at low pH Pup, via both of its N- and C-terminal regions, binds to Mpa on sites from the N-terminal region in addition to the C-terminal region of the coiled-coil domain. [Pup] and [Mpa]. (Mus musculus) PubMed

 18154.

Y70's of CynD is playing an additional role necessary for CynD activity beyond influencing oligomerization.[CynD] (Mus musculus) PubMed

 18155.

Results report molecular cloning and characterization of AraA gene encoding a novel L-arabinose isomerase. The enzyme showed no substrate specificity toward D-galactose, and molecular docking results showed that the active site residues could only immobilize L-arabinose and recognized it as substrate for isomerization. [AraA] (Mus musculus) PubMed

 18156.

GhATAF1, the cotton stress-responsive NAC transcription factor, plays important roles in the response to both abiotic stress and biotic stress by coordinating the phytohormone signaling networks.[GhATAF1] (Mus musculus) PubMed

 18157.

The regulator of acetate metabolism RamA negatively regulates expression of a carbonic anhydrase bca in C. glutamicum. [RamA]; [bca] (Mus musculus) PubMed

 18158.

rgs-CaM displays a prevalent alpha-helical conformation and possesses three functional Ca2+-binding sites. [rgs-CaM] (Mus musculus) PubMed

 18159.

the global transcript profiles of the wild type (WT), Deltaflv1 and Deltaflv1/Deltaflv3 grown under constant light (GL) and fluctuating light, are reported.[Flv1, Flv3] (Mus musculus) PubMed

 18160.

PtHSP17.8 confers heat and salt tolerances in plants.[PtHSP17.8] (Mus musculus) PubMed

 18161.

bioinformatic analysis, real-time PCR, and luciferase assay validated that AK015322 serves as a decoy of microRNA-19b-3p (miR-19b-3p), antagonizes its function, and attenuates the repression of its endogenous target transcriptional factor Ets-variant 5 (ETV5) which was a pivotal gene for spermatogonial stem cell self-renewal (Mus musculus) PubMed

 18162.

TaH2A.7 can enhance drought tolerance via, at least in part, promoting stomatal closure, and appears to be a promising target for molecular breeding.[TaH2A.7] (Mus musculus) PubMed

 18163.

TaGAPC1 was induced inordinately by stresses in two wheat genotypes with contrasting drought tolerance.[TaGAPC1] (Mus musculus) PubMed

 18164.

OsPsbR1 may play key roles in photosynthesis and cold stress response and thus has the potential to improve cold stress tolerance of crops [PsbR1] (Mus musculus) PubMed

 18165.

overexpression of JrVHAG1 improves plant tolerance to osmotic stress relating to the abscissic acid signaling pathway.[JrVHAG1] (Mus musculus) PubMed

 18166.

PPR762 is an essential fertility restorer gene.[PPR762] (Mus musculus) PubMed

 18167.

An oxidative N-demethylase (HODM from Pseudomonas mendocina) reveals PAS transition from ubiquitous sensor to enzyme [HODM] (Mus musculus) PubMed

 18168.

study describes the production and purification of an Algerian S. aureus lipase; N-terminal sequence of the purified lipase, tentatively named SAL, was determined and compared to some staphylococcal lipases; the part of the gene encoding the mature lipase was cloned and sequenced [lipase] (Mus musculus) PubMed

 18169.

In this study, the authors have identified CagI, one of the type secretion system proteins, which interacted with CagA and played an important role for CagA stability.[CagI, CagA] (Mus musculus) PubMed

 18170.

TabHLH1 gene plays critical roles in plant tolerance to osmotic stresses largely through an ABA-dependent pathway.[TabHLH1] (Mus musculus) PubMed

 18171.

characterization of the binding affinity profile to different cell wall polysaccharides of the putative carbohydrate-binding-module of alpha-L-arabinofuranosidase 1 from Fragaria x ananassa, is reported.[FaARA1] (Mus musculus) PubMed

 18172.

NPC1 modulates silicon distribution and secondary cell wall deposition in nodes and grains, affecting mechanical strength and seed shattering. [NPC1 (non-specific phospholipase c1] (Mus musculus) PubMed

 18173.

Two cleavage fragments of NS80 function differently in the viral life cycle. (Mus musculus) PubMed

 18174.

These findings demonstrate that Vfr modulates the expression of several key traits and the production of important antibiotics involved in the biocontrol potential of Pseudomonas fluorescens FD6.[Vfr] (Mus musculus) PubMed

 18175.

OsWRKY51 is a positive transcriptional regulator of defense signaling.[OsWRKY51] (Mus musculus) PubMed

 18176.

The results suggest that Dbl2 is a novel regulator of Fbh1 and thereby Rad51-dependent DSB repair required for proper meiotic chromosome segregation and viable sex cell formation. [Dbl2] (Mus musculus) PubMed

 18177.

Overall, the results demonstrated an essential role of Orn in the expression of T3SS as well as pathogenesis of Pseudomonas aeruginosa.[Orn] (Mus musculus) PubMed

 18178.

The solution structure FerA derived from small angle X-ray scattering (SAXS) matched the dimer assembly predicted from the crystal structure. (Mus musculus) PubMed

 18179.

Expression of several abiotic stress-related genes like those coding for CBF/DREB, LEA, and WRKY factors was altered in transgenic lines indicating that MusaNAC042 is an efficient modulator of abiotic stress response in banana.[MusaNAC042] (Mus musculus) PubMed

 18180.

Findings indicate a functional NF-E2-related factor 2 (Nrf2)/kelch-like ECH-associated protein 1 (Keap1) pathway in bivalves: [Nrf2] (Mus musculus) PubMed

 18181.

Molecular cloning, characterization and expression of WAG-2 alternative splicing transcripts in developing spikes of Aegilops tauschii has been described. [WAG-2] (Mus musculus) PubMed

 18182.

The data suggest a role for cyAbrB2 in adjusting primary carbon and nitrogen metabolism to photosynthetic activity under fluctuating environmental conditions.[CyAbrB2] (Mus musculus) PubMed

 18183.

Subcellular fractionation analysis gave the evidence that EseG was specifically localized in the membrane fraction of infected host cells.[EseG] (Mus musculus) PubMed

 18184.

ZmSEC14p plays an important role in plant tolerance to cold stress.[ZmSEC14p] (Mus musculus) PubMed

 18185.

transgenic yeast cells over-expressing Cys-substituted yPrxII showed greater tolerance against heat and oxidative stress compared to WT-yPrxII.[PrxII] (Mus musculus) PubMed

 18186.

the function of the rice NFR5/NFP ortholog, OsNFR5/OsRLK2, as a possible candidate of the OsCERK1 partner for symbiotic signaling, was examined.[OsNFR5/OsRLK2] (Mus musculus) PubMed

 18187.

the capacity for starch synthesis in leaf sheath, which is controlled by CRCT, can indirectly affect the carbohydrate content, and then the photosynthetic rate in the leaf blade of rice grown under elevated carbon dioxide conditions.[CRCT] (Mus musculus) PubMed

 18188.

Thus, the obtained results show that the clpX gene was involved in the regulation of N-acyl-homoserine lactone production and a number of cellular processes in Burkholderia cenocepacia 370. (Mus musculus) PubMed

 18189.

CaAIP1 is a positive regulator of the osmotic stress tolerance mechanism.[CaAIP1] (Mus musculus) PubMed

 18190.

These results suggest that RbAp48 plays an important role in chromosome stability for proper organization of heterochromatin structure through the regulation of epigenetic mark. [RbAp48] (Mus musculus) PubMed

 18191.

This study demonstrated that the (p)ppGpp synthetases RelA and RelQ or (p)ppGpp can regulate the pathogenesis of this important zoonotic pathogen.[RelA, RelQ] (Mus musculus) PubMed

 18192.

OsCHX14 may play an important role in K(+) homeostasis during flowering in rice.[OsCHX14] (Mus musculus) PubMed

 18193.

The OsSNAT1 and OsSNAT2 transcripts were similarly suppressed in rice leaves during the melatonin induction after cadmium treatment. Phylogenetic analyses indicated that OsSNAT1 and OsSNAT2 are distantly related, suggesting that they evolved independently from Cyanobacteria prior to the endosymbiosis event. (Mus musculus) PubMed

 18194.

Results revealed a novel gene induced by salt stress with unknown functions. The gene was named as TaZNF.[TaZNF] (Mus musculus) PubMed

 18195.

This study reveals the negative role of OsERF109 in ethylene biosynthesis and drought tolerance in rice. (Mus musculus) PubMed

 18196.

This study represents the first report on biochemical properties of OsRad52-2a protein from important crop like rice.[OsRad52-2a] (Mus musculus) PubMed

 18197.

The cheA1 and cheA2 genes were both necessary for cell swarming, whereas the cheA3 gene product had a negative effect on the optimal swarming phenotype of Pseudomonas pseudoalcaligenes KF707 cells.[cheA1, cheA2, cheA3] (Mus musculus) PubMed

 18198.

Altogether, these data suggested that the Eha was required for the bacterial infection and the transcriptive regulation of the important virulence genes of Edwardsiella tarda.[Eha] (Mus musculus) PubMed

 18199.

Adh binds to OR5M11, which enhances Actinobacillus pleuropneumoniae pathogenicity by activating p38 which induces apoptosis of PAMs and IL-8 release [OR5M11] (Mus musculus) PubMed

 18200.

TlpD localisation is instructed by metabolic activity and protein interactions, and its sensory activity is linked to iron-sulfur cluster integrity [TlpD] (Mus musculus) PubMed

 18201.

P33 of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus is a functional homolog of P33 of Autographa californica nucleopolyhedrovirus. [P33] (Mus musculus) PubMed

 18202.

P33 of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus is a functional homolog of P33 of Autographa californica nucleopolyhedrovirus. [P33] (Mus musculus) PubMed

 18203.

H(+)-ATPase is involved in blue light-induced stomatal opening of dumbbell-shaped guard cells in monocotyledon species.[H+ ATPase] (Mus musculus) PubMed

 18204.

Study demonstrated that fadD19 and echA19 genes are not essential for viability. FadD19 is required in the initial step of the biodegradation of C-24 branched sterol side chains, but not those carrying a straight chain like cholesterol. Additionally, echA19 seems not essential in the degradation of either substrate. [fadD19] & [echA19] (Mus musculus) PubMed

 18205.

Adh binds to OR5M11, which enhances Actinobacillus pleuropneumoniae pathogenicity by activating p38 which induces apoptosis of PAMs and IL-8 release [Adh] (Mus musculus) PubMed

 18206.

Docking also discovered domains of the GOx protein that exhibit no interactions with the ligand or have even repulsive characteristics. The structural data clearly indicate some differences in the ligand PEI behavior bound at the two places/regions of glucose oxidase. (Mus musculus) PubMed

 18207.

Therefore, we conclude that afpab1 activity is correlated with susceptibility to oxidative stress, and deletion of afpab1 from A. fumigatus possibly leads to observed hypovirulence in an immunosuppressed mouse model. (Mus musculus) PubMed

 18208.

RsICE1 played an active role in improving rice cold tolerance.[RsICE1] (Mus musculus) PubMed

 18209.

apple MdJAZ2 was not only involved in the jasmonic acid response but also played roles in stress tolerance.[MdJAZ2] (Mus musculus) PubMed

 18210.

The results indicated that TC24 is a novel antimicrobial peptide against bacterial and viral pathogens, and that the observed effect of TC24 on bacterial RNA adds new insights to the action mechanism of fish antimicrobial peptides. Moreover, TC24 may play an important role in fighting pathogenic infection in aquaculture.[TC24] (Mus musculus) PubMed

 18211.

OsRab6a plays an important role in the regulation of Fe acquisition in rice plants.[OsRab6a] (Mus musculus) PubMed

 18212.

Most of the variation in the ability of human apo-hLf to kill Streptococcus pneumoniae is dependent on the variation in the binding of apo-hLf to surface PspA and this binding is dependent on variation in PspA as well as variation in capsule which may enhance killing by reducing the binding of apo-hLf to PspA.[PspA] (Mus musculus) PubMed

 18213.

OsV5A and OsV5B interact with two rice protochlorophyllide oxidoreductase (OsPORA and OsPORB) inside chloroplasts and they stabilize OsPORB in vitro under oxidative stress.[OsPORA, OsPORB, OsV5A, OsV5B] (Mus musculus) PubMed

 18214.

both PDH45 and SUV3 transgenic rice lines present decreased levels of necrosis/apoptosis as compared to wild type plants.[PDH45] (Mus musculus) PubMed

 18215.

We created an insertion mutation in comA gene homolog of R. solanacearum F1C1 strain.Our findings in this work indicate that an R. solanacearum strain inefficient in undergoing natural transformation can, however, be proficient in exhibiting twitching motility [comA]. (Mus musculus) PubMed

 18216.

TabHLH1 plays an important role in mediating adaptation to the phosphorus (Pi)- and nitrogen (N)-starvation stresses through transcriptional regulation of a set of genes that mediate the taken up of Pi and N and the cellular homeostasis of reactive oxygen species initiated by the nutrient stresses.[bHLH1] (Mus musculus) PubMed

 18217.

Using murine and pig infection models, the authors demonstrated for the first time that the formate-tetrahydrofolate ligase (fhs) is required for the full virulence of Streptococcus suis serotype 2.[fhs] (Mus musculus) PubMed

 18218.

the physiological function of ZmZIP7 which encodes a ZIP family transporter was characterized.[ZmZIP7] (Mus musculus) PubMed

 18219.

Ncr0700 is required for photomixotrophic growth and the regulation of glycogen accumulation.[Ncr0700] (Mus musculus) PubMed

 18220.

TaNAC69-1 is a transcriptional repressor of TaSHY2 and TaIAA7.[TaNAC69-1, TaSHY2, TaIAA7] (Mus musculus) PubMed

 18221.

Ascorbiac acid regeneration via enhanced DHAR activity modulates the ascorbate-glutathione cycle activity in C. reinhardtii against photo-oxidative stress.[DHAR1] (Mus musculus) PubMed

 18222.

distribution of CHS in grapevine was organ-specific and tissue-specific.[CHS] (Mus musculus) PubMed

 18223.

These findings indicate that the mould specific M46 gene is not necessary nor essential for dimorphism, maintaining the normal mould morphology, and growth rate of Histoplasma capsulatum.[M46] (Mus musculus) PubMed

 18224.

These data suggest that Histoplasma capsulatum Zrt2 is a vital part of zinc homeostasis and essential for the pathogenesis of histoplasmosis.[Zrt2] (Mus musculus) PubMed

 18225.

WSL3 affects rice cuticular wax production.[WSL3] (Mus musculus) PubMed

 18226.

The data demonstrated that CalR is a repressor of the tdh2 transcription and thereby inhibits the hemolytic activity of V. parahaemolyticus. (Mus musculus) PubMed

 18227.

Genes involved in pathogen resistance were constitutively up-regulated in OsABCG31-compromised plants, thus being a possible cause of the resistance to M. oryzae and the dwarf growth phenotype.[ABCG31] (Mus musculus) PubMed

 18228.

Pectin methyl esterase role in tolerant and susceptible wheats in response to Fusarium graminearum infection.[Pectin methyl esterase] (Mus musculus) PubMed

 18229.

The identified hits could serve as a base for further drug development against LuxP of Vibrio harveyi (Mus musculus) PubMed

 18230.

The rab3A regulates peripheral spindle and cortical granule (CG) migration, polarity establishment, and asymmetric division. [rab3a] (Mus musculus) PubMed

 18231.

Data revealed that specific amino acid substitutions in the Ebola virus GP have increased tropism for human cells, while reducing tropism for bat cells. [GP] (Mus musculus) PubMed

 18232.

Study of nonsynonymous mutation, Ebola virus (EBOV) glycoprotein (GP) mutant A82V, for its effect on viral infectivity; mutation, located at the NPC1-binding site on EBOV GP, occurred early in the 2013-2016 outbreak and rose to high frequency; found that GP-A82V had heightened ability to infect primate cells, including human dendritic cells. [GP] (Mus musculus) PubMed

 18233.

The H. pylori vacA c1 genotype might be one of the strongest risk predictors of gastric cancer in male patients aged >/=55 in Iran (vacA). (Mus musculus) PubMed

 18234.

Raa7 is a component of a multimeric complex that is required for trans-splicing of the second intron of psaA. [Raa7] (Mus musculus) PubMed

 18235.

Tox-1 is a pH- and temperature-tolerant mini-cellulose. [tox-1] (Mus musculus) PubMed

 18236.

these data show that intercellular communication via ESX-1 controls the expression of its evolutionary progenitor, ESX-4, to promote conjugation between mycobacteria. [ESX-1 and ESX-4] (Mus musculus) PubMed

 18237.

These findings have shown that PknL plays an important role in sensing the host environment and adapting itself in slowing down the growth of the pathogen and persisting within the host.[PknL] (Mus musculus) PubMed

 18238.

The authors show that mutations in either flmA or flmB genes of Azospirillum brasilense resulted in non-motile cells due to alterations in the polar flagellum assembly. Moreover, these mutations also affected the capability of Azospirillum brasilense cells to adsorb to maize roots and to produce LPS and EPS.[flmA, flmB] (Mus musculus) PubMed

 18239.

This result indicates that GlMBP1 (GL50803_8405) is a component of the Giardia lamblia cytoskeleton.[GlMBP1] (Mus musculus) PubMed

 18240.

Study reports the ATPase activity and crystal structure of a previously uncharacterized mycobacterial AAA protein, Msm0858. Msm0858 consists of an N-terminal beta-barrel domain and two AAA domains, each with ADP bound in the active site. Msm0858 is a structural homolog of mammalian p97, with respect to the linear order and tertiary structures of their domains. [Msm0858] (Mus musculus) PubMed

 18241.

Opacity protein OpaI of Neisseria gonorrhoeae in lipooligosaccharide mutants lost ability to interact with neutrophil-restricted CEACAM3. [OpaI] (Mus musculus) PubMed

 18242.

An expression study of the sesquiterpene cyclase genes present in the Botrytis cinerea genome, under culture conditions, is reported. [sesquiterpene cyclase] (Mus musculus) PubMed

 18243.

Results show that temperature-induced change in secondary structure of CotA protein was elucidated as probable reason its thermostability.The structural analysis using in silico approaches reveals 12 alpha-helices, 30 beta-sheets, nine turns, 31 random coils, and one conserved disulfide bond that probably plays an important role in the stability of protein. [CotA] (Mus musculus) PubMed

 18244.

This study reports the crystal structures of vacuolar soluble pyrophosphatases (VSP1s) from Trypanosoma cruzi and T. brucei, together with that of the T. cruzi protein bound to a bisphosphonate inhibitor. [Vacuolar Soluble Pyrophosphatase] (Mus musculus) PubMed

 18245.

This study reports the crystal structures of vacuolar soluble pyrophosphatases (VSP1s) from Trypanosoma cruzi and T. brucei, together with that of the T. cruzi protein bound to a bisphosphonate inhibitor. [Vacuolar Soluble Pyrophosphatase] (Mus musculus) PubMed

 18246.

cryo-electron microscopy structure of a full-length Slo1 channel from Aplysia californica in the presence of Ca(2+) and Mg(2+) at a resolution of 3.5 A [Slo1] (Mus musculus) PubMed

 18247.

structural basis for gating the high-conductance Ca(2+)-activated K(+) channel, Slo1, from Aplysia californica [Slo1] (Mus musculus) PubMed

 18248.

crystal structures of ISWI from the thermophilic yeast Myceliophthora thermophila and its complex with a histone H4 peptide [ISWI] (Mus musculus) PubMed

 18249.

Data indicate that phosphatase 2C clade A protein OsPP2C51 can dephosphorylates basic leucine zipper transcription factor OsbZIP10: [OsbZIP10] (Mus musculus) PubMed

 18250.

Identification and characterization of a semi-dwarfing gene ds-3 encoding a mutant DELLA protein regulating plant height through gibberellin signaling pathway [ds-3] (Mus musculus) PubMed

 18251.

Data indicate the differences in requirements of DNA-binding protein Teb1p and telomere-binding protein Taz1p for DNA binding: [Teb1] (Mus musculus) PubMed

 18252.

ERG11 mutations could be implicated in fluconazole resistance in C. neoformans. The ERG11 sequence in 11 clinical isolates with fluconazole MIC values >/=16mug/ml revealed an amino-acid-substitution G1855A mutation in 3 isolates from fluconazole-treated patients.This mutation would not affect susceptibility to itraconazole and voriconazole. ERG11. (Mus musculus) PubMed

 18253.

qFS07.1 controlling fiber strength was fine-mapped to a 62.6-kb region containing four annotated genes; a leucine-rich repeat protein kinase is the most likely candidate [LKK RLK] (Mus musculus) PubMed

 18254.

ROP6 is involved in root hair development as well as root hair deformation responses induced by Nod factors in the early stage of symbiotic interaction in L. japonicus.[ROP6] (Mus musculus) PubMed

 18255.

results indicate that SPDT functions in the rice node as a switch to allocate phosphorus preferentially to the grains; this finding provides a potential strategy to reduce the removal of phosphorus from the field and lower the risk of eutrophication of waterways [SPDT] (Mus musculus) PubMed

 18256.

the results of the present study demonstrated that miR4235p mediated H2O2induced apoptosis in the cardiomyocytes. Silencing of miR4235p significantly protected the cardiomyocytes from H2O2induced apoptosis (Mus musculus) PubMed

 18257.

we performed structure-based virtual screening using chemical libraries such as Binding, TOSLab and Maybridge to identify small molecule inhibitors of WbpP with better drug-like properties (Mus musculus) PubMed

 18258.

cloned sirtuin gene sirA; enzymatic characterization revealed the intrinsic NAD(+)-dependent deacetylation activity of SirA is comparable to human SIRT1; identified one of the target proteins as the 30S ribosomal protein S4 (rpsD product) [rpsD, sirA] (Mus musculus) PubMed

 18259.

These data indicated that alpha7-nAChR caused the inhibition of ASPinduced activation of p38 kinase and NFkappa B to inhibit the production of MCP1 and keratinocytederived chemokine. [keratinocytederived chemokine] (Mus musculus) PubMed

 18260.

Study provides evidence that GntR is involved in the cytotoxicity, virulence and intracellular survival of Brucella abortus during its infection. [GntR] (Mus musculus) PubMed

 18261.

The 3D model fits well into the experimentally retrieved low-resolution SAXS-based envelope of the enzyme, confirming monomeric state of SdBgl1B in solution.[Bgl1b] (Mus musculus) PubMed

 18262.

The active form of PerR reacts with dioxygen, which leads ultimately to disruption of the PerR/DNA complex and is thus physiologically meaningful. [PerR] (Mus musculus) PubMed

 18263.

HOTAIR is involved in the upregulation of matrix metalloproteinases induced by IL-1beta in temporomandibular joint osteoarthritis (TMJ OA) and possibly contribute to the development of TMJ OA through regulating apoptosis in chondrocytes (HOT AIR). (Mus musculus) PubMed

 18264.

Heterozygous mapkk4/+ mutant plants exhibited growth retardation, chlorosis symptoms and significantly reduced numbers of infection threads and nodules.[MtMAPKK4] (Mus musculus) PubMed

 18265.

These results emphasize the importance of HK1 gene duplication in poplar adaptation to drought stress[HK1]. (Mus musculus) PubMed

 18266.

Study demonstrates that phosphorylation of the receiver domain is essential for both functions of Rrp2, the function as a bEBP to activate sigma 54-dependent gene transcription and the function required for cell growth. [Rrp2] (Mus musculus) PubMed

 18267.

The expression of EhCP112 and EhADH is co-regulated and confirmed that the EhCPADH complex plays an important role in E. histolytica virulence. [EhCP112; EhADH] (Mus musculus) PubMed

 18268.

The results suggest that in fruits other than tomato the bulk of any gluconeogenic flux proceeds via PEPCK, whereas in tomato both PEPCK and PPDK could potentially be utilised. Further, the results indicate that the conversion of pyruvate/acetyl-CoA to malate by the glyoxylate cycle, for which ICL is necessary, is not a major pathway utilised by gluconeogenesis in fruits under normal conditions of growth.[PEPCK, PPDK, IC (Mus musculus) PubMed

 18269.

The CpxR/CpxA system is one of the second layers of envelope stress response that allows adaptation to high Fe(3+) conditions in this bacterium [CpxR]. (Mus musculus) PubMed

 18270.

Although CgAM forms a dimer without NaCl, it exists as a monomer in physiological concentration of NaCl. [CgAM] (Mus musculus) PubMed

 18271.

RLS3 gene plays key roles in sustaining the normal growth of rice, while loss of function in RLS3 leads to rapid leaf senescence.[RLS3] (Mus musculus) PubMed

 18272.

ZmAGO1a might be an important AGO1 ortholog in maize. The results presented provide further insight into the function of ZmAGO1a.[ZmAGO1a] (Mus musculus) PubMed

 18273.

Serum KatA antibodies are associated with gastric cancer risk and KatA may serve as a biomarker for gastric cancer. (Mus musculus) PubMed

 18274.

identification, expression, and functional characterization of a new glucuronoyl esterase (GE), NcGE, from the filamentous fungus Neurospora crassa. Based on the alignment of NcGE with other GEs so far characterized, propose novel consensus sequences for GEs containing the catalytic triad [NcGE]. (Mus musculus) PubMed

 18275.

Serum AhpC antibodies are associated with gastric cancer risk. (Mus musculus) PubMed

 18276.

The sequences of all samples were aligned with HCV subtype reference sequences (NS5B region) using the ClustalW multiple sequence alignment tool included in the Molecular Evolutionary Genetics Analysis (MEGA) v5.0 software package (Mus musculus) PubMed

 18277.

role of the recognition helix of response regulator WalR from Bacillus anthracis in DNA binding and specificity [WalR] (Mus musculus) PubMed

 18278.

Findings suggest that the N and C-termini of alpha mating factor (MATalpha) pro-peptide need to be presented in a specific orientation for proper interaction with the cellular secretion machinery and for efficient protein secretion: [MATalpha] (Mus musculus) PubMed

 18279.

Data provide evidence that all three isoforms (NhaP1, 2, and 3)operate in concert, contributing to K(+) resistance of V. cholerae. [NhaP1, 2, and 3] (Mus musculus) PubMed

 18280.

OscZOG1 was preferentially expressed in shoot and root meristematic tissues and nascent organs.[OscZOG1] (Mus musculus) PubMed

 18281.

The role of plant tyrosyl-DNA phosphodiesterase 1alpha in genome stability is studied using a Medicago truncatula MtTdp1alpha-depleted line.[MtTdp1alpha] (Mus musculus) PubMed

 18282.

HDTF1 is a negative regulator of the jasmonic acid (JA) pathway, and resistance to V. dahliae and B. cinerea can be engineered by activation of JA signaling. [HDTF1] (Mus musculus) PubMed

 18283.

MdSUT2 in apple is a homolog of the Arabidopsis vacuolar sucrose transporter AtSUT2. Ectopic expression of MdSUT2 in Arabidopsis decreased sucrose sensitivity in germination and seeding stage and increased sucrose transport activity. In addition, our results showed that MdSUT2 impacted on plant growth by accelerating vegetative growth and promoting early flowering in Arabidopsis. (SUT2) (Mus musculus) PubMed

 18284.

The reaction yield was successfully increased obtaining 100% product after a second treatment of the product solution with fresh immobilised chemically glycosylated-Candida antarctica B lipase . (Mus musculus) PubMed

 18285.

Taken all together, Helicobacter pylori toxin Tip-alpha might activate NF-kappaB to promote inflammation and carcinogenesis by inhibiting miR-3178 expression, which directly targets TRAF3, during Helicobacter pylori infection in gastric mucosal epithelial cells. (Mus musculus) PubMed

 18286.

ESA_RS09200 in C. sakazakii BAA894 encodes a phosphoethanolamine (PEA) transferase that specifically adds a PEA to the 4'-phosphate residue of lipid A (ESA_RS09200) (Mus musculus) PubMed

 18287.

PrtP was a member of serine proteinases, and played main roles in bacterial growth. [PrtP] (Mus musculus) PubMed

 18288.

These results suggest that OsSIDP366 may function as a regulator of theprocessing bodies (PBs) and stress granules and positively regulate salt and drought resistance in rice.[OsSIDP366] (Mus musculus) PubMed

 18289.

structural dynamics of Leishmania braziliensis Hsp90 molecular chaperone [HSP90] (Mus musculus) PubMed

 18290.

cloning, expression and characterization of the gene NcSRS67 [SRS67 (Mus musculus) PubMed

 18291.

The type I interferons (IFNs) LcIFNd and LcIFNh were found to be rapidly induced in head kidney and spleen by mixed bacteria of Vibrio alginolyticus, V. parahaemolyticus, and Aeromonas hydrophila. In head kidney primary cells, expression of these two LcIFN genes was increased by peptidoglycan from Bacillus subtilis and lipopolysaccharide from Escherichia coli.[IFNd, IFNh] (Mus musculus) PubMed

 18292.

These findings revealed that the ActS/ActR system is a key redox regulator in Sinorhizobium meliloti and provides a new cue to understanding Rhizobium-legume symbiosis.[ActS, ActR] (Mus musculus) PubMed

 18293.

Data suggest that the most significant biological effect of VacA activity on host cells leading to apoptosis is formation of membrane pores and the induction of vacuole formation. [VaxA, vacuolating cytotoxin A] [REVIEW] (Mus musculus) PubMed

 18294.

Overexpression of VviPrx31 decreased anthocyanin contents in Petunia hybrida petals under heat stress condition.[VviPrx31] (Mus musculus) PubMed

 18295.

TaMYB72 may function through up-regulation of florigen genes Hd3a and RFT1.[TaMYB72] (Mus musculus) PubMed

 18296.

APX1/2 plants were able to trigger alternative oxidative and antioxidant mechanisms involving signaling by Hydrogen peroxide.[APX1, APX2] (Mus musculus) PubMed

 18297.

The two S proteins of transmissible gastroenteritis virus and porcine epidemic diarrhea virus, indicating that SL7207 (pVAXD-PS1-TS) is a candidate oral vaccine for TGE and PED. (Mus musculus) PubMed

 18298.

The results of this study suggest that DprA has a significant effect on virulence characteristics of Streptococcus pneumoniae by influencing the expression of choline-binding protein and PsaA.[DprA] (Mus musculus) PubMed

 18299.

CLE-RS3 is a new component of autoregulation of nodulation in L. japonicas.[CLE-RS3] (Mus musculus) PubMed

 18300.

This study attempted to elucidate the role of a rice mitochondrial isoform (GPX1) in photosynthesis under normal growth and salinity conditions.[GPX1] (Mus musculus) PubMed

 18301.

initial activity after 13 consecutive reaction cycles or after 12 month of storage at 4 degrees C. The specific rate (rflow), enantiomer selectivity (E) and enantiomeric excess (ee) achievable with the best immobilized CaLB preparations were studied as a function of temperature in kinetic resolution of rac-1 performed in continuous-flow packed-bed bioreactors. (Mus musculus) PubMed

 18302.

OsCYO1 is enzymatically equivalent to AtCYO1 but that the physiological role of OsCYO1 in monocotyledonous plants may differ from that of AtCYO1 in dicotyledonous plants.[OsCYO1] (Mus musculus) PubMed

 18303.

WhmD can promote the assembly of FtsZ and indicated that WhmD may play a role in the division of M. smegmatis cells by assisting the polymerization of FtsZ [WhmD][FtsZ] (Mus musculus) PubMed

 18304.

this modified CALB not only has a strong anion exchange nature, while maintaining the activity, but it also shows improved stability under diverse reaction conditions without affecting the reversibility of the immobilization. (Mus musculus) PubMed

 18305.

This study explores the behavior of GumK toward its donor substrate uridine diphosphate - glucuronic acid. Turbidity measurements revealed that the interaction of GumK with uridine diphosphate - glucuronic acid produces aggregation of protein molecules under specific conditions. [GumK] (Mus musculus) PubMed

 18306.

Data suggest that the phenotype of the receptor like kinase CR4 (CRINKLY4) deletion mutant in moss provides insight into the role of the ancestral CR4 gene as a regulator of development in early land plants: [ CRINKLY4 (CR4)] (Mus musculus) PubMed

 18307.

The NRL2 protein interacted with Rolling-leaf (RL14), causing the leaves of the nrl2 mutants to have a higher cellulose content and lower lignin content than the WT, which may have been related to sclerenchymatous cell differentiation and tapetum degeneration.[NRL2] (Mus musculus) PubMed

 18308.

a Chlamydomonas mutant lacking Proton Gradient Regulation5 (PGR5) capable of producing hydrogen (H2 ) for 25 days with more than 30-fold yield increase compared to wild type, was identified.[PGR5] (Mus musculus) PubMed

 18309.

Transgenic rice plants expressing the vegetative insecticidal protein (Vip) showed considerable resistance against leaf folders and stem borersshowed: [Vip] (Mus musculus) PubMed

 18310.

Double-stranded RNA (dsRNA) molecules from Tobacco mosaic virus (TMV) p126 and coat protein (CP) genes confers significant resistance against TMV infection in Nicotiana tabacum cv. Xanthi plants: [p126] (Mus musculus) PubMed

 18311.

atrial fibrillation -induced up-regulation of miR-21 was negatively correlated with Smad7 expression; Down-expression of miR-21 ameliorates myocardial fibrosis in vivo [mirn21] (Mus musculus) PubMed

 18312.

Cytosolic pyruvate kinase GhPK6 is preferentially expressed in the late stage of fiber elongation process: [PK6] (Mus musculus) PubMed

 18313.

the core and nonstructural protein 5B sequences were amplified, and phylogenetic analysis was performed to determine the association between HCV subtypes and transmission routes.Phylogenetic analysis revealed that the two predominant subtypes of HCV, 2a and 6a, were primarily focused in four homologous clusters. (Mus musculus) PubMed

 18314.

Atypical enteropathogenic Escherichia coli-positive diarrheal stool samples containing the efa1/lifA gene had significantly higher bacterial loads than samples lacking this gene supporting the idea that efa1/lifA contributes to diarrheal pathogenesis.[efa1, lifA] (Mus musculus) PubMed

 18315.

study demonstrates that L. plantarum Pyruvate dehydrogenase subunit beta (PDHB) is a collagen-binding adhesin and is involved in biofilm development[Pyruvate dehydrogenase subunit beta] (Mus musculus) PubMed

 18316.

Molecular dynamic study of the MlaC protein that transfers phospholipids from the outer to inner membrane to maintain such lipid asymmetry in the Mla pathway has been presented. [MlaC] (Mus musculus) PubMed

 18317.

Molecular dynamic study of the MlaC protein that transfers phospholipids from the outer to inner membrane to maintain such lipid asymmetry in the Mla pathway has been presented. [MlaC] (Mus musculus) PubMed

 18318.

This study presents the crystal structures of active site catalytic triad mutants D7A, D7N, and D98N of the VapC toxin in absence of antitoxin. In all structures, as well as in solution, VapC forms a dimer. [VapC] (Mus musculus) PubMed

 18319.

The results suggest that CitERF13 is potentially involved in suppressing photosynthesis through multiple pathways, for instance, inhibiting photochemical activity of photosynthesis, CO2 carboxylation capacity and chlorophyll metabolism. [CitERF13] (Mus musculus) PubMed

 18320.

as important autophagy genes, overexpression of MdATG3s can afford tolerance to multiple abiotic stresses at the cellular and whole-plant level. [MdATG3a and MdATG3b] (Mus musculus) PubMed

 18321.

Sbt1 is a single-copy gene in maize. Sbt1 is expressed exclusively in the endosperm of the maize kernel within a short developmental time frame; zmsbt2 concentrates at the pedicel in front of the endosperm basal transfer layer [sbt1; sbt2] (Mus musculus) PubMed

 18322.

recombinant mature SslA self-assembled into crystalline monolayers with lattices resembling the one of the wild-type SslA. The study identifies the central protein domain consisting of amino acids 341-925 self-sufficient for self-assembly. (Mus musculus) PubMed

 18323.

TEM-15 and PBP3 substitutions impose an additive effect on resistance to third-generation cephalosporins in both H. influenzae and H. parainfluenzae. [TEM-15], [PBP3] (Mus musculus) PubMed

 18324.

Determinants of resistance to commonly used antibiotics in fecal and urinary E. coli strains from Swedish infants and children below 2 years of age studied. Multivariate analysis showed that resistance to any antibiotic was significantly associated with carriage of genes encoding P fimbriae (papC) and aerobactin (iutA), and a phylogenetic group D origin. [papC] (Mus musculus) PubMed

 18325.

Tertiary and quaternary structures of 2-keto-3-deoxy-D-gluconate dehydrogenase KduD and its complex with NADH were determined at high resolution (approximately 1.6 A) by X-ray crystallography. [KduD] (Mus musculus) PubMed

 18326.

Acyl chain preference and inhibitor identification of Moraxella catarrhalis LpxA [LpxA] (Mus musculus) PubMed

 18327.

A. oryzae AdmB involved in the cell wall integrity without going through the MpkA pathway [AdmB] (Mus musculus) PubMed

 18328.

The recombinant polyphenol oxidase A-695-His showed kinetic properties on catechol higher than for known laccases, a very high thermal stability, and a strong resistance to NaCl, DMSO, and Tween-80, all properties that are required for specific, targeted industrial applications. [polyphenol oxidase A] (Mus musculus) PubMed

 18329.

These results suggest that the RpoS expression peak is linked to (p)ppGpp alarmone increase, leading to enhanced motility and chemotaxis, and possibly contributing to the mucosal escape response.[RpoS] (Mus musculus) PubMed

 18330.

CAT8 gene is one of the first identified genes specifically involved in regulation of xylose alcoholic fermentation in the natural xylose-fermenting yeast O. polymorpha [CAT8] (Mus musculus) PubMed

 18331.

Here, molecular dynamics simulations investigated how conformational changes are propagated within and between different regions of the lectin domain of FimH. The results suggest a so called "population shift" model whereby binding of the lectin domain to either the pilin domain or mannose locks the beta sheet in a rather twisted or flat conformation, stabilizing the low or the high affinity state, respectively. [FimH] (Mus musculus) PubMed

 18332.

Results show that Sdps has higher affinity for decarboxylated S-adenosylmethionine than for putrescine (dcSAM). 3D structural model revealed that most of the ligand binding residues are identical to those of human and parasite Spds. The highly conserved acidic residues, Asp89, Asp159 and Asp162, are involved in the binding of putrescine and dcSAM and Pro166 seems to confer substrate specificity towards putrescine. [Spds] (Mus musculus) PubMed

 18333.

Findings contribute to a better understanding of specific host-pathogen interactions, showing that SadP1 contributes to the adhesion and translocation across host intestinal epithelium cells. Different SadP variants might contribute to differences in host restriction between Streoptococcus suis clones, due to differences in affinity and specificity of SadP receptors interactions. [SadP] (Mus musculus) PubMed

 18334.

The role of RGG1 in salinity stress tolerance (Mus musculus) PubMed

 18335.

A model is proposed in which a single GpsB hexamer can interact with multiple PBP1 molecules and can therefore influence the arrangement of PBP1 molecules within the cell division machinery, a dynamic multiprotein complex called the divisome, consistent with a role for GpsB in modulating the synthesis of the cell wall. [GpsB], [PBP1] (Mus musculus) PubMed

 18336.

This study determined the solution structure of PWWP domain of TbTFIIS2-1 by NMR spectroscopy, which was the first solution structure of PWWP domain solved in trypanosomatid. [TbTFIIS2-1] (Mus musculus) PubMed

 18337.

YwaD was glycosylated, and its activity decreased after deglycosylation, which was similar to that of the aminopeptidase from B. subtilis strain zj016. YwaD was most active toward l-arginine-4-nitroanilide. Moreover, it exhibited high resistance to carbamide, which was not true for aminopeptidases from B. subtilis strains 168 and zj016, which could simplify the purification of YwaD. [YwaD] (Mus musculus) PubMed

 18338.

Isoamylase 1 is important for both the synthesis of amylopectin and for determining its internal structure. [ISA1] (Mus musculus) PubMed

 18339.

NblA binds to the N-terminus of beta-phycocyanin. [nbla] (Mus musculus) PubMed

 18340.

Being a member of the family 6 carboxylesterase, R-est6 hydrolyzed triglycerides, pNP esters of the small and the medium fatty acid chain esters and an aryl ester-phenyl acetate. However, R-est6 was also found to hydrolyze the long-chain fatty acid ester which had never been reported for the family 6 carboxylesterase. Additionally, R-est6 was stable and active in the different water-miscible organic solvents. [R-est6] (Mus musculus) PubMed

 18341.

The authors show that the envelope glycoprotein Gn of hantaviruses binds genomic RNA through its cytoplasmic tail.[Gn] (Mus musculus) PubMed

 18342.

The data demonstrated that intact, properly folded zinc fingers in the Gn protein cytoplasmic tail as well as the middle domain of the N protein (that includes aa residues 80-248) of Tula virus are essential for the interaction.[Gn] (Mus musculus) PubMed

 18343.

These findings indicate that the nonpathogenic Tula virus Gn protein regulates interferon induction but accomplishes this via unique interactions with cellular TBK1 complexes. (Mus musculus) PubMed

 18344.

The authors show that the envelope glycoprotein Gn of hantaviruses binds genomic RNA through its cytoplasmic tail.[Gn] (Mus musculus) PubMed

 18345.

The combined results of these experiments support targeting of N to the ERGIC prior to its movement to the Golgi compartment and the requirement of an intact ERGIC for viral replication and, thus, the possibility of virus factories in this region.(HTNV N) (Mus musculus) PubMed

 18346.

Report gold nanoparticle enhanced immuno-PCR for ultrasensitive detection of Hantaan virus nucleocapsid protein. (Mus musculus) PubMed

 18347.

These results suggest that Hantaan virus NP has a role to promote Golgi localization of Gc through a mechanism possibly mediated by the Gc cytoplasmic tail.[Gc] (Mus musculus) PubMed

 18348.

A 2.3-A resolution crystal structure of the CCHFV nucleoprotein, is reported.[Nucleoprotein] (Mus musculus) PubMed

 18349.

Crystals of the Crimean-Congo haemorrhagic fever virus nucleocapsid protein belonged to space group C2, with unit-cell parameters a = 150.38, b = 72.06, c = 101.23 A, beta = 110.70 degrees and two molecules in the asymmetric unit[nucleocapsid protein] (Mus musculus) PubMed

 18350.

These results show that antagonism of the interferon-beta promoter is mediated by the nucleoprotein of the Crimean-Congo hemorrhagic fever virus strain Hoti.[nucleoprotein] (Mus musculus) PubMed

 18351.

we show that the HptB pathway controls biofilm formation and motility by involving both HsbD and the anti-anti-sigma factor HsbA (Mus musculus) PubMed

 18352.

Examination of p11 mutants with deletions of two transmembrane domains (TM) revealed that both were required for generating granules and for inducing necrosis.[p11] (Mus musculus) PubMed

 18353.

Spirochaeta thermophila secretes seven glycoside hydrolases for plant biomass degradation that carry a carbohydrate-binding module 64 (CBM64) appended at the C-terminus. Presented is the first crystal structure of a CBM64 at 1.2 A resolution. [glycoside hydrolase] (Mus musculus) PubMed

 18354.

Defining the enzymatic pathway for polymorphic O-glycosylation of the pneumococcal serine-rich repeat protein PsrP. (Mus musculus) PubMed

 18355.

dTBP2 appears to have a potential role in the treatment of atopic dermatitis.[dTBP2] (Mus musculus) PubMed

 18356.

The work presented confirms the function of Npun_R4582 as a catalase and provides insights as to how cells reduce potentially lethal peroxide levels produced by photosynthesis.[Npun_R4582] (Mus musculus) PubMed

 18357.

The deletion of clbA, which abolished the production of colibactin, substantially hindered Klebsiella pneumoniae hypervirulence in the key pathogenic steps toward the development of meningitis.[clbA] (Mus musculus) PubMed

 18358.

Biochemical and molecular characterization of the isocitrate dehydrogenase with dual coenzyme specificity from the obligate methylotroph Methylobacillus flagellatus has been reported. [Isocitrate dehydrogenase] (Mus musculus) PubMed

 18359.

Quantification of the expression of bgl-A, bgl, and CspA and enzymatic characterization of beta-glucosidases from Shewanella sp. G5 has been reported. [bgl-A], bgl, [CspA] (Mus musculus) PubMed

 18360.

Crystal structures of ToxA-Y7F consistently show a closed active site, whereas structures of ToxA-Y7A consistently show an open active site, suggesting that the hydroxyl group of Tyr7 plays a role in opening and closing the active site during the multistep reaction. (Mus musculus) PubMed

 18361.

Together this work illuminates purine salvage in M. jannaschii and the critical role of a cysteine residue in maintaining active site conformation of adenine deaminase. [adenine deaminase ] (Mus musculus) PubMed

 18362.

NtrX crystal structure revealed that NtrX is a dimeric ATP binding protein without ATPase activity.A sequence recognized by NtrX is presented along with a negative feedback mechanism.[NtrX] (Mus musculus) PubMed

 18363.

The obtained results will reveal the drug resistance mechanism between BMS-605339 and the mutant NS3 proteases, and provide valuable clue for designing novel and more potent drugs to HCV NS3 protease. (Mus musculus) PubMed

 18364.

beta-1,4-mannanase, termed AoMan134A was identified and the enzymatic properties including heat, pH, solvent, detergent and metal-ion stabilities were characterized [AoMan134A] (Mus musculus) PubMed

 18365.

Nuclear localization of the CdTlo2 activation domain, facilitated naturally by the Tlo Mediator binding domain or artificially through an appended nuclear localization signal, is sufficient for the CdTlo2 overexpression phenotypes. A C. albicans med3 null mutant causes multiple defects including the inability to localize Tlo proteins to the nucleus and reduced virulence in a murine systemic infection model. (Mus musculus) PubMed

 18366.

Nit4 seems to be specific for 3-cyanoalanine, and the amount of ammonium derived from the enzymatic activity doubled in the presence of exogenously added asparaginase activity, which demonstrated that the Nit4 enzyme had both 3-cyanoalanine nitrilase and hydratase activities.[Nit4] (Mus musculus) PubMed

 18367.

Plasmodium falciparum SufS (PfSufS) and PfSufE mobilize sulfur in the first step of Fe-S cluster assembly and are exclusive localized to the apicoplast. The cysteine desulfurase activity of PfSufS is greatly enhanced by PfSufE. (Mus musculus) PubMed

 18368.

The authors show that DnaK binds to a site on the Vibrio cholerae chromosome 2 replication initiator (RctB) that promotes initiation by reducing the initiator's propensity to dimerize.[DnaK, RctB] (Mus musculus) PubMed

 18369.

OsPMEI28 functions as a critical structural modulator by regulating the degree of pectin methylesterification and that an impaired status of pectin methylesterification affects physiochemical properties of the cell wall components and causes abnormal cell extensibility in rice culm tissues. [OsPMEI28] (Mus musculus) PubMed

 18370.

Genome-wide expression analysis showed that GaaR is required for the expression of genes necessary to release GA from PGA and more complex pectins, to transport GA into the cell, and to induce the GA catabolic pathway. (Mus musculus) PubMed

 18371.

the levels of the expression of opuCA and betL genes increase after cold and freezing shock (opuCA and betL) (Mus musculus) PubMed

 18372.

The increased CyaA in the RseA mutant was correlated with an apparent increased stability of the extracellular toxin and increased production of CyaA-containing outer membrane vesicles.[CyaA, RseA] (Mus musculus) PubMed

 18373.

crystal structure analysis and MD simulation were performed for PAN in complex with an inhibitor, which was already reported to have a high compound potency for comparison. (Mus musculus) PubMed

 18374.

AdhA activity was shown to be essential for heterotrophic growth (Mus musculus) PubMed

 18375.

Structure of the thermophilic l-Arabinose isomerase from Geobacillus kaustophilus reveals metal-mediated intersubunit interactions for activity and thermostability. (Mus musculus) PubMed

 18376.

These findings identify YSS1 as a novel regulator of PEP activity essential for chloroplast development at rice seedling stage.[YSS1] (Mus musculus) PubMed

 18377.

thnR functions as a negative transcriptional regulator of thurincin H synthesis (thnR) (Mus musculus) PubMed

 18378.

LSG2 disrupts parental extracellular matrix cooperatively with VheA.[LSG2] (Mus musculus) PubMed

 18379.

Determined are the crystal structures of OprN and OprJ. These structures revealed several features, including tri-acylation of the N-terminal cysteine, a small pore in the beta-barrel domain, and a tightly sealed gate in the alpha-barrel domain. [OprN, OprJ] (Mus musculus) PubMed

 18380.

The study evaluated the role of NF-kappa B in ApxI-elicited production of inflammatory cytokines in pulmonary alveolar macrophages via the mitogen-activated protein kinases (MAPKs) p38 and cJun NH2-terminal kinase (JNK).[NF-kappa B] (Mus musculus) PubMed

 18381.

the full-length sequence of Paralichthys olivaceus pou5f3 (Popou5f3), was isolated and found to be homologous to mammalian Oct4.[Pou5f3] (Mus musculus) PubMed

 18382.

introduction of a mutation in zinc finger 1 of the ExoN domain of nsp14 led to production of a virus that induced a weak antiviral response, most likely due to the accumulation of lower levels of dsRNA in the late phases of infection; these observations allowed proposal of a novel role for Coronavirus nsp14 ExoN activity in counteracting the antiviral response (Mus musculus) PubMed

 18383.

This work shows the first crystal structures of a group II fructosyl amine oxidases, namely the free and the substrate-bound form of the isoenzyme Amadoriase I from Aspergillus fumigatus, both at high resolution. [Amadoriase I] (Mus musculus) PubMed

 18384.

A full-length receptor histidine kinase, RpfC, directly binds to a fatty acid-based signal factor using a short sensor region. This binding event stimulates RpfC autokinase activity by triggering conformational change in its catalytic region, which is critical in regulating bacterial quorum sensing and virulence. [Strain Xcc 8004] (Mus musculus) PubMed

 18385.

the putative radical SAM enzyme, MftC, oxidatively decarboxylates the C-terminus of the MftA peptide in the presence of the accessory protein MftB. (Mus musculus) PubMed

 18386.

N-glycosylation of beta2 subunits plays crucial roles in imparting functional heterogeneity of BK channels.[KCMB2] (Mus musculus) PubMed

 18387.

Results describe the functional features of Xanthomonas axonopodis sucrose hydrolase, a member of the newly defined carbohydrate utilization locus that regulates the utilization of plant sucrose in phytopathogenic bacteria [SUH]. (Mus musculus) PubMed

 18388.

XagR differentially modulates expression of a variety of genes during the infection process in response to feedback from plant molecules elaborated during infection to coordinate processes such as invasion, infection[XagR] (Mus musculus) PubMed

 18389.

yeast dynamin interacts with ESCRT II and III complexes, and it functions in Cps1 trafficking toward the vacuole. [Vps1] (Mus musculus) PubMed

 18390.

The results show that both DeltapdpC and DeltaiglG mutants of the live vaccine strain (LVS) of Francisella tularensis did not replicate within human monocyte-derived macrophages.[pdpC, iglG] (Mus musculus) PubMed

 18391.

GdpX1 attenuates motility, exopolysaccharide production and virulence. [Gdpx1] (Mus musculus) PubMed

 18392.

Significant scrapie-associated increase was repeatedly found for miR-342-3p and miR-21-5p. [ miR-342-3p ] (Mus musculus) PubMed

 18393.

Lc-IRAK4 could interact with MyD88, whereas MyD88-mediated NF-kappaB activation was significantly impaired when co-transfected the two in HEK 293T cells.[NF-kappaB] (Mus musculus) PubMed

 18394.

HAM-14 is a novel member of the HAM-5/MAK-2 pathway essential for germling fusion. HAM-14 interacts with MAK-2 and MEK-2. (Mus musculus) PubMed

 18395.

The gdpS modulates staphylococcal biofilm independently of c-di-GMP signaling pathway. Furthermore, mutations of the start codon did not abolish the capacity of gdpS to enhance biofilm formation. (Mus musculus) PubMed

 18396.

Mutational analysis of Tyr156 in the substrate-binding site of quinoprotein aldose sugar dehydrogenase from Thermus thermophilus HJ6 [ASD] (Mus musculus) PubMed

 18397.

In this study, confocal near-infrared resonance Raman spectroscopy along with hydrogen/deuterium exchange, retinal analogue substitution, and site-directed mutagenesis were used to study the retinal structure as well as its interactions with the protein in the unphotolyzed state of an Anion Channelrhodopsin from Guillardia theta (ACR1). [ACR1] (Mus musculus) PubMed

 18398.

a mutant, yellow leaf and dwarf 1 (yld1), which exhibited decreased plant height and premature leaf senescence, was identified.[yld1] (Mus musculus) PubMed

 18399.

This study reports the biochemical and structural characterization of M. smegmatis phosphoribosylpyrophosphate synthetase (PrsA), the ortholog of M. tuberculosis PrsA, the unique enzyme responsible for the synthesis of phosphoribosylpyrophosphate. [PrsA] (Mus musculus) PubMed

 18400.

Thus, Fhb is a multifunctional bacterial protein, which binds host complement component C3 as well as FH and interferes with innate immune recognition in a secret protein manner. S. suis 2 therefore appears to have developed a new strategy to combat host innate immunity and enhance survival in host blood. (Mus musculus) PubMed

 18401.

this study identified RNA polymerase II as a cellular target for both pM79 and pM92. [pM79 and pM92] (Mus musculus) PubMed

 18402.

DSG1 positively regulates cell division and elongation and may be involved in multiple hormone pathways. (Mus musculus) PubMed

 18403.

These results show that formate dehydrogenase has the capabilities to reduce nitrate and to oxidize formate at the same molybdenum site. [formate dehydrogenase] (Mus musculus) PubMed

 18404.

(Hippo) NF2 promotes Ischemia/Reperfusion injury by regulating Hippo signaling in the heart. (Mus musculus) PubMed

 18405.

we found that chronic corpus atrophic gastritis was non-significantly associated with an increased pancreatic cancer risk (OR = 1.35; 95% CI: 0.77, 2.37), and although based on small numbers, the excess risk was particularly marked among individuals seronegative for both H. pylori and CagA (OR = 5.66; 95% CI: 1.59, 20.19, p value for interaction < 0.01). (Mus musculus) PubMed

 18406.

Rev is translated from the tat-rev mRNA through leaky scanning of the tat CUG and deletion or attenuation of the Kozak sequence resulted in expression of an N-terminal 11 aa-truncated Rev in addition to wild-type Rev. (Mus musculus) PubMed

 18407.

a stress regulated cDNA encoding a dehydrin-like boiling stable protein (designated as wBsSRP; wheat boiling stable stress responsive protein) from drought stressed seedlings of drought tolerant cultivar of wheat, was identified.[wBsSRP] (Mus musculus) PubMed

 18408.

Thus, Marek's disease herpesvirus ICP27 gene expression is dependent on alternative promoters, the usage of which is regulated by DNA methylation, which differs between viral stages.[ICP27] (Mus musculus) PubMed

 18409.

These observations argue that an important role for miR-UL112-1 during latency is to ensure tight control of lytic viral immediate early (IE) gene expression thereby preventing recognition of latently infected cells by the host's potent pre-existing anti-viral cytotoxic T lymphocyte response.[miR-UL112-1] (Mus musculus) PubMed

 18410.

Structural and Functional Investigation of FdhC from Acinetobacter nosocomialis [FdhC] (Mus musculus) PubMed

 18411.

Study demonstrate that a mutation in a highly dynamic region of the intermediate domain of the AAA+ HslU hexamer plays a key role in controlling both the rate and direction of ATP-fueled degradation by the HslUV protease. [HslUV] (Mus musculus) PubMed

 18412.

Neutralization of the complement factor C3-dependent antichlamydial activity was dependent on the proteolytic activity of Chlamydia trachomatis CPAF and correlated with the CPAF-mediated degradation of complement factor C3 and factor B.[CPAF] (Mus musculus) PubMed

 18413.

The results indicate that these differences in 2-KPCC are key in discriminating between carbon dioxide and protons as attacking electrophiles (Mus musculus) PubMed

 18414.

(CD45) Mitral valve endothelial cells express CD45, both in vivo post myocardial infarction and in vitro. (Mus musculus) PubMed

 18415.

Results provide evidence that OsDOF18 mediates ammonium transport and nitrogen distribution, which then affects nitrogen use efficiency. [DOF18] (Mus musculus) PubMed

 18416.

the three-dimensional structures of two of the enzymes required for Kdo8N biosynthesis in S. oneidensis [KdnB][KdnA] (Mus musculus) PubMed

 18417.

A haplotype analysis identified favorable alleles of TAC3, D2 and TAC1, which may be used for breeding plants with an ideal architecture. In conclusion, there is a diverse genetic basis for tiller angle between the two subpopulations, and it is the novel gene TAC3 together with TAC1, D2, and other newly identified genes in this study that controls tiller angle in rice cultivars. (Mus musculus) PubMed

 18418.

Study demonstrates that bsrE/SR5 is a new type I TA system. The bsrE mRNA encodes a 30 aa hydrophobic toxin, and the 163 nt untranslated antisense RNA SR5 acts as antitoxin that neutralizes the toxin's effects. [bsrE and SR5] (Mus musculus) PubMed

 18419.

the Endo-S2 glycosynthase mutants were found to be much more active in general than the Endo-S mutants for transglycosylation (Mus musculus) PubMed

 18420.

we identified a nearby second CRM operating in inter-modular AND logic with the first CRM to control hox11/13b expression in hindgut endoderm. Our results suggest a mechanism for continuous gene expression in response to changing developmental network functions that depends on sequential combinatorial regulation of individual CRMs (Mus musculus) PubMed

 18421.

Crystal structures of H10 HA mutants with human and avian receptor analogs, receptor-binding studies, and tissue staining experiments illustrate the important role of the 150-loop in H10 receptor specificity. (Mus musculus) PubMed

 18422.

a novel yellow-green leaf gene YS83, was identified.[ys83] (Mus musculus) PubMed

 18423.

Results from this study showed that the U-box protein gene PUB quickly responded to both biotic stress and abiotic stress and significantly influenced the accumulation of resistance related proteins in grapevine.[VaPUB] (Mus musculus) PubMed

 18424.

This study conducted molecular dynamics simulations of Trypanosoma brucei RNA editing ligases REL1 and REL2 complexed with double-stranded RNA (dsRNA) fragments. [REL1, REL2] (Mus musculus) PubMed

 18425.

BnGA2ox6 regulates plant hight, silique development, flowering and chlorophyll accumulation in transgenic Arabidopsis.[BnGA2ox6] (Mus musculus) PubMed

 18426.

structure of Glucosamine/Glucosaminide N-Acetyltransferase [GlmA] (Mus musculus) PubMed

 18427.

Thus, defective interfering particle production by lymphocytic choriomeningitis virus may be dynamically regulated via phosphorylation of S41 in matrix protein Z.[matrix protein Z] (Mus musculus) PubMed

 18428.

The active GoxA was present as a homodimer with no detectable affinity for GoxB, whereas the precursor was isolated as a monomer in a tight complex with one GoxB. Thus, the interaction of GoxA with GoxB and subunit assembly of mature GoxA are each dependent on the extent of cysteine tryptophylquinone biosynthesis. [GoxA, GoxB] (Mus musculus) PubMed

 18429.

This study discovered that the degradation of a multidomain and multispan integral membrane protein AcrB could be facilitated by the introduction of a ssrA-tag at the C-terminus of the protein sequence and demonstrated that the cytoplasmic unfoldase-protease complex ClpXP was involved in the degradation. [AcrB] (Mus musculus) PubMed

 18430.

The structure pf MltF protein comprises two modules: an ABC-transporter-like regulatory module (RM) and a catalytic module. Its allosteric mechanism for the control of its catalytic activity results in a dramatic conformational transition that occurs following occupancy of its RM by peptidoglycan- derived effectors. [Mltf] (Mus musculus) PubMed

 18431.

Light and pH-induced Changes in Structure and Accessibility of Transmembrane Helix B and Its Immediate Environment in Channelrhodopsin-2. (Mus musculus) PubMed

 18432.

Results provide evidence that RcsR1, a small RNA (sRNA), is an ancient, stress-related riboregulator in rhizobia and propose that it links stress responses to quorum sensing in S. meliloti. Also, there is direct interaction between the 5'-UTR of sinI mRNA encoding the autoinducer synthase and the sRNA. [RcsR1, sinI] (Mus musculus) PubMed

 18433.

Based on these results, the authors conclude that decreased levels of trans-sialidase (TS), complement regulatory protein (CRP) and cruzipain (Czp) expression could contribute to loss of T. cruzi trypomastigote virulence.[TS, CRP, Czp] (Mus musculus) PubMed

 18434.

the C-terminal extension of M. truncatula GS2a is important for the activity of the enzyme and does not contain crucial information for the import process.[GS2a] (Mus musculus) PubMed

 18435.

characterization of a novel DyP-type peroxidase [DyP2] (Mus musculus) PubMed

 18436.

knockdown of GhNINJA represses the root growth and enhances the tolerance to V. dahliae. [GhNINJA] (Mus musculus) PubMed

 18437.

small cavities have an effect on allosteric inhibition of phosphofructokinase from Bacillus stearothermophilus [phosphofructokinase] (Mus musculus) PubMed

 18438.

These findings provide essential information regarding transcriptional regulatory mechanisms of StInvInh2 in cold-stored tubers contrasting cold-induced sweetening capacity.[ StInvInh2] (Mus musculus) PubMed

 18439.

combined results demonstrate that OxyR2 functions as a three-state redox switch to tightly regulate the expression of prx2, preventing futile production of Prx2 in cells exposed to high levels of H2O2 sufficient to inactivate Prx2. (Mus musculus) PubMed

 18440.

results suggest that TaSOS1-974 increases salt tolerance in transgenic plants by transporting Na+ out of plant cells more efficiently plants under saline conditions; growth of transgenic plants expressing TaSOS1-974 or TaSOS1 was better than non-transformed plants under normal conditions, suggesting that TaSOS1 may also be involved in regulation of plant growth [SOS1] (Mus musculus) PubMed

 18441.

results suggest that ZmCBL9 may interact with various CBL-interacting protein kinases (CIPKs) to regulate the abiotic stress and ABA response signaling in plants.[CBL9] (Mus musculus) PubMed

 18442.

results indicated that OsABCG26 plays an important role in anther cuticle and pollen exine formation and pollen-pistil interactions in rice[ABCG26] (Mus musculus) PubMed

 18443.

the molecular basis of the nana plant2 (na2) phenotype as a loss-of-function mutation in one of the two maize paralogs of the Arabidopsis (Arabidopsis thaliana) BR biosynthetic gene DWARF1 (DWF1), was identified.[na2] (Mus musculus) PubMed

 18444.

a homology model of the open-state cockroach sodium channel BgNav1-1a. (Mus musculus) PubMed

 18445.

Using Bacillus subtilis and its lytic phage SPP1, study shows that resistant (R) cells, lacking SPP1 receptor, can be lysed by SPP1 when co-cultured with sensitive (S) cells. Phage invasion into R cells was mediated, at least in part, by phage attachment molecules delivered from S to R cells, transiently turning R into "S" cells. [SPP1R] (Mus musculus) PubMed

 18446.

An 1,4-beta-endoglucanase from Aspergillus niger, AnCel5A, was expressed in Pichia pastoris.The recombinant AnCel5A shows outstanding pH and heat stability. Crystal structures of AnCel5A in apo- and substrate-bound form were solved. [AnCel5A] (Mus musculus) PubMed

 18447.

In conclusion the contribution of pUL74 is masked when the UL128 locus is expressed at high levels, and its role in cell-free virus spread is only revealed when expression of the pentameric complex is inhibited.[UL128] (Mus musculus) PubMed

 18448.

In the present work, we describe the crystal structure of TcG6PDH obtained in a ternary complex with the substrate beta-d-glucose-6-phosphate (G6P) and the reduced 'catalytic' cofactor NADPH, which reveals the molecular basis of substrate and cofactor recognition (Mus musculus) PubMed

 18449.

(COMP) Serum concentrations of COMP and CTX-II were significantly higher in the osteoarthritis group compared to controls. (Mus musculus) PubMed

 18450.

The N3 subdomain of FnBPB contains the full plasminogen-binding site, and this includes, at least in part, two conserved patches of surface-located lysine residues that were recognized by kringle 4 of the host protein. (Mus musculus) PubMed

 18451.

The NleB effector limited host IFN-beta production by inhibiting Lys(63)-linked ubiquitination of TNF receptor-associated factor 3 (TRAF3). Inhibition was dependent on the glycosyltransferase activity of NleB. (Mus musculus) PubMed

 18452.

The nickel-bound ACS-AcsFCh complex remains inactive until MgATP is added, thereby converting inactive to active ACS. AcsFCh is a MinD-type ATPase and belongs to the CooC protein family, which can be divided into homologous subgroups. We propose that proteins of one subgroup are responsible for assembling the Ni,Ni-[4Fe4S] cluster of ACS (Mus musculus) PubMed

 18453.

Protein Arginine Methyltransferase Product Specificity Is Mediated by Distinct Active-site Architectures. (Mus musculus) PubMed

 18454.

OsValRS2 plays an essential role in chloroplast development and regulating chloroplast ribosome biogenesis.[OsValRS2] (Mus musculus) PubMed

 18455.

PUB1 expression is activated during successive stages of root colonization by Rhizophagus irregularis that is compatible with its interaction with DOES NOT MAKE INFECTIONS 2.[PUB1, DMI2] (Mus musculus) PubMed

 18456.

Crystal structures of sialic acid- and galactose-binding HA-33 are broadly similar in appearance. However, small-angle X-ray scattering revealed distinct solution structures for HA-33/HA-17 trimers. A structural change in the C-terminal variable region of HA-33 might cause a dramatic shift in the conformation and sugar-recognition mode of HA-33/HA-17 trimer. [HA-33, HA-17] (Mus musculus) PubMed

 18457.

[HNF6] hepatic loss of HNF6 up-regulated many lipogenic genes bound directly by HNF6. (Mus musculus) PubMed

 18458.

PB2 is imported into mitochondria, where it localizes to the mitochondrial matrix and mitochondrial MAVS is not required for the import. (Mus musculus) PubMed

 18459.

these results uncover a novel function of CRK1 in anterograde protein trafficking and elucidate the mechanistic role of CRK1 in protein trafficking through regulation of the COPII subunit Sec31. (Mus musculus) PubMed

 18460.

The viral RNA polymerase binds directly to the serine-5-phosphorylated form of the host Pol II CTD, both in the presence and in the absence of viral RNA, and show that this interaction is conserved in evolutionarily distant influenza viruses [RNA polymerase]. (Mus musculus) PubMed

 18461.

The structure of VP90(71-415) is comprised of two domains: an S domain, which adopts the typical jelly-roll beta-barrel fold, and a P1 domain, which forms a squashed beta-barrel consisting of six antiparallel beta-strands similar to what was observed in the hepatitis E virus (HEV) capsid structure.[VP90] (Mus musculus) PubMed

 18462.

Partially purified protease was highly stable (100%) within pH range 7.0-12.0 and salinities of 0-5% NaCl for 48 hr. Cu(2+), Mn(2+), Co(2+), and Ca(2+) did not inhibit its activity. [protease] (Mus musculus) PubMed

 18463.

the role of the maturation protease encoded within the Hyd-5 operon, HydD, was found to be partially complemented by the maturation protease encoded in the Hyd-1 operon, HyaD. [Hyd-5] (Mus musculus) PubMed

 18464.

Complementary crystallographic and biophysical characterization of BspA reveal a novel beta-sandwich adhesion domain and unique asparagine-dependent super-helical stalk. Collectively, these findings establish a new bacterial adhesin structure that has in effect been hijacked by a pathogenic Streptococcus species (Mus musculus) PubMed

 18465.

This study establishes Sbg1p as a key member of a group of proteins that link the plasma membrane, the actomyosin ring, and the division septum assembly machinery in fission yeast. (Mus musculus) PubMed

 18466.

Using an integrated approach of structural, kinetic, and computational analysis, this study shows that the structurally constrained TrmD knot is required for its catalytic activity. [TrmD] (Mus musculus) PubMed

 18467.

Using electron cryomicroscopy, this study determined the structure of TcdA1 from Photorhabdus luminescens embedded in lipid nanodiscs. [TcdA1] (Mus musculus) PubMed

 18468.

The 2.9-A crystal structure of intact Cch shows that it forms a hexameric ring. Cch, like the archaeal and eukaryotic MCM-family replicative helicases, belongs to the pre-sensor II insert clade of AAA+ ATPases. [Cch] (Mus musculus) PubMed

 18469.

CYP260A1 exhibited an electrocatalytic activity detected by an increase of the reduction current in the presence of dissolved oxygen and upon addition of the substrate (androstenedione) in the air-saturated buffer. (Mus musculus) PubMed

 18470.

These results highlight a heme-independent mechanism for activation of V. cholerae H-NOX that implicates this protein as a dual redox/NO sensor (Mus musculus) PubMed

 18471.

The authors could demonstrate that HHV-6 efficiently integrated in the absence of U94 using a new quantitative integration assay.[U94] (Mus musculus) PubMed

 18472.

The impact of apteral females of bird cherry-oat aphid (Rhopalosiphum padi L.) and grain aphid (Sitobion avenae F.) feeding on expression levels of all four NADPH oxidase genes (rbohA, rbohB, rbohC, rbohD) and total activity of NADPH oxidase enzyme in maize plants were investigated. [rbohA, rbohB, rbohC, rbohD] (Mus musculus) PubMed

 18473.

Our structural analysis of these proteins revealed key differences among PA5088, PA5087, and their homologs. Our docking experiments have shed light on the putative interaction mechanism of their function as phospholipase D inhibitors. (Mus musculus) PubMed

 18474.

Based on our homology model of NorM_PS, variants with mutations of amino acids that are potentially involved in substrate binding, were constructed. By carrying out the functional characterization of these variants, the critical amino acid residues (Glu-257 and Asp-373) for high-affinity DAPI binding were determined. Taken together, our results suggest a new substrate-binding site for MATE transporters. (Mus musculus) PubMed

 18475.

Study reveals the recently solved structure of Thermotoga maritima Csm2 representing a dimer with the extensive structure swapping between monomers. [Csm2] (Mus musculus) PubMed

 18476.

SynEtr1 is a bifunctional receptor that mediates responses to both light and ethylene.[SynEtr1] (Mus musculus) PubMed

 18477.

These findings uncover a novel role for Lem2-Nur1 as a key functional link between localization at the nuclear periphery and heterochromatin-mediated gene silencing. (Mus musculus) PubMed

 18478.

These results reveal a molecular cascade in the rice antiviral pathway in which miR444 and its MADS box targets directly control OsRDR1 transcription.[miR444, OsRDR1] (Mus musculus) PubMed

 18479.

cocrystal structures of Sfm1 in complex with various ligands, are reported. [Sfm1] (Mus musculus) PubMed

 18480.

the bacterial MxSafC exhibits excellent regioselectivity for para as well as for meta methylation, depending on the substrate's characteristics.[MxSafC] (Mus musculus) PubMed

 18481.

Nnk1 regulates chronological lifespan through the regulation of ght5(+) and Nnk1 might coordinate glucose availability and lifespan in fission yeast.[Nnk1, ght5] (Mus musculus) PubMed

 18482.

These results suggest that MsrB has an important role in the intracellular replication of Francisella tularensis in macrophages and infection in mice.[MsrB] (Mus musculus) PubMed

 18483.

the crystal structure of the LpiR1 (Lpg0634) effector protein and investigate the effects of its overexpression in mammalian cells. LpiR1 is an alpha-helical protein that consists of two similar domains aligned in an antiparallel fashion. The hydrophilic cleft between the domains might serve as a binding site for a potential host cell interaction partner. LpiR1 binds the phosphate group at a conserved site (Mus musculus) PubMed

 18484.

Here are presented 3.5-A- and 3.9-A-resolution crystal structures of the HIV-1 env protein gp120 trimer with fully processed and native glycosylation, revealing a glycan shield of high-mannose and complex-type N-glycans, which were used to define complete epitopes of two broadly neutralizing antibodies. [env protein gp120] (Mus musculus) PubMed

 18485.

This approach is the first to determine the Michaelis-Menten parameters for a recombinant TAm (PpbauA) from Pseudomonas putida NBRC14164. The corresponding Vmax and KM values for both enantiomers of 2-amino-1-propanol and 2-amino-1-butanol were obtained, and the calculated kinetic E-factors of PpbauA toward 2-amino-1-propanol and 2-amino-1-butanol are 3 (S) and 6 (R), respectively. (Mus musculus) PubMed

 18486.

These data indicated that in addition to the GacA-RsmA system, GacA controls polymer synthesis and encystment by controlling the phosphorylation of the EIIA(Ntr), revealing a previously unrecognized link between GacA and PTS(Ntr).[GacA, EIIA(Ntr)] (Mus musculus) PubMed

 18487.

Infectious bronchitis virus does induce host shutoff, and the authors find that its accessory protein 5b is indispensable for this function.[5b] (Mus musculus) PubMed

 18488.

The RhtA gene is located in tandem with a hypothetical alpha-L-rhamnosidase gene (rhaB). Transcriptional analysis of rhtA and rhaB confirmed that both genes have a coordinated expression, being strongly and specifically induced by L-rhamnose, and controlled by RhaR, a transcriptional regulator involved in the release and catabolism of the methyl-pentose. (Mus musculus) PubMed

 18489.

results represent the first reconstitution of the proteolytic activity of MamE and show that its behavior is consistent with the previously proposed checkpoint model for biomineralization. (Mus musculus) PubMed

 18490.

OsOTS1 is nuclear localized indicating a direct requirement of OsOTS1-dependent deSUMOylation activity in rice nuclei for salt tolerance.[OsOTS1] (Mus musculus) PubMed

 18491.

study found that the pic gene is associated with diarrhea and prolonged diarrhea in Peruvian children [pic] (Mus musculus) PubMed

 18492.

These findings demonstrate that the E3 ligase activity of mLANA contributes to gammaherpesvirus-driven germinal center B cell proliferation. (Mus musculus) PubMed

 18493.

We also identified a large extracellular protein, CmoA, which is conserved only in several Paenibacillus and related species. A cmoA mutant could neither form moving colonies nor move on hard agar media; however, motility was restored by exogenous CmoA. CmoA was located around cells and enveloped cell clusters. (Mus musculus) PubMed

 18494.

OsbZIP23 acts as a central regulator in ABA signaling and biosynthesis, and drought resistance in rice.[OsbZIP23] (Mus musculus) PubMed

 18495.

Third, Gata.a directs specific gene expression in the animal hemisphere domain, because beta-catenin/Tcf7 weakens the Gata.a-binding activity for target sites through a physical interaction in the vegetal cells. Thus, repressive regulation through protein-protein interactions among the maternal transcription factors is essential to establish the first distinct domains of gene expression in the chordate embryo. (Mus musculus) PubMed

 18496.

OsNAPL6 functions during stress response.[OsNAPL6] (Mus musculus) PubMed

 18497.

the expression of the gene, designated M truncatula Cystathionine-beta-Synthase-like1 (MtCBS1), using a promoter-beta-glucuronidase gene fusion revealed expression in infected root hair cells, developing nodules, and in the invasion zone of mature nodules.[MtCBS1] (Mus musculus) PubMed

 18498.

Mutant strains that have undergone specific genetic rearrangements allow us to propose that the distance between oriC and parS defines this "competence zone". Implications for the control of chromosome segregation in P. aeruginosa are discussed. (Mus musculus) PubMed

 18499.

Here we discover a novel protein, Tea, that is specifically enriched at telomeres to prevent telomere fusion. We also identify a complex consisting of Tea and two known capping proteins, Ver and Moi. The Moi-Tea-Ver (MTV) complex purified in vitro binds and protects ssDNA in a sequence-independent manner. (Mus musculus) PubMed

 18500.

Transcriptome analysis at early stage of bud development identified numerous genes that were up to 50-fold differentially expressed in wild-type/phyB-1 buds.[PhyB] (Mus musculus) PubMed

 18501.

Meningococcal factor H binding protein (FHbp) vaccine antigens with increased thermal stability and decreased binding of human factor H have been described. [FHbp] (Mus musculus) PubMed

 18502.

the VP30-NP interaction plays both essential and inhibitory roles in Ebola virus RNA synthesis. (Mus musculus) PubMed

 18503.

A rhodanese-like protein involved in thiouridine biosynthesis in Thermus thermophilus tRNA has been identified. [TtuD] (Mus musculus) PubMed

 18504.

Structural characterization of CYP260A1 from Sorangium cellulosum and its catalytic activity towards a mineralocorticoid has been reported. [CYP260A1] (Mus musculus) PubMed

 18505.

Data suggest that ChuY, an enzyme expressed downstream from chuW within the same heme utilization operon, is structurally similar to biliverdin reductase and forms a dimeric complex in solution that reduces anaerobilin to anaerorubin. [ChuY, anaerobilin reductase] (Mus musculus) PubMed

 18506.

The tick protein sialostatin L2 binds to annexin A2 and inhibits NLRC4-mediated inflammasome activation. [sialostatin L2] (Mus musculus) PubMed

 18507.

Protein conformation of a ligand-binding site on the Staphylococcus aureus DnaG primase C-terminal domain (Mus musculus) PubMed

 18508.

Functional and evolutionary characterization of a UDP-xylose synthase gene from the plant pathogen Xylella fastidiosa has been presented. [UDP-xylose synthase] (Mus musculus) PubMed

 18509.

The Crystal Structures of the N-terminal Photosensory Core Module of Agrobacterium Phytochrome Agp1 as Parallel and Anti-parallel Dimers (Mus musculus) PubMed

 18510.

The ClpX motor performs chemical transformations during the dwell and translocates the substrate in increments of 1-4 nm during the burst phase. This study characterized the complete mechanochemical cycle of ClpXP, showing that ADP release and ATP binding occur nonsequentially during the dwell, whereas ATP hydrolysis and phosphate release occur during the burst phase. [ClpX] (Mus musculus) PubMed

 18511.

RNA interference-mediated knockdown of KHARON mRNA results in failure of the calcium channel to enter the flagellar membrane, detachment of the flagellum from the cell body, and disruption of mitotic spindles. (Mus musculus) PubMed

 18512.

The authors also demonstrate that polynucleotide phosphorylase is required for full virulence in an in vivo model of Neisseria meningitidis infection.[polynucleotide phosphorylase] (Mus musculus) PubMed

 18513.

Finally, Fusobacterium nucleatum FAD-I activation of human BD-2 expression was mediated via both Toll-like receptor-1/2 (TLR-1/2) and TLR-2/6 heterodimerization.[FAD-I] (Mus musculus) PubMed

 18514.

These results indicate that EmpA and EmpB, but not EmpC, contribute to biofilm and adherence to ECM proteins; however, all the Emp pilins are important for Enterococcus faecium to cause infection in the urinary tract.[EmpA, EmpB, EmpC] (Mus musculus) PubMed

 18515.

Characterization of LuxI and LuxR protein homologs of N-acylhomoserine lactone-dependent quorum sensing system in Pseudoalteromonas sp. 520P1 has been reported. [LuxI], [LuxR] (Mus musculus) PubMed

 18516.

Data suggest that, in HepI, conformational rearrangements are important for catalysis; ODLA [O-deacylated E. coli Kdo(2)-lipid A] binding is accompanied by a significant stabilization of HepI; disruption of conformational dynamics of HepI may serve as a novel mechanism for inhibiting this and other glycosyltransferase enzymes. [hepI, heptosyltransferase I] (Mus musculus) PubMed

 18517.

Kinetics and structure of a cold-adapted hetero-octameric ATP phosphoribosyltransferase has been presented. [ATP phosphoribosyltransferase] (Mus musculus) PubMed

 18518.

Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris. (Mus musculus) PubMed

 18519.

BLIP-II binds PBP2a, although weakly compared to binding of beta-lactamases, and provides insights into the different binding strategies used for these targets [PBP2a] (Mus musculus) PubMed

 18520.

The Mycoplasma mobile ThrRS, the first example of a ThrRS naturally lacking the N1 domain, displays efficient post-transfer editing activity. In contrast, the Mycoplasma capricolum ThrRS, which harbors an N1 domain and a degenerate N2 domain, is editing-defective. (Mus musculus) PubMed

 18521.

The Mycoplasma mobile ThrRS, the first example of a ThrRS naturally lacking the N1 domain, displays efficient post-transfer editing activity. In contrast, the Mycoplasma capricolum ThrRS, which harbors an N1 domain and a degenerate N2 domain, is editing-defective. (Mus musculus) PubMed

 18522.

interaction of Samp1 and Ran in the inner nuclear membrane [Samp1] (Mus musculus) PubMed

 18523.

A Pdpcs1 overexpression was evidenced in date palm (Phoenix dactylifera L.) seedlings exposed to metals suggesting that 1-the Pdpcs1 gene is functional, 2-there is an implication of the enzyme in metal detoxification mechanisms. [PCS1] (Mus musculus) PubMed

 18524.

Helicobacter pylori minicatalase, a monomeric hemeprotein with catalase core homology, has been characterized. [minicatalase] (Mus musculus) PubMed

 18525.

Results show that Ni can act similarly to Cu in inducing petE and repressing petJ, thus leading to a partial switch between cytochrome c6 and plastocyanin and that their transcription is only altered by Ni in Cu-depleted medium. Also, plastocyanin seems to be essential for growth under conditions of excess Ni. [petE & petJ] (Mus musculus) PubMed

 18526.

Through the use of electronic structure methods, the nature of electronic excitations in pyruvate decarboxylase and its cofactor, thiamine diphosphate, has been presented. [Pyruvate decarboxylase] (Mus musculus) PubMed

 18527.

Ligand binding and conformational dynamics of NADH-dependent reduced ferredoxin: NADP+-oxidoreductase (NfnAB) has been reported. [NfnAB] (Mus musculus) PubMed

 18528.

The crystal structure of the C-terminal domain of arginine repressor (ArgR) from the pathogenic Corynebacterium pseudotuberculosis determined at 1.9 A resolution contains a tightly bound tyrosine at the arginine-binding site indicating hitherto unobserved promiscuity. [arginine repressor] (Mus musculus) PubMed

 18529.

results suggest that TaOEP16-2-5B plays an important role in heat and drought stress tolerance [TaOEP16-2-5B] (Mus musculus) PubMed

 18530.

mtHsp70 has the propensity to self-aggregate, and it depends on the action of the co-chaperone Hsp70-escort protein 1 (Hep1) to be produced functional [mtHsp70 and Hep1] (Mus musculus) PubMed

 18531.

RRM3 regulates epigenetic conversions in Saccharomyces cerevisiae in conjunction with Chromatin Assembly Factor I [Chromatin Assembly Factor I] (Mus musculus) PubMed

 18532.

DpaAB and SpoVAC, which control the synthesis and release of dipicolinic acid (DPA), respectively, from bacterial spores.[dpaB] (Mus musculus) PubMed

 18533.

Here is presented the crystal structure of a group II intron maturase from Eubacterium rectale, obtained at 2.1-A resolution, respectively. [group II intron maturase ] (Mus musculus) PubMed

 18534.

Here is presented the crystal structure of a group II intron maturase from Roseburia intestinalis, obtained at 1.2-A resolution, respectively. [group II intron maturase ] (Mus musculus) PubMed

 18535.

A comparative study between Rice telomere-binding protein and Nicotiana glutinosa telomere repeat binding factor through modeling of the complete proteins, physiochemical characterization, molecular docking simulation and DNA-protein docking.[RTBP1] (Mus musculus) PubMed

 18536.

The present study validates the importance of Lon and ClpP in intramacrophage growth and infection of the mammalian host by using unmarked deletion mutants of the Francisella tularensis live vaccine strain (LVS).[Lon, ClpP] (Mus musculus) PubMed

 18537.

Na(+)/Ca(2+) exchangers use the Na(+) electrochemical gradient across the plasma membrane to extrude intracellular Ca(2+). This study elucidates their mechanisms of extracellular ion recognition and exchange through a structural analysis of the exchanger from Methanococcus jannaschii (NCX_Mj) bound to Na(+), Ca(2+) or Sr(2+) in various occupancies and in an apo state. [sodium-calcium exchanger] (Mus musculus) PubMed

 18538.

The polar spine residue and water network of kinase Aurora A are essential for phosphorylation-driven activation, but an alternative form of the water network found in related kinases can support Tpx2-driven activation, suggesting that variations in the water-mediated hydrogen bond network mediate regulatory diversification in protein kinases. (aurora A kinase, human) (Mus musculus) PubMed

 18539.

Crystal structure of the Arterivirus nonstructural protein 11 (nsp11) that was shown to have endoribonuclease activity has been resolved. [nsp11] (Mus musculus) PubMed

 18540.

Crystal structure of the Porcine respiratory and reproductive syndrome virus nonstructural protein 11 (nsp11) that was shown to have endoribonuclease activity has been resolved. [nsp11] (Mus musculus) PubMed

 18541.

data show a synergistic effect of zwitterionic and negatively charged lipids on the activity of McjD; the zwitterionic lipids provide structural stability to McjD, whereas the negatively charged lipids are essential for its function. (Mus musculus) PubMed

 18542.

Processing of PatS, a morphogen precursor, in cell extracts of Anabaena sp. PCC 7120, has been reported. [PatS] (Mus musculus) PubMed

 18543.

The authors conclude that the binding activities of CFA/I pili for asialo-GM1, erythrocytes, and intestinal cells are inseparable, require the same amino acid residues in CfaE, and therefore depend on the same or very similar binding mechanisms.[CfaE] (Mus musculus) PubMed

 18544.

SUMOylation is an essential process and that adaptation to stress involves changes in global SUMOylation in C. glabrata Importantly, loss of the deSUMOylating enzyme CgUlp2 leads to highly reduced small ubiquitin-like modifier protein levels, and impaired growth, sensitivity to multiple stress conditions, reduced adherence to epithelial cells, and poor colonization of specific tissues in mice. (Mus musculus) PubMed

 18545.

The 1.8 A resolution structure of RIFMO complexed with RIF represents the precatalytic conformation that occurs before formation of the ternary E-RIF-NADPH complex. (Mus musculus) PubMed

 18546.

a HCMV-encoded miRNA, miR-UL148D, robustly accumulates during late stages of experimental latent HCMV infection in host cells and promotes HCMV latency[miR-UL148D] (Mus musculus) PubMed

 18547.

ToxR and VttRA act upstream of VttRB and that modifying the level of either vttRA or vttRB expression can strongly influence type 3 secretion systemgene expression.[VttRB, ToxR] (Mus musculus) PubMed

 18548.

These findings demonstrate the first example of host-parasite interactions via a parasite-derived ubiquitin-conjugating enzyme; an E2 that demonstrates a novel muscle protein stabilization function. (Mus musculus) PubMed

 18549.

Histone methyltransferase TXR1 is required for both H3 and H3.3 lysine 27 methylation [TRX1] (Mus musculus) PubMed

 18550.

These findings suggest that the novel nucleoside diphosphatase SA1684 links metabolic pathways and virulence gene expression and plays an important role in S. aureus virulence. (Mus musculus) PubMed

 18551.

we show that a novel transcriptional regulator XibR (named Xanthomonas iron binding regulator) of the NtrC family, is required for fine-tuning and co-coordinately regulating the expression of several iron regulated genes and virulence associated functions in phytopathogen Xanthomonas (Mus musculus) PubMed

 18552.

results indicate that altering cellular metabolism contributes to the ability of pathogens to resist manganese starvation and that ArlRS enables Staphylococcus aureus to overcome nutritional immunity by facilitating this adaptation[ArIRS] (Mus musculus) PubMed

 18553.

The molecular mechanisms of reduction of folate by DFHR from Thermotoga maritime has been described. [DHFR] (Mus musculus) PubMed

 18554.

A single glycoprotein expressed on the viral surface mediates entry into target cells. This glycoprotein, termed GPC, contains a membrane-associated signal peptide, a receptor-binding subunit termed GP1 and a fusion-mediating subunit termed GP2. here is presented the crystal structure of the fully glycosylated prefusion GP1-GP2 complex of the prototypic arenavirus LCMV at 3.5 A. [GPC] (Mus musculus) PubMed

 18555.

Knockout of PlasMei2 resulted in a complete block of Plasmodium yoelii transition from liver stage to blood stage infection in mice.[Mei2] (Mus musculus) PubMed

 18556.

In summary, the authors identified new amino acid residues critical for NleB1 activity and confirmed that these are required for the virulence function of NleB1.[NleB1] (Mus musculus) PubMed

 18557.

Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but only myoB is required for conidial viability.[myoB, myoE] (Mus musculus) PubMed

 18558.

We engineered a library of infectious HCV with all codons represented at most positions in the ectodomain of the E2 gene. Nine variants showed reduced dependence on scavenger receptor class B type I (SR-BI) for infection. (E2 gene) (Mus musculus) PubMed

 18559.

Aggregatibacter actinomycetemcomitans Omp29 induces TGF-beta-regulated apoptosis signal in human gingival epithelial cells via fibronectin/integrin beta1/FAK cascade. [Omp29] (Mus musculus) PubMed

 18560.

our findings reveal the core calcineurin-Crz1 stress response cascade is maintained from ascomycetes to a pathogenic basidiomycete fungus, but its output in C. neoformans appears to be adapted to promote fungal virulence. (Mus musculus) PubMed

 18561.

Two protein-lysine methyltransferases (PKMTs) that catalyze methylation of recombinant OmpB at multiple sites with varying sequences have been identified and overexpressed. PKMT1 catalyzes predominantly monomethylation, whereas PKMT2 catalyzes mainly trimethylation. Rickettsial PKMT1 and PKMT2 are unusual in that their primary substrate appears to be limited to OmpB (Mus musculus) PubMed

 18562.

Two protein-lysine methyltransferases (PKMTs) that catalyze methylation of recombinant OmpB at multiple sites with varying sequences have been identified and overexpressed. PKMT1 catalyzes predominantly monomethylation, whereas PKMT2 catalyzes mainly trimethylation. Rickettsial PKMT1 and PKMT2 are unusual in that their primary substrate appears to be limited to OmpB (Mus musculus) PubMed

 18563.

Report shows the crystal structure of the N-terminal dimerization/oligomerization domain of TurB, an MvaT homologue in Pseudomonas putida KT2440. Data identify two dimerization sites; the structure of the central dimerization site is almost the same as the corresponding region of H-NS, whereas the terminal dimerization sites are different. [TurB] (Mus musculus) PubMed

 18564.

Thus, ovine Herpesvirus 2 glycoproteins B-, H- and L are sufficient to induce membrane fusion, while glycoprotein Ov8 plays an enhancing role by an unknown mechanism.[B, H, L] (Mus musculus) PubMed

 18565.

ORP1L-VAP complexes also support transport of LDL-derived cholesterol from endosomes to the endoplasmic reticulum when ORP1L was bound to human adenovirus RIDalpha. RIDalpha-induced lipid trafficking also attenuated proinflammatory signaling by Toll-like receptor 4, which has a central role in adenovirus pathogenesis and is known to be tightly regulated by cholesterol-rich "lipid rafts."[RIDalpha] (Mus musculus) PubMed

 18566.

The studies demonstrate that hyaluronic acid is a relevant component of the S. aureus biofilm matrix, and HysA is important for dissemination from a biofilm infection. [HysA] (Mus musculus) PubMed

 18567.

A novel Aspergillus fumigatus rhomboid family putative protease, RbdA, involved in hypoxia sensing and virulence, has been identified. [RbdA] (Mus musculus) PubMed

 18568.

Data suggest that subunits nrdA2 and nrdB2 form active alpha2/beta2 complex in which a glutamate in position 350 in nrdB2 is a key player in communication between the two subunits and in initiation of radical transport via conformational gating. [nrdA2, ribonucleoside diphosphate reductase A2 subunit; nrdB2, ribonucleoside diphosphate reductase B2 subunit] (Mus musculus) PubMed

 18569.

Ligand-bound Structures and Site-directed Mutagenesis Identify the Acceptor and Secondary Binding Sites of Streptomyces coelicolor Maltosyltransferase GlgE. (Mus musculus) PubMed

 18570.

Kinase activation in vivo could result from direct interaction between Stt7 and the b6f complex or long-range reduction of Stt7 by superoxide, known to be generated in the b6f complex by quinol oxidation. (Mus musculus) PubMed

 18571.

The Borrelia burgdorferi CheY3 response regulator is essential for chemotaxis and completion of its natural infection cycle.[CheY] (Mus musculus) PubMed

 18572.

The Bt9 bunt resistance locus was mapped and shown to be distinct from the Bt10 locus. (Mus musculus) PubMed

 18573.

Biosynthesis of the metalloclusters of nitrogenase, NifDK, has been described. [NifDK] (Mus musculus) PubMed

 18574.

Dynamic light-scattering experiments are consistent with the structural observations and indicate that FepB forms a trimer in a iron-Enterobactin-dependent manner.[FepB] (Mus musculus) PubMed

 18575.

Our data suggest that EIPR-1 is a new interactor of the EARP complex and that dense-core vesicle cargo sorting depends on the EARP-dependent trafficking of cargo through an endosomal sorting compartment (Mus musculus) PubMed

 18576.

The impact of the RNA chaperone Hfq upon the steady state levels of 280 sRNA transcripts is described, and we found 13 sRNAs that are co-regulated with SPI1 and SPI2 virulence genes. We report the first example of an sRNA, STnc1480, that is subject to silencing by H-NS and subsequent counter-silencing by PhoP and SlyA. (Mus musculus) PubMed

 18577.

This study expands the knowledge on the role of DgcZ in regulation of surface attachment and suggests that it interconnects surface sensing and adhesion via multiple routes. [DgcZ] (Mus musculus) PubMed

 18578.

The ACR-incorporated LUVs provide a purified defined system amenable to EPR, optical and vibrational spectroscopy, and fluorescence resonance energy transfer measurements of structural changes of ACRs with the molecules in a demonstrably functional state. (Mus musculus) PubMed

 18579.

One of the Masc-R strains weakly expressed Masc-R in various tissues. Females heterozygous for the transgene expressed male-specific isoform of the Bombyx homolog of insulin-like growth factor II mRNA-binding protein (ImpM) and Bmdsx (Mus musculus) PubMed

 18580.

We also show that this intestine-to-neuron feeding-state regulation of srh-234 involves a subset of insulin-like peptides. These results combined suggest that chemoreceptor gene expression is regulated by both cell-autonomous and non-cell-autonomous transcriptional mechanisms mediated by MEF2 and bHLH factors, which may allow animals to fine-tune their chemosensory responses in response to changes in their feeding state. (Mus musculus) PubMed

 18581.

our work shows that the functionally redundant DARS1 and DARS2 regions play different roles in replication control. DARS1 is mainly involved in maintaining the origin concentration, whether DARS2 is also involved in maintaining single cell synchrony. (Mus musculus) PubMed

 18582.

SltF functions as a newly identified class of lytic transglycosylases and that its autolytic activity is uniquely modulated by two rod proteins, FlgB and FlgF. [SltF, flgB, FlgF] (Mus musculus) PubMed

 18583.

our study shows that the AAA ATPase LRD6-6 inhibits plant immunity and cell death most likely through modulating MVBs-mediated vesicular trafficking in rice (Mus musculus) PubMed

 18584.

FlgZ impacts swarming motility via its interactions with flagellar stator protein MotC. [FlgZ] (Mus musculus) PubMed

 18585.

The authors show that populations that shift ModA2 expression from OFF to ON within the middle ear induce significantly greater disease severity than populations that are unable to shift.[ModA2] (Mus musculus) PubMed

 18586.

An endoglucanase isolated from Aspergillus aculeatus F-50 (FI-CMCase), which is classified into the glycoside hydrolase (GH) family 12, was demonstrated to be effectively expressed in the industrial strain Pichia pastoris. Here, the crystal structure and complex structures of P. pastoris-expressed FI-CMCase were solved to high resolution. [FI-CMCase] (Mus musculus) PubMed

 18587.

The characteristic conformations of l-Asp and d-Asp in the active site provide a straight structural evidence for the racemization mechanism of EcL-DER.[Ecl-DER] (Mus musculus) PubMed

 18588.

Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation.( (Mus musculus) PubMed

 18589.

PvdN turned out to be required for a specific modification of pyoverdine, whereas the overall amount of fluorescent pyoverdines was not altered by the mutation. The mutant strain grew normally under iron-limiting conditions. (Mus musculus) PubMed

 18590.

FliS unfolds in a noncooperative way and its native state shows features reminiscent of the molten globule state of proteins possessing substantial structural plasticity.[FliS] (Mus musculus) PubMed

 18591.

Survival motor neuron 1, and survival motor neuron 2, depletion results in increased alternative splicing events. [survival motor neuron 2] (Mus musculus) PubMed

 18592.

This study evaluated the conformation attributes of PapD and FimC and their role in pilus formation.[PapD; FimC] (Mus musculus) PubMed

 18593.

Francisella novicida (F. novicida) lpxA functionally complements an E. coli lpxA knockout mutant and efficiently transfers 3-OH-C14 as well as R-3-hydroxymyristoyl-acyl carrier protein in E. coli.[LpxA] (Mus musculus) PubMed

 18594.

Under aerobic conditions, the ferrous coproheme-decarboxylase (HemQ) complex is rapidly and selectively oxidized by O2 to the ferric state: [HemQ] (Mus musculus) PubMed

 18595.

structural and biochemical analyses verified SP-PTP as a canonical tyrosine-specific low molecular weight protein tyrosine phosphatases.[SP-PTP] (Mus musculus) PubMed

 18596.

YlaJ and YhcN have a role in spore germination that is not yet well defined, but these proteins are likely to contribute, directly or indirectly, to early events in germination, including effective SleB function [YlaJ, YhcN] (Mus musculus) PubMed

 18597.

three merozoite proteins (PvTRAg36, PvATRAg74, and PvTRAg38) of this family interact with Band 3 on human erythrocytes through its three exofacial loops.[ (PvTRAg36, PvATRAg74, and PvTRAg38)] (Mus musculus) PubMed

 18598.

the crystal structure of Est24, an octameric carbohydrate acetylesterase from Sinorhizobium meliloti, at 1.45 A resolution was determined and its biochemical properties was investigated.[Est24] (Mus musculus) PubMed

 18599.

Phenotype studies revealed that the double deletion yju3Deltamgl2Delta displayed a growth defect that was partially restored by MGL2 overexpression.[MGL2] (Mus musculus) PubMed

 18600.

The Ribosome Restrains Molten Globule Formation in Stalled Nascent Flavodoxin (Mus musculus) PubMed

 18601.

Fhf2a is represented by three transcripts, one of which is expressed in the developing heart. These transgenics are useful tools for studies of development of the CCS and cardiac disease. (Mus musculus) PubMed

 18602.

analysis of how cryptic RNase H fold exonuclease PF2046 processes A form ss DNA [RNase H] (Mus musculus) PubMed

 18603.

CagU is a bacterial inner membrane-associated protein, partially processed at the C terminus, and that it interacts with the VirB6 and VirB8 homologs CagW and CagV, respectively.[Cagu] (Mus musculus) PubMed

 18604.

The pattern of disease risk across PAN2 and MAP3K7CL genotypes provided clear evidence for a significant epistatic foundation for this disease, a risk further impacted by MHC haplotypes. We also observed a genotype-phenotype correlation wherein an earlier age of onset is correlated with an increased number of risk alleles at PAN2 and MAP3K7CL. (Mus musculus) PubMed

 18605.

These findings suggest that ubiquitously conserved essential GTPase Der is involved in 50S ribosomal subunit biosynthesis in various bacteria and that the linker and C-terminal regions may participate in species-specific recognition or interaction with the 50S ribosomal subunit.[Der] (Mus musculus) PubMed

 18606.

Protective efficacy is induced in mice by genetically attenuated mid-to-late liver-stage arresting Plasmodium berghei mrp2-lacking parasites. [mrp2] (Mus musculus) PubMed

 18607.

Results indicate that S. mutans phosphate-binding-protein (PstS) is a potential target antigen capable of inducing specific and protective antibody responses after sublingual administration [phosphate-binding-protein (PstS)]. (Mus musculus) PubMed

 18608.

Characterization of a Salmonella sugar kinase (FraD) essential for the utilization of fructose-asparagine has been reported. [FraD] (Mus musculus) PubMed

 18609.

Oxidative stress activates the homeostatic response to stress characterized by the phosphorylation eIF2a, the attenuation of protein synthesis, and the transcription of genes participating in the unfolded protein response and antioxidant processes, forming a part of an integrated stress response. [eiF2a] (Mus musculus) PubMed

 18610.

this study detected the expression pattern of HSFY in the testes and epididymis and demonstrated that its expression was not regulated by transient elevated temperature.[HSFY] (Mus musculus) PubMed

 18611.

RelLS20 constitutes the prototype of a new family of relaxases. The identification of this novel relaxase family will have an important impact in different aspects of future research in the field of HGT in Gram-positive bacteria in general, and specifically in the phylum of Firmicutes, and in gut microbiome research. (Mus musculus) PubMed

 18612.

we show that both IFT43 and IFT140 are involved in mobilizing ciliary precursors from the cytoplasmic pool during flagellar regeneration, suggesting a novel role of IFT-A in transporting ciliary components in the cytoplasm to the peri-basal body region. (Mus musculus) PubMed

 18613.

In yeast two-hybrid assays, wild-type and putative constitutively active EXC-1 binds to the LIM-domain protein EXC-9, whose homolog, cysteine-rich intestinal protein, is enriched in mammalian intestine. (Mus musculus) PubMed

 18614.

We propose that SufT, and by extension the DUF59 domain, is an accessory factor that functions in the maturation of FeS proteins.In S. aureus, the involvement of SufT is maximal during conditions of high demand for FeS proteins (Mus musculus) PubMed

 18615.

Here we describe the mRNA expression pattern of PHDs in chick embryos. Up to embryonic day 2, PHDs are weak without specific localisation, whereas from day 3 localised expression was observed in the eye, branchial arches and dermomyotome. (Mus musculus) PubMed

 18616.

he loss of O10 function disrupts this ring-shaped distribution of 22-kD and 16-kD zeins, resulting in misshapen PBs. These results showed that O10, as a newly evolved PB protein, is essential for the ring-shaped distribution of 22-kD and 16-kD zeins and controls PB morphology in maize endosperm. (Mus musculus) PubMed

 18617.

Because DmxB can be-at least partially-functionally replaced by a heterologous diguanylate cyclase, these results altogether suggest a model in which a minimum threshold level of c-di-GMP is essential for the successful completion of multicellular development in M. xanthus (Mus musculus) PubMed

 18618.

Transformation in strains producing only the PilE (pilin) Ntd has the same genetic determinants as wild-type transformation. The Ntd corresponds to the alternative product of S-pilin cleavage, a specific proteolysis unique to pathogenic Neisseria (Mus musculus) PubMed

 18619.

This study provides genomic insights into the two interspecific hybridization events: one produced the present broad leaf and another formed okra leaf phenotype with complete OKRA, that occurred during allotetraploid cotton formation (Mus musculus) PubMed

 18620.

Findings indicate that Sac7d is able to largely coat duplex DNA by binding in alternating head-to-head and tail-to-tail orientations: [Sac7d] (Mus musculus) PubMed

 18621.

Eliminating HPFSa drastically increased ribosome occupancy at the 5' end of specific mRNAs under nutrient-limited conditions, suggesting that HPFSa may suppress translation initiation (HPFSa). (Mus musculus) PubMed

 18622.

The utility of the method was established by tagging genes encoding proteins of known localization such as TcFCaBP (flagellar calcium binding protein) and TcVP1 (vacuolar proton pyrophosphatase), and two proteins of undefined or disputed localization, the TcMCU (mitochondrial calcium uniporter) and TcIP3R (inositol 1,4,5-trisphosphate receptor). (Mus musculus) PubMed

 18623.

data suggest that PG0162 is a sigma factor that may play an important role in the virulence regulatory network in P. gingivalis [PG0162]. (Mus musculus) PubMed

 18624.

function of IsdH may have an overall stimulatory effect on S. aureus heme acquisition and growth. (Mus musculus) PubMed

 18625.

Further analysis, including proteomics and stimulation analyses, identified phosphoglycerate kinase as a stimulatory factor for neutrophils.[phosphoglycerate kinase] (Mus musculus) PubMed

 18626.

TbFT1-3 mediates the uptake of folate and classical antifolates in trypanosomes, and TbFT1-3 loss-of-function is a mechanism of antifolate drug resistance. (Mus musculus) PubMed

 18627.

It was concluded that pncA mutation typing, with resistance testing and spoligotyping, was useful in identifying a nosocomial TB outbreak and demonstrating its resolution after implementation of infection control measures. [pncA] (Mus musculus) PubMed

 18628.

the use of a phenylselenyl-modified thymidine incorporated into a specific position of a partially unwound DNA substrate in crosslinking studies of Escherichia coli topoisomerase I to gain new insights into its catalytic mechanism, is reported.[Top I] (Mus musculus) PubMed

 18629.

macrophage-internalized C. glabrata cells express CgFtr1 on the cell membrane indicative of an iron-restricted macrophage internal milieu, and Cgvps34Delta cells display better survival in iron-enriched medium-cultured macrophages. Overall, our data reveal the centrality of PI3K signaling in iron metabolism and host colonization. (Mus musculus) PubMed

 18630.

the X-ray structure of the Acp catalytic domain (AcpCD) at 1.76 A resolution, is reported. AcpCD has a unique crescent-shaped structure, forming a deep groove for substrate-binding at the center of the protein.[Acp] (Mus musculus) PubMed

 18631.

the first structure of the catalytic domain (residues 201-589) of the class I PhaC from Cupriavidus necator (formerly Ralstonia eutropha) to 1.80 A resolution. (Mus musculus) PubMed

 18632.

CtXyl5A is capable of hydrolyzing xylans that are extensively decorated and that are recalcitrant to classic endo-xylanase attack. (Mus musculus) PubMed

 18633.

The Type B Flagellin of Hypervirulent Clostridium difficile Is Modified with Novel Sulfonated Peptidylamido-glycans.( (Mus musculus) PubMed

 18634.

The crystal structure of the recombinant PLL.l-fucose complex confirmed that at least three sites were fucose-binding. Moreover, the crystal structures indicated that some of the other sites are masked either by the tetrameric nature of the lectin or by incorporation of the C terminus of the lectin into one of these sites. (Mus musculus) PubMed

 18635.

The Chlamydia pneumoniae Adhesin Pmp21 Forms Oligomers with Adhesive Properties. (Mus musculus) PubMed

 18636.

this study extends our general knowledge about multi-domain KDM5 histone demethylases and provides new details on the chromatin-level regulation of fungal secondary metabolite production. (Mus musculus) PubMed

 18637.

results reveal the role of each domain in the elementary steps of the reaction cycle and provide the first direct evidence of the processive movement of TrCel6A on crystalline cellulose. (Mus musculus) PubMed

 18638.

Our results demonstrated that HCV p7 has dual roles as a viroporin and as a lipid raft adhesion factor. This ion channel-independent function of p7 might be an attractive target for development of anti-HCV compounds. (Mus musculus) PubMed

 18639.

The enzyme exhibits a strong substrate preference toward xylooligosaccharides; hence it is named xylooligosaccharide oxidase (XylO). Chemical analyses of the product formed upon oxidation of xylobiose revealed that the oxidation occurs at C1, yielding xylobionate as product. [xylooligosaccharide oxidase] (Mus musculus) PubMed

 18640.

the ESCRT regulator Did2 coordinates precise maturation of endosomes and thus provides the correct membrane identity for efficient endosomal long-distance transport. (Mus musculus) PubMed

 18641.

These results indicate that Ros1 is a master regulator of late development in U. maydis (Mus musculus) PubMed

 18642.

immunological features and inhibitory functions against target serine proteases (serpin isoform 3 (SmSPI)) (Mus musculus) PubMed

 18643.

Cyc17 is involved in regulating spindle pole attachment, and is thus essential for chromosome segregation at meiosis.[Cyc17] (Mus musculus) PubMed

 18644.

Competitive inhibition experiments with other pneumococcal hTSP-1 adhesins demonstrated that PspC and PspC-like Hic recognize similar domains, whereas PavB and Hic can bind simultaneously to hTSP-1. (Mus musculus) PubMed

 18645.

The activity of the Escherichia coli O-antigen polymerase (Wzy) is dependent on the first sugar of the O-antigen repeat unit to produce the O-antigen polymerization and therefore, there is a need for a concerted action with the enzyme transferring the initial HexNAc to undecaprenyl phosphate (UDP-HexNAc: polyprenol-P HexNAc-1-P transferase) [ O-antigen polymerase (Wzy)]. (Mus musculus) PubMed

 18646.

ChuY acts as a reductase in heme homeostasis to maintain the virulence potential of E. coli CFT073 [chuY] (Mus musculus) PubMed

 18647.

LipW contains a deep, expansive substrate-binding pocket with only a narrow, restrictive active site, suggesting tight substrate selectivity for short, unbranched esters: [LipW] (Mus musculus) PubMed

 18648.

This study showed that succinate (SDH) activity in the liver and heart, cytochrome c oxidase (COX) and catalase activity in the liver, Sdh mRNA levels in the liver, and Cox mRNA levels in the liver and heart are sensitive criteria to evaluate the dietary iron requirements of broilers.[SDH; COX] (Mus musculus) PubMed

 18649.

we show that TcpB, like its homolog CofB, initiates pilus assembly. (Mus musculus) PubMed

 18650.

conserved functions of MOZART1/Mzt1 through interactions with gamma-tubulin complex subunits and gamma-tubulin complex receptors, are reported.[Mozart1] (Mus musculus) PubMed

 18651.

crystallized and solved the structure of 54-kDa RagB, which revealed a single domain centered on a curved helical scaffold; it consists of 4 tetratrico peptide repeats (TPR1-4), each arranged as 2 helices connected by a linker, plus two extra downstream capping helices; the concave surface bears 4 large intertwined irregular inserts (A-D), which contribute to an overall compact moiety [RagB] (Mus musculus) PubMed

 18652.

The structure establishes nicotine oxidoreductase (NicA2) as a member of the monoamine oxidase family: [NicA2] (Mus musculus) PubMed

 18653.

Golgi SNARE 12 (designated as GOS12) protein of soybean interacts with soybean mosaic virus P3N-PIPO via a two-hybrid yeast system.[P3N-PIPO] (Mus musculus) PubMed

 18654.

Data show that the structure of pimeloyl-acyl carrier protein methyl esterase BioG is composed of an alpha-helical lid domain and a core domain that contains a central seven-stranded beta-pleated sheet: [BioG] (Mus musculus) PubMed

 18655.

Data suggest that the function of copper chaperone (copZ) on biofilm and competitiveness is independent of copper resistance and CopZ is a global regulator for biofilm and other virulence factors [copper chaperone (copZ)]. (Mus musculus) PubMed

 18656.

We selected a previously uncharacterized peptidase, which we term Major aspartyl peptidase 1 (May1), for detailed study due to its substantial contribution to extracellular proteolytic activity[May1] (Mus musculus) PubMed

 18657.

goat BSP proteins have an affinity for caseins and whey proteins.[BSP] (Mus musculus) PubMed

 18658.

Two-hybrid assays confirm an intracellular interaction between the Escherichia coli enzymes EntA and EntB. Experimental evidence supports a computational prediction of a ternary EntA-EntB-EntE complex. [EntA, EntB, EntE] (Mus musculus) PubMed

 18659.

The role of ubiI protein in the biofilm formation and pathogenicity of uropathogenic E. coli was studied.[ubiI] (Mus musculus) PubMed

 18660.

The crystal structure of the HigBA complex displays a hetero-tetramer (HigBA)2 form comprised by two HigB and two HigA subunits.[HigA, HigB] (Mus musculus) PubMed

 18661.

The large multisubunit transport protein particle (TRAPP) II complex is a bona fide guanine nucleotide exchange factor for the yeast Rab11 homologues Ypt31/32.[Ypt31, Ypt32] (Mus musculus) PubMed

 18662.

Mutation frozen was localized to the previously unannotated zebrafish myo18b gene. Myo18b mutant embryos display disrupted sarcomeric organization. (Mus musculus) PubMed

 18663.

This study combined a variety of microbiological, genetic, biochemical, and biophysical approaches to investigate the activation of the alginate biosynthesis operon promoter by a key transcription factor named AmrZ.[AmrZ] (Mus musculus) PubMed

 18664.

disulfide bond is critical for efficient protein translocation through the TIM23 complex and for dynamic gating of its preprotein-conducting channel.[TIM23] (Mus musculus) PubMed

 18665.

PvTRAg38 binds to two erythrocyte receptors basigin and band 3 through P2 and P4 regions, respectively, to facilitate parasite growth. (Mus musculus) PubMed

 18666.

activation of calcineurin requires Mid1, an endoplasmic reticulum-localized calcium channel regulatory protein implicated in the oxidative stress response.[Mid1] (Mus musculus) PubMed

 18667.

we identified an ABC transporter, that we designated NiuBDE, as a novel H. pylori nickel transport system (Mus musculus) PubMed

 18668.

We show that the S. aureus-secreted protein staphylococcal protein A (SpA), which is well-known for interacting with host targets, also binds to specific P. aeruginosa cell surface molecules and alters two persistence-associated P. aeruginosa behaviors: biofilm formation and uptake by host immune cells [protein A]. (Mus musculus) PubMed

 18669.

These data indicate that RBF1 is a virulence gene essential for the focal biotrophic interfacial complex formation, which is critical for the rice blast fungus to suppress host immune responses. (Mus musculus) PubMed

 18670.

results define a specialized organization of the TAF12 variants and non-redundant roles for the two TAF12 variants in the unicellular C. albicans genome (CaTAF12L and CaTAF12). (Mus musculus) PubMed

 18671.

we present the first structure of S. aureus TarS, the enzyme responsible for polyribitol phosphate beta-O-GlcNAcylation (Mus musculus) PubMed

 18672.

Sac6 was involved in regulation of secretion of lytic enzymes and virulence of C. albicans.[Sac6] (Mus musculus) PubMed

 18673.

FAP174 binds AKAP240 previously identified in the C2 portion of the central pair apparatus.[FAP174, AKAP240] (Mus musculus) PubMed

 18674.

Our results illustrated that, by inhibiting SH3BGR, miR-K6-3p enhances cell migration and angiogenesis by activating the STAT3 pathway, and thus contributes to the dissemination and angiogenesis of KSHV-induced malignancies (Mus musculus) PubMed

 18675.

Rng8 and Rng9 accumulate on the fusion focus, dependent on Myo51 and tropomyosin Cdc8. A tropomyosin mutant allele, which compromises Rng8/9 localization but not actin binding, similarly leads to multiple stable dots instead of a single focus. By contrast, myo51 deletion does not strongly affect fusion focus coalescence (Mus musculus) PubMed

 18676.

Meta-analysis showed that in Asia 1 EPIYA-D motif was significantly associated with increased gastric cancer (GC) risk. Multiple EPIYA-C motifs were associated with increased peptic ulcer disease and duodenal ulcer risk, particularly in Asia. In the United States and Europe, multiple EPIYA-C motifs were associated with increased GC risk. [CagA] (Mus musculus) PubMed

 18677.

Ptb catalysis involved ternary complex formation. Additionally, Ptb could utilize unnatural branched-chain substrates such as 2-ethylbutyryl CoA, albeit with lower efficiency, consistent with a potential involvement of this enzyme in the conversion of the carboxylic acid additives into CoA primers for BCFA biosynthesis. (Mus musculus) PubMed

 18678.

Immunofluorescence assay of transgenic P. knowlesi parasites expressing epitope-tagged recombinant Skeleton-Binding Protein 1 revealed a punctate staining pattern reminiscent of Maurer's clefts, following infection of either monkey or human erythrocytes. [Skeleton-Binding Protein 1] (Mus musculus) PubMed

 18679.

SCAV-3 is essential for preserving lysosomal membrane stability and that modulation of lysosome integrity by the insulin/IGF-1 signaling pathway affects longevity.[SCAV-3] (Mus musculus) PubMed

 18680.

Ups2-Mdm35 functions as a phosphatidyl serine transfer protein and enhances mitochondrial phosphatidylethanolamine synthesis in response to the cellular metabolic state.[Pps2, Mdm35] (Mus musculus) PubMed

 18681.

-ray crystal structures of the ligand-free CYP107L2 and its complex with lauric acid were determined at the resolution of 2.6 and 2.5 A, respectively. [CYP107L2] (Mus musculus) PubMed

 18682.

AMSDH surprisingly includes an isomerization process within its known catalytic mechanism. These data establish a hidden intrinsic isomerization activity of the dehydrogenase and allow us to propose a pitcher-catcher type of catalytic mechanism for the isomerization. (Mus musculus) PubMed

 18683.

study identified ATG8 in Plasmodium liver forms as an important effector that controls the development and fate of organelles, e.g., the clearance of micronemes that are required for hepatocyte invasion and the expansion of the apicoplast that produces many metabolites indispensable for parasite replication [ATG8]. (Mus musculus) PubMed

 18684.

Here, we elucidate the structure-function relationship of the transcription factor ComR, a new member of the RNPP family, which positively controls competence for natural DNA transformation in streptococci (Mus musculus) PubMed

 18685.

results show that, unlike the majority of viral inhibitors of interferon signalling, C6 inhibits the signalling pathway at a late stage once the proteins required [c6] (Mus musculus) PubMed

 18686.

GhSARP1 might negatively regulate the response to salt stress mediated by the ubiquitination in cotton.[GhSARP1] (Mus musculus) PubMed

 18687.

NAMPT inhibited endothelial progenitor cell senescence through an SIRT1 AS lncRNA/miR-22/SIRT1 pathway.[SIRT1 AS lncRNA] (Mus musculus) PubMed

 18688.

Num1 adopts an extended, polarized conformation. Its N-terminal coiled-coil domain (Num1CC) is proximal to mitochondria, and the C-terminal pleckstrin homology domain is associated with the plasma membrane.[Num1] (Mus musculus) PubMed

 18689.

Ups2-Mdm35 complexes (SLMO2-TRIAP1 in humans) serve as phosphatidylserine (PS)-specific lipid transfer proteins in the mitochondrial intermembrane space, allowing formation of Phosphatidylethanolamine by Psd1 in the inner membrane.[Ups2, Mdm35] (Mus musculus) PubMed

 18690.

The identification of this pore binding site sheds light on the mechanism of barbiturate inhibition of cationic pLGICs and allows the rationalization of several structural and functional features previously observed for barbiturates. (Mus musculus) PubMed

 18691.

TcNRBD1 is associated with different parts of the translation process [NRBD1] (Mus musculus) PubMed

 18692.

OsLBD37 and OsLBD38, two class II type LBD proteins, are involved in the regulation of heading date by controlling the expression of Ehd1 in rice. [OsLBD37], [OsLBD38] (Mus musculus) PubMed

 18693.

Data show that overexpression of microRNA miR-17-92 in differentiated C2C12 myoblast cells dramatically reduced the expression of E2F3b protein: [miR-17-92] (Mus musculus) PubMed

 18694.

Domain architecture of MRG701 in rice has been reported. [MRG701] (Mus musculus) PubMed

 18695.

Study describes the equilibrium ensemble of structures of Slo2.2, a neuronal Na(+)-activated K(+) channel, as a function of the Na(+) concentration; find that Slo2.2 exists in multiple closed conformations whose relative occupancies are independent of Na(+) concentration. [Slo2.2] (Mus musculus) PubMed

 18696.

Structural insights unravel the zymogenic mechanism of the virulence factor gingipain K from Porphyromonas gingivalis, a causative agent of gum disease from the human oral microbiome (Mus musculus) PubMed

 18697.

propose ICP0 promotes transcription of latency-associated transcripts during establishment or maintenance of latent infection, much as it promotes lytic gene transcription; report introduces concept that a lytic viral protein can be expressed during latent infection and can serve dual roles to regulate viral chromatin to optimize latent infection in addition to role in epigenetic regulation during lytic infection [ICP0] (Mus musculus) PubMed

 18698.

These results strongly suggest that the difference of toxicity between Cry1Aa and Cry1Ac to E. kuehniella is due to a deficient oligomerisation of Cry1Aa. Ephestia kuehniella tolerance to Bacillus thuringiensis Cry1Aa is associated with reduced oligomer formation. [Cry1Aa] (Mus musculus) PubMed

 18699.

the mitochondrial division factor Dnm1 in yeast or Drp1 in mammalian cells is dispensable for mitophagy.[Dnm1] (Mus musculus) PubMed

 18700.

these results reveal Cig57 to be a significant virulence factor that co-opts clathrin-mediated trafficking, via interaction with FCHO2, to facilitate the biogenesis of the fusogenic Coxiella replicative vacuole and enable intracellular success of this human pathogen (Mus musculus) PubMed

 18701.

Conformational changes in the glycoprotein B fusion domain are important for activation of membrane fusion during viral entry and that in the absence of a host target membrane, this change results in irreversible inactivation of virions. [glycoprotein B] (Mus musculus) PubMed

 18702.

map-based cloning and breeding application [twin-grain1 (tg1)] (Mus musculus) PubMed

 18703.

immunofluorescence microscopy localized TbRFT1 to both the endoplasmic reticulum and the Golgi, consistent with the proposal that TbRFT1 plays a direct or indirect role in GPI anchor glycosylation in the Golgi apparatus. (Mus musculus) PubMed

 18704.

Carbon-sulfur lyase (C-S lyase) has a broad substrate specificity toward sulphur-containing amino acids with aminoethyl-L-cysteine and L-cystine being the most effective substrates over L-cysteine and L-cystathionine: [C-S lyase ] (Mus musculus) PubMed

 18705.

AmEgr, a honeybee homolog of Egr-1, was transiently upregulated in the developing brain during the early to mid pupal stages.[AmEgr] (Mus musculus) PubMed

 18706.

Sun4p and Dse2p, co-localize to the yeast birth scar.[Sun4p] (Mus musculus) PubMed

 18707.

Bch1 and Cfr1 proteins constitute the simplest form of an exomer. (Mus musculus) PubMed

 18708.

This study showed that increased expression of the membrane-associated ABC protein LptB can suppress defects of LptC, which participates in the formation of the periplasmic bridg; this reveals functional interactions between these two components and supports a role of LptB in the assembly of the Lpt machine.[LptB; LptC] (Mus musculus) PubMed

 18709.

The ternary complex structure of d-mandelate dehydrogenase (d-ManDH) with NADH and anilino(oxo)acetate has been reported. [d-ManDH] (Mus musculus) PubMed

 18710.

1. Bip/Grp78: The level of BiP/GRP78 was significantly higher in guinea pigs with noise induced hearing loss. 2. CHOP/Gadd153: The level of CHOP/Gadd153 was increased at 1 d post noise exposure, achieving a peak that was maintained until 4 d, after which it returned to baseline levels by 14 d post noise exposure. (Mus musculus) PubMed

 18711.

a new angle to cognize the relationship between membrane binding and entrance of the methyl donor of UbiG, which is of benefit for better understanding the O-methyl transfer process for ubiquinone biosynthesis. [UbiG] (Mus musculus) PubMed

 18712.

increased spatial separation of the 2 arrested forks encountering an extended Tus/Ter barrier impairs the coordination of DNA ends generated by the processing of the stalled forks.[Tus] (Mus musculus) PubMed

 18713.

YmdB plays a central role in biofilm formation and antibiotic susceptibility, YmdB regulates sucA expression. [sucA] [YmdB] (Mus musculus) PubMed

 18714.

These studies demonstrate that the Sae two-component regulatory system is a positive transcriptional regulator that binds directly to the TSST-1 promoter, and the data suggest that Sae is required for expression of TSST-1.[Saes; TSST-1] (Mus musculus) PubMed

 18715.

both SPN and SLO contribute significantly to S. pyogenes pathogenesis in these virulence assays.[NADase, Streptolysin O] (Mus musculus) PubMed

 18716.

These findings indicated that Cx43/miR-206 is involved in the pathogenesis of early stage steroid-induced avascular necrosis of the femoral head. (Mus musculus) PubMed

 18717.

These data establish human adenovirus E1A as the first known viral A-kinase anchoring protein (Mus musculus) PubMed

 18718.

Data show that sulfide:quinone qxidoreductase (SQR) catalyzes the two-electron oxidation of sodium sulfide (Na2S) into sulfane sulfur (S(0)) when provided flavin adenine dinucleotide and a water-soluble quinone acceptor: [SQR] (Mus musculus) PubMed

 18719.

The binding of NCKX2 Na(+)/Ca(2+)-K(+) exchanger with potassium and calcium ions is accomplished via Asp 575 and 548, respectively: [NCKX2] (Mus musculus) PubMed

 18720.

Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase in complex with a non-carbohydrate-based inhibitor, 2-(cyclohexylamino)ethanesulfonic acid, has been presented. [NanI] (Mus musculus) PubMed

 18721.

these results suggest that Rad26 exists as a dimer and provide crucial insight into how Rad3 is recruited and incorporated into the Rad3-Rad26 DNA repair complex. (Mus musculus) PubMed

 18722.

pFATP1 played an important role in porcine intramuscular preadipocytes proliferation and differentiation[FATP1] (Mus musculus) PubMed

 18723.

ZmWRKY4 might play a critical role in either regulating the ZmSOD4 and ZmcAPX expression or cooperating with them in response to stress and phytohormone [ZmWRKY4] (Mus musculus) PubMed

 18724.

These data demonstrate that Rab5b is transported from the parasite cytosol to the tubovesicular network together with N-myristoylated adenylate kinase 2 via an uncharacterized membrane-trafficking pathway.[Rab5b, adenylate kinase 2] (Mus musculus) PubMed

 18725.

ClbM responds to sodium, potassium, and rubidium ion gradients, while also having substantial transport activity in the absence of alkali cations [ClbM] (Mus musculus) PubMed

 18726.

YphC and YsxC bind specifically to the two immature particles, suggesting that they represent either on-pathway intermediates or that their structure has not significantly diverged from that of the actual substrate.[YphC, YsxC] (Mus musculus) PubMed

 18727.

The formation of PCNA tool belts and Rev1 bridges and the ability of these complexes to change architectures are likely means of facilitating selection of the appropriate non-classical polymerase and polymerase-switching events.[PCNA, Dna polymerase eta] (Mus musculus) PubMed

 18728.

Pol epsilon participates in short-patch base excision repair and ribonucleotide excision repair.[DNA polymerase epsilon] (Mus musculus) PubMed

 18729.

PfDHHC9 plays a role in the production of gametocytes in P. falciparum, perhaps because its substrate, or set of substrates, is required or only present in gametocytes. [PfDHHC9] (Mus musculus) PubMed

 18730.

following RNaseH2 cleavage, the combined activities of polymerase B (PolB), flap endonuclease (Fen1), and DNA ligase are required to complete ribonucleotide processing. PolB formed a ribonucleotide-containing flap by strand displacement synthesis that was cleaved by Fen1, and DNA ligase sealed the nick for complete repair. (Mus musculus) PubMed

 18731.

C-terminal domain of Ctp1 is required for both efficient clipping and resection of double-strand breaks by Mre11-Rad50-Nbs1 and these activities are mechanistically similar.[Ctp1, Mre11] (Mus musculus) PubMed

 18732.

We suggest that BGAL1 may be involved in the degradation of starch, which affects TAG accumulation in nitrogen-starved C. reinhardtii (Mus musculus) PubMed

 18733.

Chd1 responds to the presence of a bound protein on both entry and exit sides of the nucleosome.[CHD1] (Mus musculus) PubMed

 18734.

Sen1 plays a more direct role than Rad26 in transcription coupled DNA repair.[Sen1, Rad26] (Mus musculus) PubMed

 18735.

Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1. (Mus musculus) PubMed

 18736.

MazF acts as a prime effector during harsh stress that potentially introduces translational heterogeneity within a bacterial population thereby stimulating persister cell formation.[MazF] (Mus musculus) PubMed

 18737.

Rifampicin resistance mutations in the rpoB gene in Mycobacterium tuberculosis clinical isolates from Pakistan [rpob] (Mus musculus) PubMed

 18738.

These results suggest that staphylococcal superantigen-like protein 10 has two responsible sequences for the binding to prothrombin. [staphylococcal superantigen-like protein 10] (Mus musculus) PubMed

 18739.

Results strongly suggest that stress-induced eIF2alpha phosphorylation is a necessary event for the parasite life cycle under stressed conditions for survival. [eIF2A] (Mus musculus) PubMed

 18740.

These studies reveal a novel mechanism in which CYP2J2 and epoxyeicosatrienoic acids enhanced Akt1 nuclear translocation through interaction with AMPKalpha2beta2gamma1 and protect against cardiac hypertrophy.[CYP2J2] (Mus musculus) PubMed

 18741.

Analysis of H pylori strains from mice and from a chronically infected patient showed that CagY functions as an immune-sensitive regulator of Type IV Secretion System function. [CagY] (Mus musculus) PubMed

 18742.

Structural characterization of the heme-based oxygen sensor, AfGcHK, its interactions with the cognate response regulator, and their combined mechanism of action in a bacterial two-component signaling system have been described. [GcHK] (Mus musculus) PubMed

 18743.

this research also led to the establishment of a bacterial SuSy variant that is suitable for the recycling of UDP during glycosylation reactions. (Mus musculus) PubMed

 18744.

The crystal structure of maleylacetate reductase from Rhizobium sp. strain MTP-10005 has been reported that provides insights into the reaction mechanism of enzymes in its original family. [maleylacetate reductase] (Mus musculus) PubMed

 18745.

NusG domain interaction mediates autoinhibition and thermostability in Thermotoga maritima. [NusG] (Mus musculus) PubMed

 18746.

Characterization of the artemisinin-binding site of P. falciparum translationally controlled tumor protein (TCTP). [tctp] (Mus musculus) PubMed

 18747.

Kinetic modeling of photocurrents generated from ChR2 proteins with conservative mutations at these positions demonstrated that these residues contribute to cation selectivity (Val-86 and Asn-258), the transition between the two open states (Val-86), open channel stability (Mus musculus) PubMed

 18748.

A unique choanoflagellate enzyme rhodopsin exhibits light-dependent cyclic nucleotide phosphodiesterase activi (Mus musculus) PubMed

 18749.

ketoconazole binds in an orientation that disrupts the BC-loop regions at the P450 dimer interface and results in a CYP126A1 monomeric crystal form. Structural data also reveal that nitroaromatic ligands "moonlight" as substrates by displacing the CYP126A1 distal water but inhibit enzyme activity. (Mus musculus) PubMed

 18750.

A theoretical study on the reactivity of the Mo/Cu-containing carbon monoxide dehydrogenase with dihydrogen. (Mus musculus) PubMed

 18751.

beta-d-xylosidase/alpha-l-arabinofuranosidase from the ruminal anaerobic bacterium Selenomonas ruminantium (SXA) has potential utility in industrial processes such as production of fuel ethanol and other bioproducts. The optimized synthetic SXA gene was overexpressed in methylotrophic Pichia pastoris under the control of alcohol oxidase I (AOX1) promoter and secreted into the medium. (Mus musculus) PubMed

 18752.

Unique coenzyme binding mode of sn-glycerol-1-phosphate dehydrogenase (G1PDH) from Pyrobaculum calidifontis has been described. [G1PDH] (Mus musculus) PubMed

 18753.

NMR chemical shift perturbations demonstrate that a positively charged segment of MOAG-4 forms a transiently populated alpha-helix that interacts with the negatively charged C terminus of alpha-Syn. (Mus musculus) PubMed

 18754.

results show the 5'UTR 95DeltaG mutation of norA is important to acquire the high efflux activity phenotype in S. epidermidis; results also suggest mechanism involved in ethidium bromide efflux is due to the increment of transcription and/or translation of the norA gene [norA] (Mus musculus) PubMed

 18755.

Study investigating the conformational space of the N-terminal POTRA domain of anaOmp85 using using pulsed electron-electron double resonance [anaOmp85] (Mus musculus) PubMed

 18756.

The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism. [SLP] (Mus musculus) PubMed

 18757.

sigma70 binding and the elemental pause sequence together, but neither alone, produce a substantial transcription pause.[sigma70] (Mus musculus) PubMed

 18758.

Study used the nematode C elegans to test 7 de novo mutations in the human NALCN gene responsible for congenital contractures of the limbs and face with hypotonia and developmental delay syndrome. We found that all 7 variants were deleterious with dominantly inherited phenotypes. In C elegans, this mutation causes neuronal hyperactivity via a gain-of-function NALCN ion channel. [NALCN] (Mus musculus) PubMed

 18759.

the LIN-28/let-7/AKT/DAF-16 axis is a program that plays an important role in balancing reproduction and somatic maintenance.[Lin-28] (Mus musculus) PubMed

 18760.

fHbp thermoregulation requires sequences located in the translated region of the mono-cistronic fHbp mRNA (Mus musculus) PubMed

 18761.

The detection of positive selection operating on spA combined with frequent non-synonymous mutations, domain duplication and frequent intragenic recombination events represent important mechanisms acting in the evolutionary adaptive mechanism promoting spA genetic plasticity.[spA] (Mus musculus) PubMed

 18762.

P. berghei PAT appears to regulate exocytosis in two distinct populations of vesicles in two different life cycle forms rather than acting as pantothenic transporter during parasite transmission. (Mus musculus) PubMed

 18763.

BmNHR96 plays an important role in BV infection and this function probably actualized by affecting cellular cholesterol level [BmNHR96] (Mus musculus) PubMed

 18764.

CDPK3-dependent SCE1 phosphorylation is required to relieve its suppressive activity to potentiate egress. (Mus musculus) PubMed

 18765.

zfp-1 is required for the enhanced longevity observed during dietary restriction and on knockdown of Insulin/IGF-1-like signalling.[Zfp-1] (Mus musculus) PubMed

 18766.

The current state of structural studies, MD simulations and single-molecule FRET studies of GltPh that have provided insights into its transport mechanism is shown in this review. (Mus musculus) PubMed

 18767.

Lrp and SoxS were both found to be regulated post-transcriptionally.[Lrp, SoxS] (Mus musculus) PubMed

 18768.

Intersubunit distances in full-length, dimeric, bacterial phytochrome Agp1, as measured by pulsed electron-electron double resonance (PELDOR) between different spin label positions, remain unchanged upon photoconversion (Mus musculus) PubMed

 18769.

Pcc1 facilitates KEOPS dimerization in vitro.[Pcc1] (Mus musculus) PubMed

 18770.

The W181T mutant showed 10-fold reduced xanthine phosphoribosylation activity. [HGXPRTase] (Mus musculus) PubMed

 18771.

a genetic interaction between mnp-1 and cam-1, which encodes a Ror receptor tyrosine kinase required for some of the same cell migrations, is reported.[MNP-1, CAM-1] (Mus musculus) PubMed

 18772.

Suppressor of rid1 (SID1) encodes an INDETERMINATE DOMAIN (IDD) transcription factor, and both SID1 and Rice Indeterminate 1 (RID1) directly target the promoter regions of florigen genes: [SID1] (Mus musculus) PubMed

 18773.

Comparison reveals that Tcb2-calcium-induced conformational transition differs from the prototypical calcium sensor calmodulin, suggesting that the two proteins play distinct functional roles in Tetrahymena and likely have different mechanisms of target recognition. (Mus musculus) PubMed

 18774.

Based on these results, the authors propose that the carbohydrate phosphotransferase system permease BepA is directly implicated in Enterococcus faecium pathogenesis.[BepA] (Mus musculus) PubMed

 18775.

Here, solution X-ray scattering was used to provide insight into the overall structure and flexibility of the entire nonstructural protein 3 (NS3) and its recombinant helicase and protease domains for Dengue virus serotypes 2 and 4 in solution. [nonstructural protein 3] (Mus musculus) PubMed

 18776.

Oryza sativa Acyl-CoA-binding protein 2 (ACBP2) was found to display a higher binding affinity for unsaturated acyl-CoA esters than ACBP1. A difference between the two proteins is observed at helix 3 and is predicted to lead to different ligand-binding modes in terms of the shape of the binding pocket and the residues that are involved. [ACBP1, ACBP2] (Mus musculus) PubMed

 18777.

Here, the structure determination of family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis is reported, which has been refined to an R factor of 24.47% and an Rfree of 28.81% at 2.80 A resolution. [family B DNA polymerase] (Mus musculus) PubMed

 18778.

Here, solution X-ray scattering was used to provide insight into the overall structure and flexibility of the entire nonstructural protein 3 (NS3) and its recombinant helicase and protease domains for Dengue virus serotypes 2 and 4 in solution. [nonstructural protein 3] (Mus musculus) PubMed

 18779.

Crystal structures of Lactobacillus buchneri isoleucine 2-epimerase, a novel branched-chain amino-acid racemase, were determined for the enzyme in the apo form, in complex with pyridoxal 5'-phosphate (PLP), in complex with N-(5'-phosphopyridoxyl)-L-isoleucine (PLP-L-Ile) and in complex with N-(5'-phosphopyridoxyl)-D-allo-isoleucine (PLP-D-allo-Ile) at resolutions of 2.77, 1.94, 2.65 and 2.12 A. [isoleucine 2-epimerase ] (Mus musculus) PubMed

 18780.

KirrelL, a primary mesenchyme cell (PMC)-specific, Ig domain-containing transmembrane protein, is essential for PMC fusion, probably by mediating filopodial adhesions that are a pre-requisite for subsequent membrane fusion.[KirrelL] (Mus musculus) PubMed

 18781.

preliminary analysis of, high resolution X-ray diffraction data collected for the co-crystals of B. licheniformis, Gamma glutamyl transpeptidase, with its inhibitor, Acivicin. Crystals belong to the orthorhombic space group P212121 and diffract X-ray to 1.45 A resolution. (Mus musculus) PubMed

 18782.

Results show that the activity of sporulation master regulator Spo0A increases with decreasing cellular growth rate of Bacillus subtilis. [Spo0A] (Mus musculus) PubMed

 18783.

Three Cas proteins (Cas6f, Cas7fv, Cas5fv) and mature CRISPR RNAs were shown to be required for the assembly of an interference complex termed Cascade. [Cas6f];[Cas7fv];[Cas5fv] (Mus musculus) PubMed

 18784.

Secretion of functional formate dehydrogenase in Pichia pastoris. (Mus musculus) PubMed

 18785.

neuronal expression of lin-11 involves multiple transcription factor regulators and regulatory modules some of which have diverged in Caenorhabditis nematodes.[Lin-11] (Mus musculus) PubMed

 18786.

Study shows that constitutive endocytosis of M78 is mediated via the cytoplasmic C-tail and that endocytosis is essential for M78 function. [M78] (Mus musculus) PubMed

 18787.

TdtA belongs to a new type of Integrative and Conjugative Element which promotes the generalized and efficient transfer of genetic traits that could facilitate its co-selection among bacterial populations [TdtA] (Mus musculus) PubMed

 18788.

Structural basis of outer dynein arm intraflagellar transport by the transport adaptor protein ODA16 and the intraflagellar transport protein IFT46. (Mus musculus) PubMed

 18789.

Analysis of the key structural features and surface residues involved in DNA binding and catalysis by Sda1 nuclease (Sda1) (Mus musculus) PubMed

 18790.

The present work sheds new light on the molecular mechanism by which G4-unwinding helicase Pif1p resolves physiological G4/duplex DNA structures in cells.[Pif1] (Mus musculus) PubMed

 18791.

Study showed that the DNA-binding property of ParA is also critical for the establishment of a stable gradient of ParA across the cell, which sets up the translocation directionality well before DNA replication and segregation are initiated [ParA, C. crescentus CJW3367] (Mus musculus) PubMed

 18792.

WipA can thereby transition from a homodimeric state to a heterodimeric state in which the coiled-coil region of WipA is engaged in a protein-protein interaction with a tyrosine-phosphorylated host target. (Mus musculus) PubMed

 18793.

Study analyzed the oligomeric state of different soluble and full-length FeoB constructs; showed that the full-length protein is predominantly monomeric, whereas dimers and trimers are formed to a small percentage; presented a new crystal structure of the cytosolic GTPase domain of FeoB from Escherichia coli BL21 [FeoB] (Mus musculus) PubMed

 18794.

Crystal structures of holoUbiD reveal a relatively open active site potentially occluded from solvent through domain motion. The presence of a prenylated Flavin Mononucleotide sulfite-adduct in one of the UbiD crystal structures confirms oxidative maturation does occur at ambient pH on a slow time scale. (Mus musculus) PubMed

 18795.

the conserved proteins Rif1 and Exo1 are critical for survival and evolution of cells with lost telomeres.[Rif1, Exo1] (Mus musculus) PubMed

 18796.

Findings indicate that epsA is a positive regulator of exopolysaccharide (EPS) production and that EPS production can be manipulated by altering its expression. [epsA] (Mus musculus) PubMed

 18797.

cAMP dependent protein kinase A (PKA) is a key intracellular factor mediating SHH signaling through regulation of GLI3 processing.[PKA] (Mus musculus) PubMed

 18798.

formation of a Snf1-Mec1-Atg1 module on mitochondria governs energy deprivation-induced autophagy by regulating mitochondrial respiration.[Snf1, Mec1, Atg1] (Mus musculus) PubMed

 18799.

FUG1 represents a novel class of fungal transcription factors or genes otherwise involved in signal transduction.[FUG1] (Mus musculus) PubMed

 18800.

The structure of S. thermophila StCBM64C revealed an untwisted, flat, carbohydrate-binding interface comprising the side chains of four tryptophan residues in a co-planar linear arrangement. Significantly, two highly conserved asparagine side chains, each one located between two tryptophan residues, are critical to insoluble and soluble glucan recognition but not to bind xyloglucan. [StCBM64C] (Mus musculus) PubMed

 18801.

This study used Candida antarctica lipase B (CALB) as a test system to demonstrate the effectiveness of the computational prediction of (non)substrates. A novel molecular mechanics score function for CALB substrate identification derived from the near-attack conformation was used to evaluate the possibility of chemical transformation. [lipase B] (Mus musculus) PubMed

 18802.

a 3.9-A structure of Saccharomyces cerevisiae origin recognition complex-Cdc6-Cdt1-Mcm2-7 on DNA, is reported.[Cdc6, Cdt1] (Mus musculus) PubMed

 18803.

structures of the yeast MCM hexamer and Cdt1-MCM heptamer from Saccharomyces cerevisiae, were examined.[Cdt1] (Mus musculus) PubMed

 18804.

PPDK1 and LEA1 role in response to salt stress [PPDK1] [LEA1] (Mus musculus) PubMed

 18805.

MCK-2 is an atypical viral chemokine consisting of a CC chemokine domain and a unique non-chemokine domain, both of which bind GAGs and are critical for GAG-dependent oligomerization of the full-length protein. (Mus musculus) PubMed

 18806.

GIF2 plays important roles in the regulation of grain filling and starch biosynthesis during caryopsis development, and that it has been preserved during selection throughout domestication of modern rice.[GIF2] (Mus musculus) PubMed

 18807.

these results provide insights into the role of Vdpf in melanized microsclerotia formation, conidia production and pathogenicity.[Vdpf] (Mus musculus) PubMed

 18808.

Thrombin cleavage sites were mapped to the Duffy binding-like delta1 (DBLdelta1) domain and interdomains 1 and 2 in the PfEMP1 of the parasite line IT4var19.[PfEMP1] (Mus musculus) PubMed

 18809.

Taken together, these data suggest that TgAMA1-TgRON2 interaction at the moving junction protects TgAMA1 molecules that are actively engaged in host cell penetration from rhomboid-mediated cleavage and generates an outside-in signal that leads to dephosphorylation of the TgAMA1 cytosolic tail.[AMA1, RON2] (Mus musculus) PubMed

 18810.

Tandem affinity purification, followed by mass spectrometry and yeast two-hybrid analysis, verified that protein phosphatase 2A catalytic subunit 1 (PP2Ac1) is a subunit of the striatin-interacting phosphatase and kinase complex.[PP2Ac1] (Mus musculus) PubMed

 18811.

Results suggest that aKMT may serve a role in maintaining the methylation status of cellular proteins required for the efficient growth of the organism under certain non-optimal conditions. Its crystal structure of in complex with S-adenosyl-l-methionine or S-adenosyl homocysteine reveals that the protein consists of four alpha helices and seven beta sheets, lacking a substrate recognition domain. [KMT] (Mus musculus) PubMed

 18812.

Hypodermin A (HA) overexpression resulted in significantly prolonged skin allograft survival in mice. Histologic changes in the skin allografts paralleled the gross appearance of rejection. HA significantly reduced the content of complement C3 and C9 in HA skin allografts. The expressions of CD4, B7-2, and MHC class II were all significantly suppressed in HA skin allografts compared with the control group. [hypodermin A] (Mus musculus) PubMed

 18813.

V67L Mutation Fills an Internal Cavity To Stabilize RecA Mtu Intein [RecA] (Mus musculus) PubMed

 18814.

TrmJ is a tRNA:Cm32/Um32/Am32 methyltransferase involved in translational fidelity and the oxidative stress response. [TrmJ] (Mus musculus) PubMed

 18815.

Caenorhabditis elegans RNase, REGE-1, related to MCPIP1/Zc3h12a/Regnase-1, a key regulator of mammalian innate immunity, promotes accumulation of body fat.[REGE-1] (Mus musculus) PubMed

 18816.

This study reveals that the apicoplast-located type II fatty acid synthesis pathway and a plant-like glycerol 3-phosphate acyltransferase, ATS1, which are primarily used to generate plastid galactolipids in plants and algae, instead generate bulk phospholipids for membrane biogenesis in T. gondii (Mus musculus) PubMed

 18817.

Data show that knockdown of nuclear speckle-related protein 70 (NSrp70) resulted in dramatic reduction in the length of developing tadpoles and mild to severe malformation in embryos: [NSrp70] (Mus musculus) PubMed

 18818.

Ammonia accumulation in the host environment by the pathogen under acidic pH may be a regulatory cue for pacC activation, towards the accumulation of secondary metabolites, such as patulin.[PacC] (Mus musculus) PubMed

 18819.

analysis of mutants that map to two areas in the structure of DsbB, one located between the two first transmembrane segments where the quinone ring binds and the other located in the second periplasmic loop of DsbB, which interacts with DsbA [DsbB] (Mus musculus) PubMed

 18820.

Crystal structure of the ADP-ribosylating component of binary enterotoxin [BEC] gives a detailed picture of interactions between BEC and NADH. [BEC] (Mus musculus) PubMed

 18821.

mapping of the powdery mildew resistance gene Pm58 [Pm58] (Mus musculus) PubMed

 18822.

Results identifies MTRAP as a novel factor essential for mosquito transmission of plasmodium berghei. [MTRAP] (Mus musculus) PubMed

 18823.

two TCP (TEOSINTE BRANCHED/CYCLOIDEA/PROLIFERATING CELL FACTOR) transcription factors of Malus x domestica as binding partners of the P. mali SAP11-like effector ATP_00189.[TCP24, TCP25] (Mus musculus) PubMed

 18824.

The appressorium morphology of the null mutants is normal, but they exhibit delayed development during the infection process on maize leaves and roots, showing that Cgfl has a role in virulence.[Cgfl] (Mus musculus) PubMed

 18825.

electron cryo-microscopy structure of ArfA and RF2 in complex with the 70S ribosome bound to a nonstop mRNA [ArfA and RF2] (Mus musculus) PubMed

 18826.

Using genetic and biochemical techniques, this study determined the trans-Aconitic acid (TAA) biosynthetic gene operon consisting of tbrA and tbrB genes in strain CT-43 as well as the isomerism and transportation processes mediated by aconitate isomerase TbrA and TAA transporter TbrB in the TAA biosynthesis of B. thuringiensis. [TbrA , TbrB] (Mus musculus) PubMed

 18827.

Study examined the differences between gonococcal AmpG and meningococcal AmpG and characterize peptidoglycan (PG) fragment release in N. sicca and N. mucosa. Replacement of meningococcal ampG with gonococcal ampG resulted in increased PG fragment release. Results suggest that N. gonorrhoeae has evolved to increase the amounts of toxic PG fragments released by reducing its PG recycling efficiency. [AmpG] (Mus musculus) PubMed

 18828.

LcpA has a very important role in cell wall biogenesis and integrity, as it is presumably responsible for the ligation of arabinogalactan to peptidoglycan [LcpA] (Mus musculus) PubMed

 18829.

Lipids stabilize the inward-open conformation of LmrP. [LmrP] (Mus musculus) PubMed

 18830.

Study examined the differences between gonococcal AmpG and meningococcal AmpG and characterize peptidoglycan (PG) fragment release in N. sicca and N. mucosa. Replacement of meningococcal ampG with gonococcal ampG resulted in increased PG fragment release. Results suggest that N. gonorrhoeae has evolved to increase the amounts of toxic PG fragments released by reducing its PG recycling efficiency. [AmpG] (Mus musculus) PubMed

 18831.

The results exemplify how stress-induced inactivation of TIF-IA and long non-coding RNA -dependent changes of chromatin structure ensure repression of ribosomal RNA synthesis in response to thermo-stress.[PAPAS] (Mus musculus) PubMed

 18832.

In the absence of ubiquitin or substrate liposomes, the overall structure of the C-terminal domain is in good agreement with crystallographic models derived from ExoU in complex with its chaperone, SpcU. Significant conformational changes are observed throughout the domain in the presence of ubiquitin and liposomes combined that are not observed with either liposomes or ubiquitin alone. [ExoU] (Mus musculus) PubMed

 18833.

he crystal structure of LdtMt2 at 1.54 A resolution with this fragment bound revealed that the protein adopts a closed conformation that shields the thioester bond from the solvent, which is in line with the high stability of this dead-end complex observed also in biochemical assays. (Mus musculus) PubMed

 18834.

Pch2 also possesses a positive action on Hop1 promoting its phosphorylation and its proper distribution on unsynapsed chromosome axes.[Hop1, Pch2] (Mus musculus) PubMed

 18835.

These data fortify sequential Top1 cleavage as the mechanism for ribonucleotide-dependent deletions and provide new insight into the component steps of this process.[Top1] (Mus musculus) PubMed

 18836.

the base-pairing of Rnt1p substrates encodes reactivity determinants that permit both constitutive processing of non-coding RNA while limiting the rate of mRNA degradation.[Rnt1p] (Mus musculus) PubMed

 18837.

crystal structures of Saccharomyces cerevisiae and Chaetomium thermophilum Brr2-Jab1 complexes, are reported demonstrating that Jab1-based inhibition of Brr2 presumably takes effect in all eukaryotes but is implemented via organism-specific molecular contacts.[Brr2] (Mus musculus) PubMed

 18838.

ere we show that the the trans-activation of frameshifting is carried out by a protein complex composed of nsp1beta and a cellular poly(C) binding protein (PCBP). (Mus musculus) PubMed

 18839.

Data demonstrated the effect of the yapA gene upon radial growth, conidial development, pigmentation, processing of fission division, and stress response in T. marneffei. [tapA] (Mus musculus) PubMed

 18840.

Results identify Spot 20 which expression is regulated under cold and salt stresses in wheat leaves and suggest that it possibly plays an important role in conferring cold tolerance in wheat. (Mus musculus) PubMed

 18841.

This murine cytomegalovirus (MCMV)-encoded protein, m12, restrains NK cell effector function by directly engaging the inhibitory NKR-P1B receptor. However, m12 also interacts with the activating NKR-P1A/C receptors to counterbalance m12 decoy function. Structural analyses reveal that m12 sequesters a large NKR-P1 surface area via a "polar claw" mechanism. [m12] (Mus musculus) PubMed

 18842.

These studies of Giardia lamblia Rac show that it regulates encystation at several levels, and the findings support its coordinating role as a regulator of cyst wall protein trafficking and secretion.[Rac] (Mus musculus) PubMed

 18843.

A newly identified protein, CtaM, is found to be required for the function of QoxABCD.[CtaM, QoxABCD] (Mus musculus) PubMed

 18844.

The results do not support EBP2 as a ligand for invasion of Duffy-negative blood cells, but instead, EBP2 may represent a novel ligand for an alternate invasion pathway of Duffy-positive reticulocytes.[EBP2] (Mus musculus) PubMed

 18845.

This study reports transient kinetics and product analysis of the dechlorinating flavin-dependent monooxygenase, HadA, from the aerobic organism Ralstonia pickettii DTP0602, identifying several mechanistic properties that differ from other enzymes in the same class. [HadA] (Mus musculus) PubMed

 18846.

our studies provide new insights into how MoDnm1 interacts with its partner proteins to mediate peroxisomal and mitochondrial functions and how such regulatory events may link to differentiation and pathogenicity in the rice blast fungus. (Mus musculus) PubMed

 18847.

The solved crystal structure of T-type Phycobiliprotein Lyase PhiCpeT at 1.8-A resolution revealed that the protein adopts a similar fold as the cyanobacterial T-type lyase CpcT from Nostoc sp. PCC7120 but overall is more compact and smaller [T-type Phycobiliprotein Lyase ]. (Mus musculus) PubMed

 18848.

Grctm6 protein is not only expressed in Biomphalaria glabrata hemolymph, but that it also has a role in modulating the number of Schistosoma mansoni cercariae released by infected snails, making it a possible target for the biological control of schistosomiasis. (Mus musculus) PubMed

 18849.

Structural Insights into the Methylation of C1402 in 16S rRNA by Methyltransferase RsmI [RsmI] (Mus musculus) PubMed

 18850.

Mfd is required to maintain bacterial genome integrity in a NER-independent but RecBC-dependent pathway [Mfd][RecBC] (Mus musculus) PubMed

 18851.

Data, including data on the crystal structure of Hip1 to 2.6 A resolution, suggest that Hip1 exhibits a two-domain structure, one of which contains the catalytic residues that are the signature of a serine protease; surprisingly, a threonine is located within the active site close enough to hydrogen bond with the catalytic residues Asp463 and His490. [Hip1, serine protease/hydrolase important for pathogenesis] (Mus musculus) PubMed

 18852.

Wee1 and Cdc25 undergo dramatic cell cycle-dependent changes in phosphorylation that are dependent upon PP2A associated with the regulatory subunit Pab1.[Wee1, Cdc25, PP2A] (Mus musculus) PubMed

 18853.

POMP10, a Mitochondrial Outer Membrane Protein of the early diverging protozoan Trypanosoma brucei, is signal-anchored. Transgenic cells expressing variants of POMP10 fused to GFP demonstrate that the N-terminal membrane-spanning domain flanked by a few positively charged or neutral residues is both necessary and sufficient for mitochondrial targeting. [POMP10] (Mus musculus) PubMed

 18854.

H. capsulatum SREBP is critical for hypoxic adaptation and is required for H. capsulatum virulence [Srb1] (Mus musculus) PubMed

 18855.

OmpA-like protein of T. forsythia contains O-linked sugar chains that can mediate interactions with specific lectins [OmpA] (Mus musculus) PubMed

 18856.

E2FL1, a meiosis-specific E2F transcription factor gene, was identified in the model ciliate Tetrahymena thermophile.[E2fl1] (Mus musculus) PubMed

 18857.

CETP modulates the distribution of spingosine-1-phosphate among lipoproteins, which affects the bioactivities of S1P. (Mus musculus) PubMed

 18858.

These findings reveal that H-NS can systematically modulate the frequency of transposon insertions.[H-NS] (Mus musculus) PubMed

 18859.

Here is presented the crystal structure of exo-beta-d-glucosaminidase in complex with glucosamine at 1.27 A resolution. [exo-beta-d-glucosaminidase] (Mus musculus) PubMed

 18860.

Here is presented the crystal structure of exo-beta-d-glucosaminidase in complex with glucosamine at 1.27 A resolution. [exo-beta-d-glucosaminidase] (Mus musculus) PubMed

 18861.

These structures have captured for the first time a DNA glycosylase scanning the genome for a damaged base in the very first stage of lesion recognition and the base extrusion pathway. The mode of interaction observed here has suggested a common lesion-scanning mechanism across the entire helix-hairpin-helix superfamily to which MutY belongs. [MutY] (Mus musculus) PubMed

 18862.

the data indicate that the wheat COP9 subunit 5-like gene acts as a negative regulator of wheat leaf rust resistance.[TaCSN5] (Mus musculus) PubMed

 18863.

Overexpression of a dominant negative mutant of Rab35 reduced phagocytic cup formation and thereby reduced red blood cells (RBC) internalization, suggesting a potential role of the Rab GTPase in the cup formation. Furthermore, a phagosomal maturation assay showed that the activated form of Rab35 significantly increased the rate of RBC degradation. [GTPase Rab35 ] (Mus musculus) PubMed

 18864.

TOP2 and BAF cooperate to recruit pluripotency factors, which explains some of the instructive roles of BAF complexes.[BAF] (Mus musculus) PubMed

 18865.

DNA Polymerase Dynamics at a Bacterial Replisome in Live Cells [PolC] (Mus musculus) PubMed

 18866.

African swine fever virus PolX has one unique 5'-phosphate (5'-P) binding pocket, which can favor the productive catalytic complex assembly and enhance the dGTP misincorporation efficiency.[PolX] (Mus musculus) PubMed

 18867.

A role for the Rht-B1c protein in protective mechanisms and tolerance of the photosynthetic apparatus in wheat plants exposed to heavy metals stress. [Rht-B1c] (Mus musculus) PubMed

 18868.

Molecular cloning and characteristic features of a novel extracellular tyrosinase from Aspergillus niger PA2 have been described. [tyrosinase] (Mus musculus) PubMed

 18869.

These results suggest that expression of COX2 and lncRNACOX2 increased with the progression of liver fibrosis.[lncRNA-COX-2] (Mus musculus) PubMed

 18870.

Conserved residues in Ycf54 are required for protochlorophyllide formation in Synechocystis sp. PCC 6803. [Ycf54] (Mus musculus) PubMed

 18871.

Membrane-derived vesicle production by group A streptococcus strains varied in a manner dependent on an intact two-component system, CovRS, with membrane-derived vesicle production negatively regulated by the system.[CovRS] (Mus musculus) PubMed

 18872.

Hrr25 mediates exit from meiosis II by activating pathways that trigger the destruction of M-phase-promoting kinases.[Hrr25] (Mus musculus) PubMed

 18873.

analysis of catalytic properties, ligand-binding profiles, and inhibition of enzymatic activity of C. albicans CYP51 by clinical antifungal drugs that are used systemically and topically [CYP51] (Mus musculus) PubMed

 18874.

Two FgLEU2 genes with different roles in leucine biosynthesis and infection-related morphogenesis in Fusarium graminearum have been described. [LEU2] (Mus musculus) PubMed

 18875.

The results predict a role for AnAFP during slow growth, allorecognition, asexual development and nutrient recycling of A. niger and propose that it interacts with the autophagic machinery to enable these processes. [AnAFP] (Mus musculus) PubMed

 18876.

Binding affinity of Ler to the LEE5 promoter DNA is about 40 folds greater than that of H-NS.Ler binding removed H-NS bound to the same stretch of DNA on LEE5 promoter resulting in a derepression.H-NS specifically represses LEE5 promoter activity and Ler alleviates the repression by H-NS. [Ler] (Mus musculus) PubMed

 18877.

Recombinant expression of inactivated RpdA shows that loss of catalytic activity is responsible for the lethal phenotype of Aspergillus RpdA null mutants.[RpdA] (Mus musculus) PubMed

 18878.

This NS5(non-structural protein- 5 (NS5)) ELISA can also be used to distinguish between primary and secondary dengue fever on the basis of IgM/IgG ratios. Further studies with larger sample sizes and different DENV serotypes are required to validate the ELISA. (Mus musculus) PubMed

 18879.

These structural analyses suggest that the photoconversion between the red-absorbing and the far-red-absorbing states in the full-length XccBphP may involve changes in the relative positioning of the output module.[XccBphP] (Mus musculus) PubMed

 18880.

the role of SlyA in transcriptional modulation of a range of genes associated with bacterial virulence, is reported.[SlyA] (Mus musculus) PubMed

 18881.

grapefruit cyclophilin promotes a conformational change in AvrGf2, thereby triggering the resistance response.[AvrGF2] (Mus musculus) PubMed

 18882.

single-particle cryo-electron microscopy (cryo-EM) was used to determine a near-atomic-resolution structure of the Caenorhabditis elegans separase-securin complex.[Securin] (Mus musculus) PubMed

 18883.

This study identified novel pathways dependent on RpoS, the master regulator of stationary phase, that further strengthen the outer membrane permeability barrier during nutrient limitation, circumventing the need for efflux pumps.[RpoS] (Mus musculus) PubMed

 18884.

Instant growth cessation and cell death is observed upon co-expression of the two bacteriophage SPP1 holin-like, gp24.1 and gp26. in B. subtilis . [gp24.1, gp26] (Mus musculus) PubMed

 18885.

Tor1 and casein kinase 2 (CK2) kinases regulate a rapid switch between a productive and a non-productive pre-rRNA processing pathways in yeast.[Tor1, CK2] (Mus musculus) PubMed

 18886.

Disrupting the YscU-YscP interaction by introducing point mutations at the interaction interface significantly reduced the secretion of effector proteins and HeLa cell cytotoxicity. [YscU, YscP] (Mus musculus) PubMed

 18887.

The authors have determined the structure of the activated Enterococcus faecium LiaR protein at 3.2A resolution and, in combination with solution studies, show that the activation of LiaR induces the formation of a LiaR dimer that increases LiaR affinity at least 40-fold for the extended regulatory regions upstream of the liaFSR and liaXYZ operons. (Mus musculus) PubMed

 18888.

CSL proteins play conserved roles in regulating cell-cycle progression, and they could guide experiments into mitotic CSL functions in mammals.[CSL] (Mus musculus) PubMed

 18889.

Complementation of the hrpL mutant with promoter deletion constructs of the hrpL gene and promoter activity analyses using various lengths of the hrpL promoter fused to a promoter-less green fluorescent protein (gfp) reporter gene delineated the upstream region for HrpS binding.[HrpS, hrpL, RpoN] (Mus musculus) PubMed

 18890.

the role of the N-terminal extension of the yeast S31 protein, was studied.[Rps31] (Mus musculus) PubMed

 18891.

FabF1 is a functional replacement for FabB; Suppression of FabB is caused by a TGTTTT deletion in the region upstream of the fabF1 gene, resulting in enhanced FabF1 production. [FabF1] (Mus musculus) PubMed

 18892.

we mapped the Snn3 locus in the SHA3/CBRD x Naxos population and identified it as a major determinant of susceptibility to Septoria nodorum blotch both under natural field infection at the adult stage and single spore isolate inoculations of seedlings [Snn3] (Mus musculus) PubMed

 18893.

ApB73 is a conserved and important virulence factor of U. maydis.[ApB73] (Mus musculus) PubMed

 18894.

RNase H1 activity of RnhA or RnhC is essential for growth whereas RnhB and RnhA guard against killing by hydrogen peroxide in stationary phase. [RnhC] (Mus musculus) PubMed

 18895.

The quinoprotein ethanol dehydrogenase ExaF contributes to ethanol metabolism when La3+ is present, expanding the role of lanthanides to multicarbon metabolism. [ExaF] (Mus musculus) PubMed

 18896.

The polar landmark protein HubP is involved in the regulation of flagellar biogenesis. Deletion of hubP increased the number of flagella without increasing the amount of pole-localizing FlhF, indicating that the number of flagella is not determined solely by the absolute amount of pole-localizing FlhF. Cytoplasmic FlhG and HubP-anchored polar FlhG negatively regulate flagellar formation [HubP; FlhG] (Mus musculus) PubMed

 18897.

data illustrate a stop-codon surrogate mechanism for ArfA in facilitating the termination of non-stop ribosomal complexes by RF2 [Arf2 and RF2] (Mus musculus) PubMed

 18898.

cryo-electron microscopy reconstruction of the Escherichia coli 70S ribosome stalled on a truncated mRNA in the presence of ArfA and RF2 [ArfA and RF2] (Mus musculus) PubMed

 18899.

These results confirm that ArlRS and MgrA constitute a regulatory cascade, and that they control expression of a number of genes important for virulence, including those for eight large surface proteins (Mus musculus) PubMed

 18900.

pre-60S ribosomal particles belong to a specific late stage of cytoplasmic pre-60S maturation in which ribosomal proteins uL16, uL10, uL11, eL40 and eL41 are deficient, but ribosome assembly factors Nmd3, Lsg1, Tif6 and Reh1 are present.[Nmd3, Lsg1, Tif6, Reh1] (Mus musculus) PubMed

 18901.

Combining these results with small-angle X-ray scattering data for the complex of TRN-SR2 with truncated integrase, we propose a molecular model of the complex. We speculate that nuclear import of the PIC may proceed concurrently with the normal nuclear transport. (Mus musculus) PubMed

 18902.

miR319 is involved in rice plant height; overexpression of miR319 causes shortening [miR319] (Mus musculus) PubMed

 18903.

The authors also discovered that, despite its 66% sequence identity to human PP1alpha, the catalytic domain of PPZ1 contains novel structural elements that are not present in PP1alpha.[PPZ1] (Mus musculus) PubMed

 18904.

Data suggest that Cry41Aa/parasporin-3 exhibits pore-forming activity rather than apoptosis-inducing activity against human cancer cell line HepG2 (but not HeLa cell line); an exposed loop region believed to be involved in receptor binding of insecticidal Cry endotoxins is important for cytotoxic activity of Cry41Aa against HepG2 cells. [Cry41Aa, parasporin-3 protein] (Mus musculus) PubMed

 18905.

MJ0796 protein has nucleotide binding domains and not all the nucleotide binding sites of it nucleotide-binding domains are occupied by ATP. [MJ0796] (Mus musculus) PubMed

 18906.

Cig2 function promotes constitutive fusion between the Coxiella-containing vacuole and autophagosomes generated by selective autophagy.[Cig2] (Mus musculus) PubMed

 18907.

This study characterizes the enzymatic specificity of the Eng1 and Exg8 proteins and shows that Exg8 is an exo-beta1,3-glucanase and Eng1 is an endo-beta 1,3-glucanase. [Eng1, Exg8] (Mus musculus) PubMed

 18908.

Two distinct assembly states of the cysteine regulatory complex of Salmonella typhimurium are regulated by enzyme-substrate cognate pairs. [O-acetylserine sulfhydrylase] (Mus musculus) PubMed

 18909.

This study examined the ability of Rous Sarcoma Virus Integrase dimers to assemble two viral DNA molecules into intasomes containing Integrase tetramers in contrast to one possessing Integrase octamers. [Integrase] (Mus musculus) PubMed

 18910.

A dominant gain-of-function mutation in swsn-4, a component of SWI/SNF chromatin remodeling complexes, affects the PTH domain. The mutation only suppresses loss-of-function mutations that are overcome by LET- 23 overexpression, and only promotes a multivulval phenotype in conjunction with the dosage-sensitive let-23(sa62) allele, but not other hyperactivated signaling backgrounds. SW-SN4. (Mus musculus) PubMed

 18911.

SarA specifically binds regulatory small RNAs promoters.The SarA transcription factor reduces levels of Srn_3610_SprC RNA during S. aureus growth. [SarA] (Mus musculus) PubMed

 18912.

Results delineated the minimal fragment necessary for enzymatic activity and determined the structure of the active form of GtgE which shows that Cys45 interacts with His151 and Asp169 to form an active site. [GtgE] (Mus musculus) PubMed

 18913.

Cdk3 is necessary for the expression of many genes involved in early meiotic events.[Cdk3] (Mus musculus) PubMed

 18914.

OXA is of central importance for the biogenesis of the mitochondrial inner membrane.[OXA1] (Mus musculus) PubMed

 18915.

By using bacterial two-hybrid analysis and co-immunoprecipitation, we further show that the disordered L3-L4 loop is necessary to interact with TssK and that the L6-L7 loop mediates the interaction with TssE, whereas the TssM cytoplasmic loop binds the conserved groove of the TssL cytoplasmic domain.[TssL] (Mus musculus) PubMed

 18916.

The authors find here evidence that the targeting of SciP (TssL) to the membrane of Escherichia coli occurs co-translationally since signal elements in the N-terminal part of the SciP protein sequence are present.[SciP] (Mus musculus) PubMed

 18917.

These data show the interactions between the Type VI Secretion TssM cytoplasmic comain and the TssG baseplate component. (Mus musculus) PubMed

 18918.

Tanf_08375 and Tanf_08380 proteins are transporters for peptidoglycan amino sugar N-acetylmuramic acid. MurQ etherase (TfMurQ) involved in the metabolic conversion of MurNAc-6-phosphate (MurNAc-6-P) to GlcNAc-6-P [Tanf_08375; Tanf_08380; MurQ] (Mus musculus) PubMed

 18919.

VdNRS/ER is a functional enzyme in the biosynthesis of uridine diphosphate (UDP)-rhamnose, and further analysis has revealed that VdNRS/ER deletion strains are impaired in the colonization of tomato roots.[VdNRS/ER] (Mus musculus) PubMed

 18920.

the long terminal repeat-retrotransposon insertion in BoCYP704B1 hinders sporopollenin formation leading to male sterility [BoCYP704B1] (Mus musculus) PubMed

 18921.

Data suggest substrate specificity of AklB dioxygenase extends to 1,N(6)-alpha-hydroxypropanoadenine (HPA), an environmental mutagen; from molecular modeling of HPA/AlkB complex, R stereoisomer in equatorial conformation of HPA hydroxyl group is strongly preferred, while S stereoisomer is susceptible to AlkB-directed oxidative hydroxylation only when HPA adopts syn conformation around glycosidic bond. [AklB dioxygenase] (Mus musculus) PubMed

 18922.

Rbf Controls the Staphylococcus epidermidis Biofilm Phenotype by Negatively Regulating the icaADBC Repressor SarR. [Rbf, SarR] (Mus musculus) PubMed

 18923.

SpxA1 and SpxA2 enhance the affinity of RNAP for spxA2 promoter DNA and that this activity is sensitive to reductant. [SpxA1, SpxA2] (Mus musculus) PubMed

 18924.

The RDV capsid protein P2 binds OsIAA10, blocking the interaction between OsIAA10 and OsTIR1 and inhibiting 26S proteasome-mediated OsIAA10 degradation. (Mus musculus) PubMed

 18925.

Data suggest that BifR is a metalloprotease that represses biofilm formation via down-regulation of expression of genes involved in biofilm formation; inactivation of BifR results in enhanced biofilm formation; BifR exhibits disulfide-linked dimer-of-dimers structure depending on cellular redox state. [BifR, metalloprotease BifR] (Mus musculus) PubMed

 18926.

tubercidin-resistance protein (TRP) is associated with Tubercidin resistance in Leishmania [TRP] (Mus musculus) PubMed

 18927.

These results indicate that miR-29a regulates stearoyl-CoA desaturase levels by binding to its 3' UTR, and this interaction affects saturated fatty acid stress induction and insulin and lipid accumulation in serum. [miR-29a] (Mus musculus) PubMed

 18928.

H7 hemagglutinin strongly affects the frequency of infection following ocular inoculation in the mouse model, regardless of the neuraminidase with which it is paired or the lineage from which it is derived. (Mus musculus) PubMed

 18929.

T238A substitution in the T-loop reduces the kinase activity of Cdc5, the only PLK in Saccharomyces cerevisiae, with minor effect on cell growth in unperturbed conditions.[Cdc5] (Mus musculus) PubMed

 18930.

Data suggest that, having evolved separately from a common malate dehydrogenase ancestor, two enzymes (Ldh from Cryptosporidium parvum and Ldh from Plasmodium falciparum) exhibit several important structural differences, notably a five-amino acid insertion in the active site loop of P. falciparum Ldh. [Ldh, lactate dehydrogenase] (Mus musculus) PubMed

 18931.

Data suggest that, having evolved separately from a common malate dehydrogenase ancestor, two enzymes (Ldh from Cryptosporidium parvum and Ldh from Plasmodium falciparum) exhibit several important structural differences, notably a five-amino acid insertion in the active site loop of P. falciparum Ldh. [Ldh, lactate dehydrogenase] (Mus musculus) PubMed

 18932.

Taken together, these results show that Shu1 undergoes rapid hemin-induced internalization from the cell surface to the vacuolar membrane and that the transporter Abc3 participates in the mobilization of stored heme from the vacuole to the cytosol. (Mus musculus) PubMed

 18933.

We also demonstrate that recombinant TcBDF3 is able to bind to these inhibitors in vitro in a concentration-dependant manner. In parallel, the overexpression of a mutated version of TcBDF3 negatively affects growth of epimastigotes. Recent results, including the ones presented here, suggest that bromodomain inhibitors can be conceived as a new type of anti-parasitic drug against trypanosomiasis. (Mus musculus) PubMed

 18934.

Functional and structural characterization of a potent GH74 endo-xyloglucanase taking part in the first step of xyloglucan degradation has been presented. [GH74] (Mus musculus) PubMed

 18935.

Here, the authors demonstrate that spxA1, but not spxA2, is required for the oxidative stress response and pathogenesis.[spxA1, spxA2] (Mus musculus) PubMed

 18936.

This study showed that Beijing strains of M. tuberculosis all constitutively overexpress members of the DosR regulon, and that important phenotypic differences exist between distinct M. tuberculosis lineages, with the potential to impact the efficacy of diagnosis, vaccination, and treatment programs.[DosR] (Mus musculus) PubMed

 18937.

MoPdeH functions upstream of the MoMck1-MoMkk1-MoMps1 MAP kinase pathway to regulate cell wall integrity.[MoPdeH, MoMck1] (Mus musculus) PubMed

 18938.

the resistance conferred by cmv1 was characterized and established that CMV-LS (subgroup II) can move from cell to cell up to the veins in the inoculated leaf, but cannot enter the phloem. [Cmv1] (Mus musculus) PubMed

 18939.

miR-203a directly regulated dmrt2a expression to control fast and slow muscle development (Mus musculus) PubMed

 18940.

Heme Proximal Hydrogen Bonding between His170 and Asp132 Plays an Essential Role in the Heme Degradation Reaction of HutZ from Vibrio cholera [HutZ] (Mus musculus) PubMed

 18941.

NMR structure of binding studies of PqqD [PqqD] (Mus musculus) PubMed

 18942.

Nucleic acid-dependent conformational changes in CRISPR-Cas9 revealed by site-directed spin labeling have been described. [Cas9] (Mus musculus) PubMed

 18943.

Moreover, apPOL (apicoplast DNA polymerase) has an additional N-terminal subdomain, the absence of which severely diminishes its 3' to 5' exonuclease activity.[apPOL] (Mus musculus) PubMed

 18944.

Mutating residues located on an extended loop at the edge of the PafA active site rendered PafA defective in the pupylation of a wide variety of protein targets but not in its catalytic mechanism, suggesting an important role for this extended loop in the binding of protein targets.[PafA] (Mus musculus) PubMed

 18945.

C1qr and c1qrl regulate angiogenesis through controlling endothelial cdh5 expression.c1qr and c1qrl redundantly regulate angiogenesis in zebrafish. [c1qrl] [c1qr] (Mus musculus) PubMed

 18946.

Further analysis indicated that fitness-virulence impairment is caused by overexpressing ampC in the absence of cell wall recycling, as reproduced by expressing ampC from a plasmid in an AmpG (muropeptide permease)-deficient background.[ampC] (Mus musculus) PubMed

 18947.

The functions of the locus of enterocyte effacement encoded protein EscK in the type III secretion system and its relationship to other E. coli proteins are reported.[EscK] (Mus musculus) PubMed

 18948.

This study identified an FtsZ loop where various fluorescent proteins could be inserted without blocking function; these FtsZ-FPs functioned as the sole source of FtsZ.[FtsZ] (Mus musculus) PubMed

 18949.

These results suggest that SecA could recognize substrate proteins cotranslationally in order to efficiently target them for uncoupled protein translocation.[SecA] (Mus musculus) PubMed

 18950.

The authors demonstrate that the strength of Cna-collagen bonds in vivo is very strong (~1.2 nN), consistent with the high-affinity "collagen hug" mechanism.[Cna] (Mus musculus) PubMed

 18951.

The authors show here that the staphylococcal phenol-soluble modulin (PSM) toxins have gene regulatory functions that, in particular, include inducing expression of their own transport system by direct interference with a GntR-type repressor protein.[PSM] (Mus musculus) PubMed

 18952.

Overexpression of epoxide hydrolases PfEH1 or PfEH2 in parasite-infected erythrocytes resulted in a significant alteration in the epoxide fatty acids stored in erythrocyte phospholipids.[PfEH1, PfEH2] (Mus musculus) PubMed

 18953.

Additional interaction studies showed that, although mycosins MycP1 and MycP5 are not part of the ESX type VII secretion system central membrane complex, they loosely associate with this complex and this MycP association with the core membrane complex is crucial for the integrity and functioning of the secretion system machinery. (Mus musculus) PubMed

 18954.

Functional analysis of plantaricin E and its mutant by heterologous expression in Escherichia coli has been reported. [plantaricin E] (Mus musculus) PubMed

 18955.

Tsn1 and Tsc1 were associated with tan spot susceptibility [Tsn1; Tsc1] (Mus musculus) PubMed

 18956.

The water-filled channel of MOMP has a narrow constriction zone, and single-molecule studies show a monomeric conductivity of 0.7+/-0.2 nS and a trimeric conductance of 2.2+/-0.2 nS.[MOMP] (Mus musculus) PubMed

 18957.

Results identify GEI-12, a novel binding partner of the DYRK family kinase MBK-2, as a key regulator of P granule formation and germline maintenance. [GEI-12] (Mus musculus) PubMed

 18958.

AphA binds directly to the aphA promoter and negatively regulates its own expression. [AphA] (Mus musculus) PubMed

 18959.

This study uncovers an anti-sense lncRNA (APOA4-AS), which is co-expressed with APOA4, and concordantly and specifically regulates APOA4 expression both in vitro and in vivo with the involvement of HuR. (Mus musculus) PubMed

 18960.

Both CRH-1 and FLP-6 are necessary and sufficient for longevity at warm temperatures.[FLP-6] (Mus musculus) PubMed

 18961.

Overexpression of SOCS2 inverted these phenotypes generated by hsv2-miR-H9-5p, indicating the potential roles of SOCS2 in Hsv2-miR-H9-5p-driven metastasis in lung cancers. The results highlighted that Hsv2-miR-H9-5p regulated and contributed to bone metastasis of lung cancers. We proposed that Hsv2-miR-H9-5p could be used as a potential target in lung cancer therapy (Mus musculus) PubMed

 18962.

alanine-scanning mutagenesis of the Ourmia melon virus (OuMV) MP was performed, and studied the effects of amino acid substitutions on MP properties and virus infection.[MP] (Mus musculus) PubMed

 18963.

RNA sequencing was used to identify the full target repertoire of TAL14Xam668 in cassava.[TAL14Xam668] (Mus musculus) PubMed

 18964.

ART1 plays an important role in both trichothecene and fumonisin biosynthesis by the regulation of genes involved in starch hydrolysis. [ART1] (Mus musculus) PubMed

 18965.

MoSKP1 plays important roles in growth, sporulation, appressorial development and pathogenicity of M. oryzae.[MoSkp1] (Mus musculus) PubMed

 18966.

C. graminicola Str1 shares five phenotypes with striatin orthologues in other fungal species: hyphal growth, hyphal fusion, conidiation, sexual development and virulence.[Str1] (Mus musculus) PubMed

 18967.

ART1 plays an important role in both trichothecene and fumonisin biosynthesis by the regulation of genes involved in starch hydrolysis.[ART1] (Mus musculus) PubMed

 18968.

Four QTL related to haploid male fertility were detected by a segregation distortion method and the key QTL qhmf4 was fine mapped to an interval of ~800 kb. [qhmf4] (Mus musculus) PubMed

 18969.

The full-length complementary DNA of BmiTrxR was 1766 bp and contained an intact open reading frame with 1662 bp that encoded a polypeptide with 553 amino acids. [TrxR] (Mus musculus) PubMed

 18970.

Data suggest that, in active site of katG, a discrete group of protonable residues are contained within a 15 A sphere surrounding the heme iron; a computational analysis reveals that pKa of distal His112, alone, is modulated within pH range of catalase activity by remote acidic residues in pattern consistent with its protonated form having key role in catalase reaction cycle. [katG, catalase-peroxidase] (Mus musculus) PubMed

 18971.

Results demonstrate that NHBA contributes to meningococcal adhesion to epithelial cells through binding to heparan sulfate proteoglycans. [NHBA] (Mus musculus) PubMed

 18972.

The authors demonstrate that the C terminus of gamma directly participates in membrane penetration.[gamma] (Mus musculus) PubMed

 18973.

TaCPK7-D positively regulates the wheat resistance response to R. cerealis infection.[TaCPK7-D] (Mus musculus) PubMed

 18974.

Both Acs1 purified from Syntrophus aciditrophicus and recombinantly produced Acs1 catalyzed ATP and acetate formation from acetyl-CoA, AMP, and pyrophosphate.[Acs1] (Mus musculus) PubMed

 18975.

The role of TDP2-ubiquitin interactions in the repair of topoisomerase II-mediated DNA damage [tdp2] (Mus musculus) PubMed

 18976.

the essential role of the Mediator complex in the transcriptional activation of ACR2 by Yap8, is reported.[ARC2, Yap8] (Mus musculus) PubMed

 18977.

LigB bound to factor XIII and further interfered with the cross-linking of fibrinogen [LigB] (Mus musculus) PubMed

 18978.

we found that mexZ mutations contribute substantially to amikacin resistance through increased mexY mRNA expression. [mexZ] (Mus musculus) PubMed

 18979.

XacFhaB shows features resembling pathogen-associated molecular patterns (PAMPs), which are recognized by plants.[XacFhaB] (Mus musculus) PubMed

 18980.

Our docking model of TkoTrm11-SAM in complex with tRNA, combined with biochemical analyses and pre-existing evidence, provides insights into the substrate tRNA recognition mechanism: The THUMP domain recognizes a 3'-ACCA end, and the linker region and RFM domain recognize the T-stem, acceptor stem and V-loop of tRNA, thereby causing TkoTrm11 to specifically identify its methylation site. (Mus musculus) PubMed

 18981.

Collectively, these results suggest that Staphylococcus aureus senses metabolic shifts by RpiRc to differentially regulate the expression of leukocidins and to promote invasive disease.[RpiRc] (Mus musculus) PubMed

 18982.

Sre1 and Mga2 are each regulated by the lipid product of the other transcription factor pathway, providing a source of coordination for these two branches of lipid synthesis.[Mga2] (Mus musculus) PubMed

 18983.

Alterations in the distribution of yeast EB1 explain chromosome segregation defects upon knockout, overexpression or stabilization of Kar9 and provide an example for non-linear effects on microtubule-associated proteins behavior after perturbation of their equilibrium.[Kar9, EB1] (Mus musculus) PubMed

 18984.

NUP-1 is mislocalized in NUP-2 knockdown cells and vice versa, implying that NUP-1 and NUP-2 form a co-dependent network and identifying NUP-2 as a second trypanosomatid nuclear lamina component. [NUP-2] (Mus musculus) PubMed

 18985.

These results identify PB1-F2 as an important immune disruptive factor during the influenza A virus infection.pOB1-F2] (Mus musculus) PubMed

 18986.

This structural study clarifies the extent of unfolding that AAC(6')-Ii undergoes in the absence of acetyl coenzyme A (AAC(6')-Ii). (Mus musculus) PubMed

 18987.

The role of the loop 1 region in MazFbs mRNA interferase from Bacillus subtilis in recognition of the 3' end of the RNA substrate. [MazFbs] (Mus musculus) PubMed

 18988.

Point mutations at the six Cys residues of the CRD have revealed the contribution of each residue to CorE2 activity. However, importantly, mutation of Cys174 completely shifts the specificity of CorE2 from cadmium to copper, indicating that the Cys arrangement of the CRD determines the metal specificity (Mus musculus) PubMed

 18989.

the infection phenotype of the Deltabcsod1 strain in both tomato and Arabidopsis plants, is reported.[BcSOD1] (Mus musculus) PubMed

 18990.

MoSec62, probably as an endoplasmic reticulum membrane transporter, plays an essential role in antagonizing rice defence at the early stages of blast invasion.[MoSec62] (Mus musculus) PubMed

 18991.

Oligogalacturonides are sensed through multiple and partially redundant perception/transduction complexes, some targeted by AvrPto, but not necessarily comprising BAK1 and BKK1.[AvrPto] (Mus musculus) PubMed

 18992.

an X-ray crystal structure of the wild-type, ribosome-dependent toxin HigB bound to the ribosome revealing potential catalytic residues proximal to the mRNA substrate, is reported.[HigB] (Mus musculus) PubMed

 18993.

Tal2a as an hypersensitive reaction elicitor in rice.[Tal2a] (Mus musculus) PubMed

 18994.

GflB is an essential upstream regulator of chemoattractant-mediated cell polarity and cytoskeletal reorganization functioning to directly link Galpha activation to monomeric G-protein signaling.[GflB] (Mus musculus) PubMed

 18995.

first report of a coordinated global transcriptomic response that is triggered by an increase in DNA supercoiling in bacteria, mediated by the DNA topoisomerase I gene [topI] (Mus musculus) PubMed

 18996.

SMUG2 DNA glycosylase from Pedobacter heparinus as a new subfamily of the UDG superfamily has been characterized.[SMUG2] (Mus musculus) PubMed

 18997.

The data suggest an assembly code that defines preferred oligomerization modes of the B-repeat region of Aap and a slip-grip model for initial contact followed by firm intercellular adhesion during biofilm formation. [Aap] (Mus musculus) PubMed

 18998.

The findings point towards a salient role for Trp288 in the kinetics of copper loading and maturation of GlxA, with its presence essential for stabilizing the metalloradical site required for coupling catalytic activity and morphological development. [GlxA] (Mus musculus) PubMed

 18999.

data demonstrate that both PLC1 and PLC2, which have diverged from a common ancestor, play a concerted role in hemolytic and cytolytic activities; although PLC1 seems to play a more critical role in the virulence of A. baumannii when tested in an invertebrate model. (Mus musculus) PubMed

 19000.

report of a novel null Wx-B1 allele that was caused by a transposon insertion [Wx-B1] (Mus musculus) PubMed

 19001.

Here the authors report that EspG interacts specifically with the small GTPases ARF6 and Rab35 during infection.[EspG] (Mus musculus) PubMed

 19002.

Copper(I) stabilization by cysteine/tryptophan motif in the extracellular domain of Ctr4. (Mus musculus) PubMed

 19003.

HrpF interacts directly with HrpG and HrpA in vitro and in vivo.[HrpA, HrpF, HrpG] (Mus musculus) PubMed

 19004.

TbERK8 phosphorylates TbPCNA.[TbERK8, TbPCNA] (Mus musculus) PubMed

 19005.

Using transient expression assays, within BHK-21 cells, it was found that residues around the active site (W52, L53 and A149) of Lpro and others located elsewhere (K38, K39, R44, H138 and W159) are involved in the induction of eIF4G cleavage but not in the processing of the L/P1 junction.[Lpro] (Mus musculus) PubMed

 19006.

The authors propose that TagX, a peptidoglycan hydrolase possessing l,d-endopeptidase activity, is the first identified enzyme that fulfills the important role of enabling the transit of type VI secretion system machinery across the peptidoglycan layer of the type VI secretion system-producing bacterium.[TagX] (Mus musculus) PubMed

 19007.

Replication kinetics of bovine adenovirus 3 mutants with either one or two stop codons in the 155R open reading frame were comparable to those of wild-type bovine adenovirus 3, indicating that 155R is not essential for virus replication in cell culture.[155R] (Mus musculus) PubMed

 19008.

In this study the role of His 72 in TmPurL, a glutamine amidotransferase (GAT) enzyme, is investigated. TmPurL is a large 66kDa enzyme that works as part of an even larger (>100kDa) multi-protein complex. Ammonia channeling and allostery are discussed for GATs and more specifically for PurL family. [glutamine amidotransferase] (Mus musculus) PubMed

 19009.

YopJ mediates Ser- and Lys-acetylation and affects auto-ubiquitination of ubiquitin ligase MARCH8 in human cells.[YopJ] (Mus musculus) PubMed

 19010.

Transmission electron microscopy analysis of the LH92_11085 mutant showed the absence of long pili formations normally present in the wild-type. These observations indicate the potential role this LH92_11085 gene could play in the pathobiology of A baumannii [LH92_11085]. (Mus musculus) PubMed

 19011.

Using the v-rel-induced transformation model on chicken embryonic splenocyte cultures, the authors could demonstrate a dynamic increase in miR-155 levels during the transformation.[v-rel] (Mus musculus) PubMed

 19012.

Importantly, AI-2 signaling via FruA enables the bacterium to utilize galactose as a carbon source and upregulates the Leloir pathway, thereby leading to increased production of capsular polysaccharide and a hypervirulent phenotype.[FruA] (Mus musculus) PubMed

 19013.

These data suggest that mutations in the periplasmic sensing loop of QseC differentially affect the expression of the three arms of this signaling cascade. This suggests that these point mutations may change QseC's phosphotransfer preferences for its response regulators.[QseC] (Mus musculus) PubMed

 19014.

These results clarify Mediator recruitment and binding to the genome, showing that Mediator binding to UASs is widespread, partially uncoupled from transcription, and mediated in part by TFIID.[TFIID] (Mus musculus) PubMed

 19015.

These data support the assertion that FRH helicase activity does not play an essential role in the clock, but rather FRH acts to mediate contacts among FRQ, CK1a and the WCC through interactions involving its N-terminus and KOW module.[FRH] (Mus musculus) PubMed

 19016.

L-GalLDH-suppressed transgenic rice, GI-1 and GI-2, which have constitutively low (between 30% and 50%) leaf and grain Ascorbic acid content compared with the wild-type (WT), exhibit significantly increased grain chalkiness.[L-GalLDH] (Mus musculus) PubMed

 19017.

Taken together, these results indicate that the anti-melanization activity of white spot syndrome virus is due to WSSV453, which interacts with Penaeus monodon proPPAE2 and interferes with its activation to active PPAE2.[WSSV453] (Mus musculus) PubMed

 19018.

Results show the cytochrome P450 monooxygenase CYP109E1 (CYP109E1) activity, substrate specificity, and regio/stereoselectivity: [CYP109E1] (Mus musculus) PubMed

 19019.

Specific interaction of Vipp1 with cyanobacterial and chloroplast membranes results in membrane remodeling and eventually in membrane fusion. (Review) [Vipp1] (Mus musculus) PubMed

 19020.

crystal structure of RraAS2, exhibiting a hexamer arranged in a dimer of trimmers; findings present the first bacterial RraA that has a hexameric assembly with a C-terminal extension alpha-helical region, which plays an essential role in the regulation of RNase ES activity [RraAS2] (Mus musculus) PubMed

 19021.

Glutathione S-transferase theta was identified as a candidate gene associated with Hailey-Hailey disease using Kluyveromyces lactis model. (Mus musculus) PubMed

 19022.

study concludes that the C. burnetii effector protein CaeA interferes with the intrinsic and extrinsic apoptosis pathway. The process requires the EK repetition motif of CaeA, but is independent of the upregulated expression of surviving [CaeA]. (Mus musculus) PubMed

 19023.

These results suggest that PilB2 activity is controlled by c-di-GMP levels in vivo.[PilB2] (Mus musculus) PubMed

 19024.

This study is the first report that links OmpA to A. nosocomialis pathogenesis, and highlights OmpA as a putative target to develop anti-virulence agents or vaccines against A. nosocomialis infection [OmpA]. (Mus musculus) PubMed

 19025.

inhibiting the KCa3.1 ion channel is able to attenuate the early fibrogenic phase of bleomycin-dependent fibrosis.[Kca3.1] (Mus musculus) PubMed

 19026.

Fpk1 phosphorylates and inhibits protein kinase Akl1, related to protein kinases Ark1 and Prk1, which modulate the dynamics of actin patch-mediated endocytosis.[Fpk1, Ark1, Prk1, Akl1] (Mus musculus) PubMed

 19027.

HBS (Hsk1 bypass segment) on Mrc1, was identified.[Mrc1, Ksk1] (Mus musculus) PubMed

 19028.

NgBR expression in pulmonary hypertension of the newborn contributes to increased pulmonary artery smooth muscle cell proliferation and oxidative stress, which lead to the pathogenesis of lung injury.[NgBR] (Mus musculus) PubMed

 19029.

These results support that CYP52G3 could prove a useful enzyme for the efficient production of new compounds from flavonoids and steroids. (Mus musculus) PubMed

 19030.

HIF-1alpha-c-Myc-TFAM signaling pathway participates in the regulation of mitochondrial activity for insect diapause or lifespan extension. (Mus musculus) PubMed

 19031.

data show that PRRSV nsp11 endoribonuclease activity is critical for both viral replication and IFN antagonism. (Mus musculus) PubMed

 19032.

This study showed that the sensitivity of a gene to RpoS levels explains the timing of expression as cells enter stationary phase and that genes with different RpoS sensitivities are enriched for specific functional groups.[RpoS] (Mus musculus) PubMed

 19033.

The observed interaction between DdN-NKAP and the DdDUF926 domain indicates that the DdDUF926 domain acts as negative regulator of the N-terminus. (Mus musculus) PubMed

 19034.

the presence of GSNO reductase activity in V. cholerae and that it plays an important role to detoxify S-Nitrosoglutathione. GSNO reductase activity of V. cholerae was regulated by posttranslational modification through S-nitrosylation under in vitro conditions which could be reversed by dithiothreitol (DTT) (Mus musculus) PubMed

 19035.

T2 homozygous OsSNAT1 transgenic rice plants exhibited increased grain yield due to increased panicle number per plant under paddy field conditions. These benefits conferred by ectopic overexpression of OsSNAT1 had not been observed in transgenic rice plants overexpressing ovine SNAT, suggesting that plant SNAT functions differently from animal SNAT in plants. (Mus musculus) PubMed

 19036.

Using a simulation-guided approach this study determined precise local proton association and dissociation rates and provided information about cytochrome c oxidase surface effects, such as proton collecting antennae, on the transport properties of proton transfer channels. [cytochrome c oxidase] (Mus musculus) PubMed

 19037.

LapF is the hydrophobicity factor for the cell surface of P. putida [LapF][Fis] (Mus musculus) PubMed

 19038.

The authors report here that in Neisseria gonorrhoeae, expression of gdhR is subject to autoregulation by GdhR and direct repression by MtrR.[GdhR, MtrR] (Mus musculus) PubMed

 19039.

the expressions of the VlMYBA1-2 and VlMYBA 2 genes, and the responses of the VlMYBA1-2/2 promoters to abscissic acid and 1-aminocyclopropane-1-carboxylic acid treatments in Kyoho grape berries are examined.[VYMBYA1-2, VIMBYA 2] (Mus musculus) PubMed

 19040.

Human herpesvirus 1 ICP27 interacted with TBK1 and STING in a manner that was dependent on TBK1 activity and the RGG motif in ICP27 and inhibited type I IFN induction through the cGAS-STING-TBK1 pathway in human macrophages.[ICP27] (Mus musculus) PubMed

 19041.

OXR1 participates in protecting larval silkworms from oxidative stress and bacterial infection through the Jun kinase pathway. [OXR1] (Mus musculus) PubMed

 19042.

binding site at the cleft between the PDZ1 and PDZ2 domains of GRASP65 is dominated by hydrophobic interactions with GM130 that are not observed in the GRASP55-Golgin45 complex [golgin45] (Mus musculus) PubMed

 19043.

The authors found that EscP, which was previously shown to function as the ruler protein of the enteropathogenic Escherichia coli T3SS, is also involved in the switch from the secretion of translocator proteins to the secretion of effector proteins. In addition, we demonstrated that EscP can interact with the gatekeeper protein SepL and that the EscP-SepL complex dissociates upon a calcium concentration drop.[EscP, SepL] (Mus musculus) PubMed

 19044.

Surprisingly, in this study biochemical analysis demonstrated that the Bacteroides thetaiotaomicron fumarate reductase (Frd) does not react with oxygen at all: neither superoxide nor hydrogen peroxide is formed.[Frd] (Mus musculus) PubMed

 19045.

The authors identified a minimal construct of the Aquifex aeolicus sigma(54) activator interacting domain that consists of two predicted helices and retains native-like binding affinity for the transcriptional activator NtrC1.[sigma(54) transcription factor] (Mus musculus) PubMed

 19046.

The authors show that a polymeric cell polarity protein, SpmX, serves as a direct bridge between the PopZ polymeric network and the cell fate-directing DivJ histidine kinase.[SpmX] (Mus musculus) PubMed

 19047.

The authors determined that the binding of TgDJ-1 to CDPK1 is sensitive to oxidation and calcium, and that this interaction potentiates CDPK1 kinase activity. Finally, we show that genetic deletion of TgDJ-1 results in upregulation of CDPK1 expression and that disruption of the CDPK1/TgDJ-1 complex in vivo prevents normal exocytosis of parasite virulence-associated organelles called micronemes.[DJ-1, CDPK1] (Mus musculus) PubMed

 19048.

The full-length cDNA of LycCD4-1 is 1695 bp long, encoding a protein of 462 amino acids. The deduced LycCD4-1 protein has a typical domain architecture as found in mammalian CD4 molecules (CD4-1). (Mus musculus) PubMed

 19049.

Based on the results presented here, the authors propose that GigA and GigB are master regulators of a global stress response in Acinetobacter baumannii, and coupling this pathway with the PTS(Ntr) allows Acinetobacter baumannii to integrate cellular metabolic status with external environmental cues.[GigA, GigB] (Mus musculus) PubMed

 19050.

Wild type A. salmonicida exhibited autoinducer-2 (AI-2) activity and luxS defective mutant strain fail to produce AI-2 signals. Furthermore, it was suggested that luxS deficiency could impact bacterial morphology, surface properties and virulence dramatically. [luxS] (Mus musculus) PubMed

 19051.

Greater mortality occurred at all doses tested when control virus was injected in the footpads of BALB/c mice compared to the C15 mutant. (Mus musculus) PubMed

 19052.

[TPB1] and [TPB6] TPB1 and TPB6 excise a small, distinct set of 12 unusual internal eliminated sequences that disrupt exons. (Mus musculus) PubMed

 19053.

the crystal structure of the anti-CRISPR protein AcrF3 in complex with Pseudomonas aeruginosa Cas3. (PaCas3) (Mus musculus) PubMed

 19054.

D-alanyl-D-alanine carboxypeptidase and HlyD protein, were identified as FTS_1067 interacting proteins. [ DsbA, FTS_1067 ] (Mus musculus) PubMed

 19055.

PBP1B plays an essential role in synthesizing peptidoglycan in the absence of a preexisting template: its glycosyltransferase activity is responsible for de novo synthesis, while its transpeptidase activity is required to construct cell walls of a specific shape. [PBP1B] (Mus musculus) PubMed

 19056.

This study investigated M. tuberculosis proteasome accessory factor E (PafE) mutants that exhibited slowed growth an sensitivity to heat; the role of HspR degradation, or other defect in the protein quality control pathway was evaluated.[PafE; HspR] (Mus musculus) PubMed

 19057.

This demonstrates that murine cytomegalovirus M48 deubiquitinase activity plays a previously unappreciated role in controlling the viral C-C chemokine MCK2 levels, thereby managing MCK2-dependent processes.[M48, MCK2] (Mus musculus) PubMed

 19058.

this study shows that mesenchymal stem cells over-expressing IL-35 have higher immunosuppressive capacity compared with non-transfected MSCs, and may provide a useful approach for basic research on gene therapy for autoimmune disorders (Mus musculus) PubMed

 19059.

MalL is an oligo-alpha-1,6-glucosidase from Lactobacillus plantarum [MalL] (Mus musculus) PubMed

 19060.

Tim17 transmembrane regions is critical for mitochondrial function and protein turnover.[Tim17] (Mus musculus) PubMed

 19061.

Interacts with receptor for Activated C-Kinase 1(OsRACK1) to regulate blast resistance through salicylic acid and ethylene signaling pathways - [COL9] (Mus musculus) PubMed

 19062.

RibJ is a novel riboflavin transporter family in trypanosomatids [RibJ] (Mus musculus) PubMed

 19063.

RibJ is a novel riboflavin transporter family in trypanosomatids [RibJ] (Mus musculus) PubMed

 19064.

In summary, the authors provide evidence that Trypanosoma brucei harbors TbIF1, a natural and potent unidirectional inhibitor of the vital FoF1-ATPase activity.[TbIF1] (Mus musculus) PubMed

 19065.

expression and sequence analysis results provide preliminary evidence that it is a candidate gene for the seed coat color trait - [TT1] (Mus musculus) PubMed

 19066.

Study of Deinococcus radiodurans Nramp structure reveals TM1a location in inward-open state which is essential to the metal transport cycle. Also, G153R disease-mutant mimic alters selectivity of conserved metal-binding site and G45R disease-mutant mimic sterically locks protein in inward-open state. [Nramp] (Mus musculus) PubMed

 19067.

After infection of bovine mammary epithelial cells (MAC-T), the double mutant (DeltavraGDeltahemB) was less internalized and caused less cell destruction than that seen with DeltahemB and DeltavraG, respectively.[vraG] (Mus musculus) PubMed

 19068.

Here, the authors show that TssA1 is a type VI secretion system component forming dodecameric ring structures whose dimensions match those of the TssBC sheath and which can accommodate the inner Hcp tube.[TssA1] (Mus musculus) PubMed

 19069.

The effect of relaxin knockout on the response of the mesenteric and uterine arteries to angiotensin II (ANG II) is reported.[ANGII] (Mus musculus) PubMed

 19070.

The role of KatG and AhpC in isoniazid resistance and virulence [KatG] [ AhpC ] (Mus musculus) PubMed

 19071.

miR-128-3p directly targets p38alpha 3'UTR and downregulates p38alpha protein level. (Mus musculus) PubMed

 19072.

Structure, Function, and Membrane Interactions of OmpA [OmpA] (Mus musculus) PubMed

 19073.

These data expose Asc1p/RACK1 as a key factor in phosphosignaling and manifest it as a control point at the head of the ribosomal 40S subunit itself regulated through posttranslational modification.[Asc1] (Mus musculus) PubMed

 19074.

The authors present here a topological view of the Actinomyces oris membrane-spanning protein vitamin K epoxide reductase (VKOR) with its four exoplasmic cysteine residues that participate in MdbA reoxidation.[VKOR, MdbA] (Mus musculus) PubMed

 19075.

UbaA was defined in terms of its nucleotide ligands, thermodynamics of ubiquitin-like protein binding, thioester intermediate, regulation by automodification, and amino acid residues important for catalytic function (UbaA). (Mus musculus) PubMed

 19076.

Lo18 improved cells tolerance to heat and acid conditions.[Lo18] (Mus musculus) PubMed

 19077.

Findings support a model in which TcDRBD4/PTB2-containing ribonucleoprotein complexes can prevent trans-splicing. This could represent another stage of gene expression regulation mediated by the masking of trans-splicing/polyadenylation signals [PTB2]. (Mus musculus) PubMed

 19078.

Embryonic liver fordin is involved in HSC glucose glycolysis by regulating PI3K/Akt signaling [ELF] (Mus musculus) PubMed

 19079.

interactions between OprH and LPS [OprH] (Mus musculus) PubMed

 19080.

Knockdown of OsOTS1 gene expression affects root growth by primarily reducing cell size rather than cell division.[OsOTS1] (Mus musculus) PubMed

 19081.

20 residues of TcpB which affect either the steady-state level of TcpB or alter one or more toxin-coregulated pilus functions.[TcpB] (Mus musculus) PubMed

 19082.

Mms6 localized along magnetosome chain structures under magnetite-forming conditions but was dispersed in the cell under aerobic conditions.[Mms6] (Mus musculus) PubMed

 19083.

Biochemical characterization of purified ANCUT2 cutinase from Aspergillus nidulans is described. (Mus musculus) PubMed

 19084.

Allosteric Signaling Is Bidirectional in an Outer-Membrane Transport Protein [BtuB] (Mus musculus) PubMed

 19085.

SirE appears to control this metabolic transition via a mechanism associated with the starvation response. (Mus musculus) PubMed

 19086.

Data suggest that deamidation of CsgA (major protein subunit of curli), which has a high content of asparagine and glutamine, slows fibrillization/aggregation; CsgA may serve as a model for studies of pathological amyloid aggregation. [CsgA, major curli subunit] (Mus musculus) PubMed

 19087.

Data suggest that NDPK exhibits nativelike dimers, each of its monomers having a major subdomain folded, while a minor subdomain remains unfolded; catalytic subdomain exhibits discreet structure only upon hexamerization, explaining why oligomerization is required for NDPK activity. [NDPK, nucleoside diphosphate kinase] (Mus musculus) PubMed

 19088.

Data suggest that, for cel7a, increased physical stability can occur as a direct result of O-glycosylation; the previously observed stabilizing effects of O-glycans come from introduction of new bonding interactions to structure and increased rigidity, while decreased stability seems to result from impaired interactions and increased flexibility. [cel7a, cellobiohydrolase, family 7 OR glycoside hydrolase family 7] (Mus musculus) PubMed

 19089.

Isolated hemolysin from periodontopathogenic bacterium Eikenella corrodens strain 1073 is identical to X-prolyl aminopeptidase. [X-prolyl aminopeptidase] (Mus musculus) PubMed

 19090.

Data suggest that Cox15 (cytochrome c oxidase-type aa3) acts as heme A synthase and is essential for survival, proliferation, and infectivity of Trypanosoma cruzi Dm28c; Cox15 serves as the main terminal oxidase in all of T. cruzi life-cycle stages; Cox15 activity is essential for growth and infectivity of this parasite. [Cox15, cytochrome c oxidase-type aa3] (Mus musculus) PubMed

 19091.

The results indicate that lipoteichoic acid has an essential role in septum placement that can be bypassed by inactivating the ClpX chaperone.[ClpX] (Mus musculus) PubMed

 19092.

Further studies reveal that Sulfolobus islandicus PilT N-terminal-domain-containing ATPase (SisPINA) interacts with the Holliday junction resolvase SisHjc and coordinates Holliday junction migration and cleavage.[SisPINA, SisHjc] (Mus musculus) PubMed

 19093.

2.3 A structure of dark-adapted D217E mutation Anabaena sensory rhodopsin, which reveals significant changes in the water network surrounding Glu217, as well as a shift in the carbon backbone near retinal-binding Lys210. [sensory rhodopsin] (Mus musculus) PubMed

 19094.

Results present the crystal structures of PRS17 in the inhibitor-free form and in complex with darunavir. They show the open-closed flap conformation of the inhibitor free PRS17 bearing an active site D25N mutation and reveal distinct mutational clusters in PRS17 and their molecular basis for high drug resistance. [PRS17] (Mus musculus) PubMed

 19095.

Results show the cloning of the complete cDNA sequence of a putative OA/TA receptor, CgGPR1. Phylogenetic analysis showed that CgGPR1 has no vertebrate homologs, indicating a unique invertebrate-specific evolution for these receptors. The expression pattern of CgGPR1 was found in all developmental stages. [GPr1] (Mus musculus) PubMed

 19096.

The authors provide evidence that Hippo kinases inhibit RhoG activity locally and are in turn restricted to the cell body by RhoG-mediated polarization. Therefore, they propose that the Hippo-RhoG feedback regulation maintains cell polarity during directional cell motility. (Mus musculus) PubMed

 19097.

Sld3 binds specifically to DDK-phosphorylated peptides from two MCM subunits (Mcm4, 6) and then recruits Cdc45. (Mus musculus) PubMed

 19098.

These results suggested that 2', 3'-cyclic phosphodiesterase (cpdB) is involved in the long-term colonization of avian pathogenic Escherichia coli in the internal organs of chickens.[cpdB] (Mus musculus) PubMed

 19099.

These data are compatible with a model in which the terminase small subunit TerS interactions with part of the pacL sequence and a poly-A tract in pacR are sufficient to orient very accurately the TerL large terminase subunit to a defined pacC position.[TerS, TerL] (Mus musculus) PubMed

 19100.

OmpA2-loop 4 plays an important role in the interaction with host cells. These data demonstrate for the first time the important role of P. gingivalis OmpA2 extracellular loops in interaction with epithelial cells, which may help design novel peptide-based antimicrobial therapies for periodontal disease. [OmpA2] (Mus musculus) PubMed

 19101.

BcATG1 plays a critical role in numerous developmental processes and is essential to the pathogenesis of B. cinerea.[BcATG1] (Mus musculus) PubMed

 19102.

Data suggest that FNO (F420:NADPH oxidoreductase) is thermostable, the first F420-dependent enzyme described from Thermobifida fusca; the active site is located in a hydrophobic pocket between an N-terminal dinucleotide binding domain and a smaller C-terminal domain. [FNO, F420:NADPH oxidoreductase] (Mus musculus) PubMed

 19103.

Effect of Porphyromonas gingivalis Methionine Gamma Lyase on Biofilm Composition and Oral Inflammatory Response [mgl] (Mus musculus) PubMed

 19104.

These findings indicate that OsWOX3A may be involved in modulation of gibberellic acid-auxin crosstalk in rice root development.[OsWOX3A] (Mus musculus) PubMed

 19105.

Data suggest that an R165A mutation disrupts the characteristic long interburst closed state of reconstituted KirBac1.1 in giant liposomes; the ligand PIP2 (phosphatidylinositol bisphosphate) essentially induces opposite motions of major beta-sheet in this channel mutant. [Kir1.1, potassium channel, inwardly rectifying] (Mus musculus) PubMed

 19106.

Data suggest that juvenile hormone stimulates juvenile hormone receptor (methoprene-tolerant, Met) and activates expression of genes encoding regulator of ribosome synthesis 1 (RRS1) and six ribosomal proteins (two ribosomal large subunit proteins, two ribosomal small subunit proteins, and two mitochondrial ribosomal proteins). [JH, juvenile hormone; Met, juvenile hormone receptor; RRS1, regulator of ribosome synthesis 1] (Mus musculus) PubMed

 19107.

Data suggest that, in DddK, Tyr64 is responsible for beta-elimination leading to production of acrylate and dimethyl sulfide; DddK displayed promiscuous binding to various metal ions but exhibited a preference for select divalent transition metal ions such as nickel(II) in catalyzing dimethylsulfoniopropionate cleavage reaction. [DddK, dimethylsulfoniopropionate lyase] (Mus musculus) PubMed

 19108.

Asp30 of Aspergillus oryzae cutinase CutL1 is involved in the ionic interaction with fungal hydrophobin RolA. [CutL1]; [RolA] (Mus musculus) PubMed

 19109.

study suggests novel mechanistic links among SPASM domain radical SAM enzymes and supports the involvement of non-cysteinyl ligands in the coordination of auxiliary clusters. (Mus musculus) PubMed

 19110.

Data suggest that human XPNPEP3 (X-prolyl aminopeptidase 3), Ashbya gossypii Icp55, and Fusarium graminearum Icp55 exhibit structural and functional properties of genuine Xaa-Pro specific aminopeptidases; these enzymes appear to function in the previously observed mitochondrial role of Icp55 in processing of Nfs1 (mitochondrial cysteine desulfurase) substrate. [Icp55, intermediate-cleavage metalloexopeptidases 55] (Mus musculus) PubMed

 19111.

Data suggest that human XPNPEP3 (X-prolyl aminopeptidase 3), Ashbya gossypii Icp55, and Fusarium graminearum Icp55 exhibit structural and functional properties of genuine Xaa-Pro specific aminopeptidases; these enzymes appear to function in the previously observed mitochondrial role of Icp55 in processing of Nfs1 (mitochondrial cysteine desulfurase) substrate. [Icp55, intermediate-cleavage metalloexopeptidases 55] (Mus musculus) PubMed

 19112.

results demonstrate that E. faecalis can efficiently use glycogen degradation products results show that one of two different transporters is used: the maltose-PTS transporter MalT, or the MdxEFG-MsmX ABC transporter [the maltose-PTS transporter MalT]. (Mus musculus) PubMed

 19113.

CAMP factor 1 may contribute to P. acnes virulence, by amplifying the inflammation reaction through direct interaction with TLR2 [CAMP factor 1] (Mus musculus) PubMed

 19114.

study employed a genetic screen to identify genes essential for hormogonium development and motility in Nostoc punctiforme The first gene identified using this screen encodes a eukaryotic-like O-linked beta-N-acetylglucosamine transferase that is required for accumulation of PilA in hormogonia [beta-N-acetylglucosamine transferase;OGT ]. (Mus musculus) PubMed

 19115.

MKP-5-mediated regulation of JNK negatively regulates phosphorylation of GRAB, which subsequently controls secretion of IL-6 [GRAB= guanine nucleotide exchange factor for Rab3A] (Mus musculus) PubMed

 19116.

nucleoid exclusion also contributes to the preference of Tsr clusters for polar localization [tsr] (Mus musculus) PubMed

 19117.

a molecular understanding of ion entry in Cu(+)-transporting P-type ATPases [CopA] (Mus musculus) PubMed

 19118.

we determined the crystal structure of Schizosaccharomyces pombe eIF2B. In this Structural Snapshot, we present the structural features of eIF2B and the mechanism underlying the GEF activity inhibition by the phosphorylation of eIF2alpha, elucidated from structure-based in vitro analyses. (Mus musculus) PubMed

 19119.

OxsB represents the first biochemically characterized non-methylating Cbl-dependent AdoMet radical enzyme [OxsB] (Mus musculus) PubMed

 19120.

Arginase of Helicobacter Gastric Pathogens Uses a Unique Set of Non-catalytic Residues for Catalysis [arginase] (Mus musculus) PubMed

 19121.

The authors studied the downstream effects and found that Ehrlichia chaffeensis TRP120-mediated activation of the Notch pathway causes inhibition of the extracellular signal-regulated kinase 1/2 (ERK1/2) and p38 mitogen-activated protein kinase (MAPK) pathways required for PU.1 and subsequent Toll-like receptor 2/4 (TLR2/4) expression.[TRP120] (Mus musculus) PubMed

 19122.

TLR5 but not NLRC4 is required for S. pneumoniae FliC-induced protection. [FliC] (Mus musculus) PubMed

 19123.

Heading date quantitative trait loci in winter wheat (Triticum aestivum L.) coincide with major developmental genes VRN1 and PPD1. [PPD1] (Mus musculus) PubMed

 19124.

Data suggest that covalent modifications (translational or post-translational) alter affinity of ArCP (aryl carrier protein) of the yersiniabactin synthetase protein HMWP2 toward its partner adenylation domain, YbtE. [YbtE, yersiniabactin siderophore biosynthetic protein; ArCP, aryl carrier protein; HMWP2, yersiniabactin synthetase, nonribosomal peptide synthetase, yersiniabactin biosynthetic protein (irp)] (Mus musculus) PubMed

 19125.

lip2 mutants were sensitive to oxidative stress provoked by hydrogen peroxide and by increased production of reactive oxygen species caused by inhibitors of mitochondrial functions.[Lip2] (Mus musculus) PubMed

 19126.

Inhibition of BDNF-AS protected retinal ganglion cells against ischemia by increasing the levels of BDNF. [BDNF-AS] (Mus musculus) PubMed

 19127.

these results show that ahpA is specifically expressed during biofilm formation, and not during sporulation or stationary phase, suggesting that derepression of ahpA by AbrB requires a signal other than those present upon entry into stationary phase. Despite this expression pattern, ahpA mutant strains still form and maintain robust biofilms. [AhpA] (Mus musculus) PubMed

 19128.

This work reveals the range of glycoprotein G structural changes and suggests that G monomers can re-associate, through antiparallel interactions between fusion domains, into dimers that play a role at some early stage of the fusion process.[G] (Mus musculus) PubMed

 19129.

This article reports the expression, purification, enzyme assay, and X-ray crystal structures of an AcAldDH from Geobacillus thermoglucosidasius (GtAcAldDH) to 2.1A and in complex with CoA and NAD(+) to 4.0A. (Mus musculus) PubMed

 19130.

Wpl1 triggered Rad21 de-phosphorylation in a Protein Phosphatase 4 (PP4)-dependent manner.[Wpl1, Rad21, PP4] (Mus musculus) PubMed

 19131.

Rdh2R acts as repressor by binding as tetramer to the direct-repeat motif of the rdhA (cbdbA1455) promoter. [Rdh2R, rdhA] (Mus musculus) PubMed

 19132.

C. rodentium NleB, EHEC NleB1, and SseK1 glycosylated host GAPDH. C. rodentium NleB, EHEC NleB1, EPEC NleB1, and SseK2 glycosylated the FADD (Fas-associated death domain protein). (Mus musculus) PubMed

 19133.

MXAN_1078 (named pxrR here) was found to positively regulate pxr transcription, presumably via the sigma(54) promoter of pxr.[pxrR] (Mus musculus) PubMed

 19134.

These data further confirm that miR-M11-5p, the miR-M11-derived mature miRNA, targets the viral oncogene meq and suppresses its expression in GaHV2 infection.[miR-M11] (Mus musculus) PubMed

 19135.

physical segregation of the Pex3- and PMP-binding domains of Pex19 has provided novel insights into the modular architecture of Pex19. (Mus musculus) PubMed

 19136.

TriB-dependent stimulation of the TriC transporter is coupled to opening of the OpmH aperture through binding to the H4-H7 interprotomer groove of OpmH. [OpmH, TriC. TriB] (Mus musculus) PubMed

 19137.

translocation substrates can be recruited to the Sec71-Sec72 complex either post-translationally through Ssa1 or co-translationally through Ssb1 [Sec71, Sec72, Ssb1] (Mus musculus) PubMed

 19138.

Results show that GltB regulates biofilm formation by altering the production of gamma-polyglutamate, the lipopeptides antibiotics bacillomycin L and fengcin and influences bacterial colonization on the rice stem, which consequently leads to poor biocontrol efficiency against rice sheath blight. [GltB] (Mus musculus) PubMed

 19139.

These results place Hfq and its newly identified sRNA anti-hfq in the center of the regulatory network governing Legionella pneumophila differentiation from nonvirulent to virulent bacteria.[Hfq] (Mus musculus) PubMed

 19140.

Fine mapping restricted a major maize QTL (quantitative trait locus) responsible for the aptitude of inducer lines to trigger gynogenesis to a zone containing a single gene NOT LIKE DAD (NLD) coding for a patatin-like phospholipase A. In all surveyed inducer lines, NLD carries a 4-bp insertion leading to a predicted truncated protein.[NLD] (Mus musculus) PubMed

 19141.

Results show that PilB in complex with ATP gamma-S assumes three distinct positions within the hexamer and the ring positions indicate a symmetric rotary catalytic mechanism of force generation. [PilB] (Mus musculus) PubMed

 19142.

Compared to the pre-splitting state, we observe repositioning of ABCE1's iron-sulfur cluster domain, which rotates 150 degrees into a binding pocket on the 40S subunit. This repositioning explains a newly observed anti-association activity of ABCE1.[ABCE1] (Mus musculus) PubMed

 19143.

CP40 is an endoglycosidase rather than a protease. [CP40] (Mus musculus) PubMed

 19144.

To investigate the underlying molecular mechanism of TbPSSA-2, we determined the crystal structures of its ectodomain and that of its homolog T. congolense Insect Stage Antigen (TcISA) to resolutions of 1.65 A and 2.45 A, respectively using single wavelength anomalous dispersion. Both proteins adopt a novel bilobed architecture with the individual lobes displaying rotational flexibility around the central tether (Mus musculus) PubMed

 19145.

the structure of the MamK filament at approximately 6.5 A, obtained by cryo-Electron Microscopy. This structure confirms our previously reported double-stranded, nonstaggered architecture, and reveals the molecular basis for filament formation. (Mus musculus) PubMed

 19146.

Our results suggest that NCA-1 and NCA-2 are physiologically relevant targets of neuronal Gq-Rho signaling in C. elegans (Mus musculus) PubMed

 19147.

AerR forms a 1:2 complex with CrtJ (AerR-CrtJ2) and this complex binds to many promoters under photosynthetic conditions.[AerR, CtrJ] (Mus musculus) PubMed

 19148.

The mcr-1 gene and NDM-1 were detected in Escherichia coli isolates from Venezuela. [mcr-1] [ndm-1] (Mus musculus) PubMed

 19149.

The first isolation of a K. pneumoniae strain producing blaGES-5 in China.[blaGES-5] (Mus musculus) PubMed

 19150.

Through co-expression analysis and DNA binding assays, the transcription factor bZIP14 was identified as a regulator of the tricarboxylic acid cycle, also beyond the nitrogen starvation response, namely in diurnal regulation. (Mus musculus) PubMed

 19151.

Porcine reproductive and respiratory syndrome virus induces apoptosis in host cells by the nonstructural proteins 4 and 10. [NP4]; [NP10] (Mus musculus) PubMed

 19152.

T. brucei senses heme levels via the flagellar TbHrg protein [TbHrg] (Mus musculus) PubMed

 19153.

Type II sites in the C-terminal portion was required for the function of SiiE in mediating adhesion and invasion.[SiiE] (Mus musculus) PubMed

 19154.

IncX4 plasmid carries the mcr-1 gene in a colistin-resistant Escherichia coli sequence type 101 isolate from a human infection in Brazil. [mcr-1] (Mus musculus) PubMed

 19155.

Collectively, these results suggest that MarP activates RipA to mediate peptidoglycan hydrolysis at low pH. (Mus musculus) PubMed

 19156.

The role of IleS2 gene in multidrug resistance [ileS2] (Mus musculus) PubMed

 19157.

IMP-27 was identified in Proteus mirabilis isolates [IMP-27] (Mus musculus) PubMed

 19158.

This study reports the first crystal structure of a class E sortase, the 1.93 A resolution structure of the SrtE1 enzyme from Streptomyces coelicolor. [sortase E1] (Mus musculus) PubMed

 19159.

NRT2.1 role in the nitrogen-use efficiency [NRT2.1] (Mus musculus) PubMed

 19160.

These results identified important kinases involved in P. pastoris cell growth and Alcohol Oxidase 1 Promoter (PAOX1)regulation, which could serve as valuable targets for further mechanistic studies. [Alcohol Oxidase 1] (Mus musculus) PubMed

 19161.

LptO (PG0027) is required for lipid A 1-phosphatase Activity.[LptO] (Mus musculus) PubMed

 19162.

E . faecalis WMC_RS08810 and B. cereus BC1526 are identified as lipoprotein intramolecular transacylase.[Lit] (Mus musculus) PubMed

 19163.

These data show that SpxA1 and SpxA2 have opposing roles in virulence and stress resistance, suggesting that they act coordinately to fine-tune toxin expression in response to stress.[SpxA1 and SpxA2] (Mus musculus) PubMed

 19164.

Together, these results suggested that mouse mammary tumor virus Rem uses a novel p97-dependent, Derlin-independent retrotranslocation mechanism distinct from other pathogens to avoid signal peptide ubiquitylation and proteasomal degradation.[Rem] (Mus musculus) PubMed

 19165.

We identified two genes needed for growth on GlcNAc (RON1 and NGS1) and found that mutants lacking these genes fail to induce the genes needed for GlcNAc catabolism.Thus, Ron1 is a key new component of the GlcNAc response pathway that acts as both an activator and a repressor of hyphal morphogenesis. (Mus musculus) PubMed

 19166.

Using a transposon insertion mutant with an altered Maf1 expression profile, the authors demonstrated that proper Maf1 expression is necessary for survival of the dormancy-like state induced by prolonged amino acid starvation and is needed for full recovery from other stresses that slow or stall the parasite cell cycle.[Maf1] (Mus musculus) PubMed

 19167.

These data indicate that VciB is a dimer located in the inner membrane with three transmembrane segments and a large periplasmic loop and reduces ferric iron using energy from the electron transport chain.[VciB] (Mus musculus) PubMed

 19168.

Transcription of catB is enhanced by OxyR in response to exogenous H2O2. [CatB, OxyR] (Mus musculus) PubMed

 19169.

Thus, AmBldD is a global transcriptional regulator that seems to repress the transcription of tens of genes during vegetative growth, some of which are likely to be required for sporangium formation.[AmBldD] (Mus musculus) PubMed

 19170.

crystal structures of DasR (DasR) (Mus musculus) PubMed

 19171.

he antibiofilm effect of both AlgL forms was identified in combination with piperacillin/tazobactam (PT) and the disruption effect was significantly higher in mutant AlgL combined with PT than wild-type AlgL. However, for both the wild-type and K194E/K245D/K319A mutant, the use of the AlgL enzyme alone did not show significant antibiofilm effect. (Mus musculus) PubMed

 19172.

The structure reveals that lipopolysaccharide transport proteins LptF and LptG of the LptB2FG ABC transporter each contain a transmembrane domain (TMD), a periplasmic beta-jellyroll-like domain and a coupling helix that interacts with LptB on the cytoplasmic side.[LptB2FG] (Mus musculus) PubMed

 19173.

Association with metal ions like copper and zinc at a fairly low concentration increased the protective effect of the SbDHN2 protein for lactate dehydrogenase (LDH) activity to a considerable extent.[SbDhn2] (Mus musculus) PubMed

 19174.

S. aureus acpP is a highly stable protein capable of maintaining its structure at high temperatures (Mus musculus) PubMed

 19175.

These data suggests that LdSIR2RP2 possesses NAD+-dependent ADP-ribosyltransferase activity. Gene deletion studies showed that DeltaLdSIR2RP2 null mutants had restrictive growth phenotype associated with accumulation of cells in the G2/M phase and compromised mitochondrial functioning.[LdSIR2RP2] (Mus musculus) PubMed

 19176.

NDM-1 producing Acinetobacter baumannii was isolated from patients in Ethiopia. [NDM-1] (Mus musculus) PubMed

 19177.

The results showed that gsdf expressed before sex gonadal differentiation, and the expression level increased rapidly after initiation of sex differentiation in males. [gsdf] (Mus musculus) PubMed

 19178.

Structural comparison suggests that Glu-204 in OxyR2 provides rigidity to the region that is important in H2O2 sensing, compared with the E204G structure or other OxyR proteins. [OxyR2] (Mus musculus) PubMed

 19179.

analysis of the structure and specificity of a new class E sortase (SavSrtE) annotated to perform housekeeping roles in Streptomyces avermitili [SrtE] (Mus musculus) PubMed

 19180.

The authors show that human cytomegalovirus microRNAs (miRNAs) miR-US5-1 and miR-UL112-3p target the IkappaB kinase (IKK) complex components IKKalpha and IKKbeta to limit production of proinflammatory cytokines in response to interleukin 1beta (IL-1beta) and tumor necrosis factor alpha (TNF-alpha).[miR-US5-1, miR-UL112-3p] (Mus musculus) PubMed

 19181.

these findings suggest that the biological function of TrmBL2 is not limited to modulating genome architecture and acting as a global repressor but that the protein acts additionally as a stabilizer of DNA secondary structure. [TrmBL2] (Mus musculus) PubMed

 19182.

Results identified a novel metallo-beta-Lactamase (MBL) involved in the ampicillin resistance of Streptococcus pneumonia. The mechanism of antibiotic resistance might result from, at least in part, the enzymatic degradation of penicillin-based drugs on the surface of the bacterial cell. [MBL] (Mus musculus) PubMed

 19183.

findings reveal a non-immunological role of IL-17 modulating circuit function and behavior [IL-17] (Mus musculus) PubMed

 19184.

To explore the structural basis for the observed functional changes (altered specificity, improved molecular oxygen affinity) we solved the crystal structure of the Ala420Gly mutant of PA-LOX at 1.8A resolution and compared it with the wild-type enzyme (Mus musculus) PubMed

 19185.

analysis of binding sites for ubiquinone and inhibitors in the Na(+)-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae by photoaffinity labeling [nqrA] (Mus musculus) PubMed

 19186.

the solution structure of subdomain G3 of Geobacillus stearothermophilus IF2 has been elucidated. G3 forms a core structure consisting of two beta-sheets with each four anti-parallel strands, followed by a C-terminal alpha-helix. (Mus musculus) PubMed

 19187.

establishment through fine mapping, genome sequencing, genetic complementation, and gene editing, that haploid induction in maize (Zea mays) is triggered by a frame-shift mutation in MATRILINEAL (MTL), a pollen-specific phospholipase, and that novel edits in MTL lead to a 6.7% haploid induction rate (the percentage of haploid progeny versus total progeny) (Mus musculus) PubMed

 19188.

the function of archaeal RecJ in DNA replication evolved divergently from Cdc45 despite conservation of the CMG-like complex formation between Archaea and Eukarya [RecJ2] (Mus musculus) PubMed

 19189.

analysis of two phylogenetically divergent CDP-DAG synthase (CDS) enzymes in the parasite: eukaryotic-type TgCDS1 and the prokaryotic-type TgCDS2 reside in the endoplasmic reticulum and apicoplast, respectively [CDS1 and CDS2] (Mus musculus) PubMed

 19190.

These results strongly suggest that Rob is a long-sought repressor that recognizes and binds to the TATTT motif and is an important regulator of biofilm elaboration through its control of SAOUHSC_2898 (SATF2584) and Ica protein expression in Staphylococcus aureus.[Rob] (Mus musculus) PubMed

 19191.

Integrating additional in vivo and in vitro data, the authors propose that binding of MRB8170 and/or MRB4160 onto pre-mRNA marks it for the initiation of editing and that initial binding of both proteins may facilitate the recruitment of other components of the RNA editing/processing machinery to ensure efficient editing.[MRB8170, MRB4160] (Mus musculus) PubMed

 19192.

The authors conclude that nsp15 localizes and interacts with coronavirus proteins in the replication/transcription complexes, suggesting it plays a direct or indirect role in virus replication.[nsp15] (Mus musculus) PubMed

 19193.

The role of 30S ribosomal protein s5 in spectinomycin resistance [30S ribosomal protein s5 ] (Mus musculus) PubMed

 19194.

Despite the strong association of CdaI with the new posterior cell end, the cdaI-1 mutation does not affect the patterning of the new posterior cortical organelles. (Mus musculus) PubMed

 19195.

we identify and confirm the mutations in xrep-2, xrep-3, and xrep-4 The xrep-2 gene is alh-6, an ortholog of a human gene mutated in familial hyperprolinemia. The xrep-3 mutation is a gain-of-function allele of skn-1 The xrep-4 gene is F46F11.6, which encodes a F-box-containing protein. We demonstrate that xrep-4 alters the stability of WDR-23 (xrep-1), a key regulator of SKN-1 (xrep-3). (Mus musculus) PubMed

 19196.

RpoE promote bacterial invasion and intracellular survival by regulating the expression of SPI-1 and SPI-2.[RpoE, SPI-1 and SPI-2] (Mus musculus) PubMed

 19197.

TLR2-mediated PI3K/Akt pathway ensures the transient expression of potent inflammatory mediators.[Lrp] (Mus musculus) PubMed

 19198.

This study isolated ras suppressor 1 mutant that causes spontaneous clustering of extrasynaptic Acetylcholine Receptor that are normally dispersed. (Mus musculus) PubMed

 19199.

the NMR structure of a highly aromatic (13%) protein of unknown function, Aq1974 from Aquifex aeolicus (PDB ID: 5SYQ). The unusual sequence of this protein has a tryptophan content five times the normal (six tryptophan residues of 114 or 5.2% while the average tryptophan content is 1.0%) with the tryptophans occurring in a WXW motif. (Mus musculus) PubMed

 19200.

We concluded that Sr12, or a gene closely linked to Sr12, was responsible for 'Thatcher'-derived APR in several environments and this resistance was enhanced in the presence of Lr34. (Mus musculus) PubMed

 19201.

Molecular characterization and immune protection of a new conserved hypothetical protein CHP559 of Eimeria tenella has been reported. (Mus musculus) PubMed

 19202.

Autophagy-associated protein ATG12 is required for fruiting-body formation in Sordaria macrospora. [ATG12] (Mus musculus) PubMed

 19203.

MxiA, MxiC and IpaD act together to regulate substrate selection and secretion mode in the Type III secretion systems of Shigella flexneri.[MxiA, MxiC, IpaD] (Mus musculus) PubMed

 19204.

The trimeric structure showed that the C-terminal domains form the core, which was made by inter-subunit interactions mainly through hydrophobic contacts, while the N-terminal domains containing a winged helix-turn-helix DNA binding motif were arranged around the periphery.[ArgR] (Mus musculus) PubMed

 19205.

DcUSAGT1 may influence anthocyanin biosynthesis of purple carrot taproots.[DcUSAGT1] (Mus musculus) PubMed

 19206.

Combined targeting of UBAP1 and toll-like receptor adaptors TIRAP and MyD88 by Pseudomonas aeruginosa PumA impedes both cytokine and toll-like receptor signalling, highlighting a novel strategy for innate immune evasion.[PumA] (Mus musculus) PubMed

 19207.

B. licheniformis contains three PerR subfamily proteins which can sense H2O2 by histidine oxidation not by cysteine oxidation, in addition to Fur and Zur.[PerR, Fur, Zur] (Mus musculus) PubMed

 19208.

these results provide important information for a more detailed understanding of the cofactor and substrate binding mode as well as the catalytic mechanism of SePSK, and possible similarities with its plant homologue AtXK-1. (Mus musculus) PubMed

 19209.

DiiA (SP1992) is a distinctive pneumococcal virulence factor contributing to colonization and long-term invasion in this pathogen. (Mus musculus) PubMed

 19210.

a completely new protocol for the expression and purification of milligram quantities of fully-functional, more stable and crystallizable ELIC. The use of an autoinduction media and inexpensive detergents during ELIC extraction (Mus musculus) PubMed

 19211.

we show that Enterohemorrhagic Escherichia coli could secrete a novel effector, KatN, a Mn-containing catalase, in a type VI secretion system-dependent manner (Mus musculus) PubMed

 19212.

crystal structure of CgAspAT, an aspartate aminotransferase from Corynebacterium glutamicum [CgAspAT] (Mus musculus) PubMed

 19213.

our results presented here show that FgTom1 is a new virulence factor in F. graminearum. (Mus musculus) PubMed

 19214.

study confirms that both the heme uptake system and HeuR are required for full chicken gastrointestinal tract colonization, with the heuR mutant being particularly affected during competition with wild-type C. jejuni Transcriptomic analysis identified the chu genes-and those encoding other iron uptake systems-as regulatory targets of HeuR [HeuR]. (Mus musculus) PubMed

 19215.

report that TgPKAc3 is responsible for cAMP-dependent tachyzoite maintenance while suppressing differentiation into bradyzoites, revealing one mechanism underlying how this parasite transduces cAMP signals during differentiation [Cyclic AMP-Dependent Protein Kinase Subunit 3; TgPKAc3] . (Mus musculus) PubMed

 19216.

Listeria monocytogenes InlB stimulated Met-dependent phosphorylation of mTORC1 or mTORC2 substrates, demonstrating activation of both mTOR-containing complexes.[InlB] (Mus musculus) PubMed

 19217.

This study reports the finding of a folded monomeric intermediate of Pyrococcus furiosus l-asparaginase under acidic condition. This monomer, although inactive, displayed secondary and tertiary structural features identical to the native protein and re-assembled to active dimeric form upon reversal of pH. [l-asparaginase ] (Mus musculus) PubMed

 19218.

this study reports crystal structures at 1.58-angstrom resolution of the unlinked NS2B-NS3 protease from ZIKV as free enzyme and bound to a peptide reversely oriented at the active site. (Mus musculus) PubMed

 19219.

propose that xanthine dehydrogenase regulator (XdhR) is a direct target of (p)ppGpp, and that expression of xdhABC is upregulated during the stringent response to promote purine salvage pathways, maintain GTP homeostasis and ensure continued (p)ppGpp synthesis [xanthine dehydrogenase regulator;XdhR] (Mus musculus) PubMed

 19220.

structural data provide novel insights into the architecture of invasin-family proteins and a platform for further studies towards unraveling the function of InvasinE in the context of infection and host colonization. (Mus musculus) PubMed

 19221.

Triple deletion of Lmb, AdcA, and AdcAII impaired growth and cell separation in a zinc-restricted environment. [Lmb, AdcA, and AdcAII ] (Mus musculus) PubMed

 19222.

IdsD must originate from another cell to communicate identity and that this nonresident IdsD interacts with IdsE resident in the recipient cell. [IdsD] (Mus musculus) PubMed

 19223.

We also find that a casein kinase homolog, TTBK-3, inhibits stabilization of nascent synapses in their new locations, a previously unexplored facet of structural plasticity of synapses. Our study delineates temporally distinct signaling pathways that are required for effective neural circuit refinement. (Mus musculus) PubMed

 19224.

The Ras/Rap1-specific endopeptidase (RRSP) module of the multifunctional autoprocessing repeats-in-toxins (MARTX) toxin produced by Vibrio vulnificus has sequence homology to the C1-C2 domains of PMT, including a putative MLD. (Mus musculus) PubMed

 19225.

These results indicated for the first time that the 32 kDa protein functioned as an attachment protein for the initial attachment and entry of lymphocystis disease virus, and the interaction of the 32 kDa viral attachment protein with the 27.8 kDa receptor protein in flounder gill initiated lymphocystis disease virus infection.[32 kDa viral attachment protein] (Mus musculus) PubMed

 19226.

These results indicated for the first time that the 32 kDa protein functioned as an attachment protein for the initial attachment and entry of lymphocystis disease virus, and the interaction of the 32 kDa viral attachment protein with the 27.8 kDa receptor protein in flounder gill initiated lymphocystis disease virus infection.[27.8 kDa receptor protein] (Mus musculus) PubMed

 19227.

Here the authors demonstrate the significant antiviral role of PKR against foot-and-mouth disease virus (FMDV) and report that FMDV infection inhibits PKR expression and activation in porcine kidney (PK-15) cells. The viral nonstructural protein 3C proteinase (3C(pro)) is identified to be responsible for this inhibition.[3C proteinase] (Mus musculus) PubMed

 19228.

Mp1p is a key virulence factor of T. marneffei. Mp1p mediates virulence by improving the survival of T. marneffei in macrophages [Mp1p]. (Mus musculus) PubMed

 19229.

Bradyrhizobium japonicum USDA110 MbfA and Bfr genes work in concert to manage iron and oxidative stresses. An mbfA bfr double mutant showed a loss of stress adaptation, and had a severe growth phenotype in high iron media. [mbfA] (Mus musculus) PubMed

 19230.

Over expression of NTH1, a nuclear T. cruzi DNA glycosylase, does not modify parasite viability when NTH1 transfected epimastigotes are exposed to H2O2 for 30 minutes. However, parasite survival is decreased when those parasites are submitted to a sustained production of H2O2. [NTH1] (Mus musculus) PubMed

 19231.

Findings show that the NADPH-thioredoxin reductase C (NTRC) mutant could not grow under nitrogen-fixing conditions, indicating that NTRC is an important member of antioxidant defense system[s, especially under conditions of oxidative stress: [NTRC] (Mus musculus) PubMed

 19232.

We propose that in a mutant strain compromised in reducing equivalents, the absence of an abundant and competitive substrate such as the peroxiredoxin Tpx1 has been selected as a lethality suppressor to favor RNR function at the expense of the non-essential peroxide scavenging function, to allow DNA synthesis and cell growth. (Mus musculus) PubMed

 19233.

Electrophoretic mobility shift assay revealed that these residues in teh viral RNA-dependent RNA polymerase (NS7) are important for RNA binding, particularly R396.[NS7] (Mus musculus) PubMed

 19234.

The structures of the native enzyme and of the complexes present significant differences in the active site region compared to PnpCD, the other hydroquinone 1,2-dioxygenase of known structure, and in particular they show a different coordination at the metal center. (Mus musculus) PubMed

 19235.

Sbg1 and Bgs1 physically interact and are interdependent for localization to the plasma membrane[sbg1] (Mus musculus) PubMed

 19236.

Data suggest that the CatSper channel regulates sperm motility during porcine capacitation-related events in vitro; CatSper1 is distributed over membrane of acrosomes; CatSper2 and CatSper4 are distributed over membranes of post-acrosome structures. [Catsper1, cation channel, sperm associated 1; Catsper2, cation channel, sperm associated 2; Catsper4, cation channel, sperm associated 4] (Mus musculus) PubMed

 19237.

findings demonstrate that M. tuberculosis YqgF/RuvX is a genuine Holliday junction (HJ) resolvases analogous to RuvC from E. coli [RuvX] (Mus musculus) PubMed

 19238.

roles of conserved residues in heme pocket stabilization in HmuT [HmuT] (Mus musculus) PubMed

 19239.

The authors identify calcium-binding and coiled-coil domain 2 (CALCOCO2, also known as NDP52) as a binding partner of influenza A virus PB1-F2.[PB1-F2] (Mus musculus) PubMed

 19240.

These results indicate that the stabilization derived from the local electrostatic interaction in the H2ase/cyt c3 complex overcomes the destabilization derived from the electrostatic repulsion of the overall positive charge of both proteins (Mus musculus) PubMed

 19241.

Taken together, these findings suggest that grass carp reovirus VP41 prevents the fish interferon response by attenuating the phosphorylation of MITA for viral evasion.[VP41] (Mus musculus) PubMed

 19242.

CTRP6 Is expressed abundantly in pig subcutaneous fat and up-regulated during adipocyte differentiation.[CTRP6] (Mus musculus) PubMed

 19243.

These results indicate that asymmetric conduction in wild-type M2 is due to W41 inhibition of C-terminal acid activation by H37. (Mus musculus) PubMed

 19244.

the first three-dimensional structures of the enzyme in various complexes determined to resolutions of 1.7 A or higher. Of particular significance are the external aldimine structures of WlaRG solved in the presence of either dTDP-3-amino-3,6-dideoxy-d-galactose or dTDP-3-amino-3,6-dideoxy-d-glucose. (Mus musculus) PubMed

 19245.

proteolysis by the essential FtsH protease in Escherichia coli [FtsH] (Mus musculus) PubMed

 19246.

The structural modeling and molecular dynamics simulation analyses also provide a plausible structure of the catalytic core, centered on a conserved histidine (His-26) that initiates the hydrolysis of phosphate esters, rationalizing the mutagenesis data. This conclusion can be applied generally to all bacterial UppP enzymes. (Mus musculus) PubMed

 19247.

Cloning, expression, purification, and characterisation of the HEAT-repeat domain of TOR from the thermophilic eukaryote Chaetomium thermophilum (Mus musculus) PubMed

 19248.

findings revealed that the signal peptide peptidase (SPP) SppA, an aspartyl protease involved in regulated intramembrane proteolysis (RIP), is essential for hypoxia adaptation in Aspergillus nidulans [SppA]. (Mus musculus) PubMed

 19249.

Deletion of bccpa1 had a profound effect on hyphal growth, morphogenesis, and virulence. [bccpa1] (Mus musculus) PubMed

 19250.

Functional Differentiation of Antiporter-Like Polypeptides in Complex I; a Site-Directed Mutagenesis Study of Residues Conserved in MrpA and NuoL but Not in MrpD, NuoM, and NuoN (Mus musculus) PubMed

 19251.

In this study, we identified RavK as a Dot/Icm substrate that targets the host cytoskeleton and reduces actin filament abundance in mammalian cells upon ectopic expression (Mus musculus) PubMed

 19252.

MdCHS1, MdCHS2 and MdCHS3 code for chalcone synthase family proteins exhibiting polyketide synthase activity. MdCHS1, MdCHS2 and MdCHS3 expression levels were associated with the levels of phloretin accumulate in the respective tissues. [CHS3] (Mus musculus) PubMed

 19253.

Biosynthesis of Salmonella enterica [NiFe]-hydrogenase-5 [Hyd-5] (Mus musculus) PubMed

 19254.

study revealed that while HIV-1 gp120 and Staph aureus LukED both target CCR5, they bind to different regions of the receptor, highlighting the divergence of the pathogens (Mus musculus) PubMed

 19255.

primary inositol transporter, ITR1, was functionally and structurally characterized; predicted structure contained 12 transmembrane alpha-helices with intracellular C and N termini; the apparent Km was 0.94 +/- 0.08 suggesting that myo-inositol transport in P. carinii is likely through a low-affinity, highly selective transport system [ITR1] (Mus musculus) PubMed

 19256.

most of the mutations in its propeller domain occur in two spatial clusters. Of these, one cluster is enriched in surface exposed residues which may drive PfKelch13-centered protein interactions, and the second cluster mostly contains residues which are buried and whose mutations may destabilize PfKelch13 structure. (Mus musculus) PubMed

 19257.

chondroitinase C effectively degrades and inactivates inhibitory chondroitin sulfate proteoglycans present in the endoneurial Schwann cell basal lamina and does so more specifically than chondroitinase ABC [chondroitinase C] (Mus musculus) PubMed

 19258.

gate loop is important for AcrB export activity but is not required for erythromycin binding [AcrB] (Mus musculus) PubMed

 19259.

PA subunit of influenza RNA-dependent RNA polymerase deserves constantly increasing attention due to its essential role in influenza life cycle. The experiments demonstrate a significant impact of the co-purified ions on N-terminal domain of PA activity and calculations show the importance of Mg2+ in catalysis in cells. [polymerase PA] (Mus musculus) PubMed

 19260.

The assay of catalytic efficiencies (kcat/Km) for a large substrate set revealed novel CpdB features, including very high efficiencies for 3 -AMP and 2 ,3 -cyclic mononucleotides, and previously unknown activities on cyclic and linear dinucleotides. [CpdB] (Mus musculus) PubMed

 19261.

Enzyme kinetic studies showed that CCEae3as from both Ae. aegypti and Ae. albopictus (CCEae3a_aeg and CCEae3a_alb, respectively) strongly interact with temephos oxon and slowly released the OP molecule, indicating a sequestration resistance mechanism. The enzyme is expressed at higher levels in resistant insects, primarily in malpighian tubules (MT) and nerve tissues.[CCEae3a] (Mus musculus) PubMed

 19262.

Enzyme kinetic studies showed that CCEae3as from both Ae. aegypti and Ae. albopictus (CCEae3a_aeg and CCEae3a_alb, respectively) strongly interact with temephos oxon and slowly released the OP molecule, indicating a sequestration resistance mechanism. The enzyme is expressed at higher levels in resistant insects, primarily in malpighian tubules (MT) and nerve tissues.[CCEae3a] (Mus musculus) PubMed

 19263.

Reduced tetrameric AVCP dissociated to a domain-swapped dimer and two monomers upon CO binding. Without monomers, the domain-swapped dimers formed tetramers, hexamers, and higher-order oligomers in the absence of CO, whereas the oligomers dissociated to domain-swapped dimers in the presence of CO, demonstrating that the domain-swapped dimer maintains the CO-induced subunit dissociation behavior of native ACVP. (Mus musculus) PubMed

 19264.

reinvestigated the subcellular localization of the PlsX and its role in cell division; results indicate a lack of association between PlsX and the cell division apparatus, suggesting that membrane synthesis does not need to be spatially coupled to cell division in bacteria [PlsX] (Mus musculus) PubMed

 19265.

The results of the developed IgG-ELISA showed a diagnostic specificity of 91% and a sensitivity of 82.89% and 100% for chronic and acute serum samples, respectively. In conclusion, correctly folded rtSRS3 has the potential to be used as a soluble antigen for the detection of human toxoplasmosis. (Mus musculus) PubMed

 19266.

ABI5l-lke bZIP transcription factor that is positive modulator of abscisic acid signaling - [BrABI5a; BrAB15b] (Mus musculus) PubMed

 19267.

we find that PbpA is critical for sexual development and its loss increases the production of some secondary metabolites including the carcinogen sterigmatocystin (Mus musculus) PubMed

 19268.

glpX has essential functions in gluconeogenesis [glpX] (Mus musculus) PubMed

 19269.

we discovered that the chemoreceptors TlpA and TlpD are each independent acid sensors. They enable H. pylori to respond to and escape from increases in hydrogen ion concentration near 100 nanomolar (Mus musculus) PubMed

 19270.

Three cysteine residues of host SLC52A1 are critical for porcine endogenous retrovirus-A infectivity. [ SLC52A1] (Mus musculus) PubMed

 19271.

In conclusion, the staphylococcal protease SspB inactivates galectin-3, abrogating its stimulation of oxygen radical production in human neutrophils and increasing tissue damage during skin infection.[SspB] (Mus musculus) PubMed

 19272.

P-IIc represents an embryonic gut protease with a relatively broad substrate specificity, which plays an important role in the degradation of yolk proteins at the late stage of silkworm embryogenesis.[P-IIc] (Mus musculus) PubMed

 19273.

These results suggest that the Schistosoma mansoni Smbeta-Int1/SmVKR1 signaling complex is important for differentiation and survival in oocytes of paired schistosomes (Mus musculus) PubMed

 19274.

Soluble and functional PfHsp70-3, acquired by co-expression with PfHep-1, will facilitate the biochemical characterisation of this particular Hsp70 protein and its evaluation as a drug target for the treatment of malaria. (Mus musculus) PubMed

 19275.

Results support that multiple routes along the secretory pathway operate for the detoxification of Aspergillus nidulans cells from misfolded membrane proteins and that BsdA is a key factor for marking specific misfolded cargoes [BsdA]. (Mus musculus) PubMed

 19276.

Collectively, these data indicate that phosvitin-derived peptide Pt5 regulates melanin biosynthesis via cAMP signaling pathway and has the potential to be used as a melanogenesis inhibitor in medical and cosmetic industry, a novel role ever reported [Pt5] (Mus musculus) PubMed

 19277.

Solution structure of the Cys74 to Ala74 mutant of the recombinant catalytic domain of Zoocin A has been reported. [zoocin A] (Mus musculus) PubMed

 19278.

Exogenous cAMP had no effects on the tri6 mutant but partially recovered the defect of tri10 mutant in deoxynivalenol biosynthesis.[TRI6, TRI10] (Mus musculus) PubMed

 19279.

Crystal structure of beta-glucosidase 1A from Thermotoga neapolitana has been presented. [Bgl1a] (Mus musculus) PubMed

 19280.

As a first approach to elucidating the role of BMPs in regulating fish bone formation and growth, we describe the cloning, expression profiling and promoter functional analysis of bmp6 and bmp7 in tongue sole (Cynoglossus semilaevis). The results revealed that bmp6 was predominantly expressed in the gonad, and bmp7 exhibited the highest expression level in the dorsal fin [BMP7] (Mus musculus) PubMed

 19281.

Nhx1 is not only for vacuolar fusion but also life cycles in B. bassiana. [Nhx1] (Mus musculus) PubMed

 19282.

Data suggest that, in the binuclear metal-binding active site of GpdQ, loss of hydrogen bonding from second-sphere Ser127 to metal-coordinating Asn80 has significant effect on metal binding thermodynamics that result in a resting binuclear active site with high catalytic activity. [GpdQ, glycerophosphodiesterase] (Mus musculus) PubMed

 19283.

Gly 188 has rarely been observed in hemagglutinin (HA) sequences. Since it is located within a key motif of the HA receptor binding site, this mutation may have an impact on receptor recognition and specificity. [hemagglutinin] (Mus musculus) PubMed

 19284.

Data suggest that, during assembly of active R2loxI, the Mn/Fe cofactors progress through two identifiable intermediates, as evidenced by distinct optical and EPR spectra along with differential rates of formation, decay, and kinetic isotope effects. [R2loxI, heterobimetallic Mn/Fe ligand-binding oxidase] (Mus musculus) PubMed

 19285.

The Deltatrx2 and Deltatrx1(MGG_15004) Deltatrx2(MGG_04236) mutant rarely formed appressoria on hyphal tips and were defective in invasive growth. [trx1] (Mus musculus) PubMed

 19286.

The full-length Lcd1 and its N-terminal cGMP-specific phosphodiesterases, adenylyl cyclases, and FhlA (GAF) domain form dimers in solution.[Lcd1] (Mus musculus) PubMed

 19287.

The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis and trypanosome replication [TCDC34] (Mus musculus) PubMed

 19288.

Data suggest that C-terminal binding site in Brh2 influences interaction with Dss1 which markedly alters interaction of Brh2 with Rad51; release of Dss1 from Brh2 as it binds ssDNA triggers nucleation of a short Rad51 oligomer on Brh2, which in turn promotes dissociation of Brh2 from DNA. [Dss1 = Brh2-interacting protein Dss1; Brh2 = Rad51-associated protein Brh2; Rad51 = recombinase Rad51] (Mus musculus) PubMed

 19289.

The K. pneumoniae YfgL lipoprotein mediates in outer membrane proteins biogenesis and is crucial for anti-phagocytosis and survival in vivo [YfgL]. (Mus musculus) PubMed

 19290.

These data suggest that molluscum contagiosum virus MC159 competitively binds to NEMO to prevent cIAP1-induced NEMO polyubiquitination.[MC159] (Mus musculus) PubMed

 19291.

The receptor-like cytoplasmic kinase BSR1 mediates chitin-induced defense signaling in rice cells. [BSR1] (Mus musculus) PubMed

 19292.

Data suggest that Mac1 is involved in laccase activity, superoxide dismutase activity, and intracellular copper homeostasis; Mac1 specifically binds to promoter region of ctrC (chymotrypsin C) and regulates expression of Ctrt1 (copper transporter); Mac1 also appears to function as a virulence factor in A1160 strain of Aspergillus fumigatus. [Mac1, copper-sensing transcription factor] (Mus musculus) PubMed

 19293.

Study characterized two members of the Nkx5 family, Nkx5.3 and SOHo, in Xenopus laevis; both Nkx5.3 and SOHo are expressed in the developing eye, ear, lateral line system, and cranial neurons as determined by in situ hybridization. [Nkx5.3, SOHo] (Mus musculus) PubMed

 19294.

Results provide unequivocal evidence that binding to extracellular matrices mediated by Cnm is an important virulence attribute of S. mutans and confirm the usefulness of the L. lactis heterologous system for further characterization of bacterial virulence factors. [Cnm] (Mus musculus) PubMed

 19295.

TIF2 and TRF have roles in suppressing Variant Surface Glycoprotein antigen switching [TIF2, TRF] (Mus musculus) PubMed

 19296.

The NMR solution structure and function of RPA3313 describe it as a putative ribosomal transport protein. [RPA3313] (Mus musculus) PubMed

 19297.

Crystal structure of the archaeosine synthase QueF-like and its biocatalytic mechanism has been described. [QueF-L] (Mus musculus) PubMed

 19298.

RpoS is required for growth of V. cholerae on insoluble chitin. [RpoS] (Mus musculus) PubMed

 19299.

X-ray crystal structure of cytochrome P450 monooxygenase CYP101J2 from Sphingobium yanoikuyae strain B2 has been presented. [CYP101J2] (Mus musculus) PubMed

 19300.

Identified an A. actinomycetemcomitans strain isolated from two patients with advance chronic periodontitis that has a regular cdtABC operon, which, however, codes for a unique, shorter, variant of the CdtB subunit. (cytolethal distending toxin subunit B) (Mus musculus) PubMed

 19301.

A nonribosomal peptide synthetase, CctN, is responsible for the synthesis of cyclochlorotine. [CctN] (Mus musculus) PubMed

 19302.

TaGID2s, novel positive regulators of the GA response, recognize RHT-1s in the LHRII motif resulting in poly-ubiquitination and degradation of the DELLA protein.[TaGID2] (Mus musculus) PubMed

 19303.

Here we demonstrate that FIV, a pathogenic lentivirus in domestic cats, antagonizes feline APOBEC3 proteins by both Vif and a viral protease [vif, protease] (Mus musculus) PubMed

 19304.

a small molecule, BP-15, that specifically binds the C-terminal regulatory domain of AphB and increases its activity. Interestingly, molecular docking predicts that BP-15 does not bind in the putative primary effector-binding pocket located at the interface of RD-I and RD-II as in other LTTRs, but rather at the dimerization interface. (Mus musculus) PubMed

 19305.

These data reveal that the N-terminal domain (NTD) of Staphylococcus aureus HPF (RaiA) binds to the 30S ribosomal subunit as observed for shorter variants of HPF in other species. The C-terminal domain of HPF protrudes out of each ribosome in order to mediate dimerization.[HPF] (Mus musculus) PubMed

 19306.

Expression and activity analysis of fructosyltransferase from Aspergillus oryzae has been reported. [fructosyltransferase] (Mus musculus) PubMed

 19307.

the results from these studies indicate not only that 8-formyl FAD forms spontaneously and results in the active form of FOX but also that its autocatalytic formation is dependent on a nearby arginine residue, R87. Thus, this work describes a new enzyme cofactor and provides insight into the little-understood mechanism of enzyme-mediated 8alpha-flavin modifications. (Mus musculus) PubMed

 19308.

the RccR and HexR regulators enable the rapid coordination of multiple aspects of primary carbon metabolism, in response to levels of a single key intermediate. (Mus musculus) PubMed

 19309.

demonstrated that NADH oxidase is required for S. suis 2 infection; NADH oxidase activity has a key role in oxidative stress tolerance and a secondary role in virulence; results reveal NADH oxidase plays an important part in SpxA1 function and provide a new insight into the pathogenesis of S. suis 2 [NADH oxidase] (Mus musculus) PubMed

 19310.

FipB appears to act as a chaperone that facilitates proper folding and conformation of the Type Six Secretion System (T6SSS) components [FipB] (Mus musculus) PubMed

 19311.

Molluscum contagiosum virus MC005 inhibited NF-kappaB proximal to the IkappaB kinase (IKK) complex, and unbiased affinity purification revealed that MC005 interacts with the IKK subunit NEMO (NF-kappaB essential modulator).[MC005] (Mus musculus) PubMed

 19312.

The VPS27 deletion mutant (DeltaFgvps27) exhibited a reduction in growth rate, aerial hyphae formation and hydrophobicity.[VPS27] (Mus musculus) PubMed

 19313.

9S-Dioxygenase-allene oxide synthase (9S-DOX-9S-AOS) has been purified and mutated. Tyr414 of 9S-DOX-AOS catalyzes hydrogen abstraction in analogy with cyclooxygenases. Cys1051 is the critical heme thiolate ligand for 9S-AOS catalysis. [9S-Dioxygenase-allene oxide synthase] (Mus musculus) PubMed

 19314.

trafficking of PfExp1 to the PVM is independent of the folding state of the protein and also continues unabated upon inactivation of the PVM translocon Plasmodium Translocon of Exported proteins. [PfExp1] (Mus musculus) PubMed

 19315.

CgTpo1_1 and CgTpo1_2 appear to play an important role in the virulence of C. glabrata infections, being at the cross-road between multidrug resistance and pathogenesis. [CgTpo1_1] (Mus musculus) PubMed

 19316.

Energy-dispersive X-ray spectroscopy and anomalous X-ray scattering data show that YfeA is polyspecific and can alter its substrate specificity. Additionally, this report documents the discovery of a novel surface metal-binding site that prefers to chelate zinc but can also bind manganese. [YfeA] (Mus musculus) PubMed

 19317.

Characterization of AKR4C15, a novel member of aldo-keto reductases, in comparison with other rice aldo-keto reductases, has been reported. [AKR4C15] (Mus musculus) PubMed

 19318.

Here the present a cryo-EM structure of the Bacillus subtilis hibernating 100S ribosome, revealing that the C-terminal domain of LHPF (YvyD) occupies a site on the 30S platform distinct from RMF. Moreover, unlike Escherichia coli RMF, the C-terminal domain of LHPS is directly involved in forming the dimer interface, thereby illustrating the divergent mechanisms by which 100S formation is mediated in the majority of bacter (Mus musculus) PubMed

 19319.

investigated the malate-quinone and L-lactate-quinone oxidoreductases (Mqo and Lqo) both of which are critical during NO-stress for the combined utilization of peptides and l-lactate; a modelled Mqo/Lqo structure to define the catalytic and substrate-binding residues [Mqo, Lqo]. (Mus musculus) PubMed

 19320.

Andrimid biosynthesis in Serratia is regulated by Hfq and AdmX. [AdmX, Hfq] (Mus musculus) PubMed

 19321.

findings demonstrate that the enzymatic activities of the LdIMPDH and LmGMPR are regulated by the differential binding of allosteric effectors ATP and GTP to the cystathionine-beta-synthase domain domains of their respective enzymes [GMPR] (Mus musculus) PubMed

 19322.

Results indicate that HPr might play an important role in the transient upregulation of capsule and pili genes by transducing a signal in response to host cell contact to the transcription regulator CrgA. [Hpr, CrgA] (Mus musculus) PubMed

 19323.

The biofilm phenotype was reversed by inactivation of CiaRH or by the addition of competence stimulating peptide, the production of which is blocked by CiaRH activity. Competition assays showed that the enhanced biofilm phenotype also corresponded to increased oral colonization in mice. Thus the interaction between SdbA, CiaRH and ComDE affects biofilm formation both in vitro and in vivo (SdbA, CiaR and CiaH). (Mus musculus) PubMed

 19324.

This study describes a combined structural and functional investigation of WbkC from Brucella melitensis. Four high resolution X-ray structures of WbkC were determined in various complexes to address its active site architecture. Unexpectedly, the quaternary structure of WbkC was shown to be different from that previously observed for other sugar N-formyltransferases. [WbkC] (Mus musculus) PubMed

 19325.

These results suggested that the rice gene HLH068 and the Arabidopsis gene HLH112 share partially redundant functions in the regulation of abiotic stress responses but have opposite functions to control flowering in Arabidopsis.[HLH068] (Mus musculus) PubMed

 19326.

The ascorbate bound to MauG was shown to accelerate the rates of both electron transfers to the hemes and proton transfers to hemes which occur during the multistep autoreduction to the diferric state which is accompanied by oxidative damage.[MauG] (Mus musculus) PubMed

 19327.

The reaction catalyzed by E. coli ribonucleotide reductase composed of alpha and beta subunits that form an active alpha2beta2 complex is a paradigm for proton-coupled electron transfer processes in biological transformations. This study provides spectroscopic evidence for a H Bond Network at Y356 Located at the Subunit Interface of Active E. coli Ribonucleotide Reductase. [ribonucleotide reductase] (Mus musculus) PubMed

 19328.

CLD1 overexpression in the suppressible coq7 mutants restored the ratio of 5-demethoxy Q6 to Q6 toward wild type levels.[Cld1, Coq7] (Mus musculus) PubMed

 19329.

this identifies REG9.1 as a regulator of developmental cell fate, controlling the expression of Trypanosoma brucei-specific molecules elevated during transmission (Mus musculus) PubMed

 19330.

p17 suppresses both CDK1 and Plk1functions, disrupts vimentin phosphorylation, causes G2/M cell cycle arrest and thus benefits virus replication.[p17] (Mus musculus) PubMed

 19331.

PfPuf1 is important for the differentiation and maintenance of gametocytes, especially female gametocytes.[PfPuf1] (Mus musculus) PubMed

 19332.

MoGls2 is a key protein for the growth and development of M. oryzae, involving in the regulation of asexual/sexual development, stress response, cell wall integrity and infectious growth.[MoGls2] (Mus musculus) PubMed

 19333.

trehalase contributes to alleviate bacterial virulence and that inability for trehalose hydrolysis may promote higher Xanthomonas citri subsp. citri infectivity.[Trehalase] (Mus musculus) PubMed

 19334.

SlmA is a member of the TetR family of proteins, which are generally transcriptional repressors. In vitro, we find that SlmA binds directly to the chb operon promoter, and in vivo, we show that this interaction is required for transcriptional activation of this locus and for chitobiose utilization (Mus musculus) PubMed

 19335.

The objective of this study was to determine whether contemporary pharyngeal emm1 Group A Streptococcus(GAS) isolates have a reduced propensity to acquire CovRS mutations in vivo compared with invasive emm1 GAS and whether emm3, emm12, and emm28 GAS acquire CovRS mutants in mouse infection.[emm1, emm12, CovRS] (Mus musculus) PubMed

 19336.

YnfE signal peptide residues L24 and A28 were shown to be important for assembly of an active selenate reductase.[YnfE] (Mus musculus) PubMed

 19337.

This study showed that the down-regulation of the STAY GREEN RICE gene and in vivo repression of its promoter by OsGATA12, which suggests a transcriptional repression function for a GATA transcription factor for prolonging the onset of senescence in cereals.[GATA12] (Mus musculus) PubMed

 19338.

Bsr-d1 encodes a C2H2-type transcription factor, which is directly regulated by a MYB family transcription factor. These 2 transcription factors regulate expression of H2O2-degradation enzymes to accomplish resistance to Magnaporthe oryzae, constituting a novel mechanism employed by rice blast resistance in Digu rice. (Mus musculus) PubMed

 19339.

Thus, the authors show that DhRpn4 is the activator for proteasomal genes.[Rpn4] (Mus musculus) PubMed

 19340.

pombe Atg24 forms a homo-oligomer and acts redundantly with Atg20 and Atg24b, and the latter two proteins can form a hetero-oligomer.[Atg20, Atg24] (Mus musculus) PubMed

 19341.

A gold-based sensor with an integrated counter and an Ag/AgCl reference electrode was first selected and characterised and then used to develop the immunosensor for PfHRP 2, which enables a low cost, easy to use, and sensitive biosensor for malaria diagnosis. (Mus musculus) PubMed

 19342.

EHD physically interacts with DymA.[EHD, Dynamin] (Mus musculus) PubMed

 19343.

LpxH is essential for growth in A. baumannii ATCC19606 [LpxH] (Mus musculus) PubMed

 19344.

A positive role of LrtA protein in post-stress survival is proposed.[LrtA] (Mus musculus) PubMed

 19345.

Cnm and Cbm-positive S. mutans strains exhibit high colonization in dental pulp.[Cnm, Cbm] (Mus musculus) PubMed

 19346.

a transmembrane domain of pPT is likely to act as a recessed signal anchor to direct the protein into the endomembrane system, and that a tyrosine in the cytosolic N-terminus of the protein is essential for targeting.[pPT] (Mus musculus) PubMed

 19347.

Biosynthesis of ubiquinone includes series of enzymatic steps in which benzene ring undergoes a series of modifications (prenylation, decarboxylation, methylation, hydroxylation). Data suggest nonenzymatic biogenesis factors are also required for ubiquinone biosynthesis in Escherichia coli/Salmonella enterica: ubiK and UbiJ. (ubiK, aerobic ubiquinone synthesis protein K; UbiJ, aerobic ubiquinone synthesis protein J) (Mus musculus) PubMed

 19348.

Additionally, phlA transcript levels were decreased 6-fold in bacteria lacking cysE and were restored with added cysteine, indicating a role for cysteine-dependent transcriptional regulation of Serratia marcescens phospholipase activity.[phlA, cysE] (Mus musculus) PubMed

 19349.

the control of eEF1A levels is important for the maintenance of a number of cell functions beyond translation and that its de-regulation might contribute to its oncogenic properties.[eEF1A] (Mus musculus) PubMed

 19350.

Biosynthesis of ubiquinone includes series of enzymatic steps in which benzene ring undergoes a series of modifications (prenylation, decarboxylation, methylation, hydroxylation). Data suggest nonenzymatic biogenesis factors are also required for ubiquinone biosynthesis in Escherichia coli/Salmonella enterica: ubiK and UbiJ. (ubiK, aerobic ubiquinone synthesis protein K; UbiJ, aerobic ubiquinone synthesis protein J) (Mus musculus) PubMed

 19351.

Data suggest copper transporters (Ctr4, Ctr5, Ctr6), copper sensor Cuf1, and superoxide dismutase 1 (SOD1) are involved in spore outgrowth; Ctr4/Ctr6 are required for copper-dependent activation of SOD1 during sporulation; spores lacking Ctr4, Ctr5, and Cuf1 exhibit arrest of outgrowth. [Ctr4, copper transporter 4; Ctr5, copper transporter 5; Ctr6, copper transporter 6; Cuf1, copper sensor 1; SOD1, superoxide dismutase 1] (Mus musculus) PubMed

 19352.

These results highlight a novel role for complement and the Cpb1-C3-C3aR pathway in proinflammatory signaling, caspase-11 cell death, and sepsis severity. (Mus musculus) PubMed

 19353.

Taken together, the findings indicate towards a crucial role played by the tissue-specific alternative splicing and relative abundance of the PCS2 gene during heavy metal(loid) stress mitigation in rice plant.[PCS2] (Mus musculus) PubMed

 19354.

Asi1 is rapidly turned over (t1/2</=30 min). Its turnover depends on ubiquitin-mediated degradation by nucleus-localized proteasomes, exhibiting a clear requirement for the E2 ubiquitin-conjugating enzyme Ubc7, Cue1 and the AAA ATPase Cdc48 and co-factor Ubx1.[Asi1, Cdc48, Ubx1] (Mus musculus) PubMed

 19355.

These results show that CyuA is the major anaerobic cysteine-catabolizing enzyme in both Escherichia coli and Salmonella enterica, and it is proposed that anaerobic cysteine catabolism can contribute to coordination of sulfur assimilation and amino acid synthesis.[CyuA] (Mus musculus) PubMed

 19356.

Taken together, the present study reveals that T80 phosphorylation of influenza A virus NS1 reduced virus replication through controlling RIG-I-mediated interferon production and viral ribonucleoprotein activity.[NS1] (Mus musculus) PubMed

 19357.

These results demonstrate that SAUR45 is involved in plant growth by affecting auxin synthesis and transport through the repression of other proteins.[SAUR45] (Mus musculus) PubMed

 19358.

The authors conclude that LtgA and LtgD protect Neisseria gonorrhoeae from neutrophils by contributing to envelope integrity and limiting bacterial exposure to select granule-localized antimicrobial proteins.[LtgA, LtgD] (Mus musculus) PubMed

 19359.

hese results suggest that the 1,920-bp GhAO1 promoter is a functional sequence with a potential effect on fiber cell development, mediated by TGA-element containing sequences, via the auxin-signaling pathway. (Mus musculus) PubMed

 19360.

PROKR2. Light-dependent, Prok2-induced sedation requires prokineticin receptor 2 (prokr2) and is strongly suppressed in galn mutants. (Mus musculus) PubMed

 19361.

the effects of Rht-B1b and Rht-D1b on Type I Fusarium head blight susceptibility and reducing Anther extrusion, is reported.[Rht-B1b and Rht-D1b] (Mus musculus) PubMed

 19362.

cytoplasmic domain (CTD) binding to aldolase may be dynamically modulated by phosphorylation, and there may be competition for aldolase binding between different CTDs.[Aldolase] (Mus musculus) PubMed

 19363.

these observations support a central role for the Leishmania DDX3 homolog in preventing reactive oxygen species-mediated damage and in maintaining mitochondrial protein quality control. (Mus musculus) PubMed

 19364.

Toxoplasma gondii ZNF2 may be crucial to ensure the correct polyA+ mRNA nuclear export, a function that is conserved in Pplasmodium falciparum.[ZNF2] (Mus musculus) PubMed

 19365.

PmtA is a key component of Group A Streptococcus (GAS) antioxidant defenses and contributes significantly to GAS virulence. PmtA is a P1B4-type ATPase that functions as an Fe(II) exporter and aids GAS defenses against iron intoxication and oxidative stress. [PmtA] (Mus musculus) PubMed

 19366.

the oppD2 gene may play a significant role in pathogenicity, though it is not essential for colonization and persistence [oppD] (Mus musculus) PubMed

 19367.

Dictyostelium deficient in the DNA repair nuclease Xpf (xpf(-)) display a severe and specific growth defect when feeding on bacteria.[Xpf] (Mus musculus) PubMed

 19368.

the functional interplay between fission yeast Dis1, a member of the XMAP215/TOG family, and Mal3, an EB1 protein, was studied.[Dis1, Mal3] (Mus musculus) PubMed

 19369.

function and expression of XIP1 [XIP1] (Mus musculus) PubMed

 19370.

Crystal structure of dibenzothiophene sulfone monooxygenase BdsA from Bacillus subtilis WU-S2B has been reported. [BsdA] (Mus musculus) PubMed

 19371.

OsChia2a exhibited significant antifungal activity. It appears that loop III connected to the beta-stranded region is important for (GlcNAc)n binding, but is not essential for antifungal activity. (Mus musculus) PubMed

 19372.

These results demonstrate that, by ShlA expression, Serratia triggers a Ca(2)(+) signal that reshapes cytoskeleton dynamics and ends up pushing the Serratia-containing vacuoles load out of the cell, in an exocytic-like process.[ShlA] (Mus musculus) PubMed

 19373.

Genetic disruption of the Plasmodium falciparum glycerol 3-phosphate acyltransferase enzyme demonstrates it is dispensable in blood stage parasites, even in conditions known to induce type II fatty acid synthesis.[glycerol 3-phosphate acyltransferase] (Mus musculus) PubMed

 19374.

Upregulation of miR-124 expression corresponded to decreased expression of its target, DNM2, in the Japanese encephalitis virus -infected PK15 cells. [Mir-124] (Mus musculus) PubMed

 19375.

The ESX-1 secretion system upregulates the transcription of autophagy genes, and stimulates autophagosome formation and recruitment to the mycobacteria-containing vacuole.[ESX-1] (Mus musculus) PubMed

 19376.

Cyp40 null mutant showed upregulation of various stress proteins and intrinsic homeostatic stress.[Cyp40] (Mus musculus) PubMed

 19377.

The sequence analysis revealed that the opening reading frame (ORF) of EaMIC3 was 2,607 bp and encoded a protein of 868 amino acids with 93.04 kDa. [MIC3] (Mus musculus) PubMed

 19378.

the knockdown of nucleoporins NPP-10, NPP-13 and NPP-20 in Caenorhabditiselegans affects early steps in centromere formation and sister centromere resolution, and results in severe chromosomal defects in the early embryo.[NPP-10, NPP-13] (Mus musculus) PubMed

 19379.

Data suggest that FREP1-mediated Plasmodium falciparum transmission to mosquitoes is a conserved pathway and that targeting the FBG (fibrinogen-like) domain of FREP1 from Anopheles gambiae will limit the transmission of multiple Plasmodium species to multiple Anopheles species. [FREP1, fibrinogen-related protein 1] (Mus musculus) PubMed

 19380.

Residue N108 of Tas is important for binding to bovine foamy virus promoters and has a major role in bovine foamy virus replication. [Tas] (Mus musculus) PubMed

 19381.

Data suggest that enterohemorrhagic Escherichia coli growth on host mucins is enabled by Bacteroides fragilis sialidase (Neu) and EstA, a sialate O-acetylesterase acting on glycosidically linked sialate-O-acetylesterase substrates, particularly at neutral pH. (EstA = sialate O-acetylesterase; Neu = neuraminidase, sialidase) [EstA, sialate O-acetylesterase; Neu, neuraminidase, sialidase] (Mus musculus) PubMed

 19382.

These results identified EseH, the ETAE_1757 encoded protein, as a critical type III secretion system effector that contributes to virulence by targeting MAPK signalling during Edwardsiella piscicida infection.[EseH] (Mus musculus) PubMed

 19383.

BnSnRK2.4-1C, an SnRK preferentially expressed in guard cells, is redox-regulated with potential roles in guard cell signal transduction.[BnSnRK2.4-1C] (Mus musculus) PubMed

 19384.

These results demonstrate that the Paracoccidioides brasiliensis histidine kinase DRK1 gene is differentially expressed during the dimorphic mycelium-yeast transition.[DRK1] (Mus musculus) PubMed

 19385.

UL7 attenuates the virulence of herpes simplex virus 1 by reducing the modulation of alpha-4 gene transcription.[alpha-4] (Mus musculus) PubMed

 19386.

Evidence is presented that PadA and Hsa are each reliant on the other's active presentation on the bacterial cell surface, suggesting cooperativity in functions impacting both colonization and pathogenesis.[PadA, Hsa] (Mus musculus) PubMed

 19387.

The gene tagged in the suppressor mutants encodes a newly unidentified HECT ubiquitin ligase that is homologous to mammalian HERC1, but harbours a pleckstrin homology domain.[HECT ubiquitin ligase] (Mus musculus) PubMed

 19388.

Mirn122 microRNA, mouse. miR-122*, the passenger strand of miR-122, regulates the activity of p53 by targeting Mdm2. Importantly, similarly to miR-122, miR-122* is significantly down-regulated in human hepatocellular carcinoma. We therefore propose that miR-122* is an important contributor to the tumor suppression activity previously attributed solely to miR-122 (Mus musculus) PubMed

 19389.

These results suggest that MEL1 plays important roles in epigenetic large-scale meiotic chromosome reprogramming to promote faithful homologous recombination and synapsis during rice meiosis.[MEL1] (Mus musculus) PubMed

 19390.

results suggest that DeltassnA represents an attractive candidate for designing an attenuated live vaccine against SS2. (Mus musculus) PubMed

 19391.

Overexpressing the Janus kinase Hop inhibits infection with several dengue virus . [Hop] (Mus musculus) PubMed

 19392.

The authors identified Importin-alpha1 to bind to Coxiella burnetii AnkG and concluded that binding of AnkG to p32 and Importin-alpha1 is essential for its migration into the nucleus.[AnkG] (Mus musculus) PubMed

 19393.

These results suggest that BnLATE is a negative regulator of lignin biosynthesis in the yellowing silique walls, and promotes silique-shattering resistance in B. napus through restraining the polymerization of monolignols and lignin. (Mus musculus) PubMed

 19394.

the P39 peptide is a structural mimic of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) on the sporozoite surface.[GAPDH] (Mus musculus) PubMed

 19395.

Mkh1 localization to cell tips is important for transmitting upstream signaling to Pmk1, and Skb5 spatially regulates this process.[Skb5, Pmk1, Mkh1] (Mus musculus) PubMed

 19396.

these results demonstrate an adaptation by S. aureus to obesity/type 2 Diabetes with increased expression of clfA that is associated with the hypercoagulable state of the host and increased virulence of S. aureus. [Clumping Factor A (ClfA] (Mus musculus) PubMed

 19397.

Report structural basis for noncanonical substrate recognition of cofilin-1/LIMK1 to regulation actin cytoskeleton dynamics. (Mus musculus) PubMed

 19398.

product release from these HsHGPRT and PfHGXPRT mutants [HGXPRT] (Mus musculus) PubMed

 19399.

PerR-mediated control of Fe(II) efflux by PmtA is important for bacterial defense against oxidative stress. PmtA represents an exemplar for an Fe(II) efflux system in a host-adapted Gram-positive bacterial pathogen. [PmtA] (Mus musculus) PubMed

 19400.

Myoblast proliferation is enhanced by increasing S-nitrosothiols, and regulated by GSNOR activity, independently of cyclic GMP production and signaling. [GSNOR] (Mus musculus) PubMed

 19401.

LptC may have evolved to improve the performance of an ancestral six-component Lpt machine [LptC][LptF] (Mus musculus) PubMed

 19402.

These results strongly prove that the yeast Kluyveromyces lactis does indeed possess a functional linker histone gene thus entailing the evolutionary preservation and significance of linker histones.[LH1] (Mus musculus) PubMed

 19403.

These results suggest that the glycerol transporter GT1 may participate in the process of alcohol oxidase AOX1 inhibition in glycerol medium.[GT1, AOX1] (Mus musculus) PubMed

 19404.

Overexpression of the ATP-binding cassette transporter CDR1 in Saccharomyces cerevisiae ADDelta caused multidrug resistance similar to that of cells overexpressing Candida albicans CDR1.[CDR1] (Mus musculus) PubMed

 19405.

the six-transmembrane K(+) channel KCN11 in Chlamydomonas is exclusively localized to contractile vacuole.[KCN11] (Mus musculus) PubMed

 19406.

H. pylori infection of rhesus macaques is under independent selective pressure for loss of babA and overexpression of babB. Overexpression of BabB enhances H. pylori fitness. Loss of BabA expression in rhesus monkeys is not dependent on its capacity to bind blood group antigen Leb. [BabA; BabB] (Mus musculus) PubMed

 19407.

Prostaglandin D2 actions in guinea pig out-flow region and the distribution of DP1 /DP2 receptors, were investigated.[DP1, DP2] (Mus musculus) PubMed

 19408.

Findings suggest a role for c-di-GMP acting through BrtA/LapD/LapG to modulate biofilm formation: [BrtA, LapD and LapG] (Mus musculus) PubMed

 19409.

Autophagy-associated proteins, including the Beclin 1 homolog BEC-1 and the Atg8/LC3-family members LGG-1 and LGG-2, localize around the midbody phagosome and are required for midbody degradation.[LGG-2] (Mus musculus) PubMed

 19410.

Pex35 functionally interacts with the vesicle-budding-inducer Arf1.[Pex35] (Mus musculus) PubMed

 19411.

haploinsufficiency of LmCA1 and/or LmCA2 renders the parasite acid-susceptible, thereby unravelling a carbonic anhydrase-mediated pH homeostatic circuit in Leishmania cells.[LmCA1, LmCA2] (Mus musculus) PubMed

 19412.

Growth phase-dependent control of R27 conjugation is mediated by the plasmid-encoded TrhR/TrhY-HtdA and the cAMP. [TrhR,TrhY,HtdA] (Mus musculus) PubMed

 19413.

Data suggest that SodA of Leishmania mexicana amazonensis is a mitochondrial isoenzyme that promotes virulence and is essential for trypanosomatid survival; SodA appears to promote virulence by protecting parasites against mitochondrion generated oxidative stress and by initiating ROS-mediated signaling mechanisms required for differentiation of infective forms. [SodA, iron-dependent superoxide dismutase] (Mus musculus) PubMed

 19414.

Data suggest that sodium ion binding or calcium ion binding to NCX differentially stabilizes the outward-facing and inward-facing conformational states as the protein sits in the cell membrane; these distinctly stabilized ion-occluded states may control ion release dynamics at opposite sides of the cell membrane. [NCX, Na+/Ca2+ exchanger] (Mus musculus) PubMed

 19415.

findings demonstrate that the efflux transporter of the siderophore staphyloferrin A (SA) contributes to the ability of S. aureus to replicate in abscesses and epithelial cells [staphyloferrin A (SA)]. (Mus musculus) PubMed

 19416.

Alteration and remodeling of adenylation active site are interconnected, intrinsic features of uba1 and contribute to adenylation/thioester formation exhibited by activated uba1 upon binding of ubiquitin/ubc4. (uba1 = ubiquitin activating enzyme E1; ubc4 = ubiquitin-conjugating enzyme E2 4) [uba1, ubiquitin activating enzyme E1; ubi4 = ubiquitin; ubc4 = ubiquitin-conjugating enzyme E2 4] (Mus musculus) PubMed

 19417.

Data suggest that spt1 and spt2 are functional, homodimeric serine palmitoyltransferases localized to endoplasmic reticulum; spt1/spt2 exhibit N-terminal extensions with transmembrane regions; spt1/spt2, conserved throughout Apicomplexa, were likely obtained via lateral gene transfer from a prokaryote with subsequent gene duplication. [spt1 = serine palmitoyltransferase 1; spt2 = serine palmitoyltransferase 2] (Mus musculus) PubMed

 19418.

Data suggest that GTPase Sar1-mediated secretion of gp63 is necessary for survival of L donovani in human macrophages; GTP-bound Sar1 specifically binds to Sec23, which binds, in turn, with Sec24(1-702) to form a pre-budding complex as prelude to formation of COPII-coated vesicles and secretion of virulence factor gp63. [Sar1] (Mus musculus) PubMed

 19419.

PetC3 affects processes in the periplasmic compartment that only indirectly influence photosynthetic electron transport in cyanobacterium Synechocystis PCC 6803. (Mus musculus) PubMed

 19420.

both skissr and sGnRH3 were also expressed in the saccus vasculosus (SV), an organ only found in fish. The SV might be a seasonal sensor regulating reproduction in addition to the hypothalamus (Hyp). (Mus musculus) PubMed

 19421.

HprA1 protein contributes to hydrogen peroxide tolerance in L. casei by binding to iron in the cells and preventing the formation of a hydroxyl radical. ]HprA1] (Mus musculus) PubMed

 19422.

Significant increase in expression of CaTPS during strawberry fruit infection. [TPS] (Mus musculus) PubMed

 19423.

Two ferritin subfamilies have similar tertiary structure yet distinct quaternary structure: maxi-ferritins (4-fold symmetry axes, E coli bfr) and mini-ferritins (3-fold axes, E coli dps). Data suggest chimeric dps/bfr maxi-model forms assemble into cages homologous to mini-ferritins; E-domains (from bfr) are flipped external to cage at 3-fold axes. [bfr, bacterioferritin; dps, Fe-binding and storage protein] (Mus musculus) PubMed

 19424.

The results provide evidence that OsMYBR1 is involved in mediating plant responses to abscisic acid and drought. [MYBR1] (Mus musculus) PubMed

 19425.

Compared with the wild-type (4.42+/-0.58x10-4), the DeltaspxA2 mutant showed decreased transformation efficiency (0.07+/-0.03x10-4). Furthermore, SpxA2 was able to down-regulate endogenous H2O2 generation by repressing pox expression.[SpxA2] (Mus musculus) PubMed

 19426.

STP1 mediated foliar uptake of the glucose-fipronil conjugate. [STP1] (Mus musculus) PubMed

 19427.

AhpC is regulated negatively by OxyR1 and positively by RpoE2. [AhpC, OxyR1, RpoE2] (Mus musculus) PubMed

 19428.

Crystal structure and functional characterization of an esterase from Exiguobacterium antarcticum has been reported. [esterase] (Mus musculus) PubMed

 19429.

After secretion of nisin, the nisin leader peptide is cleaved by leader peptidase NisP, resulting in active nisin. Data suggest NisP exhibits sequence-based cleavage activity/substrate specificity (GASPR|IT); at least one lanthionine ring (from post-translational protein processing of nisin) is crucial for substrate recognition/cleavage. [nisin, cyclic polypeptide antibiotic nisin; NisP, leader peptidase NisP] (Mus musculus) PubMed

 19430.

the prion-like protein Jub6p is involved in the regulation of chromatin structure in the ciliated protozoan Tetrahymena thermophile.[Jub6p] (Mus musculus) PubMed

 19431.

Study provides a pKa determination for the active-site side chains of photoactive yellow protein (PYP) and showed that there are no chemical-shift changes observed for the active-site residues in the pH range 3.4-11.4, demonstrating that the ground state of PYP is completely insensitive to pH in the region where the protein is chemically and structurally stable [PYP] (Mus musculus) PubMed

 19432.

metabolic dysfunction plays an important role in Sod1-mediated toxicity in both the yeast and worm models of amyotrophic lateral sclerosis. (Mus musculus) PubMed

 19433.

NS3h can cause repetitive looping of DNA. (Mus musculus) PubMed

 19434.

Rho1 rescued both Bik1 localization at the microtubule plus-ends in tub1-Glu strain and a correct Snc1 trafficking in a Bik1-dependent manner.[Bik1, Snc1, Rho1] (Mus musculus) PubMed

 19435.

In this study, we describe albicin, a novel inhibitor of the alternative pathway of complement from the salivary glands of the malaria vector, Anopheles albimanus (Mus musculus) PubMed

 19436.

SroC and MgrR sRNAs compose a coherent feed-forward loop controlling the eptB expression .[eptB, SroC and MgrR ] (Mus musculus) PubMed

 19437.

lipid remodeling mediated by the TORC2-Ypk1/Ypk2-Lem3 axis is a backup mechanism for plasma membrane (PM) anchoring of Rho1 after PM stress-induced acute degradation of phosphatidylinositol 4,5-bisphosphate.[Ypk1, Ypk2, Rho1] (Mus musculus) PubMed

 19438.

RecD2: there is notable interplay between RecD2 and RecG or RuvAB at arrested replication forks, rather than involvement in processing Holliday junctions during canonical double strand break repair. (Mus musculus) PubMed

 19439.

Unlike the well-characterized long-chain apoflavodoxins, the Streptococcus pneumoniae displays a simple two-state thermal unfolding equilibrium and binds FMN with moderate affinity. The X-ray structures of the apo and holo forms of flavodoxin differ at the Flavin Mononucleotide binding site, where substantial rearrangement of residues at the 91-100 loop occurs to permit cofactor binding. [flavodoxin] (Mus musculus) PubMed

 19440.

The inducible Pex9p-dependent import pathway provides a mechanism for the oleate-inducible peroxisomal targeting of malate synthases.[Pex9] (Mus musculus) PubMed

 19441.

the reversible membrane association of Sar1 GTPase leads to its localization being restricted to the rims of coat protein complex II-coated membranes in vivo.[Sar1] (Mus musculus) PubMed

 19442.

Data suggest that 19-year adaptation to new light environment (clearwater versus blackwater lakes in Haida Gwaii archipelago, British Columbia) involves at least seven amino acid changes in SWS2 in this species, including two changes known to cause red-shift in light absorption, and is favored in blackwater lakes but disfavored in clearwater habitat of transplant population. [SWS2, cone opsin SWS2] (Mus musculus) PubMed

 19443.

CaM-binding to KIVR was negatively regulate the KIVR activity in B. bassiana. [KIVR, CaM] (Mus musculus) PubMed

 19444.

This study showed that gelatin-coated culture protected L929 cells from TNFalpha-induced cytotoxicity.[Gelatin] (Mus musculus) PubMed

 19445.

Data suggest that CcrM exhibits a novel dual activity with single- and double-stranded DNA with unprecedented specificity ("1000-10000-fold greater than that of other methyltransferases"), and a robust discrimination against RNA; the high specificity of CcrM may be essential so that non-GANTC sites remain unmethylated. [CcrM, adenine-specific methyltransferase CcrM] (Mus musculus) PubMed

 19446.

Determined is the three-dimensional crystal structures of LC3B in complex with three different LIR motifs of RavZ from Legionella pneumophila, an intracellular pathogen that can manipulate the host autophagy system. [RavZ] (Mus musculus) PubMed

 19447.

Data suggest that BgToxA sequentially methylates N6 and N1 of 1,6-didesmethyltoxoflavin (1,6-DDMT) to form toxoflavin; in BgToxA the methyl group of S-adenosylmethionine is directed toward the p orbital of N1 in 1,6-DDMT. [BthII1283, 1,6-didesmethyltoxoflavinmethyltransferase] {GenBank: ABC33990.1} (Mus musculus) PubMed

 19448.

FAZ10 impaired the timing and placement of the cleavage furrow during cytokinesis, resulting in premature or asymmetrical cell division.[FAZ10] (Mus musculus) PubMed

 19449.

Data suggest that BthII1283 catalyzes a single methyl transfer to N1 of 1,6-didesmethyltoxoflavin (1,6-DDMT); BthII1283 contains a class I methyltransferase fold and three unique extensions used for recognition of reduced 1,6-DDMT; in BthII1283, N1 of 1,6-DDMT is hydrogen bonded to a histidine residue. [BgToxA, 1,6-didesmethyltoxoflavinmethyltransferase] {possibly GenBank: AAV52806.1} (Mus musculus) PubMed

 19450.

model proposed wherein impaired cellular respiration stimulates SaeRS via an as yet undefined signal molecule(s), resulting in increasing expression of AtlA and FnBPA and biofilm formation [SaeR, SaeS] (Mus musculus) PubMed

 19451.

study provides evidence that the LmPRL-1 phosphatase can be secreted during infection of macrophages and that it contributes to the survival of the parasite in these host cells[LmPRL-1]. (Mus musculus) PubMed

 19452.

study defined the transcriptional response to cumene hydroperoxide , identified potential virulence factors such as diguanylate cyclase as members of the OhrR regulon, and shown that C. violaceum uses the transcriptional regulator OhrR to modulate its virulence [OhrR] (Mus musculus) PubMed

 19453.

data demonstrate that the atypical response regulator AtvR is part of the repertoire of transcriptional regulators involved in the lifestyle switch from aerobic to anaerobic conditions [AtvR]. (Mus musculus) PubMed

 19454.

Cin8 clusters promote the capture of microtubules emanating from the neighboring spindle poles and mediate their antiparallel sliding.[Cin8] (Mus musculus) PubMed

 19455.

findings show that the B subunit pentamer (ArtB) of AB5 toxin binds to receptors on the surface of Vero cell, CHO cell, U937 cell, and HBMEC cell lines; ArtB induced marked vacuolation in all cell lines after 4 h of incubation [ArtB] (Mus musculus) PubMed

 19456.

Spermidine is not required for planktonic growth of Bacillus subtilis but is essential for robust biofilm formation. Data suggest spermidine functions in biofilm development by activating transcription of biofilm matrix exopolysaccharide and TasA operons through slrR. (slrR, HTH-type transcriptional regulator slrR; TasA = spore coat protein N) [slrR, HTH-type transcriptional regulator slrR; TasA, spore coat protein N] (Mus musculus) PubMed

 19457.

The tight regulation of ltf2 governs the balance between vegetative growth that allows for the colonization of the substrate and subsequent reproduction via conidia in the light. [ltf2] (Mus musculus) PubMed

 19458.

Mutation of the toxR or mshA genes reduces infection of the coral Acropora cytherea. [toxR] (Mus musculus) PubMed

 19459.

the DeltayqgF mutant had increased transformation and allelic replacement frequency and increased resistance to nalidixic acid, a DNA-damaging agent. [yqgF] (Mus musculus) PubMed

 19460.

knock-down of Kmt6 in the KMT6(kd) strain shows a drastic phenotype affecting fungal growth and development. [Kmt6] (Mus musculus) PubMed

 19461.

Processivity and the rate constant of dissociation of Human chitotriosidase (HCHT) were found to be in-between those, characteristic to processive exo-enzymes, like SmChiA and randomly acting non-processive endo-enzymes, like SmChiC. Apart from increasing the affinity for chitin, CBM had no major effect on kinetic properties of HCHT. (Mus musculus) PubMed

 19462.

Our application of Pgp3 ELISAs demonstrates a high lifetime risk of chlamydia infection among women and a large proportion of undiagnosed infections. A decrease in age-specific cumulative incidence following national implementation of opportunistic chlamydia screening has not yet been demonstrated. (Mus musculus) PubMed

 19463.

OsCRD1 protein mainly locates in chloroplast and the point mutation A96T in OsCRD1 does not change its location. Therefore, Alanine96 of OsCRD1 might be fundamental for MPEC activity, mutation of which leads to deficiency in chlorophyll biosynthesis and chloroplast development and decreases photosynthetic capacity in rice. (Mus musculus) PubMed

 19464.

Data suggest that CYP260A1, reconstituted with various ratios of mammalian adrenodoxin and adrenodoxin reductase, exhibits catalytic activity and also product pattern (from 11-deoxycorticosterone and NADPH) dependent on the redox partners. Products include: 1alpha-,14alpha-dihydroxy-11-deoxycorticosterone; 1alpha-hydroxy-11-deoxycorticosterone; 11-deoxycorticosterone-1-ene. [CYP260A1, cytochrome P-450 CYP260A1] (Mus musculus) PubMed

 19465.

Authors isolated a novel bHLH protein from cotton, named GhBEE1-Like. Protein domain analysis showed that GhBEE1-Like contained a basic domain and an HLH domain. Subcellular localization analysis revealed that GhBEE1-Like was a nuclear-localized protein. Expression pattern analysis showed GhBEE1-Like was highly expressed in floral organs. (Mus musculus) PubMed

 19466.

Results illustrate the possible involvement of HaPgp1 as a component of the protective mechanisms to plant secondary chemicals such as 2-tridecanone and to certain classes of insecticides, like abamectin. [Pgp1] (Mus musculus) PubMed

 19467.

The deletion mutation in the G4 gene resulted in a significant decrease in viral replication and production. [G4] (Mus musculus) PubMed

 19468.

the N-terminal signal peptide-like segment (1-45 bp) in hpaXm sequence is not necessary for transgene expression, bioactivity of hpaXm and resistance to Tobacooc mosaic virus in transgenic tobacco, but is required for the protein to be translocated to the cell wall.[hpaXm] (Mus musculus) PubMed

 19469.

the structure of the 2H family member LigT from Escherichia coli, was studied.[LigT] (Mus musculus) PubMed

 19470.

Nematostella has two glypican genes that are expressed in mutually exclusive ectodermal domains, NvGpc1/2/4/6 in a broad aboral domain, and NvGpc3/5 in narrow oral territory. Morpholino-mediated knockdown of NvGpc1/2/4/6 expands the expression domains of aboral marker genes and reduces oral markers at gastrula stage. Sodium chlorate phenocopies this. At planula stage, more changes in aboral marker genes occur. Gpc1. (Mus musculus) PubMed

 19471.

C. crescentus VapBC1 forms a flexible macromolecular complex able to adapt to DNA binding via conformational changes, including a dramatic reorganization of stable toxin-antitoxin interactions (vapB1 and vapC1) (Mus musculus) PubMed

 19472.

Data suggest that yeast Mlh1-Mlh3 heterodimer does not exhibit hallmarks of a canonical (structure-selective) Holliday junction resolvase/endonuclease; multiple Mlh1-Mlh3 heterodimers appear to load onto DNA to form an activated polymer that cleaves DNA. [Mlh1, mutL homolog protein 1; Mlh2, mutL homolog protein 2] (Mus musculus) PubMed

 19473.

LHCSR1 protein from Physcomitrella patens results in electron transfer between carotenoid and chlorophyll, contributing to quenching and prevention of damage to photosynthetic apparatus. (Mus musculus) PubMed

 19474.

PPX1 and PPK2 Play an important role in Mycobacterium tuberculosis metabolism, biofilm formation, and sensitivity to isoniazid in vivo. (Mus musculus) PubMed

 19475.

knockdown of FAD2-1 gene expression was accompanied by the down regulation of the expression of a number of key genes in the lipid biosynthesis pathway. [FAD-2-1] (Mus musculus) PubMed

 19476.

we report the first characterization of the orphan C-type lectin-like molecule Clr-a encoded by the Clec2e gene in the mouse NK gene complex (Mus musculus) PubMed

 19477.

This binding mode allows the 1-acyl-sn-glycerol-3-phosphate acyltransferase (PlsC) active site to acylate lysophospholipids within the membrane bilayer by using soluble acyl donors.[PlsC] (Mus musculus) PubMed

 19478.

BiFae1A showed a catalytic efficiency of 12mM s(-1) on para-nitrophenyl-acetate, and on methyl-ferulate, the value was 27 times higher. BiFae1B showed low catalytic efficiencies for both substrates.[BiFae1A, BiFae1B] (Mus musculus) PubMed

 19479.

Mutant male zebrafish deficient in the high-affinity receptor exhibit loss of attractive response to prostaglandin F2alpha[prostaglandin F2alpha] (Mus musculus) PubMed

 19480.

To understand how Cas13a is activated to cleave RNA, have the crystal structure of Leptotrichia buccalis (Lbu) Cas13a bound to crRNA and its target RNA was determined, as well as the cryo-EM structure of the LbuCas13a-crRNA complex; findings reveal how Cas13a of type VI CRISPR-Cas systems defend against RNA phages. [Cas13a] (Mus musculus) PubMed

 19481.

Ctr3 preferentially binds tRNA and 5S rRNA. A potential binding motif was identified. (Ctr3) (Mus musculus) PubMed

 19482.

Mutational analysis of the VP1 gene of strains isolated throughout North Vietnam during the 2011-2012 outbreak.[vp1] (Mus musculus) PubMed

 19483.

non-processed TbMCA2 is active when assayed with small synthetic substrates, the TbMCA2 form does not exhibit hydrolytic activity on large substrates such as azocasein, while processed TbMCA2 is able to readily digest this protein. Such differences can be relevant for understanding the physiological regulation and function of TbMCA2. (Mus musculus) PubMed

 19484.

CheY should be acetylated for ordinary adaptation time, and that the function of this acetylation in adaptation is to enable the motor to shift its rotation to clockwise (Mus musculus) PubMed

 19485.

DNA-binding mode of RcdA [RcdA] (Mus musculus) PubMed

 19486.

Thus, Clostridium tetani CtAPI represents the first d-arabinose-5-phosphate isomerase to be identified and characterized from a Gram-positive bacterium.[CtAPI] (Mus musculus) PubMed

 19487.

The authors characterize Mycobacterium smegmatis FenA as a manganese-dependent 5'-flap endonuclease homologous to the 5'-exonuclease of DNA polymerase I.[FenA] (Mus musculus) PubMed

 19488.

brpT is involved in the regulation of the gtfP-mediated exopolysaccharide synthesis and controls S. sanguinis biofilm formation.[brpT] (Mus musculus) PubMed

 19489.

These results demonstrate that the N-terminal extension of Cdr1p is phosphorylated and that N-terminal extension phosphorylation plays a major role in regulating Cdr1p and possibly other pleiotropic drug resistance transporter function.[Cdr1p] (Mus musculus) PubMed

 19490.

Genome and plasmid analysis of blaIMP-4-carrying Citrobacter freundii B38 has been presented. [IMP-4 beta-lactamase] (Mus musculus) PubMed

 19491.

Ygl8 played an important role in regulating leaf colour in rice. [Ygl8] (Mus musculus) PubMed

 19492.

PA-X protein controls virulence and immune responses of swine influenza virus in swine.[PA-X] (Mus musculus) PubMed

 19493.

Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 [Dbr1] (Mus musculus) PubMed

 19494.

Cloning, heterologous expression and biochemical characterization of a non-specific endoglucanase family 12 from Aspergillus terreus NIH2624 (Mus musculus) PubMed

 19495.

A single nucleotide change in the promoter mutp enhances fluoride resistance of Streptococcus mutans mut gene. [mut] (Mus musculus) PubMed

 19496.

Pi deficiency triggered significant increases in the relative expression levels of LPR3 and LPR5. [LPR3, LPR5] (Mus musculus) PubMed

 19497.

Collectively, these results suggest that spermidine synthase is functionally distinct from spermidine production. H. pylori may instead employ the alternative pathway for spermidine synthesis which is dominantly exploited by other human gut microbes. [spermidine synthase] (Mus musculus) PubMed

 19498.

The study presents the crystal structure of the crenarchaeal ExoIII apurinic/apyrimidinic endonuclease SisExoIII. SisExoIII comprises a two-layer core formed by 10 beta-sheets and a shell formed by 9 surrounding alpha-helices. A disulfide bond connecting beta 8 and beta 9 is formed by Cys142 and Cys215. [SisExoIII] (Mus musculus) PubMed

 19499.

This study presents the identification and characterization of a novel antimicrobial protein amp17 in M. domestica challenged with C. albicans. [amp17] (Mus musculus) PubMed

 19500.

Levels of maternal cyclin A mRNA remain constant during cell cycles of embryonic stem cells, but accessibility of cyclin A mRNA to the hybridization probe changes during each cell cycle; events underlying the fluctuating accessibility of cyclin A mRNA may be involved in regulating translational availability of cyclin A mRNA through the cell cycle or protecting nascent cyclin A protein from degradation period. [cyclin A] (Mus musculus) PubMed

 19501.

Data suggest that the chemistry of the reaction catalyzed by NadB is similar to that of typical amino acid oxidases in which transfer of the hydride from C2 of L-aspartate to FAD is rate-limiting and occurs in a concerted manner with respect to deprotonation of the alpha-amine. [NadB, L-aspartate oxidase] (Mus musculus) PubMed

 19502.

Analysis of brain transcriptomes during the transition reveals that corazonin, a neuropeptide homologous to the vertebrate gonadotropin-releasing hormone, is downregulated as workers become gamergates; authors propose that corazonin is a central regulator of caste identity and behavior in social insects. [corazonin] (Mus musculus) PubMed

 19503.

Study finds that orco mutants exhibit severe deficiencies in social behavior and fitness, suggesting they are unable to perceive pheromones; orco mutant ants also lack most of the approximately 500 antennal lobe glomeruli found in wild-type ants. results show that odorant receptors are essential for ant social organization and maybe required for olfactory processing areas in the brain. [orco] (Mus musculus) PubMed

 19504.

Lr34 mis-splicing events were also observed at adult plant age when this gene exerts its function.[Lr34]] (Mus musculus) PubMed

 19505.

lncRNA-Map2k4 is the target gene of miR-199a, and its down-regulation promotes miR-199a expression in neurons. miR-199a targeted regulation of FGF1 expression in neurons. [miR-199a] (Mus musculus) PubMed

 19506.

adenosine monophosphate (AMP) is bound to both RFs of the dimeric bacterial Kef potassium efflux system (Kef), where it plays a structural role. (Mus musculus) PubMed

 19507.

Characterization of CTX-M-140, a variant of CTX-M-14 extended-spectrum beta-Lactamase with decreased cephalosporin hydrolytic activity, from cephalosporin-resistant Proteus mirabilis has been presented. [CTX-M-140 beta-lactamase] (Mus musculus) PubMed

 19508.

overexpression of GaMYB62L suggested having developed better drought, salt and cold tolerance in transgenic Arabidopsis and thus presented it as a prospective candidate gene to achieve better abiotic stress tolerance in cotton crop (Mus musculus) PubMed

 19509.

S1 gene analysis in Porcine epidemic diarrhea virus non S-INDEL strains in seven regions of China (Mus musculus) PubMed

 19510.

BASS2 enhances salinity tolerance of plants via modulating ABI4 expression.[BASS2, ABI4] (Mus musculus) PubMed

 19511.

Deletion of MXAN3487 significantly delayed fruiting body formation and the production of McuA, a spore coat protein secreted by the Myxococcus xanthus Mcu chaperone-usher system.[MXAN3487] (Mus musculus) PubMed

 19512.

HTLV-1 HBZ Protein is instead exclusively localized in the cytoplasm of peripheral blood mononuclear cells (PBMC) from patients suffering of Myelopathy/Tropical Spastic Paraparesis. [HBZ] (Mus musculus) PubMed

 19513.

YhaV cleaves ompF and lpp mRNAs in a translation-dependent manner [YhaV] (Mus musculus) PubMed

 19514.

Data suggest MIP_05962 exhibits molecular chaperone activity in refolding of E coli proteins MalZ and CS/gltA, preventing protein aggregation, promoting enzyme stability, and restoring enzyme activity (21% for MalZ, 16% for CS). (MIP_05962 = heat shock protein 20, Mycobacterium indicus pranii; MalZ = maltodextrin glucosidase; CS/gltA = citrate (Si)-synthase) [MalZ, maltodextrin glucosidase; CS/gltA, citrate (Si)-synthase] (Mus musculus) PubMed

 19515.

fine mapping and candidate gene analysis - [ts1] (Mus musculus) PubMed

 19516.

Structural comparisons among the three different forms of B. halodurans FadR revealed that the movement of DNA binding domains toward the operator DNA was blocked upon binding of ligand molecules (FadR). (Mus musculus) PubMed

 19517.

Gal-GalNAc, which is overexpressed in colorectal adenocarcinoma, is recognized by fusobacterial Fap2, which functions as a Gal-GalNAc lectin.[Fap2] (Mus musculus) PubMed

 19518.

Expression, purification, and characterization of a novel acidic Lipoxygenase (LOX) from Myxococcus xanthus has been reported. [LOX] (Mus musculus) PubMed

 19519.

This study demonstrates that hepatitis C virus NS4B protein induces epithelial to mesenchymal transition progression via the upregulation of Snail in hepatocellular carcinoma, which may be a novel underlying mechanism for hepatitis C virus-associated hepatocellular carcinoma development, invasion and metastasis.[NS4B] (Mus musculus) PubMed

 19520.

mirn23a regulates a complex array of transcription and signaling pathways to modulate adult hematopoiesis [miRN23a, mouse] (Mus musculus) PubMed

 19521.

OsCNGC13 acts as a novel maternal sporophytic factor required for stylar [Ca2+]cyt accumulation, extracellular matrix components modification and style transmission tract cell death, thus facilitating the penetration of pollen tube in the style for successful double fertilization and seed-setting in rice. [OsCNGC13] (Mus musculus) PubMed

 19522.

Together, these results establish that the PfRh5/PfRipr/CyRPA complex is essential in the sequential molecular events leading to parasite invasion of human erythrocytes.[PfRh5, PfRipr, CyRPA] (Mus musculus) PubMed

 19523.

The global analysis of CovR-D53E mutant indicates dimerization-dependent and dimerization-independent modes of CovR-mediated repression, thereby establishing distinct mechanisms by which this critical regulator coordinates virulence gene expression.[CovR] (Mus musculus) PubMed

 19524.

Mechanistically, Yersinia pseudotuberculosis YopM recruits and activates the mouse host kinases PRK1 and PRK2 to negatively regulate pyrin by phosphorylation.[YopM] (Mus musculus) PubMed

 19525.

The full-length 5 UTR of the zorO type I toxin hinders its own translation independent of the sRNA whereas a processed 5 UTR promotes translation (ZorO). (Mus musculus) PubMed

 19526.

we determined the X-ray crystal structure of the PLP-bound form of S1PL2021 at 2.1 A resolution revealing that the enzyme displays a conserved structural fold and active site architecture comparable with known S1PLs. The combined data suggest that B. pseudomallei has the potential to degrade host SLs in a S1PL-dependent manner. (Mus musculus) PubMed

 19527.

Phosphate uptake experiments indicated that PhoU significantly decreased the PstSCAB transport rate specifically in phosphate-replete cells but not in phosphate-starved cells and that PhoU could rapidly respond to elevated environmental phosphate concentrations and decrease the PstSCAB transport rate.[PhoU, PstSCAB] (Mus musculus) PubMed

 19528.

The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein (eap) binding to C4b has been presented. [eap] (Mus musculus) PubMed

 19529.

Data suggest that Vibrio splendidus 13B01 exhibits alginate lyases PL7A, PL7B, PL7E, PL7F, and PL7G that are secreted and are responsible for rapid digestion of extracellular alginate. [PL7A, alginate lyase PL7A; PL7B, alginate lyase PL7B; PL7E, alginate lyase PL7E; PL7F, alginate lyase PL7F; PL7G, alginate lyase PL7G] (Mus musculus) PubMed

 19530.

Data suggest that, although Cry6Aa1 forms pores in planar lipid bilayers, the molecular determinants of its mode of action are significantly different from those reported for other B. thuringiensis nematocidal/insecticidal toxins; Cry6Aa1 forms pores at very low doses and in a wide range of pH; Cry6Aa1 does not need proteolytic processing to form pores. [Cry6Aa1, insecticidal crystal protein Cry6Aa1] (Mus musculus) PubMed

 19531.

Data suggest that CHO1 expression in PAH1-deletion mutant cells is induced via inositol-sensitive upstream activation sequence/response element involving phosphatidate controlled Henry (INO2-INO4/OPI1) regulatory circuit. [CHO1, CDP-diacylglycerol-serine O-phosphatidyltransferase 1; PAH1, phosphatidate phosphatase PAH1; INO2, transcription factor INO2; INO4, transcription factor INO4; OPI1, transcriptional regulator OPI1] (Mus musculus) PubMed

 19532.

cFTR1 is an iron permease and involved in the iron reduction/re-oxidation uptake. [cFTR1] (Mus musculus) PubMed

 19533.

Data suggest that polysaccharide utilization loci 1/2 (PUL1 and PUL2) are translated into polysaccharide lyase isoenzymes (BT0263, BT3687) with substrate specificity that includes complex arabinogalactan proteins; phylogeny studies suggest tyrosine in active site participates in beta-elimination reaction. [BT_0263, polysaccharide lyase BT0263; BT_3687, polysaccharide lyase BT3687.] (Mus musculus) PubMed

 19534.

Loss of function of ERMES (endoplasmic reticulum- mitochondria encounter structure) induces iron deficiency response in yeast; a dominant mutation in VPS13 partially suppresses this iron deficiency response and iron accumulation; deletion of SAM37 impairs mitochondrial protein import in manner similar to VPS13 mutants. [VPS13 = membrane morphogenesis protein VPS13; SAM37 = SAM complex subunit SAM37] (Mus musculus) PubMed

 19535.

ImuC was critical for the survival of bacteria with impaired base excision repair (BER) functions upon alkylation damage, lacking DNA glycosylases AlkA and/or Tag. A shift in growth temperature from 30 degrees C to 37 degrees C resulted in the disappearance of ImuC-dependent MMS tolerance- and mutator phenotypes. ImuC. (Mus musculus) PubMed

 19536.

The authors delineated the fungal ligands to be the Candida glabrata adhesins Epa1, Epa6, and Epa7 and demonstrated that clearance of systemic Candida glabrata infections in vivo depends on their recognition by mouse NCR1.[Epa1, Epa6, and Epa7] (Mus musculus) PubMed

 19537.

RctB consists of four domains and the structure of its central two domains resembles that of several plasmid replication initiators (RctB). (Mus musculus) PubMed

 19538.

Characterization of the TaSnRK2.10 gene and its association with agronomic traits in wheat. [TaSnRK2] (Mus musculus) PubMed

 19539.

Crystal structure of a bicupin protein HutD involved in histidine utilization in Pseudomonas fluorescens has been reported. [HutD] (Mus musculus) PubMed

 19540.

Here the authors identify Stk2, a staphylococcal serine/threonine kinase that provides efficient immunity against bacteriophages by inducing abortive infection.[Stk2] (Mus musculus) PubMed

 19541.

Thus, Streptococcus pneumoniae senses and responds to sialic acid N-acetylneuraminic acid (Neu5Ac), leading to CiaR activation and increased virulence and potentially explaining the greater susceptibility in humans. (Mus musculus) PubMed

 19542.

Signal perception by the sensor domains of BvgS triggers small motions of the helical linker region underneath. The protein domain that follows this linker undergoes a large conformational change that amplifies the initial signal, causing a shift of activity from kinase to phosphatase.[BvgS] (Mus musculus) PubMed

 19543.

S225 phosphorylation regulates the interactions of NS5A with a defined subset of cellular proteins. Furthermore, these interactions regulate both HCV genome replication and the subcellular localization of replication complexes. [NS5A] (Mus musculus) PubMed

 19544.

Infection with RRV led to perinuclear wrapping by acetylated microtubule (MT) bundles and identified ORF52 as the viral protein underlying these changes. Incoming virions were able to supply sufficient ORF52 to induce MT thickening and acetylation near the MT-organizing center, potentially aiding in the delivery of viral genomes to the nucleus. (Mus musculus) PubMed

 19545.

Structural and biochemical studies on Vibrio cholerae Hsp31 reveal a novel dimeric form and glutathione-independent glyoxalase activity. [Hsp31] (Mus musculus) PubMed

 19546.

MYB31, is a R2R3 type MYB transcription factor acting as a negative regulator of lignin biosynthesis in banana. [MYB31] (Mus musculus) PubMed

 19547.

Upon sensing high concentrations of glutamate, GluR-GluK would be activated and thereby facilitate glutamate uptake by increasing gluABCD expression.[GluR, GluK] (Mus musculus) PubMed

 19548.

Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei has been described. [IDH1] (Mus musculus) PubMed

 19549.

Functional characterization of 3-ketosteroid 9alpha-hydroxylases (KshAB) in Rhodococcus ruber strain chol-4 has been described. [KshA], [KshB] (Mus musculus) PubMed

 19550.

This secreted effector, toxoplasma inhibitor of STAT1-dependent transcription (TgIST), translocates to the host cell nucleus, where it recruits mouse Mi-2/NuRD to STAT1-dependent promoters, resulting in altered chromatin and blocked transcription.[TgIST] (Mus musculus) PubMed

 19551.

both Ppr10 and Mpa1 play a role in synthesis of mtDNA-encoded proteins and that impaired mitochondrial protein synthesis caused by ppr10 or mpa1 deletion results in respiratory defects (Ppr10 and Mpa1). (Mus musculus) PubMed

 19552.

This work reveals a new function for the VxrA-VxrB two-component signal transduction as a regulator of biofilm formation and suggests that this regulation may act through key biofilm regulators and the modulation of cellular c-di-GMP levels.[VxrA, VxrB] (Mus musculus) PubMed

 19553.

Data suggest that Ezh2 (histone-lysine N-methyltransferase) apoenzyme exhibits an autoinhibited state; binding of cofactor S-adenosylmethionine mitigates this autoinhibited structural state allowing methylation of histone H3 lysine 27. [Ezh2, histone-lysine N-methyltransferase Ezh2] (Mus musculus) PubMed

 19554.

Data suggest that covalent flavinylation of FrdA is autocatalytic; active site side chains may impact the covalent flavinylation chemistry directly. [FrdA, anaerobic fumarate reductase catalytic and NAD/flavoprotein subunit] (Mus musculus) PubMed

 19555.

Data suggest mftC catalyzes formation of 2 isomeric products: mftA* is tyramine-Val-crosslinked peptide formed by mftC via 2 S-adenosylmethionine-dependent turnovers; substitution of penultimate mftA Val29 (and presence of mftB) causes accumulation of mftA** minor product containing alpha/beta-unsaturated bond. [mftC, mycofactocin radical SAM maturase; mftA, mycofactocin precursor; mftB, mycofactocin system protein mftB] (Mus musculus) PubMed

 19556.

Data suggest that CcmG can efficiently reduce disulfide bond of apocytochrome c and also resolve a mixed disulfide bond formed between apocytochrome c and CcmH; during cytochrome c maturation, CcmG appears to confer efficiency and CcmH appears to ensure stereo-specificity. [CyC, cytochrome c; CcmG, cytochrome c maturation component G; CcmH, cytochrome c maturation component H] (Mus musculus) PubMed

 19557.

Genomic analysis reveals an ancient, nine-exon deletion in the ferret CMAH gene that is shared by the Pinnipedia and Mustelidae members of the Carnivora. Cytidine monophosphate-N-acetylneuraminic acid hydroxylase [CMAH] (Mus musculus) PubMed

 19558.

These results argue that the release of oocyte meiotic arrest in Xenopus is independent of a reduction in either cAMP levels or PKA activity, but rather proceeds through a parallel cAMP/PKA-independent pathway.[Protein kinase A] (Mus musculus) PubMed

 19559.

identified promoters that are CtrA targets and found CtrA binds to promoters of genes involved in cell cycle progression; also found CtrA depletion affected outer membrane composition, in particular abundance and spatial distribution of Omp25; control of B. abortus envelope composition by CtrA indicates the plasticity of the CtrA regulon along evolution [CtrA] (Mus musculus) PubMed

 19560.

identification, characterization and mutagenesis of the gene encoding the choline phosphotransferase activity that completes the CDP-choline-dependent phosphatidylcholine biosynthesis pathway in Treponema spp [1,2-diacylglycerol choline phosphotransferase] (Mus musculus) PubMed

 19561.

The Plasmodium falciparum malarial parasite genome appears to encode one and only one phosphatidylinositol 3'-kinase (PI3K), and sequence analysis suggests that the enzyme is a "class III"- or "Vps34"-type PI3K. PfVps34 has generated excitement as a possible druggable target and potentially a key target of artemisinin-based antimalarials. (Mus musculus) PubMed

 19562.

These findings indicate that kinetoplast polyadenylation factor 3 (KPAF3) selectively directs pre-mRNA toward adenylation rather than uridylation, which is a default post-trimming modification characteristic of ribosomal and guide RNAs.[KPAF3] (Mus musculus) PubMed

 19563.

HevABCC2 is the central target in Cry1A toxin mode of action, and HevCaLP plays a supporting role in increasing Cry1A toxicity.[ABCC2,CaLP] (Mus musculus) PubMed

 19564.

Overall, the pleiotropic defects of the acyA deletion mutant indicates that the cAMP-protein kinase A pathway is involved in fungal development, aflatoxins biosynthesis and plant seed invasion in Aaspergillus flavus. (Mus musculus) PubMed

 19565.

Active Sites of O2-Evolving Chlorite Dismutases Probed by Halides and Hydroxides and New Iron-Ligand Vibrational Correlations (Mus musculus) PubMed

 19566.

Compared to the wild-type, the mutants DeltamsrA and DeltamsrAB displayed significantly reduced resistance to predation by Tetrahymena thermophila, and 50% lethal dose (LD50) determinations in zebrafish demonstrated that both mutants were highly attenuated.[mrA, msrB] (Mus musculus) PubMed

 19567.

These findings suggest conserved roles for Six3/6 and Frizzled5/8 in aboral/anterior development and reveal key functions for Nvbeta-catenin in the patterning of the entire oral-aboral axis of Nematostella.[beta catenin, Six3, Six6, Frizzled5, Frizzled 8] (Mus musculus) PubMed

 19568.

These data argue that Aspartate 836 can partially substitute for activation loop phosphorylation in activation of the endoribonuclease domain of Ire1.[Ire1] (Mus musculus) PubMed

 19569.

This study is the first to show the essential role of the KupA protein for resistance to sucrose-induced stress in bacteria by acting as a high-affinity potassium transporter in Gluconacetobacter diazotrophicus PAl 5.[KupA] (Mus musculus) PubMed

 19570.

the formation of a complex between AgamOBP1 and Icaridin, an efficient DEET alternative, is reported.[OBP1] (Mus musculus) PubMed

 19571.

Triggers targeting RPS6 and RPL26 effectively reduced gene expression but more importantly, reduced reproductive output by more than 96% and 91% at the first oviposition.[RPS6,RPL26] (Mus musculus) PubMed

 19572.

Pil3 pilus binds equally well to human colonic mucins. [Pil3] (Mus musculus) PubMed

 19573.

Ccp1 interacts with CENP-A and is recruited to centromeres at the end of mitosis in a Mis16-dependent manner. [Ccp1] (Mus musculus) PubMed

 19574.

double electron-electron resonance measurements of intermolecular distances in the Pdx/P450cam complex show that the geometry of the complex is nearly identical for the open and closed states of P450cam. These studies show that Pdx appears to make a single distinct interaction with its binding site on the enzyme and triggers the conformational change through very subtle structural interactions. (Mus musculus) PubMed

 19575.

Repeated rounds of swarming by wildtype Pf-5 drives the accumulation of gacS/gacA spontaneous mutants on the swarming edge. [gacA, gacS] (Mus musculus) PubMed

 19576.

The structure of thymidylate kinase from Candida albicans, determined by X-ray crystallography, is reported to a resolution of 2.45 A with a final Rfree of 0.223. Thymidylate kinase from C. albicans possesses a unique 15-residue loop that is not seen in thymidylate kinases from other genera. (Mus musculus) PubMed

 19577.

Results demonstrated that the SrbA is important for biofilm growth in pseudomona aeruginosa and its pathogenicity. [SrbA ] (Mus musculus) PubMed

 19578.

Functionality assays revealed that AutB synthesis promotes biofilm formation and delays the passage of epithelial cell layers in vitro.[AutB] (Mus musculus) PubMed

 19579.

Furthermore, the authors have revealed that the fourth amino acid in the N-terminal direction from cleavage site of PPKTG forms specific interaction with Clostridium difficile-SrtB and plays an essential role in configuring the peptide to allow more efficient substrate-specific cleavage by Clostridium difficile-SrtB.[SrtB] (Mus musculus) PubMed

 19580.

The PacC deletion mutant showed a reduced ability to acidify media during growth due to failure to produce oxalic acid. [PacC] (Mus musculus) PubMed

 19581.

investigated the roles of EbpA, TcrA, TcsA and RpoN in the expression of lpiA and present a regulatory model which could explain how the lpiA/acvB operon is acid activated [sigma factor RpoN, IpiA] (Mus musculus) PubMed

 19582.

Using strand-specific RNA-sequence analysis, study identified differentially expressed chromosomal and plasmid-encoded genes, antisense transcripts, and transcripts within intergenic regions that are controlled by the VirR or RevR regulatory systems. [VirR and RevR] (Mus musculus) PubMed

 19583.

The vaccinia virus K7 protein promotes histone methylation associated with heterochromatin formation [K7 protein] (Mus musculus) PubMed

 19584.

Results of quantitive-PCR showed that, in the process of infection in apple fruit, gene expressions of polygalacturonase genes pgaI, pgaII, pgaA, pgaC, pgaD and pgaE were enhanced in DeltapgxB mutant in comparison to wild type. (Mus musculus) PubMed

 19585.

The UAG-dependent translation termination was more dependent on PrmC activity than the UAA- and UGA-dependent translation termination. [PrmC] (Mus musculus) PubMed

 19586.

results demonstrated that GlnR regulated acetyl-CoA synthetases at transcriptional and post-translational levels, and mediated the interplay between nitrogen and carbon metabolisms by integrating nitrogen signals to modulate the acetate metabolism [GlnR]. (Mus musculus) PubMed

 19587.

Identification of TgNup302-interacting proteins also provides the first glimpse at the nuclear pore complex structure in Apicomplexa.[Nup302] (Mus musculus) PubMed

 19588.

the membrane PAP2 coded by the Bacillus subtilis yodM gene is the principal phosphatidylglycerol phosphate (PGP) phosphatase of B. subtilis.[PAP2] (Mus musculus) PubMed

 19589.

glycosylated and nonglycosylated models displayed distinct patterns that could influence their catalytic activity [m1] (Mus musculus) PubMed

 19590.

much lower alpha-glucosidase activity compared to Aedes aegypti enzyme [m1] (Mus musculus) PubMed

 19591.

CagA is required for increased expression of beta-catenin and its target CIC markers via downregulation of microRNA (miR)-320a and miR-4496. [CagA protein, Helicobacter pylori NCTC11637] (Mus musculus) PubMed

 19592.

results indicate that DnaA modulates the activity of Rok; postulate that this interaction might affect nucleoid architecture; DnaA might interact similarly with Rok analogues in other organisms [DnaA, Rok] (Mus musculus) PubMed

 19593.

Mechanistically, West Nile virus NS1 targets RIG-I and melanoma differentiation-associated gene 5 (MDA5) by interacting with them and subsequently causing their degradation by the proteasome.[NS1] (Mus musculus) PubMed

 19594.

Crystal structure of LysK, an enzyme catalyzing the last step of lysine biosynthesis in Thermus thermophilus, in complex with lysine provides insight into the mechanism for recognition of the amino-group carrier protein, LysW. [LysK],[LysW] (Mus musculus) PubMed

 19595.

This study analyzed the binding of the liver-specific microRNA-122 (miR-122) to three conserved target sites of hepatitis C virus (HCV) RNA, two in the non-structural protein 5B (NS5B) coding region and one in the 3' untranslated region (3'UTR). [non-structural protein 5B ] (Mus musculus) PubMed

 19596.

Results indicate that OsMTP11 is a Mn-transport protein that drives the metal efflux to the yeast extracellular compartment, and might also be an important Mn transporter in rice. Expression pattern analysis indicated that OsMTP11 was induced by heavy metals and the promoter region of OsMTP11 contains several metal response elements, which might play vital roles in regulating metal inducible expression pattern. [OsMTP11] (Mus musculus) PubMed

 19597.

The functional characterization of two tyramine receptors from the honeybee, AmTAR1 (previously named AmTYR1) and AmTAR2, which respond to tyramine by changing cAMP levels in opposite direction, is an important step towards understanding the actions of tyramine in honeybee behavior and physiology, particularly in comparison to the effects of octopamine.[Tyr2] (Mus musculus) PubMed

 19598.

Here the authors confirm the function of GcbA in Pseudomonas putida and reveal that expression of GcbA is regulated by FleQ in response to c-di-GMP.[GcbA] (Mus musculus) PubMed

 19599.

evidence is provided that in polysaccharide intercellular adhesin-negative S. epidermidis 1457Deltaica, the metalloprotease SepA is required for Aap-dependent S. epidermidis biofilm formation in static and dynamic biofilm models [SepA] (Mus musculus) PubMed

 19600.

This study provides both novel and significant findings that establish a role for LcrV in early targeting of YopH effector in the host cell.[LcrV, YopH] (Mus musculus) PubMed

 19601.

Ku: Mm-Ku (from Mycobacterium marinum) with the Mt-LigD (from Mycobacterium tuberculosis), or the Mt-Ku with the Mm-LigD can function together to join DNA double strand breaks in E. coli. NHEJ repair is therefore conserved between the two species. (Mus musculus) PubMed

 19602.

ligD: Mm-Ku (from Mycobacterium marinum) with the Mt-LigD (from Mycobacterium tuberculosis), or the Mt-Ku with the Mm-LigD can function together to join DNA double strand breaks in E. coli. NHEJ repair is therefore conserved between the two species. (Mus musculus) PubMed

 19603.

TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway [HPO] (Mus musculus) PubMed

 19604.

The authors show here that the alveolin IMC1c is palmitoylated on a conserved cysteine motif, and that non-palmitoylated IMC1c displays normal expression, stability and trafficking.[IMC1c] (Mus musculus) PubMed

 19605.

larval expression of ancient V2Rs is gradually lost from the main olfactory epithelium as it transforms into the air nose.[V1R, V2R] (Mus musculus) PubMed

 19606.

DNA repair profiles of 223 sites in the human genome demonstrate that the pattern of DNA repair following Cas9 cutting at each site is nonrandom and consistent. (Mus musculus) PubMed

 19607.

The analysis demonstrated that N co-localizes and interacts with both glycoproteins Gn and Gc, with a preference for Gn.[Gn & Gc] (Mus musculus) PubMed

 19608.

Dact1 and Dact2, which are expressed in pre-migratory neural crest (NC) cells, are required for NC delamination in Xenopus and chick embryos.[DACT2] (Mus musculus) PubMed

 19609.

Edc1 makes additional contacts with the regulatory domain of Dcp2 and the activation motif in Edc1 increases the RNA affinity of Dcp1:Dcp2. (Mus musculus) PubMed

 19610.

Thermus thermophilus Ago can independently generate and selectively load functional DNA guides to mediate host defense by targeting invading DNA complementary to the DNA guide. (Mus musculus) PubMed

 19611.

These findings demonstrate an essential role for the ERK pathway together with c-JUN and c-FOS in the differentiation activity of LukS-PV. (Mus musculus) PubMed

 19612.

Data suggest that the KtrAB K+ transport system (ktrA and ktrB) plays a central role in C. jejuni physiology and pathological colonization of mouse intestine. [ktrA, potassium uptake protein ktrA; ktrB, potassium uptake protein ktrB] (Mus musculus) PubMed

 19613.

Data suggest that Red1 forms stable complex with Hop1 in vitro; Red1 preferentially associates with Holliday junction and 3-way junction rather than with single- or double-stranded DNA with overhangs; Red1, by itself, lacks DNA-pairing ability; Red1 potentiates Hop1-promoted intermolecular pairing between double-stranded DNA molecules. [Red1, synaptonemal complex component Red1; Hop1, synaptonemal complex component Hop1] (Mus musculus) PubMed

 19614.

Rpb1/2 dynamics help govern the decision between sense and divergent antisense transcription. (Mus musculus) PubMed

 19615.

Data suggest that two of the four disulfide bonds of pIII of CTX phage are required for its interaction with TolA of Vibrio cholerae O395; two intermolecular salt bridges (one involves Arg-325 of TolA) between TolA and pIII provide the driving forces of the complex interaction. (TolA = TolA protein; pIII, minor coat protein) [TolA, TolA protein] (Mus musculus) PubMed

 19616.

NicA2 is a flavin-containing protein, which degrades nicotine. [NicA2] (Mus musculus) PubMed

 19617.

muscle proteins as novel targets of irisin [irisin] (Mus musculus) PubMed

 19618.

We demonstrate that miR-275 directly targets and positively regulates sarco/endoplasmic reticulum Ca2+ adenosine triphosphatase, which is implicated in active transport of Ca2+ from the cytosol to the sarco/endoplasmic reticulum. [MicroRNA-275] (Mus musculus) PubMed

 19619.

Cells lacking Twi8p arrest in sexual reproduction with zygotic nuclei that retain the germline genome structure, without the DNA elimination and fragmentation required to generate a functional macronucleus. [Twi8p] (Mus musculus) PubMed

 19620.

This study revealed the critical role of the conserved tryptophan residues in Fc-binding protein PiaA, and provided valuable information for understanding the Fc transport mechanism mediated by PiaA or its homologous proteins in bacteria. (Mus musculus) PubMed

 19621.

We also show that a mutant disrupted in egtA, coding for a gamma-glutamyl cysteine synthetase and lacking in ergothioneine, is sensitive to nitrosative stress but not to aldehydes. In addition, we find that MSH and S-nitrosomycothiol reductase are required for normal biofilm formation in M. smegmatis, suggesting potential new therapeutic pathways to target to inhibit or disrupt biofilm formation. (Mus musculus) PubMed

 19622.

In the absence of polyglutamine, MOAG-2/LIR-3 regulates the RNA polymerase III-associated transcription of small non-coding RNAs. Polyglutamine can induce an aggregation-promoting activity of MOAG-2/LIR-3 in the cytosol. (Mus musculus) PubMed

 19623.

Report the crystal structures of Campylobacter jejuni Cas9 (CjCas9), one of the smallest Cas9 orthologs, in complex with a guide RNA and its target DNA. (Mus musculus) PubMed

 19624.

molecular cloning and expression analysis suggest a role in spermatogenesis - [aqp1aa] (Mus musculus) PubMed

 19625.

Conversion of OprO into an OprP-like Channel by Exchanging Key Residues in the Channel Constriction [OprO][OprP] (Mus musculus) PubMed

 19626.

Biocatalytic pulp fibers were prepared using surface functionalization of bleached kraft pulp with amino groups (F) and further immobilization of a cross-linked glucose oxidase (G*) from Aspergillus niger.Using the approach described on this paper, several advanced materials from wood pulp fibers and new bioprocesses might be developed by selecting the correct enzyme for the target applications (Mus musculus) PubMed

 19627.

expression of lhp genes for hydroxy-l-proline catabolism and uptake requires the transcriptional activator LhpR and hydroxy-l-proline as the signalling compound. [LhpR] (Mus musculus) PubMed

 19628.

these findings identify ASAP2 as a new target of Selk-dependent palmitoylation and reveal a new mechanism regulating the efficiency of FcgammaR-mediated phagocytosis.[FcgammaR] (Mus musculus) PubMed

 19629.

The results demonstrate that VLN2 plays an important role in regulating plant architecture by modulating MF dynamics, recycling of PIN2, and polar auxin transport (VLN2). (Mus musculus) PubMed

 19630.

The data suggest that Kif15 recruits Escherichia coli EspW to the site of bacterial attachment, which in turn activates Rac1, resulting in modifications of the actin cytoskeleton that are essential to maintain cell shape during infection.[EspW] (Mus musculus) PubMed

 19631.

These results suggested that Streptococcus pneuomoniae PLY induces the influx of calcium in Streptococcus pneumoniae-infected macrophages, followed by calpain activation and subsequent IL-1alpha maturation and secretion. (Mus musculus) PubMed

 19632.

A functional HECT E3 ligase domain with a conserved catalytic site was identified in the C-terminal region of TRP120, and TRP120 autoubiquitination occurred in vitro in the presence of host UbcH5b/c E2 enzymes.[TRP120] (Mus musculus) PubMed

 19633.

These results demonstrate that EsaB/EsaL/EsaM form a ternary complex controlling the secretion of type III secretion system translocon and effector proteins and contributing to Edwardsiella tarda pathogenesis.[EsaB, EsaL, EsaM] (Mus musculus) PubMed

 19634.

A function of Pdc2-Lsm1, in concert with Dhp1, regulating RNA by promoting its decapping/destruction in the nucleus of Schizosaccharomyces pombe was suggested. [Pdc2] (Mus musculus) PubMed

 19635.

CagLHM regional diversity may contribute to the varied prevalence of Helicobacter pylori-related gastric cancer observed in diverse populations. (Mus musculus) PubMed

 19636.

Data indicate that cytolethal distending toxin (CDT) may be involved in chronic inflammatory responses, via its active subunit, CdtB (CdtB). (Mus musculus) PubMed

 19637.

miR-146a-5p targets porcine insulin receptor and could inhibit its protein expression. [miR-146a-5p] (Mus musculus) PubMed

 19638.

Electrostatic Interactions at the Dimer Interface Stabilize the E. coli beta Sliding Clamp [beta clamp] (Mus musculus) PubMed

 19639.

Inhibition of homologous PNPase by citrate may represent an evolutionarily conserved communicative link between RNA degradation and central metabolism. [polynucleotide phosphorylase] (Mus musculus) PubMed

 19640.

MiR-2 approximately 13 approximately 71 cluster played important roles in deltamethrin resistance through regulating target genes, CYP9J35 and CYP325BG3 [CYP9J35, CYP325BG3] (Mus musculus) PubMed

 19641.

Circular RNA circ-ZNF609 is associated with heavy polysomes, and it is translated into a protein in a splicing-dependent and cap-independent manner, resulting in a protein that controls myoblast proliferation. (Mus musculus) PubMed

 19642.

Using genetic methods and mass spectrometry, the authors demonstrate that LpxL1 catalyzes the addition of laureate and LpxL2 catalyzes the addition of myristate to lipid A.[LpxL1, LpxL2] (Mus musculus) PubMed

 19643.

The ability of Clostridium perfringens to regulate its exosialidase activity, largely by controlling nanI expression via NanR, may affect intestinal pathogenesis by affecting the production of NanI, which may affect Clostridium perfringens growth, adhesion, and toxin binding in vivo.[NanI, NanR] (Mus musculus) PubMed

 19644.

These data indicate that an intact MisRS system is required for gonococcal infection of mice.[MisR, MisS] (Mus musculus) PubMed

 19645.

These results demonstrate that inactivation of the pdcA gene is sufficient to impact multiple c-di-GMP-dependent phenotypes, including the production of major virulence factors, and suggest a link between c-di-GMP signaling and nutrient availability. (Mus musculus) PubMed

 19646.

Data suggest Ime4 regulates triglyceride synthesis and vacuolar morphology/size through its target Faa1 gene; additionally Aft2 up-regulates FAA1 expression. (Ime4 = mRNA (N6-adenosine)-methyltransferase; Faa1 = long-chain fatty acid-CoA ligase FAA1; Aft2 = activating transcription factor 2) [Ime4, mRNA (N6-adenosine)-methyltransferase; Faa1, long-chain fatty acid-CoA ligase FAA1; Aft2, activating transcription factor 2] (Mus musculus) PubMed

 19647.

Human and Plasmodium serine hydroxymethyltransferases differ in rate-limiting steps and pH-dependent substrate inhibition behavior (Mus musculus) PubMed

 19648.

7b localizes to and is retained in the medial- and/or trans-Golgi compartment. [7b] (Mus musculus) PubMed

 19649.

NS1 is released from mosquito cells via an unconventional secretory route that bypasses the Golgi complex, with the participation of CAV1. (Mus musculus) PubMed

 19650.

MYB2 functions as part of a multidimensional regulatory network to define the temporal and spatial pattern of anthocyanin and PA accumulation linked to developmental processes. [MYB2] (Mus musculus) PubMed

 19651.

Salmonella typhimurium SteD caused MARCH8-dependent ubiquitination and depletion of surface-localized mature MHC class II antigens.[SteD] (Mus musculus) PubMed

 19652.

Report the structural basis for guide RNA processing and seed-dependent DNA targeting by CRISPR-Cas12a (Francisella novicida) system. (Mus musculus) PubMed

 19653.

The Salmonella adaptor ClpS binds to the N terminus of the regulatory protein PhoP, resulting in PhoP degradation by ClpAP. (Mus musculus) PubMed

 19654.

the critical role of PLP synthases PdxS/PdxT in viability, stress tolerance, and virulence of A. pleuropneumoniae [PdxS][PdxT] (Mus musculus) PubMed

 19655.

HexA fulfills the task as repressor of 1 degrees specific features in 2 degrees cells in a versatile way and gives first insights into the complexity of regulating phenotypic heterogeneity in Photorhabdus bacteria [HexA] (Mus musculus) PubMed

 19656.

Results identified Blu7 which appears to regulate light sensitivity in terms of induction of conidiation, and to play a major role in supporting growth under continuous exposure to light. [Blu7] (Mus musculus) PubMed

 19657.

PenA membrane association is not required for drug resistance. [PenA] (Mus musculus) PubMed

 19658.

The sizes of Siglec-3, Siglec-5 and Siglec-10 are approximately 60 kD, 120 kD and 95 kD,, respectively.[ Siglec3] (Mus musculus) PubMed

 19659.

OmpK35 and OmpK36 role in the host inflammatory response to outer membrane vesicles of Klebsiella pneumonia. [OmpK35] [OmpK36] (Mus musculus) PubMed

 19660.

FosA3, blaKPC-2, blaCTX-M-65, blaSHV-12, and rmtB proteins in the fosfomycin resistant epidemic Klebsiella pneumoniae strain isolated in China.[fosA3] [blaKPC-2] [ blaCTX-M-65] [blaSHV-12] [ rmtB] (Mus musculus) PubMed

 19661.

We identified 3 Siglec-like genes, (OnSiglec-1-like/-4b-like/-14-like). All the genes had specific domains (immunostimulation and immunosuppression domains), conserved amino acid residues, and sialic acid polysaccharide binding sites that are found in mammalian Siglecs. (Mus musculus) PubMed

 19662.

YjjPB constitutes a succinate transporter in E. coli [YjjP][YjjB] (Mus musculus) PubMed

 19663.

Data, including metabolomics data on S. pombe lacking Loz1, suggest gluconate shunt is alternative to pentose phosphate pathway; Gcd1 functions in pathway with Idn1; cells lacking both Gcd1 and Zwf1 have more severe growth phenotype than cells lacking Zwf1 alone. [Loz1, zinc-responsive transcriptional repressor; Gcd1, NADP+-dependent glucose dehydrogenase; Idn1, gluconate kinase; Zwf1, glucose-6-phosphate dehydrogenase] (Mus musculus) PubMed

 19664.

These data suggest that calcium ion-regulated AtlA maturation mediates the release of extracellular DNA by Streptococcus mutans, which contributes to biofilm formation in infective endocarditis.[AtlA] (Mus musculus) PubMed

 19665.

The primary effect on conjugation is occlusion of the conjugative pilus by phage particles and this interaction is mediated primarily by phage coat protein g3p.[g3p] (Mus musculus) PubMed

 19666.

Colicin N and M13 phage protein G3p compete with TolB for a binding site on TolA. [G3p] (Mus musculus) PubMed

 19667.

High incidence of Escherichia coli strains coharboring mcr-1 and blaNDM from chickens has been reported in China. [mcr-1] (Mus musculus) PubMed

 19668.

Full genome sequencing identifies in the genetic background several determinants that modulate the resistance phenotype in methicillin-resistant Staphylococcus aureus strains carrying the novel mecC gene. [mecC] (Mus musculus) PubMed

 19669.

VcHigA2 binds VcHigB2 with picomolar affinity, which is mainly a consequence of entropically favorable de-solvation of a large hydrophobic binding interface and enthalpically favorable folding of the N-terminal domain into an alpha-helix followed by a beta-strand (Mus musculus) PubMed

 19670.

Similarly to Variola and Vaccinia VH1, the structure of viral tyrosine phosphatase OH1 shows a dimer with the typical dual-specificity phosphatase fold.[OH1] (Mus musculus) PubMed

 19671.

The Ybp1 operates as a scaffold protein and as a sulfenic acid chaperone to provide specificity in the transfer of oxidizing equivalents by a reactive sulfenic acid species. (YAP1 protein, S cerevisiae) (Mus musculus) PubMed

 19672.

the kinesin-13 KLP-7 promotes destabilization of the whole cellular microtubule network.[KLP-7] (Mus musculus) PubMed

 19673.

BmPrx3 belongs to the atypical 2-Cys Prxs. Recombinant BmPrx3 purified from Escherichia coli exhibited antioxidant activity that removed hydrogen peroxide and protected DNA from oxidative damage. BmPrx3 acts as an antioxidant enzyme to protect the silkworm from various oxidative stresses. (Mus musculus) PubMed

 19674.

PKA activity is essential for appressorium formation and proper activation of Pmk1 or Mps1 in M. oryzae, and phosphorylation of MoSfl1 by PKA relieves its interaction with the Cyc8-Tup1 co-repressor and suppression of genes important for hyphal growth. [PKA; MoSfl1] (Mus musculus) PubMed

 19675.

Data suggest that a short-lived anionic flavin semiquinone is not sufficient to infer existence of bifurcating activity (electron transfer between different acceptors), although such species may be necessary for process. Studies were conducted in flavodoxin from Desulfovibrio vulgaris, NADH-ferredoxin oxidoreductase from Pyrococcus furiosus, and nitroreductase from Enterobacter cloacae. [fld, flavodoxin] (Mus musculus) PubMed

 19676.

Data suggest a short-lived anionic flavin semiquinone is not sufficient to infer existence of bifurcating activity (electron transfer between different acceptors), although such species may be necessary for process. Studies were conducted in flavodoxin from Desulfovibrio vulgaris, NADH-ferredoxin oxidoreductase from Pyrococcus furiosus, and nitroreductase from Enterobacter cloacae. [nfnl, NADH-ferredoxin oxidoreductase] (Mus musculus) PubMed

 19677.

DIM-2 can mediate repeat-induced point mutation of repetitive DNA.[DIM-2] (Mus musculus) PubMed

 19678.

Data suggest that a short-lived anionic flavin semiquinone is not sufficient to infer existence of bifurcating activity (electron transfer between different acceptors), although such species may be necessary for process. Studies were conducted in flavodoxin from Desulfovibrio vulgaris, NADH-ferredoxin oxidoreductase from Pyrococcus furiosus, and nitroreductase from Enterobacter cloacae. [nr, nitroreductase] (Mus musculus) PubMed

 19679.

Two nonstructural proteins encoded by Zika virus strain MR766 RNA, a methyltransferase and a helicase, were crystallized and their structures were solved and refined at 2.10 and 2.01 A resolution, respectively. The NS5 methyltransferase contains a bound S-adenosyl-L-methionine (SAM) co-substrate. The NS3 helicase is in the apo form. [NS5 methyltransferase, NS3 helicase ] (Mus musculus) PubMed

 19680.

In the T. thioreducens Pfp1 protease structures, Cys18 residues on adjacent molecules in the asymmetric units form intermolecular disulfide bonds, thereby yielding hexamers composed of three cross-linked, quasi-dyad-related dimers with crystallographically exact threefold axes and exhibiting almost exact 32 symmetry. [Pfp1] (Mus musculus) PubMed

 19681.

coordinated activities of both Hsp104 and Hsp110 are required to reactivate aggregated proteins.[Hsp104, Hsp110] (Mus musculus) PubMed

 19682.

Complete sequence of blaOXA-163 and blaOXA-48 and their role in drug resistance [blaOXA-163] [blaOXA-48] (Mus musculus) PubMed

 19683.

Data suggest that prf exhibits two active sites that are distant and do not show evidence of direct communication; prf exhibits robust persulfide dioxygenase activity and preferentially catalyzes sulfur transfer in direction of thiosulfate to sulfite and glutathione persulfide. [prf, persulfide dioxygenase--rhodanese fusion protein] (Mus musculus) PubMed

 19684.

TCP14 regulates the plant immune system by transcriptionally repressing a subset of the jasmonic acid (JA) hormone signaling outputs. The Pseudomonas syringae type III effector, HopBB1, interacts with TCP14 and targets it to the SCF(COI1) degradation complex by connecting it to the JA signaling repressor JAZ3. HopBB1 de-represses the TCP14-regulated subset of JA response genes and promotes pathogen virulence. (Mus musculus) PubMed

 19685.

DdrC as a DNA damage response protein in Deinococcus radiodurans bacterium [DdrC] (Mus musculus) PubMed

 19686.

Haemophilus parasuis cytolethal distending toxin induces cell cycle arrest and p53-dependent apoptosis.Cytolethal distending toxin is a major virulence factor.[cytolethal distending toxin] (Mus musculus) PubMed

 19687.

testin region (amino acids 52-233) harbouring the PET domain interacts with the C-terminal LIM1-2 domains [p34] (Mus musculus) PubMed

 19688.

enetic studies revealed that YUC8/REIN7-mediated auxin biosynthesis functioned downstream of OsEIL1, which directly activated the expression of YUC8/REIN7. Thus, our findings reveal a model of interaction between ethylene and auxin in rice seedling primary root elongation, enhancing our understanding of ethylene signaling in rice. (Mus musculus) PubMed

 19689.

DNA interaction is required for some function in DNA replication initiation - [Dpb11] (Mus musculus) PubMed

 19690.

PER-8, a novel extended-spectrum beta-lactamase PER variant, from an Acinetobacter baumannii clinical isolate in Nepal has been reported. [PER-8] (Mus musculus) PubMed

 19691.

Bcin07g05490 (BcENT) was identified as sole member of the equilibrative nucleoside transporter (ENT) family.[ENT] (Mus musculus) PubMed

 19692.

transcription of the aapA1 gene generates a full-length transcript whose folding impedes translation ( a 3 end processing of this message generates a shorter transcript that, after a structural rearrangement, becomes translatable but this rearrangement also leads to the formation of two stem-loop structures allowing formation of an extended duplex with IsoA1 via kissing-loop interactions. (Mus musculus) PubMed

 19693.

Utp4 consists of two orthogonal and highly basic beta-propellers that perfectly fit the EM-data. The Utp4 structure highlights an unusual Velcro-closure of its C-terminal beta-propeller as relevant for protein integrity and potentially Utp8 recognition in the context of the pre-ribosome. UTP4. (Mus musculus) PubMed

 19694.

HRG-7, a protein with homology to aspartic proteases, mediates inter-organ signalling between the intestine and extra-intestinal tissues. Intestinal HRG-7 functions as a secreted signalling factor during haem starvation in extra-intestinal tissues . (Mus musculus) PubMed

 19695.

loss of Caspase-3 actually delayed AML1-ETO9a (AE9a)-driven leukemogenesis.[AML1-ETO] (Mus musculus) PubMed

 19696.

The Chlamydia trachomatis type III secretion substrates CT142, CT143, and CT144 are secreted into the lumen of the inclusion (Mus musculus) PubMed

 19697.

Lem10 lacks the catalytic His-Asp residue pair and does not show any in vitro phosphohydrolase enzymatic activity.[Lem10] (Mus musculus) PubMed

 19698.

Tribolium castaneum-Maelstrom promotes growth-zone formation and axis elongation.[Maelstrom] (Mus musculus) PubMed

 19699.

APOL1: The synergy of circulating factor suPAR and APOL1 G1 or G2 on alphavbeta3 integrin activation is a mechanism for CKD. (Mus musculus) PubMed

 19700.

The coexistence of qnrB62 and blaVIM-2 genes was detected in a Citrobacter freundii clinical isolate.[qnrB62] [blavim-2] (Mus musculus) PubMed

 19701.

Colistin resistance gene mcr-1 was found in E coli isolated from a pig slurry sample in Estonia. [mcr-1] (Mus musculus) PubMed

 19702.

The association of the BlaZ single nucleotide polymorphisms with drug resistance [BlaZ] (Mus musculus) PubMed

 19703.

This comparative study of the binding parameters of the bacterial H-NOXs and sGC provides a basis to guide future new structural and functional studies of each specific heme sensor with the H-NOX protein fold. (Mus musculus) PubMed

 19704.

Our results further confirm that SOX and the host exoribonuclease Xrn1 act in concert to elicit the rapid degradation of mRNA substrates observed in vivo, and that the activities of the two ribonucleases are co-ordinated. (Mus musculus) PubMed

 19705.

The blaVEB-2 gene was carried on a novel Inc-type plasmid that was likely to have originated from shrimp. [blaveb-2] (Mus musculus) PubMed

 19706.

Our data suggest that VPS-33.1 shares most of the general functions of yeast Vps33 in terms of tethering complexes in the endolysosomal system, whereas VPS-33.2 has tissue/organelle specific functions in C. elegans. (Mus musculus) PubMed

 19707.

The article reported that L. infantum ARM58 is part of a gene cluster conferring resistance to antimony at the telomeric end of chromosome 34, also comprising the neighboring genes ARM56 and HSP23. [ARM58], [ARM56], [HSP23] (Mus musculus) PubMed

 19708.

SecA domain fragments ranging in size between N643-N669 are critical for functional interactions with SecYEG-SecDF*YajC [SecA, SecD, SecF, YajC] (Mus musculus) PubMed

 19709.

SaeR/S-regulated factors decrease neutrophil-derived H2O2 and HOCl production by a mechanism independent of catalase activity. (SaeR. SaeS). (Mus musculus) PubMed

 19710.

These results implicate SET-4 as a sensory rheostat that reinforces developmental fates in response to environmental cues.[SET-4] (Mus musculus) PubMed

 19711.

Changes in the genetic composition of cagY mirrored cagT4SS function, although the mechanisms of cagY alterations differed in human isolates (mutations) versus gerbil isolates (addition/deletion of motifs). These results indicate that host carcinogenic phenotypes modify cagT4SS function via altering cagY, allowing the bacteria to persist and induce carcinogenic consequences in the gastric niche (Mus musculus) PubMed

 19712.

POU5F1 homologue from the Nile tilapia (Oreochromis niloticus), OnPou5f3, displays an expression pattern and biological activity somewhat different from those in zebrafish or medaka.[Pou5f1] (Mus musculus) PubMed

 19713.

Data suggest ComGC/cglC competence pilin exhibits molecular structure that is particularly flexible between first and second alpha-helix with first helix exhibiting slightly slower dynamics than the rest; this suggests that first helix is involved in forming pilus structure core and that parts of helices two and three are primarily surface-exposed. [cglC (also ComGC), competence protein CglC (also comG-like protein C)] (Mus musculus) PubMed

 19714.

we identify a class of genes that produces piRNAs from coding sequences in an Ago3- and Piwi5-dependent fashion. We demonstrate that the replication-dependent histone gene family is a genic source of ping-pong dependent piRNAs and that histone-derived piRNAs are dynamically expressed throughout the cell cycle, suggesting a role for the piRNA pathway in the regulation of histone gene expression (Mus musculus) PubMed

 19715.

Mcr-1 is mobilized by an ISApl1 composite transposon. Mcr-1 role in colistin resistance. [Mcr-1] (Mus musculus) PubMed

 19716.

MgrB mutations are associated with polymyxin B resistance.[MgrB] (Mus musculus) PubMed

 19717.

The heterodimeric ABC Transporter EfrCD mediates multidrug efflux in Enterococcus faecalis. [EfrCD] (Mus musculus) PubMed

 19718.

By immunohistochemistry, the localization of Neurotrophinss has been observed mainly in Purkinje cells; TrkA and TrkB-receptors in cells and fibers of granular and molecular layers. TrkC was faintly detected.[NT4] (Mus musculus) PubMed

 19719.

P7-2 functioned as a component of the SCF complex in rice, and interaction of P7-2 with GID2 implied possible roles of the gibberellic acid signaling pathway during Rice black streaked dwarf virus infection.[GID2] (Mus musculus) PubMed

 19720.

Collectively, these findings suggest that the C-terminal half of Aspergillus oryzae SO, which mediates stress-induced aggregation, is required for both septal plugging and cell fusion, whereas the N-terminal half confers an additional functionality that is essential for cell fusion.[SO] (Mus musculus) PubMed

 19721.

Multiprotein bridging factor 2 (MBF2) down-regulated the promoter activity of fibH and inhibited the effect of Bmdimmed (Bmdimm) on fibH expression. MBF2 expression was induced in silk glands after treatment with 20-hydroxyecdysone in vivo and in vitro.(Multiprotein bridging factor 2) (Mus musculus) PubMed

 19722.

Growth of this knockout mutant was impaired under high-light conditions and nitrogen deprivation, suggesting that CphA2 plays an important role in nitrogen metabolism under N2-fixing conditions.[CphA2] (Mus musculus) PubMed

 19723.

comprehensive Pol II interactomes identify the complex and functional connections between transcription machinery and other gene regulatory complexes.[RNA Pol II] (Mus musculus) PubMed

 19724.

The authors showed that GAB2 is cleaved at G238 during Coxsackievirus type B3 infection by viral proteinase 2A, generating two cleaved fragments of GAB2-N1-237 and GAB2-C238-676.[proteinase 2A] (Mus musculus) PubMed

 19725.

In this study, the demonstrate that HAPS_0217 and HAPS_1695 can functionally replace EcFadD in the Escherichia coli long-chain fatty acid-CoA ligase fadD mutant JW1794, and were thus designated fadD1 and fadD2, respectively.[fadD1, fadD2] (Mus musculus) PubMed

 19726.

The authors hypothesize that while AitP is an Fe(2+)/Co(2+) efflux transporter required for Fe(2+) homeostasis, and ultimately redox stress handling, CzcD, and YiiP export Zn(2+) to the periplasm for proper Zn(2+)-dependent signaling regulating outer membrane stability and therefore antibiotic tolerance.[AitP, YiiP] (Mus musculus) PubMed

 19727.

COMT is involved in the synthesis of both tricin and S lignin units.[COMT] (Mus musculus) PubMed

 19728.

E. coli TopA catalytic activity can be modulated by lysine acetylation-deacetylation, and prevention of TopA inactivation from excess lysine acetylation and consequent increase in negative DNA supercoiling is an important physiological function of the CobB protein deacetylase. [TopA, CobB] (Mus musculus) PubMed

 19729.

Mutation of cidB resulted in global gene expression changes, particularly in those involved with oxidative stress resistance. (Mus musculus) PubMed

 19730.

It showes that the bacterial type III effector AvrRxo1 of plant pathogens is an authentic phosphotransferase that produces two novel metabolites by phosphorylating nicotinamide/nicotinic acid adenine dinucleotide at the adenosine 3'-hydroxyl group. (AvrRxo1) (Mus musculus) PubMed

 19731.

Here, the authors show that PorX and the soluble cytoplasmic domain of PorY interact and PorX interacts with the cytoplasmic domain of PorL, a component of the Type IX secretion system membrane core complex.[PorX, PorY, PorL] (Mus musculus) PubMed

 19732.

A systematic set of mutations was introduced at the degenerate and consensus site of the multidrug efflux pump EfrCD of Enterococcus faecalis. Mutating motifs which differ among the two ATP-binding sites (Walker B, switch loop, and ABC signature) or which are involved in interdomain communication (D-loop and Q-loop) led to asymmetric results in the functional assays and were better tolerated at the degenerate site. EfrCD. (Mus musculus) PubMed

 19733.

HCV polymerase NS5B interacts with Akt/PKB. NS5B changes the cellular localization of Akt/PKB from the cytoplasm to the perinuclear region. Sequestration of Akt/PKB by NS5B could explain its exclusion from its participation in early Akt/PKB inactivation. (Mus musculus) PubMed

 19734.

Overexpression of HigB increased the expression of type III secretion system genes as well as bacterial cytotoxicity.[HigB] (Mus musculus) PubMed

 19735.

Heme binding induces SpyB dimerization, which involves disulfide bond formation between the subunits.[SpyB] (Mus musculus) PubMed

 19736.

BEL-1 crystal structure shows a conformational variability of the functionally relevant Omega-loop, which is uncommon in class A beta-lactamases. [BEL-1] (Mus musculus) PubMed

 19737.

Furthermore, the inside-out activation of GPIIb/IIIa of platelets mediated Streptococcus suis suilysin-induced platelet aggregation.[suilysin] (Mus musculus) PubMed

 19738.

The gene product of unknown function previously annotated as E. faecalis YybT is a potential cyclic dinucleotide phosphodiesterase of the GdpP family (E. faecalis GdpP). [Yybt, or GdpP] (Mus musculus) PubMed

 19739.

results suggest that Delta12-fatty acid desaturase is involved in the growth of Y. lipolytica at low temperature [FAD2] (Mus musculus) PubMed

 19740.

functional analysis of a recombinant aminopeptidase P (APP)findings indicated that APP functions at an optimal pH of 8.0, and its deletion was deleterious to the growth of T. gondii [aminopeptidase P] (Mus musculus) PubMed

 19741.

soybean produces an apoplastic glucanase inhibitor protein, GmGIP1, that binds to PsXEG1 to block its contribution to virulence. (Mus musculus) PubMed

 19742.

Results show that ZC3H32 is an mRNA-binding protein with a specific role in suppressing mRNA translation, and/or enhancing mRNA degradation in bloodstream-form trypanosomes. However, no sequence specific RNA binding was found. [ZC3H32] (Mus musculus) PubMed

 19743.

during murine emphysema, Elastin peptide-S-gal interactions contribute to a Th-1 and Th-17 proinflammatory T-cell response.[S-Gal] (Mus musculus) PubMed

 19744.

A tau-muurolol synthase from R. castenholzii was tested for thermostability and its optimum temperature was 69 degrees C and its melt temperature was 59.6 +/- 0.1 degrees C. Its k(cat)(S-1) was 0.090 +/- 0.008 and its Km(muM) was 5.9. +/- 2.0. Rcas_0622. (Mus musculus) PubMed

 19745.

We report novel regulator, STM14_1008 (named LoiA), controlling a low O2-induced signal transduction pathway for the activation of SPI-1 expression in S. Typhimurium (Mus musculus) PubMed

 19746.

KPC-3 gene associated with multidrug resistance during Klebsiella pneumoniae disease outbreak.[KPC-3] (Mus musculus) PubMed

 19747.

KPC-3 gene associated with multidrug resistance during Enterobacter cloacae disease outbreak.[KPC-3] (Mus musculus) PubMed

 19748.

Resistance to class IIa bacteriocins in E. faecium 6E6 is likely caused by the disruption of mannose phosphotransferase. [mannose phosphotransferase] (Mus musculus) PubMed

 19749.

Together, the results identify chemotaxis and sensing of oxygen by IcpB as key regulators of the Azorhizobium caulinodans-Sesbania rostrata symbiosis.[IcpB] (Mus musculus) PubMed

 19750.

There is prevalence of colistin resistance gene mcr-1 and absence of mcr-2 in Escherichia coli isolated from healthy food-producing animals in Japan. [mcr-1] (Mus musculus) PubMed

 19751.

The loop 2 region in ribosomal protein s5 confers resistance to spectinomycin and affect the fidelity of translation and ribosome biogenesis.[ribosomal protein s5] (Mus musculus) PubMed

 19752.

Mcr-1 gene associated with colistin resistance.[Mcr-1] (Mus musculus) PubMed

 19753.

Mcr-1 gene associated with colistin resistance.[Mcr-1] (Mus musculus) PubMed

 19754.

Mutations in the dihydropteroate synthase of Pneumocystis jirovecii isolates from Chilie [dihydropteroate synthase] (Mus musculus) PubMed

 19755.

An in vitro co-immunoprecipitation assay confirmed that ExsE binds to ExsC to exert negative regulatory effect on type III secretion system genes. (Mus musculus) PubMed

 19756.

Study shows the identification and functional characterization of gsc1 and kre6 genes in Pneumocystis jiroveci which are essential for the synthesis of 1,3-beta glucan and then the sensitivity to echinocandins. [gsc1, kre6] (Mus musculus) PubMed

 19757.

These results demonstrate for the first time an early and essential role for RARbeta2 in vertebrate somitogenesis.[RARbeta2] (Mus musculus) PubMed

 19758.

the selection of a nucleotide change at the miR172 binding site of Q contributed to subcompact spikes and free-threshing grains during wheat domestication.[microRNA172] (Mus musculus) PubMed

 19759.

TaWRKY33 transgenic Arabidopsis lines showed lower rates of water loss than TaWRKY1 transgenic Arabidopsis lines and wild type plants during dehydration. Most importantly, TaWRKY33 transgenic lines exhibited enhanced tolerance to heat stress. [WRKY33] (Mus musculus) PubMed

 19760.

Rrp2 possesses SUMO-binding ability and prevents excessive Top2 degradation by competing against the SUMO-targeted ubiquitin ligase (STUbL) for SUMO chain binding and by displacing SUMOylated Top2 from DNA. (Mus musculus) PubMed

 19761.

we report the replacement of the promoters of the ivoA, ivoB, and ivoC genes with the inducible promoter alcA in a single cotransformation. Co-overexpression of the three genes resulted in the production of a dark-brown pigment in hyphae. (Mus musculus) PubMed

 19762.

Data suggest an important role for transcription factor HOT1 (KY488487) in the inhibition of hyphal development by farnesoic acid: [HOT1] (Mus musculus) PubMed

 19763.

This study evaluated the mechanism by which UmuD subunits exchange via the kinetics of exchange of a number of fluorescently labeled single-cysteine UmuD variants as detected by Forster resonance energy transfer.[UmuD] (Mus musculus) PubMed

 19764.

we show that knockout cells can be discriminated by a competition-based PCR, using a mixture of three primers, among which one primer overlaps with the Cas9 cleavage site. Together, we show how to optimize primer design in order to improve the effectiveness of the discrimination. (Mus musculus) PubMed

 19765.

structure and functional analysis of Leishmania major pseudoperoxidase [pseudoperoxidase] (Mus musculus) PubMed

 19766.

Presented here are the results of O2-dependent 2-mercaptoaniline reaction using 3-mercaptopropionic acid dioxygenase isolated from Azotobacter vinelandii. Benzothiazoles are produced by the condensation of 2-mercaptoaniline with aldehydes formed by an off-pathway oxidation of primary alcohols added to aqueous reactions to solubilize the substrate. [3-mercaptopropionic acid dioxygenase] (Mus musculus) PubMed

 19767.

Study presents the crystal structure of EnvZ periplasmic sensor domain (PD) which shows similar folding topology to the PDC domains of PhoQ, DcuS, and CitA, but distinct orientations of helices and beta-hairpin structures. [EnvZ] (Mus musculus) PubMed

 19768.

Transcript levels of Psy1 in RNAi transgenic lines were decreased by 54-76 % and yellow pigment content was reduced by 26-35 % compared with controls, confirming the impact of Psy1 on carotenoid accumulation.[Psy1] (Mus musculus) PubMed

 19769.

data point to uc.417 as being an important factor in an age-dependent loss of function of brown adipose tissue[uc.417] (Mus musculus) PubMed

 19770.

In accordance with the hypothesis, DeltaoxyR/DeltakatG was distinctly more susceptible than DeltaoxyR and DeltakatG to H2O2, ONOO(-) and O2(-), moreover, it hardly grew in mouse-derived BMDM or in mice, whereas DeltakatG and DeltaoxyR grew as well as parental Frecisella tularensis LVS.[oxyR, katG] (Mus musculus) PubMed

 19771.

Additionally, the authors utilized vitroenctin-derived peptides to map the minimal Rickettsia conorii Adr1/human vitronectin interaction to the C-terminal region of vitronectin.[Adr1] (Mus musculus) PubMed

 19772.

Gcn5-mediated acetylation finely regulates Rph1 protein level and that autophagic degradation of Rph1 is important for cell homeostasis.[Gcn5, Rph1] (Mus musculus) PubMed

 19773.

These results solidify Hrq1 as a true RecQ4 homolog and position it as the premier model to determine how RecQ4 mutations lead to genomic instability and disease.[Hrq1] (Mus musculus) PubMed

 19774.

APOBEC3B-induced CAN1 mutation frequencies in yeast deficient in base excision repair endonucleases or DNA damage tolerance proteins.[APOBEC3B] (Mus musculus) PubMed

 19775.

Rgf1p/Rho1p activity positively controls a repair function that confers resistance against the anti-cancer drug Phleomycin.[Rgf1p] (Mus musculus) PubMed

 19776.

RAP1-regulated appropriate levels of long non-coding RNA TERRA and telomeric RNA:DNA hybrids are fundamental to subtelomere/telomere integrity. [RAP1] (Mus musculus) PubMed

 19777.

The results bring new insights into the extent and functionality of LuxR-type, VjvR-related transcriptional networks. [VjbR] (Mus musculus) PubMed

 19778.

data indicate that an asymmetric interaction between the NTD dimer and the CTD dimer is a common structural feature among TrmJ proteins, regardless of the presence of a substrate or a product [TrmJ] (Mus musculus) PubMed

 19779.

The structure and function of CoFeSPCd were investigated using homology structure modeling, spectroscopy, electrochemistry, steady state/pre-steady state kinetics and molecular docking. (Mus musculus) PubMed

 19780.

MFZ1 is a transcription factor that regulates the expression of KRT71 in curly fleece Chinese tan sheep. (Mus musculus) PubMed

 19781.

our results indicated that PdeH plays a major role, but has overlapping function with PdeL, in vegetative growth, development and AF biosynthesis in A. flavus. (Mus musculus) PubMed

 19782.

Here, the authors show for the first time that Bacteroides fragilis toxin (BFT )is not a freely secreted protease but is associated with outer membrane vesicles.[BFT] (Mus musculus) PubMed

 19783.

expression of EBV-encoded microRNA BART7 (ebv-miR-BART7) increases responsiveness of nasopharyngeal carcinoma to radiation treatment (Mus musculus) PubMed

 19784.

The transcriptomic comparison of Streptococcus pneumoniae D39 DeltaniaR to D39 wild-type revealed that the transcriptional regulator NiaR acts as a transcriptional repressor of niaX, pnuC, and nadC.[NiaR, niaX, pnuC, and nadC] (Mus musculus) PubMed

 19785.

the cox/cyd double mutant, but not single mutants, demonstrated a highly reduced plastoquinone pool in darkness and impaired gross oxygen evolution under light, indicating that thylakoid-based respiratory terminal oxidases are able to compensate partially for each other.[Cox, Cyd] (Mus musculus) PubMed

 19786.

NAC84 is involved in abscisic acid-induced antioxidant defense.CCaMK directly phosphorylates Ser-113 of NAC84.[NAC84] (Mus musculus) PubMed

 19787.

OXS2b and O2L1 role in cadmium tolerance.OXS2b and O2L1 interact with BOXS2-containing promoters.[OXS2b] [O2L1] (Mus musculus) PubMed

 19788.

the cloning and characterization of Leaf Tip Senescence 1 (LTS1) in rice (Oryza sativa), a recessive mutation in the gene encoding O. sativa nicotinate phosphoribosyltransferase (OsNaPRT1) in the NAD salvage pathway, is reported.[osNaPRT1] (Mus musculus) PubMed

 19789.

OsWRKY62 and OsWRKY76, two genes of the WRKY IIa subfamily, undergo constitutive and inducible alternative splicing.[WRKY62, WRKY76] (Mus musculus) PubMed

 19790.

AL1, particularly the AL1a and AL1c isoforms, plays an essential role in chloroplast development in rice.[AL1] (Mus musculus) PubMed

 19791.

these findings reveal the key roles that ERN1/ERN2 play at the very earliest stages of root nodule development.[ERN1, ERN2] (Mus musculus) PubMed

 19792.

MaERF11 may recruit MaHDA1 to its target genes and repress their expression via histone deacetylation.[MaERF11, MaHDA1, MaACO1] (Mus musculus) PubMed

 19793.

Our results indicate that the cytoplasmic Cu-Zn SOD1 affects fungal growth probably depending on detoxification of intracellular superoxide radicals, and that SOD1-mediated deoxynivalenol production contributes to the virulence of F. graminearum in wheat head infection. (Mus musculus) PubMed

 19794.

The authors found that calcineurin negatively regulates CchA on calcium uptake in response to external calcium in normally cultured cells.[calcineurin, CchA] (Mus musculus) PubMed

 19795.

CsTTG1 acts in parallel to Mict/CsGL1, a key trichome formation factor, to regulate the initiation of fruit trichomes.[Mict] (Mus musculus) PubMed

 19796.

RrgA, binds both polymeric immunoglobulin receptor (pIgR) and PECAM-1, whereas the choline binding protein PspC binds, but to a lower extent, only pIgR.[RrgA, PspC] (Mus musculus) PubMed

 19797.

Data suggest that the three enzymes, NadC, NadD, and NadE, are involved in biosynthesis of NAD+ via quinolinate-salvage pathway; NadC exhibits hexameric structure; NadD exhibits trimeric structure; NadE exhibits dimeric structure. [NadC = nicotinate-nucleotide pyrophosphorylase; NadD = nicotinate-nucleotide adenylyltransferase; NadE = NAD+ synthase] (Mus musculus) PubMed

 19798.

Review of how the polymorphisms located in the flexible C-terminal tail of CagA quantitatively influence its virulence and affect the outcome of gastrointestinal diseases (review, CagA). (Mus musculus) PubMed

 19799.

A novel ORF-17 contributes to the beta-lactamase GES-1 expression. [GES-1] (Mus musculus) PubMed

 19800.

A phage-like IncY plasmid carrying the mcr-1 gene in Escherichia coli from a pig farm in China has been characterized. [mcr-1] (Mus musculus) PubMed

 19801.

Cooperativity and homodimer stabilization of GoxA are strongly dependent on the presence of Phe-237. [GoxA] (Mus musculus) PubMed

 19802.

one of the key contributors to F. alocis complement resistance is a unique protein, FACIN (F. alocis complement inhibitor), which binds to C3, resulting in suppression of all complement pathways [FACIN] (Mus musculus) PubMed

 19803.

PTP4 is an important protein competent of the polar tube involved in the mechanism of host cell infection utilized by these pathogens. [PTP4] (Mus musculus) PubMed

 19804.

MS23 is the earliest-acting factor, upstream of bHLH51 and bHLH122, controlling tapetal specification and maturation.[MS23 protein, Zea mays] (Mus musculus) PubMed

 19805.

IPE1 participates in the putative oxidative pathway of C16/C18 omega-hydroxy fatty acids and controls anther cuticle and pollen exine development together with MALE STERILITY26 and MALE STERILITY45 in maize.[IPE1] (Mus musculus) PubMed

 19806.

Data suggest that subtilisin, a serine protease secreted by non-pathogenic bacterium Bacillus subtilis, induces plasma clotting by proteolytically activating prothrombin with single "non-canonical" cleavage at Ala470-Asn471 bond. [subtilisin] (Mus musculus) PubMed

 19807.

The study supports a conserved role of Gbeta-like/RACK/Gib2 proteins in the essential cellular process of ribosomal biogenesis and protein translation. [Gib2] (Mus musculus) PubMed

 19808.

Data suggest that NfnS and NfnL, subunits of NfnI, together exhibit NADH-dependent ferredoxin NADP+ activity oxidoreductase. [NfnS, NADH-dependent ferredoxin NADP oxidoreductase I (NfnI), subunit S; NfnS, NADH-dependent ferredoxin NADP oxidoreductase I (NfnI), subunit L] (Mus musculus) PubMed

 19809.

This is the first functional validation and association of C8ORF37 mutations with the BBS phenotype, which identifies BBS21. The zebrafish studies hereby show that C8ORF37 variants underlie clinically diagnosed BBS-related phenotypes as well as isolated retinal degeneration (Mus musculus) PubMed

 19810.

Report the crystal structure of AcrIIA4 in complex with single-guide RNA-bound SpyCas9 (s.pyogenes), thereby establishing that AcrIIA4 preferentially targets critical residues essential for PAM duplex recognition, as well as blocks target DNA access to key catalytic residues lining the RuvC pocket. (Mus musculus) PubMed

 19811.

Report the crystal structure of AcrIIA4 (L.monocytogenes) in complex with single-guide RNA-bound SpyCas9, thereby establishing that AcrIIA4 preferentially targets critical residues essential for PAM duplex recognition, as well as blocks target DNA access to key catalytic residues lining the RuvC pocket. (Mus musculus) PubMed

 19812.

Data suggest that, in B cell lymphoma, expression of MIRN30 is up-regulated in both granulocytic myeloid-derived suppressor cells and monocytic myeloid-derived suppressor cells; in B cell lymphoma, 3prime untranslated region of Socs3 appears to be direct target of MIRN30 in myeloid-derived suppressor cell differentiation. (Socs3 = suppressor of cytokine signaling 3 protein) [Mir30, microRNA 30] (Mus musculus) PubMed

 19813.

SET8, a histone methyl transferase, facilitates M2 macrophage polarization and regulates apoptosis, which contributes to Mycobacterium tuberculosis survival. (Mus musculus) PubMed

 19814.

X-ray structure of the Rgd1p-RhoGAP domain, identify by NMR spectroscopy and confirm by docking simulations, a new but cryptic phosphoinositide-binding site.[Rgd1] (Mus musculus) PubMed

 19815.

results provide evidence that the Armi and Yb coexist with Vasa and play an important role in perinuclear nuage granules formation in ovary-derived N4 cell [Armi] (Mus musculus) PubMed

 19816.

a new cry2A gene was cloned from a promising indigenous B. thuringiensis SWK1 strain that had a similarity of 94% compared to that of the known Cry2Aa protein in the NCBI database and this gene has been named as cry2Al1 by the B. thuringiensis delta-endotoxin Nomenclature Committee (Mus musculus) PubMed

 19817.

The Arenaviridae family is one of the two RNA viral families that encode a 3'-5' exonuclease in their genome. An exonuclease domain is found in the Arenaviridae nucleoprotein and targets dsRNA specifically. High-resolution structures of the Mopeia virus exonuclease domain complexed with magnesium and calcium is reported. [3'-5' exonuclease ] (Mus musculus) PubMed

 19818.

Three serial femtosecond crystallography and two synchrotron radiation structures of thermolysin have been determined at comparable resolutions in the range 1.9-2.3 A. [ thermolysin ] (Mus musculus) PubMed

 19819.

Expression of OXA-143 beta-lactamase in A. baumannii ATCC 17978 resulted in higher minimal inhibitory concentration for all antibiotics tested. [OXA-143 beta-lactamase] (Mus musculus) PubMed

 19820.

Data suggest that Nej1/Lif1 (DNA repair protein Nej1/ligase interfacing factor 1) multimer formation becomes critical at double strand break (DSB) in DNA to block hyper-resection mainly after recruitment to the DSB; Nej1 inhibits 5' DNA hyper-resection mediated by Dna2/Sgs1 (DNA helicase 2/slow growth suppressor 1). [Nej1, DNA repair protein Nej1; Dna2 = DNA helicase 2; Sgs1 = slow growth suppressor 1] (Mus musculus) PubMed

 19821.

Data suggest that pepck(mt) plays critical nodal role in linking catabolism of glucose and glutamine with anabolic pathways; pepck(mt) also plays role in cohesive operation of glycolysis and tricarboxylic acid cycle in normal glucose-replete milieu. Strain used here was Toxoplasma gondii RH. [pepck(mt), mitochondrial ATP-dependent phosphoenolpyruvate carboxykinase] (Mus musculus) PubMed

 19822.

This study revealed that a novel class of protein, calmodulin-like protein rgs-CaM, functions as an immune receptor for CMV infection and induces salicylic acid signaling, which is characteristic of immune responses against biotrophic pathogens, including viruses, and is required for systemic acquired resistance induction. [rgs-CaM] (Mus musculus) PubMed

 19823.

The Pap1 transcription factor is localized in the nucleus under nitrosative stress and not due to reactive oxygen species formation. (Mus musculus) PubMed

 19824.

Overexpression of Yorkie(CA) in the the posterior silk gland (PSG) significantly increased the weight of the PSG, and also increased the weight of the cocoon, larval body, and pupal body to decreasing degrees. (Mus musculus) PubMed

 19825.

we report the results of a genetic screen for mutants with hepatic steatosis that identified harvest moon (hmn), a locus required for late larval growth and survival in zebrafish (Mus musculus) PubMed

 19826.

A key role for Osx for bone formation in a non-mammalian species, revealing conserved and non-conserved features in vertebrate bone formation. [Osterix protein, Medaka] (Mus musculus) PubMed

 19827.

Brca2 and Rad51 prevent formation of abnormal DNA replication intermediates, whose processing by Smarcal1 and Mre11 predisposes to genome instability. (Mus musculus) PubMed

 19828.

Results show that vacA i1m1 and vacA i1m2 genotypes were strongly associated with the risk of Gastric Cancer(GC) while vacAs1/cagA+ seems to be a risk factor for Duodenal Ulcer since it is inversely associated with GC (VacA and CagA) (Mus musculus) PubMed

 19829.

These data strongly support the idea that Snf1 signaling specificity is mediated by localization of the different Snf1 isoforms.[Snf1] (Mus musculus) PubMed

 19830.

The NEU1 is involved in the production of IL-6 and MCP-1 in adipocytes possibly through TLR4/NF-kappaB signalling. ( Neu1 protein, mouse) (Mus musculus) PubMed

 19831.

These findings illustrate a novel strategy for viral interference with the SUMO pathway, and identify the EBV miR-BHRF1-1 and the cellular RNF4 as regulators of the productive virus cycle. [miR-BHRF1-1] (Mus musculus) PubMed

 19832.

MCT14 is an orphan transporter regulated by phosphate and highly enriched in kidney localizing to the luminal membrane of one specific nephron segment [MCT14 orphan transporter] (Mus musculus) PubMed

 19833.

The surface charge differences in PorB from serogroups B and C invasive and carriage strains. [PorB] (Mus musculus) PubMed

 19834.

Thus, the myxomavirus dsRNA binding protein M029 not only antagonizes PKR from multiple species but also blocks the type I IFN antiviral state independently of PKR in a highly species-specific fashion.[M029] (Mus musculus) PubMed

 19835.

ADAMTS10 is identified as a potential functional integrator of the Ikaros-CtBP chromatin remodeling network.[CtBP] (Mus musculus) PubMed

 19836.

Data suggest that, in the absence of ATP, HmuUV and HmuT bind together tightly in membrane vesicles; ATP in excess inhibits this interaction via mechanism requiring ATP hydrolysis; thus, the role of ATP in HmuUV/HmuT hetero complex appears different from its role in other bacterial ATP-binding cassette transporters. [HmuUV, hemin importer ATP-binding subunit; HmuT, hemin ABC transporter hemin-binding protein] (Mus musculus) PubMed

 19837.

secreted from epithelial cells into the midgut lumen; transcriptional and translational expression down-regulated after starvation but up-regulated after refeeding [SP36] (Mus musculus) PubMed

 19838.

Plasmodium Falciparum isolates in India have K76T mutation in the crt gene, which is hall mark for chloroquine resistance. Plasmodium Falciparum isolates in India have Y184F mutation in mdr-1 gene. [crt] [mdr-1] (Mus musculus) PubMed

 19839.

The mutations in the RNA dependent RNA polymerase play a crucial role in enhancing hepatitis E virus replication thus leading to disease severity. [RNA Dependent RNA polymerase ] (Mus musculus) PubMed

 19840.

Plasmodium falciparum kelch13 mutations conferring resistance to artemisinin in Senegal have been described. [kelch13] (Mus musculus) PubMed

 19841.

M18BP1/KNL2 is essential for centromere formation through direct binding to CENP-A nucleosome in non-mammalian vertebrates.[M18BP1] (Mus musculus) PubMed

 19842.

The R213I mutation in RF2 brings one step forward toward engineering an omnipotent RF in Escherichia coli, capable of reading all three stop codons. (RF2 protein, E coli) (Mus musculus) PubMed

 19843.

Data suggest that efficient expression of replication-dependent gamma2 late genes is, at least in part, regulated by cdk9 dependent co- and/or post-transcriptional events involving spt5 and icp27. (cdk9 [US1] = cyclin dependent kinase 9; spt5 = transcriptional elongation factor spt5; icp27 = immediate-early protein icp2 [RL2]) [spt5, transcriptional elongation factor spt5] (Mus musculus) PubMed

 19844.

confers differential high-temperature seedling-plant resistance to Puccinia striiformis f. sp. tritici - [WRKY49 and WRKY62] (Mus musculus) PubMed

 19845.

Data suggest that KcsA exhibits selective binding of K+ and other permeant species (Rb+, Cs+) over Na+; KcsA exhibits selective exclusion of non-permeant species (Na+, Li+) from binding the channel filter. [KcsA, pH-gated potassium channel KcsA] (Mus musculus) PubMed

 19846.

results suggest that miR-199a-3p may promote adipocyte proliferation, while also repressing adipocyte differentiation by down-regulating stearoyl-CoA desaturase and changing fatty acid composition during adipogenesis [mir199] (Mus musculus) PubMed

 19847.

the remodeling of transected dendritic trees by AFF-1-mediated self-fusion can be restored in old animals by daf-2 mutations, and can be differentially re-established by ectopic expression of the fusion protein AFF-1.[AFF-1] (Mus musculus) PubMed

 19848.

In an Arabidopsis quadruple mutant, in which four major sectors of the signaling network, jasmonate, ethylene, PAD4, and salicylate, are disabled, the hypersensitive response (HR) typical of effector-triggered immunity is abolished when the Pseudomonas syringae effector AvrRpt2 is bacterially delivered but is intact when AvrRpt2 is directly expressed in planta. [AvrRpt2] (Mus musculus) PubMed

 19849.

small bacterial cell size, which is signified by the absence of DivIVA, and the presence of an adhesive RrgA-containing pilus-1 mediate pneumococcal passage from the bloodstream through the BBB into the brain to cause lethal meningitis [RrgA] (Mus musculus) PubMed

 19850.

Hrip1 was able to bind to the tobacco and rice plant plasma membrane, causing rapid morphological changes at the cellular level, such as cell shrinkage and chloroplast disorganization; these findings indicate that Hrip1 is a microbe-associated molecular pattern that is perceived by the plant immune system [Hrip1] (Mus musculus) PubMed

 19851.

The cytoplasmic hydroxycinnamoyl-CoA:omega-hydroxy fatty acid transferase DPW2 plays a fundamental role in male reproduction.[DPW2] (Mus musculus) PubMed

 19852.

Study shows that V. fischeri, purified EroS, and other bacterial chondroitin lyases induce S. rosetta mating at environmentally relevant concentrations, suggesting that bacteria likely regulate choanoflagellate mating in nature. [EroS] (Mus musculus) PubMed

 19853.

A novel 58.9kDa protein of Chromobacterium piscinae, named GNIP1Aa, for Gram Negative Insecticidal Protein, was found to have specific activity against Western corn rootworm (Mus musculus) PubMed

 19854.

results are consistent with a model in which the BamA barrel dynamics induce defects in the outer membrane that facilitate insertion of nascent outer membrane proteins (OMPs) [BamA] (Mus musculus) PubMed

 19855.

Data suggest that the inactive prokaryotic leu-500 promoter [P(leu-500)] contains a single A-to-G point mutation in the -10 region of leucine operon promoter, which causes leucine auxotrophy; this promoter can be activated by (-) DNA supercoiling in Escherichia coli topA strains. [P-leu-500, leu-500 promoter] (Mus musculus) PubMed

 19856.

tubulin curvature-sensing model of microtubule depolymerization by the budding yeast kinesin-8, Kip3, is reported. [Kip3] (Mus musculus) PubMed

 19857.

Inserting the endoplasmic reticulum-targeting sequence coding region of neuraminidase into different 5' UTRs confirmed that viral RNA-binding protein NS1 can promote the translation of secretory protein mRNAs based on the nucleotides within this region rather than the resulting amino acids. (Mus musculus) PubMed

 19858.

Data suggest that sec3 stability/degradation is regulated by pib1, rpt2, ubp3, and molecular chaperones (Sks2, Ssa1). (sec3 = exocyst complex subunit sec3; pib1 = ubiquitin-protein ligase pib1; rpt2 = 19S proteasome regulatory subunit Rpt2; ubp3 = deubiquitinating enzyme ubp3) [sec3, exocyst complex subunit sec3; pib1, ubiquitin-protein ligase pib1] (Mus musculus) PubMed

 19859.

Results suggest that the regulation of miRNA expression might confer to the phenotype of the phytochrome A1 (PHYA1) RNAi line(s) with improved fiber quality: [PHYA1] (Mus musculus) PubMed

 19860.

The crucial role of these key residues suggests that gp1 might be a molecular motor driving phage assembly.[gp1] (Mus musculus) PubMed

 19861.

crystal structure of BrlR with c-di-GMP complex structure to 2.5 A [BrlR] (Mus musculus) PubMed

 19862.

A unique viral protein, vCXCL1, which targets three chemokine receptors: CXCR1 and CXCR2 expressed on neutrophils and CXCR1 and CX3CR1 expressed on Natural killer cells.[vCXCL1] (Mus musculus) PubMed

 19863.

Data suggest that hyperthermophilic TMK exhibits different conformational states along biocatalytic stages of its reaction; TMK exhibits broad substrate specificity toward phosphate group acceptor nucleotides. [TMK, thymidylate kinase] (Mus musculus) PubMed

 19864.

The data suggest that IglG is a PAAR-like protein acting as a bi-modal protein that may connect the tip of the Francisella T6SS with a putative l type VI secretion system (T6SS) effector, IglF[IglG] (Mus musculus) PubMed

 19865.

Data suggest there exists a close evolutionary relationship between restriction endonucleases type IIE (Ecl18kI) and type IIP (EcoRII) via recombination between domains with active sites and domains that recognize DNA sequences. For this study, fusion protein NCRII-18 was constructed by fusing Ecl18kI gene with part of gene coding for N-terminal domain of EcoRII. [Ecl18kI, ecl18kIR, R.Ecl18kI (restriction endonuclease)] (Mus musculus) PubMed

 19866.

Dihydroneopterin triphosphate pyrophosphatase (DHNTPase) is a member of the Mg2+ dependent Nudix hydrolase superfamily. Determined are the crystal structures of DHNTPase with and without activating, Mg2+-mimicking metals Co2+ and Ni2+. [dihydroneopterin triphosphate pyrophosphatase] (Mus musculus) PubMed

 19867.

The Ain1 showed weaker affinity to F-actin in vitro than other actin-bundling proteins in S. pombe. (ain1 protein, S pombe) (Mus musculus) PubMed

 19868.

hypoosmoregulation of the scl mutant deficient in P450c17I was analyzed.[P450c17l] (Mus musculus) PubMed

 19869.

Data suggest that a Fe(IV) intermediate catalyzes oxidation of excess Fe(II) nearby the ferroxidase center of ferritin (in the ferroxidase reaction catalyzed by ferritin); oxidation of Fe(II) substrate to Fe(III) occurs via a peroxodiferric intermediate. [ferritin, ferroxidase, ceruloplasmin] (Mus musculus) PubMed

 19870.

DFTR was composed of 301 amino acids with theoretical molecular mass and pI values of 33 kDa and 6.86. [DFTR] (Mus musculus) PubMed

 19871.

Here, the authors identify cellular nuclear transport factor 2 (NTF2)-like export protein 1 (NXT1) as a novel binding partner of nucleoprotein (NP) that stimulates NP-mediated nuclear export via the CRM1-dependent pathway.[NP] (Mus musculus) PubMed

 19872.

CmlI catalyzes six-electron oxidation of an arylamine precursor to the aryl-nitro group of chloramphenicol. Data suggest that CmlI is able to preserve efficiency and specificity while avoiding adventitious chemistry by performing the entire six-electron oxidation in one active site. [CmlI, N-oxygenase CmlI] (Mus musculus) PubMed

 19873.

WSL4 was involved in very-long-chain fatty acid elongation beyond C22 and that elongation beyond C24 required the participation of OsCER2.[WSL4, OsCER2] (Mus musculus) PubMed

 19874.

Px IV shares 58% of all residues with TcGPXII. The orthologous enzymes have in common their substrate preference for fatty acid hydroperoxides. However, the T. cruzi protein has been reported to be localized in the endoplasmic reticulum and to be specific for glutathione as reducing agent. [Px IV] (Mus musculus) PubMed

 19875.

findings show that cyclic di-GMP (c-di-GMP) upregulates expression of the eps genes encoding the Type II secretion system via the c-di-GMP-dependent transcription factor VpsR [VpsR] (Mus musculus) PubMed

 19876.

purified RasP cleaved His6-MBP-RsiW(73-118) in vitro within the RsiW transmembrane segment demonstrating that RasP is an intramembrane protease; purified RasP failed to cleave His6-MBP-FtsL(23-117); propose that the lack of alpha-helix-breaking residues in the FtsL transmembrane segment creates a requirement for the membrane environment and/or an additional protein(s) in order for RasP to cleave FtsL [RasP] (Mus musculus) PubMed

 19877.

Leishmania infantum LiSIR2rp1 was among the first non-nuclear and essential SIR2 deacetylases described in eukaryotes; study shows that the two other LiSIR2rp2 and LiSIRrp3 paralogs are both located in mitochondria. Further, genetic and biochemical evidence show that SIR2rp2 protein directly affects parasite proliferation in relation to NAD+ bioavailability. [SIR2rp2, SIRrp3] (Mus musculus) PubMed

 19878.

Mutational analyses revealed that the GerA and Ynd germination receptors function cooperatively in triggering an efficient germination response with single l-amino acid germinants, whereas the GerK germination receptor is essential for germination with d-glucose.[GerK and Ynd] (Mus musculus) PubMed

 19879.

FOXA up-regulates expression of the Cry1Ac-toxin receptor ABCC2 and ABCC3 genes. [FOXA, ABCC2] (Mus musculus) PubMed

 19880.

the first electrophysiological investigation of an NhaB Na+/H+ exchanger, is reported. [NhaB] (Mus musculus) PubMed

 19881.

the properties of Single-stranded DNA-binding protein from Staphylococcus aureus (SaSsbA, a counterpart of EcSSB) and analyzed its interaction with SaPriA, was investigated.[SsbA, PriA] (Mus musculus) PubMed

 19882.

Native Weissella cibaria (WAraf43) is a dimer, while Lactobacillus brevis DSM1269 (LbAraf43) is a tetramer in solution, and both of them show activity with similar catalytic efficiency on 1,5-alpha-l-arabinooligosaccharides: [LbAraf43] (Mus musculus) PubMed

 19883.

Results indicate that ADL posses a novel substrate binding property and may play an essential role in polyamine biosynthesis with a different mode of function from known proteins of the S-adenosylmethionine decarboxylase super family. [ADL] (Mus musculus) PubMed

 19884.

Cinnamoyl esterase showed the highest substrate specificity with methyl caffeate among other methyl esters of hydroxycinnamic acids such as methyl ferulate, methyl sinapinate, methyl p-coumarate, and methyl caffeate. [cinnamoyl esterase] (Mus musculus) PubMed

 19885.

Results show that although AslB has low similarity with other sulfatase maturating enzymes, it has all the motifs and residues required for the catalytic activity. It can bind sulfatase motif peptides with a wide sequence variation. Also, AslB activates human IDS and GALNS. [AslB] (Mus musculus) PubMed

 19886.

MdBT1 and MdBT2, interact with the MbHLH104 protein in apple.[MdBT1, MdBT2, MbHLH104] (Mus musculus) PubMed

 19887.

These results indicate that thiamine biosynthesis mediated by THI1 enhances nodule enlargement and is required for seed development in L. japonicus.[THI1] (Mus musculus) PubMed

 19888.

OsHAC1;1 and OsHAC1;2 are arsenate reductases that play an important role in restricting As accumulation in rice shoots and grain.[OsHAC1;1, OsHAC1;2] (Mus musculus) PubMed

 19889.

deletion of Rnl renders cells sensitive to gamma radiation and causes a delay in the reconstitution of the ionizing radiation -shattered genome (rnl). (Mus musculus) PubMed

 19890.

Characterization of a chitinase (Chi18A) from the cellulolytic actinomycete Thermobifida fusca has been reported. [Chi18A] (Mus musculus) PubMed

 19891.

these data reveal that EspFU of Enteropathogenic and enterohemorrhagic Escherichia coli enhances epithelial colonization by increasing actin-based motility and promoting an efficient method of cell-to-cell transmission. (Mus musculus) PubMed

 19892.

Recombinant Burkholderia thailandensis DNase II is highly active at low pH in the absence of divalent metal ions. The crystal structure of B. thailandensis DNase II shows a dimeric quaternary structure capable of binding double-stranded DNA. Each monomer of B. thailandensis DNase II exhibits a similar overall fold as phospholipase D, phosphatidylserine synthase and tyrosyl-DNA phosphodiesterase. (Mus musculus) PubMed

 19893.

The FtsH substrates SecD and ExbD are involved in transport processes across the membrane, whereas the physiological roles of YlaC and YhbT are yet unknown. The presence of the previously identified YfgM degron in two of the novel substrates suggests general rules for substrate recognition of this unique protease. [FtsH] (Mus musculus) PubMed

 19894.

Data suggest that physicochemical characteristics of GTP-binding protein 1 in E. coli cytoplasm (in cell lysates and cell extracts) can be changed by addition of oligopeptides to C-terminus; here, addition of short arginine motifs alters stickiness of GTP-binding protein 1. [typA or BipA or yihK, GTP-binding protein 1] (Mus musculus) PubMed

 19895.

Two uncharacterized genes, scfA and scfB, encoding putative membrane-associated proteins were identified in Group A Streptococcus (GAS) and might play an integral role in enhancing adaptation and fitness of GAS during localized skin infection (Mus musculus) PubMed

 19896.

a role of Defective in Exine Formation 1 (OsDEX1) in rice (Oryza sativa), a Ca(2+) binding protein, in regulating rice tapetal cell degradation and pollen formation, is reported.[OsDEX1] (Mus musculus) PubMed

 19897.

identification of conserved residues on the surface of PcrA that are likely to be directly involved in the interaction with RNA polymerase. (Mus musculus) PubMed

 19898.

Novel individual CrrB amino acid substitutions (Y31H, W140R, N141I, P151S, and S195N) were shown to be responsible for colistin resistance through CrrC. [CrrB], [CrrC] (Mus musculus) PubMed

 19899.

D14 protein works as an intercellular signaling molecule to fine-tune strigolactone function.[DWARF14] (Mus musculus) PubMed

 19900.

Epstein-Barr virus (EBV)-miR-BART6-3p, a microRNA encoded by oncogenic EBV, inhibited EBV-associated cancer cell migration and invasion by targeting and downregulating a novel long non-coding RNA LOC553103.[miR-BART6-3p] (Mus musculus) PubMed

 19901.

This is the first report of KPC-2, NDM-4 and OXA-48 producing carbapenem resistant Klebsiella pneumoniae strain from Vietnam.[KPC-2] [ NDM-4 ][OXA-48] (Mus musculus) PubMed

 19902.

CENP-A protein levels decreased through development coinciding with chromosome-size scaling. Partial loss of CENP-A protein resulted in shorter mitotic chromosomes, consistent with a role in setting chromosome length. (Mus musculus) PubMed

 19903.

The saePQRS operon was used to analyze RNase Y specificity. A RNase Y cleavage site is in an intergenic region between saeP and saeQ. RNase Y cleavage was not determined by the cleavage site sequence but by a 24-bp double-stranded recognition structure that was required to initiate cleavage 6 nt upstream. Cleavage caused rapid degradation of the upstream fragment and stabilization of the downstream fragment. saePQRS. (Mus musculus) PubMed

 19904.

experimental genetics analysis supports specialized and/or redundant role(s) for NFUapi in the [Fe-S] cluster biosynthesis pathway in the apicoplast of a malarial parasite. (Mus musculus) PubMed

 19905.

the identification of a previously uncharacterised CRK:cyclin complex between CRK12 and the putative transcriptional cyclin, CYC9. CRK12:CYC9 interact to form an active protein kinase complex in procyclic and bloodstream T. brucei. (Mus musculus) PubMed

 19906.

To understand the significance of dNTP pools increase for Polzeta function, we studied the activity and fidelity of four-subunit Polzeta and Polzeta4-Rev1 complexes in vitro at 'normal S-phase' and 'damage-response' dNTP concentrations. The presence of Rev1 inhibited the activity of Polzeta and greatly increased the rate of all three 'X-dCTP' mispairs, which Polzeta4 alone made extremely inefficiently. (DNA polymerase ... (Mus musculus) PubMed

 19907.

These results suggest that OsDR11L is a negative regulator in rice disease resistance.[OsDR11L] (Mus musculus) PubMed

 19908.

These results indicate that the 1.2-kb insertion in the OsFRDL4 promoter region in japonica subspecies is responsible for their higher expression level of OsFRDL4.[OsFRDL4] (Mus musculus) PubMed

 19909.

MYB2 represses light-harvesting protein genes in Cyanidioschyzon merolae [Myb2] (Mus musculus) PubMed

 19910.

The transcriptional levels of SACE_3398-3400 were upregulated 15- to 37-fold in the pccD gene deletion strain (DeltapccD) and downregulated 3-fold in the pccD overexpression strain (WT/pIB-pccD), indicating that PccD was a negative transcriptional regulator of SACE_3398-3400.[pccD] (Mus musculus) PubMed

 19911.

IGDB-2 binds to LGC-34, a predicted ligand-gated ion channel, and lgc-34 mutations inhibit igdb-2 suppression of daf-6.[IGDB-2, LGC-34] (Mus musculus) PubMed

 19912.

MGL-1 is the molecular driver underlying the translation of starvation signals to reproduction plasticity in an AIY neuron-specific manner.[MGL-1] (Mus musculus) PubMed

 19913.

Study reports the critical residues of globin-coupled diguanylate cyclases EcGReg from Escherichia coli and BpeGReg from Bordetella pertussis; show that their diguanylate cyclase activity requires an intact globin domain. Results suggest distal residues of the globin domain affect diguanylate cyclase activity and that BpeGReg may interact with other c-di-GMP-metabolizing proteins to form mixed signaling teams. [BpeGReg] (Mus musculus) PubMed

 19914.

we describe a NF-kappaB inhibitory virion protein of orf virus (ORFV), ORFV073, which functions very early in infected cells (Mus musculus) PubMed

 19915.

Knockdown of the Plasmodium falciparum SURFIN4.1 antigen leads to an increase of its cognate transcript. [SURFIN4.1] (Mus musculus) PubMed

 19916.

We identified a novel fucose-binding lectin designated PHL that might play a crucial role in the interaction of P. asymbiotica with both human and insect hosts (Mus musculus) PubMed

 19917.

we studied two previously uncharacterized pESI-encoded chaperone-usher fimbriae, named Ipf and Klf in Salmonella enterica serovar Infantis (Mus musculus) PubMed

 19918.

Analysis of the Cpf1 structures proposes a singular working model of RNA-guided DNA cleavage, suggesting new avenues for redesign of Cpf1. [Cpf1] (Mus musculus) PubMed

 19919.

Results demonstrate the circRNA_010567/miR-141/TGF-beta1 axis plays an important regulatory role in the diabetic mice myocardial fibrosis model [circRNA_010567] (Mus musculus) PubMed

 19920.

This study suggests that erythrocyte ADMA accumulation contributes to advanced CKD in mice via suppression of erythropoietin receptor expression. [Asymmetric dimethyarginine] (Mus musculus) PubMed

 19921.

Crystal structure of 4,6-alpha-glucanotransferase has been reported. [4,6-alpha-glucanotransferase] (Mus musculus) PubMed

 19922.

study reveals the mechanism of SpyCas9 inhibition by AcrIIA4, providing a structural basis for developing 'off-switch' tools for SpyCas9 to avoid unwanted genome edits within cells and tissues (Mus musculus) PubMed

 19923.

The domain-swapped dimer is the core structural and functional unit of type A PutA enzymes. [PutA] (Mus musculus) PubMed

 19924.

Rhodobacter sphaeroides has cytoplasmic arrays, which divide and segregate using a chromosome-associated ATPase, PpfA. The expression of the soluble chemoreceptor TlpT is shown to drive the formation of the arrays, accelerated by PpfA [TlpT]. (Mus musculus) PubMed

 19925.

AphB binds directly to its own promoter and positively controls its own expression in later growth stages. AphB also activates the expression of the exotoxin Asp by binding directly to the promoter regions of asp and the master quorum-sensing (QS) regulator luxR DNase I footprinting analysis uncovered distinct AphB-binding sites (BBS) in these promoters.[AphB, Asp, luxR] (Mus musculus) PubMed

 19926.

the activity of the ATG4 protease is finely regulated by the intracellular redox state, and it is inhibited under stress conditions to ensure lipidation of ATG8 and thus autophagy progression in C. reinhardtii.[ATG4] (Mus musculus) PubMed

 19927.

The results reveal that the majority of fluconazole non-susceptible Candida tropicalis isolates show overexpression of CDR1, MDR1, and ERG11 genes. [ERG11] (Mus musculus) PubMed

 19928.

this data identifies a novel role for ETR-1 in hermaphrodite gametogenesis and in the process of engulfment of germline apoptotic cell corpses.[ETR-1] (Mus musculus) PubMed

 19929.

Structure of the REL N-terminal domain responsible for nucleotide binding [REL] (Mus musculus) PubMed

 19930.

NDM-1 gene was identified from plasmid on Salmonella enterica serovar Indiana C629 isolate from China.[NDM-1] (Mus musculus) PubMed

 19931.

The crystal structure of the apoenzyme form of fructose-1,6-bisphosphatase ase is a homotetramer in which the dimer of dimers adopts a planar conformation with disordered "dynamic loops".[fructose-1,6-bisphosphatase] (Mus musculus) PubMed

 19932.

Glucosamine promoted Crz1 translocation from the cytoplasm to the nucleus. Interestingly, multiple components of the high osmolality glycerol response (HOG) pathway, consisting of the phosphorelay system and some of the Hog1 MAPK module, acted as repressors of glucosamine-elicited filamentation through their calcineurin-opposing effect on Crz1's nuclear translocation (Mus musculus) PubMed

 19933.

the role of PF23/DYX1C1 remains unknown, but we suggest that DYX1C1 could provide a scaffold for macromolecular assembly (Mus musculus) PubMed

 19934.

involved in integument remodelling during moulting and metamorphosis [SP95] (Mus musculus) PubMed

 19935.

The role of pncA mutations in pyrazinamide resistance (Mus musculus) PubMed

 19936.

This study shows that OxyA generates the second bis-aryl ether bond in vancomycin and that it exhibits strict substrate specificity toward the chlorinated, OxyB-cross-linked product. No OxyA product is detected with the unchlorinated substrate. Together with previous results, these data suggest that chlorination occurs after OxyB- but before OxyA-catalyzed cross-link formation. [OxyA] (Mus musculus) PubMed

 19937.

This study clarifies the role of Ate1/arginylation in stress response.[Ate1] (Mus musculus) PubMed

 19938.

cloning and expression analysis - [Yki] (Mus musculus) PubMed

 19939.

These data support a crucial role for miR-27 in promoting chondrogenic differentiation in the pharyngeal arches through regulation of FAK.[Mir27] (Mus musculus) PubMed

 19940.

a novel immune-related gene, named BmHDD1 was identified in silkworm, Bombyx mori: temporal and spatial expression profiles of BmHDD1 were analyzed, and found it mainly expressed in hemocytes and secreted into hemolymph under normal physiological conditions. [HDD1] (Mus musculus) PubMed

 19941.

Recombinant vaccinia virus expressing Ambystoma tigrinum virus eIF2alpha homologue (vIF2alphaH) partially rescued deletion of the vaccinia virus E3L gene. Rescue coincided with rapid degradation of PKR in infected cells.[vIF2alphaH] (Mus musculus) PubMed

 19942.

Coupled with increased sister chromatid recombination and Rad52 repair foci in pnk1Delta cells, these findings indicate that lingering SSBs in pnk1Delta cells trigger Rad51-independent homology-directed repair of collapsed replication forks. (Mus musculus) PubMed

 19943.

Binding of both vRNA panhandle and single strand RNA induce a conformational change in the nucleocapsid protein. Nucleocapsid protein remains in a unique conformational state due to simultaneously binding of structurally distinct vRNA panhandle and single strand RNA substrates. (Mus musculus) PubMed

 19944.

Report increased expression of BACE1-AS long noncoding RNA in the hearts of mice with ischemic heart failure and increased amyloid beta levels. (Mus musculus) PubMed

 19945.

SEM-4/SALL acts through the SoxC transcription factor SEM-2 to promote the sex myoblast fate.[SEM-2, SEM-4] (Mus musculus) PubMed

 19946.

N(5) ,N(10) -methylenetetrahydromethanopterin reductase catalyzed methylglyoxal to lactaldehyde using NADPH.[N(5) ,N(10) -methylenetetrahydromethanopterin reductase ] (Mus musculus) PubMed

 19947.

Transcription factors MtMYB3 plays a negative role in cold acclimation and Interacts with MtMYB61 in vitro and in vivo: [ MtMYB3 and MtMYB61] (Mus musculus) PubMed

 19948.

Here the authors show that LANA homologs of macaque rhadinoviruses lack the KR-rich nuclear localization signal, and instead have a large RG-rich nuclear localization signal with multiple RG dipeptides and a conserved RGG motif.[ORF73] (Mus musculus) PubMed

 19949.

Functional characterization of the DNA gyrases, gyrA and gyrB, in fluoroquinolone-resistant mutants of Francisella novicida has been presented. [gyrA], [gyrB] (Mus musculus) PubMed

 19950.

The allele frequency and distribution pattern at this locus among natural populations suggested that the wild cucumber origin of SHORT HYPOCOTYL1 (SH1) for local adaptation, which was under selection during domestication: [SH1] (Mus musculus) PubMed

 19951.

LR16 single nucleotide polymorphisms associated with wheat leaf rust resistance. [LR16] (Mus musculus) PubMed

 19952.

These results show that MutY Glycosylase relies strongly on the presence of the 8-oxo-7,8-dihydroguanine base and recognizes multiple structural features at different stages of recognition and catalysis to ensure that only inappropriately mispaired adenines are excised. [MutY Glycosylase] (Mus musculus) PubMed

 19953.

The role of blaOXA-58 carbapenemase in the antibiotic resistance and it's chromosomal location [blaOXA-58] (Mus musculus) PubMed

 19954.

MS/MS analyses of glycopeptides and deamidated, deglycosylated (PNGase F-treated) peptides from ectopically expressed VEGFR-2 in porcine aortic endothelial (PAE) cells identified N-glycans at the majority of the 17 potential N-glycosylation sites on VEGFR-2 in a site-specific manner. (Mus musculus) PubMed

 19955.

checkpoint recovery is promoted by Rtt101Mms1-mediated ubiquitylation of Mms22.[Rtt101, Mms1] (Mus musculus) PubMed

 19956.

Unlinked NS2B-NS3pro behaves better in NMR spectroscopy than linked NS2B-NS3pro, which has resulted in the backbone resonance assignment of the unlinked NS2B-NS3 complex bound to a peptidic boronic acid inhibitor. (Mus musculus) PubMed

 19957.

a novel computational framework that tightly couples continuum mechanics with continuum solvation models to study the detailed gating behavior of E. coli-MscL, is reported.[MscL] (Mus musculus) PubMed

 19958.

Ribeye makes up most of the synaptic ribbon density in neuromast hair cells and is necessary for proper localization of calcium channels and synaptic ribbons.[Ribeye A, Ribeye B] (Mus musculus) PubMed

 19959.

A strain from which both of the Mn(II) oxidase genes and fleQ were deleted exhibited low levels of Mn(II) oxidase activity. The enzyme responsible was genetically and biochemically identified as an animal heme peroxidase (AHP) with domain and sequence similarity to the previously identified Mn(II) oxidase MopA.[MopA] (Mus musculus) PubMed

 19960.

The findings from the present experiments using a pspA deletion mutant have confirmed the physiological role of phosphoserine phosphatases as serine producers and show that serine is a major donor of one-carbon units in Hydrogenobacter thermophilus.[pspA] (Mus musculus) PubMed

 19961.

This study demonstrated that the function of viral LS2b protein was remarkably affected by the interaction with host RPS11 protein.[LS2b] (Mus musculus) PubMed

 19962.

Structural analyses of the bacterial primosomal protein DnaB reveal that it is a tetramer and forms a complex with a primosomal re-initiation protein [DnaB][PriA] (Mus musculus) PubMed

 19963.

order of stability for proteolysis sites of collagen-like protein V-CL [V-CL] (Mus musculus) PubMed

 19964.

Studied the complete process of RNA polymerase (RNAP) translocation on DNA during transcription elongation by implementing extensive all-atom molecular dynamics (MD) simulations to construct a Markov state model (MSM). Our studies show that translocation proceeds in a Brownian motion, and the RNAP thermally transits among multiple metastable states. (RNA polymerase) (Mus musculus) PubMed

 19965.

The integrity of the spore envelope was severely affected in a pdtA deletion mutant, resulting in 34% nonviable spores. Also, PdtA itself or the polydiglycosylphosphate attached to the peptidoglycan by the glycopolymer transferase PdtA also has a crucial function in apical tip extension of vegetative hyphae under stress conditions.[PdtA] (Mus musculus) PubMed

 19966.

Chromosomal deletion of acmB, an S-layer-associated beta-N-Acetylglucosaminidase, resulted in aberrant cell division, autolysis, and autoaggregation.[acmB] (Mus musculus) PubMed

 19967.

These results provide evidence that BNGR-A25L and -A27 are two functional Gq-coupled receptors for Bombyx CAPA-PVKs, enabling the further elucidation of the endocrinological roles of Bom-CAPA-PVKs and their receptors in insect biology. (Mus musculus) PubMed

 19968.

results show that mycobacteria encode a non-conserved protein (lamA) that controls the pattern of cell growth, resulting in a population that is both heterogeneous and better able to survive antibiotic pressure [lamA] (Mus musculus) PubMed

 19969.

The third restriction-modification system from Thermus aquaticus YT-1 (TaqIII) has been reported. [TaqIII] (Mus musculus) PubMed

 19970.

The SmAP2 RNA binding motif in the 3'UTR affects mRNA stability in the crenarchaeum Sulfolobus solfataricus. [SmAP2] (Mus musculus) PubMed

 19971.

Here, the authors present two high-resolution structures of Helicobacter pylori XerH with its recombination site DNA difH, representing pre-cleavage and post-cleavage synaptic intermediates in the recombination pathway. The structures reveal that activation of DNA strand cleavage and rejoining involves large conformational changes and DNA bending, suggesting how interaction with the cell division protein FtsK may license (Mus musculus) PubMed

 19972.

A novel nucleoid-associated protein, GapR, coordinates chromosome replication and chromosome partition. [GapR] (Mus musculus) PubMed

 19973.

Here, the authors found that a LysR-type transcriptional regulator that we named GamR, encoded by XOO_2767 of Xanthomonas oryzae pv. oryzae strain MAFF311018, positively regulated the transcription of both hrpG and hrpX.[GamR, hrpG, hrpX] (Mus musculus) PubMed

 19974.

The authors demonstrate that the production of polyketide precursors like sorbicillinol and dihydrosorbicillinol as well as their derivatives bisorbicillinoids requires the function of a highly reducing polyketide synthase encoded by the gene Pc21g05080 (pks13).[pks13] (Mus musculus) PubMed

 19975.

we identify targets of miR-29 undergoing post transcriptional downregulation during meiotic prophase I, which likely correspond to the direct targets of miR-29. Interestingly, candidate direct targets of miR-29 are enriched in transcripts encoding extracellular matrix components. (Mus musculus) PubMed

 19976.

Results show that BamA is essential for folding and insertion of beta-barrel outer membrane proteins. Also, the five polypeptide transport-associated (POTRA) domains of BamA feature a hinge between POTRA2 and POTRA3 and that its flexibility is important for BamA in vivo function. [BamA] (Mus musculus) PubMed

 19977.

The contribution of the C5 protein to specificity for precursor tRNA is modulated by proximal 5' leader sequences.[C5 protein] (Mus musculus) PubMed

 19978.

Results show the crystal structure of FusA in its open and closed conformations bound to fructooligosaccharides (FOSs), and solution scattering data of SfuA, which delineate the structural basis for import of short- and long-chain FOSs. The structure of FusA identifies an EF hand-like calcium-binding motif which seems to be essential for translocation of FOSs in FusABC. [SfuA and FusA] (Mus musculus) PubMed

 19979.

report describes the identification of PEG344 as an unrecognized factor required for the full virulence of strain hvKP; in silico analysis suggested that PEG344 serves as an inner membrane transporter [PEG344] (Mus musculus) PubMed

 19980.

Lycopene cyclase (CruA) role in the carotenoid biosynthesis [CruA] Beta-carotene hydroxylase (CrtR) role in the carotenoid biosynthesis [CrtR] (Mus musculus) PubMed

 19981.

Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16 [Vps33][Vps16] (Mus musculus) PubMed

 19982.

Structural and Functional Analyses of Periplasmic 5'-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Aeromonas hydrophila [MtaN-1]{MtaN-2] (Mus musculus) PubMed

 19983.

A protein with so far unknown function as a hypothetical functions as redox-active cofactor in active sites of enzymes manganese (Mn) transporter (Mnx) was identified, and Mnx::yellow fluorescent protein fusion showed that the protein resides in the thylakoid membrane: [Mnx] (Mus musculus) PubMed

 19984.

The directed migration of gonadal distal tip cells depends on NGAT-1, a gene encoding a predicted beta1,4-N-acetylgalactosaminyltransferase. (Mus musculus) PubMed

 19985.

qRfg3 is a recessive resistance locus to Gibberella stalk rot that reduced the disease severity index [Rfg3] (Mus musculus) PubMed

 19986.

model illustrating how the NspS-MbaA signaling system may communicate exogenous polyamine content to the cell to control biofilm formation in the aquatic environment and within the human intestine. (Mus musculus) PubMed

 19987.

A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA (Mus musculus) PubMed

 19988.

Data suggest Cox16p is present in Cox1p assembly intermediates and in fully assembled cytochrome oxidase; Cox16p is sub-stoichiometric with Cox1p/Cox4p; Cox16p appears is present in only a fraction of assembled cytochrome oxidase. [Cox1, cytochrome c oxidase subunit 1; Cox16, cytochrome c oxidase subunit 16] (Mus musculus) PubMed

 19989.

The pseudo-atomic solution structure of BH0236 determined by small-angle X-ray scattering revealed structural insights into the nature of avid binding by the BhCBM6/56 pair and how the orientation of the active site in the catalytic module factors into recognition and degradation of beta-1,3-glucans. (Mus musculus) PubMed

 19990.

The data show that the novel BP-1b variant occurs in a relatively important proportion of Group B Streptococcus isolates of various serotypes and genomic backgrounds. [BP-1b] (Mus musculus) PubMed

 19991.

The silkworm Zuc specifically expressed in germ-related tissues and localized on mitochondria and partially co-localized with perinuclear nuage-piRNA pathway components and nuage marker protein BmVasa. [Zuc] (Mus musculus) PubMed

 19992.

The role of cytosolic glutamine synthetase1;2 in cytokinin biosynthesis [Glutamine Synthetase1;2] (Mus musculus) PubMed

 19993.

Resistance to lambda-cyhalothrin of Cx. pipiens populations appears to be largely due to the L1014F kdr mutation [kdr] (Mus musculus) PubMed

 19994.

Data suggest that a disulfide bond stabilizes DraE in an exclusively thermodynamic manner, lowering free energy of native state and with almost no effect on free energy of transition state. [DraE, fimbriae protein DraE] (Mus musculus) PubMed

 19995.

This study demonstrated that miR-122-3p and miRNA-194-5p were two sensitive biomarkers, and miR-5099 might be a specific biomarker for reflecting the liver injury induced by Airpotato yam.[miR-122-3p] (Mus musculus) PubMed

 19996.

OleB from Bacterial Hydrocarbon Biosynthesis Is a beta-Lactone Decarboxylase [OleB] (Mus musculus) PubMed

 19997.

natural selection had a key role compared with mutational bias during the evolution of the E2 gene.[E2] (Mus musculus) PubMed

 19998.

Our findings demonstrate that PfHsp70 does not possess immunomodulatory function. Furthermore, our study further confirm E. coli ClearColi and B. choshinensis as appropriate expression systems for the production of LPS-free recombinant protein. (Mus musculus) PubMed

 19999.

Data suggest that proteins pxpA (formerly ycsF), pxpB (formerly ycsJ), and pxpC (formerly ycsK), together, form the enzyme 5-oxoprolinase. Similar results were obtained with proteins from Escherichia coli. [pxpB, ycsJ, 5-oxoprolinase subunit B; pxpC, ycsK, 5-oxoprolinase subunit C] (Mus musculus) PubMed

 20000.

It is likely that H. pylori carrying high expression of sabA causes iron deficiency anemia, especially in children and adolescents who have increased daily iron demand. [sabA] (Mus musculus) PubMed

 20001.

this study demonstrated that VvPlpA is a type II secretion system-dependent secretory phospholipase A2 regulated by HlyU and CRP and is essential for the pathogenicity of V. vulnificus. (Mus musculus) PubMed

 20002.

WDP1 regulates the abscisic acid -mediated defense response to drought stress.[WDP1] (Mus musculus) PubMed

 20003.

Here, we describe the high-resolution crystal structures of the AHL binding domains of YenR and CepR2. YenR was crystallized in the presence and absence of N-3-oxohexanoyl-l-homoserine lactone (OHHL). (Mus musculus) PubMed

 20004.

GLUCORAPHASATIN SYNTHASE 1 (GRS1; 2-oxoglutarate-dependent dioxygenase) was cloned and characterized a gene encoding by genetic mapping using a mutant that genetically lacks glucoraphasatin: [GRS1] (Mus musculus) PubMed

 20005.

OspTAC2 plays a critical role in chloroplast development [pTAC2] (Mus musculus) PubMed

 20006.

AP-1 machinery mediates post-Golgi sorting of cruzipain to reservosomes in T. cruzi and that AP-1 function is important for parasite infectivity towards host cells. (Mus musculus) PubMed

 20007.

Combined with transport assays and molecular dynamics simulations, the authors propose a novel mechanism for toxic peptide ABC exporters that only requires the transient opening of the cavity for release of the peptide.[MdjD, MccJ25] (Mus musculus) PubMed

 20008.

findings show that fhuD2 expression was induced during infection in all organs analyzed and that differences in expression were observed at different time points and in different infected organs [fhuD2] (Mus musculus) PubMed

 20009.

Genetic epistasis experiments suggest that GRK-2 acts on the D2-like dopamine receptor DOP-3 to inhibit Go signaling and positively modulate NCA-1 and NCA-2 activity. [NCA-1] (Mus musculus) PubMed

 20010.

Idr1 and Idr2 are part of an extended regulatory network of four transcription factors of the bacterial DtxR family that maintains intracellular iron balance. [Idr1], [Idr2] (Mus musculus) PubMed

 20011.

OsCu/Zn-SOD gene overexpression increases the detoxification capacity of reactive oxygen species in Oryza sativa and reduces salt-induced oxidative damage.[OsCu/Zn SOD] (Mus musculus) PubMed

 20012.

The 2-mum plasmid encoded protein Raf1 regulates both stability and copy number of the plasmid by blocking the formation of the Rep1-Rep2 repressor complex. [Raf1], [Rep1], [Rep2] (Mus musculus) PubMed

 20013.

a new gene, OsLG3, as a positive regulator of grain length, which could improve rice yield without influencing grain quality, is reported. (Mus musculus) PubMed

 20014.

The results of this study indicate that Staphylococcus aureus strain Wood 46 has normal spa (staphylococcal protein A) expression, but transcribes very low levels of the srtA gene which encodes the sortase A (SrtA) enzyme. [spa], [SrtA] (Mus musculus) PubMed

 20015.

Data suggest that TEF2 undergoes a posttranslational modification in which the alpha-amino group of mono-L-glutamine is covalently linked to side chain of glutamate-45; all TEF2 molecules are modified by this glutaminylation; this posttranslational modification occurs at all stages of yeast growth; however, glutaminylation is not essential for TEF2 activity. [TEF2, EF1A, translation elongation factor EF-1 alpha] (Mus musculus) PubMed

 20016.

These results identify a novel mechanism acting downstream of muscle contraction, where YAP activates JAG2 expression in muscle fibers, which in turn regulates the pool of fetal muscle progenitors via NOTCH in a non-cell-autonomous manner.[YAP] (Mus musculus) PubMed

 20017.

In T cells, after serum deprivation HBZ induces the expression of Delta JunD isoform. HBZ induces nuclear retention of RPS25 mRNA and loss of RPS25 protein expression. HBZ bypasses translational control of JunD uORF and favors the expression of Delta JunD. HBZ. (Mus musculus) PubMed

 20018.

PhyAsr and PhyAmm have different specificities for Ins(1,2,4,5,6)P5, have identified structural features that account for this difference, and have shown that the absence of these features results in a broad specificity toward Ins(1,2,4,5,6)P5 (Mus musculus) PubMed

 20019.

GBF1 is crucial for Chikungunya virus replication.[GBF1] (Mus musculus) PubMed

 20020.

The catalytic Cys-activated mechanism was proposed based on Clostridium perfringens sortase B the X-ray structure.[sortase B] (Mus musculus) PubMed

 20021.

KREPB4 is essential for bloodstream (BF) and procyclic form (PF) growth, in vivo RNA editing, and editosome integrity, but the loss of KREPB4 has differential effects on editosome components and complexes between BF and PF cells. (KREBP4) (Mus musculus) PubMed

 20022.

Proton transport activity of cytochrome bo3 decreased with increased curvature of the membrane. Proton uptake at the N-side was insensitive to pH between pH6.4-8.4, while proton release at the P-side had an optimum pH of ~7.4. The pH optimum is related to proton release from the proton exit site. Only ~5% of the proteoliposomes containing a non-pumping mutant, E286C have fast decay after stopping turnover. Cyt bo3. (Mus musculus) PubMed

 20023.

The crystal structure of the mutant enzyme (with the replacement of active site Cys115 for His) complexed with competitive inhibitor, l-norleucine was determined at 1.45A resolution. At the enzyme active site the inhibitor was bound both noncovalently and covalently, which corresponds to the two intermediates of the gamma- and beta-elimination reactions, Michaelis complex and the external aldimine. Methioinine gamma-ly... (Mus musculus) PubMed

 20024.

This study uses high-throughput methods to measure and analyze the RNA association kinetics and equilibrium binding affinity for all possible sequence combinations in the precursor tRNA binding site of C5, the essential protein subunit of Escherichia coli RNase P. [C5 protein] (Mus musculus) PubMed

 20025.

crystal structure of 5-enolpyruvylshikimate-3-phosphate synthase (CpsEPSPS) from Colwellia psychrerythraea, a psychrophilic bacterium [EPSPS] (Mus musculus) PubMed

 20026.

results suggest that a weak interaction between Hsp47 and FKBP65 confers mutual molecular stability and also allows for a synergistic effect during collagen folding. (Mus musculus) PubMed

 20027.

Molecular dynamics simulations revealed that the catalytic domain of wild-type Cel7A and the FCA398 variant exhibit similar behavior at 300 K, whereas at elevated temperature (475 and 525 K), the FCA398 variant fluctuates less and maintains more native contacts over time. (Mus musculus) PubMed

 20028.

at normal levels of expression during bacterial infection, NleB1/NleB(CR) antagonizes death receptor-induced apoptosis of infected cells by modifying FADD in an irreversible manner. (Mus musculus) PubMed

 20029.

Structure and function of Escherichia coli PspA and Synechocystis Vipp1 N-terminal peptides in the membrane stress sensing and mitigation have been described. [Vipp1] (Mus musculus) PubMed

 20030.

structural and mechanistic findings conclusively identify a role for the AztC flexible loop in zinc acquisition from the metallochaperone AztD, yielding critical insights into metal binding by AztC from both solution and AztD. (Mus musculus) PubMed

 20031.

the conformational plasticity of DsrA represents a special mechanism small non-coding RNA employed to deal with its multiple regulatory targets of mRNA.[Dsra] (Mus musculus) PubMed

 20032.

Bacillus anthracis topoisomerase IV recognizes DNA supercoil geometry during strand passage. [topoisomerase IV] Bacillus anthracis gyrase relaxes DNA positive supercoils more rapidly than it introduces DNA negative supercoils. [gyrase] (Mus musculus) PubMed

 20033.

Dynamics of RPA during homologous recombination [RPA] (Mus musculus) PubMed

 20034.

The mechanism of how AdeR recognizes the intercistronic DNA, which leads to a diverse mode of response regulation.[AdeR] (Mus musculus) PubMed

 20035.

Data suggest that both Cqest-beta-1 (Culex pipiens) and Cqest-beta-2 (Culex quinquefasciatus) have similar affinity to bind/sequester insecticides, despite 16 amino acid differences between the two proteins; this study compared the binding of organophosphate and carbamate as ligands. [Cqest-beta-1, carboxylesterase Cqest-beta-1] (Mus musculus) PubMed

 20036.

Data suggest that both Cqest-beta-1 (Culex pipiens) and Cqest-beta-2 (Culex quinquefasciatus) have similar affinity to bind/sequester insecticides, despite 16 amino acid differences between the two proteins; this study compared the binding of organophosphate and carbamate as ligands. [Cqest-beta-2, carboxylesterase Cqest-beta-2] (Mus musculus) PubMed

 20037.

Specific enzyme activities for both hydrogen (H2) production and H2 oxidation were determined for HydA1. Although C. variablilis NC64A exhibited light-dependent H2 production activity upon sulfur deprivation, CvHydA1 did not interact in vitro with several plant-type [2Fe-2S]-ferredoxins, but only with a bacterial2[4Fe4S]-ferredoxin. (Mus musculus) PubMed

 20038.

PiggyBac transposase TPB6 is required for heterochromatin-dependent precise excision of internal eliminated sequences residing within exons of functionally important genes.[PiggyBac transposase TPB6] (Mus musculus) PubMed

 20039.

FER-5B plays an important role in enhancing tolerance to heat stress and other abiotic stresses.[FER-5B] (Mus musculus) PubMed

 20040.

We establish that the NspS/MbaA signaling complex is the dominant mediator of biofilm formation in response to extracellular norspermidine, rather than norspermidine synthesized by NspC or imported into the cell (Mus musculus) PubMed

 20041.

Results show that in T. brucei procyclic forms i) glycerol-3-phosphate acyltransferase TbDAT but not TbGAT is the physiologically relevant initial acyltransferase and ii) ether lipid precursors are primarily made by TbDAT. [TbDAT] (Mus musculus) PubMed

 20042.

report demonstrates LnqR as the first TetR-family transcriptional regulator involved inlacticin Q biosynthesis and that, as an exceptional case of TetR-family regulators, LnqR positively regulates the transcription of these biosynthetic genes [LnqR; lacticin Q] (Mus musculus) PubMed

 20043.

results show that HBZ and Tax1 dampen early IFN-beta responses, while HBZ but not Tax1 augments the expression of IFN-alpha and downstream IFN signaling, which may contribute to immunopathogenesis [HBZ] (Mus musculus) PubMed

 20044.

study describes a physical and functional interaction between Ebola virus VP40 (eVP40) and WWP1, a host E3 ubiquitin ligase that ubiquitinates VP40 and regulates virus-like particles egress.[VP40]. (Mus musculus) PubMed

 20045.

RocA is an accessory protein to the virulence-regulating CovRS two-component system in Streptococcus pyogenes. [RocA] (Mus musculus) PubMed

 20046.

FbaA and PAM had additive effects in promoting Streptococcus pyogenes survival and virulence. [FbaA], [PAM] (Mus musculus) PubMed

 20047.

A member of the ETS family of transcription factors, Nv-ERG is bi-polarily expressed prior to gastrulation. NvERG, simultaneously controls expression of two different sets of downstream targets, leading to two different embryonic gene regulatory networks (GRNs) in opposite poles of the developing embryo. NvERG. (Mus musculus) PubMed

 20048.

The study reports the structure determination of a periplasmic phosphate-binding protein from S. maltophilia. The molecule adopts the type II periplasmic binding protein (PBP) fold with a number of extensively elaborated loop regions. A fully dehydrated phosphate anion is bound tightly between the two domains of the protein and interacts with conserved residues and a number of helix dipoles. [phosphate-binding protein] (Mus musculus) PubMed

 20049.

AmpC BER is an extended substrate spectrum class C beta-lactamase with a two-amino-acid insertion in the R2 loop compared with AmpC EC2. The crystal structures of AmpC BER (S64A mutant) and AmpC EC2 were determined. [AmpC] (Mus musculus) PubMed

 20050.

Here, the structure of Clostridium thermocellum arabinofuranosidase 43A (CtAbf43A), which has been shown to act in the removal of arabinose side chains from arabinoxylan but not from pectic arabinan, is reported. [arabinofuranosidase 43A ] (Mus musculus) PubMed

 20051.

Here, crystal structures of metallochaperone CopM in apo, copper-bound and silver-bound forms are reported. Monovalent copper/silver ions are buried within the bundle core; divalent copper ions are found on the surface of the bundle. [CopM] (Mus musculus) PubMed

 20052.

The rate constants of Fd dissociation from PSI have been determined by flash-absorption spectroscopy with different combinations of cyanobacterial PSIs and Fds, and different redox states of Fd and of the terminal PSI acceptor (FAFB). Ferredoxin. (Mus musculus) PubMed

 20053.

The rate constants of Fd dissociation from PSI have been determined by flash-absorption spectroscopy with different combinations of cyanobacterial PSIs and Fds, and different redox states of Fd and of the terminal PSI acceptor (FAFB). Ferredoxin. (Mus musculus) PubMed

 20054.

HpxW is an oxamate amidohydrolase which catalyzes the conversion of oxamate to oxalate and is a member of the Ntn-hydrolase superfamily. Here, the structure of HpxW is presented and the substrate complex is modeled. In addition, the steady-state kinetics of this enzyme and two active-site variants were characterized. [HpxW] (Mus musculus) PubMed

 20055.

Here using a variety of single, double, triple and quadruple mutants of Dengue virus 4 NS5 combined with solution X-ray scattering studies, insight into the critical residues responsible for the differential flexibility of Dengue virus 4 NS5 is presented. Identified are the critical linker residues conferring differences in the compactness of NS5 from Dengue virus serotype 4 and NS5 from Dengue virus serotypes 1-3. [NS5] (Mus musculus) PubMed

 20056.

Here using a variety of single, double, triple and quadruple mutants of Dengue virus 4 NS5 combined with solution X-ray scattering studies, insight into the critical residues responsible for the differential flexibility of Dengue virus 4 NS5 is presented. Identified are the critical linker residues conferring differences in the compactness of NS5 from Dengue virus serotype 4 and NS5 from Dengue virus serotypes 1-3. [NS5] (Mus musculus) PubMed

 20057.

Here using a variety of single, double, triple and quadruple mutants of Dengue virus 4 NS5 combined with solution X-ray scattering studies, insight into the critical residues responsible for the differential flexibility of Dengue virus 4 NS5 is presented. Identified are the critical linker residues conferring differences in the compactness of NS5 from Dengue virus serotype 4 and NS5 from Dengue virus serotypes 1-3. [NS5] (Mus musculus) PubMed

 20058.

Here, the structural changes of free importin-beta crystallized in polar (salt) or apolar (Polyethylene Glycols) buffer conditions, are reported. [importin-beta] (Mus musculus) PubMed

 20059.

Crystallographic studies of Rasamsonia emersonii 3 beta-glucosidase, Cel3A revealed a highly N-glycosylated three-domain dimeric protein, as has been observed previously for glycoside hydrolase family 3 beta-glucosidases. [Cel3A] (Mus musculus) PubMed

 20060.

investigations reveal the presence of multiple Pst phosphate uptake systems that exist across three distinct operons in Nostoc punctiforme and functionally characterize the role of the gene product PstB1 as being crucial for the maintenance of phosphate accumulation [PstB1] (Mus musculus) PubMed

 20061.

The data indicate that high-affinity for LapG relies on the formation of a receptor dimer-of-dimers, rather than a simple conformational change within dimeric LapD.[LapD, LapG] (Mus musculus) PubMed

 20062.

Determined are five high-resolution X-ray structures of wild-type choline trimethylamine-lyase (CutC) and mechanistically informative mutants in the presence of choline. [CutC] (Mus musculus) PubMed

 20063.

(15)N,(13)C-labeled OmcF was produced and NMR spectroscopy was used to determine the solution structure of the protein in the fully reduced state and the pH-dependent conformational changes and to characterize the overall and internal backbone dynamics of OmcF. The structure obtained is well-defined, with an average pairwise root mean square deviation of 0.37A for the backbone atoms and 0.98A for all heavy atoms. OmcF. (Mus musculus) PubMed

 20064.

Data on loss of Fd-linked activity of NR observed in mutant forms suggest roles in Fd binding for Arg43, Arg46, Lys201, and Lys614; decreased binding affinity of NR for Fd in mutant forms compared to wild-type NR suggest roles in productive binding of Fd for Arg43, Arg46, Lys201, and Lys614. (Fd = ferredoxin from Synechococcus sp. PCC 6803; NR = nitrate reductase from Synechococcus sp. PCC 7942) [NR, nitrate reductase] (Mus musculus) PubMed

 20065.

Data on loss of Fd-linked specific activity of NR observed in mutant forms suggest roles in Fd binding for Arg43, Arg46, Lys201, and Lys614; decreased binding affinity of NR for Fd in mutant forms compared to wild-type NR suggest roles in productive binding of Fd for Arg43, Arg46, Lys201, and Lys614. (Fd = ferredoxin from Synechococcus sp. PCC 6803; NR = nitrate reductase from Synechococcus sp. PCC 7942) [Fd = ferredoxin] (Mus musculus) PubMed

 20066.

In this study, we report the X-ray structure of the periplasmic sensor domain of BaeS from Serratia marcescens FS14. The BaeS sensor domain (34-160) adopts a mixed ab-fold containing a central four-stranded antiparallel b-sheet flanked by a long N-terminal a-helix and additional loops and a short C-terminal a-helix on each side (Mus musculus) PubMed

 20067.

Here, we report the crystal structure of a deletion construct of PfLipL1 (PfLipL1Delta243-279 ) bound to lipoate, and validate the lipoylation activity of this construct in both an in vitro lipoylation assay and a cell-based lipoylation assay. (Mus musculus) PubMed

 20068.

LMM5.1 and LMM5.4, negatively affect cell death and disease resistance in rice [LMM5.1][LMM5.4] (Mus musculus) PubMed

 20069.

This study characterized the interactions between heme and each domain of Streptococcal hemoprotein receptor (Shr) and Streptococcal heme-binding protein (Shp). Our kinetic and thermodynamic analyses suggested that effective heme transfer within this system is achieved not only by affinity-based transfer but also by the difference of the binding driving force. [hemoprotein receptor, heme-binding protein] (Mus musculus) PubMed

 20070.

Here, crystal structures of DsbM from P. aeruginosa are presented, revealing that it consists of a modified thioredoxin domain containing the CXXC motif and a lid domain surrounding the CXXC motif. In a glutathione-linked structure, a glutathione molecule is linked to the CXXC motif of DsbM and is bound in an elongated cavity region in the thioredoxin domain, which is also suited for substrate peptide binding. [DsbM ] (Mus musculus) PubMed

 20071.

In the alginate-assimilating bacterium Sphingomonas sp. strain A1, an additional EfeO-like protein (Algp7) is encoded downstream of the efeUOB operon. was directly demonstrated to show an ability to bind copper ion by atomic absorption spectroscopy. Crystal structure of metal ion-bound Algp7 revealed that the metal ion is bound to the cleft surrounded by several acidic residues. [Algp7] (Mus musculus) PubMed

 20072.

The here presented structure is likely to be that of a phosphate-binding protein encoded by the S. maltophilia genome (SmPBP; PDB entry 5j1d). The nature of the phosphate-binding site of SmPBP closely resembles that of Pseudomonas fluorescens DING (PfluDING), which displays remarkable discrimination between the closely similar phosphate and arsenate ions. [phosphate-binding protein] (Mus musculus) PubMed

 20073.

Two novel lipopolysaccharide phosphoethanolamine transferases, PetL and PetK, in Pasteurella multocida, and their role in resistance to cathelicidin-2 have been reported. [PetK], [PetL] (Mus musculus) PubMed

 20074.

Specific structural changes were manifested in altered pigment-pigment or pigment-protein interactions within PSI complex in the absence of zeaxanthin and echinenone. These structural modifications of the complexes seem to destabilize the PSI trimeric complexes and eventually result in an increased propensity for monomerization. (Mus musculus) PubMed

 20075.

isolation and characterization of three new cytochrome P450 monooxygenases: CYP101J2, CYP101J3, and CYP101J4 which hydroxylate the monoterpenoid 1,8-cineole [CYP101J2, CYP101J3, CYP101J4] (Mus musculus) PubMed

 20076.

results suggest that the xrvC gene is involved in bacterial growth, and it plays a vital role in virulence by positively regulating the expression of hrp genes and non-TAL effector genes in PXO99(A) and the susceptibility gene Os8N3 in rice [xrvC]. (Mus musculus) PubMed

 20077.

K13 protein single nucleotide polymorphisms from P. falciparum from Africa [K13] (Mus musculus) PubMed

 20078.

The structure of a thermostable family 30 glucuronoxylan endo-beta-1,4-xylanase (CtXyn30A) from Clostridium thermocellum is reported. [glucuronoxylan endo-beta-1,4-xylanase] (Mus musculus) PubMed

 20079.

Bioinformatic analysis revealed putative PnpR-binding sites located in the upstream regions of genes involved in PNP degradation, carbon catabolite repression and other cellular processes. In Pseudomonas putida DLL-E4 pnpR plays a potential negative regulation role in the utilization of carbon sources [PnpR]. (Mus musculus) PubMed

 20080.

propose that the acrAB efflux pump is essential for P. salmonis survival at critical florfenicol concentrations and for the generation of antibiotic-resistant bacterial strains [AcrA; AcrB] (Mus musculus) PubMed

 20081.

Depletion of CLPABP disturbed the normal subcellular localization of HuR to stress granules, and overexpression of CLPABP induced instability of leptin mRNA by inhibiting HuR function. (Mus musculus) PubMed

 20082.

Femu2 may be useful in improving plant salt tolerance.[Femu2] (Mus musculus) PubMed

 20083.

Characterization of the GabR DNA binding mode highlights the key role of DNA bending and interactions with bases outside the canonical direct repeats, and might be of general relevance for the action mechanism of MocR transcription factors.[GabR] (Mus musculus) PubMed

 20084.

The crystal structures of Escherichia coli Branching enzyme (BE) in complex with alpha-, beta- and gamma-cyclodextrin were determined in order to better understand substrate binding. [branching enzyme] (Mus musculus) PubMed

 20085.

In this article, X-ray crystal structures of a metallocofactor- and alpha-ketoglutarate (alphaKG)-bound form of prolyl 4-hydroxylase from Bacillus anthracis (BaP4H) are reported. [prolyl 4-hydroxylase] (Mus musculus) PubMed

 20086.

This study shows that RNA protects a nucleoprotein complex against radiation damage. Specific damage manifestations were determined within the large trp RNA-binding attenuation protein (TRAP) bound to a single-stranded RNA that forms a belt around the protein. Over a large dose range, the RNA was found to be far less susceptible to radiation-induced chemical changes than the protein. [TRAP] (Mus musculus) PubMed

 20087.

study described two mutations of conserved residues in Formylglycine-Generating Enzyme (FGE) (Cys187 and Tyr273) that together increase the catalytic activity 40-fold [FGE] (Mus musculus) PubMed

 20088.

high-level expression of PA-LOX in E. coli and its structural and functional characterization, is reported.[PA-LOX] (Mus musculus) PubMed

 20089.

Heterodimerization with prozyme displaces this sequence from the active site through a complex mechanism involving a cis-to-trans proline isomerization, reorganization of a beta-sheet, and insertion of the N-terminal alpha-helix into the heterodimer interface, leading to enzyme activation.[AdoMetDC] (Mus musculus) PubMed

 20090.

chu_3220 was identified as the first gene essential for the degradation of the crystalline region but not the amorphous region of cellulose; it is a high-molecular-weight protein located on the outer surface of the outer membrane and could bind to cellulose (Mus musculus) PubMed

 20091.

The results suggest that proteolysis of HrpX is an important hrp regulatory mechanism and that xylose specifically suppresses this proteolysis, resulting in active hrp gene expression in X. oryzae pv. oryzae [HrpX]. (Mus musculus) PubMed

 20092.

role in grain development, phytic acid accumulation and lateral root formation - [ABCC13] (Mus musculus) PubMed

 20093.

Here, crystal structures of the F. novicida homologue FTN_0802, which is called FvfA, in two crystal forms are reported at 1.8 A resolution. [FvfA] (Mus musculus) PubMed

 20094.

Here, several crystal structures of the minimal catalytic region of histidine kinase WalK, an essential sensor histidine kinases from Lactobacillus plantarum that shares 60% sequence identity with its homologue VicK from Streptococcus mutans, are presented. [WalK] (Mus musculus) PubMed

 20095.

Tpk2 and Tpk3 have opposing roles in translational adaptation during heat stress.[Tpk3] (Mus musculus) PubMed

 20096.

Insight into the Rep protein complexes required for partitioning and transcriptional repression, and suggest that in addition to its transcriptional function, Raf stabilization of Rep partitioning proteins contributes to the remarkable persistence of the 2-mum plasmid. [Rep1 protein, S. cerevisiae; Rep2 protein, S. cerevisiae] (Mus musculus) PubMed

 20097.

OsMTOPVIB Promotes Meiotic DNA Double-Strand Break Formation in Rice [MTOPVIB] (Mus musculus) PubMed

 20098.

intergenic region functions as an embryo-specific asymmetric bidirectional promoter - [Def2] (Mus musculus) PubMed

 20099.

The mutant FMDV 3C protease L127P significantly increased yields of recombinant FMDV subunit antigens and produced virus-like particles in mammalian and bacterial cells. The L127P mutation represents a novel advancement for economical FMD vaccine production. (Mus musculus) PubMed

 20100.

study identifed a MORE ROOT (TaMOR) gene series containing a typical AS2/LOB domain; TaMOR are highly conserved in both nucleotide and amino acid sequences; they are involved in auxin signalling in the initiation of both lateral and crown roots;overexpression not only increased root number but also increased grain yield [TaMOR-A, TaMOR-B, and TaMOR-D] (Mus musculus) PubMed

 20101.

This study affirms that PhoPR forms functional two component system which is upregulated under phosphate starvation.[PhoP, PhoR] (Mus musculus) PubMed

 20102.

No significant associations were observed between vacA genotypes and gastric carcinoma. (Mus musculus) PubMed

 20103.

These EM studies also demonstrate that the complex exhibits considerable conformational flexibility. In conclusion, the switch I element does not significantly stabilize the MCM-MeaB complex or influence the affinity of MeaB for GTP but is required for transducing signals between MeaB and MCM. (Mus musculus) PubMed

 20104.

CAX4 regulates membrane biogenesis by coordinating lipid homeostasis with protein quality control.[CAX4] (Mus musculus) PubMed

 20105.

These results give insights into the lack of amantadine inhibition of BM2 and reveal structural diversities in this family of viral proton channels. (Mus musculus) PubMed

 20106.

the complex included GAP40, an additional myosin light chain designated essential light chain (ELC), and several other candidate components. This ELC bound the MyoA neck region adjacent to the MTIP-binding site, and both myosin light chains co-located to the glideosome. (Mus musculus) PubMed

 20107.

Exploiting the universality of COG0325 (PiPY) functions, it has been used in site-directed mutagenesis studies to shed light on disease causation by epilepsy-associated mutations in the human COG0325 gene PROSC. [PiPY] (Mus musculus) PubMed

 20108.

Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes. (Mus musculus) PubMed

 20109.

DIP2093 functions as a microbial surface component recognizing adhesive matrix molecules, and may be included among the factors that contribute to the pathogenicity of C. diphtheriae strains, independently of toxin production. [DIP2093] (Mus musculus) PubMed

 20110.

controls grain size and leaf angle by modulating brassinosteroid homeostasis - [SLG] (Mus musculus) PubMed

 20111.

The studies reveal a key regulatory hotspot on AgrC that controls the basal activity of RHK as well as the responsiveness of the system to ligand inputs. Collectively, these studies offer insights into the capacity of the RHK for adaptive evolution. (Mus musculus) PubMed

 20112.

The different LpoA structures helped explain how an outer membrane-anchored LpoA can either withdraw from or extend toward the inner membrane-bound PBP1A through peptidoglycan gaps and hence regulate the synthesis of peptidoglycan necessary for bacterial viability. (Mus musculus) PubMed

 20113.

while being firmly anchored to IscS, IscU has a pivotal motion around the interface.[IscS, IscU] (Mus musculus) PubMed

 20114.

The host factor Hfq was cloned, overexpressed, purified, crystallized and biochemically characterized. Structures of Hfq were determined in space groups P1 and P6, both to 1.5 A resolution, and nanomolar-scale binding affinities for uridine- and adenosine-rich RNAs were discovered. [Hfq] (Mus musculus) PubMed

 20115.

Bacteriophages TG1 and varphiR1-RT use both the lipopolysaccharide inner core heptosyl residues and the OmpF of Yersinia enterocolitica as phage receptors. (Mus musculus) PubMed

 20116.

The C-terminal part of LsbB is crucial for the bacteriocin activity, most probably through adequate interaction with the third transmembrane domain of the YvjB receptor. [ LsbB, YvjB] (Mus musculus) PubMed

 20117.

a temperature-sensitive albino gene, encoding a monooxygenase, affects chloroplast development at low temperatures (Mus musculus) PubMed

 20118.

results showed that AL2 is likely to be involved in the splicing of both group I and II introns; results also indicated that AL2 coordinates a subset of chloroplast-associated genes to regulate the development of chloroplast in rice [albino leaf 2 (al2)] (Mus musculus) PubMed

 20119.

The XanO4 catalyzes the oxidative transformation of an anthraquinone to a xanthone system during the biosynthesis of xantholipin. (Mus musculus) PubMed

 20120.

ERK2 and ERK5, the main MAPK drivers of AP-1 activation in Sea Anemone, down-regulated fos1 and jun1 transcription in anemones exposed to metal stress, whereas p38 MAPK, triggered transcription of jun1 but not fos1. GSK3-beta triggered transcription of AP-1 and two other stress-related genes, egr1 and hsp70. (Mus musculus) PubMed

 20121.

regulates plant growth and development through modulating the gibberellin pathway - [YABBY4] (Mus musculus) PubMed

 20122.

required for root development involving pectin modification - [TSD2] (Mus musculus) PubMed

 20123.

The transcription of hemH1 was regulated by the housekeeping sigma factor RpoD and potentially regulated by OxyR, while hemH2 appeared to be regulated by the oxidative stress-associated sigma factor RpoE2. (hemH1, hemH2 ) (Mus musculus) PubMed

 20124.

confirmed that NleB1 and EspL interacted with ensconsin in a region that corresponded to its microtubule binding domain[NleB1] (Mus musculus) PubMed

 20125.

CENH3 dynamics in early meiosis.[CENH3] (Mus musculus) PubMed

 20126.

The differential deposition of H2A.Z might play important roles in gene transcription during rice development. H2A.Z is enriched at the transcription start sites of genes.[H2A.Z] (Mus musculus) PubMed

 20127.

involved in nodulation and regulates the level of nitric oxide in Mesorhizobium loti symbiosis - [Glb1-1] (Mus musculus) PubMed

 20128.

expressed in the upper nodes, required for the distribution of Fe in the panicles through solubilizing Fe deposited in the apoplastic part of nodes (Mus musculus) PubMed

 20129.

Tsac_1705 is identified as the main Ferredoxin:NAD+ Oxidoreductase in T. saccharolyticum. [Tsac_1705 ] (Mus musculus) PubMed

 20130.

The expression of iss and irp2 proteins in E. coli isolated from the liver and kidney of chickens with colibacillosis was studies; the use of these genes as markers to distinguish avian pathogenic E. coli from avian fecal E. coli is discussed [iss;irp2]. (Mus musculus) PubMed

 20131.

silencing enhances the accumulation of suberin polyester and associated wax in tuber skin - [NAC103] (Mus musculus) PubMed

 20132.

RsgA exploits its distinct GTPase pocket and specific interactions with the 30S to coordinate GTPase activation with the maturation state of the 30S subunit. [RsgA] (Mus musculus) PubMed

 20133.

The results suggest that the replicative helicase complex without GAN may become unstable and ineffective in replication fork progression (GAN). (Mus musculus) PubMed

 20134.

Csx1, a dual domain ribonuclease, is activated upon binding of an RNA ligand carrying four continuous adenosines at the 3'-end. (Mus musculus) PubMed

 20135.

CagA can alter gut microbiota and exacerbate cell proliferation and immune phenotypes previously attributed to H. pylori infection[caga] (Mus musculus) PubMed

 20136.

translation of nanos1 after fertilization requires Dead-end 1 (Dnd1), a vertebrate-specific germline RNA-binding protein and binding the eIF3 complex [eIF3] (Mus musculus) PubMed

 20137.

N. europaea alters the translation profile and regulates its growth using the MazF family of endoribonuclease under certain stressful conditions [MazF] (Mus musculus) PubMed

 20138.

This review focuses on the wide range of VacA actions that are detectable in vitro, as well as actions of VacA in vivo that are relevant for H. pylori colonization of the stomach and development of gastric disease [VacA] (Mus musculus) PubMed

 20139.

E. chaffeensis secretes Etf-1 to induce autophagy to repurpose the host cytoplasm and capture nutrients for its growth through RAB5 and class III PtdIns3K, while avoiding autolysosomal killing.[Etf-1] (Mus musculus) PubMed

 20140.

Mycobacterial WhiB6 differentially regulates ESX-1 and the Dos regulon to modulate granuloma formation and virulence in zebrafish. [WhiB6] (Mus musculus) PubMed

 20141.

CaMK-related kinase (TgCaMKrk) exhibits calmodulin-independent autophosphorylation and substrate phosphorylation activity. [TgCaMKrk] (Mus musculus) PubMed

 20142.

Arl1 and Ypt6 participate in autophagy by targeting the Golgi-associated retrograde protein (GARP) complex to the phagophore assembly site to regulate the anterograde trafficking of Atg9.[Arl1, Ypt6] (Mus musculus) PubMed

 20143.

TrwC mediated a 10-fold increase in the rate of plasmid DNA transfer to human cells and a 100-fold increase in the rate of chromosomal integration of the transferred DNA.[TrwC] (Mus musculus) PubMed

 20144.

The global transcription factor Lrp is necessary for virulence when injected into Manduca sexta or Drosophila melanogaster insect hosts. [Lrp] (Mus musculus) PubMed

 20145.

The non-Smad JNK signaling pathway, which is downstream of Nodal signaling, regulates nuclear movement independently of the Smad pathway, and this nuclear movement is associated with Smad signal transduction toward the nucleus.[Nodal] (Mus musculus) PubMed

 20146.

These results demonstrate clearly that CsSTS is involved in phloem loading, carbohydrate distribution and tolerance of cucumber seedlings to low temperature stress.[CsSTS] (Mus musculus) PubMed

 20147.

study characterized the expression pattern of the gene encoding the 77-nt sRNA MmgR and provide evidences of the influence of the growth medium nitrogen (N) source in the control of mmgR promoter activity (Mus musculus) PubMed

 20148.

these results indicate a significant difference in chromatin modifications between the rice varieties that regulates differential expression of OsBZ8 gene during salt stress.[OsBZ8] (Mus musculus) PubMed

 20149.

VacA targets myeloid cells and T-cells to directly and indirectly prevent H. pylori-specific T-cell responses and immune control of the infection [review]. (Mus musculus) PubMed

 20150.

results suggest that CasK/R activates desA expression during B. cereus growth at low temperature, allowing an optimal unsaturation of the fatty acids; desA expression was repressed during the lag phase at low temperature in presence of unsaturated fatty acids in a CasK/R-independent manner [CasK] (Mus musculus) PubMed

 20151.

Methylglyoxal synthase regulates cell elongation via alterations of cellular methylglyoxal and spermidine content in Bacillus subtilis [mgsA] (Mus musculus) PubMed

 20152.

results showed that NarE of Neisseria gonorrhoeae is a functional enzyme that possesses key features of bacterial ADP-ribosylating enzymes [NarE]. (Mus musculus) PubMed

 20153.

functional characterization and role in regulating development and immunity - [OsRLCK57 and OsRLCK107 and OsRLCK118 and OsRLCLK176] (Mus musculus) PubMed

 20154.

findings show that DnpA is an integral inner membrane protein containing 2 transmembrane domains, with the major C-terminal part located at the cytoplasmic face; correct insertion into the inner membrane is necessary for DnpA to promote fluoroquinolone tolerance; the membrane localization of DnpA further supports its role in cell envelope-associated processes [DnpA] (Mus musculus) PubMed

 20155.

The authors show CyRPA interacts directly with PfRh5.[CyRPA] (Mus musculus) PubMed

 20156.

PepN was abundantly found in culture filtrates of both wild-type and atg deletion strains, indicating that the secretion of PepN is independent of the autophagy machinery in Aspergillus niger and hence most likely occurs via a different mechanism [PepN]. (Mus musculus) PubMed

 20157.

The relationship between vacA genotypes and the development of human disease [review]. (Mus musculus) PubMed

 20158.

results suggest that novel mutations in NalC, including Arg97-Gly and Ala186-Thr, are related to MexAB-OprM overexpression causing aztreonam resistance in P. aeruginosa environmental isolates [NalC]. (Mus musculus) PubMed

 20159.

results suggest that the leucine-rich repeat containing protein that is encoded by LMOh7858_0369 might be a novel virulence factor of the L. monocytogenes H7858 strain [LMOh7858_0369] (Mus musculus) PubMed

 20160.

These results suggested the direct role of AfsQ1/Q2 in regulating coelimycin production in Streptomyces coelicolor, which is directly mediated by the structural genes, but not the cluster-situated regulatory genes, and also implied that other unknown mechanisms may be involved in AfsQ1/Q2-mediated regulation of coelimycin P2 biosynthesis [AfsQ1]. (Mus musculus) PubMed

 20161.

Atg38 and its human ortholog NRBF2, accessory components of complex I consisting of Vps15-Vps34-Vps30/Atg6-Atg14 (yeast) and PIK3R4/VPS15-PIK3C3/VPS34-BECN1/Beclin 1-ATG14 (human), were characterized.[Atg38] (Mus musculus) PubMed

 20162.

PhaM is responsible for maximal activity of PhaC, for initiation of polyhydroxybutyrate granule formation at discrete regions in the cells, and for association of formed PHB granules with the nucleoid.[PhaM, PhaC] (Mus musculus) PubMed

 20163.

High levels of Lrp promote mutualistic activities with the Steinernema carpocapsae nematode host. [Lrp} (Mus musculus) PubMed

 20164.

TsdC lipoprotein was found to mediate membrane attachment of TsdA and to ensure its full catalytic activity. It is concluded that the TsdAC complex predominantly acts as a tetrathionate reductase in vivo [TsdC, TsdA] (Mus musculus) PubMed

 20165.

PfCyRPA adopts a 6-bladed beta-propeller structure with similarity to the classic sialidase fold, but it has no sialidase activity and fulfills a purely non-enzymatic function.[CyRPA] (Mus musculus) PubMed

 20166.

Overall, obtained results demonstrated that naturally occurred InlB internalin domain variants differed in their ability to support intragastric infection in mice [InlB]. (Mus musculus) PubMed

 20167.

Study identified 2 XerA-binding sites (dif1 and dif2) in the Thermoplasma acidophilum chromosome; dif2, but not dif1, serves as a target site for XerA-mediated chromosome resolution. Mutational analysis indicated that not only the core consensus sequence of dif2, but also its flanking regions play important roles in the recognition and recombination reactions mediated by XerA. (Mus musculus) PubMed

 20168.

in addition to defining mRNA stability, components of the Ccr4-Not imprinting complex regulate RNA translatability, thus ensuring global gene expression homeostasis.[Not1, Not5, Ccr4] (Mus musculus) PubMed

 20169.

fish irisin can act directly at the pituitary level to inhibit GH transcript expression via multiple signaling pathways.[Irisin] (Mus musculus) PubMed

 20170.

we investigated how Azorhizobium caulinodans regulates ROS resistance. We found that in-frame deletions of a gene encoding the putative catalase-peroxidase katG or a gene encoding a LysR-family regulatory protein, oxyR, exhibited increased sensitivity to H2O2 We then showed that OxyR positively regulated katG expression in an H2O2-independent fashion [oxyR]. (Mus musculus) PubMed

 20171.

up-regulation contributes to seed germination heterosis by promoting cell expansion - [ZmABA8ox1b] (Mus musculus) PubMed

 20172.

data presented here establish CmpA as a novel virulence factor of L. pneumophila that is required for efficient intracellular replication in both mammalian and protozoan hosts [CmpA] (Mus musculus) PubMed

 20173.

Overgrowth amino acid substitutions partially released the growth repression caused by the N-terminal Rht-B1c insertion. Their functional importance in different GA responses and species highlights the value of the ovg alleles in elucidating DELLA function in different organs and growth responses.[Rht,DELLA] (Mus musculus) PubMed

 20174.

The central role of PrtS was confirmed by analyzing the derivative strain UC8547Delta16, whose prtS gene was interrupted by an insertional mutation, thereby making it incapable of biofilm formation. PrtS, acting as a binding substance between the milk proteins adhered to stainless steel and S. thermophilus cell envelopes, mediates biofilm formation in dairy environments [PrtS]. (Mus musculus) PubMed

 20175.

data make it doubtful that CrlA acts as the receptor for MPBD (4-methyl-5-pentylbenzene-1, 3-diol) signalling during the development of Dictyostelium discoideum Ax2 [CrlA] (Mus musculus) PubMed

 20176.

characterized a LuxR family regulator, RifZ, as a direct transcriptional activator for the rif cluster; as RifZ directly regulates the transcription of the entire rif cluster, it is considered a pathway-specific regulator for rifamycin biosynthesis [RifZ]. (Mus musculus) PubMed

 20177.

Results demonstrated that EsrB plays important roles in the reactive oxygen species resistance pathway in E. piscicida grown in Luria-Bertani broth conditions [EsrB]. (Mus musculus) PubMed

 20178.

Suppression of IL-12p70 formation by IL-2 or following macrophage depletion causes T-cell autoreactivity leading to CNS demyelination in HSV-1-infected mice. [IL-12p70] (Mus musculus) PubMed

 20179.

The results presented here suggest that Slm35 plays an important role connecting mitochondrial function with cytosolic responses and cell adaptation to stress and aging.[SLM35] (Mus musculus) PubMed

 20180.

the bifunctional receptor kdPd that regulates K(+) uptake in Escherichia coli is a dual sensor, which modulates its autokinase and phosphatase activities in response to both extracellular and intracellular K(+) concentration.[KdPd] (Mus musculus) PubMed

 20181.

Our targeting rate with Cpf1 from Acidaminococcus at high RNA concentrations (42-100% of founders) is significantly higher than at low RNA concentrations (0-21%), and is consistent with other studies that used a variety of delivery methods for Cpf1-medicated targeting in mice. (Mus musculus) PubMed

 20182.

These data reveal a novel role for Gpx3 in mitochondrial redox regulation and protein homeostasis.[Gpx3] (Mus musculus) PubMed

 20183.

the COG1738 family member YhhQ is essential for preQ transport.[YhhQ] (Mus musculus) PubMed

 20184.

Results provide evidence that the N-terminal segment of DicB plays an essential functional role on cell growth and morphology, in contrast to its C-terminal tail. [DicB] (Mus musculus) PubMed

 20185.

Crystallization and X-ray diffraction analysis of an L-arabinonate dehydratase from Rhizobium leguminosarum bv. trifolii and a D-xylonate dehydratase from Caulobacter crescentus has been described. [d-xylonate dehydratase] (Mus musculus) PubMed

 20186.

Crystal structure of AibC, a reductase involved in alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus, has been reported. [AibC] (Mus musculus) PubMed

 20187.

Crystallization and X-ray diffraction analysis of an L-arabinonate dehydratase from Rhizobium leguminosarum bv. trifolii and a D-xylonate dehydratase from Caulobacter crescentus has been described. [l-Arabinonate dehydratase] (Mus musculus) PubMed

 20188.

These data demonstrate functional cooperation between Sox6 and Nfix in regulating MyHC-I expression during prenatal muscle development.[MyHC-1] (Mus musculus) PubMed

 20189.

The crystal structure of SF216 represents a homotrimer stabilized by intersubunit interactions and ion-mediated electrostatic interactions. Each subunit consists of three beta-strands and five alpha-helices with the beta-beta-beta-alpha-alpha-alpha-alpha-alpha topology. (Mus musculus) PubMed

 20190.

Ufd1-Npl4 recruits Cdc48 to ubiquitylated CMG at the end of chromosome replication, thereby driving the disassembly reaction.[Ufd1, Npl4, Cdc48, CMG helicase] (Mus musculus) PubMed

 20191.

Analysis of double mutants defective in tubulin polyglutamylation and different regions of the N-DRC indicate B-tubule polyglutamylation and the distal lobe of the linker region are both important for axonemal integrity and normal N-DRC function. (Mus musculus) PubMed

 20192.

A recombinant DNA vaccine, pVAX-LAMP/Gn was previously proved efficient, requiring long-term evaluations. pVAX-LAMP/Gn established memory responses within a long-term protection. Lysosome-targeted strategy showed promise on Gn-based DNA vaccine and further investigations are warranted in other immunogenic Hantaviral antigens [Gn]. (Mus musculus) PubMed

 20193.

The paired cystathionine-beta-synthase (CBS) domains of OpuCA bound to c-di-AMP, and a crystal structure revealed a putative binding pocket for c-di-AMP in the cleft between the two CBS domains. Thus, c-di-AMP inhibits osmoprotection through multiple mechanisms. (Mus musculus) PubMed

 20194.

the crystal structure of a mutant of Bacillus subtilis QueF, which reveals an unanticipated intramolecular disulfide formed between the catalytic Cys55 and a conserved Cys99 located near the active site, is reported.[QueF] (Mus musculus) PubMed

 20195.

Ptc7p-driven dephosphorylation rescues Cit1p activity.[Ptc7] (Mus musculus) PubMed

 20196.

Crystallization and X-ray diffraction analysis of VcmN, a MATE transporter from Vibrio cholera, has been reported. [VcmN] (Mus musculus) PubMed

 20197.

2.9 A X-ray structure of the complete Escherichia coli KdpFABC complex with a potassium ion within the selectivity filter of KdpA and a water molecule at a canonical cation site in the transmembrane domain of KdpB [kdpF, kdpA, kdpB, kdpC] (Mus musculus) PubMed

 20198.

Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum has been solved. [aspartate transcarbamoylase] (Mus musculus) PubMed

 20199.

Data strongly indicate that UspC is a carbohydrate-binding unit of the essential UspABC transporter system, with a substrate preference for sugars containing an amino group at the C2 or C3 position. [UspC] (Mus musculus) PubMed

 20200.

confers broad-spectrum resistance by activating priming - [LecRK-S.5] (Mus musculus) PubMed

 20201.

work demonstrated that E. rhusiopathiae could recruit host plasminogen via SpaA [SpaA]. (Mus musculus) PubMed

 20202.

Skn7 affects A. flavus CA14 morphological development, stress response, aflatoxin production, and pathogenicity. (Mus musculus) PubMed

 20203.

Three of them are associated with the Hedgehog (HH) signaling pathway regulating vertebrate morphogenesis. A comparison between FBDs and East Asian breeds also revealed diversifying selection on the BBS6 gene, which was earlier shown to cause snout shortening and dental crowding via disrupted HH signaling (Mus musculus) PubMed

 20204.

In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors.[RhlR] (Mus musculus) PubMed

 20205.

PACRG and its interactors are part of a signaling pathway that includes the central apparatus, radial spokes and specific inner dynein arm subforms to control dynein-driven microtubule sliding. (Mus musculus) PubMed

 20206.

Data suggest that LigY belongs to amidohydrolase superfamily, unlike previously characterized meta-cleavage hydrolases (alpha/beta-hydrolase superfamily); catalytic mechanism of LigY likely involves substrate tautomerization, substrate-assisted activation of water for hydrolysis, and formation of gem-diol intermediate. [LigY, LigY hydrolase, meta-cleavage hydrolase LigY] (Mus musculus) PubMed

 20207.

The crystal structure of the CzcS sensor domain (CzcS SD) in complex with Zn(II) at 1.7 A resolution. [CzcS] (Mus musculus) PubMed

 20208.

OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis (Mus musculus) PubMed

 20209.

The carboxyl terminal domain of SpEAF is not only important for growth of cells under normal conditions, but also for survival in the presence of DNA damaging agents. The amino-terminal domain of SpEAF is required for interaction with SpELL, while the ability to cause transcriptional activation was present in three different regions of the SpEAF protein. [EAF] (Mus musculus) PubMed

 20210.

results report a novel bromodomain-histone recognition by TbBDF2-BD and imply that TbBDF2 may serve as a potential chemotherapeutic target for the treatment of trypanosomiasis. (Mus musculus) PubMed

 20211.

These findings reveal a role for MOAP-1 in Fas signaling in the liver by promoting MTCH2-mediated tBid recruitment to mitochondria.[tbid] (Mus musculus) PubMed

 20212.

changes in distinct lipid ratios may converge on ARF1 to increase SBP-1/SREBP-1 activity.[ARF1.2, SBP-1] (Mus musculus) PubMed

 20213.

Atg19 disassembles the propeptide trimer and forms a 2:1 heterotrimer, which not only blankets the Ape1 aggregates but also regulates their size.[Ape1, Atg19] (Mus musculus) PubMed

 20214.

EspG interaction with Arf6 blocked signaling to ARNO while EspG binding of Arf1 impeded collaboration with Rac1, thereby inhibiting WAVE regulatory complex recruitment and activation.[EspG] (Mus musculus) PubMed

 20215.

TbAMPKalpha1 activation balances quiescence, proliferation, and differentiation.[AMPKalpha1] (Mus musculus) PubMed

 20216.

1.65 A resolution structure of the AraC-family transcriptional activator ToxT from Vibrio cholerae has been reported. [ToxT] (Mus musculus) PubMed

 20217.

A putative siderophore-interacting protein from the marine bacterium Shewanella frigidimarina NCIMB 400 has been cloned, expressed, purified, and its crystallization and X-ray diffraction analysis reported. [SFRI_RS12295] (Mus musculus) PubMed

 20218.

The authors characterized Vtn gene expression in response to inflammatory stimuli in fish. Their results suggested a potential role of PoVtn in regulating fish innate immunity (PoVtn). (Mus musculus) PubMed

 20219.

HECT-like E3 ubiquitin ligase (PyHEUL) plays a role in parasite growth and/or virulence (PyHEUL). (Mus musculus) PubMed

 20220.

a high-affinity interaction between recombinant Ccr4-Not and Mmi1, is reported.[Ccr4, Not,MMi1] (Mus musculus) PubMed

 20221.

BECN1/Beclin 1 binding to viral phosphoprotein (P) induced an incomplete autophagy via activating the pathways CASP2-AMPK-AKT-MTOR and CASP2-AMPK-MAPK by decreasing CASP2.[P phosphoprotein] (Mus musculus) PubMed

 20222.

a high-affinity interaction between recombinant Ccr4-Not and Mmi1, is reported.[Ccr4, Not,MMi1] (Mus musculus) PubMed

 20223.

Reduction potentials of protein disulfides and catalysis of glutathionylation and deglutathionylation by glutaredoxin enzymes (Mus musculus) PubMed

 20224.

Data suggest that CLIPA14 (a trypsin-like serine protease) is a hemolymph protein that is rapidly cleaved/activated in the immune response following systemic infection with E. coli, S. aureus, S. marcescens, or Plasmodium berghei; female Anopheles gambiae strain G3 were used in these studies. [CLIPA14, Clip domain serine protease CLIPA14] (Mus musculus) PubMed

 20225.

PGRP-S4 can recognize and hydrolyse bacterial peptidoglycans, increases prophenoloxidase activation to a higher level in the presence of some pathogen-associated molecular patterns, and can also disrupt bacterial cell walls (PGRP-S4). (Mus musculus) PubMed

 20226.

the zebrafish GR beta-isoform does not have a functional role in transcriptional regulation.[GR beta] (Mus musculus) PubMed

 20227.

a CONSTANS-like gene, confers drought sensitivity through regulation of senescence - [Ghd2] (Mus musculus) PubMed

 20228.

ATP-driven and AMPK-independent autophagy reported in trypanosome brucei.[AMPK] (Mus musculus) PubMed

 20229.

Cdk1 first phosphorylates Cdc5 to activate it in early anaphase, and then, in late anaphase, further phosphorylation of Cdc5 by Cdk1 is needed to promote its MEN-related functions.[Cdc5, Cdk1] (Mus musculus) PubMed

 20230.

Coat protein modulates the accumulation of 2b protein and antiviral silencing. [2b protein} (Mus musculus) PubMed

 20231.

Muscle-enriched, long noncoding RNA Chronos mediates skeletal muscle hypertrophy. (Mus musculus) PubMed

 20232.

DAF-21 study explores the role and contribution of MAP Kinase pathway and its regulator protein DAF-21 involvement in the immunity against opportunistic pathogen P. mirabilis infection. (Mus musculus) PubMed

 20233.

H3.3 positively contributes to diverse lifespan-extending signaling pathways, with potential implications on age-related processes in multicellular organisms.[H3.3] (Mus musculus) PubMed

 20234.

the previously uncharacterized gene RL4716 has been experimentally demonstrated to be important to the normal cellular functioning of R. leguminosarum that is consistent with a role for the gene in the proper functioning of the cell envelope [RL4716] (Mus musculus) PubMed

 20235.

c-di-GMP regulates chemotaxis by binding to the PilZ domain protein MapZ to alter the methyltransferase activity of its protein partner CheR, fleshing out the c-di-GMP signaling network of the opportunistic pathogen Pseudomonas aeruginosa. (Mus musculus) PubMed

 20236.

Functional role of putative critical residues in Mycobacterium tuberculosis RNase P protein [Rnase P] (Mus musculus) PubMed

 20237.

X-ray crystallographic studies of the extracellular domain of the first plant ATP receptor, DORN1, and the orthologous protein from Camelina sativa, have been presented. [DORN1] (Mus musculus) PubMed

 20238.

The wblA(gh) gene of S. ghanaensis appears to play a negative role in the control of moenomycin biosynthesis and is essential for sporulation. (Mus musculus) PubMed

 20239.

findings show that three pleiotropic regulatory genes for Streptomyces morphogenesis and antibiotic production-bldA, adpA and absB-exert multi-layered control over moenomycin biosynthesis [bldA, adpA,absB] (Mus musculus) PubMed

 20240.

moeH5 encodes an homologue of the glutamine amidotransferase (GAT) enzyme superfamily. It is responsible for the observed diversity of terminally decorated moenomycins. (Mus musculus) PubMed

 20241.

Tbl1 and Tbl2 role in the leaf blight resistance and xylan acetylation [Tbl1] [Tbl12] (Mus musculus) PubMed

 20242.

NS3-mediated cleavage of FAM134B blocks the formation of endoplasmic reticulum and viral protein-enriched autophagosomes.[NS3] (Mus musculus) PubMed

 20243.

DisA: DisA is necessary to coordinate responses to replicative stress; it could help to circumvent damaged template bases that otherwise impede fork progression. (Mus musculus) PubMed

 20244.

3alpha-Hydroxysteroid dehydrogenase/carbonyl reductase catalyzes the reaction of cyclohexanol with NAD(+) based on the observed rapid equilibrium ordered mechanism and equal deuterium isotope effects of 3.9 on V and V/K for cyclohexanol. (Mus musculus) PubMed

 20245.

These results suggest that Cfs1p and flippases function antagonistically in membrane trafficking pathways. A growth assay to assess sensitivity to duramycin, a phosphatidylethanolamine (PE)-binding peptide, suggested that the cfs1Delta mutation changed PE asymmetry in the plasma membrane. Cfs1p may thus be a novel regulator of phospholipid asymmetry (Mus musculus) PubMed

 20246.

In contrast to Zea mays SUT1, UmSrt1 has a high affinity for sucrose and is relatively pH- and voltage-independent. [Srt1] (Mus musculus) PubMed

 20247.

Phosphatidylserine is necessary for Pkc1 signaling due to its role in regulating the localization of Pkc1 as well as the physical interaction between Rho1 and Pkc1.[Rho1, Pkc1] (Mus musculus) PubMed

 20248.

mutations in sirtuin2 increase the stability of the conserved catalytic sirtuin domain, thereby increasing the catalytic efficiency of the mutant enzymes.[Sirtuin2] (Mus musculus) PubMed

 20249.

Study developed a 3-color single-molecule FRET assay to study interaction of Hsp90 with a fluorescently labeled reporter nucleotide in detail, demonstrated that cross effects of different interaction partners (in this case, nucleotide binding and Aha1) have to be taken into account to understand the Hsp90 chaperone machinery to its full extent and that co-chaperones most likely affect more than step in the cycle. [Hsp90] (Mus musculus) PubMed

 20250.

The 2308DeltagntR was significantly attenuated in macrophages and mice and induced protective immune response during infection, suggested that 2308DeltagntR mutant is an attractive candidate for the design of a live attenuated vaccine against Brucella. (Mus musculus) PubMed

 20251.

Expression and Characterization of Hyperthermostable Exopolygalacturonase RmGH28 from Rhodothermus marinus. (Mus musculus) PubMed

 20252.

nucleo-cytoplasmic dynamics and transcriptional activity of CrzA are driven by apical signals transmitted by calmodulin and calcineurin.[Calcineurin, CrzA] (Mus musculus) PubMed

 20253.

Characterization and 1.57 A resolution structure of the key fire blight phosphatase AmsI from Erwinia amylovora has been reported. [AmsI] (Mus musculus) PubMed

 20254.

The crystal structure of the endoglucanase Cel10, a family 8 glycosyl hydrolase from Klebsiella pneumonia, has been reported. [Cel10] (Mus musculus) PubMed

 20255.

In response to acetic acid stress, marked differences were found in the regulons controlled by CgHaa1 and by its S. cerevisiae ScHaa1 ortholog, demonstrating a clear divergent evolution of the two regulatory networks. The results gathered in this study significantly advance the understanding of the molecular mechanisms underlying the success of C. glabrata as a vaginal colonizer. (Mus musculus) PubMed

 20256.

The beta-sliding clamp was mutated to destabilize the dimer interface to see if the formation of an open clamp loader-clamp complex depends on spontaneous clamp opening events. Mutation of a positively charged Arg at the beta-dimer interface and high NaCl destabilize the clamp, but neither facilitates the formation of an open clamp loader-clamp complex. The clamp loader actively opens the beta-sliding clamp. DnaN. (Mus musculus) PubMed

 20257.

The CDI toxin from Escherichia coli NC101 was determined in ternary complex with its cognate immunity protein and EF-Tu. It binds exclusively to domain 2 of EF-Tu, partially overlapping the site that interacts with the 3'-end of aa-tRNA. It cleaves the single-stranded 3'-end from tRNAs that contain guanine discriminator nucleotides. It induces conformational changes in EF-Tu. CDI. (Mus musculus) PubMed

 20258.

In circular minichromosomes some replication forks are able to go beyond 10 consecutive potential replication fork barriers suggesting that shortage of Fob1p limits their efficiency to block replication forks. Neighbor DNA sequences and the relative abundance of Fob1 modulate the efficiency of rRFBs to stall replication forks. Fob1. (Mus musculus) PubMed

 20259.

2 Zn2+ atoms bind to Pcf11 at separate zinc-binding domains located on each side of the Clp1 recognition region. The 2d zinc-binding domain forms an unusual zinc finger fold. The 2 domains are not mandatory for CF IA assembly nor RNA polymerase II transcription termination, but are rather involved to different extents in the pre-mRNA 3'-end processing mechanism. Pcf11. (Mus musculus) PubMed

 20260.

The structures of Nrd1 RNA binding domain and its complexes with three GUAA-containing RNAs were determined. RNA binding energetics were determined. The Nrd1 structure shows an RRM domain fused with a 2d alpha/beta domain formed by 2 non-consecutive segments at each side of the RRM. Nrd1 has a slight preference for GUAA over GUAG. The Nrd1 RNA binding domain might play a role in non-coding RNAs transcription terminatio... (Mus musculus) PubMed

 20261.

In the present study, the metK encoding S-adenosyl-L-methionine synthase from E. coli K-12 (W3110) was cloned and ligated into the plasmid pET-28a, giving the recombinant plasmid pET-28a-metK, which was then transformed into E. coli BL21 (DE3). The transformant that could effectively produce SAM was screened and identified. [metK] (Mus musculus) PubMed

 20262.

molecular modeling studies of UvrB protein from H. pylori are carried out with homology modeling and molecular dynamics (MD) simulations. The results reveal that the predicted structure is bound to a DNA hairpin with 3-bp stem, an 11-nucleotide loop, and 3-nt 3' overhang. (Mus musculus) PubMed

 20263.

These findings contribute to our understanding of how the inhibition of APC(Cdc20) activity and enhanced Cdc20 degradation are required for proper spindle checkpoint arrest.[Cdc20] (Mus musculus) PubMed

 20264.

Allotropin/Allotropin like neuropeptides are involved in multiple stage- and sex-specific functions during the development of B. mori.[Allotropin] (Mus musculus) PubMed

 20265.

The mechanism for oxygen reduction in cytochrome c dependent nitric oxide reductase (cNOR) as obtained from a combination of theoretical and experimental results has been reported. [NOR] (Mus musculus) PubMed

 20266.

Adult-plant stripe rust resistance in Chinese wheat cultivar Zhoumai 22 is controlled by a single gene, temporarily designated YrZH22. YrZH22 is located between markers WGGB105 and WGGB112 on chromosome arm 4BL. [YrZH22] (Mus musculus) PubMed

 20267.

Structural characterization of the Streptococcus pneumoniae carbohydrate substrate-binding protein SP0092 has been reported. [SP0092] (Mus musculus) PubMed

 20268.

Crystallization of FcpA from Leptospira, a novel flagellar protein that is essential for pathogenesis. [FcpA] (Mus musculus) PubMed

 20269.

This study evaluated the clinical risk factors and molecular mechanisms of carbapenem resistance in clinical isolates of P. aeruginosa; loss of functional OprD protein tended to occur in isolates with increased imipenem resistance.[OprD] (Mus musculus) PubMed

 20270.

Similarities in the structure of the transcriptional repressor AmtR in two different space groups suggest a model for the interaction with GlnK. [AmtR] (Mus musculus) PubMed

 20271.

data provide the first molecular basis for the specific interaction of peptidoglycans (PGNs) with PknB and firmly establish PGNs as the effective ligands of PknB [PknB] (Mus musculus) PubMed

 20272.

Expression, purification, crystallization and structural insights of cystathionine gamma-synthase (CGS) from the hyperthermophilic Sulfolobus tokodaii have been reported. [CGS] (Mus musculus) PubMed

 20273.

The molecular packing of the crystal showed a right-handed double-helical arrangement of pseudoazurin (Paz) molecules and hence of blue copper sites. [Paz] (Mus musculus) PubMed

 20274.

Data show molecular and structural interaction of Magnaporthe oryzae AVR-Pia-rice RGA5 and the role of the RATX1 decoy domain of RGA5: [AVR-Pia] (Mus musculus) PubMed

 20275.

RYGB in lean pigs increases the response of GIP, total GLP-1, and insulin, but reduces levels of active GLP-1 in response to an oral glucose load. These data challenge the role of active GLP-1 as a contributor to remission from diabetes after RYGB (Mus musculus) PubMed

 20276.

BUL1 expression affects leaf angel and grain size. [BUL1] (Mus musculus) PubMed

 20277.

The crystallographic structure of a rice (Oryza sativa) cellulose synthase, OsCesA8, plant-conserved region, one of two unique domains in the catalytic domain of plant CesAs, was solved to 2.4 A resolution. [CesA8] (Mus musculus) PubMed

 20278.

Yr78 was mapped to wheat chromosome 6B and might be responsible for adult plant resistance to stripe rust. [Yr78] (Mus musculus) PubMed

 20279.

Key features required for membrane tubulation and scission by Atg18 are shared by other PROPPINs, suggesting that membrane scission may be a generic function of this protein family.[Atg18] (Mus musculus) PubMed

 20280.

OsPPR6, a Pentatricopeptide Repeat (PPR) protein, regulates early chloroplast biogenesis and participates in editing of ndhB and splicing of ycf3 transcripts in rice. [OsPPR6] (Mus musculus) PubMed

 20281.

Crystal structure of the N-terminal anticodon-binding domain of the nondiscriminating aspartyl-tRNA synthetase from Helicobacter pylori has been reported. [aspartyl-tRNA synthetase] (Mus musculus) PubMed

 20282.

Multimeric Mechanosensitive Membrane Channels [MscS][MscL] (Mus musculus) PubMed

 20283.

Structure of Methylobacterium extorquens malyl-CoA lyase shows that CoA-substrate binding correlates with domain shift. [malyl-CoA lyase] (Mus musculus) PubMed

 20284.

These data indicate that while expression of PB1-F2 protein can induce inflammatory events, the capacity to generate memory CD8(+) T cells specific for immunodominant viral epitopes remains uncompromised.[PB1-F2] (Mus musculus) PubMed

 20285.

pUL10 is a newly identified immunomodulatory protein encoded by Human cytomegalovirus.[pUL10] (Mus musculus) PubMed

 20286.

Multidrug resistance was observed in P. aeruginosa ATCC 9027 associated with a deletion of nfxB protein (nfxB) induced by moxifoxacin.[nfxB] (Mus musculus) PubMed

 20287.

A pivotal functional role for conserved eIF3k and eIF3l accessory subunits of eIF3 in the regulation of cellular and organismal responses to ER stress and aging. [eIF3I protein, C. elegans] (Mus musculus) PubMed

 20288.

PHO2 is under redox control by thioredoxins Trxh1 and both Trxh1 and PHO2 are involved in phosphate homeostasis [Trxh1] [pho2] (Mus musculus) PubMed

 20289.

Discovery of a novel nitric oxide binding protein, NosP, and nitric-oxide-responsive signaling pathway in Pseudomonas aeruginosa has been described. [NosP] (Mus musculus) PubMed

 20290.

The combination of complete functional loss (nonsense mutation) in one homeologous HMA4 gene and the functional reduction in the other HMA4 gene (missense mutation) is proposed as strategy to limit cadmium leaf accumulation without developmental effects.[HMA4.1, HMA4.2]] (Mus musculus) PubMed

 20291.

The results show that Trhfb3 has a role in vegetative growth and asexual development in T. reesei. [Trhfb3] (Mus musculus) PubMed

 20292.

C-terminal domain dissection of NppL revealed that the last fifty amino acids play a critical role in determining substrate specificity of polyene-specific hydroxylation (NppL) (Mus musculus) PubMed

 20293.

analysis of the RavZ and LC3 complex reveals the mechanism for deconjugation of LC3 on the phagophore membrane [RavZ] (Mus musculus) PubMed

 20294.

Knockout of the CHLI1 gene resulted in complete loss of MgCh activity, absence of chlorophyll, acute light sensitivity, and, as a consequence, down-regulation of tetrapyrrole biosynthesis and photosynthesis-associated nuclear genes. Silencing of CHLI2 in the wild-type background did not result in any changes in the accumulation of tetrapyrrole intermediates or of chlorophyll.[CHLI2] (Mus musculus) PubMed

 20295.

MMA1 is required for secretory granule maturation. [MMA1] (Mus musculus) PubMed

 20296.

study demonstrates that PhoU2, but not PhoU1, in S. epidermidis regulates bacterial growth, biofilm formation, oxidative stress, and drug tolerance in association with alterations to inorganic phosphate metabolism, the pentose phosphate pathway, galactose metabolism, the tricarboxylic acid or citric cycle, glycolysis and gluconeogenesis, and respiratory reactions[PhoU2] (Mus musculus) PubMed

 20297.

overexpressing Odc1p, a conserved oxodicarboxylic acid carrier located in the mitochondrial inner membrane, fully restores oxidative phosphorylation in a yeast model (taz1Delta) of Barth syndrome.[Odc1] (Mus musculus) PubMed

 20298.

Here, we designed and synthesized a dual-target peptidic HIV-1 fusion inhibitor, 4HR-LBD-VIRIP, in which 4HR-LBD is able to bind to the gp41 NHR domain, while VIRIP is able to interact with gp41 fusion peptide (Mus musculus) PubMed

 20299.

Our results indicate that BbVmaH plays an important role in sustaining not only vacuolar acidification but also cytosolic calcium accumulation, ambient pH homeostasis, in vitro asexual cycle and virulence in B. bassiana (Mus musculus) PubMed

 20300.

We show that XprG is present in the nucleus. We conclude that, like mammalian mitochondrial hexokinase, HxkC has anti-apoptotic activity and the XprG transcription factor has a pro-apoptotic role in filamentous fungi. (Mus musculus) PubMed

 20301.

These results suggest that HCVcp-induced age-dependent PPARalpha activation increases synthesis of sulfatides and the resulting sulfatide accumulation affects HCV-related liver cancer. (Mus musculus) PubMed

 20302.

These findings suggest that prokaryotic pprI gene expression in mammalian cells could enhance radioresistance in vitro and in vivo. (Mus musculus) PubMed

 20303.

Taken together, these results indicated that FgPLC1 is important for hyphal growth, plant infection, and sexual or asexual reproduction, and it may be functionally related to MAP kinases in F. graminearum (Mus musculus) PubMed

 20304.

TcCYC6 expression and degradation are finely regulated in T. cruzi. [TcCYC6] (Mus musculus) PubMed

 20305.

we used live-cell imaging to demonstrate that the phospholipid flippases DnfA and DnfB, which preferentially localize to the outer and inner layers, respectively, exhibit different dynamics in the Spitzenkorper of Aspergillus nidulans (Mus musculus) PubMed

 20306.

These results suggest that CaMca1 and Edc3 play essential roles in the oxidative stress-induced apoptosis and virulence of C. albicans, and also support the notion that Edc3 is a key regulator of CaMca1 expression. (Mus musculus) PubMed

 20307.

Purification, characterization, and crystallization of phosphate-binding protein (PBP) from Polaromonas JS666 has been reported. [PBP] (Mus musculus) PubMed

 20308.

Crystallization and X-ray diffraction analysis of SpaE, a basal pilus protein from the gut-adapted Lactobacillus rhamnosus GG, has been reported. (Mus musculus) PubMed

 20309.

We show that in addition to the complex I bound fraction, ACPM1 is present as a free matrix protein and in complex with the soluble LYRM4(ISD11)/NFS1 complex implicated in Fe-S cluster biogenesis (Mus musculus) PubMed

 20310.

(MCT8) In MCT8 deficient animals, there was impaired cell proliferation, migration and differentiation in the optic tectum. (Mus musculus) PubMed

 20311.

Our results suggest that PKS and NRPS metabolism plays a significant role in M. robertsii virulence, depresses conidium production, and contributes marginally to resistance to oxidative stress and iron homeostasis, but has no significant antibacterial effect (Mus musculus) PubMed

 20312.

Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA has been reported. [Cpf1] (Mus musculus) PubMed

 20313.

Crystal structure of the N-terminal domain of VqsR from Pseudomonas aeruginosa at 2.1 A resolution has been reported. [VqsR] (Mus musculus) PubMed

 20314.

Crystallization and X-ray analysis of full-length nisin immunity protein NisI from Lactococcus lactis in a lipid-free form has been reported. [NisI] (Mus musculus) PubMed

 20315.

the Flv2/Flv4 heterodimer supports photosystem II (PSII) PSII functionality, while the Sll0218 protein assists PSII assembly and stabilization, including optimization of light harvesting.[Sll0218] (Mus musculus) PubMed

 20316.

VacA mediates CagA phosphorylation through RPTPalpha in AZ-521 cells.[VacA, CagA] (Mus musculus) PubMed

 20317.

Crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2 has been reported. [MCR-2] (Mus musculus) PubMed

 20318.

VdRACK1-null mutants lost the ability to penetrate intact cotton roots. However, the mutant strain was able to infect root-wounded cotton plants and, intriguingly, resulted in a hypervirulent phenotype, implicating a role for VdRACK1 in the restriction of rampant growth within the plant. (Mus musculus) PubMed

 20319.

These results showed that Vayg1 is necessary for melanin and microsclerotium production, and we may thus hypothesize that the Vayg1 product may catalyze two different precursors, one of which is essential for DHN melanin production and the other one is involved in a signal network for microsclerotial formation in V. dahliae (Mus musculus) PubMed

 20320.

Legionella pneumophila RavZ extracts LC3-PE from the membrane before deconjugation. RavZ initially recognizes the LC3 molecule on membranes via its N-terminal LC3-interacting region (LIR) motif.[RavZ] (Mus musculus) PubMed

 20321.

SQR was located on the cytoplasmic side of the membrane and PDO2 was a soluble protein in the cytoplasm with a tendency to be peripherally located near the membrane.[SQR, PDO2] (Mus musculus) PubMed

 20322.

amino acid residues critical for DNA binding and inducer recognition in CbnR [CbnR] (Mus musculus) PubMed

 20323.

greater carbonic anhydrase activity contributes to higher gm in northern P. trichocarpa genotypes, but other diffusion pathway components may also be involved.[Carbonic anhydrase] (Mus musculus) PubMed

 20324.

Based on the findings, the authors designate the Chlamydia trachomatis gene product corresponding to ct694-ctl0063translocated membrane-associated effector A (TmeA). Overall, the data reveal a role of TmeA during chlamydial invasion that manifests independently of effects on AHNAK.[TmeA] (Mus musculus) PubMed

 20325.

Further, cell lysis and biofilm formation were governed by the SrrAB two-component regulatory system. Data presented support a model wherein SrrAB-dependent biofilm formation occurs in response to the accumulation of reduced menaquinone.[SrrAB] (Mus musculus) PubMed

 20326.

The authors exclude presumed roles for RhopH2 and CLAG3 in erythrocyte invasion but implicate a RhopH3 contribution either through ligand-receptor interactions or subsequent parasite internalization.[RhopH2, RhopH3] (Mus musculus) PubMed

 20327.

Based on the roGFP2-hGrx1 signals, glutathione-dependent redox potentials of -267mV and -328mV, respectively, were obtained. Employing these novel tools, initial studies on the effects of redox-active agents and clinically employed antimalarial drugs were carried out on both organelles (Mus musculus) PubMed

 20328.

In glurp, in northern India, extensive variation was observed with eleven different alleles based on the AAU repeats. [glurp protein, Plasmodium falciparum] (Mus musculus) PubMed

 20329.

characterization of a thermostable glycoside hydrolase family 36 alpha-galactosidase (Aga36) (Mus musculus) PubMed

 20330.

The expression of the tia gene in the Escherichia coli K-12 strain JM109 was not sufficient, in its own right, to confer to this strain the ability to invade cell monolayers, suggesting that at least another factor must be involved in the invasion ability displayed by the subtilase-encoding pathogenicity island-positive strains.[tia] (Mus musculus) PubMed

 20331.

Altogether, these results suggest that the degradative and cytotoxic activities exhibited by StmPr1 may contribute to Stenotrophomonas maltophilia pathogenesis in the lung by inducing tissue damage and inflammation.[StmPr1] (Mus musculus) PubMed

 20332.

These results suggest that IL-17A plays an important role in host survival against Toxoplasma gondii infection by protecting the host from an anaphylactic reaction via the downregulation of Toxoplasma gondii HSP70 and IFN-gamma production.[HSP70] (Mus musculus) PubMed

 20333.

UPF1 regulates the circadian clock by modulating the splicing of frq through spliceosome and spliceosome-related arginine/serine-rich splicing factors. (Mus musculus) PubMed

 20334.

Data indicate there were 51 genes activated and 28 repressed directly by NtcA: [NtcA] (Mus musculus) PubMed

 20335.

NleL-induced JNK ubiquitylation, particularly mono-ubiquitylation at the Lys 68 residue of JNK, impairs JNK's interaction with an upstream kinase MKK7, thus disrupting JNK phosphorylation and activation.[ NleL] (Mus musculus) PubMed

 20336.

The mechanism of S. mansoni-induced regulatory B cell development involves a direct targeting of B cells IPSE/alpha-1. [IPSE] (Mus musculus) PubMed

 20337.

LrbS activates LrbA which further promotes the expression of lrbR in response to sodium lactate. (LrbS, Lrb, -LrbR) (Mus musculus) PubMed

 20338.

In the yeast two hybrid assay system, the protein interaction domains were identified as being within the N-terminal amino acids 1-30 and C-terminal amino acids 17-60 for VP2 and the N-terminal amino acids 46-60 and C-terminal amino acids 1-7 for VP3.[VP2, VP3] (Mus musculus) PubMed

 20339.

Var gene expression is modified by host antibodies. [var] (Mus musculus) PubMed

 20340.

C. albicans Aif1, as a mitochondria-localized protein, plays a dual role in the regulation of cell death under different concentrations of the stress-caused agents.[Aif1] (Mus musculus) PubMed

 20341.

Study describes the X-ray crystal structures of GtmA-apo, GtmA complexed to S-adenosylhomocysteine and GtmA complexed to S-adenosylmethionine, providing mechanistic insights into Aspergillus fumigatus' self-resistance against gliotoxin. Results reveal the extreme risk associated with intracellular dithiol gliotoxin biosynthesis-in the absence of an efficient dismutation capacity. [GtmA] (Mus musculus) PubMed

 20342.

The authors observed that the mouse cytomegalovirus encoded protein m18 is necessary and sufficient to drive expression of the RAE-1 family of NKG2D ligands. RAE-1 is transcriptionally repressed by histone deacetylase inhibitor 3 (HDAC3) in healthy cells, and m18 relieves this repression by directly interacting with Casein Kinase II and preventing it from activating HDAC3. (Mus musculus) PubMed

 20343.

Calnexin (ClxA)is required for normal growth and conidiation under the calcium-limiting condition.[ClxA] (Mus musculus) PubMed

 20344.

QKI-5 was found to be an important regulator of STAT3 stabilization and vascular endothelial growth factor receptor 2 (VEGFR2) activation during the endothelial cell differentiation process.[QKI-5] (Mus musculus) PubMed

 20345.

ROM1 is an active protease that is involved in microneme protein GP900 cleavage.[ROM1, GP900] (Mus musculus) PubMed

 20346.

ADIP1 and its interacting partner RLP1 antagonistically regulate the ABA-dependent defense signalling response to drought stress. [ADIP1, RLP1] (Mus musculus) PubMed

 20347.

Vag8 binding to human C1-inhibitor (C1-inh) interferes with the binding of C1-inh to C1s, C1r and MASP-2, resulting in the release of active proteases that subsequently cleave C2 and C4 away from the bacterial surface.[Vag8] (Mus musculus) PubMed

 20348.

These findings indicate that both the Sse acetylhydrolase and streptolysin S are required but that neither is sufficient for inhibition of neutrophil recruitment and systemic infection by hypervirulent group A streptococcus.[Sse, sagA] (Mus musculus) PubMed

 20349.

Clumping factor A (ClfA), which contains N1, N2, and N3 binding domains, was found to be a potent human T cell activator. (Mus musculus) PubMed

 20350.

In iono/osmoregulatory epithelia, larvae exhibited tissue-specific alterations in mega mRNA and Kune protein abundance, but not sinu or nrx IV mRNA. These studies provide a first look at the potential contribution of integral septate junction components to iono/osmoregulatory homeostasis in an aquatic invertebrate. [mega, Kune, sinu, nrxIV] (Mus musculus) PubMed

 20351.

the results showed that srm1 gene contributes to cell cycle regulation as well as stress response in S. pombe. [srm1] (Mus musculus) PubMed

 20352.

Results revealed the trimeric structure of HspQ in the crystal. The HspQ trimer revealed an acidic surface suitable to interact with basic proteins and suggested that HspQ functions as a heat shock protein in E. coli. [hspQ] (Mus musculus) PubMed

 20353.

Results show the molecular cloning and characterization of a new protein belonging to the family of relaxases MOBV1 Proteins. MobSag is able to cleave DNA at a specific dinucleotide. It is encoded by HRC-IMESag-rpsI, a mobile element which is able to promote plasmid transfer among pneumococcal strains. [mobSag] (Mus musculus) PubMed

 20354.

Present findings provide evidence for an interaction between melatonin and NO in their effect on seedling growth under salt stress accompanying differential modulation of two SOD isoforms, i.e. Cu/Zn SOD and Mn SOD. (Mus musculus) PubMed

 20355.

SAGA could mediate transcription from at least some TATA-like elements independently of Taf1p/TFIID.[Taf1] (Mus musculus) PubMed

 20356.

expression of chrASO in S. oneidensis and E. coli significantly improves Chromate(VI) reduction.[chrASO] (Mus musculus) PubMed

 20357.

The heme of gFlHb has a peroxidase-like environment resembling that of the well-characterized E. coli flavohemoglobin HMP. gFlHb has two Fe-His stretching modes, a feature that also occurs in type I/II-peroxidases in which a proximal histidine with strong imidazolate character and a nearby carboxylic acid residue can exist as a tautomeric pair depending on the position of a shared proton. [gFlHb] (Mus musculus) PubMed

 20358.

Icd2 gene encodes a functional IDH, and is involved in virulence as well as bacterial attachment. [Icd2] (Mus musculus) PubMed

 20359.

miR393a plays a role in coleoptile elongation and stomatal development via modulation of auxin signalling during seed germination and seedling establishment under submergence. (Mus musculus) PubMed

 20360.

Results show that HBwx was present in 72 % of the liver tumor tissues and mainly expressed in the nucleus. HBwx showed a promoting effect on tumorigenesis and growth in vivo and in vitro as well as cell migration and invasion through RKIP-p-ERK pathway. [wx] (Mus musculus) PubMed

 20361.

Data suggest that ES7c cleavage in 25S ribosomal RNA is an early and sensitive marker of oxidative stress/increased ROS levels in S cerevisiae; changes in ribosomes may be involved in adaptive response to oxidative stress; ES7c cleavage is not part of unfolded protein response or apoptosis. (ES7c = c loop of the expansion segment 7 of 25S ribosomal RNA) [RDN25, 25S ribosomal RNA] (Mus musculus) PubMed

 20362.

Translin and Trax differentially regulate telomere-associated transcript homeostasis. Trax (Tfx1) serves to maintain elevated levels of transcripts from telomeric repeats. (Mus musculus) PubMed

 20363.

These studies establish that light-regulated c-di-GMP synthesis by a bidomain construct of Tlr0924 is modulated by a flexible linker region between the two domains without formation of a stable dimer. [Tlr0924] (Mus musculus) PubMed

 20364.

NtMPK4L was activated by wounding; however, a constitutively active salicylic acid-induced protein kinase kinase did not phosphorylate NtMPK4L. Moreover, a tyrosine residue in the MEY motif was not involved in NtMPK4L activation. NtMPK4L-silenced plants showed rapid transpiration caused by remarkably open stomata.[MPK4L] (Mus musculus) PubMed

 20365.

Activities of the enzymes in the Brown Planthopper Glutathione S-Transferase and carboxylesterase (CarE) were increased at concentrations below the LC50 of ferulic acid. [Glutathione S-Transferase, CarE] (Mus musculus) PubMed

 20366.

Hepatitis C virus core protein causes dysfunction of glucose and lipid metabolism in liver cells through HOTAIR-Sirt1 signalling pathway. [ core protein ] (Mus musculus) PubMed

 20367.

RML1 encodes a ribosome large subunit protein 3B (RPL3B) in rice by means of map-based cloning and genetic complementation. RPL3B is abundantly expressed in all the tissues, whereas RPL3A, another RPL3 gene family member, is expressed at low levels.[RML1,RPL3A,RPL3B] (Mus musculus) PubMed

 20368.

findings show that the consensus BY kinase Walker A and B domains, the RK cluster, and the YC domain of Ptk1 are necessary for autophosphorylation and for substrate phosphorylation [Ptk1]. (Mus musculus) PubMed

 20369.

Data (from studies using TCR-F50/GIL/HLA-A2) suggest there are multiple solutions to recognizing identical peptide-MHC ligand with sufficient affinity to elicit broad anti- influenza virus response protective against viral escape. (TCR-F50 = GIL-specific T-cell receptor, alpha-beta; HLA-A2 major histocompatibility complex class I A; GIL = immunodominant influenza A virus epitope from M1) [M1, influenza A virus protein M1] (Mus musculus) PubMed

 20370.

Data suggest that cytoplasmic glucosyltransferase Glt1 (glucosyltransferase Glt1) exhibits substrate specificity that includes glycosylation of Skp1 (S-phase kinase associated protein Skp1), a subunit of SKP cullin F-box protein ligase, an E3 ubiquitin ligase; knockout of Glt1 leads to grown deficit. [Glt1, glucosyltransferase Glt1; Skp1, S-phase kinase associated protein Skp1] (Mus musculus) PubMed

 20371.

The genomic structures of JfIFN3 and JfIFN4 are composed of 5 exons and 4 introns. JfIFN4 has 2 conserved cysteine residues, while JfIFN3 has 4. JfIFN3 and JfIFN4 showed the highest amino acid sequence identities to turbot IFN1 (74%) and IFN2 (62%), respectively.[IFN3,IFN4] (Mus musculus) PubMed

 20372.

the glycerol synthetic enzyme Gpd1 is involved in the post-translational modification of Tcp-1 (subunit of TRiC) by acetylation and glycation through the NAD(+)/NADH shuttle and the triose phosphate intermediate dihydroxyacetone phosphate, respectively.[Gpd1, Tcp-1] (Mus musculus) PubMed

 20373.

bmp15l, figla, smc1bl, and larp6l are preferentially expressed in germ cells in Atlantic salmon (Salmo salar L.). (Mus musculus) PubMed

 20374.

Data show that the expression of miRNAs and Dicer1 were downregulated in cells lines expressing HTLV-I HBZ protein (HBZ) as well as in fresh CD4 (+) cells from acute adult T cell Leukemia (ATL) patients: [HBZ] (Mus musculus) PubMed

 20375.

Study examined for the first time, the transcriptional activity and regulation of a DNA region within the 5' upstream of pou5f3 in fish ES cells in vitro. Results suggest that the transcription factors and cis-acting regulatory elements underlying the Pou5f1 homolog expression appear to be conserved across vertebrate phyla. [pou5f3] (Mus musculus) PubMed

 20376.

functional implications inferred from the recently resolved crystal structure of Oryza sativa Phytoene desaturase in a complex with norflurazon, are reported.[Phytoene desaturase] (Mus musculus) PubMed

 20377.

The structure of the NpTrpDH monomer, which exhibited high similarity to that of l-Glu/l-Leu/l-Phe dehydrogenases, consisted of a substrate-binding domain (domain I, residues 3 to 133 and 328 to 343) and an NAD(+)/NADH-binding domain (domain II, residues 142 to 327) separated by a deep cleft. (TrpDH) (Mus musculus) PubMed

 20378.

MoEnd3 plays a critical role in mediating receptor endocytosis that is critical for the signal transduction-regulated development and virulence of M. oryzae. [MoEnd3] (Mus musculus) PubMed

 20379.

AvrRxo1 phosphorylates NAD in planta, and that its kinase catalytic sites are necessary for its toxic and resistance-triggering phenotypes. [AvrRxo1] (Mus musculus) PubMed

 20380.

The role of CPK17 in rice cold stress response [CPK17] (Mus musculus) PubMed

 20381.

These results suggest that T. forsythia GroEL is a novel virulence factor that can contribute to inflammatory bone resorption caused by T. forsythia and synergizes with IL-17 to exacerbate inflammation and bone resorption [GroEL]. (Mus musculus) PubMed

 20382.

results showed that the MaCrz1 gene played important roles in cell wall integrity, stress tolerance, and virulence, and provides clues as to the genes and pathways targeted by the transcription factor [Crz1] (Mus musculus) PubMed

 20383.

recorded for the plants challenged with the both bacteria. This study suggests a relationship between the upregulation of nta-miR167, nta-miR393 and accumulation of flavanoid compounds. Overall, the expression of these miRNAs as well as flavonoid derivatives has the potential of being used as biomarkers for the interaction of B. subtilis and A. tumefaciens model system in N. tabacum. (Mus musculus) PubMed

 20384.

Data suggest that a distinct pool of phosphatidic acid in the endoplasmic reticulum is required for regulation of localization of phosphorylated Opi1 and thus phospholipid metabolism in yeast. [Opi1, transcriptional regulator Opi1] [REVIEW] (Mus musculus) PubMed

 20385.

(770)DYWL(773) of extracellular loop 4 comprise a putative binding site to Bacillus thuringiensis Cry1Aa toxin (ABCC2) (Mus musculus) PubMed

 20386.

TRDMT1 mediated C38 methylation of aspartic acid tRNA might play a critical role by translational regulation of important proteins and modulate the pathogenicity of the malarial parasite. (Mus musculus) PubMed

 20387.

The receptor-like protein ELR mediates extracellular recognition of the elicitin domain, a molecular pattern that is conserved in Phytophthora species.[ELR] (Mus musculus) PubMed

 20388.

It was concluded that the enhanced luteal PGF2alpha content due to increased prostaglandin F2alpha synthase (PGF2alpha synthase)expression after flutamide administration might contribute to premature corpus luteum regression.[PGF2alpha synthase] (Mus musculus) PubMed

 20389.

EBL gene controlled the growth rate in the blood stages of the parasites. [EBL] (Mus musculus) PubMed

 20390.

PFLU2693, annotated as a haloacid dehalogenase-like enzyme, is a new sugar phosphate phosphatase, now designated Spp, which is able to dephosphorylate a range of phosphate substrates, including glucose 6-phosphate and fructose 6-phosphate, in vitro.[spp] (Mus musculus) PubMed

 20391.

Identify Kaposi sarcoma virus miR-K12-1 as an oncogene which activates NF-kappaB/IL-6/STAT3 signaling pathway, promoting tumorigenesis. (Mus musculus) PubMed

 20392.

Data suggest that periplasmic transaminase PtaA is a homodimeric enzyme using cofactor pyridoxal phosphate to convert glutamic acid to alpha-ketoglutaric acid; the enzyme from P. fluorescens A506 was used in these studies. [PtaA, periplasmic transaminase PtaA] (Mus musculus) PubMed

 20393.

HaABCA2 plays a key role in mediating toxicity of both Cry2Aa and Cry2Ab Bt toxins against Helicoverpa armigera (Mus musculus) PubMed

 20394.

The protein, which is probably involved in stress response, has been crystallized and X-ray analyzed in the first structure elucidation of a mycobacterial SSBb. In spite of the low sequence identity between SSBas and SSBbs in mycobacteria, the tertiary and quaternary structure of the DNA binding domain of MsSSBb is similar to that observed in mycobacterial SSBas (Mus musculus) PubMed

 20395.

These investigations suggest that Hsp90 may be the critical binding partner of Swa2 in [URE3] propagation, and we propose a new model for plausible Swa2-Hsp90 cooperation in [URE3] prion propagation. [HSP90, URE3] (Mus musculus) PubMed

 20396.

Combination of neuroprotective factors Pedf plus docosahexaenoic acid (DHA) stimulates corneal nerve regeneration. Data suggest activation of Pedfr by Pedf (here, applied topically to treat corneal nerve injury) promotes regeneration of corneal nerve via up-regulation of release of DHA (here, also applied topically) and expression of specific nerve tissue/eye proteins. [Pedfr, pigment epithelium-derived factor receptor] (Mus musculus) PubMed

 20397.

Data suggest that transcription-coupled repair (TCR) is mediated by mfd translocase (but not uvrD, relA, or spoT); mfd mutation abolishes TCR genome-wide and in lacZ operon. [mfd = transcription-repair coupling factor mfd; uvrD = DNA helicase uvrD; relA = ppGpp synthetase; spoT = ppGpp pyrophosphorylase; ppGpp = guanosine pentaphosphate) [mfd, transcription-repair coupling factor mfd] (Mus musculus) PubMed

 20398.

Data suggest that at low pH KatG can fully convert H2O2 to O2 and H2O only if peroxidatic electron donors (PxEDs) are present in reaction; active-site tryptophan, Trp321, participates in "off-pathway" electron transfer; PxEDs stimulate KatG catalase activity by preventing accumulation of inactive intermediates. ATBS [2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid] is example of PxED. [KatG, catalase-peroxidase] (Mus musculus) PubMed

 20399.

OsPAP10c encodes a novel secreted APase that plays an important role in the utilization of external organic P in rice. (Mus musculus) PubMed

 20400.

down-regulated by abscisic acid in heat stress [miR-159b] (Mus musculus) PubMed

 20401.

exoribonuclease activity of nasp14 appears to block or correct the restriction of MHV infection by an IFN-mediated mechanism that may involve damaging nascent viral RNA and affecting subsequent infectivity[nsp14] (Mus musculus) PubMed

 20402.

MOTS-c has been shown to target the skeletal muscle and enhance glucose metabolism. As such, MOTS-c has implications in the regulation of obesity, diabetes, exercise, and longevity, representing an entirely novel mitochondrial signaling mechanism to regulate metabolism within and between cells. [REVIEW] (Mus musculus) PubMed

 20403.

All three Nt(t)PMP3-2 splice variants show increased root-specific expression. Implications of Nt(t)PMP3-2 alternative splicing on transcript stability and ORF features are discussed. (Mus musculus) PubMed

 20404.

LytF, a competence-controlled murein hydrolase, is capable of inducing the release of extracellular DNA (eDNA) from oral bacteria. Larger amounts of eDNA were released from cultures treated with protein samples containing LytF. Additionally, LytF could affect biofilm formation and cellular morphology. [LytF] (Mus musculus) PubMed

 20405.

One mechanism by which E. coli DNA polymerase I checks for Watson-Crick geometry is through a hydrogen bonding fork between Arg668 and the incoming dNTP and the minor groove of the primer terminus. This study shows that the active site interactions impact phosphoryl transfer during replication of damaged and undamaged DNA by escherichia coli DNA Polymerase I. [DNA Polymerase I] (Mus musculus) PubMed

 20406.

crystal structure of PatB1 (Mus musculus) PubMed

 20407.

Small RNA SmelC759 participates in RirA- and Irr-mediated regulation of bfr expression. [SmelC759] (Mus musculus) PubMed

 20408.

Growth of a hemP deletant was severely impaired in a medium containing hemin as the sole iron source, demonstrating the important role of HemP in hemin utilization. [Hemp] (Mus musculus) PubMed

 20409.

IutB participates in the ferric-vulnibactin utilization system in Vibrio vulnificus M2799. [IutB] (Mus musculus) PubMed

 20410.

Oct1p processing of Coq5p as an essential post-translational event for proper coenzyme Q production. (Mus musculus) PubMed

 20411.

MiG1 determines the size of cortical root cells. Expression peaks in arbuscule-containing cells, suggesting a role in cell remodeling during fungal accommodation. Roots ectopically expressing MIG1 become thicker due to an increase in the number and width of cortical cells. [MIG1] (Mus musculus) PubMed

 20412.

Together these data suggest a homeostatic feedback loop in which auxin up-regulates SL synthesis in an RMS2-dependent manner and SL down-regulates auxin synthesis in an RMS3 and RMS4-dependent manner. (Mus musculus) PubMed

 20413.

Purification and characterization of the colicin A immunity protein in detergent micelles.The NMR spectra were affected by the solubility, monodispersity, fold and dynamics of the protein-detergent complexes, and none of those tested here provided NMR spectra of sufficient quality to allow for peak assignment. [Colicin A immunity protein, E.coli] (Mus musculus) PubMed

 20414.

The deglycosylation of FcXTH1 by PNGase-F treatment affects its biochemical properties (increase KM and reduce kcat/KM ratio) and reduces its stability. As a conclusion, glycosylation of FcXTH1 is important for its biological function. (Mus musculus) PubMed

 20415.

EBV-miR-BART11 plays a crucial role in the promotion of inflammation-induced nasopharyngeal carcinoma (NPC) and gastric cancer (GC) carcinogenesis by directly targeting and inhibiting FOXP1 tumor-suppressive effects: [miR-BART11] (Mus musculus) PubMed

 20416.

Hel308/HelQ: WHD domain may contribute to ssDNA translocation, resulting in DNA helicase activity or in removal of other DNA bound proteins by "reeling" ssDNA. (Mus musculus) PubMed

 20417.

GlnE deletion mutant can grow diazotrophically at rates comparable to those of the wild type. (Mus musculus) PubMed

 20418.

Here, we describe how ATG8 can be used to monitor autophagy in Chlamydomonas and Arabidopsis by western blot analysis (Mus musculus) PubMed

 20419.

UDG: SMUG1-like DNA glycosylase from Listeria innocua was characterized. This enzyme is a single-stranded UDG with little activity on double-stranded uracil-containing DNA. Mutational analysis indicates similar roles of active site residues corresponding to SMUG1. (Mus musculus) PubMed

 20420.

Three novel bacterial alpha-l-fucosidases of Emticicia oligotrophica and their biochemical characterization and transfucosylation potential have been reported. [alpha-l-fucosidase] (Mus musculus) PubMed

 20421.

Inhibition of S. aureus ClfA binding to endothelial cell alphaV beta3 by cilengitide prevents endothelial dysfunction [ClfA] (Mus musculus) PubMed

 20422.

MutS2: A molecular basis for the functions of HpMutS2 in DNA recombination and repair. DNA binding domain (SDB) was mapped to the linker region between ATPase domain and Smr domain. Further, SDB was defined as a sequence of 30- amino-acid-residues containing a "KPPKNKFKPPK" motif. (Mus musculus) PubMed

 20423.

This study found that human DNA Polymerase kappa is more tolerant to changes in the active site loop than E. coli DinB. [DinB] (Mus musculus) PubMed

 20424.

PhlH modulates 2,4-diacetylphloroglucinol levels by controlling the expression of 2,4-diacetylphloroglucinol hydrolase PhlG in response to 2,4-diacetylphloroglucinol and monoacetylphloroglucinol. [PhlH] (Mus musculus) PubMed

 20425.

Deletion of creD inhibited the glucose-induced endocytosis of MalP. [MalP] (Mus musculus) PubMed

 20426.

KHSV miR-K3 activates the GRK2/CXCR2/AKT axis inducing KSHV-induced angiogenesis and promoting KSHV latency. (Mus musculus) PubMed

 20427.

Our goal here was to fine-map one of these QTLs, Adip20 (formerly Adip5), on mouse chromosome 9. To that end, we analyzed the weight of the gonadal adipose depot from newly created congenic strains. Results from the sequential comparison method indicated at least four rather than one QTL; two of the QTLs were less than 0.5 Mb apart, with opposing directions of allelic effect [adip20] (Mus musculus) PubMed

 20428.

Study highlights the eye- and pineal gland-specific expression pattern of a Ly-6 superfamily gene lypge in early development of zebrafish. It also reveals that lypge exhibits rhythmic expression in zebrafish larvae after 4 dpf and may be involved in the temporary regulation of development of eye and brain in zebrafish embryos. [lypge] (Mus musculus) PubMed

 20429.

The planar lipid bilayer experiment revealed that activated Vip3Aa formed ion channels at pH5.0-8.0 but no current signals were detected at pH10.0, consistent with the observation from calcein release assay. The toxin formed ion channels with a diameter of 1.4nm at pH8.0 and pore size was gradually decreased when reducing the pH. Pore-forming activity is regulated by pH. (Mus musculus) PubMed

 20430.

TomO enhances the maintenance of germ stem cells (GSCs) by elevating Nanos (Nos) expression via its interaction with nos mRNA, ultimately leading to the restoration of germ cell production in Sxl mutant females that are otherwise without GSCs.[TomO] (Mus musculus) PubMed

 20431.

The overexpression of d-lactate dehydrogenase LdhA in the DeltaldhR mutant partially restored the formed aggregate size, suggesting a role for fermentation inside aggregates. [LdhA, LdhR] (Mus musculus) PubMed

 20432.

Phosphoketolase role in carbon metabolism [Phosphoketolase] (Mus musculus) PubMed

 20433.

Mir396 regulates GRF4. Mir396 role in the grain size and yield.[Mir396] (Mus musculus) PubMed

 20434.

Mir-396 role in rice yield and shaping inflorescence architecture. [Mir-396] GRF6 role in rice yield and shaping inflorescence architecture. [GRF6] (Mus musculus) PubMed

 20435.

Transgenic plants highly expressing OsPCS1 showed significantly lower As levels in grains than did wild-type plants. The results provide new knowledge of the relative contribution of rice PCS paralogs to As sequestration and suggest a good candidate tool to reduce As levels in rice grains. [PCS1] (Mus musculus) PubMed

 20436.

The findings identify the otubain-like protease WTG1 to be an important factor that determines grain size and shape, suggesting that WTG1 has the potential to improve grain size and shape in rice. [WTG1] (Mus musculus) PubMed

 20437.

TrkJ is involved in the repression of kdpFABC in response to high external K(+) concentrations. [TrkJ, kdpF,kdpA, kdpB, kdpC] (Mus musculus) PubMed

 20438.

In this study, a novel NDM variant, NDM-17, was identified in a ST48 E. coli strain isolated from a chicken. The gene encoding NDM-17 was located on an IncX3 plasmid, which was readily transferrable to recipient E. coli strain J53 by conjugation, suggesting the possibility of the rapid dissemination of blaNDM-17 Enzyme kinetics showed that NDM-17 could hydrolyze all beta-lactams tested, except for aztreonam. [blaNDM-17] (Mus musculus) PubMed

 20439.

study concludes that a regulatory link between pseudomonas quinolone signal (PQS) and vqsR exists, and that RpoS is important in their interaction; also demonstrate that VqsR affects carbapenem tolerance [VqsR] (Mus musculus) PubMed

 20440.

Finally, Chlamydia trachomatis infection interferes with the SNX5:cation-independent mannose-6-phosphate receptor interaction, suggesting that Chlamydia IncE and cation-independent mannose-6-phosphate receptor are dependent on the same binding surface on SNX5.[IncE] (Mus musculus) PubMed

 20441.

Overexpressed Peroxiredoxin 2 (PRX2) causes the stomatal closing and K(+)-deficiency tolerance increasing, while knockout of PRX2 lead to serious defects in leaves phenotype and the stomatal opening under the K(+)-deficiency tolerance. [PRX2] (Mus musculus) PubMed

 20442.

Deletion of UGT1 resulted in growth and mating defects along with altered capsule and cellular morphology. The mutant was also phagocytosed more readily by macrophages than wild-type cells and cleared more quickly in vivo and in vitro, suggesting a mechanism for the lack of virulence observed in mouse models of infection. (Mus musculus) PubMed

 20443.

One elite transgenic rice line, BtE15, was identified with Cry2AX1 expression ranging from 0.68 to 1.34 microg g(-1) leaf fresh weight and with 80-92 % levels of resistance against rice pests at the vegetative and reproductive stages. Increase in Cry2AX1 protein concentration was also observed with crop maturity (Mus musculus) PubMed

 20444.

sequence analysis of the hypervariable region - [hmtp210] (Mus musculus) PubMed

 20445.

The C-terminal segment of coliphage HK022 Nun interacts with the RNA polymerase beta and beta' subunits inside the RNA polymerase active site cleft as well as with nearly every element of the nucleic acid scaffold, essentially crosslinking the RNA polymerase and the nucleic acids to prevent translocation.[Nun] (Mus musculus) PubMed

 20446.

WblA plays a key role in control of daptomycin biosynthesis and is essential for sporulation. [WblA] (Mus musculus) PubMed

 20447.

Association analysis and in silico sequence domain annotation support TXNRD3 polymorphisms as candidate to regulate ALDBSSCG0000001928 expression, which can be involved in the transcriptional regulation of surrounding genes, affecting productive and meat quality traits. (Mus musculus) PubMed

 20448.

Previous study identified rice depressed palea1 (dp1) mutants with defects in main structure of palea and its enhancer RETARDED PALEA1 (REP1). DP1 is an AT-hook protein while REP1 is a TCP transcription factor, both of which are important regulators of palea development. DP1 interacts physically with REP1 both in rice protoplasts. [DP1, REP1] (Mus musculus) PubMed

 20449.

Using these screens and immunoblot measures of Tf1 proteins, we identified a total of 61 genes that promote integration. Two candidates, Rhp18 and the NineTeen complex were tested in two-hybrid assays and were found to interact with Tf1 IN. (Mus musculus) PubMed

 20450.

These calculations demonstrate that the structure and biophysical properties of a correctly assembled c-subunit ring of the F1Fo ATP synthase are inconsistent with those attributed to the mitochondrial permeability transition pore.[F1Fo ATP synthase c-subunit] (Mus musculus) PubMed

 20451.

This study demonstrates that the expression of apoplast-targeted plant defensin MtDEF4.2 from Medicago truncatula can provide substantial resistance to an economically important leaf rust disease in transgenic wheat without negatively impacting its symbiotic relationship with the beneficial mycorrhizal fungus. (Mus musculus) PubMed

 20452.

Authors used 2 strategies to characterize the HDAC8 interactome and found HDAC8 partners are involved in about 40 different processes, included expected functions such as the cohesin complex, cytoskeleton organization, transcriptional and translational regulation, metabolism, DNA repair, the cell cycle, protein dephosphorylation, proteolysis, protein transport, and some proteasome & ribosome components. [HDAC8] (Mus musculus) PubMed

 20453.

herefore, disruption of all genes whose products localize to the endoplasmic reticulum (ER) or have an unknown location did not obliterate UDP-Glc ER entrance. We conclude that the hut1(+) gene product is involved in UDP-Glc entrance into the ER, but that at least another as yet unknown NST displaying an unconventional sequence operates in the yeast secretory pathway. (Mus musculus) PubMed

 20454.

The Chlamydia trachomatis IncE binding site is unique to human SNX5 and related family members SNX6 and SNX32.[IncE] (Mus musculus) PubMed

 20455.

The authors identified the apoptosis regulator Mcl-1 as a target that interacts with Chlamydia trachomatis Cdu1 and is stabilized by deubiquitination at the chlamydial inclusion.[Cdu1] (Mus musculus) PubMed

 20456.

TaTAR2.1 is critical for wheat growth and also shows potential for genetic engineering to reach the aim of improving the grain yield of wheat.TaTAR2.1] (Mus musculus) PubMed

 20457.

In stomata, loss of OsK5.2 functional expression resulted in lack of time-dependent outward potassium currents in guard cells, higher rates of water loss through transpiration, and severe slowdown of stomatal closure.[OsK5.2] (Mus musculus) PubMed

 20458.

NOS is crucial for the S. aureus heme stress response. [NOS] (Mus musculus) PubMed

 20459.

TaVIT2, but not TaVIT1, was able to rescue the growth of a yeast (Saccharomyces cerevisiae) mutant defective in vacuolar iron transport. TaVIT2 also complemented a manganese transporter mutant but not a vacuolar zinc transporter mutant.[TaVIT2] (Mus musculus) PubMed

 20460.

Only a disruption of malK3 produced a defect in maltose catabolism. [MalK3] (Mus musculus) PubMed

 20461.

Data suggest that capsid of Rosellinia necatrix quadrivirus 1 is built of P2 and P4 protein heterodimers, each with more than 1000 residues; despite a lack of sequence similarity between P2 and P4, they have similar alpha-helical domains; domain insertions in P2/P4 preferential sites provide additional functions at capsid outer surface, probably related to enzyme activity. [P2, capsid protein 2; P4, capsid protein 4] (Mus musculus) PubMed

 20462.

alpha2-chimaerin, is a critical negative regulator of Rac1 in hippocampal neurons. The loss of alpha2-chimaerin significantly increases the levels of active Rac1 and induces the formation of aberrant polymorphic dendritic spines. (Mus musculus) PubMed

 20463.

two major CAD isoforms, SbCAD2 (Brown midrib 6 [bmr6]) and SbCAD4, in lignifying tissues of sorghum (Sorghum bicolor), indicates their similarity in both structure and activity to Arabidopsis (Arabidopsis thaliana) CAD5 and Populus tremuloides sinapyl alcohol dehydrogenase, respectively.[CAD4] (Mus musculus) PubMed

 20464.

The PilZ domain of MrkH represents a novel DNA binding motif. (Mus musculus) PubMed

 20465.

An extensive molecular dynamics simulation on the crystallographic structure of the homodimeric B. subtilis GabR has been undertaken with the aim to envisage the role and the importance of conformational flexibility in the action of GabR.[GabR] (Mus musculus) PubMed

 20466.

an indirect role of the EKI tripeptide in CaMV plant-to-plant propagation, is reported.[TAV] (Mus musculus) PubMed

 20467.

nicotinamide can act as a CobB regulator in vivo [cobB] (Mus musculus) PubMed

 20468.

mechanical properties of MscL alpha helices [MscL] (Mus musculus) PubMed

 20469.

mechanical properties of MscL alpha helices [MscL] (Mus musculus) PubMed

 20470.

Med15B regulates tolerance toward low pH via transcriptional regulation of acid stress response genes and alteration in lipid composition. [med15B] (Mus musculus) PubMed

 20471.

presence of the D, I, Q and N at position 58, 60, 62 and 122 in cagL respectively increased the risk of peptic ulcer. However,amino acid N, M, Q and N at the same position alongside V134 increased the risk of gastric cancer (cagL protein). (Mus musculus) PubMed

 20472.

these data support a model in which RDN1 arabinosylates MtCLE12, and this modification is necessary for the transport and/or reception of the AON signal by the SUNN kinase.[RDN1, CLE12, CLE13, SUNN] (Mus musculus) PubMed

 20473.

the Drosophila Trpa1 channel and the evf virulence factor are being necessary for the food intake decrease [TRpa1] (Mus musculus) PubMed

 20474.

Taken together, these findings identify leishmania chaperonin 10 as a novel effector with broad based effects on macrophage cell regulation and parasite survival.[chaperonin 10] (Mus musculus) PubMed

 20475.

Gcn4 also acts as a repressor of protein biosynthesis in a range of conditions that enhance yeast lifespan.[Gcn4] (Mus musculus) PubMed

 20476.

The accessory gene regulator (Agr) is known to inhibit biofilm formation by up-regulating extracellular proteases, an important contributor to the dispersal of established biofilm . Inhibitory effect of ClpP on biofilm formation is through Agr and the cell wall hydrolase Sle1. (Mus musculus) PubMed

 20477.

the ABA-responsive transcription factor MdAREB2 directly activates the expression of amylase and sugar transporter genes.[MdAREB2] (Mus musculus) PubMed

 20478.

integrin alpha4beta1 mediates the inhibitory effect of oncofetal Fibronectin both in vitro as well as in vivo.[Oncofetal fibronectin] (Mus musculus) PubMed

 20479.

To gain mechanistic insights into the role that TslA plays in cell wall homeostasis, immunoprecipitation assays coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) were used to reveal a direct interaction between TslA and CsmA, a type V chitin synthase enzyme.[TslA, CsmA] (Mus musculus) PubMed

 20480.

Our results demonstrate a wide distribution of Tir-cytoskeleton coupling protein tccP/tccP2 genes among pathogenic atypical enteropathogenic Escherichia coli strains, as well associations between specific alleles and phylogenetic backgrounds. [TccP; TccP2] (Mus musculus) PubMed

 20481.

These results provide new insights into the effects of the ubiquitination system mediated by TaGW2-6A on the Gibberellins (GA) hormone signaling pathway, thereby improving our understanding of the role of TaGW2-6A in seed development in wheat. [TaGW2-6A] (Mus musculus) PubMed

 20482.

besides dephosphorylation of cellular organic Phosphorus, OsHAD1 in coordination with kinases may regulate the phosphorylation status of downstream targets to accomplish inorganic phosphorus (Pi) homeostasis under limited Pi supply.[OsHAD1] (Mus musculus) PubMed

 20483.

Msf1 is required for the maintenance of photosystem I and specific protein-chlorophyll complexes especially under certain stress conditions.[Msf1] (Mus musculus) PubMed

 20484.

functional importance of autophosphorylation in NtCDPK1, was investigated.[NtCDPK1] (Mus musculus) PubMed

 20485.

StcE reduced the inner mucus layer and thereby promoted Enterohaemorrhagic Escherichia coli access and binding to the epithelium in vitro and ex vivo (Mus musculus) PubMed

 20486.

These results revealed a key role of the miR390/TAS3 pathway in legumes as a modulator of lateral root organs, playing opposite roles in lateral root and nodule development.[miR390, TAS3] (Mus musculus) PubMed

 20487.

Study identified three catalytic site in LytB, namely SH3b, WW, and GH73. Molecular docking of a putative tetrasaccharide-pentapeptide substrate which seems to be well accommodated in a T-shaped substrate binding pocket formed by the three modules. [LytB] (Mus musculus) PubMed

 20488.

These lines of evidence strongly suggest that the FtlA lipase promotes F. tularensis adhesion and internalization by modifying bacterial and/or host molecule(s) when it is secreted as a component of outer membrane vesicles [FtlA] (Mus musculus) PubMed

 20489.

SsFkh1 is involved in hyphal growth, virulence and sclerotial formation in S. sclerotiorum. (Mus musculus) PubMed

 20490.

Mg(2+) transported by OsMGT1 in the root mature zone is required for enhancing OsHKT1;5 activity, thereby restricting Na accumulation to the shoots.[OsMGT1] (Mus musculus) PubMed

 20491.

The identification and characterization of the OsQUA2 gene and its functionality revealed a previously unknown contribution of Homogalacturonan methylesterification.[OsQUA2] (Mus musculus) PubMed

 20492.

C. reinhardtii Flv participates in a Mehler-like reduction of O2, which drives a large part of the photosynthetic electron flow during a light transient and is thus critical for growth under fluctuating light regimes.[FlvA, FlvB] (Mus musculus) PubMed

 20493.

The results reveal that SHP1 is the long-sought phosphatase that can antagonize Helicobacter pylori CagA. Augmented Helicobacter pylori CagA activity, via SHP1 inhibition, might also contribute to the development of Epstein-Barr virus-positive gastric cancer. (Mus musculus) PubMed

 20494.

CRY1 acts as the major enzyme of light-driven DNA repair (photoreactivation) and CRY2 is dispensable for photorepair but performs regulatory functions by repressing conidiation in white and especially black/NUV light. [Cry1, Cry2] (Mus musculus) PubMed

 20495.

the individual and combined contributions of the three MAPKs Fmk1, Mpk1 and Hog1 in the regulation of development, stress response and virulence of F. oxysporum on plant and animal hosts, is reported.[Fmk1, Mpk1, Hog1] (Mus musculus) PubMed

 20496.

The purified recombinant SlugATIC and its truncated domains exist mainly in dimeric form. The 2 activities reside on separate domains. Lys255 and His256 are the key catalytic residues, while Asn415 substantially contributes to AICAR TFase activity. There are significant conformational changes on leading-ligand binding to AICAR TFase domain.It promotes cell proliferation and viability. ATIC. (Mus musculus) PubMed

 20497.

RegA is a key regulator of Brucella suis in adaptation to oxygen depletion. [RegA] (Mus musculus) PubMed

 20498.

Because PfEMP1 and Pf332 also bind to actin and/or spectrin, the authors propose that the interaction between tryptophan-rich domains (WRD) and red blood cell (RBC) membrane skeleton might be a common feature of WRD-containing proteins and may be important for the translocation of these proteins from Maurer's clefts to the iRBC surface. [SURFIN4.2] (Mus musculus) PubMed

 20499.

Because PfEMP1 and Pf332 also bind to actin and/or spectrin, the authors propose that the interaction between tryptophan-rich domains (WRD) and red blood cell (RBC) membrane skeleton might be a common feature of WRD-containing proteins and may be important for the translocation of these proteins from Maurer's clefts to the iRBC surface. [STP2] (Mus musculus) PubMed

 20500.

The acceleration of flowering by NB disappeared in ppd1-null mutants, demonstrating that this response is mediated by PPD1.[PPD1] (Mus musculus) PubMed

 20501.

Data show that miR-K12-11 transfers in vitro from Kaposi's sarcoma herpesvirus (KSHV)-infected BCBL-1 and BC-1 lymphoma cell lines to T cells: [miR-K12-11] (Mus musculus) PubMed

 20502.

TaSPL20 and TaSPL21 homoeologs underwent diversification in function with each evolving its own distinctive characteristics.[TaSPL20, TaSPL21] (Mus musculus) PubMed

 20503.

results indicate that two plasmids, pIBB477a and b, are involved in adhesion of the IBB477 strain. One of the genes localised on plasmid pIBB477b (AJ89_14230), which encodes cell wall-associated peptidase S8 (PrtP), mediates adhesion of the IBB477 strain to bare, mucin- and fibronectin-coated polystyrene, as well as to HT29-MTX cells [peptidase S8 (PrtP)]. (Mus musculus) PubMed

 20504.

The RNAi knock-down of Trypanosoma brucei GSK3beta reduced Tf endocytosis. [GSK3beta] (Mus musculus) PubMed

 20505.

These findings reveal a new molecular mechanism for plant growth and leaf senescence mediated by PECTATE LYASE-LIKE genes.[PECTATE LYASE-LIKE] (Mus musculus) PubMed

 20506.

DCL4 imposed an epistatic effect on DCL2 to impede cell-to-cell spread of virus-induced RNA silencing.[DCL2, DCL4] (Mus musculus) PubMed

 20507.

study identified a serralysin-like protease in the genome of a clinical isolate of Serratia marcescens that is highly similar to the canonical serralysin protein, PrtS. This gene was named serralysin-like protease E, SlpE, and was found in the majority of tested clinical isolates but was absent from most tested non-clinical isolates[SlpE] (Mus musculus) PubMed

 20508.

Results confirmed the function of gene XC_0531, which encodes a DsbD like protein, a protein correlated with c-type cytochrome biogenesis. This gene is related to the virulence to plants by affecting funtion of cytochromes c and probably disulfide bonds modification of proteins in type II secretion system (T2SS). [XC_0531] (Mus musculus) PubMed

 20509.

The full-length cgRPL29 cDNA of the Pacific oyster comprised 325-bp, including a 5'-untranslated region (UTR) of 100-bp, a 3'-UTR of 57-bp, and an open reading frame of 168-bp encoding 55 amino acids, with a Met residue at the N-terminus. [RPL29] (Mus musculus) PubMed

 20510.

Virtually Designed Triclosan-Based Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis and of Plasmodium falciparum. (Mus musculus) PubMed

 20511.

Cwp19 has a TIM barrel fold and appears to possess a high degree of substrate selectivity. The protein also exhibits peptidoglycan hydrolase activity, an order of magnitude slower than that of lysozyme and is the first member of glycoside hydrolase-like family 10 to be characterised. Cwp19. (Mus musculus) PubMed

 20512.

The OtsA:R328H substitution promotes both intra- and extracellular trehalose accumulation. Build-up of intracellular trehalose accounts for the OtsA(R)(328H) -dependent thermotolerance. Wild-type OtsA overexpression counteracts the trehalose-dependent regulation and restores the evolved strain-like phenotype to the isogenic wild-type otsA revertant, so the mutant's thermotolerance is due to its feedback-resistance. OTSa. (Mus musculus) PubMed

 20513.

RPA4515 binds aliphatic dicarboxylates of a chain length of six to nine carbons.Crystal structures of AdpC, either adipate or 2-oxoadipate bound, revealed a lack of positively charged amino acids in the binding pocket and showed that water molecules are involved in bridging hydrogen bonds to the substrate. Expression is upregulated by low environmental adipate. Its role may be in signalling rather than transport. AdpC. (Mus musculus) PubMed

 20514.

NirJ is a Radical SAM enzyme carrying 2 iron-sulfur clusters. The N-terminal [4Fe-4S] cluster is essential for the initial SAM cleavage reaction, but it is not required for substrate binding.NirJ indeed catalyzes the removal of the 2 propionate side chains under simultaneous SAM cleavage. Under these reaction conditions, no keto group formation is observed, so an additional cofactor or enzyme may be needed. (NirJ). (Mus musculus) PubMed

 20515.

FlgE2 is composed of 3 distinct domains, 2 of them relatively similar to those of FlgE from other Gram-negative bacteria, whilst the 3d is peculiar to H. pylori. The crystal structure and a detected interaction with the regulatory cap protein FlgD suggest a complementary function of FlgE1 and FlgE2 in the flagellum, possibly typical of polar flagella, confirming the role of both proteins in the flagellar hook. (FlgE2). (Mus musculus) PubMed

 20516.

RgpG in S. mutans plays a critical role in cell division and biofilm formation and that BrpA and Psr may be responsible for attachment of cell wall antigens to the cell envelope. [Psr] (Mus musculus) PubMed

 20517.

Due to its beta-N-acetylglucosaminidase activity, W-Chi22718 was able to produce N-acetyl-D-glucosamine (GlcNAc) monomers from chitin oligosaccharide substrates. [beta-N-acetylglucosaminidase] (Mus musculus) PubMed

 20518.

This study strongly supports the conclusion that pde1 is essential for virulence and additionally shows variation to be important in specific regions of pde1. [pde1] (Mus musculus) PubMed

 20519.

a series of conventional and hybrid quantum mechanics/molecular mechanics (QM/MM) molecular dynamics simulations of the Staphylococcus aureus sortase A (SrtA) enzyme bound to a sorting signal substrate, are reported.[Sortase A] (Mus musculus) PubMed

 20520.

NdbC has a significant function in regulating carbon allocation between storage and the biosynthesis pathways.[Ndbc] (Mus musculus) PubMed

 20521.

VPS15 regulates the distribution of the 100-300 nm organelles that contain the major eisosome protein Pil1p to the extracellular fraction.[Vps15, Pil1] (Mus musculus) PubMed

 20522.

CobB suppressed acetylation to lower than median stoichiometry in WT, ptaDelta, and ackADelta cells.[CobB] (Mus musculus) PubMed

 20523.

animal-like CRY is differentially expressed not only during the life cycle but also within the cell as part of the soluble and/or membrane-associated protein fraction.[aCRY] (Mus musculus) PubMed

 20524.

Results revealed that Y125, Y365, and Y541 were essential to the function of KsdD and that Y122, S138 and E140 contributed to its catalysis function. [KsdD] (Mus musculus) PubMed

 20525.

identified a gene, ptsI, which positively regulates transcription of sodA2;. ptsI encodes Enzyme I of the phosphotransferase system (PTS); results suggest that the PTS plays an important role in rhizosphere colonization by both promoting nutrient utilization and regulating sodA2 expression in B. cereus 905 [ptsI, sodA2] (Mus musculus) PubMed

 20526.

These results indicate that the dynamic rearrangement of actin higher structures involving GhFIM2 plays an important role in the development of cotton fiber cells.[GhFIM2] (Mus musculus) PubMed

 20527.

Deletion analyses demonstrated that although its N-terminal variable domain plays an essential role in optimizing Ca(2+)-dependent RcCDPK1 autophosphorylation and BTPC transphosphorylation activity, it is not critical for in vitro or in vivo target recognition.[RcCDPK1] (Mus musculus) PubMed

 20528.

plant eIF4G binds to eIF4E through both the canonical and noncanonical motifs, similarly to metazoan eIF4E-eIF4G complexes.[eIF4E, eIF4G] (Mus musculus) PubMed

 20529.

OsCUL3a negatively regulates cell death and immunity by degrading OsNPR1 in rice. (Mus musculus) PubMed

 20530.

Authors identify two novel alleles of Lotus japonicus REDUCED ARBUSCULAR MYCORRHIZA1 (RAM1) encoding a GRAS protein; confirm that RAM1 is a central regulator of arbuscule development: arbuscule branching is arrested in L. japonicus ram1 mutants, and ectopic expression of RAM1 activates genes critical for arbuscule development in the absence of fungal symbionts. [RAM1] (Mus musculus) PubMed

 20531.

review of the recent developments in understanding of CtHtrA's physiological role in Chlamydia focuses on the CtHtrA characteristics that make it unique from other bacterial HtrAs and an ideal target for drug development [HTtrA] (Mus musculus) PubMed

 20532.

Characterization of rice Osgi and Ospho2 mutants revealed that they displayed several similar phenotypic features supporting a physiological role for this interaction.[Gi, Pho2] (Mus musculus) PubMed

 20533.

CaMYB31 is indeed involved in the regulation of structural genes of the capsaicinoid biosynthetic pathway.[CaMYB31] (Mus musculus) PubMed

 20534.

UNG: Uracil excision by bacterial UDG and human hUNG2 is reduced at uracils positioned directly 5' or 3' of a G-quadruplex DNA structures. (Mus musculus) PubMed

 20535.

MoYcp4, a target of MoAP1, is involved in the growth, conidiogenesis and pathogenicity of M. oryzae.[MoYcp4] (Mus musculus) PubMed

 20536.

genomic and cDNA of beta-glucosidase 1 (BGL1) were isolated from Trichoderma virens and successfully characterized in S.cerevisiae. The major ligand binding domain was identified and indicates an overall stable confirmation of BGL-cellobiose complex that exhibits a similar structural flexibility shown by the free enzyme with mainly five hydrogen bonds in maintaining the enzyme-substrate association. [BGL1] (Mus musculus) PubMed

 20537.

results showed an up-regulation of septum site determining gene (ssd) - MT3760 during stationary phase and starvation conditions, but not during in vitro dormancy, suggesting a putative role for SigD in the control of ssd expression mainly under lack-of-nutrients environments [MT3760, SigD] (Mus musculus) PubMed

 20538.

expression of two genes TEOSINTE BRANCHED1 (TaTB1) and BARREN STALK1 (TaBA1), whose orthologous genes in diverse plant species play conserved roles in regulating plant architecture, is markedly reduced in the tae-miR156-Overexpressed bread wheat plants.[miR156, DWARF53, TB1, BA1, SPL3/17] (Mus musculus) PubMed

 20539.

The bile salt deoxycholate enhanced Shigella virulence is regulated by the pi-Helix in the IpaD protein. [ IpaD ] (Mus musculus) PubMed

 20540.

Surprisingly we also find that Aurora inactivation leads to cellular swelling and lysis indicating an unexpected function for Aurora in fungal cell growth. Thus in addition to its conserved mitotic functions our data suggest that Aurora has the capacity to be an important regulator of septal biology and cell growth in filamentous fungi (Mus musculus) PubMed

 20541.

Bg_9562 is essential for mycophagy in Burkholderia gladioli and is translocated into fungal mycelia during confrontation.[Bg_9562 ] (Mus musculus) PubMed

 20542.

The essential role of CysK in contact-dependent growth inhibition of toxin activation in uropathogenic Escherichia coli 536 has been described. [CysK] (Mus musculus) PubMed

 20543.

Thylakoid luminal theta-carbonic anhydrase critical for growth and photosynthesis in the marine diatom Phaeodactylum tricornutum has been reported. [theta-carbonic anhydrase] (Mus musculus) PubMed

 20544.

Data suggest a role for the intrinsically disordered C-terminal linker (CTL) region of FtsZ in regulating polymer structure and dynamics in vitro; FtsZ lacking its CTL region exhibits dramatically increased propensity to form long multifilament bundles compared with wild type. [FtsZ, cell division protein FtsZ] (Mus musculus) PubMed

 20545.

We discover that directional proliferation of rod-shaped bacteria plays a dominant role in shaping the biofilm architecture in V. cholerae biofilms, and this growth pattern is controlled by a single gene, rbmA Competition analyses reveal that the dense growth mode has the advantage of providing the biofilm with superior mechanical properties. (Mus musculus) PubMed

 20546.

Data suggest that Brucella melitensis effector protein TcpB suppresses caspase-4/11--mediated inflammation, subverting inflammasome activation in mouse macrophages; TcpB induces ubiquitination/degradation of caspase-4/11; TcpB suppresses caspase-4/11--mediated pyroptosis and proinflammatory responses induced by lipopolysaccharide. [TcpB, effector protein TcpB] (Mus musculus) PubMed

 20547.

Recombinant OmpU (rOmpU) of V. cholerae induced IL-8 expression at the mRNA and protein levels in a dose- and time-dependent manner ini HT-29 cells. This was mediated via ERK1/2 and p38 kinase pathways, but not via JNK signaling pathway. [OmpU] (Mus musculus) PubMed

 20548.

NtDRP is involved in orientation of the asymmetric zygotic division and differentiation of distinct suspensor and embryo domains, as well as subsequent embryo pattern formation.[NtDRP] (Mus musculus) PubMed

 20549.

Ppn2 is responsible for a substantial fraction of polyphosphatase activity that is necessary to mobilize polyPhosphate stores, for example in response to phosphate scarcity.[Ppn2] (Mus musculus) PubMed

 20550.

OsCOLE1 affects rice development by regulating intracellular auxin transport through interaction with OsCLIP.[OsCOLE1, OsCLIP] (Mus musculus) PubMed

 20551.

These data suggest that IFT52 and IFT46 can preassemble as a complex in the cytoplasm, which is then targeted to basal bodies.[IFT46] (Mus musculus) PubMed

 20552.

Data suggest that MinE-membrane interactions induce structural change to state resembling open conformation; binding of MinE to MinD is sufficient to trigger conformational transition in MinE; conformational change between open/closed states does not affect ATP hydrolysis rates in absence of membrane binding. [MinE, cell division topological specificity factor MinE; MinD, septum site-determining protein/ATPase MinD] (Mus musculus) PubMed

 20553.

SYNTAXIN OF PLANTS 13II (SYP13II) is a t-SNARE that is essential for the formation of a stable symbiotic interface in both Arbuscular mycorrhiza and rhizobium symbiosis.[SYP13II] (Mus musculus) PubMed

 20554.

Dynamic changes in GhSFT and GhSP levels navigate meristems between monopodial and sympodial programs in a single plant.[GhSFT, SP] (Mus musculus) PubMed

 20555.

Combining these data with previous reports, the authors suggested a dynamic interaction mechanism in KaiA-KaiC interaction, in which both KaiA and the intrinsically disordered tail of KaiC undergo significant structural changes through conformational selection and induced fit during the binding process.[KaiA, KaiC] (Mus musculus) PubMed

 20556.

Thus, Aspergillus fumigatus CalA is an invasin that interacts with integrin alpha5beta1 on host cells, induces endocytosis and enhances virulence.[CalA] (Mus musculus) PubMed

 20557.

We propose that DUS16 is an essential factor for miRNA production in Chlamydomonas and, because DUS16 is functionally similar to the dsRNA-binding proteins involved in miRNA biogenesis in animals and land plants, our report provides insight into this mechanism in unicellular eukaryotes. (Mus musculus) PubMed

 20558.

Leishmania constitutive Ca(2+)/calmodulin-dependent nitric oxide synthase is involved in the parasite cell death. These data suggest activation of Leishmania nitric oxide synthase as a new therapeutic approach. (Mus musculus) PubMed

 20559.

These data demonstrate a positive role for NAD1 in the maintenance of rhizobial endosymbiosis during nodulation.[NAD1] (Mus musculus) PubMed

 20560.

This study presents the catalytic activity of BaAA10. It is a chitin-active lytic polysaccharide monooxygenase, active on both alpha and beta chitin, with the Cu(ii) binding with low nM KD, and the substrate greatly increasing the thermal stability of the enzyme. [BaAA10] (Mus musculus) PubMed

 20561.

Helicobacter pylori HopQ binds the amino-terminal IgV-like domain of human CEACAM1, CEACAM3, CEACAM5 or CEACAM6 proteins, thereby enabling translocation of the major pathogenicity factor CagA into host cells.[HopQ, CagA] (Mus musculus) PubMed

 20562.

Here, the authors identify members of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as receptors of Helicobacter pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1, CEACAM3, CEACAM5 and CEACAM6.[HopQ] (Mus musculus) PubMed

 20563.

The authors show that calcium stimulates the Gac/Rsm pathway via the Gac-associated hybrid histidine kinase LadS. They also show that calcium binds to the periplasmic DISMED2 sensor domain of LadS to activate its kinase activity.[LadS] (Mus musculus) PubMed

 20564.

PKA controls chemoattractant signal transduction, in part, through the regulation of RasG, Rap1 and TORC2.[PKA] (Mus musculus) PubMed

 20565.

study focused on verification of SgpR's involvement in regulation of transcription of the sgp operon genes for salicylate degradation through gentisate and characterization of SgpR interaction with the sgp promote [SgpR]. (Mus musculus) PubMed

 20566.

The RxDL motif was not required for MC160's ability to inhibit MAVS-induced IFNbeta activation. (Mus musculus) PubMed

 20567.

Data suggest that TE6 exhibits acyl-CoA thioesterase with substrate specificity including acetyl coenzyme A and various acyl coenzyme A; each enzyme subunit exhibits a hot dog-fold and subunits form a hexamer with D3 symmetry; six GDP bind to enzyme in close proximity to inter-subunit disulfide bonds that covalently link domains in a double hot dog dimer. [TE6, acyl-CoA thioesterase TE6] (Mus musculus) PubMed

 20568.

Staphylococcus aureus type VII protein secretion system secretes a large nuclease toxin, EsaD. The toxic activity of EsaD is neutralized during its biosynthesis through complex formation with an antitoxin, EsaG, that binds to the EsaD N-terminal region. The secretion of EsaD is dependent on a further accessory protein, EsaE, that binds to the EsaD N-terminal region.[EsaD, EsaG, EsaE] (Mus musculus) PubMed

 20569.

Data suggest FUS3 has role in driving cell fate decision (here, yeast mating response to pheromone); most cells in elongated growth show either delayed gradual increase or pulsatile dynamics of FUS3 activity; cells committed to growth arrest and shmoo formation exhibit sustained FUS3 activation. Cells derived from S. cerevisiae W303 were used in these studies. [FUS3, mitogen-activated serine/threonine-protein kinase FUS3] (Mus musculus) PubMed

 20570.

BnaC4.BOR1;1c is a AtBOR1-homologous B transporter gene expressing in both roots and shoot nodes that is essential for the developing inflorescence tissues.[BnaC4.BOR1;1c] (Mus musculus) PubMed

 20571.

These results indicate that CozE is a member of the MreCD complex of Streptococcus pneumoniae that directs the activity of PBP1a to the midcell plane where it promotes zonal cell elongation and normal morphology.[CozE] (Mus musculus) PubMed

 20572.

WASH drives protein sorting and recycling from macropinosomes and is thus essential to maintain surface receptor levels and sustain phagocytosis.[WASH] (Mus musculus) PubMed

 20573.

recognition of AT-rich DNA is not sufficient for the asymmetric accumulation of GapR.[GapR] (Mus musculus) PubMed

 20574.

the activity of l-DES, as well as the enzymes involved in nitrogen metabolism, was significantly increased in the OsSE5-overexpression line.[l-DES] (Mus musculus) PubMed

 20575.

ProQ is an abundant RNA-binding protein with a wide range of ligands and a global influence on Salmonella gene expression.[ProQ] (Mus musculus) PubMed

 20576.

The glycosyltransferase activity of PBP1A, which aids in the polymerization of the peptidoglycan cell wall, was lethal to LOS-deficient A. baumannii.[PBP1A] (Mus musculus) PubMed

 20577.

These findings establish PI5P4Kalpha as a kinase that synthesizes a physiologically relevant pool of PI(4,5)P2 and as a regulator of mTORC2, and show a phenomenon similar to the "butterfly effect" described for phosphatidylinositol 3-kinase Ialpha (Mus musculus) PubMed

 20578.

Here, the authors show that nitric oxide synthase (NOS) of the human pathogen Staphylococcus aureus, in concert with a nitric oxide-metabolizing flavohaemoprotein, regulates electron transfer by targeting haem-containing cytochrome oxidases under microaerobic conditions to maintain membrane bioenergetics.[NOS] (Mus musculus) PubMed

 20579.

the host-transcriptional alterations induced as a consequence of viroid-mediated HDA6 recruitment favor spurious recognition of Hop stunt viroid-RNA as an RNA Pol II template, thereby improving viroid replication.[HDA6] (Mus musculus) PubMed

 20580.

ChELP1 and ChELP2 are essential for fungal virulence and appressorium-mediated penetration of both Arabidopsis epidermal cells and cellophane membranes in vitro.[ChELP1, ChELP2] (Mus musculus) PubMed

 20581.

depleting eukaryotic translation initiation factor 4G (eIF4G), the scaffold subunit of eukaryotic translation initiation factor 4F (eIF4F), preferentially impacts short mRNAs with strong closed-loop potential and unstructured 5' UTRs, exactly the opposite features associated with hyperdependence on the eIF4B/helicases. (Mus musculus) PubMed

 20582.

Together, these data indicate that P31(comet) plays a key role in DSB formation and SC installation, mainly through its cooperation with CRC1. (Mus musculus) PubMed

 20583.

under conditions of oxygen deficiency, succinate accumulates mainly due to downregulation of SDH gene expression and reduction of enzyme activity, and to a lesser extent due to the decrease of fumarase gene expression.[SDH, Fumarase] (Mus musculus) PubMed

 20584.

the overexpression or knockdown of Jiv90 in swine cells can also significantly promote or decrease the viral load, respectively. (Mus musculus) PubMed

 20585.

Data, including data on structure of two mutant Rgg2 compared with wild-type Rgg2, suggest that, in the absence of intermolecular disulfide, Rgg2 dimer interface is destabilized and Rgg2 can adopt multiple conformations. [Rgg2, quorum-sensing regulator Rgg2] (Mus musculus) PubMed

 20586.

Fiber protein contained 512 amino acids encoded by S7 segment and functioned as the cell attachment protein in Grass carp reovirus. [Fiber protein] (Mus musculus) PubMed

 20587.

Depletion of NusA altered global gene expression directly and indirectly via readthrough of suboptimal terminators. Readthrough of NusA-dependent terminators caused misregulation of genes involved in essential cellular functions, especially DNA replication and metabolism.[NusA] (Mus musculus) PubMed

 20588.

Data suggest that Mid1, a regulatory subunit of Cch1, exhibits a 20-amino-acid-long N-terminal signal peptide and appears to be entirely localized extracellularly. These studies were conducted using S. cerevisiae parental strain H207. [Mid1, regulatory subunit of Cch1; Cch1, calcium channel protein Cch1] (Mus musculus) PubMed

 20589.

Vimentin and its interaction with Shigella flexneri IpaC are dispensable for effector translocation pore formation, but are required for stable docking of Shigella flexneri to cells; moreover, stable docking triggers effector secretion. (Mus musculus) PubMed

 20590.

The 12-transmembrane ClbM is characterized as a cation-coupled antiporter, and residues important to the cation-binding site are identified. The data identify ClbM as a precolibactin transporter and provide the first structure of a multidrug and toxic compound extrusion transporter with a defined and specific biological function.[ClbM] (Mus musculus) PubMed

 20591.

MiR-274-3p could facilitate BmCPV replication by up-regulating BmCPV NS5 gene expression.[Mir-247-3p] (Mus musculus) PubMed

 20592.

Study identified a gene, Musca domesticamale determiner (Mdmd), as the M-factor. Mdmd originated from a duplication of the spliceosomal factor gene CWC22 (nucampholin). Targeted Mdmd disruption results in complete sex reversal to fertile females because of a shift from male to female expression of the downstream genes transformer and doublesex. [Mdmd] (Mus musculus) PubMed

 20593.

The results identify BELL1 as a master regulator for the gametophyte-to-sporophyte transition in Physcomitrella patens and provide mechanistic insights into the evolution of embryos that can generate multicellular diploid sporophytes. [BELL1] (Mus musculus) PubMed

 20594.

this study contributes to the understanding of the AphB molecular mechanism in the process of recognizing the host environment. [AphB] (Mus musculus) PubMed

 20595.

pfcarl mutations confer resistance to two distinct compound classes, benzimidazolyl piperidines and imidazolopiperazines.[pfcarl] (Mus musculus) PubMed

 20596.

OsSULTR3;3 plays an important role in grain metabolism, pointing to a new route to generate value-added grains in rice and other cereal crops.[OsSULTR3;3] (Mus musculus) PubMed

 20597.

Study describes the identification and characterization of 2 novel regulators named AutA and AutR. Results indicate that AutA could activate the upaB transcription, while AutR inhibited the upaB transcription due to directly suppressing the activating effect of AutA on UpaB expression. [AutA & AutR] (Mus musculus) PubMed

 20598.

ABF1 transcription factor improves drought tolerance by activating the transcription of COR413-TM1 [ABF1] (Mus musculus) PubMed

 20599.

EMP11 serves as a factor for the splicing of mitochondrial nad1 introns and is required for mitochondrial function to ensure proper seed development in maize. [EMP11] (Mus musculus) PubMed

 20600.

This study describes the crystal structure of the O2 -tolerant membrane-bound nickel-iron hydrogenase of Ralstonia eutropha (ReMBH), using krypton-pressurized crystals. [nickel-iron hydrogenase] (Mus musculus) PubMed

 20601.

Methods for Identifying and Examining HTLV-1 HBZ Post-translational Modifications. (Mus musculus) PubMed

 20602.

The aim was to identify the docking effect of certain antifungal compounds upon the transcription factor effectively controlling FLU1.[FLU1] (Mus musculus) PubMed

 20603.

Spo0A directly activates botulinum neurotoxin E synthesis through binding to the putative Spo0A-binding box within the botulinum neurotoxin E promoter. Spo0A is the first known botulinum neurotoxin regulator in C. botulinum type E. [Spo0A] (Mus musculus) PubMed

 20604.

FgSRP1 is important for conidiation, and pathogenesis and alternative splicing is important for its normal functions (FgSRP1; also called FGRRES_09864) (Mus musculus) PubMed

 20605.

Study demonstrates that AMA-1 among Babesis bovis populations from geographically different locations in Thailand were conserved with low levels of genetic diversity in regard to the predicted B-cell epitopes.[AMA-1] (Mus musculus) PubMed

 20606.

Domain reorientation by c-di-GMP complexation with MrkH, which leads to a highly compacted structure, suggests a mechanism by which the protein is activated to bind DNA. [MrkH] (Mus musculus) PubMed

 20607.

the influence of mutations on lactose binding, provide dynamical insights into the interactions of FaeG with lactose, were investigated.[FaeG] (Mus musculus) PubMed

 20608.

Study identified two Morus notabilis Phytochelatin synthase (PCS) genes based on a genome-wide analysis of the Morus genome database. Full-length MnPCS1 and MnPCS2 cDNAs were 1509 and 1491bp long, respectively. The results indicated that PCS1 and PCS2 genes play important roles in heavy stress tolerance and accumulation. [PCS1 & PCS2] (Mus musculus) PubMed

 20609.

PiAgo1 plays an essential role in gene regulation.[PiAgo1] (Mus musculus) PubMed

 20610.

Results suggest that downregulation of long noncoding RNAs (lncRNAs) AK156230 is involved in the induction of cellular senescence through its roles in autophagy and cell cycle progression: [AK156230] (Mus musculus) PubMed

 20611.

Data provide evidence for four alternatively splicing isoforms of BmYki with similar transcriptional expression patterns in Bombyx mori. They are shown to be expressed at comparatively high levels in the silk glands, and may play roles in the regulation of growth-related biological processes with different effects on the expression of Yki targets. [Yki). (Mus musculus) PubMed

 20612.

the catalytic mechanism of DMML, studying five different substrates and two different active site metals configurations using molecular dynamics (MD) and hybrid quantum mechanics/molecular mechanics (QM/MM) calculations, is reported.[DMML] (Mus musculus) PubMed

 20613.

Work identifies a safe harbor locus, rbRosa26, in the rabbit genome. The rbRosa26 encodes two ubiquitously expressed noncoding RNA variants, and is amenable to nuclease mediated knock-in. [Rosa29] (Mus musculus) PubMed

 20614.

a PIMT-mediated, protein repair mechanism is initiated during seed development in rice, with each isoform playing a distinct, yet coordinated, role.[PIMT1, PIMT2] (Mus musculus) PubMed

 20615.

Here, the authors show, using high-resolution live cell imaging, that streptolysin S induces a dramatic osmotic change in red blood cells, leading to cell lysis. This osmotic change was characterized by the rapid influx of Cl(-) ions into the red blood cells through SLS-mediated disruption of the major erythrocyte anion exchange protein, band 3.[streptolysin S] (Mus musculus) PubMed

 20616.

The phytochrome FphA physically interacted with the histidine-containing phosphotransfer protein YpdA and caused light-dependent phosphorylation of the MAP kinase SakA and its shuttling into nuclei.]FphA, SakA, YpdA] (Mus musculus) PubMed

 20617.

the results suggest that Vps17 specifically functions as a retromer component with the cargo-selective complex and also plays a distinct role in the regulation of endosome dynamics during fungal development and plant infection. [Vps17] (Mus musculus) PubMed

 20618.

OsCLT1 plays an important role in glutathione homeostasis, probably by mediating the export of gamma-glutamylcysteine and glutathione from plastids to the cytoplasm, which in turn affects Arsenic and Cadmium detoxification in rice.[OsCLT1] (Mus musculus) PubMed

 20619.

evidence demonstrating that MoGlo3 is required for normal cellular transport and for normal growth, differentiation and pathogenicity (MoGlo3) (Mus musculus) PubMed

 20620.

LRK2 functions as a positive regulator of the drought stress response and tiller development via increased branch development in rice. (Mus musculus) PubMed

 20621.

Quantum mechanical calculations on the doubly reduced FeMo-cofactor with a Fe-bound hydride and S-bound proton (E2(2H) state) favor a direct reaction of CO2 with the hydride ("direct hydride transfer" reaction pathway), with facile hydride transfer to CO2 yielding formate. [FeMo-cofactor] (Mus musculus) PubMed

 20622.

These results support the view that DNA adenine methylation via the dam methylase plays an important role in modulating the pathogenicity of Klebsiella pneumoniae genotype K1.[dam] (Mus musculus) PubMed

 20623.

the gene Lba1680 from L. acidophilus strain 05-172 is induced by lactose, and this lactose induction is not affected by glucose repression. [Lba1680] (Mus musculus) PubMed

 20624.

ChuW is a radical S-adenosylmethionine methyltransferase in Escherichia coli O157:H7 that catalyzes a radical-mediated mechanism facilitating iron liberation and the production of the tetrapyrrole product, anaerobilin. [ChuW] (Mus musculus) PubMed

 20625.

Myotrophin regulates capping protein activity in Dictyostelium discoideum. [Myotrophin] (Mus musculus) PubMed

 20626.

These results suggest that rice stripe virus requires NS3 self-interaction to suppress RNA silencing and to thereby counter host defenses.[NS3] (Mus musculus) PubMed

 20627.

The results suggest that HvCslD2-mediated cell wall changes in the epidermal layer represent an important defence reaction both for nonhost and for quantitative host resistance against nonadapted wheat and host-adapted barley powdery mildew pathogens, respectively.[HvCslD2] (Mus musculus) PubMed

 20628.

In this study, crystal structures of the P450 BM3 M7 heme domain variant with and without cobalt (III) sepulchrate are reported. [P450 BM3] (Mus musculus) PubMed

 20629.

This study found found polymorphisms in the pncA gene for 70% of multidrug-resistant and 96% of extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa and Georgia.[pncA] (Mus musculus) PubMed

 20630.

Optimization of splice site sequences or mutation of nearby cytosines eliminated ICP27-mediated splicing inhibition, and introduction of C-rich sequences to an ICP27-insensitive splicing reporter conferred this phenotype, supporting the inference that specific gene sequences confer susceptibility to ICP27 (Mus musculus) PubMed

 20631.

Dissection of membrane-binding and -remodeling regions in two classes of bacterial phospholipid N-methyltransferases, PmtA, has been described. [PmtA] (Mus musculus) PubMed

 20632.

Trigger factor acts as a mechanical foldase by promoting protein folding under force.[Trigger factor] (Mus musculus) PubMed

 20633.

The thermostable type I L-asparaginase from Thermococcus kodakarensis (TkA) is composed of 328 amino acids and forms homodimers in solution, with the highest catalytic activity being observed at pH 9.5 and 85 degrees C. It has a Km value of 5.5 mM for L-asparagine, with no glutaminase activity being observed. [L-asparaginase] (Mus musculus) PubMed

 20634.

Here, using electron cryotomography, we explore V. cholerae's cytoplasmic chemoreceptor array and establish that it is formed by proteins from cluster I. We further identify a chemoreceptor with an unusual domain architecture, DosM, which is essential for formation of the cytoplasmic arrays. DosM contains two signaling domains and spans the two-layered cytoplasmic arrays. (Mus musculus) PubMed

 20635.

Our finding updated the current knowledge on the regulation of KaiA's function. This work would deepen our understanding of the KaiABC oscillator, and should be conceptually useful in the design of artificial biological oscillators. (Mus musculus) PubMed

 20636.

Lipopolysaccharides promote binding and unfolding of the antibacterial colicin E3 rRNAse domain. [colicin E3] (Mus musculus) PubMed

 20637.

The EndoQ activity was clearly enhanced by addition of PCNA in vitro. The physical interaction between the two proteins through a PIP-motif of EndoQ and the toroidal structure of PCNA are critical for the stimulation of the endonuclease activity.[PCNA, EndoQ] (Mus musculus) PubMed

 20638.

We found that the absence of non-essential translation factors Rrf1 or Mif3, which act at the recycling/initiation steps, also compensates for the respiratory deficiency of yeast bcs1 mutations (Mus musculus) PubMed

 20639.

We demonstrated in high light experiments that CF1Fo ROS targets were involved in the significant inhibition of ATP synthesis rates. Molecular events upon modification of CF1Fo by ROS will be considered. (Mus musculus) PubMed

 20640.

Chromosomal localization of aromatic alcohol dehydrogenase fast-migrating isoenzyme Aadh1F (CAD1-F) gene in Triticum aestivum L. bread wheat (Mus musculus) PubMed

 20641.

encodes a glycosylphosphatidylinositol-anchored lipid transfer protein necessary for pollen exine development [Ms1] (Mus musculus) PubMed

 20642.

VSG role in the immune evasion [VSG] (Mus musculus) PubMed

 20643.

the ability of AOX to maintain critical mitochondrial and chloroplast functions during extreme drought is likely due, at least in part, to its ability to reduce oxidative damage.[AOX] (Mus musculus) PubMed

 20644.

CYP102G4 from Streptomyces cattleya naturally produces indigo. [CYP102G4] (Mus musculus) PubMed

 20645.

Findings provide evidence that the HCV protein NS3 can downregulate PPM1A by promoting its ubiquitination and proteasomal degradation, which might contribute to the migration and invasion of hepatoma cells and may represent a new strategy of HCV in carcinogenesis. [NS3] (Mus musculus) PubMed

 20646.

Mutations or deletions in ramR, leading to the overexpression of RamA predominated in clinical multi-drug-resistant (MDR) E. aerogenes isolates and were associated with a higher-level of expression of efflux pump components. Mutability of RamR may play a key role in predisposing E. aerogenes towards the emergence of a MDR phenotype [ramR]. (Mus musculus) PubMed

 20647.

The present work supports a major role of MdMYB93 in the regulation of suberin deposition in russeted apple skins.[MdMyb93] (Mus musculus) PubMed

 20648.

These findings suggest that E. amylovora recruits multiple stimuli-sensing systems, including HrpX/HrpY, the Rcs phosphorelay system and the Gac-Csr system, to regulate hrpS and T3SS gene expression. (Mus musculus) PubMed

 20649.

This study reports the first crystal structure of cytoplasmic serine hydroxymethyltransferase from Pichia pastoris (pcSHMT) diffracted to 2.5A resolution in space group C2221. [serine hydroxymethyltransferase] (Mus musculus) PubMed

 20650.

The authors identified a novel Lpp-dependent association between functional KpsD and peptidoglycan, highlighting important interplay between cell envelope components required for resistance to complement-mediated lysis in uropathogenic Escherichia coli isolates.[Lpp, KpsD] (Mus musculus) PubMed

 20651.

The mRNA export factor Sus1 plays an important role in oxidative stress tolerance and pathogenesis. [Sus1] (Mus musculus) PubMed

 20652.

CYP76AD1-1 is involved in betalain biosynthesis during the hypocotyl pigmentation process in quinoa. [CYP76AD1-1] (Mus musculus) PubMed

 20653.

AVB is involved in the maintenance of the normal cell division pattern in lateral primordia development and that the AVB gene is required for procambium establishment following auxin signaling.[AVB] (Mus musculus) PubMed

 20654.

Transient expression of Avh238 in Nicotiana benthamiana revealed that nuclear localization is essential for triggering cell death.[Avrh238] (Mus musculus) PubMed

 20655.

These observations link the activity of PntAB in Synechocystis directly to mixotrophic growth.[PntAB] (Mus musculus) PubMed

 20656.

The stress-induced Ca(2+) signaling was dependent on OsPLC1, and the PLC-mediated Ca(2+) signaling was essential for controlling Na(+) accumulation in leaf blades, thus establishing whole plant salt tolerance.[OsPLC1] (Mus musculus) PubMed

 20657.

Surge-Like Luteinising Hormone Secretion Induced by Retrochiasmatic Area NK3R Activation is Mediated Primarily by Arcuate Kisspeptin Neurones in the Ewe [NK3R] (Mus musculus) PubMed

 20658.

a complex between EgMYB1 and EgH1.3 integrates developmental signals to prevent premature or inappropriate lignification of secondary cell walls, providing a mechanism to fine-tune the differentiation of xylem cells in time and space.[egG1.3, EgMYB1] (Mus musculus) PubMed

 20659.

We show by gene disruption that TvPG2 performs a regulatory role on the inducible tvpg1 gene and in triggering the plant immune response. [TvPG2] (Mus musculus) PubMed

 20660.

Highly regulated reactive oxygen species homeostasis is important for Pth11-mediated appressorium formation in M. oryzae.[Pth11] (Mus musculus) PubMed

 20661.

Complex dissemination of the diversified mobilized colistin resistance gene (mcr-1)-bearing plasmids occurs amongst the various E. coli inhabiting the healthy swine populations, in Southern China. (Mus musculus) PubMed

 20662.

CYP76F14 gene co-locates with a quantitative trait locus for (E)-8-carboxylinalool content in grape berries.[CYP76F14] (Mus musculus) PubMed

 20663.

GDP-state specific Rab32-protease [GtgE] (Mus musculus) PubMed

 20664.

The absence of LIMP reduces initial mosquito infection by 50%, impedes salivary gland invasion 10-fold, and causes a complete absence of liver invasion as mutants fail to attach to host cells.[LIMP] (Mus musculus) PubMed

 20665.

PPAR-beta increases PGC-1alpha content via a reduction in protein degradation. [PPAR-beta] (Mus musculus) PubMed

 20666.

CENH3 nucleosomes contain phosphorylated H2AThr133 in centromeric regions.[H2A] (Mus musculus) PubMed

 20667.

FatM and RAM2 role in lipid biosynthesis and development of arbuscular mycorrhiza.[FatM] [RAM2] (Mus musculus) PubMed

 20668.

Subsequently, transcriptional analysis revealed that expression of intercellular adhesin (ica) gene, icaADBC, increased in a mazFsa deletion mutant. mazFsa/icaADBC double gene deletion and genetic complementation approaches provided convincing evidence that increased biofilm formation was caused by an increase in polysaccharide intercellular adhesin synthesized by icaADBC-encoded proteins.[MazF] (Mus musculus) PubMed

 20669.

INO80-C has at least two distinct functions during homologus recombination-DNA end resection and presynaptic filament formation.[INO80] (Mus musculus) PubMed

 20670.

Rv1076 is a novel secretory esterase of M. tuberculosis which could be a potential immunodominant antigen of M. tuberculosis [Rv1076] (Mus musculus) PubMed

 20671.

MaDREB1-MaDREB4 are nucleus-localized, induced by ethylene and encompass transcriptional activation activities.[MaDREB1-MaDREB4] (Mus musculus) PubMed

 20672.

data indicate that WISH likely functions as an upstream sensor for the activation of the G-protein signaling pathway in a cAMP-independent manner (WISH) (Mus musculus) PubMed

 20673.

These results suggest that UB3 regulates vegetative and reproductive branching by modulating cytokinin biosynthesis and signaling in maize and rice.[UB3] (Mus musculus) PubMed

 20674.

The replication protein of pHW126 auto-controls its expression. [rep] (Mus musculus) PubMed

 20675.

MADS87 regulates seed size and thermal sensitivity. (Mus musculus) PubMed

 20676.

These data suggest that both BmGeminin1 and BmGeminin2 are involved in the regulation of DNA replication.[Geminin 2] (Mus musculus) PubMed

 20677.

Verticillium dahliae PevD1 indirectly activates Arabidopsis CRY2 by antagonizing NRP functions. The promotion of CRY2-mediated flowering by a fungal effector outlines a novel pathway by which an external stimulus is recognized and transferred in changing a developmental program. [PevD1] (Mus musculus) PubMed

 20678.

Shoot phosphate content, abundance of root-internal and -external fungal structures, mycorrhizal phosphorus uptake, and accumulation of transcripts encoding plant PHT1 family phosphate transporters varied among lines.[PHT1] (Mus musculus) PubMed

 20679.

Chlamydomonas VTC2 lacks negative feedback regulation by ascorbate in the physiological concentration range.[VTC2] (Mus musculus) PubMed

 20680.

these findings indicate that CDK11A/B interacts with Cyclin L1 to regulate the cell cycle.[CDK11A, CDK11B] (Mus musculus) PubMed

 20681.

Loss of EMP9 function abolishes the C-to-U editing of ccmB-43 and rps4-335 sites in mitochondria.[EMP9] (Mus musculus) PubMed

 20682.

ABF1 functions redundantly with OsbZIP40 to delay floral transition upon water deficit.ABF1 acts as a transcription activator[ABF1] (Mus musculus) PubMed

 20683.

SWEET11 is a nodule specific sucrose transporter.SWEET11 is expressed in Rhizobia-infected root hair cells [SWEET11] (Mus musculus) PubMed

 20684.

results suggest that the MHG1 protein plays an important role in the maintenance of mitochondrial DNA, and mitochondrial abnormality caused by mtDNA aberration is responsible for the short-lifespan of the mhg1(KO) strain (MHG1) (Mus musculus) PubMed

 20685.

AvrStb6 encodes a small, cysteine-rich, secreted protein that produces an avirulence phenotype on wheat cultivars carrying the Stb6 resistance gene.[Stb6] (Mus musculus) PubMed

 20686.

Arabidopsis rbcs mutants expressing a Chlamydomonas SSU differed from wild-type plants with respect to Rubisco catalysis, photosynthesis and growth.[rbcS] (Mus musculus) PubMed

 20687.

Experiments conducted using HPLC/MS in a heterologous system as well as in vitro transport assays with labelled substrate revealed that MtABCG10 is responsible for the membrane translocation of 4-coumarate and liquiritigenin, molecules representing key branching points in the phenylpropanoid pathway. [ABCG10] (Mus musculus) PubMed

 20688.

data suggest that the ArsR-family transcriptional regulator DepR2 negatively regulates production of daptomycin by directly repressing the expression of its gene cluster in S. roseosporus; this is the first report to show the involvement of an ArsR-family regulator in the direct regulation of secondary metabolite biosynthesis in Streptomyces (Mus musculus) PubMed

 20689.

Exchange of activating ATP to inactivating ADP triggers short helical segments in the K(+)-translocating KtrB dimer to organize into two long helices that penetrate deeply into the regulatory RCK domains, thus connecting nucleotide-binding sites and ion gates.[KtrB] (Mus musculus) PubMed

 20690.

Data suggest that glucocorticoids transcriptionally regulate expression of microRNA-19b via glucocorticoid receptor-mediated direct DNA binding mechanism; microRNA-19b is an essential target for glucocorticoid-mediated control of adipose tissue browning. [MIR19, microRNA 19] (Mus musculus) PubMed

 20691.

S-adenosyl-L-methionine-dependent methyltransferase crystal structure consists of a Rossmann-like fold (domain I) and a substrate-binding domain.The cofactor S-adenosyl-L-methionine molecule binds at the interface between adjacent subunits, presumably near to the active site(s) of the enzyme.[SAM-dependent methyltransferase] (Mus musculus) PubMed

 20692.

The expressed prokaryotic PprI protein has distinct effects of the prevention and treatment on acute radiation injury of mammal. [ pprI protein; Deinococcus radiodurans] (Mus musculus) PubMed

 20693.

activates mouse Th1 through TLR2-mediated MyD88-dependent pathway and TLR4-mediated TRIF-dependent pathway in mouse CD4(+)T cells (Mus musculus) PubMed

 20694.

Pi02860 activity is mediated by potato NRL1 protein.[Pi02860] (Mus musculus) PubMed

 20695.

Here, the authors present evidence that in addition to the previously characterized fusobacterial adhesin RadD, the interaction between Fusobacterium nucleatum ATCC 23726 and Streptococcus gordonii V288 involves a second outer membrane protein, which we named coaggregation mediating protein A (CmpA).[CmpA] (Mus musculus) PubMed

 20696.

DEK36 plays role in the mitochondrial transcripts editing and seed development.[DEK36] (Mus musculus) PubMed

 20697.

At the same time, CDPK4 is required for the assembly of the subsequent mitotic spindle and to phosphorylate a microtubule-associated protein important for mitotic spindle formation. (Mus musculus) PubMed

 20698.

TOEFAZ1 is a multimeric scaffold for recruiting proteins that control the timing and location of cleavage furrow ingression. [TOEFAZ1} (Mus musculus) PubMed

 20699.

findings show that the cell wall integrity pathway components MpkA and RlmA as well as the calcium/calcineurin-responsive transcription factor CrzA regulate the expression of cell wall biosynthetic genes during the caspofungin paradoxical effect [CrzA]. (Mus musculus) PubMed

 20700.

investigation to study the Ppd-B1 PI allele with an increased number of copies and characterize the functional specifications of this allele and its interaction with other photoperiod genes (Mus musculus) PubMed

 20701.

presentation of four structural snapshots from the type II-A system of Enterococcus faecalis Cas1 and Cas2 during spacer integration [Cas1 & Cas2] (Mus musculus) PubMed

 20702.

The study showed that BcXYG1 is apoplastic and possibly interacts with the proteins of the plant cell membrane and also that the BcXYG1 cell death-promoting signal is mediated by the leucine-rich repeat receptor-like kinases BAK1 and SOBIR1. (Mus musculus) PubMed

 20703.

Here we show that Rcs-dependent colanic acid production maintains the transmembrane electrical potential and proton motive force in cooperation with the Psp response. In this study, we provide evidence that colanic acid maintains the transmembrane potential and proton motive force during envelope stress. This work provides a new and fundamental insight into bacterial physiology [ Rcs-colanic acid]. (Mus musculus) PubMed

 20704.

These results imply that OsPRI1, which is ubiquitinated by OsHRZ1, mediates rice responses to Fe deficiency by positively regulating OsIRO2 and OsIRO3 expression as part of the OsHRZ1-OsPRI1-OsIRO2/3 signal transduction cascade. [HRZ1;PRI1] (Mus musculus) PubMed

 20705.

Results indicate that gata4 (Po-gata4) is involved in gonadal development by regulating rspo1 (R-spondin1) expression: [GATA4] (Mus musculus) PubMed

 20706.

CagA role in the overcoming podocyte filtration barrier via p38 MAPK signaling pathway [CagA] (Mus musculus) PubMed

 20707.

we established that activin A plays a functional role in hair follicle neogenesis in human DP cells as well as in mouse dermal cells. [Activin A] (Mus musculus) PubMed

 20708.

Structural characterization of purine nucleoside phosphorylase from human pathogen Helicobacter pylori [purine nucleoside phosphorylase] (Mus musculus) PubMed

 20709.

candidates for interacting partners of the tail domain of DcNMCP1 [NMCP1] (Mus musculus) PubMed

 20710.

Serine residues at positions 162 and 166 of the rabies virus phosphoprotein are critical for the induction of oxidative stress in rabies virus infection. [Phosphoprotein P] (Mus musculus) PubMed

 20711.

amyloid properties of the YghJ M60-like domain [YghJ] (Mus musculus) PubMed

 20712.

Findings indicate a pivotal role for ZNF32 function in SOX2 expression and regeneration regulation: [ZNF32] (Mus musculus) PubMed

 20713.

Data show that the self-assembly of Chp F in solution is a rapid, pH-dependent process that occurs independently of disulfide bond formation. Films formed at the air/water interface differed in activity and morphology as a function of pH: at pH 10.0, the film was homogenous, with higher surface activity than at pH 3.0, where long fibrils and aggregates were randomly orientated in a film also containing micropores. [Chp F] (Mus musculus) PubMed

 20714.

recombinant NS1, expressed and purified from eukaryotic cells, induces cytokine production via TLR4 but not TLR2/6.[NS1] (Mus musculus) PubMed

 20715.

GreA impedes DNA break repair; the absence of GreA limits RecBCD-mediated resection (Mus musculus) PubMed

 20716.

established that SpA binds to a substantial proportion of SPA mantle cell lymphom(MCL)-derived immunoglobulins in vitro. Data indicate that many MCL BCRs do not recognize classical high-affinity antigens via conventional CDR-mediated contacts. Instead, a substantial proportion of MCL cases may be driven by BCR signaling through CDR-independent interactions. [SpA] (Mus musculus) PubMed

 20717.

The X-ray structure of the CO dehydrogenase accessory protein CooT was obtained, which revealed that this protein is a homodimer featuring a fold that resembles an Sm-like domain, suggesting a role in RNA metabolism that was however not supported by experimental observations. [CooT] (Mus musculus) PubMed

 20718.

The last four amino acids of the NleF carboxy terminus are essential in inhibiting caspase-4-dependent inflammatory cell death. (Mus musculus) PubMed

 20719.

Both a topoisomerase II paralog with exclusive pronuclear expression and Spo11 are prerequisites for post-meiotic DNA double-strand break induction. Reduced post-meiotic DNA double-strand break induction blocks euchromatin formation, characterized by histone H3K56 acetylation, leading to a failure in gametic nuclei production.[Topoisomerase type II beta, Spo11] (Mus musculus) PubMed

 20720.

Results suggest that the CSP balanced polymorphism does not causally underlie population differentiation. Therefore, when strains carrying different pherotypes encounter one another during cocolonization, genetic exchange can occur without restriction. [CSP] (Mus musculus) PubMed

 20721.

Slr1143 is a new Cph2-interacting regulatory factor which modulates motility under red light. [Slr1143, Cph2] (Mus musculus) PubMed

 20722.

Genetic analysis of sporozoite factors reveals the 6-cysteine domain protein P36 as a major parasite determinant of host cell receptor usage.[P36] (Mus musculus) PubMed

 20723.

RpoN2- and FliA-regulated fliTX is indispensible for flagellar motility and virulence.[RpoN2] (Mus musculus) PubMed

 20724.

Overall, Trypanosoma brucei Erv1 seems to have a role in the mitochondrial translocation and Fe-S cluster assembly in the organelle. (Mus musculus) PubMed

 20725.

HhoA solved the structure of the Synechocystis HhoA protease in complex with a co-purified peptide by X-ray crystallography (Mus musculus) PubMed

 20726.

The fission yeast Lar7 has been identified as a member of the conserved LARP7 family. Lar7 has conserved RNA-recognition motifs, which bind telomerase RNA to protect it from exosomal degradation. [Lar7] (Mus musculus) PubMed

 20727.

Rp1 role in defense resistance.Rp1 forms complex with HCT and CCoAOMT.[Rp1] [HCT] (Mus musculus) PubMed

 20728.

Identification, characterization, immobilization, and mutational analysis of a novel acetylesterase with industrial potential (LaAcE) from Lactobacillus acidophilus. (Mus musculus) PubMed

 20729.

A new IMP allelic variant (IMP-55) metallo-beta-lactamase has been identified in a clinical strain of Acinetobacter baumannii. [IMP-55 beta-lactamase] (Mus musculus) PubMed

 20730.

IolQ encodes a repressor of the iolX transcription. [ iolX ] (Mus musculus) PubMed

 20731.

These results suggest that zOGR1, but not GPR4, is also a metal-sensing G-protein-coupled receptor in addition to a proton-sensing G-protein-coupled receptor, although not all metals that activate hOGR1 activated zOGR1. (Mus musculus) PubMed

 20732.

The PedH (PP_2679) pyrroloquinoline quinone-dependent alcohol dehydrogenase exhibits enzyme activity on a range of substrates similar to that of its Ca(2+)-dependent counterpart PedE (PP_2674), including linear and aromatic primary and secondary alcohols, as well as aldehydes, but only in the presence of lanthanide ions, including La(3+), Ce(3+), Pr(3+), Sm(3+), or Nd(3+).[PedH] (Mus musculus) PubMed

 20733.

Altogether, these results are consistent with the model that the high-affinity site of HypB functions as a nickel site during [NiFe]-hydrogenase enzyme maturation and that the metal selectivity is controlled by activation of metal release by SlyD. [HypB, SlyD, [NiFe]-hydrogenase] (Mus musculus) PubMed

 20734.

Cg0911 encodes an enzyme with histidinol-phosphate phosphatase activity. [cg0911] (Mus musculus) PubMed

 20735.

Recently, a lactate racemase was discovered as a new Ni-dependent enzyme with a unique tethered NAD-like cofactor. This is the first computational study aimed at deciphering the previously unclear role of the Ni-tethered cofactor in reactions of the lactate racemase. The calculations revealed that the cofactor increases the dehydrogenation barriers. [Ni-Dependent Lactate Racemase] (Mus musculus) PubMed

 20736.

Two-hairpin RNA structure acts for transcription termination upstream of nosR and the binding of NasT to H1 facilitates read-through transcription to induce nos expression. [NasT] (Mus musculus) PubMed

 20737.

A. phagocytophilum MSP4 and HSP70 are involved in host-pathogen interactions, with a role for HSP70 during pathogen infection. [MSP4, HSP70] (Mus musculus) PubMed

 20738.

Based upon these data, and what is known regarding the post-translational regulation of IsdG and IsdI, it is proposed that only IsdG is a member of the heme iron acquisition pathway and IsdI regulates heme homeostasis. [IsdG, IsdI] (Mus musculus) PubMed

 20739.

Chaplin E: The pH sensitivity of Chaplin E peptide structure provides a route to control peptide assembly and may be important for the physiological function of this peptide, as a surface active agent in the transition from vegetative to aerial growth. (Mus musculus) PubMed

 20740.

These data indicate that Ralstonia solanacearum GMI1000 suppresses hypersensitive response by inhibiting host catalases through RipAK at early stages of infection.[RipAK] (Mus musculus) PubMed

 20741.

AvrRpt2 virulence factor specifically blocks the flagellin-induced activation of the Arabidopsis MPK11 and MPK4.[AvrRpt2] (Mus musculus) PubMed

 20742.

AAE3 acts as an oxalyl-CoA synthetase and plays role in the resistance to bacterial blight and aluminium toxicity[AAE3] (Mus musculus) PubMed

 20743.

All1123 protein is not involved in photoprotection or heterocyst formation. [All1123] (Mus musculus) PubMed

 20744.

Based on structural analyses and genetic and biochemical experiments, the authors identify an alpha-helical switch that shifts a carbonyl oxygen into the active site to coordinate a metal cofactor.[SpoIIE] (Mus musculus) PubMed

 20745.

By RT-PCR, it was found that the overexpression of gt1 could increase the glycerol content in cells and repress the expression of mxr1 and aox1, and the deletion of gt1 reduced the glycerol content in cells and promoted the expression of aox1.[mxr1, aox1, gt1] (Mus musculus) PubMed

 20746.

It was found that the hexameric form of glutamate decarboxylase was most stable at pH 6 and in presence of NaCl or KCl. [glutamate decarboxylase ] (Mus musculus) PubMed

 20747.

While most trafficking functions were intact in Fab1 deficient cells, including both endocytic and biosynthetic trafficking to the lysosome, lysosomal turnover of an endogenous ubiquitinylated membrane protein, ISG65, was completely blocked suggesting that TbFab1 plays a role in the endosomal sorting complexes required for transport-mediated late endosomal/multivesicular body degradative pathways.[Fab1] (Mus musculus) PubMed

 20748.

RAD52 and HDF1 contribute to maintain the metabolic state, in a different way, during chronological aging in S. cerevisiae.[RAD52; HDF1] (Mus musculus) PubMed

 20749.

Recombinant PE_PGRS18 heterologously expressed in M. smegmatis is cell-wall-associated. The M. smegmatis bacteria carrying this recombinant showed differential response to stresses and altered the production of host cytokines IL-6, IL-1beta, IL-12p40 and IL-10, as well as enhanced survival within macrophages largely via attenuating the apoptosis of macrophages. (Mus musculus) PubMed

 20750.

DksA is epistatic to HapR and RpoS and comprises a complex regulatory circuit in regulating the expression of HAP. [DksA , HapR, Hap] (Mus musculus) PubMed

 20751.

The genes putA (bab2_0518) and putR (bab2_0517) are critical for the chronic infection of mice by B. abortus, but putA and putR are not required for the survival and replication of the bacteria in naive macrophages. [putA, putR] (Mus musculus) PubMed

 20752.

FnrS downregulates isc gene cluster expression on the protein level. [FnrS] (Mus musculus) PubMed

 20753.

The mixed-linkage (1-->3),(1-->4)-d-glucan (MLG) specific glycosyl hydrolase lichenase is an important biochemical tool for the structural characterization of MLGs. This study reports the automated synthesis of seven MLG oligosaccharides and their application in the characterization of the active site of lichenase. [lichenase] (Mus musculus) PubMed

 20754.

finding show PtAUREO1a and 1b are not functionally redundant in photoacclimation to blue light - [PtAUREO1a and 1b] (Mus musculus) PubMed

 20755.

The inulosucrase hugO open reading frame is 1335 bp long and encodes a predicted protein of 444 amino acids. [ hugO ] (Mus musculus) PubMed

 20756.

Two pivotal roles for MEICA1 in meiosis: preventing aberrant meiotic recombination and regulating crossover formation [ MEICA1] (Mus musculus) PubMed

 20757.

Drl1 controls the development of key agronomic traits in maize.[Drl1] Drl2 controls the development of key agronomic traits in maize.[Drl2] (Mus musculus) PubMed

 20758.

RipAW and RipAR localized to the cytoplasm of plant cells and significantly suppressed pattern-triggered immunity responses.[RipAW and RipAR] (Mus musculus) PubMed

 20759.

Hippo role in the differentiating stem cells.[Hippo] (Mus musculus) PubMed

 20760.

WRKY6 is associated with gibberellin-suppressed leaf senescence of Chinese Flowering Cabbage.[WRKY6] (Mus musculus) PubMed

 20761.

These results demonstrated that LdtR controls the expression of nearly 180 genes in Liberibacter asiaticus, distributed in processes such as cell motility, cell wall biogenesis, energy production, and transcription.[LtdR] (Mus musculus) PubMed

 20762.

CbrA/CbrB two-component system negatively affects alginate synthesis.[CbrA,CbrB ] (Mus musculus) PubMed

 20763.

These results indicate that Fur positively modulates Helicobacter pylori J99 motility through interfering with bacterial flagellar switching.[Fur] (Mus musculus) PubMed

 20764.

Results show that YidC possesses an aqueous membrane cavity localized to the membrane inner leaflet. Both the scanning data and the MD simulations show that the lipid-exposed transmembrane helices 3, 4, and 5 are short, leading to membrane thinning around YidC. Close examination of the MD data reveals previously unrecognized structural features that are likely important for protein stability and function. [YidC] (Mus musculus) PubMed

 20765.

Purification of PlcA from the supernatant of Lb. plantarum NI326 resulted in an active peptide with a molecular mass of 5,570 Da, corresponding to that predicted from the (processed) PlcA amino acid sequence.[PlcA] (Mus musculus) PubMed

 20766.

The lplA2 gene can be activated as an alternative pathway to compensate for the loss of LplA1 activity and to maintain lipoic acid metabolism. [LplA1 ; LplA2] (Mus musculus) PubMed

 20767.

In this study, the authors identified a Candida albicans inositol polyphosphate multikinase, Ipk2. Down-regulation of IPK2 enhanced the ability of hyphal development, increased expression of hypha-specific genes and promoted transport of hypha-specific factors.[Ipk2] (Mus musculus) PubMed

 20768.

The mechanisms of fluoroquinolone resistance in A. veronii isolates may be related to mutations in gyrA codon 83 and parC codon 87 and the presence of the qnrS2 gene. [parC], [gnrS2] (Mus musculus) PubMed

 20769.

PLA2G12A protein, mouse. Our data establish Pla2g12a as an atheroprotective candidate gene in mice, where high expression levels in ECs and macrophages may limit the recruitment and accumulation of these cells in nascent atherosclerotic lesions (Mus musculus) PubMed

 20770.

Globotriaosylceramide (Gb3), the receptor of Fhb, was involved in this process and affected S. suis infection-induced activation of myosin light chain 2 through Rho/ROCK signaling in hCMEC/D3 cells. [Fhb] (Mus musculus) PubMed

 20771.

Momyo2 plays pleiotropic roles in fungal development, and is required for the full pathogenicity of M. oryzae.[myo2] (Mus musculus) PubMed

 20772.

Jamm1 protein helix structure is conserved and crucial for binding ubiquitin-like protein domains. [JAMM1] (Mus musculus) PubMed

 20773.

Strawberry fruit contain the allergenic Fra a proteins, members of the pathogenesis-related 10 protein family that causes oral allergic syndrome symptoms. Fra a expression was not directly regulated by auxin, but might be associated with the ripening process and/or external factors in a paralog-specific manner. [Fra a] (Mus musculus) PubMed

 20774.

Loss-of-function mutations in ARE1 cause delayed senescence and result in 10-20% grain yield increases.[ARE1] (Mus musculus) PubMed

 20775.

AdeN confers elevated virulence in Acinetobacter baumannii.[AdeN] (Mus musculus) PubMed

 20776.

EsrB strongly induces type III and type VI secretion systems expression and that it modulates the expression of both physiology- and virulence-associated genes. [EsrB] (Mus musculus) PubMed

 20777.

[ORF6 protein} ORF6 protein may be involved in caspases regulation and the expression of multiple cytokines in PCV2-infected cells (Mus musculus) PubMed

 20778.

MRP D1 domain is involved in SS2 strain virulence and eloquently demonstrate the function of MRP in pathogenesis of infection.[MRP] (Mus musculus) PubMed

 20779.

These data demonstrate that paracoccin acts as a Paracoccidioides brasiliensis contributory virulence factor directly affecting fungal pathogenesis. (Mus musculus) PubMed

 20780.

Prevalence of gyrA mutations in nalidixic acid-resistant strains of Salmonella enteritidis isolated from humans, food, chickens, and the farm environment in Brazil has been reported. [gyrA] (Mus musculus) PubMed

 20781.

the Lotus japonicus NITRATE UNRESPONSIVE SYMBIOSIS 1 (NRSYM1) gene encoding a NIN-LIKE PROTEIN transcription factor acts as a key regulator in the nitrate-induced pleiotropic control of root nodule symbiosis [NRSYM1] (Mus musculus) PubMed

 20782.

YtvA light-oxygen-voltage domain goes through global structural change during photoactivation and signaling.[YtvA] (Mus musculus) PubMed

 20783.

thioredoxin 1 may play an important role in controlling the redox status in P. lutzii which may contribute to this organism's virulence [TRX1] (Mus musculus) PubMed

 20784.

These findings are the first to confirm that the porcine ILF2 interacts with the nsp9 and nsp2 of porcine reproductive and respiratory syndrome virus in vitro, and exerts negative regulatory effect on the replication of the virus.[nsp9] (Mus musculus) PubMed

 20785.

Our study was the first to use CRISPR/Cas9 genome editing for the functional study of an important, conserved genetic element of var genes-the intron-in an endogenous, episome-free manner. Our findings shed light on the role of the var gene intron in transcriptional regulation of monoallelic expression[var2csa]. (Mus musculus) PubMed

 20786.

Taken collectively the results suggest that positioning of pneumolysin into the cell wall compartment in active form, together with glycosyl hydrolases and adhesins, requires a functional accessory SecA2Y2 system.[SecA2Y2] (Mus musculus) PubMed

 20787.

Gn glycoprotein crystal structure reveals a novel fold.Gn glycoprotein forms a complex with Gc glycoprotein on the surface of the virion.[Gn glycoprotein] (Mus musculus) PubMed

 20788.

Cotton Ascorbate Oxidase plays an important role in fiber cell elongation and may promote cell growth by generating the oxidation of apoplasts, via the auxin-mediated signaling pathway. [ascorbate oxidase] (Mus musculus) PubMed

 20789.

This study demonstrated that the increased expression of efflux pump genes such as mdfA and acrA can lead to levofloxacin resistance in E. coli.[mdfA; acrA] (Mus musculus) PubMed

 20790.

Analysis of junction sequences confirmed the occurrence of a simple tandem duplication of defensin7 with sequence identity at the junction, suggesting nonallelic homologous recombination between defensin7 and defensin6 The duplication event generated two chimeric promoters that are best explained by gene conversion followed by homologous recombination. (Mus musculus) PubMed

 20791.

our OxsA structures show an active site that switches from a dinuclear to a mononuclear metal center as phosphates are eliminated from substrate. (Mus musculus) PubMed

 20792.

OsMYB45 plays an important role in tolerance to Cadmium (Cd) stress in rice. [OsMYB45] (Mus musculus) PubMed

 20793.

VapC toxin inhibition as a method for prevention of the formation of resting forms of mycobacteria (Mus musculus) PubMed

 20794.

a banana NAC protein, MusaSNAC1 which induced stomatal closure by elevating hydrogen peroxide content in guard cells during drought stress, is reported.[SNAC1] (Mus musculus) PubMed

 20795.

cdh6b Cadherin-6B plays a key role in the specification and delamination of the neural crest population in the early chick embryo. (Mus musculus) PubMed

 20796.

Results showed that dgcA negatively affected virulence, EPS production, bacterial autoaggregation and motility, but positively triggered biofilm formation via modulating the intracellular c-di-GMP levels. [dgcA] (Mus musculus) PubMed

 20797.

The plasmid-borne mphA confers high-level azithromycin resistance in Shigella isolates. [mphA] (Mus musculus) PubMed

 20798.

The plasmid-borne mphA confers high-level azithromycin resistance in Shigella isolates. [mphA] (Mus musculus) PubMed

 20799.

MdPIN1b was expressed preferentially in BC and M9, and the expression of MdPIN1b was significantly lower in the phloem of M9 interstem than that in the scion and rootstock.[MdPIN1b] (Mus musculus) PubMed

 20800.

Study identified PsbO protein to be lysine-acetylated. Functional studies performed by site-directed mutagenesis show that Mutation of the K190 acetylation site resulted in a distinguishable phenotype. Compared with the K190R mutant, the K190Q mutant exhibited a decreased oxygen evolution rate and an enhanced cyclic electron transport rate in vivo. [PsbO] (Mus musculus) PubMed

 20801.

In order to better understand the roles that melanocortin receptors (cMCRs) and melanocortin-2 receptor accessory proteins (cMRAP1 and cMRAP2) play in the HPA axis and hypothalamus, adrenal gland and hypothalamus mRNA from 1day-old white leghorn chicks (Gallus gallus), were analyzed by real-time PCR.[MRAP1, MRAp2] (Mus musculus) PubMed

 20802.

TPP1F was identified as binding partner of Dictyostelium GPHR.[GPHR] (Mus musculus) PubMed

 20803.

The study identified 2 hha paralogues EC042_4516 and EC042_4796 (termed hha2 and hha3 respectively) in the annotated genome of strain 042 by performing a Blast searching and provide evidence for a strong correlation between the presence of these paralogues and the virulence phenotype of several E. coli strains.[hha2 & hha3]. (Mus musculus) PubMed

 20804.

Ca2+-binding protein CAS has Ca(2+)-binding activity, and the perturbation of intracellular Ca(2+) homeostasis: [CAS] (Mus musculus) PubMed

 20805.

RNA-induced ring closure templates a sequential ATP-hydrolysis mechanism, provide a molecular rationale for how the Rho ATPase domains distinguishes between distinct RNA sequences. (Mus musculus) PubMed

 20806.

Kruppel homolog 1 maintains the immature stage by suppressing E93 (early ecdysone response gene) in the penultimate nymphal stage (N4).[Kruppel homolog 1, E93] (Mus musculus) PubMed

 20807.

Murine cytomegalovirus IE3-dependent transcription from the viral genome plays a crucial role in activating DAI/ZBP1-dependent necroptosis. This implicates RNA transcripts generated by a large double-stranded DNA virus as a biologically relevant ligand for DAI/ZBP1 during natural viral infection [IE3]. (Mus musculus) PubMed

 20808.

vaspin could inhibit the osteogenic differentiation in vitro, and the PI3K-Akt/miR-34c loop might be the underlying mechanism.[Vaspin] (Mus musculus) PubMed

 20809.

Hir3 was present in repressing conditions for CreA and in both growth conditions for CreB, suggesting that Hir3, or proteins interacting with Hir3, could be a possible target of CreB (Mus musculus) PubMed

 20810.

Our hypothetical model presents the RuBisCO pathway of hybrid necrosis in wheat and explains how Ne1 and Ne2 interact at molecular level. (Mus musculus) PubMed

 20811.

Cusativin is a cytidine-specific ribonuclease. [cusativin] (Mus musculus) PubMed

 20812.

The presence of PTOX led to a highly oxidized state of the NAD(P)H/NAD(P)(+) pool, as detected by NAD(P)H fluorescence. Moreover, in the PTOX overexpressor the electron transport capacity of PSI relative to PSII was higher, indicating an alteration of the photosystem I (PSI) to photosystem II (PSII) stoichiometry.[PTOX] (Mus musculus) PubMed

 20813.

Transgenic wheat lines with increased SBPase protein levels and activity from a Brachypodium distachyon gene contstruct were grown under greenhouse conditions and showed enhanced leaf photosynthesis and increased total biomass and dry seed yield. [SBPase] (Mus musculus) PubMed

 20814.

GhoT forms an alpha helical structure in lipid bilayers that agrees with the structure predicted by the I-TASSER protein structure prediction program. The structure generated using I-TASSER was used to conduct coarse-grained molecular dynamics simulations, which indicate that GhoT damages the cell membrane, as a multimer, by forming transient transmembrane pores. [GhoT] (Mus musculus) PubMed

 20815.

The enrichment of CRZR and AKHR in the primary and secondary sex organs, respectively, of adult mosquitoes, these neuropeptides may play a role in regulating mosquito reproductive biology. [CRZR] (Mus musculus) PubMed

 20816.

To gain insights into copper homeostasis, we investigated the roles of a copper transcription factor Afmac1 in the life-threatening fungus Aspergillus fumigatus, a homolog of the yeast MAC1. We observed that the Afmac1 deletion mutant exhibited not only significantly slower growth, but also incomplete conidiation including a short chain of conidia and defective melanin (Mus musculus) PubMed

 20817.

Structural analysis of a sugar N-formyltransferase that specifically functions on dTDP-3-amino-3,6-dideoxy-d-galactose.[N-formyltransferase] (Mus musculus) PubMed

 20818.

study identifies Fatty acid (FAs) as physiological effectors for the SaeRS system and reveals a connection between cellular lipid homeostasis and the regulation of virulence factor transcription. FA kinase is widely distributed in Gram-positive bacteria, suggesting similar roles for FA kinase in these organisms [SaeR, SaeS] (Mus musculus) PubMed

 20819.

study identifies a 12-nucleotide Pho7 DNA binding motif [5'-TCG(G/C)(A/T)xxTTxAA] in the promoters of phosphate-regulated genes, pinpoints DNA and protein features important for Pho7 binding to DNA, and correlates them with Pho7-dependent gene expression in vivo st [Pho7]. (Mus musculus) PubMed

 20820.

These studies have led to the proposal that the feoABC locus has two promoters: an upstream P1 promoter whose expression is relatively iron-independent but repressed under microaerobic conditions and the known downstream Fur-regulated P2 promoter.[feoABC] (Mus musculus) PubMed

 20821.

FLExDUX4 line of mice is quite versatile and will allow new investigations into mechanisms of DUX4-mediated pathophysiology as well as much-needed pre-clinical testing of DUX4-targeted FSHD interventions in vivo [Dux4] (Mus musculus) PubMed

 20822.

Steady-state tryptophan fluorescence studies with tryptophan extended peptides, WMreB1-9 and its N-terminal acetylated analog, Ac-WMreB1-9 show preferential binding to negatively-charged liposomes.[MreB] (Mus musculus) PubMed

 20823.

Suggest role for Epstein Barr virus EBER1 in the induction of increased TRAF6 expression in the peripheral B cells of Sjogren's patients. (Mus musculus) PubMed

 20824.

The transcription factor GT2L1D negatively regulates drought tolerance and plant development. [GT2L1D] (Mus musculus) PubMed

 20825.

Structure of a lipid A phosphoethanolamine transferase has been solved. [Lipid A phosphoethanolamine transferase] (Mus musculus) PubMed

 20826.

Psb28 protein binds to cytochrome b559 in Photosystem II. [Psb28] (Mus musculus) PubMed

 20827.

Sulfide-responsive transcriptional repressor SqrR functions as a master regulator of sulfide-dependent photosynthesis. [SqrR] (Mus musculus) PubMed

 20828.

These findings suggest that BerB binds c-di-GMP, and activates RpoN-dependent transcription of the berA gene coding for a c-di-GMP-responsive transcriptional regulator.[BerB, RpoN] (Mus musculus) PubMed

 20829.

These findings indicate that S100A4 gene silencing can inhibit alkali burn-induced corneal neovascularization in rabbits.[S100A4] (Mus musculus) PubMed

 20830.

WOX4a genes control cell division activity in the vascular cambium, and hence growth in stem girth.[WOX4a][WOX4b] (Mus musculus) PubMed

 20831.

Enterohemorrhagic Escherichia coli 869 EF-Ts promotes the formation of GTP.EF-Tu.tRNA ternary complexes, thereby accelerating substrate turnover for rapid depletion of target-cell tRNA. [EF-Ts], [EF-Tu] (Mus musculus) PubMed

 20832.

this study determined the structure of the N-terminal domain of PvRBP2b involved in red blood cell binding, elucidating the molecular basis for TfR1 recognition. [ PvRBP2b ] (Mus musculus) PubMed

 20833.

The isolation and characterization of E. coli strains carrying the blaNDM-5 gene from dairy cattle is reported.[NDM-5 protein, E. coli] (Mus musculus) PubMed

 20834.

single-molecule fluorescence resonance energy transfer to direct observation of conformational changes associated with the functional transitions in the Listeria monocytogenes Ca(2+)-ATPase (LMCA1), an orthologue of eukaryotic Ca(2+)-ATPases; identification of key intermediates with no known crystal structures and show that Ca(2+) efflux by LMCA1 is rate-limited by phosphoenzyme formation (Mus musculus) PubMed

 20835.

Heat shock protein crystal structure of VcHsp15 at 2.33 Angstroms. Exhibits a trimeric form and shares a strikingly similar fold with several rna binding proteins[HSP15] (Mus musculus) PubMed

 20836.

Characterization and Mutational Analysis of Two UDP-Galactose 4-Epimerases, GalESp1 and GalESp2, in Streptococcus pneumoniae TIGR4 (Mus musculus) PubMed

 20837.

PMS1T is a producing phased small-interfering RNA that regulates photoperiod-sensitive male sterility in rice [PMS1T] (Mus musculus) PubMed

 20838.

The findings of this study indicated that RbsR plays roles in the bacterial adhesion and intracellular survival of Aeromonas hydrophila.[RbsR] (Mus musculus) PubMed

 20839.

structural model suggests that the diverse FIV and HIV-1 Vifs use conserved residues for Cullin 5 binding, FIV Vif binds Cullin 5 independently of zinc, in contrast to HIV-1 Vif. (Mus musculus) PubMed

 20840.

OsHAC4 is an Arsenic (As)(V) reductase that is critical for As(V) detoxification and for the control of As accumulation in rice.[OsHAC4] (Mus musculus) PubMed

 20841.

in diabetic hearts, I/R-induced cardiac NS expression is obviously impaired, resulting in a subsequent ribosomal biogenesis dysfunction. (Mus musculus) PubMed

 20842.

The results indicated that AcuC was an important regulatory protein contributing to the pathogenicity of Aeromonas hydrophila.[AcuC] (Mus musculus) PubMed

 20843.

Study report the expression, purification, crystallization and 2.10 A X-ray structure of 3CL(pro) from PEDV. Analysis of the PEDV 3CL(pro) structure and comparison to other coronaviral 3CL(pro)'s from the same alpha-coronavirus phylogeny shows that the overall structures and active site architectures across 3CL(pro)'s are conserved, with the exception of a loop that comprises the protease S2 pocket. [3CLpro] (Mus musculus) PubMed

 20844.

the expression levels of GLAST and GS and of glial fibrillary acidic protein (GFAP, a marker of neuronal stress) in chick retina exposed to 2000 lux under 12-h light:12-h dark (12L:12D; normal photoperiod), 18L:6D (prolonged photoperiod), and 24L:0D (constant light), are reported.[GS, GLASt] (Mus musculus) PubMed

 20845.

SDG701 is a major rice H3K4-specific methyltransferase.SDG701 is involved in induction of expression of some rice flowering regulatory genes.[SDG701] (Mus musculus) PubMed

 20846.

Data suggest that p7 is a critical immune evasion protein that suppresses the antiviral interferon function by counteracting the function of IFI6-16. (Mus musculus) PubMed

 20847.

TOB1, TOB2 AND TOB3 regulate the maintenance and fate of all reproductive meristems and are required to maintain proper function of the spikelet and branch meristems in rice.[TOB1][TOB2][TOB3] (Mus musculus) PubMed

 20848.

RaxX is similar in sequence to plant peptide containing sulfated tyrosine.RaxX promotes root growth similar to plant PSY peptides. (Mus musculus) PubMed

 20849.

Therefore, the authors suggest that G4 enhances virus production through abrogation of viral RNA accumulation.[G4] (Mus musculus) PubMed

 20850.

Finally, Fur derepression and RecA activation in enterohemorrhagic Escherichia coli O157 were shown to participate in the nitric oxide-enhanced Stx1 and Stx2 production, respectively.[stx1, stx2] (Mus musculus) PubMed

 20851.

Collectively, the results presented here confirmed a new physiological role for CalR that acts as an activator for cpsQ-mfpABC and mfpABC transcription.[CalR] (Mus musculus) PubMed

 20852.

OsGCD1 is essential for rice fertility and is required for dorsal-ventral pattern formation and endosperm free nucleus positioning.[OsGCD1] (Mus musculus) PubMed

 20853.

These results provide a mechanistic explanation as to why rpaA-null mutants die in the dark, further connect the clock to metabolism under diurnal growth, and indicate that RpaA likely has important unidentified functions during the day. [regulator of phycobilisome association A - RpaA] (Mus musculus) PubMed

 20854.

In this study, we describe the dual role of the transcription factor Xylanase promoter binding protein 1 (Xpp1) in the regulation of both primary and secondary metabolism of Trichoderma reesei. [Xpp1] (Mus musculus) PubMed

 20855.

data show that single amino acid substitutions in the 2A peptide can have a major influence on viral protein synthesis, virus viability, and polyprotein processing. They also indicate that efficient "cleavage" at the 2A/2B junction is required for optimal virus replication. However, maximal StopGo activity is not essential for the viability of FMDV. (Mus musculus) PubMed

 20856.

The tangled1 mutant was fully rescued by introduction of cortical division site localized TANGLED1-YFP. A CYCLIN1B destruction box was fused to TANGLED1-YFP to generate a line that mostly rescued the division plane defect but still showed cell-cycle delays when expressed in the tangled1 mutant (Mus musculus) PubMed

 20857.

Csa3M006660 is the most likely candidate gene for Ms-3, the cucumber male sterility gene [Csa3M006660, or Ms-3] (Mus musculus) PubMed

 20858.

CIDEB interacts with the HCV NS5A protein, and the N terminus of CIDEB and the domain I of NS5A are involved in this interaction.[NS5A] (Mus musculus) PubMed

 20859.

ZmEREB156 could bind to the ZmSSIIIa promoter but not the Zmsh2 promoter in a yeast one-hybrid system. Thus, ZmEREB156 positively modulates starch biosynthetic gene ZmSSIIIa via the synergistic effect of sucrose and ABA. (Mus musculus) PubMed

 20860.

this is the first demonstration that activity of the RPC5 subunit is critical for proper functionality of RNA Polymerase III and normal plant development.[RPC5] (Mus musculus) PubMed

 20861.

phenotype of the determinate growth trait is controlled by one recessive gene, Bnsdt1 [Bnsdt1] (Mus musculus) PubMed

 20862.

During hepatic replication, the C-terminal region of EXP-1 binds to host ApoH. This molecular interaction plays a pivotal role for successful Plasmodium liver-stage development. Truncated EXP-1 protein, missing the specific ApoH interaction site, or down-regulation of ApoH expression impaired intrahepatic development, delayed blood-stage patency, and affected disease outcome. [EXP-1] (Mus musculus) PubMed

 20863.

findings have important implications for understanding the molecular mechanisms of PRRSV replication and pathogenicity (Mus musculus) PubMed

 20864.

the putative chondroitin binding protein M083 plays a critical role during the pathogenesis of myxoma virus in susceptible Oryctolagus rabbits by impacting viral dissemination through changes in the transfer of virions onto primary splenocytes. (Mus musculus) PubMed

 20865.

OsCPK17 activity depends on its structural rearrangement induced by calcium binding, and that the protein can be autophosphorylated. The identified phosphorylation sites mostly populate the OsCPK17 N-terminal domain. (Mus musculus) PubMed

 20866.

CcTFL1 is a candidate gene for growth habit in pigeonpea [TFL1] (Mus musculus) PubMed

 20867.

A tetR21 mutant, QT21, exhibited a 4-fold increase in the transcription level of lmrS Staphylococcus aureus. lmrS overexpressor showed increases of 4-fold and 2-fold, respectively, in the Minimum Inhibitory Concentrations of chloramphenicol and erythromycin, while the Minimum Inhibitory Concentrations of lmrS mutant QT18 and lmrS-tetR21 mutant QT1821 remained similar to those of parental strain RN6390. [TetR21] (Mus musculus) PubMed

 20868.

Epstein-Barr Virus protein EB2 first is recruited to the mRNA cap structure in the nucleus and then interacts with the proteins eIF4G and PABP to enhance the initiation step of translation. [EB2] (Mus musculus) PubMed

 20869.

Results found that BbATG1 and BbATG8 are required for autophagy, growth under starvation, spore differentiation (including conidia and blastospores) and virulence in B. bassiana. Also, BbATG8, but not BbATG1, is crucial for fungal resistance to oxidative stress. [ATG8] (Mus musculus) PubMed

 20870.

Theses results establish SidJ as a ubiquitin-deconjugating enzyme that functions to impose temporal regulation on the activity of SidE effectors. SidJ may be important in future studies of signaling cascades mediated by this unique ubiquitination, one that also potentially regulates cellular processes in eukaryotic cells. [sidJ] (Mus musculus) PubMed

 20871.

KASP markers for the greenbug resistance gene Gb7 and the Hessian fly resistance gene H32 were mapped in wheat [Gb7; H32] (Mus musculus) PubMed

 20872.

Study used microsecond molecular dynamics simulations to explore the effect of stalk deletion on enzymatic activity, contrasting NA proteins from the A/swine/Shandong/N1/2009 strain both with and without a stalk deletion; showed that the geometry and dynamics of the neuraminidase enzymatic pocket may differ depending on stalk length. [NA, H1N1 pandemic reference strain A/California/04/2009, GenBank: FJ966084.1] (Mus musculus) PubMed

 20873.

QYr.nwafu-6BL is a stripe rust resistance gene in hexaploid wheat [QYr.nwafu-6BL] (Mus musculus) PubMed

 20874.

ts, or Csa1G056960, plays an important role in the formation of multicellular tender spines in cucumber fruit [Csa1G056960; ts] (Mus musculus) PubMed

 20875.

The "lid" in the Streptococcus pneumoniae SrtC1 sortase adopts a rigid structure that regulates substrate access to the active site. [SrtC1] (Mus musculus) PubMed

 20876.

M2 ubiquitination plays an important role in infectious virus production by coordinating the efficient packaging of the viral genome into virus particles and the timing of virus-induced cell death. [M2] (Mus musculus) PubMed

 20877.

SUMO conjugation motifs mutations within the protein V coding sequence are beneficial for adenoviral replication. Blocking protein V SUMOylation at specific sites shifts the onset of viral DNA replication to earlier time points during infection and promotes viral gene expression. (Mus musculus) PubMed

 20878.

Results show that the membrane domain of the ComD protein forms six transmembrane segments with three extracellular loops, loopA, loopB and loopC. Both loopC and loopB are required for Quorum sensing activation by signal pheromone (CSP) recognition, while loopA plays little role. A deletion or substitution mutation of four residues NVIP in loopC abolishes CSP recognition for quorum sensing activities. [ComD] (Mus musculus) PubMed

 20879.

PEDV nsp1 blocked the nuclear translocation of IRF1 and reduced the number of peroxisomes to suppress IRF1-mediated type III IFNs. Mutational studies showed that the conserved residues of nsp1 were crucial for IRF1-mediated IFN-lambda suppression. [nsp1] (Mus musculus) PubMed

 20880.

The 25 kDa subunit of the Clevage Factor Im (CFIm25) is an essential factor for messenger RNA polyadenylation in human cells. [CFIm25] (Mus musculus) PubMed

 20881.

Depletion of Apoc1 protein results in a neural border formation defect and loss of border fates, including neural crest cells[apoc1] (Mus musculus) PubMed

 20882.

These results collectively suggest that ChiIV3 acts as a likely antifungal protein and as a receptor for unidentified chitin in planta to trigger cell death and defense signaling against Phytophthora capsici inoculation.[ChilV3] (Mus musculus) PubMed

 20883.

Data reported the cloning and characterization of GhABF2, encoding for typical cotton bZIP TF. Overexpression of GhABF2 significantly improved drought and salt stress tolerance. Its expression was induced by drought and ABA treatments but repressed by high salinity. Transcriptome analysis indicated that GhABF2 increases drought and salt tolerance by regulating genes related to ABA, drought and salt response. [ABF2] (Mus musculus) PubMed

 20884.

our data indicate that oxalate turned on EMT of renal tubular cells that could be prevented by EGCG via Nrf2 pathway. These findings also shed light onto development of novel therapeutics or preventive strategies of renal fibrosis in the future. (Mus musculus) PubMed

 20885.

study investigated the structural dynamics of CooA upon CO dissociation; results indicate the formation/dissociation of the Fe-Pro2 bond induces a conformational change in CooA, strongly suggesting that the CO-dependent activation of CooA is induced by the dissociation of Pro2 from the heme iron [CooA] (Mus musculus) PubMed

 20886.

The recombinant UDP-galactose: cyanidin galactosyltransferase 1 (UCGalT1) galactosylated cyanidin to produce cyanidin-3-O-galactoside and showed optimal activity for cyanidin at 30 degrees C and pH 8.6.[UCGalT1] (Mus musculus) PubMed

 20887.

The GN4-1 gene promoted accumulation of cytokinins in the inflorescence and increased grain number per panicle [GN4-1] (Mus musculus) PubMed

 20888.

A strategy for acquiring structural information from sparsely isotopically labeled large proteins is illustrated with an application to the E. coli heat-shock protein, HtpG (high temperature protein G), a 145 kDa dimer.[HtpG] (Mus musculus) PubMed

 20889.

Bph34 is the major locus contributing to Brown planthopper resistance [Bph34] (Mus musculus) PubMed

 20890.

Pm59 is a novel powdery mildew resistance gene, and confers resistance to Blumeria graminis [Pm59] (Mus musculus) PubMed

 20891.

zinc-mediated regulation of the SREBP-SCD axis in lipid metabolism, distinct from the negative regulation of SREBP-1 or SREBP-2 by phosphatidylcholine or cholesterol [SCD] (Mus musculus) PubMed

 20892.

FlabarinL is dispensable for developmental differentiation.FlabarinL is associated with the paraflagellar rod and the flagellar membrane.FlabarinL is a result of a gene duplication of Flabarin.[FlabarinL] (Mus musculus) PubMed

 20893.

CHRF lncRNA negatively regulates miR-489 in pulmonary fibrosis. (Mus musculus) PubMed

 20894.

Results demonstrated that RelA is a bifunctional enzyme, which could synthesize and hydrolyze (p)ppGpp, whereas RelQ is a monofunctional (p)ppGpp synthetase in Streptococcus suis. [RelA, ReQ] (Mus musculus) PubMed

 20895.

Results provide compelling evidence that P protein stability is regulated by the cellular cdc37 which aids the P protein to load onto the Hsp90 machinery after rabies virus infection. [P protein] (Mus musculus) PubMed

 20896.

Study determined the crystal structure of LbTDC in complex with pyridoxal 5-phosphate (PLP). Semi-saturation mutagenesis on the conformationally flexible H241 residue shows that only H241N and H241Q retained low activity, indicating that H241 is vital for the conformation required to bind PLP and tyrosine. Alanine scanning mutagenesis revealed several residues that influence activity and specificity. (Mus musculus) PubMed

 20897.

our findings enrich the ovine miRNA database, and outline the miRNA transcriptome of sheep during skeletal muscle development. Moreover, we show that miR-192 affects SCs proliferation and myogenic differentiation via down-regulation of RB1. (Mus musculus) PubMed

 20898.

The QSAR and MDS results obtained from this work should be useful in determining structural requirements for inhibitor development as well as in designing more potential inhibitors for NS2B-NS3 protease (Mus musculus) PubMed

 20899.

A short linear motif in the unstructured N-terminal region of Chaetomium thermophilum Nup145C, a subunit of the Y-complex, that is sufficient to recruit the Nup82 complex. [Nup145C, Nup82] (Mus musculus) PubMed

 20900.

A novel allele of TaGW2-A1 increases grain weight but decreases grain number [TaGW2-A1] (Mus musculus) PubMed

 20901.

the class IV homeodomain-associated leucine zipper transcription factor GLABROUS (CmGL) plays a role in multicellular trichome initiation [GLABROUS (CmGL)] (Mus musculus) PubMed

 20902.

study describes an additional role for Streptococcus mutans SpaP as adhesin in interspecies adherence with RadD-SpaP as the interacting adhesin pair for binding between S. mutans and F. nucleatum ssp. polymorphum (Mus musculus) PubMed

 20903.

study describes an additional role for Streptococcus mutans SpaP as adhesin in interspecies adherence with RadD-SpaP as the interacting adhesin pair for binding between S. mutans and F. nucleatum ssp. polymorphum [RadD] (Mus musculus) PubMed

 20904.

this paper shows that the increased resistance to oxidative stress in isp-1 worms does not account for their longevity, and that resistance to oxidative stress can be experimentally dissociated from lifespan NCBI Gene Expression Omnibus (GEO): GSE95240 (Mus musculus) PubMed

 20905.

Here we describe that a partial deletion of the speB 5' UTR caused a general accumulation of mRNA in the stationary phase, and that the mRNA accumulation was due to retarded mRNA degradation [speB]. (Mus musculus) PubMed

 20906.

BIV Rev interacts with nucleolar phosphoprotein B23 in cells.[rev] (Mus musculus) PubMed

 20907.

E protein is critical for efficient and optimal virus replication and propagation, and thereby for neurovirulence. [E protein] (Mus musculus) PubMed

 20908.

A putative SR1P binding pocket that is formed by the C-terminal GapA helix 14 and flanked by the N-terminal helix 1 as well as two random coiled regions. [SR1P] (Mus musculus) PubMed

 20909.

Rda1 and Rda2 are two loci associated with resistance to Phomopsis cane spot [Rda1; Rda2] (Mus musculus) PubMed

 20910.

Study presents the first crystal structure of soluble periplasmic globular domain of PbgA from E. coli, which revealed that the globular domains of PbgA resemble the structures of the arylsulfatase protein family and contains a novel core hydrophobic pocket that may be responsible for binding and transporting cardiolipins. [PbgA] (Mus musculus) PubMed

 20911.

HmsC might play a major role in sensing the environmental changes. [HmsC] (Mus musculus) PubMed

 20912.

study reports that HesF's secretion signal peptide is located in its C-terminus, and show that a heterologous reporter protein fused with HesF's secretion signal could be successfully secreted (Mus musculus) PubMed

 20913.

Study shows 3 putative cavities on the FMDV-SAT1 (FMDV Southern African Territories1) capsid as possible binding sites for the receptor-mediated viral entry into the host cell and, demonstrates the significance of VP1, in the formation of FMDV-SAT1 surface cavities, which is the main component in all the identified cavities. (Mus musculus) PubMed

 20914.

Functional studies revealed that OsAHL1 regulates root development under drought condition to enhance drought avoidance, participates in oxidative stress response and also regulates the content of chlorophyll in rice leaves (Mus musculus) PubMed

 20915.

In this study we have established that S2 from EIAV is an infectivity factor functionally related to Nef of primate lentiviruses and to glycosylated Gag of gammaretroviruses. S2 therefore is a third example of a retroviral factor capable of promoting retrovirus infectivity by counteracting the SERINC family of proteins. [S2] (Mus musculus) PubMed

 20916.

interaction between TaPBF and the Glu-1 promoter hypomethylation is involved in modulating the expression of the Glu-1 genes, which increases glutenin accumulation [TaPBF-D; Glu-1] (Mus musculus) PubMed

 20917.

Study used the Glu-B3 deletion mutant CB037C to investigate the molecular characteristics and functional properties of the Glu-B3h gene. The results provide new insights into the allelic variation mechanism and molecular basis of gluten quality formation. The Glu-B3h gene, with specific structural features, showed potential value for wheat gluten quality improvement through use of SNP-based molecular markers. (Mus musculus) PubMed

 20918.

BnIND double mutants display higher silique shatter resistance [INDEHISCENT of BnIND] (Mus musculus) PubMed

 20919.

inactivation of CovS not only derepresses CovR-controlled genes but also abrogates the acidic-stress-dependent repression of the genes; these phenomena may significantly increase bacterial virulence during infection. [CovS] (Mus musculus) PubMed

 20920.

differential expression analysis was performed to compare the wild type strain to a mutant lacking the response regulator CtrA, an important regulator of gene expression in R. capsulatus.[CtrA] (Mus musculus) PubMed

 20921.

Lr79 is a leaf rust resistant gene mapped to chromosome 3BL [Lr79] (Mus musculus) PubMed

 20922.

first crystal structures of hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (Mus musculus) PubMed

 20923.

Isolates confirmed as E. coli by phenotypic method were further tested for the presence of attaching and effacing (eae) and bundle-forming pilus (bfpA) genes by real-time SYBR Green-based polymerase chain reaction. (Mus musculus) PubMed

 20924.

Overexpression of Adenylyl Cyclase Encoded by the Mycobacterium tuberculosis Rv2212 Gene Confers Improved Fitness, Accelerated Recovery from Dormancy and Enhanced Virulence in Mice.[ Rv2212 ] (Mus musculus) PubMed

 20925.

The purpose of this study is to investigate interactions involving an occasionally trapped oxygen molecule (O2) at the so-called Qo site of the cytochrome bc1 complex, which is one of the central active sites of the protein complex, where redox reactions are expected to occur. The study revealed charge transfer modes from amino acid residues and cofactors at the Qo-site to the trapped O2 molecule. [cytochrome bc1] (Mus musculus) PubMed

 20926.

Numerous time-resolved studies of the Pr to Pfr photoisomerization in phytochrome Cph1 have revealed multiphasic excited-state decay kinetics. Here this study probes spectral signatures of ground-state heterogeneity of Pr Isomer of Phytochrome Cph1. [Cph1] (Mus musculus) PubMed

 20927.

These data show how Sar1 drives the polymerization of COPII coat and how Sec16 is spatially distributed during COPII coat polymerization.[Sec16] (Mus musculus) PubMed

 20928.

Study demonstrated that ARFRP1 interacted with NS5A through domain I of NS5A. Indeed, lipid droplet (LD) were accumulated in replicon cells and HCV-infected cells as well. Moreover, NS5A was partially colocalized with LDs. [NS5A] (Mus musculus) PubMed

 20929.

The crystal structure of the UreD-UreF-UreG complex from the human pathogen Helicobacter pylori (HpUreDFG) revealed the presence of tunnels that cross the entire length of both UreF and UreD, potentially able to deliver Ni(II) ions from UreG to apo-urease. [UreD] (Mus musculus) PubMed

 20930.

NtNramp5 is a transporter for Manganese and Cadmium.[NtNramp5] (Mus musculus) PubMed

 20931.

In this study, traditional and high-throughput sequencing was used to characterise three patterns of IS629 inactivation of verotoxin 2 genes in EHEC O157:H7, caused by insertion or insertion followed by partial deletion. At least one of the patterns of inactivation appears to have persisted several years among cattle O157:H7, indicating it has no major effect on fitness in the animal reservoir[verotoxin 2]. (Mus musculus) PubMed

 20932.

The magnetic properties of the Rieske protein purified from Chlorobaculum tepidum were investigated using electron paramagnetic resonance and hyperfine sublevel correlation spectroscopy (HYSCORE). The g-values of the Fe2S2 center were gx = 1.81, gy = 1.90, and gz = 2.03. [Rieske] (Mus musculus) PubMed

 20933.

Pmk1 regulates expression of secreted fungal effector proteins implicated in suppression of host immune defenses, preventing reactive oxygen species generation and excessive callose deposition at plasmodesmata. [Pmk1] (Mus musculus) PubMed

 20934.

The crystal structure of PatA shows glycolipid acceptor binding site and explains the molecular mechanism of substrate recognition and catalysis.[PatA] (Mus musculus) PubMed

 20935.

Data demonstrated that CsPAO4 accounts for production of H2O2 causing oxidative damages under salt stress and that down-regulation of a PAO gene involved in polyamine terminal catabolism may be an alternative approach for improving salt stress tolerance. [PAO4] (Mus musculus) PubMed

 20936.

MTP8.2 mediates Manganese (Mn) tolerance along with MTP8.1 through the sequestration of Mn into the shoot and root vacuoles.[MTP8.2] (Mus musculus) PubMed

 20937.

YdcR temporally regulates the virulence factor SrfN during infection.[YdcR, SrfN] (Mus musculus) PubMed

 20938.

a species-restricted parasite-encoded Hsp70, termed PfHsp70x, which is exported into the host erythrocyte cytosol. PfHsp70x lacks a classical PEXEL/HT motif, and its transport appears to be mediated by a 7 amino acid motif directly following the hydrophobic N-terminal secretory signal. (Mus musculus) PubMed

 20939.

The authors propose that Magnaporthe oryzae employs ARRDC1 to regulate specific receptors in response to conidiation-related signals for conidiogenous cell differentiation and utilize autophagosomes for desensitization of conidiogenous receptor, which transmits extracellular signal to the downstream elements of transcription factors.[ARRDC1] (Mus musculus) PubMed

 20940.

this study reports converging evidence supporting loss of PRDX5 in aves.[PRDX5] (Mus musculus) PubMed

 20941.

LNC00173 noncoding RNA regulates growth of the intestinal mucosa and stimulates intestinal epithelial renewal by reducing levels of miRNA195. (Mus musculus) PubMed

 20942.

In both Fe protein/ATP and electrocatalytic reactions, the FeFe-protein shows a significantly higher distribution of electrons to CO2 reduction compared to the MoFe protein. [MoFe protein, FeFe-protein] (Mus musculus) PubMed

 20943.

Microvirin (MVN) is a carbohydrate-binding protein and shows high specificity for high-mannose type N-glycan structures. Recombinantly expressed MVN oligomers in di-, tri- and tetrameric form were evaluated for their viral inhibition. MVN oligomers bound more efficiently to hepatitis C virus (HCV) virions, and displayed in comparison with the MVN monomer a higher neutralization potency against HCV infection. [microvirin] (Mus musculus) PubMed

 20944.

The expression of the Cucumber Mosaic Virus movement protein (MP) in A. thaliana and N. benthamiana can suppress reactive oxygen species (ROS) production triggered by multiple pathogen-associated molecular patterns (PAMPs), such as bacteria-derived peptide flg22, elf18, and fungal-derived chitin. [movement protein] (Mus musculus) PubMed

 20945.

Iron(II)/alpha-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes [TET1] (Mus musculus) PubMed

 20946.

Of particular interest, is the hypervirulent response in grapevines observed when Xylella fastidiosa is disrupted for production of PrtA, and that Pierce's disease-model tobacco plants transformed to express PrtA exhibited decreased symptoms after infection by Xylella fastidiosa fastidiosa.[PrtA] (Mus musculus) PubMed

 20947.

abnormal PKC-epsilon/PKC-delta ratio promotes the activation of Drp1 signalling, caspase cascades and GSK-3beta-dependent mPTP opening.[mPTP] (Mus musculus) PubMed

 20948.

results confirmed that LbpA is an indigoidine biosynthetic enzyme in the IM-2 signaling cascade [LBpA] (Mus musculus) PubMed

 20949.

Characterization of the cellulosomal scaffolding protein CbpC from Clostridium cellulovorans 743B [CbpC] (Mus musculus) PubMed

 20950.

Substitutions in PBP3 are sufficient to confer resistance to both ampicillin and third-generation cephalosporins in H. parainfluenzae. A combination of substitutions at positions Val-511 and Asn-526 confers resistance to ampicillin. Resistance to third-generation cephalosporins probably requires more than four substitutions in PBP3 [PBP3]. (Mus musculus) PubMed

 20951.

mechanism of the reaction catalyzed by NadA [NadA] (Mus musculus) PubMed

 20952.

these results suggest that OsAIR2 may be associated with the plant response to Arsenic stress and acts as a positive regulator of As stress tolerance.[OsAIR2] (Mus musculus) PubMed

 20953.

Data suggest that nkcc1, ccc2, and ccc3 are differentially expressed in tissues of larvae and adults of this species; nkcc1 and ccc2 are equally expressed in larvae and adults, whereas ccc3 is 100-fold more abundant in larvae than in adults. [nkcc1, Na-K-Cl cotransporter-1; ccc2, cation-chloride cotransporter-2; ccc3, cation-chloride cotransporter-3] (Mus musculus) PubMed

 20954.

EMB2738 and NtEMB2738 are involved in the expression of plastid genes in higher plants.[NtEMB2738] (Mus musculus) PubMed

 20955.

We further discovered that SL1 trans-splicing likely enhances translational efficiency by shortening the native 5' UTRs, hence reducing the presence of upstream start codons (uAUG) and weakening mRNA secondary structures. (Mus musculus) PubMed

 20956.

Potentiometric titration o fhexameric tyrosine-coordinated heme protein HTHP in solution revealed a single redox transition at -0.54 V (vs Ag/AgCl), indicating six structurally identical tyrosine coordinates hemes. [HTHP] (Mus musculus) PubMed

 20957.

In this study the authors identify an E2 enzyme, Triticum aestivum Ubiquitin conjugating enzyme 4 (TaU4) that functions in wheat defence against Septoria. They demonstrate TaU4 to be a bona fide E2 enzyme through an E2 charging assay.[TaU4] (Mus musculus) PubMed

 20958.

Data indicate that miR-UL148D inhibits ACVR1B expression in latently infected cells to limit proinflammatory cytokine secretion, perhaps as an immune evasion strategy or to postpone cytokine-induced reactivation until conditions are more favorable. [miR-UL148D] (Mus musculus) PubMed

 20959.

Here, a theoretical study concerning the diffusion route of ciprofloxacin across the outer membrane porin OmpC from E. coli is presented. [OmpC] (Mus musculus) PubMed

 20960.

Determined is the solution structure of the Cpf1 protein from Francisella novicida (Cpf1) with and without CRISPR RNA (crRNA) using small-angle X-ray scattering, providing the insights into the apo-structure of Cpf1. [Cpf1] (Mus musculus) PubMed

 20961.

Bacteriocin LB44 was purified from soil isolate Pediococcus pentosaceus LB44 using activity-guided chromatography. Bacteriocin LB44 showed broad host range against Gram-positive, Gram-negative and haloarchaea strains tested. [bacteriocin] (Mus musculus) PubMed

 20962.

This work compares the structure and function of wild-type (WT) coproheme decarboxylase from Listeria monocytogenes and its M149A, Q187A, and M149A/Q187A mutants. (Mus musculus) PubMed

 20963.

Determined the crystal structure of HycI at 1.59A resolution to clarify how HycI recognizes its own substrate MbhL. Although the overall structure of HycI is similar to that of its homologous protease HybD, HycI adopts a larger loop than HybD, thereby creating a broad and deep cleft. [HycI, MbhL] (Mus musculus) PubMed

 20964.

Data suggests that expression of CYP4F2 is down-regulated in liver of mice with non-alcoholic fatty liver disease after feeding with high-fat/Western diet and in human hepatocyte cell line exposed to excess palmitic acid, oleic acid, or fructose. [CYP4F2, cytochrome P450 family 4 subfamily F member 2] (Mus musculus) PubMed

 20965.

Tir is translocated to the host plasma membrane in a Golgidependent manner.[Tir] (Mus musculus) PubMed

 20966.

P50 of apple chlorotic leaf spot virus interacts with PR-10 of Malus sylvestris cv. R12740-7A. [RP10] (Mus musculus) PubMed

 20967.

The wcfB gene coding for alpha-1,2-fucosyltransferase from Bacteroides fragilis was screened from eleven candidates of putative alpha-1,2-fucosyltransferase.[Bacteroides fragilis] (Mus musculus) PubMed

 20968.

hopQ genotypes were determined among H. pylori isolates obtained from patients with gastroduodenal disorders and their association with the clinical outcome was assessed. hopQI was present in 35%, while hopQII was positive in 55% . For gastritis subjects, the rate of hopQII compared to hopQI was higher, and a statistically significant difference was found between hopQII genotype and the clinical outcome. hopQ. (Mus musculus) PubMed

 20969.

flavin destructase reaction of BluB from Sinorhizobium meliloti is initiated with canonical flavin-O2 chemistry. A C4a-peroxyflavin intermediate is rapidly formed in BluB upon reaction with O2, and has properties similar to those of flavin-dependent hydroxylases. (Mus musculus) PubMed

 20970.

A conformational change in Vc H-NOX introduced by NO generates a new kinase-binding interface, thus locking the kinase in an inhibitory conformation. (Mus musculus) PubMed

 20971.

The spike protein is composed of an N-terminal receptor-binding domain (S1) and a C-terminal trans-membrane fusion domain (S2). S2 contains a highly conserved heptad repeat 1 and 2 (HR1 and HR2). A recombinant fusion core protein was crystallized and its structure was solved at a resolution of 2.45A. Characterized was the binding of HR1s https:and HR2s via both sequence alignment and structural analysis. [spike protein] (Mus musculus) PubMed

 20972.

In this article an exhaustive theoretical study of the phosphoryl transfer reaction from adenosine triphosphate (ATP) to dihydroxyacetone (Dha) catalyzed by DhaK is reported. The results suggest that the substrate-assisted phosphoryl and proton-transfer mechanism is kinetically more favorable than the mechanism where an aspartate would be activating the Dha. [DhaK] (Mus musculus) PubMed

 20973.

Data show that d-glycero-alpha-d-manno-heptose-1-phosphate guanylyltransferase (HddC) uses GTP for catalysis and suggest that EXXPLGTGGA and L(S/A/G)X(S/G) motifs are probably essential to bind with GTP and a FSFE motif with substrat: [HddC] (Mus musculus) PubMed

 20974.

DNA-Mediated Oxidation of Dps [Dps] (Mus musculus) PubMed

 20975.

A small open reading frame of Escherichia coli O157:H7 strain Sakai (EHEC), designated laoB (L-arginine responsive overlapping gene), is embedded in reading frame -2 in the antisense strand of ECs5115, encoding a CadC-like transcriptional regulator.[CadC, LaoB] (Mus musculus) PubMed

 20976.

This study provides a first, experimentally supported, atomistic view of the interactions between an LPMO and crystalline chitin. (Mus musculus) PubMed

 20977.

Staphylococcal superantigen like 5 (SSL5) inhibits the MMP9 activity through binding to the catalytic domain, and the beta1-3 region is responsible for the inhibition of proteolytic activity of MMP-9. [SSL5] (Mus musculus) PubMed

 20978.

p53 in cytoplasm improves the accuracy of DNA synthesis of HIV-1 reverse transcriptase by removal of the non-canonical dU from the nascent DNA. [HIV-1 reverse transcriptase] (Mus musculus) PubMed

 20979.

Multicompartment global analysis of these data demonstrates that the excited-state photochemistry of PYP depends subtly, but convincingly, on excitation wavelength with similar kinetics with distinctly different spectral features, including a shifted ground-state beach and altered stimulated emission oscillator strengths and peak positions. (Mus musculus) PubMed

 20980.

study confirmed the involvement of the actin cytoskeleton as well as the conserved actin-associated protein Crn1p in trap formation;. it further suggested the manners in which Crn1p influences the development of three-dimensional networks in A. oligospora [Crn1p]. (Mus musculus) PubMed

 20981.

RNase E scarcity reduces stx2 phage production but not toxin in enterohaemorrhagic Escherichia coli TEA028. Normal concentrations of RNase E are likely required for correct phage morphogenesis.[RNase E] (Mus musculus) PubMed

 20982.

The patterns of synonymous codon and amino acid usages for E2 gene might be caused by the equilibrium of evolutionary forces from virus and host. Our work gave new investigations into the role of host origin in the formations of synonymous codon/amino acid usages and the evolutionary trend of BVDV E2 gene. (Mus musculus) PubMed

 20983.

In summary, E3L is an essential gene for Ectromelia virus. (Mus musculus) PubMed

 20984.

Data indicate that knock-down the transcriptional levels of the TaEDS1 genes in a powdery mildew-resistant variety of common wheat compromised resistance: [EDS1] (Mus musculus) PubMed

 20985.

that Cj1415 catalyzes the ATP-dependent phosphorylation of CDP-NH2 to form 3'-phospho-cytidine-5'-diphosphoramidate. Cj1415 will also catalyze the phosphorylation of adenosine diphosphoramidate (ADP-NH2) and uridine diphosphoramidate (UDP-NH2) but at significantly reduced rates. It is proposed that Cj1415 be named cytidine diphosphoramidate kinase. (Mus musculus) PubMed

 20986.

The phage shock protein system (Psp) system has evolved with the ability to detect and detoxify dangerous secretin multimers while ignoring the presence of innocuous monomers [PsP]. (Mus musculus) PubMed

 20987.

identified the apo-petrobactin exporter (ApeX) as a member of the resistance-nodulation-cell division (RND) family of transporter; in the absence of ApeX, petrobactin accumulates inside the cell while continuing to export petrobactin components that are capable of transporting iron; the loss of ApeX does not affect the ability of B. anthracis to cause disease [ApeX] (Mus musculus) PubMed

 20988.

LepA functions in ribosome biogenesis. In cells lacking LepA, immature 30S particles accumulate. 4 proteins are specifically underrepresented in these particles-S3, S10, S14, and S21-all of which bind late in the assembly process and contribute to the folding of the 3' domain of 16S rRNA. Processing of 16S rRNA is also delayed in the mutant strain. (Mus musculus) PubMed

 20989.

A one-step design strategy using phylogenetic analysis and Rosetta atomistic calculations was used to design PfRH5 variants with improved packing and surface polarity. 3 PfRH5 designs all showed improved stability relative to wild type. The best, with 18 mutations relative to PfRH5, expressed in a folded form in bacteria had 10-15 degrees C higher thermal tolerance. than wild type. RH5. (Mus musculus) PubMed

 20990.

Set3 contributes to heterochromatin integrity by promoting transcription of subunits of Clr4-Rik1-Cul4 histone methyltransferase complex in fission yeast. (Mus musculus) PubMed

 20991.

Results presented in the study clearly show that Pol e can robustly support the gap-filling reactions required for both the 5' and 3' nick-directed MMR reactions that have been reconstituted in vitro. [POLQ] (Mus musculus) PubMed

 20992.

HepP Changes within the blood of severely burned patients significantly induced expression of hepP in PA14 (Mus musculus) PubMed

 20993.

Data show that the tetrameric RelQ is a sequence-specific RNA-binding protein. RelQ's enzymatic and RNA binding activities are subject to intricate allosteric regulation. (p)ppGpp synthesis is potently inhibited by the binding of single-stranded RNA. Conversely, RelQ's enzymatic activity destabilizes the RelQ:RNA complex. pppGpp, an allosteric activator of the enzyme, counteracts the effect of RNA. [RelQ] (Mus musculus) PubMed

 20994.

Data show that TraA requires TraB to form an active adhesin for self-recognition. In the absence of TraB, TraA localizes to the cell surface but does not function in cell- binding. TraA contains a predicted sorting motif, MYXO-CTERM, contributing to its cell surface display. TraB, with a beta-barrel and cell wall binding domain, may help anchor TraA to the cell envelop during adhesion and outer membrane exchange. [TraA... (Mus musculus) PubMed

 20995.

To investigate the function of Cg2612, crystal structure was determined. Cg2612 functions as a dimer and shows an overall structure similar to other known LOGs with a similar "PGGXGTXXE" motif that contributes to the formation of an active site . biochemical studies on Cg2612 revealed that the protein has phosphoribohydrolase activity but not LDC activity. [Cg2612] (Mus musculus) PubMed

 20996.

an M. oryzae ortholog of GCN5 (MGG_03677), encoding a histone acetyltransferase (HAT) that negatively regulates light- and nitrogen-starvation-induced autophagy, by acetylating the autophagy protein Atg7, was identified.[Gcn5, Atg7] (Mus musculus) PubMed

 20997.

our findings reveal that secondary transporters and stress-responsive genes may play crucial roles in salt tolerance to bypass the requirement for the CchA-calcineurin pathway, contributing to a deeper understanding of the mechanisms that influence fungal salt stress adaption in Aspergillus (Mus musculus) PubMed

 20998.

ERN1: ERN1 was activated in response to rhizobial infection and depended on CYCLOPS and NSP2. Phylogenetic analysis showed that the lineages of ERN1 and ERN2 genes originated from a gene duplication event in the common ancestor of legume plants. However, genomic analysis suggested the lack of ERN2 gene in the L. japonicus genome. (Mus musculus) PubMed

 20999.

Identify hepatitis C virus genetic variants associated with resistance to antiviral NS5A inhibitors. (Mus musculus) PubMed

 21000.

compared to yeast homologs, Cu family proteins in A. fumigatus may have their own working styles; the Afmac1 deletion strain shows a significantly attenuated pathogenicity in the neutropenic immunocompromised mice model, demonstrating that Afmac1 is required for pathogenesis in vivo [mac1] (Mus musculus) PubMed

 21001.

investigated the role of Chk1 in the low-virulence species Candida guilliermondii, in order to gain insight into putative conservation of the role of group X HHK in opportunistic yeasts; results demonstrate that group X HHK function is not conserved in Candida species [Chk1] (Mus musculus) PubMed

 21002.

Data show that individual protomers within the trimeric glutamate transporter GltPh function fully independently [GltPh] (Mus musculus) PubMed

 21003.

The cystathionine-beta-synthase domain of magnesium and cobalt efflux protein, CorC-cystathionine-beta-synthase domain can simultaneously bind AMP molecules in C3'- and C2'-endo conformations. [CorC] (Mus musculus) PubMed

 21004.

The authors demonstrate that RbmA binds Vibrio exopolysaccharides (VPS) directly and uses a binary structural switch within its first fibronectin type III (FnIII-1) domain to control RbmA structural dynamics and the formation of VPS-dependent higher-order structures.[RbmA] (Mus musculus) PubMed

 21005.

a role for Set2-dependent H3K36 methylation in facilitating DNA replication and the transcriptional responses to both replication stress and DNA damage through promoting MluI cell-cycle box (MCB) binding factor (MBF)-complex-dependent transcription in fission yeast, is reported.[Set2, MBF] (Mus musculus) PubMed

 21006.

Electrostatic interactions are required to bind WaaG to membranes. Hydrophobic interactions are not sufficient. WaaG senses the membrane's surface charge density but there is no preferential binding to specific anionic lipids. The binding is similar to peripheral GTs. Therefore, WaaG may be a peripheral GT and this could be of functional relevance in vivo. No C-terminal domain movement was seen. (Mus musculus) PubMed

 21007.

Transcriptional regulator PrqR plays a negative role in glucose metabolism and oxidative stress acclimation in Synechocystis sp. PCC 6803.[PrqR] (Mus musculus) PubMed

 21008.

Crystal structures of DHDPS and DHDPR from A. variabilis were determined at 1.92 A and 2.83 A, respectively, and show that both enzymes adopt the canonical bacterial tetrameric architecture. These studies indicate that the quaternary structure of bacterial and plant DHDPS and DHDPR diverged after cyanobacteria evolved. (Mus musculus) PubMed

 21009.

Results identified the possible biotin machinery in the Streptococcus suis comprising a single BioY (SSU05_0509) transporter regulated by the BirA bifunctional protein (05SSU_1625) and the biotin-requiring substrate protein AccB (SSU05_1801). [BirA, BioY, AccB] (Mus musculus) PubMed

 21010.

Terpene synthase 16 (CitTPS16) was shown to catalyze synthesis of E-geraniol in vitro, and transient overexpression of CitTPS16 in fruits and leaves of Newhall sweet orange resulted in E-geraniol accumulation in vivo. Among cloned members of the AP2/ERF transcription factor gene family, CitERF71 showed a similar expression pattern to CitTPS16.[ERF71,TPS16] (Mus musculus) PubMed

 21011.

sir1037 the potential crosstalk between CoaR and Slr1307 (i.e., the coregulated genes mediated by CoaR and Slr1037) was identified and validated through quantitative proteomics and quantitative real-time PCR (qRT-PCR), respectively (Mus musculus) PubMed

 21012.

These findings demonstrated that CsrA plays a critical role in E. amylovora virulence and suggested that negative regulation of virulence by GacS/GacA acts through csrB sRNA, which binds to CsrA and neutralizes its positive effect on T3SS gene expression, flagellar formation and amylovoran production. (Mus musculus) PubMed

 21013.

Hemagglutinin-esterase plays a role in a unique binding strategy for virus attachment. [hemagglutinin-esterase] (Mus musculus) PubMed

 21014.

ScmR is a pleiotropic regulator of secondary metabolism, virulence, biofilm formation, and other stationary phase processes.[ScmR] (Mus musculus) PubMed

 21015.

Inhibition of Cdk7 in the parasite led to strong reduction in Serine 5 phosphorylation of TgRPB1-CTD at the promoters of constitutively expressed actin1 and sag1 genes with concomitant reduction of both nascent RNA synthesis and 5'-capped transcripts. Therefore, we provide compelling evidence for crucial role of TgCdk7 kinase activity in mRNA synthesis (Mus musculus) PubMed

 21016.

gRNA-DNA mismatches atprotospacer adjacent motif-distal bases modulate different biophysical parameters that determine association and dissociation rates [Cas9] (Mus musculus) PubMed

 21017.

MeWRKY79 and heat-shock transcription factor 20 (MeHsf20) targeted the W-box and the heat-stress elements in the promoter of N-acetylserotonin O-methyltransferase 2 (MeASMT2), respectively. Taken together, the results indicate that MeASMT2 is a target of MeWRKY79 and MeHsf20 in plant disease resistance.[WRKY79,Hsf20] (Mus musculus) PubMed

 21018.

LytS contains a four-helix bundle, and XylFII contains two Rossmann fold-like globular domains with a xylose-binding cleft between them.In the absence of d-xylose, LytS and XylFII formed a heterodimer.Specific binding of d-xylose to the cleft of XylFII induced a large conformational change that closed the cleft and brought the globular domains closer together.[LytS] [XylFII ] (Mus musculus) PubMed

 21019.

Genes located in the locus of enterocyte effacement (LEE) pathogenicity island were significantly upregulated, whereas expression of flagella-related genes was significantly reduced in the csrA::kan mutant. [CsrA] (Mus musculus) PubMed

 21020.

regulates fatty acid biosynthetic genes (Mus musculus) PubMed

 21021.

GhSCP2D is required for GhPdBG3-2A/D expression to degrade callose at the plasmodesmata, thereby contributing to the establishment of the symplasmic pathway.[GhSCP2D] (Mus musculus) PubMed

 21022.

Sequence diversity identified in the OmpPst1 porins was mainly located in two cell-surface-exposed loops (L5 and L7): these loops were found to be responsible for 80% of the main movements of the protein. [Omp1] (Mus musculus) PubMed

 21023.

Linear alcohols and benzyl alcohol suppress Des synthesis after a temperature downshift. The membrane fluidization induced by alcohols was reflected in an increased hydration at the lipid-water interface. This is associated with a decrease in DesK activity. 2 hydrophilic motifs at opposite ends of theDesK transmembrane region sense temperature-dependent variations in membrane properties. DesK. (Mus musculus) PubMed

 21024.

N-induced OsmiR393 accumulation reduces the expression of OsTIR1 and OsAFB2, which alleviates sensitivity to auxin in the axillary buds and stabilizes OsIAA6, thereby promoting rice tillering. (Mus musculus) PubMed

 21025.

findings show that CtpE belonging to a family of previously uncharacterized bacterial P-type ATPases is involved in specific uptake of Ca(2+) into Mycobacterium smegmatis; intracellular Ca(2+) obtained through CtpE is essential for growth and maintenance of cell surface properties under Ca(2+)-deficient conditions [CtpE] (Mus musculus) PubMed

 21026.

Conversion between two conformational states of KaiC is induced by ATP hydrolysis as a trigger for cyanobacterial circadian oscillation in Synechococcus elongatus PCC 7942. [KaiC] (Mus musculus) PubMed

 21027.

Apicoplast FtsH1 disruption inhibits apicomplexan parasites growth. [FtsH1] (Mus musculus) PubMed

 21028.

It identify a GATA transcription factor elt-2 as a positive regulator of Pprmt-1:: gfp expression and show that elt-2 RNAi decreases endogenous PRMT-1 expression at mRNA and protein levels. (ELT-2 protein) (Mus musculus) PubMed

 21029.

Biochemical and genetic analyses revealed a drought stress-activated mitogen-activated protein (MAP) kinase cascade consisting of GhMAP3K15-Mitogen-activated Protein Kinase Kinase 4 (GhMKK4)-Mitogen-activated Protein Kinase 6 (GhMPK6) that directly phosphorylates GhWRKY59 at residue serine 221.[GhWRKY59] (Mus musculus) PubMed

 21030.

essential for embryonic development [Hox3] (Mus musculus) PubMed

 21031.

Metacaspase 1 (MCA1) is a regulator of cell death and it is important for the interaction between wheat and Puccinia striiformis. [MCA1] (Mus musculus) PubMed

 21032.

OsOFP6 was shown to interfere with auxin in regulating lateral root growth and initiation, as RNAi plants had increased density of lateral roots under IAA (indole-3-acetic acid) treatment. OsOFP6 also affects polar auxin transport.[OFP6] (Mus musculus) PubMed

 21033.

This chromatin-based regulatory mechanism enables ZmCCT to be more precise and timely in defense against F. graminearum infection.[ZmCCT] (Mus musculus) PubMed

 21034.

ZmMs33 encodes a sn-2 glycerol-3-phosphate acyltransferase and is essential for male fertility [ZmMs33] (Mus musculus) PubMed

 21035.

the Ser/Thr protein kinase CsPID is responsible for round leaf shape [CsPID] (Mus musculus) PubMed

 21036.

The protein encoded by Cia8 belongs to the sodium bile acid symporter subfamily. Transcript levels for this gene were significantly up-regulated when the cells were grown on low CO2. The cia8 mutant exhibited reduced growth and reduced affinity for Ci when grown in limiting CO2 conditions. [CIA8] (Mus musculus) PubMed

 21037.

Integration host factor is important for biofilm formation. [InfA], [InfB] (Mus musculus) PubMed

 21038.

The study presents a detailed analysis of the structural and thermodynamic effects governing the formation and stability of RAd20, an evolutionarily conserved protein assembly. Most of the stabilization effect reflected a small portion of the Rad50 hook domain surrounding the Zn2+ binding motif. [Rad50] (Mus musculus) PubMed

 21039.

Immunolocalization of A.aegypti aquaporin 5 (AaAQP5) revealed expression by Malpighian tubule principal cells of the larvae, with localization to both the apical and basolateral membranes. Knockdown of AaAQP5 with double-stranded RNA decreased larval survival, reduced rates of fluid, K(+) and Na(+) secretion by the Malpighian tubules, and reduced Cl(-) concentrations in the hemolymph.[AQP5] (Mus musculus) PubMed

 21040.

The X-ray crystal structure of RNA polymerase reveals a a unique mechanism for extending RNA within the transcription initiation complex. [RNA polymerase] (Mus musculus) PubMed

 21041.

characterization of a novel nicotinamide mononucleotide adenylyltransferase from Thermus thermophilus HB8 [NMNAT] (Mus musculus) PubMed

 21042.

Cas9/guide RNA binding to protospacer adjacent motif (PAM) favors separation of a few PAM-proximal protospacer base pairs allowing initial target interrogation by guide RNA [CRISPR-associated 9 (Cas9) endonuclease] (Mus musculus) PubMed

 21043.

the gene cluster for the cyanogenic glucoside dhurrin in Sorghum bicolor additionally contains a gene, SbMATE2, encoding a transporter of the multidrug and toxic compound extrusion (MATE) family, which is co-expressed with the biosynthetic genes. (Mus musculus) PubMed

 21044.

overexpression of GFP-LdGDI:WT enhances the lysosomal targeting of internalized hemoglobin and the secretion of gp63 in the parasites possibly by triggering Rab cycle. This is the first demonstration of a single GDI ubiquitously regulating both endocytic and secretory pathways in Leishmania. (Mus musculus) PubMed

 21045.

Enrofloxacin Permeation Pathways across the Porin OmpC [OmpC] (Mus musculus) PubMed

 21046.

Streptococcal heme binding protein (Shp) promotes virulence and contributes to the pathogenesis of group A Streptococcus infection. [Shp] (Mus musculus) PubMed

 21047.

oxR binds to the same sequence to activate the transcription of soxB and soxC. Sarcosine utilization was abolished in soxB and soxR mutants, suggesting that the sox locus is essential for sarcosine utilization (Mus musculus) PubMed

 21048.

Rht24 on chromosome 6A was identified as the major QTL for plant height in the winter wheat population 'Solitar x Bussard'. Rht24 allows to substantially reduce plant height without reducing Fusarium head blight resistance. (Mus musculus) PubMed

 21049.

Data from proteomic studies using biochemical membrane protein enrichment suggest that E coli genome contains a previously undetected/non-annotated small open reading frame for heat shock protein GndA (36-55 amino acids in length); gene locus diagram indicates stop codon of GndA is located downstream of a frame-shifted sequence within the annotated gnd gene. [GndA, small heat shock protein GndA] (Mus musculus) PubMed

 21050.

we characterized a novel 63.8kDa subtilisin-like protease NbSLP2 with a predicted transmembrane domain from Microsporidia, Nosema bombycis (Mus musculus) PubMed

 21051.

the auxin transporter-like protein 3 gene ns plays an important role in cucumber fruit spine development [ns] (Mus musculus) PubMed

 21052.

Gh_D03G0922 is likely the candidate gene for plant height in cotton [Gh_D03G0922] (Mus musculus) PubMed

 21053.

crystal structure of Thermus thermophilus RodA at a resolution of 2.9 A, determined using evolutionary covariance-based fold prediction to enable molecular replacement [peptidoglycan polymerase RodA] (Mus musculus) PubMed

 21054.

Data show that TaRIM1 encodes a R2R3-MYB transcription factor with transcription-activation activity: [RIM1] (Mus musculus) PubMed

 21055.

the promotion of apoptosis by human cytomegalovirusmiRUS45p in cells was specifically mediated via inhibition of PAK2 expression.[miRUS45p] (Mus musculus) PubMed

 21056.

This study performed are MD simulations on the recent glutamate transporter homologue GltTk structure and showed that the problem with the Na2 site arises from using an inadequate partial charge for S atom. When methionine is appropriately parametrized, both the position and the binding free energy of Na(+) at the Na2 site can be reproduced in good agreement with the experimental data. [GltTk] (Mus musculus) PubMed

 21057.

Aspergillus fumigatus egtA (AFUA_2G15650) encodes a trimodular enzyme with a role in Ergothioneine biosynthesis in this opportunistic pathogen [egtA] (Mus musculus) PubMed

 21058.

sepA is part of the AggR regulon; AggR is a positive regulator of sepA [sepA] (Mus musculus) PubMed

 21059.

PCV2 ORF4 protein contains an N-terminal amphipathic alpha-helix of 30 amino acid residues that targets viral protein ORF4 to the mitochondria, showing that viral protein ORF4 is a mitochondrial targeting protein and that viral protein ORF4 triggers caspase-dependent endogenous apoptosis by binding to ANT3. [ORF4] (Mus musculus) PubMed

 21060.

Overall, mutations in the ramR and tet(A) efflux genes constituted the major tigecycline resistance mechanisms among the studied tigecycline- and carbapenem-resistant Klebsiella pneumoniae isolates. [ramR] [tet(A)] (Mus musculus) PubMed

 21061.

Bph32 may inhibit feeding in brown planthopper.[Bph32] (Mus musculus) PubMed

 21062.

Here, the authors show that a new gene, named fosA7, confers resistance to fosfomycin. [fosA7] (Mus musculus) PubMed

 21063.

The Tmloop of Cel5A, a cellulase/mannanase from T. maritime, enhances GH5 enzyme promiscuity and plays a role in catalysis. This loop of GH5 serves for for mannan recognition and catalysis. Weakening the hydrophobic environment near the loop can also enhance the enzyme catalytic rate. Cel5A. (Mus musculus) PubMed

 21064.

Mutation of the amino acid residues in IN C-terminal domain interacting with target DNA reduced both IN enzymatic activities in vitro and viral productions in infected cells. [IN] (Mus musculus) PubMed

 21065.

RamR in S. Typhi neither repressed the expression of ramA, nor affected the bacterial resistance to ampicillin. In summary, RamR is not the repressor of RamA in S. Typhi, which is different from its role in other bacteria, such as S. Typhimurium and K. pneumoniae. (Mus musculus) PubMed

 21066.

Study showed two genes encoding L-LDH (ldhL1 and ldhL2) were annotated from the whole-genome sequence of B. coagulans DSM1. Also, ldhL1 was found to be crucial for L-lactic acid production and NADH balance in B. coagulans DSM1. [ldhL1 and ldhL2] (Mus musculus) PubMed

 21067.

The crystal structure of cleaved Serp-1 was determined to 2.5 A resolution and reveals a classical serpin structure with potential for serpin-derived reactive center loop peptides to bind and inhibit mammalian serpins, plasminogen activator inhibitor 1 (PAI-1), anti-thrombin III (ATIII), and alpha-1 antitrypsin (A1AT), and target proteases. [Serp-1] (Mus musculus) PubMed

 21068.

gene encodes a genuine and novel mating factor of A. fumigatus (MAT1-2-4) (Mus musculus) PubMed

 21069.

The trimethylamine N-oxide (TMAO) reductase TorA is a monomeric, bis-molybdopterin guanine dinucleotide cofactor-containing enzyme that belongs to the dimethyl sulfoxide reductase family of molybdoenzymes. Higher trimethylamine N-oxide reductase activities for TorA were obtained when using molybdenum cofactors sources containing a sulfido ligand at the molybdenum atom. [TorA] (Mus musculus) PubMed

 21070.

The goal of this research is to determine the residues that contribute to the activity of DNA Polymerase III alpha subunit. Six previously unidentified residues, R362, D405, K553, Y686, E688, and H760, are each essential to DNA Polymerase III alpha activity; three additional residues, Y340, R390, and K758, play important roles in activity. [DNA Polymerase III alpha] (Mus musculus) PubMed

 21071.

The the 2-dehydropantoate 2-reductase domain-containing proteins may have a similar function in glucan and/or mannan layer assembly. (2-dehydropantoate 2-reductase) (Mus musculus) PubMed

 21072.

Silencing of DND1 led to reduced susceptibility to Botrytis (DND1) (Mus musculus) PubMed

 21073.

Here, the authors describe the regulation of capsular polysaccharide, one of the most important pneumococcal virulence factor by a GntR family regulator, CpsR.[CspR] (Mus musculus) PubMed

 21074.

RNA sequencing (RNA-seq) was performed on wild-type (WT) and ifc ovaries that were collected after carpel fusion defects could be morphologically distinguished. In total, 877 differentially expressed genes were identified.[ifc] (Mus musculus) PubMed

 21075.

In this study the authors demonstrate that Hfq is essential for virulence in mice and influences production of surface pathogenicity factors, in particular lipopolysaccharide and adhesins mediating interaction with host tissue. (Mus musculus) PubMed

 21076.

HMGA1P7 mRNA sustains the H19 and Igf2 overexpression by acting as miRNA decoy. (Mus musculus) PubMed

 21077.

Study describes the molecular cloning and functional analysis of a new Atlastin homologous protein, Atlastin-n which was found to contain an N-terminal conserved GTPase domain and a coiled-coil middle domain. BmAtlastin-n is localized in the cytoplasm and enriched in silkworm midgut. Also, findings demonstrate that the protein plays an important role in BmNPV defense. [Atlastin-n] (Mus musculus) PubMed

 21078.

Corynebacterium glutamicum chorismate mutase requires the formation of a complex with DAHP synthase to achieve full activity, and both chorismate mutase and DAHP synthase are feedback regulated by aromatic amino acids binding to DAHP synthase. [chorismate mutase] (Mus musculus) PubMed

 21079.

This paper elucidates the thermodynamics and kinetics of leaf and branch compost cutinase conformational and colloidal stability. [leaf and branch compost cutinase ] (Mus musculus) PubMed

 21080.

L1 protease is crucial for viral accumulation and establishment of initial infection, whereas L2 is indispensable for infection of its natural citrus host. [L1, L2] (Mus musculus) PubMed

 21081.

MutT1 has a major role involving the hydrolysis of diadenosine polyphosphates [Mut1] (Mus musculus) PubMed

 21082.

study reports that the AbFhaB/FhaC system is involved in virulence when tested using invertebrate and vertebrate hosts; data suggest the potential role that this AbFhaB/FhaC secretion system could play in the pathobiology of A. baumannii [FhaB, FhaC]] (Mus musculus) PubMed

 21083.

alpha-l-rhamnosidase-encoding gene from Aspergillus oryzae was cloned and characterized [rhaA] (Mus musculus) PubMed

 21084.

The current study evaluates the delivery of dsRNA targeted to the sodium ion channel paralytic A (TcNav) gene in Tribolium castaneum as a viable means of controlling this insect pest.[TcNav] (Mus musculus) PubMed

 21085.

The auxiliary cluster in PqqE nearest the RS site (AuxI) is in the form of a 2Fe-2S cluster ligated by four cysteines, an Fe-S center not seen previously in other SPASM domain proteins; this assignment is further supported by Mossbauer and EPR spectroscopies. The second, more remote cluster (AuxII) is a 4Fe-4S center that is ligated by three cysteine residues and one aspartate residue. [PqqE] (Mus musculus) PubMed

 21086.

Laboratory evolution of alcohol dehydrogenase A produced enzyme variants with improved turnover numbers with a vicinal 1,2-diol and its corresponding hydroxyketone. Crystal structure and transient kinetics analysis aids in rationalizing the new functions of these variants. [alcohol dehydrogenase A] (Mus musculus) PubMed

 21087.

Glycine oxidase from Pseudoalteromonas luteoviolacea (PlGoxA) is a cysteine tryptophylquinone (CTQ)-dependent enzyme. The crystal structure of PlGoxA reveals that it is a homotetramer. It possesses an N-terminal domain with no close structural homologues in the Protein Data Bank. The active site is quite small because of intersubunit interactions, which may account for the observed cooperativy toward glycine. [PlGoxA] (Mus musculus) PubMed

 21088.

pyridoxal-5'-phosphate and GABA formed an external aldimine with GABR and trigger GabR-mediated transcription regulation.[GABR] (Mus musculus) PubMed

 21089.

AMPA glutamate receptor GluA is required for sensory-organ formation and morphogenesis.[GluA] (Mus musculus) PubMed

 21090.

CagA perturbs multiple host signaling pathways by interacting with the host signaling molecules, resulting in cytopathic effects and subsequent cell transformation. [CagA] [review] (Mus musculus) PubMed

 21091.

DsbA enhances the biofilm formation of V. cholerae by involving in the regulation of msha expression level. [msha. DsbA] (Mus musculus) PubMed

 21092.

Dual deletion of the kpsE and kpsD genes led to attenuation of virulence.[ kpsE, kpsD] (Mus musculus) PubMed

 21093.

Growth of mkl::Tn strain was attenuated, suggesting that mkl may play a role in the biosynthesis of oleic acid. (Mus musculus) PubMed

 21094.

CtcB is an essential activator in the chlortetracycline biosynthetic gene cluster. [CtcB] (Mus musculus) PubMed

 21095.

Furthermore, the authors show that cytoplasmic microtubules nucleation/anchoring is restricted at the level of recruitment of the gamma-tubulin complex receptor, Spc72, to spindle pole body (SPB), which is regulated by the polo-like kinase Cdc5.[Spc72, Cdc5] (Mus musculus) PubMed

 21096.

study identified a putative transcriptional factor Agseb1; Agseb1 has significant activity in different cellular pathways; the findings in this study may be generally applicable to the seb1 orthologs of other filamentous ascomycetes [Agseb1]. (Mus musculus) PubMed

 21097.

The Cys-His bridge as electron transfer conduit in the enzymatic catalysis of nitrite to nitric oxide by Sinorhizobium meliloti 2011 nitrite reductase was evaluated by site-directed mutagenesis, steady state kinetics, spectroscopy, and computational calculations. Changes in Cys-His bridge interrupt electron transfer between T1 and T2. The pH-dependent catalytic activity is related to modifications of the T1-T2 bridge. (Mus musculus) PubMed

 21098.

Conformational changes were observed in secondary and tertiary structure marked by a decrease in the helical and the sheet content in McFabZ structure upon the binding of 3 isoflavone inhibitors. These inhibitors are interacting with the active site of McFabZ and making contacts with catalytic and substrate binding tunnel residues. FabZ. (Mus musculus) PubMed

 21099.

Study demonstrate that the ligand binding domain (LBD) of CtpL does not binds inorganic phosphate (Pi) directly. However, CtpL mediates chemotaxis to low Pi concentrations. [CtpL] (Mus musculus) PubMed

 21100.

Rac2 played an essential role in acute liver injury induced by carbon tetrachloride.[Rac2] (Mus musculus) PubMed

 21101.

Human Ogg1 removes 7,8-dihydro-8-oxoguanine (OG) paired with cytosine (C) but is inactive toward the OG:adenine (A) pair. In contrast, Geobacillus stearothermophilus Formamidopyrimidine-DNA Glycosylase removes OG from OG:C pairs and also exhibits appreciable (although diminished) activity toward OG:A pairs. [Formamidopyrimidine-DNA Glycosylase ] (Mus musculus) PubMed

 21102.

MapZ is important for proper division plane selection.[Mapz] (Mus musculus) PubMed

 21103.

Study identifies two distinct antimicrobial peptides binding surfaces on SakDeltaN10 whose occupation would lead to either inhibition or promotion of its plasminogen activating properties. [Sak] (Mus musculus) PubMed

 21104.

study provides new evidence on the functional conservation and divergence of Skn7 orthologs among fungal organisms and indicates that VdSkn7 contributes to microsclerotial development, virulence and stress response of V. dahliae (Mus musculus) PubMed

 21105.

Results demonstrate that the Mtr protein, a mycothiol disulfide reductase, functions in corynebacterium glutamicum by protecting cells against oxidative stress. [Mtr] (Mus musculus) PubMed

 21106.

a novel P. falciparum rhoptry associated adhesin (PfRA) that mediates erythrocyte invasion through the sialic-acid dependent pathway, was identified.[PfRA] (Mus musculus) PubMed

 21107.

study highlights the importance of IglE in F. tularensis pathogenicity, and the contribution of the N-terminus to its funmction [IglE] (Mus musculus) PubMed

 21108.

Data suggest that LmrP exhibits a plasticity in proton interactions due to the intrinsic flexibility in the location of the key residues that are responsible for proton/drug exchange. This flexibility enables LmrP to rapidly evolve its polyspecificity through the acquisition of mutations while retaining proton/drug antiport activity. [LmrP] (Mus musculus) PubMed

 21109.

IPA1 is likely one of the long-speculated transcription factors that act with D53 to mediate the strigolactone-regulated tiller development in rice.[IPA1, D53] (Mus musculus) PubMed

 21110.

Both the dynamics simulations and experimental results show that the mutation of Phe71 in Type III Trypanosomal Protein Arginine Methyltransferase 7 (TbPRMT7) to Ile converts the enzyme from a type III methyltransferase into a mixed type I/II, that is, an enzyme that can now perform dimethylation. [Arginine Methyltransferase 7] (Mus musculus) PubMed

 21111.

point mutation in p53 structure, which diminishes p53:G-actin complexation results in mutant p53 altered subcellular localization.[G-actin] (Mus musculus) PubMed

 21112.

results provide a mechanistic understanding of the role of annexins in abiotic stress responses (EpANN) (Mus musculus) PubMed

 21113.

loss-of-function of OsOTUB1 is correlated with the accumulation of high levels of OsSPL14, resulting in the new plant type architecture.[OTUB1] (Mus musculus) PubMed

 21114.

study identified a novel protein family related to calcium metabolism and virulence; FlcA was identified as regulated by CrzA upon calcium stress and it is important for FAD metabolism [FlcA] (Mus musculus) PubMed

 21115.

In searching for mechanisms how TRIM14 exerts its antiviral function we found that TRIM14 interacted with HCV encoded non-structural protein NS5A and could strongly induce its degradation dependent on the NS5A1 subdomain. Interestingly extensive domain mapping analyses revealed that NS5A degradation was mediated by the highly conserved SPRY domain of TRIM14, which might involve the K48 ubiquitination pathway (Mus musculus) PubMed

 21116.

OsERS1 and OsETR2 could have different roles during rice plant submergence.[OsERS1, OsETR2] (Mus musculus) PubMed

 21117.

Study isolated a causal gene for the semi-dwarfism of sorghum, which has been widely introgressed into many cultivars, especially those of grain sorghum, using a QTL analysis and positional cloning. We concluded that Dw1 corresponds to Sobic.009g229800 and seems involved in cell proliferation activity in the internodes. [dw1] (Mus musculus) PubMed

 21118.

These results suggest that MPKK10.2 is a node involved in rice response to biotic and abiotic responses by functioning in the cross-point of two MAPK cascades leading to Xoc resistance and drought tolerance. [MPKK10.2] (Mus musculus) PubMed

 21119.

NDUFAF3, a homolog of the human NDUFAF3 gene, encodes for an assembly factor involved in complex I assembly. [NDUFAF3] (Mus musculus) PubMed

 21120.

The crystal structure of Avr2 reveals residues that are critical for its virulence activity.[Avr2] (Mus musculus) PubMed

 21121.

SoxO gene, encoding a glutathione disulfide reductase, is essential for tetrathionate oxidation in Advenella kashmirensis.[Advenella kashmirensis] (Mus musculus) PubMed

 21122.

This work identified a candidate gene for SCL1 that may play a role in leaf development.[SCL1] (Mus musculus) PubMed

 21123.

At high pH and only in the ferrous state, Lys42 competes with His46 for the iron coordination site. The reversible ligand switching has an apparent pKa of 9.3 and a Lys-ligated population of approximately 60% at the basic pH limit in the modified holoprotein. The switching rate was about 20-30 s(-1). Lys42-His46 competition and conformational rearrangement may be related to low bis-histidine ligation and more backbone ... (Mus musculus) PubMed

 21124.

The X-ray crystal structure of the dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase from Haemophilus influenzae (HiDapE) bound by the products of hydrolysis, succinic acid and l,l-DAP, was determined at 1.95 A. The catalytic domain rotates approximately 50 degrees and shifts approximately 10.1 A at the Zn atoms relative to the dimerization domain. Product-based transition-state modeling provided structura... (Mus musculus) PubMed

 21125.

The study presents the structure of LpxH which consists of two domains: a catalytic domain that is homologous to the metallophosphoesterases and a helical insertion domain. Lipid X was captured in the crevice between these two domains. These results reveal a large conformational change occurring at the lipid X binding site surface upon the binding/release of the product molecule. [LpxH] (Mus musculus) PubMed

 21126.

Here the authors identify porcine calreticulin expressed by swine intestinal cells as a host-specific receptor for Salmonella Choleraesuis FimH adhesin, suggesting that such an interaction may contribute to Salmonella Choleraesuis host specificity.[FimH] (Mus musculus) PubMed

 21127.

This study explores the effector function of BipC and reveals that actin interaction is conserved within the BipC/SipC/IpaC family of translocator/effector proteins.[BipC] (Mus musculus) PubMed

 21128.

ERN1 functions as a transcriptional regulator involved in the formation of infection threads and development of nodule primordia and may coordinate these two processes.[ERN1] (Mus musculus) PubMed

 21129.

These results demonstrate that M1 is a promising druggable target for the discovery of a completely new line of broad spectrum anti-IAV agents (Mus musculus) PubMed

 21130.

The structure of SpHMGR bound with its kinetically preferred NADPH cofactor suggests how NADPH-specific binding and recognition are achieved. The structure of HMG-CoA-bound SpHMGR reveals large, previously unknown conformational domain movements that may control HMGR substrate binding and enable cofactor exchange without intermediate release during the catalytic cycle. (Mus musculus) PubMed

 21131.

data provided in this study indicates that attenuated pathogenicity of ZtVf1 mutant is due to involvement of this gene in the regulation of both early and late stages of infection (ZtVf1) (Mus musculus) PubMed

 21132.

All rod-shaped Campylobacter jejuni transposons mutants and all rod-shaped laboratory, clinical and environmental Campylobacter jejuni and Campylobacter coli contained genetic changes within the pgp1 or pgp2 genes, which encode peptidoglycan modifying enzymes. [pgp1]; [pgp2] (Mus musculus) PubMed

 21133.

All rod-shaped Campylobacter jejuni transposons mutants and all rod-shaped laboratory, clinical and environmental Campylobacter jejuni and Campylobacter coli contained genetic changes within the pgp1 or pgp2 genes, which encode peptidoglycan modifying enzymes. [pgp1]; [pgp2] (Mus musculus) PubMed

 21134.

The structural and functional roles of disulfide bonds for HFBI in different interfacial contexts were determined by reducing its disulfides, blocking the free thiols, and examining the secondary structure, emulsification capability, hydrophobic surface wetting, and solution self-assembly. The disulfides were needed for stability, surfactant activity, and self-assembly. HFBI. (Mus musculus) PubMed

 21135.

Both component proteins of the Fe-nitrogenase system, the electron-delivery Fe protein (AnfH) plus the catalytic FeFe protein (AnfDGK), were purified. Under turnover conditions, N2 reduction is inhibited by H2. HD is formed when presented with N2 and D2 due to accumulation of 4 reducing equivalents as 2 metal-bound hydrides and 2 protons at the FeFe-cofactor, with activation by reductive elimination of H2. AnfH. AnfDGK. (Mus musculus) PubMed

 21136.

Biochemical and structural aspects of acetylation of HupB by Eis are reported. Rv1151c from Mtb deacetylated HupB in vitro and the deacetylation kinetics were determined. Activities of Eis and Rv1151c could regulate the acetylation status of HupB to remodel the mycobacterial chromosome in response to environmental changes. Eis. Rv1151c. (Mus musculus) PubMed

 21137.

A deletion of foot-and-mouth disease virus non-structural protein 3A reduced replication efficiency in bovine cells.[NS3A] (Mus musculus) PubMed

 21138.

Our results indicated that TaPHO2s involved in phosphorus uptake and translocation, and molecular engineering TaPHO2 shows potential in improving wheat yield with less phosphorus fertilizer (Mus musculus) PubMed

 21139.

FgVam7 interacts with FgVps39 and FgSso1 to form a unique complex, which is involved in vesicle trafficking and modulating the proper development of infection-related morphogenesis in F. graminearum.[FgVps39, FgVam7, FgSso1] (Mus musculus) PubMed

 21140.

The complete loss of GRA41 protein recapitulates the resistance phenotype to extracellular exposure to the calcium ionophore A23187 and importantly shows defects in calcium regulation and in the timing of egress. The findings support a connection between the tubulovesicular network and ion homeostasis within the parasite, and thus a novel role for the vacuole of this important pathogen. [GRA41] (Mus musculus) PubMed

 21141.

The study investigates the refolding modulations of MreB, the prokaryotic homologue of actin upon interaction with type I and type II chaperonins (GroEL/ES and TRiC chaperonin components respectivement). MreB structure is rearranged by a binding-induced expansion mechanism in TRiC, GroEL and GroES. [MreB] (Mus musculus) PubMed

 21142.

These results elucidate for the first time PNX1-hemichannels as potentially main extracellular translocation pathway for NDKs from an intracellular pathogen.[NDK] (Mus musculus) PubMed

 21143.

Crc plays an important role in growth and survival during infection.[Crc] (Mus musculus) PubMed

 21144.

Studies identified a point mutation in agrC leading to a single amino acid substitution (tyrosine to cysteine) at position 223, which contributed to differential virulence profiles in in vitro cell and tissue model systems, as well as in vivo in a murine tissue infection model. This specific AgrC variation was shown to determine the cytotoxic or colonizing infection profiles in infected tissue. [AgrC] (Mus musculus) PubMed

 21145.

The study shows the characterization of a novel paralog (CcEstA) of penicillin-binding proteins (PBPs) from C. crescentus CB15. CcEstA was shown to hydrolyze preferentially short-chain p-nitrophenyl esters, naphthyl esters, tertiary alcohol esters, and beta -lactam nitrocefin. In addition, CcEstA structure revealed the flexibility in the substrate-binding pocket. [EstA]. (Mus musculus) PubMed

 21146.

the identification of a novel brown adipocyte-enriched Long noncoding RNA (AK079912), and its nuclear localization, function and regulation, is reported.[Ak079912] (Mus musculus) PubMed

 21147.

Results identify a new binding site on TatC TM helix 6, adjacent to the polar cluster site. Each of TatA and TatB have the capacity to bind at both TatC sites depending on the activation state of the complex. In the resting-state system, TatB binds the polar cluster site, with TatA occupying the TM helix 6 site. Under activated by substrate overproduction, TatA and TatB switch binding sites. [tatA, TatB and TatC] (Mus musculus) PubMed

 21148.

liver receptor homolog (LRH)-1, not CYP19A1, is a direct functional target of miR-1275.[miR1275] (Mus musculus) PubMed

 21149.

WarA (PA4379) influences Pseudomonas aeruginosa O antigen modal distribution and interacts with the lipopolysaccharide biogenesis machinery. (Mus musculus) PubMed

 21150.

The sequence and phylogenetic analysis of Indian ORFV isolates in sheep and goats belonging to different geographical regions were analyzed on the basis of F1L gene. Sequence alignments revealed highly conserved C-terminus and heterogeneity of N-terminus region of F1L among all orfv studied. ORFV F1L resembled the topology of H3 protein from vaccinia virus with mixed beta/alpha folds and ligand binding specificity. [F1L] (Mus musculus) PubMed

 21151.

Here, the authors identified the telomere repeat-binding protein PfTRZ in the malaria parasite Plasmodium falciparum, a member of the Alveolate phylum for which telomere repeat-binding factors (TRZ) have not been described so far. PfTRZ lacks an MYB domain and binds telomere repeats via a C2H2-type zinc finger domain instead.[PfTRZ] (Mus musculus) PubMed

 21152.

a possible complex structural model by placing a Zn(2+)-containing dicluster ferredoxin of S. tokodaii into the large pocket of StOFOR2, providing insight into the electron transfer between the two redox proteins. (Mus musculus) PubMed

 21153.

cloning and characterization of the correct OsPAO6 cDNA with a length of 1,742 bp.[OsPAO6] (Mus musculus) PubMed

 21154.

the S. meliloti BacA has evolved toward a specific interaction with Medicago and highlights the limitations of using a single model system for the study of complex biological topics.[BacA] (Mus musculus) PubMed

 21155.

tbx61 data demonstrate that tbx6l and tbx16 genes function redundantly to direct tail somite development (Mus musculus) PubMed

 21156.

Structural study indicates that archaeol binds within two hydrophobic membrane-embedded grooves formed by the flexible transmembrane helix 5 (TM5), together with TM1 and TM4 of CDP-archaeol synthase (CDP-archaeol synthase). (Mus musculus) PubMed

 21157.

AdipoQ antisense (AS) Long noncoding RNA (lncRNA) transfer from nucleus to cytoplasm inhibits adipogenesis through formation of an AdipoQ AS lncRNA/AdipoQ mRNA duplex to suppress the translation of AdipoQ mRNA.[AdipoQ AS lncRNA] (Mus musculus) PubMed

 21158.

Two novel forms of the coiled-coil region of NSP4 from the bovine rotavirus strains MF66 and NCDV have been reported. [Nsp4] (Mus musculus) PubMed

 21159.

results demonstrate that TBP1 plays a significant role in regulating plant architecture via the brassinosteroid signaling pathway (Mus musculus) PubMed

 21160.

Aminofutalosine synthase (MqnE) is involved in the menaquinone biosynthetic pathway. This communication proposes a novel mechanism for this reaction involving the addition of the adenosyl radical to the substrate double bond to form a captodative radical followed by rearrangement and decarboxylation to form an aryl radical anion which is then oxidized by the [4Fe-4S](+2) cluster. [Aminofutalosine synthase] (Mus musculus) PubMed

 21161.

modulates leaf rolling by affecting cell wall formation, epidermis integrity and water homeostasis - [CLD1/SRL1] (Mus musculus) PubMed

 21162.

Through transient entry of the nicotinamide ring into the active site, the NADPH cofactor remodels the Dihydrofolate Reductase enzyme structure and the conformation of the tetrahydrofolate to form a weakly populated excited state that is poised for rapid product release. [Dihydrofolate Reductase] (Mus musculus) PubMed

 21163.

To improve the thermostability of (R)-selective amine transaminase (AT-ATA), this study used computer software Disulfide by Design and Modelling of Disulfide Bonds in Proteins to identify mutation sites where the disulfide bonds were most likely to form. Obtained were three stabilized mutants (N25C-A28C, R131C-D134C, M150C-M280C) from seven candidates by site-directed mutagenesis. [amine transaminase] (Mus musculus) PubMed

 21164.

four alleles of TaFT3-B1 and three alleles of TaTOE1-B1, were identified.[TaFT3-B1, TaTOE1-B1] (Mus musculus) PubMed

 21165.

These findings indicate a novel phosphorylation site in CIPK-AREB regulatory module for the abscissic acid signalling pathway.[CIPK, AREB] (Mus musculus) PubMed

 21166.

crystal structures of the apo enzyme and a binary Ago-guide complex; identified specific features of an Ago shedding light on the molecular mechanisms that drive DNA-guided DNA silencing [Ago Argonaute] (Mus musculus) PubMed

 21167.

Study presents the molecular cloning and characterization of two isoforms of Bmpop gene, Bmpop-a and Bmpop-b. A signal peptide was found in the sequence of Pop for the first time. BmPop-a showed the activity of prolyl oligopeptidase toward oligopeptides containing proline residue. BmPop-b isoform was highly expressed in the integument, and could be secreted into molting fluids. [popa & popb] (Mus musculus) PubMed

 21168.

Here the authors show that in the grass Brachypodium sopin1 mutants have organ initiation defects similar to Arabidopsis atpin1, while loss of PIN1 function in Brachypodium has little effect on organ initiation but alters stem growth.[sopin1] (Mus musculus) PubMed

 21169.

Mutant deficient in Mpk1p (mpk1Delta) showed severe growth retardation at both normal and high growth temperatures. (Mus musculus) PubMed

 21170.

nuclear Net1 is critical for zebrafish mesendoderm formation and Nodal signal transduction.[Nodal] (Mus musculus) PubMed

 21171.

AioR may regulate other cellular functions besides As(III) oxidation (AioR) (Mus musculus) PubMed

 21172.

The xray crystallographic structure of SuiB was determined and a model of its cross-linking activity was developed. A radical version of electrophilic aromatic substitution was suggested for the carbon-carbon bond formation during Lys-Trp cyclization. SuiB. (Mus musculus) PubMed

 21173.

The xray crystallographic structure of AgaB was determined and a model of its cross-linking activity was developed. A radical version of electrophilic aromatic substitution was suggested for the carbon-carbon bond formation during Lys-Trp cyclization. AgaB. (Mus musculus) PubMed

 21174.

The Stm1 stabilizes eEF2 on the 80 S ribosome in the GTP-bound form, independently of eEF2's diphthamide modification, a conserved post-translational modification at the tip of domain IV.(Stm1 protein, S cerevisiae) (Mus musculus) PubMed

 21175.

When bound to ferrichrome, the Ton box does not extend further into the periplasm, although the structural states sampled by the FhuA Ton box are altered. When bound to a soluble fragment of TonB, the TonB-FhuA complex remains heterogeneous and dynamic, indicating that TonB does not make strong, specific contacts with either the FhuA barrel or the core region of the transporter. [TonB, FhuA] (Mus musculus) PubMed

 21176.

LjNF-YA1 becomes indispensable downstream from the initial cortical cell divisions but prior to nodule differentiation, including cell enlargement and vascular bundle formation. Three affiliates of the SHORT INTERNODES/STYLISH transcription factor gene family, called STY1, STY2, and STY3, are demonstrated to be among likely direct targets of LjNF-YA1. [LjNF-YA1] (Mus musculus) PubMed

 21177.

mycolic acid flippase at the inner membrane and molecular target of BM212, a 1,5-diarylpyrrole compound [MmpL3] (Mus musculus) PubMed

 21178.

the prevalence of dhfr and dhps point mutations in P. falciparum isolates collected from asymptomatic pregnant women who had not received Sulfadoxine-pyrimethamine dhfr and dhps) (Mus musculus) PubMed

 21179.

CaAIPP1 interacted with and was ubiquitinated by CaAIRF1.[CaAIPP1, CaAIRF1] (Mus musculus) PubMed

 21180.

characterized Prli42, in detail, as a tail-anchored membrane protein that relays oxidative stress signals to the stressosome to activate the general stress-sensing pathway, the sigma B regulon [Prli42] (Mus musculus) PubMed

 21181.

non-redundant functions as the dimeric ABA receptor (Mus musculus) PubMed

 21182.

BnaA0639380D is a possible candidate gene for branch angle in oilseed rape.[BnaA0639380D] (Mus musculus) PubMed

 21183.

Sinorhizobium meliloti GhrA and Sinorhizobium meliloti GhrB show highest activity with glyoxylate and hydroxypyruvate, respectively; in addition, only GhrB reduces 2-keto-d-gluconate, and only GhrA reduces pyruvate (with low efficiency). [GhrA, GhrB] (Mus musculus) PubMed

 21184.

the genetic characterization of PanK1 and PanK2 in P. yoelii, is reported.[PanK1, PanK2] (Mus musculus) PubMed

 21185.

analysis of the RisA regulon by whole-genome transcriptomic analysis identifies the likely RisA kinase RisK; RisA phosphorylation is important; BvgR has a role in RisA activity in B. pertussis [RisK, RisA] (Mus musculus) PubMed

 21186.

Deep Cerebral microbleeds were more frequent (67%) and cognitive function was lower among subjects with cnm-positive S. mutans expressing collagen binding activity.[cnm] (Mus musculus) PubMed

 21187.

Mutation of residue 92 or 94 decreased viral-transcription and viral-infectivity levels, whereas mutation of residue 115 or 116 did not affect viral-infectivity in CRFK cells.[VP2] (Mus musculus) PubMed

 21188.

deletion of asp f3 rendered A. fumigatus avirulent in a mouse model of pulmonary aspergillosis.[Asp f3] (Mus musculus) PubMed

 21189.

East Asian CagA and Western CagA exploit distinct mechanisms for SHP2 deregulation.[CagA] (Mus musculus) PubMed

 21190.

crystal structure of TssK, a central component of the T6SS baseplate; show that it is composed of 3 domains, and establish the contribution of each domain to the interaction with TssK partners; study reveals the N-terminal domain of TssK is structurally homologous to the shoulder domain of phage receptor-binding proteins, and the C-terminal domain binds the membrane complex TssK] (Mus musculus) PubMed

 21191.

The host transcriptional response exhibited remarkable differences with and without the presence of the BipC protein.[BipC] (Mus musculus) PubMed

 21192.

Biochemical and computational studies in Vibrio cholerae CgtA (CgtAvc). Biochemically, a single amino acid substitution from Gly98 to Asp98 belonging to the Obg domain caused reduced GTPase activity of CgtAvc. The results from our comparative molecular dynamic simulations studies revealed that in silico amino acid substitution for Gly98Asp influenced the inter-domain movement between Obg domain and GTPase domain. [CgtA] (Mus musculus) PubMed

 21193.

In conclusion, we have shown that the A. flavus homeobox gene, hbx1, is required for normal vegetative growth and production of conidia and sclerotia. In addition, hbx1 is also required for the biosynthesis of aflatoxins, CPA and aflatrem[hbx1] (Mus musculus) PubMed

 21194.

The capacity to simultaneously bind phospholipids, Sec1p, multiple subunits of the exocyst, Cdc42p and the module for generating active Cdc42p identify Boi1p and Boi2p as essential mediators between exocytosis and polar growth.[Boi1, Boi2] (Mus musculus) PubMed

 21195.

in rice, miR159 positively regulates organ size, including stem, leaf, and grain size due to the promotion of cell division (microRNA 159) (Mus musculus) PubMed

 21196.

a single mutation in Ni-CE-P3 that is sufficient to inhibit MT-association and IFN-antagonist function of Ni-P3, and showed that this mutation alone attenuates the pathogenicity of Rabies virus.[P3] (Mus musculus) PubMed

 21197.

The identification of Cgl2 gene will enhance our understanding about its role in cabbage wax biosynthesis and lays a foundation for further study of cabbage wax metabolism (Cgl2) (Mus musculus) PubMed

 21198.

Effects of these sequence polymorphisms on the structural properties of the OmpF protein studied by computational analysis of its isoforms.The T148A polymorphism affected a loop located in the external vestibule of the OmpF channel, whereas IG(+)193 and IGIG(+)193 polymorphisms affected one of its beta-strands and suggested that polymorphism has moderate effect on the predisposition of OmpF and functional impications.[... (Mus musculus) PubMed

 21199.

The finding provides a role for the movement protein as a symptom determinant in broad bean wilt virus 2 and increases the understanding of the basis of molecular interactions between host plants and broad bean wilt virus 2. (Mus musculus) PubMed

 21200.

identifcation and characterization of a novel oocyst capsule-associated protein 93 (Cap93); posited that Cap93 is secreted from sporoblasts within the oocysts until sporozoites are formed; also, Cap93 constructs the interior of the oocyst capsule or part of the plasma membrane and affects sporozoite differentiation [Cap93] (Mus musculus) PubMed

 21201.

defined EspL from EPEC as the prototypic member of a family of T3SS cysteine protease effectors and identified the targets of EspL as host RHIM-containing proteins; EspL inactivated inflammatory, inflammasome and necroptotic signalling by cleaving within the RHIM, disrupting a range of host mucosal defence pathways [Espl] (Mus musculus) PubMed

 21202.

miR-277 plays a critical role in mosquito lipid metabolism and reproduction by targeting ilp7 and ilp8, and serves as a monitor to control ILP7 and ILP8 mRNA levels. (Mus musculus) PubMed

 21203.

Collectively, our data indicate that E2 is crucial in mediating the adaptation of C-strain to the rabbit, which requires synergistic contribution of E(rns) or E1. (Mus musculus) PubMed

 21204.

p53-2 was upregulated by dengue virus-induced ROS and functions to cope with ROS accumulation in DENV2-infected C6/36 cells [p53-2] (Mus musculus) PubMed

 21205.

These results suggest that MopB has pleiotropic functions in biofilm formation and twitching motility and is important for virulence of X. fastidiosa.[MopB] (Mus musculus) PubMed

 21206.

CaLRR51 acts as a positive regulator in the response of pepper to Ralstonia solanacearum infection.[CaLRR51] (Mus musculus) PubMed

 21207.

TraR has a role in directly regulating transcription initiation by mimicking the combined effects of the global regulators DksA and ppGpp [DksA] (Mus musculus) PubMed

 21208.

findings suggest that CNP058 is a potent inhibitor of apoptosis that is able to bind to BH3 domain peptides from a broad range of pro-death Bcl-2 proteins, and may play a key role in countering premature host apoptosis [CNP058] (Mus musculus) PubMed

 21209.

The ethylene-forming enzyme (EFE) converts 2-oxoglutarate (2OG) into ethylene plus three CO2 molecules while also catalyzing the C5 hydroxylation of l-arginine (l-Arg) driven by the oxidative decarboxylation of 2OG to form succinate and CO2. Here we report 11 X-ray crystal structures of EFE that provide insight into the mechanisms of these two reactions. [ethylene-forming enzyme] (Mus musculus) PubMed

 21210.

This study describes the discovery of an enantioselective radical dehalogenation pathway for alpha-bromoesters using flavin-dependent 'ene'-reductases. The 'ene'-reductase from G. oxydans (GluER) afforded the highest levels of enantioselectivity. [GluER] (Mus musculus) PubMed

 21211.

A novel MgrB variant in colistin susceptible strain was found. Elevated phoP and arn gene expressions and wild-type PmrB in all colistin resistant Klebsiella pneumoniae were detected. All strains lacked mcr-1.[Klebsiella pneumoniae ST258] (Mus musculus) PubMed

 21212.

Populus euphratica NHX3 was localized to the tonoplasts of Arabidopsis. PeNHX3 plays an important role in salt tolerance and Li(+) detoxification in plants. Transmembrane domain 11 controls the Na(+) and Li(+) transport activities of PeNHX3 in Arabidopsis. [NHX3] (Mus musculus) PubMed

 21213.

These effectors, in particular PpRxLR2, can be targeted for the development of biotechnology-based control strategies of P. parasitica diseases.[PpRxLR2] (Mus musculus) PubMed

 21214.

Targeted silencing of Ss-Rhs1 resulted in abnormal colony morphology and reduced virulence on host plants.[Ss-Rhs1] (Mus musculus) PubMed

 21215.

In the present study, S K-edge XAS is applied to experimentally measure the Fe-S bond covalency of the [Fe4S4] clusters in endonuclease III and MutY, both in the absence of and bound to DNA, and with and without solvent water. [MutY] (Mus musculus) PubMed

 21216.

MoRFX1 regulates development and pathogenicity by modulating the expression of genes involved in cell division and cell wall integrity.[MoRfx1] (Mus musculus) PubMed

 21217.

The studies offer important insights into the structural bases for allosteric site-to-active site communication and for beta-lactam mimicry of the peptidoglycan substrates, as foundational to the mechanistic understanding of emerging PBP2a resistance mutations. (penicillin-binding protein 2a) (Mus musculus) PubMed

 21218.

Effects of Resistance-Associated NS5A Mutations in Hepatitis C Virus on Viral Production and Susceptibility to Antiviral Reagents. (Mus musculus) PubMed

 21219.

With a genetically modified form of the flavoenzyme TrmFO as a suitable model system and using ultrafast fluorescence and absorption spectroscopy, this study characterizes its protonated precursor TyrOH(*+), and shows this species to have a distinct visible absorption band and a transition moment that it suggests to lie close to the phenol symmetry axis. [TrmFO] (Mus musculus) PubMed

 21220.

the type III secretion chaperone HpaB not only acts as an escort protein but also controls the recognition of translocation signals.[HpaB] (Mus musculus) PubMed

 21221.

ENDOR studies of the Pyruvate formate-lyase activating enzyme /[(13)S-adenosyl-l-methionine (SAM) complex show that the target sulfonium positioning varies with the cation, while the observation of an isotropic hyperfine coupling to the cation by ENDOR measurements establishes its intimate, SAM-mediated interaction with the cluster. [Pyruvate formate-lyase activating enzyme ] (Mus musculus) PubMed

 21222.

deletion of Caot protein (CP) amino acids 58 to 84 from the Wheat streak mosaic virus genome enhanced accumulation of CP and genomic RNA, altered CP-specific protein profiles, and caused severe symptom phenotypes in multiple cereal hosts.[CP] (Mus musculus) PubMed

 21223.

These results collectively suggest that CaHDZ27 functions as a positive regulator in pepper resistance against R. solanacearum.[CaHDZ27] (Mus musculus) PubMed

 21224.

293 host proteins were identified to associate with EspF. [EspF] (Mus musculus) PubMed

 21225.

Ydl121c (Exp1) is an ER protein that binds Pma1, is packaged into COPII vesicles, and whose deletion causes ER retention of Pma1. (Mus musculus) PubMed

 21226.

MDR1 expression is regulated by Mrr1.MDR1 role in fluconazole resistance.[MDR1] Mrr1 regulates MDR1 expression. [Mrr1] (Mus musculus) PubMed

 21227.

The aim of the present study was to optimize the expression of antiviral Cyanovirin-N homology gene found in the indigenous strain of Nostoc ellipsospourum LZN using Response Surface Methodology (RSM) and Protein Structure Analysis. (Mus musculus) PubMed

 21228.

Cel6C is a thermostable endoglucanase with activity on a variety of beta-glucans produced by an organism that struggles to grow above 30 degrees C [Cel6C] (Mus musculus) PubMed

 21229.

Findings indicate that SAV742 is a a novel AraC-family transcriptional regulator, and plays crucial roles in not only avermectin biosynthesis but also coordination of complex physiological processes in Streptomyces avermitilis. [SAV742] (Mus musculus) PubMed

 21230.

AVR-Pia is a cytoplasmic effector that is expressed at the onset of appressorial differentiation and is translocated to the biotrophic interfacial complex, and then into the host's cytoplasm.[Avr-Pia] (Mus musculus) PubMed

 21231.

The results suggest the importance of abiotic factors in LaeA regulation of patulin and other secondary metabolites that contribute to pathogenicity.[LaeA] (Mus musculus) PubMed

 21232.

FosA3 crystal structure revealed dynamic interconnectivity between its active sites and a loop structure that extends from the active site of each monomer and traverses the dimer interface.FosA3 role in fosfomycin resistance [FosA3] (Mus musculus) PubMed

 21233.

FosA crystal structure revealed dynamic interconnectivity between its active sites and a loop structure that extends from the active site of each monomer and traverses the dimer interface.FosA role in fosfomycin resistance.[FosA] (Mus musculus) PubMed

 21234.

Four novel mutations in the CrrB protein were identified at the sources of acquisition of high-level colistin resistance among carbapenemase-producing K. pneumoniae.CrrB role in drug resistance. [CrrB] (Mus musculus) PubMed

 21235.

Whib7 regulates genes to confer extreme antibiotic resistance.[Whib7] (Mus musculus) PubMed

 21236.

The role of whiB7 gene in antibiotic resistance.[whiB7] (Mus musculus) PubMed

 21237.

in this study, we demonstrated that the DENV2/16681 NS4B protein is capable of modulating the immune effectors that result from the activation of the unfolded protein response in insect cells. (Mus musculus) PubMed

 21238.

Srs2 also readily removes the recombination mediator Rad52 from RPA-ssDNA and, in doing so, promotes rapid redistribution of both Rad52 and RPA.[Srs2, RPA, Rad52] (Mus musculus) PubMed

 21239.

in E. coli, insulator sequences are preferentially encoded within sigma(54) promoters, suggesting an important regulatory role for these sequences in natural contexts.[sigma54] (Mus musculus) PubMed

 21240.

This paper presents a detailed description of expression, purification, and crystallization of a selenomethionyl lipase Lip8 from Yarrowia lipolytica. [Lip8] (Mus musculus) PubMed

 21241.

findings provide evidence that BphP1 mediates photoregulation of a switch from sessile to active swarming and contributes to movement to seeds in soil, survival and growth on leaves, and lesion development on bean pods [BphP1] (Mus musculus) PubMed

 21242.

The authors propose a mechanism where a DNA repair pathway activates a cascade leading to the increment of expression and phosphorylation of Trypanosoma cruzi DNA polymerase beta in response to oxidative damage.[DNA polymerase beta] (Mus musculus) PubMed

 21243.

the direct in vivo interaction between Turnip mosaic virus (TuMV) HCPro and the Arabidopsis homologue of SABP3, AtCA1, is reported.[Hcpro] (Mus musculus) PubMed

 21244.

crystal structure of ABC transporter [wzm & wzt] (Mus musculus) PubMed

 21245.

This work demonstrates that the production of OrfX contributes to limiting the host innate immune response by dampening the oxidative response of macrophages [OrfX]. (Mus musculus) PubMed

 21246.

During host-cell invasion, glutamine synthetase is required for the parasite to escape from the parasitophorous vacuole, a process sine qua non for the parasite to replicate and establish infection in host cells.[glutamine synthetase] (Mus musculus) PubMed

 21247.

study reports a novel noncanonical function of autophagy-related protein ATG18 in inheritance of the nonphotosynthetic plastid-like organelle apicoplast; TgATG18 interacts with 3'-phosphorylated PIPs, which guide their cellular localization in the parasite, which is essential for their function [ATG18] (Mus musculus) PubMed

 21248.

Genomic analysis of mutant clones generated by transposome mutagenesis suggests that hetero-resistance is linked with overexpression of the acrAB-tolC efflux pump. Transcriptional analysis further found that naturally elevated soxRS triggers the induction of the acrAB-tolC efflux pump proteins followed by the development of colistin hetero-resistance in E. asburiae and E. cloacae [soxR]. (Mus musculus) PubMed

 21249.

study reports a novel noncanonical function of autophagy-related protein ATG18 in inheritance of the nonphotosynthetic plastid-like organelle apicoplast; TgATG18 interacts with 3'-phosphorylated PIPs, which guide their cellular localization in the parasite, which is essential for their function [ATG18] (Mus musculus) PubMed

 21250.

A new formate dehydrogenase (FDH) from Clostridium ljungdahlii has been recently shown to possess activity in the reverse reaction: the mineralization of CO2 into formate. Biochemical and kinetic characterization of the enzyme revealed that this homologue also demonstrates activity toward CO2 reduction. [formate dehydrogenase] (Mus musculus) PubMed

 21251.

Genomic analysis of mutant clones generated by transposome mutagenesis suggests that hetero-resistance is linked with overexpression of the acrAB-tolC efflux pump. Transcriptional analysis further found that naturally elevated soxRS triggers the induction of the acrAB-tolC efflux pump proteins followed by the development of colistin hetero-resistance in E. asburiae and E. cloacae [soxR]. (Mus musculus) PubMed

 21252.

ectopic expression of rpfF in both transgenic tobacco and sweet orange also confers a reduction in disease severity incited by X. fastidiosa and reduces its colonization of those plants.[rpfF] (Mus musculus) PubMed

 21253.

These results support the possibility that Rhodococcus ruber OA1 aldehyde dehydrogenase plays the role of salicylaldehyde dehydrogenase (sALDH) in the oxidation of salicylaldehyde to salicylate.[sALDH] (Mus musculus) PubMed

 21254.

This study demonstrates that AbOmpA contributes to the antimicrobial resistance of A. baumannii through the OmpA-like domain [OmpA] (Mus musculus) PubMed

 21255.

findings suggest that elongation factor-Tu (EF-TU) functions as an adhesin. In summary, EF-Tu from G. anatis presents amyloid characteristics, is present in biofilms and could be relevant for the pathogenesis of G. anatis [EF-Tu]. (Mus musculus) PubMed

 21256.

Rotation activities of F1F0-ATPase promote localized nonequilibrium membrane fluctuations where the active proteins might be clustered. [F1F0-ATPase] (Mus musculus) PubMed

 21257.

These results suggest that the C-terminal region of HTLV-1 SU contains a novel site for direct binding of virus to the Nrp1 b1 domain. (Mus musculus) PubMed

 21258.

These results indicate that Reactive oxygen species derived from AoNoxA are essential for full virulence of A. oligospora in nematodes [NoxA]. (Mus musculus) PubMed

 21259.

The molecular weight of the enzyme was found to be 205 kDa by performing SDS-PAGE. While the enzyme exhibited the highest activity at 25 degrees C and pH 8.0, it was highly stable in alkaline media (pH 8.0-12.0) and retained 96% of its original activity at low temperatures (10-40 degrees C) for 24 hr. [alpha-amylase] (Mus musculus) PubMed

 21260.

dynamin is a molecular motor which would be involved in GLUT4 translocation by facilitating exocytosis [GLUT4] (Mus musculus) PubMed

 21261.

Transcriptome analysis reveals that Rta3 regulates expression of Bcr1 target genes involved in cell surface properties, adhesion, and hyphal growth. The authors show that rta3Delta/Delta mutant is biofilm-defective in a rat venous catheter model of infection and that BCR1 overexpression rescues this defect, indicating that Bcr1 functions downstream of Rta3 to mediate biofilm formation in Candida albicans. (Mus musculus) PubMed

 21262.

Catalytic activity of CYP109E1 towards the statin drug-precursor compactin and the prodrugs lovastatin and simvastatin as well as biotechnologically relevant terpene compounds including ionones, nootkatone, isolongifolen-9-one, damascones, and beta-damascenone was found in vitro.[CYP109E1] (Mus musculus) PubMed

 21263.

Logistic regression model analysis showed that the vacAi1 isoform gene in the infected strains and the severity of the diseases outcome were highly associated, causing severe gastric damage that may lead to gastric cancer. Conversely, cagA and genes were not associated with damage, while the dupA gene was associated significantly with non-severe clinical outcome.[cagA, vacA, dupA] (Mus musculus) PubMed

 21264.

The authors found that CsMAP34 and CsMASP1 expressions occurred in nine different tissues and were upregulated by bacterial challenge.[MAP34, MASP1] (Mus musculus) PubMed

 21265.

Thus, MaSte12 has critical roles in the pathogenicity of the entomopathogenic fungus Metarhizium acridum, and the study provides some explanations for the impairment of fungal virulence in DeltaMaSte12.[MaSte12] (Mus musculus) PubMed

 21266.

Data suggest that cytolysin and biofilm protein RbmC exhibit one or more beta-prism domains that target a similar repertoire of complex N-glycan receptors on mammalian cells (here, rabbit blood cells). (cytolysin; RbmC, V cholera biofilm protein-RbmC) (Mus musculus) PubMed

 21267.

monstrated that miR-330-5p is a negative regulator of differentiation by targeting BCAT2, and clarified the role of BCAT2 and miR-330-5p during preadipocyte differentiation[miR330, BCAT2] (Mus musculus) PubMed

 21268.

Together, these results show that the N-terminal domain of TbTim17 plays unique and essential roles for its sorting and assembly into the TbTim17 protein complex.[Tim17] (Mus musculus) PubMed

 21269.

In the presence of Wolbachia, specifically in female mosquitoes, the pelo protein is downregulated and its subcellular localization is altered.[pelo] (Mus musculus) PubMed

 21270.

Combination of an EGFR tyrosine kinase inhibitor and a NF-kappaB inhibitor effectively suppressed cetuximab-resistant HNSCC and interfering with the EGFR-LTbeta interaction reverses resistance. (Mus musculus) PubMed

 21271.

Study found interaction of OsIFL with metallothionein in the nucleus of cells. This interaction increased further throughout the nucleus in response to salinity stress. These results suggest that OsIFL is a key component of stress responsive machinery and through interaction with other specific proteins, OsIFL regulates cellular homeostasis and provide survival advantage to cells of diverse organisms. [IFL] (Mus musculus) PubMed

 21272.

Study describes novel effects of Bst1 acting as inositol deacylase of Glycosylphosphatidyl inositol anchored proteins (GPI-APs) in C. albicans, and facilitating cell wall anchorage of GPI-APs. Results suggest that abolishing inositol deacylation of GPI-APs in C. albicans not only impaired its invasion ability, but also exposed pathogen-associated molecular patterns recognized by host immune system. [Bst1] (Mus musculus) PubMed

 21273.

the functional importance of the association of FNR with the photosynthetic apparatus in Chlamydomonas reinhardtii, is reported.[FNR] (Mus musculus) PubMed

 21274.

H4K31 acetylation at the promoter correlates with, and perhaps directly regulates, gene expression in both Plasmodium falciparum and Toxoplasma gondii.[histone H4] (Mus musculus) PubMed

 21275.

Study provides evidence for TgATrx1's involvement in endoplasmic reticulum to apicoplast trafficking and TgATrx2 in the control of apicoplast gene expression components. [Atrx2] (Mus musculus) PubMed

 21276.

R148.3 is an signal sequence that modulates fat mass and longevity in an independent manner.[R148.3] (Mus musculus) PubMed

 21277.

Taken together, these findings suggest that VdMsn2 controls hyphal growth, microsclerotia formation, and virulence but does not significantly contribute to stress responses in Verticillium dahliae.[VdMsn2] (Mus musculus) PubMed

 21278.

This study indicates that PdSlt2 mitogen-activated protein (MAP) kinase is functionally preserved in Penicillium digitatum and highlights the relevant role of the PdSlt2 MAP kinase-mediated signalling pathway in regulating diverse genes crucial for infection and asexual reproduction.[PdSlt2] (Mus musculus) PubMed

 21279.

Silencing of GCN4 in Nicotiana benthamiana and Arabidopsis thaliana compromises host and nonhost disease resistance due to open stomata during pathogen infection.[GCN4] (Mus musculus) PubMed

 21280.

Based on in silico docking methods, five amino acids in glutamate synthase (Gln-467, His-1144, Asn-1147, Arg-1162, and Trp-676) likely constitute key binding residues in the interface of a glutamate synthase:ferredoxin complex.[GOGAT] (Mus musculus) PubMed

 21281.

Results show that Csp3 protein, a cytosolic member of a new family of bacterial copper storage proteins, is a tetrameric protein possessing a large number of Cys residues that point into the cores of its four-helix bundle monomers. Its expression allows copper to accumulate in bacteria which is able to safely maintain large quantities of this metal ion in their cytosol. [Csp3] (Mus musculus) PubMed

 21282.

Loss-of-function and gain-of-function experiments indicated that PGRP-L1 downregulates the induction of NOD-mediated pro-inflammatory cytokine expression.[PGRP-L1, NOD] (Mus musculus) PubMed

 21283.

These results support the hypothesis that CsrA affects both the Ysa and Ysc T3S systems in Yersinia enterocolitica. [CsrA] (Mus musculus) PubMed

 21284.

A serine protease with preference for fibrin protein was purified and characterized from Bacillus amyloliquefaciens MCC2606, isolated from dosa batter. The molecular weight of the CFR15-protease was estimated to be 32 kDa based on SDS-PAGE. The purified enzyme exhibited both fibrinolytic and fibrinogenolytic activity. [CFR15-protease] (Mus musculus) PubMed

 21285.

The authors show here that the SNARE protein Ykt6 is necessary for glycosome biogenesis and function in Trypanosoma brucei. RNAi-mediated depletion of Ykt6 in both the procyclic and bloodstream forms of T. brucei leads to mislocalization of glycosomal matrix proteins to the cytosol, pronounced reduction in glycosome number, and cell death.[Ykt6] (Mus musculus) PubMed

 21286.

Results show that iron ions stabilize the dodecameric form of Dps. The transmission electron microscopy data contradicted the assumption that the stabilizing effect is given by the optimal core size formed in the inner cavity of Dps. Modeling data of the interaction of FeO and FeO with Dps, only the binding sites with putative functionality were predicted and for FeO only. [dps] (Mus musculus) PubMed

 21287.

Ts-Hsp70 elicited protective immunity against T. spiralis infection was reduced in TLR2-/- and TLR4-/- mice correlating with the reduced humoral and cellular immune responses.[Hsp70] (Mus musculus) PubMed

 21288.

RNA interference (RNAi) of CYP6ER1 and transgenic expression of CYP6ER1 in Drosophila melanogaster both suggested that the expression of CYP6ER1 is sufficient to confer imidacloprid resistance.[CYP6ER1] (Mus musculus) PubMed

 21289.

TMS10 and TMA10L maintain male fertility under changing temperatures. [TMS10] , [TMA10L] (Mus musculus) PubMed

 21290.

Negative control of Candida albicans filamentation-associated gene expression by essential protein kinase gene KIN28 has been reported. [KIN28] (Mus musculus) PubMed

 21291.

crystal structure of the [CYP121(cYY)CN] ternary complex showed a rearrangement of the substrate in the active-site, when compared to the structure of the binary [CYP121(cYY)] complex (Mus musculus) PubMed

 21292.

The authors have determined the structures of the 80alpha and SaPI1 procapsids to near-atomic resolution by cryo-electron microscopy, and show that CpmB competes with the 80alpha scaffolding protein (SP) for a binding site on the capsid protein (CP), and works by altering the angle between capsomers.[CpmB, CP, SP] (Mus musculus) PubMed

 21293.

These data show that Borrelia burgdorferi OspC inhibits the classical and lectin complement pathways and competes with complement protein C2 for C4b binding.[OspC] (Mus musculus) PubMed

 21294.

PpzA plays an important role at the interface between iron starvation, regulation of secondary metabolite production, and pathogenicity in Aspergillus fumigatus.[PpzA] (Mus musculus) PubMed

 21295.

These data support that cytoplasmic histone H4 diacetylation weakens the Kap123-H4-nuclear localization signal interaction thereby facilitating histone Kap123-H3-dependent H3:H4/Asf1 complex nuclear translocation.[Kap123, histone H3, histone H4] (Mus musculus) PubMed

 21296.

findings demonstrate that FnBPs capture plasminogen (Plg) by a sophisticated activation mechanism involving fibrinogen (Fg) by S. aureus; these experiments favor a model where Fg-induced conformational changes in FnBPs promote their interaction with Plg [FnBPA, FnBPB] (Mus musculus) PubMed

 21297.

Study showed that AlgL negatively impacts alginate production through its enzymatic activity, and demonstrated that its deletion does not interfere with polymer length control, epimerization degree or stability of the biosynthesis complex, arguing that AlgL is a free periplasmic protein dispensable for alginate production. [algL] (Mus musculus) PubMed

 21298.

Data suggest that Uxt1 and Uxt2 are both transporters specific for xylose donor, UDP-xylose, although they exhibit distinct subcellular localization, expression patterns, and kinetic parameters; both isoforms also transport UDP-galactofuranose. (Uxt1, UDP-xylose transporter-1; Uxt2, UDP-xylose transporter-2) (Mus musculus) PubMed

 21299.

Structural and functional characterization of mercuric reductase (MerA) from Lysinibacillus sphaericus strain G1 has been presented. [MerA] (Mus musculus) PubMed

 21300.

Candida albicans cells lacking CaPPH3, CaPSY2 or CaPSY4, and Candida albicans cells carrying the Y33A mutation of CaPSY2, show increased virulence to mice. Therefore, protein phosphatase PP4 plays a negative role in regulating the DNA damage-induced filamentation and the virulence in Candida albicans.[CaPPH3, CaPSY2, CaPSY4] (Mus musculus) PubMed

 21301.

the up-regulated expression of osmic- and antioxidant-related genes in overexpressed plants indicated a role for TaPUB1 in plant salt tolerance.[TaPUB1] (Mus musculus) PubMed

 21302.

physiological roles of Oryza sativa phytochelatin synthase 1 (OsPCS1) in the distribution and detoxification of arsenic (As) and cadmium (Cd), are reported.[PCS] (Mus musculus) PubMed

 21303.

MdSnRK1.1 plays an important role in the ABA response, partially by controlling the stability of the MdCAIP1 protein.[MsSnRK1.1, MdCAIP1] (Mus musculus) PubMed

 21304.

The crystal structure of the Hsp-type protein SAV0551 and a co-crystal structure with glyoxylate were determined. SAV0551 has the distinctive characteristic structure of a holding chaperone, and is similar to E. coli Hsp31. [SAV0551] (Mus musculus) PubMed

 21305.

involvement in disease resistance, through interacting with MeATG8b and MeATG8e [GAPDH] (Mus musculus) PubMed

 21306.

Cctlr18 plays an important role in the immune response and provides basic information for investigating the mechanisms of fish tlr18. [Tlr18] (Mus musculus) PubMed

 21307.

KlpD is a bifunctional cyclodehydratase required for the formation of both the core cycles and the N-terminal amidine ring of Klebsazolicin. This study broadens the understanding of catalytic versatility of proteins of the YcaO superfamily, which may contribute to in vitro synthesis of new antibacterial compounds. [KlpD] (Mus musculus) PubMed

 21308.

Electron sweep across four b-hemes of cytochrome bc1 revealed by unusual paramagnetic properties of the Qi semiquinone intermediate has been reported. [cytochrome bc1] (Mus musculus) PubMed

 21309.

H. pylori CagA protein negatively regulates autophagy and promotes the inflammation in H. pylori infection, which is regulated by c-Met-PI3K/Akt-mTOR signaling pathway activation. [CagA] (Mus musculus) PubMed

 21310.

Sea anemone has a single Toll-like receptor that can function in pathogen detection, NF-kappaB signal transduction, and development. [TLR], [NF-kappaB] (Mus musculus) PubMed

 21311.

Edwardsiella ictaluri EiDeltahemR was safe and protective in catfish fingerlings, while EiDeltahemRDeltafrdADeltasdhC was much safer in catfish fry.[hemR] (Mus musculus) PubMed

 21312.

sawR (PA3133), that is highly overexpressed when P. aeruginosa is exposed to SAW. SawR is a putative transcription factor belonging to the TetR regulator family. When overexpressed sawR causes numerous phenotypes, including the accumulation of a brown pigment which we identified as pyomelanin.[sawR] (Mus musculus) PubMed

 21313.

The outer membrane protein OprF and the sigma factor SigX regulate antibiotic production in Pseudomonas fluorescens 2P24.[OprF] (Mus musculus) PubMed

 21314.

The results show that RpfR is a quorum sensing signal receptor that also functions as a cyclic-di-GMP sensor to control cell density and virulence. [RpfR] (Mus musculus) PubMed

 21315.

The loss-of-function alleles at DGS1-nivara(s) and DGS2-T65(s) were caused by weak or nonexpression of RPC4 and an absence of RPC4, respectively.[RPC4] (Mus musculus) PubMed

 21316.

expression of chemokine receptors LycCXCR2, LycCXCR3, and LycCXCR4 was elevated in the kidney, spleen, and particularly the liver of the large yellow croaker after challenge with Vibrio anguillarum and polyinosinic:polycytidylic acid (poly I:C).[cxcr2] (Mus musculus) PubMed

 21317.

acquisition of AmphiSoxE expression in the neural plate border led to neural crest cell emergence while duplication and divergence produced advantageous mutations in vertebrate homologues, promoting elaboration of neural crest traits. [SOXE] (Mus musculus) PubMed

 21318.

Zinc regulates ZNF1 gene expression.ZNF1 has 8 C2H2 zinc finger motifs.[ZNF1] (Mus musculus) PubMed

 21319.

MiR167 expression under Cd stress.NRAMP1b is a target of miR167.[Mir167] (Mus musculus) PubMed

 21320.

The interaction of On-CD28 with On-CD80/86 provides a costimulatory signals that possibly play an important role in T cell activation during Streptococcus agalactiae infection.[CD28] (Mus musculus) PubMed

 21321.

The expression levels of CsCRTL1and CsCRTL2 were highest in liver and spleen, respectively. After stimulation by Vibrio anguillarum and Streptococcus agalactiae, CsCRTL1 and CsCRTL2 were significantly up-regulated. [CRTL1,CRTL2] (Mus musculus) PubMed

 21322.

Mutating the nc-tgp1-short RNA polyadenylation signal attenuates induction of the tgp1 promoter during phosphate starvation (tgp1). (Mus musculus) PubMed

 21323.

Transcription upregulation of both CiLgals-a and Cigals-b, and CinPO2 genes in the vitellogenic follicular cells (FCs), with distinct cytolocalization of the proteins are shown. At vitellogenic stage, the CiLgals are localized in the FCs, in the oocyte cytoplasm, and close to the germinal vesicle (GV), whereas the CinPO2 was never identified in the GV.(gals-a,gals-b) (Mus musculus) PubMed

 21324.

Evidence that inflammation, cytotoxicity, and neutrophil infiltration is mediated by the bacterial beta-hemolysin/cytolysin, which also promotes the survival of S. agalactiae in the bladder (beta-hemolysin/cytolysin). (Mus musculus) PubMed

 21325.

The Serratia marcescens DeltachiR strain showed decreases in chitinase activity (4.5- to 25-fold decrease), confirming ChiR's role as a positive regulator of chitinase expression.[ChiR] (Mus musculus) PubMed

 21326.

In the current study, the authors show that RsbW and RsbV form a long-lived complex under transient stress treatment, resulting in high persistent expression of RsbV, RsbW and sigma(B) from mid-log phase to stationary phase.[RsbV] (Mus musculus) PubMed

 21327.

enzymatic characterization of a novel Xaa-Pro aminopeptidase XpmA from Aspergillus oryzae [XpmA] (Mus musculus) PubMed

 21328.

Data suggest lnc-leptin is among the most prominent lncRNAs expressed in adipocytes; lnc-leptin expression from an enhancer region upstream of leptin is sensitive to insulin and correlates to leptin expression across diverse pathophysiological conditions; induction of lnc-leptin is essential for adipogenesis; its presence is required for maintenance of leptin expression in adipocytes. (Lnclep, long non-coding RNA-leptin) (Mus musculus) PubMed

 21329.

AGP-L-1B haplotype association with kernel weight [AGP-L-1B] (Mus musculus) PubMed

 21330.

TMEM14B drives NP proliferation by increasing the phosphorylation and nuclear translocation of IQGAP1, which in turn promotes G1/S cell cycle transitions.[TMEM14b] (Mus musculus) PubMed

 21331.

GPCR-controlled membrane recruitment of negative regulator C2GAP1 locally inhibits Ras signaling for adaptation and long-range chemotaxis. [C2GAP1] (Mus musculus) PubMed

 21332.

Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase [DDOR] has been uncovered. [DDOR] (Mus musculus) PubMed

 21333.

Tongue sole rspo2l might play a role in immune responses after bacterial challenge, while the potential link with the WNT signaling pathway still requires further investigation. This is the first report about the involvement of rspondins in fish immune responses.[rspo2l] (Mus musculus) PubMed

 21334.

LjNPF8.6 achieves nitrate uptake in Xenopus laevis oocytes at both 0.5 and 30 mm external concentrations, and a possible role as a nitrate transporter in the control of Nitrogen-fixing nodule activity is discussed.[LjNPF8.6] (Mus musculus) PubMed

 21335.

the data demonstrate that MRB7260 is essential for productive protein-RNA interactions with RNA editing substrate binding complex during RNA editing. [MRB7260] (Mus musculus) PubMed

 21336.

in cyanobacteria, the CTD-like homolog are carotenoid donors to Helical Carotenoid Proteins.[OCP] (Mus musculus) PubMed

 21337.

The protein expression level of the heterogenous gene in genome-recombinant Listeria ivanovii -based vaccines is related to its inserted orientation in the bacterial genome, and a foreign gene inserted at this position of LIPI-1 will abolish Listeria virulence without affecting its growth.[LIPI-1] (Mus musculus) PubMed

 21338.

The results indicated that the TgGRA16 would be a promising vaccine candidate for further development of effective epitope-based vaccines against chronic T. gondii infection in mice. (Mus musculus) PubMed

 21339.

this is the first report of the effects of miR408-OsUCL8 in regulating rice photosynthesis and grain yield.[MiR408] (Mus musculus) PubMed

 21340.

Study shows the characterization of CYP701A26 which was found to exhibit ent-kaurene oxidase activity with substrate promiscuity and might be involved in maize gibberellin biosynthesis. [CYP701A26] (Mus musculus) PubMed

 21341.

These findings confirmed that HslUV AAA+ chaperone-Ntn peptidase complex of Leptospira interrogans contributes to leptospiral survival in hosts and transmission of leptospirosis.[HslU, HslV] (Mus musculus) PubMed

 21342.

In this study, the authors describe a novel secreted protein produced by Bacteroides fragilis strain 638R that mediated intraspecies antagonism. Using transposon mutagenesis and deletion mutation, they identified a gene encoding a eukaryotic-like ubiquitin protein (BfUbb) necessary for toxin activity against a subset of Bacteroides fragilis strains.[BfUbb] (Mus musculus) PubMed

 21343.

LRRK2 functions together with a second Parkinson's disease-associated gene, RAB7L1, within an evolutionarily conserved genetic module in diverse cellular contexts.[GLO-1] (Mus musculus) PubMed

 21344.

Study proposes a model in which Hsd3b2 regulates embryonic stem cells differentiation via modulating the activity of steroid hormones synthesis pathway. [Hsd3b2] (Mus musculus) PubMed

 21345.

Comparison of the mutant porphobilinogen deaminase structures with that of the wild-type enzyme shows that there are significant domain movements and suggests that the enzyme adopts ;open' and ;closed' conformations, potentially in response to substrate binding. [porphobilinogen deaminase] (Mus musculus) PubMed

 21346.

Colocation of the multiresistance gene cfr and the fosfomycin resistance gene fosD on a novel plasmid in Staphylococcus arlettae from a chicken farm in china has been reported. [fosD] (Mus musculus) PubMed

 21347.

An azole-resistant A. fumigatus strain with a 46-bp TR (TR46/Y121F/T289A) could be sensitised to azoles by deletion of srbA, encoding a direct regulator of cyp51A. SrbA loss did not affect colony growth or conidia production, but decreased expression of cyp51A. The srbA deletion strain showed hyper-susceptibility to medical azoles as well as azole fungicides, but its sensitivity to non-azole fungicides was unchanged. srbA (Mus musculus) PubMed

 21348.

PsrP adheres to extracellular DNA in the biofilm matrix and thus promotes pneumococcal biofilm formation.[PsrP] (Mus musculus) PubMed

 21349.

ZmXerico1 plays a role in the control of abscissic acid homeostasis.[ZmXerico1] (Mus musculus) PubMed

 21350.

this study revealed the novel role of OsWRKY53 as a regulator of rice Brassinosteroid signaling.[OsWRKY53] (Mus musculus) PubMed

 21351.

Knocking-out of the hcp gene had no influence on bacterial growth, but it could attenuate significantly the invasion and colonization of the bacterium. (Mus musculus) PubMed

 21352.

DRA0258 is an iron-binding protein and deletion of this gene would affect cellular iron transport system and reduce cellular antioxidant capability.[DRA0258] (Mus musculus) PubMed

 21353.

SsnA contributes to virulence in a zebrafish infection model, the adherence to HEp-2 cells, and the survival in pig blood. (Mus musculus) PubMed

 21354.

AbrB up-regulated the transcription of yvcPQ operon, then the increased YvcP strengthened the transcriptional acitivation of sporulation inhibitor gene kapD, and subsequently inhibited sporulation. [YvcP,YvcQ] (Mus musculus) PubMed

 21355.

STM14_3514 mutant shows increased virulence to mice.[STM14_3514] (Mus musculus) PubMed

 21356.

RGS2 was involved in regulation of vegetative growth, conidium production and germination, oxidative stress response, cell wall integrity and pathogenicity.[RSG2] (Mus musculus) PubMed

 21357.

identify a site in Bora whose phosphorylation by cyclin A/cdk1 is required for mitotic entry[bora] (Mus musculus) PubMed

 21358.

Results highlight the biological relevance of the hilD 3'UTR as a hub for post-transcriptional control of Salmonella invasion gene expression. (Mus musculus) PubMed

 21359.

Results show that Mycobacterium tuberculosis PtpA antagonizes TRIM27-promoted JNK/p38 MAPK pathway activation and cell apoptosis through competitively binding to the RING domain of TRIM27. (Mus musculus) PubMed

 21360.

The RNase T-mediated end turnover of the CCA sequence represents a means to deliver a tRNA to a repeated quality control performed by the CCA-adding enzyme. [RNase T and CCA-adding enzyme, Strain Escherichia coli CA244] (Mus musculus) PubMed

 21361.

The results strongly indicate that WLP2 protects chloroplast development from heat stress via a TRX-FLN regulatory module in rice. [WLP2] (Mus musculus) PubMed

 21362.

PC4 has a critical role in DNA repair pathway re-routing in DT40 cells [PC4] (Mus musculus) PubMed

 21363.

hese observations highlight remarkable properties of selected amino-acid changes at the Sir3-Sir4 interface that modulate the affinity of the two proteins.[Sir3, Sir4] (Mus musculus) PubMed

 21364.

The PhuS N-terminal alpha1/alpha2-helices that are cooperatively linked to the motions of the C-terminal domain also map to the PhuS:HemO interface. [PhuS] (Mus musculus) PubMed

 21365.

germ stem cell-rescuing activity appears to be tightly coupled with the ability to enhance Nos protein expression [TomO] (Mus musculus) PubMed

 21366.

findings demonstrate that the HTLV-1 latency-maintenance factor p30(II) induces the TP53-induced glycolysis and apoptosis regulator (TIGAR) and counters the oxidative stress, mitochondrial damage, and cytotoxicity caused by the viral oncoproteins Tax and HBZ [p30(II)]. (Mus musculus) PubMed

 21367.

Lsa21 is a potent TLR2 and TLR4 agonist that induces strong innate response and may play important role in Leptospira pathogenesis [Lsa21] (Mus musculus) PubMed

 21368.

Neutrophils are the primary target cells of pneumolysin, which causes neutrophil lysis.[pneumolysin] (Mus musculus) PubMed

 21369.

Mutagenesis of the FAE1 genes significantly changes fatty acid composition in seeds of Camelina sativa. (Mus musculus) PubMed

 21370.

structural basis for the sulfur transfer in SufS-SufU complex was revealed; a zinc-ligand exchange reaction upon SufS-SufU complexation provides a free thiol from Cys41 of SufU as a sulfur acceptor [SufU & SufS] (Mus musculus) PubMed

 21371.

The cytoplasmic effector PsAvh23 produced by the soybean pathogen Phytophthora sojae acts as a modulator of histone acetyltransferase (HAT) in plants.[Avh23] (Mus musculus) PubMed

 21372.

The structural analysis here supports a model wherein substrates must compete against a metastable interaction between XcpP in the assembly platform and the XcpQ secretin, wherein only structurally encoded features in the type 2 secretion system substrates compete well enough to disrupt XcpQ-XcpP for entry into the XcpQ chamber, for secretion across the outer membrane.[XcpQ, XcpP] (Mus musculus) PubMed

 21373.

The authors identified a serine-protease l,d-carboxypeptidase, NGO1274 (LdcA), as the enzyme responsible for converting cell wall tetrapeptide-stem peptidoglycan to released tripeptide-stem peptidoglycan.[LdcA] (Mus musculus) PubMed

 21374.

These observations indicate that the Sec21p/COPI transport complex has previously uncharacterized roles in modulating methotrexate stress.[Sec21] (Mus musculus) PubMed

 21375.

Recombinant Brugia malayi pepsin inhibitor (rBm33) modulates the host immune responses by skewing towards Th1 responses characterized by secretion of inflammatory molecules such as TNF-alpha, IL-6, nitric oxide (NO).[Bm33] (Mus musculus) PubMed

 21376.

D-Tagatose 3-epimerase was purified, crystallized and characterized; consistent with biochemical data, R118 forms a hydrogen bond with O4 of d-fructose [D-Tagatose 3-epimerase] (Mus musculus) PubMed

 21377.

Manipulation of the photosynthetic carbon reduction cycle can mitigate the effects of future high CO2 and high temperature environments on soybean yield, using the Synechococcus elongatus strain PCC7942 gene FBP1. (Mus musculus) PubMed

 21378.

UGT72AD1, UGT72AH1, and UGT72Z2 are flavonol-specific UGTs with different kinetic properties. In addition, the overexpression of UGT72AD1 and UGT72Z2 led to increased accumulation of flavonol rhamnosides in L. japonicus and Arabidopsis thaliana.[UGT72AD1, UGT72AH1, UGT72Z2] (Mus musculus) PubMed

 21379.

Rice (Oryza sativa) Phytochrome-Interacting Factor-Like1 (OsPIL1), a basic helix-loop-helix transcription factor, promotes Chl biosynthesis. The T-DNA insertion knockdown ospil1 mutant showed a pale-green phenotype when grown in a natural paddy field.[PIL1] (Mus musculus) PubMed

 21380.

Plants overexpressing osa-miR171b were less susceptible to RSV and virus symptoms were attenuated. Taken together, the results reveal that a reduction of osa-miR171b in rice stripe virus (RSV)-infected rice contributes to RSV symptoms, and provide more insight into the roles of osa-miR171b in rice. [miR171b] (Mus musculus) PubMed

 21381.

TaMYB19, TaMYB29, and TaMYB44 are co-regulators of wheat phloem-based defence and execute this function through crosstalk with the ethylene signalling pathway.[MYB19, MYB29, MYB44] (Mus musculus) PubMed

 21382.

Expression analysis suggested that the Rfn was highly expressed in flower buds and it was preferentially expressed in the tapetum and meiocytes during anther development. Further RNA gel blots and immunodetection suggested that the Rfn gene may play a complicated role in restoring the nap CMS.[Rfn] (Mus musculus) PubMed

 21383.

Heterologous expression and biochemical characterization of a novel thermostable Sclerotinia sclerotiorum GH45 endoglucanase in Pichia pastoris has been reported. [Endo2] (Mus musculus) PubMed

 21384.

Babesia bigemina HAP2 is expressed only in tick-infecting stages, and specific antibodies block zygote formation. [HAP2] (Mus musculus) PubMed

 21385.

we examined the expression profiles of three previously identified viral miRNAs (v-miRs) from the human herpesvirus (HHV) family, HSV-1 (miR-H1), KSHV (miR-K12-3-3p), and HCMV (miR-US4) in healthy and diseased periodontal tissues and observed increased levels of v-miRs in diseased tissues (Mus musculus) PubMed

 21386.

Identification of aaNAT5b as a spermine N-acetyltransferase in the mosquito, Aedes aegypti. (Mus musculus) PubMed

 21387.

M36 and M45 target caspase-8 and RIP3 pathways together to suppress this proinflammatory cell death. [M36. M45] (Mus musculus) PubMed

 21388.

These findings reveal an important cytomegalovirus mechanism for evading antiviral innate immunity through its encoded microRNA US25-1-5p by targeting transmembrane glycoprotein CD147.[US25-1-5p] (Mus musculus) PubMed

 21389.

D-Amino acid dehydrogenase from Proteus mirabilis JN458 was expressed and characterized for the first time, DAD was confirmed to be an alanine dehydrogenase. [DAD] (Mus musculus) PubMed

 21390.

This work reveals a dual role for the C-terminal domain of ParB as both a DNA binding and bridging interface, and highlights the dynamic nature of ParB networks in Bacillus subtilis.[ParB] (Mus musculus) PubMed

 21391.

the positive effect on Vmax derived from S288C FLO1 may only provide an advantage in haploids, or is dependent on strain-specific cis or trans effects.[FLO1] (Mus musculus) PubMed

 21392.

cyclin C-Cdk8p mediate AQY1 transcriptional repression by stimulating transcription factor proteolysis and preventing Set1p recruitment to the AQY1 locus.[Cdk8, AQY1, Set1p] (Mus musculus) PubMed

 21393.

ZmNST3/4 are master switches of the maize secondary wall biosynthesis process and provides new evidence that the secondary wall regulatory pathway is conserved in different plant species.[NST3,NST4] (Mus musculus) PubMed

 21394.

addition to functioning in the conversion of 7-HMC a to Chl a in senescent leaves, HCAR may play a critical role in protecting plants from high light-induced damage by preventing the accumulation of 7-HMC a and Pheo a in developing and mature leaves at the vegetative stage (Mus musculus) PubMed

 21395.

In a severe trauma model, sustained changes in terms of lung injury and inflammation are determined at day 3 post-trauma. Specifically, increased LTB4 in this porcine long-term model indicated a rapid inflammatory alteration both locally and systemically. The results support the concept of LTB4 as a biomarker for PC after severe trauma and lung contusion. (Mus musculus) PubMed

 21396.

a defective gamma/epsilon-AChR subunit switch, preferentially at synapses on slow fibers, precedes wasting of mutant soleus [acetylcholine receptor subunit gamma-ACHRG] (Mus musculus) PubMed

 21397.

negative regulation of OprD porin which leads to resistance against carbapenem.[OprD] (Mus musculus) PubMed

 21398.

Although a few isolates (11 of 71) from cattle had eae gene, they did not express phenotypically. This could be one of the reasons for not appearing of clinical symptoms in the hosts (Mus musculus) PubMed

 21399.

results demonstrates that SVBV P6 is a suppressor of RNA silencing, possibly acting at a upstream step for dsRNA generation [p6] (Mus musculus) PubMed

 21400.

APT1 deletion also affected synthesis of phosphatidylserine, phosphatidylethanolamine, inositolphosphoryl ceramide, glucosylceramide and ergosterylglycoside. These results reveal novel functions of Apt1 and are in agreement with the notion that this putative flippase plays an important role in the physiology of C. neoformans. (Mus musculus) PubMed

 21401.

Results show the highly expressed genes encoding heat-shock proteins, HSP82 and SSA4, potentially play an important role in helping S. cerevisiae KKU-VN8 cope with various stresses that occur during high-temperature fermentation, leading to higher ethanol production efficiency. [HSP82 & SSA4] (Mus musculus) PubMed

 21402.

Disruption of the sphR gene in P. aeruginosa markedly decreased the sphingomyelin-induced secretion of ceramidase, reduced hemolytic activity, and resulted in the loss of sphingomyelin-induced cerN (ceramidase) expression. Disruption of the sphR gene decreased the sphingomyelin-induced secretion of ceramidase, reduced hemolytic activity, and resulted in the loss of sphingomyelin-induced ceramidase expression. SphR. CerN. (Mus musculus) PubMed

 21403.

OsBVF1 is a novel plant-conserved factor involved in meiotic recombination in rice, providing a new insight into understanding of meiotic progression regulation.[BVF1] (Mus musculus) PubMed

 21404.

these results uncover the requirement of the coiled-coil and zinc-finger motifs for CIF1 function in cytokinesis and for CIF2 localization and stability, providing structural insights into the functional interplay between the two cytokinesis regulators. (Mus musculus) PubMed

 21405.

Identification of the seed binding regions required for interaction between GcvB and its mRNA targets (GccB). (Mus musculus) PubMed

 21406.

To better understand the role of cytoplasmic terminal regions, we characterized genetic suppressors that restore FurE-DeltaC-mediated uric acid transport.To our knowledge, this is the first case where not only the function, but also the specificity, of a eukaryotic transporter is regulated by its terminal cytoplasmic regions (Mus musculus) PubMed

 21407.

This study identified POB15 and POC16 as two proteins of the central core region, the distribution of which correlates with that of tubulin glutamylation; POB15 is an inner barrel protein within this region. Two poc16 mutants exhibit flagellar defects, indicating that POC16 is important for flagellum biogenesis. Human WDR90 is required for ciliogenesis, echoing the findings in Chlamydomonas. [POB15] (Mus musculus) PubMed

 21408.

Annexin A2 formed a slowly dissociating, high affinity complex with hepatitis C virus protein NS5B, decreasing its catalytic activity and affinity for the allosteric inhibitor filibuvir. The RNA binding of the two proteins was independent and AnxA2 and NS5B interacted with different RNAs in ternary complexes of AnxA2:NS5B:RNA, indicating specific preferences. (Mus musculus) PubMed

 21409.

P47 mediates mosquito immune evasion in both Plasmodium berghei (Pbs47) and Plasmodium falciparum (Pfs47), and has been shown to be important for optimal female gamete fertility . [P47][review] (Mus musculus) PubMed

 21410.

Small phosphatidate phosphatase (TtPAH2) of Tetrahymena possesses the minimal function of PAH protein family in respiration. [PAH2] (Mus musculus) PubMed

 21411.

ev21 is not required for the expression of late feathering in chickens (ev21). (Mus musculus) PubMed

 21412.

This study presents the characterization of an artificially maturated, putative sensory [FeFe] hydrogenase from Thermotoga maritima (HydS). This enzyme shows lower hydrogen conversion activity than prototypical [FeFe] hydrogenases and a reduced inhibition by CO. [HydS] (Mus musculus) PubMed

 21413.

These data suggest that SCD6 and RBP42, as occurs for their orthologues in other organisms, are involved in mRNA regulation, and probably they have a relevant role facing the stress conditions that Leishmania braziliensis encounters during insect-to-mammalian transmission.[RBP42] (Mus musculus) PubMed

 21414.

Rice only harbors one functional gene for DMA synthesis. In addition, the knock-down of OsDMAS1 significantly up-regulates the genes involved in Fe uptake and homeostasis. (Mus musculus) PubMed

 21415.

VviAGL11 relative expression was significantly higher in seeds at 2, 4, and 6 weeks after fruit set, whereas in the seedless grape its transcript levels were extremely low in all stages analyzed.[AGL11] (Mus musculus) PubMed

 21416.

Cyclic lipopeptides biosynthesis is regulated by nunF. [nunF] (Mus musculus) PubMed

 21417.

Electron Paramagnetic Resonance analysis suggested the presence of a 3Fe-4S type iron-sulfur cluster in the glucoside 3dehydrogenase (G3DH) catalytic subunit. [glucoside 3dehydrogenase] (Mus musculus) PubMed

 21418.

Therefore, PBP3SAL evolved in Salmonells typhimurium as a specialized peptidoglycan synthase promoting cell division in the acidic intraphagosomal environment.[PBP3SAL] (Mus musculus) PubMed

 21419.

Developed is a computational model, Protein Topology of Zoetic Loops to investigate the roles of OmpG extracellular loops implicated in gating. These results indicate that the gating equilibrium is primarily controlled by an electrostatic interaction network formed between the gating loop and charged residues in the lumen. [OmpG] (Mus musculus) PubMed

 21420.

MiR-145 silencing promotes bone repair of avascular necrosis of femoral head (ANFH) via upregulating VEGF, bFGF and inhibiting the bone cells apoptosis through Wnt/beta-catenin pathway [miR145] (Mus musculus) PubMed

 21421.

Dinucleotide repeat-length polymorphism in the 5'UTR region of the Csl gene was associated with tiller number in diverse wheat germplasm and linked to expression differences of Csl transcripts between near-isogenic lines.[csl] (Mus musculus) PubMed

 21422.

NHAD2 transporter apparently does not play any essential role in salt tolerance.[NHAD2] (Mus musculus) PubMed

 21423.

JAZ2 regulates stress responses possibly by participating in alpha-linolenic acid metabolism and jasmonate signaling.[JAZ2] (Mus musculus) PubMed

 21424.

CGRPinduced IL6 mRNA expression was mediated by mmu_circRNA_007893.[mmu_circRNA_007893] (Mus musculus) PubMed

 21425.

The present study provided evidence for the role of Hepatitis C virus (HCV) p7 in mitochondria, and may lead to the development of novel strategies for HCV therapy. [p7] (Mus musculus) PubMed

 21426.

Mcp, aer, cheB, and cheV are necessary for ND-01 adhesion and play key roles in the bacterial chemotaxis pathway. [Mcp, aer, cheB] (Mus musculus) PubMed

 21427.

Structure-guided mutational analysis establishes that the conserved sequence motifs in the linker and the domain-domain interface are essential for the function of Pa-Sua5 (Sua5). (Mus musculus) PubMed

 21428.

miR218 regulated the expression of 15HPGD during the differentiation of synovial mesenchymal stem cells into cartilage.[miR 218] (Mus musculus) PubMed

 21429.

Using the Forster resonance energy transfer response from a Trp-NADH donor-acceptor pair in T-jump studies of thermophilic alcohol dehydrogenase, this study reports microsecond protein motions that can be directly related to active site chemistry. [thermophilic alcohol dehydrogenase] (Mus musculus) PubMed

 21430.

Structural characterization, catalytic, kinetic and thermodynamic properties of Keratinase from Bacillus pumilus FH9 [Keratinase] (Mus musculus) PubMed

 21431.

Further investigations into the signals SsDRK1 responds to, and the interactions of upstream transmembrane hybrid histidine kinases with SsDRK1, are required to uncover novel targets for antifungal therapies (Mus musculus) PubMed

 21432.

vgrR-vgrS is a core downstream component of HpaR regulation, as overexpression of vgrR restored the phenotypic deficiencies caused by a hpaR mutation.[HpaR] (Mus musculus) PubMed

 21433.

the activation of cellulose biosynthesis in E. amylovora is a c-di-GMP-dependent process, through allosteric binding to the cellulose catalytic subunit BcsA. BcsZ is a key player in c-di-GMP activation of cellulose biosynthesis.[BcsA, BcsZ] (Mus musculus) PubMed

 21434.

NP, VP35, and VP24 are essential and sufficient to mediate nucleocapsid transport [NP, VP35, VP24- strain is not listed in the article] (Mus musculus) PubMed

 21435.

The degradation of ATF6 requires Herp1 or Herp2 and that Herp1 and Herp2 are redundant for ERAD-L of ATF6. (Herp1) (Mus musculus) PubMed

 21436.

ribavirin, an anti-viral drug, antagonized AphB function in animal models [AphB] (Mus musculus) PubMed

 21437.

In NS5B region, we detected A15G in 2.3% isolates (2/88), S96T in 1.1% isolates (1/88), and S282T in 20.7% isolates (17/88) and we detected I482L in 100% isolates (4/4), V494A in 50% isolates (2/4), and V499A in 100% isolates (4/4). (Mus musculus) PubMed

 21438.

variation in gO expression among independent strains may represent natural genotype variability present in vivo This may have important implications for virus-host interactions, such as immune recognition, and underscores the value of studying molecular mechanisms of replication using multiple HCMV strains. (Mus musculus) PubMed

 21439.

A thermostable alkaliphilic protein disulfide isomerase [PDI] from Bacillus subtilis DR8806 has been reported. [PDI] (Mus musculus) PubMed

 21440.

serum antibodies against HP-NAP represent a state of risk, which is further exacerbated in IL-4 -590 T carriers.[HP-NAP] (Mus musculus) PubMed

 21441.

The phosphorylation of EcRB1 was critical for its heterodimeric interaction with the USP1 protein and for binding to the ecdysone response element. [EcRB1] (Mus musculus) PubMed

 21442.

The invasion efficiency of Listeria monocytogenes strains with the 268-bp-long actA gene was 1.1-2.6-times lower than that of the strains with the 385-bp-long gene in normal and healthy cells.[actA] (Mus musculus) PubMed

 21443.

ApVKORo promotes disulfide bond formation in cell envelope, while the ApVKORi promotes disulfide bond formation in the cytoplasm. [ApVKORo, ApVKORi] (Mus musculus) PubMed

 21444.

EBV miR-BART6-3p inhibited the RIG-I-like receptor signaling and type I IFN response, thus facilitating EBV infection (Mus musculus) PubMed

 21445.

SpoIIIAG assembles into a large and stable 30-fold symmetric complex with a unique mushroom-like architecture/ [SpoIIIAG] (Mus musculus) PubMed

 21446.

FcpA together with FlaA2, produces coiling of periplasmic flagella of Leptospira, and the interaction between the sheath and core filament may be mediated by FcpA and FlaB1 [FlaA2, FcpA, FlaB2] (Mus musculus) PubMed

 21447.

the ST4, ST5 and ST6 RNAs are specifically and differentially up-regulated by MeJA, ET and SA, plant regulators also involved in the plant defence, pointing that ST4, ST5 and ST6 proteins might be involved in specific biotic interactions through different signalling pathways. (Mus musculus) PubMed

 21448.

new C. elegans models for Machado-Joseph disease, are proposed based on the expression of full-length ATXN3 in a limited number of neurons.[ATXN3] (Mus musculus) PubMed

 21449.

the product of the TvCyt2 gene is involved in secondary metabolite biosynthesis, which can increase antagonistic activity with phytopathogenic fungi and the capacity to promote plant growth.[TvCyt2] (Mus musculus) PubMed

 21450.

suggesting a crosstalk between B1R and B2R in tumor growing[Kinin B1 and B2 Receptors] (Mus musculus) PubMed

 21451.

regulates differentiation of floral meristems - [WHEAT FRIZZY PANICLE] and [SHAM RAMIFICATION 2] (Mus musculus) PubMed

 21452.

complementation analyses demonstrated the important role of copA for copper tolerance in E. amylovora, not only in vitro, but also in inoculated pear shoots.[copA] (Mus musculus) PubMed

 21453.

ZF domain of Nsp1alpha stimulates the secretion of CD83, which in turn inhibits MoDC function. Our study provides new insights into the mechanisms of immune suppression by PRRSV. (Mus musculus) PubMed

 21454.

Those results suggested that proteolysis by midgut proteases was associated with the insecticidal toxicity of Vip3Aa against S. exigua. It also revealed that trypsin played an important role in the formation of Vip3Aa activated toxin (Mus musculus) PubMed

 21455.

eccB4 encodes a core structural element of the type VII secretion system ESX-4. A deletion mutant of eccB4 was less efficient at blocking phagosomal acidification than its parental strain. [eccB4] (Mus musculus) PubMed

 21456.

These results provide evidence for a model where heterotopic ossification is triggered by inflammation but becomes "self-propagating" by a process that requires Activin A.[Activin A] (Mus musculus) PubMed

 21457.

polar localization dynamics of the serine chemoreceptor protein Tsr in Escherichia coli [Tsr] (Mus musculus) PubMed

 21458.

these data suggest that DSB repair mechanisms are impaired not only by Tax but also by HBZ and show that HBZ expression may significantly contribute to the accumulation of chromosomal abnormalities during HTLV-1-mediated oncogenesis. (Mus musculus) PubMed

 21459.

RipAY activity may constitute a novel and powerful virulence strategy employed by R. solanacearum to suppress immune responses and potentially alter general redox signalling in host cells.[RipAY] (Mus musculus) PubMed

 21460.

in E. coli cells chromosome over-replication signals CedA to recruit rpoB to specific DNA site(s), which initiates transcription of cell division regulatory elements.[CedA, rpoB] (Mus musculus) PubMed

 21461.

Pm-miR319a indirectly regulates the development of pistils by regulating its target gene Pm-TCP4 (miR319a). (Mus musculus) PubMed

 21462.

There was a significant increase in the salivary presence of the miR-16, miR-191 and miR-223 at 6th and 18th-19th days than the 0 day (estrus), 10th day and the following consecutive estrus day. [miR-16] [miR-191 ] [miR-223] (Mus musculus) PubMed

 21463.

Salicylaldehyde synthase (SAS) catalyzes non-oxidative C2-side chain cleavage of 2-coumaric acid to form salicylaldehyde (SALD) in the presence of a reducing agent such as cysteine. The side chain cleavage mechanism was found to be very similar to that of salicylaldehyde synthase activity from tobacco.[salicylaldehyde synthase] (Mus musculus) PubMed

 21464.

MdNAC029 was responsive to low-temperature treatment, and over-expression of MdNAC029 reduced cold tolerance in apple calli and Arabidopsis. Furthermore, EMSA assays and transient expression assays demonstrated that MdNAC029 directly repressed the expression of MdCBF1 and MdCBF4 by binding to their promoters.[NAC029,CBF4] (Mus musculus) PubMed

 21465.

there is long-range inter-domain communication between distal copper sites that contribute to overall Fet3p stability.[Fet3p] (Mus musculus) PubMed

 21466.

Dek39 encodes an E sub-class PPR protein that is involved in RNA editing of multiple sites and is necessary for seed development of maize.[Dek39] (Mus musculus) PubMed

 21467.

miR528 negatively regulates viral resistance in rice by cleaving L-ascorbate oxidase (AO) (miR528) (Mus musculus) PubMed

 21468.

e confirmed NTC-sat2 selection could work with the hygromycin B selection system simultaneously. Thus, the new NTC-Sat2 system can act as a useful dominant marker for gene transfer and genome editing in C. elegans. (Mus musculus) PubMed

 21469.

Sequence analysis showed that LiMTAP shared higher identity rates with the Trypanosoma brucei (TbMTAP) and the human (huMTAP) homologs; the 3D model of LiMTAP showed an additional alpha-helix, at the C terminal extremity; study highlighted significant structural differences. (Mus musculus) PubMed

 21470.

The findings indicate that LjAPN1 is required for the development and persistence of functional (nitrogen-fixing) symbiosis in a rhizobial strain-dependent manner, and thus determines compatibility between Mesorhizobium loti and Lotus japonicus at the level of nitrogen fixation. [LjAPN1] (Mus musculus) PubMed

 21471.

A monoUb-binding interface is located within the C terminus but unlikely to be associated with the four-helix bundle of ExoU. [ExoU] (Mus musculus) PubMed

 21472.

The unusual open-close kinetics of quiescin sulfhydryl oxidase (QSOX)results from slow sampling of an ensemble of disordered domain orientations. [QSOX] (Mus musculus) PubMed

 21473.

the current study reveals the capability of F17A-MF59 as a potential vaccine candidate against pathogenic E. coli causing mastitis in dairy animals. (Mus musculus) PubMed

 21474.

We showed that CK1.1 is a low-abundance protein present in promastigotes and in amastigotes. We demonstrated that CK1.1 is not essential for promastigote and axenic amastigote survival or for axenic amastigote differentiation, although it may have a role during stationary phase (Mus musculus) PubMed

 21475.

A hypothesis for how OsGSK5 action could fit into a signaling model that integrates salinity stress to changes in starch metabolism, is reported.[OsGSK5] (Mus musculus) PubMed

 21476.

ELF1 acts in a rice brassinosteroid signaling pathway different from that initiated by OsBRI1.[ELF1, OsBRI1] (Mus musculus) PubMed

 21477.

human (hs) TSase and its contrasts and the similarities to the well-studied Escherichia coli (ec) TSase [Tsase] (Mus musculus) PubMed

 21478.

high flexibility in a domain critical for circadian rhythm and RNA surveillance - [frequency-interacting RNA helicase] (Mus musculus) PubMed

 21479.

When the plasmids were electroporated into Shigella flexneri or they lost positive plasmids, the MICs of ciprofloxacin increased or decreased two- to eightfold for aac(6')-Ib-cr-positive plasmids and 16- to 32-fold for qnrS-positive plasmids. (Mus musculus) PubMed

 21480.

ZmPIF3 plays a major role in the abscisic acid (ABA) signaling pathway. In addition, digital gene expression (DGE) results further suggest that ZmPIF3 participates in the ABA signaling pathway and regulates stomatal aperture in rice. [ZmPIF3] (Mus musculus) PubMed

 21481.

Secreted Ta9 has therefore, not only the ability to stimulate CD8+ T cells, but also the potential to activate AP-1-driven transcription and contribute to T. annulata-induced leukocyte transformation (Mus musculus) PubMed

 21482.

K. oxytoca harboring a 16S rRNA methylase encoding gene ArmA in Japan. [Klebsiella oxytoca] [ArmA] (Mus musculus) PubMed

 21483.

These data suggest that pouMU1 might participate in regulating chicken muscle development and growth, and the findings offer new insight into the functions of sequence mutations in lncRNAs. (Mus musculus) PubMed

 21484.

The data reveal a mechanism in which rice plants govern Abscisic Acid (ABA)-dependant drought responsive gene expression by controlling the stability of OsbZIP23 by SUMO conjugation through manipulating specific SUMO protease levels. [OsbZIP23] (Mus musculus) PubMed

 21485.

MaGyp2 mutant had dramatically decreased tolerance to ultraviolet irradiation compared to wild type strain.[Metarhizium acridum] (Mus musculus) PubMed

 21486.

The findings suggest that ZmCHB101 affects gene expression by remodeling chromatin states and controls RNA Polymerase II (RNAPII) occupancies in maize under osmotic stress. [ZmCHB101]. (Mus musculus) PubMed

 21487.

This work is devoted to the ascertainment of serological cross-reactivity between OmpF porin from Yersinia pseudotuberculosis (YpOmpF) and human thyroid-stimulating hormone receptor (hTSHR).[OmpF] (Mus musculus) PubMed

 21488.

FleQ positively regulates flagella biosynthesis but negatively regulates the type VI secretion system in P. putida; this finding is important for understanding the function and regulation of the type VI secretion system [FleQ] (Mus musculus) PubMed

 21489.

AGO18b is a negative regulator of the determinacy of inflorescence and axillary meristems.[Ago18b] (Mus musculus) PubMed

 21490.

BnWRKY41-1 has a similar role with AtWRKY41 in regulating anthocyanin biosynthesis when overexpressed in A. thaliana.[BnWRKY41-1] (Mus musculus) PubMed

 21491.

The study suggested that PII protein regulates the synthesis of acetyl CoA and acetyl CoA carboxylase enzyme at the transcriptional level.[PII, acetyl CoA carboxylase] (Mus musculus) PubMed

 21492.

Findings reveal that an ehrlichial surface invasin, EtpE, not only triggers bacterial entry but also blocks ROS generation by host macrophages through its host cell receptor, DNase X. As ROS sensitivity is an Achilles' heel of this group of pathogens, understanding the mechanism by which E. chaffeensis rapidly blocks ROS generation suggests a new approach for developing effective anti-infective measures [EtpE]. (Mus musculus) PubMed

 21493.

Here, we establish that the disruption of an ovarian-tumor (OTU) family deubiquitinase,TgOTUD3A , in tachyzoites results in dysregulation of the mechanism controlling the selection of replication strategy in a subset of parasites [TgOTUD3A]. (Mus musculus) PubMed

 21494.

The disruption of hemA1, encoding the glutamyl-tRNA(Glu) reductase of the C5 pathway, was essential for cell growth and is used for heme synthesis. The disruption of hemA2 indicated that it encodes the 5-aminolevulinic acid synthase of the Shemin pathway, serving as a key enzyme for the synthesis of the precursor.{hemA1, hemA2] (Mus musculus) PubMed

 21495.

transgenic Nicotiana tabacum plants overexpressing GhTPS12 were generated, which produced relatively large amounts of (3S)-linalool.[GhTPS12] (Mus musculus) PubMed

 21496.

MiR-221 increased skeletal muscle satellite cells proliferation and decreased differentiation. [miR-221] (Mus musculus) PubMed

 21497.

a tight interaction between gibberellins (GA)- and cytokinins (CK)-signaling pathways, with DELLA1-mediated GA signaling regulating CRE1-dependent CK signaling critical for nodule initiation (DELLA1). (Mus musculus) PubMed

 21498.

The in vivo effect of a serine proteinase inhibitor (BTI-CMe) and a cysteine proteinase inhibitor (Hv-CPI2) from barley on the moth Tuta absoluta was examined: larvae fed on tomato transgenic plants co-expressing both proteinase inhibitors showed a notable reduction in weight.[CPI2] (Mus musculus) PubMed

 21499.

lcIL12A, lcIL16 and lcIL34 were constitutively expressed in all examined tissues, with significantly higher expression in spleen, liver and kidney. This was especially true for lcIL34 gene. Importantly, when challenged with polyinosinic:polycytidylic acid (poly I:C) and Vibrio anguillarum, the mRNA expressions of these interleukins were up-regulated in liver, spleen and kidney. [IL12A] (Mus musculus) PubMed

 21500.

Hierarchical roles of mitochondrial Papi and Zucchini in Bombyx germline piRNA biogenesis [Papi; Zucchini] (Mus musculus) PubMed

 21501.

These data suggest that bacterial SdhE proteins, and their mitochondrial homologs, are assembly chaperones that constrain the conformation of SdhA to facilitate efficient flavinylation while regulating succinate dehydrogenase activity for productive biogenesis of SQR.[SdhE; SdhA] (Mus musculus) PubMed

 21502.

Adenylate kinase substrate binding increases dramatically domain closing and opening times, making them as short as approximately 15 and approximately 45 micros.[ Adenylate kinase] (Mus musculus) PubMed

 21503.

TaHsfC2a-B is a transcriptional activator of heat protection genes and serves as a proactive mechanism for heat protection in developing wheat grains via the abscissic acid-mediated regulatory pathway.[TaHsfC2a] (Mus musculus) PubMed

 21504.

Map-based cloning revealed that MIT3 encodes a carotenoid isomerase (CRTISO), the key enzyme catalyzing the conversion from prolycopene to all-trans-lycopene in carotenoid biosynthesis.[MIT3] (Mus musculus) PubMed

 21505.

H3K27me3-modified sites were observed in 95 of the 109 up-regulated genes, and some of them were up-regulated in OsFIE2, OsCLF and OsEMF2b RNAi transgenic plants, and their H3K27me3 levels were reduced in emf2b.[EMF2b,CLF] (Mus musculus) PubMed

 21506.

The hsa1 mutant harbors a recessive mutation in a gene encoding fructokinase-like protein2 (FLN2); the mutation causes a premature stop codon and results in a severe albino phenotype, with defects in early chloroplast development.[FLN2] (Mus musculus) PubMed

 21507.

By comparing the proteomes of the asp23 mutant and its parent strain grown in the presence of gentamycin, it was shown that 22 and 21 proteins were significantly up- and downregulated, respectively . (Mus musculus) PubMed

 21508.

Distinctive profiles of aad-1 transcript and protein accumulation were observed when different regulatory elements were utilized in the constructs under study. The ZmUbi and the SCBV constructs showed the most consistent robust tolerance, while the melon actin construct provided the lowest level of tolerance compared to the other regulatory elements used in this study. [aad-1] (Mus musculus) PubMed

 21509.

By observing the data obtained from the isothermal titration calorimetry assay, both of the human proteins (KRCC1 and ZFAND6) were demonstrated to bind to their respective Toxoplasma gondii SAG1 and SAG2 proteins.[SAG1, SAG2] (Mus musculus) PubMed

 21510.

Analyses of the CsDIR16-expression patterns in the cucumber cultivars with the highest and lowest levels of Propamocarb (PM) residue, and transgenic validation indicated that CsDIR16 plays a positive role in reducing PM residues.[Dir16] (Mus musculus) PubMed

 21511.

Ectopic expression of MdY3IP1 triggered early-flowering and enhanced salt tolerance in Arabidopsis plants. MdY3IP1 controlled floral transition by accelerating sugar metabolism process in plant cells, thereby influencing the expression of flowering-associated genes. [Y3IP1] (Mus musculus) PubMed

 21512.

photoactivation and relaxation of OCP in the presence of copper were examined in this communication.[OCP] (Mus musculus) PubMed

 21513.

SAG2A differentially modulates IL-1beta expression in resistant and susceptible murine peritoneal macrophages cells. [SAG2A] (Mus musculus) PubMed

 21514.

OsTGA10, encoding a bZIP transcription factor, is a target of the MADS box protein OsMADS8, which is annotated as an E-class organ identity protein.[OsTGA10, OsMADS8] (Mus musculus) PubMed

 21515.

GW5 is a novel positive regulator of brassinosteroid signalling and a viable target for genetic manipulation to improve grain yield in rice and perhaps in other cereal crops as well. (Mus musculus) PubMed

 21516.

FlhB1 gene is essential for correct assembly of both constitutive polar flagellum and inducible lateral flagella.[FlhB1] (Mus musculus) PubMed

 21517.

The present study has uncovered how FlhF influences C. jejuni flagella biosynthesis, which will be helpful in understanding the C. jejuni flagella biosynthetic pathway and bacterial flagellation in general. [FlhF] (Mus musculus) PubMed

 21518.

High-resolution crystal structures were obtained for membrane integral Lnt. Thermal stability was measured by circular dichroism. The detergent-solubilized form possessed N-acylation activity. (Mus musculus) PubMed

 21519.

BS1 is an esterase that cleaves acetyl moieties from the xylan backbone at O-2 and O-3 positions of xylopyranosyl residues. BS1 thus plays an important role in the maintenance of proper acetylation level on the xylan backbone, which is crucial for secondary wall formation and patterning.[BS1] (Mus musculus) PubMed

 21520.

pol I proofreading exonuclease is the major function responsible for deoxyinosine lesion removal after endoV nicking both in vitro and in vivo. (gene pol I) (Mus musculus) PubMed

 21521.

Xa4, encoding a cell wall-associated kinase, improves multiple traits of agronomic importance without compromising grain yield by strengthening the cell wall via promoting cellulose synthesis and suppressing cell wall loosening. Strengthening of the cell wall by Xa4 enhances resistance to bacterial infection.[Xa4] (Mus musculus) PubMed

 21522.

he SHORTROOT pathway may coordinate the positioning of veins and stomata in monocot leaves.[SHR] (Mus musculus) PubMed

 21523.

the autophagy cargo receptor NBR1 suppresses viral accumulation by targeting the viral RNA silencing suppressor helper-component proteinase (HCpro), presumably in association with virus-induced RNA granules.[HCpro] (Mus musculus) PubMed

 21524.

he relationship between SBE dosage and the morphological architecture of heterogeneous starches, was investigated.[SBE] (Mus musculus) PubMed

 21525.

over-expression of OsMIR396d in rice results in semidwarf and increased leaf angle, a typical phenotype of brassinosteroid (BR) enhanced mutant.[OsMIR396d] (Mus musculus) PubMed

 21526.

OsIDD2 is negatively involved in SCW formation and other biological events by downregulating its target genes.[OsIDD2] (Mus musculus) PubMed

 21527.

VT1, a novel amidase effector in ETEC, significantly hydrolyzed D-lactyl-L-Ala crosslinks between N-acetylmuramoyl and L-Ala in peptidoglycan. The VT1/VTI1 effector/immunity pair is encoded within a typical vgrG island, and plays a critical role for the successful establishment of ETEC in host gut. (Mus musculus) PubMed

 21528.

loss of OsFLN1, HSA1/OsFLN2, or OsTRXz function perturbs the stability of the transcriptionally active chromosome complex and plastid-encoded RNA polymerase activity.[OsFLN1, TRXz] (Mus musculus) PubMed

 21529.

Secretion of EbfG1-4 is important for the formation of biofilms.[EbfG1-4] (Mus musculus) PubMed

 21530.

OsCPK24 functions as a positive regulator of cold stress tolerance in rice.[OsCPK24] (Mus musculus) PubMed

 21531.

TSC1 is indispensable for plastid development in the absence of light, and contributes to adaptation to transplantation shock.[TSC1] (Mus musculus) PubMed

 21532.

The authors have identified a gene (PpSAP1) of Prunus persica coding for a stress-associated protein (SAP) containing Zn-finger domains A20 and AN1. PpSAP1 was highly expressed in leaves and dormant buds, being down-regulated before bud dormancy release.[PpSAP1] (Mus musculus) PubMed

 21533.

productive reoviral infection is strongly correlated with elevated importin-beta and exportin-5 levels which may serve as biomarkers of the disease in clinical specimens[Importin-beta] (Mus musculus) PubMed

 21534.

Differences in sensitivity of prion fragmentation to Sis1 and in relative inputs of fragmentation and malpartition in prion propagation result in opposite effects of Sis1 relocalization on [PSI (+)] and [URE3]. (Mus musculus) PubMed

 21535.

Regulatory regions of genes CgYPS1 and CgYPS7 were polymorphic, harboring different transcription factor binding sites arrays, and showing differential expression profiles (CgYPS1 and CgYPS7). (Mus musculus) PubMed

 21536.

The agr group II may be associated with enterotoxin C production by S. epidermidis, increasing the virulence of strains isolated from blood cultures and consequently the severity of sepsis caused by these organisms. (Mus musculus) PubMed

 21537.

In this study, systematic gene disruption experiments were performed to study the functional roles of members of the Plasmodium yoelii ApiAP2 (PyApiAP2) gene family in parasite development. This study provides expression and functional information for many PyApiAP2 genes, which can be explored for disease management.[ApiAP2] (Mus musculus) PubMed

 21538.

Tetrahymena dynamin-related protein 6 (Drp6) self-assembles independent of membrane association.[Drp6] (Mus musculus) PubMed

 21539.

Here the authors present data showing that GroEL2, a substrate of Hip1, modulates dendritic cell functions. The full-length GroEL2 protein elicited robust proinflammatory responses from dendritic cells and promoted their maturation and antigen presentation to T cells. In contrast, the cleaved form of GroEL2, which predominates in Mycobacterium tuberculosis, was poorly immunostimulatory.[Hip1] (Mus musculus) PubMed

 21540.

These results suggest that M. smegmatis has two types of catalase-peroxidases, expressions of which are controlled under different gene regulatory systems. Isoniazid (INH) susceptibilities of the katG-null strains were also examined and it was found that katGI is a major determinant of M. smegmatis susceptibility to INH. (Mus musculus) PubMed

 21541.

In this study, the authors found that further deletion of PMC1, a vacuolar calcium pump, in tfp1/ mutant led to more severe dysregulation of calcium homeostasis. Besides, the tfp1/pmc1/ mutant was more sensitive to H2O2 and had a higher reactive oxygen species level.[PMC1] (Mus musculus) PubMed

 21542.

The Lr77 gene is new gene for adult plant leaf rust resistance in wheat mapping to chromosome 3BL [Lr77] (Mus musculus) PubMed

 21543.

silencing of Glu-1Ay in tetraploid and hexaploid wheat was attributed to the new premature stop codon and WIS 2-1A insertion in wild tetraploid wheat, and most silenced alleles were delivered to the cultivated tetraploid and hexaploid wheat, providing a clear evolutionary history of the Glu-1Ay gene in the wheat polyploidization and domestication processes [Glu-1Ay] (Mus musculus) PubMed

 21544.

Ppk1 catalyzed the transfer of a phosphate group between ADP molecules yielding ATP and AMP, thus exhibiting adenylate kinase activity.[Ppk1] (Mus musculus) PubMed

 21545.

STAYGREEN (CsSGR) is an anthracnose resistance gene [SGR] (Mus musculus) PubMed

 21546.

IPK2 role in the lateral root formation. IPK2 interacts with IAA11[IPK2] (Mus musculus) PubMed

 21547.

Study characterizes the Tpt1 enzyme from Runella slithyformis as a bona fide NAD+-dependent RNA 2'-phosphotransferase. Its biological activity relies on a conserved histidine and three conserved arginine that were shown to be essential for the in vivo activity of S. cerevisiae Tpt1 and E. coli KptA. [Tpt1] (Mus musculus) PubMed

 21548.

MIEL1 negatively regulates anthocyanin biosynthesis by ubiquitinating and degrading MdMYB1 protein.[MIEL1] (Mus musculus) PubMed

 21549.

Characterisation and mapping of the stripe rust resistance gene Yr80 [Yr80] (Mus musculus) PubMed

 21550.

the mutant hull splitting phenotype was controlled by a single recessive gene, sph (Os04g0447100), which encodes a type-2 13-lipoxygenase [SPH] (Mus musculus) PubMed

 21551.

rust resistance was found to be conferred by a single dominant gene (R 15 ) originating from HA-R8. [R 15] (Mus musculus) PubMed

 21552.

Ncgl1823 encode methionine sulphoxide reductase B of Corynebacterium glutamicum. The enzyme plays a limited role in resisting oxidative stress and it could reduce MetO to Met by the Trx/TrxR reducing system. (Mus musculus) PubMed

 21553.

The block 2 of msp-1 gene was found to be highly polymorphic, and overall allelic distribution showed that RO33 was the dominant allele (63%), followed by MAD20 (29%) and K1 (8%) alleles. However, an extensive diversity (9 alleles and 4 genotypes) and 6-10 repeat regions exclusively of R2 type were observed in glurp (Mus musculus) PubMed

 21554.

Rubrivivax gelatinosus mutant IL144 with the deletion of hup gene, which encoded a uptake hydrogenase, produced higher amounts of molecular hydrogen than the wild-type cells under nitrogen-deficient conditions under light. (Mus musculus) PubMed

 21555.

induced by auxin and promotes both plant growth and lateral root development by enhancing cell expansion - [GH9A7] (Mus musculus) PubMed

 21556.

The authors present new evidence on the function of PvTOC1 as a repressor of the promoter activity of its own gene, mediated by its conserved CCT (CONSTANS, CO-LIKE and TOC1) domain. Using their protoplast system they were able to uncover functions of the bean circadian clock and to identify an additional target of the PvTOC1clock transcription factor, not previously reported.[TOC1] (Mus musculus) PubMed

 21557.

These findings suggest that, when produced, NanI may be a significant contributor to C. perfringens human GI infections by promoting the intestinal growth and survival of this bacterium.[NanI] (Mus musculus) PubMed

 21558.

involved in the translocation of cadmium from roots to shoots - [FWL4] (Mus musculus) PubMed

 21559.

This study selectively incorporated p-cyanophenylalanine (CNF) as a vibrational probe at five distinct locations in the enzyme cytochrome P450cam and used IR spectroscopy to characterize the environments in substrate and/or ligand complexes reflecting those in the catalytic cycle. [P450cam] (Mus musculus) PubMed

 21560.

The findings suggest that lncRNA TCONS_00019174 exerts antidepressant-like effect in mice by activating Wnt/beta-catenin pathway (TCONS_00019174). (Mus musculus) PubMed

 21561.

Haplotype analysis identified specific SNPs linked to the stripe rust resistance gene Yr26 [Yr26] (Mus musculus) PubMed

 21562.

A point mutation in Rht23 resulted in pleiotropic effects on spike compactness and plant dwarfness. [Rht23] (Mus musculus) PubMed

 21563.

the Ryadg gene confers extreme resistance to potato virus Y [Ryadg] (Mus musculus) PubMed

 21564.

Capana02g002096 encodes a homolog of AtDYT1, which is a bHLH transcription factor and involves in the early tapetal development. Repression of Capana02g002096 led to a male-sterile phenotype. [Capana02g002096] (Mus musculus) PubMed

 21565.

A possible role of YB-1 in growth and development and stress response (YB-1). (Mus musculus) PubMed

 21566.

The DENV1 NS5 gene was sequenced to establish whether during an epidemic burst there were genetic variations of the virus and whether any variant was associated (through a casecontrol design) with severe clinical behavior. The variants 124Met/166Ser (amino acid positions according to the report GenBank AJL35015.1), were associated with a severe clinical course of the disease. [NS5] (Mus musculus) PubMed

 21567.

Serine 51 residue of Citrobacter freundii tyrosine phenol-lyase assists in C-alpha-proton abstraction and transfer in the reaction with substrate [tyrosine phenol-lyase] (Mus musculus) PubMed

 21568.

overexpression generates resistance against Bemisia tabaci infestation - [ghr-miR166b] (Mus musculus) PubMed

 21569.

HP0728 and HP1472 are virulence factors of E. rhusiopathiae. [HP0728 and HP1472 ] (Mus musculus) PubMed

 21570.

The secondary metabolites was regulated by LaeA in Aspergillus niger FGSC A1279. [LaeA] (Mus musculus) PubMed

 21571.

The structure-function relationship of MTP8.1 in Mn transport activity.The N-terminus of MTP8.1 was not functional for Mn transport activity. [MTP8.1] (Mus musculus) PubMed

 21572.

structures of the high pH resting state of homotrimeric chicken (Gallus gallus) ASIC1a, determined by X-ray crystallography and single particle cryo-electron microscopy, and a comprehensive molecular mechanism for proton-dependent gating in ASICs (Mus musculus) PubMed

 21573.

Calredoxin (CRX) represents a novel type of calcium-dependent sensor-responder connected to redox regulation in the chloroplast. [Calredoxin] (Mus musculus) PubMed

 21574.

There was no association between biofilm and genetic polymorphisms of scrA from S. mutans with severe early childhood caries in 3 years old children (scrA) (Mus musculus) PubMed

 21575.

The research described here specifies where in the JAK/STAT signaling cascade the IFN response is inhibited and which protein domain of [nonstructural protein 2 (nsP2) is responsible for IFN inhibition. The results illuminate new aspects of antiviral defense and CHIKV counterdefense strategies and will direct the search for novel antiviral compounds [nonstructural protein 2]. (Mus musculus) PubMed

 21576.

Study provides evidence for genetic fitness in Bacillus subtilis by the L20-interacting RNA cis-regulator of ribosomal protein synthesis. [L20] (Mus musculus) PubMed

 21577.

MoYpt7 interacts with MoGdi1 in Magnaporthe oryzae.The dominant negative isoform of MoYpt7 is essential for colony morphology, conidiation, and pathogenicity. [Ypt7, Gdi1] (Mus musculus) PubMed

 21578.

YAP promotes myelin and non-myelin genes transcription while the polarity protein Crb3, localized at the tips of the myelin sheath, activates the Hippo pathway to temper YAP activity, therefore allowing for optimal myelin growth.[Hippo] (Mus musculus) PubMed

 21579.

These results indicate that protein-disulfide bond formation catalyzed by OsPDIL1;1 is modulated by osa-miR5144-3p in rice during development and is involved in resistance to abiotic stress.[OsPDIL1;1, miR5144-3] (Mus musculus) PubMed

 21580.

overexpression confers disease resistance to Xanthomonas axonopodis pv. manihotis - [RXam1] (Mus musculus) PubMed

 21581.

acts as a negative regulator for saltstress response through the regulation of OCPI2 - [OsMAR1] (Mus musculus) PubMed

 21582.

all of the rice WOX3 genes are involved in leaf lateral outgrowth, but the functions of LSY1 and NAL2/3 have diverged.[WOX3, LSY1, NAL2, NAL3] (Mus musculus) PubMed

 21583.

insulin-activated SREBP1c downregulates gluconeogenesis through CRY1-mediated FOXO1 degradation.[SREBP1c] (Mus musculus) PubMed

 21584.

miR-19 suppresses the expression of Pten and plays a key role in regulating B-cell tolerance. (Mus musculus) PubMed

 21585.

Therefore, LmrR represents a dynamic type of transcriptional regulation of prokaryotic multidrug resistance systems, where the small affinity reduction induced by compounds is coupled to the functional relocalization of the repressor on the genomic DNA via nonspecific DNA adsorption.[LmrR] (Mus musculus) PubMed

 21586.

biophysical parameters like pocket (cavity) geometries and stabilizing residues of HCV 1a NS3/4A protease in wild type and mutants, were studies.[NS3, NS4A] (Mus musculus) PubMed

 21587.

the i-region genotype of vacA is a useful marker of both H. pylori virulence and the clinical outcomes of H. pylori infections in Okinawa, Japan (vacA) (Mus musculus) PubMed

 21588.

To optimize the expression of type A ferulic acid esterase (FaeA) from Aspergillus niger in Pichia pastoris X-33 using codon optimization.. Recombinant FaeA was capable to prevent the oxidative gelation of PAX formation by breaking the cross-linking of FA among AX chains and improve the filtration performance of wort (Mus musculus) PubMed

 21589.

The P. olivaceus P2Y2 and P2Y12 receptors harbor seven transmembrane domains but share only 24% sequence identity. Real-time PCR analysis revealed the constitutive but unequal mRNA expression pattern of P2Y2R and P2Y12R in normal Japanese flounder tissues with the dominant expression of P2Y2R in head kidney and blood and P2Y12R in hepatopancreas.[P2Y12] (Mus musculus) PubMed

 21590.

Study shows the molecular cloning of oligopeptidase A (OpdA) and its expression in E. coli. The purified OpdA showed more than 80% inhibition with a serine protease inhibitor but the activity was reduced to 30% with the cysteine protease inhibitor. The peptidase activity was increased significantly in the presence of Zn(2+) at a neutral pH. Also, results show the presence of more than one active sites. [OpdA] (Mus musculus) PubMed

 21591.

The presence of unique DNA-independent ATPase and DNA unwinding activities of OsRuvBL1a protein and upregulation of its transcript under abiotic stress conditions suggest its involvement in multiple cellular pathways.[OsRuvBL1a] (Mus musculus) PubMed

 21592.

plexins function in epithelial wound healing in diverse taxa.[PlexA] (Mus musculus) PubMed

 21593.

A unique innate immune evasion strategy of B. burgdorferi is orchestrated by the BBA57 surface protein through its modulation of multiple spirochete virulent determinants. Its function is critical for early infection but not for later stages of spirochetal persistence, either in mammals or ticks. The protein influences host IFN responses as well as suppresses multiple host microbicidal activities. BBA57. (Mus musculus) PubMed

 21594.

The replicase (DNA polymerase III holoenzyme) contains 2 copies of the same polymerase (the dnaE gene product). Although the two DNA strands are copied by the same polymerase, they are not copied with the same accuracy. This effect results from the greater dissociative character of the lagging-strand dnaE polymerase, which provides additional options for error removal. (Mus musculus) PubMed

 21595.

RNase E cluster positions correlated with the subcellular location of chromosomal loci of two highly transcribed rRNA genes, suggesting that RNase E's function in rRNA processing occurs at the site of rRNA synthesis. (Mus musculus) PubMed

 21596.

The authors demonstrated that the protein encoded by DNA-N (NSP) is mandatory for aphid transmission. They showed that NSP acts as a nanovirus transmission factor, the existence of which had been hypothesized earlier.{NSP] (Mus musculus) PubMed

 21597.

These results suggest that the nuclear localization of viral protein 22K appear essential for virus replication and production of progeny bovine adenovirus-3.[22K] (Mus musculus) PubMed

 21598.

acts as a positive regulator of transketolase in response to salinity and osmotic stress - [OsSIRP2] (Mus musculus) PubMed

 21599.

The lobed-leaf gene was mapped to a region from 15.701 to 15.817M on A10. In light of annotations of the genes in candidate region, a leaf morphological development related gene, Bra009510, was primary identified as the candidate gene. The full length of the candidate gene was 1390bp containing three exons and two introns in the two parents.[Bra009510] (Mus musculus) PubMed

 21600.

loss of chromatin resetting factor Set2 or the subsequent production of Set2-repressed antisense transcripts does not affect the abundance of the sense transcripts.[Set2] (Mus musculus) PubMed

 21601.

the distance between an mRNA and overlapping long noncoding RNA promoter determines whether Set2-Rpd3S or Set3C represses.[Set2, Rpd3S] (Mus musculus) PubMed

 21602.

we successfully expressed the putative Cry1Ac toxin-binding region (CR7-CR11) of Plutella xylostella cadherin-like in Escherichia coli BL21 (DE3). The expressed CR7-CR11 fragment showed binding ability to Cry1Ac toxin under denaturing (Ligand blot) and non-denaturing (ELISA) conditions. (Mus musculus) PubMed

 21603.

The authors identify and confirm interaction of M72 with the eukaryotic chaperonin tailless complex protein -1 (TCP-1) ring complex (TRiC) or chaperonin containing tailless complex polypeptide 1 (CCT). Accumulating biochemical evidence indicates M72 forms homo-oligomers and is a substrate of TRiC/CCT (Mus musculus) PubMed

 21604.

GaGSTF9 was a key regulator mediating cotton responses to V. dahliae and a potential candidate gene for cotton genetic improvement.[GaGTF9] (Mus musculus) PubMed

 21605.

Mdm10 promotes the biogenesis of alpha-helical and beta-barrel proteins at sorting and assembly machinery.[Mdm10] (Mus musculus) PubMed

 21606.

To understand how selection acts on protein networks, the yeast mating receptor Ste2, a pheromone-activated G protein-coupled receptor, was used as a model system.[Ste2] (Mus musculus) PubMed

 21607.

This work presents long distance measurements up to 160 A in the GroEL tetradecamer using electron-electron resonance (DEER) Electron Spin Resonance Spectroscopy. [GroEL] (Mus musculus) PubMed

 21608.

CWP1 ablation allows functional characterization of a conditional phenotype in parasites induced to encyst.[CWP1] (Mus musculus) PubMed

 21609.

Tissue expression patterns appeared different between the SR-As; however the only statistically significant difference in expression was seen in the muscle, where SCARA3, SCARA4, and SCARA5 all showed high expression. [SCARA3, SCARA4] (Mus musculus) PubMed

 21610.

The results demonstrate that GhVLN4 is involved in the generation of actin filament bundles, suggesting that GhVLN4 may play important roles in regulating plant cell morphogenesis and expansion by remodeling actin cytoskeleton. [GhVLN4] (Mus musculus) PubMed

 21611.

ETF beta subunit encoding gene and ETFDH play an important role in fungal development and plant infection in M. oryzae by regulation of fatty acid metabolism, turgor establishment and induction of host ROS accumulation. [ETF beta subunit; ETFDH] (Mus musculus) PubMed

 21612.

the sequence and structure of CYP51 in a laboratory strain (MRHO/IR/75/ER) of L. major were determined and compared to the wild-type strain.[CYP51] (Mus musculus) PubMed

 21613.

These data highlight a novel role for agnoprotein and begin to reveal the mechanism by which polyomaviruses leave an infected cell.[Agnoprotein] (Mus musculus) PubMed

 21614.

RepID-depleted murine embryonic fibroblasts exhibit abnormal replication fork progression and fewer replication-initiation events.[RepID] (Mus musculus) PubMed

 21615.

Nop9 is critical for timely cleavage of the 20S pre-rRNA. [Nop9] (Mus musculus) PubMed

 21616.

These findings establish lineage switch as a mechanism of CAR resistance exposing inherent plasticity in genetic subtypes of pre-B-cell ALL.[CD19 CAR] (Mus musculus) PubMed

 21617.

a metal-responsive DNA condensation mechanism controlled by the Helicobacter pylori ferric uptake regulator (Fur), is reported.[Fur] (Mus musculus) PubMed

 21618.

Overexpression of CYP6BG1 may contribute to chlorantraniliprole resistance in P. xylostella. [CYP6BG1] (Mus musculus) PubMed

 21619.

Infectious salmon anaemia virus s8ORF2 was identified as a novel interactor with Salmo salar SsMov10, a key molecule responsible for RISC assembly and maturation in the RNAi pathway.[s8ORF2] (Mus musculus) PubMed

 21620.

Cell Counting Kit-8 results showed that ectopically expressed human cytomegalovirus miR-UL112 can significantly increase the proliferation of HUVECs. (Mus musculus) PubMed

 21621.

these results indicate that the three BdFAR genes encode active fatty acyl-CoA reductase involved in the biosynthesis of Brachypodium wax primary alcohols and respond to abiotic stresses.[BdFAR] (Mus musculus) PubMed

 21622.

The authors identified a gene encoding for a putative Factor H-binding protein, termed CbiA (complement binding and inhibitory protein A). Functional analyses revealed that CbiA interacted with complement regulator Factor H (FH), C3, C3b, C4b, C5, and C9. (Mus musculus) PubMed

 21623.

a complete catalytic cycle for both proton and sodium-pumping M-PPases, and one that also explains the basis for ion specificity, is reported.[M-PPase] (Mus musculus) PubMed

 21624.

a complete catalytic cycle for both proton and sodium-pumping M-PPases, and one that also explains the basis for ion specificity, is reported.[M-PPase] (Mus musculus) PubMed

 21625.

Taken together, these results suggest that MoERR1 is a endoplasmic reticulum retention receptor required for function and integrity of endoplasmic reticulum, and that MoERR1-mediated endoplasmic reticulum functionalities are essential for fungal development and pathogenesis.[MoERR1] (Mus musculus) PubMed

 21626.

Findings provided evidence, that the treatment of L. donovani with TNP-470, a MAP2 inhibitor prevented the induction of apoptosis in miltefosine induced promastigotes, but was not able to prevent cell death of the parasites. These results suggest the role of MAP2 in L. donovani, as an effector molecule in higher eukaryotes which is important for the induction of apoptosis but unable to prevent cell death. [MAP2] (Mus musculus) PubMed

 21627.

genetic deletion of endothelial VEGFR2, knockout of the Pdgf-c gene or pharmacological blockade of PDGFR-alpha impair the WAT-beige transition.[Pdfg c] (Mus musculus) PubMed

 21628.

The dependence of ATP-dependent transport on proton coupling, and the stimulation of MsbA-ATPase by the chemical proton gradient highlight the functional integration of both forms of metabolic energy.[MsbA] (Mus musculus) PubMed

 21629.

A Tyr137 amino acid mutation in the cytochrome P450 FgCYP51B could lead to resistance to tebuconazole and that residue Y137 forms part of the tebuconazole-binding pocket.[CYP51B] (Mus musculus) PubMed

 21630.

these findings demonstrate that ZmSLAC1 is involved in stomatal closure mainly by mediating the efflux of nitrate in maize.[ZmSLAC1] (Mus musculus) PubMed

 21631.

These results suggest a molecular basis for regulation of the balance between florigen FT and anti-florigen TFL1.TFL1, 14-3-3, FD][ (Mus musculus) PubMed

 21632.

Molecular basis for the integration of environmental signals by FurB from Anabaena sp. PCC 7120. has been uncovered. [FurB] (Mus musculus) PubMed

 21633.

digestion of thrombin by P. aeruginosa elastase leads to the release of the C-terminal thrombin-derived peptide FYT21, which inhibits pro-inflammatory responses to several pathogen-associated molecular patterns.[Pseudolysin] (Mus musculus) PubMed

 21634.

Quantitative expression analyses confirmed the hypothesis of functional redundancy of PvMRP1 and PvMRP2 in almost all plant organs with the exception of developing cotyledons, where only PvMRP1 is expressed at appreciable levels. [PvMRP1; PvMRP2] (Mus musculus) PubMed

 21635.

GhWUS is an important regulator of somatic embryogenesis and shoot regeneration. [GhWUS1a; GhWUS1b] (Mus musculus) PubMed

 21636.

suggest that K2P1.1 participates in neuropathic pain development and maintenance and may be a potential target in the management of this disorder[K2p1.1] (Mus musculus) PubMed

 21637.

Once an RNA-DNA heteroduplex of 8 bp or more is formed, Cas9-RNA establishes a stable complex with the DNA, regardless of protospacer-adjacent motif-distal mismatches. [Cas9] (Mus musculus) PubMed

 21638.

the multilayered ribosomal interaction allows positioning of Ssb in an optimal orientation to the tunnel exit guaranteeing an efficient nascent polypeptide interaction.[Ssb1] (Mus musculus) PubMed

 21639.

cGAMP activates CapV phospholipase activity to target the cell membrane and suggest that acquisition of this second messenger signaling pathway may contribute to the emergence of the El Tor biotype as the etiological agent behind the seventh cholera pandemic. (Mus musculus) PubMed

 21640.

Site-directed mutagenesis of conserved residues revealed that Na(+)- and H(+)-driven conformational changes are facilitated by a network of polar residues in the N-terminal domain cavity, whereas conserved carboxylates buried in the C-terminal domain are critical for stabilizing the drug-bound state. Interpreted in conjunction with doxorubicin binding of mutant NorM-Vc and cell toxicity assays (Mus musculus) PubMed

 21641.

study provides insights into the structural basis for the complex ion dependency of MATE transporters. (Mus musculus) PubMed

 21642.

These findings suggest that Ni insertion into the active site induces spatial rearrangement of both the N- and C-terminal tails of HyhL, which function as a key checkpoint for the completion of the Ni-Fe cluster assembly. (Mus musculus) PubMed

 21643.

Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease (Mus musculus) PubMed

 21644.

ATP hydrolysis by UPF1 modulates a functional interaction between the Nonsense-mediated mRNA decay machinery and terminating ribosomes necessary for targeting substrates to accelerated degradation.[UPF1] (Mus musculus) PubMed

 21645.

during the neurula stage, Nodal and Hh cooperate in gill slit development - Hh mediates gill slit formation and Nodal establishes their left-right position.[Nodal, Hedgehog] (Mus musculus) PubMed

 21646.

These results suggest that endoplasmic reticulum-targeted OsSAC1 may indirectly regulate sugar partitioning in carbon-demanding young leaves and developing leaf sheaths.[OsSAC1] (Mus musculus) PubMed

 21647.

The results characterize the first PhnP family member that is a diphosphatase rather than a cyclic phosphodiesterase and suggest its involvement in a cellular damage-control system that efficiently hydrolyzes the reactive, ADP-ribose-like products of FAD photodegradation. [PhnP] (Mus musculus) PubMed

 21648.

Functional characterization of the Ca(2+)-ATPase SMA1 from Schistosoma mansoni has been reported. [SMA1] (Mus musculus) PubMed

 21649.

Findings are indicative of VcaM being capable of a one-step substrate translocation from cytosol to extracellular space utilising the TolC-channel, making it the only multidrug ABC-transporter outside of the MacB-family with demonstrable TolC-dependency. [VcaM] (Mus musculus) PubMed

 21650.

bmo-miR-390 significantly downregulates the expression of BmNPV-cg30. [Mir-390] (Mus musculus) PubMed

 21651.

A novel Bombyx mori host protein SINAL10 interacting with nucleopolyhedrovirus GP64 protein and its role in Bombyx mori nucleopolyhedrovirus infection have been reported. [SINAL10] (Mus musculus) PubMed

 21652.

Chicken RPL18 in association with VP3 and PKR affect viral replication. [RPL18] (Mus musculus) PubMed

 21653.

the expression product of the uncharacterized pa4088 gene from the opportunistic pathogen Pseudomonas aeruginosa PAO1, is reported.[GSAM] (Mus musculus) PubMed

 21654.

the first report to verify the DNA binding activity of the CAV capsid protein, VP1 (VP1) (Mus musculus) PubMed

 21655.

Our findings indicate that CcTLR21 plays a significant role in innate immune defense during larvae ontogeny and in responses to viral or bacterial pathogens (Mus musculus) PubMed

 21656.

In HIV-1-producing cells, gp41 exists in a complexed form with caveolin-1, an interaction most probably mediated by the caveolin-1 binding motif. This sequence is highly conserved in every single HIV-1 isolate, thus suggesting that there is constant selective pressure to preserve this sequence for a specific function in the HIV infectious cycle [Gp41]. (Mus musculus) PubMed

 21657.

Here, we confirm an interaction between p300 and the adenovirus 2 large E1A activation domain (AD) and map the interacting regions in E1A by observing colocalization at an integrated lacO array of fusions of LacI-mCherry to E1A fragments with YFP-p300 [E1A]. (Mus musculus) PubMed

 21658.

trans-Golgi-localized transporter that is involved in Mn tolerance and required for normal fertility - [MTP11] (Mus musculus) PubMed

 21659.

The findings suggest that sequence diversity in Pfhrp2 and Pfhrp3 genes in Indian isolates is not likely to negatively influence performance of currently used PfHRP2 rapid diagnostic tests . (Mus musculus) PubMed

 21660.

A novel porcine 2',5'-oligoadenylate synthetase-like protein (OASL2) exhibiting antiviral activity has been identified. [OASL2] (Mus musculus) PubMed

 21661.

With four putative DAH7PS enzymes, P. aeruginosa appears to have evolved control of shikimate pathway flux at the genetic level, rather than control by multiple allosteric effectors to a single type II DAH7PS, as in M. tuberculosis. Type II DAH7PSs, thus, appear to have a more varied evolutionary trajectory than previously indicated. (Mus musculus) PubMed

 21662.

downregulation of gene expression confers a truncated light-harvesting antenna (TLA) and enhances biomass and leaf-to-stem ratio - [SRP43] (Mus musculus) PubMed

 21663.

the equilibrium of this mutant is shifted toward the semi-open state in its resting state and interacts with MBP with high affinity, providing an explanation for the inhibition of MalG511 by MBP at higher concentrations. In contrast, the mutant binding protein, MBPG13D, interacts with lower affinity and could restore MalG511 to a normal catalytic cycle (Mus musculus) PubMed

 21664.

This study examined the enzymatic characteristics of SpOatAC-catalyzed reactions through analysis of both pre-steady- and steady-state kinetics. Our findings clearly show that SpOatAC follows a ping-pong bi-bi mechanism of action involving a covalent acetyl-enzyme intermediate (Mus musculus) PubMed

 21665.

The attachment of WSSV might be mediated by the interaction between VP37 and a heparin-like molecule presented on shrimp cells. [VP37] (Mus musculus) PubMed

 21666.

enhances tolerance to multiple abiotic stresses through the ABA signaling pathway in transgenic tobaccos by altering physiological and biochemical processes - [GF14b] (Mus musculus) PubMed

 21667.

the onset of de novo deoxycorticosterone synthesis in parallel with endogenous corticosteroid receptor mRNA production from fertilization to the swim-up stage in rainbow trout.[corticosteroid receptor] (Mus musculus) PubMed

 21668.

Ctrp9, adiponectin receptor 1 (Adipor1) and Adipor2 were identified from Nile tilapia.[Ctrp9, Adipor1, Adipor2] (Mus musculus) PubMed

 21669.

For Fdc1 the FMN cofactor binding confers structural stability to the enzyme.[Fdc1] (Mus musculus) PubMed

 21670.

the MAPK pathway is activated for FKS1 mutant survival and the synthesis of cell wall components are reinforced in the FKS1 mutant.[FKS1] (Mus musculus) PubMed

 21671.

Protective epitopes were located in the N and C termini of the OppA. [OppA] (Mus musculus) PubMed

 21672.

As the maturation of dendritic cells plays a central role in initiating inflammation and activating the adaptive immune response, the present findings shed new light on the immunostimulatory properties of CNF1 and may explain why the toxin functions as an immunoadjuvant. (Mus musculus) PubMed

 21673.

show that ClfA behaves as a force-sensitive molecular switch that potentiates staphylococcal adhesion under mechanical stress[Clumping factor A] (Mus musculus) PubMed

 21674.

The C terminus of ApiA forms an independent domain that is crucial for general stability and trimer formation, which appears to be associated with autoaggregation, biofilm formation, and surface expression.[ApiA] (Mus musculus) PubMed

 21675.

Cas9-mediated repression of regR transcription is important for S. agalactiae to open the blood-brain barrier and thereby cause meningitis.[Cas9, regR] (Mus musculus) PubMed

 21676.

By leptospiral outer membrane protein extraction and fractionation, the authors identified the proteins LipL21 and LipL45 as myeloperoxidase inhibitors, constituting new Leptospira virulence factors.[LipL21] (Mus musculus) PubMed

 21677.

Leu25 facilitates the inward-to-outward transition by compensating a Na(+)- and substrate-free state and acts as the gatekeeper for Na(+) binding that prevents leak in inward-outward return transitions. [LeuT] (Mus musculus) PubMed

 21678.

UvrA dissociates from the lesion complex, allowing UvrB to orchestrate the downstream nucleotide excision repair reactions. [UvrA ] [UvrB] (Mus musculus) PubMed

 21679.

This study demonstrates that Tpk1 is involved in drug tolerance and cell wall integrity, while Tpk2 serves as a key regulator in dimorphism and adhesion. Both Tpk1 and Tpk2 are required for growth and full virulence in Candida tropicalis.[Tpk1, Tpk2] (Mus musculus) PubMed

 21680.

Prevalence of a new variant OXA-204 and OXA-48 carbapenemases plasmids encoded in Klebsiella pneumoniae clinical isolates in Tunisia has been reported. [OXA-204] (Mus musculus) PubMed

 21681.

ORF2 protein has 144 conserved sites.Structural conservation of the S and M ORF2 domains. (Mus musculus) PubMed

 21682.

Puf118 binds chemotaxis-related mRNAs at the cell front. [puf118] (Mus musculus) PubMed

 21683.

Cryo-electron microscopy determined a DNA cleavage-activating architecture of Cas9. [Cas9] (Mus musculus) PubMed

 21684.

[lPDC5] KmPDC5 deletion did not generate any apparent change in Pyruvate decarboxylase activity or growth patterns under several tested conditions (Mus musculus) PubMed

 21685.

Thus, a plasma membrane-resident protein complex consisting of SPL11 cell-death suppressor 2 (SDS2), SPL11, and OsRLCK118/176 controls programmed cell death and immunity in rice.[SDS2] (Mus musculus) PubMed

 21686.

Thus, Listeria monocytogenes uses Listeria adhesion protein (LAP) to exploit epithelial defenses and cross the intestinal epithelial barrier.[LAP] (Mus musculus) PubMed

 21687.

Data presented in this work indicated that the A1S_0242 (feoA) gene from Acinetobacter baumannii ATCC 17978 strain plays a role in fitness, adhesion, biofilm formation, growth, and, definitively, in virulence.[feoA] (Mus musculus) PubMed

 21688.

SeV V protein inhibited the assembly of NLRP3 inflammasomes, including NLRP3-dependent ASC oligomerization, NLRP3-ASC association, NLRP3 self-oligomerization, and intermolecular interactions between NLRP3 molecules. (Mus musculus) PubMed

 21689.

Genome-wide fitness assessment during diurnal growth reveals an expanded role of the cyanobacterial circadian clock protein KaiA. (Mus musculus) PubMed

 21690.

Here, the authors report that pseudorabies virus down-regulated swine leukocyte antigen class I (SLA-I) molecules on the surface of PK-15 cells and targeted them for degradation through lysosome pathway. Viral pUL56 protein was associated with this function by inducing degradation of cellular SLA-I heavy chain (HC) in a manner that was dependent on the lysosome machinery.[pUL56] (Mus musculus) PubMed

 21691.

an apple repressor MdMYB15L might play a key role in the cold signaling and anthocyanin metabolic pathways.[MdMYB15L] (Mus musculus) PubMed

 21692.

Plasmid-mediated colistin resistance gene mcr-1 in an Escherichia coli ST10 bloodstream isolate in the Sultanate of Oman has been reported. [mcr-1] (Mus musculus) PubMed

 21693.

Microbiological characteristics of qacA/qacB-positive methicillin-resistant Staphylococcus aureus isolates in a surgical intensive care unit in the Republic of Korea have been reported. [qacA] (Mus musculus) PubMed

 21694.

New Delhi metallo-beta-lactamase variants NDM-4, NDM-5, and NDM-7 in Enterobacter aerogenes isolated from a neonatal intensive care unit of a North India hospital have been reported. [NDM-4],[NDM-5],[NDM-7] (Mus musculus) PubMed

 21695.

XopL is essential for in planta growth and full virulence.[XopL] (Mus musculus) PubMed

 21696.

The presented data suggest that TaMDC1 is involved in a broad spectrum biotic stress resistance in planta. [TaMDC1] (Mus musculus) PubMed

 21697.

EcZinT structure shows the fewest zinc ions bound of all reported EcZinT structures.[EcZinT] (Mus musculus) PubMed

 21698.

OsGASR3 (LOC_Os03g55290)) inhibited the hyphal growth of Fusarium oxysporum f.sp. cubense and Helminthosporium oryzae at a relatively low concentration. Furthermore, OsGASR3 exhibited in planta inhibitory activity against Xanthomonas campestris, suggesting its involvement in defense mechanisms, in addition to its previously reported functions affecting growth and development (OsGASR3). (Mus musculus) PubMed

 21699.

ClpB can support the virulence of L.interrogans by protecting the conformational integrity and catalytic activity of multiple metabolic enzymes, thus maintaining energy homeostasis in pathogen cells.[ClpB] (Mus musculus) PubMed

 21700.

an Osfuct mutant that displayed pleiotropic developmental defects, such as impaired anther and pollen development, diminished growth, shorter plant height, fewer tillers, and shorter panicle length and internodes under field conditions, was characterized.[OsFuct] (Mus musculus) PubMed

 21701.

Bsr-k1 role in the disease resistance against Magnaporthe oryzae and Xanthomonas oryzae pv oryzae. [Bsr-k1] (Mus musculus) PubMed

 21702.

In conclusion, the ORF3 protein, especially its proline residues at aa 93 and 96, is essential for the release of membrane-associated rat hepatitis E virus particles, and ORF4 is unnecessary for the replication of rat hepatitis E virus.[ORF3, ORF4] (Mus musculus) PubMed

 21703.

These findings revealed that DeltaSEN1005 was attenuated in vitro as well as in vivo and the authors propose this hypothetical protein to play a role in altering the expression of genes involved in Salmonella virulence.[SEN1005] (Mus musculus) PubMed

 21704.

A role for noncoding RNA 7SK as an essential interactor of hnRNP R to regulate its function in axon maintenance.[noncoding RNA 7SK] (Mus musculus) PubMed

 21705.

The influence of sodium and sugars on SGLT conformation [SGLT] (Mus musculus) PubMed

 21706.

SRRP protein structure provides mechanistic insights into the role of SRRP in the host-microbe interactions [SRRP] (Mus musculus) PubMed

 21707.

PBP1b regulation by LpoP protein.Lpop primary structure.[PBP1b] [LpoP] (Mus musculus) PubMed

 21708.

Deletion of fptB significantly alters the intracellular life cycle of F. tularensis, attenuating intracellular replication in both cell line-derived and primary macrophages and inducing a novel cytosolic escape delay. [ fptB ] (Mus musculus) PubMed

 21709.

mutation in SarA affects its structure, function and stability [SarA] (Mus musculus) PubMed

 21710.

Together, Val1686 and Val1680 work together to induce apoptosis, cell rounding and cell lysis of Vibrio alginolyticus-infected fish cells.[ Val1686, Val1680] (Mus musculus) PubMed

 21711.

These results indicate that the Bm8 protein suppresses viral propagation to varying degrees in each larval tissue, which may establish Bombyx mori nucleopolyhedrovirus tissue tropisms in Bombyx mori larvae.[Bm8] (Mus musculus) PubMed

 21712.

OsBBS1/OsRLCK109 was expressed in all detected tissues and was predominantly expressed in the main vein region of mature leaves. The expression of OsBBS1 could be greatly induced by salt stress, and the bbs1 mutant exhibited hypersensitivity to salt stress. [OsBBS1 ] (Mus musculus) PubMed

 21713.

ADH (alcohol dehydrogenase) was found to be thermophilic with optimal activity at 65 degrees C. The enzyme displayed dual cofactor specificity and a broad substrate scope, and maximum activity was detected with benzyl alcohol and 2-phenyl-1-propanol. (Gene ADH). (Mus musculus) PubMed

 21714.

OsPKS2 is critical for pollen wall formation.[OsPKS2] (Mus musculus) PubMed

 21715.

silencing of MKK5 alters cell growth, energy metabolism, protein and fatty acids biosynthesis in procyclic T. brucei. (Mus musculus) PubMed

 21716.

RTD1 was preferentially expressed in green leafy tissues, and the protein was located in chloroplasts.[RTD1] (Mus musculus) PubMed

 21717.

UGT92G6 functions as a mono- and diglucosyltransferase in vitro.[UGT92G6] (Mus musculus) PubMed

 21718.

Rht25b is gibberellin-sensitive and shows significant pleiotropic effects on coleoptile length, heading date, spike length, spikelet number, spikelet density, and grain weight. Rht25 represents a new alternative dwarfing locus. [Rht25] (Mus musculus) PubMed

 21719.

We identified a 7-bp insertion that included a cis-element GATA box sequence at the promoter region of the Vrn-A3 locus. The early flowering trait of TN26 was caused by the GATA box in Vrn-A3. [Vrn-A3] (Mus musculus) PubMed

 21720.

mapping of a recessive powdery mildew resistance gene Pm61 from wheat landrace Xuxusanyuehuang [Pm61] (Mus musculus) PubMed

 21721.

Both the isoforms pf DLDH showed maximum activity in pH range of 7.0-8.0 and temperature 50+/-5 degrees C in the physiological direction.[DLDH] (Mus musculus) PubMed

 21722.

Here, the authors show that the Francisella tularensis subsp. holarctica gene locus FTS_0886 codes for functional HU protein which is essential for full Francisella virulence and its resistance to oxidative stress.[HU] (Mus musculus) PubMed

 21723.

Collectively, these data reveal that VraSR is a critical regulatory system that contributes to the survival of Streptococcus suis and its ability to defend against host innate immunity.[VraSR] (Mus musculus) PubMed

 21724.

A gene that encodes a protein dedicated to cell-to cell movement (P1) of Cauliflower mosaic virus is responsible for breaking resistance in Arabidopsis thaliana ecotype Enkheim (En-2). [P1] (Mus musculus) PubMed

 21725.

the accumulation of VpPR10.1 likely enhanced the transgenic plants resistance to downy mildew.[VpPR10.1] (Mus musculus) PubMed

 21726.

The role of rpoB mutations in the rifampicin resistance in Staphylococcus epidermidis.[rpoB] (Mus musculus) PubMed

 21727.

MYB30, MYB55 and MYB110 are involved in the signal pathway between microbe-associated molecular pattern perception and cinnamate/monolignol synthesis, and have important roles for plant immunity.[MYB55, MYB110] (Mus musculus) PubMed

 21728.

the roles of rfaD and rfaF genes in H. parasuis SC096 on lipooligosaccharide-induced pro-inflammatory factors and the related signaling pathways in porcine alveolar macrophages (rfaD and rfaF) (Mus musculus) PubMed

 21729.

Data suggest that expression of microRNA-128-3p is down-regulated during adipogenesis; an abundance of microRNA-128-3p appears to down-regulate adipogenesis and up-regulate lipolysis in adipocytes by targeting expression of Pparg (peroxisome proliferator-activated receptor gamma) and Sertad2 (SERTA domain-containing protein-2). [Mir128-3, microRNA-128-3] (Mus musculus) PubMed

 21730.

analysis of the holoenzyme organization for two-subunit pyruvate carboxylase [PC] (Mus musculus) PubMed

 21731.

GPR132 was significantly associated with hypoxia-tolerant traits in tllapia.[GPR32] (Mus musculus) PubMed

 21732.

CsATAF1 functioned as a positive regulator in response to drought stress by an abscissic acid-dependent pathway and decreasing reactive oxygen species (ROS) accumulation in cucumber.[CsTAF1] (Mus musculus) PubMed

 21733.

mutations in the Waxy gene reduce amylose content and convert the rice into glutinous ones without affecting other desirable agronomic traits, offering an effective and easy strategy to improve glutinosity in elite varieties. [Waxy] (Mus musculus) PubMed

 21734.

3 new DNA methyltransferases were identified. M.Ssp6803II, encoded by the sll0729 gene, modifies GGm4CC, M.Ssp6803III, encoded by slr1803, represents the cyanobacterial dam-like methyltransferase modifying Gm6ATC, and M.Ssp6803V, encoded by slr6095 on plasmid pSYSX, transfers methyl groups to the bipartite motif GGm6AN7TTGG/CCAm6AN7TCC. (genes: sll0729, slr1803, slr6095, slr6050) (Mus musculus) PubMed

 21735.

These results suggested that Nephotettix cincticeps tropomodulin was involved in viral spread by directly interacting with rice dwarf virus Pns10 tubules, finally promoting rice dwarf virus infection.[Pns10] (Mus musculus) PubMed

 21736.

data provide valuable information for better understanding the potential biological function of nsp1beta during PRRSV infection (nsp1b) (Mus musculus) PubMed

 21737.

TaNAC30 negatively regulates plant resistance in a compatible wheat-Pst interaction.[TaNAC30] (Mus musculus) PubMed

 21738.

the present work suggests that HSV-1 miRNA miR-H1 promotes the accumulation of neurodegeneration-associated proteins(miR-H1) (Mus musculus) PubMed

 21739.

NrrA facilitates cell survival by activating glycogen degradation and the oxidative pentose phosphate (OPP) pathway under nitrogen-deprived conditions. [NrrA] (Mus musculus) PubMed

 21740.

LML1 forms a functional complex with a eukaryotic elongation factor 1A (eEF1A)-like protein, SPL33/LMM5.1, whose mutant phenotype was similar to the lml1 phenotype.[LML1, SPL33] (Mus musculus) PubMed

 21741.

Atpc mutation in the optochin-resistant Streptococcus pneumoniae strains isolates from Tunisia.[Atpc] (Mus musculus) PubMed

 21742.

Results indicated that the VRN1 protein directly binds to the CArG-box in the promoter region of WFT, suggesting the direct up-regulation of WFT by VRN1 in the leaves of wheat plants. [VRN1] & [WFT] (Mus musculus) PubMed

 21743.

There appears to be a lower limit of pH capable of upregulating lipF promoter expression and this limit is not due to cell death.[lipF] (Mus musculus) PubMed

 21744.

In Cynoglossus semilaevis, rps6kb2 has a general role in tissue transformations during metamorphosis including tail changes, skull remodeling, eye migration, and asymmetrical pigmentation.[ rps6kb2] (Mus musculus) PubMed

 21745.

MgrB mutations and insertion sequence transpositions causing colistin resistance in a clinical strain of carbapenem-resistant Klebsiella pneumoniae from Vietnam.[MgrB] (Mus musculus) PubMed

 21746.

Data suggest that SPMS protein and mRNA are expressed in ovarian follicles; thus, SPMS may play important role in follicular development and ovulation. The open reading frame of SPMS cDNA is 1092 bp in length, encoding 363-amino-acid protein with molecular weight of 41 kDa. [SPMS, spermine synthase] (Mus musculus) PubMed

 21747.

Data suggest that mitochondrial functions in osteoblasts during osteogenesis are regulated, in part, by CypD-mPTP axis; CypD appears to contribute to mitochondrial dysfunction in bone inflammation via excessive opening of mPTP. (CypD = cyclophilin D; mPTP = mitochondrial permeability transition pore) [mPTP, mitochondrial permeability transition pore] (Mus musculus) PubMed

 21748.

adaptive gating of the bacterial mechanosensitive channel MscS [MscS] (Mus musculus) PubMed

 21749.

HTLV-1 protein gp46 is genetically stable in an endemic region of the Brazilian Amazon; a significant mutation (N93D) is present only in symptomatic patients. [gp46] (Mus musculus) PubMed

 21750.

the presence of nonheme iron (hemosiderin) and deposits of the "age pigment" lipofuscin in reproductively aged mouse ovaries, is reported.[Hemosiderin] (Mus musculus) PubMed

 21751.

MacP localizes to the division site of S. pneumoniae, forms a complex with PBP2a, and is required for the in vivo activity of the synthase. [MacP] (Mus musculus) PubMed

 21752.

Here, we discuss the implications of the dynamic patterns of early X-Delta-2 expression in the prospective somites (somitomeres) of Xenopus laevis. We report that right somitomeres normally emerge before left to form chiral structures (i.e. structures having clockwise or counter-clockwise handedness) (Mus musculus) PubMed

 21753.

mDia1can sense the force and torque during F-actin filament polymerization. (Mus musculus) PubMed

 21754.

Cas9 is active between 20 and 70 degrees C and tolerates fewer spacer-protospacer mismatches.[Cas9] (Mus musculus) PubMed

 21755.

Knockdown studies of the AeVago1 gene in Wolbachia-infected cells led to significant increases in dengue virus (DENV) replication, with no effect on Wolbachia density. These results suggest that the Wolbachia-induced AeVago1 in Ae. aegypti may function as a host factor to suppress DENV replication in the mosquito. (Mus musculus) PubMed

 21756.

The LeuT-fold neurotransmitter:sodium symporter MhsT has two substrate sites. (Mus musculus) PubMed

 21757.

These results demonstrate that HpNikR can directly respond to changes in cytosolic pH during acid acclimation and illustrate the exquisitely coordinated regulatory networks that support H. pylori infections in the harsh environment of the human stomach. (Mus musculus) PubMed

 21758.

the DUF266-containing gene OsPLS3 plays an important role in the onset of leaf senescence, in part through cytokinin and ethylene signaling in rice.[OsPLS3] (Mus musculus) PubMed

 21759.

the present findings indicate the connection of OsMATE2 in Arsenic accumulation, and could expand the functional role of MATE proteins in planta.[OsMATE2] (Mus musculus) PubMed

 21760.

OsERF101 is a gene that regulates dehydration responses during the vegetative and reproductive stages.[OsERF101] (Mus musculus) PubMed

 21761.

Mre11 complex links sister chromatids to promote repair of a collapsed replication fork (Mus musculus) PubMed

 21762.

AaKr-h1 directly binds to the regulatory regions of its target genes and acts as a transcriptional activator or a repressor in a promoter-specific manner.[kr-h1] (Mus musculus) PubMed

 21763.

Site-directed mutation assay revealed two amino acid changes in the R3 repeat, Arg/Lys(66) and Gly/Arg(93), responsible for functional divergence between two PpMYB10 genes.[PpMYB10.1, PpMYB10.2] (Mus musculus) PubMed

 21764.

Mutant deleted for the cof gene secreted significantly reduced levels of HlyA, had diminished hemolytic activity, and was impaired in its capacity to trigger human macrophage cell death and IL-1beta release.[HlyA, Cof] (Mus musculus) PubMed

 21765.

This study suggested that JH confers the competence to newly emerged female mosquitoes by regulating mRNA splicing to generate the Taiman isoforms that are essential for the vitellogenic 20E response. (Mus musculus) PubMed

 21766.

Ape0124 (NrnB) could degrade ssDNA and ssRNA from the 3'-end in the presence of Mn2+. Ape0124 prefers ssDNA, including short nanoDNA, and degrades nanoRNA with lower efficiency. The 3'-DNA backbone was found to be required for efficiently hydrolyzing the phosphodiester bonds. Ape0124 also degrads the 3'-overhang of double-stranded DNA. [gene Ape0124 (NrnB)] (Mus musculus) PubMed

 21767.

After feeding on double-stranded RNA specific for BtDnmt3, both heat resistance and cold resistance were significantly decreased, suggesting that BtDnmt3 is associated with thermal stress response and indicating a differential response to high- and low-temperature stress. [Dnmt3] (Mus musculus) PubMed

 21768.

The HaGBP precursor was found to be predominantly expressed in fat body, whereas HaGBPB1 and HaGBPB2 were mainly expressed in hemocytes. Immunological analyses indicated that both HaGBPB1 and HaGBPB2 are released from hemocytes into the plasma during the wandering stage. [GBP precursor, GBPB1, GBPB2] (Mus musculus) PubMed

 21769.

structural analysis unravels the crucial residues such as Tyr134, Lys145, Arg384 involve in the stability of the protein CYP51 (Mus musculus) PubMed

 21770.

Raf4 gene expression is induced by Aspergillus flavus and abiotic stresses.[Raf4] (Mus musculus) PubMed

 21771.

Zip1 expression is affected by zinc deficiency.[Zip1] IRT1 expression is affected by zinc deficiency.[Irt1] (Mus musculus) PubMed

 21772.

ORF19.1725 is involved in cell adhesion, penetration and virulence. [ORF19.1725 ] (Mus musculus) PubMed

 21773.

CP14019, CP16160 and CP16779 can degrade several chemokines, including CXCL1, CXCL2, CXCL3, IL-8, CCL2 and modulate immune responses during Giardia infections. [CP14019, CP16160 and CP16779 ] (Mus musculus) PubMed

 21774.

Values for the Michaelis-Menten kinetics parameters towards 4-nitrophenyl alpha-D-glucopyranoside (alpha-pNPG) substrate were estimated to be 0.44 mM (Km) and 1.9 s(-1) (kcat). Thin layer chromatography experiments established Cqm1 as alpha-glucosidase competent to cleave alpha-1,4-glycosidic bonds of maltose and maltotriose with high glycosyltransferase activity to form glucose-oligomers. (Mus musculus) PubMed

 21775.

CgCARDCP-1 might serve as a recognition molecule for LPS and a regulator of NF-kappaB activation in the immune response of oyster. [CARDCP-1] (Mus musculus) PubMed

 21776.

These assays revealed that recombinant glyceraldehyde-3-phosphate dehydrogenase (GAPDH) binds to the catalytic domain of Acp but not the cell wall binding domains. These results suggest that autolysin mediates expression of GAPDH on the surface of Clostridium perfringens cells.[GAPDH, Acp] (Mus musculus) PubMed

 21777.

Data demonstrate that the cooperation between the down-regulation of BmDnmt1 and increased stage-specific expression of BmDeaf1 enhances BmCHSA-2b tissue- and stage-specific transcription to ensure mid-wing development in B. mori. [DEAF1] (Mus musculus) PubMed

 21778.

PhABCC4 and perhaps CYP6CJ1 are involved in the Phase III and Phase I xenobiotic metabolism of ivermectin, respectively, and may play an important role in the evolution of ivermectin resistance in lice and other insects as field selection occurs.[ABCC4, CYP6CJ1] (Mus musculus) PubMed

 21779.

chaperone activities of ClpX are required to coordinate clock control of cell division whereas the protease activities of the ClpXP1P2 complex are required to maintain appropriate periodicity of the clock and its synchronization with the external environment. (Mus musculus) PubMed

 21780.

Arg1 regulates cell wall homeostasis and is crucial for cryptococcal virulence. (Mus musculus) PubMed

 21781.

Quantitative polymerase chain reaction results demonstrated that NlTsf1 was significantly higher than NlTsf2 or NlTsf3 in different tissues. All of them were expressed at higher levels in abdomen and head than in antenna, leg, stylet, and thorax. (Mus musculus) PubMed

 21782.

Dimeric protein HliC binds four chlorophyll molecules and two beta-carotenes.[HliC] (Mus musculus) PubMed

 21783.

This study demonstrates that the channel BtTRPA is important in temperature sensing and provides a molecular basis for thermosensation regulation in response to varied environmental temperature in B. tabaci Mediterranean (BtTRPA). (Mus musculus) PubMed

 21784.

This study investigated the development role of crinkled in postembryonic stages and indicated that forked mediates the functions of crinkled during wing morphogenesis in T. castaneum. [crinkled, forked] (Mus musculus) PubMed

 21785.

These results may underlie the discrepant function of CsTFL1b in cucumber from that in Arabidopsis.[CsTFL1b] (Mus musculus) PubMed

 21786.

the crystal structure of Sc5140 was determined and found to resemble the overall structure of other type-II LOGs.[Sc5140] (Mus musculus) PubMed

 21787.

Knockdown of circ_008018 attenuated cerebral ischemia-reperfusion-induced brain tissue damage and neurological deficits in mice by inducing microRNA miR-99a overexpression.[circ_00818] (Mus musculus) PubMed

 21788.

the crystal structure of the C-terminal functional domain of WA352 at 1.3A resolution, is reported.[WA352] (Mus musculus) PubMed

 21789.

High glucose induced histone H3K27 acetylation enrichment at the promoters of Nox1/4/5 genes in SMCs. The novel data of this study indicate that HDACs mediate vascular Nox up-regulation in diabetes. HDAC inhibition reduces vascular ROS production in experimental diabetes, possibly by a mechanism involving negative regulation of Nox expression. (Mus musculus) PubMed

 21790.

a trans-Golgi network localized transporter involved in manganese tolerance - [MTP11] (Mus musculus) PubMed

 21791.

Staphylopine/metal binding triggers a notable interdomain conformational change in CntA.[CntA] (Mus musculus) PubMed

 21792.

The hydrophobic region region of CyaA-Hemolysin is conceivably required for not only membrane-pore formation but also functional association with CyaC-acyltransferase, and hence effective palmitoylation at Lys(983).[CyaA, CyaC] (Mus musculus) PubMed

 21793.

ZmpC deletion mutant exhibited increased invasion of the brain and was associated with increased matrix metalloproteinase-9 in plasma and mortality as compared with the wild type.[ZmpC] (Mus musculus) PubMed

 21794.

Multiple mutations such as V1476G, P980S, and F382Y in RPA190 contribute to metalaxyl resistance, and resistance to metalaxyl can emerge in at least two independent pathways in P. infestans. [RPA190] (Mus musculus) PubMed

 21795.

The treatment of RAW264.7 cells with high glucose and free fatty acids increased the expression of LncRNA uc.48+, which evoked P2X7R-mediated immune and inflammatory responses through several pathways, including cytokine secretion. [LncRNA uc.48+] (Mus musculus) PubMed

 21796.

Here the authors present crystal structures revealing the MCR-1 periplasmic, catalytic domain to be a zinc metalloprotein with an alkaline phosphatase/sulphatase fold containing three disulphide bonds.[MCR-1] (Mus musculus) PubMed

 21797.

Coevolution of physicochemical properties in pairs of amino acid residues in the formamidopyrimidine-DNA glycosylase (Fpg) protein family was analyzed. 3 conserved polar bridges (Arg54-Glu131, Gln234-Arg244, and Tyr170-Ser208 in the E. coli protein) located in known functional regions of the protein were identified, and their roles were analyzed by site-directed mutagenesis. (Mus musculus) PubMed

 21798.

the high resolution crystal structure of ld-carboxypeptidase from E. coli, and demonstrate the dimeric structure is highly conserved.[Ldca} (Mus musculus) PubMed

 21799.

UMP kinase plays an essential role in chloroplast development and regulating chloroplast ATPase biogenesis in rice.[UMP kinase] (Mus musculus) PubMed

 21800.

phosphorylation of Lif1 by CK2 at a DNA double strand break site promotes the Lif1-Xrs2 interaction and facilitates Canonical-non-homologous end joining.[Lif1, Xrs2, Cka2] (Mus musculus) PubMed

 21801.

The cyanobacterial ribosomal-associated protein LrtA from Synechocystis sp. PCC 6803 is an oligomeric protein in solution with chameleonic sequence properties. [LrtA] (Mus musculus) PubMed

 21802.

ZmCOL3 acts as an inhibitor of flowering either by transactivating transcription of ZmCCT, one of the key genes regulating maize flowering, or by interfering with the circadian clock.[ZmCOL3, ZmCCT] (Mus musculus) PubMed

 21803.

the trans-splicing activity of FrpC resulted in covalent linkage of the FrpC1-414 fragment to plasma membrane proteins of epithelial cells in vitro, suggesting that formation of the FrpD-FrpC1-414 complex may be involved in the interaction of meningococci with the host cell surface. (Mus musculus) PubMed

 21804.

Osh6p provides an ideal endoplasmic reticulum membrane environment for Alk proteins to have a functional conformation via lipid transport activity in Y. lipolytica.[Osh6p, Alk1] (Mus musculus) PubMed

 21805.

miR-26b-5p interacted with 3'UTRs of Col1a2 and CTGF, and circ_000203 could block the interactions of miR-26b-5p and 3'UTRs of Col1a2 and CTGF.[Circrna_000203] (Mus musculus) PubMed

 21806.

molecular dynamics simulations of DHBPS-D-ribulose 5-phosphate complex along with magnesium [Mg(2+)] have shown entry of Mg(2+) from bulk solvent into active site.[DHBPS] (Mus musculus) PubMed

 21807.

Candida albicans strains deleted in their orthologs, CaFEN1 and CaFEN12, respectively, also showed comparable phenotypes, and a strain deleted for both these genes was extremely sensitive to cell wall perturbing agents.[CaFEN1, CaFEN2] (Mus musculus) PubMed

 21808.

The GapC protein of Staphylococcus aureus is a surface protein that is highly conserved among Staphylococcus strains, and it can induce protective humoral immune responses. (Mus musculus) PubMed

 21809.

Results suggest that through recognizing specific histones marks, Ibd1 targets active chromatin regions of highly expressed genes in Tetrahymena where it subsequently might coordinate the recruitment of several chromatin-remodeling complexes to regulate the transcriptional landscape of vegetatively growing Tetrahymena cells. [ibd1] (Mus musculus) PubMed

 21810.

Virus-induced gene silencing of the Dn resistance 1 (Adnr1) in a resistant wheat line resulted in the abolishment of the resistance response and induced a highly susceptible phenotype. The presence of the Adnr1 is necessary for Dn1 resistance. (Mus musculus) PubMed

 21811.

plausible candidate for Al tolerance - [MATE2] (Mus musculus) PubMed

 21812.

Our findings identify polyphosphate kinase as a novel negative regulator of virulence gene expression in F. tularensis [Polyphosphate Kinase]. (Mus musculus) PubMed

 21813.

This study identified a novel mutation in the promoter of KIAA1462 gene which can modulate glucocorticoid receptor binding affinity and affect the laying performance of geese. [glucocorticoid receptor, KIAA1462] (Mus musculus) PubMed

 21814.

Inhibition of LINC00652 decreased cardiac pathology, infarct size, apoptosis rates of myocardial cells, and levels of IL-1 beta and TNF-alpha, and increased GLP-1R expression cardiac function, normal hemodynamic index, and the expression and phosphorylation of GLP-1R and CREB proteins. (Mus musculus) PubMed

 21815.

Functional diversification of the NleG effector family in enterohemorrhagic Escherichia coli. (Mus musculus) PubMed

 21816.

ClfA binds with AnnexinA2 and this interaction could mediate S. aureus invasion into bovine mammary epithelial cells. (Mus musculus) PubMed

 21817.

Overexpression of miR171b increased the chlorophyll content of transgenic Broccoli. [Mir171b] (Mus musculus) PubMed

 21818.

Vibrio vulnificus CurA ( VvCurA) with 87% sequence similarity to the E. coli CurA exhibits the curcumin-reducing activity. [CurA] (Mus musculus) PubMed

 21819.

Influenza hemagglutinin membrane anchor. (Mus musculus) PubMed

 21820.

The KIX:c-Myb:HBZ complex provides an example of cooperative stabilization in a transcription factor:coactivator network and gives insights into potential mechanisms through which HBZ dysregulates hematopoietic transcriptional programs and promotes T cell proliferation. (Mus musculus) PubMed

 21821.

the salivary protein in brown planthopper, BPH, NlSEF1, functions as an effector and plays important roles in interactions between BPH and rice by mediating the plant's defense responses.[NlSEF1] (Mus musculus) PubMed

 21822.

Sulfopyruvate was the preferred substrate using the reduction reaction, with 31% activity seen for oxaloacetate and 0.2% seen for alpha-ketoglutarate. Optimal activity was observed at pH 6.5.[ComC] (Mus musculus) PubMed

 21823.

encodes a RING finger domain protein which negatively regulates drought stress tolerance in transgenic Arabidopsis - [DIS1] (Mus musculus) PubMed

 21824.

Ectopic expression in Arabidopsis enhances resistance to powdery mildew, improves osmotic stress resistance, and increases abscisic acid sensitivity - [WRKY42] (Mus musculus) PubMed

 21825.

Knocking-down the expression of SSSII-2 retained the transparent endosperm under low moisture conditions.[SSSII-2] (Mus musculus) PubMed

 21826.

This study investigates the primary aspects of oxidized flavin cofactor (FAD) photoreduction by ultrafast transient absorption spectroscopy, using the class II photolyase from Methanosarcina mazei. [class II photolyase] (Mus musculus) PubMed

 21827.

we discovered that GoGID1 can interact with the DELLA proteins of Arabidopsis in the presence of gibberellic acid (Mus musculus) PubMed

 21828.

Together our findings support a function of NcZrg-17 in normal vegetative growth, tolerance to ER stress and degradation of cellulose under low zinc conditions in N. crassa. (Mus musculus) PubMed

 21829.

These results provide genetic evidence for the involvement of GDP-mannose pyrophosphorylase (GMP) genes in the biosynthesis of mannose-containing polysaccharides and the mediation of GMP genes in the response to salt stress during seed germination and seedling growth.[GMP1] (Mus musculus) PubMed

 21830.

The role of a novel and conserved Plasmodium berghei protein encoded by PBANKA_091090 in maturation of Exo-erythrocytic Forms (EEFs) is examined and designated it as Sporozoite surface Protein Essential for Liver stage Development (PbSPELD).[SPELD] (Mus musculus) PubMed

 21831.

MT2 receptor mediated the stimulatory effects of melatonin on porcine cumulus expansion. (Mus musculus) PubMed

 21832.

alpha7 nAChR may play an important role in neuropathology caused by gp120.[gp120] (Mus musculus) PubMed

 21833.

phoPQ genes are important during chicken infection.[phoP,phoQ] (Mus musculus) PubMed

 21834.

K2P17.1 (TASK-4, TALK-2) two-pore-domain potassium (K2P) channels were identified, cloned, and functionally characterized as potassium-selective open rectifiers similar to their human orthologs. (Mus musculus) PubMed

 21835.

These findings show that production of TosR affected the expression of genes involved with adhesins, including P, F1C, and Auf fimbriae, nitrate-nitrite transport, microcin secretion, and biofilm formation.[TosR] (Mus musculus) PubMed

 21836.

SDG721 and SDG705 regulate H3K4 methylation, which is crucial for plant development in rice.[SDG721, SDG705] (Mus musculus) PubMed

 21837.

The authors identified a novel alternative transcript of CYP6ER1 (transcript A2) that had different expression patterns between imidacloprid-resistant and -susceptible populations, and was more stable after insecticide induction. (Mus musculus) PubMed

 21838.

The role of PsbO succinylation in the bacterial growth growth, photosynthesis and electron transport.[PsbO] (Mus musculus) PubMed

 21839.

Altogether, these results revealed that TbTim9, TbTim10, and TbTim8/13 interact with each other, associate with TbTim17, and play a crucial role in the integrity and maintenance of the levels of TbTim17 complexes.[ TbTim9, TbTim10, TbTim8/13, TbTim17] (Mus musculus) PubMed

 21840.

Study identifies a new binding site and a new binding partner for E. coli SSB protein. 18 amino acids (152-169) region of SSB located within intrinsically disordered region seems to be involved in the AlkB interaction. [ALKB, SSB] (Mus musculus) PubMed

 21841.

LdIscU and Fe-S proteins activity is significantly upregulated in resistant isolates and during stationary growth stage indicating an association between them. The differential expression of LdIscU modulated by Fe-S proteins demand suggests its potential role in parasite survival and drug resistance. (Mus musculus) PubMed

 21842.

identification and functional validation in development and stress mitigation roles - [LTP40 and LTP75] (Mus musculus) PubMed

 21843.

WTG1 was mapped onto the short arms of group 7 chromosomes. Multiple alignments indicated that WTG1 possesses eight exons and seven introns. An exon-intron junction composed of intron 2 to intron 3 and exon 2 to exon 4 was highly conserved. Drought and heat stresses significantly regulated the expression of TaWTG1 in wheat. [WTG1] (Mus musculus) PubMed

 21844.

Highly thermostable Lpn1 is active mainly towards RNA and ssDNA, with pH optima 7.0 and 6.0, respectively, with low activity towards dsDNA; the enzyme features pronounced substrate inhibition. Bioinformatic and experimental analysis, together with computer modeling and electrostatics calculations point to an unusually high positive charge on the enzyme surface under optimal conditions for catalysis. Lpn1. (Mus musculus) PubMed

 21845.

SpsQ stimulated the production of antibodies in dogs that specifically reacted with SpsQ and greatly diminished its cytotoxic effect on canine B cells. [SpsQ] (Mus musculus) PubMed

 21846.

Thermus thermophilus HB27, has two 2-isopropylmalate synthase homologous genes: TTC0847 and TTC0849, both of which are in the branched-chain amino acid biosynthetic gene cluster. [2-isopropylmalate synthase] (Mus musculus) PubMed

 21847.

ComB complex, present in the bacterial wall and essential for DNA uptake, can be a limiting factor for transformation efficiency.[ComB] (Mus musculus) PubMed

 21848.

DnaK significantly impacts the hierarchical order of carbon sources utilization, the excretion of main coproducts and the distribution of metabolic fluxes, thus revealing a multilevel interaction of DnaK with the central metabolism.[DnaK, DnaJ] (Mus musculus) PubMed

 21849.

OsBT1-3 likely acts as a plastid nucleotide uniporter and is essential for chloroplast development in rice leaves at the young seedling stage.[OsBT1-3] (Mus musculus) PubMed

 21850.

Altogether, the authors reveal that Pseudomonas aeruginosa protease IV potentiate pneumococcal pneumonia in a murine model of lung infection. (Mus musculus) PubMed

 21851.

Intrinsic structural versatility of the highly conserved 412-423 epitope of the Hepatitis C Virus E2 protein. (Mus musculus) PubMed

 21852.

Aip1 plays a major role in shaping the intranuclear rods.[Aip1] (Mus musculus) PubMed

 21853.

The Long Non-Coding RNA CYP4B1-PS1-001 interacts with nucleolin, and CYP4B1-PS1-001 inhibits the proliferation and fibrosis of MMCs depending on interaction with nucleolin and degradation of CYP4B1-PS1-001-associated nucleolin was mediated by a ubiquitin proteasome-dependent pathway. (Mus musculus) PubMed

 21854.

Results reveal that lncRNA MALAT-1 is not only widely expressed during the embryonic development of zebrafish but also in various organs of adult fish such as brain, eyes, heart, and muscle. Also, MALAT-1 was found highly expressed in the embryonic or adult nervous system of zebrafish. [lncRNA MALAT1] (Mus musculus) PubMed

 21855.

The authors determined that Clostridium difficile GerS, CwlD, and PdaA are all required to generate muramic-delta-lactam.[GerS, CwlD, and PdaA] (Mus musculus) PubMed

 21856.

Lrc-SV2 is a complementary gene to LrSV2 and is involved in leaf rust resistance [Lrc-SV2] (Mus musculus) PubMed

 21857.

mapping of Sen2 potato wart resistance gene; Sen2 provides resistance to 8 pathotypes of Synchytrium endobioticum [Sen2] (Mus musculus) PubMed

 21858.

Subsequent analyses demonstrated that the mannose-sensitive hemagglutinin (MshA) is crucial for attachment of Vibrio cholerae in the pharynx of the worm and initiation of colonization, which results in growth retardation and developmental delay of Caenorhabditis elegans.[MshA] (Mus musculus) PubMed

 21859.

Here, the authors demonstrate for the first time that the two distinct pathways leading to biofilm formation and biofilm drug tolerance are under the control of two sets of amino acid residues located within the HmsP sensory domain of SagS.[SagS] (Mus musculus) PubMed

 21860.

The results revealed that 988 genes were regulated in Delta TgTCTP compared with the complement strain. Overall, although not essential, TgTCTP is required for the fast growth of Tg and maintenance of its intracellular development. (Mus musculus) PubMed

 21861.

Study identified a DNA segment of chicken chromosome 3, namely OvoDBbeta, as a new member of chicken OvoD family. Molecular cloning, structure prediction, tissue expression and phylogenetic analyses indicated that OvoDBbeta was similar to other bird OvoDs with a potential antimicrobial property. [OvoDBbeta] (Mus musculus) PubMed

 21862.

diagnostic genetic markers were developed for the QTL region containing Fhb1, a Fusarium head blight resistance gene [Fhb1] (Mus musculus) PubMed

 21863.

Single-genome knock-out mutants of TaGW2 homoeologues increase both grain size and weight [TaGW2] (Mus musculus) PubMed

 21864.

Major A1 cytoplasm fertility restoration loci, Rf2 and Rf5 , were found in the West African sorghum. A potential causative mutation for Rf2 was identified. [Rf2; Rf5] (Mus musculus) PubMed

 21865.

Molecular cloning of CLCA3 from Xenopus laevis; results suggest that CLCA3 may be a candidate CLCA family member as well as a metalloprotease, rather than just an ion channel accessory protein [CLCA3] (Mus musculus) PubMed

 21866.

P69 binding to GLK proteins may interfere with the interaction between GLK proteins and upstream transcription factors, causing defective binding of GLK proteins to their targets.[P69] (Mus musculus) PubMed

 21867.

wool fibre from homozygous AA sheep have a higher mean fibre curvature than does the wool fibre from sheep carrying the TT genotype of the KAP20-2 gene [KAP20-2] (Mus musculus) PubMed

 21868.

The t(6)A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans. [PrrC] (Mus musculus) PubMed

 21869.

NMR and MS approaches were used to determine the glycan structure, and then a combination of NMR and molecular dynamics simulations were employed to characterize the impact of the glycan on the conformation and motions of the intrinsically flexible F-box-binding domain of Skp1. [Skp1, F-box protein] (Mus musculus) PubMed

 21870.

Enzymatic activity measurements and conformational dynamics studies monitored by NMR and molecular dynamic simulations show that E101G mutation of thioredoxin results in a small effect in the structural features of the protein.[EcTrx] (Mus musculus) PubMed

 21871.

The importance of amino acids Leu135 and Tyr236 for the interaction between heterotetrameric cleavage factor CFIm25 and RNA has been demonstrated. [CFIm25] (Mus musculus) PubMed

 21872.

OqxAB and MacAB efflux pumps and the transcriptional regulator RamA were involved in K. pneumoniae eravacycline resistance and heteroresistance. [OqxA,OqxB, MacA, MacB] (Mus musculus) PubMed

 21873.

AOX1 and AOX2 can promote the biofilm formation.[AOX1, AOX2] (Mus musculus) PubMed

 21874.

The pro-apoptotic protein Bax is main effector of mitochondrial permeabilization during apoptosis. Data suggest that human BAX N-terminal acetylation by yeast Naa20p/Nat3 is involved in mitochondrial targeting of Bax. These studies used recombinant human BAX expressed in yeast cells. (BAX = apoptosis regulator BAX) [Nat3, peptide alpha-N-acetyltransferase complex B subunit Nat3] (Mus musculus) PubMed

 21875.

bHLH142 regulates various metabolic pathway-related genes to affect pollen development and anther dehiscence in rice. [bHLH142] (Mus musculus) PubMed

 21876.

Taken together, these results indicate that this Mcp is responsible for the chemotactic response towards arsenites and is regulated by AioR.[AioR] (Mus musculus) PubMed

 21877.

Allorecognition and cell death are dependent upon physical interaction between SEC-9 and PLP-1. [SEC-9 and PLP-1] (Mus musculus) PubMed

 21878.

pH-dependent clcA expression is controlled by the LysR-type activator AphB, which acts in concert with AphA to initiate the virulence cascade in V. cholerae after oral ingestion. [clcA] (Mus musculus) PubMed

 21879.

Several sites of O2 molecules within a hydrophobic tunnel network leading, via two tunnel entrances, to the catalytic center of MBH. [MBH] (Mus musculus) PubMed

 21880.

4-bp insertion within ZmPLA1 results in a rare allele causing haploid induction.[ZmPLA1] (Mus musculus) PubMed

 21881.

Using single-molecule fluorescence resonance energy transfer, this study shows that the Escherichia coli DnaB helicase interacts specifically with the excluded DNA strand during unwinding. [DnaB helicase] (Mus musculus) PubMed

 21882.

In this study, lines that were nearly isogenic at the Rf4 locus were developed for comparative transcriptome analysis to uncover its function (Rf4) (Mus musculus) PubMed

 21883.

The role of MYB1 as a regulator of lignin and suberin biosynthesis, transport and assembly.[MYB1] (Mus musculus) PubMed

 21884.

the expression of IrGST1 in tick midgut functions as intracellular buffer of labile haem pool to ameliorate its cytotoxic effects upon haemoglobin intracellular hydrolysis. (Mus musculus) PubMed

 21885.

Thus, the C1 domain of STAC3 is responsible for its stable incorporation into the voltage-sensor (CaV1.1) of excitation-contraction-coupling complex, whereas the SH3 domain containing the Native American myopathy mutation site may be involved in low-affinity functional interactions in excitation-contraction-coupling.[CaV1.1] (Mus musculus) PubMed

 21886.

Omp-Pst1 and Omp-Pst2 can self-associate through their extracellular loops, forming dimers of trimers that could enable cell-to-cell contact within floating communities.[Omp-Pst1,Omp-Pst2] (Mus musculus) PubMed

 21887.

The NrdJd-type Ribonucleotide reductases from the bacterium Stackebrandtia nassauensis was used as a model enzyme. A novel cysteine-rich C-terminal domain is involved in both higher oligomeric state formation and electron transfer to the active site. [NrdJd] (Mus musculus) PubMed

 21888.

transmembrane possibility and the glycosylphosphatidylinositol -anchoring possibility of OsCEBiP, are reported.[OsCEBiP] (Mus musculus) PubMed

 21889.

As cells age, Hcm1 is rapidly excluded from the nucleus in young cells, blocking the expression of Hcm1 targets.[Hcm1] (Mus musculus) PubMed

 21890.

This study presents a 0.95-A resolution X-ray structure of H. jecorina cellulose-degrading enzyme HjLPMO9A, belonging to the AA9 family of lytic polysaccharide monooxygenases. [LPMO9A] (Mus musculus) PubMed

 21891.

This study reveals that Gp90 exo(-) preferentially inserts A opposite an abasic site via the A-rule, like other DNA polymerases (e.g., Pol theta;, KlenTaq, KF exo(-), Pols alpha, delta/PCNA, and Thermococcus litoralis Pol Vent (exo(-))), providing further insight into DNA replication mediated by P. aeruginosa phage PaP1 upon encountering an abasic site lesion. (PaP1 protein) (Mus musculus) PubMed

 21892.

IpdAB opens the last steroid ring of cholesterol by acting as a hydrolase and the glu105(A) conserved in the alpha-subunit was essential for catalysis.[IpdAB] (Mus musculus) PubMed

 21893.

the crystal structure of DapF from Corynebacterium glutamicum, is reported.[DapF] (Mus musculus) PubMed

 21894.

Substitution of MgtC tryptophan 226(th) residue to alanine, glycine, or tyrosine leads to MgtC proteolysis in a manner dependent on the FtsH protease whereas substitution to phenylalanine, methionine, isoleucine, leucine, or valine resists MgtC degradation by FtsH. These data indicate that a large and hydrophobic side chain at 226(th) residue is required for protection from the FtsH-mediated MgtC proteolysis.[MgtC, FtsH] (Mus musculus) PubMed

 21895.

Deletion of hofQ from the A. actinomycetemcomitans genome decreased the overall biofilm formation of this organism, abolished the response to cytokines, i.e., decreased eDNA levels in the presence of cytokines, and increased the susceptibility of the biofilm to tested beta-lactams [hofQ]. (Mus musculus) PubMed

 21896.

These results provide the first experimental evidence of an essential role for HSP90 in Notch signaling in development.[DAf-21] (Mus musculus) PubMed

 21897.

conclude that Nolz1 has multiple functions during development and suggest a mechanism in which Nolz1 initially regulates the proliferation state of the retinal progenitor cells[nolz1] (Mus musculus) PubMed

 21898.

CdiA protein play a role in growth inhibition but not in biofilm formation or adherence to epithelial cells. [CdiA] (Mus musculus) PubMed

 21899.

HIR2/HIR4 proteins repress anthocyanin accumulation by interacting with the JAZ2 protein to inhibit its degradation in apples. [HIR2], [HIR4] (Mus musculus) PubMed

 21900.

These data suggest that chw-1 is likely acting downstream and/or in parallel to sax-3 in axon guidance.[CHW-1] (Mus musculus) PubMed

 21901.

These results provide novel mechanistic insights into Hif1 functions and establish it as an important protein in chromatin-associated processes.[Hif1] (Mus musculus) PubMed

 21902.

Upon hydrogen peroxide, the nuclear retention of PKA catalytic subunits, which contributes to delayed Msn2 nuclear concentration, is antagonized in a Tsa1-dependent manner.[Tsa1] (Mus musculus) PubMed

 21903.

exopolysaccharide recognition is reiterated during the progressing infection and that EPR3 perception of compatible exopolysaccharide promotes an intracellular cortical infection mechanism maintaining bacteria enclosed in plant membranes.[EPR3] (Mus musculus) PubMed

 21904.

the physiological role of Cse4 K65 in sumoylation, ubiquitin-mediated proteolysis, and localization of Cse4 for genome stability, are reported.[Cse4] (Mus musculus) PubMed

 21905.

X-ray crystal structure of Omp33 is reported at a resolution of 2.1 A. Omp33 has a 14-beta-stranded barrel without stable extracellular loop constrictions. Instead, an extended and unusual periplasmic turn connecting beta-strands 2 and 3 is present, which folds into the pore lumen and completely blocks the aqueous channel. [Omp33] (Mus musculus) PubMed

 21906.

Results suggest that different metallothioneins functionally compensated in Tetrahymena, and that MTT5 was a potential candidate for cadmium and lead bioremediation. [MTT5] (Mus musculus) PubMed

 21907.

GDH2 promotes growth of IDH1-expressing gliomas.The role of GDH2 allosteric domain in regulating IDH1 metabolic changes in glioma.[GDH2] (Mus musculus) PubMed

 21908.

The transmembrane domain of EssB is critical for heterodimerization with EsaA.[ EssB, EsaA] (Mus musculus) PubMed

 21909.

D. radiodurans encodes a fused molybdopterin synthase synthase, MoaD-MoaE fusion protein DR2607. JAMM/MPN+ metalloprotease DR0402 (JAMMDR) can cleave the MoaD-MoaE fusion. JAMMDR recognizes the MoaD region in the cleavage process of MoaD-MoaE fusion. [MoaD-MoaE fusion protein , JAMMDR] (Mus musculus) PubMed

 21910.

Srs2 helicase activity plays a more central role in DNA repair.[Srs2] (Mus musculus) PubMed

 21911.

crystal structure of a fragment of the SidE family member SdeA that retains ubiquitination activity, and determine the mechanism of this unique post-translational modification [SdeA] (Mus musculus) PubMed

 21912.

structure of the catalytic core of SdeA, comprising mono-ADP-ribosyltransferase (mART) and phosphodiesterase (PDE) domains, shedding light on the activity of two distinct catalytic sites for serine ubiquitination (Mus musculus) PubMed

 21913.

Extracellular PHBC (polyhydroxybutyrate polymerase) is involved in abiotic stress response in plants.[PHBC] (Mus musculus) PubMed

 21914.

This study found DGTT3 to have a significant response to low temperatures, phosphorus deficiency, and other stresses, such as high concentrations of NaCl, 20 muM GA, and 20 muM abscisic acid. Deletion and scanning mutagenesis analyses revealed that the - 319/- 247 region is essential for low-temperature and phosphate-deficiency-mediated induction of DGTT3 expression.[DGTT3] (Mus musculus) PubMed

 21915.

PI3K domain of Tra1 is directly or indirectly important for incorporating Tra1 into SAGA and NuA4 and thus the biosynthesis and/or stability of the intact complexes.[Tra1] (Mus musculus) PubMed

 21916.

The DEF1 attenuator behaved as a hybrid terminator, relying heavily on cleavage and polyadenylation factor and Sen1 but without Nrd1 and Nab3 involvement.[DEF1, Sen1] (Mus musculus) PubMed

 21917.

Rsd and 6S RNA facilitate sigma(38) activity throughout bacterial growth, while 6S RNA also regulates widely different genes depending upon growth phase.[Rsd] (Mus musculus) PubMed

 21918.

Overall, these results indicate that SBP1 is an adhesion-associated factor without the involvement of virulence in Streptococcus suis serotype 2.[SBP1] (Mus musculus) PubMed

 21919.

our results uncover an accumulation of abnormal levels of single-stranded DNA (ssDNA) and the Rad52 repair protein at de-regulated origins. We show that these loci constitute a defining source of the overall ssDNA and Rad52 hotspots in the genome, generating a signature pattern of instability along the chromosomes. (Mus musculus) PubMed

 21920.

the characterization of a novel mutant variant of the eukaryotic AAA-ATPase Drg1 that shows dysregulation of ATPase activity and altered interaction with Rlp24, its substrate in ribosome biogenesis, is reported.[Drg1] (Mus musculus) PubMed

 21921.

These results establish Vps74 as a novel regulator of telomere biology.[Vps74] (Mus musculus) PubMed

 21922.

The authors analyze the CA sequences of CO2-dependent and -independent brucellae and spontaneous mutants. The comparisons strongly suggest that CAII is not functional in CO2-dependent B. abortus and B. ovis, and that a modified CAII sequence explains the CO2-independent phenotype of spontaneous mutants. They also prove that CAI alone is not enough to support CO2-independent growth of B. abortus in rich media.[CAI,CAII] (Mus musculus) PubMed

 21923.

The authors analyze the CA sequences of CO2-dependent and -independent brucellae and spontaneous mutants. The comparisons strongly suggest that CAII is not functional in CO2-dependent B. abortus and B. ovis, and that a modified CAII sequence explains the CO2-independent phenotype of spontaneous mutants.[CAI,CAII] (Mus musculus) PubMed

 21924.

These data indicate that activation of DAF-16/FOXO3A is a highly conserved response to genotoxic stress that is important for suppressing consequent oxidative stress. Correspondingly, dysregulation of DAF-16/FOXO3A appears to underpin shortened healthspan and lifespan, rather than the increased DNA damage burden itself. [FOXO3A] (Mus musculus) PubMed

 21925.

Data show unique features of FhuD to bind both hydroxamate and catecholate type xenosiderophores. However, slightly basic ligand binding pocket of FhuD could favor ferri-enterobactin binding with R203, along with R102. Also, study indicates parallel binding of two heme molecules to HutB in a pH dependent manner, while mutational analysis established the relative importance of Y65 and H164 in heme binding. [FhuD and HutB] (Mus musculus) PubMed

 21926.

Transcriptome analysis was performed in a collection of Zea mays lines carrying mutant alleles for CMT or -directed DNA methylation-associated genes.[CMT] (Mus musculus) PubMed

 21927.

These findings suggest that LotS/LotR/SmtP play an important role in responding to temperature stimuli via c-di-GMP mediated manner.[LotS, LotR, SmtP] (Mus musculus) PubMed

 21928.

Study uncovered the molecular activity of AtaT: it specifically acetylates the methionine moiety on the initiator Met-tRNAfMet. This modification drastically impairs recognition by initiation factor 2, thereby inhibiting the initiation step of translation. [AtaT] (Mus musculus) PubMed

 21929.

The Rec8 homoeoalleles from the subgenomes A and D are transcriptionally more active than the one from the subgenome B in polyploid wheat. [Rec8] (Mus musculus) PubMed

 21930.

PUB13 is an E3 ligase with a positive regulatory role during the initial stages of nodulation in L. japonicus. [PUB13] (Mus musculus) PubMed

 21931.

CPH1 contains ankyrin repeats that are required for structural integrity of the conoid, parasite motility, and host cell invasion. Proximity labeling and protein interaction network analysis reveal that CPH1 functions as a hub linking key motor and structural proteins that contain intrinsically disordered regions and coiled coil domains. (Mus musculus) PubMed

 21932.

MntR crystal structure revealed two manganese binding sites.[MntR] (Mus musculus) PubMed

 21933.

identified Spa10, a member of a recently described family of septal pore-associated proteins, as a first protein that directly or indirectly interacts with LahC to allow a stable positioning of Woronin bodies at the mature septum. (Mus musculus) PubMed

 21934.

this study demonstrates that GlcNAc6ST-1 modulates peripheral nervous system myelination and myelinated axonal survival.[GlcNAc6sT-1] (Mus musculus) PubMed

 21935.

The X. laevis Eco2 bound to its primary and secondary Smc3 substrates demonstrate the plasticity of the substrate-binding site, which confers substrate specificity by concerted conformational changes of the central beta-hairpin and the C-terminal extension. (Mus musculus) PubMed

 21936.

Repressor protein IolR avoids costs of untimely induction of myoinositol utilization by Salmonella Typhimurium. [IolR] (Mus musculus) PubMed

 21937.

Lactonase (AttM) affecting pathogenicity and/or virulence of scab-causing Streptomyces species. [AttM] (Mus musculus) PubMed

 21938.

The present study is the first to provide detailed information on the function of the N- and C-terminal segments in the interfacial binding of Vibrio parahaemolyticus Phospholipase D and improves the understanding of how this enzyme interacts with cell membranes. [Phospholipase D] (Mus musculus) PubMed

 21939.

key Scc2 surfaces that are crucial for cohesin loading in vivo, were identified.[scc2] (Mus musculus) PubMed

 21940.

MilR2 serves as an activator for 5-oxomilbemycin A3/A4 production and the function of MilR2 is only partially mediated through its repression on the transcription of sbi_00791. [MilR2] (Mus musculus) PubMed

 21941.

The recombinant prefoldin could not protect citrate synthase from thermal aggregation. However, it formed a complex with actin from chicken muscle and tubulin from porcine brain, suggesting substrate specificity. [prefoldin] (Mus musculus) PubMed

 21942.

Data reveal that RdlB is a new functional amyloid and provide a biophysical basis for the functional differences between the two rodlin (RdlA and B) proteins. [RdlB] (Mus musculus) PubMed

 21943.

genetic interactions of JHD2 and SET1 with essential genes involved in varied aspects of the transcription cycle, were examined.[JHD2, SET1] (Mus musculus) PubMed

 21944.

HDT701 induces flowering by suppressing OsIDS1.[HDT701, OsIDS1] (Mus musculus) PubMed

 21945.

Atg3 acetylation can promote the lipidation of Atg8.[Atg3, Atg8] (Mus musculus) PubMed

 21946.

HMGCR role in the statin resistance.[HMGCR] (Mus musculus) PubMed

 21947.

The role of KPC-2 in Serratia marcescens drug resistance and pathogenicity.[KPC-2] (Mus musculus) PubMed

 21948.

TCM1 is essential for proper chloroplast development and maintaining plastid-encoded polymerase activity under cold stress. [TCM1] (Mus musculus) PubMed

 21949.

substrate specificity of ExoY mainly depends on its ability to bind NTP in proper geometrical orientations[ExoY] (Mus musculus) PubMed

 21950.

ADA2 orchestrates the response of C. glabrata against reactive oxygen species-mediated immune defenses during infection.[Ada2] (Mus musculus) PubMed

 21951.

Comprised of just 17 residues, kappa-actitoxin-Ate1a (Ate1a) is the shortest sea anemone toxin reported to date, and it adopts a novel three-dimensional structure that we have named the Proline-Hinged Asymmetric beta-hairpin (PHAB) fold. [kappa-actitoxin-Ate1a ] (Mus musculus) PubMed

 21952.

DksA plays an important role in multi-drug resistance of E. coli, and directly or indirectly regulates the expression of several genes, including a number of genes related to resistance to several antibiotics.[DksA] (Mus musculus) PubMed

 21953.

These results suggest that the expression of Dnmt3 and global DNA methylation in the testis of ricefield eels are potentially down-regulated by Gonadotropin-releasing hormone, and reveal a novel regulatory mechanism of testicular Dnmt3 expression in vertebrates.[Gonadotropin-releasing hormone, Dnmt3] (Mus musculus) PubMed

 21954.

Pkc1 emerged as a novel node of PP2ACdc55 regulation, highlighting a major role of PP2ACdc55 in actin cytoskeleton and cytokinesis, gene ontology terms significantly enriched in the PP2ACdc55-dependent phosphoproteome.[PP2A-Cdc55] (Mus musculus) PubMed

 21955.

Data suggest that Gh42 exhibits alpha-L-arabinopyranosidase activity in this species isolated from human gut microbiome. [Gh42, alpha-L-arabinopyranosidase] (Mus musculus) PubMed

 21956.

Thymidylate synthase forms non-covalent bisubstrate intermediate during catalysis. [ thymidylate synthase] (Mus musculus) PubMed

 21957.

Isolated from China multidrug-resistant Shigella sonnei has plasmid-mediated Mcr-1 gene.[Mcr-1] (Mus musculus) PubMed

 21958.

Mutations in the mecA promoter region in the oxacillin-resistant Staphylococcus aureus isolates.[mecA] (Mus musculus) PubMed

 21959.

This study presents the structure of the PilZ adaptor protein MapZ cocrystallized in complex with c-di-GMP and its protein target CheR1, a chemotaxis-regulating methyltransferase in Pseudomonas aeruginosa. [PilZ adaptor protein MapZ] (Mus musculus) PubMed

 21960.

Results demonstrate that heterologous overexpression of PfVIT in E. coli confers increased resistance to iron-mediated cell death to the bacterial cells and that the PfVIT transport mechanism is Fe2+/H+ antiport driven by the proton electrochemical gradient. (Mus musculus) PubMed

 21961.

The model of Rae1 docked in the A-site allows us to make predictions about which conserved residues may be important for recognition of mRNA, the tRNA in the adjacent P-site and binding to the 50S ribosome subunit (Mus musculus) PubMed

 21962.

Deleting PMR1 in the parental XIylose isomerase-expressing strain enabled instantaneous anaerobic growth on d-xylose.[PMR1, XylA] (Mus musculus) PubMed

 21963.

Mcr-1, mcr-4 and mcr-5 co-expression in the multidrug-resistant ST10 Enterotoxigenic and Shiga toxin-producing Escherichia coli in Spain.[mcr-1] [mcr-4] [mcr-5] (Mus musculus) PubMed

 21964.

study reveals the mechanism of SdeA-mediated ubiquitin modification and provides a framework for further investigations into the phosphoribosyl-linked ubiquitination process (Mus musculus) PubMed

 21965.

The cis-12 LAI enzyme encoded by FgLAI12 is critical for fungal response to SA, mycelial growth and virulence in wheat.[LAI12] (Mus musculus) PubMed

 21966.

the conserved amino acid residues in the TRA-CAM domain may be crucial for the interaction between MdTRA and TRA-2, enhancing MdTRA recruitment on its pre-mRNA to induce female-specific splicing of tra in the housefly.[Tra] (Mus musculus) PubMed

 21967.

This study evaluated the efficacy of the B6-HRP ELISA for ovine pregnancy-specific protein B (PSPB) measurement in the detection of pregnancy and estimation of fetal numbers in different sheep breeds.[PSPB] (Mus musculus) PubMed

 21968.

Results of this study indicated that non-O1/non-O139 V. cholerae suppressed the growth of the O1 pandemic strain by using contact-dependent T6SS as well as by secreting the O1-detrimental hemolysin A during their co-persistence in the aquatic habitat. [HlyA] (Mus musculus) PubMed

 21969.

Cg1261 was found to form a hexamer.[Cg1261] (Mus musculus) PubMed

 21970.

Data suggest that AlmG, a glycyltransferase, is responsible for polymyxin resistance in this species. [AlmG, glycyltransferase-AlmG] (Mus musculus) PubMed

 21971.

Two small subunits, PBP1 and PBP2, associate with distinct surfaces of the larger catalytic subunit and influence the enzymatic properties of the DNA polymerase. [PPB1];[PBP2] (Mus musculus) PubMed

 21972.

The positive role of the WRKY67 in regulating rice responses to leaf blast, panicle blast and bacterial blight disease.[WRKY67] (Mus musculus) PubMed

 21973.

MiR390 induced by auxin triggers the lateral root growth under normal growth conditions.MiR393 and miR390 synergistically regulate lateral root growth in rice[Mir390] MiR393 is up-regulated by various stresses.[Mir393] (Mus musculus) PubMed

 21974.

GCNT acts as a negative-regulator mediating defense response and immunity-associated premature leaf senescence probably by activating jasmonate signaling pathway. [GCNT] (Mus musculus) PubMed

 21975.

Our results indicate that FtsZ polymerisation presides over the recruitment of the other cell division components, which occurs in two distinct steps. They further suggest that early pre-divisional Z-rings form between 40 and 50% of the cell cycle (Mus musculus) PubMed

 21976.

High prevalence of Mcr-1-positive E. coli in diseased pigs in Japan.Mcr-1 role in colistin resistance.[Mcr-1] High prevalence of Mcr-3-positive E. coli in diseased pigs in Japan.Mcr-3 role in colistin resistance.[Mcr-3] High prevalence of Mcr-5-positive E. coli in diseased pigs in Japan.Mcr-5 role in colistin resistance.[Mcr-5] (Mus musculus) PubMed

 21977.

We identify Wdr8 as a novel maternally essential protein that is required for centrosome assembly during embryonic mitoses of medaka. [Wdr8] (Mus musculus) PubMed

 21978.

Apicomplexan C-Mannosyltransferases Modify Thrombospondin Type I-containing Adhesins of the TRAP Family [MIC2] (Mus musculus) PubMed

 21979.

Apicomplexan C-Mannosyltransferases Modify Thrombospondin Type I-containing Adhesins of the TRAP Family [MIC2] (Mus musculus) PubMed

 21980.

Collectively, these results underscore the importance of MntC-dependent manganese transport in Staphylococcus aureus oxidative stress resistance and virulence. [MntC] (Mus musculus) PubMed

 21981.

MSD1 regulates pedicellate spikelet fertility in sorghum through the jasmonic acid pathway. [MSD1] (Mus musculus) PubMed

 21982.

The results of the present study demonstrate that B. microti thioredoxin 3 (BmTrx3) is a functional enzyme with antioxidant activity and may be involved in the response of B. microti to anti-parasite drugs [BmTrx3]. (Mus musculus) PubMed

 21983.

PtrMYB012 transcripts are down-regulated by miR159 in poplar but not in Arabidopsis. Indeed, subsequent 5'-RACE analysis confirmed that PtrMYB012 transcripts are completely degraded in poplar, probably by miR159, but not in Arabidopsis. These results suggest that species-specific family members of miR159 are important for the regulation of normal growth and development in plants. [MYB012] (Mus musculus) PubMed

 21984.

The predominant genotype in our population was cagA positive vacA s1, which was found to be significantly associated with patients with gastric diseases, especially PUD. VacA s1 can serve as a single best virulence marker of the disease manifestation [CagA]. (Mus musculus) PubMed

 21985.

Results clearly demonstrate that M. bovis can induce NET formation in bovine neutrophils, but that the major membrane nuclease MnuA is able to rapidly degrade NETs, and thus is likely to play a significant role in virulence [MnuA]. (Mus musculus) PubMed

 21986.

Involvement of PorK, a component of the type IX secretion system, in Prevotella melaninogenica pathogenicity.[Prevotella melaninogenica ] (Mus musculus) PubMed

 21987.

The results of this study suggest a role of PhoPR in M. bovis to be linked to the mechanisms that mycobacteria display to maintain their redox balance [PhoPR]. (Mus musculus) PubMed

 21988.

robust evidence that TgCrk9 is an important part of transcription machinery regulating gene expression in T. gondii. (Mus musculus) PubMed

 21989.

Deletion of both GIS2 and ZNF9 resulted in a modest increase in basal stability of the RPL2 mRNA which resulted in an association with higher-molecular-weight polysomes under unstressed conditions.[GIS2, ZNF9, RPL2] (Mus musculus) PubMed

 21990.

Taken together, these results indicated for the first time that PnuC is involved in the oxidative stress tolerance and virulence of S. suis 2 during infection [PnuC]. (Mus musculus) PubMed

 21991.

C6 can both diminish the production of interferon and inhibit interferon-induced signalling and thereby the expression of interferon-stimulated genes. [review] (Mus musculus) PubMed

 21992.

In a pulmonary tularaemia model, PYDC2 enhances Interferon-gamma production, modulates neutrophil numbers, improves macrophage functions, increases bacterial control and diminishes lung pathology. Thus, unlike other Pyrin domain-only proteins thought to diminish innate protection, PYDC2 reduces detrimental inflammation while preserving and enhancing protective immunity. [PYDC2] (Mus musculus) PubMed

 21993.

Global nitrogen regulator GlnR interacts with the promoter regions of the gene encoding lysine deacetylase and activates its transcription. Signal transduction mechanism of regulating protein deacetylation in response to extracellular nitrogen availability is mediated by the nutrient-sensing pleiotropic regulator GlnR. (Mus musculus) PubMed

 21994.

The authors show that the SUN domain protein Sad1 localizes close to kinetochores in interphase as well as in mitotic cells. Sad1 is nonessential for viability in C. neoformans but is required for proper growth and high-fidelity chromosome segregation. (Mus musculus) PubMed

 21995.

Together, these results demonstrate a procyclic-form-specific environmental lipid response pathway that regulates Trypanosoma brucei acetyl coenzyme A carboxylase (ACC) posttranscriptionally, through changes in protein expression and phosphorylation.[ACC] (Mus musculus) PubMed

 21996.

A novel antimicrobial peptide (LGH2) was identified from the genome of the L. casei HZ1. This peptide had a higher antimicrobial activity against S. aureus than the other bacteria. Also, LGH2 was found to bind to cell surface, disrupt cell membrane, and eventually lead to bacterial death. [LGH2] (Mus musculus) PubMed

 21997.

Data provide evidence that the YidC dimer contains two functional protomers although they can have some restrictive influence on each other. Each protomer is capable to bind one substrate protein and catalyzes its membrane insertion. [YdiC] (Mus musculus) PubMed

 21998.

IPA1 promotes both yield and disease resistance by sustaining a balance between growth and immunity. [IPA1] (Mus musculus) PubMed

 21999.

The authors identified a cDNA encoding the neurosecretory protein GM (NPGM) precursor in chickens. Morphological analysis showed that NPGM-containing cells are specifically localized in the medial mammillary nucleus (MM) and infundibular nucleus (IN) in the hypothalamus.[NPGM] (Mus musculus) PubMed

 22000.

Here we show that EspB not only constitutes an essential part of the T3SS-nanomachine and contributes to the arsenal of injected effector proteins but, furthermore, that secreted (recombinant) EspB autonomously enters host cells and selectively induces cell death in immune cells [EspB]. (Mus musculus) PubMed

 22001.

Replacing the transmembrane domain 3 sequence with an alternative hydrophobic sequence within the full-length EscR protein resulted in a complete loss of function of the type III secretion system, further suggesting that it has another functional role in addition to its role as a membrane anchor.[EscR] (Mus musculus) PubMed

 22002.

Escherichia coli expressing MCR-1.5 was isolated in Japan.[mcr-1.5] (Mus musculus) PubMed

 22003.

miR-181a promoted porcine preadipocyte differentiation by directly targeting TGFBR1. (Mus musculus) PubMed

 22004.

Mycobacterium smegmatis protein Rv2989 negatively regulates leuCD operon and induces dormancy-like growth arrest. (Mus musculus) PubMed

 22005.

OsNDUFA9 subunit of complex I is essential for embryo development and starch synthesis in rice endosperm.[OsNDUFA9] (Mus musculus) PubMed

 22006.

baculovirus LEF-11 hijacks the host ATPase family members, ATAD3A and HSPD1, efficiently promote the multiplication of the virus.[ATAD3A] (Mus musculus) PubMed

 22007.

OsPLDalpha1 gene overexpression resulted in a reduction in production loss under severe water deficit and revealed a possibility for the development of upland rice cultivars that are more tolerant to extreme drought conditions.[OsPLDalpha1] (Mus musculus) PubMed

 22008.

Constitutive high-level alpha-1,3-glucan synthase activity of Aspergillus nidulans increases hyphal wall thickness, but colonies grow slowly and sporulate poorly and have much higher adhesion to hydrophobic materials. This overexpression strain forms a biofilm-like structure in plastic culture wells that is as adhesive as wild-type Aspergillus fumigatus. (Mus musculus) PubMed

 22009.

The MinDE protein system from E. coli has recently been identified as a minimal biological oscillator, based on two proteins only: The ATPase MinD and the ATPase activating protein MinE. This study used high-speed atomic force microscopy to analyze the mechanism of MinDE membrane association/dissociation dynamics. [MinD, MinE] (Mus musculus) PubMed

 22010.

the dual function of Cas2 can be explained by a dynamic equilibrium of conformational states that serve as a scaffold or as a nuclease on demand (Cas2 protein) (Mus musculus) PubMed

 22011.

data reveal the determinants of LPMO stability under turnover and non-turnover conditions and indicate that the reduction of the active-site copper initiates substrate binding. (Mus musculus) PubMed

 22012.

Structure of the monotopic membrane protein (S)-mandelate dehydrogenase at 2.2A resolution. (Mus musculus) PubMed

 22013.

PBP2b plays a key role in both peripheral growth and septum positioning in Lactococcus lactis [PBP2b] (Mus musculus) PubMed

 22014.

OsJMJ703 is involved in abiotic stress.[OsJMJ703] (Mus musculus) PubMed

 22015.

positively regulates disease resistance by suppressing the ABA signaling pathway - [ONAC066] (Mus musculus) PubMed

 22016.

Comprehensive genomic analysis of the TYROSINE AMINOTRANSFERASE (TAT) genes in apple (Malus domestica) allows the identification of MdTAT2 conferring tolerance to drought and osmotic stresses in plants. (Mus musculus) PubMed

 22017.

Structural and functional insights into the role of BamD and BamE within the beta-barrel assembly machinery in Neisseria gonorrhoeae. (Mus musculus) PubMed

 22018.

Domain exchange experiments showed that the C-terminal periplasmic domain of MotS directly controls the assembly and disassembly dynamics of the MotPS stator in a load- and polysaccharide-dependent manner.[MotP,MotS] (Mus musculus) PubMed

 22019.

when expressed in the rice rss1 mutant, TdRL1 suppressed its dwarf phenotype upon salt stress, confirming that both proteins are true functional homologs required for salt stress tolerance in cereals.[TdRL1] (Mus musculus) PubMed

 22020.

when expressed in the rice rss1 mutant, TdRL1 suppressed its dwarf phenotype upon salt stress, confirming that both proteins are true functional homologs required for salt stress tolerance in cereals.[RSS1] (Mus musculus) PubMed

 22021.

Dms1 is required to initiate forespore membrane formation and maintain meiotic SPB components [Dms1] (Mus musculus) PubMed

 22022.

Rice auxin influx carrier AUX1 facilitates root hair elongation in response to low external phosphate. [AUX1] (Mus musculus) PubMed

 22023.

Study reports the X-ray structure of TrzD, a cyanuric acid hydrolase from Acidovorax citrulli. Results show a large displacement of the catalytic lysine (Lys163) in domain 2 away from the active site core that seems to open up a channel for product release. The structure also showed two molecules of the co-product, carbon dioxide, one in the active site and another trapped in the proposed exit channel. [TrzD] (Mus musculus) PubMed

 22024.

increase in mitochondrial damage and corresponding release of cytochrome c may be one of the major causes of endosperm apoptosis advancement under waterlogging.[Cytochrome c] (Mus musculus) PubMed

 22025.

Structural basis for substrate specificity of methylsuccinyl-CoA dehydrogenase, an unusual member of the acyl-CoA dehydrogenase family. (Mus musculus) PubMed

 22026.

Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S has been described. [EndoS] (Mus musculus) PubMed

 22027.

P7 is an intracellular proton-gated H +-channel. P7 activity induced production of interleukin IL-1beta in liver macrophages. [p7 protein] (Mus musculus) PubMed

 22028.

a correlation between elevated DGAT1 gene expression levels and higher oil content and oleic acid levels in rapeseed, is reported.[Dgat1, BnZFP1]] (Mus musculus) PubMed

 22029.

Tax signals were detected in infiltrating mononuclear cells and salivary ducts in HTLV-I-seropositive Sjogren's syndrome. (Mus musculus) PubMed

 22030.

Molecular structure of the cyclic nucleotide-modulated potassium channel MloK1 in a lipid bilayer has been described. [MloK1] (Mus musculus) PubMed

 22031.

PABP2 regulates bulk mRNA translation, as it interacts with a wide range of proteins, enters stress granules and distributes over the full range of polysomes. [PABP2] (Mus musculus) PubMed

 22032.

Here, a Streptococcus pneumoniae ABC transporter responsible for fluoroquinolones resistance in clinical settings, PatA/PatB, is shown to challenge this concept. It clearly favors GTP as the energy supply to expel drugs. This preference is correlated to its ability to hydrolyze GTP more efficiently than ATP.[PatA, PatB] (Mus musculus) PubMed

 22033.

A. baumannii has an ability to produce lectin protein; Lec gene was detected in A. baumannii. [lectin] (Mus musculus) PubMed

 22034.

Csa1G642540 might play an important role in regeneration in cucumber [Csa1G642540] (Mus musculus) PubMed

 22035.

These studies demonstrate that HMW2 adhesin binds 2-6 linked N-acetylneuraminic acid with high affinity. HMW2 did not bind glycan structures containing the non-human form of sialic acid, N-glycolylneuraminic acid. [HMW2 adhesin] (Mus musculus) PubMed

 22036.

high-resolution cryo-electron microscopy structure of a ternary complex of RBP2b bound to human TfR1 and transferrin, at 3.7 A resolution [reticulocyte-binding protein 2b ] (Mus musculus) PubMed

 22037.

miR-103 programs endothelial cells toward a maladapted phenotype through targeting of lncWDR59, which may promote atherosclerosis.[lncWDR59] (Mus musculus) PubMed

 22038.

The active sites of human and staphylococcus glyoxalases I are also different: the former contains one Zn-ion per chain; the latter incorporates two of these ions.. We suggest that only single Zn1-ion plays the role of catalytic center. The newly found differences between the two subfamilies could guide the design of new drugs against S. aureus, an important pathogenic micro-organism. (Mus musculus) PubMed

 22039.

The results suggest that TSST-1 enhances Staphylococcus aureus burden in uterine cavity, the secreted TSST-1 distributes into circulation system, and then systemic inflammation is induced.[TSST-1] (Mus musculus) PubMed

 22040.

Eleven nucleotide polymorphism sites are observed in the human papillomavirus type 45 (HPV45) E6 sequences, with 6 synonymous and 5 non-synonymous mutations. Six nucleotide polymorphism sites are observed in the E7 sequences, with 5 synonymous and 1 non-synonymous mutations. B2 is the most frequent HPV45 sublineage in Southwest China. These mutations reflect positive selection in HPV45 E6 and E7 genes. (Mus musculus) PubMed

 22041.

Data suggest that thermostability of Cel7A in this species (Myceliophthora thermophile M77) is due, in part, to its tadpole-like molecular shape with rigid linker connecting catalytic domain and carbohydrate-binding domain; Cel7A exhibits considerable flexibility. (Cel7A, cellobiohydrolase Cel7A) (Mus musculus) PubMed

 22042.

the exchange protein directly activated by cAMP type 2 (EPAC2) is present in retinal neurons and its specific knockdown using shRNAs abrogates the Dopamine receptor 1-induced ascorbate release.[EPAC2] (Mus musculus) PubMed

 22043.

The disruption of stress granules (SGs) during the late stage of Enterovirus 71 (EV71) infection is caused by viral protease 3C-mediated cleavage of host G3BP stress granule assembly factor 1 (G3BP1). (Mus musculus) PubMed

 22044.

Brassica rapa HAB2a was verified as a putative negative regulator of abscisic acid signaling. The inhibition of HAB2a by abscisic acid and its receptors was successfully recapitulated. [HAB2a] (Mus musculus) PubMed

 22045.

Here, the authors show that the linker regions between the perception and the enzymatic domains shift between distinct states of conformation in an alternating manner in response to signals and that their antagonistic changes control sensor kinase activity. (Mus musculus) PubMed

 22046.

The results show that Cna is a multifunctional protein capable of binding to multiple host ligands through mechanisms that differ from the classical collagen hug. (Can protein) (Mus musculus) PubMed

 22047.

The Listeria monocytogenes virulence factor InlF was found to bind vimentin and was necessary for optimal bacterial colonization of the brain.[InlF] (Mus musculus) PubMed

 22048.

Data suggest that substrate specificity of protein farnesyltransferase (subunits RAM1 plus RAM2) is extensive; these results expand the scope of the potential prenylated proteome in this species. (RAM1, protein farnesyltransferase subunit 1; RAM2, protein farnesyltransferase subunit 2) (Mus musculus) PubMed

 22049.

The authors demonstrate that PfCDPK5 is critical for the discharge of these micronemes and that failure of this step is the molecular mechanism of the parasite egress arrest.[PfCDPK5] (Mus musculus) PubMed

 22050.

the cell wall proteome of a wild-type strain compared to an hwp2 null mutant to determine key differentially expressed proteins, was investigated.[hwp2] (Mus musculus) PubMed

 22051.

These findings highlight the viral role of Epstein-Barr virus-encoded miRNA-BART16 in regulating oncogenic LMP1 expression and a negative association with the proliferation of Epstein-Barr virus-associated gastric carcinoma.[BART16] (Mus musculus) PubMed

 22052.

BZIP48 expression and role in the light regulated development [bZIP48] (Mus musculus) PubMed

 22053.

In summary, the authors propose that TbVps15 has a role in the maintenance of cytokinesis, endocytosis and intracellular trafficking in Trypanosoma brucei.[TbVps15] (Mus musculus) PubMed

 22054.

Pol1 activity of excitatory neurons is required for pentylenetetrazole kindling.[Rna Pol1] (Mus musculus) PubMed

 22055.

uc.40 may play an important role during the differentiation of P19 cells by regulation of PBX1 to promote proliferation and inhibit apoptosis.[Lncrna uc40] (Mus musculus) PubMed

 22056.

the dynamic interactions of KaiA with KaiC on sub-second timescales, are investigated.[kaiA, kaiC] (Mus musculus) PubMed

 22057.

yhcZ gene significantly promotes glucose and other carbon sources utilization during growth. [YhcZ] (Mus musculus) PubMed

 22058.

To overcome this limitation, we developed a CRISPR-Cpf1-based BE by fusing the rat cytosine deaminase APOBEC1 to a catalytically inactive version of Lachnospiraceae bacterium Cpf1. (Mus musculus) PubMed

 22059.

In this study, we present the regulatory mechanism for VvpM expression via repression by at least two transcription factors [VvpM]. (Mus musculus) PubMed

 22060.

These data suggest a functional interplay between INO80's Arp8-Arp4-actin and Arp5 modules in sensing the DNA length separating nucleosomes and regulating nucleosome positioning.[Arp8, Arp4] (Mus musculus) PubMed

 22061.

This study provides evidence that histone modification, DNA methylation and nuclease accessibility coordinated the control of the transcription of TaGS2 homoeologs.[TaGS2A, TaGS2-B, TaGS2-C] (Mus musculus) PubMed

 22062.

early selection of bZIP73(Jap) may have facilitated climate adaptation of primitive rice germplasms.[bZIP73] (Mus musculus) PubMed

 22063.

the crystal structure of a DLP heterotypic pair from the pathogen Campylobacter jejuni, is reported.[DLP1, DLP2] (Mus musculus) PubMed

 22064.

The authors demonstrate that AliC and AliD enhance murine nasopharyngeal colonization and pulmonary infection and are required for otitis media in a chinchilla model.[AliC, AliD] (Mus musculus) PubMed

 22065.

Interruption of UppP's regeneration of C55-P from C55-PP leads to the buildup of cell wall intermediates and cell lysis. [UppP] (Mus musculus) PubMed

 22066.

RpoN regulated flagellar biogenesis and assembly, bacterial mobility, biofilm formation, antibiotic biosynthesis, secretion systems, and carbon utilization. [RpoN] (Mus musculus) PubMed

 22067.

Study characterized a novel hypothetical gene, Ld30b that is specifically transcribed in the intracellular stage of the parasite. It is associated to glycosome and essential for Leishmania growth. [30b] (Mus musculus) PubMed

 22068.

Here we show that FlrA and FlrC, as bEBPs, are partially reciprocal in functionality in this species. As a consequence, the presence of one allows flagellar assembly and motility in the other's absence. (Mus musculus) PubMed

 22069.

Direct electron transfer of nitric oxide reductase (NOR) was described. NOR bioelectrocatalytic activity towards NO and O2 reduction was characterized. Lower Michaelis Menten constant was obtained for NO than for O2. O2 has no significant effect on NOR sensitivity towards NO reduction. [nitric oxide reductase ] (Mus musculus) PubMed

 22070.

EBER2 interaction with host RNA and PAX5.[EBER2] (Mus musculus) PubMed

 22071.

Data suggest that bcl6b functions as factor in immune response in this species; alternative splicing variants of bcl6b appear to function in embryogenesis and in immune response of various tissues. [bcl6b, B-cell lymphoma 6B protein] (Mus musculus) PubMed

 22072.

Mutant phages bearing deletions of orf60a and orf61 impaired two central aspects of phage development.[orf60a and orf61] (Mus musculus) PubMed

 22073.

it could be concluded that LKB1 might be a potential candidate gene affecting the occurrence of rabbit NSDD. This information may serve as a basis for further investigations on rabbit digestive diseases. (Mus musculus) PubMed

 22074.

thioredoxin-like disulfide isomerase; trimerization and active site cysteine required for wild-type swarming activity in the presence of copper [C2LPE2] (Mus musculus) PubMed

 22075.

Proteolysis of histidine kinase VgrS inhibits its autophosphorylation and promotes osmostress resistance in Xanthomonas campestris. [VgrS] (Mus musculus) PubMed

 22076.

The results further highlight that acquisition of the mcr-1 gene may have a very significant clinical impact, contributing to a higher level of colistin resistance. [mcr-1] (Mus musculus) PubMed

 22077.

These data indicate that AprA signaling may be mediated by GrlH in Dictyostelium discoideum.[AprA, GrlH] (Mus musculus) PubMed

 22078.

Together, this work demonstrates that Staphylococcus aureus regulates heme synthesis by modulating GtrR abundance in response to heme deficiency and through the activity of the broadly conserved HemX.[GtrR, HemX] (Mus musculus) PubMed

 22079.

results showed that chi-miR-3031 activated the PI3K-AKT-mTOR pathway and increased beta-casein expression by down-regulating IGFBP5 (chi-miR-3031) (Mus musculus) PubMed

 22080.

[GRA17] NcGRA17 as a dense granule protein determines parasitophorous vacuole morphology and pathogenicity, and alpha-helices of NcGRA17 may be responsible for the aberrant morphology of N. caninum parasitophorous vacuoles. (Mus musculus) PubMed

 22081.

Data provide evidence that BrlR is a binding partner for both c-di-GMP and pyocyanin. As an unusual transcription regulator, BrlR has two separate binding sites with respect to c-di-GMP and pyocyanin. [BrlR] (Mus musculus) PubMed

 22082.

The catalytic mechanism and substrate specificity of a Phenylalanine ammonia-lyase was determined (PAL1). (Mus musculus) PubMed

 22083.

FhbB is a multi-functional protein that may contribute to virulence through several mechanisms including immune evasion, manipulation of the host immune response, adherence or tissue invasion.[Treponema denticola] (Mus musculus) PubMed

 22084.

Data suggest new models of structural basis for free energy differences between ligand-free and ligand-bound conformational states for maltose-binding protein at various concentrations of maltose. (mbp, maltose-binding protein) (Mus musculus) PubMed

 22085.

IL-32gamma functions as intracellular effector in hepatocytes for suppressing hepatitis b virus replication.[IL-32 gamma] (Mus musculus) PubMed

 22086.

Evasion of C3b deposition at division septa and lateral amplification underneath the capsule requires localization of the FH-binding protein PspC at division sites.[PsPc1, PspC2] (Mus musculus) PubMed

 22087.

The gs9 null mutant has slender grains, while overexpression of GS9 results in round grains. [Os09g27590/GS9] (Mus musculus) PubMed

 22088.

OFP19 affects plant architecture and grain shape through modulation of the cell division pattern and brassinosteroid signaling. [OFP19] (Mus musculus) PubMed

 22089.

dynamic allostery can drive cold adaptation in enzymes, such as adenylate kinase from E. coli [adk] (Mus musculus) PubMed

 22090.

Al upregulated MAPK2c and downregulated MAPK1a in both concentration- and time-dependent manners.[MAPK1a, MAPK2c] (Mus musculus) PubMed

 22091.

Study performed a proteomic analysis of Arabidopsis thaliana rolB-expressing callus line AtB-2, which represents a line with moderate expression of the oncogene, rolB from A. rhizogenes; results show that under these conditions rolB greatly perturbs the expression of some chaperone-type proteins such as heat-shock proteins and cyclophilins. (Mus musculus) PubMed

 22092.

These results suggest that Int1 and Sep7 play a role in maintaining genome stability by acting as a diffusion barrier for Lte1.[Int1, Sep7, Lte1] (Mus musculus) PubMed

 22093.

The role of tet(a) and blaKPC-2 in the carbapenem and tigecycline resistance.[tet(a)] [blaKPC-2] (Mus musculus) PubMed

 22094.

Structure-based molecular docking of complex comprised of DNA bound with Gyrase A (large subunit) and Gyrase C (small subunit) with moxifloxacin (MFX) revealed high binding affinity to wild type with considerably high Glide XP docking score of -7.88 kcal/mol (Mus musculus) PubMed

 22095.

Here, the authors investigate the mechanism of Cj0588 action and demonstrate that it is a type I homolog of TlyA that 2'-O-methylates 23S rRNA nucleotide C1920.[TlyA] (Mus musculus) PubMed

 22096.

Catalytic mechanism of type C sialidase from Streptococcus pneumoniae was studied using computational methods. (Mus musculus) PubMed

 22097.

This is the first study on a mitochondrial serine O-acetyltransferase with critical function in sulfur assimilatory metabolism in fungal species.[SAT1] (Mus musculus) PubMed

 22098.

NAD(P)H cytochrome b5 oxidoreductase (Ncb5or) gene is an essential for disease development. [NAD(P)H cytochrome b5 oxidoreductase] (Mus musculus) PubMed

 22099.

Txp40, the recombinant protein characterized from P. luminescens strain H3 exhibited comparatively greater insect toxicity (Galleria mellonella) than strain H1 in terms of LD50 and LT50 values. Photorhabdus luminescens akhurstii, gene Txp40 (Mus musculus) PubMed

 22100.

TaPIMP2 positively contributes to wheat resistance to B. sorokiniana.[TaPIMP2] (Mus musculus) PubMed

 22101.

results suggest that HEIP1 may be a member of the ZMM group and acts as a key element regulating crossover formation[HEIP1] (Mus musculus) PubMed

 22102.

AnCDA activity on crystalline chitin was enhanced by a lytic polysaccharide monooxygenase that increases substrate accessibility by oxidative cleavage of the chitin chains.[AnCDA] (Mus musculus) PubMed

 22103.

Zika virus (ZIKV) protease is a two-component complex in which NS3 contains the catalytic triad and NS2B cofactor region is important for protease folding and activity. Peptides derived from NS2B C-terminus exhibit different binding affinities to Zika virus protease. [protease, NS2B] (Mus musculus) PubMed

 22104.

T6SS dynamics and function depends on the general purpose ClpB unfoldase, which specifically colocalizes with contracted sheaths and is required for their disassembly.[ClpB ] (Mus musculus) PubMed

 22105.

RmtB gene has a a novel insertion sequence element belonging to the ISL3 family.[Rmtb] (Mus musculus) PubMed

 22106.

Transgenic 'W. Murcott' mandarin lines with improved canker resistance via protoplast transformation from embryogenic callus with the Xa21 gene from rice are being evaluated under field conditions to validate the level of resistance. (Mus musculus) PubMed

 22107.

PFE60 influences Maurer's clefts architecture and virulence complex composition.[PFE60] (Mus musculus) PubMed

 22108.

Structural basis for energy transduction has been described by respiratory alternative complex III (quinol:cytochrome c/HiPIP oxidoreductase). [ACIII] (Mus musculus) PubMed

 22109.

Uropathogenic Escherichia coli attach to tissues using pili type 1, each pilus of which is composed by thousands of coiled FimA domains followed by the domains of the tip fibrillum, FimF-FimG-FimH. [FimA], [FimF], [FimG], [FimH] (Mus musculus) PubMed

 22110.

The solute carrier SLC9C1 is a Na(+)/H(+)-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding. [SLC9C1] (Mus musculus) PubMed

 22111.

CD200R in the rat is mainly expressed on myeloid cells but also on non-myeloid cell subsets, and rat cytomegalovirus e127 can deliver inhibitory signals to immune cells by engaging CD200R.[e127] (Mus musculus) PubMed

 22112.

Using transcriptomics and further experiments, study show that Pseudomonas aeruginosa SrpA, directly or indirectly, regulates many cellular processes including cell motility, chemotaxis, biofilm formation, pyocyanin synthesis and protein secretion, as well as virulence in a Caenorhabditis elegans model of infection. (Mus musculus) PubMed

 22113.

miR-UL112-3p exerts its oncogene function by directly targeting TUSC3 in Glioblastoma.[miR-UL112-3] (Mus musculus) PubMed

 22114.

Functional perturbation reveals that Ax6 and Ax1 not only regulate their respective expression domains, but also interact with Wnt genes to pattern the entire oral-aboral axis. [Ax1],[Ax6] (Mus musculus) PubMed

 22115.

The S42 residue of the influenza A virus non-structural protein 1 of the A/swine/Shanghai/3/2014(H1N1) strain is the key amino acid in regulating the host interferon response by blocking the activation of Interferon Regulatory Factor-3 and thus facilitates virus replication. (Mus musculus) PubMed

 22116.

Amino acid substitution in the RNA-binding domain (RBD) of nonstructural protein 1 (NS1) of avian H7N1 influenza virus reduces the pathogenicity and replication potential of influenza A viruses. The impaired virus replication is associated with a delayed synthesis of nucleoprotein NP and a reduced accumulation of NS1. (Mus musculus) PubMed

 22117.

Thus, in addition to its actin-nucleating activities, the Chlamydia pneumoniae CPn0572 also stabilizes preformed host actin filaments.[CPn0572] (Mus musculus) PubMed

 22118.

The expression, purification and crystallographic studies of TssA, a core subunit of the type VI secretion system, has been reported. [TssA] (Mus musculus) PubMed

 22119.

Crystallization and X-ray crystallographic analysis of the mosquito-larvicidal binary toxin receptor protein, Cqm1, has been reported. [Cqm1] (Mus musculus) PubMed

 22120.

CaVIL1 is a major regulator of flowering and interacts with other flowering promoters and repressors, as well as with FLC-LIKE genes whose function in flowering regulation is not yet known in pepper. [CaVIL1] (Mus musculus) PubMed

 22121.

This study identified a multitude of MyoD-mediated lncRNAs for further investigation and identified a novel lncRNA, lnc-AK143003, which plays a role in controlling muscle differentiation. (Mus musculus) PubMed

 22122.

Tp0751 can function as a vascular adhesin.[Tp0751] (Mus musculus) PubMed

 22123.

14-3-3beta protein activates Pseudomonas exotoxin-S and exotoxin-T ADP-ribosyltransferase domains by chaperoning their hydrophobic surfaces independently of the amphipathic C-terminal segment.[exotoxin-S] [exotoxin-T] (Mus musculus) PubMed

 22124.

The results presented here show that in P. fluorescens, AmrZ determines cyclic-di-GMP levels.[AmrZ] (Mus musculus) PubMed

 22125.

A novel recessive gene, xa44(t), confers resistance to bacterial blight in rice [xa44(t)] (Mus musculus) PubMed

 22126.

Results found that PH1 binds to intracellular membranes independently of phosphatidylinositol 3,5-bisphosphate and serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells. [PH1] (Mus musculus) PubMed

 22127.

BnA10.LMI1 positively regulates the development of leaf lobes in B. napus, with cis-regulatory divergences causing the different allelic effects [LMI1] (Mus musculus) PubMed

 22128.

Stb19 is a new resistance gene to Zymoseptoria tritici in wheat [Stb19] (Mus musculus) PubMed

 22129.

Dis3 degrades mRNA but targets predominantly antisense RNA.[Dis3] (Mus musculus) PubMed

 22130.

this study shows that this mutation, which occurs in a regulator-encoding gene, rocA, leads to altered virulence factor expression and reduces the ability of this isolate to survive in human blood. [rocA] (Mus musculus) PubMed

 22131.

These results indicate that HCF-1 encoded by AcMNPV is an essential viral factor for productive NPV infection of Tn368 cells. (Mus musculus) PubMed

 22132.

Pm223899 is a new recessive powdery mildew resistance gene identified in Afghanistan landrace wheat [Pm223899] (Mus musculus) PubMed

 22133.

These results indicate the importance of efaA and acidic conditions in biofilm production by E. faecalis.[EfaA] (Mus musculus) PubMed

 22134.

SNFL1 is an important regulator of leaf development. [SNFL1] (Mus musculus) PubMed

 22135.

Data suggest that beta-N-acetylhexosaminidase in this species forms dimer with pro-peptide from one subunit forming extensive noncovalent interactions with catalytic core of second subunit; this chain swap suggests distinctive structural mechanism of enzyme activation. (HexB, beta-N-acetylhexosaminidase) (Mus musculus) PubMed

 22136.

Data suggest that Csy1-Csy2 heterodimer functions in type I-F CRISPR-Cas system in this species; during formation of crRNA-guided surveillance complex, Csy1-Csy2 heterodimer formation plays critical role. (Csy1 = CRISPR-associated protein-Csy1; Csy2 = CRISPR-associated protein-Csy2) (Csy1, type I-F CRISPR-associated protein-Csy1; Csy2, type I-F CRISPR-associated protein-Csy2) (Mus musculus) PubMed

 22137.

Data suggest Bam complex largely overcomes effects bilayer lipids exert on assembly/folding of outer membrane proteins; Bam complex is composed of BamA (with 5 periplasmic domains) plus four lipoproteins (BamB-E). Studies were conducted using proteins from E. coli strain MC4100. (BamA, beta-barrel assembly machinery subunit-A; BamB, beta-barrel assembly machinery subunit-B; BamC, beta-barrel assembly machinery subunit-C) (Mus musculus) PubMed

 22138.

Our results show that TfoY is induced by c-di-GMP at both low and high intracellular concentrations of c-di-GMP via posttranscriptional and transcriptional mechanisms, respectively [TfoY]. (Mus musculus) PubMed

 22139.

Biophysical investigations demonstrate that a Tarp726-825 construct behaves as a typical intrinsically disordered protein.[Tarp] (Mus musculus) PubMed

 22140.

Here, we show that the C-terminal region of SwrA is important for both transcriptional activation and regulatory proteolysis [SwrA]. (Mus musculus) PubMed

 22141.

BtuM binds vitamin B12 in its base-off conformation, with a cysteine residue as axial ligand of the corrin cobalt ion.[BtuM] (Mus musculus) PubMed

 22142.

The global distribution and spread of the colistin resistance gene mcr-1 has been reported. [mcr-1] (Mus musculus) PubMed

 22143.

POP2 inhibits inflammasome priming and activation [PYDC2] (Mus musculus) PubMed

 22144.

a role for the histone Htz1, which is deposited by the Swr1 chromatin-remodeling complex (SWR-C), in preventing genome instability, is reported.[Swr1] (Mus musculus) PubMed

 22145.

Data suggest that NatB-mediated N-terminal acetylation of Nma1 and Nma2 appears essential for maintaining NAD(+) levels; NatB is complex of subunits Nat3 and Mdm20. These studies were conducted in yeast strain BY4742. (Nma, nicotinamide-nucleotide adenylyltransferase; Nat3, peptide alpha-N-acetyltransferase complex B subunit Nat3; Mdm20, peptide alpha-N-acetyltransferase complex B subunit Mdm20) (Mus musculus) PubMed

 22146.

RamR gene is associated with co-resistance to colistin and tigecycline in a canine Klebsiella pneumoniae ST37.[RamR] MgrB gene is associated with co-resistance to colistin and tigecycline in a canine Klebsiella pneumoniae ST37.[mgrB] (Mus musculus) PubMed

 22147.

Expansion of cross-reactive CD8 T-cell response between influenza virus A-M158 (IAV-M1) and Epstein-Barr virus (EBV) BMLF1280 (EBV-BM) modulates the immune response to EBV and plays a role in determining the severity of Acute Infectious Mononucleosis (AIM). IAV-M1 tetramer(+) cells display increased gamma interferon, a cytokine that amplifies immune responses, thus frequently contributing to induction of immunopathology. (Mus musculus) PubMed

 22148.

Study was conducted to identify the possible effect of recombinant vertebrate ancient long (VAL) opsin as a non-visual "photoreceptor" in the deep brain of goldfish; results, we suggested that VAL-opsin in the deep brain is involved in goldfish maturation, and it is possible that green-wavelength light improves the ability of VAL-opsin to promote maturation by increasing VAL-opsin expression. [VAL-opsin, LOC113112316?] (Mus musculus) PubMed

 22149.

MepA mutation is associated with tigecycline resistance.[MepA] RpsJ mutation is associated with tigecycline resistance.[rpsJ] (Mus musculus) PubMed

 22150.

a conserved role for two basic regions in FAN1 to guide ICL unhooking and to maintain genomic stability. (Mus musculus) PubMed

 22151.

role in the regulation of energy homeostasis and tissue growth via its target genes, contributing to the tolerance of severe hepatic steatosis - [miR29c] (Mus musculus) PubMed

 22152.

EXC-2 binds IFA-4 and controls the excretory canal structure.[EXC-2] (Mus musculus) PubMed

 22153.

Insertion of the blaCTX-M-15 gene into the bacterial genome associated with colistin resistance. [blaCTX-M-15] (Mus musculus) PubMed

 22154.

The alphavarepsilontheta; core of Escherichia coli DNA polymerase III (Pol III) associates with the beta2 sliding clamp to processively synthesize DNA and remove misincorporated nucleotides. (DNA Polymerase III beta2 ). (Mus musculus) PubMed

 22155.

Ama1 activates autophosphorylation of Smk1 on Y209 by promoting formation of the Ssp2/Smk1 complex at prospore membranes.[Ama1, Ssp2, Smk1] (Mus musculus) PubMed

 22156.

LGR1 transcript expression and strong LGR1-like immunoreactivity was also identified in reproductive tissues including the testes and ovaries, which together suggests a potential role linked to spermatogenesis and oogenesis in male and female mosquitoes, respectively.[LGR1] (Mus musculus) PubMed

 22157.

DeltaTM-FlmC belongs to the LytR-CpsA-Psr (LCP) family of domains and is involved in cell envelope biogenesis.[FlmC] (Mus musculus) PubMed

 22158.

Deletion of epe1 (+) impairs downstream events following phosphorylation of Ssp2, including nuclear translocation of Ssp2, sexual differentiation and inhibition of fatty acid synthesis. Our study reveals a novel way in which a jmjC-domain-containing protein regulates adaptive response by directly binding to a principal sensor. (Mus musculus) PubMed

 22159.

ALS1 participates in a defence response resembling the common salicylic acid, jasmonic acid- and NH1-mediated defence responses in rice.[ALS1] (Mus musculus) PubMed

 22160.

Artefactual band patterns by SDS-PAGE of the Vip3Af protein in the presence of proteases mask the extremely high stability of this protein. (Mus musculus) PubMed

 22161.

At micromolar zinc concentrations, oligomeric Zur binding with footprint expansion upward from the Zur box results in high zitB induction.[Zur] (Mus musculus) PubMed

 22162.

Thus the results of the present study provide clear evidence that PfbA can interact with RBCs and this could be one of the important factors in erythrocyte invasion of S. pneumoniae. (Mus musculus) PubMed

 22163.

[Fpy1p] Results suggest that the fpy mutation helps alleviate this phenotype because reduced hydrolysis of FAD and NAD(H) in the mutants lacking Fpy1p in the cytosol helps in two ways: (1) by preserving the FAD needed by the cytosolic NADH-producing dehydrogenases and the G3P shuttle, and (2) by preserving the NADH produced in the cytosol. (Mus musculus) PubMed

 22164.

This work expands the tools available for An. gambiae functional analysis by providing a novel promoter for investigating phenotypes resulting from widespread multi-tissue expression, as well as identifying and tagging genomic sites that sustain broad transcriptional activity. (Mus musculus) PubMed

 22165.

GhSTOP1 is essential for the expression of several genes which are necessary for acid soil tolerance mechanisms and lateral root initiation.[GhSTOP1] (Mus musculus) PubMed

 22166.

Characterization of a novel thiol activated phospholipase TAPLB1 from Trichosporon asahii MSR 54 has been reported. [TAPLB1] (Mus musculus) PubMed

 22167.

cardiac conduction regulatory RNA (CCRR) is identified as an antiarrhythmic long noncoding RNA. (Mus musculus) PubMed

 22168.

L-threonine transaldolase (obaG) is required for L-threo-beta-hydroxy-alpha-amino acid assembly during obafluorin biosynthesis.[ObaG] (Mus musculus) PubMed

 22169.

[HsTRPA] Study identified S. invicta HsTRPA (SiHsTRPA) and characterized its physiological functions; revealed that the amino acids in the N terminus, as well as ankyrin repeat 2 (AR2) of honey bee ortholog AmHsTRPA, are essential for the response to camphor. SiHsTRPA-activating compounds repel red imported fire ants, suggesting that SiHsTRPA functions as a sensor for noxious compounds. (Mus musculus) PubMed

 22170.

These findings suggest that C. jejuni Cas9 is a promiscuous nuclease that can coordinately target both DNA and RNA. (Mus musculus) PubMed

 22171.

The detection of adaptor protein complex 2 mu subunit (pfap2mu) and pfubp1 genotypes associated with ACT delayed parasite clearance is evidence of gradual nascent emergence of resistance in Ghana. The results will serve as baseline data for surveillance and the selection of the genotypes with drug pressure over time [ap2mu]. (Mus musculus) PubMed

 22172.

In this study, we hypothesized that Spherical Body Protein 2 (sbp2) truncated gene members 7, 9 and 11 were attenuation markers for B. bovis. Comparative in silico analysis showed that there are significant size variations and SNPs present in the three sbp2 truncated genes among different geographically divergent B. bovis strains [SBP2]. (Mus musculus) PubMed

 22173.

A beta-agarase was identified from Pseudoalteromonas sp. Q30F and heterologously expressed in Bacillus subtilis WB800n. [beta-agarase] (Mus musculus) PubMed

 22174.

Slx5-Slx8-dependent ubiquitination of Yen1 occurs mainly at K714 and mutation of this lysine increases crossover formation during double-stranded DNA break repair and suppresses chromosome segregation defects in a mus81 background.Slx5, Slx8, Yen1] (Mus musculus) PubMed

 22175.

Data suggest that the bio-catalytic mechanism of QueF involves preQ0 (7-cyano-7-deazaguanine) reduction by L191A and I192A to yield preQ1 (7-aminomethyl-7-deazaguanine) and 7-formyl-7-deazaguanine at 4:1 and 1:1, respectively; these studies were conducted on recombinant QueF in Escherichia coli Escherichia coli BL21-DE3. (QueF, nitrile reductase QueF) (Mus musculus) PubMed

 22176.

Results from anaerobic synchrotron-radiation crystallography (SRX) and aerobic in-house radiation crystallography (iHRX) with a CuNIR (copper-containing nitrite reductase) from the thermophile Geobacillus thermodenitrificans (GtNIR) support the hypothesis that the dioxygen present in an aerobically manipulated crystal can bind to the catalytic type 2 copper (T2Cu) site of GtNIR during SRX experiments. (Mus musculus) PubMed

 22177.

In this study, the authors found that WhiB4 of Mycobacterium marinum, a pathogenic mycobacterial species that is closely related to Mycobacterium tuberculosis, is required for its virulence.[WhiB4] (Mus musculus) PubMed

 22178.

the results indicate that P27 is a novel fibronectin-binding, immunogenic adhesive protein of Mycoplasma bovis, thereby contributing to the further understanding of the molecular pathogenesis of Mycoplasma bovis. [p27] (Mus musculus) PubMed

 22179.

Data suggest that mycolyltransferase/antigen 85C (Ag85C) undergoes post-translational processing/acylation to form covalent complex with tetrahydrolipstatin, an esterase inhibitor that suppresses grown of Mycobacterium tuberculosis and alters structure/conformation of Ag85C. (Ag85C, mycolyltransferase Ag85C) (Mus musculus) PubMed

 22180.

PAS-histidine kinases PHK1 and PHK2 exert oxygen-dependent dual and opposite effects on gametophore formation in the moss Physcomitrella patens. [PHK1],[PHK2] (Mus musculus) PubMed

 22181.

RAD1 transcript levels are up-regulated both in response to AM fungus and, to a lower extent, in infected tissues by Phytophthora palmivora where its expression is restricted to root cortex cells proximal to pathogen hyphae. [RAD1] (Mus musculus) PubMed

 22182.

The data suggest that ClnRAB is a novel regulatory mechanism that senses LL-37 as a host signal and regulates gene expression to adapt to the host intestinal environment during infection. (Mus musculus) PubMed

 22183.

WFSL1 is critical for chloroplast development, ribosome biogenesis, and light energy utilization, finally affects grain yield.[WFSL1] (Mus musculus) PubMed

 22184.

Direct binding of Myb3 to Myb3IPhmw and TvHSP72 was confirmed in vitro. TvCyP1 directly binds to Myb3 and some of its interacting proteins to mediate serial conformational switches of Myb3 for its transition from the membrane compartments toward the nucleus (Myb3, TvCyP1). (Mus musculus) PubMed

 22185.

Fibronectin containing extra domain A (Fn-EDA) induces histological features of plaque instability in established lesions of aged Apoe(-/-) mice. The abundance of Fn-EDA in advanced atherosclerotic lesions may increase the risk of plaque destabilization. (Mus musculus) PubMed

 22186.

Study shows that Dw2, an important dwarfing locus used in grain sorghum breeding, was mapped as a QTL in two Sorghum populations. Using map-based cloning, the gene corresponding to Dw2 was identified as a protein kinase whose closest homolog in Arabidopsis is KIPK, a member of the AGCVIII protein kinase family. [Dw2] (Mus musculus) PubMed

 22187.

the budding yeast Stu2 in complex with the gamma-tubulin receptor Spc72 nucleates microtubules.[Stu2] (Mus musculus) PubMed

 22188.

The authors show that the epimastigote form of the Trypanosoma cruzi knockout for the TcZC3H31 gene (TcZC3H31 KO) is incapable, both in vitro and in vivo (in infected triatomine insects), to differentiate into the metacyclic trypomastigote form, which is responsible for infection transmission from vectors to humans.[TcZC3H31] (Mus musculus) PubMed

 22189.

the underlying membrane geometry is not a deciding factor for FtsZ cluster maintenance and dynamics in vivo.[FtsZ] (Mus musculus) PubMed

 22190.

OsSPX2 was strongly suppressed in OsPIE1 overexpressors.[OsSPX2, OsPIE1] (Mus musculus) PubMed

 22191.

The present study is the first attempt at cloning, structural analysis and functional characterization of two LILRAs (LILRA2 and LILRA6) in chickens. Multiple sequence alignments and construction of a phylogenetic tree of chicken LILRA2 and LILRA6 with mammalian proteins revealed high conservation between chicken LILRA2 and LILRA6 and a close relationship between the chicken and mammalian proteins. [LILRA2, LILRA6] (Mus musculus) PubMed

 22192.

This study identified a novel LysR family transcriptional regulator (LahS) in the A. hydrophila Chinese epidemic strain NJ-35 from a library of 947 mutant strains. [LahS] (Mus musculus) PubMed

 22193.

Disruption of the pocket in RecQ blocks G-quadruplexes (G4) unwinding, but not G4 binding or duplex DNA unwinding, indicating its essential role in structure-specific G4 resolution.[RecQ] (Mus musculus) PubMed

 22194.

DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase, Dbh. [Dbh] (Mus musculus) PubMed

 22195.

GdmRIII, a TetR family transcriptional regulator, controls geldanamycin and elaiophylin biosynthesis in Streptomyces autolyticus CGMCC0516. [GdmRIII] (Mus musculus) PubMed

 22196.

Using proteomics, data showed that SpkG is responsible for the phosphorylation of Fd5 on residues T18 and T72 which seem to modulate protein-protein interaction. Furthermore, Fd5 phosphorylation is affected by the Slr0151 protein encoded by the gene preceding spkG in the gene cluster. Slr0151 functions as an auxiliary protein regulating the ratio between phosphorylated and nonphosphorylated Fd5. [SpkG, Fd5, Slr0151] (Mus musculus) PubMed

 22197.

R. solanacearum uses RipAL to induce jasmonic acid production and suppress salicylic acid signaling in plant cells.[RipAL] (Mus musculus) PubMed

 22198.

Genetic complementation of an Escherichia coli murI mutant demonstrated that Chlamydia DapF can generate d-glutamate.[DapF] (Mus musculus) PubMed

 22199.

ESL4 may function upstream of nitrogen-metabolism genes.[ESL4] (Mus musculus) PubMed

 22200.

The chemokine activity of UNE-N was significantly reduced by suppressing CCR3 expression with CCR3-targeting siRNA, and the loop3 region of UNE-N was shown to interact mainly with the extracellular domains of CCR3 in nuclear magnetic resonance perturbation experiments. Based on these results, evolutionarily acquired UNE-N elicits chemokine activities that would promote NRS-CCR3-mediated proinflammatory signaling in ILD. (Mus musculus) PubMed

 22201.

Here the authors show that a majority of the transcriptomic effects in tachyzoite-infected cells depend on the activity of a novel translocation system involving MYR1 and that the effectors delivered by this system are part of an intricate interplay of activators and suppressors. (Mus musculus) PubMed

 22202.

the Fe deficiency-inducible MYB transcription factor MdMYB58 in apple plants, was characterized.[MdMYB58] (Mus musculus) PubMed

 22203.

CaHsfB2a positively regulates plant immunity against Ralstonia solanacearum Infection and tolerance to High Temperature and High Humidity, via transcriptional cascades and positive feedback loops involving CaWRKY6 and CaWRKY40.[CaHsfB2a, CaWRKY6, CaWRKY40] (Mus musculus) PubMed

 22204.

This study demonstrates enzymatically that LtgA, a non-canonical, substrate-permissive Lytic transglycosylase from Neisseria meningitidis utilizes chitopentaose ((GlcNAc)5) as a substrate to produce three newly identified sugars: 1,6-anhydro-chitobiose, 1,6-anhydro-chitotriose, and 1,6-anhydro-chitotetraose. [LtgA] (Mus musculus) PubMed

 22205.

AraR and XlnR have significantly similar, but not the same, DNA-binding properties. Such a slight difference in these paralogous transcription factors may lead to complex outputs in enzyme production depending on the concentrations of coexisting inducer molecules in the natural environment. (Mus musculus) PubMed

 22206.

ZC3H30 confers a selective advantage in the wild, where the parasites are subject to temperature fluctuations and immune attack in both the insect and mammalian hosts.[ZC3H30] (Mus musculus) PubMed

 22207.

One important bacterial zinc transporter is AdcA. Using molecular simulation and experimental validations of AdcA from Streptococcus pyogenes, the study found that the two AdcA domains sequentially stabilize the structure upon zinc binding, indicating an organization required for both increased zinc affinity and transfer speed. [AdcA ] (Mus musculus) PubMed

 22208.

Using small-angle X-ray and neutron scattering analyses with contrast variation, the study determined a low-resolution structure of the ScsC-ScsB alpha complex. The structural model of this complex suggested that ScsB alpha uses both of its immunoglobulin-like folds to interact with ScsC and revealed that the highly dynamic ScsC becomes ordered upon ScsB alpha binding. [ScsC, ScsB alpha ] (Mus musculus) PubMed

 22209.

Therefore, ComRS control of comX does not require either the import or extracellular accumulation of ComS or XIP or specific processing of ComS to XIP.[ComR, ComS] (Mus musculus) PubMed

 22210.

Altogether, these findings suggest that Fbp1 functions as a novel virulence factor that shapes the immunogenicity of Cryptococcus neoformans.[Fbp1] (Mus musculus) PubMed

 22211.

analysis of the peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumonia [MurT, GatD] (Mus musculus) PubMed

 22212.

These results suggested that similarly to its homologues in plants, TbMCP12 transports both dicarboxylates and tricarboxylates across the mitochondrial inner membrane.[TbMCP12] (Mus musculus) PubMed

 22213.

An atypical carboxylesterase was isolated from Bacillus coagulans (BCE), endowed with high enantioselectivity toward different 1,2-O-isopropylideneglycerol (IPG or solketal) esters. BCE efficiently catalyzes the production of enantiopure (S)-IPG. Crystal structures of BCE in apo- and glycerol-bound forms at resolutions of 1.9 and 1.8 A, respectively, were used to study substrate binding. It has a lipase-like 3D fold. BCE. (Mus musculus) PubMed

 22214.

Mutant cells with UUT1 deleted lack capsule polysaccharides and are highly sensitive to environmental stress. As a result, the deletion mutant is internalized and cleared by phagocytes more readily than wild-type cells are and is completely avirulent in mice.[UUT1] (Mus musculus) PubMed

 22215.

Single nucleotide polymorphism of MAL73 decreased the maltose fermentation ability of sake brewing yeast. (Mus musculus) PubMed

 22216.

we demonstrate for the first time that RNase Y processing of an mRNA target requires the presence of a guanosine . We also provide new insights on the speB 5' UTR and on the role of RNase Y in speB regulation. (Mus musculus) PubMed

 22217.

This study helped elucidate the functions of miR172 in perennial plants, a known age-related miRNA involved in the regulation of perennial plant phase change and organ development.[miR172] (Mus musculus) PubMed

 22218.

At least two proteases induced by heat shock, ClpPA and Lon, were responsible for determining the instability of SmcR. In vitro and in vivo assays demonstrated that SmcR levels were regulated via proteolysis by these proteases, with preferential proteolysis of monomeric SmcR.[SmcR] (Mus musculus) PubMed

 22219.

Engineered intramolecular disulfide bonds in TmYidC, in combination with complementation assays, suggest that significant rearrangement of the 2 alpha-helical bundles at the top of the hydrophilic groove is critical for TmYidC function. These experiments provide a more detailed mechanical insight into YidC-mediated membrane protein biogenesis. (Mus musculus) PubMed

 22220.

These findings demonstrate that, though multiple autophagy-dependent and independent functions have been proposed for PfATG8, only its role in apicoplast biogenesis is essential in blood-stage parasites. We propose that PfATG8 is required for fission or segregation of the apicoplast during parasite replication.[PfATG8] (Mus musculus) PubMed

 22221.

These findings demonstrate that O-mannosylation of proteins via Pmt1 and Pmt2 increases the thermotolerance of Histoplasma yeast cells, which facilitates infection of mammalian hosts.[Pmt1, Pmt2] (Mus musculus) PubMed

 22222.

Mining of aminotransferase gene ota3 from Bacillus pumilus W3 via genome analysis, gene cloning and expressing for compound bioamination. (Mus musculus) PubMed

 22223.

The crystal structure of the DNA-binding domain of CbnR in complex with the recognition-binding site of the cbnA promoter at 2.55 A resolution revealed details of the interactions between the DNA-binding domain and the promoter DNA, including promoter sequence selectivity. (Mus musculus) PubMed

 22224.

The C-terminal region of DRC2 is critical for the coassembly of DRC2 and DRC1 to form the base plate of N-DRC and its attachment to the outer doublet microtubule. Loss of DRC2 disrupts the assembly of several other N-DRC subunits and destabilizes the assembly of several closely associated structures such as the inner dynein arms, the radial spokes, and the calmodulin- and spoke-associated complex. [DRC2] (Mus musculus) PubMed

 22225.

LplT/Aas system is important for maintaining the integrity of the membrane envelope in Gram-negative bacteria [LplT] (Mus musculus) PubMed

 22226.

biochemical analysis of a 6-phosphogluconate dehydrogenase from Synechocystis sp. PCC 6803.[6PGDH] (Mus musculus) PubMed

 22227.

The molecular structure of Blastomyces dermatitidis aspartate semialdehyde dehydrogenase (ASADH) in complexes with cofactors and inhibitors has been resolved. [ASADH] (Mus musculus) PubMed

 22228.

knockdown of microRNA166, using the Short Tandem Target Mimic (STTM) system, resulted in morphological changes that confer drought resistance in rice.[miRNA166] (Mus musculus) PubMed

 22229.

Data suggest that Chi18D and LPMO10A are important in degradation of chitin in this species; Chi18D is highly expressed during chitin utilization. (Chi18D = glycoside hydrolase/chitinase Chi18D; LPMO10A = lytic polysaccharide monooxygenase LPMO10A) (Mus musculus) PubMed

 22230.

ROC75 acts as an attenuator of the circadian clock to control LHCSR3 expression with blue and red light as stimuli for attenuation.[ROC75, LHCSR3] (Mus musculus) PubMed

 22231.

MinC and FtsZ mutant analysis suggests that inhibition of the Z ring by MinC alone is due to sequestration, whereas inhibition by MinC/MinD is not. In conclusion, the genetic and biochemical data support the model that MinC/MinD fragments FtsZ filaments. [MinC, FtsZ, MinD] (Mus musculus) PubMed

 22232.

ZmGa1P protein is predominantly localized to the apex of growing pollen tubes and may interact with another pollen-specific PME protein, ZmPME10-1, to maintain the state of pectin methylesterification required for pollen tube growth in Ga1-S silks [ZmGa1P, ZmPME10-1] (Mus musculus) PubMed

 22233.

Report have shown that OhrR is induced by intracellular organic hydroperoxide stress and demonstrated the ability of OhrR to sense intracellular organic hydroperoxides. [OhrR] (Mus musculus) PubMed

 22234.

these results indicated that phosphorylation by FgPrp4 at multiple sites may release the self-inhibitory binding of FgPrp31 and affect its interaction with other components of tri-snRNP during spliceosome activation. (Mus musculus) PubMed

 22235.

The fumarate hydratase gene could not be knocked out in Plasmodium berghei when transfectants were introduced into BALB/c mice; however, fumarate hydratase knockout was successful when C57BL/6 mice were used as host, suggesting that the essentiality of the fumarate hydratase gene to the parasite was mouse strain-dependent. [fumarate hydratase] (Mus musculus) PubMed

 22236.

This study reports on the kinetic characterization of purified recombinant fumarate hydratase, functional complementation of fumarate hydratase deficiency in Escherichia coli, and mitochondrial localization in the parasite. The substrate analog mercaptosuccinic acid is a potent fumarate hydratase inhibitor, with a Ki value in the nanomolar range. [fumarate hydratase] (Mus musculus) PubMed

 22237.

Structural rearrangement of the C-terminal residues upon ligand binding was crucial for SseK3's catalytic activity, and NMR analysis indicated that SseK3 has limited UDP-GlcNAc hydrolysis activity. The release of free N-acetyl alpha-d-glucosamine, and the presence of the same molecule in the SseK3 active site, classified it as a retaining glycosyltransferase. [SseK3] (Mus musculus) PubMed

 22238.

valuable details to forestall RMP resistance [RpoB] (Mus musculus) PubMed

 22239.

Upregulation of lncRNA CASC15 induced by VDR transcription factor facilitates cardiac hypertrophy via miR-432-5p/TLR4 axis. [lncRNA CASC15] (Mus musculus) PubMed

 22240.

Disruption of an oligomeric interface prevents allosteric inhibition of Escherichia coli class Ia ribonucleotide reductase [class Ia ribonucleotide reductase] (Mus musculus) PubMed

 22241.

we demonstrate the existence of a new c-type lysozyme inhibitor in Neisseria. We named the protein SliC as a surface-exposed lysozyme inhibitor of c-type lysozyme (Mus musculus) PubMed

 22242.

we have elucidated the biological features and function of uc.4, which was expressed in abnormal embryonic heart tissues, and detailed its possible roles in embryonic heart development. (Mus musculus) PubMed

 22243.

Study shows that in Bacillus subtilis stabilization of Spx requires a novel anti-adaptor protein, YirB, which prevents Spx degradation by binding to and inhibiting the activity of the adaptor protein YjbH (YirB). (Mus musculus) PubMed

 22244.

Puf5 functions in the cell wall integrity pathway by regulating LRG1 expression in a deadenylase-independent manner.[Puf5, LRG1] (Mus musculus) PubMed

 22245.

Compared with the control sample, the NS3 protein significantly increased the expression level of IL-24 and its related receptors, IL-20R and IL-22R [NS3]. (Mus musculus) PubMed

 22246.

Study describes the identification of the Triticum turgidum ssp. Dicoccoides Yr15 gene sequence by map-based cloning and demonstrate its function in conferring resistance to yellow rust in durum and common wheats. Yr15 encodes a protein composed of putative kinase and pseudokinase domains in tandem, which was named as WTK1 (wheat tandem kinase 1). (Mus musculus) PubMed

 22247.

characterization of a histidinol phosphate phosphatase from Mycobacterium tuberculosis [histidinol phosphate phosphatase] (Mus musculus) PubMed

 22248.

A novel motif unique to PfDJ1 and several other hDJ1-like proteins, with the consensus sequence of TSXGPX5FXLX5L, was identified that we designated as the hDJ1-subfamily motif and it is critical for anti-oxidative and deglycase activities. [DJ1] (Mus musculus) PubMed

 22249.

Crystal structure confirms that BstA belongs to the YfiT-like metal-dependent hydrolase superfamily and contains nickel within its active site. [BstA] (Mus musculus) PubMed

 22250.

Isolation and functional characterization = [FLOWERING LOCUS T homolog (NtFT5)] (Mus musculus) PubMed

 22251.

Gpd1 in K. lactis is essential for growth on ethanol (Gpd1) (Mus musculus) PubMed

 22252.

TaZnF acts as a positive regulator of thermal stress.[TaZnF] (Mus musculus) PubMed

 22253.

a glycosylphosphatidylinositol-anchored lipid transfer protein necessary for pollen development - [Ms1] (Mus musculus) PubMed

 22254.

Results show that MbTrxC-AhpC forms an NADPH-dependent peroxidase ensemble for efficient reduction of H2O2 inside the mycobacterial antioxidant defense system and identify the amino acids involved in TrxC and AhpC interaction. AhpC undergoes a redox-modulated dimer to dodecamer formation, in which the unique mycobacterial N-terminal stretch of AhpC place a fundamental role. [AhpC, TrxC] (Mus musculus) PubMed

 22255.

Results show that di-lysine ER retention motif of AnkB-Paris is indispensable for function; most likely as an ER retention motif that enables anchoring to the ER-derived Legionella-containing vacuole (LCV) membrane. The findings show divergent evolution of the ankB allele in exploiting either host farnesylation or the ER retention motif to be anchored into the LCV membrane. [AnkB] (Mus musculus) PubMed

 22256.

role in the regulation of plant structure through the control of different phytohormones and altered cell structure - [SDSFL1] (Mus musculus) PubMed

 22257.

ectopic expression in Arabidopsis enhances drought tolerance - [RHD3] (Mus musculus) PubMed

 22258.

Crystal structure of the PGRP-SA protein shows peptidoglycan binding site.[PGRP-SA] (Mus musculus) PubMed

 22259.

the present study identified that Erbb4-IR is a novel lncRNA responsible for TGF-beta/Smad3-mediated renal fibrosis by downregulating Smad7. Targeting Erbb4-IR may represent a precise therapeutic strategy for progressive renal fibrosis. (Mus musculus) PubMed

 22260.

Compared to BCPI, BmCPI exhibited weak inhibitory activity toward cathepsin L. BCPI activity was significantly decreased when its C-terminus was truncated, whereas BmCPI activity increased considerably when the C-terminus tail of BCPI was attached to BmCPI. [BmCPI] (Mus musculus) PubMed

 22261.

Rab-7A RAB-2 Rab GTPases are involved in the regulation of mycelial growth, conidiation, trap formation, stress resistance, and pathogenicity in the nematode-trapping fungus A. oligospora. (Mus musculus) PubMed

 22262.

XopL suppresses stromules and induces plastid clustering.[Xopl] (Mus musculus) PubMed

 22263.

Study results support a model in which B. subtilis GlmR facilitates the diversion of carbon from the central metabolite fructose-6-phosphate, which is limiting in cells growing on gluconeogenic carbon sources, into peptidoglycan biosynthesis by stimulating GlmS activity, and propose that binding of UDP-GlcNAc may attenuate this stimulation (GlmR (formerly YvcK). (Mus musculus) PubMed

 22264.

The cel-EIIB protein-mediated cel-phosphotransferase system not only contributes to biofilm formation and virulence regulation, but also plays an important role in the invasion and colonization of S. agalactiae in Nile tilapia.[cel-EIIB protein] (Mus musculus) PubMed

 22265.

A knock-out mutant of the PBANKA_1003900 gene was not affected in sexual development and ookinete formation was similar to WT. The mutation had no adverse effect on transmission through the mosquito although there was a reduction of the number of oocysts formed by the mutant parasites.[PBANKA_1003900] (Mus musculus) PubMed

 22266.

Natronomonas pharaonis halorhodopsin mechanism of stabilization of the binding state between a chloride ion and Thr126at binding site-1 (Mus musculus) PubMed

 22267.

male sex-differentiation factor Dmrt1 positively regulates the transcription of the Nile tilapia Sox9b gene by directly binding to a specific cis-regulatory element within the Sox9b promoter[sox9b] (Mus musculus) PubMed

 22268.

By comparing the expression profile of deltamethrin-resistant and -susceptible wild mosquitoes from China, we identified 3 candidate genes one of which is CYP6A8 with increased expression in resistant Ae. albopictus [CYP6A8]. (Mus musculus) PubMed

 22269.

determines the inflorescence architecture by controlling brassinosteroid biosynthesis - [PMM1] (Mus musculus) PubMed

 22270.

Gene silencing study of a novel protein kinase named as EiCSpk (Entamoeba invadenscyst specific protein kinase) has unveiled its role as a regulator of chitin synthesis through transcriptional activation of the chitin synthesis pathway genes along with glycogen phosphorylases that are involved in the influx of glucose from glycogen breakdown for chitin synthesis.[EiCSpk] (Mus musculus) PubMed

 22271.

Here the authors demonstrate in Xanthomonas citri that host-induced phosphorylation of the ATP-dependent protease Lon stabilizes HrpG, the master regulator of type III secretion systems, conferring bacterial virulence.[Lon, HrpG] (Mus musculus) PubMed

 22272.

Authors show that CARDS toxin translocates through early and late endosomes and the Golgi complex and concentrates at the perinuclear region to reach the endoplasmic reticulum (ER).[CARDS] (Mus musculus) PubMed

 22273.

Deletion analysis of ATG16 showed that the N-terminal half of ATG16 interacted directly only with PSMD1, while the C-terminal half interacted with both, PSMD1 and PSMD2.[ATG16, PSMD1, PSMD2] (Mus musculus) PubMed

 22274.

Kex2p-mediated proteolysis of Ece1p after Arg61 and Arg93, but not after other processing sites within Ece1p, is required to generate immature candidalysin from Ece1p, followed by Kex1p-mediated removal of a carboxyl arginine residue to generate mature candidalysin.[Ece1, Kex2, Kex1] (Mus musculus) PubMed

 22275.

Study in Paenibacillus polymyxa reveal that during nitrogen limitation, GlnR binds to GlnR-binding site I located upstream of -35/-10 regions of nif promoter of nif operon (nifBHDKENXhesAnifV) in a weak and transient association way and then activates nif transcription. (Mus musculus) PubMed

 22276.

Transport of hypoxanthine in bloodstream forms grown axenically in HMI-9 medium was mainly performed by a previously not described hypoxanthine-specific transporter (HXT1) with a Km of 22+/-1.7muM(10(7)cells)(-1)s(-1). The uptake of adenine was also assessed in the knockout cells and was performed by a highly specific adenine transporter (ADET1) with a Km of 573+/-62nM(10(7)cells)(-1)s(-1).[HXT1, ADET1] (Mus musculus) PubMed

 22277.

SseK1 crystal structure is composed of a helix-loop-helix domain, a lid domain, and a catalytic domain. A conserved HEN motif (His-Glu-Asn) in the active site is important for enzyme catalysis and bacterial virulence.[SseK1][SseK2] (Mus musculus) PubMed

 22278.

TaVAP plays a critical role in growth and development in plants, and is a potential candidate for improving the abiotic stress tolerance in crop plants.[TaVAP] (Mus musculus) PubMed

 22279.

tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase from Acinetobacter baumannii [UDP-GlcNAc-2-epimerase] (Mus musculus) PubMed

 22280.

CIF3 cooperates with the CIF1 protein to promote cytokinesis in Trypanosoma brucei [CIF3][CIF1] (Mus musculus) PubMed

 22281.

RgsP and RgsM contribute to the regulation of unipolar cell wall biogenesis in alpha-rhizobia. [RgsP and RgsM] (Mus musculus) PubMed

 22282.

HEN1 mediated methylation of sRNAs reflects the ancestral state, where miRNAs were also methylated. [HEN1] (Mus musculus) PubMed

 22283.

These results suggest that EscV serves as a binding platform for both the SepL regulatory protein and secreted substrates during the ordered assembly of the type three secretion system.[SepL, EscV] (Mus musculus) PubMed

 22284.

Upon exposing L. donovani promastigotes to amastigote differentiation signal, parasites rapidly and completely degrade LdAAP24 protein in both axenic and in spleen-derived amastigotes. [ LdAAP24] (Mus musculus) PubMed

 22285.

Crystal stuctures of MglB-2 reveals glucose-induced conformational changes.[MglB-2] (Mus musculus) PubMed

 22286.

In this report, the authors have biochemically characterized metacaspase-2 (PfMCA-2) of Plasmodium falciparum. Enzymatic assay showed that PfMCA-2 efficiently cleaved arginine/lysine specific peptide, but not caspase-specific substrate.[PfMCA-2] (Mus musculus) PubMed

 22287.

ARN6.1 has an important role in increasing cucumber adventitious root formation and waterlogging tolerance. [ARN6.1] (Mus musculus) PubMed

 22288.

lncKBTBD10 could induce a decrease of KBTBD10 protein and further to affect bovine skeletal muscle myogenesis.[lncKBTBD10] (Mus musculus) PubMed

 22289.

For cl1 sesame mutant, curling leaf and indehiscent capsule traits are controlled by a same recessive gene (Sicl1) (Mus musculus) PubMed

 22290.

beta-ketoacyl-acyl carrier protein reductase MabA The crystal structure of the apo form revealed numerous residues that trigger steric hindrance to the binding of NADPH and substrate. Upon NADPH binding, these residues are pushed away from the active site, allowing the enzyme to adopt an open conformation. (Mus musculus) PubMed

 22291.

Npa1p and Dbp6p function in the formation and/or clustering of root helices of large subunit rRNAs which creates the core of the large ribosomal subunit RNA structure. Npa1p also crosslinks to snoRNAs involved in decoding center and peptidyl transferase center modifications and in the immediate vicinity of the binding sites of these snoRNAs on 25S rRNA. [Npa1p] (Mus musculus) PubMed

 22292.

At 4 h postinfection with Escherichia coli, RNAi-based knockdown of draper results in a marginal increase in the number of periostial haemocytes and a doubling of E. coli accumulation at the periostial regions. At 24 h postinfection, knockdown of eater decreases the number of periostial haemocytes and decreases the phagocytosis of E. coli on the surface of the heart.[eater, draper] (Mus musculus) PubMed

 22293.

The fungal VosA-SclB regulatory system of transcription includes a VosA control of the sclB promoter, common and opposite VosA and SclB control functions of fungal development and several additional regulatory genes. SclB is a repression target of VosA and both transcription factors are part of a mutual control in the timely adjusted choreography of asexual sporulation in A. nidulans (VosA and SclB). (Mus musculus) PubMed

 22294.

Study concludes that FgAtg9 is essential for autophagy-dependent development and pathogenicity of F. graminearum, which may be regulated by the small GTPase FgRab7. (Mus musculus) PubMed

 22295.

Study results suggest that the proper level of CBF-1 is critical for circadian clock function in Neurospora crassa by suppressing WHITE COLLAR (WC)-independent FRQ expression and by regulating WC complex binding to the frq promoter. (Mus musculus) PubMed

 22296.

Study show that miR-202-5p is the most abundant mature form of the mir-202 miRNA in Oryzias latipes and that it is expressed in granulosa cells and in the unfertilized egg. The knock out of mir-202 gene resulted in a strong phenotype both in terms of number and quality of eggs produced. (Mus musculus) PubMed

 22297.

impaired turnover of the misfolded substrate was caused by frequent background mutations in the general stress response gene WHI2.[WHI2] (Mus musculus) PubMed

 22298.

A detailed deletion analysis of the pRet42e (505 kb) plasmid from an Rhizobium etli mutant with enhanced CuCl2 tolerance led to the identification of the ropAe gene, predicted to encode an outer membrane protein (OMP) with a beta-barrel channel structure that may be involved in copper transport.[RopAe] (Mus musculus) PubMed

 22299.

Functions of two luxS genes, heterologous expression and protein purification were performed, and activity on AI-2 synthesized in vitro using a reporter strain Vibrio harveyi BB170 bioassay was determined. Finally, the effects of temperature, various metal ions and chemical reagents on enzyme activities, and the enzyme kinetic parameters were assessed. (genes: luxS1 & luxS2) (Mus musculus) PubMed

 22300.

we show for the first time the phosphorylation of HSP27 by a bacterial effector-P. gingivalis-Ndk-and a novel function of Ndks that is directly involved in inhibition of host cell apoptosis and the subsequent bacterial survival. (Mus musculus) PubMed

 22301.

This study indicated the capability of coexpression of sHSP20 to increase the efficiency of prokaryotic expression of fungal genes and the activity of expressed enzymes.[sHSP20] (Mus musculus) PubMed

 22302.

structure of SALM5 suggests a dimeric assembly for the presynaptic RPTP ligand recognition (Mus musculus) PubMed

 22303.

Mass spectrometry analysis revealed a similar substrate cleavage pattern between the bacterial and human Lon variants, which was exemplified by predominant representation of leucine, alanine, and other hydrophobic amino acids at the P(-1) site within the substrates. [Lon] (Mus musculus) PubMed

 22304.

These results account for the Ded1 hyper-dependence of mRNAs with structure-prone 5'-UTRs, and implicate an eIF4E.eIF4G.eIF4A.Ded1 complex in accelerating 48S preinitiation complex assembly on native mRNAs.[Ded1, eIF4F] (Mus musculus) PubMed

 22305.

83 in vivo interactors of the sole small heat-shock proteins in the cyanobacterium Synechocystis sp. PCC 6803, HSP16.6, reflective of stable associations with soluble proteins made under heat-shock conditions, were identified.[HSP16.6] (Mus musculus) PubMed

 22306.

In the 3' UTR of maize necrotic streak virus (MNeSV), an I-shaped RNA structure (ISS) has been shown to bind eukaryotic initiation factor (eIF)4F and to mediate viral translation initiation. [eIF4F] (Mus musculus) PubMed

 22307.

molecular characterization and expression analysis upon immune stimulation by bacteria - [PGRP6] (Mus musculus) PubMed

 22308.

role in response to inflammatory stimulation in immune cells -[casepase 3 and caspase 8] (Mus musculus) PubMed

 22309.

Hsp31p-GFP fusion protein is localized to the cytosol under most environmental conditions and that it becomes particulate in response to oxidative stress.[Hsp31, glyoxalase III] (Mus musculus) PubMed

 22310.

MIF enhances survival under adverse conditions and defined TvMIF and huMIF as conserved survival factors that exhibit cross talk in host-pathogen interactions. (Mus musculus) PubMed

 22311.

RARP-2 is secreted by a type IV secretion system into the cytosol of the host cell, where it interacts with and manipulates the structure of the endoplasmic reticulum.[RARP-2 ] (Mus musculus) PubMed

 22312.

Analysis of PopD's interaction with human cell membranes revealed that PopD adopts a distinctive conformation when PopB is present. An N-terminal region of PopD is only exposed to the host cytosol when PopB is present. [PopD, PopB] (Mus musculus) PubMed

 22313.

Nrf2-mediated signaling affects embryo survival, midgut homeostasis, and redox biology in Aedes aegypti, a mosquito species vector of dengue, Zika, and other disease-causing viruses. Nrf2 silencing increases Reactive Oxygen Species levels and stimulates intestinal stem cell proliferation. [Nrf2] (Mus musculus) PubMed

 22314.

data renewed the understanding of the relationship between S. aureus golden pigment and its virulence and suggested that a single substitution mutation in SigB might enhance the biofilm formation of S. aureus by directly downregulating nuc expression [SigB]. (Mus musculus) PubMed

 22315.

salt-inducible expression improves resilience against salt-stress - [JAZ8] (Mus musculus) PubMed

 22316.

Collectively, these findings indicate that Porphyromonas gingivalis InlJ and Candida albicans Als3-dependent binding facilitates interdomain community development between the two species and that Porphyromonas gingivalis has the potential for increased virulence within such communities.[InlJ] (Mus musculus) PubMed

 22317.

role in regulating chloroplast avoidance - [PHOT2] (Mus musculus) PubMed

 22318.

data suggest that Six5 contributes to the virulence of Fusarium by facilitating Avr2 movement via plasmodesmata (Six5 and Avr2) (Mus musculus) PubMed

 22319.

The presence of naturally acquired antibodies to Rhoptry Neck Protein 2 (RON2) in the absence of the disease suggests that RON2 induces a long-term antibody response (RON2). (Mus musculus) PubMed

 22320.

ES-P elevates collagen I via activation of the TGF-beta1 signaling pathway in vitro and in vivo. [ES-P] (Mus musculus) PubMed

 22321.

acts as a negative regulator of OsMYC2-mediated jasmonic acid signaling - [NINJA1] (Mus musculus) PubMed

 22322.

involved, along with its potential target gene RPL18, in the adaptation to UV-B - [Cre-miR914] (Mus musculus) PubMed

 22323.

photoperiod response contributes to flowering - [COL1] (Mus musculus) PubMed

 22324.

positively regulates disease resistance to Magnaporthe oryzae - [ERF83] (Mus musculus) PubMed

 22325.

GA2oxA9 expression and its role in wheat growth. [GA2oxA9] Rht18 expression and its role in wheat growth and gibberellins metabolism.[Rht18] (Mus musculus) PubMed

 22326.

the expression of miR-26 is directly related to milk fatty acid composition and underscores the significance of miRNAs in milk fat synthesis regulation [miR-26] (Mus musculus) PubMed

 22327.

this study presents a structural and functional characterization of Bab2_0215, which wasnamed B rucella adipic acid-activated regulator (BaaR). [BaaR] (Mus musculus) PubMed

 22328.

study reveals the important role of OsSK41 in rice grain development and provides new candidate genes for genetic improvement of grain yield in rice (OsSK41) (Mus musculus) PubMed

 22329.

a major QTL, qTGW3, encodes a negative regulator of grain length and weight and coordinately alters cell size and cell number in the spikelet hull. (qTGW3) (Mus musculus) PubMed

 22330.

Loss of ybeY in Enterohemorrhagic Escherichia coli had pleiotropic effects on the cells, including reduced motility and growth and cold sensitivity. [ybeY] (Mus musculus) PubMed

 22331.

The crystal structures of Sop n -binding protein (SO-BP, Lin1841) in an unliganded open form and in closed complexes with tri-, tetra-, and pentaoligosaccharides (Sop3-5) were determined to a maximum resolution of 1.6 A. [Sop n -binding protein] (Mus musculus) PubMed

 22332.

Deletion of the hdaA gene induces a significant pleiotropic effect on the expression of a set of polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS)-encoding genes.[hdaA] (Mus musculus) PubMed

 22333.

these findings highlight the role of the polyubiquitin gene UBI4 in apoptosis and implicate UBI4 as a modulator of the replicative lifespan.[UBl4] (Mus musculus) PubMed

 22334.

The role of OleA His285 in orchestration of long-chain acyl-coenzyme A substrates. (Mus musculus) PubMed

 22335.

A transient induction of the human UNC45-GC, but not UNC45-SM, could rescue the defective endocytosis in these she4Delta cells at 39 degrees C, irrespective of whether they possessed Hsp90alpha or Hsp90beta.[She4] (Mus musculus) PubMed

 22336.

Mot1 adopts a ring like structure with a catalytically inactive resting state of the ATPase.[Mot1] (Mus musculus) PubMed

 22337.

determination of the structures of the pore-forming mitochondrial calcium uniporter(MCU) proteins from two fungi by X-ray crystallography and single-particle cryo-electron microscopy [MCU] (Mus musculus) PubMed

 22338.

determination of the structures of the pore-forming mitochondrial calcium uniporter(MCU) proteins from two fungi by X-ray crystallography and single-particle cryo-electron microscopy [MCU] (Mus musculus) PubMed

 22339.

cryo-electron microscopy reconstructions of MCU channels from zebrafish and Cyphellophora europaea at 8.5 A and 3.2 A resolutions, respectively [MCU] (Mus musculus) PubMed

 22340.

electromagnetic field exposure could elevate the de novo generation and propagation of yeast prions.[URE3] (Mus musculus) PubMed

 22341.

Study presents evidence that EapH1 and EapH2 bind to Neutrophil Elastase (NE), in distinct orientations. The alteration of EapH1 residues at the EapH1/NE interface caused a dramatic loss of affinity and inhibition of NE, while mutation of equivalent positions in EapH2 had no effect on NE. Also, mutation in different region of EapH2 severely impacted both the NE binding and inhibitory effect of EapH2. [EapH1 and EapH2] (Mus musculus) PubMed

 22342.

In P. aeruginosa, PppA and TagF are two distinct proteins that repress T6SS in TPP-dependent and -independent pathways, respectively. P. aeruginosa TagF interacts with Fha1, suggesting that formation of this complex represents a conserved TagF-mediated regulatory mechanism. [TagF, Fha1] (Mus musculus) PubMed

 22343.

TagF inhibits The bacterial type VI secretion system (T6SS)without affecting T6SS protein abundance. This repression requires interaction with a cytoplasmic protein, Fha, critical for activating T6SS assembly. [Fha, TagF] (Mus musculus) PubMed

 22344.

AmiC positively regulates the acetamidase operon.[AmiC] (Mus musculus) PubMed

 22345.

this is the first report demonstrating the presence of a caa3 -Cox using cyt c4 as an electron donor in a Pseudomonas species. (Mus musculus) PubMed

 22346.

Inverse correlation observed in this study between promoter methylation and gene expression of Bovine vasa homology (Bvh) gene in spermatozoa from crossbred bulls with poor motility phenotype as compared to purebred parents provides an important insight into understanding the graded fertility of crossbred bulls.[Bvh] (Mus musculus) PubMed

 22347.

genetic and biochemical analyses of the Cdc48 lethal mutant strongly suggested that when in complex with the 20S proteasome, essential proteins are abnormally forced to thread through the Cdc48 pore to become degraded.[Cdc48] (Mus musculus) PubMed

 22348.

the mechanism of PBS1 functioning in plant innate immunity, was investigated.[PBS1] (Mus musculus) PubMed

 22349.

The comparison of the conformational free energy landscapes using principal component analysis of the enzyme in absence or in presence of sucrose, also revealed a more harmonic basin when sucrose is bound with a shift population of the bending mode, consistent with the substrate binding event. [sucrose] (Mus musculus) PubMed

 22350.

infection by M. oryzae strain Guy11 specifically induced the expression of rice miR319 and, consequently, suppressed its target gene TEOSINTE BRANCHED/CYCLOIDEA/PROLIFERATING CELL FACTOR1.[miR319] (Mus musculus) PubMed

 22351.

These results indicate that residues 199-316 of Porphyromonas gingivalis Hgp44 are mainly responsible for adhesion to Treponema denticola; inhibiting this domain could potentially disrupt periodontopathic biofilm formation and maturation.[Hgp44] (Mus musculus) PubMed

 22352.

Small Angle X-ray Scattering data suggests that the protein adopts a closed and more stable conformation upon ion binding. (Mus musculus) PubMed

 22353.

Pi17316 interacts directly with the potato ortholog of VASCULAR HIGHWAY1-interacting kinase (StVIK), encoding a predicted MEK kinase (MAP3K).Pi17316] (Mus musculus) PubMed

 22354.

Pi17316 interacts directly with the potato ortholog of VASCULAR HIGHWAY1-interacting kinase (StVIK), encoding a predicted MEK kinase (MAP3K).[StVIK] (Mus musculus) PubMed

 22355.

The present study showed that rstA and rstB silencing resulted in impaired adhesion, biofilm production, motility, hemolysis, and virulence.[rstA, rstB] (Mus musculus) PubMed

 22356.

Study identified a SQD2-like enzyme, designated as SQD2.2, in rice. SQD2.2 was found to be a UGT enzyme that catalyzes the glycosylation of apigenin to produce apigenin 7-O-glucoside but no detectable sulfoquinovosyldiacylglycerol synthase activity. Its overexpression enhances flavonoid accumulation, resulting in a reduced seed setting rate and diminished tiller number accompanied by a reduced starch content. [SQD2.2] (Mus musculus) PubMed

 22357.

These results suggest that TaCIPK23 plays important roles in abscisic acid (ABA) and drought stress responses, and mediates crosstalk between the ABA signaling pathway and drought stress responses in wheat. [CIPK23] (Mus musculus) PubMed

 22358.

Study provides genetic and biochemical evidence of c-di-GMP degradation by the EAL domain of BsmR protein. As a regulatory protein, BsmR was shown to modulate the expression of 349 genes. Although its inactivation did not remarkably impact bacterial swimming or biofilm formation, the increase in the protein expression resulted in an increase in cellular swimming capability and decrease in biofilm development. [Bsm] (Mus musculus) PubMed

 22359.

We used this assay to investigate why kinetochores recruit the microtubule-binding Ndc80 complex via two receptors: the Mis12 complex and CENP-T. Although the CENP-T pathway is non-essential in yeast, we demonstrate that it becomes essential for viability and Ndc80c recruitment when the Mis12 pathway is crippled by defects in Dsn1 phosphorylation (Mus musculus) PubMed

 22360.

contributes to agronomically important traits including flowering time and grain size - [PSTOL] (Mus musculus) PubMed

 22361.

We hypothesize based on our results that Divalent Metal Transporter 1(DMT1) in B. malayi functions as an iron transporter. The presence of this transporter in the intestine supports the hypothesis that iron acquisition by adult females requires oral ingestion and suggests that the intestine plays a functional role in at least some aspects of nutrient uptake [DMT1]. (Mus musculus) PubMed

 22362.

To characterize the structural basis of protein trafficking in the Plasmodium knowlesi-infected erythrocyte, we identified a P. knowlesi ortholog of MAHRP2, a marker of the tether structure that connects membranous structures in the P. falciparum-infected erythrocyte. We show that PkMAHRP2 localizes on amorphous structures that connect Sinton Mulligan's clefts (SMC) to each other and to the erythrocyte membrane [MAHRP2]. (Mus musculus) PubMed

 22363.

GlgP2 is the crucial enzyme for glycogen degradation. [GlgP2] (Mus musculus) PubMed

 22364.

that IL29, IL28B, and IL28R interfere in the infection of HTLV-1-associated myelopathy/tropical spastic paraparesis, mainly via Tax activation (Mus musculus) PubMed

 22365.

The H. pylori isolates of gastric cancer subjects had a higher rate of HtrA-L171. H. pylori isolates with presence of both HtrA-171 & CagL-Y58/E59 can synergistically increase the risk of gastric cancer.[HtrA; CagL] (Mus musculus) PubMed

 22366.

Tal7 activates the expression of rice gene Os09g29100 that suppresses avrXa7-Xa7 mediated defense in Rice.[Tal7] (Mus musculus) PubMed

 22367.

Tal7 activates the expression of rice gene Os09g29100 that suppresses avrXa7-Xa7 mediated defense in Rice.[Os09g29100] (Mus musculus) PubMed

 22368.

These results suggest that PfRON12 might be a potential blood-stage vaccine candidate antigen against P. falciparum [RON12]. (Mus musculus) PubMed

 22369.

Data report a single domain hyper-transglycosylating chitinase, which generates longer chitin oligosaccharides (CHOS). EcChi1 was optimally active at pH 5.0 and 40 degrees C. EcChi1 showed both chitobiase and TG activities, in addition to hydrolytic activity. Homology modeling and docking with CHOS suggested that EcChi1 has a deep substrate-binding groove lined with aromatic amino acids. [Chi1] (Mus musculus) PubMed

 22370.

involved in Lr35-mediated adult wheat defense in response to leaf rust attack - [Lr35PR5] (Mus musculus) PubMed

 22371.

Newly identified essential amino acids affecting chlorella ellipsoidea DGAT1 function revealed by site-directed mutagenesis have been described. [DGAT1] (Mus musculus) PubMed

 22372.

Altogether, these data show that a csrB gene duplication event in Vibrio tasmaniensis supported the evolution of the regulatory network controlling the expression of major toxic secreted metalloproteases, thereby increasing redundancy and enabling the integration of additional input signals.[csrB] (Mus musculus) PubMed

 22373.

Characterization of a Carbonyl Reductase from Rhodococcus erythropolis WZ010 and Its Variant Y54F for Asymmetric Synthesis of (S)-N-Boc-3-Hydroxypiperidine. (Mus musculus) PubMed

 22374.

Results revealed that histatin-5 is able to revert MDR phenotype and may be considered a potential alternative MDR inhibitor. Since Pdr5p is homologous to Candida albicans CaCdr1p and CaCdr2p, data obtained might be extrapolated to these transporters, inferring that associating fluconazole and histatin-5 may be a useful tool to circumvent failure treatments of infections caused by Candida MDR strains [Pdr5p]. (Mus musculus) PubMed

 22375.

Site-directed mutagenesis showed key amino acids (Glu98 and Trp10) of PlyP40 involved in catalysis and substrate stabilization. [PlyP40] (Mus musculus) PubMed

 22376.

LytM factor Alr3353 regulates nanopore formation and cell-cell communication by directly interacting with AmiC1. [LytM] (Mus musculus) PubMed

 22377.

Substitution of leucine at position 10 of PmrB with other amino acids (glycine and glutamine) resulted in loss of function, underscoring a key role of this residue which is located in the cytoplasmic secretion domain of the protein.[PmrB] (Mus musculus) PubMed

 22378.

Ankyrin protein AnkB can affect the gene expression of catB, catalase activity, and sensitivity to H2O2 In Xanthomonas spp., the locations of genes ankB and catB and the amino acid sequence of AnkB are highly conserved [AnkB]. (Mus musculus) PubMed

 22379.

SE1 is a phospholipase-like protein that controls the synthesis of galactolipids in rice endosperm and provide a novel connection between lipid metabolism and starch synthesis in rice grains during endosperm development.[FSE1] (Mus musculus) PubMed

 22380.

FDML1 ole in flower development.MADS6 directly targets FDML1 gene.[FML1] (Mus musculus) PubMed

 22381.

Therefore, PCV2 ORF5 might have an inhibitory role against host immune surveillance [ORF5]. (Mus musculus) PubMed

 22382.

the diminishing of erythrophagocytosis by silencing the Ehtbp gene indicate the different physiological roles of these transcription factors in E. histolytica [TBP]. (Mus musculus) PubMed

 22383.

The data support RON2 as a novel B. bovis vaccine candidate antigen that contains conserved B-cell epitopes that elicit partially neutralizing antibodies [RON2]. (Mus musculus) PubMed

 22384.

Salt-induced expression of miR390 during lateral roots development.[miR390] TAS3 is a key regulator, via the auxin pathway, of lateral roots development during salt stress.[TAS3] ARF4 negatively regulates plant growth and salt tolerance.[ARF4] (Mus musculus) PubMed

 22385.

Data indicate that reduced levels of TcSTI1 decrease the rate of in vitro metacyclogenesis, suggesting that this protein may participate in the differentiation process of T. cruzi [STI1]. (Mus musculus) PubMed

 22386.

Immunoprecipitation of T. gondii-infected CHO cell lysates showed that TgRON4 interacts with glypican 1 during Toxoplasma invasion. This interaction suggests a role for heparan sulfate in parasite invasion [RON4]. (Mus musculus) PubMed

 22387.

We identified a CheZ-like protein among Alphaproteobacteria functioning in chemotaxis and the A. caulinodans-S. rostrata symbiosis [CheZ]. (Mus musculus) PubMed

 22388.

This study reports recombinant Leishmania donovani co-factor-independent phosphoglycerate mutase (rLd-iPGAM) as an effective immunoprophylactic agent, which can be used in future vaccine design [iPGAM]. (Mus musculus) PubMed

 22389.

PcntK promoter activity is attenuated by the repeated sequence and strictly controlled by Fur or Zur binding to its respective target sequences.[Zur] (Mus musculus) PubMed

 22390.

The findings indicated that intense cell-mediated and humoural immunity was triggered and that defence mechanisms against T. gondii were partially induced after vaccination by Toxoplasma gondii rhoptry proteins (TgROP35) [TgROP35]. (Mus musculus) PubMed

 22391.

The finding of OppA4 involved in regulation of the Rrp2-RpoN-RpoS pathway further reinforces the importance of nutritional virulence to the enzootic cycle of B. burgdorferi [OppA4]. (Mus musculus) PubMed

 22392.

The aim of this study was to analyze the effect of the 220 kDa lectin of Entamoeba histolytica on stimulation of human macrophages and neutrophils. L220 has a cytokine stimulating function of macrophages and neutrophils for secretion of IL-1beta, and IL-10 only by macrophages, which was modulated by the effect of vecuronium on cholinergic receptors in this immune cells [L220]. (Mus musculus) PubMed

 22393.

Phenotypic analysis of Plasmodium berghei ron12-disrupted mutants revealed that RON12 is dispensable for sporogony, invasion of mosquito salivary glands and mouse hepatocytes, and development in hepatocytes [RON12]. (Mus musculus) PubMed

 22394.

A tannase gene from A. niger was cloned, overexpressed and characterized in a low-background A. niger strain to enable high-level production and simple purification of tannase. (Mus musculus) PubMed

 22395.

These results suggested that the THA_1941-encoded enzyme was the first enzyme having both cellodextrin and cellobiose phosphorylases activities. Because it preferred cellobiose and cellodextrins to glucose in the synthetic direction, it was categorized as a cellodextrin phosphorylase (CDP).[THA_1941] (Mus musculus) PubMed

 22396.

Deleting RON1 partially restored the ability of an ndt80Delta mutant to form hyphae in response to N-acetylglucosamine, indicating a link to N-acetylglucosamine signaling. REP1 was required for growth on N-acetylglucosamine, as expected, but not for N-acetylglucosamine or serum to induce hyphae.[RON1] (Mus musculus) PubMed

 22397.

The present study highlighted that AsaI/C4-HSL was an important regulator in spoilage, motility and biofilm formation of A. salmonicida, and spoilage potential was under the negative control of AsaI/AsaR-type system [Asal]. (Mus musculus) PubMed

 22398.

Two genes encoding mRNA cap methyltransferases have been identified in T. brucei: TbCMT1 and TbCGM1. TbCMT1 is not essential to bloodstream form T. brucei growth in vitro or in vivo but it contributes significantly to parasite virulence in vivo. [TbCMT1] (Mus musculus) PubMed

 22399.

Aspf2 has been identified as the first A. fumigatus Factor H-binding protein. Aspf2 recruits several human plasma regulators, Factor H, factor-H-like protein 1 (FHL-1), FHR1, and plasminogen.Aspf2 is a central immune evasion protein and plasminogen ligand of A. fumigatus. By blocking host innate immune attack and by disrupting human lung epithelial cell layers, Aspf2 assists in early steps of fungal infection and likely a (Mus musculus) PubMed

 22400.

The product of RLS1 is presumed to be a critical component of the rice oxidative stress response and is involved in ROS (reactive oxygen species)-mediated leaf senescence. [RLS1] (Mus musculus) PubMed

 22401.

integrative genomics validate as candidate gene for the stony hard trait - [YUC11-like] (Mus musculus) PubMed

 22402.

the role of calcineurin during vegetative growth of Dictyostelium discoideum (calcineurin) (Mus musculus) PubMed

 22403.

regulator of grain protein content - [AAP6-3B] (Mus musculus) PubMed

 22404.

HL1 single-nucleotide polymorphisms affects leaf hair number.[HL1] (Mus musculus) PubMed

 22405.

Exposing Voltage-gated Ca2+ channel (CaV) Ab channel to 1, 2, 3, 4, and 5 GHz electric fields increases the depth of the potential energy well and this may result in an increase in the affinity and strength of Ca(2+) ions to binding sites in the selectivity filter the channel. [CaV Ab] (Mus musculus) PubMed

 22406.

HemW is required for the insertion of heme b into respiratory chain enzymes. [HemW] (Mus musculus) PubMed

 22407.

Whereas the Staphylococcus aureus SPIN N terminus adopts a beta-hairpin confirmation upon binding to MPO, the solution NMR studies presented here are consistent with this region of SPIN being dynamically structured in the unbound state. [SPIN] (Mus musculus) PubMed

 22408.

a maize SWI3D protein, ZmCHB101, impacts alternative splicing contexts in response to osmotic stress.[ZmCHB101] (Mus musculus) PubMed

 22409.

This study concluded that OsSPK1 is a direct and key signaling target of Pit-mediated immunity via RAC1 activation.[SPK1] (Mus musculus) PubMed

 22410.

Simulated results provide a detailed characterization of insertion, orientation and phosphatidylinositol 4,5-bisphosphate (PIP2) -interaction of NS3 protease domain at membrane environment, thus enhancing the understanding of structural functions and mechanism for the association of Hepatitis C virus non-structure 3 protein with respect to endoplasmic reticulum membranes. [NS3 protease ] (Mus musculus) PubMed

 22411.

GARS was involved in chloroplast development at early leaf development by affecting the expression of plastid-encoded genes.[GARS] (Mus musculus) PubMed

 22412.

Pep-13 triggers immunity in a SERK3/BAK1-independent manner, similar to chitin.[BAK1] (Mus musculus) PubMed

 22413.

[Mca1] Maximal transcriptional induction of mfc1+ was observed in response to copper deficiency and that Mca1 was constitutively bound to the mfc1+ promoter irrespective of changes in copper concentrations. Optimal induction of mfc1+ transcription coincided with maximal chromatin occupancy by RNA Pol II under low copper conditions.There was a lack of RNA Pol II recruitment at the mfc1+ locus in response to excess copper. (Mus musculus) PubMed

 22414.

The present study reports MdDREB76 as a key regulator that switches on the battery of downstream genes which impart salt and osmotic stress endurance. (Mus musculus) PubMed

 22415.

The authors found that loss of rnst-2 causes accumulation of rRNA and ribosomal proteins in enlarged lysosomes and both phenotypes are suppressed by blocking autophagy, which indicates that RNST-2 mediates autophagic degradation of ribosomal RNA in lysosomes.[rnst-2] (Mus musculus) PubMed

 22416.

our results suggest that manipulating p13 expression may be a promising avenue for therapeutic intervention in Parkinson's disease (Mus musculus) PubMed

 22417.

These data suggest that TrxA not only mediates Acinetobacter baumannii gastrointestinal tract colonization but also may contribute to pathogenesis in Acinetobacter baumannii sepsis following escape from the gastrointestinal tract under conditions when the intestinal barrier is compromised, as occurs with cases of severe shock and trauma.[TrxA] (Mus musculus) PubMed

 22418.

Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases: The Structures of Picrophilus torridus 2-Keto-3-deoxygluconate Aldolase and Sulfolobus solfataricus 2-Keto-3-deoxy-6-phosphogluconate Aldolase in Complex with 2-Keto-3-deoxy-6-phosphogluconate. (Mus musculus) PubMed

 22419.

Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases: The Structures of Picrophilus torridus 2-Keto-3-deoxygluconate Aldolase and Sulfolobus solfataricus 2-Keto-3-deoxy-6-phosphogluconate Aldolase in Complex with 2-Keto-3-deoxy-6-phosphogluconate. (Mus musculus) PubMed

 22420.

Alpha-toxin role in the platelet aggregation during Staphylococcus aureus sepsis.[Alpha-toxin] (Mus musculus) PubMed

 22421.

Binding assays revealed that the Cry9Aa and Vip3Aa proteins interacted with high affinity. [Cry9Aa, Vip3Aa] (Mus musculus) PubMed

 22422.

During a substrate-specificity screening it was confirmed that haloalkane dehalogenase, DhlA, can catalyze the conversion of bulky substrates, such as the 4-(bromomethyl)-6,7-dimethoxy-coumarin. [haloalkane dehalogenase] (Mus musculus) PubMed

 22423.

PeMIPS1 was not only inducible by drought and high salinity, but also by CuSO4 treatment. The transgenic poplar lines overexpressing PeMIPS1 had greater plant heights, shoot biomasses and survival rates than the wild type during the salt- or copper-stress treatment, and this was accompanied by an increase in the myo-inositol content.[MIPS1] (Mus musculus) PubMed

 22424.

role of conserved non-aromatic residues in the Lactobacillus amylovorus alpha-amylase CBM26-starch interaction [alpha-amylase] (Mus musculus) PubMed

 22425.

BTB protein MdBT2 had a negative role in the biosynthesis of anthocyanin and proanthocyanidin. MdBT2 interacted with MdMYB9 and negatively regulated the abundance of MdMYB9 protein through the 26S proteasome system.[BT2] (Mus musculus) PubMed

 22426.

PvdO of Pseudomonas fluorescens A506 is required for the final oxidation of dihydropyoverdine to pyoverdine. [PvdO] (Mus musculus) PubMed

 22427.

SigX is the missing link in overproduction of ComR.[SigX, ComR] (Mus musculus) PubMed

 22428.

the deletion of celA triggers a strong phenotype reminiscent of cell wall-related aberrations and the upregulation of some secondary metabolite gene clusters in A. nidulans.[celA] (Mus musculus) PubMed

 22429.

In this study, the authors show that AerR is translated as two isoforms that differ by 41 amino acids at the amino terminus. Pigmentation and transcriptomic analyses show that the short AerR variant represses, while long variant activates, photosynthesis genes.[AerR] (Mus musculus) PubMed

 22430.

NopP positively and negatively affected the nodule number (NN) and nodule dry weight (NDW), while NopP had different effects on NN and NDW in other soybean germplasms.[NopP] (Mus musculus) PubMed

 22431.

Using a murine model of Salmonella infection, this study showed that a strain lacking all three transketolases is avirulent in C57BL/6 mice, TktA, TktB, TktC. [TktA, TktB, TktC] (Mus musculus) PubMed

 22432.

Using in vivo photo-cross-linking and molecular dynamics simulations, the study established that MlaA interacts extensively with OmpC and is located entirely within the lipid bilayer. [MlaA, OmpC] (Mus musculus) PubMed

 22433.

exogenous BDNF mitigates neuronal metabolic defects following mechanical injury by promoting the phospho CREB accumulation in mitochondrial inner membrane and matrix, which is regulated by MPTP opening (Mus musculus) PubMed

 22434.

the X-ray structure of the bacterial polysialyltransferase [PST] from Mannheimia haemolytica serotype A2, is described.[PST] (Mus musculus) PubMed

 22435.

Structural analysis and modeling of EhACK indicated steric hindrance by active site residues constricts entry to the adenosine pocket as compared to ATP-utilizing Methanosarcina thermophila ACK.[Acetate kinase] (Mus musculus) PubMed

 22436.

field-collected Ugandan Culex quinquefasciatus display copy number variation for the voltage-gated sodium channel gene (Vgsc), target-site of pyrethroid and organochlorine insecticides.[Vgsc] (Mus musculus) PubMed

 22437.

Overall, vacA genotype was significantly associated with clinical outcomes, as vacA subtypes: s1a1b, s1as1bm2, s2 m2 and m2, s1bm2 were significantly correlated to gastritis, whereas, subtypes s1 am1, s1 am2, m1were significantly associated with gastric and duodenal ulcers. The subtype vacA s1bm2 was associated with gastritis in 5 cases (45.5%) and with duodenal ulcer in 4 cases (36.4%). (vacA, cagA and iceA). (Mus musculus) PubMed

 22438.

In contrast to naturally occurring G6PD variants in the human host that can alter the kinetic properties of the enzyme and thus the redox homeostasis of the cells, the naturally occurring PfGluPho variants studied here are unlikely to have a major impact on the parasites' redox homeostasis.[GluPho] (Mus musculus) PubMed

 22439.

The results show that the PvRON2 structure, particularly the S-S bond between C2051 and C2063, is determinant for the existence of the interaction between PvAMA1 and PvRON2.[RON2] (Mus musculus) PubMed

 22440.

Sir2La is the first sirtuin from Lactobacillales and of the Gram-positive bacterial subclass of sirtuins to be functionally characterized. The ability to hydrolyze propionyl- and butyryllysine emphasizes the relevance of further exploring the role of other short-chain acyl moieties as PTMs. (Mus musculus) PubMed

 22441.

results show that inositol pyrophosphate multikinase (Kcs1) functions to fine-tune inositol acquisition to maintain inositol homeostasis in C. neoformans [Kcs1]. (Mus musculus) PubMed

 22442.

An acidic residue at both position 277 and 282 of Fdc1 is required for activity. [Fdc1] (Mus musculus) PubMed

 22443.

The authors made double mutants and found that lapA plaC mutants have an ~50-fold defect during infection of Acanthamoeba castellanii.[lapA, plaC] (Mus musculus) PubMed

 22444.

In this study,a novel component of the flagellar filament, FcpB was identified in Leptospira biflexa. FcpB is crucial for the ability of Leptospira cells to generate high velocity during translational motility. [FcpB] (Mus musculus) PubMed

 22445.

Here, crystal structures of a glycoside hydrolase family 113 beta-1,4-mannanase from Amphibacillus xylanus (AxMan113A) and its complexes with mannobiose, mannotriose, mannopentaose, and mannahexaose were solved. [beta-1,4-mannanase] (Mus musculus) PubMed

 22446.

[Mpr1] Through structure-function analysis of Mpr1, study identified the prodomain cleavage sites of Mpr1 and demonstrated that when mutated, the prodomain appears to remain attached to the catalytic C-terminus of Mpr1 rendering a nonfunctional Mpr1 protein and an inability for cryptococci to cross the BBB. Proteolytic activity of Mpr1 was dependent on the coordination of zinc with 2 histidine residues in the active site. (Mus musculus) PubMed

 22447.

H. pylori stool shedding and EPIYA-D cagA alleles are associated with gastric cancer in an East Asian hospital [cagA] (Mus musculus) PubMed

 22448.

This study looked to discern the structural and chemical features within the tyrosine aminomutase active site and active site loop that govern its high enantioselectivity and to parse the principles that define the mutase and lyase activities. [tyrosine aminomutase] (Mus musculus) PubMed

 22449.

the balance of PUP-1, PUP-2 and PUP-3 activities appears to ensure proper germline development.[PUP-1, PUP-2, PUP-3] (Mus musculus) PubMed

 22450.

CshA-AMP structure reveals the role of the hydrophobic residue Phe22 in the Q motif and Lys52 in motif I.Phe22 in the Q motif and Lys52 in motif I are essential for ATP binding.[CshA] (Mus musculus) PubMed

 22451.

BpeB crystall structure.[BpeB] (Mus musculus) PubMed

 22452.

This study reports the crystal structures of ligand-free transcriptional regulator CouR as well as the complex with p-coumaroyl-CoA, each to 2.1-A resolution, and the 2.85-A resolution cocrystal structure of CouR bound to an oligonucleotide bearing the cognate DNA operator sequence. [CouR] (Mus musculus) PubMed

 22453.

Located in the cerecidin gene cluster, cerR encodes a putative response regulator protein that belongs to the LuxR family transcriptional regulators. CerR (84 amino acids) contains only a conserved DNA binding domain and lacks a conventional phosphorylation domain, which is rarely found in lantibiotic gene clusters.[CerR] (Mus musculus) PubMed

 22454.

Data found that BmEm4, an ortholog of E(spl)m4 from Bombyx mori, was the target gene of bmo-miR-79, with target sites containing the Brd and K boxes of the BmEm4_3'UTR (Em4). (Mus musculus) PubMed

 22455.

NahE and PhdJ are bifunctional hydratase-aldolases in bacterial catabolic pathways for naphthalene and phenanthrene, respectively. This study report the structures of NahE, and PhdJ covalently bound to substrate via a Schiff base. Structural analysis and dynamic light scattering experiments show that both enzymes are tetramers. [PhdJ] (Mus musculus) PubMed

 22456.

substrate specificity and relation to remodeling cell wall structure in response to inclination - [XTH1] (Mus musculus) PubMed

 22457.

regulates cold-induced sweetening of tubers by inactivation of StBAM1 - [RFP1] (Mus musculus) PubMed

 22458.

This study reports the first structure of CAMP factor, revealing a structural fold composed of 5 + 3-helix bundles. Further analysis by protein truncation and site-directed mutagenesis indicated that the N-terminal 5-helix bundle is responsible for membrane permeabilization, whereas the C-terminal 3-helix bundle is likely responsible for host receptor binding. [CAMP factor] (Mus musculus) PubMed

 22459.

H. pylori isolated from patients in Guizhou region, China, showed a unique genotype, which was mainly East Asiatype cagA (ABD), vacA s1c/m2 genotype or iceA1postiive. (Mus musculus) PubMed

 22460.

These results indicate that the duplication of the PTAP motif in the p6 Gag protein enhances the replication fitness of HIV-1C by engaging the Tsg101 host protein with a higher affinity. [p6 Gag protein] (Mus musculus) PubMed

 22461.

[YbgC] YbgC is essential for S. Enteritidis survival in egg white. (Mus musculus) PubMed

 22462.

Although Streptococcus agalactiae grows well in vitro by fermentative metabolism, it is shown here that the absence of NDH-2 results in attenuated virulence, as observed by reduced colonization in heart and kidney in a mouse model of systemic infection.[NDH-2] (Mus musculus) PubMed

 22463.

Sentryn and SAD Kinase Link the Guided Transport and Capture of Dense Core Vesicles in Caenorhabditis elegans [sentry] (Mus musculus) PubMed

 22464.

Sentryn and SAD Kinase Link the Guided Transport and Capture of Dense Core Vesicles in Caenorhabditis elegans (Mus musculus) PubMed

 22465.

Status of Artemisinin Resistance in Malaria Parasite Plasmodium falciparum from Molecular Analyses of the Kelch13 Gene in Southwestern Nigeria. (Mus musculus) PubMed

 22466.

RpoB mutations in in polydrug-resistant M. tuberculosis isolates.[RpoB] (Mus musculus) PubMed

 22467.

Wheat genotypes carrying Yr34 and Yr48 produced identical haplotypes for the Yr34-linked markers identified in this study and those previously reported to be linked with Yr48. The results strongly suggest that Yr34 and Yr48 are the same gene, and that Yr48 should be considered a synonym of Yr34.[Yr34,Yr48] (Mus musculus) PubMed

 22468.

a root specific promoter of OsPT2, a low-affinity Pi transporter - [Os03g01700] (Mus musculus) PubMed

 22469.

catalyzes a unique two-step reaction whereby the 2'-PO4 attacks NAD(+) to form an RNA-2'-phospho-ADP-ribosyl intermediate that undergoes transesterification to yield 2'-OH RNA and ADP-ribose-1'',2''-cyclic phosphate products [Tpt1] (Mus musculus) PubMed

 22470.

This study reports the incorporation of 1,2-propanediol, 3-fluoro-1,2-propanediol, and 3,3,3-trifluoro-1,2-propanediol into the 5'-terminus of DNA and RNA oligonucleotides and the analysis of their hydroxide-catalyzed and HDV ribozyme-catalyzed cleavage reactions, respectively. [ribozyme] (Mus musculus) PubMed

 22471.

It unexpectedly observed that certain substrates (LPATXG, X=Nle, Leu, Phe, Tyr) were susceptible to transacylation at alternative sites within the substrate motif, and sortase A from S. pneumoniae was capable of forming oligomers. Overall, this work provides a foundation for the further development of sortase enzymes for use in protein modification. (Mus musculus) PubMed

 22472.

A heme-inducible operon was identified that contains a TetR family transcriptional regulator and major-facilitator superfamily transporter. We have named these gene products HatRT for heme activated transporter (R = regulator, T = transporter). (Mus musculus) PubMed

 22473.

this study, salivaricin A2 was purified and its covalent structure was characterized. Analogue salivaricin A2(3-22) has no antibacterial activity and does not have an antagonistic effect on the native compound.[Salivaricin A2] (Mus musculus) PubMed

 22474.

The data support PRUPE.6G281100 (LRR-RLK) as a candidate gene for flat shape in peach. [LRR-RLK] (Mus musculus) PubMed

 22475.

This study presents the structure of the N-terminal DNA-binding domain of Helicobacter pylori LlaJI.R1 at 1.97-A resolution, which adopts a B3 domain fold. [LlaJI.R1 ] (Mus musculus) PubMed

 22476.

miR-30b inhibits the expression of Dynamin in inner hair cells by targeting DNM11 gene. [miRNA30b] (Mus musculus) PubMed

 22477.

The oipA gene was found to be associated with the development of chronic gastritis, and the "on" status of the gene was the most frequent in patients with gastric cancer who were from Western countries. [oipA] (Mus musculus) PubMed

 22478.

Mutation of gumB conferred a severe loss of the secondary metabolites prodigiosin and serratamolide. The gumB mutation conferred pleiotropic phenotypes, including altered biofilm formation, highly increased capsular polysaccharide production, and loss of swimming and swarming motility.[gumB] (Mus musculus) PubMed

 22479.

alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), the enzyme that limits spontaneous cyclization of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde in the de novo NAD(+) synthesis pathway, controls cellular NAD(+) levels via an evolutionarily conserved mechanism in Caenorhabditis elegans and mouse [ACMSD] (Mus musculus) PubMed

 22480.

MscCG2 was predicted to possess three transmembrane helices in the N-terminal region and located in the cytoplasmic membrane, which are typical structural characteristics of the mechanosensitive channel of small conductance. MscCG2 has a low amino acid sequence identity (23%) to MscCG and evolved separately from MscCG with four transmembrane helices.[MscCG2] (Mus musculus) PubMed

 22481.

This study presents the first S-oxygenated heterobimetallic [NiFe] complex as a structural and spectroscopic model for the S-oxygenated active site of the NAD+-reducing NiFe hydrogenase from Ralstonia eutropha. [NiFe hydrogenase] (Mus musculus) PubMed

 22482.

a transcription factor, Encystation Regulatory Motif-Binding Protein (ERM-BP), that regulates encystation, was identified.[ERM-BP] (Mus musculus) PubMed

 22483.

The accessory gene regulator (Agr) operon is one of the Staphylococcus genus QS systems. Three groups (I, II, and III) are present in Staphylococcus epidermidis Agr operon.In Staphylococcus epidermidis , a symbiotic association of competition and antagonism occurs among different Agr groups during biofilm formation. (Mus musculus) PubMed

 22484.

Amino acid variation at position 215 of PhoP causes subtle changes in the PhoP activity, which raises the possibility that the change in this residue has contributed to the evolution of increased virulence in Y. pestis [PhoP]. (Mus musculus) PubMed

 22485.

Two arginine decarboxylases (Adc1 and Adc2) possess function in the polyamine synthesis pathway. Inactivation of the adc1 and adc2 genes leads to biofilm formation even in the absence of salt. [Adc1; Adc2] (Mus musculus) PubMed

 22486.

AC5 was not a component of the PIF complex, while the deletion of ac5 did not affect the formation and presence of the PIF complex. [Ac5] (Mus musculus) PubMed

 22487.

We present evidence for the functional overlap of hetP and hetZ and for the key role of the HetR-HetP/HetZ circuit in regulation of heterocyst differentiation. [HetP; HetZ] (Mus musculus) PubMed

 22488.

In the present study, the authors found that the mutations in the C-terminus of NS1 affected NP1 function in viral replication. The result suggested that NP1 facilitated the replication of viral genome but was not essential.[NS1, NP1] (Mus musculus) PubMed

 22489.

Results show the cloning and characterization of two copies of CSAD genes found in the genome. Under salinity treatment, CSAD1 expression increased significantly but note CSAD2. Results of CSAD1 interference provided the evidence of the positive correlation between CSAD1 expressions and taurine. The zinc finger domain may play an important role for CSAD1 as the key enzyme in taurine biosynthesis. [CSAD1 and CSAD2] (Mus musculus) PubMed

 22490.

This study determined the structure of S-(+)-1-Amino-2-propanol dehydrogenase (APDH) in both apo form (at 1.7 A) and as a ternary enzyme complex with NADP+ and aminoacetone (at 1.9 A). [APDH] (Mus musculus) PubMed

 22491.

UDP-galactopyranose mutase (UGM) from the pathogenic fungus Aspergillus fumigatus also catalyzes the isomerization of UDP-arabinopyranose (UDP-Ara p), which differs from UDP-Gal p by lacking a -CH2-OH substituent at the C5 position of the hexose ring. [UDP-Galactopyranose Mutase] (Mus musculus) PubMed

 22492.

Study results support that GpsB functions as an adaptor protein that mediates the interaction between membrane proteins, scaffolding proteins, signaling proteins and enzymes to generate larger protein complexes at specific sites in a bacterial cell cycle-dependent manner.(GpsB) (Mus musculus) PubMed

 22493.

knockdown of OsDCL3b will affect the biogenesis of small RNAs, which is involved in regulating the transcription of mRNA genes, and consequently influence the grain yield and quality in rice. (Mus musculus) PubMed

 22494.

Deletion of the mtlD gene from A. baumannii ATCC 19606 cells no longer accumulated mannitol and growth was completely impaired at high salt. [mtlD] (Mus musculus) PubMed

 22495.

Knocking out of Yki led to reduced body size, moulting defects and, eventually, larval lethality. [Yorkie] (Mus musculus) PubMed

 22496.

affects plant architecture and seed yield component - [AP1] (Mus musculus) PubMed

 22497.

Helicobacter pylori (Hp) heat shock protein 60 (HspB) shared a specific epitope (P1 peptide) with human heat shock protein (Hsp)60. Hp-positive patients with gastritis or coronary heart disease produce IgG autoantibodies specific to P1. Upregulation of proinflammatory cytokines by P1 contributes to the pathogenesis of Hp infection and the autoimmunity as a result of molecular mimicry. (Mus musculus) PubMed

 22498.

The X-ray crystal structure of Nicotine oxidoreductase (NicA2) with S-nicotine refined to 2.65 A resolution reveals a hydrophobic binding site with a solvent exclusive cavity. [NicA2] (Mus musculus) PubMed

 22499.

DnaK induces ClpB to dissociate from the polypeptide substrate. DnaK acts as a peptide release factor, binding ClpB and causing the ClpB conformation to change to a low-peptide affinity state. [ClpB, DnaK] (Mus musculus) PubMed

 22500.

Sequencing analysis of clinical ampicillin-resistant Enterococcus faecium isolates with minimum inhibitory concentrations (MICs) for ampicillin in the ranges from 128 to >512 mug/mL reveals five different class B penicillin-binding protein 5 (PBP5) alleles having differences in 18 amino acid positions. (Mus musculus) PubMed

 22501.

IutA and IutE are both ABC Metal Transporter membrane proteins with comparable Mn and Zn binding abilities [IutE; IutA] (Mus musculus) PubMed

 22502.

The cloned easI protein (~25 kDa) shares high similarity to members of the LuxI and is a functional AHL synthase. [easI] (Mus musculus) PubMed

 22503.

Crystal structures of the cobalamin-dependent methionine synthase (MetH) reactivation domain in complex with S-adenosylmethionine (AdoMet), the methyl transfer product S-adenosylhomocysteine (AdoHcy), and the AdoMet analogue inhibitor sinefungin illustrate that the ligands exhibit an analogous conformation within the solvent-exposed substrate binding cleft of the enzyme. [MetH] (Mus musculus) PubMed

 22504.

The nucleoid of an apically growing mycobacterium is positioned asymmetrically within the cell throughout the cell cycle. We show that HupB is involved in controlling the timing of replication initiation [HupB]. (Mus musculus) PubMed

 22505.

This study demonstrates that the outer membrane component SilC serves a specialized role in virulence of F. tularensis by conferring resistance against oxidative stress and silver [SilC]. (Mus musculus) PubMed

 22506.

PrtA Metalloprotease is a factor implicated in the persistence of S. marcescens on abiotic surfaces and in bacterial host colonization capacity. PrtA is involved in the ability of S. marcescens to develop biofilm [PrtA]. (Mus musculus) PubMed

 22507.

Here we demonstrate a role for ClpXP, a protease system widely conserved in bacteria, in anaerobic Fe(2+) resistance in both S. oneidensis and Escherichia coli. [ClpXP] (Mus musculus) PubMed

 22508.

MelF activities of the B. bacteriovorus transporter were comparable to those of the E. coli system assayed at a 1:1 M ratio of MalE to the transport complex.[MelF, MelE] (Mus musculus) PubMed

 22509.

Study demonstrates that Na-glutamine co-transport mediated by B0AT1 in villus cells is regulated by prostaglandins rather than leukotrienes in the chronically inflamed intestine. [B0AT1] (Mus musculus) PubMed

 22510.

HilE specifically binds to HilD but not to HilC or RtsA. HilE functions to restrict low-level HilD activity, preventing premature activation of Salmonella pathogenicity island 1 until positive inputs reach a threshold required to fully induce the system. [HilE] (Mus musculus) PubMed

 22511.

Crystal structures of SmPNP2 with different ligands were obtained and compare with PNP1 providing clues for the unique capacity of PNP2 to bind pyrimidines. Substitutions around PNP2 active site alter the architecture of the nucleoside base binding site thus permitting an alternative binding mode for nucleosides, with a 180 degrees rotation from the canonical binding mode. [PNP2] (Mus musculus) PubMed

 22512.

absence of cholic acid in this species due to inactivated CYP8B1 [CYP8B1] (Mus musculus) PubMed

 22513.

The oxidoreductase NADPH-dependent assimilatory sulfite reductase (SiR) is composed of two subunits. One is a multidomain flavin binding reductase (SiRFP) and the other an iron-containing oxidase (SiRHP). SiRFP is a multidomain protein. SiRHP's N-terminal disordered region is critical for complex formation. [SiRFP, SiRHP] (Mus musculus) PubMed

 22514.

identification as a G2-like transcription factor that functions as a negative regulator of flowering = [PHL3] (Mus musculus) PubMed

 22515.

the Mmm1-Mdm12 complex functions as a minimal unit that mediates lipid transfer between membranes. (Mus musculus) PubMed

 22516.

SOPT/PIMMS2 is a conserved protein in Plasmodium that likely facilitates ookinete entry into the mosquito midgut to initiate traversal. [SOPT] (Mus musculus) PubMed

 22517.

Ras1 localized to the cytoplasm or endoplasmic reticulum (ER) is sufficient for GPI-GnT activation. [Ras1,GPI-GnT] (Mus musculus) PubMed

 22518.

the role of the proposed P. infestans Ggamma subunit gene, Pigpg1 (gpg1) (Mus musculus) PubMed

 22519.

LmNop56 remains associated with the nucleolus in nonproliferative cells.[Nop56] (Mus musculus) PubMed

 22520.

Here, we report that the first step of phenazine-1-carboxylic acid degradation by Mycobacterium fortuitum is catalyzed by a phenazine-degrading decarboxylase (PhdA) [PhdA]. (Mus musculus) PubMed

 22521.

X-ray structures of the major Vibrio cholerae porins, OmpU and OmpT show that both channels have narrow pore sizes and altered internal electric fields due to the presence of additional, unusual constriction elements. [OmpU & OmpT] (Mus musculus) PubMed

 22522.

PBP75 showed significant red color change after heat treatment and expression level was highest in hepatopancreas and weakest in muscle.[PBP75] (Mus musculus) PubMed

 22523.

modulates brassinosteroids-mediated growth regulation and influences architecture and grain shape - [GATA7] (Mus musculus) PubMed

 22524.

essential in the regulation of N starvation adaptation via modulating N acquisition and ROS homeostasis - [NBP1] (Mus musculus) PubMed

 22525.

results suggest that RLK5 functions as a positive regulator in drought tolerance [RLK5] (Mus musculus) PubMed

 22526.

This study investigates the structure and dynamics of the cold-shock protein of psychrophile Colwellia psychrerythraea 34h ( Cp-Csp). Cp-Csp lacks salt bridges and has longer flexible loops and a less compact hydrophobic cavity resulting from Tyr51 compared to mesophilic and thermophilic Csps. These might explain the low thermostability of Cp-Csp. [Cp-Csp] (Mus musculus) PubMed

 22527.

DNA-binding properties of MafR, a global regulator of Enterococcus faecalis. (Mus musculus) PubMed

 22528.

Helicobacter pylori binding to alpha5beta1 integrin under shear flow is dependent on the CagY, but independent of the presence of the T4SS pili, which are only formed when H. pylori is in contact with host cells.[CagY] (Mus musculus) PubMed

 22529.

Using single-molecule fluorescence resonance energy transfer (smFRET) and ensemble analyses, this study shows that RuvA stably binds to the Holliday Junction DNA, halting its conformational dynamics. (Mus musculus) PubMed

 22530.

Modest N-succinylamino acid racemase (NSAR) activity of Y299I o-succinylbenzoate synthase (OSBS) and epistasis between sites 18 and 299 indicate that additional sites influenced the evolution of NSAR reaction specificity in the NSAR/OSBS subfamily. [NSAR, OSBS] (Mus musculus) PubMed

 22531.

This L segment is 6,533 nucleotides in length and contains a single open reading frame (ORF) of 6,456 nucleotides in the antigenome sense that encodes the viral RNA-dependent RNA polymerase, which is 2,153 amino acids long with a predicted molecular mass of 246 kDa.[L protein] (Mus musculus) PubMed

 22532.

Helical Propensity Affects the Conformational Properties of the Denatured State of Cytochrome c' [cytochrome c'] (Mus musculus) PubMed

 22533.

contributes to high temperature stress tolerance involving in Dof transcriptional regulation and HSP protein expression - [GRAS2] (Mus musculus) PubMed

 22534.

This study reports the first adaptive QM/MM simulations of H(+) transfer through a biological channel, in particular, the protein EcCLC, a chloride channel (CLC) Cl(-)/H(+) antiporter derived from E. coli. [EcCLC] (Mus musculus) PubMed

 22535.

Study presents a pair of crystal structures of dimeric P-glycoprotein (ABCB1) from Cyanidioschyzon merolae, a transporter with quite similar functional properties to human P-gp9: an outward-facing nucleotide bound state (1.9 A resolution) and an inward-facing apo state (3.0 A). (ABCB1) (Mus musculus) PubMed

 22536.

This study profiled genome-wide expression for Sclerotinia sclerotiorum transcription factors in planta and in vitro and functionally characterized a novel transcription factor, SsC6TF1, which positively regulates sclerotial development and virulence on pea.[SsC6TF1] (Mus musculus) PubMed

 22537.

This study elucidated the role and mechanism of PFL (lncRNA NONMMUT022555, which is designated as a pro-fibrotic lncRNA (PFL)),in cardiac fibrosis, indicating that it is a competitive endogenous RNA (ceRNA) of Mirlet7d, as forced expression of PFL reduced the expression and activity of Mirlet7d.[lncRNA NONMMUT022555] (Mus musculus) PubMed

 22538.

The ahpD, along with cg2675-cg2678 genes, may play a novel role in cellular activities against oxidative stress. (ahpD protein) (Mus musculus) PubMed

 22539.

our study demonstrate that Adam12 and lnc015192 promote breast cancer metastasis partly by sponging miR-34a through the competitive endogenous RNA mechanism. (Mus musculus) PubMed

 22540.

constrains remodelling of the transcriptome and metabolome during submergence to facilitate post-submergence recovery - [SUB1A] (Mus musculus) PubMed

 22541.

cypin and cypinS play distinct roles in neuronal development.[Cypin] (Mus musculus) PubMed

 22542.

Multiple zinc ions maintain the open conformation of the catalytic site in the DNA mismatch repair endonuclease MutL from Aquifex aeolicus[MutL] (Mus musculus) PubMed

 22543.

Streptococcus pneumoniae AdcR (adhesin-competence repressor) regulates Zn(II) homeostasis and Zn(II) functions as an allosteric activator of DNA binding.[AdcR] (Mus musculus) PubMed

 22544.

PTEX is a bona fide translocon by determining structures of the PTEX core complex at near-atomic resolution using cryo-electron microscopy [EXP2, PTEX150, HSP101] (Mus musculus) PubMed

 22545.

Mannheimia haemolytica OmpP2-like is an amyloid-like protein, forms filaments, takes part in cell adhesion and is part of biofilms. [OmpP2] (Mus musculus) PubMed

 22546.

entry is flagellar motor switch protein FliN. Authors conclude that H. pylori uses a FliY-FliN heterodimer instead of a homodimer and creates a switch complex with SpoA domains derived from three distinct proteins. (Mus musculus) PubMed

 22547.

Taken together, these data indicate that the viral uracil-DNA glycosylase (vUNG) and viral dUTPase (vDUT) coordinate to promote viral genomic stability and enable viral expansion prior to colonization of latent reservoirs.[vUNG, vDUT] (Mus musculus) PubMed

 22548.

Highly active recombinant botulinum neurotoxin type F light chain was purified and immune-characterized. Specific polyclonal antibodies generated against type F illustrates in vivo neutralization in mice and rabbit. [botulinum neurotoxin type F] (Mus musculus) PubMed

 22549.

TGB1 interacts directly with the glycine-arginine-rich (GAR) domain of the nucleolar protein fibrillarin.[TGB1] (Mus musculus) PubMed

 22550.

mycobacterial ClpC1 is subject to adaptor protein-mediated regulation in vitro.[ClpC1] (Mus musculus) PubMed

 22551.

simultaneous lack of the Pub1 and Upf1 proteins is lethal to cells harboring [PSI] variants with a strong, but not with a weak, suppressor phenotype.[Pub1, Upf1] (Mus musculus) PubMed

 22552.

MrrA serves as a central phosphorylation hub that coordinates the general stress response with C. crescentus development and other adaptive behaviors.[MrrA] (Mus musculus) PubMed

 22553.

FvCP01 (KatG1) and FvCP02 (KatG2) in the maize pathogen Fusarium verticillioides, were characterized.[FvCP01, FvCP02] (Mus musculus) PubMed

 22554.

the Myb-like transcription factor BasR is identified as the regulatory node for transduction of the bacterial signal in the fungus and show its function is conserved in other Aspergillus species.[BasR] (Mus musculus) PubMed

 22555.

These findings provide evidence that alpha-toxin (AT) plays a role in Staphylococcus aureus (SA) biofilm formation on epithelial surfaces and suggest that neutralization of AT may be useful in preventing and treating SA infections [alpha-toxin] (Mus musculus) PubMed

 22556.

Interaction between Neisseria gonorrhoeae bacterial peroxidase and its electron donor, the lipid-modified azurin [cytochrome c peroxidase] (Mus musculus) PubMed

 22557.

Study shows that APH-2 is covalently linked to SUMO moieties and addressed to PML nuclear bodies in all cell types tested inducing proteasomal degradation of the viral protein in a SUMO-dependent manner. Hence, APH-2 short half-life is controlled by its post-translational modifications and its subnuclear distribution. This might explain the decreased pathogenicity of HTLV-2 viral infection. [APH-2] (Mus musculus) PubMed

 22558.

AVR-Rmg8 was recognized not only by Rmg8, but also by Rmg7, suggesting that these two resistance genes are equivalent to a single gene from the viewpoint of resistance breeding.[Rmg7, Rmg8] (Mus musculus) PubMed

 22559.

AVR-Rmg8 was recognized not only by Rmg8, but also by Rmg7, suggesting that these two resistance genes are equivalent to a single gene from the viewpoint of resistance breeding.[AVR-Rmg8] (Mus musculus) PubMed

 22560.

First report on kinetic properties of recombinant beta- mannanase from Klebsiella oxytoca KUBCW2-3 expressed in E. coli. High specificity to konjac glucomannan is observed. [beta-mannanase] (Mus musculus) PubMed

 22561.

The molecular mass of the isolated enzyme, NADH-dependent diaphorase, was found to be about 50kDa, and determined to be a monomeric protein. The optimum pH and temperature for the catalytic activity of the enzyme was about pH 7.5 and 30 degrees C. The Km and Vmax values were estimated to be 0.025mM and 1.33mumol/min, respectively. [NADH-dependent diaphorase ] (Mus musculus) PubMed

 22562.

Cwp19 contributes to C. difficile cell autolysis in the stationary phase and toxin release. [Cwp19]] (Mus musculus) PubMed

 22563.

circzip-2 possibly sponges microRNA molecule miR-60 towards asserting an important role in various processes associated with Parkinson's disease.[circzip2] (Mus musculus) PubMed

 22564.

DcpA, a conserved, bifunctional protein with both DGC and PDE activities. A substrate-induced conformational switch involving movement of a loop containing a conserved motif in the bifunctional diguanylate cyclase-phosphodiesterase DcpA controls c-di-GMP turnover in M. smegmatis (Mus musculus) PubMed

 22565.

the role of bacterial expansins in plant diseases, the non-chimeric expansin genes (CmEXLX2 and RsEXLX) of two xylem-inhabiting bacterial pathogens, the Actinobacterium Clavibacter michiganensis ssp. michiganensis (Cmm) and the beta-proteobacterium Ralstonia solanacearum (Rs), respectively, were studied.[CmEXLX2] (Mus musculus) PubMed

 22566.

the crystal structures of a binary complex of the N-terminal catalytic SNL domain of SdcA with its cognate E2 UbcH5C and a ternary complex consisting of the SNL domain of SidC with the Ub-linked E2 UbcH7.[SidC] (Mus musculus) PubMed

 22567.

the role of bacterial expansins in plant diseases, we mutated the non-chimeric expansin genes (CmEXLX2 and RsEXLX) of two xylem-inhabiting bacterial pathogens, the Actinobacterium Clavibacter michiganensis ssp. michiganensis (Cmm) and the beta-proteobacterium Ralstonia solanacearum (Rs), respectively.[RsEXLX] (Mus musculus) PubMed

 22568.

structure and function of aIF1 [aIF1] (Mus musculus) PubMed

 22569.

ferroptosis is an ancient cell death program that can occur at individual subcellular membranes and is counterbalanced by evolutionary distant thiol peroxidases.[Tryparedoxin peroxidase] (Mus musculus) PubMed

 22570.

ScARP from the bacterium Streptomyces coelicolor belongs to the pierisin family of DNA-targeting ADP-ribosyltransferases (ARTs). Authors report the apo structure of ScARP and of ScARP bound to NADH and its GDP substrate at 1.50 and 1.57 A resolutions, respectively. (Mus musculus) PubMed

 22571.

Our results reveal that the yeast CaaX-type prenyltransferases can utilize a range of sequence combinations that extend beyond the traditional constraints for CaaX proteins, which implies that more proteins may be isoprenylated than previously considered. (Mus musculus) PubMed

 22572.

These findings suggest that FLO15 plays an important role in compound starch granule formation and starch synthesis in rice endosperm. [FLO15 ] (Mus musculus) PubMed

 22573.

Localization of palmitoylated and activated G protein alpha-subunit in Dictyostelium discoideum (Mus musculus) PubMed

 22574.

Metformin inhibits tumorigenesis in HBV-induced hepatocellular carcinoma by suppressing HULC overexpression caused by HBX. (Mus musculus) PubMed

 22575.

he present study demonstrated that Emuc can not only induce morphological change of adherent cells in vitro but also distinct cell and tissue damage and acute inflammation in mouse muscles, revealing and characterizing the Emuc pathogenicity both in vitro and in vivo. (Mus musculus) PubMed

 22576.

the roles of domains of MoPdeH and MoPdeL separately or in chimeras, were analyzed.[MoPdeH, MpPdeL] (Mus musculus) PubMed

 22577.

A thioredoxin domain-containing protein (TXND9) interacts with Pepino mosaic virus triple gene block protein 1 (TGBp1). [TGBp1] (Mus musculus) PubMed

 22578.

These results demonstrate that the streptococcal inhibitor of complement (SIC) interferes with coagulation and fibrinolysis and thereby enhances bacterial survival, a finding that has significant implications for S. pyogenes virulence. [ streptococcal inhibitor of complement] (Mus musculus) PubMed

 22579.

These results suggest an auxiliary binding role of the amidase domain of staphylococcal endolysins, which can be useful information for designing effective antimicrobial and diagnostic agents against S. aureus [amidase]. (Mus musculus) PubMed

 22580.

structure-based mutational analysis of GtgA uncovered amino acids that are required for the interaction of GtgA with p65, as well as those that are required for full activity of GtgA in suppressing NF-kappaB activation. (Mus musculus) PubMed

 22581.

upaE is an autotransporter gene that encodes a surface protein involved in adherence to extracellular matrix proteins and colonization of the kidneys [UpaE] (Mus musculus) PubMed

 22582.

KvrA and KvrB are regulators of virulence and contribute to capsule production [KvrA; KvrB] (Mus musculus) PubMed

 22583.

p25 of the dynactin complex plays a dual role in cargo binding and dynactin regulation.[p25] (Mus musculus) PubMed

 22584.

The N-terminal half of MDP1, homologous to bacterial histone-like protein HU, is predicted to be responsible for DNA-binding, while the C-terminal half is assumed as totally intrinsically disordered regions. [MDP1] (Mus musculus) PubMed

 22585.

Our studies provide evidence to suggest that nonstructural protein 8 (NSP8) serves as the N-terminal portion of nonstructural protein 9 [NSP8]. (Mus musculus) PubMed

 22586.

crystal structure of G. theta anion channelrhodopsin-1 at 2.9 A resolution [ACR1] (Mus musculus) PubMed

 22587.

We show that staphylococcal lipases SAL1 and SAL2, encoded by gehA and gehB, promote biofilm formation and host cell invasion and thereby contribute to S. aureus virulence. [gehA; gehB] (Mus musculus) PubMed

 22588.

This work highlights the importance of TgACBP2 (Acyl coenzyme A (CoA)-binding protein) in parasite cardiolipin metabolism and provides evidence for metabolic association of host mitochondria with T. gondii [ACBP2]. (Mus musculus) PubMed

 22589.

Herein, the authors identified a novel Coccidian Specific CORVET/HOPS Associated Protein (CSCHAP) belonging to the interaction network of both tethering complexes. Conditional depletion of CSCHAP leads to apical disconnection of rhoptries, aberrant apical organelles biogenesis and severely hinders Toxoplasma gondii invasion.[CSCHAP] (Mus musculus) PubMed

 22590.

B. thailandensis organic hydroperoxide reductase regulator (OhrR) has several unconventional features and that both OhrR and organic hydroperoxides may contribute to virulence [OhrR]. (Mus musculus) PubMed

 22591.

This work presents strong evidence supporting the role of PvMSP1P in host target cell selection and invasion of Duffy-independent pathway in P. vivax [MSP1P]. (Mus musculus) PubMed

 22592.

LvP5CDh plays a critical role in immune defense and antioxidant responses.[LvP5CDh] (Mus musculus) PubMed

 22593.

Genes regulated by T3 Receptor during intestinal metamorphosis. [T3 Receptor] (Mus musculus) PubMed

 22594.

PA25957 contains 432 amino acids with the presence of three structurally different domains: an N-terminal signal peptide, a C-terminal LPXTG motif.PA25957 is fibrinogen-binding protein.[PA25957] (Mus musculus) PubMed

 22595.

Together, these findings demonstrate that the outcome of gonococcal infection is determined by both the cell type-specific expression of human CEACAM1 and CEACAM5 and their specificity for the bacterial Opa variants expressed, which combine to determine the level of gonococcal association with the genital mucosa versus the extent of CEACAM-dependent inflammation and gonococcal clearance by neutrophils.[Opa] (Mus musculus) PubMed

 22596.

Interactions between CdrA and the exopolysaccharide Psl fortify the matrix by preventing CdrA proteolysis. When both components-CdrA and Psl-are part of the matrix, robust aggregates form that are tightly packed and protease resistant. [CdrA] (Mus musculus) PubMed

 22597.

This work demonstrates that S. aureus has developed tuning mechanisms, such as Fur regulation, to ensure that the cell has sufficient quantities of heme for efficient ATP production through aerobic respiration [Fur]. (Mus musculus) PubMed

 22598.

These results unambiguously demonstrate that IcsB is required for double-membrane vacuole escape during cell-to-cell spread, regardless of LC3 recruitment, and do not support the previously proposed notion that autophagy counters Shigella flexneri dissemination. (Mus musculus) PubMed

 22599.

Electrophoretic mobility shift assay showed that cyclic AMP receptor protein (CRP) can directly bind to the promoter of frwC. These results indicated that frwC expression is controlled by CRP directly and that such regulation contributes to bacterial growth, capsular polysaccharide synthesis, and virulence.[CRP, frwC] (Mus musculus) PubMed

 22600.

this could be attributed to the varied repair efficiencies of these lesions by O (6)-alkylguanine DNA alkyltransferase (MGMT) in cells, which involve the MGMT Ogt and, to a lesser extent, Ada. In conclusion, our study provides important new knowledge about the repair of the O (6)-alkyl-dG lesions and their recognition by the E. coli DNA replication machinery. (Mus musculus) PubMed

 22601.

Here, we generated crystal structures of HopQ isotypes I and II bound to the N-terminal domain of human CEACAM1 (C1ND) and elucidated the structural basis of H. pylori specificity toward human CEACAM receptors. Using SAXS, we show that the HopQ ectodomain is sufficient to induce C1ND monomerization and thus providing H. pylori a route to influence CEACAM-mediated cell adherence and signaling events. [HopQ] (Mus musculus) PubMed

 22602.

the role of ump2 in modulating transcription of key sets of genes (ump2) (Mus musculus) PubMed

 22603.

Modelling studies reveal conformational dynamics influence structure-function relationships of AlkB and FTO, e.g. why 1-methyladenine is a better substrate for AlkB than 6-methyladenine. [AlkB] (Mus musculus) PubMed

 22604.

structural and functional investigations of Nma111p, were performed.[Nma111] (Mus musculus) PubMed

 22605.

y4wF and tidC genes may have a role in synthesis of indole acetic acids (y4wF and tidC) (Mus musculus) PubMed

 22606.

Our results reveal that NS1' plays a vital role in blocking type I IFN production to help JEV evade antiviral immunity and benefit viral replication [NS1]. (Mus musculus) PubMed

 22607.

The duplication/insertion in Bm126 altered the viral expression pattern. [Bm126] (Mus musculus) PubMed

 22608.

This study reports the X-ray crystal structures of transcription complexes of the smallest and heterodimeric form of T7-like RNA polymerase (RNAP) , bacteriophage N4 RNA polymerase II, providing insights into the structural organization of a minimum RNAP in this family. [RNA polymerase II] (Mus musculus) PubMed

 22609.

The authors found that the aggregation-promoting factor APF-2 from these bacteria significantly contributes to inhibition of the adhesion of Trichomonas vaginalis to human vaginal ectocervical cells.[APF-2] (Mus musculus) PubMed

 22610.

he expression of the ampC gene increased by up to nine-fold in all eight exoU strains and the ampR was upregulated in seven exoU strains compared to PAO1. The expression of mexR gene was 1.4 to 3.6 fold lower in 75% of exoU strains. This study highlights the association between virulence traits and antibiotic resistance in pathogenic P. aeruginosa. (Mus musculus) PubMed

 22611.

the unique features of the OsPSTOL1 backcross inbred lines with bacterial blight and blast resistance can aid varietal development suitable for cultivation in Phosphorus deficient soils.[OsPSTOL1] (Mus musculus) PubMed

 22612.

Mutant pfdhps isolates also had increased gch1 copy number suggestive that it may also facilitate sulphadoxine resistance. The selection of parasites with pfgch1 gene amplification will enhance the sustenance and persistence of parasites with SP resistance in the country. Policy makers need to begin the search for a replacement chemoprophylaxis drug for malaria vulnerable groups in Ghana. (Mus musculus) PubMed

 22613.

Data demonstrate the requirement of TgFER2 for rhoptry secretion in Toxoplasma tachyzoites and suggest a possible Ca(2+) dependence of rhoptry secretion [FER2] . (Mus musculus) PubMed

 22614.

Data suggest that CcpA (conidial cell wall protein A) serves as a conidial stealth protein by altering the conidial surface structure to minimize innate immune recognition [CcpA]. (Mus musculus) PubMed

 22615.

These results therefore reveal an unexpected role of Kar1 in licensing meiotic spindle pole body duplication.[kar1] (Mus musculus) PubMed

 22616.

Tel1 has a high-affinity interaction with the C-terminus of Nbs1 and a low-affinity association with Mre11-Rad50, which together accomplish efficient localization and activation of Tel1 at double strand breaks and telomeres.[Tel1, Nbs1] (Mus musculus) PubMed

 22617.

candidate screen showed that among the selected motors only kinesin-8 motors Klp5/Klp6 are required for kinetochore centering.[Klp5, Klp6] (Mus musculus) PubMed

 22618.

a meiosis-specific cohesin complex with Rec8 controls nuclear envelope localization of Mps3.[Mps3, Rec8] (Mus musculus) PubMed

 22619.

This review explores the mechanism by which trigger factor actively guides folding by protecting partially folded states from distant interactions. [trigger factor] (Mus musculus) PubMed

 22620.

Our study delineates the role of beta2GPI in murine septicaemia though not in murine sepsis, however our preliminary patient data suggest that examining the role of beta2GPI in sepsis models in the future is a reasonable avenue to pursue. (Mus musculus) PubMed

 22621.

PtpA from Staphylococcus aureus contributes to virulence and interacts with coronin-1A during infection.[PtpA] (Mus musculus) PubMed

 22622.

Functional and biochemical studies with SinR variants revealed how these proteins allowed biofilm gene expression in the ymdB phosphodiesterase mutant strains [SinR]. (Mus musculus) PubMed

 22623.

d-2-Hydroxyglutarate dehydrogenase (D2HGDH) plays a dual role in l-serine biosynthesis and d-malate utilization in the bacterium Pseudomonas stutzeri. [D2HGDH] (Mus musculus) PubMed

 22624.

MYB3R is a positive transcription factor that enhances tolerance to drought and salt stress via an abscisic acid-dependent pathway.MYB3R is localised in the nucleus and possesses transcriptional activation activity (MYB3R). (Mus musculus) PubMed

 22625.

Thr166 is the most probable base abstracting proton from the Calpha atom of the substrate and Asp236 is crucial for binding of the cofactor to D-Serine deaminase (D-Serine deaminase). (Mus musculus) PubMed

 22626.

LepI is a novel multifunctional enzyme that catalyzes stereoselective dehydration, Diels-Alder reaction, and retro-Claisen rearrangement.This study reports the crystal structure of LepI in complex with its co-factor S-adenosyl methionine (SAM). LepI forms a tetramer via the N-terminal helical domain and binds to a SAM molecule in the C-terminal catalytic domain. [LepI] (Mus musculus) PubMed

 22627.

The deletion of amino acids 76 to 181 resulted in an unaltered regulation of Yop expression and secretion but triggered reduced YopE and YopH translocation within the first 30 min after infection.[YopN] (Mus musculus) PubMed

 22628.

Biochemical assays revealed a progressive increase in the hydrolysis rates from mannobiose to mannohexaose, which distinguishes XacMan2A from the known GH2 beta-mannosidases. [XacMan2A] (Mus musculus) PubMed

 22629.

Thus, in placental malaria+ women, antibodies to VAR2CSA were associated with lower placental parasitemias and reduced prevalence of low-birth-weight babies in this low-transmission setting [VAR2CSA]. (Mus musculus) PubMed

 22630.

The E. piscicida T3SS effector EseK promotes bacterial infection by inhibiting MAPK activation, which provides insights into the molecular pathogenesis of E. piscicida in fish [EseK]. (Mus musculus) PubMed

 22631.

The structure of Stu1-TOG2 reveals a CLASP-specific residue that likely confers distinctive tubulin-binding properties.[Stu1] (Mus musculus) PubMed

 22632.

the importance of the nonmotor tail in differentially controlling the physiological functions of the budding yeast kinesin-8, Kip3.[Kip3] (Mus musculus) PubMed

 22633.

Taken together, these data highlight the roles of O antigen length in generating phenotypes during Salmonella Typhimurium pathogenesis and show the role of Wzz copolymerase and the periplasmic protein VisP as a novel protein in the O antigen biosynthesis pathway.[Wzz, VisP] (Mus musculus) PubMed

 22634.

We show Extracellular adherence protein (Eap) subdomain Eap D3D4 specifically interacts and rapidly activates human platelets [Eap]. (Mus musculus) PubMed

 22635.

the PvHPPK-DHPS structure rationalizes and unravels the structural bases for SDX resistance mutations and highlights architectural features in HPPK-DHPSs from malaria parasites that can form the basis for developing next-generation anti-folate agents to combat malaria parasites. (Mus musculus) PubMed

 22636.

Ybt may provide access to nickel that is inaccessible to the conserved NikABCDE permease system. Nickel should be considered alongside iron and copper as a plausible substrate for Ybt-mediated metal import by enterobacteria during human infections. (Mus musculus) PubMed

 22637.

DHX9 enhanced NF-kappaB-dependent IL-6 promoter activation, which was directly antagonized by E3. These results indicate new roles for DHX9 in regulating cytokines in innate immunity and reveal that VACV E3 disrupts innate immune responses by targeting of DHX9. (Mus musculus) PubMed

 22638.

These results highlight a critical role for Aac2p transport in mitochondrial translation whose disturbance uniquely impacts cytochrome c oxidase.[Aac2, Cox3] (Mus musculus) PubMed

 22639.

Cdc42 exhibited reduced mobility at the cell pole, where it was organized in nanoclusters.[Cdc42] (Mus musculus) PubMed

 22640.

Sro7 tethering requires the presence of Sec4 on both opposing membranes and that homo-oligomerization of Sro7 occurs during vesicle tethering.[Sro7, Sec4] (Mus musculus) PubMed

 22641.

These results demonstrate that soybean GmTAP1 is a susceptibility factor that is hijacked by Phytophthora sojae PsAvh52 in order to promote epigenetic modifications that enhance the susceptibility of soybean to Phytophthora sojae infection.[PsAvh52] (Mus musculus) PubMed

 22642.

The 1.85-A-resolution crystal structure of allantoin synthase from the diatom Phaeodactylum tricornutum provides a rationale for the domain combinations observed in the metabolic pathway, suggesting that quaternary structure is key to the evolutionary success of protein domain fusions. [allantoin synthase ] (Mus musculus) PubMed

 22643.

While H3K36me deposited by SET-2 marks active genes, inactive genes are modified by ASH1 and its activity is critical for their repression. ASH1-marked chromatin can be further modified by methylation of H3K27, and ASH1 catalytic activity modulates the accumulation of H3K27me2/3 both positively and negatively.[ASH1] (Mus musculus) PubMed

 22644.

In this paper, using biolayer interferometry studies, the authors report that the multifunctional Streptococcus agalactiae GAPDH enzyme binds to a variety of host molecules such as PLG, Fg, laminin, transferrin and mucin with a KD value of 4.4x10(-7)M, 9.8x10(-7)M, 1x10(-5)M, 9.7x10(-12)M and 1.4x10(-7)M respectively.[GAPDH] (Mus musculus) PubMed

 22645.

HtrA degrades a number of proteins whose disappearance may help in preparing this organism for a stage of low metabolic activity.[HtrA] (Mus musculus) PubMed

 22646.

The similarity between apo and ligand-bound structures indicates that ligand-binding domains are strongly coupled to pore and SthK gates in an allosteric, concerted fashion. The different orientations of cAMP and cGMP in the 'resting' and 'activated' structures suggest a mechanism for ligand discrimination.[SthK] (Mus musculus) PubMed

 22647.

Further investigation into the mechanisms underlying shifts in regulator function for AmrZ could provide unique insights into the evolution of bacterial regulatory proteins [AmrZ]. (Mus musculus) PubMed

 22648.

Os10g34840 role in the cold tolerance.[Os10g34840] (Mus musculus) PubMed

 22649.

RNAi-mediated depletion of Trypanosoma brucei endonuclease V (TbEndoV) results in moderate growth defects in procyclic cells while the two TbEndoV alleles could be readily knocked out in bloodstream forms. Taken together, these observations suggest an important role of TbEndoV in RNA metabolism in procyclic forms of the parasite.[TbEndoV] (Mus musculus) PubMed

 22650.

These data suggest that p-mTOR and eIF4E expression is positively correlated with GS in canine PC, similar to the pattern in humans. More studies of the mTOR/4EBP1/eIF4E pathway should be performed to identify possible correlations of the proteins involved with clinical and pathologic findings in canine PC and the roles of these proteins as therapeutic targets for the treatment of canine PC. (Mus musculus) PubMed

 22651.

Major conformational changes in XaxB, including the swinging out of an amphipathic helix are responsible for membrane insertion. XaxA acts as an activator and stabilizer for XaxB that forms the actual transmembrane pore.[XaxA, XaxB] (Mus musculus) PubMed

 22652.

Observations indicate an adaptive role of Reverse Transcriptase A62V mutation in virus replication fidelity and viral fitness, which would likely enhance virus persistence during drug-selective pressure [Reverse transcriptase]. (Mus musculus) PubMed

 22653.

Knockdown of 74/86 (86%) TRP75 target proteins had a significant negative effect on ehrlichial infection [TRP75]. (Mus musculus) PubMed

 22654.

Thes results implicate carbonic anhydrase 1 and 2 -mediated signaling in the control of stomatal movement but not stomatal development (carbonic anhydrase 1 and carbonic anhydrase 2). (Mus musculus) PubMed

 22655.

regulates of compound leaf development - [CUP-SHAPED COTYLEDON/NO APICAL MERISTEM (CUC/NAM)] (Mus musculus) PubMed

 22656.

R545 is a key structural anchor in stabilizing the catalytic plugged-in conformation for target cleavage, whereas R486 is not involved in cleavage reaction [Argonaute] (Mus musculus) PubMed

 22657.

These data suggest that cglD in Escherichia coli E44 contributes to NF-kappaB pathway activation in the brain endothelium to promote polymorphonuclear leukocyte adhesion to human brain microvascular endothelial cells and transendothelial migration.[cglD] (Mus musculus) PubMed

 22658.

The role of phosphatidylinositol 3-kinase signaling in the energy and carbon metabolism.[phosphatidylinositol 3-kinase] (Mus musculus) PubMed

 22659.

These findings demonstrate that miR-219 inhibits TMEV-induced demyelinating disease through its anti-inflammatory and anti-viral properties. (Mus musculus) PubMed

 22660.

TlpQ has an unusually large dCACHE domain and binds histamine through a highly negatively charged pocket at its membrane distal module [TlpQ] (Mus musculus) PubMed

 22661.

We identified a PAS domain protein Pas3 that functions upstream of Znf2 in regulating cryptococcal filamentation. Pas3 interacts with the chromatin modifier Bre1 in the nucleus to regulate the transcript level of Znf2 and its prominent downstream targets. (Mus musculus) PubMed

 22662.

The structure of thermostable direct hemolysin-related hemolysin (TRH) was found to contain 19 pockets, of which one (pocket ID: 2) was predicted to be important from the view of drug design. Eleven residues (E138, Y140, C151, F158, C161, K162, S163, and Q164), which are reported to actively participate in the formation of the tetrameric structure, were present in this pocket.[TRH] (Mus musculus) PubMed

 22663.

CP (coat protein) and p6 showed suppressor activity, with CP showing significantly higher activity than p6, yet activity that was lower than the full OMMV, suggesting a complementary action of CP and p6 [CP]. (Mus musculus) PubMed

 22664.

SsaL interacted with SsaV in bacteria exposed to low ambient pH but not after the pH was raised to 7.2.[SsaL, SsaV] (Mus musculus) PubMed

 22665.

We show that GRA15, a Toxoplasma effector protein, suppresses the IFN-gamma-induced indole-2,3-dioxygenase 1-dependent antiparasite immune response in human cells [Gra15]. (Mus musculus) PubMed

 22666.

Mir156 role in the resistance to brown planthopper Nilaparvata lugens.[Mir156] (Mus musculus) PubMed

 22667.

cryo-electron microscopy captures a pilus assembly intermediate (FimD-FimC-FimF-FimG-FimH) in a conformation in which FimD is in the process of handing over the chaperone-bound end of the growing pilus to the C-terminal domains [fimD] (Mus musculus) PubMed

 22668.

DjlC and Flk are bona fide E. coli tail-anchored proteins. FtsY, DnaK and YidC Are Required for the Biogenesis of the E. coli Tail-Anchored Membrane Proteins DjlC and Flk. [DjlC, FtsY, DnaK, YidC, Flk] (Mus musculus) PubMed

 22669.

Orf24 and Orf91 encoded by the WSSV genome harbor a double zinc finger domain. [Orf24 and Orf91] (Mus musculus) PubMed

 22670.

The authors show that disruption of pre-18S rRNA processing via depletion of TbUTP10, results in the accumulation of rRNA precursors, a reduction of mature 18S rRNA, and also a decrease in the level of U3 snoRNA.[TbUTP10] (Mus musculus) PubMed

 22671.

LukF-I] Study identified 2 proteins, LukS-I and LukF-I, encoded on a degenerate prophage contained in the genome of S. pseudintermedius and describe a unique pore-forming toxin. Phylogenetic analysis showed LukS-I was most closely related to S. intermedius LukS-I, S. aureus LukE and LukP, whereas LukF-I was most similar to S. intermedius LukF-I S. aureus gamma hemolysin subunit B.[LukS-I and LukF-I] (Mus musculus) PubMed

 22672.

This study identifies CSE-7 as the putative ER receptor for its cognate cargo, the polytopic membrane protein CHS-4, and elucidates the complexity of the ER system in filamentous fungi. (Mus musculus) PubMed

 22673.

To elucidate how Zika virus protease (ZVP) affects host cellular pathways and consequent pathologies, the study used unbiased N-terminomics to identify 31 human proteins cleaved by the NS2B-NS3 protease. In particular, autophagy-related protein 16-1 (ATG16L1) and eukaryotic translation initiation factor 4 gamma 1 (eIF4G1) are dramatically depleted during Zika virus infection. [NS2B-NS3 protease] (Mus musculus) PubMed

 22674.

Sey1p requires additional factors to support efficient fusion in vivo. (Mus musculus) PubMed

 22675.

In the GLIC open conformation, E35 is connected through a water-mediated hydrogen-bond network first to the highly conserved electrostatic triad R192-D122-D32 and then to Y197-Y119-K248, both located at the extracellular domain-transmembrane domain interface. [GLIC] (Mus musculus) PubMed

 22676.

Sigma factor RpoD negatively regulates temperature-dependent metalloprotease expression in a pathogenic Vibrio splendidus.[Vibrio splendidus] (Mus musculus) PubMed

 22677.

the disordered C-terminal domain of RdRp was shown to be essential for binding to P10. [P10] (Mus musculus) PubMed

 22678.

The Km values for Coenzyme Q-1 (a benzoquinone, UQ-1) using recombinant MenJ from Mycobacterium smegmatis or M. tuberculosis without saturating concentrations of FAD were found to be 52 +/- 9.6 and 44 +/- 4.8 muM, respectively, while the Km(NADH) values were determined to be 59 +/- 14 and 64 +/- 15 muM. [MenJ] (Mus musculus) PubMed

 22679.

The Km values for Coenzyme Q-1 (a benzoquinone, UQ-1) using recombinant MenJ from Mycobacterium smegmatis or M. tuberculosis without saturating concentrations of FAD were found to be 52 +/- 9.6 and 44 +/- 4.8 muM, respectively, while the Km(NADH) values were determined to be 59 +/- 14 and 64 +/- 15 muM. [MenJ] (Mus musculus) PubMed

 22680.

We analyzed the dynamic localization and interaction of Chs3 and Chs4 during cell division, and found that both proteins transiently co-localize and physically interact only during bud formation and later in a period during septum formation and cytokinesis (Mus musculus) PubMed

 22681.

functions as an (S)-limonene synthase and plays a role in defence against Magnaporthe oryzae, at least partly by inhibiting spore germination [TPS19] (Mus musculus) PubMed

 22682.

E163 prevents the interaction of chemokines with cell-surface GAGs, providing mechanisms for the immunomodulatory activity of the viral chemokine-binding protein E163. (Mus musculus) PubMed

 22683.

Anthocyanin Acyltransferase1 (AAT1) is the first anthocyanin acyltransferase characterized in a monocot species and will increase our knowledge of all acyltransferase family members [AAT1] (Mus musculus) PubMed

 22684.

This study shows that isolated Type VI Secretion TssB Tail Sheath Subunit forms trimers, and reports the crystal structure of a C-terminal fragment of TssB. [TssB] (Mus musculus) PubMed

 22685.

Results show that PAF binds Ca2+ ions selectively at the C-terminus; however, this Ca2+ binding does not seem to play a direct role in the previously documented modulation of the antifungal activity of PAF. [PAF] (Mus musculus) PubMed

 22686.

Activity and stability of the alpha amylase were greatest at pH 7.0 and 45-55 degrees C. Na(+), Ca(2+), Mg(2+), Co(2+), Ba(2+), and K(+) increased activity, while Ni(2+), Hg(2+), Mn(2+), Cu(2+), Fe(3+), and Zn(2+) inhibited activity. [alpha amylase] (Mus musculus) PubMed

 22687.

a genome-wide approach was used to determine how RNase R and PNPase affect the mRNA half-lives in the stationary phase [PNPase]. (Mus musculus) PubMed

 22688.

These results support a role for k13 as a stress response regulator.[K13] (Mus musculus) PubMed

 22689.

these results suggest that the Rm3-dependent resistance relies mainly on the inducible expression of defence-related pathways and signalling elements within hours after the initiation of aphid feeding.[Rm3] (Mus musculus) PubMed

 22690.

food restriction-induced changes in motivation differ with stages of the estrous cycle and are closely linked to RFamide-related peptide-3 but not kisspeptin in Syrian hamsters [RFRP-3; kisspeptin] (Mus musculus) PubMed

 22691.

The host-Mycobacterium tuberculosis (Mtb) interaction map revealed two factors involved in Mtb pathogenesis-the secreted Mtb protein, LpqN, and its binding partner, the human ubiquitin ligase CBL. [LpqN] (Mus musculus) PubMed

 22692.

study is the first molecular characterization of LGDH, providing evidence for C3-specific oxidation and representing a starting point for future biotechnological use of LGDH and levoglucosan-metabolizing bacteria. (Mus musculus) PubMed

 22693.

CIF1 protein acts as a master regulator of cytokinesis by recruiting a cohort of cytokinesis regulatory proteins to the cytokinesis initiation site. (Mus musculus) PubMed

 22694.

CgC1qDC-7 was a novel PRR in C. gigas with high binding affinity towards LPS and PGN as well as Gram-negative bacteria. (Mus musculus) PubMed

 22695.

Higher levels of SaeRS-dependent virulence factors such as adhesins, toxins, and immune evasion proteins in the rho mutant resulted in higher virulence in a murine bacteremia model, which was alleviated in a rho complemented strain.[Rho, SaeR, SaeS] (Mus musculus) PubMed

 22696.

this study reveals attenuation of cAMP/CRP regulation as a relevant and RpoS-independent evolutionary route towards High hydrostatic pressure resistance in E. coli that coincides with fosfomycin resistance.[CRP, RpoS] (Mus musculus) PubMed

 22697.

The intracellular parasite Toxoplasma gondii harbors three druggable FNT-type formate and l-lactate transporters in the plasma membrane. (Mus musculus) PubMed

 22698.

Our data unraveled a previously unidentified mechanism through which Caspase 1-dependent cell death controlled virus infection in shrimp. (Mus musculus) PubMed

 22699.

VvMYBC2L2 plays a role as a negative regulator of anthocyanin biosynthesis.[VvMYBC2L2] (Mus musculus) PubMed

 22700.

It is suggested that OsNF-YC10 regulates the grains size and shape by influencing the cell proliferation of spikelet hulls. [NF-YC10] (Mus musculus) PubMed

 22701.

A green-revertible albino mutant gra78's albino phenotype at the early seedling stage was sensitive to temperature but independent of photoperiod. Map-based cloning revealed that candidate gene LOC_Os01g59920 of GRA78 encodes a putative S-sulfocysteine synthase showing significant similarity with Arabidopsis CS26. GRA78 is constitutively expressed in all tissues and its encoded protein is targeted to the chloroplast. (Mus musculus) PubMed

 22702.

The lytic transglycosylase MltB was identified as a critical fitness factor. MltB is part of a complex network connecting resistance to stresses, membrane homeostasis, biogenesis of pili and in vivo fitness. [MltB] (Mus musculus) PubMed

 22703.

when the same mild SMN missense mutations are expressed in a mouse containing two SMN2 copies, functional SMN complexes are formed with the small amount of wild-type FL-SMN produced by SMN2 and the SMA phenotype is completely rescued. This contrasts with SMN missense alleles when studied in C. elegans, Drosophila and zebrafish (Mus musculus) PubMed

 22704.

Structure of a C-S lyase Egt2 in ergothioneine synthesis pathway determined de novo. Cation-pi interactions were found to be critical for substrate specificity. Sulfenic acid intermediate was captioned at the active site in X-ray structure. [Egt2] (Mus musculus) PubMed

 22705.

Molecular characterization of neuropeptide elevenin and two elevenin receptors, ElevR1 and ElevR2, from the blacklegged tick, Ixodes scapularis, had been reported. [Elevenin], [ElevR1], [ElevR2] (Mus musculus) PubMed

 22706.

OsDOF11 Modulates Sugar Transport by Promoting Expression of Sucrose Transporter and SWEET Genes [DOF11] (Mus musculus) PubMed

 22707.

this study showed that conserved lysine residues in Central Cytoplasmic Loop (CCL) of the AstA protein may participate in anion selectivity, and control kinetic properties of the AstA transporter. [AstA] (Mus musculus) PubMed

 22708.

Atg8-binding regions in Hfl1 proteins adopt a helical conformation, thus representing a new type of Atg8-family-interacting motifs.[Atg8, Hfl1] (Mus musculus) PubMed

 22709.

Atg8-binding regions in Hfl1 proteins adopt a helical conformation, thus representing a new type of Atg8-family-interacting motifs.[Atg8, Hfl1] (Mus musculus) PubMed

 22710.

co-localized with chitin in the epidermal layer; emergence of the BmCBP1 signal in the new cuticle appeared slightly earlier than the chitin signal in the new cuticle [CBP1] (Mus musculus) PubMed

 22711.

Here, we report that overexpression of rice microRNA156 (OsmiR156) results in increased cell viability and growth rate under cold stress in Arabidopsis, pine, and rice. OsmiR156 increases cold stress tolerance by targeting OsSPL3 (Mus musculus) PubMed

 22712.

This study therefore provides a theoretical possibility for the application of TaHMA2 in transgenic breeding to regulate metal element balance in crop plants.[TaHMA2] (Mus musculus) PubMed

 22713.

M. xanthus expresses three enzymes, AdkA, AdkB, and Ppk1, with Adk activity, which may function to support energy metabolism of the bacteria in different environmental conditions. (Mus musculus) PubMed

 22714.

data uncovered a subset of T-lymphocytes expressing IL-37, which represents a potent regulation of immunity and serves as the protective role in chronic Inflammatory bowel disease. (Mus musculus) PubMed

 22715.

Data presents the molecular cloning and characterization of YqfO03, a new virulence factor in Pseudomonas syringae and shows that YqfO03 belongs to the Nif3-family protein with nematicidal activity against C. elegans and M. incognita. Furthermore, Purified YqfO03 protein causes reduced brood size, inhibits L1 growth, and causes abnormal locomotion of C. elegans. [YqfO03] (Mus musculus) PubMed

 22716.

structural analysis of CaHINT provided important insights into the molecular aspects of evolution within the histidine triad superfamily.[CaHINT] (Mus musculus) PubMed

 22717.

These experiments identify the first transcriptional regulator of O antigen chain length in Pseudomonas aeruginosa and support a model where transition to a chronic mucoid phenotype is correlated with downregulation of very long O antigen through decreased Wzz2 production.[Wzz2] (Mus musculus) PubMed

 22718.

Sfk1p negatively regulates transbilayer movement of phospholipids irrespective of directions.[Sfk1] (Mus musculus) PubMed

 22719.

The loss of function of both MtNOOT1 and MtNOOT2 resulted in the complete loss of nodule identity: [MtNOOT1 and MtNOOT2] (Mus musculus) PubMed

 22720.

These results suggest that control of the DNA sensing pathway by gamma134.5 is advantageous to herpes simplex virus 1 infection.[gamma134.5] (Mus musculus) PubMed

 22721.

This study revealed that antigenic site B of H3 hemagglutinin is immunodominant in the H3N2 influenza virus strain included in the current vaccine preparations.[H3 hemagglutinin] (Mus musculus) PubMed

 22722.

Cell morphology analysis indicated that the apical growth of hyphal cells was inhibited in Ras1-Cdc42-pathway deletion mutants. Thus, the control of cell polarity by the Ras1-Cdc42 pathway is crucial for hyphal development.[Ras1, Cdc42] (Mus musculus) PubMed

 22723.

The authors observed that the C-terminal modification of Pdr1 in an azole-resistant clinical isolate harboring a single GOF mutation, resulted in adverse effects such as decreased expression levels of Pdr1, downregulation of Pdr1 targets and azole hypersensitivity.[Pdr1] (Mus musculus) PubMed

 22724.

FMDV 2B negatively regulates the retinoic acid inducible gene-I like RNA helicases receptor-mediated IFN-beta induction by targeting RIG-I and MDA5 [NS2B] (Mus musculus) PubMed

 22725.

Erwinia ligand-gated ion channel (ELIC) is a bacterial homologue of vertebrate pentameric ligand-gated ion channels (pLGICs). In contrast to eukaryotic pLGICs, proline-to-alanine (Pro-to-Ala) substitution in ELIC mostly resulted in gain of function, and even altering highly conserved Pro residues in M1 and the M2-M3 loop did not ablate function. [ELIC] (Mus musculus) PubMed

 22726.

Expression pattern analysis showed that SiMYB42 was significantly up-regulated under various stress conditions, including low-nitrogen stress, high salt and drought. [MYB42] (Mus musculus) PubMed

 22727.

These results indicate that TaDrSR1 and TaDrSR2 potentially play vital roles in conferring drought tolerance in common wheat.[TaDrSR1, TaDrSR2] (Mus musculus) PubMed

 22728.

OsGPAT3 is proposed to coordinate the differentiation and degradation of the anther wall and pollen grains in addition to regulating lipid biosynthesis.[OsGPAT3] (Mus musculus) PubMed

 22729.

GhHB12, a cotton stress-responsive HD-ZIP I transcription factor, negatively regulates cotton resistance to V. dahlia.[GhHB12] (Mus musculus) PubMed

 22730.

sugar gustatory receptor that could accelerate the fecundity of BPH through AMPK- and AKT-mediated signaling pathways [Gr11] (Mus musculus) PubMed

 22731.

Rad52 is essential for protecting Rad51 filaments against dissociation by the Srs2 DNA translocase.[Rad52, Rad51, Srs2] (Mus musculus) PubMed

 22732.

In vivo, ShyB alone was sufficient to sustain cell growth in low-zinc environments. In vitro, ShyB retained its d,d-endopeptidase activity against purified sacculi in the presence of the metal chelator EDTA at concentrations that inhibit ShyA and ShyC. (Mus musculus) PubMed

 22733.

Further examination revealed that ectopic expression of the immediate early (IE) 86-kDa protein (IE86) of human cytomegalovirus is actually associated with a block in transcription of the pro-IL-1beta gene and, independently, diminishment of the immature protein.[IE86] (Mus musculus) PubMed

 22734.

Biochemical analyses showed that deletion of the KTR4 gene or the KTR7 gene leads to the absence of cell wall galactomannan.[KTR4, KTR7] (Mus musculus) PubMed

 22735.

Altogether, the findings support that Actinomyces oris LcpA is an archetypal LytR-CpsA-Psr family enzyme that glycosylates a cell wall-anchored protein, a process that may be conserved in Actinobacteria, given the conservation of LcpA and GspA in these high-GC-content organisms.[LcpA, GspA] (Mus musculus) PubMed

 22736.

Atg1 is present on autophagic puncta at, on average, twice the stoichiometry of Atg13.[Atg1, Atg13] (Mus musculus) PubMed

 22737.

In this work the specific activity of a nitrile reductase from Pectobacterium carotovorum was successfully increased from 354 to 526 U gprot(-1) by engineering the substrate binding pocket; moreover, the thermostability was also improved ( approximately 2-fold), showing half-lives of 140 and 32 h at 30 and 40 degrees C, respectively. [Nitrile Reductase] (Mus musculus) PubMed

 22738.

The presence of a transcription initiation site inside the open reading frame of UL24 and an ATG start codon in the same open reading frame led the authors to suspect that another protein was expressed from the UL24 locus. Western blot analysis revealed the expression of an 18-kDa protein that is not a degradation product of the full-length UL24, which they refer to as UL24.5.[UL24.5] (Mus musculus) PubMed

 22739.

Here the authors demonstrate that M16A-mutated RNA-dependent RNA polymerase 3D displays polymerase activity, RNA binding, and copying processivity that are similar to those of the wild-type enzyme but shows increased ribavirin-triphosphate incorporation.[3D] (Mus musculus) PubMed

 22740.

This study revealed that 4a-mediated inhibition of stress granule formation facilitates viral translation, leading to efficient Middle East respiratory syndrome coronavirus replication. (Mus musculus) PubMed

 22741.

RpoS regulates the expression of Vibrio vulnificus RtxA1 toxin and its transporter upon host contact. (Mus musculus) PubMed

 22742.

These results suggest that although Bm133 and Bm134 are not essential for budded virus or occlusion-derived virus development, they play vital roles in polyhedra morphogenesis. [bm133]. (Mus musculus) PubMed

 22743.

Substitution of T234 in CYP154F1 for large hydrophobic amino acids led to up to tenfold higher conversion rates of small substrates, such as geraniol. Replacement of T234 by small hydrophobic amino acids, valine or alanine, resulted in mutants with extended substrate spectra. These mutants are able to convert some of the larger substrates of CYP154E1, such as (E)-stilbene and (+)-nootkatone. [CYP154F1] (Mus musculus) PubMed

 22744.

Control of Grain Size and Weight by the OsMKKK10-OsMKK4-OsMAPK6 Signaling Pathway in Rice [MKKK10][MKKK4] (Mus musculus) PubMed

 22745.

Silencing of sucrose hydrolase (Suh) causes nymph mortality and disturbs adult osmotic homeostasis in Diaphorina citri. [Suh] (Mus musculus) PubMed

 22746.

We identified two 4.1B genes in zebrafish, 4.1Ba and 4.1Bb, by sequence comparisons and synteny analysis. In situ hybridization shows these genes are differentially expressed, with 4.1Ba expressed primarily in the nervous system and 4.1Bb expressed in the nervous system and muscle, but not the spinal cord. We focused our studies on 4.1Ba in the spinal cord. (Mus musculus) PubMed

 22747.

Hhp1/2 localize throughout the cell cycle to spindle pole bodies, as well as to the nucleus, cell tips, and division site.[Hhp1, Hhp2]] (Mus musculus) PubMed

 22748.

SMOC-1 acts as a positive modulator of BMP signaling. SMOC-1 functions cell nonautonomously to regulate body size. (Mus musculus) PubMed

 22749.

These findings suggest that pulse-dosing of butyrate slightly increased both GLP-1 and GLP-2 concentrations at specific time points and this might be promoted by direct or indirect effect of butyrate on the intestinal L-cells.[GLP 1, GLP 2] (Mus musculus) PubMed

 22750.

ZmmiR528 affects maize lodging resistance under N-luxury conditions [miR528] (Mus musculus) PubMed

 22751.

Zyxin has a scaffolding role in Gli1 and Zic1 interactions and in the regulation of Shh signaling cascade [Zyxin] (Mus musculus) PubMed

 22752.

Interaction of OsCML16 with OsPi304 indicates that they are involved in the cold stress signaling and response in rice. [OsCML16] (Mus musculus) PubMed

 22753.

lncRNA LINC00968 accelerates the proliferation and fibrosis of mesangial cells by epigenetically repressing p21 via recruiting EZH2 in diabetic nephropathy [LINC00968] (Mus musculus) PubMed

 22754.

the TORC1-Nem1/Spo7-Pah1 axis is a master regulator of not only macroautophagy but also microautophagy in budding yeast [TORC1] (Mus musculus) PubMed

 22755.

This study revealed, for the first time, a miR164-dependent regulatory pathway, miR164-NAC32/NAC40-EXPB14/EXPB15, which participates in maize seed expansion. These findings highlight the significance of miR164 in maize seed development, and can be used to explore the role of miRNA in seed development. (Mus musculus) PubMed

 22756.

Global nitrogen regulator GlnR interacts with the promoter regions beta-glucosidase-encoding genes. Deletion of glnR results in lower transcript levels and activity of beta-glucosidases, leading to decreased bacterial growth on cellulose. Overexpression of glnR or nitrogen starvation increases the transcript levels and total activity of beta-glucosidases. GlnR coordinates nitrogen metabolism and carbohydrate utilization. (Mus musculus) PubMed

 22757.

results demonstrate the structure, maturation process, inhibition, and substrate recognition of GAS ScpC, and reveal the presence of functional domains at the C-terminal region. (Mus musculus) PubMed

 22758.

Purified PfeE Esterase hydrolyzed ferri-Enterobactin (ENT) into three molecules of 2,3-DHBS (2,3-dihydroxybenzoylserine) still complexed with ferric iron, and complete dissociation of iron from ENT chelating groups was only possible in the presence of both PfeE and an iron reducer. [PfeE Esterase] (Mus musculus) PubMed

 22759.

This study determined the approximate g-tensor directions of the reduced Rieske-type [2Fe-2S](His)2(Cys)2 cluster in Rieske-type [2Fe-2S] ferredoxin (ARF) using (13)C Pulsed Electron Paramagnetic Resonance. [Rieske-type [2Fe-2S] ferredoxin] (Mus musculus) PubMed

 22760.

This study shows that beta-strand duplication in photoactive yellow protein (PYP), and the resulting possibility of beta-strand slippage, can lead to a new switchable protein-protein interaction. Beta - strand duplication may be a general means of introducing two-state switching activity into protein structures. [photoactive yellow protein] (Mus musculus) PubMed

 22761.

The study used site-directed mutagenesis to probe the roles of 13 conserved amino acids located on the flat substrate-binding surface of CBP21, a chitin-active family AA10 Lytic polysaccharide monooxygenases (LPMOs) from Serratia marcescens, also known as SmLPMO10A. [CBP21] (Mus musculus) PubMed

 22762.

This study reports biochemical and structural characterization of TtnD, a prenylated FMN (prFMN)-dependent decarboxylase belonging to the UbiD family that catalyzes the penultimate step of Tautomycetin biosynthesis. [TtnD] (Mus musculus) PubMed

 22763.

This study probed the interactions between YbdZ, and EntF, from Escherichia coli by performing a complete alanine scan of YbdZ. A phenotypic screen identified 11 YbdZ variants that are unable to replace the wild-type and these YbdZ variants were characterized using a series of in vivo and in vitro assays in an effort to explain why functional interactions with EntF were disrupted. [YbdZ, EntF] (Mus musculus) PubMed

 22764.

This study uncovers the Ptc2-Ssn3 axis as a new CO2 signaling pathway that controls hyphal elongation by regulating Ume6 stability in Candida albicans.[Ptc2, Ssn3, Ume6] (Mus musculus) PubMed

 22765.

Using an insertional mutagenesis approach, the current study identified the orphan histidine kinase CPR0195 as an important factor regulating Clostridium perfringens sporulation and Clostridium perfringens enterotoxin production.[CPR0195] (Mus musculus) PubMed

 22766.

Two DNA polymerases, PolB and PolD, from the hyperthermophilic archaeon Thermococcus kodakarensis interact directly with RPA in vitro. [PolB], [PolD] (Mus musculus) PubMed

 22767.

A TRIM71 binding long noncoding RNA Trincr1 represses FGF/ERK signaling in embryonic stem cells. [long noncoding RNA Trincr1] (Mus musculus) PubMed

 22768.

A TonB-dependent transporter is required for secretion of protease PopC across the bacterial outer membrane. [TonB], [PopC] (Mus musculus) PubMed

 22769.

The results point to BAFF as a main regulator of B cell homeostasis in the peritoneal cavity, suggesting that this cytokine can trigger different signals on different peritoneal B cell subsets in a specific manner (BAFF) (Mus musculus) PubMed

 22770.

Type VII secretion systems protein EssC variants (EssC1-EssC4) display sequence variability in the C-terminal region. The EssC2, EssC3 and EssC4 variants can be produced in a strain deleted for essC1, and that they are able to mediate secretion of EsxA, but unable to support secretion of the substrate protein EsxC, which is encoded in essC1-specific strains. (Mus musculus) PubMed

 22771.

The results indicated that SepF positively regulates the assembly of M. smegmatis FtsZ and the G51 residue has an important role in the functioning of SepF. (Mus musculus) PubMed

 22772.

we have utilized a biochemical characterizationapproach to understand the assembly of PTEX88 within PTEX across the asexual blood-stage life cycle. We provide evidence thatPTEX88 has the closestaffinity for HSP101but thatits interaction with the PTEX complex appears to be dynamic. (Mus musculus) PubMed

 22773.

Mechanism of ATP hydrolysis by the Zika virus helicase. (Mus musculus) PubMed

 22774.

LncRNA FOXC2-AS1 protects cardiomyocytes from doxorubicin-induced cardiotoxicity through activation of Wisp1. [LncRNA FOXC2-AS1] (Mus musculus) PubMed

 22775.

Multiple copies of small regulatory RNA (sRNA), Esr41 abolishe the locus of enterocyte effacement (LEE) expression and reduces Enterohaemorrhagic Escherichia coli (EHEC) adhesion to host cells. Esr41 activates the expression of flagellar Class 3 genes by indirectly inducing the transcription of the sigma factor for flagellar synthesis. Esr41 plays important roles in inverse regulation of LEE and flagellar gene expression. (Mus musculus) PubMed

 22776.

Study reports the structure of human adenovirus type 3 fibre knob (HAd3K) in complex with one and two molecules of the DSG2 receptor. (fibre knob) (Mus musculus) PubMed

 22777.

Here the authors describe a manganese exporter in Staphylococcus aureus, MntE, which is a member of the cation diffusion facilitator (CDF) protein family and conserved among Gram-positive pathogens. Upregulation of mntE transcription in response to excess manganese is dependent on the presence of MntR, a transcriptional repressor of the mntABC manganese uptake system.[MntE] (Mus musculus) PubMed

 22778.

The results demonstrate the ability of CYP267B1 to perform in-chain hydroxylations of medium-chain saturated fatty acids (decanoic acid, dodecanoic acid and tetradecanoic acid) and a regioselective hydroxylation of flavanone. The fatty acids are mono-hydroxylated at different in-chain positions, with decanoic acid displaying the highest regioselectivity towards omega-3 hydroxylation. (Mus musculus) PubMed

 22779.

These findings together reveal unique roles of Hippo-LATS-YAP signaling in the developing mouse lung.[Hippo] (Mus musculus) PubMed

 22780.

Functional annotation of putative fadE9 of Mycobacterium tuberculosis as isobutyryl-CoA dehydrogenase involved in valine catabolism [fadE9] (Mus musculus) PubMed

 22781.

Bacillus subtilis ATP-dependent proteases ClpYQ deletion mutants form early and robust biofilms, while swarming motility is impaired. Colonies of the clpYQ deletion mutant are less mucoid, indicating the decreased secretion of gamma-poly-dl-glutamic acid (gamma-PGA). Proteomic analysis confirms that proteins involved in motility, chemotaxis, the production of gamma-PGA and biofilm master repressor SinR are less abundant. (Mus musculus) PubMed

 22782.

SIX1a is required for full virulence of Fusarium oxysporum f.sp. cubense TR4 towards Cavendish banana [SIX1a] (Mus musculus) PubMed

 22783.

Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism. (Mus musculus) PubMed

 22784.

Teg41 is positively influencing cytolytic alpha phenol-soluble modulin (alphaPSM) production, demonstrating for the first time regulation of the alphaPSM peptides by a small RNA in Staphylococcus aureus.[Teg41, alphaPSM] (Mus musculus) PubMed

 22785.

The structure of the large extracellular loop 1 of FtsX reveals an upper extended beta-hairpin and a lower alpha-helical lobe, each extending from a mixed alpha-beta core. The helical lobe mediates a physical interaction with the peptidoglycan hydrolase PcsB via the coiled-coil domain of PcsB.[FtsX, PcsB] (Mus musculus) PubMed

 22786.

Here the authors used ChIP-seq coupled with RNA-seq to define the BldC regulon in the model species Streptomyces venezuelae, showing that BldC can function both as a repressor and as an activator of transcription.[BldC] (Mus musculus) PubMed

 22787.

Spt23 is responsible for regulation of Delta-9 desaturase expression in Pichia pastoris. Our results give new insights into the relationship between Spt23 and high temperature environmental stress [Spt23]. (Mus musculus) PubMed

 22788.

Guarding the gateway to histidine biosynthesis in plants: Medicago truncatula ATP-phosphoribosyltransferase in relaxed and tense states. (Mus musculus) PubMed

 22789.

Taken together, these results suggest that A. fumigatus independently regulates iron and copper homeostasis in a manner that involves AfMac1 and mutual interactions. (Mus musculus) PubMed

 22790.

This study shows that the hydrolytic activity of a bacterial Cu(I)-transporting P-type ATPase (LpCopA) is stimulated by the bacterial, anionic phospholipid cardiolipin and to some extent by phosphatidylglycerol. [Cu(I)-transporting P-type ATPase] (Mus musculus) PubMed

 22791.

Phenotypic analyses of knockout mutants and hydroxybenzoate uptake assays provide compelling evidence that the permeases Hbt1 and Hbt2 transport the substrates that are metabolized via the gentisate (3-hydroxybenzoate, gentisate) and 3-oxoadipate pathway (4-hydroxybenzoate, 2,4-dihydroxybenzoate and protocatechuate), respectively.[Hbt1, Hbt2] (Mus musculus) PubMed

 22792.

We describe for the first-time from India, insertional inactivation of mgrB by ISKpn14 inserted at different sites, responsible for colistin resistance (Mus musculus) PubMed

 22793.

Overproduction of the dimer form results in filamentation, suggesting that MipZ dimers are regulating FtsZ activity and thus septation.[MipZ] (Mus musculus) PubMed

 22794.

Taken together, the data determined in the study reveal a novel immunosuppressive strategy of Staphylococcus aureus whereby the bacterium blunts the development of adaptive immunity via LukAB-mediated injury of dendritic cells.[LukAB] (Mus musculus) PubMed

 22795.

The authors found that expression of CHK1, another effector kinase involved in the DNA damage response, is regulated by Rad53 and that CHK1 deletion rendered cells highly susceptible to DNA damage stress.[CHK1, Rad53] (Mus musculus) PubMed

 22796.

The RabX6 is involved in the regulation of testicular growth and male-specific neuropeptide secretion in the brain of Bombyx mori (RabX6). (Mus musculus) PubMed

 22797.

The findings indicate that the Saccharomyces cerevisiae Mim1/Mim2 and the Trypanosoma brucei pATOM36 are the products of convergent evolution and arose only after the ancestors of fungi and trypanosomatids diverged. [pATOM36] (Mus musculus) PubMed

 22798.

To increase transglycosylation activity in two family 18 chitinases, chitinase D from Serratia proteamaculans ( SpChiD) and chitinase A from Serratia marcescens ( SmChiA), this study introduced mutated residues important for stabilizing the reaction intermediate and substrate binding in both donor and acceptor sites. [chitinase A] (Mus musculus) PubMed

 22799.

Initial velocity patterns, isothermal titration calorimetry, and differential scanning fluorimetry establish a distinct kinetic mechanism for ATP phosphoribosyltransferase (ATPPRT) where 5-phospho-alpha-d-ribosyl-1-pyrophosphate is the first substrate to bind. AMP is an inhibitor of HisGS, but steady-state kinetics and (31)P NMR spectroscopy demonstrate that ADP is an alternative substrate. [ATP phosphoribosyltransfera... (Mus musculus) PubMed

 22800.

To increase transglycosylation activity in two family 18 chitinases, chitinase D from Serratia proteamaculans ( SpChiD) and chitinase A from Serratia marcescens ( SmChiA), this study introduced mutated residues important for stabilizing the reaction intermediate and substrate binding in both donor and acceptor sites. [chitinase D] (Mus musculus) PubMed

 22801.

The data are suggesting a previously undescribed role for Shiga toxin-producing Escherichia coli Shiga toxins in suppressing host immune responses during Shiga toxin-producing Escherichia coli infection and survival.[Stx2a, Stx2c] (Mus musculus) PubMed

 22802.

proposed that DltD uses a catalytic dyad to transfer d-alanine to LTA. [DltD] (Mus musculus) PubMed

 22803.

Electrostatic interactions between middle domain motif-1 and the AAA1 module of the bacterial ClpB chaperone are essential for protein disaggregation [ClpB] (Mus musculus) PubMed

 22804.

Binding of a physiological substrate causes large-scale conformational reorganization in cytochrome P450 51 [CYP51] (Mus musculus) PubMed

 22805.

Crystal structure of the bacterial acetate transporter SatP reveals that it forms a hexameric channel [SatP} (Mus musculus) PubMed

 22806.

functions as an adaptor between HD-ZIP III and CsWUS transcription factors regulating anther and ovule development - [SPL] (Mus musculus) PubMed

 22807.

Role of latency associated protein Acr-1 in differential modulation of macrophages [Acr-1] (Mus musculus) PubMed

 22808.

The N-terminal approximately 80 residues of the nuclease colicin ColE9 are intrinsically unstructured and house two OmpF binding sites (OBS1 and OBS2) that reside within the pores of OmpF and which flank an epitope that binds periplasmic TolB. [OmpF] (Mus musculus) PubMed

 22809.

Distinct properties underlie flavin-based electron bifurcation in a novel electron transfer flavoprotein FixAB from Rhodopseudomonas palustris. (Mus musculus) PubMed

 22810.

We show that the K. pneumoniae TolC complements the efflux defect in an E. coli K-12 DeltatolC strain, restoring wild-type levels of resistance towards most antibiotics suggesting that it can interact with the E. coli AcrB efflux pump [TolC]. (Mus musculus) PubMed

 22811.

Acting as a sensor of the cellular energy status, Slr2111 regulates chromophorylation of cyanobacteriochrome Slr1393 via allosteric interaction. It possesses a cystathionine beta-synthase domain pair.[Slr1393] (Mus musculus) PubMed

 22812.

the interactions between PafE and the proteasome core particle that cause conformational changes leading to the opening of the proteasome gate and have uncovered a mechanism of PafE-mediated substrate degradation. (Mus musculus) PubMed

 22813.

role of an endoreduplication-related gene in response to drought stress - [TOP6B] (Mus musculus) PubMed

 22814.

This study suggests that RSV nonstructural protein 1 (NS1) interacts with TRIM25 and interferes with RIG-I ubiquitination to suppress type-I interferon signaling [NS1]. (Mus musculus) PubMed

 22815.

We determined that the P6 protein could interact with the cell translation initiation factor FveIF3g of Fragaria vesca and co-localize with it in the nuclei of Nicotiana benthamiana cells [P6 protein]. (Mus musculus) PubMed

 22816.

Results demonstrate that secreted MIP-3beta and its effect on the JNK signaling pathways mediates dengue virus-induced BV2 microglial cell migration [MIP-3beta]. (Mus musculus) PubMed

 22817.

FBK1 plays a role in the development of rice anthers and roots by regulating the cellular levels of a key enzyme controlling lignification.[FBK1] Cinnamoyl-CoA Reductase turnover is regulated by FBK1.[Cinnamoyl-CoA Reductase] (Mus musculus) PubMed

 22818.

Molecular characterization of the interaction of sialic acid with the periplasmic binding protein from Haemophilus ducreyi. (Mus musculus) PubMed

 22819.

Together, these findings suggest that CpxR negatively regulates xcnA-L genes expression while positively regulating xcnMN expression in Xenorhabdus nematophila YL001, which led to a high yield of xenocoumacin 1 in DeltacpxR mutant.[CpxR] (Mus musculus) PubMed

 22820.

Structural and molecular dynamics studies of a C1-oxidizing lytic polysaccharide monooxygenase from Heterobasidion irregulare reveal amino acids important for substrate recognition. [LPMO9B] (Mus musculus) PubMed

 22821.

Data suggest that wild-type LACK orchestrates robust LmCOX4 expression and mitochondrial fitness to ensure parasite virulence, via optimized functional interactions with the ribosome [Cox4]. (Mus musculus) PubMed

 22822.

S9C subfamily member from Deinococcus radiodurans, in its active and inactive states at 2.3-A resolution, providing an unprecedented view of assembly and disassembly of the active site mediated by an arginine residue. (Mus musculus) PubMed

 22823.

PMEI3 enhances resistance to Verticillium wilt (PMEI3). (Mus musculus) PubMed

 22824.

global Nodal inhibition maintains the left bias of Spaw activity, demonstrating conservation between zebrafish and mouse mechanisms of left-right patterning.[Nodal] (Mus musculus) PubMed

 22825.

Mice infected with mutants deficient in SpsL or both SpsD and SpsL developed larger cutaneous lesions with distinct histopathological features of regionally extensive cellulitis rather than focal abscessation. Furthermore, comparison of the bacterial loads in S. pseudintermedius-induced cutaneous lesions revealed a significantly increased burden of bacteria in the mice infected with SpsL-deficient mutants.[SpsL] (Mus musculus) PubMed

 22826.

The authors screened 927 seeds from 70 Ac/Ds plants for salinity tolerance and identified one activation-tagged salt tolerant DS plant (DS-16, T3 generation) that showed enhanced expression of a novel 'histone-like transcription factor' belonging to rice NF-Y subfamily C and was named as OsNF-YC13. (Mus musculus) PubMed

 22827.

increase in benznidazole and nifurtimox susceptibility in TcOYE overexpressing parasites showed its participation in activating the currently anti-chagasic drugs, which added to its observed ability to confer resistance to hydrogen peroxide, highlights the relevance of this enzyme in multiple events including host-parasite interaction. (Mus musculus) PubMed

 22828.

Here, the authors show that PspC is a pneumococcal plasminogen receptor and that plasmin generated on the surface of hemolytic uremic syndrome pneumococci damages endothelial cells, causing endothelial retraction and exposure of the underlying matrix.[PspC] (Mus musculus) PubMed

 22829.

Here we report that the phosphorylation of Cth2 at specific serine residues is essential to regulate the stability of the protein and adaptation to iron depletion [Cth2]. (Mus musculus) PubMed

 22830.

contributes to activate plant immune response to the fungal pathogen Botryosphaeria dothidea - [PUB29] (Mus musculus) PubMed

 22831.

The tetrameric structure of PaTagF comprises varied N- and C-terminal regions in each subunit and may be stabilized by a symmetry-related molecule. This feature was also shown in the TssL structure from V. cholerae. (Mus musculus) PubMed

 22832.

Together, these results demonstrate that PpiB contributes to Staphylococcus aureus virulence via a mechanism unrelated to prolyl isomerase activity. (Mus musculus) PubMed

 22833.

findings indicate a plasticity, within otherwise conserved modes of AdoCbl binding, oligomerization, operator design, and DNA binding, which underlies the action of a B12-based CarH photoreceptor in light-dependent gene expression. (Mus musculus) PubMed

 22834.

Study identified a novel transcription factor FgSR and its cis-element regulating ergosterol biosynthesis in F. graminearum. The phosphorylation of FgSR by MAP kinase FgHog1 regulates its transcriptional activity and its interaction with the SWI/SNF complex. In addition, FgSR also functions in virulence by modulating deoxynivalenol biosynthesis, and fungal responses to phytoalexins and DNA damage. (FgSR) (Mus musculus) PubMed

 22835.

Pgrl1 role in the electron transport and photosynthesis.[PGRL1] (Mus musculus) PubMed

 22836.

A primary role of MATE67 in citrate efflux from nodule cells in response to an Fe signal.MATE67 is an Fe-activated citrate transporter.MATE67-mediated citrate transport into the symbiosome space would increase the solubility and availability of Fe(III) for rhizobial bacteroids. [MATE67] (Mus musculus) PubMed

 22837.

Wpropose that PtsH contributes to root colonization of B. cereus 905 through multiple indistinct mechanisms [PtsH]. (Mus musculus) PubMed

 22838.

The structure of PilA from Acinetobacter baumannii AB5075 suggests a mechanism for functional specialization in Acinetobacter type IV pili. (Mus musculus) PubMed

 22839.

We discovered a novel catalase (STM14_2049, Cat) whose expression is strictly concentration-dependent. The purified Cat protein has obvious catalase activity in vitro and in vivo and can restore the growth of the low concentration oxyR mutant strain [catalase]. (Mus musculus) PubMed

 22840.

ERF17 has been under selection since the origin of apple tree cultivation.Natural variation in the coding region of the ERF17 contributes to apple (Malus domestica) fruit peel degreening. [ERF17] (Mus musculus) PubMed

 22841.

STK protein directly phosphorylates threonine at amino acid position 199 (Thr-199) of DivIVA. [ DivIVA] (Mus musculus) PubMed

 22842.

The CTPS gene is essential for parasite survival. [CTPS] (Mus musculus) PubMed

 22843.

Here, the authors identify candidalysin, a peptide derived from the hypha-specific ECE1 gene, as a fungal trigger for Nlrp3 inflammasome-mediated maturation and secretion of IL-1beta from primary macrophages.[ECE1] (Mus musculus) PubMed

 22844.

The data suggest that GRA35, GRA42, and GRA43 Toxoplasma dense granule proteins play a critical role in establishing a chronic infection in vivo, independently of their role in mediating macrophage pyroptosis, likely due to their importance in regulating protein localization to the parasitophorous vacuole membrane.[GRA35, GRA42, GRA43] (Mus musculus) PubMed

 22845.

results imply that BfmR plays a role in controlling stress responses in A. baumannii which help protect cells during desiccation, and they provide a regulatory link between this organism's ability to persist in the environment and pathogenicity [BfmR] (Mus musculus) PubMed

 22846.

The rocA deletion mutant strain had significantly increased secreted activity of multiple virulence factors and grew to significantly higher colony counts under acid stress in vitro RocA inactivation also significantly increased group A streptococcus virulence in a mouse model of necrotizing myositis.[rocA] (Mus musculus) PubMed

 22847.

The authors report that PrpA is S-palmitoylated in two N-terminal cysteine residues by the host cell and that this modification is necessary for its biological activity. The results demonstrate that S-palmitoylation promotes PrpA migration to the host cell plasma membrane and stabilizes the protein during infection.[PrpA] (Mus musculus) PubMed

 22848.

The authors found that deletion of estH significantly diminished cyclic GMP (cGMP) activation in target epithelia, while deletion of estP had a surprisingly modest impact, and a dual estH estP mutant was not appreciably different from the estH mutant. They also found that the TolC efflux protein was essential for toxin secretion and delivery.[estH, estP, TolC] (Mus musculus) PubMed

 22849.

VraSR appears to have an accessory role other than sensing membrane damage in daptomycin-resistant strains [VraSR]. (Mus musculus) PubMed

 22850.

S. aureus (SauCas9) and especially S. pyogenes (SpyCas9) are among the best-characterized Cas9 proteins and share approximately 17% sequence identity. In contrast to SpyCas9, SauCas9 is a multiple-turnover enzyme, which to our knowledge is the first report of such activity in a Cas9 homolog. DNA cleaved with SauCas9 does not undergo any detectable single-stranded degradation after the initial double-stranded break. (Cas9) (Mus musculus) PubMed

 22851.

increases biomass and grain yield - [VIL2] (Mus musculus) PubMed

 22852.

NF-kappaB activation was a major contributor to Porcine transmissible gastroenteritis virus infection-induced inflammation, and nonstructural protein 2 (Nsp2) was the key viral protein involved in the regulation of inflammation, with amino acids 1-120 playing a critical role in activating NF-kappaB [Nsp2]. (Mus musculus) PubMed

 22853.

PhoPR played roles in orchestrating Pi acquisition as well as transporter-independent mechanisms that contribute to S. aureus virulence. [PhoP. PhoR] (Mus musculus) PubMed

 22854.

NanR null mutant displayed much less sporulation and enterotoxin production but more NanI production.[NanR] (Mus musculus) PubMed

 22855.

Structural and kinetic characterization of (S)-1-amino-2-propanol kinase [(S)-1-amino-2-propanol kinase] (Mus musculus) PubMed

 22856.

MrpJ contributes to P. mirabilis pathogenesis, leading to the discovery of novel virulence targets. [MrpJ] (Mus musculus) PubMed

 22857.

In conclusion, Protein A is a determinant for (neutrophil extracellular traps) NETosis induction by S. aureus. (Mus musculus) PubMed

 22858.

Zaxinone synthase expression and role in zaxinone biosynthesis.[zaxinone synthase] (Mus musculus) PubMed

 22859.

WzmWzt ABC transporter protein conformation shows interaction with lipids and explains crucial role in transporter gating. [WzmWzt ABC transporter] (Mus musculus) PubMed

 22860.

PDEB1 is needed for transition to the ectoperitrophic space of tsetse flies.[PDEB1] (Mus musculus) PubMed

 22861.

FTL9 role in the flowering transition under different day lengths.[FTL9] (Mus musculus) PubMed

 22862.

overexpression in transgenic creeping bentgrass results in altered development and improved multiple stress tolerance - [miR393a] (Mus musculus) PubMed

 22863.

the sugar beet Rf1 locus has a series of multiple alleles that differ in their ability to restore fertility and are reflective of the complexity of Rf evolution [Rf1] (Mus musculus) PubMed

 22864.

Study demonstrated that Clostridium perfringens NetF protein is a pore-forming toxin and is able to form large, oligomeric pores on cell membranes. Although NetF probably has a common structure organization with other members of beta-pore-forming toxins, its cellular receptor is still unclear and remains to be determined. (NetF) (Mus musculus) PubMed

 22865.

This study suggests an evolutionary mechanism for PKC-theta; unique V3 and reveals BbPKC-delta/theta; is the common ancestor of PKC-delta and -theta; with a functional proto-V3 domain, supplying new evidence for the existence of primitive adaptive immune system in amphioxus.[PKC-delta/theta;] (Mus musculus) PubMed

 22866.

a functional annotation of boAP3D1 cellular adaptor protein and BLV gp51, is reported.[gp51] (Mus musculus) PubMed

 22867.

Reduction in plant height with Rht8 and Rht1 averaged 2.86% and 13.3% respectively as compared to the group of lines lacking dwarfing gene.[Rht8] (Mus musculus) PubMed

 22868.

S. suis synthesizes 2'-deoxyadenosine and adenosine by 5'-nucleotidase to dampen host immune responses, which represents a new mechanism of S. suis pathogenesis [5'-nucleotidase]. (Mus musculus) PubMed

 22869.

candidate combox site 4 (Ccs4) contributes to pneumococcal invasion of host brain tissues and functions as a virulence factor [Ccs4] (Mus musculus) PubMed

 22870.

Pneumococcal neuraminidase A induces platelet desialylation. (Mus musculus) PubMed

 22871.

EspH to be an effector that prompts the recruitment of the tetraspanin CD81 to infection sites. (Mus musculus) PubMed

 22872.

The HD-ZIP III transcription factor CsPHB is an important player in the modulation of leaf shape development in cucumber. [PHB] (Mus musculus) PubMed

 22873.

S. aureus CRB has at least two PBP4-mediated resistance mechanisms [PBP4] (Mus musculus) PubMed

 22874.

CaKR1 is involved in capsaicinoid biosynthesis and that its disruption results in a loss of pungency. [CaKR1] (Mus musculus) PubMed

 22875.

A new Bacillus thuringiensis gene Vip3Aa65 has been isolated and the activity of the encoded protein was tested against five lepidopteran pests. The combined insecticidal activity of the crystal and supernatant fraction containing the Vip3Aa protein makes these isolates promising candidates for the development of new biopesticides. (Vip3Aa65) (Mus musculus) PubMed

 22876.

The RAMD simulations on product-bound structures of both ttTMPK and hTMPK, revealed that while several exit patterns of the products are permissible, the sequential exit mode is the most preferred pattern for both ttTMPK and hTMPK enzymes. Additionally, the product release from the hTMPK was found to be faster and more directional as compared to ttTMPK (Mus musculus) PubMed

 22877.

MAVA5_06970 is a key virulence effector of M. avium that contributes to the cell-to-cell spread of the pathogen. [MAVA5_06970] (Mus musculus) PubMed

 22878.

The transcription factor CsMYB36 can regulate the yellow green peel coloration in cucumber. [CsMYB36] (Mus musculus) PubMed

 22879.

ICP6 impedes the translocation of RIPK1, RIPK3, and MLKL to caveolin-1-containing DRM vesicles without fully blocking the activation of RIPK3 or phosphorylation of MLKL. (Mus musculus) PubMed

 22880.

affects cell fate specification by regulating GhPIN1-mediated auxin distribution - [L1L1] (Mus musculus) PubMed

 22881.

mediates signaling from both bacterial surfaces and diffusible chemoattractants to reorganize actin for chemotaxis and phagocytosis; extracellular Venus-Flytrap domain acts as the binding site for both folate and lipopolysaccharide [far1] (Mus musculus) PubMed

 22882.

Overexpression promotes lignin biosynthesis and stomatal closure that improves drought tolerance - [TF1L] (Mus musculus) PubMed

 22883.

autoreactive anti-ENO1 (alpha-enolase)/mEno1 antibodies that are produced as byproducts during the antibody response to TdEno play a minimal role in the progression of periodontitis in the absence of rheumatoid arthritis [alpha-enolase]. (Mus musculus) PubMed

 22884.

Our data indicate a direct effect of alpha-2,3-sialyltransferase gene (lsgB) on lipooligosaccharide sialylation and reveal important roles of lsgB in promoting the pathogenicity of H. parasuis [lsgB]. (Mus musculus) PubMed

 22885.

PilR is a transcriptional regulator involved in the expression of a wide variety of genes, including pilA (pilus structural protein) relevant c-type cytochromes and some other genes involved in biofilm formation.These findings suggest that PilR-deficient mutant forms a thinner and less conductive biofilm than wild type, exhibiting different and irreversible redox processes at the interface (CV analysis). [PilR, pilA] (Mus musculus) PubMed

 22886.

LptE depletion only marginally affects LPS localization and maturation. LptE appears to be crucial for LptD biogenesis and/or stability. [LptE] (Mus musculus) PubMed

 22887.

residues contributing to the activity and substrate specificity of Fm1 [Fm1] (Mus musculus) PubMed

 22888.

NB gene plays crucial roles in regulating the determinacy of shoots. The NB gene was mainly expressed in the root and shoot apex, and expression rhythms were also observed in these tissues, suggesting that the expression of the NB gene could be regulated by photoperiod. [NB} (Mus musculus) PubMed

 22889.

extreme C terminus of the Pseudomonas aeruginosa effector ExoY is crucial for binding to its eukaryotic activator, F-actin [ExoY] (Mus musculus) PubMed

 22890.

stat5bl was predominantly expressed in immune tissues, where the highest level was observed in liver, followed by skin and gill. stat5bl could be up-regulated by Vibrio harveyi infection in all tissues except liver, despite the timepoints of peak were different.[stat5bl] (Mus musculus) PubMed

 22891.

The expression level of CsRac1 and CsRac2 fluctuated in the liver and gill tissues at different time points after challenged by Vibrio harveyi. Specifically, CsRac1 and CsRac2 were significantly up-regulated at 48h and 96h post injection. Moreover, the knocking down of CsRac1 and CsRac2 in cell line (TSHKC) reduced the expression of CsPAK1, CsIL1-beta and CsTNF-alpha.[rac1] (Mus musculus) PubMed

 22892.

Results indicate that Phosphatidate phosphatase is involved in triacylglycerol biosynthesis during lipogenesis in Y. lipolytica [Phosphatidate phosphatase]. (Mus musculus) PubMed

 22893.

Serum-induced activation of vncRS operon plays an essential role in inducing pneumonia [vncRS]. (Mus musculus) PubMed

 22894.

Peroxiredoxin 5 prevents iron overload-induced neuronal death by inhibiting mitochondrial fragmentation and endoplasmic reticulum stress in mouse hippocampal HT-22 cells (Mus musculus) PubMed

 22895.

We conclude that unprocessed R-loops collapse replication forks in rnh1 rnh201 cells, but RNase H is not generally required for efficient double-strand break repair [RnaseH]. (Mus musculus) PubMed

 22896.

promotes fruit tubercule formation - [Tu-TS1] (Mus musculus) PubMed

 22897.

structural information of the interaction of Zika capsid protein with lipid droplets and binding capacity to RNA and DNA (capsid protein) (Mus musculus) PubMed

 22898.

the mitochondrial ThPP transporter TptA promotes low iron adaptation and virulence in A. fumigatus [TptA] (Mus musculus) PubMed

 22899.

Our work identified a F. tularensis protein, ArfT, that rescues stalled ribosomes in the absence of trans-translation using a new mechanism. [ArfT] (Mus musculus) PubMed

 22900.

The daptomycin resistance mechanism is highly specific and relies on a different process that involves a functional MprF flippase [MprF]. (Mus musculus) PubMed

 22901.

CpaA increases the clotting time in the activated partial thromboplastin time assay through proteolytic cleavage and inactivation of fXII in both human and murine plasma. Specifically, CpaA targets the glycosylated, proline-rich domain of fXII. [CpaA] (Mus musculus) PubMed

 22902.

This work shows that protein arginine methyltransferase (PRMT1) itself binds nucleic acids in vitro and in vivo, a feature completely novel to protein arginine methyltransferases. [PRMT]. (Mus musculus) PubMed

 22903.

RpoQ is a strong repressor of rugose colony morphology and biofilm formation, and that it controls motility of the bacteria. [RpoQ] (Mus musculus) PubMed

 22904.

Data show that Cdc48-like protein of actinobacteria (Cpa) forms hexameric rings and that the oligomeric state correlates directly with the ATPase activity; the assembled Cpa rings can physically interact with the 20S core particle. Comparison of the Mycobacterium smegmatis wild-type with a cpa knockout strain under carbon starvation uncovers significant changes in the levels of around 500 proteins. [Cpa] (Mus musculus) PubMed

 22905.

Inclusion bodies presumably composed of the enzyme attached to native Cry1A crystals of recombinant strains were observed; these inclusions were likely responsible for the enhancements in chitinase activity (Mus musculus) PubMed

 22906.

HAMP motions to the histidine kinase function of CpxA [CpxA] (Mus musculus) PubMed

 22907.

Two or more baseline NS5A resistance-associated substitutions were found in nearly 5% of all patients and were significantly associated to direct acting antiviral failure. [NS5A]. (Mus musculus) PubMed

 22908.

These data suggest that accumulated phosphorylated CpxR (CpxR~P) inversely manipulates the levels of two global transcriptional regulators, RovA and RovM, and this would be expected to have considerable influence on Yersinia pathophysiology and metabolism [CpxxR] . (Mus musculus) PubMed

 22909.

the dynamic regulation of the T. brucei transferrin receptor in response to iron starvation is mediated via its 3'UTR, and that the effect is independent of genomic location. (Mus musculus) PubMed

 22910.

ERAdP-mediated production of pro-inflammatory cytokines is critical for controlling bacterial infection (Mus musculus) PubMed

 22911.

PARG may possess endo-glycohydrolase activity toward poly-ADP-ribose (PAR). [PARG] (Mus musculus) PubMed

 22912.

Trypanosoma cruzi AUK1 also seems to play a role during the initiation of kinetoplast duplication, a novel role described for this protein. [AUK1] (Mus musculus) PubMed

 22913.

These results demonstrate the potential role for the ABC transporter CD2068 in the resistance mechanism against multiple drugs in Clostridium difficile. (Mus musculus) PubMed

 22914.

Ribosomes accumulated at start codons, were depleted from stop codons, and showed codon-specific changes in occupancy in lso2Delta.[Lso2] (Mus musculus) PubMed

 22915.

PKAc1 sensitises parasites to cyclic GMP (cGMP)-induced Ca2+ signalling, thus demonstrating a functional link between cAMP and these other signalling modalities.[PKAc1] (Mus musculus) PubMed

 22916.

the structure and function of Vip3Aa protein [Vip3Aa] (Mus musculus) PubMed

 22917.

The coil-coiled domain of DIP0733 is crucial for interaction with epithelial cells and pathogenicity. [DIP0733] (Mus musculus) PubMed

 22918.

In this study, we identified and characterized a prominent 15-kilodalton protein, LTRIN, obtained from the salivary glands of the mosquito Aedes aegypti. LTRIN expression was upregulated in blood-fed mosquitoes, and LTRIN facilitated the transmission of Zika virus (ZIKV) and exacerbated its pathogenicity (Mus musculus) PubMed

 22919.

These results suggest a mechanism whereby DHS negatively regulates wax biosynthesis by promoting the degradation of ROC4.[DHS] (Mus musculus) PubMed

 22920.

Both the unique amino acid residues and 3D structure of the 4a-NS5B may influence both genotype 4a replication rate and response to therapy in comparison to other genotypes [NS5B] (Mus musculus) PubMed

 22921.

A critical role for miR166 in cadmium accumulation and tolerance through regulation of its target gene HB4.[miR166] (Mus musculus) PubMed

 22922.

Here we report that C. neoformans chitin deacetylases Cda1 is the principal Cda responsible for fungal pathogenesis [Cda1]. (Mus musculus) PubMed

 22923.

These results strengthen the role of caveolae in insulin signaling and help to explain adipocyte response to hypoxia.[Insulin] (Mus musculus) PubMed

 22924.

RpfC positively regulates the expression of hrpX independent of RpfG, showing a complex regulatory network linking the rpf/DSF and hrp/T3SS systems. [RpfC, hrpX] (Mus musculus) PubMed

 22925.

A novel mechanism of inactivating antibacterial nitro compounds in the human pathogen Staphylococcus aureus by overexpression of a NADH-Dependent flavin nitroreductase, SAUSA300_0859. [SAUSA300_0859] (Mus musculus) PubMed

 22926.

TLP12 is a chemoreceptor for glutamate and pyruvate recognition.[Tlp12] (Mus musculus) PubMed

 22927.

IPSE/alpha-1 (here M-IPSE), a major protein secreted from S. mansoni eggs, can infiltrate host cells [IPSE/alpha-1]. (Mus musculus) PubMed

 22928.

CP16160 and CP14019 showed similar substrate specificity, while CP16779 has a slightly different substrate specificity.[CP16160, CP14019, CP16779] (Mus musculus) PubMed

 22929.

The interaction between PILNCR1 and miR399 is important for tolerance to low phosphate in maize.[PILNCR1][miR399] (Mus musculus) PubMed

 22930.

The lactonization process of Cl-cis,cis-muconate catalyzed by muconate lactonizing enzyme was studied theoretically with the aid of a combined quantum mechanics/molecular mechanics (QM/MM) approach. The present work provided the explicit structures of the enolate anion intermediates. [muconate lactonizing enzyme] (Mus musculus) PubMed

 22931.

Dissemination of multidrug-resistant Proteus mirabilis clones carrying a novel integron-borne blaIMP-1 in a tertiary Brazilian hospital has been reported. [IMP-1] (Mus musculus) PubMed

 22932.

OsMGT1 plays an important role in rice Magnesium (Mg) import and is required for the resistance to Mg deficiency.[OsMGT1] (Mus musculus) PubMed

 22933.

The CarS RING finger protein down-regulates many genes whose expression is up-regulated by light, indicating a regulatory interplay between the mechanism of action of the CarS protein and the control by light (CarS). (Mus musculus) PubMed

 22934.

the functions of the domains of BPH14 were analyzed to identify molecular mechanisms underpinning BPH14-mediated planthopper resistance.[BPH14] (Mus musculus) PubMed

 22935.

On the basis of the obtained results, we indicated that Vp26 acts as the elicitor of hypersensitive response-like reactions of PVX-Vp26 manifesting with enhanced pathogenicity of the recombined PVX [Vp26]. (Mus musculus) PubMed

 22936.

The authors identified a CLASP1/CD2AP/EB1-containing protein complex that surrounds the Theileria annulata schizont throughout the host cell cycle. This complex also includes the schizont membrane protein Ta-p104 together with a novel secreted Theileria annulata protein (encoded by TA20980), which they term microtubule and SH3 domain-interacting protein (TaMISHIP).[TaMISHIP] (Mus musculus) PubMed

 22937.

Although NSP3 and NSP5 are ER transmembrane proteins, these proteins did not activate the ER stress signaling pathways. In addition, the cytoplasmic domain of NSP3 plays a pivotal role in activating autophagy [NSP3]. (Mus musculus) PubMed

 22938.

TgCep530 is a large coiled-coil protein with an essential role in the survival of the parasite. Depletion of this protein leads to the accumulation of parasites lacking nuclei and disruption of the normal cell cycle. Lack of TgCep530 results in a discoordination between the nuclear cycle and the budding cycle that yields fully formed parasites without nuclei.[TgCep530] (Mus musculus) PubMed

 22939.

Collectively, these in vivo findings identify NanI sialidase (NanI) to be the first known significant contributor to chronic intestinal colonization by nonfoodborne strains [NanI sialidase]. (Mus musculus) PubMed

 22940.

On PfRecQ1 deletion, the upsC1 var gene moved from the active perinuclear transcription region to a silenced region of the upsC type. These findings imply that PfRecQ1, but not PfWRN, is essential for maintaining the clonal expression of var genes (Mus musculus) PubMed

 22941.

On PfRecQ1 deletion, the upsC1 var gene moved from the active perinuclear transcription region to a silenced region of the upsC type. These findings imply that PfRecQ1, but not PfWRN, is essential for maintaining the clonal expression of var genes (Mus musculus) PubMed

 22942.

this study described a new MCR-1 variant (MCR-1.9) in an E. coli from a swine, among Enterobacteriaceae isolates from food-producing animals, meat, meat products and animal feed, screened for the detection of plasmid-mediated colistin resistance. [MCR-1.9] (Mus musculus) PubMed

 22943.

These results strongly support that protozoan proteins RON2 and RN4 and host protein CD71 participate in Plasmodium vivax's complex invasion process, thus providing new pertinent targets for blocking P. vivax merozoites' specific entry to their target cells.[RON2, RON4] (Mus musculus) PubMed

 22944.

Sterol profiling of CYP710C1 overexpressing L. donovani and heterozygous mutant parasites demonstrated that CYP710C1 was responsible for stigmasterol production. These CYP710C1 overexpressing promastigotes are resistant to amphotericin B [CYP710C1]. (Mus musculus) PubMed

 22945.

The protein YlBud8 of Yarrowia lipolytica shares amino acid sequence homology with Saccharomyces cerevisiae Bud8, and a conserved transmembrane domain at the C-terminus. Deletion of YlBud8 in Y. lipolytica causes cellular separation defects, resulting in budded cells remaining linked with one another as cell chains or multiple buds from a single cell, suggestsing that YlBud8 play an important role in cell separation. (Mus musculus) PubMed

 22946.

This study reveals a switchlike role for FoxA in regulating WCP4 expression and provides new insights into the regulatory regulation of wing disc development in insects. [FoxA] (Mus musculus) PubMed

 22947.

The authors cloned and expressed the naphthalene catabolic genes, tested them for Cr (VI) reduction, and found that NahG reduced 79% of 100 muM Cr (VI) in 5 minutes. Additionally, a nahG deletion mutant lost 52% of its Cr (VI) reduction ability compared to that of the wild-type strain.[nahG] (Mus musculus) PubMed

 22948.

A cobalamin-specific ECF-type ABC transporter from Lactobacillus delbrueckii, ECF-CbrT, has been characterized and demonstrated that it mediates the specific, ATP-dependent uptake of cobalamin. [ECF-CvrT] (Mus musculus) PubMed

 22949.

EarP is a novel inverting glycosyltransferase with a role in protein arginine rhamnosylation (Mus musculus) PubMed

 22950.

CT143 protein could stimulate the secretion of inflammatory cytokines in macrophages which differentiated from THP-1 This induction may be mediated by the activation of p38 signaling. In summary, CT143 protein is involved in inflammatory processes during Ct infection. (Mus musculus) PubMed

 22951.

the Toh1(20-365)-YFP hybrid protein fluorescent aggregates are co-localized with a high frequency with Rnq1C-CFP and Sup35NM-CFP aggregates in the yeast cells containing [PIN(+)] and [PSI(+)] prions.[Toh1, Rnq1, Sup35] (Mus musculus) PubMed

 22952.

[TATA box-binding protein-associated factor 1 (TAF1)] identified the TBP-associated factor 1 (Ehtaf1) gene in the E. histolytica genome, which possess a well-conserved DUF domain and a Bromo domain located in the middle and C-terminus of the protein, respectively and is expressed in the nucleus and cytoplasm at 37 degrees C, but under heat shock stress, it is overexpressed in both the nucleus and cytoplasm (Mus musculus) PubMed

 22953.

PknG plays an important regulatory role in mycobacterial metabolism, through phosphorylation of ATP binding proteins and enzymes in the TCA cycle.[PknG] (Mus musculus) PubMed

 22954.

The M-domain jumps are much faster than the overall activity of ClpB, making it an effectively continuous, tunable switch.[ClpB] (Mus musculus) PubMed

 22955.

Autoinducer 2 (AI-2) promotes Nontypeable Haemophilus influenzae biofilm maturation and the maintenance of biofilm integrity, due at least in part to the expression of a probable glycosyltransferase that is potentially involved in the synthesis of the biofilm matrix [Autoinducer 2]. (Mus musculus) PubMed

 22956.

In this study, we characterized the dose effects of "X" genes on flagellar gene expression and cross talk between focX and papX We found that both FocX and PapX repress flhD transcription. [FocX; PapX] (Mus musculus) PubMed

 22957.

Five lines of evidence support the conclusion that movement of the bPBP2x:FtsW complex in septa depends on peptidoglycan (PG) synthesis and not on FtsZ treadmilling. (Mus musculus) PubMed

 22958.

Zika viral titer in the HPX8C-depleted mosquitoes decreased significantly. The level of HPX8c affects both dengue virus and Zika virus levels, indicating that the role of HPX8C is universal [HPX8C] (Mus musculus) PubMed

 22959.

This is the first functional report of TrxH in fish pathogens, and the findings suggest that TrxHEp is essential for coping with adverse circumstances and contributes to host infection of E. piscicida.[TrxH] (Mus musculus) PubMed

 22960.

Avian viral polymerase from A/duck/Pennsylvania/ 10,218/84 (DkPen) enhances the viral polymerase activity in mammalian cells by replacing the PA or PB2 gene with that from human influenza virus A/WSN/33 (WSN). The N-terminal endonuclease domain of WSN PA is essential for the mammalian adaptation of DkPen viral polymerase. The activity of viral genome replication may be enhanced in the DkPen reassortant containing WSN PA. (Mus musculus) PubMed

 22961.

These results show that Trp171 and several glutamate residues in the constriction region are key for the transport of glucose, the preferred natural substrate, through OprB. [OprB] (Mus musculus) PubMed

 22962.

This study for the first time characterizes a pyruvate transporter in E. coli, BtsT, as a specific pyruvate/H(+) symporter.[BtsT] (Mus musculus) PubMed

 22963.

a change in plasma membrane sterol homeostasis promotes cell survival under membrane-perturbing conditions known to activate TORC2-Ypk1 signaling.[Ypk1] (Mus musculus) PubMed

 22964.

An H. somni mutant lacking IbpA, but not the DR1/DR2 region within ibpA, was more susceptible to killing by antiserum than the parent, indicating that the entire protein was associated with serum resistance. [IbpA] (Mus musculus) PubMed

 22965.

Four hit compounds that inhibit T. cruzi SpdSyn were identified by in silico and in vitro screening. SpdSyn-hit compound complex structure using X-ray crystallography was determined: the hit compound binds to the putrescine-binding site and interacts with Asp171 through a salt bridge. (gene: spermidine synthase) (Mus musculus) PubMed

 22966.

Mycobacterium avium subspecies paratuberculosis MDH is a novel immunostimulatory antigen that drives Th1-biased T cell polarization via interactions with dendritic cells.[MDH] (Mus musculus) PubMed

 22967.

SpeG as a modulator of E. coli transcription through its ability to interact with the transcription factor RcsB [SpeG] (Mus musculus) PubMed

 22968.

The present study predicted the potential functions of sex-biased miRNA and indicated that miR-1388 regulates cell junctions by inhibiting nectin2l, which may have an important role in the later development of testes. [miR-1388] (Mus musculus) PubMed

 22969.

ESAT6 might contribute to virulence of M. tuberculosis by regulating type I IFNs production through TLR4-TRIF signaling pathway.[ESAT6] (Mus musculus) PubMed

 22970.

DnfD functions in a trafficking process that is specifically required for the morphological changes that take place during conidiation [DnfD]. (Mus musculus) PubMed

 22971.

histidine kinase (cheA) is the most functional interaction partner with virulence factor aerolysin [cheA] (Mus musculus) PubMed

 22972.

Deletion found in the MS-H oppF gene causes truncation of OppF in this vaccine strain. The indirect ELISA based on OppF-C has the potential to differentiate between MS-H and field strain antibody responses. [OppF]. (Mus musculus) PubMed

 22973.

Our results demonstrated that R. anatipestifer gene AS87_08785 encoded a component of the type IX secretion system, GldK, which functioned in bacterial gliding motility, protein secretion, and bacterial virulence [GldK]. (Mus musculus) PubMed

 22974.

The authors demonstrated that a majority of cholera toxin is secreted in its outer membrane vesicle-associated form and is located exclusively inside the vesicle. Therefore, the toxin is unable to bind GM1 ganglioside on the host cell surface, and the outer membrane vesicles are trafficked to the host cells in a GM1-independent mechanism.[cholera toxin] (Mus musculus) PubMed

 22975.

FdhC from Bacillus thuringiensis is a functional formate transporter. [FdhC] (Mus musculus) PubMed

 22976.

LotA exhibits a dual ability to cleave ubiquitin chains that is dependent on 2 distinctive catalytic cysteine residues in the eukaryotic ovarian tumour domains.[LotA] (Mus musculus) PubMed

 22977.

The uncovered ability for Hos2 to directly deacetylate H4-K16 and to indirectly modify H3-K56, H2A-S129, and CDK1-Y15 provides novel insight into more subtle regulatory role for Hos2 in genomic stability and diverse cellular events in the fungal insect pathogen than those revealed previously in nonentomophathogenic fungi.[Hos2, Histone H2] (Mus musculus) PubMed

 22978.

processes nsp1, nsp2, and nsp3 from the replicase polyprotein [PLpro (papain-like protease)] (Mus musculus) PubMed

 22979.

proteolytically resistant core structure of SARS coronavirus S2 fusion protein [S2 protein] (Mus musculus) PubMed

 22980.

3a protein localized mainly in Golgi complex; contained three transmembrane regions, second & third regions responsible for Golgi localization; an integral membrane protein; co-localized with M protein along the Golgi complex [3a] (Mus musculus) PubMed

 22981.

structural similarities to herpesvirus-associated ubiquitin-specific protease suggest that, in addition to polyprotein processing activity, PLpro might possess deubiquitinating activity [papain-like protease, PLpro] (Mus musculus) PubMed

 22982.

Results provide insights into the maturation process of the SARS 3CL(pro) from the polyprotein and design of new structure-based inhibitors [3CL protease]. (Mus musculus) PubMed

 22983.

both the C- and the N-terminal regions influence the dimerization and enzyme activity of the SARS-CoV main protease [main protease] (Mus musculus) PubMed

 22984.

S protein, produced in transgenic plants, might be considered as a viral vaccine. (Mus musculus) PubMed

 22985.

3a protein expressed in the lungs and intestinal tissues of SARS patients, localized to the endoplasmic reticulum in 3a-transfected monkey kidney Vero E6 cells, and can induce apoptosis in Vero cells [3a] (Mus musculus) PubMed

 22986.

it was shown that 3b protein was predominately localized to the nucleus; a region (residues 134-154 aa) responsible for nucleolar localization was determined [3b nonstructural protein] (Mus musculus) PubMed

 22987.

Through cell cycle analysis, it was found that over-expression of 3b-EGFP protein in Vero, 293 and COS-7 cells could induce cell cycle arrest at G0/G1 phase.[3b] (Mus musculus) PubMed

 22988.

SARS-CoV non-structural protein 10 (nsp10) interacts specifically with the NADH 4L subunit and cytochrome oxidase II [nsp10] (Mus musculus) PubMed

 22989.

crystal structure of unbound M(pro)revealed that N-terminal residues 1 to 7 of both protomers are well defined and the substrate-binding regions of both protomers are in the catalytically competent conformation at crystallization pH of 6.5(main peptidase) (Mus musculus) PubMed

 22990.

The vacuolar-H+ ATPase (V-ATPase) G1 subunit that contained a 3CL(pro) cleavage site-like motif was identified as a CoV 3CL(pro)-interacting protein.(CoV 3CL(pro)) (Mus musculus) PubMed

 22991.

assessed conformational flexibility of M(pro) by analysis of crystal structures & molecular dynamics calculations; MD simulations take into account protonation states of 2 histidine residues in substrate-binding site & explain pH-activity profile [M(pro)] (Mus musculus) PubMed

 22992.

the majority of the dimerization-critical residues plus Ser284-Thr285-Ile286 and Phe291 are clustered together to form a nano-scale channel passing through the central region of the enzyme (3C-like protease) (Mus musculus) PubMed

 22993.

A sole requirement of hepta- and octo-uridine as signals for efficient frameshifting during expression of ORF 3a variants (ORF 3a). (Mus musculus) PubMed

 22994.

the SARS coronavirus main proteinase is an active C2 crystallographic dimer (Mus musculus) PubMed

 22995.

identifies an RNA virus exoribonuclease activity that is involved in the synthesis of multiple RNAs from the exceptionally large genomic RNA templates of coronavirus [exoribonuclease] (Mus musculus) PubMed

 22996.

SARS 3C-like proteinase may follow the association, activation, catalysis, and dissociation mechanism for activity control [SARS 3C-like proteinase] (Mus musculus) PubMed

 22997.

Structure and xray crystalography of (papain-like protease) (Mus musculus) PubMed

 22998.

The SARS-CoV nsp3 gene region corresponding to amino acids 182-355 has been cloned, expressed in Escherichia coli, purified and crystallized Sars Covnsp3 productP (Mus musculus) PubMed

 22999.

SARS full-length Nsp15 (346 amino acids) has been cloned and expressed in Escherichia coli with an N-terminal hexahistidine tag and has been purified to homogeneity. (NSP15) (Mus musculus) PubMed

 23000.

Enzyme activity from the SARS CoV main proteinase dimer could readily be detected at low pM concentrations [3C-like proteinase] (Mus musculus) PubMed

 23001.

Data show that SARS-CoV 3b fused with EGFP at its N- or C- terminus co-localized with a mitochondria-specific marker in some transfected cells [3b protein]. (Mus musculus) PubMed

 23002.

Confocal microscopy results indicated that SARS 8b is localized in both nucleus and cytoplasm of mammalian cells [8b protein] (Mus musculus) PubMed

 23003.

The crystal structure of ORF-9b was reported (ORF-9b) (Mus musculus) PubMed

 23004.

The crystal structure of SARS-CoV nsp10 at a resolution of 1.8 A as determined by single-wavelength anomalous dispersion using phases derived from hexatantalum dodecabromide was reported.(nsp10) (Mus musculus) PubMed

 23005.

The crystal structure of nsp10 from SARS-CoV at 2.1-A resolution was reported.(nsp10) (Mus musculus) PubMed

 23006.

mechanistic determinants of SARS coronavirus nonstructural protein 15 show that it is critically involved in the coronavirus replication cycle (Mus musculus) PubMed

 23007.

coronavirus nsp1-mediated promotion of host mRNA degradation may play an important role in coronavirus pathogenesis[nsp1] (Mus musculus) PubMed

 23008.

Our results showed that Vero E6 cells transfected with a construct for expressing 3b protein underwent necrosis as early as 6h after transfection and underwent simultaneous necrosis and apoptosis at later time-points. [3b protein] (Mus musculus) PubMed

 23009.

absence of a major neutralizing domain on S2 protein[S sars1] (Mus musculus) PubMed

 23010.

The SARS coronavirus nonstructural protein 1(nsp-1) plays an important role in CCL5, CXCL10, and CCL3 expression in human lung epithelial cells via the activation of NF-kappaB. [nsp-1] (Mus musculus) PubMed

 23011.

analysis of the enzyme machinery of SARS coronavirus replicase (review) [replicase] (Mus musculus) PubMed

 23012.

analysis of SARS-CoV papain-like protease deubiquitinating activity (Mus musculus) PubMed

 23013.

nsp2 proteins of mouse hepatitis virus and SARS coronavirus are not critical for viral replication [nsp2] (Mus musculus) PubMed

 23014.

analysis of a frameshifting signal in SARS-CoV ORF3a (Mus musculus) PubMed

 23015.

analysis of ADP-ribose-1"-phosphatase activities of the human coronavirus 229E and SARS coronavirus X domains, contained in nsp3 [nsp3] (Mus musculus) PubMed

 23016.

ORF3b, ORF6 and N proteins inhibit the synthesis of IFNbeta and function of IRF3, and N protein inhibits the function of NF-kb. {ORF3b, ORF6, N protein] (Mus musculus) PubMed

 23017.

The SARS coronavirus main proteinaseis required for the replication of the severe acute respiratory syndrome coronavirus that causes the syndrome [Coronavirus main proteinase] (Mus musculus) PubMed

 23018.

structure is analyzed in a search for possible correlations with the recently reported activity of nsp1 in the degradation of mRNA[nonstructural protein 1] (Mus musculus) PubMed

 23019.

the crystal structure of a monomeric form of nsp15 suggests a role for hexamerization as an allosteric switch [nsp15] (Mus musculus) PubMed

 23020.

This is the first report of the interaction between the ORF6 SARS-CoV accessory protein and nsp8 and our findings suggest that ORF6 protein may play a role in virus replication.[ORF6] (Mus musculus) PubMed

 23021.

structure resembles that of the proposed tetrahedral intermediate during the deacylation step of normal peptidyl cleavage[ 3C-like peptidase] (Mus musculus) PubMed

 23022.

Here we report a complete description of the tetrapeptide substrate specificity of the essential major polyprotein processing protease 3Clpro using fully degenerate peptide libraries consisting of all 160,000 possible naturally occurring tetrapeptides. (Mus musculus) PubMed

 23023.

the 6 protein interacts with membrane-bound viral replication or assembly machinery to directly enhance virus replication and virulence in animals.(ORF6) (Mus musculus) PubMed

 23024.

Deletion of gene 7 had no effect on SARS-CoV replication in transformed cell lines, nor did it alter the induction of early apoptosis markers; viruses with gene 7 disruptions were not as efficient as wild-type virus in inducing DNA fragmentation (gene 7) (Mus musculus) PubMed

 23025.

Data suggest that regulation of IRF-3-dependent innate antiviral defenses by papain-like protease may contribute to the establishment of SARS-CoV infection. (Mus musculus) PubMed

 23026.

The nsp14 exonuclease activity requires Mg2+ as a cofactor [nsp14] (Mus musculus) PubMed

 23027.

The 29-nucleotide deletion disrupts the proper expression of the SARS-CoV ORF8 in human but not animal viruses. [ORF8 protein] (Mus musculus) PubMed

 23028.

Data first reported monomer structure for SARS-coronavirus 3C-like protease, the crystal structure of G11A mutant might provide insight into the dimerization mechanism of the protease [CoV 3CL(pro)] (Mus musculus) PubMed

 23029.

analysis of Nsp15 hexamer interaction with RNA [NSP15] (Mus musculus) PubMed

 23030.

data consistent with a cysteine protease (3CLpro) mechanism utilizing an "electrostatic" trigger to initiate acylation, cysteine-histidine catalytic dyad ion pair, an enzyme-facilitated release of P1 & general base-catalyzed deacylation reaction [3CLpro] (Mus musculus) PubMed

 23031.

PLnc domain of NSP3 acts as a replication/transcription scaffolding protein. [NSP3] (Mus musculus) PubMed

 23032.

N-finger of SARS-CoV main protease is not only critical for its dimerization but also essential for the enzyme to form the enzymatically active dimer[protease] (Mus musculus) PubMed

 23033.

SARS-CoV nsp1 suppressed host innate immune functions, including type I IFN expression, in infected cells [nsp1] (Mus musculus) PubMed

 23034.

model for viral entry is presented in which S2-HR2 is in a dynamic equilibrium between an ensemble of unstructured monomers in the transition state and a structured trimer in the prefusion state[ S2-HR2] (Mus musculus) PubMed

 23035.

Based on the X-ray structure of 3CL(Pro) co-crystallized with a trans-alpha,beta-unsaturated ethyl ester (Michael acceptor), a set of QM/QM and QM/MM calculations were performed, yielding three models with increasingly higher the number of atoms.[3CLPro] (Mus musculus) PubMed

 23036.

ORF-6 induces apoptosis via Caspase-3 mediated, ER stress and JNK-dependent pathways. (Mus musculus) PubMed

 23037.

Protein p6 enhances growth and replication of severe acute respiratory syndrome coronavirus. [p6] (Mus musculus) PubMed

 23038.

The hypothesis proposed that Glu47 of SARS CoVMpro is an important residue in the S3 subsite and is involved in binding with P3Lys of the octapeptide. (Mus musculus) PubMed

 23039.

N7-MTase of RNA life could function in lieu of that in DNA life provides interesting evolutionary insight and practical possibilities in antiviral drug screening[ nsp14 ] (Mus musculus) PubMed

 23040.

SARS-CoV papain-like protease blocks the IRF3 pathway, blocks NF-kappaB induction, and is an IFN antagonist. [papain-like protease] (Mus musculus) PubMed

 23041.

ORF3b contains a consensus nuclear export sequence that enables it to translocate to mitochondria. [Orf3b] (Mus musculus) PubMed

 23042.

two adjacent mutations on the dimer interface resulted in completely different crystal structures of the enzyme, demonstrating the distinct roles of these two residues in maintaining the active conformation of SARS-CoV 3CL(pro) [3C-like protease] (Mus musculus) PubMed

 23043.

Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex of PHB1 and PHB2 involved in mitochondrial biogenesis and intracellular signaling (Mus musculus) PubMed

 23044.

the globular domain of the nucleic acid-binding region (NAB) represents a new fold, with a parallel four-strand beta-sheet holding two alpha-helices of three and four turns that are oriented antiparallel to the beta-strands. (NSP3) (Mus musculus) PubMed

 23045.

The SARS-CoV nsp12 is primer dependent on both homo- and heteropolymeric templates, supporting the likeliness of a close enzymatic collaboration with the intriguing RNA primase activity that was recently proposed for coronavirus nsp8 (nsp12). (Mus musculus) PubMed

 23046.

N-glycans present on the SARS-CoV spike glycoprotein consist mainly of high-mannose, hybrid and bi-, tri- and tetra-antennary complex glycans, and core fucose. [spike glycoprotein] (Mus musculus) PubMed

 23047.

Overall, these results demonstrate the multifunctional nature of the coronavirus papain-like protease domain as a viral protease, deubiquitinating enzyme, and interferon antagonist. (Mus musculus) PubMed

 23048.

analysis of how mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease (Mus musculus) PubMed

 23049.

Insight into complex mechanisms regulating the activity and dimerization of SARS 3CL(pro)[3CL(pro) protein] (Mus musculus) PubMed

 23050.

We show that mRNA cap methylation requires a third viral protein, nsp10 (Mus musculus) PubMed

 23051.

N protein of SARS Coronavirus interacts with the host cell proteasome subunit p42. [N] (Mus musculus) PubMed

 23052.

maturation and activity regulation [3C-like proteinase] (Mus musculus) PubMed

 23053.

Gel-shift experiments showed that both SARS-unique domain-C and a two-domain construct containing the middle domain (M) and the C-terminal domain of nsp3 bind to single-stranded RNA.[nsp3] (Mus musculus) PubMed

 23054.

Here, we studied the priming of SARS-CoV S by elastase and show an important role for residue Thr(795) in the S2 domain. [spike] (Mus musculus) PubMed

 23055.

results show that spike protein of SARS displayed on recombinant baculovirus or prolonged exposure to hypoxia can trigger the conversion of peripheral B cells and B lymphoma cells into Mac-1 positive macrophage-like cells[spike protein ] (Mus musculus) PubMed

 23056.

Results demonstrate that nsP13 requires the presence of a long 5'-overhang to unwind longer DNA duplexes (nsP13). (Mus musculus) PubMed

 23057.

A structural model of a pentameric bundle is proposed with cysteines, serines and threonines facing the pore. (ORF8a protein) (Mus musculus) PubMed

 23058.

conformational equilibria and intramolecular rate processes in nsp7 in solution at pH 6.5[nsp7] (Mus musculus) PubMed

 23059.

The authors dissected protein 6 using site-directed mutagenesis and found no evidence for a classical nuclear localization signal.[protein 6] (Mus musculus) PubMed

 23060.

M protein of SARS-CoV holds dominant cellular immunogenicity[M protein, strain TJF] (Mus musculus) PubMed

 23061.

Data suggest that in addition to ORF-3a, ORF-3b, and ORF-7a, ORF-6 is a new player involved in SARS-CoV-induced apoptosis [ORF-6] (Mus musculus) PubMed

 23062.

N protein could not inhibit IFN-beta production induced by overexpression of downstream signaling molecules. [nucleocapsid protein] (Mus musculus) PubMed

 23063.

small isoform of nsp8, which might play a crucial role in viral RNA synthesis, was found. [nsp8] (Mus musculus) PubMed

 23064.

an auto-release model of M(pro) from the polyproteins is proposed, which will help understand the auto-processing mechanism and the difference between the autocleavage and trans-cleavage proteolytic activities of SARS-CoV M(pro).[Mpro] (Mus musculus) PubMed

 23065.

Overall results proved downregulation of ERK1 by ubiquitin proteasomes and suppression of interaction between ERK1 and STAT1 as type I IFN antagonist function of SARS-CoV PLpro.[PLpro] (Mus musculus) PubMed

 23066.

expression, purification and crystallization of nsp10 in complex with nsp16 are reported; crystals diffracted to a resolution of 1.9A resolution [nsp10, nsp16] (Mus musculus) PubMed

 23067.

E protein was mainly found in the endoplasmic reticulum-Golgi intermediate compartment of infected cells. (Mus musculus) PubMed

 23068.

The main protease (M(pro)) of SARS-CoV is essential for the viral life cycle, and is considered to be an attractive target of anti-SARS drug development. (Review) (Mus musculus) PubMed

 23069.

Nuclear shuttling of 9b and its interaction with Crm1 are essential for the proper degradation of 9b and blocking the nuclear export of this protein induces apoptosis.[9b protein] (Mus musculus) PubMed

 23070.

crystals of nsp2 belonged to space group P6(5), with unit-cell parameters a=b=112.8, c=91.1 A, alpha=beta=90, gamma=120 degrees [nsp2] (Mus musculus) PubMed

 23071.

The NMR study finds that the relaxation effects are consistent with an orientation corresponding to a trimer of parallel helices in both the presence and absence of trifluoroethanol. [heptad repeat 2] (Mus musculus) PubMed

 23072.

The structure of the nsp16/nsp10 interaction interface shows that nsp10 may stabilize the SAM-binding pocket and extend the substrate RNA-binding groove of nsp16, consistent with the findings in biochemical assays. [nsp10 & nsp16] (Mus musculus) PubMed

 23073.

The results define the SARS-CoV nsp(7+8) complex as an intriguing multimeric RNA polymerase that is capable of primer extension (nsp7, nsp8). (Mus musculus) PubMed

 23074.

the present study revealed that the nsp1 induced endonucleolytic RNA cleavage mainly near the 5' untranslated region of capped mRNA templates[nsp1] (Mus musculus) PubMed

 23075.

The domain of aa 65-107 of nsp10 was sufficient for its interaction with nsp16 and the region of aa 42-120 in nsp10, which is larger than the interaction domain, was needed for stimulating the nsp16 2'-O-methyltransferase activity.[nsp10, nsp16] (Mus musculus) PubMed

 23076.

The specific interaction of nsp1 with stem-loop 1 is an important strategy to facilitate efficient viral gene expression in infected cells, in which nsp1 suppresses host gene expression. [nsp1] (Mus musculus) PubMed

 23077.

This study investigates cytokine expression and proteomic change induced by SARS-CoV PLpro in human promonocyte cells. PLpro significantly increased TGF-beta1 mRNA expression (greater than fourfold) and protein production (greater than threefold). (Mus musculus) PubMed

 23078.

The ExoN domain is closely involved in the activity of the N7-MTase.[ N7-MTase] (Mus musculus) PubMed

 23079.

The amino acid residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling have been identified. [Nsp1] (Mus musculus) PubMed

 23080.

Critical residues of nsp14 essential for the methyltransferase activity on GTP were identified, which include F73, R84, W86, R310, D331, G333, P335, Y368, C414, and C416.[nsp14] (Mus musculus) PubMed

 23081.

Together, nsp3, nsp4, and nsp6 have the ability to induce double-membrane vesicles that are similar to those observed in SARS coronavirus-infected cells.[nsp3, nsp4, nsp6] (Mus musculus) PubMed

 23082.

Absence of nsp16 results in significant decreased viral replication. [nsp16] (Mus musculus) PubMed

 23083.

The expression of the membrane-anchored PLpro domain (PLpro-TM) from SARS-CoV inhibits STING/ TBK1/IKKepsilon-mediated activation of type I IFNs and disrupts the phosphorylation and dimerization of IRF3. (Mus musculus) PubMed

 23084.

the catalytic machinery of the SARS 3C-like protease by the S284-T285-I286/A mutations [3C-like protease] (Mus musculus) PubMed

 23085.

These experiments imply that the nsp10 surface that interacts with nsp14 and nsp16 and possibly other subunits of the viral replication complex may be a target for the development of antiviral compounds against pathogenic coronaviruses. (Mus musculus) PubMed

 23086.

VHL can inhibit SARS-CoV replication by regulating nsp16 ubiquitination and promoting its degradation. (nsp16 protein) (Mus musculus) PubMed

 23087.

analysis of the architecture of the nsp14-nsp10 complex involved in RNA viral proofreading [nsp14] (Mus musculus) PubMed

 23088.

SARS coronavirus ORF8 protein is acquired from SARS-related coronavirus from greater horseshoe bats through recombination. [ORF8] (Mus musculus) PubMed

 23089.

The overexpression of NPIPB3 restored the interferon-beta responses in severe acute respiratory syndrome coronavirus open reading frame 6 (SARS-CoV ORF6) expressing cells, indicating that the interaction of SARS CoV ORF6 and NPIPB3 reduced Type I interferon antagonism by SARS-CoV ORF6.[ORF6] (Mus musculus) PubMed

 23090.

Structural basis for the development of SARS 3CL protease inhibitors from a peptide mimic to an aza-decaline scaffold. (Mus musculus) PubMed

 23091.

In this study, we determined the crystal structure of 3CL(pro) with the C-terminal prosequence and the catalytic-site C145A mutation, in which the enzyme binds the C-terminal prosequence of another molecule. [3CL(pro)] (Mus musculus) PubMed

 23092.

The results showed that SARS coronavirus papain-like protease (PLPro) stimulated TGF-beta1-dependent expression of Type I collagen via activating STAT6 pathway.[PLPro] (Mus musculus) PubMed

 23093.

To understand the influence of a viral factor in relation to interspecies spillover, we studied the papain-like protease (PLP) of SARS-CoV. This key enzyme drives the early stages of infection as it cleaves the viral polyprotein, deubiquitinates viral and cellular proteins, and antagonizes the interferon (IFN) response. (papain-like protease, PLP) (Mus musculus) PubMed

 23094.

The authors identified F427I in the transmembrane domain of the GP2 subunit as reducing infectivity in a reconstituted viral system.[GP2] (Mus musculus) PubMed

 23095.

Authors describe a novel compound (compound 0013) that blocks the JUNV Z-Tsg101 interaction and inhibits budding of virus-like particles.[Z protein] (Mus musculus) PubMed

 23096.

Mutation F427I in the transmembrane region of Junin virus envelope glycoprotein GP2 has been shown to attenuate the neurovirulence of Junin virus in suckling mice.[GP2] (Mus musculus) PubMed

 23097.

The data show that mutation of each of the five RNase catalytic residues of pichinde viral nucleoprotein (NP) exoribonuclease diminishes the interferon suppression activity and slightly reduces the viral RNA replication activity.[NP] (Mus musculus) PubMed

 23098.

A model for a rod composed of two hexamers of Phycocyanin and two hexamers of Phycoerythrin was built using an in silico approach and the three-dimensional structures of both phycobiliproteins from Gracilaria chilensis.[Phycocyanin, Phycoerythrin] (Mus musculus) PubMed

 23099.

An understanding of the HypT-mediated mechanism would be helpful for controlling many pathogenic bacteria by counteracting bacterial HOCl defense mechanisms (Mus musculus) PubMed

 23100.

Surface-enhanced infrared absorption spectroscopy (SEIRAS) demonstrates that the high pKa is due to Glu325 (helix X), which must be protonated for LacY to bind galactoside effectively.[LacY] (Mus musculus) PubMed

 23101.

The locus Grain Number Increase 1 (GNI1) is shown here to be an important contributor to floret fertility.[GNI1] (Mus musculus) PubMed

 23102.

Mechanistic studies reveal that MeXis interacts with and guides promoter binding of the transcriptional coactivator DDX17. The identification of MeXis as a lncRNA modulator of LXR-dependent gene expression expands understanding of the mechanisms underlying cell type-selective actions of nuclear receptors in physiology and disease. (Mus musculus) PubMed

 23103.

Polymorphism analysis of the apxIA gene of Actinobacillus pleuropneumoniae serovar 5 isolated in swine herds from Brazil. (Mus musculus) PubMed

 23104.

The polycystic-kidney-disease domain of Vibrio anguillarum protease Epp specifically binds Ca2+, with enhanced conformational stability (Epp). (Mus musculus) PubMed

 23105.

platelet-derived GPIbalpha proved critical for development of non-alcoholic steatohepatitis and subsequent hepatocellular carcinoma.[GpIbalpha] (Mus musculus) PubMed

 23106.

HIV-1 gp41 promotes viral endocytosis in a CD4-independent manner by interacting with the host protein POB1.[gp41] (Mus musculus) PubMed

 23107.

Nitric oxide synthase role in water stress response.[nitric oxide synthase] (Mus musculus) PubMed

 23108.

MiR160 modulates gibberellin -mediated floral developmental and grapevine parthenocarpic regulation via its negative regulation of auxin-responsive factors activity.[Mir160] (Mus musculus) PubMed

 23109.

We found that the Geh lipase, but not other S. aureus lipases, prevents activation of innate cells in culture. Mutation of geh leads to enhancement of proinflammatory cytokine production during infection, increased innate immune activity, and improved clearance of the bacterium in infected tissue. (Mus musculus) PubMed

 23110.

study provides biochemical and biophysical data of a key cytochrome from G. metallireducens, paving the way to understand the extracellular electron transfer mechanisms in these bacteria. (Mus musculus) PubMed

 23111.

ZmVP1 interacts with ZmABI5 and regulates ZmGOLS2 expression and raffinose accumulation in maize seeds.[VP1, GOLS2, ABI5] (Mus musculus) PubMed

 23112.

The cap disruption mutant exhibited dramatic reduction in hyphal growth, conidiation, and spore germination, while an enhanced production of the sclerotia was observed in this mutant.[CAP] (Mus musculus) PubMed

 23113.

PELPIII N-terminal domain is a key determinant in PELPIII's function in regulating interspecific pollen tube growth [ PELPIII ] (Mus musculus) PubMed

 23114.

WRKY27 expression and role in the leaf senescence. [WRKY27] (Mus musculus) PubMed

 23115.

Results show that ccmC and ccmE traffick heme via their WWD domain and propose the structural basis for stereochemical attachment of heme. [ccmC & ccmE] (Mus musculus) PubMed

 23116.

ncc2b expression is dependent on prolactin's downstream activation of Stat5 and its subsequent nuclear translocation within branchial ionocytes.[Ncc2b, stst5] (Mus musculus) PubMed

 23117.

Results indicate that a structural element in the HA segment viral RNA may influence fitness. Examination of naturally evolved sequences in human hosts indicates a preference for the unfolded state of this structural element compared to that found in swine hosts. [HA] (Mus musculus) PubMed

 23118.

oxidative stress caused by hydrogen peroxide leads to upregulation of the ght5 gene in S. pombe.[Ght5] (Mus musculus) PubMed

 23119.

AGLF activates MtAG in transcriptional levels in control of floral organ identity.[AGLF, MtAG] (Mus musculus) PubMed

 23120.

This response was characterized by a change in anionic membrane phospholipid composition induced by point mutations in the phospholipid biosynthesis gene, cls2, encoding cardiolipin synthase. Single cls2 point mutations were sufficient for daptomycin resistance, antibiotic treatment failure, and persistent infection (Mus musculus) PubMed

 23121.

Rv1016c interferes in differentiation of the DCs by targeting suppressor of cytokine signaling (SOCS) 1 and SOCS3 expression, which subsequently leads to the reduction in STAT-1 and STAT-6 phosphorylation.[Rv1016c] (Mus musculus) PubMed

 23122.

Vipp1 is highly dynamic, exchanging between two fractions - a punctate fraction at the cell periphery, and a diffuse fraction that is uniformly distributed in the cytoplasm. [Vipp1] (Mus musculus) PubMed

 23123.

Study shows that RluE recognizes a relatively large part of 23S rRNA comprising H89 and its flanking regions which likely contributes to its high specificity of modifying a single, conserved uridine. Several structural elements were shown to be important for specific RNA recognition such as the loop L7-8 as well as electrostatic interactions from the basic residues in loop L1-2 and in the flexible N-ter region. [RluE] (Mus musculus) PubMed

 23124.

Structural basis and mechanism of the unfolding-induced activation of HdeA [HdeA] (Mus musculus) PubMed

 23125.

The data indicate that expression of alpha-toxin is a major factor causing S. aureus infections in cystic fibrosis mice.(alpha-toxin, Staphylococcus aureus) (Mus musculus) PubMed

 23126.

Mrx15 contacts mitochondrial translation products during their synthesis and plays, together with the ribosome receptor Mba1, an overlapping role in cotranslational protein insertion.[Mrx15, Mba1] (Mus musculus) PubMed

 23127.

pyruvate-bound crystal structures of ADP-glucose pyrophosphorylase from the bacterium Agrobacterium tumefaciens, identifying a previously elusive activator site for the enzyme [ADP-glucose pyrophosphorylase] (Mus musculus) PubMed

 23128.

In this study,the homologues of S. cerevisiae Vma12 and Vma6 in C. albicans, named Vph2 and Vma6, were identified. Vph2 and Vma6 play an essential role in correct localization of V-ATPase subunits Vph1 and Tfp1, and maintenance of endocytic trafficking and vacuolar pH. [VMA6] (Mus musculus) PubMed

 23129.

Results suggest that the electrically modified rim, the membrane-embedded wild-type MdfA exhibits a significant probability of an inward-closed conformation, which is further increased by drug binding. Since MdfA binds drugs from its inward-facing environment, these results raise the possibility that the transporter has a sensitive, drug-induced conformational switch, which favors an inward-closed state. [MdfA] (Mus musculus) PubMed

 23130.

The gene RcPAL is a key gene in castor lignin biosynthesis and can be induced to express under mechanical damage stress.[RcPAL] (Mus musculus) PubMed

 23131.

PbrSLAH3 crossing-talk with PbrCPK32 probably participate in transporting of nitrate nutrition in pear root.[PbrSLAh3, PbrCPK32] (Mus musculus) PubMed

 23132.

down-regulated lncRNA MBNL1-AS1 might promote the proliferation and inhibit the apoptosis of skeletal muscle cells by upregulating KCNMA1 expression. (Mus musculus) PubMed

 23133.

the biophysical interaction between SpAdK and Cps2D plays an important role in enhancing Cps2D phosphorylation, which results in increased capsular polysaccharide synthesis.[SpAdK, Cps2D] (Mus musculus) PubMed

 23134.

CircRNA_104670 is highly expressed in the nucleus pulposus (NP) tissues of intervertebral disc degeneration and acts as a ceRNA during NP degradation. [CircularRNA_104670] (Mus musculus) PubMed

 23135.

This work biochemically and structurally characterized two histidine and aspartic domain proteins YGK1 (YGL101W) and YB92 (YBR242W) from Saccharomyces cerevisiae as nucleoside 5'-monophosphatases, with substrate preference for deoxyribonucleoside 5'-monophosphatase over ribonucleoside 5'-monophosphatase. [YGK1] (Mus musculus) PubMed

 23136.

Brr6 interacts with chromatin, helping to maintain normal chromatin architecture and transcriptional regulation of certain loci at the nuclear envelope.[Brr6] (Mus musculus) PubMed

 23137.

the accumulation of TbPOLIC foci at active kDNA replication sites (antipodal sites) during stage II of the kDNA duplication cycle.[TbPOLIC] (Mus musculus) PubMed

 23138.

RIB72A and RIB72B are crucial for the structural assembly of ciliary A-tubule MIPs and are important for proper ciliary motility.[RIB72A, RIB72B] (Mus musculus) PubMed

 23139.

TORC2--both rapamycin and mGluR activation regulate mTOR complex 2 (mTORC2) activity, and mTORC2-deficient mice show impaired mGluR-LTD and associated behaviors (Mus musculus) PubMed

 23140.

Ferredoxin crystal structure with photosystem I complex reveals how ferredoxin binding entails loss of the exact three-fold symmetry of the photosystem I's soluble subunits.[Ferredoxin] (Mus musculus) PubMed

 23141.

HCV contains a positive sense single-stranded RNA genome and replicates with the aid of an RNA-dependent RNA polymerase known as nonstructural protein 5B (NS5B). In this study, molecular dynamic simulations were initiated from multiple crystal structures to understand the free energy landscape explored by the enzyme as it interconverts between different conformations. [nonstructural protein 5B] (Mus musculus) PubMed

 23142.

Viperin knockdown and overexpression in Enterovirus A71 (EVA71) infected cells indicated that this protein can markedly inhibit EVA71 infection [Viperin]. (Mus musculus) PubMed

 23143.

Structure of DapB from N. gonorrhoeae determined at 1.85A. This enzyme uses NAD(P)H as cofactor. Details of the interactions of the enzyme with its cofactors and a substrate analog/inhibitor are discussed. A large scale bioinformatics analysis of DapBs' sequences is also described. [DapB] (Mus musculus) PubMed

 23144.

This study compared the expression of p63 and calponin in canine mammary neoplasms.[calponin] (Mus musculus) PubMed

 23145.

These data demonstrate that RstA is a transcriptional repressor that autoregulates its own expression and directly inhibits transcription of the TcdA and the TcdB toxin genes and two positive toxin regulators, thereby acting at multiple regulatory points to control toxin production.[RstA] (Mus musculus) PubMed

 23146.

The show that deletion of the popZ gene causes abnormal cell elongation, minicell formation, DNA missegregation, and impairs motility. Overproduction of PopZ results in PopZ-rich regions near the poles, which are devoid of larger macromolecules, such as ribosomes, chromosomal DNA, and polyhydroxybutyrate (PHB) granules.[PopZ] (Mus musculus) PubMed

 23147.

Leu1 isopropylmalate isomerase mediated leucine biosynthesis crucially promotes vegetative growth, conidiogenesis, and pathogenicity of M. oryzae.[Leu1 isopropylmalate isomerase] (Mus musculus) PubMed

 23148.

overexpression of miR-125a-5p suppresses the expression of TNFRSF1B and promotes osteoclast differentiation.[TNFRSF1B] (Mus musculus) PubMed

 23149.

The transcription factors of NIA1 andNIA2 promoters and NRE2 cis-elements were screened.[NIA1, NIA2] (Mus musculus) PubMed

 23150.

The stability for AmtB bound to different lipids do not vary significantly between ion mobility mass spectrometry and mass spectrometry ion mobility mass spectrometry measurements, and no correlation to biophysical parameters, such as equilibrium dissociation constants, was found. [AmtB] (Mus musculus) PubMed

 23151.

directly mediates pigment degradation by chromophore detachment - [NblB] (Mus musculus) PubMed

 23152.

The authors propose a model whereby SecA directs SpA precursors to lipoteichoic acid-rich septal membranes for YSIRK/GXXS motif cleavage and secretion into the cross-wall. [SecA, staphylococcal protein A] (Mus musculus) PubMed

 23153.

This work uncovers a virulence strategy in which the Verticillium dahliae secretory protein VdSCP41 directly targets plant transcription factors to inhibit immunity, and reveals Arabidopsis CBP60g, SARD1 and cotton CBP60b as crucial components governing Verticillium dahliae resistance.[VdSCP41] (Mus musculus) PubMed

 23154.

these results uncovered a novel mechanism of persister formation mediated by SmpB under aminoglycosides treatments.[SmpB] (Mus musculus) PubMed

 23155.

we demonstrate here with ample evidence that severe SMA mice develop systemic inflammation, which is in part caused by microbial infection due to enhanced intestinal permeability. Persistent inflammation likely exacerbates SMA symptoms through multiple paths; one of which is through suppression of SMN expression via deteriorating SMN2 exon 7 splicing, highlighting a cell-nonautonomous mechanism that faci (Mus musculus) PubMed

 23156.

This study reveals that mitochondria rely on the homeostatic functions of autophagy to balance synthetic and degradative modes of POLG, which control copy number dynamics and stability of the mitochondrial genome.[POLG] (Mus musculus) PubMed

 23157.

CDK-mediated phosphorylation itself generated a phosphodegron of Mcm3, stimulating the degradation of Mcm3 resident in the nucleus.[Mcm3] (Mus musculus) PubMed

 23158.

Study shows that the co-translationalfolding state of a nascent domain can dramatically differ from its folding in the mature protein. The case of FtsY shows that such folding state, which is buried in the mature protein, is temporally exposed only during translation and executes a function, which is absent in the mature protein. FtsY shows an additional step of regulation present only in protein translation. [FtsY] (Mus musculus) PubMed

 23159.

CsUp encodes an Auxilin-like protein and controls pedicel orientation in cucumber.[CsUp] (Mus musculus) PubMed

 23160.

the high-affinity transporter BnPHT1;4 is involved in phosphorus acquisition and mobilization for facilitating seed germination and seedling growth of Brassica napus.[BnPHT1;4] (Mus musculus) PubMed

 23161.

Two casein kinase genes, Hd16 and Hd6, modulate the expression of florigen genes within certain restricted ranges of photoperiod, thereby fine-tuning the critical day length.[Hd6] (Mus musculus) PubMed

 23162.

EhRab21 is a unique member of small GTPase family in which an atypical switch-I Arginine is capable of driving GTP hydrolysis independent of the conserved switch-II Glutamine.[Rab21] (Mus musculus) PubMed

 23163.

functions of homoeologs in grain weight and protein content traits - [GW2] (Mus musculus) PubMed

 23164.

essential for nodule, nectary, leaf and flower development - [NBCL1] (Mus musculus) PubMed

 23165.

This study investigate global lncRNA expression profiles using microarray analysis of ulcerative colitis samples from Dextran Sulfate Sodium/Flagellin-challenged mice and identified a Flagellin-induced upregulated lncRNA (HIF1A-AS2). [flagellin] (Mus musculus) PubMed

 23166.

Overexpressing the CmTST2 gene in cucumber plants by stable transformation, both increased sucrose, fructose, and glucose accumulation in the fruit. The results indicate that CmTST2 plays an important role in sugar accumulation in melon fruit.[TST2] (Mus musculus) PubMed

 23167.

Transposition of Tn1213 encoding the PER-1 extended-spectrum beta-lactamase has been reported. [PER-1] (Mus musculus) PubMed

 23168.

Molecular characterization of IMP-1-producing Enterobacter cloacae complex isolates in Tokyo has been reported. [IMP-1] (Mus musculus) PubMed

 23169.

results indicated that PP2C34 is involved in alpha-amylase expression of gibberellin signal transduction pathway in rice (Mus musculus) PubMed

 23170.

The study indicates that LoiA regulates a variety of virulence-associated genes in S. Typhimurium. The negative regulation of Lon protease by LoiA indicates that LoiA can regulates several virulence-associated genes in S. Typhimurium via the Lon protease. (LoiA) (Mus musculus) PubMed

 23171.

Here, we demonstrate that Exported Protein (EXP1) is one of the dense granule proteins in merozoites, which is then transported to the parasitophorous vacuole membrane after invasion [EXP1]. (Mus musculus) PubMed

 23172.

increasing Cdr2 activity during cell growth promotes Wee1 localization to nodes, where inhibitory phosphorylation of Wee1 by Cdr1 and Cdr2 kinases promotes mitotic entry.[Wee1, Cdr2] (Mus musculus) PubMed

 23173.

Candida albicans N-acetylglucosaminylphosphatidylinositol de-N-acetylase (CaGpi12) is optimally active at 30 degrees C and pH 7.5. It is a metal-dependent enzyme that is stimulated by divalent cations. CaGPI12 is essential for growth and viability of C. albicans. Its loss causes reduction of GlcNAc-PI de-N-acetylase activity, cell wall defects and filamentation defects. (Mus musculus) PubMed

 23174.

From our study, we revealed the structure and function of S. aureus YabJ as a novel chlorination-activated ribonuclease. The present study will contribute to an in-depth understanding of chlorination as a post-translational modification. (Mus musculus) PubMed

 23175.

TRPM2 exhibits unique structural features that correlate with its function. The pore is larger and more negatively charged, consistent with its high Ca(2+) selectivity and larger conductance.[TRPM2] (Mus musculus) PubMed

 23176.

The results described in the present study support an expanded classification of the type II DAH7PSs as type IIA and type IIB based on sequence characteristics, structure and function of the resultant proteins, and on defined physiological roles within primary or secondary metabolism (Mus musculus) PubMed

 23177.

nonmuscle myosin 2A replacement with myosin 2C1 permits gastrulation but not placenta vascular development in mice.[Myh2c1] (Mus musculus) PubMed

 23178.

direct membrane binding and self-interaction are necessary for Mmr1 function in mitochondrial inheritance.[Mmr1] (Mus musculus) PubMed

 23179.

Mutagenesis at multiple sites in Spc29 and Spc42 suggests that much of the phosphorylation on these two proteins is not essential but enhances several steps of mitosis.[Spc29, Spc42] (Mus musculus) PubMed

 23180.

Ync13 has a novel function as an UNC-13/Munc13 protein in coordinating exocytosis, endocytosis, and cell-wall integrity during fission yeast cytokinesis.[Ync13] (Mus musculus) PubMed

 23181.

TgGRA15II-induced M1 cells may dampen the M2 dominant pathogenesis of hepatic fibrosis and granulomatosis.[TgFRA15II] (Mus musculus) PubMed

 23182.

The crystal structure of Escherichia coli ArgRS has been solved in complex with tRNA(Arg). The structure shows a tight binding of tRNA on the synthetase through the identity determinant A20 from the D-loop, a tRNA recognition snapshot never elucidated structurally. This interaction of A20 involves 5 amino acids from the synthetase. Additional contacts via U20a and U16 from the D-loop reinforce the interaction. [ArgRS] (Mus musculus) PubMed

 23183.

Ehd1, acting downstream of Ghd7, regulates not only heading date but also yield potential [Ehd1] (Mus musculus) PubMed

 23184.

Bph6, a superior resistance gene that evolved long ago in a region where planthoppers are found year round could be very valuable for controlling agricultural insect pests. [Bph6 protein; rice] (Mus musculus) PubMed

 23185.

Bra010198 is a strong candidate gene for ftms, a male sterile mutant gene [ftms] (Mus musculus) PubMed

 23186.

The rcsB and rmpA mutants are hypermucoviscous phenotype negative and have reduced capsule gene expression. In a murine pneumonia model, the regulator mutants have a range of colonization defects, suggesting that they regulate virulence factors in addition to capsule.[rcsB, rmpA] (Mus musculus) PubMed

 23187.

this work elucidates a novel mechanism by which Npr1 and Par32 exert regulatory feedback on TORC1.[Npr1, Par32] (Mus musculus) PubMed

 23188.

Cdk1 promoted APC/C-Cdh1-mediated Cdh1 degradation, whereas polo kinase Cdc5 elicited SCF-Cdc4-mediated degradation.[Cdh1, Cdc4] (Mus musculus) PubMed

 23189.

SNP alleles in NRAMP-2 and OPAQUE1 genes are associated with sensitivity to salt tolerance in wheat and upon validation can be exploited in the development of salt-tolerant wheat varieties. [NRAMP-2; OPAQUE1] (Mus musculus) PubMed

 23190.

Pid3-I1, one of the multiple alleles at the Pid3 locus, confers race-specific partial resistance to rice blast [Pid3] (Mus musculus) PubMed

 23191.

Results demonstrate that Bmdacapo was able to induce G1/S phase arrest in the cell cycle. In silkworm cells, Bmdacapo inhibits the expression of Pcna, CDK4 and CDK2, which affects the cell cycle and ultimately inhibits cell proliferation. [dacapo] (Mus musculus) PubMed

 23192.

The authors created a Toxoplasma strain that conditionally expresses TgPHYb and report that TgPHYb is required for optimal parasite growth under normal growth conditions.[TgPHYb] (Mus musculus) PubMed

 23193.

The authors demonstrate that MpkB is important for conidiation and that its deletion induces a copious increase of dihydroxynaphthalene (DHN)-melanin production.[MpkB] (Mus musculus) PubMed

 23194.

Chaperone-mediated secretion switching from early to middle substrates in the type III secretion system encoded by Salmonella pathogenicity island 2 [SPI2] (Mus musculus) PubMed

 23195.

17beta-estradiol accelerates the process of oocyte meiosis resumption via G protein-coupled receptor 30 (GPR30). GPR30 mediated gap junction permeability downregulation resulted from GPR30-MAP kinase-dependent phosphorylation of Cx43. [G protein-coupled receptor 30] (Mus musculus) PubMed

 23196.

an apoplastic peptide that activates salicylic acid signalling - [ZIP1] (Mus musculus) PubMed

 23197.

strict temporal regulation of M-phase cyclin-dependent kinase (CDK; M-CDK) is important for polarity establishment and morphogenesis. Cells with premature M-CDK activity caused by loss of checkpoint kinase Swe1 failed to polarize and underwent anaphase without budding. Mutants with increased Swe1-dependent M-CDK inhibition showed additional or more penetrant phenotypes in RTG than mitosis (Mus musculus) PubMed

 23198.

Using this rat model, we demonstrated that some of the major virulence factors of Bordetella are not involved in cough production, but an anti-sigma factor, BspR/BtrA, of B. bronchiseptica regulates the production of unknown cough-causing bacterial factor(s) [BspR/BtrA]. (Mus musculus) PubMed

 23199.

Fibronectin-binding protein B (FnBPB) from Staphylococcus aureus protects against the antimicrobial activity of histones [FnBPB] (Mus musculus) PubMed

 23200.

Data found that OspA folded through a productive on-pathway folding intermediate, in which the N-terminal domain of the protein was folded into the native structure with the C-terminal domain still unfolded. An overlapping region was shown between the N-terminal and the C-terminal folding units and that this overlapping region plays a critical role in determining the folding behavior of OspA. [OspA] (Mus musculus) PubMed

 23201.

This PilB formed a hexamer in solution and exhibited highly robust ATPase activity.[pilB] (Mus musculus) PubMed

 23202.

The first structure of a hydroxyquinol 1,2-dioxygenase from the Gram-negative bacterium Pseudomonas putida DLL-E4 (PnpC) at the resolution of 2.1A, is reported.[PnpC] (Mus musculus) PubMed

 23203.

novel lncRNA, Bmcob, which modulated osteogenic differentiation of primary mouse bone marrow mesenchymal stem cells.[Bmcob] (Mus musculus) PubMed

 23204.

regulator of plant height - [COLD1] (Mus musculus) PubMed

 23205.

encodes a P-type ATPase is involved in fruit organic acid accumulation - [M10] (Mus musculus) PubMed

 23206.

Copper(II) complexes with the studied ZnuD regions are thermodynamically more stable than the zinc(II) ones-Cu(II) complexes dominate in solution even in close to physiological ratios of the studied metal ions (a 10-fold excess of Zn(II) over Cu(II)). [ZnuD] (Mus musculus) PubMed

 23207.

These results demonstrate that at least two transcription factors , Sfl2 and Efg1, repress switching in a/alpha cells and that a/alpha strains with either an sfl2Delta or efg1Delta mutation can switch en masse but only under physiological conditions [Sfl2]. (Mus musculus) PubMed

 23208.

the importance of the dynamic nature of SecA-SecYEG interactions as a function of the preprotein substrate [SecA] (Mus musculus) PubMed

 23209.

of FT-B1 delayed the transition to reproductive growth, extended the duration of spike development, and increased spikelet number under different temperature regimes and photoperiod.[FT-B1] (Mus musculus) PubMed

 23210.

This study demonstrates that particular single nucleotide polymorphisms in rpoB lead to reduced fidaxomicin susceptibility. These mutations were associated with a fitness cost in vitro and reduced virulence in vivo. (Mus musculus) PubMed

 23211.

We uncovered that Rad51 associates with Hsp90, and upon DNA damage, this complex dissociates to facilitate the loading of Rad51 onto broken DNA [rad51]. (Mus musculus) PubMed

 23212.

Glycerol dehydration in the presence of the coenzyme-B12-dependent enzyme proceeds via a 1,2-OH shift, which benefits from a significant catalytic reduction in the barrier. In contrast, the same reaction in the presence of the coenzyme-B12-independent enzyme is unlikely to involve the 1,2-OH shift; instead, a strong preference for direct loss of water from a radical intermediate is indicated. [glycerol dehydratase] (Mus musculus) PubMed

 23213.

Glycerol dehydration in the presence of the coenzyme-B12-dependent enzyme proceeds via a 1,2-OH shift, which benefits from a significant catalytic reduction in the barrier. In contrast, the same reaction in the presence of the coenzyme-B12-independent enzyme is unlikely to involve the 1,2-OH shift; instead, a strong preference for direct loss of water from a radical intermediate is indicated. [glycerol dehydratase] (Mus musculus) PubMed

 23214.

HlyU virulence transcription factor and toxin-network of V. vulnificus and demonstrated that FTH, exhibits a potential to inhibit the pathogenesis of deadly, opportunistic human pathogen, V. vulnificus without inducing AMR. (Mus musculus) PubMed

 23215.

The P. vivax rhoptry neck protein 2 (PvRON2) is a highly conserved protein which is expressed in late schizont rhoptries; it interacts directly with AMA-1 and might be involved in moving-junction formation. (Mus musculus) PubMed

 23216.

The TORC1 signaling modulates DNA replication to coordinate cell growth and genome replication in response to nutrient availability. (TORC1 protein complex, S cerevisiae) (Mus musculus) PubMed

 23217.

a phosphorylation target for protein kinase MdCIPK22 in response to drought - [SUT2.2] (Mus musculus) PubMed

 23218.

product binding motif of Lactobacillus reuteri 121 inulosucrase [inulosucrase] (Mus musculus) PubMed

 23219.

VP1 of chicken anemia virus contained functional nuclear localization signal and nuclear export signal motifs that modulated nuclear import and export through a CRM1-dependent pathway. Further, VP1 may play a role in the transport of VP2 from nucleus to cytoplasm [VP1]. (Mus musculus) PubMed

 23220.

Collectively, these data suggested that superantigens TSST-1, staphylococcal enterotoxin B and staphylococcal enterotoxin C facilitate infections by disruption of mucosal barriers through their binding to CD40, with subsequent expression of chemokines.[ TSST-1, staphylococcal enterotoxin B, staphylococcal enterotoxin C] (Mus musculus) PubMed

 23221.

The authors propose that RhpRS uses phosphorylation- and nutrition-dependent mechanisms to switch between regulating virulence and metabolism, and this functionality is widely conserved among bacterial species.[RhpRS] (Mus musculus) PubMed

 23222.

The authors demonstrate that Chs3-AP-2 interaction is mediated by the AP-2 mu subunit (Apm4) YXXPhi binding domain. They also show that in the absence of Chs3 recycling via AP-2, cells have abnormal cell wall composition, defective polarized cell wall deposition, and morphological defects.[Chs3, Apm4] (Mus musculus) PubMed

 23223.

The periplasmic region of FliL forms a ring assembly in the crystal with an inner diameter of around 8 nm, which is comparable to the size of the stator unit.[FliL] (Mus musculus) PubMed

 23224.

Our data suggested that the IN(SIM)-SUMO interaction motifs constitutes a new regulatory mechanism of HIV integrase functions and might be important for HIV-1 replication [integrase]. (Mus musculus) PubMed

 23225.

Knock-down of OsSMT1 expression by RNA interference resulted in phenotypic changes in transgenic rice.[OsSMT1] (Mus musculus) PubMed

 23226.

confers resistance to multiple pathogens in barley [Lr67] (Mus musculus) PubMed

 23227.

There are two ISG15 homologues in the large yellow croaker, both of which are likely to be involved in host immune defense against viral and bacterial infection.[ISG15] (Mus musculus) PubMed

 23228.

The findings indicate that the putative glutamate 5-kinase is a bona fide G5K with no activity as an aspartokinase. [G5K] (Mus musculus) PubMed

 23229.

Negative HrcA and positive sigma32 regulators coordinate the transcription of duplicate groELs (groEL) (Mus musculus) PubMed

 23230.

results reveal that Mgm1 plays an important role in mitochondrial dynamics and function, cell cycle progression, hyphal development and virulence in C. albicans (Mgm1) (Mus musculus) PubMed

 23231.

An RNA recognition motif (RRM)-containing RNA-binding protein, Musashi, occurs in 25 putative splice variants.The most abundant Musashi variant, 12, with a molecular mass of 60 kD, interacts with two clock-relevant members of RNA metabolism, the subunit C3 of the RNA-binding protein CHLAMY1 and the 5'-3' exoribonuclease XRN1.Musashi role in the temperature acclimation.[Musashi] (Mus musculus) PubMed

 23232.

TagA is a cytosolic protein tightly associated with the membrane. Analyses of the type VI secretion system (T6SS)sheath dynamics demonstrate that TagA captures the distal end of the sheath to stop its polymerization and to maintain it under the extended conformation. (Mus musculus) PubMed

 23233.

Results demonstrate that the NADH-dependent nitrite reductase (Nir) confers a significant benefit during fermentative growth that reflects fermentative ammonification rather than detoxification. (Mus musculus) PubMed

 23234.

Virulence factor PrtA of Vibrio parahaemolyticus is upregulated by two global regulators, OpaR and RpoS. OpaR and RpoS promote PrtA expression at the transcriptional level and affect the amount of extracellular PrtA. (Mus musculus) PubMed

 23235.

PncA mutations associated with pyrazinamide resistance in the isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan.[PncA] (Mus musculus) PubMed

 23236.

SseL significantly enhanced the virulence of Salmonella Pullorum in chickens and suppressed activation of the cellular NF-kappaB pathway, thus inhibiting cellular inflammatory cytokine expression.[SseL] (Mus musculus) PubMed

 23237.

Loss of rfaH affected lipopolysaccharide synthesis in both Yersinia pseudotuberculosis IP32953 and Yersinia pestis KIM6+, resulting in a shorter core oligosaccharide.[RfaH] (Mus musculus) PubMed

 23238.

OsPLS2 played an essential role in leaf senescence and its disruption triggered light-dependent leaf senescence in rice.[OsPLS2] (Mus musculus) PubMed

 23239.

important role in arsenate uptake and tolerance via regulation of the amount and location of Pi transporters - [NLA1 (Mus musculus) PubMed

 23240.

Altogether, these data implicate Candida glabrata Fab1 in azole tolerance through actin network remodeling.[Fab1] (Mus musculus) PubMed

 23241.

The results identified seven gene clusters that were repressed by TctR, including type VI secretion system-2, and three gene clusters that were significantly activated.[TctR] (Mus musculus) PubMed

 23242.

Elucidate two structures of Cas12a in complex with a guide RNA and with either single-stranded or double-stranded DNA targets, revealing the mechanisms of Cas12-mediated cis and trans cleavage of DNA substrates. (Mus musculus) PubMed

 23243.

required for phospholipid homeostasis and is negatively involved in hyperosmotic stress tolerance - [cytidinediphosphate diacylglycerol synthase 5 (CDS5)] (Mus musculus) PubMed

 23244.

PcrX small non-coding RNA is derived from the 3' UTR of the puf operon mRNA by RNase E-mediated cleavage.[PcrX] (Mus musculus) PubMed

 23245.

atomic detail of how the assembly of the three components (TcA, TcB, and TcC) activates the toxin [TcA, TcB, and TcC] (Mus musculus) PubMed

 23246.

the membrane associated Mce4A is more structured and more stable.[Mce4A] (Mus musculus) PubMed

 23247.

identification of two genes (copB and copL) encoded within the Staphylococcus aureus arginine-catabolic mobile element (ACME) that we hypothesized function in Cu homeostasis [copB and copL] (Mus musculus) PubMed

 23248.

A novel gene encoding the specialized alanine decarboxylase (AlaDC) in tea (Camellia sinensis) plants has been cloned and characterized. [AlaDC] (Mus musculus) PubMed

 23249.

An insertional mutant of topB3 displayed an increase in avrPphB expression and an increase in PPHGI-1 excision as well as reduced population growth in resistant and susceptible cultivars of bean.[topB3, avrPphB] (Mus musculus) PubMed

 23250.

BcMAF2 could repress flowering by directly activating BcTEM1.[BcMAF2, BcTEM1] (Mus musculus) PubMed

 23251.

Swimming exercises delayed the progression of atherosclerosis and prevents insulin resistance, possibly by upregulating miR-492 and downregulating resistin in aortic endothelium. (Mus musculus) PubMed

 23252.

We found that H. pylori-infected patients with cagA-positive had a significantly higher expression of MMP- 9 mRNA levels in comparison to H. pylori-infected patients with cagA-negative.[cagA; cytotoxin associated gene A] (Mus musculus) PubMed

 23253.

The docking studies of all selected inhibitors in the active site of FtsZ protein showed crucial hydrogen bond interactions with Val 207, Asn 263, Leu 209, Gly 205 and Asn-299 residues. The binding free energies of these inhibitors were calculated by the molecular mechanics/generalized born surface area VSGB 2.0 method (Mus musculus) PubMed

 23254.

the role of CoALS4210 in the ability of C. orthopsilosis to colonize and persist on biotic surfaces (CoALS4210) (Mus musculus) PubMed

 23255.

M20 participation in the reduction of mitochondrial DNA levels in pollen cells (M20). (Mus musculus) PubMed

 23256.

SPRTN and the proteasome operate as independent replication-coupled DNA-protein crosslink proteases, mediating the degradation of DNA-protein crosslinks. (Mus musculus) PubMed

 23257.

Cryo-EM structures of type II-A anti-CRISPRs (AcrIIA2 and its homolog AcrIIA2b) bound to S. pyogenes Cas9, reveals a temperature-dependent convergent inhibition mechanism between AcrIIA2 and AcrIIA4. (Mus musculus) PubMed

 23258.

PfIMC1l may have a role in the locomotion of Plasmodium.[PfImc1l] (Mus musculus) PubMed

 23259.

the role of SntB in the plant pathogen A. flavus (Mus musculus) PubMed

 23260.

REVIEW: the multifunctional bacteriophage T7 single-stranded DNA binding protein, Gp2.5 [gp2.5] (Mus musculus) PubMed

 23261.

The role of XynA aromatic residues W187, Y124, W144, Y128 and W63 in substrate binding.[XynA] (Mus musculus) PubMed

 23262.

Data report the three-dimensional structure of McpU-ligand binding domain (LBD) in complex with putrescine which bound to a negatively charged pocket in the membrane distal module of McpU-LBD. Analytical ultracentrifugation revealed that McpU-LBD is monomeric in solution and that ligand binding does not alter this oligomeric state. [McpU] (Mus musculus) PubMed

 23263.

Although deletion of this protease did not affect Brucella virulence in macrophage, the mutant strain was significantly attenuated in mice infection model at 1 week post infection, and the expression level of several cytokine genes was significantly changed in vivo.[lon protease] (Mus musculus) PubMed

 23264.

[beta defensing-1] beta-glucan-induced SBD-1 expression is mediated through the TLR-2-MyD88-NF-kappaB/MAPK pathway (Mus musculus) PubMed

 23265.

Study determined the structure of capsid protein gp87 and show that it has the same fold as decoration proteins in many other phages, despite lacking significant sequence homology. gp87 is significantly more stable than mesophilic homologs. gp87 structure reveals that the core ''beta tulip'' domain is conserved in trimeric capsid components across numerous double-stranded DNA viruses, including Herpesviruses. [gp87] (Mus musculus) PubMed

 23266.

yeast permeability transition pore is regulated by Cpr3, endogenous matrix Ca(2+), and reactive oxygen species, and that it is involved in yeast death.[Cpr3] (Mus musculus) PubMed

 23267.

TrCel6A, nonreducing end-acting cellobiohydrolase (EC3.2.1.91) from Trichoderma reesei; TrCel7A, reducing end-acting cellobiohydrolase (EC3.2.1.176) from T. reesei[cel6a] (Mus musculus) PubMed

 23268.

nuclear organization of motor neurons is dependent on inside-out positioning, orchestrated by N-cadherin, catenin, and afadin activities, controlling cell body layering on the medio-lateral axis.[Gamma catenin] (Mus musculus) PubMed

 23269.

This study reports the identification of a new bacterial azoreductase (AzoR) from Klebsiella oxytoca GS-4-08. AzoR, as a flavin-free, oxygen-insensitive enzyme, has a molecular mass of 22 kDa and a high substrate specificity for methyl red (MR).[AzoR] (Mus musculus) PubMed

 23270.

We demonstrate that three major Epa proteins, Epa1, Epa6, and Epa7, primarily contribute to both hydrophilic and hydrophobic interactions, suggesting the Epa adhesins in mediating specific and nonspecific adherence and implicating Epa genes in biofilm formation on abiotic surfaces. [Epa1; Epa6; Epa7] (Mus musculus) PubMed

 23271.

findings point to a developmental role of DUX4 misexpression in the pathogenesis of Facioscapulohumeral dystrophy type 1 (DUX4) (Mus musculus) PubMed

 23272.

BED-domain-containing immune receptors that confer diverse resistance spectra to yellow rust [Yr7, Yr5 and YrSP] (Mus musculus) PubMed

 23273.

identification of the YnaI channel as the Na(+)/K(+) cation-selective MS channel and solved its structure at 3.8 A by cryo-EM single-particle method (Mus musculus) PubMed

 23274.

Study shows for the first time that TcdB induces senescence in enteric glial cells, key cells in regulation of gastrointestinal tract physiology and pathology. [TcdB] (Mus musculus) PubMed

 23275.

The function of Ymc2p and BOU is to transport glutamate across the mitochondrial inner membrane and thereby play a role in intermediary metabolism, C1 metabolism and mitochondrial protein synthesis.[Ymc2p] (Mus musculus) PubMed

 23276.

The improved structure allows the identification of three new components in the cavity of hexon-the cleaved N terminus of precursor protein VI (pVIn), the cleaved N terminus of precursor protein VII (pVIIn2), and mature protein VI. The binding of pVIIn2-and, by extension, that of genome-condensing pVII-to hexons is consistent with the previously proposed dsDNA genome-capsid coassembly for adenoviruses. [pVI, pVII] (Mus musculus) PubMed

 23277.

Study describes the cloning and characterization of the galactokinase GalK from Streptomyces coelicolor. The results reveal that the enzyme maintains high activity over a broad pH and temperature range with broad substrate specificity. [GalK/SCO3138] (Mus musculus) PubMed

 23278.

Delivery of 0.2 microg/insect of dsRNA specific to vATPase-A and vATPase-E into female bed bugs dramatically impaired the laying and viability of eggs over time. Injection of the vATPase-E dsRNA decreased survival of the bed bugs over 30 d. [V-type proton ATPase subunit A; V-type proton ATPase subunit E] (Mus musculus) PubMed

 23279.

In contrast to the N-terminal periplasmic polypeptide-transport-associated (POTRA) domains, the C-terminal transmembrane beta barrel of BamA is mechanically more stable. Exposed to mechanical stress, beta barrel unfolds beta hairpins until unfolding has been completed. Thereby, the stability of beta barrel and beta hairpins are modulated by the POTRA, the membrane composition and the extracellular lid closing the beta ... (Mus musculus) PubMed

 23280.

Data show that mutant ZIKVs either lacking the VNDT motif or with a single amino acid substitution (N154A) in the glycosylation site are highly attenuated in their ability to cause morbidity and mortality in the mouse model and are compromised for neuroinvasion. These results provide evidence for a critical role of N-linked glycosylation of the E protein in ZIKV virulence and neuroinvasion. [E protein] (Mus musculus) PubMed

 23281.

The identification of TesG in this study reveals a type I secretion apparatus of P. aeruginosa that functions during the host-pathogen interaction [TesG]. (Mus musculus) PubMed

 23282.

FabH1 and FabH2 protein conformation and substrate specificity.The key role of Cys356 in maintaining catalytic activity of FabH2.[FabH1][FabH2] (Mus musculus) PubMed

 23283.

variants of Y227, N293 and Y321 of vibrio cholera cbb3, were studied.[Cbb3] (Mus musculus) PubMed

 23284.

participates in zygospore maturation - [PKS1] (Mus musculus) PubMed

 23285.

Top6B, which harbors the ATPase activity of topo VI, recognizes and exploits the DNA crossings present in supercoiled DNA to stimulate subunit dimerization by ATP. Top6B self-association in turn induces extensive DNA bending, which is needed to support duplex cleavage by Top6A.[Top6A, Top6B] (Mus musculus) PubMed

 23286.

Together, these data suggest that polymorphism in the CagA C-terminus is responsible for differential alterations in some, but not all, host cell signaling pathways.[CagA] (Mus musculus) PubMed

 23287.

a calcium-dependent lipid binding annexin that is a positive regulator of ABA-dependent stress tolerance - [ANN3] (Mus musculus) PubMed

 23288.

an F-box protein that mediates enhanced resistance to Verticillium dahliae - [ACIF1] (Mus musculus) PubMed

 23289.

required for mycorrhiza formation and lipid accumulation of Rhizophagus irregularis - [FatM] (Mus musculus) PubMed

 23290.

A comparative analysis of the corresponding genome loci from Bacillus licheniformis and B. subtilis revealed the absence of an aprAs promoter in B. subtilis and indicates that AprAs is a B. licheniformis species specific phenomenon. The discovery of AprAs is of great biotechnological interest since subtilisin Carlsberg is one of the main products of industrial fermentation by B. licheniformis. (Mus musculus) PubMed

 23291.

Two genes of the biosynthetic pathway of aromatic amino acids, ARO4 and TYR1, were demonstrated to be responsible for the 2-phenylethanol overproduction phenotype [ARO4; TYR1]. (Mus musculus) PubMed

 23292.

VPE1 and VPE2 mediates inorganic phosphate transport to vacuoles.[VPE1,VPE2] (Mus musculus) PubMed

 23293.

cascade with SPX4 integrates nitrogen and phosphorus signalling networks - [NRT1.1B] (Mus musculus) PubMed

 23294.

The crystal structures of PfuRecJ and the complex of PfuRecJ and two CMPs were determined. A channel with several positively charged residues might bind substrate ssDNA and/or release single nucleotide products.The complex interaction domain regulates enzymatic activity. The DHH domain of PfuRecJ interacts with the C-terminal beta-sheet domain of the GINS51 subunit in the tetrameric GINS complex. (Mus musculus) PubMed

 23295.

REVIEW: TrmD: A Methyl Transferase for tRNA Methylation With m(1)G37 (Mus musculus) PubMed

 23296.

The current study shows that gamma34.5 utilizes nucleolar protein NOP53 to facilitate the dephosphorylation of eukaryotic initiation factor eIF2alpha for efficient viral translation.[gamma34.5] (Mus musculus) PubMed

 23297.

Analysis revealed a hexameric assembly of DotO dimers associated with the inner membrane complex, and a DotB hexamer associated with the base of this cytoplasmic complex. The assembly of a DotB-DotO energy complex creates a cytoplasmic channel that directs the translocation of substrates through the T4SS. [DotO} (Mus musculus) PubMed

 23298.

Results show that the quorum sensing peptide Qsp1 as an important signaling molecule for both forms of sexual reproduction. Qsp1 is involved in various differentiation and molecular processes, including meiosis, and bisexual mating, at least in part through the control of pheromone. Cqs2 is identified as an important component of the Qsp1 signaling cascade during both bisexual and unisexual reproduction. [Qsp1 & Cqs2] (Mus musculus) PubMed

 23299.

Pv50 localized on the surface of merozoites and a specific interaction between Pv50 and PvMSP1 was detected, suggesting that Pv50-PvMSP1 forms a heterodimeric complex in P. vivax. (Pv50) (Mus musculus) PubMed

 23300.

In parallel to the previously well-described PBP3-substitutions R517H and N526K, the new Y528H mutation confers reduced aminopenicillin susceptibility. [PBP3] (Mus musculus) PubMed

 23301.

Study shows that zebrafish sec14l3, one of the Sec14-like phosphatidylinositol transfer proteins family members, specifically participates in artery and vein formation via regulating angioblasts and subsequent venous progenitors' migration during vasculogenesis via the regulation of VEGFR2 activation. (Mus musculus) PubMed

 23302.

interacts with the S1 protein and plays a role in viral replication - [UBXN1] (Mus musculus) PubMed

 23303.

Data show that S. aureus infection causes impaired glucose tolerance via secretion of an insulin-binding protein extracellular domain of LtaS (eLtaS) which blocks insulin-mediated glucose uptake. [LtaS] (Mus musculus) PubMed

 23304.

Hepatitis E Virus (HEV) Papain-Like Cysteine Protease (PCP)down-regulates Melanoma Differentiation-Associated Gene 5 (MDA5)-mediated activation of interferon beta induction in a dose-dependent manner. MDA5 protein expression is completely abolished in the presence of HEV PCP. (Mus musculus) PubMed

 23305.

Baseline hepatitis C (HCV) nonstructural 5A protein (NS5A)resistance associated amino-acid substitutions (RAS) in Scotland is high. The high rate of baseline RAS supports resistance testing to guide current patient treatment. (Mus musculus) PubMed

 23306.

control of meristem determinacy is uncoupled from enzymatic activity - [TPP4] (Mus musculus) PubMed

 23307.

transcription factor coordinating internode elongation and photoperiodic signals - [PINE1] (Mus musculus) PubMed

 23308.

CUL4 expression and photoprotective role for E3 ubiquitin ligase CUL4-DDB1 that may mediate blue-light signals to LHCSR1 and LHCSR3 gene expression.[CUL4] (Mus musculus) PubMed

 23309.

Study provides evidence that MAPK1 interacts with the subunits of the HSP90 foldosome complex. The HSP70 and HSP90 subunits of this complex are the possible substrates for LdMAPK1, suggesting an important role for this kinase in parasite survival and life cycle control. [MAPK1] (Mus musculus) PubMed

 23310.

Data report near-atomic-resolution structure of a full length pilotin-secretin (AspS-GspD) complex revealing its detailed assembly mode. The AspS subunits attach to the secretin channel surface with a 15:15 stoichiometric ratio to GspD subunits, and insert their amino terminus into the outer membrane. The AspS subunits interact with all three secondary structures of the S domain of GspD. [AspS and GspD] (Mus musculus) PubMed

 23311.

Deletion of CMK2 elevates the level of calcium/calcineurin signalling and increases the expression level of PMR1 and PMC1, which is dependent on Crz1.[Cmk2, Pmr1, Pmc1] (Mus musculus) PubMed

 23312.

SPL6 acts as a transcriptional repressor of IRE1.[IRE1] (Mus musculus) PubMed

 23313.

The deletion of the MNN2 gene in C. glabrata induces biofilm matrix and cell wall variabilities that increase the resistance to the antifungal drug treatments.[MNN2] (Mus musculus) PubMed

 23314.

SiMYB3 is specifically expressed in the foxtail millet under the low potassium stress conditions. SiMYB3 is a valuable genetic resource for the improvement of the potassium deficiency tolerance in foxtail millet.[ SiMYB3 ] (Mus musculus) PubMed

 23315.

A gacS mutant devoid of the periplasmic detector domain is severely defective in biofilm formation. Functional assays indicate that this effect is accompanied by concomitant changes in the expression of the two RsmY/Z small RNAs that control activation of GacA-regulated genes.[GacS] (Mus musculus) PubMed

 23316.

inducible overexpression improves both yield and disease resistance - [IPA1] (Mus musculus) PubMed

 23317.

Collectively, these results suggest that Acinetobacter baumannii OmpA can induce autophagy in HeLa cells through MAPK/JNK signaling pathway.[OmpA] (Mus musculus) PubMed

 23318.

ArlR and MgrA can bind to the promoter of rbf and repress its expression. ArlR and MgrA can also directly bind to the promoter of ica operon and enhance the expression of icaA and polysaccharide intercellular adhesin production. The data also indicate that the ArlR-MgrA regulatory cascade can promote the expression of aur by directly binding to its promoter and inhibit protein-mediated biofilm formation.[ArlR, MgrA] (Mus musculus) PubMed

 23319.

The authors tentatively assign the coding sequence (CDS) LIC13259, previously annotated as unknown function, as a novel protein that may play an important role in the host's invasion and immune evasion processes, contributing to the establishment of the leptospiral infection.[LIC13259] (Mus musculus) PubMed

 23320.

Our results implicate a conserved nature of SURFIN export to the red blood cell, particularly an important role of multiple glutamic acid and lysine residues in the SURFIN N-terminal region [SURFIN]. (Mus musculus) PubMed

 23321.

SET-18 deletion extended lifespan and increased oxidative stress resistance, dependent on daf-16 activity in the insulin/IGF pathway.[SET-18] (Mus musculus) PubMed

 23322.

Cnp1/CENP-A Despite the lack of sequence conservation, Schizosaccharomyces centromere DNA possesses intrinsic conserved properties that promote assembly of CENP-A chromatin. (Mus musculus) PubMed

 23323.

Cnp1/CENP-A Despite the lack of sequence conservation, Schizosaccharomyces centromere DNA possesses intrinsic conserved properties that promote assembly of CENP-A chromatin. (Mus musculus) PubMed

 23324.

These findings suggest the knockdown of AccSp1 may influence melanization so that the antioxidant enzyme activities and the harmful metabolites decreased.[AccSp1] (Mus musculus) PubMed

 23325.

Taken together, these results suggest that different environmental and metabolic inputs orchestrate the CdgD and CdgH diguanylate cyclase responses of Vibrio cholerae via c-di-GMP production and motility.[CdgD, CdgH] (Mus musculus) PubMed

 23326.

These data provide a novel functional assembly form of phycobiliproteins and a molecular-level description of the close association of FNRL with phycocyanin in both CpcG and CpcL phycobilisomes.[FNRL] (Mus musculus) PubMed

 23327.

Genome-scale association study of abnormal scale pattern in Yellow River carp identified previously known causative gene (FGFR1a1) in European mirror carp. [FGFR1a1] (Mus musculus) PubMed

 23328.

regulates abscisic acid-promoted anthocyanin accumulation - [bZIP44] (Mus musculus) PubMed

 23329.

a transcription factor that regulates dynamic biosynthesis of salicylic acid in defense against Phytophthora infestans infection - [ZIP61] (Mus musculus) PubMed

 23330.

role in H3K9 deacetylation and fiber initiation - [HDA5] (Mus musculus) PubMed

 23331.

The expression of recGwed in M. smegmatis cells was up-regulated during stationary phase/UV damage and down-regulated during MMS/H2 O2 treatment. These observations indicate the possible involvement of RecGwed in transactions during recombination events, that proceed though branched DNA intermediates (Mus musculus) PubMed

 23332.

SEED CAROTENOID DEFICIENT (SCD) encodes an enzyme that functions in the biosynthesis of plastid isoprenoids in maize (Zea mays). [SCD] (Mus musculus) PubMed

 23333.

Molecular dynamic (MD) simulation of elastase revealed that, amino acid residues located at the surface area and disulphide bridge in Cys-30 to Cys-58 were responsible for enzyme stability in organic solvents. (Mus musculus) PubMed

 23334.

BtCBM5 is responsible for increasing binding efficiency of BtLPMO10A-FL, whereas; BtAA10 domain is accountable for oxidative cleavage of recalcitrant chitin. (Mus musculus) PubMed

 23335.

overexpression leads to leaf surface modifications, improved drought tolerance, and no yield penalty under controlled growth conditions - [SHN1] (Mus musculus) PubMed

 23336.

the mRNA coding for the Ninein protein is listed as one of Qki protein-dependent alternative splicing targets.[Qki5] (Mus musculus) PubMed

 23337.

the activation of LmHslV was accompanied by a large conformational remodeling, which represents a yet unidentified layer of control of HslV activation.[LmHSIV] (Mus musculus) PubMed

 23338.

Genotype III grass carp reovirus (GCRV; representative strain, GCRV-104) belongs to the subfamily Spinareovirinae and encodes an outer-fiber protein, VP55, responsible for mediating the infection of target tissues by the virus and assisting the virus into cells. Fibulin-4/EFEMP2 protein was previously identified as a putative binding partner for VP55 in a yeast two-hybrid screening. Here, we have further characteri (Mus musculus) PubMed

 23339.

a novel, horizontally gene transferred copper resistance locus (copX and copL), uniquely associated with the staphylococcal cassette chromosome mec elements of the highly virulent, epidemic, community acquired methicillin resistant Staphylococcus aureus USA300, confers copper hyper-resistance. [copX] [copL] (Mus musculus) PubMed

 23340.

involved in ABA signalling pathways and positively regulates drought tolerance by regulating the expression of genes associated with stress - [ZIP62] (Mus musculus) PubMed

 23341.

The Tyr insertional residue of SsuE makes specific contacts across the dimer interface that may assist in the altered mechanistic properties of this enzyme. The Y118F SsuE variant maintained the pi-pi stacking interactions at the tetramer interface and had kinetic parameters similar to those of wild-type SsuE. [SsuE] (Mus musculus) PubMed

 23342.

positive-charged patch and stabilized hydrophobic core are essential for avirulence function - [AvrPib] (Mus musculus) PubMed

 23343.

TraN is a novel repressor of an Enterococcus conjugative type IV secretion system. [TraN] (Mus musculus) PubMed

 23344.

pckA gene plays a role in modulating the virulence of Porphyromonas gingivalis W83 W83. pckA-deficient Porphyromonas gingivalis W83 shows reduction in hemagglutination activity and alteration in the distribution of gingipain activity. (Mus musculus) PubMed

 23345.

cryo-electron microscopy structure of the Rh5-CyRPA-Ripr complex at subnanometre resolution, which reveals the organization of this essential invasion complex and the mode of interactions between members of the complex, and shows that CyRPA is a critical mediator of complex assembly [Ripr, CyRPA] (Mus musculus) PubMed

 23346.

genetic target for simultaneously improving the breadmaking and health-related traits - [Gli-D2] (Mus musculus) PubMed

 23347.

The bacterial SMC complex partners ScpA and ScpB move slowly relative to the diffusion of the chromosome. [ScpB] (Mus musculus) PubMed

 23348.

Microcin B17 synthetase is an octomeric protein complex converting ribosomally synthesized peptide microcin B17 into a DNA gyrase inhibitor. (Mus musculus) PubMed

 23349.

Upon stimulation with Streptococcus agalactiae, the On-pik3r3b expression level in liver, spleen, kidney and gill were significantly increased at 12h after infection. These observations strongly indicates that On-pik3r3b is involved in the innate immune response in Nile tilapia.[pik3r3b] (Mus musculus) PubMed

 23350.

activin is a novel candidate as a clinical marker to identify those acute pancreatitis patients with severe disease who would benefit from aggressive treatment and activin may be a therapeutic target in severe acute pancreatitis.[Activin] (Mus musculus) PubMed

 23351.

A combination of phosphoproteomic and transcriptomic analyses revealed both direct and indirect targets of PKA and provided a global perspective on its function. One of these targets was the transcription factor CreA, the main repressor responsible for carbon catabolite repression (CCR).[PKA, CreA] (Mus musculus) PubMed

 23352.

Tery_3377 has specificity for iron in the Fe3+ state, and an X-ray crystallography-determined structure uncovered a functional iron substrate-binding domain.[Tery_3377] (Mus musculus) PubMed

 23353.

LAP1 null mutant oocysts display highly reduced expression of sporozoite proteins and their transcription factors.[LAP1] (Mus musculus) PubMed

 23354.

The activated beta-integrin (CgbetaV) enhanced RGD-binding and phagocytic capabilities of hemocytes (CgbetaV). (Mus musculus) PubMed

 23355.

Deletion of the histone-like protein HU, CHU_2750, was not lethal to C. hutchinsonii, the mutant displayed an abnormal filamentous morphology, loose nucleoid, and obvious defects in the degradation of crystalline cellulose and cell motility. [CHU_2750] (Mus musculus) PubMed

 23356.

PhaR negatively regulates the expression of daptomycin biosynthetic gene cluster by direct binding to its promoter [PhaR] (Mus musculus) PubMed

 23357.

responsible for fruit acidity - [SAUR37 and PPWCH and ALMTII] (Mus musculus) PubMed

 23358.

These findings delineate a previously uncharacterized mechanism in which Rsp1-Mto1 interaction orchestrates non-spindle pole bodies microtubule formation.[Rsp1, Mto1] (Mus musculus) PubMed

 23359.

RRSP is a critical virulence factor that robustly inactivates Ras and Rap1 and augments the pathogenicity of invading bacteria via the combined effects of its N and C lobes.[RRSP] (Mus musculus) PubMed

 23360.

It has been suggested that 4EIP and EIF4E1 fine-tune mRNA levels in growing cells, and that 4EIP contributes to translation suppression during differentiation to the stumpy form. [4EIP], [EIF4E1] (Mus musculus) PubMed

 23361.

yeast glycolytic enzyme triose phosphate isomerase is aggregation-prone in response to cadmium and to glucose depletion in chronologically aging cultures.[Tpi1] (Mus musculus) PubMed

 23362.

High-speed photothermal off-resonance atomic force microscopy reveals the kinetics of centriolar scaffold protein SAS-6 ring formation and demonstrates that distinct biogenesis routes can be followed to assemble a nine-fold symmetrical structure. [SAS-6] (Mus musculus) PubMed

 23363.

The Escherichia coli maltose transporter MalFGK2 belongs to the protein superfamily of (ABC) transporters. This protein is composed of heterodimeric transmembrane domains MalF and MalG, and the homodimeric nucleotide-binding domains MalK2 . This study performed all-atom molecular dynamics simulations on the maltose transporter. [MalFGK2] (Mus musculus) PubMed

 23364.

TRU-1 is a chromosomally encoded Class C beta-Lactamase of Aeromonas enteropelogenes. TRU-1 crystals provided ultrahigh-resolution diffraction data for the native enzyme and for its complex with avibactam. [Tru-1] (Mus musculus) PubMed

 23365.

Results demonstrate that Xanthomonas citri-tolerance in transgenic citrus is significantly increased by the overexpression of CsAP2-09. This study may explain the role of CsAP2-09 in resistance to bacterial canker disease stress in citrus. (Mus musculus) PubMed

 23366.

HBZ suppresses TDP1 expression by inhibiting NRF-1 function in Adult T-cell leukemia cells.[HBZ] (Mus musculus) PubMed

 23367.

SmCalp1 and/or SmCalp2 perform fibronectin cleavage function to impede blood clot formation around the worms in vivo.[SmCalp1, SmCalp2] (Mus musculus) PubMed

 23368.

LvnPKC is involved in immune defense of L. vannamei exposed to hypothermal stress or infected witalginolyticush Vibrio (nPKC). (Mus musculus) PubMed

 23369.

Cation binding under equilibrium conditions has been used as a tool to explore the accessibility of permeant and nonpermeant cations to the selectivity filter in three different inactivated models of the potassium channel KcsA. The results show that the stack of ion binding sites (S1 to S4) in the inactivated filter models remain accessible to cations as they are in the resting channel state. [KcsA] (Mus musculus) PubMed

 23370.

This study uses the bacterial porin OmpF from E. coli as a model system to gain insight on the control of outer membrane permeability by bacterial porins through the modulation of their open state. This is an extensive study of the role of membrane lipids in the OmpF channel closure by voltage. [OmpF] (Mus musculus) PubMed

 23371.

PhoP furthers its activation by promoting Lon-mediated degradation of EIIA(Ntr) at acidic pH. These results suggest that Salmonella ensures robust activation of its virulence system by suspending the activation of PhoP until a sufficient level of active PhoP is present to overcome the inhibitory effect of EIIA(Ntr).[EIIA(Ntr)] (Mus musculus) PubMed

 23372.

HID2 binds Hb with higher affinity than HID1 and that the Hb tetramer is engaged by two Shr receptors.[Shr] (Mus musculus) PubMed

 23373.

The amplified genes of TRAP2 are 2817 bp in length, encoding a functional domain of about 938 aa with two vWFA domains, one TSP domain and one transmembrane domain. [TRAP2] (Mus musculus) PubMed

 23374.

This study reports the results from a kinetic-based study of L. lactis alpha-Phosphoglucomutase (alphaPGM),catalysis, which demonstrate enzyme activation by autocatalyzed phosphorylation of Asp8 with alpha-d-glucose 1-phosphate. [alpha-Phosphoglucomutase] (Mus musculus) PubMed

 23375.

IglE helps to prevent dynein- and MTOC-mediated intracellular trafficking in host cells to inhibit the transport of F. novicida toward lysosomes. [IglE] (Mus musculus) PubMed

 23376.

this study shows that Xenopus laevis macrophage-like cells produce XCL-1, an intelectin family serum lectin that recognizes bacteria [XCL-1) (Mus musculus) PubMed

 23377.

FeoAB, BtuS1 and BtuS2 are required for assimilation of iron released from heme. [FeoAB,BtuS1,BtuS2] (Mus musculus) PubMed

 23378.

A novel function of termite NLaz1 has contributed to social evolution from the cockroach ancestors of termites. These results indicated that a high larval NLaz1 expression is crucial for soldier determination through social communication in termites.[NLaz1] (Mus musculus) PubMed

 23379.

This complex includes S. pombe Ell1, Eaf1, and a previously uncharacterized protein we designate Ell1 binding protein 1 (Ebp1), which is distantly related to metazoan AFF family members. Like the metazoan SEC, this S. pombe ELL complex appears to function broadly in Pol II transcription. (Mus musculus) PubMed

 23380.

we conclude that CS30 is common among "CF negative" LT + STp isolates and is associated with enterotoxigenic Escherichia coli that cause diarrhea (Mus musculus) PubMed

 23381.

encodes a starch debranching enzyme isoamylase1, mutation results in endosperm sugar accumulation and pre-harvest sprouting - [PHS8] (Mus musculus) PubMed

 23382.

The authors suggest that force-enhanced adhesion may involve conformational changes in vWF. Under force, elongation of vWF may lead to the exposure of a high-affinity cryptic staphylococcal protein A (spa)-binding site to which bacteria firmly attach.[spa] (Mus musculus) PubMed

 23383.

The authors report here the identification of a novel Toxoplasma effector protein that is exported from the parasitophorous vacuole in a MYR1-dependent manner and localizes to the host's nucleus. Parasites lacking this inducer of host cyclin E (HCE1) are unable to modulate E2F transcription factor target genes, including cyclin E, and exhibit a substantial growth defect.[HCE1] (Mus musculus) PubMed

 23384.

This study used extensive molecular dynamics simulations combined with Markov state model analysis to investigate the interaction of l-Trp with the extracellular vestibule (EV) of MhsT and identified potential binding poses of l-Trp as well as induced conformational changes in the EV. [MhsT] (Mus musculus) PubMed

 23385.

The 91st arginine residue of Edwardsiella tarda flagellin is involved in inflammatory response through TLR5S, decreasing expression of interleukin-1beta and NF-kappaB genes in Japanese flounder, Paralichthys olivaceus.[FliC] (Mus musculus) PubMed

 23386.

The 91st arginine residue of Edwardsiella tarda flagellin is involved in inflammatory response through TLR5S, decreasing expression of interleukin-1beta and NF-kappaB genes in Japanese flounder, Paralichthys olivaceus. (Mus musculus) PubMed

 23387.

Bets-valienamine could increase the hydrogen bond probability and decrease the binding free energy between coenzyme pyridoxal phosphate and BtrR by regulating the protein structure of BtrR, which was conducive to the catalytic reaction. beta-valienamine maintained the formation of cation-p interactions between basic and aromatic amino acids in BtrR, thus enhancing its stability and catalytic activity. [BtrR] (Mus musculus) PubMed

 23388.

S-layer protein of SLCT-11 strains displays a complex glycan and suggest that this glycan is required for C. difficile sporulation and control of cell shape.[SLP} (Mus musculus) PubMed

 23389.

The Pro550 and Pro551-substituted mgtA gene promotes Salmonella's intramacrophage survival and mouse virulence, suggesting that EF-P-mediated translational control of the mgtA gene is required for Salmonella pathogenesis.[EF-P] (Mus musculus) PubMed

 23390.

Such inducible nature of Ylehd suggests its physiological role in xenobiotic stress mitigation. This study represents the first functional characterisation of a bifunctional EH/HLD in eukaryotic microbes with broad substrate specificity making it a potential biocatalyst for bioremediation/biosensing of mixed pollutants. (Mus musculus) PubMed

 23391.

The trimeric Hef-associated nuclease HAN is a 3'-->5' exonuclease and is probably involved in DNA repair. [HAN] (Mus musculus) PubMed

 23392.

Exopolysaccharide signaling cascades are independent of LuxO contribution and essentially involve sodium-driven flagellar motor and VpsR. [LuxO] (Mus musculus) PubMed

 23393.

The IL-17/AK081284/TGFbeta1 signaling pathway mediates high glucose induced collagen production.[lncRNA AK081284] (Mus musculus) PubMed

 23394.

The crystallographic and biophysical studies of Escherichia coli MCR-2 protein, encoded by colistin resistance gene mcr-2, reveal the substrate binding sites to Zinc and phosphoethanolamine. Through site-directed mutagenesis and functional studies, Thr293 is determined to be crucial for its enzyme activity. (Mus musculus) PubMed

 23395.

This study shows that RecA nucleoprotein filaments move along DNA substrates via short-distance facilitated diffusions, or slides, interspersed with longer-distance random moves, or hops. Importantly, from the specific interaction geometry, the double-stranded substrate DNA resides in the secondary DNA binding-site within the RecA nucleoprotein filament helical groove during the homology search. [RecA] (Mus musculus) PubMed

 23396.

miR156 switches on vegetative phase change under the regulation of redox signals in apple seedlings [miR156] (Mus musculus) PubMed

 23397.

These findings provide the first evidence that VP2 directly interacts with Apoptin in the nucleus to down-regulate apoptosis through alterations in the phosphorylation status of the latter. This information will be useful to further elucidate the underlying mechanism of viral replication in the CAV life cycle. (Mus musculus) PubMed

 23398.

the identification of Fkh1/2 binding sequence variants at replication origins and the recombination enhancer compared with Fkh1/2 binding sequences found at target genes of the CLB2 group.[Fkh1, Fkh2] (Mus musculus) PubMed

 23399.

This study identified the NRAP-1, an auxiliary protein in C. elegans that modulates NMDAR function. NMDAR-mediated currents were eliminated in nrap-1 mutants, as was NMDA-dependent behavior. (Mus musculus) PubMed

 23400.

High-resolution crystal structures of the eIF4E-eIF4G complex from Chaetomium thermophilum were determined. eIF4E. eIF4G. (Mus musculus) PubMed

 23401.

In Mycobacterium bovis-BCG, deletion of fmt could only be created after incubation of 6 weeks, with a generation time ~2 times longer than for wild-type bacteria. The results confirm the importance of this gene in pathogenic mycobacteria, but the deletion mutant is viable.[fmt] (Mus musculus) PubMed

 23402.

Insects injected with Diap1 dsRNA have approx. 1.5-2-fold higher levels of caspase activity than controls 24 hours post injection, providing biochemical evidence that inhibition of apoptotic activity by the Diap1 gene product has been decreased.[Diap1] (Mus musculus) PubMed

 23403.

CesT via its C-terminal tyrosine phosphosites, has relevant roles beyond typical type III secretion chaperones that interact and stabilize effector proteins. [CesT] (Mus musculus) PubMed

 23404.

CT699, CT775 and CT776 provide membrane lipid diversity in chlamydia trachomatis.[CT699, CT775, CT776] (Mus musculus) PubMed

 23405.

Cricket paralysis virus protein CrPV-1A comprises a BC-box motif to recruit an E3 ubiquitin ligase for Ago-2 degradation. [CrPV-1A] (Mus musculus) PubMed

 23406.

The peptidoglycan hydrolase cwlM gene plays a key regulatory role in biofilm formation in Mycobacterium tuberculosis and Mycobacterium smegmatis. This study provided a theoretical basis for using peptidoglycan hydrolase as a target for the inhibition of biofilms. [cwlM] (Mus musculus) PubMed

 23407.

Early endosome motility is crucial for alpha-amylase production and cell differentiation in A. oryzae.[alpha amylase] (Mus musculus) PubMed

 23408.

The mycobacterial enzyme cyclopropane synthase (PcaA)promotes angiogenesis via cis-cyclopropanation of Trehalose Dimycolate. pcaA mutation or Vegfa pathway blockade reduces bacterial growth in vivo [PcaA] (Mus musculus) PubMed

 23409.

The crystal structure and substrate specificity of Beta-ketoacyl-acyl carrier protein synthase III from Acinetobacter baumannii have been determined. (Mus musculus) PubMed

 23410.

TM XI forms part of the ion translocation core of this Na(+)/H(+) exchanger.[NHE1] (Mus musculus) PubMed

 23411.

early upon infection VacA induces transient increase of mitochondrial translocases and a dramatic accumulation of the mitochondrial DNA replication and maintenance factors POLG and TFAM.[Vaca] (Mus musculus) PubMed

 23412.

FAU-1, which is known to be an RNA binding protein, possesses an RNase activity against precursor 5S rRNA derived from P. furiosus and T. kodakarensis.[FAU-1] (Mus musculus) PubMed

 23413.

FAU-1, which is known to be an RNA binding protein, possesses an RNase activity against precursor 5S rRNA derived from P. furiosus and T. kodakarensis.[FAU-1] (Mus musculus) PubMed

 23414.

Results show that HCVncd is a typical intrinsically disordered protein. When it forms small ribonucleoprotein complexes with various RNA hairpins of the HCV genome, it compacts but remains intrinsically disordered. Above a critical RNA concentration, these ribonucleoprotein complexes rapidly and cooperatively assemble into large nucleocapsid-like particles, wherein the HCVncd subunits become substantially more extended. (Mus musculus) PubMed

 23415.

The results in this work reveal the arrangement of the fla2 divergent promoters showing that CtrA promotes transcriptional activation using more than a single architecture [CtrA]. (Mus musculus) PubMed

 23416.

Docking the model of the FlgK junction onto the structure of the Campylobacter hook provides some clues about its divergence.[FlgK] (Mus musculus) PubMed

 23417.

Collectively, the data presented in this work provide a robust molecular basis for the crucial role of MntABC in staphylococcal virulence.[MntABC] (Mus musculus) PubMed

 23418.

these results suggest that OsMTP11 predominantly functions as a Mn-transporting CDF with lower affinity for Zn. Site-directed mutagenesis studies revealed four substitutions in OsMTP11 that appear to alter its transport activity. (Mus musculus) PubMed

 23419.

XrpA is the first described negative regulator of ComRS systems in streptococci. [XrpA] (Mus musculus) PubMed

 23420.

Further analysis revealed that Edwardsiella piscicida phosphothreonine lyase promotes the dephosphorylation and ubiquitination of p65 by inhibiting the phosphorylation of mitogen- and stress-activated protein kinase-1 (MSK1) and by inhibiting the phosphorylation of extracellular signal-related kinase 1/2 (ERK1/2), p38alpha, and c-Jun N-terminal kinase (JNK).[phosphothreonine lyase] (Mus musculus) PubMed

 23421.

Hedgerow and Rosebush are Mycobacterium smegmatis Wag31-dependent phages and that Fruitloop gp52 confers heterotypic superinfection exclusion by inactivating Mycobacterium smegmatis Wag31. [Wag31] (Mus musculus) PubMed

 23422.

Physicochemical data indicated that SaSK is an unstable, hydrophilic, and acidic protein. Finally, structural information showed that SaSK presented folding that is typical of its homologous counterparts and contains the typical domains of this family of proteins. Amino acids that have been shown to be important for SaSK protein function are conserved. [SaSK] (Mus musculus) PubMed

 23423.

PTOX activity is critical for growth under intermittent light.[PTOX] (Mus musculus) PubMed

 23424.

The present study has shown that the pilus-1 tip protein RrgA of Streptococcus pneumoniae TIGR4 as well as its two terminal domains D3 and D4 bind to Fibronectin. [RrgA] (Mus musculus) PubMed

 23425.

The Ups1-independent and low-level phosphatidylethanolamine-enhanced cardiolipin accumulation was shown to depend on the functions of FMP30, MDM31, and MDM32.[Ups1, Fmp30, Mdm31, Mdm32] (Mus musculus) PubMed

 23426.

SpSlc4a10 is specifically expressed by calcifying primary mesenchyme cells with peak expression during de novo formation of the skeleton. Knock-down of SpSlc4a10 led to pH regulatory defects accompanied by decreased calcification rates and skeleton deformations. [Slc4a10] (Mus musculus) PubMed

 23427.

The authors conclude that Streptococcus pneumoniae PspA and PspC help the pneumococcus to evade complement attack by binding C4BP and so inactivating C4b.[PspA, PspC] (Mus musculus) PubMed

 23428.

The authors demonstrate that the Mip and PpiB are important for surfactant-dependent sliding motility and adaptation to suboptimal temperatures, features that contribute to the environmental fitness of Legionella pneumophila. Furthermore, they contribute to infection of the natural host Acanthamoeba castellanii as well as human macrophages and human explanted lung tissue.[Mip, PpiB] (Mus musculus) PubMed

 23429.

Staphylococcus aureus protein SpoVG can regulate the transcription of the Staphylococcus aureus proteins Rot, Spa and ClfB through direct-binding to their promoters. SpoVG can positively modulate the human fibrinogen-binding ability of S. aureus. [Rot] (Mus musculus) PubMed

 23430.

pig AMCase can function as a protease resistant chitin digestive enzyme at broad pH range present in stomach as well as in the intestine.[AMCase] (Mus musculus) PubMed

 23431.

Here, using the aquatic bacterium Shewanella oneidensis as a model organism, we demonstrate interplay between two proteins with antagonist activities, the Hsp90 chaperone and the HslVU protease, to finely regulate the level of an essential client of Hsp90 [Hsp90]. (Mus musculus) PubMed

 23432.

Scc3 is required for localization and chromatin association of Smc1 and Rec8.[Scc3] Scc2 is required for chromosome segregation in mitosis and double-stranded breaks repair in meiosis.Scc2 is not required for cohesin localization, but cohesin is required for the localization of Scc2.[Scc2] (Mus musculus) PubMed

 23433.

The data suggest that EmaA is a multifunctional adhesin that utilizes different mechanisms to enhance bacterial binding to collagen and to enhance biofilm formation, both of which are important for Aggregatibacter actinomycetemcomitans colonization and subsequent infection. (Mus musculus) PubMed

 23434.

In this study, by use of in vivo imaging, the authors identified hydrogen peroxide (H2O2) as a stressor produced in the lung during Acinetobacter baumannii infection and defined OxyR as a transcriptional regulator of the H2O2 stress response.[OxyR] (Mus musculus) PubMed

 23435.

Cytolytic toxin production by Staphylococcus aureus is dependent upon the activity of the protoheme IX farnesyltransferase [CyoE] (Mus musculus) PubMed

 23436.

Results identified a novel porcine PLA2G16-AS, which has a weak sequence conservation and complemented with its host gene, PLA2G16. PLA2G16-AS regulated the expression of PLA2G16 at the RNA level. A differential expression of PLA2G16-AS and PLA2G16 was observed in the adipose tissues of Tibetan pigs and Rongchang pigs, indicating that different breeds of pig might have different abilities to deposit fat. [PLA2G16-AS] (Mus musculus) PubMed

 23437.

The findings demonstrate a critical link between OsGRXS17, the modulation of guard cell hydrogen peroxide concentrations, and stomatal closure, expanding our understanding of the mechanisms governing plant responses to drought.[OsGRXS17] (Mus musculus) PubMed

 23438.

TH1 determines grain shape and size by regulating cell expansion in the lemma and palea of rice spikelet. TH1 functions as a transcriptional repressor in spikelet development. TH1 could form a homodimer.[TRIANGULAR HULL1 (TH1)] (Mus musculus) PubMed

 23439.

PvspL activation in the presence of VpsR, c-di-GMP and sigma70-RNAP. c-di-GMP does not significantly change the affinity of VpsR for PvpsL DNA or the DNase I footprint of VpsR on the DNA, and it is not required for VpsR to dimerize. c-di-GMP is required for VpsR to generate the specific protein-DNA architecture needed for activated transcription.VpsR. (Mus musculus) PubMed

 23440.

The structure of a Lig-E type DNA ligase bound to the nicked DNA-adenylate reaction intermediate confirms that complete encirclement is unnecessary for substrate engagement. Biochemical and biophysical measurements of point mutants to residues implicated in binding highlight the importance of basic residues in the OB domain, and inter-domain contacts to the linker. LigE. (Mus musculus) PubMed

 23441.

The function and structure of Trm112 in archaea and its interaction network were studied using Haloferax volcanii as model system. Methyltransferases are also privileged Trm112 partners in archaea and this Trm112 network is much more complex than anticipated from eukaryotic studies. Trm112. (Mus musculus) PubMed

 23442.

LINC24065 was identified to have monoallelic expression in adult tissues[LINC24065] (Mus musculus) PubMed

 23443.

SbcC cleaves opposing strands of double-stranded DNA with different chemistries, leaving 3' and 5' phosphates respectively.[SbcC]SbcC cleaves opposing strands of double-stranded DNA with different chemistries, leaving 3' and 5' phosphates respectively.[SbcD] (Mus musculus) PubMed

 23444.

Lnczc3h7a promotes antiviral immune responses by facilitating the TRIM25-mediated ubiquitination of RIG-I, whereas non-self RNAs activate RIG-I and trigger innate immunity. (Mus musculus) PubMed

 23445.

protein transporter SprA has a distinctive architecture that uses an alternating access mechanism in which the two ends of the protein-conducting channel are open at different times [SprA] (Mus musculus) PubMed

 23446.

The Atg5, LC3-II and Bcl-2 mRNA expression is significantly increased and mRNA expression of P62 and Caspase-3 is significantly decreased in the human trophoblast cells infected with Brucella abortus mutant strain with deletion in VceA protein (2308DeltaVceA) than the wild type strain. P62 protein is scattered coloring and Cytochrome C protein is scarcely in the myometrium of 2308DeltaVceA infected mice. (Mus musculus) PubMed

 23447.

Aspergillus flavus protein PbsB is critical for growth and virulence in Aspergillus flavus, and lay a theoretical foundation for the prevention and control of Aspergillus flavus contamination. [PbsB] (Mus musculus) PubMed

 23448.

The results clearly indicate that the induction of AMT2-type ammonium transporter gene TaAMT2;3a may facilitates the nitrogen uptake from wheat leaves by Pst, thereby contribute to the infection of rust fungi. [AMT2;3a] (Mus musculus) PubMed

 23449.

MdFLP directly binds to the promoters of two auxin efflux carriers, MdPIN3 and MdPIN10, that are involved in auxin transport, activates their transcriptional expression, and thereby promotes the development of adventitious roots in self-rooted apple stocks.[FLP] (Mus musculus) PubMed

 23450.

QstR function is dependent on dimerization. Dimerization and function are c-di-GMP independent. Although ComEA is produced in a QstR-dependent manner, QstR-binding was not detected upstream of comEA suggesting the existence of a further regulatory pathway. QstR. (Mus musculus) PubMed

 23451.

This type of substrate specificity indicates that both the Pho15 of Candida albicans and the Pho15 of Candida parapsilosis may be a part of metabolic repair systems.[Pho15] (Mus musculus) PubMed

 23452.

This type of substrate specificity indicates that both the Pho15 of Candida albicans and the Pho15 of Candida parapsilosis may be a part of metabolic repair systems.[Pho15] (Mus musculus) PubMed

 23453.

these results indicate that CaSBP12 gene negative regulates the defense response against Phytophthora capsici infection which suggests their potentially significant role in plant defense. [CaSBP12] (Mus musculus) PubMed

 23454.

the Ml proteins studied form higher-order oligomers through their N-terminal region and that the same AT-rich site is recognized by MucR from Brucella abortus using a similar mechanism involving contacts with the minor groove of DNA and oligomerization.[MucR] (Mus musculus) PubMed

 23455.

these results indicate that Vtn acts as a bridge between the SSURE domains of PbsP on the group B streptococcus surface and host integrins to promote bacterial invasion of epithelial cells. . [PbsP] (Mus musculus) PubMed

 23456.

The deubiquitinase subunit Bre5 acts as a negative regulator of transcriptional factor Pdr1 transcriptional activity and behaves as a Candida glabrata-specific modulator of azole resistance. [Bre5], [Pdr1] (Mus musculus) PubMed

 23457.

Data demonstrate that it is an asymmetric dimer in solution. Initial rate experiments show hysteresis, which may be related to pathway regulation, and kinetic parameters similar to other bacterial isozymes. The enzyme binds two Zn(2+) ions and is not substrate inhibited. NagB adopts a novel dimeric structure in solution and shows kinetic parameters comparable to other Gram-positive isozymes. [NagA, NagB] (Mus musculus) PubMed

 23458.

Characterization of SpoIIIE slipping behavior reveals that individual motor subunits engage DNA upon ATP binding. Furthermore, the authors find that SpoIIIE's velocity exhibits an intriguing bi-phasic dependence on force. (Mus musculus) PubMed

 23459.

The results unraveled the involvement of PafBC in pafA transcription, and revealed the importance of proper PafA regulation in mycobacterial physiology. [PafA], [PafB], [PafC] (Mus musculus) PubMed

 23460.

[LAAD] Study made site-directed mutagenesis on surface-exposed hydrophobic residues of Proteus vulgaris L-amino acid deaminase (LAAD) insertion sequence (INS), and found that these mutations impaired the INS-membrane interaction but did not affect LAAD activity in the solution. Further found that when cell membrane is present, the catalytic activity can be increased by 8~10 folds for wild-type but not INS-mutated LAAD. (Mus musculus) PubMed

 23461.

The growth of pancreatic tumors in mice deficient for IL35 was significantly reduced. An analysis of tumor-infiltrating immune cells revealed a role for IL35 in the expansion of regulatory T cells and the suppression of CD4(+) effector T cells. [IL35] (Mus musculus) PubMed

 23462.

ThnR, thnD and thnE is required for immunity of B. thuringiensis to thurincin H, and thnI is not necessary for this response.[ThnR, thnD, thnE, thurincin H] (Mus musculus) PubMed

 23463.

Characterization of multicopper oxidase CopA from Pseudomonas putida KT2440 and Pseudomonas fluorescens Pf-5 [CopA] (Mus musculus) PubMed

 23464.

Characterization of multicopper oxidase CopA from Pseudomonas putida KT2440 and Pseudomonas fluorescens Pf-5 [CopA] (Mus musculus) PubMed

 23465.

the evidence indicates that activation of TRPV1 is a critical early step in a signaling mechanism that responds to a hyperosmotic stimulus, possibly lens shrinkage. By activating ERK1/2 and WNK, TRPV1 activation leads to NKCC1 phosphorylation and stimulation of NKCC1-mediated ion transport. (Mus musculus) PubMed

 23466.

Findings demonstrate that the HTLV-1 basic leucine zipper protein HBZ (HBZ) isoform levels are regulated at the step of translation initiation: [HBZ] (Mus musculus) PubMed

 23467.

biochemical and biophysical assays provided data highlighting the influence of solubilization and storage into L-asparaginase from Erwinia carotovora, structure, stability, and activity.[L-asparaginase] (Mus musculus) PubMed

 23468.

the Helicobacter pylori protein Csd5 promotes helical shape as part of a membrane associated, multi-protein shape complex that includes interactions with the periplasmic cell wall, a PG precursor synthesis enzyme, the bacterial cytoskeleton, and ATP synthase. [Csd5] (Mus musculus) PubMed

 23469.

Structural Dynamics of the MscL C-terminal Domain [MscL] (Mus musculus) PubMed

 23470.

High frequencies of uncommon mutations in rpoB gene by LPA were observed, highlighting possibility of those in-silico detected mutations that may not impart phenotypic resistance further. (Mus musculus) PubMed

 23471.

The results demonstrate that hpf is expressed independently of rpoN, and that hpf regulation includes both transcriptional and post-transcriptional processes, allowing the cells to produce sufficient HPF during stationary phase to maintain viability while dormant. [HPF] (Mus musculus) PubMed

 23472.

The bluE gene (locus tag RSP_0788) of Rhodobacter sphaeroides 2.4.1 is a putative functional homolog of the L-threonine kinase enzyme (PduX, EC 2.7.1.177) of Salmonella enterica. The RsBluE has L-Thr-independent ATPase activity in vivo and in vitro. [RsBluE] (Mus musculus) PubMed

 23473.

Role of the luxS gene in bacteriocin biosynthesis by Lactobacillus plantarum KLDS1.0391 [luxS] (Mus musculus) PubMed

 23474.

20 amino acid region located between positions 390 and 409 of CreA is critical for the rapid degradation of the carbon catabolite repressor CreA in Aspergillus oryzae. [CreA] (Mus musculus) PubMed

 23475.

characterization of mismatch-binding protein MutS1 and nicking endonuclease MutL from a euryarchaeon Methanosaeta thermophile [MutS1][MutL] (Mus musculus) PubMed

 23476.

The authors propose that the coupling of MreB filament alignment to shape-reinforcing peptidoglycan synthesis creates a locally-acting, self-organizing mechanism allowing the rapid establishment and stable maintenance of emergent rod shape.[MreB] (Mus musculus) PubMed

 23477.

HAN showed single-strand specific 3' to 5' exonuclease activity.HAN role in the replication fork repair.[HAN]HEF interacts with HAN at stalled replication fork.[HEF] (Mus musculus) PubMed

 23478.

chemoreceptor Mcp2 is involved in the sensing of xylem sap and constituents of xylem exudate, including methionine, serine and histidine, and plays an important role in epiphytic entry and virulence.[Mcp2] (Mus musculus) PubMed

 23479.

a gene (raxM) encodes a small protein, which functions as a regulator of raxX expression.[RaxM, RaxX] (Mus musculus) PubMed

 23480.

The overall results show that EhRho1 regulates phagocytosis by modulating actin dynamics through recruitment of EhFormin1 and EhProfilin1 at the phagocytosis nucleation site in Entamoeba histolytica.[EhRho1, EhFormin1, EhProfilin1] (Mus musculus) PubMed

 23481.

YWHAE is a new cellular partner of CagA. CagA enhances YWHAE-mediated transactivation of NF-kappaB. [CagA] (Mus musculus) PubMed

 23482.

small RNA binding but not slicer activity of MoAGO2 was essential for the ability to diminish the efficacy of RNA interference (MoAGO2). (Mus musculus) PubMed

 23483.

Mfd and DNA helicase UvrD in mutational processes in Pseudomonas putida [Mfd][UvrD] (Mus musculus) PubMed

 23484.

The SaCcpE-RD exhibits various citrate-binding-independent conformational changes at the contacting interface. The SaCcpE-RD prefers the dimeric state in solution, whereas the SaCcpE-FL prefers the tetrameric state. Our results provide insight into the molecular function of SaCcpE. (Mus musculus) PubMed

 23485.

acute calcemic response to PTH in vivo in mice lacking PTH receptors in osteocytes vs littermate controls, is resported.[Pthrp receptor] (Mus musculus) PubMed

 23486.

endonuclease domain of Bacillus subtilis MutL is functionally asymmetric [MutL] (Mus musculus) PubMed

 23487.

Hemagglutinin genetic variation in H1N1 virus in India.[hemagglutinin] Neuraminidase genetic variation in H1N1 virus in India.[[neuraminidase] (Mus musculus) PubMed

 23488.

AedaeCAPA-1 specifically inhibits secretion of larval and adult MTs stimulated by 5-HT and by the calcitonin-related diuretic hormone DH31, whilst having no activity on Malpighian tubules stimulated by other diuretic factors.[CAPA-] (Mus musculus) PubMed

 23489.

NuA4 acetyltransferase is required for efficient nucleotide excision repair in yeast [NuA4] (Mus musculus) PubMed

 23490.

Efg1 is required for early assembly and reorganization of the 5' domain of 18S rRNA (Efg1). (Mus musculus) PubMed

 23491.

HVR1 physical-chemical properties are strongly associated with HIV co-infection.[HVR1] (Mus musculus) PubMed

 23492.

The protein binding study identified the association of host protein Polypyrimidine tract binding protein and associated splicing factor (PSF) with HIV-1 integrase. Thus our study emphasizes the negative influence of PSF on HIV-1 replication [integrase]. (Mus musculus) PubMed

 23493.

near-atomic-resolution cryo-electron microscopy structures for feline calicivirus both undecorated and labelled with a soluble fragment of its cellular receptor, feline junctional adhesion molecule A; VP2, a minor capsid protein encoded by all caliciviruses, forms a large portal-like assembly at a unique three-fold axis of symmetry, following receptor engagement [VP2] (Mus musculus) PubMed

 23494.

dfrA35 is a trimethoprim resistance gene in E. coli isolated from calves [dfrA35] (Mus musculus) PubMed

 23495.

In this report, we identify SsdA as an important component of trehalose and fungal cell wall biosynthesis in A. fumigatus that consequently impacts the host immune response and fungal virulence in animal models of infection [SsdA]. (Mus musculus) PubMed

 23496.

Further biochemical studies revealed that Vibrio parahaemolyticus VpadF mainly relies on the C-terminal region for type I collagen binding and Vibrio parahaemolyticus MAM7 relies on mce domains to bind to type I collagen.[VpadF, MAM7] (Mus musculus) PubMed

 23497.

Pathway analysis of the transcriptome indicated that cellular processes related to the central nervous system (e.g., neurogenesis, synaptic plasticity, glial cell development) and immune functions (e.g., immune system activation, leukocyte function, macrophage response) were preferentially modulated by secretogranin II-derived neuropeptide secretoneurin A. [secretogranin II] (Mus musculus) PubMed

 23498.

the proline/arginine-rich motif is required for efficient type III-dependent secretion and translocation of XopB and determines the dependence of XopB transport on the general type III secretion chaperone HpaB.[HpaB] (Mus musculus) PubMed

 23499.

JH III indirectly activates Vg expression by interfering with or inhibiting the phosphorylation of nuclear proteins bound to Vg1HRE. Involvement of JH III in both induction of Vg1 and control of nuclear proteins binding to Vg1HRE suggest the latter to play an important role in JH signaling. (Mus musculus) PubMed

 23500.

Kaposi's sarcoma-associated herpesvirus SOX binds to LIMD1 and shows RNA substrate selectivity [SOX] (Mus musculus) PubMed

 23501.

Deletion of CgAzf1 resulted in decreased melanin production, reduced conidiation and increased hydrophilicity of aerial mycelium. [CgAzf1] (Mus musculus) PubMed

 23502.

structural analysis of NExo, an enzyme from Neisseria meningitidis that is specialized in the removal of the 3'-phosphate and other 3'-lesions, which are potential blocks for DNA repair (NExo) (Mus musculus) PubMed

 23503.

An extremely low Cd mutant lcd1 was isolated and identified using MutMap and RNA-seq. A Pro236Leu amino acid substitution in the highly conserved region of OsNRAMP5 is likely responsible for low Cd accumulation in the lcd1 mutant.[NRAMP5] (Mus musculus) PubMed

 23504.

This study characterized the poplar NF-YB gene family and confirmed the function of the PtNF-YB1 regulate flowering timing. At the same time, we found that the function of PtNF-YB1 to improve early flowering can overcome species barriers. (Mus musculus) PubMed

 23505.

The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor which form a unique ATP- and DNA-binding helicase fold with specific helicase motifs (H-subunit of the restriction endonuclease CglI) (Mus musculus) PubMed

 23506.

Transcriptomic data revealed that RpaA is mainly involved in the regulation of genes related to CO2 - acclimation in the light and to carbon metabolism in the dark.[RpaA] (Mus musculus) PubMed

 23507.

The RNA-splicing endonuclease has constrained substrate specificity (RNA-splicing endonuclease alpha and RNA-splicing endonuclease beta). (Mus musculus) PubMed

 23508.

Here, the authors identified Legionella pneumophila Lpw27461 as a new nuclear-localised effector that we have termed SnpL. Protein interaction studies showed that SnpL bound to the central Kyprides, Ouzounis, Woese motif region of SUPT5H. Ectopic expression of SnpL led to massive upregulation of host gene expression and macrophage cell death.[SnpL] (Mus musculus) PubMed

 23509.

PARS11 (Partner of SPO11) is required for both the DSB formation and ATR-dependent control of DSB number [PARS11] (Mus musculus) PubMed

 23510.

Hippo has a role in suppressing IRS2/AKT signaling prevents hepatic steatosis and liver cancer in a mouse model [hippo] (Mus musculus) PubMed

 23511.

absence of the RecN protein suppresses the cellular defects of Deinococcus radiodurans irradiated cells devoid of the PprA protein by limiting recombinational repair of DNA lesions [RecN][PprA] (Mus musculus) PubMed

 23512.

These results suggest the possibility that loss of BabA expression is not driven by adaptive immunity or toll-like receptor signaling, and that BabA may have other, unrecognized functions in addition to serving as an adhesin that binds Le(b). (Mus musculus) PubMed

 23513.

Lmp1 exists as distinct, region-specific, and lower molecular mass polypeptides encompassing 1 or more domains, including independent N-terminal and middle regions and a combined middle and C-terminal region. These polypeptides originate from complex posttranslational maturation events, partly supported by a periplasmic serine protease termed as BbHtrA.[Lmp1, BbHtrA] (Mus musculus) PubMed

 23514.

the miR394-LC4 module mediates auxin effects important for determining rice leaf inclination and architecture.[miR394, LC4] (Mus musculus) PubMed

 23515.

Prediction of the mechanism by which PfuEndoQ recognizes a deaminated base in double-stranded DNA (dsDNA) and cleaves the phosphodiester bond 5' from the lesion site (PfuEndoQ). (Mus musculus) PubMed

 23516.

CaMYB31 is a candidate gene for Pun3, which may act as a master regulator of capsaicinoid biosynthetic genes in pepper.[CaMYB31] (Mus musculus) PubMed

 23517.

a 1.55 A resolution structure of MtDPPS in complex with the substrate analogues geranyl S-thiodiphosphate (GSPP) and isopentenyl S-thiodiphosphate bound to their respective sites in one subunit, is reported.[MtDPPS] (Mus musculus) PubMed

 23518.

three copies of TaSnRK2.9 were isolated from chromosomes 5A, 5B and 5D of wheat (Triticum aestivum L.).[TaSnRK2.9-5A] (Mus musculus) PubMed

 23519.

Results suggest that sodB is important for normal physiological function, oxidation resistance and virulence in V. alginolyticus (sodB). (Mus musculus) PubMed

 23520.

results define viral poxins as a family of 2',3'-cGAMP-specific nucleases and demonstrate a mechanism for how viruses evade innate immunity [B2R] (Mus musculus) PubMed

 23521.

a heat shock transcription factor that improves thermotolerance in Arabidopsis thaliana - [Hsf05] (Mus musculus) PubMed

 23522.

overexpression gene alters endosperm starch content and composition - [bZIP22] (Mus musculus) PubMed

 23523.

a Ycf54 domain-containing protein that affects chlorophyll biosynthesis - [CS3] (Mus musculus) PubMed

 23524.

altered expression differentially regulates tillering and grain yield - [NPF7.1 and NPF7.4] (Mus musculus) PubMed

 23525.

multiple roles in modulating plant height, panicle branching and grain shape - [miR535] (Mus musculus) PubMed

 23526.

employed by HY5 increases anthocyanin accumulation via repression of MYB16/308 - [MYBDL1] (Mus musculus) PubMed

 23527.

functional identification in biotic stress - [HIR4] (Mus musculus) PubMed

 23528.

important for regulation of hyphal growth, appressorial development, penetration, pathogenicity, conidiation, intracellular cAMP level, and stress tolerance - [CAP] (Mus musculus) PubMed

 23529.

These studies demonstrated that IL-1beta is produced during Group A Streptococcus skin infection in a Streptolysin S-dependent manner.[Streptolysin S] (Mus musculus) PubMed

 23530.

Altogether these data suggest that EhSyf is a bona fide Syf1 ortholog involved in transcription and splicing.[EhSyf] (Mus musculus) PubMed

 23531.

Study found that DR0846 is a PrxQ with two cysteine residues at positions 60 and 65. Additionally, DR0846 exhibits a dual function as a peroxidase and a molecular chaperone. These results suggest that DR0846 contributes to resistance against oxidative and heat stresses in D. radiodurans. [DR0846] (Mus musculus) PubMed

 23532.

We present the identification and initial characterization of a putative homologue of the SAC1 phosphoinositide phosphatase family. Our results show that the protein is expressed throughout the asexual blood stages and that it localises to the endoplasmic reticulum and potentially to the Golgi apparatus. (Mus musculus) PubMed

 23533.

This study describes the use of in vitro assays to characterize the three glycosyltransferase modules of the protein designated WbbB from Klebsiella pneumoniae O12. This protein combines key activities necessary to synthesize the O antigenic polysaccharide portion of lipopolysaccharide. [WbbB] (Mus musculus) PubMed

 23534.

ZmAPRG functions as an upstream regulation node, directly or indirectly regulating APases, protein phosphatases, and phosphate transporter genes involved in Pi metabolism and utilization in maize.[ZmAPRG] (Mus musculus) PubMed

 23535.

sodA and sodB complement each other and cooperate in the process of intracellular survival of bacteria to protect against ROS damage [sodA; sodB]. (Mus musculus) PubMed

 23536.

Results demonstrate that TRIM23 gene plays an important role in innate immune regulation and provide new insights into understanding the functional characteristics of the TRIM23 in teleosts [TRIM23]. (Mus musculus) PubMed

 23537.

The study suggests that SMG1 is involved in other quality control pathways, affecting DNA repair and the unfolded protein response, in addition to its role in mRNA quality control (SMG1). (Mus musculus) PubMed

 23538.

a cytochrome P450 gene, MoMCP1, involving the alleviation of manganese toxin and pathogenicity, was identified.[MoMCP1] (Mus musculus) PubMed

 23539.

The complete coding sequence of CgRunx was of 1638 bp encoding a predicted polypeptide of 545 amino acids with one conserved runt domain, which shared high similarity with other reported Runx proteins. CgRunx was highly expressed in hemocytes, gill and mantle both at the protein and nucleic acid levels.[Runx] (Mus musculus) PubMed

 23540.

These findings indicate a positive regulatory role for ZmOST1 in guard cell abscissic acid signaling and drought response in maize plants.[ZmOST1] (Mus musculus) PubMed

 23541.

Staphylococcus aureus requires the GraXRS regulatory system for growth within the highly acidic macrophage phagolysosome. PH-dependent induction of antimicrobial peptide resistance requires the expression of GraS sensor kinase. In murine models of infection, GraS plays an important role for bacterial survival in the acute stages of systemic infection within liver-resident Kupffer cells. (Mus musculus) PubMed

 23542.

The data presented here are consistent with an earlier study that demonstrated that PlzA plays an essential role in spirochete survival in the mammalian environment. We add to our understanding of the c-di-GMP regulatory network by demonstrating that while PlzB binds c-di-GMP, it is not functionally synonymous with PlzA. The absence of plzB from most strains suggests that it is not required for survival.[PlzB] (Mus musculus) PubMed

 23543.

All these data disclose the relevance of the only one DNA ligase (EhDNAligI) as a specialized and unique ligase in Entamoeba histolytica that may be involved in DNA repair of the 8-oxoG lesions.[EhDNAligI] (Mus musculus) PubMed

 23544.

EndoMS/NucS is a mismatch-specific endonuclease that works cooperatively with the sliding clamp of the replisome to correct replication errors (EndoMS/NucS). (Mus musculus) PubMed

 23545.

Deletion of the RrrR(+) gene resulted in significantly impaired biofilm formation, while its overproduction increased biofilm yield (RrrR). (Mus musculus) PubMed

 23546.

SAMHD1 can suppress the proliferation of grass carp reovirus (GCRV) in CIK cells [SAMHD1]. (Mus musculus) PubMed

 23547.

[CelA,CelB] cellulase catalytic domain and cellulose-binding domain of CelA together were sufficient for both cellulase activity and wilting in tomato. celB, carries a single-base deletion in most C. michiganensis strains but does not carry a functional signal peptide in its N terminus, so an experimentally modified CelB protein with a CelA signal peptide was secreted and able to cause wilting in tomato (Mus musculus) PubMed

 23548.

Aspartic protease saposin-like domain active structure is an open saposin fold dimer whose formation is pH-dependent.[aspartic protease] (Mus musculus) PubMed

 23549.

reconstitution and cryoelectron microscopy of the Rubisco-CcmM complex [CcmM] (Mus musculus) PubMed

 23550.

EndoMS/NucS (CglEndoMS) homodimers showed a mismatch-specific endonuclease activity that was markedly stimulated by the beta-clamp encoded by dnaN in vitro (EndoMS/NucS). (Mus musculus) PubMed

 23551.

The newly identified lncRNA MAR1 acts as a miR-487b sponge to regulate Wnt5a protein, resulting in promoting muscle differentiation and regeneration. MAR1 could be a novel therapeutic target for treating muscle atrophy induced by either aging or mechanical unloading. [lnc RNA muscle anabolic regulator 1 (MAR1)] (Mus musculus) PubMed

 23552.

A noncanonical function of MutL that promotes chromosomal deletions through non-homologous end joining to prevent phage predation (MutL). (Mus musculus) PubMed

 23553.

Functional interplay in vitro between P. furiosus PCNA and enzymatic functions of the Mre11-Rad50 complex in the DNA end resection process (PCNA). (Mus musculus) PubMed

 23554.

A structural model is proposed to explain N6-threonylcarbamoyladenosine (t6A) synthesis by the TsaB/TsaD/TsaE complex (TsaB/TsaD/TsaE). (Mus musculus) PubMed

 23555.

deletion the C-terminal segment of VhPLD improved its interfacial binding properties to different phospholipid monolayers [phospholipase d] (Mus musculus) PubMed

 23556.

[BDSF] BDSF is the predominant in-planta QS signal used during X. campestris pv. campestris infection (Mus musculus) PubMed

 23557.

a novel function for a Lotus japonicus ALOG (Arabidopsis LSH1 and Oryza G1) family member, LjALOG1, involved in positively regulating nodulation, is identified.[LjALOG1] (Mus musculus) PubMed

 23558.

Data report a complete maize male sterile mutant male sterile 6021 (ms6021), which shows defective anther cuticle and exine development. The expression pattern analysis showed that MS6021 was specifically expressed in the tapetum and microspore after meiosis, and MS6021 was mainly localized to the plastid via the N-terminal transit peptide. This gene function as a fatty acyl-ACP reductase. [ms6021] (Mus musculus) PubMed

 23559.

Here, the authors describe two novel regulators, CJJ81176_0275 and CJJ81176_0276 (designated as CheP and CheQ), which specifically activate the transcription of the chemotaxis core genes cheV, cheA and cheW in Campylobacter jejuni and they are also essential for chemotactic responses.[CheP, CheQ] (Mus musculus) PubMed

 23560.

TFS (TFIIS in Eukarya) and the Spt4-Spt5 complex are universally encoded in archaeal genomes, and here the authors demonstrate that both elongation factors, via different mechanisms, can accelerate transcription through archaeal histone-based chromatin.[TFS, Spt4, Spt5] (Mus musculus) PubMed

 23561.

the current study demonstrated that HOXA11-AS promoted cell proliferation and metastasis by increasing the activity of TGFbeta1 in CFs, which further identified the specific role of HOXA11-AS in cardiac fibrosis. (Mus musculus) PubMed

 23562.

DENV2 envelope protein (E) directly interacted with beta3 integrin, and their interacting sites were located at domain III of E protein (EDIII) [E protein]. (Mus musculus) PubMed

 23563.

ComM is a hexameric helicase that promotes branch migration during natural transformation (ComM). (Mus musculus) PubMed

 23564.

[Arb93B] Arb93B enhances plant disease susceptibility by suppressing ROS-associated plant defense responses (Mus musculus) PubMed

 23565.

These data collectively indicated that MoHrip1 is necessary for fungal penetration and invasive expansion, and further full virulence of rice blast fungus.[MoHrip1] (Mus musculus) PubMed

 23566.

RNA-binding protein RBP-P is required for glutelin and prolamin mRNA localization in the endosperm cells.[RNA-binding protein RBP-P] (Mus musculus) PubMed

 23567.

These results suggested the favorable allelic variation TaPPH-7A-1 (A) should be valuable in enhancing grain yield by improving the source (chlorophyll content) and sink (the developing grain) simultaneously. Furthermore, the newly developed molecular marker TaPPH-7A-dCAPS could be integrated into a breeding kit of screening high TGW wheat for marker-assisted selection.[PPH-7A] (Mus musculus) PubMed

 23568.

Transient expression of a JcHDZ16-YFP fusion protein in Arabidopsis protoplasts cells showed that JcHDZ16 is localized in the nucleus. In addition, rice seedlings transgenically expressing JcHDZ16 had lower proline contents and activities of antioxidant enzymes together with higher relative electrolyte leakage and malondialdehyde contents under salt stress conditions.[HDZ16] (Mus musculus) PubMed

 23569.

there is a strong association between llsX and the invasiveness of L. monocytogenes in HEp-2 cells [llsX ]. (Mus musculus) PubMed

 23570.

Here, the authors show that Toxoplasma gondii DrpC (TgDrpC) localizes to cytoplasmic puncta; however, in dividing parasites, TgDrpC redistributes to the growing edge of the daughter cells. By conditional knockdown, they determined that loss of TgDrpC stalls division and leads to rapid deterioration of multiple organelles and the inner membrane complex. (Mus musculus) PubMed

 23571.

PvNod22 has a nonredundant function during legume-rhizobia symbiosis associated with infection thread elongation, likely by sustaining protein homeostasis in the ER. (Mus musculus) PubMed

 23572.

This study identified a visible fimbria-like protein, SssP1, participating in adhesion to host cells and contributing to the virulence in S. suis.[Sssp1] (Mus musculus) PubMed

 23573.

ONAC066 is a nucleus-localized transcription activator that can respond to multiple abiotic stress factors. Functional analyses using overexpression and RNAi-mediated suppression transgenic lines demonstrate that ONAC066 is a positive regulator of drought and oxidative stress tolerance in rice.[ONAC066] (Mus musculus) PubMed

 23574.

Over-expression of RLK-V1.1 could trigger cell death in Nicotiana benthamiana, and RLK-V1.1 transgenic wheat accumulated more reactive oxygen species and displayed a stronger hypersensitive response than did the recipient, which led to enhanced blumeria graminis resistance.[RLK-V1.1] (Mus musculus) PubMed

 23575.

Oxalyl coenzyme A decarboxylase-1 role in oxalate degradation and endosperm development.[Oxalyl coenzyme A decarboxylase-1] (Mus musculus) PubMed

 23576.

FLS is a bifunctional 2-oxoglutarate-dependent dioxygenase and functions in flavonol production in planta. [FLS] (Mus musculus) PubMed

 23577.

[mgl2] deletion of the mgl2 gene resulted in disturbances in biofilm formation and a slight increase in motility in minimal medium (Mus musculus) PubMed

 23578.

[PrtA] prtA is the solely responsible gene for the extracellular protease activity detected from this bacterium (Mus musculus) PubMed

 23579.

The Oryza sativa CHLOROPLAST VESICULATION (CV)-mediated chloroplast degradation pathway is involved in the regulation of nitrogen assimilation during stress-induced plant senescence.[CV] (Mus musculus) PubMed

 23580.

The knockdown of MKK6 by RNA interference technology altered the expression levels of some antioxidant genes. In addition, the knockdown of (MAP Kinase Kinase 6) MKK6 resulted in increased malonyldialdehyde (MDA) concentration and decreased antioxidant-related enzymes activity in honeybees. [MKK6] (Mus musculus) PubMed

 23581.

role in regulation of some genes associated with chlorophyll biosynthesis and photosynthesis at low temperatures - [TCM12] (Mus musculus) PubMed

 23582.

Ail can provide serum resistance via multiple mechanisms and recruitment of vitronectin, factor H, and C4BP is largely dispensable for Ail-mediated serum resistance.[Ail] (Mus musculus) PubMed

 23583.

Optimizes Light-Activated Heterotrophic Growth - [NdbA] (Mus musculus) PubMed

 23584.

PtDXS is a key enzyme in terpenoid biosynthesis.[PtDXS] (Mus musculus) PubMed

 23585.

class A1 scavenger receptor (SR-A1) SR-A1 may be a pivotal element for the anti-inflammation effect of insulin in macrophages. (Mus musculus) PubMed

 23586.

These results indicate that the phosphatase MoPtp2p is involved in the regulation of MoHog1p phosphorylation and that overexpression of the gene MoPTP2 is a novel molecular mechanism of fungicide resistance.[PTP2] (Mus musculus) PubMed

 23587.

The authors conclude that EipA is a molecular determinant of Brucella virulence that functions to maintain cell envelope integrity and influences cell division.[EipA] (Mus musculus) PubMed

 23588.

Collectively, these data suggest that UzcRS functions as the core-signaling unit within a multicomponent signal transduction pathway that includes a diverse set of auxiliary regulators, providing further insight into the complexity of signaling networks[UczRS] (Mus musculus) PubMed

 23589.

Deletion of pilA2 caused loss of twitching motility, whereas deletion of pilA1 did not influence twitching motility but caused hyperpiliation and extended distribution of type IV pili along the sides of the cell.[pilA1,pilA2] (Mus musculus) PubMed

 23590.

The HicA toxin contains a double-stranded RNA-binding domain that is essential for RNA recognition and that the C-terminus of the HicB antitoxin folds into a ribbon-helix-helix DNA-binding motif. The active site of HicA is sterically blocked by the N-terminal region of HicB (HicA and HicB). (Mus musculus) PubMed

 23591.

OprBXo is not only essential for chemotaxis and stress tolerance, but also for motility, biofilm formation and exopolysaccharide production, which may contribute to the virulence of Xanthomonas oryzae pv. oryzae.[OprBXo] (Mus musculus) PubMed

 23592.

acts as a triacylglycerol lipase and plays a role in triacylglycerol homeostasis - [LIP4] (Mus musculus) PubMed

 23593.

The authors show that cryptic interaction sites play a key role in recruiting DnaD and DnaB proteins by DnaA to function as adaptors to assist in DNA helicase loading for DNA replication and they map these regions for the entire pathway.[DnaA, DnaB, DnaD] (Mus musculus) PubMed

 23594.

CXCL8-signaling is a prominent and distinctive feature of abdominal aortic aneurysm (AAA), interference with the pathway constitutes a promising target for medical stabilization of AAA [CXCL8]. (Mus musculus) PubMed

 23595.

Our data highlight a protective role of Plin5 against hepatic lipotoxic injuries induced by HCV NS5A, which is helpful for understanding the steatosis and injuries in liver during HCV infection. (Mus musculus) PubMed

 23596.

The spoIIID deletion mutant Bacillus thuringiensis HD73 strain exhibited no mother cell lysis in Schaeffer's sporulation medium (SSM) but did in (1/2) Luria-Bertani (LB) medium. (Mus musculus) PubMed

 23597.

In conclusion, this study elucidates the importance of TonB1, TonB2 and TonB3 in iron acquisition and virulence of Aeromonas hydrophila, which lays the foundation for future studies regarding the survival mechanisms of this bacterium in iron-restricted environments.[ TonB1, TonB2, TonB3] (Mus musculus) PubMed

 23598.

SodA1 can either rescue or support SodA2 when SodA2 is defective or insufficiently potent. The presence of two MnSODs gives S. maltophilia an advantage against superoxide stress. (Mus musculus) PubMed

 23599.

CXE1 expression is associated with catabolism of volatile acetate esters in peach fruit. [CXE1] (Mus musculus) PubMed

 23600.

Here, the authors identified two small RNAs, FnrS and ArcZ, which repress hilD translation, leading to decreased production of HilA. FnrS and ArcZ are oppositely regulated in response to oxygen, one of the key environmental signals affecting expression of Salmonella pathogenicity island 1.[FnrS, ArcZ, hilD] (Mus musculus) PubMed

 23601.

Selection for Dry gene mutations was a major step leading to the origin of sweet sorghum.Dry gene encodes NAC transcription factor.[dry] (Mus musculus) PubMed

 23602.

The integral membrane proteins glucose transporter-2 and -5 (GLUT-2 and GLUT-5) that facilitate the transport of hexoses across epithelial cell layers that separate distinct compartments in organism were detected in the chicken intestinal epithelial cells using immunohistochemical labeling with polyclonal primary antibodies.[GLUT5] (Mus musculus) PubMed

 23603.

The authors show that activation of the RES toxin in vivo causes a depletion of intracellular NAD(+) levels eventually leading to inhibition of cell growth in Escherichia coli and inhibition of global macromolecular biosynthesis.[RES] (Mus musculus) PubMed

 23604.

Together, these results suggest that DdcA acts by helping to set a threshold of YneA required to establish the cell cycle checkpoint, uncovering a new regulatory step controlling activation of the DNA damage checkpoint in Bacillus subtilis.[DdcA, YneA] (Mus musculus) PubMed

 23605.

The authors show that antigenic variation of VlsE in B31 and JD1 is highly similar, despite the lack of 17 bp direct repeats in JD1, a somewhat different arrangement of the silent cassettes, divergent inverted repeat sequences and general divergence in the vls sequences.[VlsE] (Mus musculus) PubMed

 23606.

These results suggest that ParA modulates DivIVA activity. Thus, the authors demonstrate that the ParA-DivIVA interaction facilitates chromosome segregation and modulates cell elongation.[ParA] (Mus musculus) PubMed

 23607.

The results indicated that TFB3 activates the expression of DNA damage response (DDR) genes by interaction with other transcriptional factors at the promoter regions of DDR genes to facilitate the formation of transcription initiation complex (TFB3). (Mus musculus) PubMed

 23608.

Results demonstrate that the transmembrane helix of TcpP plays an important role in regulating TcpP transcription activity in response to its positive effectors [TcpP]. (Mus musculus) PubMed

 23609.

HAF1 mediates the ubiquitination and proteasomal degradation of ELF3.HAF1 maintains the circadian rhythm of ELF3 accumulation.ELF3 is genetically epistatic to HAF1.[HAF1][ELF3] (Mus musculus) PubMed

 23610.

BZIP22 is an endosperm-specific transcription factor.BZIP22 regulates 27-kD gamma-zein gene expression during endosperm development.[BZIP22] (Mus musculus) PubMed

 23611.

In this study, the authors present evidence that single amino acid proline substitutions produce two different conformers of the membrane anchor domain of YadA; one with the N-termini facing the extracellular surface, and a second with the N-termini located in the periplasm. They propose that trimeric autotransporter adhesins adopt a hairpin intermediate during secretion.[YadA] (Mus musculus) PubMed

 23612.

Analysis of the ability of these mutant strains to promote epithelial cell proliferation in vivo demonstrated that the pilin subunit, TadE, is the bifidobacterial molecule responsible for this proliferation response and imply that bifidobacterial Tad pili may contribute to the maturation of the naive gut in early life.[TadE] (Mus musculus) PubMed

 23613.

[dctP] Inactivation of dctP in A. brasilense led to a drastic reduction in its ability to grow on dicarboxylates and form cell aggregates (Mus musculus) PubMed

 23614.

MYB1 is involved in positive regulation of apigenin metabolism in celery.[MYB1] (Mus musculus) PubMed

 23615.

disruption of OsLHT1 significantly inhibited the rice growth and fecundity (LHT1) (Mus musculus) PubMed

 23616.

the zinc finger protein Zfp1 is essential for fungal sporulation and virulence in C. neoformans (Zfp1) (Mus musculus) PubMed

 23617.

PINA inhibits the unwinding activity of Hjm and both proteins work together remodeling replication forks and promote Holliday junction migration (PINA, Hjm). (Mus musculus) PubMed

 23618.

plays a crucial role in resistance to multiple pathogens - [BSR1] (Mus musculus) PubMed

 23619.

TaZIM-A1, an atypical GATA-like transcription factor, is a negative regulator of flowering in wheat.[TaZIM-A1] (Mus musculus) PubMed

 23620.

structural features and chromosome-specific rRNA gene expression - [Nor-B1 and Nor-B2] (Mus musculus) PubMed

 23621.

These results indicate that ArlRS plays a strong role in regulating oxacillin resistance in MRSA strains, which involves direct modulation of spx expression.[ArlS, ArlR, spx] (Mus musculus) PubMed

 23622.

CYP71Z18 has a role in elevated blast resistance in transgenic rice [CYP71Z18] (Mus musculus) PubMed

 23623.

GhWRKY22 acts as a transcriptional repressor to regulate anther/pollen development possibly by modulating the expression of the JAZ genes. [GhWRKY22] (Mus musculus) PubMed

 23624.

AcpB is a much better acceptor of acyl chains from acyl-phosphates than is AcpA. [AcpB; AcpA] (Mus musculus) PubMed

 23625.

E. rhusiopathiae CbpB was located on the cell surface of E. rhusiopathiae. Moreover, CbpB exhibited binding activity to porcine endothelial cells. Recombinant CbpB successfully bound to host plasminogen but was unable to bind to fibronectin.[CbpB] (Mus musculus) PubMed

 23626.

mcr-9 is capable of conferring phenotypic resistance to colistin in Salmonella enterica Serotype Typhimurium [mcr-9] (Mus musculus) PubMed

 23627.

We showed that MICU1 and -2 do not act as gatekeepers at low [Ca(2+)]cyt but are essential for normal growth, host cell invasion, and intracellular replication, revealing lineage-specific adaptations [MICU1; MICU2]. (Mus musculus) PubMed

 23628.

a R2R3-MYB transcription factor that is involved in fruit ripening through modulation of starch degradation by repressing starch degradation-related genes and MabHLH6 - [MYB3] (Mus musculus) PubMed

 23629.

required for fiber development via maintaining dynamic F-actin cytoskeleton and modulating cellulose biosynthesis -[XLIM6] (Mus musculus) PubMed

 23630.

the global transcriptional regulator HpaR1 influences many of the same genes as another global regulator Clp, including the engXCA gene that encodes extracellular endoglucanase.[engXCA, HpaR1, Clp] (Mus musculus) PubMed

 23631.

cdkn2ab acts as a potent tumor suppressor gene in fish melanoma models.[Cdkn2ab] (Mus musculus) PubMed

 23632.

cdkn2ab acts as a potent tumor suppressor gene in fish melanoma models.[Cdkn2ab] (Mus musculus) PubMed

 23633.

These studies provide evidence for ChAcs1 as a key regulator governing lipid metabolism, carbon source utilization and virulence of this hemibiotrophic fungus.[ChAcs1] (Mus musculus) PubMed

 23634.

IL-32epsilon induces caspase-independent apoptosis mediated by N-Myc interactor in macrophages infected with Mycobacterium tuberculosis. [IL32] (Mus musculus) PubMed

 23635.

GhWOX13 genes may influence cotton fiber development (GhWOX13) (Mus musculus) PubMed

 23636.

The results suggest that Lys racemase contributes to production of D-Lysine and D-Alanine for use as peptidoglycan components, and that Diaminopimelate epimerase converts LL-diaminopimelate to meso-diaminopimelate, a precursor in the L-Lysine biosynthetic pathway. [Lysine racemase] (Mus musculus) PubMed

 23637.

a growth regulator that functions through elevating expression of transporter genes for multiple metals - [TITANIA] (Mus musculus) PubMed

 23638.

FenA assimilates three manganese ions (its preferred metal cofactor) in the active site and all three metals are essential for FenA nuclease activity (FenA). (Mus musculus) PubMed

 23639.

[gGT] compared mice showing similar bacterial load after infection with gGT-proficient or gGT-deficient H. pylori to analyse the specific role of the enzyme during infection. H. pylori gGT supports initial colonization. Nevertheless, bacteria lacking gGT can still colonize and persist. Presence of gGT during infection favoured a proinflammatory innate and adaptive immune response. (Mus musculus) PubMed

 23640.

[Emp] Using multidisciplinary approaches, including circular dichroism (CD) and Fourier transform infrared (FTIR) spectroscopy, transmission electron (TEM) and immunogold transmission electron microscopy, functional ELISA assays and in silico techniques, study characterized the Emp protein; demonstrated that Emp and its truncated forms bind to suprastructures in human skin, cartilage or bone. (Mus musculus) PubMed

 23641.

Orc1-2 functions as a global regulator in the DNA damage response network of S. islandicus (Orc1-2). (Mus musculus) PubMed

 23642.

Wnt binding instead eliminates synapses by inducing Frizzled's endocytosis and the downregulation of neurexin[gamma-Neurexin and Frizzled] (Mus musculus) PubMed

 23643.

Structural basis of phosphatidic acid sensing by APH in apicomplexan parasites has been presented. [APH] (Mus musculus) PubMed

 23644.

Structural basis of phosphatidic acid sensing by APH in apicomplexan parasites has been presented. [APH] (Mus musculus) PubMed

 23645.

Mapping of 503 transcripts directly bound by RsmN in P. aeruginosa. About 200 of the mRNAs identified encode proteins of demonstrated function including some determining acute and chronic virulence traits. (Mus musculus) PubMed

 23646.

A unique upstream open reading frame (uORF) found only in var2csa 5' UTR plays a key role in determining the cellular localization of the downstream open reading frame -encoded protein.[var2csa] (Mus musculus) PubMed

 23647.

functional characterization of the anserinase from Oreochromis niloticus [anserinase] (Mus musculus) PubMed

 23648.

Stereoselective catalysis controlled by a native leucine or variant isoleucine wing-gatekeeper in 2-haloacid dehalogenase. (Mus musculus) PubMed

 23649.

[Ya81] Comparative analysis of other stripe rust resistance genes located in chromosome 6A led to the formal designation of YrAW5 as Yr81 (Mus musculus) PubMed

 23650.

A structurally conserved motif in uracil-DNA glycosylase elicits duplex nucleotide-flipping the DNA double helix (uracil-DNA glycosylase). (Mus musculus) PubMed

 23651.

This work reveals the importance of the MyoE tail domain and its phosphorylation/dephosphorylation in the growth and morphology of A. fumigatus.[MyoE] (Mus musculus) PubMed

 23652.

AtlA-SS autolysin modulates bacterial chain length, and contributes to the full virulence of Streptococcus suis during infection [AtlA] (Mus musculus) PubMed

 23653.

Crystal structure of an unusual single-stranded DNA-binding protein encoded by Staphylococcal cassette chromosome elements has been described. [LP1413] (Mus musculus) PubMed

 23654.

Pof1 and Pof3, are required for downregulating Wee1 and are possibly responsible for recruiting Wee1 to Skp1/Cul1/F-box protein ubiquitin E3 ligase complex.[Pof3, Pof1, Wee1] (Mus musculus) PubMed

 23655.

A linker region containing a caspase-3 cleavage motif separates the two functional domains of Salmonella-induced filament A protein (SifA). Processing of SifA by caspase-3 at this particular site is required for function and proper localization of the effector protein domains. Each of the SifA functional domains following caspase-3 cleavage locates to different subcellular locations. (Mus musculus) PubMed

 23656.

a short stretch of hydrophobic residues (VLLVL) in the center of TdIF2/ERBP acted as a nucleolar exclusion signal, which reduced the nucleolar accumulation of mCherry-NoLS fusion proteins [TDIF2] (Mus musculus) PubMed

 23657.

crystal structure of an archaeal NCX [NCX] (Mus musculus) PubMed

 23658.

WSL6 is essential for chloroplast ribosome biogenesis during early chloroplast development in rice [WSL6] (Mus musculus) PubMed

 23659.

An extracytoplasmic function (ECF) sigma factor, DdvS, drives the expression of all the cas genes as well as of the CRISPR array of a type III-B CRISPR-Cas system in M. xanthus (DdvS). (Mus musculus) PubMed

 23660.

TgROP18 targets the purinergic receptor P2X1 of the SF268 human neural cells and inhibits ATP-induced apoptosis through the mitochondrial pathway [TgROP18]. (Mus musculus) PubMed

 23661.

an aquaporin involved in boron homeostasis and abiotic stress - [COLD1] (Mus musculus) PubMed

 23662.

silencing of lncRNA SOX21-AS1 could act to alleviate neuronal oxidative stress and suppress neuronal apoptosis in Alzheimer's disease mice.[lncRNA SOX21-AS1] (Mus musculus) PubMed

 23663.

Optimized specific enzyme activity of MPH was 5.26 U/mg under 35 degrees C and pH 11.0 conditions when methyl parathion as the substrate. [MPH] (Mus musculus) PubMed

 23664.

the QTL Qfhs.ifa-5A interval contains two resistance QTL associated with anther extrusion and Fusarium head blight resistance [Qfhs.ifa-5A] (Mus musculus) PubMed

 23665.

BnIND gene is essential for pod shatter and is highly conserved in Brassica species [IND] (Mus musculus) PubMed

 23666.

This study identified a novel transcriptional regulator, RXE1, controlling xyr1 and cellulase gene expression.[xyr1, RXE1] (Mus musculus) PubMed

 23667.

The mechanism of the reaction of chlorination of tryptophan catalyzed by tryptophan 7-halogenase was studied. (gene: tryptophan 7-halogenase) (Mus musculus) PubMed

 23668.

Gh_D05G0313 and Gh_D05G1124, both contained one significant SNP, highly expressed during ovule and fiber development stages, implying that the two genes may act as the most promising regulators of lint percentage [Gh_D05G0313; Gh_D05G1124] (Mus musculus) PubMed

 23669.

MiR-3470b is a novel host factor regulates bovine ephemeral fever virus replication via directly targeting the MAVS gene in BHK-21 cells.[MiR-3470b] (Mus musculus) PubMed

 23670.

[cd107a] A significant increase in CD107a was observed in all porcine reproductive and respiratory syndrome virus infected groups (Mus musculus) PubMed

 23671.

role in plastoglobule formation and lipid metabolism in chloroplasts, which coordinately regulate the growth and grain filling of the overexpressing lines under heat stress - [FBN1] (Mus musculus) PubMed

 23672.

OsGASR9 transcripts were detected in various tissues, with the lowest and highest levels in leaves and panicles, respectively. Greater mRNA levels accumulated in young, compared with in old, panicles and spikelets. OsGASR9 localized to the plasma membrane, cytoplasm and nucleus.[GASR9] (Mus musculus) PubMed

 23673.

The side chains of Ser28, Gln29, Asp84, and Gln87 of KARI directly interact with nicotinamide and ribose through hydrogen bonds and stabilize the nicotinamide riboside moiety buried in the pocket. [KARI] (Mus musculus) PubMed

 23674.

Further functional assays corroborated the nature of Eap as a DNA binding protein, since Eap suppressed the formation of "neutrophil extracellular traps" (NETs), composed of DNA-histone scaffolds, which are thought to function as a neutrophil-mediated extracellular trapping mechanism.[Eap] (Mus musculus) PubMed

 23675.

Transcriptional analysis revealed that MdWRKY100 was expressed ubiquitously in all examined apple organs. Overexpression in apple increased resistance to Colletotrichum gloeosporioides, while RNAi silencing transgenic plants were more sensitive to Colletotrichum gloeosporioides.[WRKY100] (Mus musculus) PubMed

 23676.

A cotton MYB gene, GhMYB73, was induced by NaCl and abscisic acid (ABA). Silencing GhMYB73 expression in cotton increased sensitivity to salt stress. The cotyledon greening rate of Arabidopsis thaliana over-expressing GhMYB73 under NaCl or mannitol treatment was significantly enhanced during the seedling germination stage.[MYB73] (Mus musculus) PubMed

 23677.

bHLH18 is preferentially expressed during the early fiber elongation stage and negatively regulates fiber elongation and secondary cell wall formation (bHLH18). (Mus musculus) PubMed

 23678.

PRXR1 was verified as a candidate gene that influences cottonseed oil biosynthesis (PRXR1). (Mus musculus) PubMed

 23679.

3, 4-dihydroxyphenylacetaldehyde (DOPAL) synthase plays a critical role in mosquito larval development and adult survival [DOPAL synthase]. (Mus musculus) PubMed

 23680.

Our results suggest that EBV-miR-BART2-5p, which targets the stress-induced immune ligand MICB to escape recognition and elimination by NK cells, may have a role in sustaining high EBV viral loads in CHL paediatric kidney transplant recipients. [miR-BART2] (Mus musculus) PubMed

 23681.

The transcriptional level of the bkd operon was upregulated 5-fold in a pccD gene deletion strain (DeltapccD strain) and decreased 3-fold in a pccD overexpression strain (WT/pIB-pccD), demonstrating that PccD was a negative transcriptional regulator of the operon.[pccD] (Mus musculus) PubMed

 23682.

SMT revealed that about 30% of SftA molecules move through the cytosol, while a fraction of 70% is septum bound and static. In contrast, only 35% of FtsA molecules are static at midcell, while SpoIIIE molecules diffuse within the membrane and show no enrichment at the septum.[ftsa,spoIIIE,sftA] (Mus musculus) PubMed

 23683.

the T. maritima CorA is a Mg(2+) channel and not a Co(2+) channel [CorA] (Mus musculus) PubMed

 23684.

GRMZM2G110929 and GRMZM5G852704 are the potential candidates in the QTL Qsta9.1 for association with maize kernel starch content. [GRMZM2G110929; GRMZM5G852704] (Mus musculus) PubMed

 23685.

Deletion of sll1541 leads to deficiency in retinal synthesis and allows the in vivo reconstitution of far-red-absorbing holo-proteorhodopsin with exogenous retinal analogues, as demonstrated here for all-trans 3,4-dehydroretinal and 3-methylamino-16-nor-1,2,3,4-didehydroretinal.[sll1541] (Mus musculus) PubMed

 23686.

Phg-2 locus was confirmed to be the major locus providing angular leaf spot resistance [Phg-2] (Mus musculus) PubMed

 23687.

These findings demonstrate that MtrA is an important pleiotropic regulator of erythromycin biosynthesis, antibiotic resistance, osmoprotection, and substance transport in Saccharopolyspora erythraea and provide new insights for improving erythromycin production.[MtrA] (Mus musculus) PubMed

 23688.

a C-type ATP-Binding Cassette Transporter that Is Involved in the Root-to-Shoot Translocation of Arsenic - [ABCC7] (Mus musculus) PubMed

 23689.

Mycobacterium tuberculosis Catalase Inhibits the Formation of Mast Cell Extracellular Traps. (Mus musculus) PubMed

 23690.

Cutin induced ancut4 only under oxidative stress conditions.[ancut4 (AN10346)] (Mus musculus) PubMed

 23691.

miR-1225 is significant in multiple malignancies and other pathological reactions; transfection of a miR-1225 mimic or Keap1 silencing inhibits osteoclastogenesis; after miR-1225 inhibition and Keap1 overexpression, TNF was increased; TNFalpha overexpression promoted Keap1 depletion-inhibited BMM osteoclastogenesis; miR-1225 activates Keap1-Nrf2-HO-1 signal to inhibit TNFalpha-induced osteoclastogenesis (MicroRNA-1225). (Mus musculus) PubMed

 23692.

The transmembrane domain of the 2B protein is essential for the apoptotic activity and tetramer formation of the 2B protein [2B protein]. (Mus musculus) PubMed

 23693.

Bacterioruberin not only stabilizes the protein trimeric structure of Archaerhodopsin-4 but also affects the photocycle kinetics and the ATP formation rate. [Archaerhodopsin-4] (Mus musculus) PubMed

 23694.

These results indicated that lnc-13317.1 could inhibit CCNE expression and B16 cell proliferation by targeting complementary binding BRCA1. [lnc13317.1] (Mus musculus) PubMed

 23695.

the CaCLV3_01 gene modulates flowering time and flower number [CaCLV3_01] (Mus musculus) PubMed

 23696.

SRA-HNH containing protein Shp binds to and cuts 5mC DNA, and unmethylated DNA in a Mn(2+) dependent manner, and might be involved in faithful genome inheritance maintenance following DNA damage [Shp (Dr1533)] (Mus musculus) PubMed

 23697.

Despite having the appearance of a BrS enzyme, Gsy has the activity of de novo synthesis of insoluble glucan. Gsy might be an evolutionary intermediate between BrS and GS enzymes.[Gsy] (Mus musculus) PubMed

 23698.

CLIBASIA_01175, renamed, is a periplasmic esterase involved in modification of the lipid A moiety of the lipopolysaccharide.[ LdtP] (Mus musculus) PubMed

 23699.

Recombinant Lactobacillus casei expressing the outer membrane protein W (OmpW) of Aeromonas veronii could elicit protective immunity against A.veronii infections. A 600-bp gene fragment was subcloned into the L.casei expression plasmids pPG-1. (Mus musculus) PubMed

 23700.

SoceCHS1, a type III polyketide synthase (PKS), catalyzed the synthesis of 1,3,6,8-tetrahydroxynaphthalene (T4HN) in vitro T4HN was in turn converted to 1,8-DHN by successive steps of reduction and dehydration, which were catalyzed by BdsA and BdsB.[CHS1,bdsA,bdsB] (Mus musculus) PubMed

 23701.

In this study, the authors report a functional, transferable, plasmid-mediated mcr-1 gene in S. flexneri. They have shown that mcr-1 is located on a novel composite transposon which is flanked by inverted repeats of ISApl1 (Mus musculus) PubMed

 23702.

miRNA-H4-5p could reverse apoptosis induced by actinomycin D and promote cell cycle progression, but miRNA-H4-3p had no such obvious functions [miRNA-H4-5p]. (Mus musculus) PubMed

 23703.

The vsp gene was fine mapped to a 353.7-kb region, and a 201-bp deletion that affected chloroplast development and chlorophyll biosynthesis was found in the candidate gene GhPUR4. [GhPUR4] (Mus musculus) PubMed

 23704.

recombinant OsTHION15 exhibited inhibitory activities toward rice pathogens [OsTHION15] (Mus musculus) PubMed

 23705.

combinations of Rht-B1 and Ppd-D1 alleles control multiple pollinator traits [Rht-B1; Ppd-D1] (Mus musculus) PubMed

 23706.

These data demonstrate that AcrR functions as an important regulator of AcrAB efflux pump and is associated with several phenotypes such as motility, biofilm/pellicle formation and pathogenesis in Acinetobacter nosocomialis.[AcrR, AcrA, AcrB] (Mus musculus) PubMed

 23707.

The authors observed that tenofovir and tenofovir-alafenamide are not substrates of CNT2. Tenofovir-alafenamide influx pathway remains to be clarified.[CNT2] (Mus musculus) PubMed

 23708.

Biochemical characterization of heat-tolerant recombinant L-Arabinose isomerase (araA) from Enterococcus faecium DBFIQ E36 strain has been reported. [araA] (Mus musculus) PubMed

 23709.

the role of the N-terminal region of Delta5 phospholipid desaturases and the individual residues necessary for the activity of this class of enzymes [DesA] (Mus musculus) PubMed

 23710.

microenvironment surrounding FAD mediates its conversion to 8-formyl-FAD in Aspergillus oryzae RIB40 formate oxidase [formate oxidase] (Mus musculus) PubMed

 23711.

Results indicate Porcine epidemic diarrhea virus nsp16 negatively regulates innate immunity to promote viral proliferation [nsp16]. (Mus musculus) PubMed

 23712.

Toxoplasma gondii acetyl-CoA synthetase is involved in fatty acid elongation (of long fatty acid chains) during tachyzoite life stages [ACS] (Mus musculus) PubMed

 23713.

The absence of Ms1 small untranslated RNA results in decreased levels of the mRNAs encoding beta and beta' subunits of RNA polymerase, which is also reflected at the protein level.[Ms1] (Mus musculus) PubMed

 23714.

The large motif contributes to the formation of a substrate-binding surface groove, and is crucial for the selectivity of PBCP toward PSII core proteins. [PBCP] (Mus musculus) PubMed

 23715.

the eIF4E4 N-terminal extension is an intrinsically disordered region that transitions to a partly folded form upon binding to PABP1, whereby this interaction is not modulated by poly(A) binding to PABP1. (Mus musculus) PubMed

 23716.

HE residues 176, 194, and 198 are under positive selection, which may be the result of escape from antibody responses [hemagglutinin-esterase] (Mus musculus) PubMed

 23717.

The data indicate that the uS9 C-terminal tail (its length and the nature of its C-terminal residues) has evolved to control the complex interplay of events surrounding accommodation of initiator and elongator tRNAs at the P- and A-sites of the ribosome (uS9). (Mus musculus) PubMed

 23718.

SpoT requires the ACT domain to efficiently hydrolyze (p)ppGpp. In addition, in vivo and in vitro data show that the phosphorylated version of EIIANtr (EIIANtr approximately P) interacts directly with the ACT and inhibits the hydrolase activity of SpoT (SpoT). (Mus musculus) PubMed

 23719.

a Pol III-Dependent Long ncRNA that Affects Seed Germination and Growth in Arabidopsis - [NR8] (Mus musculus) PubMed

 23720.

The increase in the levels of translation arrest of the studied conservative SecM mutants by the P153A double mutation is due to the increased freedom of movement of the nascent chain within the exit tunnel, which enables the repositioning of key amino acid arrest residues. [secM] (Mus musculus) PubMed

 23721.

The authors show that MrfAB function independent of canonical nucleotide excision repair, forming a novel excision repair pathway. They demonstrate that MrfB is a metal-dependent exonuclease and that the N-terminus of MrfB is required for interaction with MrfA.[MrfAB] (Mus musculus) PubMed

 23722.

A mechanism by which T7 RNA polymerase transcripts stimulate the innate immune system.[T7 RNA polymerase] (Mus musculus) PubMed

 23723.

TbMCM-BP, a replication initiation protein, also guides the initiation, termination and directionality of transcription (TbMCM-BP). (Mus musculus) PubMed

 23724.

In the absence of YocM the survival of salt shocked cells is impaired, and increased levels of YocM protect Bacillus subtilis exposed to heat or salt.[YocM] (Mus musculus) PubMed

 23725.

The Dictyostelium Erk2 MAPK is required for chemotactic movement to both folate and cAMP suggesting Erk2 plays a critical role in the general cellular response to chemoattractants. [Erk2] (Mus musculus) PubMed

 23726.

results suggested that miR-218 and miR-618 play an important role in osteoclastogenesis via TLR-4/MyD88/NF-kappaB signaling pathway[miR-618] (Mus musculus) PubMed

 23727.

The Anabaena Sensory Rhodopsin pH-dependent spectrum is the consequence of the competitive stabilization of retinal ground and excited states by the protein electrostatic potential. [Anabaena Sensory Rhodopsin] (Mus musculus) PubMed

 23728.

myogenic regulatory factor 4 and its muscle-specific promoter activity [MRF4] (Mus musculus) PubMed

 23729.

Capsicum annuum DHN5 (a dehydrin gene from pepper) -overexpressing plants exhibited enhanced tolerance to salt and osmotic stresses as compared to the wild type and also showed increased expression of salt and osmotic stress-related genes. [DHN5] (Mus musculus) PubMed

 23730.

electrostatic analysis of the cytoplasmic domain of the KcsA potassium channel [KcsA] (Mus musculus) PubMed

 23731.

Leishmanial AK2a can prevent ATP mediated cytolysis of macrophage cells and thereby probably play a role in preserving integrity of host cells for survival of [adenylate kinase 2a]. (Mus musculus) PubMed

 23732.

Domains two and three of Escherichia coli ribosomal S1 protein confers 30S subunits a high affinity for downstream A/U-rich mRNAs [ribosomal S1 protein] (Mus musculus) PubMed

 23733.

results suggest that an N-terminal extension allows PlzD to localize at the cell pole but causes aggregation and leads to inhibition of motility; in V. alginolyticus, PlzD has a potential property to associate with the polar flagellar motor but this interaction is too weak to inhibit rotation [plzD] (Mus musculus) PubMed

 23734.

The cloned DNA fragment containing the gene erm(49), encoding a rRNA Methylase, confers resistance to erythromycin and clindamycin in B. breve. [erm49] (Mus musculus) PubMed

 23735.

Study found evidence for very different phosphorylation patterns resulting in p58, the hyperphosphorylated form of NS5A protein. These results challenge the concept of p58 being a homogenous species of NS5A molecules phosphorylated at the same positions and argues for at least two independently phosphorylated variants showing the same electrophoretic mobility, likely serving different functions. [NS5A] (Mus musculus) PubMed

 23736.

Results show that CVB3 2A protein promoted the transcriptional activities of SREBP1a, which are mediated by the SP1 transcription factor. Also, MEK/ERK signaling pathway is critical for 2A-induced SREBP1a activation and lipid accumulation. [NS2A] (Mus musculus) PubMed

 23737.

Deletion of two or more of aro8, aro9 and aro10 genes increased growth lag phase, with the greatest delay exhibited by F15 Deltaaro8 Deltaaro9. The single Deltaaro8 deletion decreased methionol by 44% in BY4743 and 92% in strain F15, while the Deltaaro9 deletion increased methionol by 46% in strain F15 but not in strain BY4743. Single deletion of Deltaaro10 had no effect on methionol.[aro8, aro9, aro10] (Mus musculus) PubMed

 23738.

Enzymatic properties from Acylpeptidyl-oligopeptidase (AOP) from Porphyromonas gingivalis was characterized. AOP should be settled into one exopeptidase family that predominantly liberates acyl-dipeptides with hydrophobic P1- and P2- position residues. (gene: Acylpeptidyl-oligopeptidase) (Mus musculus) PubMed

 23739.

Saccharomyces cerevisiae strain overexpressing Ppn2 was constructed and Ppn2 enzymatic properties (including substrate specificity) were compared with those of Ppn2, Ppx1, Ppn1, and Ddp1. (gene: Ppn2) (Mus musculus) PubMed

 23740.

genetic locus and role to increase in coleoptile length and establishment - [Locl-A1] (Mus musculus) PubMed

 23741.

This indicated that Eap contributes to the rough irregular surface structure of the MR23 biofilm and that both Eap and SasG play roles in biofilm thickness.[Eap,SasG] (Mus musculus) PubMed

 23742.

Hcp (PG0893), a putative nitric oxide reductase, is the only gene significantly upregulated in response to nitrite and that this regulation is dependent on HcpR.[Hcp] (Mus musculus) PubMed

 23743.

Mp1p-ligand-binding domain 1 and 2 bind arachidonic acid.[Mp1] (Mus musculus) PubMed

 23744.

The authors have identified an outer membrane protein of Sinorhizobium meliloti, called NsrA, that transduces Medicago plant signals to adenylate cyclases in the inner membrane, thereby triggering a cAMP signaling cascade that controls infection. [NsrA] (Mus musculus) PubMed

 23745.

Crystal structures of the amino-terminal domain of LpoA from Escherichia coli and Haemophilus influenzae have been resolved.[LpoA] (Mus musculus) PubMed

 23746.

Crystal structure of the cold-adapted haloalkane dehalogenase DpcA from Psychrobacter cryohalolentis K5 has been presented. (Mus musculus) PubMed

 23747.

Rab-interacting lysosomal protein (LvRILP) contained a conserved RILP region from 277 amino acid to 325 amino acid. Both the LvRILP and Rab7 mRNA were most highly expressed in stomach and most lowly expressed in hemocyte, which were significantly up-regulated and exhibited similar kinetics post WSSV infection (Rab-interacting lysosomal protein). (Mus musculus) PubMed

 23748.

Taken together, these results suggest that enterohemorrhagic Escherichia coli Tir negatively regulates proinflammatory responses by inhibiting the activation of TAK1, which is essential for immune evasion.[Tir] (Mus musculus) PubMed

 23749.

A single-nucleotide change in ZmDMP leads to a 2-3-fold increase in the haploid induction rate (ZMDMP) (Mus musculus) PubMed

 23750.

CYP443C1 (CYP74 clan) Cytochrome of Sea Anemone Nematostella vectensis-the First Metazoan Enzyme Possessing Hydroperoxide Lyase/Epoxyalcohol Synthase Activity [CYP443c1] (Mus musculus) PubMed

 23751.

characterization and role in flower organ development - [miR172] (Mus musculus) PubMed

 23752.

We detected the HpSpo0J-HpSoj-DNA complex by electron microscopy and show that this nucleoid-adaptor complex (NAC) is formed through HpSoj and HpSpo0J interaction and parS DNA binding. NAC formation is promoted by HpSoj participation and specific parS DNA facilitation. (Mus musculus) PubMed

 23753.

The authors demonstrated that XopL of Xanthomonas campestris Xcc8004 is a virulence factor and interferes with innate immunity of Arabidopsis by suppressing pathogen-associated molecular pattern-triggered immunity (PTI) signaling, independent of mitogen-activated protein kinases.[XopL] (Mus musculus) PubMed

 23754.

GlnA, a glutamine synthetase essential for ammonia assimilation and glutamine biosynthesis from glutamate, was found to be regulated negatively by EsrB. [EsrB, GlnA] (Mus musculus) PubMed

 23755.

LcGCSFb may be involved in antibacterial immunity via promoting the inflammatory response and the phagocytic activity of leukocytes. To the authors' knowledge, this is the first report on immunoregulatory roles of GCSF in teleost.[GCSFb] (Mus musculus) PubMed

 23756.

these results suggest that ZmASR3 acts as a positive regulator of drought tolerance in plants. (Mus musculus) PubMed

 23757.

Pseudomonas protegens Pf-5 YerE was crystallized and its structure was determined to a resolution of 1.55 A. [YerE] (Mus musculus) PubMed

 23758.

Positional cloning revealed that DYE1 encodes Lhca4, a subunit of the light-harvesting complex I (LHCI). In dye1-1, amino acid substitution occurs at the location of a highly conserved amino acid residue involved in pigment binding; indeed, a severely impaired structure of the PSI-LHCI super-complex in dye1-1 was observed in a blue native PAGE analysis. [DYE1,Lhca4] (Mus musculus) PubMed

 23759.

Results collectively suggest that CgAATase was a potential marker of oyster granulocytes, and the granulocytes could be effectively isolated from total circulating hemocytes by immunomagnetic bead coated with the anti-CgAATase monoclonal antibody. (Mus musculus) PubMed

 23760.

The lysine 299 residue of Mrp1 played its essential roles in conferring salt and alkaline tolerance. [ Mrp1 ] (Mus musculus) PubMed

 23761.

MAL62 and TPS1 overexpression in the NTH1 deletion background further strengthened freezing tolerance and improved leavening ability.[MAL62] (Mus musculus) PubMed

 23762.

CsMAPEG can actively respond to propamocarb stress and effectively reduce the propamacarb residue abundance in cucumber fruits (CsMAPEG) (Mus musculus) PubMed

 23763.

CpHDA3 protein could physically interact with CpERF9 and enhance the transcriptional repression activities of CpERF9 to downstream genes CpPME1, CpPME2 and CpPG5.[ERF9,HDA3,PME1,PME2,PG5] (Mus musculus) PubMed

 23764.

BpsR, a negative regulator of biofilm formation and Bps polysaccharide production, controls the growth of Bordetella bronchiseptica by repressing the expression of nic genes.[BpsR] (Mus musculus) PubMed

 23765.

Two negatively charged residues (E153 and D160) of Art(MP)2 are crucial for binding of positively charged amino acids.[ Art(MP)2] (Mus musculus) PubMed

 23766.

results of in vitro translation experiment suggest involvement of the N-terminal domain of eL24 in the translation initiation. Therefore, eL24 performs number of tasks required for the optimal ribosome functionality (Mus musculus) PubMed

 23767.

It is proposed that decreased 19S proteasome subcomplex activity leads to the stabilisation of Rpn4p, a transcription factor and proteasome substrate. In turn, stabilised Rpn4p may upregulate stress-responsive genes that participate in the response to 4-nitroquinoline-1-oxide-induced oxidative stress. (Mus musculus) PubMed

 23768.

PCNA enhanced the nucleotide incorporation rate by >10 fold. Compared to wild-type, a growth-defective yeast PCNA mutant (DD41,42AA) showed substantially less stimulation of the Pol delta nucleotide incorporation rate, identifying the face of PCNA that is important for the acceleration of catalysis. (Mus musculus) PubMed

 23769.

In this study, the authors showed that LoiA directly represses the expression of the lon gene during invasion by binding to the promoter region of lon. The activation of Salmonella typhimurium SPI-1 gene expression by LoiA is associated with its repression of lon.[LoiA, lon] (Mus musculus) PubMed

 23770.

Taken together, these data suggest that Rex plays critical roles in the virulence and oxidative stress response of Streptococcus suis serotype 2.[Rex] (Mus musculus) PubMed

 23771.

By activating CsrB RNA expression, the Yersinia pseudotuberculosis BarA/UvrY two-component system has pleiotropic effects that impact biofilm production and stability.[CsrB, BarA, UvrY] (Mus musculus) PubMed

 23772.

Taken together, these data suggest that in these conditions, CpxRA activates gene expression in a largely NlpE- and CpxP-independent manner. Compared to wildtype, 161 genes were downregulated in the DeltacpxRA strain, while being upregulated or unchanged in the Cpx auxiliary protein deletion strains.[CpxRA] (Mus musculus) PubMed

 23773.

these findings highlight an important role for miR-133b/MMP-9 axis in atherosclerosis. (Mus musculus) PubMed

 23774.

Enterococcus faecalis relies on both a TCS (CroS/R) and an eSTK (IreK) for intrinsic resistance to cell wall-targeting antibiotics.[CroS, CroR, IreK] (Mus musculus) PubMed

 23775.

YbeY endoribonuclease are required for cellular morphology, efficient control of mRNA levels, and virulence. [YbeY] (Mus musculus) PubMed

 23776.

Elongation factor Tu (EF-Tu) is a three-domain protein that is responsible for delivering aminoacyl-tRNA (aa-tRNA) molecules to the ribosome. This study highlights the dynamic nature of EF-Tu by revealing a relationship between conformational disorder and biological function. [EF-Tu] (Mus musculus) PubMed

 23777.

A c-di-AMP effector protein, CabP, affects c-di-AMP homeostasis. [CabP] (Mus musculus) PubMed

 23778.

VacA degradation is independent of autophagy and proteasome activity but dependent on lysosomal acidification. [VacA] (Mus musculus) PubMed

 23779.

Survival of mice infected with the cssA deletion mutant is significantly increased.[cssA] (Mus musculus) PubMed

 23780.

Maximal cyclic electron flow rate is independent of PGRL1 in Chlamydomonas. (Mus musculus) PubMed

 23781.

a novel role for the N-terminus of Sgo1 in CENP-A(Cse4) mediated recruitment of Sgo1 to centromeric chromatin for faithful chromosome segregation, is reported.[CENP-A, Sgo1] (Mus musculus) PubMed

 23782.

The Pid4 protein is localized in both the nucleus and cytoplasm. Introduction of Pid4 into susceptible rice cultivars confers race-specific resistance to leaf and neck blast. [Pid4] (Mus musculus) PubMed

 23783.

Loss of OmpK35 or OmpK36 porin is paired with reductions in capsule, increased LPS content, and up-regulated transcription of compensatory porin genes in clinical isolates of Klebsiella pneumoniae. Loss of both porins results in significant increase in capsule production. Loss of OmpK35 alone or dual porin loss is associated with reduced oxidative burst by macrophages and increased bacteria survival of phagocytic killing. (Mus musculus) PubMed

 23784.

In the final step of biotin biosynthesis, a radical S-adenosyl-l-methionine enzyme, biotin synthase (BioB), converts the substrate dethiobiotin to biotin through the stepwise formation of two C-S bonds. This electron paramagnetic resonance work has derived a structural model of a paramagnetic intermediate generated after the first hydrogen-atom abstraction in the biotin synthase. [BioB] (Mus musculus) PubMed

 23785.

The adhesion and invasion capacities of the mutant strain RA2281 (designated Yb2DeltagldM) in Vero cells and the bacterial loads in the blood of infected ducks were significantly reduced. RNA-Seq and PCR analyses showed that six genes were upregulated and five genes were downregulated in the mutant strain Yb2DeltagldM and that these genes were mainly involved in the secretion of proteins.[ GldM] (Mus musculus) PubMed

 23786.

The murine norovirus NS3 has an Mg(2+)-dependent NTPase activity, and site-directed mutagenesis of the conserved NTPase motifs blocked enzyme activity and viral replication in cells.[NS3] (Mus musculus) PubMed

 23787.

In model of vascular injury long noncoding RNA-steroid receptor RNA activator ( lncRNA-SRA) promoted vascular smooth muscle cell proliferation by activating the MEK-ERK-CREB pathway. (Mus musculus) PubMed

 23788.

Together, the present results suggested that HaVri was involved in larval moulting and metamorphosis and was regulated by 20E and JHA in H. armigera.[Vri] (Mus musculus) PubMed

 23789.

These results suggest that Entamoeba histolytica calcium/cation exchanger (CCX) plays important roles in the programmed cell death and in the in vitro virulence of Entamoeba histolytica.[CCX] (Mus musculus) PubMed

 23790.

A candidate tRNA isopentenyltransferase (IPT) gene with three alternative splicing isoforms (BmIPT1-BmIPT3) was identified in Bombyx mori (silkworm); only BmIPT1 could complement a yeast mutant lacking tRNA IPT. (Mus musculus) PubMed

 23791.

Collectively, the authors' molecular and physiological data on medfly CcapOBP22 suggest its involvement in intersex olfactory communication.[OBP22] (Mus musculus) PubMed

 23792.

The function of hetC is influenced by the genomic background and epistasis and constitutes an example of evolution under way.[hetC] (Mus musculus) PubMed

 23793.

DdrI is crucial for the completion of cell division, chromosome segregation and stress conditions.[DdrI] (Mus musculus) PubMed

 23794.

PthXo3 suppresses the plant's innate immunity by inhibiting hypersensitive response (HR) and callose deposition.[PthXo3] (Mus musculus) PubMed

 23795.

DasR controls acetate assimilation by directly repressing the transcription of the acsA1 gene. [DasR, acsA1] (Mus musculus) PubMed

 23796.

yeast Mrc1 is able to enhance the activity of DNA polymerase (Pol ), the major leading strand replicase.[Mrc1, Dna polymerase epsilon] (Mus musculus) PubMed

 23797.

FupA/B deletion promoted increased secretion of outer membrane vesicles. [FupA] (Mus musculus) PubMed

 23798.

the Lmb can exist in different conformational states with subtle differences in the overall fold based on the presence or absence of the metal.[Lmb] (Mus musculus) PubMed

 23799.

This finding confirmed that miR-511 inhibits proliferation and promotes apoptosis by downregulating the IGF-1 in PK-15 cells. (Mus musculus) PubMed

 23800.

Dimer-of-Trimers Assembly Prevents Catalysis at the Transferase Site of Prokaryotic FAD Synthase [FAD synthase] (Mus musculus) PubMed

 23801.

Data suggest that VP1-145Glycine virus is adsorbed by attachment receptors such as heparan sulfate (HS) during circulation in vivo, leading to abortive infection of HS-positive cells. This trapping effect is thought to be a major mechanism of attenuation of the VP1-145G virus. [VP1] (Mus musculus) PubMed

 23802.

The conserved cage formed by the aromatic amino acids in TbTFIIS2-2 PWWP domain is essential for its binding to methylated histones. (Mus musculus) PubMed

 23803.

Both PlAzg1 and PlAzg2 display high affinity for adenine with Km of 2.95 +/- 0.22 and 1.92 +/- 0.22 muM. [PlAzg1 and PlAzg2] (Mus musculus) PubMed

 23804.

(FnEDA) FnEDA deletion results in significantly reduced chronic fibrotic scarring and enhanced functional recovery. (Mus musculus) PubMed

 23805.

Highly conserved nucleotide motifs present in the 5'UTR of the heme-receptor gene shmR are required for HmuP-dependent expression of shmR in Ensifer meliloti (Mus musculus) PubMed

 23806.

Structure and nucleotide-induced conformational dynamics of the Chlorobium tepidum Roco protein. (Mus musculus) PubMed

 23807.

The horizontal transfer of the BmDODA1 gene in the silkworm may be involved in dopa metabolism and contribute to antimicrobial activity in Bombyx mori (DODA1). (Mus musculus) PubMed

 23808.

The architecture of yellow cis-regulatory sequences (from D. melanogaster, D. pseudoobscura, and D. willistoni) is less modular and more variable among species than previously described, with the observed organization of enhancer activities potentially making yellow expression more robust, as well as more amenable to evolutionary change. (gene: yellow) (Mus musculus) PubMed

 23809.

The architecture of yellow cis-regulatory sequences (from D. melanogaster, D. pseudoobscura, and D. willistoni) is less modular and more variable among species than previously described, with the observed organization of enhancer activities potentially making yellow expression more robust, as well as more amenable to evolutionary change. (gene: yellow) (Mus musculus) PubMed

 23810.

RpoS coordinates the expression of both the AlgE1-7 epimerases and the EexDEF protein complex responsible for their transport (Mus musculus) PubMed

 23811.

Taken together, these data suggest that Fur and OmpR control iron/heme acquisition via a complex mechanism based on negative regulation of hemR1 and hemR2 at the transcriptional level.[OmpR, hemR1, hemR2] (Mus musculus) PubMed

 23812.

Moreover, using a transient agro-infiltration patch assay and a Turnip crinkle virus (TCV) movement complementation assay, it was demonstrated that p15 possesses weak RNA silencing suppressor activity. [p15] (Mus musculus) PubMed

 23813.

[Fe]-hydrogenase (Hmd) catalyzes the reversible hydrogenation of methenyltetrahydromethanopterin (methenyl-H4 MPT(+) ) with H2. Hmd from Methanothermobacter marburgensis (mHmd) was found in a hexameric state, where an expanded oligomerization loop is detached from the dimer core and intrudes into the active site of a neighboring dimer. [mHmd] (Mus musculus) PubMed

 23814.

These findings support the development of small animal models of S. aureus infection with the potential for demonstrating the importance of LukGH in pathogenesis. (Mus musculus) PubMed

 23815.

knockdown of ENSMUST00000134285 inhibited MAPK11 activity and increased the myocardial apoptotic ratio; overexpression increased MAPK11 activity and decreased the myocardial apoptotic ratio; lncRNA ENSMUST00000134285 is an important regulatory molecule in aging-mediated effects upon apoptosis [lncRNA ENSMUST00000134285 ] (Mus musculus) PubMed

 23816.

these structural and biophysical findings provide insights into the molecular mechanism of membrane targeting by TgPLP1.{TgPLP1] (Mus musculus) PubMed

 23817.

Overall, thes results indicated that EhADH disturbed tight junctions from the extracellular space and also intracellularly, suggesting that EhADH affects by itself tight junction proteins, and possibly synergizes the action of other parasite molecules during epithelial invasion.[ADH] (Mus musculus) PubMed

 23818.

Type 1 and type 2 isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IDI-1 and IDI-2) catalyze the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). IDI-1 and IDI-2 catalyze concerted asynchronous double bond isomerizations, which reduce the possibility of substrate inactivation by alkylation of their active-site residues. [IDI-1] (Mus musculus) PubMed

 23819.

rfk-1 is required for spore killing and that it is located next to the right border of Sk-2. This location allows it to escape silencing caused by a genome defense process called meiotic silencing by unpaired DNA (MSUD). rfk-1 gene has 4 exons, 3 introns. Stop codon at "position 103" in rfk-1 transcript undergoes RNA editing during sexual development. The edited rfk-1 transcript contains the code for a 130-aa protein. (Mus musculus) PubMed

 23820.

Type 1 and type 2 isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IDI-1 and IDI-2) catalyze the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). IDI-1 and IDI-2 catalyze concerted asynchronous double bond isomerizations, which reduce the possibility of substrate inactivation by alkylation of their active-site residues. [IDI-2] (Mus musculus) PubMed

 23821.

Study reports cloning of a cDNA sequence encoding one galectin in scleractinian coral Pocillopora damicornis (PdGLT-1). The deduced PdGLT-1 protein was composed of one signal peptide, one Collagen domain and one Gal-Lectin domain. PdGLT-1 recombinant protein (rPdGLT-1) was expressed and purified in vitro. Binding activities of rPdGLT-1 to bacteria and symbiont were determined using western blotting method. [PdGLT-1] (Mus musculus) PubMed

 23822.

The MinD and MinE protein system was encapsulated in giant unilamellar vesicles (GUVs). Using confocal fluorescence microscopy, the study identified several distinct modes of spatiotemporal patterns inside spherical GUVs. It demonstrated how reaction-diffusion-based protein self-organization can directly yield visible mechanical effects on membrane compartments, even up to autonomous division. [MinD, MinE] (Mus musculus) PubMed

 23823.

Constitutive expression of BdRSL2, but not expression of BdRSL3, consistently improved Phosphorus nutrition.[BdRSL3, BdRSL2] (Mus musculus) PubMed

 23824.

This is the first report of a linear peptide-like molecule that interferes with agr activation by competitive binding to AgrC (Mus musculus) PubMed

 23825.

Under denitrifying conditions, the nirK (copper-containing nitrite reductase) and nirS (cytochrome cd1 nitrite reductase) single gene deletion mutants grow normally and their nitrite reductases (NiR) activity is not affected. The nirKS double deletion mutant grows more slowly, presumably because the impaired NiR activity results in nitrite accumulation. (Mus musculus) PubMed

 23826.

SSL5 binds to C1Inh in a sialic acid-dependent fashion and modulates the host immune defense.[SSL5] (Mus musculus) PubMed

 23827.

cryo-electron microscopy structures of the amphioxus ProtoRAG transposase (an evolutionary relative of RAG); findings reveal a two-tiered mechanism for the suppression of RAG-mediated transposition, illuminate the evolution of V(D)J recombination and provide insight into the principles that govern the molecular domestication of transposons (Mus musculus) PubMed

 23828.

identification of a fourth promoter of the sigS operon, termed P4, located in a unique position internal to the sigS coding region [sigS] (Mus musculus) PubMed

 23829.

increases in expression of HSP90 are responsible for the enhanced resistance against the aphid under elevated carbon dioxide. [HSP90, R] (Mus musculus) PubMed

 23830.

Overexpression of uc.457 suppressed the mRNA and protein expression of histone cell cycle regulation defective homolog A, natriuretic peptide A, cardiac muscle troponin T and myocytespecific enhancer factor 2C. (UC.457 long noncoding RNA) (Mus musculus) PubMed

 23831.

Here, the authors identified two contact-dependent growth inhibition (CDI) systems, an intact cdiBAI operon with a truncated CdiB due to an unexpected mutation and an 'orphan' cdiA-CT/cdiI module in the probiotic Escherichia coli Nissle 1917 (EcN) genome.[CdiB, VdiA, CdiI] (Mus musculus) PubMed

 23832.

Leaf initiation rate was unaffected by Ppd-1a alleles so the final leaf number (FLN) was reduced in parallel with reductions in the duration of the vegetative phase. Spikelet primordia initiation was accelerated and consequently the effect on spikelets per spike was less than proportional to the effect on the duration of spikelet initiation.[Ppd-1] (Mus musculus) PubMed

 23833.

Methionine gamma-lyase (PG0343) of Porphyromonas gingivalis W83 catalyses hydrogen sulfide (H2S) production from l-cysteine and produces methyl mercaptan (CH3SH) from l-methionine in a mouse abscess model. Abscess formation by P. gingivalis, but not PG0343 deletion mutant, differ in the presence and absence of l-cysteine. The presence of l-methionine does not affect the size of abscesses caused by the wild type and mutant (Mus musculus) PubMed

 23834.

Deletion of PBP1a/LpoA caused aberrant cell morphology, enhanced sensitivity to various envelope stresses and outer membrane permeability. [LpoA] (Mus musculus) PubMed

 23835.

Taken together, this study identified the first member of the XRE family of transcriptional regulators, SrtR, that is involved in stress tolerance and virulence.[SrtR] (Mus musculus) PubMed

 23836.

Three non-functional variants were detected in the coding sequence of TaPpm1 from non-purple seed lines, in which the function of TaPpm1 was destroyed either by insertion-induced frame shifts or truncated peptides. There were six 261-bp tandem repeats in the promoter region of TaPpb1 in the purple-grained varieties, while there was only one repeat unit present in the non-purple varieties.[Ppm1,Ppb1] (Mus musculus) PubMed

 23837.

Alterations of cysteine protease (CP) activity in response to cyclooxygenase (Cox) Cox gene silencing may be a negative feedback mechanism in Entamoeba histolytica to limit proteolytic activity during colonization that can inadvertently trigger inflammation in the gut.[CP, Cox] (Mus musculus) PubMed

 23838.

The authors used the tetracycline inducible system to drive expression of hemagglutinin epitope tagged GRA16 and GRA24 after inducing stage conversion and show that these proteins are not secreted beyond the cyst wall membrane. This suggests that secretion of GRA beyond the parasitophorous vacuole membrane is not important for the tissue cyst stage of Toxoplasma.[GRA16, GRA24] (Mus musculus) PubMed

 23839.

these findings give us novel insights into comprehensive understanding of GhFSN1 function in fiber development.[FSN1] (Mus musculus) PubMed

 23840.

iron-stress activated RNA 1 (IsaR1) expression is highly dynamic in response to fluctuations in external iron supply and salinity enabling the possibility of posttranscriptional regulation of the salt-induced ggpS gene by IsaR1 (IsaR1). (Mus musculus) PubMed

 23841.

CsbHLH18 plays a positive role in cold tolerance through, at least partly, modulation of ROS homeostasis by directly regulating the antioxidant gene.[HLH18] (Mus musculus) PubMed

 23842.

Data indicate that pM91 of murine cytomegalovirus is a component of the viral late gene transcription factor complex and that the pM91-pM79 interaction is essential for viral late gene expression. Also, residues E61, D62, D89, and D96 in pM91 were found to be essential for the pM91-pM79 interaction. [pM91 & pM79] (Mus musculus) PubMed

 23843.

The authors concluded that the modulation of biofilm- and virulence-related genes by BfvR led to increased biofilm formation and reduced virulence of Yersinia pestis biovar Microtus.[BfvR] (Mus musculus) PubMed

 23844.

Expression of drp was found to depend on the master regulator DnrT, whereas the absence of DrpA or DrpB increased the expression of both DnrS and DnrT. [DrpA, DrpB] (Mus musculus) PubMed

 23845.

sorbitol plays an essential role in stamen development and pollen tube growth via MdMYB39L in apple.[MdMYB39L] (Mus musculus) PubMed

 23846.

AFLA_051390 encodes a copper-transporting ATPase involved in biosynthesis of conidial pigment [AFLA_051390] (Mus musculus) PubMed

 23847.

Loss of PePacC resulted in an obvious decrease in growth and conidiation of P. expansum cultured in both acidic and alkaline conditions. [pacC] (Mus musculus) PubMed

 23848.

The role of RAD23 in virulence is due to its function in proteasomal-mediated protein degradation rather than nucleotide excision repair.[RAD23] (Mus musculus) PubMed

 23849.

Fbx23 F-box protein is identified as being involved in CreA-mediated catabolite repression and the fbx23 deletion mutants exihibt impaired xylanase production under repressing (glucose) and derepressing (xylan) conditions. Upon the addition of glucose, CreA dissociates from the ubiquitin SCF (Skp-Cullin-F-box) ligase complex and is transported into the nucleus. (Mus musculus) PubMed

 23850.

Study reports the functional characterization of zebrafish CD44c, which is more similar to CD44b antigen isoforms rather than CD44a based on amino acid composition and phylogenetic analysis. The expression of zebrafish CD44c was inducible in response to bacterial and viral infections. During Spring viraemia of carp virus infection CD44c overexpression led to the increased virus loads and decreased survival rate. [CD44c] (Mus musculus) PubMed

 23851.

This study exposes the significance of lysX in the metabolism and virulence of the environmental pathogen Mycobacterium avium hominissuis.[lysX] (Mus musculus) PubMed

 23852.

missense mutations of K. pneumoniae crrB lead to increased expression of H239_3064, leading in turn to decreased susceptibility to colistin, tetracycline and tigecycline [CrrB] (Mus musculus) PubMed

 23853.

Using a murine model, comparing the USA300 and USA300DeltasaeR/S strains, the authors demonstrate that Staphylococcus aureus pathogenesis following influenza A virus infection is SaeR/S dependent.[SaeR, SaeS] (Mus musculus) PubMed

 23854.

Usf2 transactivates S. aurata glud by binding to an E-box located in the proximal region of glud promoter.[Usf2] (Mus musculus) PubMed

 23855.

Results indicate that MrArk1(Actin-regulating kinase) is involved in the heat tolerance, sporulation, and virulence of M. robertsii, and thus is an important factor for sustaining the fungal potential against insect pests [Ark1]. (Mus musculus) PubMed

 23856.

we demonstrate that Atrolnc-1 interacts with ABIN-1, promoting the activation of NF-kappaB and resulting in the increase of MuRF-1 transcriptional output in muscle. (Mus musculus) PubMed

 23857.

Results indicate that the association of VP3 with endosomes has a relevant role in the IBDV replication cycle. [VP3] (Mus musculus) PubMed

 23858.

functional domains of FK506-binding protein 35 from Plasmodium knowlesi [FKBP35] (Mus musculus) PubMed

 23859.

Study identified identified an mRNA binding protein (named virus response 1, vr1) which is involved in symptom expression. Downregulation of vr1 in the virus-infected fungus and vr1 deletion evoke virus infection-like symptoms, while constitutive expression overrules the cytopathic effects of the virus infection. [vr1] (Mus musculus) PubMed

 23860.

SsCP1 interacts with PR1 in the apoplast to facilitate infection by S. sclerotiorum.[SsCP1] (Mus musculus) PubMed

 23861.

pathway leading to a cation-binding pocket determines the selectivity of the NhaP2 antiporter in Vibrio cholera [NhaP2] (Mus musculus) PubMed

 23862.

These results identify PITA and PISA as selective regulators of p53-mediated glycolysis and mitochondrial respiration.[PITA, PISA] (Mus musculus) PubMed

 23863.

RMP1 protein could be involved in the process of OXA1-dependent protein insertion. (RMP1 AND oxa1 proteins) (Mus musculus) PubMed

 23864.

detailed structural study of solvent accessibility of the HET-s(218-295) prion protein [Het-s] (Mus musculus) PubMed

 23865.

Results show that IDC1 seems to play a key role in sexual reproduction [IDC1] (Mus musculus) PubMed

 23866.

data presented in this paper show that segment 29 corresponds to a gene encoding a polyketide synthase, designated PaPKS1, and identifies two mutations that completely or partially abolish the activity of the PaPKS1 polypeptide[PaPKS1] (Mus musculus) PubMed

 23867.

Hsp104-dependency appears less stringent in P. anserina than in yeast; presumably because in Podospora prion propagation occurs in a syncitium[Hsp104 and Het-s] (Mus musculus) PubMed

 23868.

PaTrx1 and PaTrx3 are two cytosolic thioredoxins of the filamentous ascomycete Podospora anserina involved in sexual development and cell degeneration [Trx1, Trx3] (Mus musculus) PubMed

 23869.

NMR study of HET-s(218-289) fibrils shows it forms a left-handed beta solenoid, with each molecule forming two helical windings, a compact hydrophobic core, at least 23 hydrogen bonds, 3 salt bridges & 2 asparagine ladders [HET-s] (Mus musculus) PubMed

 23870.

PaPls1 plays a crucial role in germination of ascospores. [Pls1] (Mus musculus) PubMed

 23871.

PaNAT1 and PaNAT2 are acetyltransferases conferring tolerance to toxic aromatic amine chemicals [PaNAT1, PaNAT2] (Mus musculus) PubMed

 23872.

Data show that the three adPEO-associated mutations introduced into the Podospora anserina ANT1 ortholog dominantly cause severe growth defects, decreased ROS, and accumulation of large-scale mtDNA deletions leading to premature death: [ANT1] (Mus musculus) PubMed

 23873.

PaNox1 and PaNox2 regulate cellulose degradation, and are required for the development of cellular structures dedicated to the penetration of cellulose. [Nox1; Nox2] (Mus musculus) PubMed

 23874.

Deletion of PaMth1 was found to lead to a decreased resistance against exogenous oxidative stress and to a shortened lifespan suggesting a role of PaMTH1 as a longevity assurance factor in a new molecular pathway involved in lifespan control [PaMTH1] (Mus musculus) PubMed

 23875.

HET-S fails to form fibrils in vitro and that it inhibits HET-s PFD fibrillization in trans. [HET-S] (Mus musculus) PubMed

 23876.

Toxic and nontoxic HET-s amyloids differ not only in their structures but also in their assembling process.[HET-s] (Mus musculus) PubMed

 23877.

The exchangeable side-chain protons inside the hydrophobic core of HET-s(218-289) do not exchange over time intervals of weeks-to-months. (Mus musculus) PubMed

 23878.

FgHET-s(218-289) leads to higher spontaneous prion formation rates and mitotic prion stability than HET-s(218-289). [HET-s] (Mus musculus) PubMed

 23879.

HET-s(218-289) adopts a beta-solenoidal structure at neutral pH, and shown that at low pH, it forms either a beta-solenoid or a stacked beta-sheet structure, depending on the integrity of the protein and the conditions of fibrillization.[HET-s] (Mus musculus) PubMed

 23880.

structure and function of Lon protease [Lon1] (Mus musculus) PubMed

 23881.

The product of Pa_3_10940 is the first report of an enzyme that displays bifunctional exo-beta-(1,3)/(1,6) and endo-beta-(1,4) activities toward beta-glucans and therefore cannot readily be assigned to existing Enzyme Commission groups.[Pa_3_10940] (Mus musculus) PubMed

 23882.

The mechanism of a non-toxic HET-s prion conversion of a soluble HET-S protein into an integral membrane protein that destabilizes membranes.[HET-S] (Mus musculus) PubMed

 23883.

Poly(ADP-ribose) polymerase is a substrate recognized by two metacaspases of Podospora anserina. [PaParp] (Mus musculus) PubMed

 23884.

Data indicate that the HET-s(218-289) fibrils formed under acidic conditions have a stacked beta-sheet architecture commonly found in short amyloidogenic peptides and denatured protein aggregates: [HET-s] (Mus musculus) PubMed

 23885.

The first crystal structures of two fungal GH62 alpha-L-arabinofuranosidases from the basidiomycete Ustilago maydis (UmAbf62A) and ascomycete Podospora anserina (PaAbf62A), are reported.[PaAbf62A] (Mus musculus) PubMed

 23886.

Data suggest activity/structure of HET-S are very robust; only a few key mutations are able to corrupt structure/function; some mutations strongly destabilize folding, many increase stability of folding. [vegetative incompatibility protein BIG S] (Mus musculus) PubMed

 23887.

study identified the fungal p22(phox) homologue as being mutated in the Podospora anserina mutant IDC(509; Functional studies show that the fungal p22(phox), PaNoxD, acts along PaNox1, but not PaNox2 [NoxD] (Mus musculus) PubMed

 23888.

Artificial NWD2 variants induce formation of the [Het-s] prion, specifically in presence of their cognate ligands. The N-terminal motif of NWD2 is responsible for this prion induction. [NWD2] (Mus musculus) PubMed

 23889.

MTH1 catalyzes methyl group transfer from the co-factor to the substrate in a cation-dependent manner. [MTH1] (Mus musculus) PubMed

 23890.

Density functional theory calculations reveal that the protein backbone plays a significant role in controlling the environment of the active site coppers. (Mus musculus) PubMed

 23891.

There was almost no difference in growth and fertility of cellobiose dehydrogenase (CDH) mutants on various lignocellulose sources, except on crystalline cellulose, on which a 2-fold decrease in fertility of the mutants lacking P. anserina CDH1 (PaCDH1) and PaCDH2 was observed. [CDH1, CDH2, CDH3] (Mus musculus) PubMed

 23892.

key roles for IDC2 and IDC3 genesduring the formation of perithecia, the sexual fruiting bodies, are reported.[IDC2, IDC3] (Mus musculus) PubMed

 23893.

Allorecognition and cell death are dependent upon physical interaction between SEC-9 and PLP-1. [SEC-9 and PLP-1] (Mus musculus) PubMed

 23894.

a low molecular mass cutinase (designated TtcutA) from Thielavia terrestris was purified and biochemically characterized [cutA] (Mus musculus) PubMed

 23895.

radical-SAM enzyme Viperin catalyzes reductive addition of a 5'-deoxyadenosyl radical to UDP-glucose [viperin] (Mus musculus) PubMed

 23896.

the amphipathic helix present in the first alpha-helical domain (H1) of PspA is both necessary and sufficient for the targeting of this protein to lipid droplets [PspA] (Mus musculus) PubMed

 23897.

the lipids surrounding AqpZ, and the effects of a destabilizing mutation W14A (Schmidt and Sturgis, 2017) on lipid protein interactions, were investigated.[AqpZ] (Mus musculus) PubMed

 23898.

Tight junction-associated protein GEF-H1 in the neighbors of dividing epithelial cells is essential for adaptation of cell-cell membrane during cytokinesis. [GEF-H1] (Mus musculus) PubMed

 23899.

Data report the crystal structure of E. coli CFA synthase. The enzyme is a dimer in the crystal and in solution, with each subunit containing a smaller N-domain that associates tightly with a larger catalytic C-domain, even following cleavage of the inter-domain linker or co-expression of each individual domain. Efficient catalysis requires dimerization and proper linkage of the two domains. [cfa] (Mus musculus) PubMed

 23900.

Results provide evidence that PykM functions as a Mn-dependent enzyme. The loss of PykM has a negative impact on the capacity of the parental 2308 strain to utilize glucose, fructose, and galactose but not on its ability to utilize ribose, xylose, arabinose, or erythritol, and a pykM mutant displays significant attenuation in C57BL/6 mice suggesting its role in virulence. [PykM] (Mus musculus) PubMed

 23901.

In P. patens, the primary roles for MAX2 are in photomorphogenesis and moss early development rather than in strigolactone response.[MAX2] (Mus musculus) PubMed

 23902.

(TNF-R2) Ischemic preconditioning confers neuroprotection against transient cerebral ischemia through enhancement of TNF-R2 hippocampal expression. (Mus musculus) PubMed

 23903.

Although (mobile colistin resistance) mcr-1 confers a moderate level of polymyxin resistance, it is associated with a significant biological fitness cost in K. pneumonia [mcr-1]. (Mus musculus) PubMed

 23904.

Results show that the transcription factor CodY plays a primary role in promoting S. aureus hpf expression and acts upstream of SigB in favorable environments, but it represses hpf under suboptimal conditions of nutrients. [hpf, CodY, SigB] (Mus musculus) PubMed

 23905.

lnc-31 binds to the Rock1 mRNA as well as to the YB-1 protein and that translational activation requires physical interaction between the two RNA species. These results suggest a localized effect of YB-1 stabilization on the Rock1 mRNA. (long non-coding RNA-31) (Mus musculus) PubMed

 23906.

data indicate that despite Mks6 being a core transition zone component, it has tissue- or cell type-specific functions important for cilia formation and cilia sensory and signaling activities [Mks6] (Mus musculus) PubMed

 23907.

CaBP3-ARPC2 interaction helps to recruit CaBP3 along with myosin 1B to the phagocytic machinery that plays an indispensable role in E. histolytica phagocytosis.[CaBP3]ARPC2, a subunit of Arp2/3 complex, interacts with CaBP3 in a Ca(2+) -dependent manner.[ARPC2] (Mus musculus) PubMed

 23908.

c-di-GMP-bound PlzA functions as a positive regulator, whereas ligand-free PlzA acts as a negative regulator for glp expression [PlzA]. (Mus musculus) PubMed

 23909.

Noncatalytic urease appears to play an important role in oxidant protection [Urease]. (Mus musculus) PubMed

 23910.

RsmV is capable of sequestering RsmA and RsmF in vivo to activate translation of tssA1 [RsmV]. (Mus musculus) PubMed

 23911.

Overall, this study shows that the mechanisms of pilin antigenic variation are conserved between Gc and Mc [Pilin]. (Mus musculus) PubMed

 23912.

PhTET4 is a strict glycyl aminopeptidase, devoid of amidolytic activity toward other types of amino acids [PhTET4] (Mus musculus) PubMed

 23913.

the mph(A) gene confers azithromycin resistance to Salmonella Typhimurium [mph(A)] (Mus musculus) PubMed

 23914.

the OsSPL-mediated signaling pathway plays a crucial role in rice meiotic entry.[OsSPL] (Mus musculus) PubMed

 23915.

The level of the transcription factor MrpC correlated with multicellular mound formation and differentiation into spores [MrpC]. (Mus musculus) PubMed

 23916.

the Pcal_0041 protein contained a putative phosphofructokinase domain, it exhibited only low levels of phosphofructokinase activity [Pcal_0041] (Mus musculus) PubMed

 23917.

(cypin) Activation of brain cypin following traumatic brain injury significantly reduced fear conditioning after injury. (Mus musculus) PubMed

 23918.

The Salmonella-induced filament A protein (SifA) catalytic loop of WxxxE effectors is as important for salmonella-induced filaments formation and intracellular proliferation as the SKIP (SifA and kinesin interacting protein) interaction motif, or the CAAX motif for membrane anchoring of SifA. (Mus musculus) PubMed

 23919.

We reveal that sigma(I) affects expression of approximately 130 genes, of which 16 are directly regulated by sigma(I), including genes encoding proteins involved in iron homeostasis [sigma(I)]. (Mus musculus) PubMed

 23920.

Here, we show that the OmpR response regulator of one of the species found in cystic fibrosis respiratory infections, Burkholderia multivorans, is involved in the emergence of nonmucoid colony variants and is important for osmoadaptation by regulating several cell envelope component [OmpR]. (Mus musculus) PubMed

 23921.

These results suggest that H. volcanii GlpR functions as a direct negative regulator of fructose degradation during growth on carbon sources other than fructose, such as glucose and glycerol [GlpR]. (Mus musculus) PubMed

 23922.

Overexpression of OsNIP1;1 or OsNIP3;3 provides a route for arsenite to leak out of the stele, thus restricting arsenite loading into the xylem.[OsNIP1;1, OsNIP3;3] (Mus musculus) PubMed

 23923.

Tyrosine (but not S191) of PCNA1 is important for its nuclear localization and foci formation. [PCNA1] (Mus musculus) PubMed

 23924.

we show that two key regulators, MsaB and CodY, coordinate their functions to control the expression of capsule in response to nutrients [MsaB; CodY]. (Mus musculus) PubMed

 23925.

CarB is a persister gene that contributes to multidrug tolerance in P. aeruginosa [CarB] (Mus musculus) PubMed

 23926.

This study contributes to the understanding of how this critical enzyme for glycogen biosynthesis is regulated in the Firmicutes group. the ADP-glucose pyrophosphorylase from Bacillales seems to have distinctive insensitivity to regulation. [GlgC; GlgD] (Mus musculus) PubMed

 23927.

staphylococci secrete EssH to cleave peptidoglycan, thereby enabling T7bSS transport of proteins across the bacterial cell wall envelope [EssH]. (Mus musculus) PubMed

 23928.

Streptomyces coelicolor grows only aerobically, synthesizing two enzyme complexes for O2 reduction, the cytochrome bcc-aa3 cytochrome oxidase supercomplex and the cytochrome bd oxidase. We show in this study that the bacterium can survive with either of these respiratory pathways to oxygen [Cytochrome bd Oxidase]. (Mus musculus) PubMed

 23929.

In this work, we present evidence that the glutamate of the ERGSGR motif is required for proper HetN inhibition of heterocysts [HetN]. (Mus musculus) PubMed

 23930.

Our data demonstrate that XopAE85-10 is an XL box E3 ubiquitin ligase and provide insights into the structure and function of this effector family [xopAE]. (Mus musculus) PubMed

 23931.

SWEET11 and 15 show all the hallmarks of being necessary for seed filling with sucrose efflux functions at the nucellar projection.[SWEET11, SWEET15] (Mus musculus) PubMed

 23932.

T. thermophilus NurA and HerA exhibited an interfering effect on the repair of several instances of DNA damage in the cell, which is in contrast to the results in archaea. [NurA; HerA] (Mus musculus) PubMed

 23933.

Successful affibody tagging of the putative minor pilin PilA4 showed that it locates to the type IV pili in Synechocystis and that its extracellular availability depends on PilA1 [PilA1]. (Mus musculus) PubMed

 23934.

These results reveal the mechanism of FgSnc1 endosomal recycling by FgSnx41-FgSnx4 heterodimer which is essential for polarized growth and pathogenicity in F. graminearum.[Fgsnc1, FgSnx41, FgSnx4] (Mus musculus) PubMed

 23935.

This study reports that the Staphylococcal repressor protein StlSaPIBov1 (Stl) forms strong complex with human dUTPase. [Stl] (Mus musculus) PubMed

 23936.

MtCOPT1 transports copper (Cu) from the apoplast into nodule cells to provide Cu for essential metabolic processes associated with symbiotic nitrogen fixation.[MtCOP1] (Mus musculus) PubMed

 23937.

the identification and characterization of an endogenous long noncoding RNAs, TWISTED LEAF (TL), which is transcribed from the opposite strand of the R2R3 MYB transcription factor gene locus, OsMYB60, in rice, is reported.[TL] (Mus musculus) PubMed

 23938.

we have used a set of recently laboratory adapted ICAM-1-binding parasite isolates to generate sequence tags and, from these, to identify the full-length PfEMP1 being expressed by them. In a subset of the strains available we were able to produce validated, full-length var gene sequences and use these to conduct biophysical analyses of the ICAM-1 binding regions (Mus musculus) PubMed

 23939.

A critical role for the approximately 80 amino acids long, arginine-rich C-terminal domain of PE_PGRS3 in tuberculosis pathogenesis. Inorganic phosphate starvation induces PE_PGRS3 expression.[PE_PGRS3] (Mus musculus) PubMed

 23940.

ZnuA can bind as many as 5 zinc ions with a high affinity.ZnuA does not interact with AztD.[ZnuA] AztD cannot support transport of zinc into the cytoplasm, it likely functions to store zinc in the periplasm for transfer through the AztABCD system.[AztD] (Mus musculus) PubMed

 23941.

This study highlights Deinococcus polynucleotide kinase (HD-Pnk) as a bifunctional 3'- and 5'-end-healing enzyme that helps protect against killing by ionizing radiation [HD-Pnk]. (Mus musculus) PubMed

 23942.

Single-cell RNA sequencing (RNA-seq) assays identified Cyclin B3 (Ccnb3) as a putative mediator of zygotic genome activation. [Cyclin B3] (Mus musculus) PubMed

 23943.

binding thermodynamics of Mn2+, Zn2+ and Mg2+ to Cut190 and their effects on the catalytic activity and thermal stability [Cut190] (Mus musculus) PubMed

 23944.

significant role in protection from oxidative damage [Gdccr] (Mus musculus) PubMed

 23945.

OlHavcr2 was involved in innate immunity and adaptive immunity in medaka.[OlHavcr2] (Mus musculus) PubMed

 23946.

GrgA is an important regulator of both sigma(66)- and sigma(28)-dependent transcription in C. trachomatis [GrgA]. (Mus musculus) PubMed

 23947.

a 47-residue domain of the C terminus of the lytic transglycosylase (LT) SltF of R. sphaeroides is involved in the recognition of the rod chaperone FlgJ [SltF] (Mus musculus) PubMed

 23948.

Nickel-responsive transcriptional regulator (NikR) in the Brucella abortus binds directly to a specific DNA sequence within the promoter region of ATP-binding cassette transporter nikA in a metal-dependent manner to control gene expression. Deletion of nikR in B. abortus leads to alterations in the nickel-responsive expression of the genes encoding the putative nickel importer NikABCDE. (Mus musculus) PubMed

 23949.

When the 17-bp sequence present upstream of the sph2 promoter was deleted or scrambled, the fusion expression increased substantially. [Sph2] (Mus musculus) PubMed

 23950.

Sycrp2 is essential for twitching motility and it interacts with Sycrp1, a known cAMP receptor protein involved with twitching motility [Sycrp2] (Mus musculus) PubMed

 23951.

Our findings suggest that the regulatory proteases follow two pathways for regulated intramembrane proteolysis (RIP), where both the AlgO/MucP pathway and MucE/AlgW pathway are required in the wild-type strain but where the AlgO/MucP pathway can bypass the MucE/AlgW pathway in mucoid strains [MucP] (Mus musculus) PubMed

 23952.

Our results show that only M. tuberculosis DsbA is oxidized by VKOR [VKOR]. (Mus musculus) PubMed

 23953.

We isolated L. pneumophila mutants resistant to the inhibitory effect of 2-deoxyglucose (2DG) in macrophages, identifying a L. pneumophila hexose-phosphate transporter, UhpC, that is required for bacterial sensitivity to 2DG during infection. [UhpC] (Mus musculus) PubMed

 23954.

MlaD transfers phospholipids to MlaC.[MlaD][MlaC] (Mus musculus) PubMed

 23955.

the mutants of NaChBac channel with all possible combinations of aspartate and glutamate in the charged rings in position 191 and 192, were studied.[NaChBac] (Mus musculus) PubMed

 23956.

Salinity stress resulted in a sharp increase in H2O2 production, reaching a peak 3 h after salt treatment in the pumpkin-grafted cucumber. This enhancement was accompanied by elevated relative expression of respiratory burst oxidase homologue (RBOH) genes RbohD and RbohF and a higher NADPH oxidase activity.[RbohD] (Mus musculus) PubMed

 23957.

the present study demonstrates Hsp90AA1 embeds into the lipid bilayer through its C-terminal domain and the Hsp90AA1-lipid association potentially has a significant function in keeping membranes stabilization during stress conditions.[Hsp90AA1] (Mus musculus) PubMed

 23958.

absence of FakA leads to altered acetate metabolism and altered redox balance, as well as a change in intracellular amino acids [FakA]. (Mus musculus) PubMed

 23959.

We demonstrate that the alternative lipid A acyltransferase, LpxJ, from Rickettsia typhi and R. rickettsii catalyzes the addition of C16 fatty acid chains into the lipid A 3'-linked primary acyl chain [LpxJ]. (Mus musculus) PubMed

 23960.

We demonstrate that the alternative lipid A acyltransferase, LpxJ, from Rickettsia typhi and R. rickettsii catalyzes the addition of C16 fatty acid chains into the lipid A 3'-linked primary acyl chain [LpxJ] (Mus musculus) PubMed

 23961.

These results provide evidence that G0/G1 cell cycle arrest is a conserved function of norovirus VPg proteins that involves the N-terminal region of these proteins [VPg proteins]. (Mus musculus) PubMed

 23962.

Pcal_0970 is an extremely thermostable L-asparaginase with no detectable glutaminase activity [Pcal_0970] (Mus musculus) PubMed

 23963.

knockout of the luxS gene did not affect synthesis of N-acyl-homoserine lactones, lipolytic, and hemolytic activities of S. proteamaculans 94 [luxS] (Mus musculus) PubMed

 23964.

Salmonella SifA protein interacts with Arl8b host protein.[SifA]The role of SseG protein in the formation of membrane tubules in host cells.[SseG] (Mus musculus) PubMed

 23965.

The srtA gene of Brochothrixthermosphacta consisted of 636 nucleotides encoding a 211 amino acid long protein with a calculated molecular weight of 23.4 kDa. [srtA] (Mus musculus) PubMed

 23966.

Findings indicate that PG1842 may play a significant role in the activation/maturation of gingipains in Porphyromonas gingivalis. [PG1842] (Mus musculus) PubMed

 23967.

Data show that YtfE interacts with Dps in a manner that serves to protect E. coli from RIC protein-induced reactive oxygen species. [Dps, YtfE] (Mus musculus) PubMed

 23968.

altered CppA activity reduces chlamydial growth, and CppA function is likely crucial for early differentiation events [CppA] (Mus musculus) PubMed

 23969.

The work described here shows that a codY null mutant of a hypervirulent (ribotype 027) strain is even more virulent than its parent in a mouse model of infection and that the mutant expresses most sporulation genes prematurely during exponential growth phase.[codY] (Mus musculus) PubMed

 23970.

Hog1 protects C. glabrata from growth inhibition caused by weak organic acids and low pH.Hog1 has an important role in the confrontation of C. glabrata with the common vaginal flora (Hog1). (Mus musculus) PubMed

 23971.

XdrA and CodY have broad binding sites that overlap extensively in the capsule promoter region. These results suggest that XdrA plays a secondary role in capsule regulation by promoting CodY repression of the cap genes [XdrA; CodY]. (Mus musculus) PubMed

 23972.

Here, we characterize the rffG gene in P. mirabilis, demonstrating that it is required for the production of large lipopolysaccharide-linked moieties necessary for wild-type cell envelope integrity [rffG]. (Mus musculus) PubMed

 23973.

characterization of a novel Ser/Thr phosphatase that acts to dephosphorylate a Ser/Thr kinase that is encoded in the same operon [YegK] (Mus musculus) PubMed

 23974.

Mhp597 is a dynamic secreted nuclease involved in cytotoxicity, inflammation and immunosuppression [Mhp597] (Mus musculus) PubMed

 23975.

Double deletion of meq and lorf9 genes overcome lymphoid organ atrophy induced by meq-deletion Marek's disease virus. [lorf9]. (Mus musculus) PubMed

 23976.

PKS14-catalyzed polyketide enhances virulence and pathogenicity of B. bassiana on insects.[PKS14] (Mus musculus) PubMed

 23977.

Specific amino acid substitutions in Hpk2 affected autophosphorylation, phosphotransfer, oligomerization, and hemin binding [Hpk2]. (Mus musculus) PubMed

 23978.

Study reveals the structural and dynamic mechanisms of drug resistance for the Y56H/D168A NS3 protease, a double-site RAS variant that has been identified in patients who failed therapy with protease inhibitor (PI)-containing regimens. Y56H substitution disrupts favorable stacking interactions with the neighboring catalytic His57. This indirect mechanism of resistance threatens to cause multi-PI failure. [NS3] (Mus musculus) PubMed

 23979.

Determination of glycosylation sites and types for T. reesei cellobiohydrolase I (cellobiohydrolase I). (Mus musculus) PubMed

 23980.

tRNA aminoacylation was inhibited in self S-RNase-treated or MdPPa-silenced pollen tubes, resulting in the accumulation of uncharged tRNA.[S-RNase, MdPpa] (Mus musculus) PubMed

 23981.

Overexpressed NtPR1a in susceptible tobacco plants enhancing resistance to the bacterial pathogen R. solanacearum (PR1a). (Mus musculus) PubMed

 23982.

Clumping factor A (ClfA) mediates adhesion to endothelial cell surface molecules and (sub)endothelial matrix proteins including fibrinogen, fibrin, fibronectin and von Willebrand factor. (Mus musculus) PubMed

 23983.

studies not only reveal important functions of MoMkk1-MoPpe1-MoSap1 interactions in growth and pathogenicity of the blast fungus, but also highlight the complexity of regulatory networks involving conserved yet novel regulatory mechanisms of cell wall integrity and TOR signaling (Sap1) (Mus musculus) PubMed

 23984.

KKT4 has key functions required for driving chromosome segregation. (Mus musculus) PubMed

 23985.

Study determined the crystal structure of Bc- TubR and identified the consensus sequence for Bc-TubR binding in the promoter region of tubRZ. The imperfect Bc-TubR recognition sequences lead to a relatively flexible segrosome structure, thereby achieving transient complex formation with cytomotive filaments of TubZ. [TubR, TubZ] (Mus musculus) PubMed

 23986.

Results reveal that the HIV-1 PR has evolved bi-functional S2 and S2' subsites to accommodate the steric effects imposed by a P1' proline on the orientation of P2 and P2' substrate side chains. [PR] (Mus musculus) PubMed

 23987.

The data presented here are consistent with a model of Msp as a large-diameter beta-barrel porin.[Msp] (Mus musculus) PubMed

 23988.

SSL13 induced an oxidative burst and degranulation in neutrophils.SSL13 specifically binds and activates FPR2.[SSL13] (Mus musculus) PubMed

 23989.

A mutant deleted for STM14_1829 showed the most severe motility defect, indicating that among the three paralogs, STM14_1829 is a key protein required for wild-type motility.[STM14_1829] (Mus musculus) PubMed

 23990.

results further confirmed the regulatory function of Ran1 on amitosis and suggested a novel role of Ran1 in cytokinesis and the alignment of cytoplasmic microtubules in T. thermophile [ran1] (Mus musculus) PubMed

 23991.

AhlC tetramer dissociates, binds a single membrane leaflet, recruits AhlB promoting soluble to pore transition, prior to AhlA binding to form the active hydrophilic lined pore.[AhlA,AhlB,AhlC] (Mus musculus) PubMed

 23992.

A new role for the Crz2 protein: the regulation of processes controlling the ability of C. albicans to efficiently proliferate within the host. Crz2 binds to the promoter of mannosyltransferase- and cell wall protein-encoding genes.[ Crz2] (Mus musculus) PubMed

 23993.

C252Y mutation increases AtpA protein levels, intracellular ATP synthase activity, intracellular ATP abundance and transcription of the genes. [AtpA] (Mus musculus) PubMed

 23994.

Thiaminase I cleaves phosphorylated thiamine and toxic analogs, which releases precursors that can then be used for thiamine synthesis. [ThiA(BTH_II1306)] (Mus musculus) PubMed

 23995.

Both the GRA7-dependent activation of the inflammatory response and the parasite burden are important in Neospora virulence.[GRA7] (Mus musculus) PubMed

 23996.

CsLFY has a novel function in regulating shoot meristem maintenance through interaction with CsWUS.[CsLFY, CsWUS] (Mus musculus) PubMed

 23997.

Ten race-specific P alleles conditioned the white seed phenotype, and each causative mutation affected at least one bHLH domain required for color expression.[P gene] (Mus musculus) PubMed

 23998.

Cultured bloodstream Trypanosoma brucei adapt to life without mitochondrial translation release factor 1. (Mus musculus) PubMed

 23999.

Here, the authors show that in the model bacterium Bacillus subtilis the general stress transcription factor SigB is essential for halting detrimental overgrowth of mature biofilm and for triggering dispersal when nutrients become limited.[SigB] (Mus musculus) PubMed

 24000.

The gene thn1 is transcriptionally regulated in response to mating with a role in clamp cell development and hydrophobin gene transcription. [ thn1] (Mus musculus) PubMed

 24001.

[DGD1] DGD1 contributes to effective nodule organogenesis and nitrogen fixation by affecting the synthesis and content of DGDG during symbiosis. (Mus musculus) PubMed

 24002.

the epigenetic role of VRN3 and H3K4me3/H3K27me3 in vernalization and reveal genes underlying epigenetic memory, laying the foundation for further study.[VRN3] (Mus musculus) PubMed

 24003.

FgArb1 interacts with the mitogen-activated protein kinase (MAPK) FgSte7, and partially modulates plant penetration by regulating the phosphorylation of FgGpmk1.[FgArb1] (Mus musculus) PubMed

 24004.

This paper describes how an enzyme not belonging to the GMC oxidoreductase family, CcPDH, can activate lytic polysaccharide monooxygenases [CcPDH]. (Mus musculus) PubMed

 24005.

SFI5 suppresses plant immunity by interfering with immune signalling components after activation by Calmodulins.[SFI5] (Mus musculus) PubMed

 24006.

[ChilV3] the expression of the defense gene ChiIV3 is controlled through multiple modes of regulation, and WRKY40 directly binds to the W4-box element of the ChiIV3 promoter region for its transcriptional regulation (Mus musculus) PubMed

 24007.

NBAD-S was exported and deposited into the extracellular matrix of the brown spot areas before cell death and tanning occurs through gradual export of NBAD precursors (dopamine and b-alanine) from veins.[NBAD-S] (Mus musculus) PubMed

 24008.

Study find that cotranslational folding of a segment corresponding to the first four of the eight beta-helix coils in the protein PENT produces enough force to release ribosome stalling and that folding starts when this unit is ~35 residues away from the P-site, near the distal end of the ribosome exit tunnel. An additional folding transition is seen when the whole PENT moiety emerges from the exit tunnel. [PENT] (Mus musculus) PubMed

 24009.

The authors showed that a Staphylococcus aureus sgtB transposon mutant, with the monofunctional peptidoglycan glycosyltransferase SgtB inactivated, displayed a 4-fold increase in the minimum inhibitory concentration of oxacillin, suggesting that alterations in the peptidoglycan structure could help bacteria compensate for the lack of lipoteichoic acid.[sgtB] (Mus musculus) PubMed

 24010.

Reversible membrane sequestration of DraG was independent of AmtB proteins and occurred even under non-diazotrophic conditions. [DraG] (Mus musculus) PubMed

 24011.

OsLRR-RLK1 may be involved in the perception of herbivory-associated molecular patterns.[OsLRR-RLK1] (Mus musculus) PubMed

 24012.

Absence of ppr3, ppr4, ppr6 or ppr10 can result in nonsexual flocculation and filamentous growth of cells. [ppr10] (Mus musculus) PubMed

 24013.

PPS1 is required for specific editing sites in nad3 in rice.[PPS1, nad3] (Mus musculus) PubMed

 24014.

SppA protein indicated that it possessed hexose-phosphate phosphohydrolase activity, with preferences for fructose-1-phosphate and, to a lesser degree, fructose-6-phosphate. SppR, a DeoR family regulator, repressed the expression of the sppRA operon to minimum levels in the absence of the fructose-derived metabolite fructose-1-phosphate and likely also fructose-6-phosphate.[SppRA] (Mus musculus) PubMed

 24015.

the importance of duNLRP3 in regulating the inflammatory response and influencing the progression of avian pathogenic Escherichia coli infection (NLRP3) (Mus musculus) PubMed

 24016.

MdMYB88 and MdMYB124 positively regulate cold hardiness and cold-responsive gene expression under cold stress by C-REPEAT BINDING FACTOR (CBF)-dependent and CBF-independent pathways.[MdMYB88, MdMYB124, CBF] (Mus musculus) PubMed

 24017.

Data demonstrate that these viruses carry formerly undescribed Mx resistance mutations in the NP that mediate efficient escape from human MxA. [NP] (Mus musculus) PubMed

 24018.

Fusarium fujikuroi ABA1 is the major conidiation-specific TF gene targeted by global regulators. [ABA1] (Mus musculus) PubMed

 24019.

This work presents the 1.8 A crystal structure of superoxide dismutase, a manganese containing superoxide dismutase from Xanthomonas citri subsp. citri. [manganese superoxide dismutase] (Mus musculus) PubMed

 24020.

OsMADS57 and OsTB1 conversely affect rice chilling tolerance via targeting OsWRKY94.[OsMADS57, OsTB1, OsWRKY94, D14] (Mus musculus) PubMed

 24021.

BDCP and Vps8 proteins are essential for parasite survival.BDCP and Vps8 are associated to the complex formed by Vps11 and localize to the endomembrane system in T. gondii.[Vps8][BDCP] (Mus musculus) PubMed

 24022.

Study reports the 2.8 A resolution crystal structure of the variable protein from the T. aquaticus prophage diversity-generating retroelement, called TaqVP, and confirm that it has a C-type lectin-fold.[TaqVP] (Mus musculus) PubMed

 24023.

[HicA, HicB] HicA is a toxin with ribonuclease activity and HicB has two domains: the COOH-terminal one that binds the operator and the NH2-terminal one that inhibits the toxin (Mus musculus) PubMed

 24024.

NapA displays Michaelis-Menten kinetics (Fig. 2), with a calculated maximum velocity (Vmax) of 3.40 +/- 0.10 mumoles min-1 mg protein-1 and a KM for NO3- of 3.40 +/- 0.44 muM. [NapA] (Mus musculus) PubMed

 24025.

PxylOR8, PxylOR41 and PxylOR45 are localized in long trichoid sensilla. Functional analyses on the three pheromone receptor genes were then performed. PxylOR41 was tuned to two minor pheromone components Z9-14:Ac, Z9-14:OH, and their analog Z9-14:Ald. PxylOR8 and PxylOR45 did not respond to any tested pheromone components and analogs.[OR8,OR41,OR45] (Mus musculus) PubMed

 24026.

Moderate inhibition of matrix metalloproteinases (Mmp1, Mmp2, Mmp3) activity via inhibitor treatments delayed fat body cell dissociation and ovary development, while severe inhibition blocked these developmental processes and eventually led to pupal lethality.[Mmp3] (Mus musculus) PubMed

 24027.

VqsA is an important player in quorum sensing (QS) regulation and pathogenesis and may be the third master QS regulators involved in sensing environmental signals by vibrios to coordinate QS responses [VqsA]. (Mus musculus) PubMed

 24028.

a short DivL homologue and ClpXP regulate CtrA in R. capsulatus [DivL] (Mus musculus) PubMed

 24029.

These results imply fundamentally different wiring of auxin transport in Brachypodium roots and reveal an essential role of BdAUX1 in a broad spectrum of developmental processes.[BdAUX1] (Mus musculus) PubMed

 24030.

Gene deletion of dicarboxylic acid transporter (DcuE) decreases the uptake of l-malate rather than fumarate in Actinobacillus succinogenes. DcuE complement anaerobic growth of Escherichia coli on l-malate or fumarate; thus, the transporter is characterized in E. coli heterologously. DcuE catalyses the reversible exchange of three C(4) -dicarboxylates - l-malate, fumarate and succinate. (Mus musculus) PubMed

 24031.

HilD and PhoP independently regulate the expression of grhD1, a novel gene required for Salmonella Typhimurium invasion of host cells [HilD][PhoP] (Mus musculus) PubMed

 24032.

The specific binding of ANCR with EZH2 suppressed RUNX2, thereby inhibiting osteogenesis.[lncRNA-ANCR] (Mus musculus) PubMed

 24033.

FgSec2A acts as a FgRab8 guanine nucleotide exchange factor and is necessary for polarized growth, DON production and pathogenicity in F. graminearum. [FgSec2A, FgRab8] (Mus musculus) PubMed

 24034.

Both overexpression strains were found to tolerate twice as high concentrations of added H2O2 as the control strain, indicating that overexpression of either NpDps2 or NpDps5 will enhance the capacity for H2O2 tolerance.[ NpDps2, NpDps5] (Mus musculus) PubMed

 24035.

IST is bound to STAT1 dimers but more efficiently assembled with STAT1 tetramers, which are essential for effective interferon-gamma responsiveness during infection. [IST] (Mus musculus) PubMed

 24036.

Data showed all 11 LTA epitopes were immunogenic; epitope 7 ((105)SPHPYEQEVSA(115)) induced greater titers of anti-LT antibodies which neutralized LT enterotoxicity more effectively. [LTA] (Mus musculus) PubMed

 24037.

Gas3 acts as a pH-responsive cell wall-remodeling enzyme involved in resistance to extreme pH.[Gas3] (Mus musculus) PubMed

 24038.

Ms0179 role in the biofilm formation.[Ms0179] Ms0180 role in the biofilm formation.Ms0180 positively regulates a D-mannitol metabolism and transportation related gene cluster.[Ms0180] (Mus musculus) PubMed

 24039.

key CLE domain amino acids and tri-arabinosylation (TaP) at proline 7 modifications to MtCLE12 and MtCLE13 are essential for SUNN-dependent autoregulation of nodulation.[MtCLE12, MtCLE12, SUNN] (Mus musculus) PubMed

 24040.

Results show that FtsY forms nucleotide-specific homodimers on a Lipid bilayer as well as on the cell membrane, stimulating its GTPase Activity. Its shares similar interface as the FtsY/Ffh heterodimer. [FtsY] (Mus musculus) PubMed

 24041.

Our study in limited by the small number of patients with ulcers. Nevertheless, it represents an advance in biomedical science as it suggests that infection with cagG+ strains could be benefit biomarker for reduced risk of gastric ulceration, whereas strains carrying the orf17 might increase the risk of duodenal ulceration (Mus musculus) PubMed

 24042.

[Lxx18460] Lxx18460 may act important roles in the course of infection in sugarcane (Mus musculus) PubMed

 24043.

Study trace the light-driven secondary structural rearrangement of Cph2 tongue region, and found a translational motion of the PHY domain. These results demonstrate a common light response in the photosensory modules of phytochromes, orchestrated solely by the GAF-PHY bidomain independent of further quaternary interactions or the nature of downstream effector domains. [Cph2] (Mus musculus) PubMed

 24044.

our results suggest a possible relationship between PMT1 and TED1 regarding lifespan regulation and the endoplasmic reticulum stress response [PMT1]. (Mus musculus) PubMed

 24045.

Host MMP-9 is a substrate of the zinc metalloproteinase Zpx during Cronobacter turicensis infections.[Zpx] (Mus musculus) PubMed

 24046.

The cyanophycin-synthesizing enzyme CphA in the nonactive state localizes diffusely in the cytoplasm. When cyanophycin synthesis is triggered, active CphA first aggregates into foci and then covers the surface of mature cyanophycin granules. (Mus musculus) PubMed

 24047.

we identified the transporter gene DdvK responsible for the uptake of 5,5'-dehydrodivanillate, a lignin-derived biphenyl compound [DdvK] (Mus musculus) PubMed

 24048.

overexpression of DEC1 blocked myogenesis by inhibiting MyoG promoter activity in bovine. (Mus musculus) PubMed

 24049.

A combination of pull-downs and proteomics analyses led to the discovery of a mycobacterial protein, HadD, displaying highly specific interactions with the dehydratase HadAB of fatty acid synthase type II. In vitro activity assays and homology modeling showed that HadD is, like HadAB, a hot dog folded (R)-specific hydratase/dehydratase. [HadD] (Mus musculus) PubMed

 24050.

LGF1 regulates C30 primary alcohol synthesis, which is necessary for abundant epicuticular wax platelets, leaf hydrophobicity and gas films on submerged leaves.[LGF1] (Mus musculus) PubMed

 24051.

IdeR directly regulates 12 targets involved in other biological processes, including morphological differentiation, secondary metabolism, carbohydrate metabolism, and the tricarboxylic acid (TCA) cycle.[IdeR] (Mus musculus) PubMed

 24052.

Study found that conformational changes between the ATPase and the protease domain of TmFtsH are driven by thermalmotions and onlyweakly coupled to ATP. TmFtsH adopts five discrete, well defined states during closing and opening cycles, which remain to be structurally resolved. [FtsH] (Mus musculus) PubMed

 24053.

ATR2 plays a supplementary role in Aluminum tolerance in rice.[ATR2] (Mus musculus) PubMed

 24054.

These results show a virulence function for Scp2 during penetration that is probably carried out by Scp2 in peroxisomes.[Scp2] (Mus musculus) PubMed

 24055.

Transcript profiling and functional characterization in heterologous systems identified VisHKT1;1 as the best candidate gene for controlling leaf Na(+) exclusion.[HKT1;1] (Mus musculus) PubMed

 24056.

CapC is a novel virulence factor in C. jejuni that contributes to adhesion and invasion of the intestinal epithelium [CapC]. (Mus musculus) PubMed

 24057.

co-evolution of U. maydis with its host plant extended the endogenous function of UmFly1 towards the modulation of plant chitinase activity to promote infection.[UmFly1] (Mus musculus) PubMed

 24058.

Sodium-motive force-dependent drug antiport in the ATP-bound state of LmrA and the ion stoichiometry of this reaction.[LmrA] (Mus musculus) PubMed

 24059.

Nucleotide binding and hydrolysis controls HSP60 conformation.[HSP60] (Mus musculus) PubMed

 24060.

Reassessing the Structure and Function Relationship of the O2 Sensing Transcription Factor FNR [FNR] (Mus musculus) PubMed

 24061.

interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis [Myb1][cyclophilin 1] (Mus musculus) PubMed

 24062.

This work provides insight into the role of the RNA decay factor Xrn1/XRN1 as a post-transcriptional regulator of autophagy.[XRN1] (Mus musculus) PubMed

 24063.

identification of the novel colistin resistance gene mcr-5 in an A. hydrophila isolate from the faeces of a backyard pig [mcr-5] (Mus musculus) PubMed

 24064.

Our results show that MgrA can modulate biofilm structuring and development by repressing the production of phenol-soluble modulins in S. aureus [MgrA]. (Mus musculus) PubMed

 24065.

This study revealed the genetic determinants of carbofuran degradation in Sphingomonas sp. strain CDS-1. cehACDS-1 and cfdCCDS-1 are responsible for the conversion of carbofuran and carbofuran phenol, respectively [cehA; cfdC]. (Mus musculus) PubMed

 24066.

Invasin is differentially expressed under conditions relevant for pathogenesis.[invasion] (Mus musculus) PubMed

 24067.

this study shows that cytotoxic necrotizing factor 1 down-regulates CD36 transcription in macrophages to Induce Inflammation during acute urinary tract infections (Mus musculus) PubMed

 24068.

MdWRKY9 plays a critical role in regulating the expression of MdDWF4.[MdWRKY9, MdDWF4] (Mus musculus) PubMed

 24069.

Conformational dynamics of the ABC transporter McjD seen by single-molecule FRET. (Mus musculus) PubMed

 24070.

The biomass of the silenced lines showed higher digestibility supporting a causative role of the BdGT43A gene, suggesting that it might form a good target for improving straw digestibility in crops.[BdGT43A] (Mus musculus) PubMed

 24071.

OsCERK1 is an lipopolysaccharide (LPS) receptor/co-receptor and that the LPS perception systems of rice and Arabidopsis are significantly different.[OsCERK1] (Mus musculus) PubMed

 24072.

SIP1 interacts with Trx1, allowing Trx1 to specifically target Ehd1, altering H3K4me3 levels, increasing Ehd1 expression and thereby promoting flowering (SIP1). (Mus musculus) PubMed

 24073.

mutation of a putative ubiquitin-conjugation enzyme (E2) binding site abolished XopK-induced degradation of OsSERK2 and compromised XopK-dependent virulence.[Xopk] (Mus musculus) PubMed

 24074.

three respiratory burst oxidase homologs (Rboh) and one calcium-dependent protein kinase (CDPK) were identified as key factors for the activation of immunity in Medicago nodules.[MtCDPK5] (Mus musculus) PubMed

 24075.

a promiscuous 2,3-oxidosqualene cyclase from rice (Oryza sativa) (OsOS) that synthesizes a novel pentacyclic triterpene orysatinol as its main product, is reported.[Osos] (Mus musculus) PubMed

 24076.

Therefore, our findings unveil LincU as a conserved lncRNA that intrinsically restricts MAPK/ERK activity and maintains the naive state of ESCs. (Mus musculus) PubMed

 24077.

These in vitro findings suggest that, under iron-limiting conditions, iutA transcription in Vibrio furnissii is artfully regulated both by IutR, acting as a direct repressor of iutA, and by AERO, acting as an effector for IutR, leading to the derepression of iutA transcription.[lutR, iutA] (Mus musculus) PubMed

 24078.

Loss of RamR or OqxR reduced envelope permeability in K. pneumonia. OqxR loss specifically activated OqxAB efflux pump production which reduced fluoroquinolone susceptibility but had little impact on beta-lactam susceptibility. (Mus musculus) PubMed

 24079.

emergence of highly resistant pfdhfr/pfdhps alleles in the Democratic Republic of the Congo [dhfr; dhps] (Mus musculus) PubMed

 24080.

findings show that goose PKR is an important antiviral IFN-stimulated gene, involved in the antiviral innate immune defense to Newcastle Disease Virus in geese (Mus musculus) PubMed

 24081.

This study reports that two peptides of Vigna unguiculata-lipid transfer protein are responsible for human salivary alpha-amylase inhibition. [lipid transfer protein] (Mus musculus) PubMed

 24082.

MhuD-R26S variant is an important tool for further probing the mechanism of action of MhuD and for studying the fate of the MhuD product in mycobacterium[MhuD] (Mus musculus) PubMed

 24083.

We identified a novel plasmid-mediated colistin resistance gene named mcr-7.1 in K. pneumoniae in China [mcr-7.1] (Mus musculus) PubMed

 24084.

Crystal structures of Succinate-Acetate Permease (SatP)_Citrobacter koseri in complex with multiple acetates at 1.8 A reveal that the acetate pathway consists of four acetate-binding sites aligned in a single file that are interrupted by three hydrophobic constrictions. [Succinate-Acetate Permease] (Mus musculus) PubMed

 24085.

Doda2 expression and role in the betalain synthesis.Doda2 amino acid residues essential for betalamic acid production.[Doda2] (Mus musculus) PubMed

 24086.

ETV7 expression alters mTOR signaling (ETV7). (Mus musculus) PubMed

 24087.

results indicate that CgRpn4 acts as a transcriptional activator of proteasomal genes [Rpn4] (Mus musculus) PubMed

 24088.

FinR played a positive role and cooperated with the NicR repressor in bacterial nicotinic acid degradation via regulating the expression of nicC and nicX operons. [FinR] (Mus musculus) PubMed

 24089.

the ABC transporter OpuF mediates the import of glycine betaine, proline betaine, homobetaine, and the marine osmolyte dimethylsulfoniopropionate [OpuF] (Mus musculus) PubMed

 24090.

findings on the structural and functional characterization of CMP-N-acetylneuraminate synthetase (CMAS), a key enzyme in the incorporation pathway, from Vibrio cholerae are reported. [CMP-N-acetylneuraminate synthetase (CMAS)] (Mus musculus) PubMed

 24091.

BAK1(MD15G1412700) helps to regulate the growth of apple tree through activation the brassinosteroid and ethylene signals, xylem production, and stress responses.[BAK1] (Mus musculus) PubMed

 24092.

our study proved that the expression of Hsp27/P53 differed across the testis developmental stages and the expression of P53 was higher in the testis of cattle-yak, which suggested that the infertility of cattle-yak may be caused by the upregulation of P53. (Mus musculus) PubMed

 24093.

A novel resistance gene, named poxtA, encoding a protein of the antibiotic resistance ABC-F lineage, was identified in the genome of an MRSA of clinical origin [poxtA] (Mus musculus) PubMed

 24094.

Specific mutation patterns in PBP2/MtrR/PorB were associated with specific gonococcal genogroups and penicillin susceptibility [PBP2; MtrR; PorB] (Mus musculus) PubMed

 24095.

Adcy9 inactivation protects against atherosclerosis, but only in the absence of cholesteryl ester transfer protein (CETP) activity. (Mus musculus) PubMed

 24096.

OmpC is the key receptor-binding protein for phage GH-K3.[OmpC] (Mus musculus) PubMed

 24097.

Biochemical characterization and mutational analysis of alanine racemase from Clostridium perfringens [alanine racemase] (Mus musculus) PubMed

 24098.

Deletion of RGS1 and COS1 reduced the pathogenicity of M. oryzae. [RGS1 and COS1] (Mus musculus) PubMed

 24099.

CsMYB6-CsTRY complex negatively regulates fruit trichome formation in cucumber.[CsMYB6] (Mus musculus) PubMed

 24100.

Crystal structures of K. pneumoniae acetolactate decarboxylase (KpALDC) were determined. Structures feature a conserved active site with a bound Zn2+ ion. [acetolactate decarboxylase] (Mus musculus) PubMed

 24101.

This study shows that the rate of RNA cleavage by D. radiodurans RNA polymerase (RNAP) depends on the structure of the (mis)matched RNA 3'-nucleotide and its contacts with the active site. [RNA polymerase] (Mus musculus) PubMed

 24102.

The ATPase activity of H(+)-FOF1-ATP synthase (FOF1) is down-regulated by several mechanisms. Mutation Q259L in subunit beta in Bacillus subtilis ATP synthase attenuates ADP-inhibition. [ATP synthase (FOF1)] (Mus musculus) PubMed

 24103.

circHECTD1 functions as an endogenous MIR142 (microRNA 142) sponge to inhibit MIR142 activity, resulting in the inhibition of TIPARP (TCDD inducible poly[ADP-ribose] polymerase) expression with subsequent inhibition of astrocyte activation via macroautophagy/autophagy.[circHECTD1] (Mus musculus) PubMed

 24104.

This study determined the crystal structure of P. acnes beta-ketoacyl acyl carrier protein synthase (KAS III) at the resolution of 1.9A . [beta-ketoacyl acyl carrier protein synthase III] (Mus musculus) PubMed

 24105.

Nodulation and N2 fixation were significantly impaired by mutation of the bcp gene in A. caulinodan. [bcp] (Mus musculus) PubMed

 24106.

miR160 plays a crucial role in local defense and systemic acquired resistance responses during the interaction between potato and Phytophthora infestans. [mir160] (Mus musculus) PubMed

 24107.

Silencing of lncRNA TCONS_00088786 can inhibit the development of interstitial fibrosis via reducing expression of miR-132, which may be a target for treating renal interstitial fibrosis. (Mus musculus) PubMed

 24108.

This study demonstrated that in-vivo turnover frequency of the cyanobacterial NiFe-hydrogenase during photohydrogen production outperforms in-vitro systems. [NiFe-hydrogenase] (Mus musculus) PubMed

 24109.

AcfC contributes to the chemotactic response of WT V. cholerae and plays an important role in defining the overall distribution of the organism within the intestine [AcfC] (Mus musculus) PubMed

 24110.

Data report crystal structure of the conserved and functional C-terminal portion (aa289-709) of AKMT which dimerizes via a unique intermolecular interface mediated by the C-terminal tetratricopeptide repeat-like domain together with a specific zinc-binding motif that is absent from all other KMTs. Disruption of AKMT dimerization impaired both its enzyme activity and parasite egress from infected host cells in vivo. [AKMT (Mus musculus) PubMed

 24111.

Study identified a novel lncRNA Flatr, as a member of the core Treg lncRNA transcriptome. Flatr expression anticipates Foxp3 expression during in vitro Treg conversion, and Flatr-deficient mice show a mild delay in in vitro and peripheral Treg induction. These results implicate Flatr as part of the upstream cascade leading to Treg conversion and may provide clues as to the nature of this process.[Flatr] (Mus musculus) PubMed

 24112.

Together, these results are consistent with Cdc15 playing an essential role in signalling for mitotic exit, cytokinesis and cell separation in Candida albicans.[Cdc15] (Mus musculus) PubMed

 24113.

Taken together, this is the first functional analysis of NtLTP4, and proves that NtLTP4 positively regulates salt and drought stresses in Nicotiana tabacum.[ NtLTP4] (Mus musculus) PubMed

 24114.

observations show that A-LPS modification contributes to OM(V) sorting and 'protective secretion' of PPAD. (Mus musculus) PubMed

 24115.

The Ruminococcus flavefaciens cohesin ScaB5-dockerin ScaA complex has an elliptical architecture similar to previously described complexes from a variety of ecological niches.[ScaA, ScaB] (Mus musculus) PubMed

 24116.

Prevalence of Single and Multiple Natural NS3, NS5A and NS5B Resistance-Associated Substitutions in Hepatitis C Virus Genotypes 1-4 in Italy. (Mus musculus) PubMed

 24117.

These cross-link data and computational docking of Dnmt2 and tRNA(Asp) reveal Q34 positioned adjacent to the S-adenosylmethionine occupying the active site, suggesting that the observed increase of Dnmt2 catalytic efficiency by queuine originates from optimal positioning of the substrate molecules and residues relevant for methyl transfer.[Dnmt2] (Mus musculus) PubMed

 24118.

Enhanced expression of RDR1 is correlated with reduced Tomato leaf curl Gujarat virus titer and an enhanced level of methylation of the viral promoter in the recovered leaves.[RDR1] (Mus musculus) PubMed

 24119.

The binding of HbGF14a to HbRZFP1 interferes with the interaction of HbRZFP1 with the HRT2 promoter, thereby repressing the protein-DNA binding between them. [ HRT2 ] (Mus musculus) PubMed

 24120.

C8orf37 KO mice exhibited progressive and simultaneous degeneration of rod and cone photoreceptors but no non-ocular phenotypes. (Mus musculus) PubMed

 24121.

Using atomic force microscopy and single-round fast kinetics translocation assays this study determined the localization and dynamics of diffusing and translocating SpoIIIE complexes on DNA with or without specific octameric sequences. [SpoIIIE] (Mus musculus) PubMed

 24122.

we present two high-resolution structures of the binding domain of subtype BoNT/A3 (HC/A3) and BoNT/A4 (HC/A4) at 1.6A and 1.34A resolution, respectively. The structures of both proteins share a high degree of similarity to other known BoNT HC domains whilst containing some subtle differences, and are of benefit to research into therapeutic neurotoxins with novel characteristics. (Mus musculus) PubMed

 24123.

Study have detected over 50 substitutions affecting the function/stability of Vip3Af1 protein, with 19 of them compromising protein expression or, alternatively, rendering such proteins unstable that were degraded immediately afer their expression. [Vip3Af1] (Mus musculus) PubMed

 24124.

Hippo/MST downregulation has a critical role in PAX3-FOXO1-positive rhabdomyosarcoma tumorigenesis [Hippo] (Mus musculus) PubMed

 24125.

Data find that a single MutL dimer can activate latent UvrD monomer helicase activity. However, MutL stimulates UvrD dimer helicase activity. MutL enhances the DNA-unwinding processivity of UvrD. Hence, MutL acts as a processivity factor by binding to and presumably moving along with UvrD to facilitate DNA unwinding. [MutL, UvrD] (Mus musculus) PubMed

 24126.

the HRM dissociation profiles of msp1 and msp2 amplicons were determined and validated against parasite isolates from malaria patients. The msp1 and msp2 profiles of both laboratory and clinical isolates were reproducibly differentiated by HRM (Mus musculus) PubMed

 24127.

Results indicate that lncRNA-1 represents a new regulatory RNA that plays a relevant role during the early stages of osteogenesis. lncRNA-1 that exhibited increased expression during osteogenesis and was downregulated during myogenesis. [lncRNA-1] (Mus musculus) PubMed

 24128.

It is demonstrated in our study that a maize glycosyltransferase, UFGT2, involved in modifying flavonols, contributes to improving plant tolerance to abiotic stresses.[UFGT2] (Mus musculus) PubMed

 24129.

crystal and electron cryo-tomography structures of Mgm1 from Chaetomium thermophilum; Mgm1 consists of a GTPase (G) domain, a bundle signalling element domain, a stalk, and a paddle domain that contains a membrane-binding site (Mus musculus) PubMed

 24130.

a function for YlmD and YlmE in the control of sporulation-specific cell division in S. coelicolor [ylmE][ylmD] (Mus musculus) PubMed

 24131.

Eat1-catalyzed ethyl acetate production occurs in mitochondria. [Eat1] (Mus musculus) PubMed

 24132.

We provide evidence that the underlying mechanism involves the viral NS3/4 protease and the cohesin regulator, WAPL (Mus musculus) PubMed

 24133.

NADPH: 2-ketopropyl-coenzyme M oxidoreductase/carboxylase (2-KPCC) is a bacterial disulfide oxidoreductase (DSOR) that, uniquely in this family, catalyzes CO2 fixation. The reduced, reactive form of 2-KPCC was distinct from those typical DSORs. In the absence of the histidine, the flavin and disulfide moieties were no longer coupled via a covalent or charge transfer interaction as in typical DSORs. [2-KPCC] (Mus musculus) PubMed

 24134.

This study performed an extended substrate screen and extensive biochemical characterization of the recombinantly expressed and purified phosphoglycolate phosphatase (PGP), leading to the identification of 2-phosphoglycolate and 2-phospho-L-lactate as the relevant physiological substrates of PbPGP. [phosphoglycolate phosphatase] (Mus musculus) PubMed

 24135.

these findings support a co-regulatory mechanism of BdALMT12 activation by malate, and Ca(2+)/CaM, emphasizing that a complex regulatory network modulates BdALMT12 activity. (Mus musculus) PubMed

 24136.

The data suggest that loss of MYPT1 recruitment (as a result of CT228 disruption) regulates the degree of host cell exit via extrusion and affects the longevity of infection in vivo (CT228). (Mus musculus) PubMed

 24137.

The authors show that FlgP interacts with FlgH and FlgT, indicating that FlgP should be localized closely to the L and H rings during flagella biogenesis.[FlgP] (Mus musculus) PubMed

 24138.

These findings indicate that NifZ has an equivalent, although not essential, function in the maturation of both P-clusters contained within the MoFe protein. (Mus musculus) PubMed

 24139.

The authors' study uncovers a novel function of HUB2 in plants in addition to its monoubiquitination of H2B. Moreover, they provide evidence for control of the fiber development by the ubiquitin-26S proteasome pathway. (Mus musculus) PubMed

 24140.

The authors conclude that FarR is needed to promote the expression of farE while strongly autorepressing its own expression.[FarR, farE] (Mus musculus) PubMed

 24141.

The presence of an A-tract extending downstream from the -35 element at OrbS-dependent promoters was shown to be an important contributor to Burkholderia cenocepacia OrbS specificity, but was not required for the binding of Pseudomonas aeruginosa PvdS.[OrbS] (Mus musculus) PubMed

 24142.

This study suggests that CsWOX1 may regulate early reproductive organ development and be involved in sporogenesis via the CsSPL-mediated pathway and/or modulate auxin signaling in cucumber.[SPL] (Mus musculus) PubMed

 24143.

loss of capping protein does not significantly affect the assembly of the dynactin Arp1 filament or the formation of the dynein-dynactin-C-HookA (Hook in A. nidulans) complex.[capA, dynein, Arp1] (Mus musculus) PubMed

 24144.

the role of a mutation in the POlarity Defective (podB) gene on growth, protein secretion, and cell wall organization in Aspergillus nidulans was studied using a temperature sensitive (Ts) mutant.[PodB] (Mus musculus) PubMed

 24145.

PHK1 and PHK2 delay the timing of gametophore development, probably by suppressing light-induced caulonema branching.[PHK1,PHK2] (Mus musculus) PubMed

 24146.

MYB108 (CA05g15480) is involved in the regulation of capsaicinoids biosynthesis and stamen development. [MYB108] (Mus musculus) PubMed

 24147.

findings suggest that, although not required for intracellular replication of L. pneumophila, RavD is a part of the molecular mechanism that steers the Legionella-containing vacuole away from endolysosomal maturation pathways. (Mus musculus) PubMed

 24148.

These results provide evidence for ATP4 proteins playing a key conserved role in Na(+) regulation in apicomplexan parasites. (Mus musculus) PubMed

 24149.

NanH2 and NanH3 are the primary sources of sialidase activity in G. vaginalis and that these two enzymes can account for the previously described substrate breadth cleaved by sialidases in human vaginal specimens of women with BV. (Mus musculus) PubMed

 24150.

The multifunctional nucleocapsid protein (N protein) plays a crucial role in the establishment of viral infection and is an important structural component of the virion. The N protein has a distant RNA-binding site in the stalk domain that specifically recognizes the vRNA panhandle, formed by the base pairing of complementary nucleotides at the 5' and 3' termini of the vRNA genome. [nucleocapsid protein] (Mus musculus) PubMed

 24151.

[ApcD and ApcF] The lack of ApcD and ApcF inhibits state transitions in Synechocystis but not in S. elongatus. In addition, lack of ApcF decreases energy transfer to both photosystems only in Synechocystis, while the lack of ApcD alters energy transfer to photosystem I only in S. elongatus. (Mus musculus) PubMed

 24152.

[ApcD and ApcF] The lack of ApcD and ApcF inhibits state transitions in Synechocystis but not in S. elongatus. In addition, lack of ApcF decreases energy transfer to both photosystems only in Synechocystis, while the lack of ApcD alters energy transfer to photosystem I only in S. elongatus. (Mus musculus) PubMed

 24153.

[CSE] Study describes a previously unreported Ca2+-binding protein which was called the Ca2+ Sensor EF-hand (CSE), which is conserved in filamentous, nitrogen-fixing cyanobacteria. CSE is shown to bind Ca2+, which induces a conformational change in the protein structure. Poor growth of a strain of Anabaena sp. PCC 7120 overexpressing CSE was attributed to diminished photosynthetic performance. (Mus musculus) PubMed

 24154.

Loss of ZmMs30 function resulted in defective anther cuticle, irregular foot layer of pollen exine, and complete male sterility. [ZmMs30] (Mus musculus) PubMed

 24155.

GhARF2 and GhARF18 genes may be key regulators of cotton seed fibre initiation by regulating the expression of several transcription factor genes.[ARF2,ARF18] (Mus musculus) PubMed

 24156.

Esterase Est3385 from Rhodopseudomonas palustris PSB-S was cloned and characterized. This enzyme could detoxify various pyrethroid pesticides; the optimal substrate is fenpropathrin. No cofactor was found to affect Est3385 activity but substantial reduction of enzymatic activity was observed when metal ions were applied. (Mus musculus) PubMed

 24157.

the K(+) ions stimulate the highest activity and strongest ligand binding of SAHase in comparison to other alkali cations, while the Zn(2+) ions inhibit the enzyme activity.[PaSAHase] (Mus musculus) PubMed

 24158.

Transient protonation of a universally conserved carboxylate on subunit c (D61 in E. coli) gated by the electrostatic interaction with arginine on subunit a (R210 in E. coli) is believed to be a crucial step in proton transfer across the membrane.[ATP synthase (H+)] (Mus musculus) PubMed

 24159.

the functional alterations reflect a mechanism that regulates O2 binding and trapping in CytcO, thereby altering energy conservation by the enzyme.[CytcO] (Mus musculus) PubMed

 24160.

GroEL/ES mediated the in vivo recovery of TRAIL inclusion bodies in Escherichia coli.[GroEL, GroES] (Mus musculus) PubMed

 24161.

This study provides evidence of a direct link between MoSnt2 and MoTor signaling and defines a novel epigenetic mechanism by which MoSNT2 regulates infection-associated autophagy and plant infection by the rice blast fungus.[MoSnt2, MoTor] (Mus musculus) PubMed

 24162.

S-acylation is essential for BSCTV C4 function, including the regulation of the CLAVATA pathway, during geminivirus infection.[C4 protein] (Mus musculus) PubMed

 24163.

The TaCBL4-TaCIPK5 complex positively modulates wheat resistance in a reactive oxygen species-dependent manner, and provide new insights into the roles of CBL-CIPK in wheat.[CBL4,CIPK5] (Mus musculus) PubMed

 24164.

6G&1-FEH may be involved in fructan hydrolysis in asparagus roots to provide an energy source for emerging asparagus spears.[6G&1-FEH] (Mus musculus) PubMed

 24165.

Taken together, these studies indicate that SodA is important for oxidative resistance and virulence of avian pathogenic Escherichia coli E058.[SodA] (Mus musculus) PubMed

 24166.

Constitutive expression of both icaR and tcaR demonstrated that both repressors are functional and can completely repress icaADBC transcription in both strain 1457 and strain CSF41498. However, it was found that IcaR was the primary repressor for CSF41498 and TcaR was the primary repressor for 1457.[icaR, tcaR] (Mus musculus) PubMed

 24167.

Because the HsdS subunit is responsible for the sequence specificity of type I restriction modification DNA methyltransferase, these results have revealed that Streptococcus pneumoniae varies the methylation patterns of the genome DNA (epigenetic status) by employing multiple mechanisms of DNA inversion in the cod locus.[HsdS] (Mus musculus) PubMed

 24168.

These assays revealed that SinK autophosphorylation and its REC1 domain impact the onset of aggregation and/or the mobility of aggregates, while the REC2 domain impacts sporulation efficiency.[SinK] (Mus musculus) PubMed

 24169.

[AhpCD (alkyl hydroperoxide reductase)] A. caulinodans AhpCD is not only important for H2O2 detoxification in vitro but also critical for symbiosis with Sesbania rostrata (Mus musculus) PubMed

 24170.

This study demonstrated that MDP1-deficiency and conditional knock out of MDP1 cause spreading of the M. smegmatis genome in the stationary phase. This study thus demonstrates for the first time a C-terminal region-dependent organization of the genome architecture by MDP1, implying the significance of intrinsically disordered regions in the function of bacterial histone-like protein. [MDP1] (Mus musculus) PubMed

 24171.

An intramolecular disulfide bond is formed between C229 and C307 in Sll1961 under oxidizing conditions and TrxM can reduce it by attacking C307.[ Sll1961, TrxM] (Mus musculus) PubMed

 24172.

SpaA dependent spore gene expression required PKA in vivo and was stimulated in vitro by the membrane-permeant PKA agonist 8Br-cAMP. The PKA agonist also promoted SpaA binding to (pre)spore promoters, placing SpaA downstream of PKA.[SpaA, PKA] (Mus musculus) PubMed

 24173.

These results suggest that Cin8 interactions with protein phosphatase 1 (PP1) plays a critical role at kinetochores to promote accurate chromosome segregation by controlling Ndc80 attachment to microtubules.[PP1] (Mus musculus) PubMed

 24174.

Multidrug-resistant Acinetobacter baumannii chloramphenicol resistance requires an inner membrane permease, ABUW_0982. [ABUW_0982]. (Mus musculus) PubMed

 24175.

TB/CYC (TEOSINTE-BRANCHED/CYCLOIDEA)-TCP1 & TCP2 are destabilized by phytoplasma SAP11 effectors, leading to the proliferation of axillary meristems.[SAP11] (Mus musculus) PubMed

 24176.

Study shows that PfRUVBL3 protein is a true homolog of yeast RUVBL2. PfRUVBL3 protein can also form similar high molecular weight oligomers of hexamer size. PfRUVBL3 possess DNA cleavage activity by which it can convert supercoiled dsDNA into linearized form. Also, MYST protein is identified as its interacting partner. [RUVBL3, MYST] (Mus musculus) PubMed

 24177.

The results suggest that BrLTP2.1 may function to prevent microbial growth in nectars (LTP2.1). (Mus musculus) PubMed

 24178.

after 12 weeks, the bone volume induced by co-delivery of BMP-2 and IL-17 was doubled as compared to that induced by BMP-2 alone...The use of IL-17 may contribute to the development of improved bone graft substitutes. (Mus musculus) PubMed

 24179.

The high-affinity interaction between A55BB and Cul3-NTD suggests that, in addition to directing the Cul3-RING E3 ligase complex to degrade cellular/viral target proteins that are normally unaffected, A55 may also sequester Cul3 from cellular adaptor proteins, thereby protecting substrates of these cellular adaptors from ubiquitylation and degradation. (Mus musculus) PubMed

 24180.

a structured domain in Atg32 that is essential for the initiation of mitophagy, was identified.[Atg32] (Mus musculus) PubMed

 24181.

finding suggests that there is a dynamic interplay between RRM2 and the NS5B-hPLIC1 complex that has an important function in HCV replication. Together, these results identify a role of host RRM2 in viral RNA replication. (Mus musculus) PubMed

 24182.

Biochemical analyses indicated that BmCDA8 is an active enzyme that requires its substrates to occupy subsites 0, +1, and +2 for catalysis. In contrast, BmCDA1 also required accessory proteins for catalysis. (Mus musculus) PubMed

 24183.

CsERF110 and CmERF110 respond to ethylene signaling, mediating ethylene-regulated transcription of CsACS11 and CmACS11 in cucumber and melon, respectively. Furthermore, the mechanism involved in its regulation is thought to be conserved in these two Cucumis species.[ACS11 and ERF110] (Mus musculus) PubMed

 24184.

GadR is a positive transcriptional regulator controlling gamma-aminobutyric acid conversion and acid resistance in L. brevis. [GadR ] (Mus musculus) PubMed

 24185.

OsCCD1 and OsCCD4a had a similar high carotenoid degrading activity, followed by OsCCD4b without substrate specificity. Overall, the results suggest that suppresing OsCCD4a activity may have potential as a tool for enhancing the carotenoid content of seed endosperms and leaves in rice.[CCD1,CCD4a] (Mus musculus) PubMed

 24186.

Cathepsin X was most abundant in the jejunum and protein levels were elevated in duodenum and colon of Ctsb-/- mice [CATHEPSIN X] (Mus musculus) PubMed

 24187.

clsp-1 protein. These results suggest that the CLSP-mediated attenuation of memory impairment and synaptic loss occurs in an Abeta-independent manner (Mus musculus) PubMed

 24188.

analysis of zebrafish Ccdc80 and Ccdc80-like1 (Ccdc80-l1) proteins; Ccdc80-l1 is involved in axon pathfinding of zebrafish motoneurons (Mus musculus) PubMed

 24189.

Caenorhabditis elegans yields a substance(s) inducing the larval diapause dauer-inducing pheromone (Mus musculus) PubMed

 24190.

The signaling cascade includes NO/cGMP/PKG and Ca(2+) influx through the Na(+)/Ca(2+) exchanger and might be related to the plasma membrane GLAST [GLAST] (Mus musculus) PubMed

 24191.

RERE activity is needed for proper neural progenitor proliferation and neuronal differentiation possibly by affecting Notch-mediated Hes expression [RERE] (Mus musculus) PubMed

 24192.

In 2-week-old conduit pulmonary artery, beside being a direct activator of soluble guanylate cyclase activator , YC-1 produced endothelium-dependent relaxation and synergized with exogenous nitric oxide. [soluble guanylate cyclase activator] (Mus musculus) PubMed

 24193.

we characterize a blaDIM-2-carrying 409 kb megaplasmid p12969-DIM of Pseudomonas putida 12969 from a patient with pneumonia in China [blaDIM-2] (Mus musculus) PubMed

 24194.

A carbapenem-resistant Escherichia coli isolate recovered from an Algerian patient expressed a novel VIM-type metallo-beta-lactamase, bla(VIM-19) [bla(VIM-19)] (Mus musculus) PubMed

 24195.

These findings indicate that the fosA3 gene may be coselected by antimicrobials other than fosfomycin [fosa3] (Mus musculus) PubMed

 24196.

Escherichia coli isolate resistant to all beta-lactams, including carbapenems, expressed a novel metallo-beta-lactamase (MBL), NDM-4, differing from NDM-1 by a single amino acid substitution [NDM4] (Mus musculus) PubMed

 24197.

In the biosynthetic pathway of the antibiotic thiostrepton A, we identified what is to our knowledge the first tryptophan methyltransferase [Thiostrepton tryptophan methyltransferase] (Mus musculus) PubMed

 24198.

coproduction of RmtE and CMY-2 along with other various resistance elements from a broad-host-range, self-conjugative plasmid suggests its potential for future spread [RMTE 16S RRNA METHYLTRANSFERASE] (Mus musculus) PubMed

 24199.

we report eight cases of Klebsiella pneumoniae with bla(NDM-1) in the neonatal ward of a teaching hospital in mainland China [NDM-1] (Mus musculus) PubMed

 24200.

GIsul2, a genomic island carrying the sul2 sulphonamide resistance gene and the small mobile element CR2 found in the Enterobacter cloacae Shigella flexneri ATCC 700930 [SUL2-] (Mus musculus) PubMed

 24201.

D-ribulose 5-phosphate 3-epimerase catalyzes the epimerization of D-ribulose 5-phosphate and D-xylulose 5-phosphate (Mus musculus) PubMed

 24202.

pERGB plasmid of Staphylococcus aureus was transferable by conjugation and carried the resistance gene ant(4')-Ia (tobramycin resistance) [ANT4'IA] (Mus musculus) PubMed

 24203.

A novel mutation in the vraS gene of Staphylococcus aureus contributes to reduce susceptibility against daptomycin [VRAS] (Mus musculus) PubMed

 24204.

The choline-binding protein CbpI was crystallized and X-ray crystallographic analysis showed that the crystals belonged to the tetragonal space group P4 [CbpI protein] (Mus musculus) PubMed

 24205.

the integrated form, tet(O) lies close to the right end of the prophage [TET(O)] (Mus musculus) PubMed

 24206.

ICESp1116, responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, was comprehensively characterized [erm(b)] (Mus musculus) PubMed

 24207.

Gene (devA) gene is required for proper development of Streptomyces coelicolor [DevA] (Mus musculus) PubMed

 24208.

we show that vanKHAX gene glucose is not required for teicoplanin resistance in S. coelicolor, which instead is mediated solely by vanJ [vanJ] (Mus musculus) PubMed

 24209.

the intracellular localization of Carboxypeptidase Y (CPY) inhibitor I(C)h was different from that of Carboxypeptidase Y (CPY) [Carboxypeptidase Y inhibitor (ICH)] (Mus musculus) PubMed

 24210.

Calsequestrin 2 (CSQ2) is generally regarded as the primary Ca2+-buffering molecule present inside the sarcoplasmic reticulum in cardiac cells (Mus musculus) PubMed

 24211.

the intracellular localization of Carboxypeptidase Y (CPY) inhibitor I(C)h was different from that of Carboxypeptidase Y (CPY) [Carboxypeptidase Y inhibitor (IC)] (Mus musculus) PubMed

 24212.

The gp37 gene was cloned into pMD18-T vector, and was sequenced. Then, pFast-BacHTb-gp37 vector was constructed and expressed by baculovirus expression vector system annd successfully expressed in sf9 cells. (Mus musculus) PubMed

 24213.

The leader proteinase (Lpro) of the foot-and-mouth disease virus inhibits the host innate immune response [LPRO] (Mus musculus) PubMed

 24214.

pMdT1 is the smallest mobilizable ColE1-like plasmid containing an aac(6')-Ib-cr gene that has been described so far [aac(6')-Ib-cr] (Mus musculus) PubMed

 24215.

Fks1-Fks2 redundancy attenuates the rate of resistance; further analysis showed that it also attenuates the impact of resistance-conferring mutations [FKS1] (Mus musculus) PubMed

 24216.

stromal myofibroblasts may be a major cellular source of tenascin-C and be involved in malignant progression of feline mammary tumor (Mus musculus) PubMed

 24217.

We present a crystal structure at 2.3-A resolution of the recently described nucleolytic ribozyme twister [ribozyme twister] (Mus musculus) PubMed

 24218.

Replacement of one of the endogenous UPC2 alleles in a fluconazole-susceptible strain by the UPC2(A643T) allele resulted in ERG11 overexpression [Upc2p] (Mus musculus) PubMed

 24219.

we investigated the association between in vitro quinine susceptibility and genetic polymorphisms in Pfmdr1, Pfcrt, and Pfnhe1 in 88 field isolates from western Kenya [PFNHE1] (Mus musculus) PubMed

 24220.

The raffinose-binding protein component of this system shares strong sequence homology with the multiple sugar metabolism substrate-binding protein from Streptococcus mutans. [RafE protein] (Mus musculus) PubMed

 24221.

there has been a significant increase in pilus prevalence, now exceeding rates from the pre-conjugate vaccine era in Massachusetts [Pneumococcal type 1 pilus] (Mus musculus) PubMed

 24222.

we performed fluorescent differential display screening and identified a novel gene, termed Fben-1 (Female-brain expressed noncoding RNA-1), whose expression is preferential to the female brain [FBEN1] (Mus musculus) PubMed

 24223.

a mutation induces a proline-to-arginine substitution in the homodimerization interface of pst1 system resulting in diminished sugar uptake [PST1] (Mus musculus) PubMed

 24224.

The dfrK gene encodes a 163-amino-acid dihydrofolate reductase that differs from all so-far-known dihydrofolate reductases [Dfrk] (Mus musculus) PubMed

 24225.

sfo-1 beta lactamase was cloned in the expression vector pBGS18 under the control of the CTX-M promoter and expressed in Escherichia coli MG1655 [sfo-1 beta lactamase] (Mus musculus) PubMed

 24226.

these findings indicate a plasticity of the OXA-48 genetic environment mediated by IS1 repressor insertion sequences [OXA-48] (Mus musculus) PubMed

 24227.

we determined the X-ray crystallographic structure of Mox-1 beta-lactamase [MOX1] (Mus musculus) PubMed

 24228.

Inactivation of mrcA, predicted to encode penicillin-binding protein 1a, causes basal L1/L2 beta-lactamase hyperproduction in S. maltophilia [BETA LACTAMASE L2] (Mus musculus) PubMed

 24229.

In this study, nagZ of Stenotrophomonas maltophilia was characterized, and its roles in basal-level beta-lactamase derepression [NagZ] (Mus musculus) PubMed

 24230.

SUL-1--Majority (58.3%) of sul1 gene positive were not associated with class 1 integrase gene (Mus musculus) PubMed

 24231.

qnra6 protein, proteus mirabilis--determines the genetic location and environment of the qnrA6 gene in Proteus mirabilis PS16 where it was first described and to characterize the quinolone resistance qnrA6 confers (Mus musculus) PubMed

 24232.

we identified prephenate dehydrogenases (TyrA(p)s, also known as PDHs) from Glycine max (soybean) [prehenate dehydrogenase] (Mus musculus) PubMed

 24233.

In the presence of recipient strains, the bla(CTX-M-9) resistance gene was transferred from a strain of animal origin to the human intestinal flora [CTX-M-9] (Mus musculus) PubMed

 24234.

the structural components of the AcrAB-TolC efflux pump appear to play a role in antibiotic resistance as well as environmental adaptation and host virulence in clinical isolates of Enterobacter cloacae [AcrAB-TolC] (Mus musculus) PubMed

 24235.

Future in vitro biosynthesis of Vi antigen may also be drug targets to inhibit Vi antigen production. [vi antigen] (Mus musculus) PubMed

 24236.

Our study, as a whole, provides new insights on VIH regulation of shrimp reproduction [vitellogenesis-inhibiting hormone (VIH)] (Mus musculus) PubMed

 24237.

eukaryotic elongation factor 2 (eEF2) is differentially regulated in separate compartments and contributes to a growing body of evidence that inhibition of elongation can stimulate the translation of certain transcripts (Mus musculus) PubMed

 24238.

The structure, homologies, polymorphism and expression profiles of a new gene, aap1, have been studied for precisely characterizing it and defining its putative involvement in vegetative mycelium growth and sporophore differentiation [aap1] (Mus musculus) PubMed

 24239.

thymus activity factor II is a new peptide isolated from calf thymus (Mus musculus) PubMed

 24240.

Adenovirus 5 exploits the cellular aggresome response to accelerate inactivation of MRE11-RAD50-NBS1 (MRN) complexes that otherwise inhibit viral DNA replication and packaging. [NBS1] (Mus musculus) PubMed

 24241.

To screen for antiviral IFN-stimulated genes that restricted Zika virus replication, and identified PARP12 as a strong inhibitor of Zika virus replication. Findings suggest that PARP12 mediated the ADP-ribosylation of NS1 and NS3, nonstructural viral proteins that are involved in viral replication and modulating host defense responses. [NS1, NS3] (Mus musculus) PubMed

 24242.

Results demonstrate that NS5A undergoes UBE2S-mediated proteasomal degradation pathway via Lys11-linked ubiquitin chains. [NS5A] (Mus musculus) PubMed

 24243.

Results found hemagglutinin (HA) mutations near and distal to the antibody binding epitope that conferred resistance to antibody neutralization. Also, a neuraminidase (NA) mutation was found allowing the virus to grow in the presence of high concentrations of the antibody. NA mutations seem to mediate the escape of neutralization by antibodies against HA. [HA, NA] (Mus musculus) PubMed

 24244.

This study revealed a duality of MAPK signaling pathway in the control of metabolic processes and cellulase expression, in which TMK2 seems to be more responsible controlling basal development of T. reesei, while TMK1 showed a specialist role in the regulation of cellulase expression in this fungus. [cellulase] (Mus musculus) PubMed

 24245.

There is a relationship between exploratory behavior and the expression of genes that have been previously linked with other behaviors in social insects. Specifically, there is a negative relationship between exploratory behavior and the expression of the foraging (Lhfor) gene.[for] (Mus musculus) PubMed

 24246.

PyPuf3 changed its localization from being nucleolar to being present in cytosolic puncta in the mosquito and liver stages.[Puf3] (Mus musculus) PubMed

 24247.

(Ugt2b) The clock gene, Rev-erbalpha, negatively regulates the expression of Ugt2b genes, contributing to their circadian variations. (Mus musculus) PubMed

 24248.

Bm-iAANAT3: Expression and characterization of a novel arylalkylamine N-acyltransferase from Bombyx mori. (Mus musculus) PubMed

 24249.

IP6K2 binds selectively to the neuronal protein 4.1N. Both are highly expressed in granule cells of the cerebellum. In IP6K2 knock-out mice, IP6K2-4.1N interactions in granule cells regulate Purkinje cell morphology, the viability of cerebellar neurons, and psychomotor behavior. 4.1N (Mus musculus) PubMed

 24250.

The study found that the frequent appearance of P. aeruginosa mexZ mutants in cystic fibrosis patients is directly connected to the intense use of the target antibiotics, and low-level antibiotic resistance, if left unnoticed, can result in accumulation of additional genetic changes leading to high-level resistance. [mexZ] (Mus musculus) PubMed

 24251.

expression control of Ptp2 and Cmp2 protein phosphatases at the promoter level is crucial for adaptive responses to endoplasmic reticulum stress.[Ptp2, Cmp2] (Mus musculus) PubMed

 24252.

Our results show that CK11 a CC chemokine, strongly inhibits the growth of different rainbow trout Gram-positive and Gram-negative bacteria [CK11]. (Mus musculus) PubMed

 24253.

Our study builds a structural framework for understanding of NleB-catalyzed arginine GlcNAcylation of host death domain. (Mus musculus) PubMed

 24254.

the surface-associated 5'-nucleotidase S5nA seems dispensable for evasion of phagocytosis and biofilm formation in S. pyogenes. (Mus musculus) PubMed

 24255.

Gp35/50 kDa mucins, the major surface glycoproteins from T. cruzi insect-dwelling forms, are involved in parasite attachment to the internal cuticle of the triatomine rectal ampoule, a critical step leading to its differentiation into mammal-infective forms.[Gp35/50 mucins, encoded fromTcSMUG S gene ] (Mus musculus) PubMed

 24256.

Study data demonstrate that Staphylococcus aureus cell wall metabolism sensor histidine kinase WalK/VicK cytoplasmic PAS domain is an intracellular sensor that potentiates the WalR/VicR regulon via interaction with Zn2+ ions.[sensory box histidine kinase WalK/VicK, Staphylococcus aureus USA300_NRS384] (Mus musculus) PubMed

 24257.

NnaR was the key regulator of the expression of the truncated haemoglobin trHbN, which is required to improve the survival of bacteria under nitrosative stress. (Mus musculus) PubMed

 24258.

Genome-wide analysis of the FleQ direct regulon in Pseudomonas fluorescens F113 and Pseudomonas putida KT2440 has been reported. [FleQ] (Mus musculus) PubMed

 24259.

Here, the authors show that a qcrABC deletion mutant is completely deficient in oxygen-limited growth on both nitrate and TMAO and is unable to reduce these oxidants with physiological electron donors.[qcrABC] (Mus musculus) PubMed

 24260.

Taken together, our study provides a mechanism explaining how FliW and FliS synchronize the production of flagellin with the capacity of the flagellar type III secretion system to secrete flagellin.[FliS, FliW, flagellin] (Mus musculus) PubMed

 24261.

Salmon isavirus NP triggers a strong production of ROS and modifying the post-translational profile mediated by SUMO-2/3, a phenomenon that favors the production of new virions. [NP] (Mus musculus) PubMed

 24262.

Tp0136 interaction with host fibronectin receptor plays an important role in spirochetal attachment to mammalian cells. [Tp0136] (Mus musculus) PubMed

 24263.

The assembly of SafA thus involves sequential protein-protein and protein-peptidoglycan interactions, mediated by the LysM domain, which are required first for encasement then for the final localization of the protein in mature spores.[SafA] (Mus musculus) PubMed

 24264.

In primary striatal cultures, transcription of Dnmt3a2, not Dnmt3a1, is activated by dopamine D1 receptor signaling. Knockdown of Dnmt3a2 using viral vector-mediated expression of Dnmt3a2-specific shRNAs impairs induction of the IEGs, Arc, FosB, and Egr2. Dnmt3a2. (Mus musculus) PubMed

 24265.

P230p, like P230 and P48/45, has a vital role in P. falciparum male fertility and zygote formation. (Mus musculus) PubMed

 24266.

The membrane-embedded quinol:fumarate reductase (QFR) in anaerobic bacteria catalyzes the reduction of fumarate to succinate by quinol in the anaerobic respiratory chain. This study reports the crystal structure of QFR from the anaerobic sulphate-reducing bacterium Desulfovibrio gigas at 3.6 A resolution. [quinol:fumarate reductase ] (Mus musculus) PubMed

 24267.

The protein Asa was verified by Western blot. Close homologues of asa have not been found in protein databases, but bioinformatic analyses showed that it may be membrane associated, having a largely disordered structure.[Asa] (Mus musculus) PubMed

 24268.

Expression and function of lnc-C/EBPbeta in the myeloid-derived suppressor cells,[lnc-C/EBPbeta] (Mus musculus) PubMed

 24269.

The structure of the complex of PPAT with citric acid showed that its structure is similar to that from various other bacterial species. It showed that trisodium citrate bound to PPAT at the ATP binding site and formed several intermolecular contacts including 12 hydrogen bonds. [PPAT] (Mus musculus) PubMed

 24270.

The absence of yjbH or yjbI resulted in altered sensitivities to nitrosative and oxidative stress and iron deprivation. [ yjbH ] (Mus musculus) PubMed

 24271.

Phenotypic assays showed that BmoR is important to maintain the thiol/disulfide balance in the cell, confirming its relevance to B. fragilis response to oxidative stress. (Mus musculus) PubMed

 24272.

DacA and Pde2 were critical to the production of the virulence factor SpeB and to the overall virulence of S. pyogenes. [SpeB] (Mus musculus) PubMed

 24273.

Study reports that the NS1 protein of influenza A virus (IAV) participates in necroptosis by interacting with MLKL, resulting in increased MLKL oligomerization and membrane translocation. These results reveal a novel function of the NS1 protein and the mechanism by which IAV induces necroptosis. [NS1] (Mus musculus) PubMed

 24274.

The gene expression analyses in Morus notabilis floral bud indicated that MADS-box gene-33 (MnMADS33) expression increased, while FLOWERING LOCUS T-like (MnFT) expression decreased during the induction of dormancy in response to cold conditions. Dormancy release resulted in the down-regulation of MnMADS33 expression and the up-regulation of MnFT expression. [MnMADS33] (Mus musculus) PubMed

 24275.

The present study showed that inactivation of phosphorylation at the D53 residue of CovR contributes dominantly in suppressing rgg and speB transcription.[CovR, rgg, speB] (Mus musculus) PubMed

 24276.

The results of this study suggest that the main function of SfnR2 is to direct the initial activation of the msuEDC-sfnR1 operon in response to sulfur limitation or nonpreferred sulfur sources.[SfnR2] (Mus musculus) PubMed

 24277.

These results suggest TRSP may have a redundant role in the completion of the pre-erythrocytic phase of the malaria parasite.[TRSP] (Mus musculus) PubMed

 24278.

According to these results, SlyA represses rcsB transcription by direct binding to specific sites located on the rcsB promoters, thus accounting for the attenuated/virulence antagonistic behaviors.[SlyB, rcsB] (Mus musculus) PubMed

 24279.

In this study, the authors have determined the crystal structure of the potent membrane attack complex inhibitor BGA71 at 2.9 A resolution. The structure revealed a cysteine cross-linked homodimer.[BGA71] (Mus musculus) PubMed

 24280.

Leu4 and Asn12 of CSP are important for effective SepM recognition and processing. [SepM] (Mus musculus) PubMed

 24281.

elevated eEF1A abundance can partially compensate for functional defects induced by loss of tRNA modifications.[eEF1A] (Mus musculus) PubMed

 24282.

This study demonstrated that ribokinase had good potential for the serodiagnosis of tuberculosis [ribokinase]. (Mus musculus) PubMed

 24283.

Surveillance of Antimalarial Resistance Pfcrt, Pfmdr1, and Pfkelch13 Polymorphisms in African Plasmodium falciparum imported to Shandong Province, China. (Mus musculus) PubMed

 24284.

The cacao pathogen Moniliophthora perniciosa evolved an enzymatically inactive chitinase (MpChi) that functions as a putative pathogenicity factor.[Chi] (Mus musculus) PubMed

 24285.

PbsP is required for brain invasion by hypervirulent CC17 Group B streptococci [PbsP] (Mus musculus) PubMed

 24286.

Study provides evidence that HamE acts as a positive regulator of MpkB phosphorylation, allowing for HamE to subsequently regulate development and secondary metabolism in aspergillus nidulans. [HamE] (Mus musculus) PubMed

 24287.

The results collectively indicated that Lc-TRIF was function in host antiviral and antibacterial responses via NF-kappaB and IRF3/7 related signaling pathway.[TRIF] (Mus musculus) PubMed

 24288.

NBL could be important for X chromosome dosage compensation in L. cuprina. NBL may also facilitate gene expression in the heterochromatic environment of the X chromosome in both sexes.[NBL] (Mus musculus) PubMed

 24289.

Study reported for the first time that the G-rich region in the EP0 promoter of pseudorabies virus (PRV) formed a parallel G4 structure, and the G4 facilitated the binding of Sp1 to the EP0 promoter. [EPO] (Mus musculus) PubMed

 24290.

results suggest a role for LptC in achieving efficient lipopolysaccharide transport, by coordinating the action of LptB2FG in the inner membrane and Lpt protein interactions in the periplasm [lptC] (Mus musculus) PubMed

 24291.

Sox6 is verified as a direct target of miR-135a-5p. miR-135a-5p is critical for efficient neuronal differentiation. [miR-135a-5p] (Mus musculus) PubMed

 24292.

Study in influenza A virus (IAV) and Streptococcus pyogenes (GAS) model of viral-bacterial superinfection revealed that Streptococcus pyogenes PrtF.2 contributes to virulence in a murine model of IAV-GAS superinfection.[PrtF.2;Protein F2] (Mus musculus) PubMed

 24293.

We also observed a reduction in NS5A cluster size following inhibition of RNA replication using daclatasvir, a phenotype which was maintained in the presence of the Y93H resistance associated substitution and not observed for NS3 clusters. These results provide insight into the NS protein organisation within hepatitis C virus RNA replication complexes and the mode of action of NS5A inhibitors. (Mus musculus) PubMed

 24294.

HCV core fragment (Core71) binds to the 20S proteasome and its activator PA28gamma. The N-terminal 1-71 fragment of Hepatitis C virus (HCV) core protein (Core71) enhances the PA28gamma-20S complex formation with reduced proteolytic activity. Fragmented HCV core can cause pathogenic dysfunction of proteasomes in the nucleus. [core protein] (Mus musculus) PubMed

 24295.

CagIFNa transcripts were detected in all investigated tissues with higher levels in the liver, intestine, spleen and head kidney of gibel carp. Following injection with Cyprinid herpesvirus 2 (CyHV-2), CagIFNa gene expression was significantly inhibited in the spleen but delayed and then increased in head kidneys.[IFNalpha] (Mus musculus) PubMed

 24296.

N-terminal residues are crucial for quaternary structure and active site conformation for the phosphoserine aminotransferase [phosphoserine amino transferase] (Mus musculus) PubMed

 24297.

The monomers of 3C-like cysteine protease are comprised of N-terminal domains I and II, which adopt a chymotrypsin-like fold, and a C-terminal alpha-helical domain III. [3C] (Mus musculus) PubMed

 24298.

EIAV NCp11 is thermostable. Upon heat treatment, NCp11 maintained its nonspecific RNA and the EIAVpsi-binding activities, maintained its inhibition of the first-strand cDNA synthesis at a very high degree of sequence occupancy (NCp11). (Mus musculus) PubMed

 24299.

although CCA1 genes have been found in many plant species, alternative CCA1 splicing events are known to occur in species-specific ways (Mus musculus) PubMed

 24300.

These results suggest that thioredoxin reductase (TrxR) responds to O2 and protects Bifidobacterium bifidum from oxidative stress by degrading H2O2 via the TrxR-alkyl hydroperoxide reductase (AhpC) system.[TrxR, AhpC] (Mus musculus) PubMed

 24301.

The crystal structure of archaeal msed_0281, the citrate synthase from Metallosphaera sedula was determined at 1.8A resolution. [citrate synthase] (Mus musculus) PubMed

 24302.

The x-ray crystal structure of EaFAH, a dimeric fumarylacetoacetate hydrolase from Exiguobacterium antarcticum, was determined. [fumarylacetoacetate hydrolase] (Mus musculus) PubMed

 24303.

BamB makes intimate contacts with BamA and BamB in neighboring BAM complexes within the precinct.[BamB] (Mus musculus) PubMed

 24304.

NS2B an NS3 proteases Study describes a role for the ZIKV protease NS2B-NS3 heterodimer in mediating neurotoxicity through cleavage of a host protein required for neurogenesis. NS2B-NS3 heterodimer cleaved Septin-2, a cytoskeletal factor involved in cytokinesis, leading to cytokinesis defects and cell death. (Mus musculus) PubMed

 24305.

The crystal structure of ZitR holo-form (Zn(II)4-ZitR2), has been determined at 2.8 A resolution. ZitR is the fourth member of the zinc-responsive repressor of the MarR metallo-regulator subgroup whose structure has been determined. [ZitR] (Mus musculus) PubMed

 24306.

One hydrogen bond was found between P03 and ArsS, which is more cohesive than other forms of bonding. (Mus musculus) PubMed

 24307.

eat-2(lf) mutants displayed a similar phenotype, indicating accumulation of live bacteria also triggers extended longevity in this mutant. The analysis of phm-2 elucidates connections between pathogen response and aging by defining a mechanism of longevity extension in C. elegans-bacterial colonization, innate immune activation, and bacterial avoidance behavior. (Mus musculus) PubMed

 24308.

BpNagZ was a thermostable enzyme with high activity in industrial application [beta-N-acetylglucosaminidase] (Mus musculus) PubMed

 24309.

Tet38 contributes to S. aureus invasion of A549 via direct binding to CD36 of the complex CD36-TLR-2.[Tet38] (Mus musculus) PubMed

 24310.

The production of p40, an Lactobacillus rhamnosus GG-derived secretory protein that protects intestinal epithelial cells against inflammation.[p40] (Mus musculus) PubMed

 24311.

glucoregulatory actions of metformin are mediated in part by a lncRNA, Dreh, in the skeletal muscle cells[lncRNA Dreh] (Mus musculus) PubMed

 24312.

The binding of filamin A by the RtxA11491-1971 domain appears to be a requisite to pak1-mediated MAPK activation, which contributes to the cytoskeletal reorganization and host cell death. [RtxA1] (Mus musculus) PubMed

 24313.

Base-paring plays an important role for the repression of metE(+) gene expression by FnrS. [ FnrS] (Mus musculus) PubMed

 24314.

Transcriptome analysis demonstrated that dextran production is related to the upregulation of the L. mesenteroides dextransucrase-encoding genes dsrD and dsrT during the first 4 to 8 h of exposure to high CO2 levels compared to aerated conditions.[dsrD;dsrT] (Mus musculus) PubMed

 24315.

The presence of SecYEG-bound FtsY and the length of the nascent chain strongly influence nascent-chain transfer from SRP to the translocon and repositioning of SRP in the post-transfer complex. (FtsY protein) (Mus musculus) PubMed

 24316.

A novel cry52Ca1 gene from an Indian Bt isolate was cloned and expressed in E. coli. (Mus musculus) PubMed

 24317.

We report that a novel aldehyde reductase Ykl107wp deduced from YKL107W from S. cerevisiae belongs to the classical short-chain dehydrogenase/reductase group and can catalyze the reduction reactions of acetaldehyde, glycolaldehyde, furfural, formaldehyde, and propionaldehyde [Ykl107wp]. (Mus musculus) PubMed

 24318.

These data strongly suggest that FgMed1 involved in regulation of genes associated with early conidiogenesis, DON production, and virulence in F. graminearum. (Mus musculus) PubMed

 24319.

Deletion of the CDC55 gene, encoding B55delta, abolished the high fermentation performance of Rim15p-deficient laboratory yeast and sake yeast cells, indicating that PP2A(B55delta) mediates the fermentation control by TORC1 and Rim15p. [CDC55] (Mus musculus) PubMed

 24320.

This chapter describes methods, including purification of recombinant SdeA (full-length and DUB domain alone), and enzymatic assays that have been utilized to characterize the deubiquitination activity of SdeA. [SdeA] (Mus musculus) PubMed

 24321.

Selective delivery of KLF2 to the carotid body reduces chemoreflex sensitivity, resting renal sympathetic nerve activity, disordered breathing and arrhythmia incidence, and improves cardiac autonomic function in a rapid-ventricular pacing model of chronic heart failure in rabbits [KLF2] (Mus musculus) PubMed

 24322.

We identified a gene coding for a novel protein of the TetR family (LcpRBA3(2)) downstream of lcpA3(2) and demonstrated its binding upstream of lcpA3(2). This indicates a role of LcpRBA3(2) in the regulation of lcp expression [LcpRBA3(2)]. (Mus musculus) PubMed

 24323.

YwqL (EndoV), ExoA and PolA act in a novel alternative excision pathway to repair deaminated DNA bases - [YwqL (EndoV)] (Mus musculus) PubMed

 24324.

A new Bt toxin (Cry78Aa) which shows high toxicity against rice planthopper. (Mus musculus) PubMed

 24325.

identification of 5,10-methylenetetrahydrofolate dehydrogenase amino acid residues that are likely to play roles in catalysis.(5,10-methylenetetrahydrofolate dehydrogenase). (Mus musculus) PubMed

 24326.

This chapter describes single-molecule fluorescence resonance energy transfer experiments carried out to investigate the Cas9 endonuclease from Streptococcus pyogenes, providing information on the effects of target truncation, Cas9-induced double-stranded DNA dynamics, and target search. [Cas9 endonuclease] (Mus musculus) PubMed

 24327.

Molecular characterization reveals that a single-base deletion results in a frame-shift mutation from the second chromodomain of Rice OsCHR4 Gene, a CHD3 (chromodomain helicase DNA-binding) family chromatin remodeler, in the Oschr4-5 mutant. OsCHR4 regulates leaf morphogenesis and cuticle wax formation by epigenetic modulation of auxin and wax biosynthetic genes expression. [chromodomain helicase DNA binding protein 3] (Mus musculus) PubMed

 24328.

Impact of tetramerization on the ligand recognition of N1 influenza neuraminidase via MMGBSA approach. (Mus musculus) PubMed

 24329.

miR-27b directly targets AMPK and inhibits AMPK expression. In cultured neural stem cells, miR-27b inhibitor improved proliferation and differentiation via the AMPK signaling pathway, but did not have an obvious effect on cell viability under oxygen and glucose deprivation conditions.[miR-27b] (Mus musculus) PubMed

 24330.

Findings demonstrate that proper regulation of emrR-emrAB is required for free-living A. tumefaciens to survive in deleterious environments in which toxic compounds are present [emrR]. (Mus musculus) PubMed

 24331.

Results suggest that enhanced expression of FoxO disturbs glycolipid metabolism and affects silkworm growth (FoxO). (Mus musculus) PubMed

 24332.

the viral protein NS5A forms a trimeric complex with IP3R3 and FBXL2, unmasking IP3R3's degron in the absence of inositol 1,4,5-trisphosphate (IP3) stimulation.[NS5A] (Mus musculus) PubMed

 24333.

The transcription factor Fil1 is required for ecl1 + induction by leucine depletion (Fil1). (Mus musculus) PubMed

 24334.

Molecular cloning, gene expression analysis, and in silico characterization of UDP-N-acetylglucosamine pyrophosphorylase from Bombyx mori [UAP] (Mus musculus) PubMed

 24335.

Results describe the 1.6A resolution crystal structure of beta-lactamase SHV-1.Beta-lactamase inhibitor protein (BLIP). (Mus musculus) PubMed

 24336.

clavulanic acid dehydrogenase is dimeric & tetrameric in solution; crystal structure shows that individual monomers comprise a single domain possessing Rossmann fold, characteristic of dinucleotide-binding enzymes[clavulanic acid dehydrogenase] (Mus musculus) PubMed

 24337.

clavulanic acid and cephamycin C production increased markedly in the relA mutants compared to the wild-type strain.[relA] (Mus musculus) PubMed

 24338.

Sources of structural plasticity appear to contribute to the promiscuity of the reaction between beta-lactamase inhibitor protein (BLIP) and Klebsiella pneumoniae beta-lactamase, which have been characterized crystallographically. (Mus musculus) PubMed

 24339.

the effect of S. coelicolor glcP1 (for glucose transport) and glkA (encoding the glucose kinase) genes on glucose utilization by S. clavuligerus [glcP1] (Mus musculus) PubMed

 24340.

AdpA is part of a regulatory cascade that controls clavulanic acid formation. [AdpA] (Mus musculus) PubMed

 24341.

The growth, cephamycin C and clavulanic acid production were impaired in the rhlA deletion mutants. [rhlA, rhodanese-like protein] (Mus musculus) PubMed

 24342.

ClaR regulated development and additional clusters for secondary metabolites. [ClaR] (Mus musculus) PubMed

 24343.

The oppa2 gene encodes an oligopeptide permease essential for the production of clavulanic acid.[oppa2] (Mus musculus) PubMed

 24344.

[noeM] A noeM deletion mutant of C. taiwanensis was affected for the nodulation of M. pudica, confirming the role of noeM in the symbiosis with this legume (Mus musculus) PubMed

 24345.

C1orf54 was found to promote tubular epithelial cells proliferation through PI3K/AKT signalling. Thus, C1orf54 holds considerable potential as a therapeutic target in kidney IRI (Mus musculus) PubMed

 24346.

structures of protein F9 and protein L1, two components of the conserved poxvirus entry-fusion complex. (Mus musculus) PubMed

 24347.

E. coli incorporates extracellular ADP-glucose through a cAMP/CRP-regulated process involving the NupC and NupG nucleoside transporters that is facilitated under envelope stress conditions.[NupC, NupG] (Mus musculus) PubMed

 24348.

This communication presents phylogenetic and biochemical evidence that AmyC is a glycogen-branching enzyme with a relatively high hydrolytic (alpha-amylase) activity (up to 30% of the total activity), creating a branched alpha-glucan with 8.5% alpha-1,6-glycosidic bonds.[AmyC] (Mus musculus) PubMed

 24349.

CsrA can promote the base-pairing interactions between SR1 and ahrC mRNA.[CsrA] (Mus musculus) PubMed

 24350.

MiR-204-3p and knockdown of lncRNA AK139328 relieved hypoxia/reoxygenation injury via inhibiting cardiomyocyte autophagy. Silencing lncRNA AK139328 significantly increased miR-204-3p expression and inhibited cardiomyocyte autophagy, thereby attenuating myocardial ischaemia/reperfusion injury (MIRI) in diabetic mice (DM). (Mus musculus) PubMed

 24351.

a large collection of messenger ribonucleoprotein whose biogenesis is affected by Rho action and which can be rescued upon Rrp6 depletion, were examined.[Rrp6] (Mus musculus) PubMed

 24352.

These results suggested that DRL1 plays a role as a negative regulator of leaf senescence by regulating ABA synthesis. [DRL1] (Mus musculus) PubMed

 24353.

Altogether, these results demonstrated the necessity of Hrip2 in suppression of host immunity and the full virulence of Magnaporthe oryzae.[Hrip2] (Mus musculus) PubMed

 24354.

The expression of genes in the cluster was significantly reduced in lcsL disruption mutants, and the output of leucinostatins was decreased to undetectable levels. In the lcsL overexpression strain, the expression of genes in the cluster and the yield of leucinostatins were all increased.[lcsL] (Mus musculus) PubMed

 24355.

CsGPA1 is a peptide of 392 amino acids with a predicted molecular mass of 44.6 kDa. Further study showed that CsGPA1 controled hypocotyl elongation and root growth via promoting cell size and the meristem of hypocotyl and root tip cells of cucumber plants.[CsGPA1] (Mus musculus) PubMed

 24356.

The phosphorylation deficient dephospho-CdtR-Asp61Ala was completely non-functional and mirrored the cdtR-deletion mutant, whilst phospho-CdtR-Asp61Glu was functional, possessing 38-52% of wild-type activity.[CtdR] (Mus musculus) PubMed

 24357.

These results demonstrate a structure-dependent mode of mRNA target recognition by a conserved pseudouridine synthase (pseudouridine synthase 1; PUS1) and implicate modulation of RNA structure as the probable mechanism to regulate mRNA pseudouridylation. [PUS1] (Mus musculus) PubMed

 24358.

Structural basis for RNA translocation by DEAH-box ATPase/helicase Prp22 has been revealed. [Prp22] (Mus musculus) PubMed

 24359.

Molecular modeling indicates that CRAM-1, through this UBA-like domain, can form tight complexes with mono- and di-ubiquitin and may thus prevent tagged proteins from interacting with adaptor/shuttle proteins required for degradation. [CRAM-1] (Mus musculus) PubMed

 24360.

The ATPase mechanism of UvrA dimers reveals the distinct roles of proximal and distal ATPase sites in nucleotide excision repair. [UvrA] (Mus musculus) PubMed

 24361.

Norovirus GII.4 Protease structure and active site description.[Norovirus GII.4 Protease] (Mus musculus) PubMed

 24362.

The majority of the mecI-positive methicillin-resistant Staphylococcus aureus strains contained the C to T substitution at position 202. [mecI] (Mus musculus) PubMed

 24363.

these observations lead to the conclusion that increased levels of intracytosolic Manganese(2+) activate TRPY1 in the response to oxidative stress.[TRPY1] (Mus musculus) PubMed

 24364.

data indicate a mechanism of Cenp-A nucleosome recognition by constitutive centromere associated network (CCAN) complex, and how CCAN acts as a platform for assembly of the outer kinetochore to link centromeres to the mitotic spindle for chromosome segregation [cenp-A] (Mus musculus) PubMed

 24365.

ATG12 and ATG16 fulfil autophagy-independent functions in addition to their role in canonical autophagy.[ATG12] (Mus musculus) PubMed

 24366.

On the overall, this correlation analysis reflected data from previous studies on other species highlighting how the abundance of transcripts encoding for CslF6 and CslH enzymes were not necessarily a good indicator of enzyme activity and/or beta- glucan deposition in cell wall. [CslF6, CslH ] (Mus musculus) PubMed

 24367.

Cwh43 affects utilization of glucose and nitrogen sources, as well as storage lipid metabolism. These results may fit a notion developed in budding yeast stating that Cwh43 conjugates ceramide to glycosylphosphatidylinositol (GPI)-anchored proteins and maintains integrity of membrane organization. [Cwh43 protein, S. pombe] (Mus musculus) PubMed

 24368.

This study determined the overall structure of Enterococcus hirae V-ATPase by single-particle Zernike phase plate cryo-electron microscopy. [V-ATPase] (Mus musculus) PubMed

 24369.

The roles of Ser-36, Asp-132 and Asp-201 in the reaction of Pseudomonas fluorescens Kynureninase. (Mus musculus) PubMed

 24370.

Results demonstrate that the OmpA C-terminal domain-mediated association to peptidoglycan is critical for a number of virulent properties displayed by A. baumannii outside and within the host. [OmpA] (Mus musculus) PubMed

 24371.

Study highlights recent findings of how regulated DnaA synthesis and degradation collaborate to adjust DnaA abundance under stress conditions. [DnaA] [review] (Mus musculus) PubMed

 24372.

These results indicated that BbApoA-I performed a protective function against bacterial infection in amphioxus. (Mus musculus) PubMed

 24373.

Virulence studies of Yersinia pestis strains mutated in individual twin-arginine translocation system components clearly indicated that the twin-arginine translocation system is central in Yersinia pestis pathogenicity and substantiated the assumption that NlpD essentiality in iron utilization involves the activity of the twin-arginine translocation system.[NlpD] (Mus musculus) PubMed

 24374.

From Circular Dichroism (CD) studies, we also show that MsGre has a stable secondary structure under thermal stress. We propose that the presence of C-terminal FKBP-like fold in MsGre factor that might contribute to its chaperone-like function. (Mus musculus) PubMed

 24375.

Glucitol dehydrogenase structure and cofactor specificity. [Glucitol Dehydrogenase] (Mus musculus) PubMed

 24376.

MftC binds a radical S-adenosylmethionine [4Fe-4S] cluster and two auxiliary [4Fe-4S] clusters that are required for MftA modification. [MftC] (Mus musculus) PubMed

 24377.

The authors observe that Aedes miR-2944b-5p binds to the 3' untranslated region of Chikungunya virus and the binding is abated when the binding sites are abolished. Furthermore, the study has shown miR-2944b-5p to be playing role, where one of its target vps-13 also contributes, in maintaining mitochondrial membrane potential in Aedes aegypti.[miR-2944b-5p, vps-13] (Mus musculus) PubMed

 24378.

Increased resistance to carbapenems has been reported in Proteus mirabilis mediated by amplification of the blaVIM-1-carrying and IS26-associated class 1 integron. [VIM-1] (Mus musculus) PubMed

 24379.

The mechanism of the H2O2 disproportionation catalyzed by the manganese catalase KatB was studied using the hybrid density functional theory B3LYP and the quantum chemical cluster approach. In the reaction pathway suggested for KatB using the Large chemical model, the O-O homolysis of the first substrate H2O2 occurs through a mu-eta(1):eta(1) coordination mode and requires a barrier of 10.9 kcal/mol. [KatB] (Mus musculus) PubMed

 24380.

Dictyostelium NE81 is also capable of assembling into filaments, just as metazoan lamin filament assemblies.[NE81] (Mus musculus) PubMed

 24381.

The gene BTA1, is highly up-regulated during phosphate starvation. BTA1 encodes a functional DGTS synthase. [DGTS synthase] (Mus musculus) PubMed

 24382.

circHIPK3 could promote the chicken embryonic skeletal muscle development by sponging miR-30a-3p.[circHIPK3] (Mus musculus) PubMed

 24383.

a latency-associated gene product (LUNA) promotes the disruption of cellular PML bodies during latency.[LUNA] (Mus musculus) PubMed

 24384.

investigated the binding capacity of the two atypical Dps proteins NpDps4 and NpDps5 from Nostoc punctiforme to isolated ferredoxins. (Mus musculus) PubMed

 24385.

investigated the binding capacity of the two atypical Dps proteins NpDps4 and NpDps5 from Nostoc punctiforme to isolated ferredoxins. (Mus musculus) PubMed

 24386.

degradosome-related enzymes polynucleotide phosphorylase (PNPase), ATP-dependent RNA helicase (RhlE), ribonuclease E (RNase E) and ribonuclease J (RNase J) are major components of the RNA degradosome complexes in the transcriptome of Mycobacterium tuberculosis [PNPase] (Mus musculus) PubMed

 24387.

The authors propose that engagement of AP-1A/3A by the cargo sorting motif in Murine cytomegalovirus m06 routes the m06-MHC-I complexes into the endosomal pathway and thereby detracts them from the constitutive cell surface transport.[m06] (Mus musculus) PubMed

 24388.

The PicC was Zn(2+)-dependent nonoxidative decarboxylase that can specifically catalyze the irreversible decarboxylation of 3,6-dihydroxypicolinic acid to 2,5-dihydroxypyridine.[PicC] (Mus musculus) PubMed

 24389.

miR-16-5p could inhibit myoblast proliferation, promote myoblast apoptosis, and repress myoblast differentiation by directly binding to the 3' UTR of SESN1. [miR-16-5p] (Mus musculus) PubMed

 24390.

In Xenopus extracts, PLK4 assemblies additionally recruit STIL[PLK4] (Mus musculus) PubMed

 24391.

targeting of the Jumonji demethylases JMJD-2 and JMJD-3/UTX-1 restores H3K9me3 and H3K27me3 levels, respectively, and it fully alleviates the bisphenol A-induced transgenerational effects.[utx-1] (Mus musculus) PubMed

 24392.

WAGO-4, necessary for the inheritance of RNA interference, was identified.[WAGO-4] (Mus musculus) PubMed

 24393.

HBZ-mediated activation of HMOX-1 expression may facilitate transformation. Overall, this study characterizes a novel function of HBZ that may support the development and maintenance of ATL. (Mus musculus) PubMed

 24394.

RpaA, is sufficient to generate complex circadian expression patterns in part by regulating an interdependent sigma factor cascade.[RpaA, Sigma factor] (Mus musculus) PubMed

 24395.

findings unveil a critical pathophysiological function for EspF during Citrobacter rodentium infection in the immunocompromised host and provide new insights into the complex pathogenic mechanisms of A/E pathogens. (Mus musculus) PubMed

 24396.

the G1 cyclin-dependent kinase CRK1 phosphorylates two translation initiation factors, eIF4E4 and PABP1, to promote the G1/S cell-cycle transition and global protein translation.[eIF4E4, PABP1] (Mus musculus) PubMed

 24397.

Metacaspase-2 (MC-2) expression and role in the plant immunity and defence against infection of Plasmopara viticola.[Metacaspase-2] (Mus musculus) PubMed

 24398.

DEK42 participates in the regulation of pre-messenger RNA splicing through its interaction with other spliceosome components.[Dek42] (Mus musculus) PubMed

 24399.

HDA6-GFP was expressed in the whole root and localized at the nucleus in Arabidopsis, rice, and cassava. Remarkably, HDA6-GFP clearly formed speckles that were actively colocalized with chromocenters in Arabidopsis root meristem. In contrast, such speckles were unlikely to be formed in rice or cassava.[HDA6] (Mus musculus) PubMed

 24400.

analysis of structure of Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4 [EIF4E5] (Mus musculus) PubMed

 24401.

Clostridium butyricum Argonaute has a role in DNA-guided DNA cleavage at moderate temperatures [Ago] (Mus musculus) PubMed

 24402.

This study evaluated the regulation of the YbjX and pagP transcription systems.[YbjX; pagP] (Mus musculus) PubMed

 24403.

although the plasmid amplification mechanism is well established, the partitioning system and the means by which the 2-micron plasmid partitioning proteins, Rep1 and Rep2, regulate plasmid copy number remain incompletely understood. (Mus musculus) PubMed

 24404.

Specificity of protein-DNA interactions in hypersaline environment: structural studies on complexes of Halobacterium salinarum oxidative stress-dependent protein RosR. [RosR] (Mus musculus) PubMed

 24405.

ERN1 is involved in regulating NIN expression in addition to CYCLOPS, and these transcription factors coordinately promote the symbiotic root hair response and infection thread development. The data help to reveal the extensive role of ERN1 in root nodule symbiosis signaling.[ERN1,CYCLOPS] (Mus musculus) PubMed

 24406.

Manipulating activities of mTORC1/AMPK in the absence of nutrient withdrawal is sufficient for a growth-to-developmental fate switch in Dictyostelium, providing a means to identify transcriptional networks and signaling pathways essential for early development.[mTORC1;AMPK] (Mus musculus) PubMed

 24407.

Distinct RNA-binding modules in a single PUF1 protein cooperate to determine RNA specificity in Schizosaccharomyces pombe. [PUF1] (Mus musculus) PubMed

 24408.

PtXSP25 protein produced in shoots and/or in roots under short-day conditions and at non-freezing low temperatures followed by translocation via xylem sap to shoot apoplast may protect the integrity of the plasma membrane and cell wall functions from freezing and drying damage in winter environmental conditions.[XSP25] (Mus musculus) PubMed

 24409.

Taken together, the luxS/AI-2 quorum sensing system in Haemophilus parasuis not only plays an important role in growth and biofilm formation, but also affects the pathogenicity of Haemophilus parasuis.[luxS] (Mus musculus) PubMed

 24410.

the network regulated by OS1 accomplishes a key step in nutrient allocation between endosperm and embryo within maize seeds.[OS1] (Mus musculus) PubMed

 24411.

Taken together, these findings indicate that Burkholderia pseudomallei BimC plays an important role in intracellular behavior and virulence of this emerging pathogen.[BimC] (Mus musculus) PubMed

 24412.

sigmaI/anti-sigmaI factors represent a distinctive mode of sigma/anti-sigma complex formation, which provides the structural basis for understanding the molecular mechanism of the intricate sigmaI/anti-sigmaI system in Clostridium thermocellum [SiglC, RsglIN] (Mus musculus) PubMed

 24413.

These results suggest that BspC and the vimentin interaction is critical for the pathogenesis of Group B Streptococcus meningitis. (Mus musculus) PubMed

 24414.

These results provide novel insight into the role of ZmDDM1 in regulating the formation of (m) CHH islands.[ZmDDM1] (Mus musculus) PubMed

 24415.

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites. (Mus musculus) PubMed

 24416.

The general mRNA exporters Mex67 and Mtr2 play distinct roles in nuclear export of tRNAs in Trypanosoma brucei. [Mex67], [Mtr2] (Mus musculus) PubMed

 24417.

Brucella ovis encodes a bacterial subclass 1 ferredoxin-NADP(H) reductase (BoFPR) that, by similarity with other FPRs, is expected either to deliver electrons from NADPH to the redox-based metabolism and/or to oxidize NADPH to regulate the soxRS regulon that protects bacteria against oxidative damage. The architecture of the FAD folded conformation in BoFPR might be key in catalysis (Mus musculus) PubMed

 24418.

VidA is a putative transcription factor that plays a key role in governing proper fungal growth, asexual and sexual development, and conidia formation.[VidA] (Mus musculus) PubMed

 24419.

Protonemata were treated with different concentrations (0 muMu, 5 muMu, 50 muM) of 6-benzylaminopurine (BAP) and the expression levels of the PpBOPs were measured. After the BAP treatment, the expression level of PpBOP1 and PpBOP3, but not PpBOP2, increased in a BAP concentration-dependent manner.[BOP2,BOP3] (Mus musculus) PubMed

 24420.

the DNA-binding site of the complex and present a model in which CBF3 induces a tight bend in centromeric DNA, was identified.[Cbf3a, Cbf3b] (Mus musculus) PubMed

 24421.

LC3 lipidation is required for degradation of the corpse membrane after lysosome fusion.[LC3] (Mus musculus) PubMed

 24422.

during latent infection when ICP27 is absent, HSV-1 likely takes advantages of host splicing machinery to restrict expression of randomly activated antigenic viral genes to achieve immune evasion. (Mus musculus) PubMed

 24423.

viral A26 protein functions as an acid-sensitive fusion suppressor during vaccinia mature virus endocytosis. (Mus musculus) PubMed

 24424.

TbArl13 localizes to the flagellum and associates with the axoneme. [TbArl13 ] (Mus musculus) PubMed

 24425.

This study defines the Sig-1R as an upstream modulator of canonical autophagy.[Sig-1R] (Mus musculus) PubMed

 24426.

These results indicate that OsbHLH058 and OsbHLH059 positively regulate major iron deficiency responses in a similar but distinct manner, and that this function may be partially controlled by OsHRZs. [OsHRZ1; OsbHLH058;OsbHLH059) (Mus musculus) PubMed

 24427.

These data show that CvsSR is a key regulator that controls calcium precipitation on the surface of bacterial cells.[CvsSR] (Mus musculus) PubMed

 24428.

These data suggest a novel mechanism by which Citrobacter rodentium and possibly other Gram-negative bacteria can negatively affect OMV production through the PmrAB-regulated genes pmrC (eptA) and cptA.[pmrC, cptA] (Mus musculus) PubMed

 24429.

Here, the authors show that HubP also recruits a transmembrane multidomain protein, PdeB, to the flagellated cell pole.[HubP, PdeB] (Mus musculus) PubMed

 24430.

The authors propose that Vrl1 regulate autophagy in a similar way as Vps9, and the level of Vrl1 partly decreases through both autophagy-dependent and -independent routes. [Vrl1] (Mus musculus) PubMed

 24431.

CKII phosphorylation of Spt6 promotes the interaction of Spt6 with Spn1, a binding partner required for chromatin reassembly and full recruitment of Spt6 to genes.[CKII, Spn1, Spt6] (Mus musculus) PubMed

 24432.

TGEV infection can inhibit the activation of the NF-kappaB signaling pathway, which is mainly mediated by Nsp3 through the canonical pathway [Nsp3]. (Mus musculus) PubMed

 24433.

Only Streptococcus suis type C sortase gene SrtF is essential for disease in Galleria mellonella, but that both SrtB and SrtF are essential for S. suis to cause systemic disease in pigs, and while both mutants still colonize the tonsils of pigs their numbers are reduced compared to the wild-type parental strain P1/7. (Mus musculus) PubMed

 24434.

YnbB is dedicated to synthesis of glycolipid MPIase involved in protein integration. [MPIase, YnbB] (Mus musculus) PubMed

 24435.

Determined is the crystal structure of group A Streptococcal surface dehydrogenase (SDH) at 1.74A. [surface dehydrogenase group A] (Mus musculus) PubMed

 24436.

The linear correlation between the somatic cell count and aerobic mesophyle general organism, milk cell NADPH, total protein and glucose-6-phosphate dehydrogenase suggests that these parameters could be used as markers of mastitis.[glutathione peroxidase] (Mus musculus) PubMed

 24437.

transcription was reconstituted from highly purified components on a ribosomal protein gene (RPS5) and discovered that TFIIDDeltaTBP binds and rearranges the promoter DNA topology independent of TBP.[TFIID, RPS5] (Mus musculus) PubMed

 24438.

Mir-156 expression and role in spiky pod development.[Mir-156] (Mus musculus) PubMed

 24439.

the present study identifies NECC2 as a component of adipocyte caveolae that is regulated in response to obesity and associated metabolic complications, and supports the contribution of this protein as a molecular scaffold modulating insulin signal transduction at these membrane microdomains. (Mus musculus) PubMed

 24440.

Lipoteichoic acid synthase YfnI is specifically phosphorylated by PrkC on Thr297.[YfnI] (Mus musculus) PubMed

 24441.

MPE exemplifies a novel clade of DNA endonuclease within the binuclear metallophosphoesterase superfamily. (Mus musculus) PubMed

 24442.

The overall structure of molybdopterin synthase was hetero-tetrameric, consisting of a MoaE2 dimer flanked on either side by single MoaD2 subunits. The carboxyl-terminal domain of MoaD2 inserted into MoaE2, forming the active pocket. [MoaD2] (Mus musculus) PubMed

 24443.

The overall structure of molybdopterin synthase was hetero-tetrameric, consisting of a MoaE2 dimer flanked on either side by single MoaD2 subunits. The carboxyl-terminal domain of MoaD2 inserted into MoaE2, forming the active pocket. [molybdopterin synthase] (Mus musculus) PubMed

 24444.

Scp160p may affect many processes via aggregation of Q/N-rich proteins.[Scp160p] (Mus musculus) PubMed

 24445.

This paper encompasses on the characterization of carbonic anhydrase gene and evaluating the ability of carbonic anhydrase in CO2 sequestration in a soil microcosm. [carbonic anhydrase] (Mus musculus) PubMed

 24446.

Staphylococcus aureus Coa binds with a significantly higher affinity to soluble fibrinogen than to fibrinogen coated on a plastic surface, whereas vWbp demonstrates no preference between the two forms of fibrinogen.[Coa, vWbp] (Mus musculus) PubMed

 24447.

The combined data strongly support that the two CXXC motifs and four cysteines constitute the structural site essential for Zn-coordination, protein dimerization, and the unique regulatory activity of BosR.[BosR] (Mus musculus) PubMed

 24448.

Study revealed that Chlamydia muridarum R51G GrgA allele is both necessary and sufficient for the low level of benzal-N-acylhydrazones (BAH) anti-chlamydials resistance. Thus, the Chlamydia-specific transcription factor GrgA either is a direct target of BAH or regulates BAH susceptibility.[GrgA] (Mus musculus) PubMed

 24449.

structure and functions of CntK in staphylopine synthesis [CntK] (Mus musculus) PubMed

 24450.

Our findings indicate that in combination with miR-19, miR-17 is a potent inducer of skeletal muscle differentiation. (Mus musculus) PubMed

 24451.

ATP binding to Rad5 induces the unwinding of the leading arm of the replication fork and proximally positions the leading and lagging arms.[Rad5] (Mus musculus) PubMed

 24452.

Fork reversal fails when CMG unloading is inhibited, but it does not require FANCI-FANCD2.[CMG] (Mus musculus) PubMed

 24453.

Fluorescence microscopy analyses indicate that binding of SipL's LysM domain to SpoIVA is required for SipL to localize to the forespore while SpoIVA requires SipL to promote encasement of SpoIVA around the forespore.[SipL, SpoIVA] (Mus musculus) PubMed

 24454.

Here the authors show that CstIV and CstV are involved in Campylobacter coli lipooligosaccharide biosynthesis. In particular, cstV is associated with lipooligosaccharide sialylation, while cstIV is linked to the addition of a diacetylated nonulosonic acid residue.[CstIV, CstV] (Mus musculus) PubMed

 24455.

The MrSVP gene contributes to thermotolerance and virulence of M. robertsii. Furthermore, this gene is deeply involved in the mycosis of insect cadavers and in immune escape rather than insect cuticle penetration during infection [MrSVP]. (Mus musculus) PubMed

 24456.

Cachd1 influences both CaV2.2 trafficking and function and can inhibit responses to alpha2delta-1.[Cav2.2] (Mus musculus) PubMed

 24457.

Genetic data and growth studies support a model whereby the Pseudomonas aeruginosa DeltapqsL mutant overproduces siderophores and thus likely outcompetes Streptococcus sanguinis for limited iron.[pqsl] (Mus musculus) PubMed

 24458.

Taken together, these results suggest that the DeltacysL mutation activates Spx, which then inhibits biofilm formation through repression of the eps operon.[cysL, Spx] (Mus musculus) PubMed

 24459.

Analysis of recombinant Sht and ShtII from Streptococcus agalactiae reveals that both proteins have similar affinities for factor H binding. However, neither protein aided in resistance to complement in human blood.[Sht, ShtII] (Mus musculus) PubMed

 24460.

P24 protein plays an important role in Grapevine leafroll-associated virus 2 pathogenesis, eliciting systemic necrosis.The 1-180 region is responsible for p24 to induce systemic necrosis.[GLRaV-2 p24 protein] (Mus musculus) PubMed

 24461.

preferred DNA-binding sequences for the Thermus thermophilus HB8 transcriptional repressor TTHA0973, is reported.[TTHA0973] (Mus musculus) PubMed

 24462.

the recruitment and transference of histone chaperone CIA/ASF1 is highly favored by its interaction with DBD(CCG1) via conformational selection and asymmetric binding.[ASF1] (Mus musculus) PubMed

 24463.

Hsp25.9 confers heat, salt, and drought stress tolerance to plants by reducing the accumulation of reactive oxygen species, enhancing the activity of antioxidant enzymes, and regulating the expression of stress-related genes.[Hsp25.9] (Mus musculus) PubMed

 24464.

The hepatitis C virus RNA-dependent RNA polymerase directs incoming nucleotides to its active site through magnesium-dependent dynamics within its F motif. (Mus musculus) PubMed

 24465.

The carbon monoxide dehydrogenase accessory protein CooJ is a histidine-rich multidomain dimer containing an unexpected Ni(II)-binding site. (Mus musculus) PubMed

 24466.

The role of MAPK kinases (MAPKKs/MKKs/MEKs) in the regulation of plant resistance to herbivores has not been extensively investigated. This study found that mechanical wounding, infestation of brown planthopper Nilaparvata lugens, and treatment with methyl jasmonate or salicylic acid could induce the expression of MKK3. [MKK3] (Mus musculus) PubMed

 24467.

XPG-related nucleases are hierarchically recruited for double-stranded rDNA break resection. (Mus musculus) PubMed

 24468.

Condensin D is reported and characterized. Condensin D, is composed of the core condensin proteins, Smc2 and Smc4, and two unique subunits, the kleisin Cph5 and Cpd2. Condensin D is required for sexual reproduction and for endoreplication and genome reduction of the progeny's somatic nuclei. (4 genes: Smc2, Smc4, Cph5, Cpd2) (Mus musculus) PubMed

 24469.

Ppg1 and the Far complex cooperatively dephosphorylate Atg32 to prevent excessive mitophagy.[Ppg1, Atg32, CK2] (Mus musculus) PubMed

 24470.

SarA is necessary and sufficient for STAT3 phosphorylation, STAT3 inhibition blocks IL-10 production, and SarA and STAT3 interact by co-immunoprecipitation.[SarA] (Mus musculus) PubMed

 24471.

MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM. [long non-coding RNA ODSM] (Mus musculus) PubMed

 24472.

Collectively, these results indicate a role for SopB in modulating the onset of necroptosis to increase bacterial pathogenesis and translocation to systemic sites.[SopB] (Mus musculus) PubMed

 24473.

The expression of NlOA2B3 and NlOA3 was relatively higher in egg and first instar nymph stage than in other stages and other receptor genes. All of these receptor genes were more highly expressed in brain than other tissues.[OA2B3,OA3] (Mus musculus) PubMed

 24474.

Findings indicate that manganese (Mn) sensing and gene regulation by metalloregulator MtsR are critical processes during Streptococcus pyogenes infection: [MtsR] (Mus musculus) PubMed

 24475.

Enforcing Tel1 recruitment to the nuclear MR complex fully rescues end tethering and stalled replication fork stability, and suppresses gross chromosome rearrangements, highlighting important roles for Xrs2 and Tel1 to ensure optimal MR complex activity.[Xrs2, Tel1] (Mus musculus) PubMed

 24476.

After treatment of T. castaneum larvae with carbofuran or dichlorvos insecticides, the transcript levels of Tcest4 and Tcest6 were significantly induced from 12 to 72 h. RNAi against Tcest4 or Tcest6 led to the higher mortality compared with the controls after the insecticides treatment, suggesting that these two genes play a vital role in detoxification of insecticides in T. castaneum.[Est-4] (Mus musculus) PubMed

 24477.

The knock out mutant Dhsit4Delta showed sensitivity towards Li(+), Na(+) and cell wall damaging agents; expression of DhSit4p rescued salt, caffeine and calcofluor white sensitivity of Dhmpk1Delta strain indicating a genetic interaction of this phosphatase with the cell wall integrity pathway in this species; study also showed the antagonistic roles of DhSit4p and DhPpz1p in maintaining the cell cycle and ion hom...[SIT4] (Mus musculus) PubMed

 24478.

NS12 located between NS16 and NS31 in segment 7 (S7) of the virus genome and is a transmembrane protein.[NS12] (Mus musculus) PubMed

 24479.

expressive identification and localization of bicoid-interacting protein 3 in the toxoplasma gondii Chinese I genotype Wh3 strain [bin3] (Mus musculus) PubMed

 24480.

This study provides an in-depth analysis of the role of miR-30-5p in the pathogenesis of myocardial infarction in mice. (Mus musculus) PubMed

 24481.

FNR represses the expression of virulence genes of Salmonella pathogenicity island 1 (SPI-1) and negatively regulates propanediol utilization by directly binding to the promoter region of the pdu operon. [FNR] (Mus musculus) PubMed

 24482.

Fur represses type VI secretion system function by binding directly to the clpV promoter in Salmonella typhimurium. [clpV] (Mus musculus) PubMed

 24483.

Nitric-oxide reductase (NorCB) knockout from Pseudomonas aeruginosa ATCC 9027 results in an increase in planktonic growth and biofilm formation compared to the wild type strains under aerobic conditions. Deletion of norCB leads to increased swimming ability and decreased pyocyanin production. Inactivation of norCB also leads to an increase of cellular H2 O2 concentration due to decreased activity of its catalases. (Mus musculus) PubMed

 24484.

Both the HPV6 E6 and E7 sequences were highly conserved within the analyzed patient samples in southwest China, indicating that the low risk HPV6 can adapt to the environment well without much evolution. [E6; E7] (Mus musculus) PubMed

 24485.

Mutation of NAL8 causes a reduction in the number of plastoglobules and shrunken thylakoids in chloroplasts, resulting in reduced cell division. In addition, the auxin levels in nal8 mutants are higher than in TQ, while the cytokinin levels are lower than in TQ.[NAL8] (Mus musculus) PubMed

 24486.

the transcription factors CONSTANS and Nuclear transcription Factor Ys (NF-Ys) form a complex that governs light-dependent photoprotective responses in C. reinhardtii.[Constans] (Mus musculus) PubMed

 24487.

Specific inhibition of GhFAD2-3 using the RNA interference approach resulted in male sterility due to impaired anther development at the stages from meiosis to maturation.[FAD2-3] (Mus musculus) PubMed

 24488.

The fuzzless gene GaFzl was fine mapped to a 70-kb region containing a GIR1 gene, Cotton_A_11941, responsible for the fuzzless trait in Gossypium arboreum DPL972.[GaFzl] (Mus musculus) PubMed

 24489.

evolution of DRO1-like wheat homoeologs might incorporate the C-terminus mutations as well as gain and loss of auxin response elements and other cis-regulatory elements during expression divergence.[DRO-1 like] (Mus musculus) PubMed

 24490.

Tetur07g02040 is not only the first spider mite dioxygenase that has been characterized at the molecular level, but is also the first structurally characterized intradiol ring-cleavage dioxygenase originating from a eukaryote.[tetur07g02040] (Mus musculus) PubMed

 24491.

Aminoglycoside antibiotic resistance conferred by Hpa2 of MDR Acinetobacter baumannii: an unusual adaptation of a common histone acetyltransferase. (Mus musculus) PubMed

 24492.

Biochemical investigations of the substrate scope of IsfD, and bioinformatics analysis of IsfD homologs, suggest that IsfD is related to the promiscuous 3-hydroxyacid dehydrogenases with diverse metabolic functions. (Mus musculus) PubMed

 24493.

Streptococcus oralis subsp. dentisani displays a striking monolateral distribution of surface fibrils. Mutagenesis studies indicate that these fibrils are dependent on three serine-rich repeat proteins (SRRPs), here named fibril-associated protein A (FapA), FapB, and FapC, and that each SRRP forms a different fibril with a distinct distribution. [FapA], [FapB], [FapC] (Mus musculus) PubMed

 24494.

The crystal structure of the GatD/MurT complex at high resolution revealed an open, boomerang-shaped conformation in which GatD is docked onto one end of MurT. Putative active site residues cluster at the interface between GatD and MurT and are contributed by both proteins. The 2 proteins approach each other during catalysis. GatD. MurT (Mus musculus) PubMed

 24495.

The full length NlNompC possessed similar structure as Drosophila melanogaster NompC, which belongs to TRPN subfamily. The expression pattern analysis of different developmental stages and body parts showed that the transcription of NlNompC was more abundant in adult stage and in the abdomen.[NompC] (Mus musculus) PubMed

 24496.

mitochondrial localization of PB1-F2 increased the potency of chicken IFN beta induction antagonism. [interferon beta] (Mus musculus) PubMed

 24497.

Study reports a number of crystal and high-resolution cryo-electron microscopy (cryo-EM) structures of the T7 bacteriophage portal (gp8).[gp8] (Mus musculus) PubMed

 24498.

Mitochondrial localization of PB1-F2 resulted in reduced antagonism of an NFkappaB-dependent promoter. (Mus musculus) PubMed

 24499.

The results suggested that BP7 might be an active biological factor that functions as a potential immunopotentiator, which provided some novel insights into the molecular mechanisms of the effects of bursal peptides on immune functions and B cell differentiation.[BP7] (Mus musculus) PubMed

 24500.

VtaA2 mediates adherence to the host by binding to the mucin, found in the upper respiratory tract mucus, and to the extracellular matrix proteins, present in the connective tissue of systemic sites, such as the serosa.[VtaA2] (Mus musculus) PubMed

 24501.

The data indicate a diverse role for norV in the expression of A. hydrophila virulence-associated traits that is not completely dependent on its function as a nitric oxide reductase.[norV] (Mus musculus) PubMed

 24502.

The complement-like proteins, TEP1, TEP3 and TEP4, are positive regulators of the functional integration between the immune and circulatory systems of mosquitoes.[TEP1, TEP3, TEP4] (Mus musculus) PubMed

 24503.

Chz1 controls the bioavailability of H2A.Z to assist SWR1 in promoter-specific installation of a histone mark.[Chz1] (Mus musculus) PubMed

 24504.

CCN3 promotes the expression of Runx2 and osterix in osteoblasts by inhibiting miR-608 expression via the FAK and Akt signaling pathways.[miR608] (Mus musculus) PubMed

 24505.

These findings reveal a new regulatory mechanism of MLPK in the Self-Incompatibility of B. napus.[MLPK] (Mus musculus) PubMed

 24506.

CaCDC50 regulates cellular responses to antifungal drugs, cell membrane stress, endocytosis, filamentation and virulence in the human fungal pathogen C. albicans [CDC50]. (Mus musculus) PubMed

 24507.

grain weight is associated with the GNI-A1 gene, a regulator of floret fertility.[GNI-A1] (Mus musculus) PubMed

 24508.

Cyt2Aa2 toxin binds preferentially to the Ld lipid bilayer containing 1-palmitoyl,2-oleoyl-sn-glycero-3-phosphocholine. [Cyt2Aa2] (Mus musculus) PubMed

 24509.

positive covariance between maternal expression and offspring fitness [pgrp-sc2] (Mus musculus) PubMed

 24510.

Study shows the molecular cloning, overexpression, and characterization of the KGUK enzyme (2-ketogluconate kinase) from C. necator H16 and demonstrated that KDG is a substrate for this enzyme and that some KG and KDG epimers can also be converted into the corresponding phosphorylated derivatives. [KGUK] (Mus musculus) PubMed

 24511.

Cultivar Zvezdana was the only one that showed increase in EF-Tu accumulation under HT (25%) compared to MT. Immunoblot analysis indicated that the highest increase of eEF1A accumulation (43%) in relation to moderate temperature was detected in cultivar Talas.[EF-Tu, eEF1A] (Mus musculus) PubMed

 24512.

The authors identified a deleterious mutation (G239R) that altered a highly conserved amino acid residue in the zebrafish ortholog of type I polyketide synthase (pks1) to underlie these phenotypes and showed that expression of the polyketide synthase gene of Japanese medaka fish could rescue the otolith deficiency in not1 mutant zebrafish. [PKS1] (Mus musculus) PubMed

 24513.

Data found that c-di-GMP strongly binds to CobB inhibiting its deacetylation activity. A major diguanylate cyclase, DgcZ, is endogenously acetylated and CobB enhances the stability and activity of DgcZ as a consequence of deacetylation. These results propose that there is a negative feedback loop between c-di-GMP and CobB that is important for maintaining the proper cellular concentration of c-di-GMP. [CobB, DgcZ] (Mus musculus) PubMed

 24514.

The enzymatic accessory ribonucleoprotein complex, termed the REH2C, includes mRNA substrates and products, the multi-domain 240 kDa RNA Editing Helicase 2 (REH2) and an intriguing 8-zinc finger protein termed REH2-Associated Factor 1 (H2F1). The recombinant REH2 (240 kDa) established that the full-length protein is a bona fide RNA helicase with ATP-dependent unwinding activity. [RNA Editing Helicase 2] (Mus musculus) PubMed

 24515.

FTRCA1, a Species-Specific Member of finTRIM Family, Negatively Regulates Fish IFN Response through Autophage-Lysosomal Degradation of TBK1. (Mus musculus) PubMed

 24516.

Genetic and molecular analysis indicated that SMK6 is the maize ortholog of the Arabidopsis SLO2, which is a component of the PPR-E+/NVWA/DYW2 editing complex. However, yeast two-hybrid analyses did not detect any interaction between SMK6 and any of the mitochondrion-targeted RIPs/MORFs.[SMK6] (Mus musculus) PubMed

 24517.

analysis of the RNA-based thermosensor within the 5' UTR of Staphylococcus aureus cidA [cidA] (Mus musculus) PubMed

 24518.

This study reports the X-ray crystallographic structure of the glycyl-tRNA synthetase (GlyRS) of Nanoarchaeum equitans. [glycyl-tRNA synthetase ] (Mus musculus) PubMed

 24519.

mir156 mutations enhance seed dormancy by suppressing the gibberellin (GA) pathway through de-represssion of the miR156 target gene Ideal Plant Architecture 1 (IPA1), which directly regulates multiple genes in the GA pathway. [mir156] (Mus musculus) PubMed

 24520.

The authors show that processing of norovirus NS1/2 yields NS1, an unconventionally secreted viral protein that is central for IFN-lambda resistance. Murine norovirus infection globally suppresses intestinal IFN-lambda responses, which is attributable to secreted NS1. (Mus musculus) PubMed

 24521.

Overexpression of the OsSCE3 gene in transgenic rice plants enhances drought stress tolerance. In contrast, OsSCE1-OX transgenic rice plants are hypersensitive to drought stress.[SCE3] (Mus musculus) PubMed

 24522.

Overexpression of TaEXPB7-B in Arabidopsis promoted a significant increase in plant growth and increased lignin and cellulose contents. Moreover, TaEXPB7-B conferred enhanced antioxidant and osmotic regulation in transgenic Arabidopsis, thereby increasing the tolerance and survival of plants under conditions of low-temperature stress.[EXPB7-B] (Mus musculus) PubMed

 24523.

LjNPF2.9 plays a crucial role in the downward transport of nitrate to roots, occurring likely through a xylem-to-phloem loading-mediated activity.[NPF2.9] (Mus musculus) PubMed

 24524.

a non-LTR retrotransposon that activates anthocyanin biosynthesis by regulating a MYB transcription factor - [nLTR-A] (Mus musculus) PubMed

 24525.

GhWIN2 not only regulated the cuticle biosynthesis pathway, but also positively influenced JA biosynthesis and negatively influenced SA biosynthesis.[WIN2] (Mus musculus) PubMed

 24526.

essential for stigmatic mucilage production - [GALT2] (Mus musculus) PubMed

 24527.

circAnks1a and VEGFB are regulators of neuropathic pain.[CircAnks1a] (Mus musculus) PubMed

 24528.

MiR-506 modulated osteoclastogenesis by targeting SIRT1 expression in part through modulation of the TRPV1 channel, ROS production, and TNF-alpha. (Mir-506) (Mus musculus) PubMed

 24529.

the cryo-electron microscopy structures of intact Drs2p-Cdc50p isolated from S. cerevisiae in apo form and in the phosphatidylinositol-4-phosphate-activated form at 2.8 A and 3.3 A resolution, respectively, are reported.[Drs2,Cdc50] (Mus musculus) PubMed

 24530.

Expression of SGD2 was pronounced in developing panicles, and its protein was localized in nucleus. Luciferase reporter system and transactivation assays in yeast suggested that SGD2 functioned as a transcriptional repressor.[sgd2] (Mus musculus) PubMed

 24531.

LUGL is involved in regulating of floral development through auxin related process (LUGL). (Mus musculus) PubMed

 24532.

ZmSMK9 is a novel gene required for the splicing of nad5 intron-1 and intron-4, kernel development, and plant architecture in maize.[smk9] (Mus musculus) PubMed

 24533.

MdGRF11 acts as a positive regulator of salt and drought stress responses through regulating ROS scavenging and other signaling systems.[GRF11] (Mus musculus) PubMed

 24534.

The present results indicated that Enterovirus A structural viral protein 1 (VP1) promoted mouse Schwann cell autophagy. Overexpression of VP1 upregulated PMP22. [ structural viral protein 1] (Mus musculus) PubMed

 24535.

Ectopic expression of OsASR6 (ABA STRESS RIPENING6) had a remarkable effect on plant growth in Arabidopsis. Transgenic lines over-expressing OsASR6 had larger leaves, taller inflorescence bolts and greater numbers of siliques and seeds.[ASR6] (Mus musculus) PubMed

 24536.

In this study, a promising enzyme (KstD2) from Mycobacterium neoaurum DSM 1381 was purified and characterized. Interestingly, KstD2 displayed a high activity on a range of substrates, including 17alpha-hydroxypregn-4-ene-3,20-dione (17alpha-OH-P); androsta-4,9(11)-diene-3,17-dione (NSC 44826); and 4-androstene-3,17-dione (AD).[KstD2] (Mus musculus) PubMed

 24537.

Study presents cryo-EM structure of Chaetomium thermophilum Set2 bound to the mimic of H2B ubiquitinated nucleosome. Set2 makes extensive interactions with the H3 alphaN, the H3 tail, the H2A C-terminal tail and stabilizes DNA in the unwrapped conformation, which positions Set2 to specifically methylate H3K36. Ubiquitin contributes to Set2 positioning on the nucleosome and stimulates the methyltransferase activity.[Set2] (Mus musculus) PubMed

 24538.

The cyclodipeptide synthase (CDPS) homologous gene, sb1370, was involved in diketopiperazines synthesis and played an important role in quorum sensing.[sb1370] (Mus musculus) PubMed

 24539.

Using a coupled enzymatic assay with malate dehydrogenase, Vmax values between 20 and 25 mumol min(-1) mg(-1) were measured for purified pyruvate carboxylase corresponding to turnover numbers of 160 - 200 s(-1) for the tetrameric enzyme.[pyruvate carboxylase] (Mus musculus) PubMed

 24540.

Phylogenetic analysis revealed clustering of DDX3 and DHX9 with corresponding proteins from other fish. In the rainbow trout gonadal cell line, RTG-2, DHX9 localized mostly to the nucleus, while DDX3 was found mainly in the cytoplasm.[ddx3] (Mus musculus) PubMed

 24541.

Magnaporthe oryzae BIR1-overexpressing transformants exhibited anti-apoptotic activity. However, MoBIR1 silencing resulted in no obvious phenotypic changes, compared with the wild-type Magnaporthe oryzae strain Guy11.[BIR1] (Mus musculus) PubMed

 24542.

functionally characterized an epsilon-class glutathione S-transferase (GST) from a brown planthopper Nilaparvata lugens (nlGSTE). [nlGSTE] (Mus musculus) PubMed

 24543.

The observed decrease in ArdB protective activity in UV-treated cells is due to its binding to unmodified chromosomal DNA, which decreases effective concentrations of free ArdB molecules available for lambda phage protection against EcoKI restriction enzymes. [ArdB] (Mus musculus) PubMed

 24544.

CgSOCS6 was involved in the oyster immune response by regulating the expressions of CgIL17-4, CgIL17-5, and CgDefh1.[Defh1] (Mus musculus) PubMed

 24545.

LvCTLU might be involved in the shrimp ER-stress response. Reporter gene assay indicated that LvCTLU was regulated by X-box-binding protein 1, which is the key transcription factor in the UPR. This study thus revealed that LvCTLU plays vital roles in both the anti-pathogen immune response and the ER-stress response.[CTLU] (Mus musculus) PubMed

 24546.

Together, these data demonstrate that Streptococcus suis PmtA acts as a Fe(II) and Co(II) efflux pump, and contributes to oxidative stress resistance.[PmtA] (Mus musculus) PubMed

 24547.

Gas1p plays an important role in the ageing and endoplasmic reticulum stress responses in yeast.[GAS1] (Mus musculus) PubMed

 24548.

In nosocomial HCV transmission-clusters, the intra-host HCV quasispecies divergence in patients with acute-infection was very low in comparison to that in chronic-infection. The NS5A-RAS Y93H was often transmitted and distributed differently within the same transmission-clusters, independently from the IL-28-polymorphism.[NS5A] (Mus musculus) PubMed

 24549.

One gene strongly upregulated by the deletion of mcrA is llmG, a putative methyl transferase related to LaeA, a major regulator of secondary metabolism. [LaeA-like Methyltransferase] (Mus musculus) PubMed

 24550.

these results demonstrated that LPSinduced podocyte injury could be alleviated by the TUG1/miR197/MAPK1 axis. (Mus musculus) PubMed

 24551.

In conclusion, miR10b3p, miR8112 and let7j may be underlying biomarkers for diagnosing autoimmune inner ear disease. [let-7j] (Mus musculus) PubMed

 24552.

Alpha-synuclein inclusions do not display amyloid-like features until late in the life of the worms, whereas polyglutamine forms amyloid characteristics rapidly in early adulthood. [alpha-Synuclein ] (Mus musculus) PubMed

 24553.

Class IV lanthipeptide synthetases consist of an N-terminal lyase, a central kinase, and a C-terminal cyclase domain. This study presents the first in-depth characterization of such a kinase domain from the globisporin maturation enzyme SgbL that originates from Streptomyces globisporus sp. [SgbL] (Mus musculus) PubMed

 24554.

DopEcR could bind 20-hydroxyecdysone (20E) inside the cell membrane or after being isolated from the cell membrane. Mutation of DopEcR decreased 20E binding levels and related cellular responses. The results of the study suggested that 20E, via binding to DopEcR, arrests larval feeding and promotes pupation.[DopEcR] (Mus musculus) PubMed

 24555.

In Manduca, PLIN1B was expressed only in the 5th instar larva and its levels correlated with fat storage. Furthermore, PLIN1B levels increased with the fat content of the diet in insects of the same age confirming a direct relationship between PLIN1B and TG storage irrespective of development.[PLIN1B] (Mus musculus) PubMed

 24556.

MTase15 was readily detected from egg to adult stages and extensively distributed in various body parts of adult females and males, with slightly high levels in ovary and testis, respectively. In addition, MTase15 was transcriptionally regulated by the insulin signalling pathway in BPH. [MTase15] (Mus musculus) PubMed

 24557.

LcpRVH2 is a regulator of the TetR-family located 131 bp upstream of latex-clearing protein lcp1VH2. An inverted repeat in the intergenic region between lcpRVH2 and lcp1VH2 is identified being the binding site of LcpRVH2. LcpRVH2 also binds the operator region of lcp2VH2 and regulates their expression in G. polyisoprenivorans VH2. (Mus musculus) PubMed

 24558.

our study demonstrated that miR-181b could attenuate brain injury through down-regulating HSPA5 protein levels in vitro and in vivo. (Mus musculus) PubMed

 24559.

In vitro activation of transcription read-through of mgtA by Mn2+ is much greater than by Ca2+. mgtA mRNA and protein levels increase approximately 5-fold during cellular Mn stress, but only in genetic backgrounds that exhibit Mn2+ sensitivity. This riboswitch functions as a failsafe 'on' signal to prevent Mn2+ toxicity in the presence of high cellular Mn2+. mgtA. (Mus musculus) PubMed

 24560.

Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholera [DHO] (Mus musculus) PubMed

 24561.

Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholera [DHO] (Mus musculus) PubMed

 24562.

the structural arrangement and biological roles of Spc42 elements, is reported.[Spc42] (Mus musculus) PubMed

 24563.

PoIL-2 plays an important role in the induction of immune responses and immune defense against bacterial and virus infection, which indicated its potential use as an immunopotentiator to prevent diseases in flounder.[IL-2] (Mus musculus) PubMed

 24564.

The formation of the cationic channel is elucidated in atomic detail using molecular dynamics simulations on the all-trans-retinal (ChR2-trans) configuration of Channelrhodopsin-2 (ChR2) and its isomerization products, 13-cis-retinal (ChR2-cis) configuration, respectively. [Channelrhodopsin-2] (Mus musculus) PubMed

 24565.

CgIKKepsilon-like could respond to pathogenic infection, participate in the immune signal transduction and activate NF-kappaB and ISRE reporter genes. Thus, CgIKKepsilon-like could play an important role in the oyster immune system.[IKKepsilon] (Mus musculus) PubMed

 24566.

A naturally occurring bacterial DNA polymerase I member isolated from Geobacillus stearothermophilus exhibits an Innate ability to reverse transcribe RNA and other synthetic congeners (XNAs) into DNA. Analysis of the enzyme active site reveals the importance of structural plasticity as a possible mechanism for XNA-dependent DNA synthesis. (Mus musculus) PubMed

 24567.

Study reports a novel pentatricopeptide repeat-DYW protein EMP21 that is associated with editing of 81 sites in maize. EMP21 is localized in mitochondria and loss of the EMP21 function severely inhibits the embryogenesis and endosperm development in maize. [EMP21] (Mus musculus) PubMed

 24568.

RarA acts at the interplay between replication and repair-by-recombination [RarA] (Mus musculus) PubMed

 24569.

The Aedes aegypti salivary protein AaSG34 promotes DENV2 replication in mosquito salivary glands and enhances the transmission of the virus to the mammalian host. [AaSG34] (Mus musculus) PubMed

 24570.

This study shows that both Xenopus laevis voltage sensing phosphatases (Xl-VSP1 and Xl-VSP2 ) mRNAs are expressed in early embryos, suggesting that both Xl-VSPs are involved in early tadpole development. [Xl-VSP1, Xl-VSP2] (Mus musculus) PubMed

 24571.

Avo3 localized to the PM independent of both Avo1 and Tor2, whereas both Tor2 and Avo1 required Avo3 for their plasma membrane anchoring.[Avo1, Avo3] (Mus musculus) PubMed

 24572.

The inducible P2Y14R plays an important role in regulation of fish innate immunity.[P2Y14R] (Mus musculus) PubMed

 24573.

LvCTL5 was highly expressed in hepatopancreas and could be activated by infection with bacteria, virus and fungi. Silencing of LvCTL5 in vivo could significantly affect expression of a series of immune effector genes and down-regulate the phagocytic activity of hemocytes.[CTL5] (Mus musculus) PubMed

 24574.

a potent dominant negative mutant variant of Rad51 in Ustilago maydis [Rad51] (Mus musculus) PubMed

 24575.

This study focuses on examining the role of the putative polysaccharide synthase cpsA gene in A. fumigatus virulence.[CpsA] (Mus musculus) PubMed

 24576.

Snc1 is trafficked between the endosomal system and the Golgi apparatus via multiple pathways.[Snc1] (Mus musculus) PubMed

 24577.

The extracellular lipase was separated from Serratia marcescens. The separated enzyme was purified partially by ammonium sulfate precipitation, dialysis and gel filtration chromatography. Presence of the lipase in chromatography fractions was assayed by the hydrolysis of paranitrophenyl palmitate as substrate. [lipase] (Mus musculus) PubMed

 24578.

Mutations affect the binding mechanisms of the xpt-pbuX guanine riboswitch with its ligands. Mutations can strengthen the binding affinity of ligands GR. They affect interactions of ligands with key nucleotides U22, U51 and C74. They not only regulate the structural flexibility but also change the internal motion modes of GR, especially for the structures J12, J23 and J3. The aptamer domain activity of GR is thus tunable. (Mus musculus) PubMed

 24579.

The LMM24 gene was identified by MutMap, and LMM24 was confirmed as a receptor-like cytoplasmic kinase 109 by amino acid sequence analysis. The lmm24 mutant displayed dark brown lesions in leaves and growth retardation that were not observed in wild-type ZH8015. The results showed enhanced reactive oxygen species accumulation and cell death in lmm24. [lmm24] (Mus musculus) PubMed

 24580.

HmbA and HmbB play also a role in sensing of and response to environmental signals, while HmbC functionally interacts with VeA, a key regulator of the coordination of asexual and sexual development.[HmbA, HmbB, HmbC] (Mus musculus) PubMed

 24581.

we identified a pair of nonrearranging VJ-joined Ig superfamily genes, termed putative remnants of an Ag receptor precursor (PRARP) genes, in chicken (Mus musculus) PubMed

 24582.

Nap1 and Tsr4 are direct binding partners of Rps6 and Rps2, respectively.Tsr4 is specific for Rps2. Nap1 has several interaction partners including Rps6 and two other r-proteins. Tsr4 is specific for Rps2, Nap1 has several interaction partners including Rps6 and two other r-proteins. Nap1. Tsr4. (Mus musculus) PubMed

 24583.

SrcA was not required for SPI-2 T3SS-dependent, neutral pH-induced secretion of either SseL or PipB2 but was essential for secretion of SteD. [SrcA, SteD] (Mus musculus) PubMed

 24584.

the role of clathrin and clathrin adaptors in megalin's apical localization and trafficking, was studied.[AP-1gamma1, AP-1gamma2] (Mus musculus) PubMed

 24585.

the results predict a hetero-oligomeric structure for the T. cruzi mitochondrial calcium uniporter complex, with structural and functional differences, as compared with those in the mammalian complex.[TcMCUc, TcMCUd] (Mus musculus) PubMed

 24586.

The C4-type Zn finger motif present in the C-terminus of DksA is essential for optimal cholera toxin production. [DksA] (Mus musculus) PubMed

 24587.

Bacillus subtilis RadA/Sms contributes to chromosomal transformation and DNA repair in concert with RecA and circumvents replicative stress in concert with DisA [RadA][RecA][DisA] (Mus musculus) PubMed

 24588.

In Bombyx mori, ninaB was almost exclusively expressed in female reproductive organs of the pupa and adult. In Tribolium castaneum, low expression was found in reproductive organs of females but high expressions in male reproductive organs of the pupa and imagoes.[NinaB] (Mus musculus) PubMed

 24589.

drl1 and drl2 regulate floret development by imposing floral meristem determinacy [DRL1; DRL2] (Mus musculus) PubMed

 24590.

A single glycine was introduced in the hinge region connecting both domains of the enzyme involved in its catalytic activity (NTase and OB domains). In silico, the mutant enzyme bound to dsXNA showed that the insertion of this glycine results in stable complexes that keep a closed conformation during molecular dynamics. In vitro, this glycine insert introduced high ligation efficiency of XNA fragments on anXNA template. (Mus musculus) PubMed

 24591.

CYP9Q6 is an efficient metaboliser of N-cyanoamidine neonicotinoids and likely plays a key role in the high tolerance of Bombus terrestris to these insecticides. [CYP9Q6] (Mus musculus) PubMed

 24592.

The current data strongly suggest that Src64B1 and Src64B2 are host factosr that inhibits white spot syndrome virus replication by modulating apoptosis in shrimp (Src64B1 and Src64B2). (Mus musculus) PubMed

 24593.

This study demonstrates that a cerato-platanin (CP) protein, FocCP1, functions as a virulence factor that is required by Fusarium oxysporum f. sp. cubense Tropical Race 4 for penetration and full virulence. [cerato-platanin protein] (Mus musculus) PubMed

 24594.

two phosphorylation sites of RsbR are functional in L. monocytogenes under acidic conditions, similar to the situation in B. subtilis (RsbR). (Mus musculus) PubMed

 24595.

Knockdown of lnc-ORA (obesity-related lncRNA), inhibited adipocytes differentiation by regulating the PI3K/AKT/mTOR signaling pathway. lnc-ORA was transcribed from locus 89,767,653 to locus 89,768,886 on chromosome 15 and consisted of two exons and one intron. [lnc-ORA] (Mus musculus) PubMed

 24596.

These observations suggest that Hag/MID, a major adhesin, is important for initial colonization by M. catarrhalis and that cessation of expression facilitates persistence in COPD airways. [Hag/MID] (Mus musculus) PubMed

 24597.

These findings suggest that yersiniabactin (Ybt) establishes a profibrotic environment in the host in the absence of binding to its cognate receptor and indicate a direct link between intestinal AIEC and the induction of inflammation-associated fibrosis.[Ybt] (Mus musculus) PubMed

 24598.

qKRN5b is a QTL underlying kernel row number in Zea mays (Mus musculus) PubMed

 24599.

Crystal structure of Beta-N-acetylhexosaminidase from Akkermansia muciniphila was built firstly. Beta-N-acetylhexosaminidase and its complex with N-Acetylglucosamine provide obvious structural evidence for substrate-assisted catalysis. [Beta-N-acetylhexosaminidase] (Mus musculus) PubMed

 24600.

Long non-coding RNA lnc-OAD was up-regulated expression during 3T3-L1 differentiation and stable knockdown of lnc-OAD inhibited adipocyte differentiation in 3T3-L1 cells. [Long non-coding RNA lnc-OAD] (Mus musculus) PubMed

 24601.

This study solved the crystal structure of the non-structural protein 5 complexed with a Michael acceptor-based inhibitor, N3. Structural analysis revealed that the Cbeta of the vinyl group of N3 covalently bound to C145 of the catalytic dyad of M(pro), which irreversibly inactivated cysteine protease activity. [non-structural protein 5] (Mus musculus) PubMed

 24602.

To understand the role of the fifth subunit in phiKZ non-canonical non-virion RNA polymerase (nvRNAP), created was a co-expression system allowing to get recombinant full five-subunit (5s) and four-subunit (4s) complexes and performed was their comparison. The 5s recombinant complex is active on phage promoters in vitro as the native nvRNAP. [nvRNAP] (Mus musculus) PubMed

 24603.

The antibiotic moenomycin A is a phosphoglycerate derivative with a C25-moenocinyl chain and a branched oligosaccharide. Formation of the C25-chain is catalyzed by the enzyme MoeN5 . The complex crystal structures of MoeN5 with two 2-Z,E-farnesyl-3-phosphoglycerate analogs were determined [MoeN5] (Mus musculus) PubMed

 24604.

the natural variation of Molybdenum concentration in rice grains is attributed to the variable expression of OsMOT1;1 due to sequence variation in its promoter.[OsMOT1;1] (Mus musculus) PubMed

 24605.

The enzymatic activities of three midgut chitin deacetylases toward peritrophic membrane chitin were determined. BmCDA7 exhibited the highest activity (0.284mumol/min/mumol), while BmCDA8 showed lower activity of 0.061mumol/min/mumol, and BmCDA6 was inactive.[CDA6,CDA7,CDA8] (Mus musculus) PubMed

 24606.

Disruptions of Doublesex (DSX) sex-specific isoforms caused sex-specific defects in external genitals and partial sexual reversal. Mutations also caused changes in expression of several sex-biased genes and induced sex-specific sterility. This suggests novel genetic control approaches for the management of P. xylostella (Mus musculus) PubMed

 24607.

The results indicated that melanin production in melanocytes could be increased by manipulating miR1435p expression using Short tandem target mimic (STTM) which resulted in melanogenesis (ASM) and eumelanin (EM) production. [eumelanin] (Mus musculus) PubMed

 24608.

Results confirm that the binding of Mis19 to Mis18 requires the very N terminus of Mis19. In addition, two conserved motifs were identified in Mis19 that seem to mediate the binding. Each motif is characterized by a set of closely spaced, totally conserved hydrophobic residues. [Mis19] (Mus musculus) PubMed

 24609.

This study reports the characterization of an Sucrose 6(F)-phosphate phosphorylase (SPP) from Ilumatobacter coccineus with a far stricter specificity than the previously described promiscuous SPP from Thermoanaerobacterium thermosaccharolyticum. Crystal structures of both SPPs were determined to provide insight into their similarities and differences. [Sucrose 6(F)-phosphate phosphorylase] (Mus musculus) PubMed

 24610.

This study reports the characterization of an Sucrose 6(F)-phosphate phosphorylase (SPP) from Ilumatobacter coccineus with a far stricter specificity than the previously described promiscuous SPP from Thermoanaerobacterium thermosaccharolyticum. Crystal structures of both SPPs were determined to provide insight into their similarities and differences. [Sucrose 6(F)-phosphate phosphorylase] (Mus musculus) PubMed

 24611.

The fatty acid synthase gene BgFas1 is necessary for both hydrocarbon and cuticular fatty acid biosynthesis in Blatella germanica.[BgFas1] (Mus musculus) PubMed

 24612.

ABCA2 is essential for the toxicity of Cry2Ab in Trichoplusia ni and mutation of ABCA2 confers the resistance to the Bt toxin Cry2Ab in the resistant T. ni strain derived from a Bt resistant greenhouse population. (Mus musculus) PubMed

 24613.

qkrnw4 is a major quantitative trait locus associated with kernel row number in maize [qkrnw4] (Mus musculus) PubMed

 24614.

Treatment of chronic HCV infection with DAAs in Rio de Janeiro/Brazil: SVR rates and baseline resistance analyses in NS5A and NS5B genes. (Mus musculus) PubMed

 24615.

Som1 and Vta3 regulate developmental genetic networks required for conidiation, microsclerotia formation and pathogenicity of V. dahliae.[Som1, Vta3] (Mus musculus) PubMed

 24616.

Employed was mutational analysis to demonstrate that the two proteases, termed "thetapain" and "iotapain", undergo in trans autoactivation after lysine and/or arginine residues, as observed for other C11 proteases. Determined are the structures of the active forms of thetapain and iotapain in complex with irreversible peptide inhibitors, Ac-VLTK-AOMK and biotin-VLTK-AOMK, respectively. [thetapain, iotapain] (Mus musculus) PubMed

 24617.

In the yeast Saccharomyces cerevisiae the efficient incorporation of Mnn4, a type II membrane protein required for mannosyl phosphate transfer to glycoprotein-linked oligosaccharides, into COPII vesicles is dependent on the function of the ER exit adaptor protein Svp26. Mnn4 is localized to the Golgi, and mannosyltransferase Mnn6 localizes to the ER. Svp26 and Mnn6 facilitate the incorporation of Mnn4 into COPII vesicles. (Mus musculus) PubMed

 24618.

functional characterization of 70-kDa heat shock protein, DnaK, from Bacillus halodurans [DnaK] (Mus musculus) PubMed

 24619.

New ERG11-associated azole resistance and FKS1-associated echinocandin resistance in Candida auris have been found.[ERG11] (Mus musculus) PubMed

 24620.

Results with Bordetella bronchiseptica RB50 6-Hydroxynicotinate 3-monooxygenase (NicC) show that a homocyclic analogue of 6-hydroxynicotinic acid (6-HNA), 4-hydroxybenzoic acid (4-HBA), is decarboxylated and hydroxylated by NicC with a 420-fold lower catalytic efficiency than is 6-HNA. [6-Hydroxynicotinate 3-monooxygenase] (Mus musculus) PubMed

 24621.

Exo70F3, required for Pii-mediated resistance, is dispensable for Pi5-mediated resistance.[Pii, Pi5] (Mus musculus) PubMed

 24622.

two candidate genes, RsANNAT and RsCDPK, seemed to be responsible for root cracking in radish [RsANNAT; RsCDPK] (Mus musculus) PubMed

 24623.

These findings provide new insights into the ubiquitination of MdbHLH3 by glucose-inhibited ubiquitin E3 ligase MdPUB29 in the regulation of ethylene biosynthesis.[MdbHLH3, MdPUB29] (Mus musculus) PubMed

 24624.

Pkd2p modulates osmotic homeostasis and is potentially a novel regulator of cytokinesis.[Pkd2p] (Mus musculus) PubMed

 24625.

WDR92 is a key assembly factor specifically required for the stability of axonemal dynein heavy chains in cytoplasm.[WDR92] (Mus musculus) PubMed

 24626.

PACRG and FAP20 comprise the inner junction bridge that serves as a hub for both directly modulating dynein-driven microtubule sliding.[PACRG, FAP20] (Mus musculus) PubMed

 24627.

Elg1 plays a role in the induction of the DNA damage checkpoint, a cellular response to DNA damage [Elg1]. (Mus musculus) PubMed

 24628.

Pdr1 function is responsive to ergosterol biosynthesis [Pdr1]. (Mus musculus) PubMed

 24629.

The plasmid-mediated mobile tigecycline resistance mechanism Tet(X4) in Escherichia coli isolates is capable of degrading all tetracyclines, including tigecycline and eravacycline. In vivo murine models demonstrates that the presence of Tet(X4) leads to tigecycline treatment failure. (Mus musculus) PubMed

 24630.

Both RNA-seq analysis and RT-qPCR results in Ligon-lintless-1 mutant and wild-type may provide strong evidence of LNC_001237, LNC_017085 and ghr-miR2950 being integral molecular elements participating in various pathways of cotton fiber development (Ligon-lintless-1,LNC_001237, LNC_017085). (Mus musculus) PubMed

 24631.

Argonaute (Ago) protein plays a central role in silencing gene expression by binding a "guide" strand to the base-pair with a complementary mRNA and degrading the mRNA. This work reveals novel roles for the core Ago domains and shows how the kinetic barriers that must be overcome for critical structural changes to occur lead to target repression/cleavage. [Argonaute] (Mus musculus) PubMed

 24632.

These data provide the first demonstration that Rgg/Shp signaling pathway comprises an active quorum sensing system in Streptococcus zooepidemicus.[Rgg/Shp] (Mus musculus) PubMed

 24633.

Nlegf-like encodes an integral membrane protein of 16,973 amino acid residues with 260 EGF-like repeats and 16 Ca(2+)-binding EGF repeats type (cbEGFs) in the extracellular portion. Nlegf-like was highly expressed in the integument and tended to peak at the middle stage or late stage of each nymph instar. Phylogenetic analysis showed this gene is conserved in many other insects.[egf-like] (Mus musculus) PubMed

 24634.

Overexpression of OsTPS8 was adequate to confer enhanced salinity tolerance without any yield penalty, suggesting its usefulness in rice genetic improvement.[OsTPS8] (Mus musculus) PubMed

 24635.

The findings of this study confirmed the prediction that the Multimerization Domain (MD) of SinR' is responsible for the interaction between SinR and SinR'. It was also discovered that SinR' regulates sporulation, toxin production and motility primarily by inhibiting SinR activity through the Multimerization Domain.[SinR, SinR'] (Mus musculus) PubMed

 24636.

The change in CsrA availability in response to nutrient availability allows V. cholerae to alter gene expression in response to environmental cues [CsrA]. (Mus musculus) PubMed

 24637.

Our data provide evidence that HSP101, a component of Plasmodium translocon of exported proteins, serves to unfold protein cargo requiring translocation [HSP101]. (Mus musculus) PubMed

 24638.

Rbp35 Rbp35 regulates expression and distal polyadenylation site selection of virulence and signalling-associated genes, tRNAs and transposable elements [Rbp35] (Mus musculus) PubMed

 24639.

the evolutionary aspect and pharmacological modulation of MRAP2 on MC4R signaling in Nile tilapia, was examined.[MRAP2, MC4R] (Mus musculus) PubMed

 24640.

the conserved histidyl residue of Prx6-type enzymes is non-essential for catalysis, PfPrx6 is rapidly oxidized by hydroperoxides, and the gain-of-function mutant PfPrx6(H39Y) might provide a valuable tool to address the influence of conformational changes on the reactivity of Prx6 homologues. (Mus musculus) PubMed

 24641.

In this study, a preliminary screening of cellular extracts of S. solfataricus allowed the identification of an alpha-N-acetylglucosaminidase activity. However, the characterization of the corresponding recombinant enzyme revealed a novel GlcNAc de-N-acetylase, which, in cooperation with the alpha-glucosidase, catalyzed the hydrolysis of O-alpha-GlcNAc glycosides. [GlcNAc De-N-Acetylase] (Mus musculus) PubMed

 24642.

A wide range of virulence regulatory functions are governed by Lon in Salmonella enterica ser. Typhimurium.[Lon] (Mus musculus) PubMed

 24643.

AGO18b strongly binds to miR166a-3p. The AGO18b-bound mRNA targets of miR166a-3p were obtained by cRIP-seq, and the molecular function of AGO18b in regulating spikelet meristems was confirmed (AGO18b). (Mus musculus) PubMed

 24644.

Using the parasite Plasmodium berghei and the mosquito Anopheles gambiae, the authors confirmed that sporozoite infection alters the host-seeking behaviour of mosquitoes by making them more likely to refeed after a first blood meal, and that apyrase activity is one of the mechanisms of the increased biting persistence and motivation of infectious mosquitoes.[apyrase] (Mus musculus) PubMed

 24645.

In summary, Salmonella typhimurium uses PbgA to influence lipopolysaccharide assembly during stress in order to survive, adapt, and proliferate within the host environment.[PbgA] (Mus musculus) PubMed

 24646.

The expression of histone deacetylase 1 and 8 was analyzed in different developmental stages and tissues, and in response to heat and cold (HDAC1, HDAC8). (Mus musculus) PubMed

 24647.

These findings demonstrate that the subcutaneous injection of Human parvovirus B19-VP1u or human bocavirus-VP1u proteins in OVA-sensitized mice result in elevated asthmatic indices and suggest that human parvoviruses may increase the risk of developing airway inflammation in a mouse model of asthma. [VP1 protein] (Mus musculus) PubMed

 24648.

TWI1 role in the patterning of bundle sheath, sclerenchyma and interveinal mesophyll cells.TWI1 encodes a transcription factor binding protein that interacts with OSH15.[TWI1] (Mus musculus) PubMed

 24649.

MscL allosteric activation is triggered by lipid-chain penetration into MscL nano-pockets.[MscL] (Mus musculus) PubMed

 24650.

CcrM contains an N-terminal methyltransferase domain and a C-terminal nonspecific DNA-binding domain. CcrM is a dimer, with each monomer contacting primarily one DNA strand: the methyltransferase domain of one molecule binds the target strand, recognizes the target sequence, and catalyzes methyl transfer, while the C-terminal domain of the second molecule binds the non-target strand.[Ccrm] (Mus musculus) PubMed

 24651.

Alkaline pectate lyase gene (pppel9a) from Paenibacillus polymyxa KF-1 was cloned and characterized. 449-residue protein belongs to the polysaccharide lyase family 9 (PL9). Substrate specificity of this protein is studied. (pectate lyase gene: pppel9a) (Mus musculus) PubMed

 24652.

Enzyme secretion is inhibited in A. niger by asexual reproduction. The sporulation protein FlbA is involved in this process by impacting the expression of 36 predicted transcription factor genes. Here, it is shown that one of these predicted transcriptional regulators, RpnR, regulates protein secretion and proteotoxic stress resistance.[rpnR] (Mus musculus) PubMed

 24653.

salmonellae carrying sseK1 and sseK3 employ the glycosyltransferase effectors to antagonise different components of death receptor signaling.[Ssek1, Ssek3] (Mus musculus) PubMed

 24654.

A novel eggshell-associated protein, NlChP38, containing an amelogenin domain, is essential for normal ovulation in Nilaparvata lugens. NlChP38 plays an important role in eggshell formation and could be a potential target for RNA interference control of N. lugens. (Mus musculus) PubMed

 24655.

These results suggest that AcMNPV-miR-3 may play a regulatory role in budded virions and occlusion-derived virions production. (Mus musculus) PubMed

 24656.

VeA is functionally involved in asexual cycle, stress tolerance and transcriptional regulation of B. bassiana [VeA]. (Mus musculus) PubMed

 24657.

Flagellin (Hag) is thought to be restricted at the level of translation by a partner-switching mechanism involving FliW and the homodimeric RNA-binding protein CsrA (CsrA(dimer)).[Hag, FliW, CsrA] (Mus musculus) PubMed

 24658.

These data present a new role for YpdA in S. aureus physiology and virulence through the bacillithiol system [YpdA]. (Mus musculus) PubMed

 24659.

AgrE is a hitherto unrecognized enzyme that contains both an N-terminal alpha/beta propeller domain and a unique C-terminal domain which showed arginine dihydrolase activity of the N-terminal domain and ornithine cyclodeaminase activity of the C-terminal domain [AgrE] (Mus musculus) PubMed

 24660.

having more than one non-neutral mutation in NS5a was associated with higher sustained virological response [NS5a] (Mus musculus) PubMed

 24661.

Casp8L inhibits the immune deficiency signaling pathway via forming amyloidal aggregates with DREDD [Casp8L] (Mus musculus) PubMed

 24662.

We confirmed a primary role in tyrosine import for ApiAT5-3. Conditional knockout of apiAT5-3 results in transcriptional upregulation of most ribosomal subunits, but no alternative transporters, and subsequent parasite death. [ApiAT5-3]. (Mus musculus) PubMed

 24663.

we provide deep mechanistic insight into the role of AphA and highlight how V. cholerae utilises this regulator for diverse purposes (Mus musculus) PubMed

 24664.

FtsZ makes distinct contributions to the regulation of polar growth and cell division. [FtsZ] (Mus musculus) PubMed

 24665.

this study provides evidence for the circINHA/miR-10a-5p/CTGF regulatory pathway in follicular GC apoptosis and provides novel insights into the role of circRNAs in the modulation of ovarian physiological functions. (Mus musculus) PubMed

 24666.

Our findings support a model in which LuxR/HapR bind proximally to RNA polymerase to drive transcription initiation at a subset of quorum-sensing genes in Vibrio species [LuxR]. (Mus musculus) PubMed

 24667.

anaTic22 functions as periplasmic holdase for OMPs in Anabaena sp. PCC 7120 [Tic22]. (Mus musculus) PubMed

 24668.

Our findings support a model in which LuxR/HapR bind proximally to RNA polymerase to drive transcription initiation at a subset of quorum-sensing genes in Vibrio species [LuxR]. (Mus musculus) PubMed

 24669.

We demonstrate that the toxin-antitoxin systems responsible for plasmid pINV stability in S. flexneri are governed by the activity of Lon protease [Lon]. (Mus musculus) PubMed

 24670.

E. faecium acquired the esp gene more frequently than E. faecalis (78.6% versus 46.2%). E. faecium exhibits high rates of antimicrobial resistance, esp gene acquisition and biofilm formation.[esp] (Mus musculus) PubMed

 24671.

E. faecium acquired the esp gene more frequently than E. faecalis (78.6% versus 46.2%). E. faecium exhibits high rates of antimicrobial resistance, esp gene acquisition and biofilm formation.[esp] (Mus musculus) PubMed

 24672.

This study reveals that the microtubule-associated protein ZmGLR plays a crucial role in cortical microtubule reorientation and maize leaf morphogenesis. [GLR] (Mus musculus) PubMed

 24673.

Taken together, these findings address the function of CsPH8 in citrus vacuolar acidification, confirm that CsPH8 plays a key role in the variation of citric acid content, and supported that the acid fluctuation influenced by drought, is at least partly due to the change of CsPH8 transcript level.[PH8] (Mus musculus) PubMed

 24674.

PbrPCCP1 and PbrTTS1 expression levels were consistently present in the style after pollination, and their expression levels were up-regulated within 24 h. This implied that they could co-regulate pollen tube growth when the pollen tube grew in the pistil.[PCCP1; TTS1] (Mus musculus) PubMed

 24675.

Results obtained in the present work suggest that BI-1 has a dual role in the regulation of programmed cell death during symbiosis, extending the understanding of its critical function in the modulation of host immunity while responding to beneficial microbes.[BI-1a] (Mus musculus) PubMed

 24676.

Description of a structural model of an alpha-type carbonic anhydrase (alpha-type carbonic anhydrase). (Mus musculus) PubMed

 24677.

Based on the authors' findings in flax, carinata, camelina, and Arabidopsis in this study, they suggest that co-suppression of FAD2 occurs widely in plants and therefore may present a common barrier to improving 18:2 content via bioengineering FAD2 expression.[FAD2] (Mus musculus) PubMed

 24678.

Emp12 is required for the trans-splicing of nad2 intron 2 and cis-splicing of nad2 introns 1 and 4, and is important to complex I biogenesis, and embryogenesis and endosperm development in maize.[EMP12] (Mus musculus) PubMed

 24679.

mice develop nonproductive immune responses against GP1 from Lassa virus, which is in contrast to the effective neutralizing responses that GP1 from Junin virus elicits. Thus, GP1 from Lassa virus is indeed an immunological decoy and GP1 from Junin virus may serve as a constituent of a future vaccine. (Mus musculus) PubMed

 24680.

this study might provide some understanding on the possible sigma(E)TF-DNA recognition prior to transcription initiated for the delta-endotoxins production.[sigma (E)TF] (Mus musculus) PubMed

 24681.

PtsF and PtsG form membrane embedded clusters that localize in a punctate pattern [PtsF; PtsG]. (Mus musculus) PubMed

 24682.

The ATP-binding activity of DndB stimulates the dissociation of the DndB-DNA complex, allowing transcriptional initiation, whereas its ATP hydrolysis activity promotes the conversion of DndB-ATP to free DndB that is capable of rebinding to promoter DNA for transcriptional inhibition. [DndB] (Mus musculus) PubMed

 24683.

(5-HT1A receptor) Chronic social defeat in adult female voles was mediated by the action of serotonin on the 5-HT1A receptors in pre-limbic cortex. (Mus musculus) PubMed

 24684.

PpUGT85A2 expression is a major control point predicting linalyl-beta-d-glucoside content.[UGT85A2] (Mus musculus) PubMed

 24685.

CnPpz1 is a functional Ser/Thr protein phosphatase; CnHal3a and CnHal3b are PPC decarboxylase enzymes [Ppz1; Hal3a; Hal3b] (Mus musculus) PubMed

 24686.

The major breakthrough of this work is that viral protein IE2 localizes and transactivates its own viral DNA through a most unlikely route, i.e., host proteins Daxx and H3.3, which are designed to efficiently restrict viral DNA from expression. (Mus musculus) PubMed

 24687.

In Aspergillus nidulans, absence of CrzA activity leads to alkaline pH sensitivity and loss of tolerance to high levels of extracellular calcium [CrzA]. (Mus musculus) PubMed

 24688.

Our results showed that FgAMA1 is dispensable for meiosis but important for ascospore formation and discharge [FgAMA1]. (Mus musculus) PubMed

 24689.

These results clearly demonstrate an important role of OsVIN2 as sink strength modulator that is critical for the maintenance of sucrose flux into developing seed grains.[OsVIN2] (Mus musculus) PubMed

 24690.

KpeA is a novel Zn(II)2-Cys6-type protein likely involved in conidiation and kojic acid production at the transcriptional level [KpeA]. (Mus musculus) PubMed

 24691.

We demonstrate that HU and Lsr2 interact to form a complex. This physical and functional interaction is likely to be important for DNA organization and gene expression in Mycobacterium tuberculosis and perhaps other bacterial species [HU; Lsr2]. (Mus musculus) PubMed

 24692.

The N-terminal and middle domains consist of tandem two-residue repeats of Gln-Ala and Gly-Ala, respectively, which are expected to fold into beta-strands and may further stack into beta-sheets, whereas the C-terminal domain contains multiple consecutive Gln residues.[LNSP1, LNSP2] (Mus musculus) PubMed

 24693.

Our results show that 14-3-3 is an important virulence factor in P. brasiliensis-induced pulmonary infection. [14-3-3] (Mus musculus) PubMed

 24694.

This is the first study validating that the miRNA PC-5P-12969, might be a potential biomarker for ischemic stroke.miRNA PC-5P-12969] (Mus musculus) PubMed

 24695.

Here, we identify CgoX as the enzyme performing the oxygen-dependent and -independent synthesis of coproporphyrin from coproporphyrinogen, in the coproporphyrin-dependent heme synthesis pathway [CgoX]. (Mus musculus) PubMed

 24696.

Data report a crystal structure of the Pho7 DNA-binding domain (DBD) bound at its target site 2 in the pho1 promoter.Mutagenesis of Pho7 amino acids at the DNA interface identified nucleobase contacts at the periphery of the footprint that are essential for the induction of pho1 expression in response to phosphate starvation and for Pho7 binding to site 1 in the pho1 promoter. [Pho7] (Mus musculus) PubMed

 24697.

localization at telomeres significantly different between D. simulans and D. melanogaster, reflecting the rapid evolution of telomeric retrotransposon copy number composition between the two species [gfzf] (Mus musculus) PubMed

 24698.

Here, we show that beta-lactam antibiotics induce sigma(P) activation by degradation of the anti-sigma factor RsiP [RsiP]. (Mus musculus) PubMed

 24699.

protein phosphatases TbTim50 and PIP39 cross talk via the AMPK pathway and modulate cellular metabolic activities under stress [TbTim50; PIP39] (Mus musculus) PubMed

 24700.

In T. brucei, Cytidine deaminase (CDA) is uniquely involved in providing dUMP. Furthermore, we report the mitochondrial localization of CDA [Cytidine deaminase]. (Mus musculus) PubMed

 24701.

Theexpression level of PTEN was significantly downregulated and that of miR-374b tended to be upregulated in recurrent Canine oral malignant melanoma tissues after radiation therapy compared with the pre-treatment tissues. [miR-374b] (Mus musculus) PubMed

 24702.

The ability of leptospiral haemolysin rSph2 to cause apoptosis likely contributes to the pathogenesis of leptospirosis.[Sph2] (Mus musculus) PubMed

 24703.

Therefore, AveI functions as a global regulator in Streptomyces avermitilis, controls not only secondary metabolism and morphological differentiation, but also primary metabolism.[AveI] (Mus musculus) PubMed

 24704.

IL-1R8 was down-regulated in epithelial mammary cells following S. aureus infection. [IL-1R8] (Mus musculus) PubMed

 24705.

Taken together, these findings add new insights into the biological function of teleost MHC Ialpha and emphasize the importance of MHC I gene products for the control of E. tarda infection. [MHC Ialpha] (Mus musculus) PubMed

 24706.

increases the GTPase activity of MglA by reorientation of key catalytic residues of MglA combined with allosteric regulation of nucleotide exchange by the Ct-helix; regulation essential for cell polarity in motility [MglB, mutual gliding motility B] (Mus musculus) PubMed

 24707.

These results suggest that TgZnT transports Zn(2+) into the plant-like vacuole and plays an important role in the Zn(2+) tolerance of T. gondii extracellular tachyzoites [TgZnT]. (Mus musculus) PubMed

 24708.

Ron2 knockdown sporozoites were severely impaired in their ability to invade salivary glands, via decreasing the attachment capacity to the substrate.[RON2] (Mus musculus) PubMed

 24709.

TcpA acted as a new virulence factor in Y. ruckeri could suppress innate immune response and increase virulence by inhibiting TLR and MyD88-mediated specific signaling, highlighting a novel strategy for innate immune evasion in bacteria.[TcpA] (Mus musculus) PubMed

 24710.

The QseC directly regulates Locus of Enterocyte Effacement as well as virulence mechanisms.[QseC] (Mus musculus) PubMed

 24711.

Yr82 interacted with Yr29 to produce lower stripe rust responses at the adult plant stage. [Yr82] (Mus musculus) PubMed

 24712.

Two stem rust resistance genes, Sr883-6A gene and the recessive gene Sr883-2B, were identified on chromosome arms 2BL and 6AL of the cultivated emmer wheat accession PI 193883 [Sr883-6A; Sr883-2B] (Mus musculus) PubMed

 24713.

This study is the first functional characterization of HutZ in a fish pathogen, and these findings suggested that HutZEp is essential for E. piscicida biofilm formation and contributes to host infection.[HutZ] (Mus musculus) PubMed

 24714.

Vigun10g019300 encodes NAD-dependent malic enzyme 1 (NAD-ME1), while Vigun10g019400 encodes for dynamin-related protein 1C (DRP1C), and are associated with resistance to Cercospora leaf spot disease [Vigun10g019300; Vigun10g019400] (Mus musculus) PubMed

 24715.

HupY, a protein with no known heme binding domains, represents a novel heme binding protein playing an important role in bacterial iron homeostasis as well as vaginal colonization [hupY]. (Mus musculus) PubMed

 24716.

We identified two new components of the transport machinery that constructs this complex cell wall. These two accessory proteins are in a complex with the MmpL3 transporter. One of these proteins, TtfA, is required for mycolic acid transport and cell viability [TtfA]. (Mus musculus) PubMed

 24717.

We identified two new components of the transport machinery that constructs this complex cell wall. These two accessory proteins are in a complex with the MmpL3 transporter. One of these proteins, TtfA, is required for mycolic acid transport and cell viability [TtfA]. (Mus musculus) PubMed

 24718.

Hansenula polymorpha, lacking the peroxisome fission protein Pex11, still show peroxisome fission and inheritance. Also, in cells of mutants without the peroxisome inheritance protein Inp2 peroxisome segregation can still occur. In contrast, peroxisome fission and inheritance were not observed in cells of a pex11 inp2 double deletion strain. (2 genes: pex11, inp2) (Mus musculus) PubMed

 24719.

The results suggest that LvCrustinB plays an important role in innate immunity and may be potentially utilized as antibacterial agents in shrimp.[CrustinB] (Mus musculus) PubMed

 24720.

The findings provide new insights into the mechanism of the MdPOB1 modulation of apple ring rot resistance, which occur by directly regulating potential downstream target protein MdPUB29 for proteasomal degradation in apple. (Mus musculus) PubMed

 24721.

These results suggest the existence of an integrin-beta1 - and CEACAM1- or CEACAM5-dependent type IV secretion system delivery pathway for Helicobacter pylori CagA, which is clearly independent of VacA.[CagA] (Mus musculus) PubMed

 24722.

VraSR deletion mutant (DeltavraSR) of vancomycin-intermediate Staphylococcus aureus (VISA) Mu3 is more susceptible to phagocytosis by polymorphonuclear leukocytes (PMNs) with reduced ability to survive in PMNs. DeltavraSR mutant shows thinner cell wall, reduced adhesion, and decreased biofilm-forming ability. The transcript levels of cell wall synthesis-related genes and adhesion-associated genes are decreased in the m... (Mus musculus) PubMed

 24723.

The adaptive proline response is independent from PfeIK1 and eIF2alpha signaling.[PfeIK1] (Mus musculus) PubMed

 24724.

Enhanced Senescence Process is the Major Factor Stopping Spike Differentiation of Wheat Mutant ptsd1. (Mus musculus) PubMed

 24725.

AhR/ARNT regulate the expression of CYP6CY3 and CYP6CY4 cooperatively, conferring the nicotine adaption of M. persicae nicotianae to tobacco. [AhR, ARNT, CYP6CY3, CYP6CY4] (Mus musculus) PubMed

 24726.

subset of temperature-responsive genes dependent on MSB2 for its expression, implicating these genes in the process of filamentation [MSB2] (Mus musculus) PubMed

 24727.

Data support the proposal that Slp directly contributes to initial adherence, with the pIgR protein as its proposed receptor. [Slp] (Mus musculus) PubMed

 24728.

OsFLU1 is an important regulator of chlorophyll biosynthesis in rice. (Mus musculus) PubMed

 24729.

mapping of a silique length- and seed weight-related gene BnSLA09 [BnSLA09] (Mus musculus) PubMed

 24730.

The evolution of pomc, pmch and pmchl genes and acquisition of hormonal status for MCHL explain different mechanisms used by vertebrates to background-adapt.[pmchl] (Mus musculus) PubMed

 24731.

Study found that Asc1 directly binds and stabilizes the interaction between small ribosomal protein Rps0A/uS2 and eukaryotic initiation factor 3a. In the absence of Asc1, the interaction between eIF3a and Rps0A/uS2 was compromised.[Asc1] (Mus musculus) PubMed

 24732.

the parasite rhoptry protein ROP17 is necessary for export of dense granule effector proteins [ROP17]. (Mus musculus) PubMed

 24733.

Study shows that all tested P. falciparum isolates contain an inactivating mutation in an erythrocyte invasion associated gene, PfEBA165, the homologues of which are intact in all ape-infective Laverania species and suggests that inactivation of PfEBA165 may have been important in the emergence of P. falciparum as a human pathogen. (Mus musculus) PubMed

 24734.

Study of type IVa competence pilus of Vibrio cholerae as a model system shows that the ATPase activity of PilU is critical for pilus retraction in PilT Walker A and/or Walker B mutants. PilU does not, however, contribute to pilus retraction in DeltapilT strains. Thus, these data suggest that PilU is a bona fide retraction ATPase that supports pilus retraction in a PilT-dependent manner.[PilU, homolog of PilT] (Mus musculus) PubMed

 24735.

These results show a specific role for Ret51 in pioneer axon growth, and suggest a critical role for long-range retrograde Ret signaling in regulating growth cone dynamics through downstream transcriptional changes.[Ret51] (Mus musculus) PubMed

 24736.

CalY is, a bifunctional protein, which switches from a cell-surface adhesin activity in early stationary phase, to the production of fibers in mid-stationary phase and in biofilms [CalY]. (Mus musculus) PubMed

 24737.

Pi56(t) Among tested markers, two markers (RM7364 and pi21_79-3) corresponding to the blast resistance genes (Pi56(t) and pi21) were significantly associated and explained a phenotypic variance of 4.9 to 5.1% with the blast resistance (Pi56(t)). (Mus musculus) PubMed

 24738.

These results are consistent with a model in which phosphorylation of IreK at distinct sites reciprocally regulates IreK activity in vivo to promote adaptation to cell wall stresses.[IreK] (Mus musculus) PubMed

 24739.

viral PA and host ANP32A are crucial for the emergence of PB2 E627K during adaptation of H7N9 to humans. [PA] (Mus musculus) PubMed

 24740.

HipT is a kinase that phosphorylates tryptophanyl-tRNA synthetase and thereby inhibits translation and induces the stringent response [HipT] (Mus musculus) PubMed

 24741.

coregulates CSD1 and ADH1 mRNAs in response to water deficit - [miR398 and miR2119] (Mus musculus) PubMed

 24742.

Rice black-streaked dwarf virus major outer capsid protein (also known as P10) suppresses the protein kinase C activity of small brown planthopper Laodelphax striatellus through interacting with the insect's receptor for activated protein kinase C 1 ( P10). (Mus musculus) PubMed

 24743.

Pizh-1 may function as the executor nucleotide-binding leucine-rich repeat (NLR) and Pizh-2 as a 'helper' NLR that shares functional redundancy with other NLRs. The current study provides not only a good tool for rice disease resistance breeding but also deep insight into NLR association and function in plant immunity. [Pizh-1;Pizh-2] (Mus musculus) PubMed

 24744.

VdmilR1 targets a hypothetical protein-coding gene, VdHy1, at the 3'UTR for transcriptional repression through increased histone H3K9 methylation of VdHy1. Pathogenicity analysis reveals that VdHy1 is essential for fungal virulence.[Hy1] (Mus musculus) PubMed

 24745.

Bsp9 may suppress plant immune signalling by interfering with the interaction between host-plant WRKY33 and a central regulator in the MAPK cascade. [Bsp9] (Mus musculus) PubMed

 24746.

interacts with and phosphorylates TaNH2 to activate defense responses to stripe rust - [CIPK10] (Mus musculus) PubMed

 24747.

QnrB increases the bacterial mutation rate and induces DNA replication stress [QnrB] (Mus musculus) PubMed

 24748.

Roles of Polycomb group proteins Enhancer of zeste (E(z)) and Polycomb (Pc) during metamorphosis and larval leg regeneration in the flour beetle Tribolium castaneum. (Mus musculus) PubMed

 24749.

participates in the synthesis of apigenin, conferring protection against UV-B radiation [FNSI and FNSII] (Mus musculus) PubMed

 24750.

Biochemical and genetic studies reveal that HtrA, a serine protease of B. burgdorferi, controls FlaB protein turnover [HtrA]. (Mus musculus) PubMed

 24751.

These data indicate that the amino acid residue V26 of EMCV 2C plays important roles in inhibiting type I IFN production by interacting with MDA5 [2C protein]. (Mus musculus) PubMed

 24752.

C-signaling activates FruA at least ninefold posttranslationally in order to commit a cell to spore formation. [FruA] (Mus musculus) PubMed

 24753.

results highlight the predominant role of Ha-ROXL in regulating axillary meristems in sunflower (Ha-ROXL) (Mus musculus) PubMed

 24754.

The structures revealed that Ca(2+) binds to the loop that forms the upper wall of the ligand-binding pocket. Isothermal titration calorimetry (ITC) measurements indicated that Ca(2+) changes the ligand binding affinity of Mlp24p. Furthermore, Ca(2+) affected chemotactic behaviors to various amino acids mediated by Mlp24.[Mlp24] (Mus musculus) PubMed

 24755.

The results of this study help to elucidate the genetic and molecular bases of Ghd8 and Ghd7 interactions, indicating that Ghd8 acts upstream of Ghd7 to activate its transcription, which inhibits Hd3a expression and thus affects flowering time and rice adaptation. [GHD8] (Mus musculus) PubMed

 24756.

key enzyme in the biosynthesis of cuticular wax {KCS6} (Mus musculus) PubMed

 24757.

Resistance to azithromycin is encoded in the gene mph(A) [ mph(A)]. (Mus musculus) PubMed

 24758.

Transcriptome analysis of the Staphylococcus aureus UAMS-1, UAMS-1 Deltanor, and UAMS-1 Deltanos strains under NO stress and anaerobic growth demonstrates that Nor contributes to nucleotide metabolism and Nos to glycolysis.[Nor, Nos] (Mus musculus) PubMed

 24759.

The primary redox partners of SdbA that maintain its active site in an oxidized state are a surface-exposed thioredoxin family lipoprotein called SdbB (Sgo_1171) and an integral membrane protein annotated as CcdA2. Inactivation of sdbB and ccdA2 simultaneously, but not individually, recapitulated the sdbA mutant phenotype.[SdbA, SdbB, CcdA2] (Mus musculus) PubMed

 24760.

Calcineurin responsive zinc finger-1 (CRZ-1) binds to a unique sequence in the ncs-1 promoter, causing upregulation of NCS-1 that binds to MID-1 for tolerance to Ca(2+) stress [CRZ-1]. (Mus musculus) PubMed

 24761.

Inactivation of vfmI decreased the production of zeamines and cell wall degrading enzymes. VfmH directly interacte with the promoters of vfmA, vfmE and vfmF, and significantly reduces the production of Vfm quorum sensing signal. [VfmI; VfmH] (Mus musculus) PubMed

 24762.

modulates response to salt and drought - [PLC4] (Mus musculus) PubMed

 24763.

This study solved ten structures of the Escherichia coli rhomboid protease GlpG in a bicelle membrane undergoing time-resolved steps that encompass the entire proteolytic reaction on a transmembrane substrate and an aldehyde inhibitor. [rhomboid protease GlpG] (Mus musculus) PubMed

 24764.

This study uses biochemical and cryoelectron microscopy analyses to show that the amino-terminal amphipathic helix of SecA and the ribosomal protein uL23 form a composite binding site for the transmembrane domain (TMD) on the nascent protein. [SecA] (Mus musculus) PubMed

 24765.

This study shows the complete structure of the flagellar hook protein from Salmonella enterica in its supercoiled 'curved' state, at 2.9 A resolution. [flagellar hook] (Mus musculus) PubMed

 24766.

We observed the localization of one secreted protein, Mpt64, to the endoplasmic reticulum (ER) during M. tuberculosis infection of macrophages [Mpt64]. (Mus musculus) PubMed

 24767.

TaHOS15 functions in a histone deacetylase complex with TaHDA6 to fine-tune the defense response to Bgt in common wheat.[HOS15,HDA6] (Mus musculus) PubMed

 24768.

hydroxyproline O-arabinosyltransferase localized to the Golgi; gene responsible for hypernodulation mutant [plenty] (Mus musculus) PubMed

 24769.

This implies that formation of the TEP1cut/LRIM1/APL1C complex is related to the conformational change that induces the precipitation of cleaved TEP1.[TEP1, LRIM1] (Mus musculus) PubMed

 24770.

The structures reveal that the complex of Las1 RNase and the Grc3 polynucleotide kinase (PNK) adopts a butterfly-like architecture, harboring a composite HEPN nuclease active site flanked by discrete RNA kinase sites. (Mus musculus) PubMed

 24771.

Pellicle biogenesis in S. oneidensis is controlled by a complex pathway that involves the chemotaxis response regulator CheY3, the two putative diguanylate cyclases PdgA and PdgB, and the c-di-GMP binding protein MxdA. [PdgA, PdgB, CheY] (Mus musculus) PubMed

 24772.

By combining three complimentary approaches, the authors identify the host protein G3BP1 as a critical host factor required for norovirus VPg-dependent translation, identifying a new role for G3BP1 in virus-specific translation.[VPg] (Mus musculus) PubMed

 24773.

Collectively, these data from mutational and overexpression analyses of the APS biosynthesis genes and in vitro enzymatic assays indicate that Uxe functions as UDP-xylose 4- and UDP-glucose 4-epimerase catalyzing UDP-xylose/UDP-arabinose and UDP-glucose/UDP-galactose interconversions, respectively.[Uxe] (Mus musculus) PubMed

 24774.

This study evaluated the response of yeast to the loss of a single copy of ARH1, an oxidoreductase of the mitochondrial inner membrane, which is among the few mitochondrial proteins that is essential for viability in yeast.[Arh1p] (Mus musculus) PubMed

 24775.

Here, the authors describe a paralogous sensor duo, ScuR and SarF, which circumvents ComR in order to disconnect DNA transformation competence and bacteriocin-mediated predation.[ScuR, SarF] (Mus musculus) PubMed

 24776.

FlgZ impairs swimming and swarming motility in P. aeruginosa. (Mus musculus) PubMed

 24777.

Overexpression of FT2 in Brachypodium distachyon and barley results in precocious flowering and reduced spikelet number, while down-regulation by RNA interference results in delayed flowering and a reduced percentage of filled florets. Similarly, truncation mutations of FT2 homeologs in tetraploid wheat delayed flowering (2-4 d) and reduced fertility. [FT2] (Mus musculus) PubMed

 24778.

TIFY9 is intimately involved in salicylic acid-mediated resistance to grape powdery mildew. (gene: TIFY9) (Mus musculus) PubMed

 24779.

Overexpression of FT2 in Brachypodium distachyon and barley results in precocious flowering and reduced spikelet number, while down-regulation by RNA interference results in delayed flowering and a reduced percentage of filled florets. Similarly, truncation mutations of FT2 homeologs in tetraploid wheat delayed flowering (2-4 d) and reduced fertility. [FT2] (Mus musculus) PubMed

 24780.

NarJ serves as a chaperone for both the anaerobic respiratory nitrate reductase NarG and the assimilatory nitrate reductase NasC [NarJ] (Mus musculus) PubMed

 24781.

We show that centromere translocation can be inhibited by an evolutionarily conserved pole-localized protein that we have named SpbR [SpbR]. (Mus musculus) PubMed

 24782.

Low genetic diversity was observed in the erythrocyte-binding protein of Malaysia Borneo compared to Peninsular Malaysia. The erythrocyte-binding protein was found to be under strong purifying selection to retain infectivity in monkeys and it plays a limited role in the zoonotic potential of P. knowlesi (erythrocyte-binding protein). (Mus musculus) PubMed

 24783.

Three mutations in ATPase subunit 6 were identified and their cosegregation with male sterility was established using tobacco male sterile hybrids and Nicotiana suvaolensis. (Mitochondrial ATP synthase). (Mus musculus) PubMed

 24784.

After growing for 15 days on media containing 0.2mM nitrate concentration, wild-type plants became yellowor died, while the transgenic MeNRT2.1 Arabidopsis plants maintained normal growth. These results demonstrate that MeNRT2.1 has an important role in adaptation to low nitrate concentration as a nitrate transporter. (MeNRT2.1) (Mus musculus) PubMed

 24785.

microRNA-92a regulates the expression of aphid bacteriocyte-specific secreted protein 1 (SP1). [SP1]; [miR-92a] (Mus musculus) PubMed

 24786.

This study investigates how the small RNA ArcZ regulates motility at the transcriptional level and identifies the transcription factor Lrp as a novel participant in the regulation of several virulence-associated traits [Lrp]. (Mus musculus) PubMed

 24787.

Prolyl aminodipeptidase structure reveals substrate binding site with cysteine and a calcium-binding motif with the consensus sequence DX(DN)XDG (Prolyl aminodipeptidase). (Mus musculus) PubMed

 24788.

The ClpXP machinery is a two-component protease complex that performs targeted protein degradation in bacteria. This study unravels the heptamer-hexamer binding interface and provide novel insight into the ClpX-ClpP cross-talk and activation mechanism. [ClpX, ClpP] (Mus musculus) PubMed

 24789.

PavA crystal structure reveals that each monomer of the dimeric protein consists of two domains (domains I and II) and a short alpha-helix (alpha6) at the C-terminus that are connected by elongated loops.[PavA] (Mus musculus) PubMed

 24790.

In low-iron environments, cyanobacteria express IsiA, a photosystem I antenna, critical to their survival. This study presents the structure of the photosystem I-IsiA complex isolated from the mesophilic cyanobacterium Synechocystis sp. PCC 6803. [IsiA] (Mus musculus) PubMed

 24791.

the regulation and signal transduction mechanism of insulin on leptin mRNA levels in the goldfish liver, is reported.[leptin] (Mus musculus) PubMed

 24792.

The overexpression of lncRNAs NR024118 decreased NFkappa B expression levels and activated the Nrf2 signaling pathways in lipopolysaccharide induced ATDC5 chondrocytes. [lncRNAs NR024118] (Mus musculus) PubMed

 24793.

Mutation of msaABCR resulted in reduced production of SarA and a reduced capacity to form a biofilm in both strains.[SarA, msaABCR] (Mus musculus) PubMed

 24794.

Transformation of MaSPL16 in banana fruits led to enhanced transcript levels of MaLCYB1.1 and MaLCYB1.2 and hence the total carotenoid accumulation. [MaSPL16,MaLCYB1.1, MaLCYB1.2] (Mus musculus) PubMed

 24795.

The S4 helix of a sea urchin HCN channel undergoes a substantial (~10 A) downward movement in response to membrane hyperpolarization. The carboxy-terminal part of the S4 helix exhibits an unexpected tilting motion during hyperpolarization activation. HCN. (Mus musculus) PubMed

 24796.

In this study, we report the importance of two nutrient-sensing bacterial regulators, named (p)ppGpp and CodY, for the ability of E. faecalis to infect the catheterized bladder of mice [(p)ppGpp]. (Mus musculus) PubMed

 24797.

This study presents structural snapshots, as determined by X-ray crystallography and cryo-electron microscopy, of actively initiating influenza polymerase, which comprises subunits PA, PB1 and PB2, as it transitions towards processive elongation. [PA, PB1, PB2] (Mus musculus) PubMed

 24798.

These results indicate that the cydAB operon, being regulated by FexA, plays a crucial role in V. vulnificus survival under redox-fluctuating in vivo conditions. [FexA] (Mus musculus) PubMed

 24799.

Results found that a null AcrB Escherichia coli strain developed an extremely high-level of resistance to chloramphenicol, cross resistance to quinolones and erythromycin. [AcrB] (Mus musculus) PubMed

 24800.

The nuclear export of ribosomal subunits (60S and 40S) depends in part on the activity of the essential auxiliary export receptors TbMtr2 and TbMex67 [TbMtr2; TbMex67]. (Mus musculus) PubMed

 24801.

ATP binding causes SecY to open and SecA to close; while, ADP produced by hydrolysis, has the opposite effect.[SecA, SecY] (Mus musculus) PubMed

 24802.

The high-level of echinocandin resistance in the clinical isolate of C. glabrata L74 was concluded to result from the combination of null function of Fks1 and the point mutation E655K in Fks2. [FKS1, FKS2] (Mus musculus) PubMed

 24803.

Pyruvate kinase I (pykF) gene was predicted to be a chief target gene of Vvrr1 involved in virulence regulation.[Vvrr1] (Mus musculus) PubMed

 24804.

Here the authors report on a terpene synthase (DdTPS8)-cytochrome P450 (CYP521A1) gene cluster that produces a novel C12 trisnorsesquiterpene and affects the development of Dictyostelium discoideum. DdTPS8 catalyzes the formation of a sesquiterpene discoidol and CYP521A1 catalyzes the conversion of discoidol to a novel trisnorsesquiterpene named discodiene.[DdTPS8] (Mus musculus) PubMed

 24805.

Therapeutic effects of vaccine derived from amastigote surface protein-2 (ASP-2) against Chagas disease in mouse liver. (Mus musculus) PubMed

 24806.

In this work, we identify heat shock protein 48 (HSP48) as a chaperone that is induced during development [HSP48]. (Mus musculus) PubMed

 24807.

Here, we show the role of the signaling mucin MsbA in the pathogen A. fumigatus, as a core sensor for cell wall morphogenesis, fungal growth, and virulence [MsbA]. (Mus musculus) PubMed

 24808.

miR-26b suppresses osteoblast differentiation of MC3T3-E1 cells via directly targeting ER-alpha. (Mus musculus) PubMed

 24809.

This study sequenced OmpA from cattle throughout Ghana naturally infected with A. marginale in order to determine the degree of variation in this gene in an area of suspected high genetic diversity. Three unique Ghanaian OmpA variants were identified. [OmpA] (Mus musculus) PubMed

 24810.

Here we show that the sensory domains of BifA and SagS are functionally interchangeable and that they use a similar mechanism of signal sensing and transduction [SagS]. (Mus musculus) PubMed

 24811.

Deletions of photosystem II assembly factors Ycf48, Ycf39 and Pam68 result in progressive loss of autotrophy. [Ycf48, Ycf39, Pam68] (Mus musculus) PubMed

 24812.

Here we show that TbMex67-TbMtr2 interact with members of the 60S ribosomal subunit 5S ribonuclear particle [TbMex67; TbMtr2]. (Mus musculus) PubMed

 24813.

Our results suggest that SAPP1 and SAPP2, but not SAPP3, influence host evasion by regulating cell damage, phagocytosis, phagosome-lysosome maturation, killing, and cytokine secretion [SAPP1; SAPP2; SAPP3]. (Mus musculus) PubMed

 24814.

TET1-mediated hydroxymethylation licences differentiated ductal cells to initiate organoids and activate the regenerative program through the transcriptional regulation of stem-cell genes and regenerative pathways including the YAP-Hippo signaling.[Hippo protein] (Mus musculus) PubMed

 24815.

CspA and CspC are essential for C. perfringens spore germination through activating SleC.[CspA, CspC, SleC] (Mus musculus) PubMed

 24816.

data suggest that PilM is a coupling protein that physically and functionally connects the soluble motor ATPase PilF to the DNA translocator via the PilMNO assembly platform [pilF] (Mus musculus) PubMed

 24817.

During catalysis, cytochrome P450cam undergoes significant conformational changes upon binding its substrate and redox partner, putidaredoxin (Pdx) : [cytochrome P450cam and putidaredoxin] (Mus musculus) PubMed

 24818.

Here we demonstrate that PPV nonstructural protein 1 (NS1) can induce host cell apoptosis and death [NS1]. (Mus musculus) PubMed

 24819.

This study shows that an RNAi-based approach to host-induced gene suppression (HIGS) of NAT1 could moderate deoxynivalenol levels in spring wheat. (Mus musculus) PubMed

 24820.

Orn exhibits exquisite substrate preference for diribonucleotides.[Orn] (Mus musculus) PubMed

 24821.

These data provide insights into the distinctive functions of VdSsk2 and VdSte11 in pathogenicity, stress adaptation, and microsclerotial formation in V. dahlia [VdSsk2; VdSte11 ]. (Mus musculus) PubMed

 24822.

This study suggests that lsr operon plays a role in the pathogenesis of APEC. (Mus musculus) PubMed

 24823.

a near-atomic model of the Ctf3 complex, the outermost Ctf19c sub-assembly, is report.[Ctf3] (Mus musculus) PubMed

 24824.

Deletion of areB has significant phenotypic effects on the utilization of specific carbon sources. [ areB ] (Mus musculus) PubMed

 24825.

the high amount of VvK3.1 transcripts detected in the pulvinus strongly suggests a role for this Shaker in the swelling and shrinking of motor cells involved in paraheliotropic leaf movements.[Vvk3.1] (Mus musculus) PubMed

 24826.

ABCC3 gene expression and role in seed development.[ABCC3] (Mus musculus) PubMed

 24827.

OsHOP2 may serve as a global regulator to coordinate homologous pairing, synapsis and meiotic recombination in rice meiosis.[OsHOP2] (Mus musculus) PubMed

 24828.

ESA1 is located near the centromere of chromosome 1.ESA1 is involved in female gamete abortion during early mitosis.ESA1 encodes a nuclear-membrane localized protein containing an ARM repeat domain. [ESA1] (Mus musculus) PubMed

 24829.

CRA2 pathway acts independently from shoots to regulate nodule numbers.CRA2 regulates antagonistically lateral root formation and symbiotic nodule formation.[CRA2] (Mus musculus) PubMed

 24830.

Interaction with the host plant BSL family proteins Is essential for AVR2 virulence function.[AVR2] (Mus musculus) PubMed

 24831.

UBP15 as a positive regulator of grain width and size in rice.[UBP15] (Mus musculus) PubMed

 24832.

The findings revealed that miR-506 could be an important modulator of apoptosis and inflammation and a regulator of lung fibrosis.[mir-506] (Mus musculus) PubMed

 24833.

the role of the various methionine residues in the Escherichia coli CusB adapter protein [CusB] (Mus musculus) PubMed

 24834.

[NRT1.1B] the overexpression of NRT1.1B in rice significantly promoted SeMet translocation from roots to shoots, resulting in increased Se concentrations in shoots and rice grains (Mus musculus) PubMed

 24835.

7''-phosphotransferase-Ia [APH(7'')-Ia] The APH(7'')-Ia and aminoglycoside 4-phosphotransferase-Ia [APH(4)-Ia] from Escherichia coli structures fit globally when the structures are superposed at three catalytically important conserved residues, His, Asp and Asn, in the Brenner motif, which is conserved in aminoglycoside phosphotransferases as well as in eukaryotic protein kinases. (Mus musculus) PubMed

 24836.

By regulating the availability of the branching effectors TPX2, augmin and gamma-TuRC, combined with single-molecule observations, we show that first TPX2 is deposited on pre-existing microtubules (MTs), followed by binding of augmin/gamma-TuRC to result in the nucleation of branched MTs. (Mus musculus) PubMed

 24837.

The yields of alkaline serine protease (Asp), the exotoxin in Vibrio alginolyticus was dependent on both LuxR and VqsA in growth phase dependent manner. [Asp, VqsA] (Mus musculus) PubMed

 24838.

GhMYB212 functions as the main regulator of fiber elongation.[GhMYB 212] (Mus musculus) PubMed

 24839.

[fon4] the fon4 mutants produced a variable number of multi-floret spikelet, indicating that the mutation of different nucleotides in FON4 results in variable effects on its ability to control the spikelet determinacy, thereby producing more and less multi-floret spikelet. (Mus musculus) PubMed

 24840.

The Mars1 kinase (mutant affected in chloroplast-to-nucleus retrograde signaling1) confers photoprotection through signaling in the chloroplast unfolded protein response. [Mars1] (Mus musculus) PubMed

 24841.

Characterization of the structure of the full-length Nsp13 helicase of SARS-CoV (SARS-Nsp13) and investigation of the structural coordination of its five domains and how these contribute to its translocation and unwinding activity (Nsp13). (Mus musculus) PubMed

 24842.

Broad-Complex Z4 (BR-C Z4) was up-regulated by 20-hydroxyecdysone just before pupation, while transcription factor FoxJ and CHSA-2b were up-regulated during the pupal stage. [FoxJ] (Mus musculus) PubMed

 24843.

identification of the sequence motifs that contribute to the recognition of the target by the A. boonei casposase (casposase). (Mus musculus) PubMed

 24844.

5 Glycoside Hydrolase First Endo-Mannanase (RfGH5_7) Thin-layer chromatography analysis revealed that RfGH5_7 hydrolysed locust bean galactomannan predominantly to mannose, mannobiose, mannotriose and higher degree of polymerization of manno-oligosaccharides indicating an endo-acting catalytic mechanism. (Mus musculus) PubMed

 24845.

RpfF positively regulates biofilm formation and virulence and beta-lactamase induction, [RpfF] (Mus musculus) PubMed

 24846.

the occurrence of amphistomaty in P. trichocarpa involves PtSPCH1 and reflects selection for supporting rapid growth over investment in immunity.[PtSPCH1] (Mus musculus) PubMed

 24847.

The inducible transcription factor TaWRKY40 could activate the transcription of the TaGAPC1 gene, thereby increasing the tolerance of plants to drought stress (GAPC1). (Mus musculus) PubMed

 24848.

BmSPI51 is expressed exclusively in the silk glands during the larval fifth instar stage and is subsequently secreted into cocoon silk. Moreover, at a molar ratio of 1:1, BmSPI51 produced via prokaryotic expression exhibited inhibitory activity against trypsin and also proved to be highly stable over wide ranges of temperature and pH values.[SPI51] (Mus musculus) PubMed

 24849.

PiSFI3 is a 'WY-domain' RXLR effector that forms a novel trans-homodimer which is required for its ability to suppress pattern-triggered immunity via interaction with the U-box-kinase protein StUBK.[StUBK] (Mus musculus) PubMed

 24850.

PiSFI3 is a 'WY-domain' RXLR effector that forms a novel trans-homodimer which is required for its ability to suppress pattern-triggered immunity via interaction with the U-box-kinase protein StUBK.[PiSFI3] (Mus musculus) PubMed

 24851.

These findings provide new insights into the regulatory network of leaf senescence through the functional interactions among abscissic acid, MdbHLH93 and MdBT2.[MdbHLH93, MdBT2] (Mus musculus) PubMed

 24852.

PsAvh238 suppresses Type2 ACS-catalyzed ethylene biosynthesis and facilitates Phytophthora infection.[PsAvh238] (Mus musculus) PubMed

 24853.

rnTrpL base-pairs with trpD and destabilizes the polycistronic trpDC mRNA, indicating rnTrpL-mediated downregulation of the trpDC operon in trans (rnTrpL). (Mus musculus) PubMed

 24854.

DNA damage caused by HLHT stress induces ROS accumulation, which causes the injury and apoptosis of leaf cells in the ls1 mutant.[ls1] (Mus musculus) PubMed

 24855.

the transcriptional silencing of biosynthetic clusters by Lsr2 may protect Streptomyces from the inappropriate expression of specialized metabolites.[Lsr2] (Mus musculus) PubMed

 24856.

the determinants of grip by measuring how substrate tail sequences alter the unfolding activity of the unfoldase-protease ClpXP, is reported.[ClpXP] (Mus musculus) PubMed

 24857.

Overall, our study represents the first report of type 2 glycosyltransferase function in M. oryzae infection-related morphogenesis and pathogenesis [GT2]. (Mus musculus) PubMed

 24858.

The importance of this study is in highlighting that LeishIF4E-3 is essential for completion of the parasite life cycle [IF4E-3]. (Mus musculus) PubMed

 24859.

Tsn1(Tan spot necrosis1) expression and role in the Parastagonospora nodorum wheat infection. (Mus musculus) PubMed

 24860.

Disruption of Ser2 resulted in dominant heritable male sterility. Wild-type females mated with Ser2-deficient males laid eggs normally, but the eggs did not hatch. The authors detected no differences in other reproductive behaviors in the mutant males. These results support the conclusion that Ser2 gene is necessary for male reproductive success in diverse lepidopterans (Ser2). (Mus musculus) PubMed

 24861.

VirD5 interacts with the conserved mitotic Aurora kinase Ipl1 in yeast and likewise with plant Aurora kinases.[Ipl1] (Mus musculus) PubMed

 24862.

Injection of miR-998-3p agomir significantly reduced the abundance of ABCC2, accompanied by increased tolerance to Cry1Ac toxin in Heliothis armigera, Spodoptera exigua and Plutella xylostella (Cry-S) larvae, while injection of miR-998-3p antagomir increased the abundance of ABCC2 dramatically, and thereby reduced the Cry1Ac resistance in a Cry1Ac resistant population of P. xylostella (GX-R). [ABCC2] (Mus musculus) PubMed

 24863.

Injection of miR-998-3p agomir significantly reduced the abundance of ABCC2, accompanied by increased tolerance to Cry1Ac toxin in Heliothis armigera, Spodoptera exigua and Plutella xylostella (Cry-S) larvae, while injection of miR-998-3p antagomir increased the abundance of ABCC2 dramatically, and thereby reduced the Cry1Ac resistance in a Cry1Ac resistant population of P. xylostella (GX-R). [ABCC2] (Mus musculus) PubMed

 24864.

EcaB is mainly located in the thylakoid membranes where it interacts with CupA and CupB involved in CO2 uptake by converting it to bicarbonate.[EcaB] (Mus musculus) PubMed

 24865.

The authors show that GacA, the Hypr GGDEF motif protein in Geobacter sulfurreducens, specifically regulates cyclic GMP-AMP (3',3'-cGAMP) levels in vivo to stimulate gene expression associated with metal reduction separate from electricity production.[GacA] (Mus musculus) PubMed

 24866.

a cotton phosphatase GhDsPTP3a and an annexin protein GhANN8b interact and reversely modulate Ca(2+) and Na(+) fluxes in cotton salinity responses.[GhDsPTP3a, GhANN8b] (Mus musculus) PubMed

 24867.

ZmHKT2 underlies maize shoot potassium content and salt tolerance.[ZmHKT2] (Mus musculus) PubMed

 24868.

These results demonstrate the roles of different superoxide dismutase in miR398b-regulated resistance to rice blast disease.[SOD, mir398b] (Mus musculus) PubMed

 24869.

Two novel alpha-l-arabinofuranosidases, BlArafC and BlArafB, degrade arabinan and are required for the efficient growth of bifidobacteria. [BlArafC and BlArafB] (Mus musculus) PubMed

 24870.

Hog1 interacts with and phosphorylates Rds2, a zinc cluster transcription factor, under osmotic stress.[Rds2, Hog1] (Mus musculus) PubMed

 24871.

BZR2 transcription factor functions positively in drought responses by activating GST1 and mediates drought signaling pathways.[BZR2] (Mus musculus) PubMed

 24872.

Residue Y164 of BaSatA was important for binding streptothricin. [SatA] (Mus musculus) PubMed

 24873.

Results demonstrate that SbER2-1 plays an important role in response to drought stress. Furthermore, photosynthetic systems and phenylpropanoid metabolism are implicated in SbER2-1-mediated drought stress tolerance mechanisms. [ER2-1] (Mus musculus) PubMed

 24874.

High level of BvSTI altered morphology and delayed salt stress related senescence, implicating BvSTI gene as a promising tool for salinity tolerance improvement trials in Lotus corniculatus.[STI] (Mus musculus) PubMed

 24875.

New Delhi metallo-beta-lactamase (NDM-19) is a derivative of NDM-7, from which it differs by a single amino acid substitution (Ala233Val). Under zinc-limiting growth conditions, E. coli DH5alpha transformants producing NDM-19 display reduced susceptibility towards expanded-spectrum cephalosporins and carbapenems as compared to transformants producing NDM-1 or NDM-7. (Mus musculus) PubMed

 24876.

Beta-glucan-induced sheep beta-defensin-1 (SBD-1) production was mediated by the activation of dendritic-cell-associated C-type lectin 1 (Dectin-1) receptors, Syk, and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB). [beta-defensin-1] (Mus musculus) PubMed

 24877.

This study shows that Pyruvate dehydrogenase (PDH) is involved in the pathogenesis of S. suis 2 and reduction in virulence of Deltapdh may be related to the decreased ability to resist stress of the strain [PDH]. (Mus musculus) PubMed

 24878.

Results found that FrzB does not interact with FrzW as it lacks the amino acid region responsible for this interaction. FrzB, instead, acts upstream of FrzCD in the regulation of M. xanthus chemotaxis behaviors and activates the Frz pathway allowing the formation and distribution of multiple chemosensory clusters on the nucleoid. [FrzB] (Mus musculus) PubMed

 24879.

FLO10 plays an important role in the maintenance of mitochondrial function and endosperm development through its effect on the trans-splicing of the mitochondrial nad1 intron 1 in rice.[Flo10, nad1] (Mus musculus) PubMed

 24880.

comparison of SigW structures complexed with the -35 promoter element or with anti-sigma RsiW reveals that DNA recognition and anti-sigma factor binding of SigW are mutually exclusive.[SigW] (Mus musculus) PubMed

 24881.

We demonstrate here that PfHOP behaved as a predominantly dimeric protein and presented structural and functional aspects of HOP cochaperones. Our results deepened the knowledge of the structure and function of PfHOP and further clarified its participation in the P. falciparum foldosome. (Mus musculus) PubMed

 24882.

Hippo pathway can modify neurofibromagenesis in Neurofibromatosis type 1 mouse model (hippo gene) (Mus musculus) PubMed

 24883.

Results provide evidence that SpEX likely plays an important role in Staphylococcus pseudintermedius virulence. [SpEX] (Mus musculus) PubMed

 24884.

Sll1217 partially acts as a PGRL1 analogue, the mode of action of PGR5 and PGRL1/Sll1217 proteins is similar in cyanobacteria and plants, and PGRL1 could have evolved from a cyanobacterial ancestor. (Mus musculus) PubMed

 24885.

Data support a model in which MglA-GDP acts as a soluble messenger to convert polar MglA-GTP* into a diffusible MglA-GTP species that re-localizes to the opposite pole during movement reversals. (Mus musculus) PubMed

 24886.

our study isolated a legume Dof-like factor LOW from V. radiata, which affects vasculature development in this species and this change can, in turn, impact petal development and overall morphology of keel blossom (Love on wings [low]) (Mus musculus) PubMed

 24887.

To our knowledge, GdcA is the first DXD-motif glycosyltransferase that inhibits NF-kappaB in immune cells [ GdcA]. (Mus musculus) PubMed

 24888.

observations indicate that although BlsA shares common structural and functional properties with unrelated photoreceptors, it also exhibits unique features that make it a distinct BLUF photoreceptor. (Mus musculus) PubMed

 24889.

Ubiquinone is a required substrate of rhodoquinone biosynthesis protein A (RquA), and the product of the RquA reaction is rhodoquinone. [RquA] (Mus musculus) PubMed

 24890.

This study revealed the pleiotropic role of Spf1-regulated calcium homeostasis in controlling hyphal development in Candida albicans.[Spf1] (Mus musculus) PubMed

 24891.

The effect of S. argenteus on a human cell line was studied. The findings showed high expression levels of alpha-hemolysin Hla resulting in cytolethal properties [Hla]. (Mus musculus) PubMed

 24892.

the expression of activin betaA and betaB was elevated in the ovaries of allotriploids and differential expression in pituitaries during the non-breeding season and the breeding season period [activin betaA; activin betaB] (Mus musculus) PubMed

 24893.

Study shows that ZipD-mediated regulation of the fungal cell wall contributes to the evasion of pro-inflammatory responses and tolerance of echinocandin antifungals, and in turn promoting virulence. [ZipD] (Mus musculus) PubMed

 24894.

These data indicate that Mopex13 and Mopex14, as key components of the peroxisomal docking complex, are indispensable for peroxisomal biogenesis, fungal development and pathogenicity [Mopex13; Mopex14]. (Mus musculus) PubMed

 24895.

A novel enantioselective SGNH family esterase (NmSGNH1) from Neisseria meningitidis, which has sequence similarity to carbohydrate esterase (CE3) family, was catalytically characterized and functionally explored. C-terminal regions affect substrate specificity, activity, and thermostability. [NmSGNH1] (Mus musculus) PubMed

 24896.

The present work reports the cloning of the expressed CYP74B33 gene of carrot (Daucus carota L.) and studies of catalytic properties of the recombinant CYP74B33 protein. CYP74B33 exhibits the 9-allene oxide synthase activity. The preferred substrates of CYP74B33 are 9-hydroperoxides. [CYP74B33] (Mus musculus) PubMed

 24897.

in CAPZA1-overexpressing gastric epithelial cells infected with H. pylori, autolysosome formation is inhibited and CagA escapes autophagic degradation.[cagA] (Mus musculus) PubMed

 24898.

Functional characterization of a delta 12 fatty acid desaturase in Tetrahymena thermophila and its influence in homeoviscous adaptation to low temperature was identified characterized. Cell growth at low temperature was impaired in the knockout strain. [delta 12 fatty acid desaturase] (Mus musculus) PubMed

 24899.

These results suggested that the Qdr2p function is needed for proper biofilm formation and biofilm maintenance in C glabrata as well as biofilm drug resistance towards fluconazole [Qdr2p]. (Mus musculus) PubMed

 24900.

the crystal structures of three Physcomitrella D14/KAI2-like proteins and describe a loop-based mechanism that leads to a permanent widening of the hydrophobic substrate gorge. (Mus musculus) PubMed

 24901.

Only the high-affinity binding mode was observed in the complex with infectious CHIKV, as viral maturation and E3 occupancy appear to influence receptor binding-site usage. (Mus musculus) PubMed

 24902.

Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein. (Mus musculus) PubMed

 24903.

DGK1 and associated lipid mediators modulate rice root architecture.[DGK1] (Mus musculus) PubMed

 24904.

The purified lipase activity reached 5509 U/mg. It showed high activity toward short-chain triacylglyceride (C4), and the optimum temperature and pH were 40 degrees C and 8.0, respectively. The purified enzyme activity was inhibited by Zn(2+) and Cu(2+). Moreover, the Km and Vmax values were 1mM and 32.89mmol/min, respectively. [lipase] (Mus musculus) PubMed

 24905.

Inactivation of SAUSA300_1968 enhanced Staphylococcus aureus survival in mouse macrophages. These data provide novel insights into the role of the SAUSA300_1968 transcriptional regulator in host immune evasion and Staphylococcus aureus pathogenesis.[SAUSA300_1968] (Mus musculus) PubMed

 24906.

This study is the first to report on the involvement of Cas9 in the regulation and pathogenesis of Riemerella anatipestifer.[Cas9] (Mus musculus) PubMed

 24907.

The current study discovered a new extracellular poly(3-hydroxybutyrate) [P(3HB)] depolymerase enzyme from Burkholderia cepacia isolated and purified to homogeneity from the culture supernatant. [poly(3-hydroxybutyrate) depolymerase] (Mus musculus) PubMed

 24908.

The authors found that new propellers evolve continuously by amplification from single blades. One- to six-bladed building blocks derived from two seven-bladed WD40 propellers yielded stable homo-oligomers with six to nine blades, depending on the size of the building block.[PkwA] (Mus musculus) PubMed

 24909.

NarP interacted with the promoter regions of five selected target genes, including dmsA, pgaA, ftpA, cstA and ushA. [NarP] (Mus musculus) PubMed

 24910.

Abscissic acid application could induce the expression of jasmonate (JA) biosynthetic genes and then increase the JA concentrations partially dependent on the function of ABI5, consequently leading to the degradation of JAZ proteins.[ABI5] (Mus musculus) PubMed

 24911.

The authors show that Cas4 interacts directly with Cas1-Cas2 forming a Cas4-Cas1-Cas2 complex that captures and processes prespacers prior to integration. Structural analysis of the Cas4-Cas1-Cas2 complex reveals two copies of Cas4 that closely interact with the two integrase active sites of Cas1, suggesting a mechanism for substrate handoff following processing.[Cas4, Cas1, Cas2] (Mus musculus) PubMed

 24912.

Japonica OsNR2 alleles encoding structurally distinct protein with greater NR activity. [NR2] (Mus musculus) PubMed

 24913.

The substrate specificity of neutral sphingomyelinase (TbnSMase) was investigated using electrospray ionization tandem mass spectrometry. Recombinant TbnSMase was shown to degrade sphingomyelin, inositol-phosphoceramide and ethanolamine-phosphoceramide sphingolipid substrates, consistent with the sphingolipid complement of the parasites. (Mus musculus) PubMed

 24914.

transcription factor that regulates reproductive growth and development - [NF-YB9] (Mus musculus) PubMed

 24915.

AhyIcatalyzed the formation of N-butanoyl-l-homoserine lactone using S-adenosyl-l-methionine (SAM) and butyryl-acyl carrier protein (ACP) as substrates and indicated that the fatty acyl substrate used in AhyI-mediated AHL synthesis is derived from acyl-ACP rather than acyl-CoA.[AhyI] (Mus musculus) PubMed

 24916.

AtaT-AtaR proteins form a heterohexameric [AtaT-(AtaR4)-AtaT] complex, where two V-shaped AtaR dimers bridge two AtaT molecules. The N-terminal region of AtaR is required for its dimerization, and the C-terminal region of AtaR interacts with AtaT. AtaT alone forms a dimer in solution, which is enzymatically active. AtaR represses AtaT activity by preventing it from forming an active dimer. [AtaT, AtaR] (Mus musculus) PubMed

 24917.

Study constructed and evaluated an action spectrum for the expression of photoperiodically controlled TSHB in the pituitary gland and identified mammal-like melanopsin (OPN4m), expressed in the infundibular nucleus within the mediobasal hypothalamus, as a candidate deep-brain photoreceptive molecule in Japanese quail. [OPN4m] (Mus musculus) PubMed

 24918.

Increasing the level of Bm30K-3 acetylation by adding the deacetylase inhibitor trichostatin A (TSA) increased the levels of this protein and further inhibited cellular apoptosis induced by H2 O2 . In contrast, decreasing the level of acetylation by adding the acetylase inhibitor C646 could reduce the level of Bm30K-3 and increase H2 O2 -induced apoptosis. [30k-3] (Mus musculus) PubMed

 24919.

miR-9-5p as a mediator of hypoxic injury in cardiomyoblasts and miR-9-5p suppression prevents cardiac remodeling after acute MI, providing a potential strategy for early treatment against MI. (Mus musculus) PubMed

 24920.

The authors determined a crystal structure of GltTk with bound D-aspartate at 2.8 A resolution. Comparison of the L- and D-aspartate bound GltTk structures revealed that D-aspartate is accommodated with only minor rearrangements in the structure of the binding site.[GltTk] (Mus musculus) PubMed

 24921.

suppression promotes tolerance against Clavibacter nebraskensis - [Pgb1.1] (Mus musculus) PubMed

 24922.

This work establishes foxQ2 as a key regulator of brain midline structures, which distinguish the protocerebrum from segmental ganglia.[foxQ2] (Mus musculus) PubMed

 24923.

In the absence of Fe(2+), Fur could specifically bind to the promoter DNA of ompU, while in the presence of Fe(2+), the binding of Fur and the promoter DNA was suppressed. [ompU] (Mus musculus) PubMed

 24924.

MDR1 is highly expressed in the triazole-resistant clinical isolates of C. auris.[MDR1] (Mus musculus) PubMed

 24925.

These data reveal how the ethylene-inhibited primary root elongation is finely controlled by OsDOF15 in response to environmental signal.[OsDOF15] (Mus musculus) PubMed

 24926.

Alternative isoforms of Yki have different transcriptional co-activator activity in the Bombyx mori. [Yki] (Mus musculus) PubMed

 24927.

Gene expression levels for mch and pomc were reciprocally different depending on background color.[mch, pomc] (Mus musculus) PubMed

 24928.

Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase. (Mus musculus) PubMed

 24929.

Comparison of the obtained structures with those of other aminoglycoside phosphotransferases revealed peculiar structure of the substrate-binding pocket reflecting its specificity to a particular antibiotic[aminoglycoside phosphotransferase 3] (Mus musculus) PubMed

 24930.

Global H-NS counter-silencing by LuxR activates quorum sensing gene expression. [LuxR]; [H-NS] (Mus musculus) PubMed

 24931.

MG236 protein of M. genitalium shows sequence homology to the Fur family, that control metal homeostasis; mutagenesis of the predicted Fur operator within the hrl promoter abrogated Fur- & metal-dependent expression of a reporter gene. Metal starvation still impelled a strong transcriptional response in the fur mutant, showing the existence of Fur-independent regulatory pathways controlling metal homeostasis.[MG236] (Mus musculus) PubMed

 24932.

These results showed a novel role for OsCBL1 in the regulation of nitrate signaling and nitrate-mediated rice growth.[OsCBL1] (Mus musculus) PubMed

 24933.

aerobactin- or rmpA-positive Klebsiella pneumoniae still exhibit high virulence and anti-immune effect activity.[rmpA] (Mus musculus) PubMed

 24934.

spermatozoa-derived circNAPEPLDiso1 physically interacts with miRNAs primarily involved in the control of cell cycle.[circNAPEPLD] (Mus musculus) PubMed

 24935.

This study describes a new signalling pathway for NLR protein-mediated blast resistance and shows that OsRac1 and RAI1 act together to play a critical role in this process.[OsRac1, RAI1] (Mus musculus) PubMed

 24936.

a major quantitative trait loci for kernel row number, krn1, which is likely to correspond to an existing gene (ids1/Ts6) encoding an AP2 domain protein.[Krn1] (Mus musculus) PubMed

 24937.

miR-195a might bind to circRNA_28313 and CSF1 and together form a circRNA-miRNA-mRNA network.[CircRNA_28313] (Mus musculus) PubMed

 24938.

results demonstrated Ac154 could delay apoptosis process in host cells by regulating the transcription of p35 gene and the expression of SfP53 protein, which provided a more favorable environment for progeny virus replication and packaging, thereby promoting the proliferation of progeny virus. (Mus musculus) PubMed

 24939.

Study shows the critical role of the HAV capsid codon composition in regulating translation and determining its robustness [capsid protein] (Mus musculus) PubMed

 24940.

using a non-essential minichromosome in fission yeast, we identify roles for the Homologous recombination repair factors Rqh1 helicase, in concert with Rad55, in suppressing de novo telomere addition (dnTA) at or near a DSB (Mus musculus) PubMed

 24941.

MtLYK9 thus has a dual role in plant immunity and the arbuscular mycorrhizal symbiosis.(MtLYK9) (Mus musculus) PubMed

 24942.

Surgical trauma contributes to colon cancer progression by increasing CCL18 expression, promoting Treg recruitment, and leading to an immunosuppressive environment. (Mus musculus) PubMed

 24943.

The authors concluded that the free C-terminal domain blocks the formation of ParB networks by heterodimerisation with full length DNA-bound ParB. This strongly supports a model in which the C-terminal domain acts as a key bridging interface between distal DNA binding loci within ParB networks.[ParB] (Mus musculus) PubMed

 24944.

Two hybrid mutants containing the N-terminal fragments of CYP52A21 and C-terminal fragments of CYP52A23 displayed higher catalytic activity in palmitic acid and arachidic acid[CYP52A23] (Mus musculus) PubMed

 24945.

precursor microRNA-14 (pre-miR-14) encodes two mature miRNAs in silkworm; both of these two mature miRNAs regulate various genes in the ecdysone-signalling pathway.[mir 14] (Mus musculus) PubMed

 24946.

CrhR impacts multiple aspects of RNA metabolism in Synechocystis.[CrhR] (Mus musculus) PubMed

 24947.

Collectively, MoLEU1, MoLEU2, and MoLEU4 regulated by MoLEU3 play crucial roles in fungal development and infectious processes through modulation of leucine biosynthesis in Magnaporthe oryzae.[ MoLEU1, MoLEU2, MoLEU3, MoLEU4] (Mus musculus) PubMed

 24948.

Pathway dissection revealed that Mkt1 is required for RNAi-mediated post-transcriptional silencing, downstream of small RNA production. Mkt1 physically associates with pericentromeric transcripts, and is additionally required for maintenance of silencing and heterochromatin at centromeres when transcriptional silencing is impaired. (Mus musculus) PubMed

 24949.

Scd6 self-interaction competes with eIF4G1 binding and methylation of Scd6 RGG-motif by Hmt1 negatively affects self-association.[eIF4G, Scd6] (Mus musculus) PubMed

 24950.

These results identify Abscissic acid as a substrate of the LR34 ABC transporter.[LR34] (Mus musculus) PubMed

 24951.

Bal6GBP has a 1630-fold higher selectivity for beta-(1,6)-galactobiose, reflected in dramatic differences in growth, with several hours lag on less preferred beta-(1,4)- and beta-(1,3)-galactobiose. The preferred substrate was preferentially depleted from the culture supernatant. (Mus musculus) PubMed

 24952.

The variability in susceptibility to neutrophil extracellular traps-mediated killing of pneumococcal strains is attributed to PspA, as strains lacking the surface expression of PspA were significantly more sensitive to NETs-mediated killing compared to the wild-type strains.[PspA] (Mus musculus) PubMed

 24953.

Three paralogous genes (BST1, BST2, and BST3) belonging to the bestrophin family have been found to be up-regulated in low CO2 conditions, and their expression is controlled by CIA5, a transcription factor that controls many CCM genes. (Mus musculus) PubMed

 24954.

data suggest that CsBRC1 inhibits lateral bud outgrowth by direct suppression of CsPIN3 functioning and thus auxin accumulation in axillary buds in cucumber, providing a strategy to breed for cultivars with varying degrees of shoot branching grown in different cucumber production systems. (Mus musculus) PubMed

 24955.

The results suggest that nsp1, alone, can regulate multiple steps of gene expression including nuclear-cytoplasmic transport. (Nsp1 protein, SARS coronavirus). (Mus musculus) PubMed

 24956.

Using single-particle cryo-electron microscopy this study determined the low-resolution structures of a VacA dodecamer and heptamer, as well as a 3.8-A structure of the VacA hexamer. [VacA] (Mus musculus) PubMed

 24957.

Orb6 phosphorylation of Sec3 contributes to exocyst function in concert with exocyst protein Exo70. [Sec3] (Mus musculus) PubMed

 24958.

These findings reveal that MavN is a transition-metal-ion transporter that plays a critical role in response to iron limitation during Legionella infection. (Mus musculus) PubMed

 24959.

role as Rubisco-specific assembly chaperone that forms intermediary hetero-oligomeric complexes, and is nonlimiting to growth - [BSD2] (Mus musculus) PubMed

 24960.

Results show the presence of a His-Asp/Glu dyad forming the core of EnvZ histidine kinase osmosensing wherein osmolytes mediate changes in the backbone and side-chain microenvironment, leading to enhanced histidine autophosphorylation. [EnvZ] (Mus musculus) PubMed

 24961.

These results provide insight into how the bi-substrate enzyme DXPS limits side reactions by arresting the reaction on the less reactive LThDP intermediate when its cosubstrate is absent. They also offer a molecular basis for previous low-resolution experimental observations that correlate decarboxylation of LThDP with protein conformational changes. (Mus musculus) PubMed

 24962.

The study reports a 2.3 A crystal structure of the Cry7Ca1 toxin and carry out a systematic comparison of all available Cry toxins structures. A cluster of six loops in Cry toxin domain II, named Apex here, are the most variable structural elements and were documented to contribute in insecticidal specificity. [Cry7Ca1 toxin] (Mus musculus) PubMed

 24963.

These results demonstrated that the autophagy induced in Pichia pastoris cells grown in amino acid-rich methanol medium was nitrogen source independent and may be due to a Gcw13-dependent decrease in amino acid uptake during methanol adaptation.[Gcw13] (Mus musculus) PubMed

 24964.

Substitution of cysteines except C89 and C223 with serine residues led to the reduction of the RdRp activity of the recombinant protein in a primer-dependent assay.[RdRp] (Mus musculus) PubMed

 24965.

This study highlights the role of gamma-aminobutanal dehydrogenase in maintaining an intact tricarboxylic acid cycle in Synechocystis. [gamma-aminobutanal dehydrogenase] (Mus musculus) PubMed

 24966.

PFKB1 functions as a novel regulator indispensable for early chloroplast development, at least partly by regulating chloroplast-associated genes.[PFKB1] (Mus musculus) PubMed

 24967.

may inhibit microtubule nucleation [CopN] (Mus musculus) PubMed

 24968.

The results presented here suggest that OsPUB41 is possibly involved in elicitation of CWDE triggered immune responses in rice. [PUB41] (Mus musculus) PubMed

 24969.

PtHDT902 worked as an important regulator in adventitious root formation and salt stress tolerance in poplar. [HDT902] (Mus musculus) PubMed

 24970.

BrfA binds to non-stop stalled ribosomes, recruits homologous RF2, but not RF1, and induces its transition into an open active conformation.BrfA expression is regulated by trans-translation.[BrfA] (Mus musculus) PubMed

 24971.

This study presents a novel residue-interaction network approach to determine how near-neighbor interactions of protease inhibitor resistance mutations in NS3-4A Protease can impact protease functional sites dependent on their genomic background. [NS3-4A Protease] (Mus musculus) PubMed

 24972.

Data report crystal structures of VcmN, a Vibrio cholerae MATE transporter driven by the H+ gradient. High-resolution structures in two distinct conformations associated with different pHs revealed that the rearrangement of the hydrogen-bonding network around the conserved Asp35 induces the bending of transmembrane helix 1. [VcmN] (Mus musculus) PubMed

 24973.

to understand the molecular mechanism by which DnaC/DnaI opens the DnaB ring, we solved 3.1-A co-crystal structure of the interaction domains of Escherichia coli DnaB-DnaC [DnaB & DnaC] (Mus musculus) PubMed

 24974.

substrate promiscuity in bacterial galactokinases [Galactokinase] (Mus musculus) PubMed

 24975.

high-resolution cryo-EM structures that delineate the full functional cycle of an asymmetric ABC exporter in a lipid environment {TmrA & TmrB] (Mus musculus) PubMed

 24976.

A role of Mfd in replication-transcription conflicts IS REVIEWED. The different physical states of RNAP during transcription are discussed, and how each distinct state can influence conflict severity and potentially trigger the involvement of Mfd. (Mus musculus) PubMed

 24977.

This discovery that simultaneously active expression sites dynamically share a single expression-site body demonstrates the importance of this unique subnuclear body in restricting the monoallelic expression of VSG.[VSG] (Mus musculus) PubMed

 24978.

A gene encoding O antigen polymerase (O antigen ligase) that contains the Wzy_C superfamily domain (herein designated as Ocw) was identified in E. coli RS218. Ocw affects the lipopolysaccharide synthesis, ROS tolerance, and survival of E. coli in the host environment.[Ocw] (Mus musculus) PubMed

 24979.

T4 phage lysozyme (T4L) is an enzyme that cleaves bacterial cell wall peptidoglycan. These results provide important constraints for understanding the catalytic mechanisms by which the wild-type and mutant form of T4 lysozyme cleave bacterial peptidoglycan. [T4 lysozyme] (Mus musculus) PubMed

 24980.

the ERA8 ABA-hypersensitive germination phenotype results from the MAP kinase MKK3-A-G1093A missense mutation [MKK3] (Mus musculus) PubMed

 24981.

Gid10 can function as a specific N-recognin of the Pro/N-degron pathway.[Gid10] (Mus musculus) PubMed

 24982.

Very hydrophobic segments (e.g., 16Leu) are stably incorporated into the inner membrane, resulting in a C-terminal anchored membrane protein, while a 24L construct was not targeted to the membrane by SecA and remained in the cytoplasm. [SecA] (Mus musculus) PubMed

 24983.

GLE1 plays a distinct role in the symbiotic association between lotus and rhizobia. [GLE1] (Mus musculus) PubMed

 24984.

Overexpression or knockdown of HDAC1, SIN3, or both resulted in a decrease or increase in Kr-h1 mRNA levels and its promoter activity, respectively. Overexpression of the JH receptor Methoprene tolerant (Met) was unable to induce Kr-h1 in the presence of HDAC1 or SIN3. (Mus musculus) PubMed

 24985.

lncRNA LINC01980 promotes esophageal squamous cell carcinoma (ESCC) cells growth and proliferation in vitro and in vivo. LINC01980 accelerates cell cycle progression and prevents cell apoptosis. [lncRNA LINC01980] (Mus musculus) PubMed

 24986.

An Escherichia coli strain lacking Isoleucyl-tRNA Synthetase post-transfer editing misincorporated norvaline and valine in the proteome to a similar extent and at the same Ile positions. [Isoleucyl-tRNA Synthetase] (Mus musculus) PubMed

 24987.

The macro domain (MD) of Mayaro virus (MAYV) belongs to the N-terminal region of its non-structural protein 3, part of the replication complex. MAYV MD selectivity and binding of ADP-ribose are revealed by NMR spectroscopy. (Mus musculus) PubMed

 24988.

In Synechococcus elongatus regulatory protein PipX enhances in cis of pipY expression. Prevention of polarity at the pipXY operon is independent of pipY or its gene products, requires both coding and non-coding pipX sequences, and importantly, coding sequences are also required in cis. The TLD/KOW domain of PipX establishes a structural and functional link between this unique cyanobacterial protein. (Mus musculus) PubMed

 24989.

an auxin influx carrier that regulates root development and responses to aluminum stress - [AUX3] (Mus musculus) PubMed

 24990.

This is the first comprehensive study on the interaction between CLCuMB-betaC1 and Gh-CML11 proteins which provided insights into our understating of the role of betaC1 in cotton leaf curl disease. (Mus musculus) PubMed

 24991.

The results demonstrate that OsSHI1 regulates plant architecture through modulating the transcriptional activity of IPA1 and provide insight into the establishment of plant architecture in rice. [SHI1] (Mus musculus) PubMed

 24992.

PpCRN7 and PpCRN20 have the ability to increase P. parasitica pathogenicity and may play important roles at different stages of infection. These PpCRN-associated mechanisms are now targets of biotechnological studies aiming to break pathogen's virulence and to promote plant resistance. [CRN7,CRN20] (Mus musculus) PubMed

 24993.

One of the H. pylori type IV secretion system components, protein CagL, can act as a flagellin-independent TLR5 activator. CagL contains a D1-like motif that mediates adherence to TLR5+ epithelial cells, TLR5 activation, and downstream signaling in vitro. TLR5 expression is associated with H. pylori infection and gastric lesions in human biopsies. CagL, by activating TLR5, may modulate immune responses to H. pylori.[CagL] (Mus musculus) PubMed

 24994.

The study presents the results of a directed evolution approach to the engineering of a dimeric, blunt end cutting restriction enzyme NlaIV (GGN/NCC). Determined is the crystal structure of NlaIV. [NlaIV Restriction Endonuclease] (Mus musculus) PubMed

 24995.

alternative binding motif for human neutrophil elastase in EapH1 and EapH2 [EapH1][EapH2] (Mus musculus) PubMed

 24996.

These results suggest that the Soluble lytic transglycosylase SLT of F. novicida is required for immune suppression and escape from autophagy to allow its survival in host cells. [Soluble lytic transglycosylase] (Mus musculus) PubMed

 24997.

Activity of spore-specific respiratory nitrate reductase 1 (NAR1) of Streptomyces coelicolor A3(2) requires a functional Cytochrome bcc-aa 3 oxidase supercomplex. [NAR1] (Mus musculus) PubMed

 24998.

A miRNA hosted in ribosomal DNA is involved in vertebrate development.[ miR-ntu1; zebrafish] (Mus musculus) PubMed

 24999.

We show that TagL comprises an N-terminal domain that mediates contact with the trans-envelope channel and a peptidoglycan-binding domain that binds the cell wall [TagL]. (Mus musculus) PubMed

 25000.

results demonstrated that the MurI knockout leads to the generation of S. iniae auxotroph with damaged cell walls [MurI] (Mus musculus) PubMed

 25001.

The induction of trehalose by ethanol required the alternative sigma factor AlgU through DksA- and SpoT-dependent (p)ppGpp [AlgU]. (Mus musculus) PubMed

 25002.

We show that EipB is secreted to the periplasm where it forms a spiral-shaped antiparallel beta protein that is a determinant of cell envelope integrity in vitro and virulence in an animal model of disease [EipB]. (Mus musculus) PubMed

 25003.

Study shows that inactivation of the pgfur gene exerts a different influence on the phenotype of Porphyromonas gingivalis A7436 and ATCC 33277 strains. These findings further support the hypothesis that PgFur regulates the expression of genes encoding surface virulence factors and/or genes involved in their maturation. [pgFur] (Mus musculus) PubMed

 25004.

The identification of regulatory proteins in the DRBD2-mRNP complex corroborates the important role of DRBD2 in gene expression regulation in Trypanosoma cruzi. [DRBD2] (Mus musculus) PubMed

 25005.

study expands our mechanistic understanding of LsdA and related stilbene-cleaving dioxygenases [LsdA] (Mus musculus) PubMed

 25006.

Mutation of the G4 motif of FeoB abolished the GTPase activity but not ATPase activity. [ FeoB ] (Mus musculus) PubMed

 25007.

Under oxygen-limited conditions, DicF enhances global expression of the EHEC type three secretion system, which is a key virulence factor required for host colonization, through the transcriptional activator PchA (Mus musculus) PubMed

 25008.

OsRac1 modulates rice grain size and yield by influencing cell division.[OsRac1] (Mus musculus) PubMed

 25009.

GhHSP24.7 modulates CytC/C1 production to induce reactive oxygen species generation, which consequently accelerates endosperm rupture and promotes seed germination.[HSP24.7] (Mus musculus) PubMed

 25010.

In this study, the histone-like proteins MvaT and MvaU are added to the growing list of global regulators that control the type III secretion system the primary effect of MvaT/MvaU on T3SS gene expression is through direct silencing of the P exsA promoter. [MvaU] (Mus musculus) PubMed

 25011.

strain c1 NADH-oxidase In strain C1 (ATCC 30001) which is known to lack NADH oxidase activity completely, the NADH oxidase gene has a deletion at position 1540 of the open reading frame leading to a frame shift and, as a consequence, to premature termination of the encoded polypeptide. (Mus musculus) PubMed

 25012.

MMAR_2894 is a PE protein secreted by the ESX-1 system. MMAR_2894 is required for the optimal secretion of mycobacterial proteins required for disease [MMAR_2894] (Mus musculus) PubMed

 25013.

During the L3 and L4 stages, Met mediates Juvenile hormones suppression of pupal/adult genes involved in the synthesis and melanization of the cuticle and blood meal digestion. [Met] (Mus musculus) PubMed

 25014.

Csd7 collaborates with other proteins to stabilize the cell wall-degrading enzyme Csd1. Csd7 also links Csd1 with a putative filament-forming protein via protein-protein interactions. [Csd1; Csd7] (Mus musculus) PubMed

 25015.

T. thermophilus possesses a complicated regulatory mechanism of Glutamate dehydrogenase (GDH) to control carbon and nitrogen metabolism [GDH]. (Mus musculus) PubMed

 25016.

We purport that MtlS serves as a stringent brake that limits expression of mtlA, reserving full expression only for conditions in which mannitol utilization is metabolically favored [mtlS]. (Mus musculus) PubMed

 25017.

BagAB is not required for M. tuberculosis pathogenesis in mice. BagA and BagB are unlikely to be involved in anion transport. [BagA; BagB] (Mus musculus) PubMed

 25018.

Two pale green mutants of the green alga Chlamydomonas reinhardtii, which have been used over the years in many photosynthesis studies, the BF4 and p71 mutants, were characterized and their mutated gene identified in the nuclear genome.[BF4, p71] (Mus musculus) PubMed

 25019.

GAPDH-CP12 has exchanged NADPH for NADH, and then captures PRK dimers to form a ternary complex. [GAPDH,CP12, PRK] (Mus musculus) PubMed

 25020.

Determined is the crystal structure of the GP2 fusion glycoprotein from the spike complex of LASV (GP2LASV) in its post-fusion conformation. [GP2 fusion glycoprotein] (Mus musculus) PubMed

 25021.

High expression of Hoxaas3 was associated with pulmonary artery smooth muscle cell proliferation and cell cycle regulation by up-regulating Homeobox a3 at the mRNA and protein levels. (Mus musculus) PubMed

 25022.

BimEL IGF-1 inhibited porcine primary granulosa cell apoptosis via degradation of pro-apoptotic BimEL. (Mus musculus) PubMed

 25023.

The substrate-free adenylate kinase prefers an open conformation, but changes to a closed state once ATP.Mg enters into its binding pocket first and then AMP does. After the reaction of ATP transferring the terminal phosphate group to AMP, ADP.Mg and ADP are released sequentially, and finally the whole catalyze cycle is completed. [adenylate kinase] (Mus musculus) PubMed

 25024.

Tschy facilitated the larval intrusion of the host's enteral epithelium and could be a candidate molecular target for vaccine against the enteral invasive phase of T. spiralis. [chy] (Mus musculus) PubMed

 25025.

Study determined crystal structures of the apo and manganese-bound forms of MntR from B. halodurans at 2.3 A resolution. Structural data about MntR from B. halodurans supports the previous hypothesizes about manganese-specific activation mechanism of MntR homologues.[MntR] (Mus musculus) PubMed

 25026.

VvHB58 has a potential function in regulating fruit and seed development by impacting multiple hormonal pathways (HB58) (Mus musculus) PubMed

 25027.

Crystal structure of TsiT shows a typical alpha + beta class protein belonging to a novel Imm52 protein family of the polymorphic toxin system. [TsiT] (Mus musculus) PubMed

 25028.

Cyclic di-GMP co-activates the two-component transcriptional regulator DevR in Mycobacterium smegmatis in response to oxidative stress [DevR] (Mus musculus) PubMed

 25029.

The multipolar spindles failed to transition into bipolar ones in OsmtopVIB with the defect in double-strand break (DSB) formation.[OsmtopVIB] (Mus musculus) PubMed

 25030.

the results reveal that hemin-mediated vacuolar targeting of Shu1 requires Ubi4-dependent ubiquitination, the receptor Nbr1 and the endosomal sorting complexes required for transport proteins Hse1 and Sst6. [Shu1] (Mus musculus) PubMed

 25031.

[elF5B] the dissociation of eIF5B serves as a kinetic checkpoint for the transition from initiation to elongation (Mus musculus) PubMed

 25032.

This study bioinformatically, biochemically, and biophysically characterized PscN as a Type Three Secretion Systems ATPase and PscL as its regulator. [PscN, PscL] (Mus musculus) PubMed

 25033.

The crystal structure of the complex and a small-angle X-ray scattering analysis revealed that the phosphate ion at the protein-DNA interface affected the DNA binding mode of MoSub1 to oligo-DNA and provided a new structural clue for studying its functions. [MoSub1] (Mus musculus) PubMed

 25034.

Deletion of glaR disabled galactose utilization and abrogated or decreased expression of the gal-lac genes. The GlaR-dependent regulation of the gal-lac operon depends on its specific binding to a DNA region upstream of the lacS gene activating lacS expression and increasing the expression of the operon genes localized downstream.[GlaR] (Mus musculus) PubMed

 25035.

suggest that interactions of Arg92 with heme-bound ligand induce alterations in the distance between subunits, which plays a key role in controlling the heme degradation activity of HutZ[HutZ] (Mus musculus) PubMed

 25036.

In this study, the authors report that Ino-1 plays an important role in oxidative stress resistance in the gram-positive Actinobacteria Corynebacterium glutamicum.[ Myo-inositol-phosphate synthase Ino-1] (Mus musculus) PubMed

 25037.

The results showed that the region encoding the C-terminus of HA76 was essential for nucleocapsid assembly, whereas the N-terminal cysteine-rich region was responsible for oral infection. Electron microscope analyses further showed that the cysteine-rich region contributed to morphogenesis of occlusion bodies (OBs), with amino acids 136-223 of HA76 being critical for this function.[HA76] (Mus musculus) PubMed

 25038.

LvPPAE2 knockdown contributed to decreased expression of antimicrobial peptides LvAlf1 and LvLyz1, reduced hemolymph phenoloxidase activity, and increased virus load, suggesting that LvPPAE2 is involved in the host defense against white spot syndrome virus infection.[Alf1,Lyz1] (Mus musculus) PubMed

 25039.

The study reports the 2.08 A resolution structure of HLB5, a chemically verified cellulase that was identified previously from an anaerobic gut bacterium and that has no structural cellulase homologues in PDB nor possesses any conserved region typical for glycosidases. [HLB5] (Mus musculus) PubMed

 25040.

New P. aeruginosa surface proteins were identified by reverse vaccinology and tested in vivo as potential vaccine antigens. Three of these, namely PSE17-1, PSE41-5 and PSE54, were screened for glycan binding using glycan arrays displaying glycan structures representative of those found on human cells. All three proteins are novel lectins. [PSE17-1, PSE41-5, PSE54] (Mus musculus) PubMed

 25041.

We present high-resolution structures of Deinococcus radiodurans (Dra)Nramp in multiple conformations to provide a thorough description of the Nramp transport cycle by identifying the key intramolecular rearrangements and changes to the metal coordination sphere. (Mus musculus) PubMed

 25042.

Camelina sativa rare cold-inducible 2 (RCI2), RCI2E and RCI2F proteins interact with aquaporin PIP2; 1 in Camelina plasma membrane under normal and NaCl stress. [RCI2F] (Mus musculus) PubMed

 25043.

These data show that Legionella pneumophila effector protein SidJ modifies another Legionella effector SdeA, an unconventional phosphoribosyl ubiquitin ligase, by adding glutamate molecules to a specific residue of SdeA in a CaM-dependent manner.[SidJ, SdeA] (Mus musculus) PubMed

 25044.

Lv-POLR2H was mainly located in the secondary gill filaments, the transcript levels of Lv-POLR2H in the gills were found to be significantly affected after challenge by pH, low salinity and high concentrations of NO2(-) and NH4(+), indicating that Lv-POLR2H in gill tissues might play roles under various physical stresses. [POLR2H] (Mus musculus) PubMed

 25045.

Study demonstrated ATP-dependent histone H3-H4 deposition onto DNA by Abo1, the fission yeast ortholog of ATAD2, using an in vitro single-molecule imaging technique, the DNA curtain and solved the cryo-EM structures of Abo1 in three different nucleotide states (apo, ADP, and ATP), revealing a major reorganization of the AAA+ domains from an open spiral to a closed ring.[Abo1] (Mus musculus) PubMed

 25046.

In this study, the authors described the mutations found in gaaX and gaaR that enabled constitutive (i.e., inducer-independent) expression of pectinases by Aspergillus niger.[gaaR] (Mus musculus) PubMed

 25047.

recycling requires the AP-1 adaptor, suggesting that AP-1 can recycle secretory cargo proteins as well as resident Golgi proteins[AP1]+ (Mus musculus) PubMed

 25048.

Ethylene receptor OsERS2, via its GAF domain, physically interacts with MHZ1/OsHK1 and inhibits its kinase activity.[OsERS2, MHZ1] (Mus musculus) PubMed

 25049.

The results show that the the amphipathic helix (AH) is dispensable for membrane anchoring of NS5A. Instead, AH plays a dual role in the viral replicase assembly: positions a replicase module properly for efficient polyprotein processing and participates in protein-protein interactions within the replicase. (Mus musculus) PubMed

 25050.

HIF1AN was confirmed as a direct target of miR-135-5p. [miR-135-5p] (Mus musculus) PubMed

 25051.

The X-ray crystallographic structure of the mature form of subtilisin E-S7 (SES7) at 1.90A resolution is reported here. [subtilisin E-S7] (Mus musculus) PubMed

 25052.

Crystal structure of Parvibaculum Baeyer-Villiger monooxygenase (BVMO) was determined as a NADPH complex form. Parvibaculum BVMO has a rigid bulge at the oxygenase site. Parvibaculum BVMO has a large pocket at the initial substrate binding site. [Baeyer-Villiger monooxygenase] (Mus musculus) PubMed

 25053.

HSP70 role in the liver ischemia/reperfusion injury.INOS increases the HSF1 binding to the HSP70 gene promoter in the hepatocytes after ischemia/reperfusion injury.INOS increases HSP70 expression in the hepatocytes after ischemia/reperfusion injury.[HSP70] (Mus musculus) PubMed

 25054.

Enterococcus faecalis sir2-like gene enhances aerobic metabolism of themselves and mitochondrial respiration of mammal cells to bring about improving metabolic syndrome through the PGC-1alpha pathway. (Mus musculus) PubMed

 25055.

FACT and Ubp10 may coordinate nucleosome assembly during DNA replication and transcription.[FACT, Ubp10] (Mus musculus) PubMed

 25056.

The C-terminal region of L protein played an essential role in the viral transcription. [L protein] (Mus musculus) PubMed

 25057.

Chaperone trigger factor forms complex with ribosomal protein S7.[chaperone trigger factor and ribosomal protein S7] (Mus musculus) PubMed

 25058.

Study reports daily oscillations of gene expression and cell fluorescence in the diatom Phaeodactylum tricornutum, which persist in the absence of external timing cues. Protein RITMO1, encoded by a bHLH-PAS gene, which is widely represented in algal genomes, regulates these rhythms. Study unveils critical features of diatom biology, thus advancing the field of diurnal and circadian rhythms in marine algae.[RITMO1] (Mus musculus) PubMed

 25059.

A viral small terminase subunit (TerS) twin ring pac synapsis DNA packaging model is supported by fluorescent fusion proteins. [TerS] (Mus musculus) PubMed

 25060.

IGF-motif loops project from the hexameric ring of ClpX and are required for docking with the self-compartmentalized ClpP peptidase, which consists of heptameric rings stacked back-to-back.This study shows that ATP or ATPgammaS support assembly by changing the conformation of the ClpX ring, bringing the IGF loops closer to each other and allowing efficient multivalent contacts with docking clefts on ClpP. [ClpX] (Mus musculus) PubMed

 25061.

SCCmec type V was the predominant type seen in half of the isolates. More studies need to be done in different parts of the country on a large number of isolates to confirm our findings. (Mus musculus) PubMed

 25062.

B. subtilis triggers the induction of the stress-responsive sigma B transcription factor and the synthesis of the lipopeptide surfactin to fight the phytopathogen Fusarium verticillioides.[SigB] (Mus musculus) PubMed

 25063.

The pathogen Salmonella achieves a proper response of Fur to changes in environmental iron concentrations via EIIA(Ntr) (a nitrogen metabolic phosphotransferase system component). [EIIA] (Mus musculus) PubMed

 25064.

An active FTL9 allele is required for the acquisition of floral competence, demonstrating a novel role for a member of the FT family of genes.[FLT9] (Mus musculus) PubMed

 25065.

MsbA is a prototypical member of the ATP binding cassette protein superfamily. MsbA activity was higher in nanodiscs vs detergent, which had clear structural correlates: an increase in the fraction of molecules displaying closed nucleotide-binding domain dimers in the apo state, and a decrease in the distance of the "dissociated" nucleotide-binding domains. [MsbA] (Mus musculus) PubMed

 25066.

This study reports that the gene SAMN03097714_1080 from the P. ananatis indeed, encode for an N-formyltransferase, hereafter referred to as PA1080c. the X-ray structure of PA1080c, determined to 1.7 A resolution, shows that the enzyme adopts the molecular architecture observed for other sugar N-formyltransferases. [N-formyltransferase] (Mus musculus) PubMed

 25067.

The specific activity of recombinant glyceraldehyde-3-phosphate dehydrogenase constituted 55mumol NADH/min per mg. [glyceraldehyde-3-phosphate dehydrogenase] (Mus musculus) PubMed

 25068.

Genome-Wide Analysis of the YABBY Transcription Factor Family in Pineapple and Functional Identification of AcYABBY4 Involvement in Salt Stress. (Mus musculus) PubMed

 25069.

PvTOR plays an important role in the adaptation mechanisms of shrimp at low temperature by regulating autophagy and apoptosis. [TOR] (Mus musculus) PubMed

 25070.

The crystal structure of wild type RpFNR and kinetic analyses of the reaction of wild type, and Y328F, Y328H and Y328S mutants with NADP(+)/NADPH using steady state and pre-steady state kinetic approaches, is reported.[FNR] (Mus musculus) PubMed

 25071.

possibility of inhibiting the ability of different cancer cell lines to migrate under the influence of the Bacillus pumilus ribonuclease (binase) was analyzed using the scratch-wound assay [binase] (Mus musculus) PubMed

 25072.

This study reports the biochemical characterization of an alkali-moderately thermophilic tannase from Lactobacillus pentosus BA-7. [alkaline tannase] (Mus musculus) PubMed

 25073.

Hemoglobin in Arthropods-Daphnia as a Model [Hb] (Mus musculus) PubMed

 25074.

The purified recombinant putrescine monooxygenase from Shewanella putrefaciens showed Flavin-Adenine Dinucleotide and NADPH dependent N-hydroxylation activity. [putrescine monooxygenase] (Mus musculus) PubMed

 25075.

Ergosterol biosynthesis is a classic target for antifungals, and squalene synthase (SQS) catalyzes the first committed step in ergosterol biosynthesis. Squalene synthase from the pathogen Aspergillus flavus was expressed and characterized. [Squalene synthase] (Mus musculus) PubMed

 25076.

the hyperactivation of microbe-associated molecular patterns-triggered immune responses confers BSR1-mediated robust resistance to broad-spectrum pathogens.[BSR1] (Mus musculus) PubMed

 25077.

a comparative morpho-physiological and proteomics analysis approach to monitor the changes in germinating seeds of two incongruent (drought-sensitive wild-type Vp16 and drought-tolerant mutant vp16) lines exposed to polyethylene-glycol-induced drought stress, is reported.[vp16] (Mus musculus) PubMed

 25078.

Betweenness centrality (BC) profiles for PfHsp70-1 and PfHsp70-x derived from CG simulations not only revealed similar trends but also pointed to the same functional regions and specific residues corresponding to BC profile peaks.[PfHsp70-1, PfHsp70-x] (Mus musculus) PubMed

 25079.

OsMSR3 expression in A. thaliana increased the expression of antioxidant-related and abscissic acid-responsive genes.[OsMSR3] (Mus musculus) PubMed

 25080.

Constitutively active Ras1 leads to the repression of impa1 and impa2 transcription.[Ras1. impa1 and impa2] (Mus musculus) PubMed

 25081.

proteolysis mediated by the membrane-integrated ATP-dependent protease FtsH has a unique nonlinear dependence on ATP hydrolysis rates [FtsH] (Mus musculus) PubMed

 25082.

The present approach was used to reveal the substrate binding mechanism of AtuUdh mutants for a better understanding of the structural basis for selectivity and function.[AtuUdh] (Mus musculus) PubMed

 25083.

The purified HgdA protein had UDP-galactose 4-epimerase activity in vitro. This enzyme could be responsible for synthesis of heterocyst-specific glycolipid precursors, which could be transported over the cell wall by the ABC transporter components HgdB/HgdC.[HgdA] (Mus musculus) PubMed

 25084.

RavZ The effects of LIR motifs and the membrane-targeting domain on RavZ activity are complementary and work through independent pathways. (Mus musculus) PubMed

 25085.

Phylogenetic analysis indicated that RBSR1 is orthologous to the human splicing factor SRSF7, what might indicate its possible involvement in pre-RNA processing. [RBSR1] (Mus musculus) PubMed

 25086.

Isolated and characterized is the wall-associated kinase 6 encoding gene in wheat, and assigned it as TaWAK6. It is proposed that TaWAK6, which is a non-arginine-aspartate (non-RD) kinase, represents a novel class of quantitative immune receptors in monocots. [TaWAK6] (Mus musculus) PubMed

 25087.

Examination of the nucleotide-linked assembly mechanism of E. coli ClpA [ClpA] (Mus musculus) PubMed

 25088.

Cryoelectron microscopy structures of AdnAB reveal the path of the 5' single-stranded DNA through the AdnA nuclease domain and the mechanism of 5' strand cleavage; the path of the 3' tracking strand through the AdnB motor and the DNA contacts that couple ATP hydrolysis.[AdnAB] (Mus musculus) PubMed

 25089.

Deletion of FgPEX1 and FgPEX10 resulted in reduced mycelial growth, conidiation, and production of perithecia, a shortage of acetyl-CoA, which is an important reason for the reduced deoxynivalenol production and inhibited virulence of F. graminearum. Moreover, DeltaPEX1 and DeltaPEX10 showed an increased accumulation of lipid droplets and endogenous reactive oxygen species. (FgPEX10,FgPEX1) (Mus musculus) PubMed

 25090.

The data support a model whereby GlnK uridylylation is not necessary to activate NifA. On the other hand, binding of 2-OG and MgATP to GlnK are very important for NifA activation and constitute the most important signal of cellular nitrogen status to NifA (GlnK). (Mus musculus) PubMed

 25091.

Citrus Cs-UGT78D3 gene contributes to proanthocyanidins accumulation in seed coats and confers tolerance to high light stress by accumulating the total anthocyanin and flavonoid contents with better antioxidant potential (due to photoprotective activity of anthocyanin) in the transgenic Arabidopsis. [UGT78D3] (Mus musculus) PubMed

 25092.

RpoZ variants and its role in the biofilm production and selection pressure in the isolates from China.RpoZ variants correlate with colder and drier climates[RpoZ] (Mus musculus) PubMed

 25093.

ICP27 blocks transcription termination of host genes by inhibiting mRNA 3' processing.ICP27 activates viral mRNA 3' processing.A critical role for ICP27 in mediating host shut-off during HSV-1 infection.[ICP27] (Mus musculus) PubMed

 25094.

Loss of the negative cofactor 2 complex[AFUB_029870 (NctA) and AFUB_045980 (NctB)] leads to resistance. [NctA, NctB] (Mus musculus) PubMed

 25095.

study discovered the plasmanylethanolamine desaturase activity that is essential for vinyl ether bond formation in a bacterial enzyme, CarF, which is a homolog of the human enzyme TMEM189; CarF mediates light-induced carotenogenesis [CarF] (Mus musculus) PubMed

 25096.

Mechanism of forked dsDNA unwinding by Pif1 helicase.The binding of Pif1 to the 5' arm causes a sharp bend in the 5' ss/dsDNA junction, consequently breaking the first base-pair.Pif1 bound to the 3' ss/dsDNA junction impacts duplex unwinding by stabilizing the unpaired first base-pair and engaging the second base-pair poised for breaking.[Pif1] (Mus musculus) PubMed

 25097.

The gastric secretory trefoil factor family (TFF) peptides xP1 and xP4 are the Xenopus laevis orthologs of mammalian TFF1 and TFF2, respectively. (Mus musculus) PubMed

 25098.

Structural comparison with IF4G homologs from other eukaryotes and other MIF4G-containing proteins reveals differences that may account for the specific interaction mechanisms of MIF4G despite its highly conserved overall fold[MIF4G] (Mus musculus) PubMed

 25099.

Studies on the alpha-carboxysome from Halothiobacillus neapolitanus demonstrate that Rubisco interacts with the N terminus of CsoS2, a multivalent, intrinsically disordered protein. [CsoS2] (Mus musculus) PubMed

 25100.

Two EF-hand motif-containing proteins, TgGT1_216620 and TgGT1_280480, localize to the plasma membrane and to the rhoptry bulb, respectively. Genetic disruption of these genes by CRISPR/Cas9 resulted in mutant parasite clones (Deltatg216620 and Deltatg280480) that grew at a slower rate than control cells. [TgGT1_216620, TgGT1_280480] (Mus musculus) PubMed

 25101.

Cdc15 facilitates Cdc42 activation at the division site during cytokinesis at the cell cortex to promote bipolarity and this is mediated by promoting Gef1 localization to these sites.[Cdc15, Cdc42] (Mus musculus) PubMed

 25102.

Knockdown of CHSB in the larval stage significantly lowered the chitin content, decreased body size in the larval stage and in the adult stage, and diminished reproduction.[CHSB] (Mus musculus) PubMed

 25103.

Starvation-induced remodeling is also dependent on neuroligin/nlg-1, the canonical binding partner for neurexin/nrx-1, and the transcription factors FOXO/daf-16 and HSF1/hsf-1 hsf-1 and daf-16.[Nrx-1] (Mus musculus) PubMed

 25104.

by following individual ClpB-substrate complexes in real time, we unambiguously demonstrate processive translocation of looped polypeptides; integration of optical tweezers with fluorescent-particle tracking shows that ClpB translocates both arms of the loop simultaneously and switches to single-arm translocation when encountering obstacles (Mus musculus) PubMed

 25105.

pre-piRNAs are generated by parallel Zucchini-dependent and -independent mechanisms; cleavage by Zucchini occurs at previously unrecognized consensus motifs on pre-pre-piRNAs, requires the RNA helicase Armitage, and is accompanied by 2'-O-methylation of pre-piRNAs [zucchini] (Mus musculus) PubMed

 25106.

Cad is expressed in larval and adult midgut-specific manner and its expression pattern changed during the mosquito development.[Cad] (Mus musculus) PubMed

 25107.

OsSPL10 negatively controls salt tolerance but positively controls trichome formation in rice.[OsSPL10] (Mus musculus) PubMed

 25108.

distinct interactions of UapA with membrane lipids are essential for ab initio formation of functional dimers in the endoplasmic reticulum (ER), or ER exit and further subcellular trafficking.[UapA] (Mus musculus) PubMed

 25109.

single nucleotide substitution at 5'-UTR of GSN1 represses its translation and leads to an increase of grain length in rice [GSN!] (Mus musculus) PubMed

 25110.

In this study, the authors found that the Thermococcus sp. 4557 DP1 (small subunit of PolD) interacted with GINS15 in vitro, and the 3'-5' exonuclease activity of DP1 was inhibited by GINS15. They also demonstrated that the GAN, GINS15, and DP1 proteins interact to form a complex adapting a GAN-GINS15-DP1 order.[GAN, GINS15, DP1] (Mus musculus) PubMed

 25111.

The 24-h root inoculation with the three plant growth-promoting bacteria strains increased the nuclei population in the G1 and S phases, decreased it in the G2 phase and enhanced the WUSCHEL-related Homeobox5 (WOX5) gene expression in root tips and lateral zones.[WOX5] (Mus musculus) PubMed

 25112.

For the first time, the authors demonstrated the mechanism of merA regulation in a cyanobacterium, Synechocystis. Although merA and merR genes are distantly located on the cyanobacterial genome and distinct from other bacterial mer-operons, the transcriptional regulatory mechanism is conserved.[merA, merR] (Mus musculus) PubMed

 25113.

Processing body (PB) component Pat1 antagonizes Not1 and promotes PB assembly via its direct interaction with Dhh1.[Pat1, Dhh1] (Mus musculus) PubMed

 25114.

a fungal scramblase from Aspergillus fumigatus, afTMEM16, reconstituted in lipid nanodiscs, is reported.[TMEM16] (Mus musculus) PubMed

 25115.

The S68G polymorphism in the HIV-1 reverse transcriptase may be a natural polymorphism and compensatory mutation of K65R selected by reverse transcriptase inhibitors in the CRF01_AE strain of HIV-1. [reverse transcriptase] (Mus musculus) PubMed

 25116.

In contrast to rad24, mutants defective in the ATR kinase homolog Mec1, including a mec1 null and a mec1 kinase-dead mutant, show slight or few defects in crossover frequency.[Rad17, Mec1] (Mus musculus) PubMed

 25117.

This is the first study to reveal that Cd exposure induces immunotoxicity through miR-155 and miR-181a in the kidneys of C. carpio [miR-155; miR-181a]. (Mus musculus) PubMed

 25118.

lncRNA SLC8A1-AS1, by downregulating SLC8A1 and activating the cGMP-PKG signaling pathway, inhibits the release of proinflammatory factors and reduces infarct size in mouse model of myocardial infarction. (Mus musculus) PubMed

 25119.

Machi3-1 protein could partially protect 5B-Machi3-1 allele containing cultivars against Erwinia by inhibiting the multiplication and biofilm formation of the pathogen in the stigma exudate and in the nectar.[Machi3-1] (Mus musculus) PubMed

 25120.

This study identified a new beta-lactamase CTX-M gene in Pathogenicity Island III536of Escherichia coli.[blaCTX-M] (Mus musculus) PubMed

 25121.

The influenza B M2 (BM2) proton channel is activated by acidic pH to mediate virus uncoating. This study reports 1.4- and 1.5-A solid-state NMR structures of the transmembrane domain of the closed and open BM2 channels in a phospholipid environment. [BM2 proton channel] (Mus musculus) PubMed

 25122.

aerE is an aeruginoside biosynthesis isomerase. [aerE] (Mus musculus) PubMed

 25123.

Fpr3 and Fpr4 operate separately, cooperatively, and redundantly to regulate a variety of chromatin environments.[Fpr3, Fpr4] (Mus musculus) PubMed

 25124.

rmtA was dispensable for virulence, however forced overexpression of rmtA increased mortality with respect to the wild type.[rmtA] (Mus musculus) PubMed

 25125.

Infection with LdeK1-dominant-negative mutation L donovani parasites resulted in significantly fewer regulatory T cells and T2 helper cells and less parasite loads in spleen and liver in the susceptible BALB/c mice. Parasites lacking a functional LdeK1 reduce loss of infectivity of by modulating the immune response towards host protection. [LdeK1] (Mus musculus) PubMed

 25126.

The inhibition of Irm blocks damage-induced muscle regeneration in vivo. Mechanistically, Irm regulates the expression of myogenic genes by directly binding to MEF2D, which in turn promotes the assembly of MyoD/MEF2D on the regulatory elements of target genes (lncRNA Irm). (Mus musculus) PubMed

 25127.

TgpA is an internal membrane protein with a periplasmic soluble domain, predicted to be endowed with a transglutaminase-like fold, hosting the Cys404, His448, and Asp464 triad, and essential for P. aeruginosa viability. [TgpA] (Mus musculus) PubMed

 25128.

we described the identification and functional characterization of a MAp44 homologue (OnMAp44) from Nile tilapia (Oreochromis niloticus) at molecular, cellular and protein levels (Mus musculus) PubMed

 25129.

PGC-1b modulated the cell differentiation and triglyceride accumulation in chicken adipocytes. (Mus musculus) PubMed

 25130.

Transgenic tobacco plants expressing OsHsp17.4 and OsHsp17.9A proteins and Arabidopsis plants ectopically expressing OsHsp17.4 protein showed improved thermotolerance.[OsHsp17.4, OsHsp17.9A] (Mus musculus) PubMed

 25131.

Segregation analysis of the F2 population showed that the hemisugary phenotype was controlled by a single recessive gene, which was produced by a G --> A single nucleotide polymorphism in the sugary-1 gene [sugary-1] (Mus musculus) PubMed

 25132.

The study reports the structure-guided design of a xylose-releasing exo-beta-1,4-xylanase from an inactive member of glycoside hydrolase family 43 (GH43). Structural analysis revealed a nonconserved substitution (Lys(247) ) that results in the disruption of the hydrogen bond network that supports catalysis. [exo-beta-1,4-xylanase] (Mus musculus) PubMed

 25133.

the identification of regulator of cell death-1 (rcd-1), a novel allorecognition gene, controlling programmed cell death in germinating asexual spores of Neurospora crassa, is reported.[rcd-1] (Mus musculus) PubMed

 25134.

Secreted parasite Pin1 isomerase stabilizes host PKM2 to reprogram host cell metabolism. [Pin1] (Mus musculus) PubMed

 25135.

2 paralogous Legionella effectors, DupA and DupB, reverse PR-ubiquitination by specific removal of phosphoribosyl-Ub from substrates. Both DupA and DupB are fully capable of rescuing the Golgi fragmentation phenotype caused by exogenous expression of SdeA in mammalian cells. DupA and DupB play a role in modulating the association of PR-ubiquitinated host targets with Legionella-containing vacuoles. DupA. DupB. (Mus musculus) PubMed

 25136.

Results suggest that PfTLR26 may be an important component of the P. fulvidraco innate immune system, participating in the transduction of TLR signaling under pathogen stimulation [TLR26]. (Mus musculus) PubMed

 25137.

First, the authors show that the Enterococcus faecalis secreted enzyme gelatinase (GelE) is responsible for cleaving EntV into its 68-amino-acid, active form and that this process does not require the serine protease SprE. Furthermore, they demonstrate that a disulfide bond that forms within EntV is necessary for antifungal activity.[EntV] (Mus musculus) PubMed

 25138.

The authors found that each AdeB molecule within the trimer preferentially takes the resting conformational state in the absence of substrates.[AdeB] (Mus musculus) PubMed

 25139.

Pgp3 has d,d-carboxy- and d,d-endopeptidase activities.Pgp3 crystal structure reveals domain architecture.[Pgp3] (Mus musculus) PubMed

 25140.

Study shows that speed, fidelity, and undefined biochemical properties of the RdRp exist and contribute to both the mechanism and efficiency of recombination. This inextricable connection of the myriad biochemical properties of the RdRp precludes attribution of a single biochemical property to viral fitness, virulence, and pathogenesis. [RdRp] (Mus musculus) PubMed

 25141.

GreA and Gfh1 modulate DNA damage sensing by Deinococcus radiodurans RNA polymerase. [GreA]; [Gfh1] (Mus musculus) PubMed

 25142.

CRN is involved in the same signaling pathway as MtCLE12p and MtCLE13p, while regulation in CRA2 mutants responds normally to the peptides, suggesting CRA2 likely signals separately from SUNN, RDN1, and CRN.[MtCLE12p, MtCLE13p, CRN, CRA2] (Mus musculus) PubMed

 25143.

This study reports the cryo-EM structures of the Escherichia coli RecBCD complex bound to several different DNA forks containing a Chi sequence, including one in which Chi is recognized and others in which it is not. [RecB, RecC, RecD] (Mus musculus) PubMed

 25144.

FlgX acts as a chaperone for C. jejuni stator units to ensure sufficient power and torque for flagellar rotation and motility.[FlgX] (Mus musculus) PubMed

 25145.

CT339 is identified as a ComEC Homolog Important for DNA Uptake and Lateral Gene Transfer. [ComEC] (Mus musculus) PubMed

 25146.

ArlRS is a metabolic sensor that allows S. aureus to integrate multiple environmental stresses that alter glycolytic flux to coordinate an antihost response and to adapt to manganese starvation.[ArlR, ArlS] (Mus musculus) PubMed

 25147.

CRT is functionally linked to protein digestion within the parasite lysosome-like organelle and that this transporter is necessary to sustain chronic infection in culture and in experimentally infected mice. [CRT] (Mus musculus) PubMed

 25148.

Agr-negative methicillin-resistant S. aureus (MRSA) isolate could reproducibly generate Agr-revertant colonies with a poly(A) tract genetic mechanism.[Agr] (Mus musculus) PubMed

 25149.

A Gly737 to Glu substitution occurring in the C-terminus of the SiSTL1 protein slightly affected its optimal function, leading in turn to the reduced expression of genes variously involved in the assembly and activation of the DNA pre-replicative complex, elongation of replication forks and S phase entry (SiSTL1). (Mus musculus) PubMed

 25150.

ZmANN33 and ZmANN35 play essential roles in membrane recovery during maize seed germination. [ANN33;ANN35] (Mus musculus) PubMed

 25151.

miR-138-5p is involved in the mitochondrial apoptosis pathway via targeting SelM in chicken chondrocytes. [miR-138-5p] (Mus musculus) PubMed

 25152.

The results suggest that Ca2+ binding to the Peptidoglycan hydrolase of bacteriophage T5 (EndoT5) molecule could be essential for the stabilization of the long mobile loop in the catalytically active "open" conformation. [peptidoglycan hydrolase] (Mus musculus) PubMed

 25153.

This study concluded that prohibitin is an autoantigen that cross-reacts with H1N1 influenza virus hemagglutinin. [hemagglutinin] (Mus musculus) PubMed

 25154.

Collectively, the authors demonstrated that annexin II is one of the host factor involved in DENV2 binding on Vero cells.[annexin II] (Mus musculus) PubMed

 25155.

Results suggest that Lnc-AK045490 suppresses beta-catenin/TCF1/Runx2 signaling and inhibits osteoblast differentiation and bone formation. (Mus musculus) PubMed

 25156.

Evidence that the Ppd gene, a major determinant of photoperiod sensitivity and broad adaptation in common bean, encodes a phytochrome A photoreceptor, PHYA3 (PHYA3). (Mus musculus) PubMed

 25157.

Cti expression was repressed by the cyclic-AMP receptor protein (Crp) and repression required the cyclic-AMP ligand of Crp. [Cti] (Mus musculus) PubMed

 25158.

This study highlights CT229 as a master regulator of multiple host vesicular trafficking pathways essential for chlamydial infection. (Mus musculus) PubMed

 25159.

SlaB trimers support the outer porous canopy of the S-layer, which is formed by an array of tightly interwoven boomerang-shaped SlaA dimers.[SlaA] (Mus musculus) PubMed

 25160.

This study shows that miR-30a-5p can inhibit duck enteritis virus replication through reducing autophagy by targeting Beclin-1.[miR-30a-5p] (Mus musculus) PubMed

 25161.

This study was performed to identify the telomerase RNA-binding domain (TRBD)-interacting protein in G. duodenalis and its regulation of telomerase [TRBD]. (Mus musculus) PubMed

 25162.

The Xanthine oxidase (XO) was homodimer of 95kDa with a molecular mass of 190kDa and was stable at 35 degrees C. [XO] (Mus musculus) PubMed

 25163.

Deletion of anvM altered the expression levels of more than 700 genes under aerobic and anaerobic conditions, including quorum sensing system genes and oxidative stress resistance genes [anvM]. (Mus musculus) PubMed

 25164.

Here, we describe the identification and characterization of a novel Dephospho-coenzyme A (dephospho-CoA) kinase (DPCK), encoded by the TK1697 gene. Orthologs of TK1697 are widely distributed in archaea, suggesting that this form of DPCK is responsible for the last step of CoA biosynthesis in most of the archaea [DPCK]. (Mus musculus) PubMed

 25165.

Determined is the crystal structure of DR0053 at 2.07A resolution. DR0053 adopted a typical four-helix bundle structure that is characteristic of DinB/YfiT proteins. [DR0053] (Mus musculus) PubMed

 25166.

Trypanosoma cruzi actin 2 (TcAct2) is expressed in all stages of the parasite. Trypanosoma cruzi TcAct1 and TcAct2 have distinct subcellular distributions. [actin 2] (Mus musculus) PubMed

 25167.

Citrus yellow vein clearing virus coat protein (CP) interacts with all three triple gene block proteins (TGB) proteins, and TGBp1 and TGBp2 interact with each other but not with TGBp3. The authors also show that CP is a strong RNA silencing suppressor.[CP, TGBp1, TGBp2, TGBp3] (Mus musculus) PubMed

 25168.

Parasites lacking the catalytic subunit of protein kinase A (PfPKAc) show severely reduced growth after one intraerythrocytic growth cycle and are deficient in host cell invasion.[PfPKAc] (Mus musculus) PubMed

 25169.

incubation of the pdxB strain in medium containing glucose as a sole carbon source for 10 d resulted in visible turbidity[pdxB] (Mus musculus) PubMed

 25170.

Our results show that mutations in prolyl isomerase I gene (PIN1) are widespread in drug-resistant parasites [PIN1]. (Mus musculus) PubMed

 25171.

Study reports the role of OsmiR528 and its target, OsUCL23 (Os08g04310, encoding a member of the uclacyanin family), in regulating pollen intine development and thus the seed-setting rate in rice. OsmiR528 affects pollen development by directly targeting OsUCL23 at the binucleate pollen stage. [MIR528] (Mus musculus) PubMed

 25172.

The MamM C-terminal domain is rather dynamic in its apo form. 2 dependent metal-binding sites, a single central binding site and 2 symmetrical, peripheral sites, are available for metal binding.However, only cation binding to the peripheral sites leads to conformational changes that lock the protein in a compact state. (Mus musculus) PubMed

 25173.

the transport routes and cellular distribution of albumin, were investigated.[Albumin] (Mus musculus) PubMed

 25174.

crystal structure of AcrR from Mycobacterium tuberculosis reveals a one-component transcriptional regulation mechanism [AcrR] (Mus musculus) PubMed

 25175.

The results suggest that SsSvf1 is involved in coping with reactive oxygen species during fungal-host interactions and plays a crucial role in the pathogenicity of S. sclerotiorum.[SsSvf1] (Mus musculus) PubMed

 25176.

a novel B. cinerea-specific pathogenicity-associated factor BcHBF1 (hyphal branching-related factor 1), plays an important role in hyphal branching, infection structure formation, sclerotial formation and full virulence of the pathogen.[BcHBF1] (Mus musculus) PubMed

 25177.

Mouse mammary tumor virus mutant (MMTV-SD) lacking regulatory/accessory protein Rem expression induces lower proviral load, lower incidence, and longer latency than the wild type. MMTV-SD proviruses have many G-to-A mutations on the proviral plus strand, but also C-to-T transitions within WRC motifs. Rem coexpression in transfection experiments lead to activation-induced cytidine deaminase (AID) proteasomal degradation. (Mus musculus) PubMed

 25178.

Loss-of-function mutants in chromatin-remodeling factor OsVIL2 show a phenotype with reduced number of tillers in rice. Expression of OsTB1, a negative regulator of bud outgrowth, is increased in osvil2 mutants. OsVIL2 binds to the promoter of OsTB1 chromatin in wild-type rice, but not in osvil2 mutants. Tiller number of double mutant osvil2 ostb1 is similar to that of ostb1, suggesting that osvil2 is epistatic to ostb1. (Mus musculus) PubMed

 25179.

MazEF, a toxin-antitoxin gene, inhibits biofilm formation and promotes biofilm antibiotic tolerance. [mazE,mazF] (Mus musculus) PubMed

 25180.

AGLF and SGL1 regulate floral organ identity through ABC model, but are probably involved in other pathways to control compound leaf development.[AGLF] (Mus musculus) PubMed

 25181.

XopQ targets the rice 14-3-3 mediated immune response pathway.[XopQ] (Mus musculus) PubMed

 25182.

XopQ targets the rice 14-3-3 mediated immune response pathway.[Gf14f, Gf14g, Gf14e] (Mus musculus) PubMed

 25183.

liver-specific protein 2 (LISP2) is a molecular marker of initiation of liver-stage development in relapsing malaria parasites (LISP2). (Mus musculus) PubMed

 25184.

liver-specific protein 2 (LISP2) is a molecular marker of initiation of liver-stage development in relapsing malaria parasites (LISP2). (Mus musculus) PubMed

 25185.

The region upstream of the mannose-specific adhesin (Msa) gene in the studied variants showed an inversion of a 104-bp fragment located between two perfectly inverted repeats present in the untranslated leader region. The inversion disrupts a strong hairpin structure that otherwise most likely would terminate the msa transcript. [Msa] (Mus musculus) PubMed

 25186.

The association of common intronic single-nucleotide variants in the human TRAPalpha gene with susceptibility to type 2 diabetes and pancreatic beta cell dysfunction suggests that impairment of preproinsulin translocation and proinsulin trafficking may contribute to the pathogenesis of type 2 diabetes.[Insulin] (Mus musculus) PubMed

 25187.

coilin-deficient plants and the deletion mutant of the tobacco rattle virus [TRV 16K] protein showed that both 16K and coilin are required for restriction of systemic TRV infection.[16k] (Mus musculus) PubMed

 25188.

Mutation of cneA compromised not only Ca(2+) entry, but also compromised the Hypersensitive response (HR) in tobacco leaves and blocked the ability to induce knots in olive stems.[cneA] (Mus musculus) PubMed

 25189.

the extended cleavage specificities of a rabbit beta-chymase and a guinea pig alpha-chymase, are reported.[beta chymase] (Mus musculus) PubMed

 25190.

A higher level of endogenous abscisic acid (ABA) and a higher transcript level of the ABA pathway genes in the mutant lines revealed that the PbPAT14 function was related to the ABA pathway.[PbPAT14] (Mus musculus) PubMed

 25191.

These results reveal a (redundant) role for MtSWEET1b in the transport of glucose across the peri-arbuscular membrane to maintain arbuscules for a healthy mutually beneficial symbiosis.[MtSWEET1b] (Mus musculus) PubMed

 25192.

Furthermore, molecular docking, MD simulation and site-directed mutagenesis indicate the binding cavities are located at cavity 1 in C-terminal of CSP4, where Tyr98 and Asp67 are vital amino acids in maintaining the stable form of protein and larval pheromones, and electrostatic energies are the main driving forces. (Mus musculus) PubMed

 25193.

The major determinant of temperature-regulated cnfY expression is a thermo-labile RNA structure in the 5'-untranslated region. [cnfY] (Mus musculus) PubMed

 25194.

GPA1 negatively regulates sporangium formation by repressing the nuclear localization of its downstream kinase YPK1. [YPK1, GPA1] (Mus musculus) PubMed

 25195.

p10 and p15 as novel chapparvovirus accessory proteins produced in MKPV-infected kidneys.[p10. p15] (Mus musculus) PubMed

 25196.

A novel lncRNA was widely expressed in a variety of bovine tissues with diverse relative abundance and had a low expression in mammary tissue. Its predicted target gene is TUBA1C. It plays crucial roles in the morphological shape, proliferation, migration and beta-casein secretion of mammary epithelial cells. It mediates E. coli-induced inflammatory factor secretion and S. aureus adhesion to epithelial cells. lncRNA-TUB. (Mus musculus) PubMed

 25197.

Injection of a miR-1-3p mimic in early Bactrocera dorsalis embryos results in 87-92% phenotypic males, whereas knockdown of miR-1-3p by an inhibitor results in 67-77% phenotypic females. Knockout of miR-1-3p results in the expression of female-specific splice variants of Bdtra and doublesex (Bddsx), and induced sex reversal of XY individuals into phenotypic females. (Mus musculus) PubMed

 25198.

Reverse-engineering of an unknotted circular permutant (CP) of YbeA by introducing a new opening at the knotting loop resulted CP folded into an unexpected domain-swapped dimer. Untying the knotted loop abrogated its function, perturbed its folding stability and kinetics, and induced allosteric dynamic changes.[YbeA] (Mus musculus) PubMed

 25199.

indicate that AK054386 and miR-199 are critical players in hepatic IRI, and we broadened the scope regarding ceRNA mechanisms[ AK054386] (Mus musculus) PubMed

 25200.

Our results suggest a model for V. cholerae biofilms in which Bap1 and RbmC play dominant but differing adhesive roles in biofilms, allowing bacterial attachment to diverse environmental or host surfaces. (Mus musculus) PubMed

 25201.

point mutation of OsCIPK7 led to a conformational change in the activation loop of the kinase domain, subsequently with an increase of protein kinase activity, thus conferred an increased tolerance to chilling stress.[OsCIPK7] (Mus musculus) PubMed

 25202.

Study reports the structures of Mycobacterium tuberculosis penicillin-binding protein 3 (MtbPBP3), an essential protein in M. tuberculosis, in complex with several widely used beta-lactam antibiotics (e.g., meropenem, aztreonam, and amoxicillin). These data provide new insights for next-generation rational approaches to design tuberculosis-specific beta-lactam or nonlactam antibiotics.[MtbPBP3] (Mus musculus) PubMed

 25203.

[NS7b] [NS8] Two of six nonstructural proteins, NS7b and NS8, were exclusively conserved among 2019-nCoV, BetaCoV_RaTG, and BatSARS-like Cov. (Mus musculus) PubMed

 25204.

these observations support the hypothesis that the XA21 receptor evolved specifically to recognize Xanthomonas oryzae RaxX.[XA21] (Mus musculus) PubMed

 25205.

sesquiterpene cyclase-mediated compounds participate in pre-invasive resistance to necrotrophic pathogen.[Sesquiterpene cyclase] (Mus musculus) PubMed

 25206.

Cytoplasmic retention and degradation of a mitotic inducer, CDC25, enable plant infection by a pathogenic fungus by targeting its importin, Kap123 ( CDC25, Kap123). (Mus musculus) PubMed

 25207.

The biochemical and structural characterization of recombinant trehalase from E. cloacae (Px_EclTre) showed KM of 1.47 mm, kcat of 6254.72 min(-1) and Vmax 0.2 mm.min(-1) at 55 degrees C and acidic pH. Crystal structures of Px_EclTre were determined in the ligand-free form and bound to the inhibitor Validoxylamine A.Multiple salt bridges were identified and 5 tryptophans lining the -1 substrate binding site (trehalase). (Mus musculus) PubMed

 25208.

betasatellite-encoded betaC1 protein accomplishes counter-defence by physical interaction with PsbP reducing the ability of PsbP to bind geminivirus DNA to establish infection.[betaC1] (Mus musculus) PubMed

 25209.

The functions of gpr54 in brain are not sex-specific.(GPR54) (Mus musculus) PubMed

 25210.

TcNST2 mRNA levels were detected in all T. cruzi life-cycle forms, with an increase in expression in axenic amastigotes. The transporter is specifically localized to the Golgi apparatus. A three-dimensional model of TcNST2 suggested an overall structural conservation as compared with members of the metabolite transporter superfamily and also suggested specific features that could be related to its activity. [NST2] (Mus musculus) PubMed

 25211.

Study in mouse model and patient tissue samples showed that plasmacytoid dendritic cells are recruited to the infected tissue during group A streptococcal necrotizing fasciitis. Streptococcal DNase Sda1 impairs plasmacytoid dendritic cell recruitment by reducing IFN-1 levels at the site of infection. [Sda1] (Mus musculus) PubMed

 25212.

These results revealed a new level of Ghd7 regulation by phytochromes and OsGI in photoperiodic control of flowering in rice.[Ghd7, OsGI] (Mus musculus) PubMed

 25213.

MdBT2 interacted physically with MdWRKY40 and was involved in its degradation through the 26S proteasome pathway.[MdWRKY40, MdMYB1, MdBT2] (Mus musculus) PubMed

 25214.

This study identifies a novel regulator of fatty acid metabolism TfmR, and suggests that fatty acids play an important role in the metabolic control of virulence in Xanthomonas citri.[TfmR] (Mus musculus) PubMed

 25215.

asparagine residues at the 238 and 391 positions of KatG2 could be modified by N-glycosylation and that these two residues are required for KatG2 accumulation and cell wall localization in planta.[KatG2] (Mus musculus) PubMed

 25216.

This work demonstrates the conserved and novel roles of the miR164-CUC2 module in leaf and flower development in different plant species, and reveals that the 19(th) nucleotide of FvemiR164a is important for its processing.[miR164, CUC2] (Mus musculus) PubMed

 25217.

reveals structural peculiarities at the transmembrane region of IrtAB that result in a partially collapsed inward-facing substrate-binding cavity[IrtA and IrtB] (Mus musculus) PubMed

 25218.

V. cholerae IbaG controls cell morphology and cell envelope integrity through its role in biogenesis or trafficking of iron-sulfur cluster proteins. [IbaG]. (Mus musculus) PubMed

 25219.

Under replicating conditions, the tricyclic 4-hydroxyquinolines and a barbituric acid analogue deplete intrabacterial magnesium, and mutations in CorA, a putative Mg2+/Co2+ transporter, conferred resistance to the compounds [CorA]. (Mus musculus) PubMed

 25220.

We find that RON3 is required for the protein transport function of the Plasmodium translocon of exported proteins and for glucose transport from the red blood cell cytoplasm to the parasite [RON3]. (Mus musculus) PubMed

 25221.

support a model in which the nucleus is connected to cytoskeletal F-actin through the ARM-domain, predicted alpha solenoid structure of MLKS2 [MLKS2] (Mus musculus) PubMed

 25222.

Of the predicted protein-coding genes, Amuc_1434, which encodes for a hypothetical protein, is the focus in this study. Amuc_1434* is identified as a member of the aspartic protease family through the action of inhibitor pepstatin A. Amuc_1434* promotes the adhesion of colon cancer cell line LS174T, which can highly express Muc2. Amuc_1434* can degrade Muc2 of colon cancer cells.[Aspartic Protease] (Mus musculus) PubMed

 25223.

These results suggest that chitin deacetylase 3 might play an important role in the immune response of D. citri. [chitin deacetylase 3] (Mus musculus) PubMed

 25224.

Sho1, a homolog of the Saccharomyces cerevisiae Sho1, acts as an osmosensor, and is required for plant penetration and melanin biosynthesis. [Sho1] (Mus musculus) PubMed

 25225.

Crl stabilizes key structural motifs within sigma(S)2 to promote the assembly of the sigma(S)-RNAP holoenzyme and also to facilitate formation of an RNA polymerase-promoter DNA open complex.[Crl, sigma factor] (Mus musculus) PubMed

 25226.

Study identified BAZ2B as a major interactant of small hepatitis delta virus (HDV) antigen (S-HDAg) in human hepatocytes. BAZ2B bromodomain, which generally binds the K14acXXR motif in histone H3-tail, recognizes the same K72acXXR motif in S-HDAg. S-HDAg mimics histone H3 acetylation to recruit BAZ2B-associated remodeling factor complexes and RNA Pol II on the HDV ribonucleoproteins to sustain HDV replication.[S-HDAg] (Mus musculus) PubMed

 25227.

Here, the authors show that Shigella flexneri invasion plasmid antigen H (IpaH) 4.5, a member of the E3 ubiquitin ligase effector family, targets the proteasome regulatory particle non-ATPase 13 (RPN13) and induces its degradation via the ubiquitin-proteasome system (UPS).[IpaH4.5] (Mus musculus) PubMed

 25228.

deficiency exacerbates cardiac fibrosis via miR-214-3p/NLRC5 axis - [miR-214-3p] (Mus musculus) PubMed

 25229.

StuA is indispensable for A. oligospora trap formation and virulence. [StuA] (Mus musculus) PubMed

 25230.

Collectively, TgACBP1 and TgSCP2 play synergistic roles in lipid metabolism in Toxoplasma gondii.[ACBP1] (Mus musculus) PubMed

 25231.

two pathways act in concert to protect cyclin B from Cdc20-activated APC/C in G2, in order to enable cyclin B accumulation and the G2-to-M transition.[Cyclin B] (Mus musculus) PubMed

 25232.

Three HWE kinase genes that collectively control general stress response: gsrK and lovK are activators, while gsrP is a repressor. [gsrK, lovK, gsrP] (Mus musculus) PubMed

 25233.

The 2.2-A crystal structure of the MoxR AAA+ protein CbbQ2 from Acidithiobacillus ferrooxidans reveals the helix 2 insert (H2I) that is critical for Rubisco activase function and forms the axial pore of the CbbQ hexamer. Essential CbbO adaptor protein binds to the conserved, concave side of the CbbQ2 hexamer. [CbbQ2] (Mus musculus) PubMed

 25234.

Findings suggest that conformational fluctuations are an inherent property of AlkB catalysis, and that the enzyme-substrate complex with ssDNA is more flexible and undergoes more conformational transitions than that of dsDNA. [AlkB] (Mus musculus) PubMed

 25235.

GTP Preference of d-Glycero-alpha-d-manno-Heptose-1-Phosphate Guanylyltransferase from Yersinia pseudotuberculosis. (Mus musculus) PubMed

 25236.

protease activity assay for investigating the functions of the Escherichia coli membrane protease HtpX [HtpX] (Mus musculus) PubMed

 25237.

The putative formation of phenylglyoxal-arginine adducts, and the consequent spatial rearrangement in the enzyme structure, inhibits the F1FO-ATPase activity but, as shown by the calcium retention capacity evaluation in intact mitochondria, apparently favours the mitochondrial permeability transition pore (mPTP) formation. [mPTP] (Mus musculus) PubMed

 25238.

results suggest a novel mechanism of LIS1 action that promotes the switch of dynein from the autoinhibited state to an open state to facilitate dynein activation [LIS1] (Mus musculus) PubMed

 25239.

Here, the authors show that Salmonella typhi STIV interacts with receptor tyrosine kinase, Met, of host intestinal epithelial cells. This interaction leads to Met phosphorylation and activation of a downstream signalling cascade, involving Src, phosphatidylinositol 3-kinase/Akt, and Rac1, which culminates into localized actin polymerisation and bacterial engulfment by the cell.[STIV] (Mus musculus) PubMed

 25240.

The activity of SigM is regulated by its anti-sigma factor, YhdL, and the accessory protein YhdK.[ YhdL, YhdK] (Mus musculus) PubMed

 25241.

YjbH and ClpXP proteolytically cleave Spx, a repressor of cspA transcription, to affect sigma(B) -dependent carotenoid expression.[YjbH] (Mus musculus) PubMed

 25242.

Myxovirescin A is converted to its glucoside derivative by the GTase YjiC from B. licheniformis J32. [YjiC] (Mus musculus) PubMed

 25243.

Our analysis substantiated high evolutionary changes in VP8* of the P[8], P[4], and P[6] major RV strains and their increasing variations from the candidate subunit vaccine strains over time [VP8]. (Mus musculus) PubMed

 25244.

Trypanosoma cruzi immunoproteome: Calpain-like CAP5.5 differentially detected throughout distinct stages of human Chagas disease cardiomyopathy. (Mus musculus) PubMed

 25245.

that DGCR5 is a tumor-suppressive lncRNA that regulates PTEN and BTG1 expression through directly binding to miR-23b (Mus musculus) PubMed

 25246.

This study identified and characterized ChlreSEX4, a C. reinhardtti glucan phosphatase. ChlreSEX4 binds and dephosphorylates amylopectin in vitro. Cys224 and Trp305 residues are critical for substrate binding and catalytic activity. [ChlreSEX4] (Mus musculus) PubMed

 25247.

This study presents the crystal structure of levansucrase in complex with levanbiose. [levansucrase] (Mus musculus) PubMed

 25248.

The Na(+)-translocating (NQR)-deficient strain, but not the H(+)-translocating (NDH-1)-deficient one, exhibited impaired growth characteristics under diazotrophic condition, suggesting a role for the Na(+) transport in nitrogen fixation by A. vinelandii. [NQR, NDH-1] (Mus musculus) PubMed

 25249.

Streptomyces IHF uses multiple interfaces to bind DNA. (Mus musculus) PubMed

 25250.

Design of a light-gated proton channel based on the crystal structure of Coccomyxa rhodopsin. (Mus musculus) PubMed

 25251.

The authors suggest that miR-29b-3p might regulate anti-apoptotic survival mechanisms in central nervous system areas that are not affected by neurodegeneration in the wobbler mouse amyotrophic lateral sclerosis model. (Mus musculus) PubMed

 25252.

The authors show that the hemoglobin uptake process in Cryptococcus neoformans involves clathrin heavy chain, Chc1, which appears to colocalise with hemoglobin-containing vesicles and to potentially assist in proper delivery of hemoglobin to the vacuole.[Chc1] (Mus musculus) PubMed

 25253.

Flavones and flavonols had potent inhibitory effects on YbeY.[YbeY] (Mus musculus) PubMed

 25254.

Helicobacter pylori possess only one OASS (hp0107) gene and we showed that the protein coded by this gene actually functions as an OCBS and utilizes L-homocysteine and O-acetylserine (OAS) to produce cystathionine.[CBS] (Mus musculus) PubMed

 25255.

eletion of TtcA, a hybrid polyketide synthase (PKS)-nonribosomal peptide synthase (NRPS), abolished production of all triticones. [TtcA, NRPS] (Mus musculus) PubMed

 25256.

AcuA and CobB modulate the level of Acs activity in S. aureus.[Acs, CobB] (Mus musculus) PubMed

 25257.

The authors propose that the IE86 protein utilizes different regions to regulate the Type I Interferon pathway: aa 136-289 to promote STING (Stimulator of Interferon Genes) degradation and the two transactivation domains to block cellular transcription factors for Interferon Beta promoter activation. (Mus musculus) PubMed

 25258.

Using BPtpA from the opportunistic pathogen Burkholderia cenocepacia, as a representative member of the Low molecular weight protein tyrosine phosphatases (LMW-PTP) class II.I, this study demonstrated that four conserved residues (W47, H48, D80, and F81) are required for enzyme function. [BPtpA] (Mus musculus) PubMed

 25259.

STEMIN1 functions within an intrinsic mechanism underlying local H3K27me3 reprogramming to initiate stem cell formation.[STEMIN1] (Mus musculus) PubMed

 25260.

a lysine de-2-hydroxyisobutyrylation-mediated molecular mechanism that is catalyzed by CobB, is reported.[CobB] (Mus musculus) PubMed

 25261.

Complement-interfering protein CIP can also interact with human C3, C3b, and C3d. CIP binding to C3d interferes with the interaction between C3d and the CR2/CD21 receptor on B cells, downregulating their activation. The CIP domain involved in C3d binding was mapped via hydrogen deuterium exchange-mass spectrometry. CIP plays a role at the interface between the innate and adaptive immune responses. CIP. (Mus musculus) PubMed

 25262.

At the parasite's surface, JNK2 forms a complex with p104, a GPI-(GlycosylPhosphatidylInositol)-anchor Theileria annulata plasma membrane protein. Theileria annulata sequestration of JNK2 contributes to both survival and dissemination of Theileria-transformed macrophages.[P104] (Mus musculus) PubMed

 25263.

XC_0706 and XC_3001 are annotated as the lytic transglycosylases and are associated with virulence and plays a pivotal role in cell division.[XC_0706 and XC_3001] (Mus musculus) PubMed

 25264.

These data provides insight into how Has1 performs its separate functions in the synthesis of both ribosomal subunits.[Has1] (Mus musculus) PubMed

 25265.

Rad53 phosphorylation is controlled by PP4 during the repair of a DNA lesion.[PP4] (Mus musculus) PubMed

 25266.

the crystal structures of the apo and S-adenosyl-L-methionine bound forms of Trm7-Trm734, were solved.[trm7, Trm734] (Mus musculus) PubMed

 25267.

conserved determinant in the CtrA primary structure dictates promoter reprogramming during the growth transition in other alpha-proteobacteria that differentiate from replicative cells into dispersal cells.[CtrA] (Mus musculus) PubMed

 25268.

Organophosphate hydrolase (OPH) interacts with Ton components and is targeted to the membrane only in the presence of the ExbB/ExbD complex. [OPH] (Mus musculus) PubMed

 25269.

weak interaction between phytochromes Agp1 and Agp2 from Agrobacterium fabrum [Agp1][Agp2] (Mus musculus) PubMed

 25270.

DnaA regulated the expression of NurR. [NurR] (Mus musculus) PubMed

 25271.

Prp5 RecA-like domains undergo a large conformational rearrangement only in response to binding of both ATP and RNA.[Prp5] (Mus musculus) PubMed

 25272.

These results lead to a model in which the Hrd1 channel is regulated by cycles of autoubiquitination and deubiquitination, reactions that are modulated by the other components of the Hrd1 complex.[Hrd1] (Mus musculus) PubMed

 25273.

the PPK-3-SLC-36.1 axis plays a central role in both phagocytic and autophagic lysosome formation.[PPK-3, SLC-36.1] (Mus musculus) PubMed

 25274.

SGEF plays a key role in coordinating junctional assembly and actomyosin contractility by bringing together Scribble and Dlg1 and targeting RhoG activation to cell-cell junctions.[Dlg1] (Mus musculus) PubMed

 25275.

Genetic deletion of sspA, but not of hexA, led to lack of peroxisomal localization at septal pores, suggesting that SspA is a key factor for septal pore functioning [SspA]. (Mus musculus) PubMed

 25276.

We propose that Mnn9p is a mannosyltransferase responsible for the formation of the alpha-mannan in cell wall mannoproteins, potentially via elongation of O-linked mannose chains [Mnn9p]. (Mus musculus) PubMed

 25277.

The authors' findings suggest that TaBT1 has an important effect on starch synthesis and thousand kernel weight, and provide two valuable molecular markers for marker assisted selection in wheat high-yield breeding. [TB1] (Mus musculus) PubMed

 25278.

Our data indicate that type I and II PRMTs in Aspergillus seem to co-regulate the same biological processes but also specifically affect other pathways in a non-redundant fashion [PRMT1]. (Mus musculus) PubMed

 25279.

SutA comprises a central alpha-helix with unstructured N- and C-terminal tails, and binds to the beta1 domain of RNA polymerase.[SutA] (Mus musculus) PubMed

 25280.

These studies describe the relationship between function, structure, and molecular motions in improperly regulated Rad50.[Rad50] (Mus musculus) PubMed

 25281.

In an attempt to shed light on the biochemical function of E. coli YejG, the study solved its structure using multinuclear solution NMR spectroscopy. The structure most closely resembles that of domain III from elongation factor G (EF-G). EF-G catalyzes ribosomal translocation and mutations in EF-G have also been associated with aminoglycoside resistance. [YejG] (Mus musculus) PubMed

 25282.

The results presented here strongly suggest that GYP-3 is not part of the polarisome; however it requires the scaffold protein SPA-2 for arriving at the tip of hyphae [GYP-3]. (Mus musculus) PubMed

 25283.

SatS is required for the export of a subset of SecA2 substrates and for growth in macrophages and is a protein export chaperone [SatS] (Mus musculus) PubMed

 25284.

Adaptation to the host-attached state involves dynamic remodeling of enteropathogenic Escherichia coli gene expression, which is mediated by the relative levels of Tir and CesT [Tir]. (Mus musculus) PubMed

 25285.

Here, we report the presence of a sigma factor (SigN or ZpdN) that is encoded on a plasmid that leads to cellular death after DNA damage [ZpdN or SigN]. (Mus musculus) PubMed

 25286.

BcAP3 could play an essential role in stamen development and male sterility.[BcAP3] (Mus musculus) PubMed

 25287.

Findings identify the contributions of mutations of E560K/D/G in the highly conserved gp41 and highlight Env's high degree of plasticity for virus entry and inhibitor design [gp41]. (Mus musculus) PubMed

 25288.

RecQ is an ATP independent G4 DNA helicase that plays an important role in the regulation of G4 DNA structure dynamics and its impact on radioresistance in D. radiodurans. [RecQ] (Mus musculus) PubMed

 25289.

irena1 contributes to RNA interference and mitochondrial aggregation in mouse oocytes. Sirena1 exemplifies how lncRNAs stochastically engage or even repurpose molecular mechanisms during evolution. Simultaneously, Sirena1 expression levels and unique functional features contrast with the lack of functional importance assessed under laboratory conditions (Mus musculus) PubMed

 25290.

circ_0000285 promoted podocyte injury via sponging miR-654-3p and activating MAPK6 in diabetic nephropathy. [Circ_0000285] (Mus musculus) PubMed

 25291.

Our results show for the first time an active nuclear transport process of the EhAgo2-2 RNA-induced silencing complex (RISC) in this parasite [Ago2-2]. (Mus musculus) PubMed

 25292.

Our results show that intravacuolar-network-associated GRAs, particularly GRA2 and GRA12, play dynamic and essential roles in the development and maturation of the cyst matrix and the cyst wall structures [GRA1; GRA2]. (Mus musculus) PubMed

 25293.

Replication fidelity in E. coli: Differential leading and lagging strand effects for dnaE antimutator alleles [dnaE] (Mus musculus) PubMed

 25294.

Here, a novel bla IMP-68 gene encoding IMP-68 (harboring a Ser262Gly point mutant of IMP-11) was discovered from meropenem-resistant but imipenem-susceptible Klebsiella pneumoniae TA6363 [IMP-68]. (Mus musculus) PubMed

 25295.

expression of hdaB during stationary phase prepares cells to restart the replication of their chromosome as soon as conditions improve.[HdaB] (Mus musculus) PubMed

 25296.

RecBCD- RecFOR-independent pathway of homologous recombination in Escherichia coli [RecBCD][RecFOR] (Mus musculus) PubMed

 25297.

Results suggest that in N. crassa agmatinase-like protein-1 (AGM-1) has a close association with the F-actin population via its substrate agmatine, playing an essential role during cell development [AGM-1]. (Mus musculus) PubMed

 25298.

Several punctual mutations and a large-segment deletion among different strains were observed suggesting the involvement of triazole resistance mechanisms other than cyp51A [cyp51A]. (Mus musculus) PubMed

 25299.

BpuR bound to sodA mRNA in live B. burgdorferi, and a specific BpuR-binding site was mapped 5' of the sodA open reading frame. [BpuR] (Mus musculus) PubMed

 25300.

the DNA binding modes of Rap1 influence its functional properties, thus highlighting the structural plasticity of this protein.[Rap1] (Mus musculus) PubMed

 25301.

Mutation of the HTLV-1 vCTCF-BS does not significantly alter T-lymphocyte transformation capacity or early in vivo virus persistence, but results in a decreased HTLV-1-specific antibody response during early infection in rabbits [CTCF]. (Mus musculus) PubMed

 25302.

iron availability determines the basal amount of ZafA that is synthesized under zinc-replete conditions by an unprecedented mechanism that involves the iron-dependent expression of different transcription subunits of zafA (zafA) (Mus musculus) PubMed

 25303.

Phloretin hydrolase structure and amino acids which are essential for the activity towards phloretin.[phloretin hydrolase ] (Mus musculus) PubMed

 25304.

The role of F1 FO ATP synthase gamma-loop in the sodium translocation and ATP synthesis.[F1 FO ATP synthase] (Mus musculus) PubMed

 25305.

Evaluation of hypersusceptible mutants identified the association between lptG and a hypersusceptible phenotype. Modifications in lipopolysaccharide profiles suggests LptG modification interferes with lipopolysaccharide transport and contributes to hypersusceptibility.[LptG] (Mus musculus) PubMed

 25306.

Results showed that tubulins Tub1 and Tub2 share similar subcellular localization and have overlapping functions during vegetative growth but they differ in functions in DON production and ascosporogenesis in F. graminearum [Tub1; Tub2]. (Mus musculus) PubMed

 25307.

results demonstrate that ASL18a and NF-Y together regulate nodule organogenesis; thus, a lateral root developmental pathway is incorporated downstream of NIN to drive nodule symbiosis [ALS18a] (Mus musculus) PubMed

 25308.

Binding to FnIII repeats was mediated through conserved structural determinants present within the Scl1 globular domain and facilitated Streptococcus pyogenes adherence and biofilm formation.[Scl1] (Mus musculus) PubMed

 25309.

HaOr7 gene that confers resistance to Orobanche cumana race F-which was found to encode a leucine-rich repeat receptor-like kinase. [HaOr7] (Mus musculus) PubMed

 25310.

SET3 exhibits genetic activation of NAB3 that is observed in a sensitized context.[Nab3, SET1, SET3] (Mus musculus) PubMed

 25311.

the processing of RNase P-dependent polycistronic tRNA operons to release pre-tRNAs is the essential function of the enzyme.[Rnase P] (Mus musculus) PubMed

 25312.

the Mtf1 C-tail promotes RNA growth during initiation by stabilizing the scrunched DNA conformation.[Mtf1] (Mus musculus) PubMed

 25313.

A positive feedback loop between H2O2 accumulation and CaWRKY41 up-regulation coordinates the responses of pepper to R. solanacearum inoculation and Cd exposure. [CaWRKY41] (Mus musculus) PubMed

 25314.

the dual benefits of Nup62 and nsp1beta binding for PRRSV replication: the inhibition of host antiviral protein expression and the exclusive use of host translation machinery by the virus. Our study unveils a novel strategy of PRRSV for immune evasion and enhanced replication during infection. (Mus musculus) PubMed

 25315.

Divalent-selective channel in the metal ion transport superfamily CorA (CorA ) conformational changes and dynamics upon Mg2+-depletion: [CorA] (Mus musculus) PubMed

 25316.

5-fluorouracil can form a stable complex with Pseudomonas aeruginosa DHPase.[DHPase] (Mus musculus) PubMed

 25317.

the active site of YhfI is located at a metal-containing pocket generated between the two subunits of a YhfI dimer.[YhfI] (Mus musculus) PubMed

 25318.

The lack of metallothionein Mt1 did not alter the pathogenic capacity of the fungus, either in tomato plant or in a murine model of systemic infection. Nevertheless, Deltamt1 displayed lower resistance to macrophage killing, suggesting a connection between the absence of mt1 and impaired defence capacity against copper and reactive oxygen species. [Mt1] (Mus musculus) PubMed

 25319.

The genic expression of LvUCP4 and LvUCP5 was evaluated in shrimp at oxidative stress conditions and results were compared to some antioxidant enzymes to infer about their antioxidant role. LvUCP4 and LvUCP5 genes expression did not change during hypoxia/re-oxygenation, and no coordinated responses were detected with antioxidant enzymes at the transcriptional level. (Mus musculus) PubMed

 25320.

Identification of mutations at FOXP3 binding site within BIC gene that result in increased expression of miR-155 in pig (BIC). (Mus musculus) PubMed

 25321.

In Japanese flounder, sqt as a target of miR-430a was enriched into heart development term. Overexpression and suppression of miR-430a resulted in abnormal KV (Kupffer's vesicles) development and disordered in nodal-related expression with consequent cardiac laterality. These results suggested that miR-430a regulates the development of left-right asymmetry by targeting sqt in the teleost.[mir430a] (Mus musculus) PubMed

 25322.

The restraining effect of miR-545-3p on osteogenesis is mediated via LRP5/Wnt/beta-catenin signaling. miR-545-3p is transcriptionally activated by SP1. [miR-545-3p] (Mus musculus) PubMed

 25323.

NONHSAG053901 promoted proinflammatory cytokines via stimulating Egr-1/TGF-beta mediated renal inflammation.[NONHSAG053901] (Mus musculus) PubMed

 25324.

AUF1 knockdown resulted in upregulation of GKN1 expression and promoted GKN1 mRNA decay by binding the 3' untranslated region of GKN1 mRNA H. pylori-induced AUF1 expression was associated with p-ERK activation and CagA. (Mus musculus) PubMed

 25325.

This study found that an 8 residue motif in polycystin 1 is sufficient to bind protein phosphatase 1 (PP1alpha), a ubiquitously expressed phosphatase in the phosphoprotein phosphatase family.[PP1alpha] (Mus musculus) PubMed

 25326.

Expression of nitric oxide synthase (NOS) in Anabas testudineus ovary and participation of nitric oxide-cyclic GMP cascade in maintenance of meiotic arrest. (Mus musculus) PubMed

 25327.

results indicate that Hfq2 is not a pseudogene but plays important roles on the essential physiological functions in A. hydrophila. (Mus musculus) PubMed

 25328.

This study characterized Am2136 as a beta-N-acetylhexosaminidase from Akkermansia muciniphila to perform the biochemical characteristics and the crystal structure of selenomethionine-labeled Am2136 with GlcNAc complex. Crystallographic evidence suggests that an oxazolinium ion was formed intermediately by the 2-acetamido group during the substrate-assisted catalytic procedure. [Am2136] (Mus musculus) PubMed

 25329.

StyR interacts with the styAB promoter by binding to the palindrome in the styAB promoter.[styAB] (Mus musculus) PubMed

 25330.

two crystal structures of C-terminal domain of eIF5 from Candida albicans, which for the first time showed the AA-box2 of eIF5 presenting as an ordered helical structure.[eIF5] (Mus musculus) PubMed

 25331.

rescue assays demonstrated the function of SP1-SYNE1-AS1 axis in Cardiac hypertrophy (CH). In conclusion, SP1-induced upregulation of lncRNA SYNE1-AS1 promoted CH via miR-525-5p/SP1 axis. (Mus musculus) PubMed

 25332.

Mutation profile of rdxA and frxA genes in a population of 38 H. pylori isolates with phenotypic patterns of susceptibility and resistance to this antibiotic. (Mus musculus) PubMed

 25333.

The functional complementation of the S. cerevisiae ZRT1Delta ZRT2Delta mutant with U. maydis genes supports this as well. U. maydis ZRT2 gene, was found to be regulated by pH through Rim101 pathway, thus providing novel insights into how this Basidiomycota fungus can adapt to different levels of Zn availability. (Mus musculus) PubMed

 25334.

Crystal structure and biochemical characterization of O-acetylhomoserine acetyltransferase from Mycobacterium smegmatis ATCC 19420 have been reported [O-acetylhomoserine acetyltransferase] (Mus musculus) PubMed

 25335.

the functions of Htt during growth and development of the protist, Dictyostelium discoideum, was investigated.[Htt] (Mus musculus) PubMed

 25336.

The specificity of Staphylococcus aureus Cas9 under a variety of experimental conditions was eveluated. (GENE: Cas9) (Mus musculus) PubMed

 25337.

This study identified a cluster of three basic residues (Lys48, His259 and Arg262) in AhSIP distributed around a potential substrate binding pocket.[AhSIP] (Mus musculus) PubMed

 25338.

we identified DNA recombination during the oocyte meiotic prophase I and lysine trimethylation of the histone H3K27 during the oocyte growth phase as molecular pathways modulated by ActA. (Mus musculus) PubMed

 25339.

OsACS1 and 2 are required for Pi acquisition to maintain Pi homeostasis via the induction of known Pi starvation-induced genes. [ACS1, ACS2] (Mus musculus) PubMed

 25340.

the KSHV-encoded miRNA miR-K4-5p, and probably miR-K1-5p, directly targeted CASTOR1 to inhibit its expression. Knockdown of miR-K1-5p and -K4-5p restored CASTOR1 expression and thereby attenuated mTORC1 activation. (Mus musculus) PubMed

 25341.

Yvc1 governed polarized growth through regulating reactive oxygen species gradient (Yvc1) (Mus musculus) PubMed

 25342.

CTXphi uptake requires TcpB-mediated retraction.[TcpB] (Mus musculus) PubMed

 25343.

LpqN may act as a membrane fusion protein, connecting MmpL transporters with periplasmic proteins, and provide general insight into the role of lipoproteins in Mycobacterium tuberculosis cell envelope biogenesis.[LpqN] (Mus musculus) PubMed

 25344.

Here, we reported dimeric structures of the tyrosine-regulated DAHPS from Escherichia coli, both in its apo form and complex with the inhibitor tyrosine at 2.5 and 2.0A resolutions, respectively. (Mus musculus) PubMed

 25345.

Study identified a single mutation, S64V, which significantly reduced the rate of alternating access but did not impair substrate binding. Six other transport-impaired mutants did not have reduced alternating access rates, highlighting the importance of other aspects of the transport cycle to achieve drug resistance activity. [EmrE] (Mus musculus) PubMed

 25346.

HD-Pnk is a copper-dependent p-nitrophenylphosphatase.[HD-Pnk] (Mus musculus) PubMed

 25347.

The enzymatic properties and physiological functions of two secretory phospholipases A1 (PLA1s), PLA1-1 and PLA1-2, while PLA1-1 displayed PLA1 activity to phosphatidylcholine and phosphatidylethanolamine, and PLA1-2 exhibited PLA1 activity only to phosphatidylglycerol: [PLA1-1 and PLA1-2] (Mus musculus) PubMed

 25348.

Overexpression of host miR-89 significantly suppressed the replication of a variety of porcine reproductive and respiratory syndrome virus.[miR-89] (Mus musculus) PubMed

 25349.

LPMO depolymerized of cellulose reactions are driven by light. [LPMO] (Mus musculus) PubMed

 25350.

NdhV assists in the binding of Fd to NDH-1 and accelerates cyclic-electron-transfer around photosystem I in response to short-term high-light exposure.[NDH-1] (Mus musculus) PubMed

 25351.

UbaC has an important function in Ubl ligation and is associated with sulfur relay processes. [UbaC] (Mus musculus) PubMed

 25352.

CobW1, CobW2, and CobW3 are essential components to metal homeostasis.[CobW1, CobW2, and CobW3] (Mus musculus) PubMed

 25353.

SrrAB regulates a ClpC and ClpP complex to facilitate energy homeostasis in S. aureus.[ClpC,ClpP, SrrAB] (Mus musculus) PubMed

 25354.

This study highlights the effect of heavy metal ions on the expression of cobalt-containing nitrile hydratase (NHase) in Rhodococcus rhodochrous, which over-produce this enzyme. Nickel ions can derepress the NHase promoter. [nitrile hydratase] (Mus musculus) PubMed

 25355.

Study presents genetic and biochemical evidence that the yiiD (renamed fabY)-encoded function contributes to the biosynthesis of fatty acid in the absence of FabH activity and that under these conditions, the expression of FabY was regulated by the stringent response factors (p)ppGpp and DksA. Combined inactivation of FabH and FabY resulted in growth arrest, possibly due to the loss of fatty acid biosynthesis. [FabY] (Mus musculus) PubMed

 25356.

Tm0107 forms a homodimer in a manner different compared to other structurally characterized diguanlyate cyclase proteins.[Tm0107] (Mus musculus) PubMed

 25357.

These data suggest that kinesin-5 (Kip1)-independent mechanisms drive assembly and elongation of the mitotic spindle in Candida albicans and that CaKip1 is important for bipolar spindle integrity. They also found that simultaneous loss of kinesin-5 and kinesin-14 (CaKar3CaKip1) activity is lethal.[Kip1, Kar3] (Mus musculus) PubMed

 25358.

Although the LeishIF4E1(-/-) null mutant was viable, its growth was impaired, in line with a reduction in global translation. As a result of the mutation, the null LeishIF4E1(-/-) mutant had a defective morphology, as the cells were round and unable to grow a normal flagellum.[eIF4E1] (Mus musculus) PubMed

 25359.

Studies indicate that rapeseed (Brassica napus L.) calcium-dependent protein kinase (BnaCPK6L) plays an important role in reactive oxygen species (ROS) and HR-like cell death through interacting with and phosphorylating BnaRBOHD (Respiratory Burst Oxidase Homolog D): [CPK6L and RBOHD] (Mus musculus) PubMed

 25360.

Both psaE and psaF are required for psaA transcription in Y. pestis and that the impact of temperature and pH is mediated through discrete posttranscriptional effects on PsaE and PsaF.[psaE] (Mus musculus) PubMed

 25361.

These studies evaluated the expression of curli and the cytotoxic properties of its amyloid intermediates.[curli] (Mus musculus) PubMed

 25362.

PhoP specifically binds the hilA promoter to block binding of activators HilD, HilC, and RtsA as a mechanism of repression. [PhoP] (Mus musculus) PubMed

 25363.

In Escherichia coli, the dimeric AraC protein actively represses transcription from the l-arabinose araBAD operon in the absence of arabinose but induces transcription in its presence. This study provides evidence that, in shifting from the repressing to the inducing state, the behavior of the interdomain linker shifts from that of an alpha helix to that of a more flexible form. [AraC] (Mus musculus) PubMed

 25364.

Comparison of the hydrogen-deuterium exchange kinetics of individual dimeric dimerization domains and the full-length dimeric AraC protein in the presence and absence of arabinose reveals a prominent arabinose-induced destabilization of the amide hydrogen-bonded structure of linker residues (I167 and N168). [AraC] (Mus musculus) PubMed

 25365.

Malonyl-CoA (MCoA), methylmalonyl-CoA (MMCoA), and ethylmalonyl-CoA (EMCoA) are used as extension units in salinomycin biosynthesis. To understand how the salinomycin modular polyketide synthase (PKS) strictly discriminates among these extension units, the acyltransferase (AT) domains selecting MCoA, MMCoA, and EMCoA were structurally characterized. [Salinomycin Polyketide Synthase] (Mus musculus) PubMed

 25366.

CAMK2G was knocked down in primary kidney cells. CAMK2G knockdown impaired ouabain-dependent protection from apoptosis upon treatment with high glucose or serum deprivation. CAMK2G is a downstream effector of NKA which is a receptor for the cardiotonic steroid ouabain. NKA. CAMK2G. (Mus musculus) PubMed

 25367.

Melatonin restores Muc2 depletion induced by V. vulnificus VvpM via melatonin receptor 2 coupling with Galphaq. (Mus musculus) PubMed

 25368.

Results show that the RAG1 glucose permease gene is synergistically induced by hypoxia and glucose and highlighted a novel role for the transcriptional activator Sck1 as a key mediator in this mechanism [RAG1]. (Mus musculus) PubMed

 25369.

Altogether these results point out to StNAC101 as a candidate to repress the suberin-associated waxes.[NAC101] (Mus musculus) PubMed

 25370.

The expression of MdERF11 is significantly induced in apple fruits after Botryosphaeria dothidea infection. Overexpression of MdERF11 gene in apple calli significantly increases the resistance to B. dothidea infection, while silencing MdERF11 in apple calli results in reduced resistance. (Mus musculus) PubMed

 25371.

These results suggested that CaNAC064 positively modulates plant cold-tolerance, laying the foundation for future investigations into the role of NACs as regulatory proteins of cold tolerance in plants. [NAC064] (Mus musculus) PubMed

 25372.

cryo-electron microscopy to identify the molecular gating mechanism in calcium-activated potassium channels by obtaining structures of the MthK channel from Methanobacterium thermoautotrophicum-a purely calcium-gated and inactivating channel-in a lipid environment [MthK] (Mus musculus) PubMed

 25373.

crystal structure of HPF1 from Nematostella vectensis [HPF1] (Mus musculus) PubMed

 25374.

RON2 is a novel antigen in B. bigemina and contains conserved B-cell epitopes, which induce antibodies that inhibit merozoite invasion [RON2]. (Mus musculus) PubMed

 25375.

SseK2 is a virulence-associated gene that plays a vital role in Salmonella virulence. [sseK2] (Mus musculus) PubMed

 25376.

We describe a new regulatory mechanism, where an unreported lncRNA, PTPRE-AS1, targets receptor-type tyrosine protein phosphatase epsilon (PTPRE) to regulate macrophage activation. (Mus musculus) PubMed

 25377.

Data report the high-resolution cryo-EM structure of the copolymeric filaments of Pseudomonas aeruginosa MinCD. The filaments consist of three protofilaments made of alternating MinC and MinD dimers. The MinCD protofilaments are almost completely straight and assemble as single protofilaments on lipid membranes. [MinC; MinD] (Mus musculus) PubMed

 25378.

The VicRK two-component system regulates Streptococcus mutans virulence. [VicR] (Review) (Mus musculus) PubMed

 25379.

Structure and function of ComDE two-component signal transduction systems in oral Streptococci have been summarized. [ComD], [ComE] (Review) (Mus musculus) PubMed

 25380.

L protein was in complex with a 91-residue, N-terminal fragment of P (P1-91) shown by electron cryo-microscopy. [p protein] (Mus musculus) PubMed

 25381.

HDX-MS shows that the presence of acyl chains in CyaA induces a significant stabilization of the apolar segments of the hydrophobic domain and of most of the acylation region. Refolding may be dependent on calcium and driven by local and distal acylation-dependent interactions within CyaA. CyaA acylation is not only critical for cell intoxication, but also for protein refolding into its active conformation. CyaA. (Mus musculus) PubMed

 25382.

Structural and functional connections between the active site and the allosteric site were indicated by equilibrium binding experiments, which revealed different pyridoxal 5'-phosphate -binding stoichiometries with WT and mutant PNPOx forms.[PNPox] (Mus musculus) PubMed

 25383.

The peptide domains of 3b involved in nucleolar localization. [3b] (Mus musculus) PubMed

 25384.

This study supports the hypothesis that the OsDHSRP1 E3 ligase acts as a negative regulator, and the degradation of its substrate proteins via ubiquitination plays important roles in regulating various abiotic stress responses via an abscisic-independent pathway. (Mus musculus) PubMed

 25385.

Data report that noncoding RNA NfiS regulates optimal oxidative stress resistance via direct binding with katB mRNA. [NfiS, katB] (Mus musculus) PubMed

 25386.

The gliding motility adhesin SprB is delivered to the cell surface by the type IX secretion system and is rapidly propelled along the cell by the motility machinery. Fusion of its C-terminal 218 amino acids to a foreign cargo protein resulted in its secretion, attachment to the cell surface, and rapid movement. Efficient secretion of SprB required coexpression with the outer membrane protein SprF. [SprB, SprF] (Mus musculus) PubMed

 25387.

Sequence analyses attribute the haloarchaeal pentose ABC transporter to the CUT1 (carbohydrate uptake transporter 1) subfamily [CUT1]. (Mus musculus) PubMed

 25388.

silencing OsMAPK20-5 has different effects on rice pests in the field.[OsMAPK20-5] (Mus musculus) PubMed

 25389.

TAB1 seems not to be involved in meristem maintenance, irrespective of the meristem type.[TAB1] (Mus musculus) PubMed

 25390.

Deletion of autophagy-related protein Atg11 led to the defect in growth under the nitrogen starvation condition. [Atg11] (Mus musculus) PubMed

 25391.

The authors found that stable expression of a Human T-cell leukemia virus type 1 (HTLV-1) accessory protein, HTLV-1 bZIP factor (HBZ), in Jurkat T cells increases homotypic aggregation. This phenotype was attributed to elevated ICAM-1 expression in the presence of HBZ.[HBZ] (Mus musculus) PubMed

 25392.

The dodecamer structure of TmPep1050 also reveals that a part of the dimerization domain delimits the catalytic pocket and could participate in substrate binding.[TmPep1050] (Mus musculus) PubMed

 25393.

PbS10 mutants suffered growth attenuation at an early stage while PbS23/SSP3 mutants manifested defect during late exo-erythrocytic form maturation. [PbS10, PbS23] (Mus musculus) PubMed

 25394.

SIVgsn71 Vpu requires two AxxxxxxxW (A(22)W(30) and A(25)W(33)) motifs to antagonize human BST-2, suggesting an as-yet-undefined way that SIVgsn71 Vpu works against human BST-2. These results imply an evolutionary impact of primate BST-2 on lentiviral Vpu. (Mus musculus) PubMed

 25395.

Results show that the transcription of class II pilE is maintained throughout growth and under different stress conditions and is driven by a sigma(70)-dependent promoter. [class II pilE] (Mus musculus) PubMed

 25396.

the crystal structure of Thermotoga maritima TmAgu4B, a GH4 alpha-glucuronidase, in complex with Co(2+) and citrate, is reported.[TmAgu4B] (Mus musculus) PubMed

 25397.

This study determined the crystal structures of Klebsiella pneumoniae 5-(Hydroxyethyl)-methylthiazole kinase (ThiM) and in complex with the natural substrate 5-(hydroxyethyl)-4-methylthiazole, both at 2.0A resolutions. [5-(Hydroxyethyl)-methylthiazole kinase] (Mus musculus) PubMed

 25398.

This study used X-ray crystallography to describe the structure of an short-chain dehydrogenase/reductase (SDR) from the multi-drug resistant bacteria A. baumannii, previously annotated as a putative FASII FabG enzyme. [short-chain dehydrogenase/reductase] (Mus musculus) PubMed

 25399.

TsdAs from Campylobacter jejuni, a microaerobic human pathogen, and from the purple sulfur bacterium Allochromatium vinosum, were examined.[TsdA] (Mus musculus) PubMed

 25400.

TsdAs from Campylobacter jejuni, a microaerobic human pathogen, and from the purple sulfur bacterium Allochromatium vinosum, were examined.[TsdA] (Mus musculus) PubMed

 25401.

Escherichia coli RcnR was crystallized with DNA that encompasses the DNA-binding site. X-ray diffraction data were collected to 2.9 A resolution. (Mus musculus) PubMed

 25402.

These data revealed that TprA expression is modulated by a complex regulatory network, where the master regulators CcpA and GlnR are involved in a sugar dependent manner. Mutants in the TprA/PhrA system are highly attenuated in their survival in nasopharynx and lungs after intranasal infection, and growth in blood after intravenous infection.[GlnR, TprA, PhrA] (Mus musculus) PubMed

 25403.

These results suggest that the ME49Deltagra17 strain is avirulent and is cleared before it can reach the brain and that GRA17 not only plays an important role during acute infections but is also needed for viability of bradyzoites inside cysts.[GRA17] (Mus musculus) PubMed

 25404.

an immunosuppressive strategy of S. suis whereby the bacterium blunts the innate host defenses via ApdS protease-mediated LL-37 cleavage.[ApdS] (Mus musculus) PubMed

 25405.

The authors showed that TAK1, MAP kinase kinase 4 (MKK4), and JNK were activated in 293T cells transfected with the NS1 gene of the H5N1 virus. (Mus musculus) PubMed

 25406.

MazF is a sequence-specific endoribonuclease or mRNA interferase, which cleaves RNA at a specific sequence. This study identified a gene for a MazF homologue (MazFme) from Methanohalobium evestigatum, an extremely halophilic archaeon. [MazF homologue] (Mus musculus) PubMed

 25407.

The authors found that simultaneously expressing the full-length PA-X and PB1-F2 proteins enhanced viral replication in vitro through increasing the accumulation of the RNP complex protein and enhanced viral pathogenicity in mice during the early stage of infection.[PA-X, PB1-F2] (Mus musculus) PubMed

 25408.

AK005401/YY1/FGF21 signaling pathway has an important role in I/R-mediated hippocampal injury [LncRNA AK005401] (Mus musculus) PubMed

 25409.

Results identified a specific desuccinylase ScCobB2 and provide evidence that the enzymes related to protein biosynthesis and carbon metabolism in S. coelicolor were extensively modified by succinylation and highly regulated by the desuccinylase ScCobB2. [CobB2] (Mus musculus) PubMed

 25410.

The ribosome-binding mutant inhibited the unfolded protein response without affecting IRE1 oligomerization or cleavage of HAC1(u) mRNA at the splice site junctions.[HAC1] (Mus musculus) PubMed

 25411.

Kinetic cooperativity is an inherent property of non-regulated family II pyrophosphatases. Cooperativity of family II pyrophosphatase is modulated by magnesium ion binding. [family II pyrophosphatase] (Mus musculus) PubMed

 25412.

Study report the crystal structure of DppA from H. pylori. Based on the analysis of the electron density maps, the protein was confirmed to co-purify with peptides. In deed, HpDppA binds peptides of diverse amino acid sequences with micromolar affinity. [DppA] (Mus musculus) PubMed

 25413.

Data show that in X. citri, ecnA is involved in important processes, such as biofilm formation, exopolysaccharide (EPS) production, and motility. In addition, ecnA plays a role in X. citri survival and virulence in host plants. Thus, this mechanism represents an important bacterial strategy for survival under stress conditions. [ecnA] (Mus musculus) PubMed

 25414.

In response to bound autoinducing peptide (AIP), the cytoplasmic domain of AgrC (AgrC-cyt) undergoes conformational changes resulting in dimerization, autophosphorylation, and phosphotransfer to AgrA. Natural aa substitution in AgrC-cyt are consistent with repositioning of key functional domains leading to reduced AIP autoinduction. These may have implication in the adaptation of S. aureus during infection. [AgrC] (Mus musculus) PubMed

 25415.

Results showed that H. pylori HP0416 gene encodes a functional cyclopropane fatty acids synthase (CfaS). The enzyme was demonstrated to be required for acid resistance, antibiotic resistance, intracellular survival and mouse gastric colonization, and cell membrane integrity. [CfaS] (Mus musculus) PubMed

 25416.

The first glycoprotein core xylosidase that can remove core xylose directly from glycoprotein (gpcXase I) was reported. In E. meningoseptica, the gpcXase I and core fucosidase cFase I formed a functional operon for core oligosaccharide modifications. [gpcXase I] (Mus musculus) PubMed

 25417.

Crystal structure of geranylgeranyl pyrophosphate synthase (GGPPS) from Nonlabens dokdonensis DSW-6 was determined. GGPPS structure is composed 15 alpha-helices and shows a class I terpenoid synthase fold. GGPPS might function as a short-chain prenyltransferase. [geranylgeranyl pyrophosphate synthase] (Mus musculus) PubMed

 25418.

The ESCRT-0 protein HRS interacts with the HTLV-II antisense protein APH-2 and suppresses viral replication. [APH-2] (Mus musculus) PubMed

 25419.

In this paper, we determine crystal structures of Pro-Esp and its variants to localize the pro-peptide in relation to the main body of the enzyme and to understand the structure-function relationships of such an extended N-terminus and specifically the residues responsible for Pro-Esp inactivity and activation. (Mus musculus) PubMed

 25420.

KirBac1.1 changes the phase properties and dynamics of the surrounding bilayer [KirBac1.1] (Mus musculus) PubMed

 25421.

dynamin GTPase Dnm1 is required for promoting mitochondrial fragmentation.[Dnm1] (Mus musculus) PubMed

 25422.

the opine dehydrogenase reaction would be reversible only for the opine metallophore product with (R)-stereochemistry at carbon C2 of the alpha-keto acid (prochiral prior to catalysis).[ODH] (Mus musculus) PubMed

 25423.

the opine dehydrogenase reaction would be reversible only for the opine metallophore product with (R)-stereochemistry at carbon C2 of the alpha-keto acid (prochiral prior to catalysis).[ODH] (Mus musculus) PubMed

 25424.

A novel bacterial glycoside hydrolase 64 with Ca(2+)-dependent activity modulation has been characterized and termed glucanallin. [Glucanallin] (Mus musculus) PubMed

 25425.

Data show that Desulfovibrio vulgaris Hcp has nitric oxide reductase activity with benzyl viologen as electron donor. With EPR spectroscopy, three unexpected putative reaction intermediates were identified: both in reduced and oxidized Hcp, dinitrosyl iron complexes are formed. Also, the hybrid cluster in reduced Hcp, but not in oxidized Hcp, binds the product N2 O. [hcp] (Mus musculus) PubMed

 25426.

O. tauri adjusts its copper economy in response to copper deficiency by downregulation of the expression of plastocyanin and increased expression of copper transporting ATPase. This study identified Fea1 as the major iron binding protein in O. tauri, supporting the role of algal phytotransferrin-like proteins in iron acquisition. [plastocyanin, copper-transporting ATPase, Fea1] (Mus musculus) PubMed

 25427.

Tp47 promotes the migration and adherence of THP-1cells to human dermal vascular smooth muscle cells by inducing MCP-1 and ICAM-1 expression (Tp47) (Mus musculus) PubMed

 25428.

the crystal structure of Corynebacterium glutamicum GABA aminotransferase in complex with pyrodoxal phosphate-GABA, is reported.[GABA-AT] (Mus musculus) PubMed

 25429.

Using a fluorescence polarization 30S-binding assay and a new crystal structure of the methyltransferase RmtC at 3.14 A resolution, this study reports a structure-guided functional study of 30S substrate recognition by the aminoglycoside resistance-associated 16S rRNA (m(7)G1405) methyltransferases. [RmtC] (Mus musculus) PubMed

 25430.

3-Mercaptopropionic Acid Dioxygenase S-H-Y Motif Gates Substrate-Coordination Denticity at the Non-Heme Iron Active Site [MDO] (Mus musculus) PubMed

 25431.

the structures of NdmA and NdmB, the initial N1- and N3-specific demethylases, respectively, are reported.[NdmA, NdmB] (Mus musculus) PubMed

 25432.

The authors have identified two novel Streptococcus pyogenes superantigens, denoted speQ and speR, adjacent to each other in the core-chromosome of isolates belonging to eleven different emm-types.[speQ, speR] (Mus musculus) PubMed

 25433.

The Vif of caprine arthritis encephalitis virus negatively regulates host IFN-beta production by affecting upstream signal transduction of IRF3.[Vif] (Mus musculus) PubMed

 25434.

The Vif of caprine arthritis encephalitis virus negatively regulates host IFN-beta production by affecting upstream signal transduction of IRF3.[IFN-beta] (Mus musculus) PubMed

 25435.

This article has compiled the literature reports highlighting the effect of mutations and N-terminal deletion of residues of SARS-CoV main protease (M(pro)) or 3-chymotrypsin-like cysteine protease on its dimerization and, thus, catalytic activity. [main protease] (Mus musculus) PubMed

 25436.

CsCAF1 with canker development and PthA4-dependent transcription in citrus plants.[CsCAF1] (Mus musculus) PubMed

 25437.

va resistance durability can in large part be explained by complex redundancy effects in the eIF4E gene family.[Va, eif4e] (Mus musculus) PubMed

 25438.

Aminodeoxychorismate synthase consists of the synthase subunit PabB and the glutaminase subunit PabA, which is allosterically stimulated by the presence of the PabB substrate chorismate. Steady-state kinetic characterization revealed four branches of a conserved network of mainly charged residues that propagate the signal from chorismate at the PabB active site to the PabA active site. [PabA, PabB] (Mus musculus) PubMed

 25439.

cdsA is induced through two-step cold-induction to maintain MPIase at a high level rapidly and sustainably in the cold [cdsA][MPIase] (Mus musculus) PubMed

 25440.

Cytochrome bo3 has been shown recently to also utilize demethylmenaquinol-8 as a substrate that, along with menaquinol-8, replaces ubiquinol-8 when E. coli is grown under microaerobic or anaerobic conditions. This work shows that its steady-state turnover with 2,3-dimethyl-1,4-naphthoquinol, a water-soluble menaquinol analogue, is just as efficient as with ubiquinol-1. [Cytochrome bo3] (Mus musculus) PubMed

 25441.

molecular dynamics simulations were used to analyze the structural discrepancy between wild-type and Sgf73 H93A mutant.[Sgf73] (Mus musculus) PubMed

 25442.

In the regulation of DNA damage response and virulence in Candida albicans, Ptc2 shows a negative interaction with Pph3, but positive interaction with either Psy2 or Psy4 [Ptc2]. (Mus musculus) PubMed

 25443.

the 1.7-A x-ray crystal structure of kringle 2 (KR2) domain of host Plg in complex with a monomeric Plasminogen (Plg)-binding M protein peptide that contains both the a1 and a2 motifs, is reported.[M protein] (Mus musculus) PubMed

 25444.

a cis-element referred to as "nuclear zip code" in SKS1 mRNA, is reported.[SKS1] (Mus musculus) PubMed

 25445.

RsmY has its higher expression during the stationary growth phase, and in the absence of RsmZ1, rsmY increases its transcription. [rsmY] (Mus musculus) PubMed

 25446.

RRM1 facilitates the RNA Pol II transcriptional elongation step by collaborating to maintain an open chromatin state in particular regions of the genome. [RRM1] (Mus musculus) PubMed

 25447.

ScRas2 functionally complements CaRas1 in rescuing growth as well as activating hyphal growth.[ras2] (Mus musculus) PubMed

 25448.

the physiochemical profiling, modelling, and docking of the Rab5 protein from pathogenic species that is Entamoeba histolytica, Leishmania donovani, and Toxoplasma gondii, are reported.[Rab5] (Mus musculus) PubMed

 25449.

the findings describe the unrecognized regulatory role of Flp protein that controls hrp gene expression and pathogenesis in Xanthomonas campestris pv. campestris.[Flp] (Mus musculus) PubMed

 25450.

This study determined the crystal structure of maleylpyruvate isomerase from Pseudomonas aeruginosa PAO1 at a resolution of 1.8A. Pseudomonas aeruginosa PAO1 (PaMPI) at a resolution of 1.8A. PaMPI functions as a dimer and shows the glutathione S-transferase fold. [maleylpyruvate isomerase] (Mus musculus) PubMed

 25451.

MoHat1, a histone acetyltransferase (HAT) homolog, had a role in the regulation of autophagy through the acetylation of autophagy related proteins MoAtg3 and MoAtg9 (Hat1). (Mus musculus) PubMed

 25452.

Efflux pumps and ERG11 may be involved in resistance to azoles [ERG11]. (Mus musculus) PubMed

 25453.

The mosquito P47Rec(AGAP006398 )has two natterin-like domains and binds to Pfs47 with high affinity. [Pfs47] (Mus musculus) PubMed

 25454.

This study determined an X-ray crystal structure of the T7 DNA polymerase (gp5) bound to both a primer/template DNA and a peptide that mimics the C-terminal tail of the primase-helicase. [DNA polymerase (gp5)] (Mus musculus) PubMed

 25455.

distinct motifs crucial for endocytosis, transport activity, substrate specificity and folding, in both cytosolic termini of FurE, are reported.[FurE] (Mus musculus) PubMed

 25456.

Structural and Functional Characterization of YdjI [Ydji] (Mus musculus) PubMed

 25457.

These observations suggest that Ste20 and Cla4 not only have a role in the transcriptional regulation of GPD1 through Ste11.[Ste20, Cla4, Gpd1] (Mus musculus) PubMed

 25458.

OsMPK1 phosphorylates bip130 at Thr-153 to regulate abscissic acid-induced antioxidant defense.[bip130] (Mus musculus) PubMed

 25459.

the physiochemical profiling, modelling, and docking of the Rab5 protein from pathogenic species that is Entamoeba histolytica, Leishmania donovani, and Toxoplasma gondii, are reported.[Rab5] (Mus musculus) PubMed

 25460.

the physiochemical profiling, modelling, and docking of the Rab5 protein from pathogenic species that is Entamoeba histolytica, Leishmania donovani, and Toxoplasma gondii, are reported.[Rab5] (Mus musculus) PubMed

 25461.

Residues in the J-protein binding region of DnaK interact directly with the Hsp90 middle-domain. [DnaK, Hsp90] (Mus musculus) PubMed

 25462.

Zn binding dramatically reduces the Fe-S cluster assembly activity of Isu1 even in the presence of frataxin.[Isu1] (Mus musculus) PubMed

 25463.

Functional Characterization of YdjH in Escherichia coli K12 [YdjH] (Mus musculus) PubMed

 25464.

two yclopropane Mycolic Acid Synthase enzymes, proximal alpha cyclopropane mycolic acid synthase (PcaA/CmaA3) and keto cyclopropane Mycolic acid synthase (CmaA2), were studied.[CmaA3, CmaA2] (Mus musculus) PubMed

 25465.

Results find the prevalence of NS5A resistance-associated substitutions (RAS) in genotype (GT) GT1a HCV in Australia was low compared with international data, and was similar to other reported international prevalence for GT1b and GT3 infection. (Mus musculus) PubMed

 25466.

Deltawzc (Deltasll0923) and Deltawzb (Deltaslr0328) influenced both the amount and composition of the extracellular polymeric substances. [Wzc, wzb] (Mus musculus) PubMed

 25467.

The stilbene synthase gene VpSTS29/STS2 from Vitis pseudoreticulata functions in the regulation of plant responses to powdery mildew. ( stilbene synthase VpSTS29/STS2 ) (Mus musculus) PubMed

 25468.

The authors described the effects of one of the genes found in the mutagenesis screen, encoding a putative enoyl-CoA hydratase (echA), on biofilm structure and tolerance to antimicrobials.[echA] (Mus musculus) PubMed

 25469.

ZmACD6 knockout maize plants, which are more susceptible to U. maydis than wild-type plants, were identified.[ZmACD6] (Mus musculus) PubMed

 25470.

High light and high temperature treatment influenced the expression of many genes in the ls1 mutant, while affecting the growth and development of young leaves.[ls1] (Mus musculus) PubMed

 25471.

(gene OXA-143) D224A and P227S act as deleterious and positive mutations, respectively, within the evolutionary path of the OXA-143 subfamily toward a more efficient carbapenemase. (Mus musculus) PubMed

 25472.

Transport property assays showed that LutP was essential for lactate uptake. Its regulator LutR directly interacted with the lutP-lutR intergenic region, and lutP transcription was activated by l-lactate via regulation by LutR. [lutP,lutR] (Mus musculus) PubMed

 25473.

This study provides evidence that RecFOR is dispensable for RecA to protect incoming exogenous DNA and to catalyze recombination during transformation. [RecFOR, RecA] (Mus musculus) PubMed

 25474.

OsFD1 binds to the promoters of and activates the expression of JAZ genes; Hd3a, cooperating with GF14e, promotes OsFD1 action on JAZ gene expression.[hd3a, OsFD1] (Mus musculus) PubMed

 25475.

Multiple proteins that show abundance changes after 1 and 5 min of heat shock (HS) -treatment are identified. Of the early HS-regulated proteins identified, the abundance of a ubiquitin-specific protease, UBP21, and its Arabidopsis homolog, AtUBP13, is found to be upregulated by 5 min of HS treatment. [UBP21] (Mus musculus) PubMed

 25476.

Regardless of the stressing conditions and the tested strains, the cshA promoter was active very early, while the biomass increased and always did so before the first cell division. In the ATCC 14579 strain, the onset of abrB promoter activity always started at between 30 min and 3 h, before biomass increased and cell division occurred. [cshA] (Mus musculus) PubMed

 25477.

Regardless of the stressing conditions and the tested strains, the cshA promoter was active very early, while the biomass increased and always did so before the first cell division. In the ATCC 14579 strain, the onset of abrB promoter activity always started at between 30 min and 3 h, before biomass increased and cell division occurred. [cshA] (Mus musculus) PubMed

 25478.

The results of colony PCRs and sequencing revealed that Com1 and OmpH were correctly cloned in pET-22b(+) vector. Finally, the results of expression, purification, and western blotting of both proteins showed thatBL21 (DE3) strain of Escherichia coli could be able to express Com1 and OmpH proteins. [Com1,OmpH] (Mus musculus) PubMed

 25479.

MOTS-c peptide prevents ovariectomy (OVX)-induced body weight gain and insulin resistance. [peptide] (Mus musculus) PubMed

 25480.

These findings suggest that NR3 is an active quinone reductase with a mode of action similar to NR1, but different from NR2. The biological function of this family of enzymes may reside in the use of xenobiotics as final electron acceptors.[NR3] (Mus musculus) PubMed

 25481.

(gene: lanthionine synthase) Structural and kinetic analysis of biosynthesis of H(2)S and l-Lanthionine from l-Cysteine by lanthionine synthase was performed. (Mus musculus) PubMed

 25482.

ZmWRKY114 may function as a negative factor that participates in salt-stress responses through an abscisic acid -mediated pathway. (WRKY114) (Mus musculus) PubMed

 25483.

A novel fentanyl binding site was identified within the GLIC that results in conformational changes that inhibit conduction through the channel. [GLIC] (Mus musculus) PubMed

 25484.

Disruption of SpoIIID protein results in a sporulation defects. Disruption of SpoIIID increases extracellular proteolytic activity of Bacillus anthracis. Disruption of SpoIIID increases virulence of Bacillus anthracis in mice. [SpoIIID protein] (Mus musculus) PubMed

 25485.

Our in vitro assays document the capability of lipid droplets-accumulated Pgc1 to degrade phosphatidylglycerol upon entry to the membranes of the endoplasmic reticulum, mitochondria and even of artificial phospholipid vesicles [Pgc1]. (Mus musculus) PubMed

 25486.

Propagation of the Allosteric Signal in Phosphofructokinase from Bacillus stearothermophilus [phosphofructokinase] (Mus musculus) PubMed

 25487.

A crystal structure of flagellar capping protein FliD from Helicobacter pylori at 2.6A resolution presents a four-domain (D2-D5) structure, where the D3 domain forms a central platform surrounded by the other three domains (D2, D4, and D5). [flagellar capping protein FliD] (Mus musculus) PubMed

 25488.

The influenza M2 proton channel is therapeutically targetable. This study identified two packing defects in the protein subunits that predict exactly the low and high-affinity drug-binding sites. The latter defect frustrates water coordination, enhancing water basicity and stabilizing the nearby hydronium that forms upon proton penetration in the channel. [M2 proton channel ] (Mus musculus) PubMed

 25489.

Banana MaBZR1/2 interact with MaMPK14 to enhance the transcriptional inhibition of cell wall modifying genes including MaEXP2, MaPL2 and MaXET5 (BZR1, BZR2 and MPK14). (Mus musculus) PubMed

 25490.

This study used X-ray reflectivity (XR) and grazing-incidence X-ray diffraction (GIXD) to investigate how binding of B-subunit of bacterial Shiga toxin (STxB) to Gb3 alters lipid order in gel phase monolayers maintained at a surface pressure of 30 mN/m. STxB compresses lipid packing in a gel phase monolayer upon binding to its cellular receptor, the glycolipid Gb3. [STxB] (Mus musculus) PubMed

 25491.

The authors show that BadA is required for optimal adhesion, agglutination and biofilm formation.[BadA] (Mus musculus) PubMed

 25492.

The results indicate that although both hupA and hvtA are involved for optimal hemin uptake in Vibrio vulnificus, their expression is dually regulated by the environmental cues of iron concentration and temperature.[hvtA] (Mus musculus) PubMed

 25493.

This study sheds light on a novel link between the Msn2-mediated global stress response and the amino acid homeostasis in S. cerevisiae [MSN2]. (Mus musculus) PubMed

 25494.

OsSIRH2-14 E3 ligase regulates OsHKT2 via the 26S proteasome system under high NaCl concentrations but not under normal conditions. (OsSIRH2-14 E3 ligase ) (Mus musculus) PubMed

 25495.

methylation of the C-terminal lysine allows a precise allosteric tuning of Hsp90 activity via long distances.[HSP90] (Mus musculus) PubMed

 25496.

A 117-base pair SARS-CoV-2 orf1b sequence matched a sequence in the human genome with 94.6% identity. The sequence was in chromosome 1p within an intronic region of the netrin G1 (NTNG1) gene. The SARS-CoV-2 human sequence lies within non-structural proteins 14 and 15 (NSP14 and NSP15), and is quite close to the viral spike sequence, separated only by NSP16, a 904-base pair sequence. (Mus musculus) PubMed

 25497.

SARS-CoV-2 nsp13, nsp14, nsp15 and orf6, but not orf8, could potently suppress primary interferon production and interferon signalling. [nsp13, nsp14, nsp15] (Mus musculus) PubMed

 25498.

Decrease in DNA methylation 1 interacts with chromomethylase and like heterochromatin protein 1 in Physcomitrella patens [DMM1][LHP1] (Mus musculus) PubMed

 25499.

rpoX was highly expressed in response to high temperature and low osmotic stress and was under the direct control of the alternative sigma factor RpoE and its own product RpoX. Moreover, transcriptome sequencing (RNA-seq) results showed that RpoE and RpoX had different regulons, although they coregulated 105 genes at high temperature (42 degrees C). [rpoX] (Mus musculus) PubMed

 25500.

lnc403 affects skeletal muscle cell differentiation by affecting the expression of nearby genes and interacting proteins, implying lnc403 might participate in the bovine myoblasts differentiation through multi-pathway network regulation mode (lnc403). (Mus musculus) PubMed

 25501.

This study found that Staphylococcus aureus surface protein clumping factor A (ClfA)-Fibrinogen-Integrin alphaVbeta3 ternary complex is extremely stable, being able to sustain forces ( approximately 800 pN) that are much stronger than those of classical bonds between integrins and the Arg-Gly-Asp (RGD) tripeptide sequence ( approximately 100 pN). [ClfA] (Mus musculus) PubMed

 25502.

Crystal structure of Mokola virus glycoprotein in its post-fusion conformation. (Mus musculus) PubMed

 25503.

The results here provide the first evidence that either HaABCC2 or HaABCC3 protein is sufficient to confer substantial susceptibility to Cry1Ac. The functional redundancy of these two proteins in toxicity of Cry1Ac to H. armigera is expected to reduce the likelihood of field-evolved resistance relative to disruption of a toxic process where mutations affecting a single protein can confer resistance. (Mus musculus) PubMed

 25504.

We showed that OxiR can specifically modulate isoniazid susceptibility by regulating an oxidoreductase encoding gene, both of which have not been associated with drug-resistance previously [OxiR]. (Mus musculus) PubMed

 25505.

NosP/NahK promotes biofilm formation through inhibition of H-NOX/HnoK signaling, which itself reduces the extent of biofilm formation.[NosP] (Mus musculus) PubMed

 25506.

OsIPPI1 mRNA was more abundant than OsIPPI2 mRNA in all tissues, and its expression in de-etiolated leaves mirrored the accumulation of phytosterols, suggesting a key role in the synthesis of mevalonate pathway isoprenoids.The detection of both OsIPPI isoforms in the endoplasmic reticulum indicates that DMAPP can be synthesized de novo in this compartment. (OsIPPI1,2) (Mus musculus) PubMed

 25507.

Aci01347 is the carnitine transporter mediating the first step in the growth of A. baumannii on carnitine.[Aci01347] (Mus musculus) PubMed

 25508.

the study identifies a novel pro-fibrotic lncRNA, PCFL, and the mechanism involves the direct interaction of PCFL with miR-378, which in turn relieves the inhibition effect of miR-378 on GRB2 and promotes cardiac fibrosis. (Mus musculus) PubMed

 25509.

The crystal structure of isolated HigA from Escherichia coli str. K-12 has been determined to 2.0A resolution. The structural differences between HigA and HigA in HigBA complex imply that HigA undergoes drastic conformational changes upon the binding of HigB. [HigA, HigB] (Mus musculus) PubMed

 25510.

(gene: Methane Monooxygenase) Methane Monooxygenase structure and mechanism of action was characterized here (REVIEW) (Mus musculus) PubMed

 25511.

a physiological role for ExtI as a selenite channel associated with ExtH in the outer membrane, is reported.[Extl, ExtH] (Mus musculus) PubMed

 25512.

The structural and functional studies demonstrate that, unlike the single-protein spike composition of other type VI secretion system subtypes, Francisella T6SS's central spike is formed by two proteins, PdpA and VgrG. [PdpA]; [VgrG] (Mus musculus) PubMed

 25513.

The coordination of Cu(ii) ions by the Ac-KGHGNGEEGTPTVHNE-NH2 (1L) peptide - a FomA protein fragment of Fusobacterium nucleatum- and its cyclic analogue: cyclo(KGHGNGEEGTPTVHNE) (2L) was studied by potentiometric titration, spectroscopic methods (UV-Vis, CD, EPR) and mass spectrometry (MS). [FomA] (Mus musculus) PubMed

 25514.

The collective results indicate an important role for the Tgs1 protein of M. marinumin progression of infection in the natural host. Tgs1 signaling may be involved in a previously unknown behavior of M. marinum under hypoxia/aerobiosis [Tgs1]. (Mus musculus) PubMed

 25515.

Interaction of the lettuce tail-anchored NAC transcription factor, LsNAC069, with B. lactucae effectors does not require the N-terminal NAC domain but depends on the C-terminal region including the transmembrane domain. (Mus musculus) PubMed

 25516.

Structural and functional analyses of the lipase CinB from Enterobacter asburiae [CinB] (Mus musculus) PubMed

 25517.

A polymorphism in Helicobacter pylori neutrophil-activating protein A (NapA) closely associated with dyspepsia occurrence was identified. [gene: neutrophil-activating protein A (NapA)] (Mus musculus) PubMed

 25518.

FstC of Aeromonas salmonicida subsp. salmonicida is the receptor for amonabactin siderophore. [FstC] (Mus musculus) PubMed

 25519.

Phosphorylation of ZmC4-NADP-ME drastically decreases its activity as shown by the low residual activity of the recombinant phosphomimetic mutant. Analysis of the crystal structure of C4-NADP-ME indicated that Ser419 is involved in the binding of NADP at the active site. Molecular dynamics simulations indicates a less favorable binding of the cofactor NADP in the phosphomimetic and the phosphorylated variants. (Mus musculus) PubMed

 25520.

Our data suggests C. albicans Pseudouridine synthase 7 (Pus7) is important for fungal vigor and may play distinct biological roles than those ascribed to S. cerevisiae Pus7 [Pus7]. (Mus musculus) PubMed

 25521.

OmpB is dispensable for bacterial growth in endothelial cells, it is essential for R. parkeri to block autophagy in macrophages and to colonize mice because of its ability to promote autophagy evasion in immune cells. OmpB acts as a protective shield to obstruct autophagy recognition, thereby revealing a distinctive bacterial mechanism to evade antimicrobial autophagy. (Mus musculus) PubMed

 25522.

we provide a structural basis for TbPRMT1 ENZ activation by PRO heterotetramer formation, which is conserved across all kinetoplastids, and describe a chaperone function of the TbPRMT1 prozyme, which represents a novel mode of PRMT regulation. (Mus musculus) PubMed

 25523.

The intracellular localization of alpha-xylosidase termed AxyA may help determine the order of hydrolases acting on xyloglucan oligosaccharides [AxyA]. (Mus musculus) PubMed

 25524.

Thus, NP disturbs the autophagic degradation of Gn. These findings highlight how hantaviruses repurpose host autophagy and evade innate immune responses for their life cycle and pathogenesis. (Mus musculus) PubMed

 25525.

This study implicates OsERdj7 in the translocation of some seed proteins within the endoplasmic reticulum lumen and in the degradation of misfolded or unfolded proteins. (OsERdj7) (Mus musculus) PubMed

 25526.

The apo 65-kDa amino-terminal fragment of DNA topoisomerase I from the gram-positive model organism Streptococcus mutans was crystalized and a three-dimensional structure was determined to 2.06A resolution via x-ray crystallography.[Topoisomerase I] (Mus musculus) PubMed

 25527.

Variation in the promoter region of the HECT E3 ligase gene BnaUPL3 C03 made a major contribution to variation in seed weight per pod, with accessions exhibiting high seed weight per pod having lower levels of BnaUPL3 C03 expression. (BnaUPL3 C03 ) (Mus musculus) PubMed

 25528.

This study suggests the involvement of rolB in photosynthesis modulation under far-red-rich light in tomato. (Agrobacterium rhizogenes rolB gene) (Mus musculus) PubMed

 25529.

The ability of a single allele of Hsh155 to perturb interactions with multiple factors functioning at different stages of the splicing reaction suggests that some SF3b1-mutant disease phenotypes may have a complex origin on the spliceosome.[Hsh155] (Mus musculus) PubMed

 25530.

Trichinella spiralis ASP2 possesses the enzymatic activity of native aspartic protease and facilitates Trichinella spiralis invasion of host intestinal epithelial cells. (Mus musculus) PubMed

 25531.

Structural analysis revealed several highly conserved residues in the putative ligand binding grooves of HisE and HisI, showing an evolutionarily conserved catalytic mechanism shared among gram negative-bacteria.[Hisl, HisE] (Mus musculus) PubMed

 25532.

both LmFH-1 and LmFH-2 are susceptible to oxygen-dependent inhibition since oxygen exposure converts an active [4Fe-4S] cluster to an inactive [3Fe-4S] cluster.[LmFH-1 and LmFH-2] (Mus musculus) PubMed

 25533.

The molybdenum-dependent nitrogenase consists of two component proteins: the molybdenum-iron protein (MoFeP) and the iron protein. The utility of a sulfonated viologen derivative as an electron donor for nitrogenase was demonstrated. [MoFeP protein, iron protein] (Mus musculus) PubMed

 25534.

In Nicotiana benthamiana (Nb), PAD4 demonstrated no detectable immune functions, but TNL-mediated resistance responses required EDS1 complexes incorporating a SENESCENCE ASSOCIATED GENE101 (SAG101) isoform. (EDS1) (Mus musculus) PubMed

 25535.

Potato (Solanum tuberosum) mutant lacking one isoform of manganese-stabilizing protein (MSPI) of photosystem II exhibited besides spontaneous tuberization also growth changes with strongly impaired root system development. (MPSI) (Mus musculus) PubMed

 25536.

Recombinant Plasmodium falciparum SUB1-ProM was found to be a fast-binding, potent inhibitor of P. falciparum SUB1, but not of the only other essential blood-stage parasite subtilase, SUB2, or of other proteases examined. Mass-spectrometry and immunofluorescence showed that SUB1-ProM is expressed in the PV of blood stage P. falciparum, where it may act as an endogenous inhibitor to regulate SUB1 activity in the parasite. (Mus musculus) PubMed

 25537.

Biochemical and structural analysis of the Klebsiella pneumoniae cytidine deaminase CDA; KpCDA might be a potential antibacterial target for the disease caused by K. pneumoniae (Mus musculus) PubMed

 25538.

ChiE1- or ChiIII-reconstituted heat-inactivated stipe walls showed maximal extension activity at pH 4.5, consistent with the optimal pH for native stipe wall extension in vitro; enzyme stipe wall extension activities were associated with stipe elongation growth regions; the combination of ChiE1 and ChiIII showed a synergism to reconstitute heat-inactivated stipe wall extension at a low action concentration. [ChiE1,ChiIII] (Mus musculus) PubMed

 25539.

VvWRKY26 enhances the expression of selected target genes induced by VvMYB5a/b. (VvMYB5) (Mus musculus) PubMed

 25540.

In this study we determined that the unique prokaryotic peptidylarginine deiminase (PPAD) has a significant impact on P. gingivalis strain 381 biofilm formation, a key feature of the bacterium's ability to persist and cause disease [PPAD]. (Mus musculus) PubMed

 25541.

Based on amino acid sequence and phylogenetic analyses, two new silkworm Bombyx mori sulfotransferase (SULT) enzymes, swSULT ST1 and swSULT ST2, were identified that appear to belong to a distinct group of SULTs. swSULT ST1 may play a role in the detoxification of xenobiotics, including insecticides, in the silkworm midgut and in the induction of gametogenesis in silkworm ovary and testis. (Mus musculus) PubMed

 25542.

Emit1 and Emit2 act coordinately to import Med into the MIC, and Rib1 recruits the Mediator complex to specific chromosomal locations to quantitatively or qualitatively promote the biogenesis of functional ncRNA. [Emit1,Emit2,Rib1] (Mus musculus) PubMed

 25543.

CagW, the VirB6 homologue, interacts with the substrate of the secretion system CagA (CagW,CagA). (Mus musculus) PubMed

 25544.

This is the first report on PadR regulators to regulate the type III secretion system.[PadR] (Mus musculus) PubMed

 25545.

Quorum sensing and the anaerobic regulator (ANR) control polyhydroxyalkanoate (PHA) production in Pseudomonas chlororaphis PA23. [ANR] (Mus musculus) PubMed

 25546.

A strong correlation between ertapenem resistance and AcrA overexpression is observed in Escherichia coli. Imipenem stress increases AcrB expression. The transcription of AcrR is insistently increased which is much higher than the transcriptional level of AcrA under concentration gradient carbapenem stress condition. AcrAB pump has an important role in developing resistance against carbapenem group of antibiotics. (Mus musculus) PubMed

 25547.

Acetate and nutrients are capable of synergistically activating SPI-1 gene expression in Salmonella enterica serovar Typhimurium. These signals are found to tune the fraction of cells expressing the SPI-1 genes. The governing mechanism involves transcriptional crosstalk with the flagellar gene network. (Mus musculus) PubMed

 25548.

Structure and product relationship analysis of acyl homoserine lactone synthases (LuxI) among Ensifer adhaerens reveals distinct chromosome and plasmid origins. [LuxI] (Mus musculus) PubMed

 25549.

this study shows that particulate Shiga Toxin 2 in blood is associated to the development of hemolytic uremic syndrome in children (Mus musculus) PubMed

 25550.

tumour beclin 1 expression is inversely associated with the amount of F. nucleatum in colorectal cancer tissue (Mus musculus) PubMed

 25551.

The lack of FtsH1/3 leads to a drastic reduction in the transcriptional response to nutrient stress of not only Fur but also the Pho, NdhR, and NtcA regulons. ( FtsH1, FtsH3) (Mus musculus) PubMed

 25552.

Bombyx mori GrpE (BmGrpE) is highly expressed under high-temperature stress. RNAi of BmGrpE reduces BmN cell viability under stress conditions. Mutation of BmGrpE (H163L) enhances BmN thermal resistance. (Mus musculus) PubMed

 25553.

Transferrin receptor diversification is driven by a need for antigenic variation in the receptor to prolong survival in a host. [transferrin receptor] (Mus musculus) PubMed

 25554.

The authors have shown that, compared to wild-type, a quadruple mutant is significantly more sensitive to hydrogen peroxide, has a lower minimum bactericidal concentration to the cationic antimicrobial peptide polymyxin B, and is attenuated in macrophages. (Mus musculus) PubMed

 25555.

The authors found that the transcriptionally independent suppression of CXCL10 is mediated by the virulence factor and protease, glycoprotein-63 (gp63) of Leishmania major. Specifically, GP63 cleaves CXCL10 after amino acid A81 at the base of a C-terminal alpha-helix. (Mus musculus) PubMed

 25556.

Our results have shown that specific amino acid residues along the H domain, as well as the R domain, are essential for the toxicity of the AapA1 toxin. (Mus musculus) PubMed

 25557.

A plant xanthophyll acyltransferase (XAT) that is both necessary and sufficient for xanthophyll esterification in bread wheat grain. XAT contains a canonical Gly-Asp-Ser-Leu (GDSL) motif and is encoded by a member of the GDSL esterase/lipase gene family. (xanthophyll acyltransferase ) (Mus musculus) PubMed

 25558.

These findings reveal the roles of BOH1 in maintaining hook-complex morphology and regulating flagellum inheritance, and establish BOH1 as an upstream regulator of the TbPLK-mediated cytokinesis regulatory pathway.[BOH1, TbPLK1] (Mus musculus) PubMed

 25559.

results indicate that the association of PUR proteins with circSamd4 enhances myogenesis by contributing to the derepression of MHC transcription (circSamd4). (Mus musculus) PubMed

 25560.

Because Borrelia burgdorferi sensu lato lacks the enzymes required for de novo purine synthesis, BmpD may play a vital role in ensuring access to the purines needed to sustain an infection in the host.[BmpD] (Mus musculus) PubMed

 25561.

Inactivated C16L gene of Vaccinia virus[ enhances replication in numerous human cell lines. [C16L ] (Mus musculus) PubMed

 25562.

Loss of function of ALDH2B1 greatly enhanced resistance to broad-spectrum pathogens, including fungal blast, bacterial leaf blight, and leaf streak.[ALDH2B1] (Mus musculus) PubMed

 25563.

The data suggest that lncRNA Oplr16 may act as a pivotal chromatin factor to control stem cell fate by modulating chromatin architecture and DNA demethylation (Oplr16). (Mus musculus) PubMed

 25564.

Alr1240, a RNase II family member, bound to the catalytic domain of RNase E and this interaction could influence the catalytic activity of RNase E (Alr1240). (Mus musculus) PubMed

 25565.

The importance of MYST family histone acetyltransferase as a developmental regulator, is reported.[MoSAS3] (Mus musculus) PubMed

 25566.

Study systematically compared the interactions of adenovirus-associated RNA 1 (VAI) and Epstein-Barr virus noncoding RNA, EBER1, with PKR and developed a structural model of EBER1. Results revealed that EBER1 weakly activates PKR whereas VAI does not. The central stem of EBER1 coaxially stacks with stem loop 4 and stem loop 1 to form an extended RNA duplex of approximately 32 bp that binds PKR and promotes activ...[EBER1] (Mus musculus) PubMed

 25567.

A putative stand-alone EAL domain phosphodiesterases from Vibrio cholerae (EAL) is capable to degrade both the second messenger c-di-GMP and hybrid 3'3'-cyclic GMP-AMP (cGAMP). [EAL] (Mus musculus) PubMed

 25568.

Genetic diversity and Structural analysis in the nsp12 gene. (Mus musculus) PubMed

 25569.

recombinant Trichinella spiralis-GST decreased the LPS-induced elevated level of pro-inflammatory cytokines of dendritic cells and enhanced the level of regulatory cytokines IL-10 and TGF-beta. [Glutathione-S-transferase] (Mus musculus) PubMed

 25570.

This study determined the crystal structure of FeoA from the nosocomial agent Klebsiella pneumonia. The structure reveals an SH3-like domain that mediates interactions between neighboring polypeptides via hydrophobic intercalations into a Leu-rich surface ridge. [FeoA] (Mus musculus) PubMed

 25571.

In vivo evaluation of Shigella virulence uncovered a strong correlation between type three secretion system effector protein secretion, host cell membrane disruption, and cellular invasion by the tested mutant strains, suggesting that perturbation of the identified interfacial residues/interactions influences Spa47 activity through preventing oligomer formation, which in turn regulates Shigella virulence. [Spa47] (Mus musculus) PubMed

 25572.

Using allelic replacement in Plasmodium berghei, we show that the alveolin domain is responsible for targeting IMC1h to the membrane skeleton and, consequently, its deletion from the protein results in loss of function manifested by abnormally-shaped ookinetes and sporozoites with reduced tensile strength, motility and infectivity.[IMC1h] (Mus musculus) PubMed

 25573.

The PhoPQ two component system governs the activation of K. pneumoniae T6SS in bacterial competitions. [PhoQ, PhoP] (Mus musculus) PubMed

 25574.

The C-terminal domain of Hp0897 (Hp0897CTD) shows stronger interaction with HpDnaB over the N-terminal region of Hp0897.[Hp0897] (Mus musculus) PubMed

 25575.

Here we report the structure of LepI in complex with SAM as its co-factor, which adopts a typical class I methyltransferase fold. Docking studies are performed to investigate the binding modes of various substrates/products and provide insights into the catalytic mechanism of the multiple reactions catalyzed by LepI. (Mus musculus) PubMed

 25576.

Mutational analysis of TriMV P1 suggested functional roles for these motifs in suppression of RNA silencing [P1]. (Mus musculus) PubMed

 25577.

These results indicated that Nfa34810 is a virulence factor of Nocardia farcinica and plays an important role during infection. Nfa34810-induced production of TNF-alpha in macrophages also involves ERK, JNK, and NF-kappaB via the TLR4 pathway. (Mus musculus) PubMed

 25578.

Recombinant lactate dehydrogenase 1 (LDH-1) has an optimum pH of 7.5 and is stable between pH 8.0 and 9.0; pH data analysis showed two pKa values of 6.1+/-0.15 and 8.8+/-0.15 suggesting a histidine and asparagine, respectively, involved in the active site. The enzyme optimal temperature was 44 degrees C and it was stable between 20 and 60 degrees C. (LDH-1) (Mus musculus) PubMed

 25579.

the roles of DksA and guanosine pentaphosphate in the virulence traits of Xanthomonas citri subsp. citri (Xcc), the causal agent of citrus canker.[DksA] (Mus musculus) PubMed

 25580.

FgbioH1 had an inversely correlated pattern of expression to that of Fgmil-2 and FgDicer2.[Fgmil-2, bioH1] (Mus musculus) PubMed

 25581.

Here, the authors used in vivo pattern analysis of conditional essentiality (PACE) and identified that ftsH and hflK/C were associated with impaired in vivo colonization in Edwardsiella piscicida and attenuated internalization ability of ZF4 cells.[ftsH] (Mus musculus) PubMed

 25582.

data provide pivotal evidence that the formation of intermolecular disulfide bonding between Cys(124) and Cys(128) plays a critical role in structural assembly of a biologically active-TlyA oligomer [TlyA] (Mus musculus) PubMed

 25583.

Mutation of K100 of N-terminal DNA-binding domain significantly reduces the affinity of Cdc5 to a Cdc5-binding element. [cdc5] (Mus musculus) PubMed

 25584.

oqxAB-positive incHI2 plasmid pHXY0908 increases Salmonella enterica serotype Typhimurium strains tolerance to ciprofloxacin. [oqxA], [oqxB] (Mus musculus) PubMed

 25585.

the deletion of MHY1 in Y.lipolytica is a reliable way of abolishing hyphae formation with few detectable negative side effects regarding growth, stress tolerance and lipid accumulation and composition.[MYH1] (Mus musculus) PubMed

 25586.

results reveal several structural determinants of LPMO substrate specificity and underpin the notion that productive substrate binding by these enzymes is complex, depending on a multitude of amino acids located on the substrate-binding surface [LPMO] (Mus musculus) PubMed

 25587.

FttA is a CPSF73 human homologue that terminates transcription in Archaea. [FttA] (Mus musculus) PubMed

 25588.

These results suggest that VP19 is essential for WSSV envelope coating VP19]. (Mus musculus) PubMed

 25589.

This study suggests that the GL6 protein may be involved in the intracellular trafficking of cuticular waxes, opening the door to elucidating the poorly understood process by which cuticular wax is transported from its site of biosynthesis to the plasma membrane. [GL6] (Mus musculus) PubMed

 25590.

An extracellular loop sequence of PIP1;3 and the alpha-helix motif of Hpa1 determine both the molecular interaction and its consequences with respect to the effector translocation and the bacterial virulence on the susceptible rice variety. [hpa1] (Mus musculus) PubMed

 25591.

circ-0114427 bound to miR-494 as a miRNA sponge to regulate ATF3 expression and further affected the expression of downstream cytokine IL-6.[circ_0114427] (Mus musculus) PubMed

 25592.

This study uncovered a novel antisense lncRNA (Bhmt-AS) that is co-expressed with Bhmt and concordantly and specifically regulates Bhmt expression both in vitro and in vivo to regulate hepatic gluconeogenesis. [Bhmt-AS] (Mus musculus) PubMed

 25593.

A novel mcr-3.19 was identified along with mcr-1 contained in a hybrid plasmid; this finding suggested that evolution of mcr genes among various plasmids was being driven by mobile elements.[MCR-1; MCR-3] (Mus musculus) PubMed

 25594.

This review summarizes the structure and functions of OmpA in A. baumannii (AbOmpA), collects novel therapeutic strategies against it for treating A. baumannii infection, and emphasizes the feasibility of using AbOmpA as a potential therapeutic target. [OmpA] (Mus musculus) PubMed

 25595.

This study reports the crystal structure of trans-3-Hydroxy-l-proline (T3LHyp) from the archaea Thermococcus litoralis in the free and substrate-complexed form. [trans-3-Hydroxy-l-proline] (Mus musculus) PubMed

 25596.

results support a mechanism in which direct interactions with phosphatidylinositol-containing lipids play an essential role in targeting ExoU to host membrane bilayers; molecules or peptides that block this interaction may prove useful in preventing the cytotoxic effects of ExoU to mitigate the virulence of P. aeruginosa strains that express this potent phospholipase toxin [ExoU] (Mus musculus) PubMed

 25597.

Isogenic mutant strains in which genes encoding R28 or transcriptional regulator Spy1337 are inactivated are significantly less virulent in a model of necrotizing myositis (R28,Spy1337) . (Mus musculus) PubMed

 25598.

The cytoplasmic domain of MxiG interacts with MxiK and directs assembly of the sorting platform in the Shigella type III secretion system [MxiG & MxiK] (Mus musculus) PubMed

 25599.

LITAF acts as an adaptor protein promoting NEDD4-mediated ubiquitination and subsequent degradation of L-type calcium channel.[NEDD4] (Mus musculus) PubMed

 25600.

SULT2B interferes with AKR1C3 upregulation and castration-resistant prostate cancer cell progression to increased aggressive traits such as enhanced androgen receptor activity, activation of ERK1/2, induction of an EMT-like state, and acceleration of xenograft tumor growth. [AKR1C3] (Mus musculus) PubMed

 25601.

Saccharomyces cerevisiae cell wall can induce SBD-1 expression and this induction is regulated by the TLR2-MyD88-NF-kappaB pathway. [SBD-1] (Mus musculus) PubMed

 25602.

degradation of PsbS is essential in the fully high light acclimated state.[PsbS] (Mus musculus) PubMed

 25603.

RiCE17 exclusively removes the axially oriented 2-O-acetylations on any mannose residue in an oligosaccharide, including double acetylated mannoses, while the RiCE2 is active on 3-O-, 4-O-, and 6-O-acetylations. [RiCE 17; RiCE2] (Mus musculus) PubMed

 25604.

Study determined crystal structures of Tetrahymena thermophila Lipin/Pah phosphatidic acid phosphatase Pah2 (Tt Pah2) that directly fuses two conserve regions (N-Lip and C-Lip). Tt Pah2 adopts a two-domain architecture where the N-Lip combines with part of the C-Lip to form an immunoglobulin-like domain and the remaining C-Lip forms a HAD-like catalytic domain.[Pah2] (Mus musculus) PubMed

 25605.

The ligand binding of CarR induces its dissociation from the carR-uspA promoter to derepress carR and uspA transcription. [CarR] (Mus musculus) PubMed

 25606.

XgDeltaavrHah1 differentially up-regulates 2 basic helix-loop-helix transcription factors with predicted effector binding elementsfor AvrHah1. These target a pectate lyase and pectinesterase. By perturbing transcriptional networks and/or modifying the plant cell wall, AvrHah1 may promote water uptake to enhance tissue damage and bacterial egression from the apoplast to the leaf surface. Avr. (Mus musculus) PubMed

 25607.

[lncRNA-Gas5] YY1 interacts with LncRNA GAS5 to promote PFKFB3 transcription to enhance neuronal glycolysis, resulting in aggravating cerebral I/R injury. (Mus musculus) PubMed

 25608.

The results provided clues for understanding the CncC/keap1 pathway-mediated regulation of metamorphosis of Lepidopteran insect Bombyx mori. (KEAP1 Protein) (Mus musculus) PubMed

 25609.

TOR repression, under C-limited conditions, leads to a significant reduction in the Carbon/Nitrogen ratio.[TOR] (Mus musculus) PubMed

 25610.

Cis-prenyltransferases MM_0014, MM_0618, and MM_1083 are responsible for the biosynthesis of glycosyl carrier lipids, such as di- and tetra-hydrogenated decaprenyl phosphates.[MM_0014][ MM_0618][MM_1083] (Mus musculus) PubMed

 25611.

The crystal structure of the SepF-FtsZ complex reveals a hydrophobic FtsZ-binding pocket, which defines the SepF homodimer as the functional unit.[SepF, FtsZ] (Mus musculus) PubMed

 25612.

RBT-1 mediated the uptake of Cry6Aa into C. elegans gut cells, and was shown to be involved in triggering pore-formation activity, indicating that RBT-1 is required for the interaction of Cry6Aa with the nematode midgut cells. These results support that RBT-1 is a functional receptor for Cry6Aa. (Mus musculus) PubMed

 25613.

indings challenge present views on the relationship of IE1 with PML and the role of PML in hCMV replication. This study also provides initial evidence for the idea that disruption of PML bodies upon viral infection is linked to activation rather than inhibition of innate immunity. (Mus musculus) PubMed

 25614.

EhC2B acts like a molecular bridge which promotes membrane deformation via its actin nucleation activity during the progression of the phagocytic cup in a calcium-dependent manner. (Mus musculus) PubMed

 25615.

CdbA acts as a nucleoid-associated protein that contributes to chromosome organization and is modulated by Cyclic di-GMP.[CdbA] (Mus musculus) PubMed

 25616.

Taken together, the results show that the L. casei Zhang pglX gene is a functional adenine MTase that belongs to the bacteriophage exclusion (BREX) system. [pglX] (Mus musculus) PubMed

 25617.

Study shows that the two ubiquitin associated (UBA)-like domains present towards the end of the tail region in Myo21 mostly determine its prominent localization to the flagellum base, and perhaps also its involvement in the flagellum assembly and cell division. [Myo21] (Mus musculus) PubMed

 25618.

NS5A: identified a new protein kinase that regulates a delicate balance of NS5A between hypo- and hyper-phosphorylation states, respectively, involved in host antiviral responses and liver cancer progression.[NS5A] (Mus musculus) PubMed

 25619.

The T164S mutant virus decreased infectious virus production and increased secreted NS1 production.[NS1] (Mus musculus) PubMed

 25620.

Overall, the strategy employed in the present work resulted in the retrieval of seven candidates that may show inhibitory activity against PfDHFR and could be further exploited as a scaffold to develop novel antimalarials (Mus musculus) PubMed

 25621.

These findings reveal that YopH prevents activation of both SKAP2-dependent and -independent neutrophilic defenses, uncouple integrin- and GPCR-dependent ROS production from FcgammaR responses based on their SKAP2 dependency, and show that SKAP2 is not required for degranulation. (Mus musculus) PubMed

 25622.

A LOG homologue, SiRe_0427, from the hyperthermophilic archaeon Sulfolobus islandicus REY15A, possessed the LOG motif GGGxGTxxE and exhibited phosphoribohydrolase activity on adenosine-5-monophosphate (AMP), similar to LOGs from eukaryotes and bacteria. Alanine mutants at either catalytic residues or substrate binding sites lost their activity, resembling other known LOGs. [SiRe_0427] (Mus musculus) PubMed

 25623.

VqmA crystal structure reveals that Cys134 disulfide bond serves as a switch for conformations of VqmA.VqmA DNA binding domains were covalently linked by a disulfide bond formed by the highly conserved Cys134. [VqmA] (Mus musculus) PubMed

 25624.

analysis of intrinsically disordered inhibitor IF7 of glutamine synthetase in isolation and in complex with its partner [IF7] (Mus musculus) PubMed

 25625.

data identify GRA24 as a major mediator of p38 MAPK activation, IL-12 induction and protective immunity that operates independently of the TLR/MyD88 cascade. (Mus musculus) PubMed

 25626.

Inability of the Isocitrate dehydrogenase (ICDH)-less strain to utilize acetate as a source of carbon, despite the presence of elevated levels of acetate kinase (AK) and phosphotransacetylase (PTA), has been elaborated upon in the light of recent findings (ICDH) . (Mus musculus) PubMed

 25627.

This is the first report demonstrating that ctsR gene enhances the acid-ethanol tolerance of L. plantarum [ctsR]. (Mus musculus) PubMed

 25628.

RSc1154 and RhlE were predicted to be temperature-related pathogenic genes for R. solanacearum in tomato [RhlE]. (Mus musculus) PubMed

 25629.

This study establishes that GRA16 is a HAUSP inhibitor that targets the nuclear localization of PTEN and induces the anticancer effect in a p53-dependent manner. The efficacy of GRA16 could be newly highlighted in hepatocellular carcinoma (HCC) treatment in a p53-dependent manner (Mus musculus) PubMed

 25630.

the fast skeletal muscle myosin II isoform myosin heavy chain (MHC-IID) can be transformed into a processive motor, by simply replacing the native regulatory light chain MLC2f with the regulatory light chain variant MLC2v from the slow muscle myosin II.[myosin II] (Mus musculus) PubMed

 25631.

Study reports the crystal structure of acyl-acyl carrier protein reductase (AAR) from Synechococcus elongatus PCC 7942 (SeAAR) in its apo form (AARapo), together with three structures of AAR in complex with aldehyde-deformylating oxygenase (ADO) from the same species of cyanobacteria (SeADO), in which AAR binds either substrate or substrate/cofactor. [AAR] (Mus musculus) PubMed

 25632.

Study demonstrated that the homeobox transcription factor Hob1 is the master regulator for a number of brain-infection-related genes in the C. neoformans H99 strain, causative agent of fatal fungal meningoencephalitis, but not in the Cryptococcus deuterogattii R265 strain that does not target the brain during infection.[Hob1] (Mus musculus) PubMed

 25633.

Crystal structure of CDD-1 beta-lactamase show a unique substrate-binding mode. [CDD-1 beta-lactamase] (Mus musculus) PubMed

 25634.

The crystal structure of the omega-transaminase provided insights into the substrate specificity.[omega-transaminase] (Mus musculus) PubMed

 25635.

We found a novel protein, phosphoenolpyruvate synthetase-like (PPS-like), which exhibited high homology to PPS enzyme. Deletion of PPS-like gene in an EPS-deficient strain had an added effect on the poly(3-hydroxybutyrate-co-3-hydroxyvalerate) accumulation [ PPS-like [HFX_2676]. (Mus musculus) PubMed

 25636.

Study identified and characterized two in-frame proteins encoded by overlapping genes (OGs) on plasmid pIGRK from Klebsiella pneumoniae. Two functional polypeptides: a full-length RepR protein and a RepR' protein (with N-terminal truncation) translated from an internal START codon but with antagonistic functions. [RepR, RepR'] (Mus musculus) PubMed

 25637.

GhAAI66 was preferentially expressed in flower tissue and as responses to phytohormone treatments. Ectopic expression of GhAAI66 in Arabidopsis and silencing in cotton revealed that GhAAI66 triggers a phase transition to induce early flowering. [AAI66] (Mus musculus) PubMed

 25638.

study provide insights for understanding the catalytic mechanism of EGALC[EGALC] (Mus musculus) PubMed

 25639.

CytR is a modulator of bacterial internalization and aggregation within the bladder epithelial cells sustained by cyclic-AMP receptor protein (CRP) in Uropathogenic Escherichia coli. [CytR] (Mus musculus) PubMed

 25640.

a model of complex between APRT from Thermus thermophilus strain HB27 and its natural ligands: PRPP and magnesium cation, is reported.[APRT] (Mus musculus) PubMed

 25641.

Results present evidence that RgsD attenuates cAMP-PKA signaling pathway and negatively regulates asexual development, toxigenesis, melanin production, and virulence in Aspergillus fumigatus. [RgsD ] (Mus musculus) PubMed

 25642.

Organellar restructuring during zygotic diploidization does not occur by default but is triggered by a combinatorial switch, the GSM1/GSP1 dyad. This switch may represent an ancient mechanism that evolved to restrict genetic recombination during sexual development. (GSM1) (Mus musculus) PubMed

 25643.

AKR and AIN have additive effects on the bluegreen aphid (BGA) resistance phenotype. However, AKR exerts dominant suppression epistasis on AIN-controlled macroscopic necrotic lesions. Nevertheless, both AKR and AIN condition production of H2O2 at the BGA feeding site. [AKR,AIN] (Mus musculus) PubMed

 25644.

Findings indicate that yogurt starter strains Streptococcus thermophilus 1131 and Lactobacillus delbrueckii subsp. bulgaricus 2038 induced the expression of Reg3g in mice, and have the potential to maintain and improve intestinal barrier function by stimulating immune cells in the lamina propria. (Mus musculus) PubMed

 25645.

Findings indicate that yogurt starter strains Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 induce the expression of Reg3g in mice, and have the potential to maintain and improve intestinal barrier function by stimulating immune cells in the lamina propria. (Mus musculus) PubMed

 25646.

PHS9 encodes a higher plant unique CC-type glutaredoxin and is specifically expressed in the embryo at the late embryogenesis stage, implying that PHS9 plays some roles in the late stage of seed development. PHS9 and OsGAP acted as negative regulators in abscicic acid signaling during seed germination. (Mus musculus) PubMed

 25647.

The overexpression of rice ACYL-CoA-BINDING PROTEIN2 (ACBP2) increases grain size and bran oil content in transgenic rice. (Mus musculus) PubMed

 25648.

Conditional depletion of aga-miR-14 or aga-miR-305,increased mosquito resistance to both Plasmodium falciparum and Plasmodium berghei infection.[aga-miR-14 or aga-miR-305] (Mus musculus) PubMed

 25649.

MALT1 has an ancient role modulating neural circuit function downstream of IL-17 to remodel physiology and behavior.[Il-17] (Mus musculus) PubMed

 25650.

The neuromedin U homolog CAPA-1 and its receptor NMUR-1 are required for the retrieval of learned salt avoidance.[NMUR-1] (Mus musculus) PubMed

 25651.

Ubp6 maintains the level of free ubiquitin to promote the elimination of misfolded cytosolic proteins, while Ubp3 supports the degradation of misfolded cytosolic and ER luminal proteins by different mechanisms.[Ubp3, Ubp6] (Mus musculus) PubMed

 25652.

Study finds miR398 expression downregulated in potatoes during low nitrogen stress and highlights its crucial role in potato during low N stress management. [miR398] (Mus musculus) PubMed

 25653.

MreB double protofilaments can exhibit left-handed twisting that is dependent on the bound nucleotide and membrane binding; the degree of twisting correlates with the length and orientation of MreB filaments. [MreB] (Mus musculus) PubMed

 25654.

This study determined the crystal structure of Lpg0189 at 1.98A resolution by using single-wavelength anomalous diffraction. Lpg0189 folds into a novel chair-shaped architecture, with two sheets roughly perpendicular to each other. [Lpg0189] (Mus musculus) PubMed

 25655.

Study shows that Blp1 protein is encoded in all examined clinical strains from clonal lineages I (IC I) and II (IC II). The two blp1 gene variants exhibit lineage-specific distribution profile. blp1 deletion mutants and their complementation with blp1 alleles show that blp1 gene is required for biofilm formation and virulence phenotype. [Blp1] (Mus musculus) PubMed

 25656.

TaSTP13 is transcriptionally induced and contributes to wheat susceptibility to stripe rust, possibly by promoting cytoplasmic hexose accumulation for fungal sugar acquisition in wheat-Pst interactions. [STP13] (Mus musculus) PubMed

 25657.

Compared with wild-type (WT) plants, transgenic Arabidopsis plants overexpressing TaHDZ5-6A displayed enhanced drought tolerance, lower water loss rates, higher survival rates, and higher proline content under drought conditions.[HDZT-6A] (Mus musculus) PubMed

 25658.

The RNase activity of Csx1 can effectively direct successful anti-plasmid immunity. Cyclic oligoadenylate (cOA) compounds activate the ribonuclease activity of Pfu Csx1. Furthermore, the HEPN domain of the adenosine-specific endoribonuclease, Pfu Csx1, degrades cOA signaling molecules to provide an auto-inhibitory off-switch of Csx1 activation (Csx1). (Mus musculus) PubMed

 25659.

Certain foodborne Shiga toxin-producing Escherichia coli (STEC) strains carry genes encoding the subtilase cytotoxin (SubAB). Transcription of the Subtilase Cytotoxin Gene subAB (1) in Shiga Toxin-Producing Escherichia coli Is Dependent on hfq and hns. (Mus musculus) PubMed

 25660.

the enzyme encoded by the ERED gene in E. ramulus DSM 16296 (KF154735, protein accession number AGS82961) was demonstrated to cleave several flavanones and flavanonols in an NADH-dependent manner [enoate reductase]. (Mus musculus) PubMed

 25661.

HP1454 is a crucial bacterial factor that exerts its proinflammatory activity by directly modulating the T-cell response. (HP1454) (Mus musculus) PubMed

 25662.

Cryo-electron microscopy structure shows that CAP activates transcription by inducing intermediate state.[CAP] (Mus musculus) PubMed

 25663.

The obtained results indicate that BfmR is not only required for the pellicle phenotype induction in A. baumannii, but also, due to the down-regulation of a CDI system, could allow the incorporation of other A. baumannii strains or related species, possibly increasing the likelihood of the pathogens' survival. [BfmR] (Mus musculus) PubMed

 25664.

The C-terminal region of topoisomerase I has higher affinity for ssDNA than the N-terminal active site. This allows the C-terminal domains to capture one strand of underwound negatively supercoiled DNA substrate first and position the N-terminal domains to bind and cleave the opposite strand in the relaxation reaction (topoisomerase I). (Mus musculus) PubMed

 25665.

We demonstrated that P36 is required for resistance to in vitro hydrogen peroxide treatment in Mycobacterium bovis [P36]. (Mus musculus) PubMed

 25666.

We showed that knockout of the Rv2617c gene in M. tuberculosis CDC1551 reduced the replication of the pathogen in a mouse model of infection. We also demonstrated that Rv2617c is required for resistance to in vitro hydrogen peroxide treatment [Rv2617c]. (Mus musculus) PubMed

 25667.

Phase variation of Type III DNA adenine methyltransferase modM3 epigenetically regulates the expression of a phasevarion containing multiple genes that are potentially important in the progression of otitis media [modM3]. (Mus musculus) PubMed

 25668.

Results of this study provide novel insights into MoFap7-mediated orchestration of the development and pathogenesis of filamentous fungi [Fap7]. (Mus musculus) PubMed

 25669.

We have described R-mutants of the atypical species B. microti defective in wkbE (encoding a putative glycosyltransferase involved in lipopolysaccharide (LPS) O-polysaccharide biosynthesis) expression/activity in cellular and in vivo models of infection [wbkE]. (Mus musculus) PubMed

 25670.

L. monocytogenes glutaredoxin plays a counterintuitive role in bacterial oxidative resistance and intracellular infection [glutaredoxin]. (Mus musculus) PubMed

 25671.

In this work, we report that two novel putative proteins, coded by the genes LIC11711 and LIC12587 of L. interrogans serovar Copenhageni are conserved among pathogenic strains, and probably exposed in the bacterial surface [LIC11711; LIC12587]. (Mus musculus) PubMed

 25672.

The data described herein pertaining to the underreporting of 10E8 non-binding gp41 sequences from India, highlight the need for regular national surveillance of circulating molecular clones [GP41]. (Mus musculus) PubMed

 25673.

Our results indicate that BfmS negatively controls the pathogenic traits of A. baumannii via cell envelope structures and OMV production [BfmS]. (Mus musculus) PubMed

 25674.

we verified that mmu_circ_0000250 enhanced the therapeutic effect of ADSC-exosomes to promote wound healing in diabetes by absorption of miR-128-3p and upregulation of SIRT1. Therefore, these findings advocate targeting the mmu_circ_0000250/miR-128-3p/SIRT1 axis as a candidate therapeutic option for diabetic ulcers (Mus musculus) PubMed

 25675.

In this study, we demonstrated, for the first time, that OI-9 encodes a novel transcriptional activator, Z0346 (named OvrB), which is required for bacterial adherence to host cells and locus for enterocyte effacement gene expression in O157 [OvrB]. (Mus musculus) PubMed

 25676.

We established N-acetyltransferase AAC(3)-I as a gentamicin-based selectable marker for oomycete transformation without interference with existing geneticin resistance [N-acetyltransferase AAC(3)-I]. (Mus musculus) PubMed

 25677.

CtcS was characterized as a tetracycline- and Chlortetracycline-responsive MarR family regulator. [CtcS]. (Mus musculus) PubMed

 25678.

Our results revealed crucial roles of the casein kinase MoYck1 in regulating development, autophagy and virulence in M. oryzae [MoYck1]. (Mus musculus) PubMed

 25679.

H-NS clearly appeared as the major repressor of Pef expression. [H-NS; Pef] (Mus musculus) PubMed

 25680.

Acinetobacter trimeric autotransporter adhesin (Ata) is an important multifunctional virulence factor in A. baumannii that mediates adhesion and invasion, induces apoptosis and contributes to pathogenicity in vivo [Ata]. (Mus musculus) PubMed

 25681.

Parallel experimental evolution reveals a novel repressive control of GalP on xylose fermentation in Escherichia coli. (Mus musculus) PubMed

 25682.

Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses. (Mus musculus) PubMed

 25683.

Characterization of the promoter of the nitrate transporter-encoding gene nrtA in Aspergillus nidulans. (Mus musculus) PubMed

 25684.

A regulatory circuit between lncRNA and TOR directs amino acid uptake in yeast. (Mus musculus) PubMed

 25685.

In dek33, a single-base mutation (G to A) in the C-terminal COG3236 domain caused a premature stop codon (TGA), producing a weak mutant allele with only a truncated form of the DEK33 protein that occurred at much lower levels that the completed WT form, and with a reduced riboflavin content. The dek33 mutation significantly affected oil-body formation and suppressed endoreduplication. [Dek33] (Mus musculus) PubMed

 25686.

The AhRLK1 protein was localized in the plasma membrane and cell wall. AhRLK1 was induced in a susceptible variety but little changed in a resistant cultivar after inoculated with Ralstonia solanacearum. Hormones such as salicylic acid, abscisic acid, methyl jasmonate, and ethephon induced AhRLK1 expression. In contrast, AhRLK1 expression was down-regulated under cold and drought treatments. [RLK1] (Mus musculus) PubMed

 25687.

HlyA is a virulence factor that accelerates a state of bacteraemia into fulminant sepsis in a mouse model. (alpha-Haemolysin (HlyA)) (Mus musculus) PubMed

 25688.

Our results are consistent with the idea that the carboxylic acids generated from the oxidation of alcohols are the actual attractants sensed by McfP in P. putida F1, rather than the alcohols themselves [McfP]. (Mus musculus) PubMed

 25689.

We uncovered a feed-forward loop wherein quorum sensing regulators also control transcription of cosR, which encodes a negative regulator of the ect operon [cosR]. (Mus musculus) PubMed

 25690.

This study demonstrates that AcrR regulates the de novo synthesis of fatty acids in L. plantarum adapting to toxic levels of ethanol [AcrR]. (Mus musculus) PubMed

 25691.

EPYC1 interacts with the small subunit of Rubisco (SSU) from Chlamydomonas and that EPYC1 has at least five SSU interaction sites. Interaction is crucially dependent on the two surface-exposed alpha-helices of the Chlamydomonas SSU. EPYC1 could be localized to the chloroplast in higher plants and was not detrimental to growth when expressed stably in Arabidopsis with or without a Chlamydomonas SSU. [EPYC1] (Mus musculus) PubMed

 25692.

PPR-SMR1, a novel splicing factor, acts in the splicing of multiple group II introns in maize mitochondria, and the protein-protein interaction between it and Zm-mCSF1 might allow the formation of large macromolecular splicing complexes. [mCSF1] (Mus musculus) PubMed

 25693.

The study suggests a critical role of zebrafish innate immunity in monitoring invaded pathogens via detecting the bacterial haemolysin-associated outer membrane vesicles and initiating pyroptotic-like cell death. (haemolysin) (Mus musculus) PubMed

 25694.

The secreted M. marinum phosphatases PtpA, PtpB, and SapM determine the mycobacterium-containing vacuole phosphoinositide pattern, compartment acidification, and phagosomal escape. (PtpA, PtpB, and SapM ) (Mus musculus) PubMed

 25695.

This study reports on the development and use of a powerful hydrogen exchange mass spectrometry (HX MS) analysis that can provide positionally resolved information on structure, dynamics, and energetics of the heat shock protein 104 (HSP104) molecular machinery, even during functional cycling.[HSP104] (Mus musculus) PubMed

 25696.

Ternary Complex Formation and Photoactivation of a Photoenzyme Results in Altered Protein Dynamics. (Mus musculus) PubMed

 25697.

MapB, the Brucella suis TamB homologue, is involved in cell envelope biogenesis, cell division and virulence. (Mus musculus) PubMed

 25698.

Chemo-Mechanical Coupling in the Transport Cycle of a Heme ABC Transporter. (Mus musculus) PubMed

 25699.

Probing the pH Effects on Sugar Binding to a Polysaccharide Lyase. (Mus musculus) PubMed

 25700.

Computational Studies of SARS-CoV-2 3CLpro: Insights from MD Simulations. (Mus musculus) PubMed

 25701.

Circular RNA circDLGAP4 exerts neuroprotective effects via modulating miR-134-5p/CREB pathway in Parkinson's disease. (Mus musculus) PubMed

 25702.

Structural transitions in influenza haemagglutinin at membrane fusion pH. (Mus musculus) PubMed

 25703.

OsGL6, a conserved AP2 domain protein, promotes leaf trichome initiation in rice. (Mus musculus) PubMed

 25704.

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation. (Mus musculus) PubMed

 25705.

Comprehensive analysis of variation of cadmium accumulation in rice and detection of a new weak allele of OsHMA3. (Mus musculus) PubMed

 25706.

ABC transporter OsABCG18 controls the shootward transport of cytokinins and grain yield in rice. (Mus musculus) PubMed

 25707.

The protective effects of long non-coding RNA-ANCR on arterial calcification. (Mus musculus) PubMed

 25708.

Decreased accumulation of superoxide dismutase 2 within mitochondria in the yeast model of Shwachman-Diamond syndrome. (Mus musculus) PubMed

 25709.

Mechanism of Phosphatidylglycerol Activation Catalyzed by Prolipoprotein Diacylglyceryl Transferase. (Mus musculus) PubMed

 25710.

Protection from hydrogen peroxide stress relies mainly on AhpCF and KatA2 in Stenotrophomonas maltophilia. (Mus musculus) PubMed

 25711.

Unique features of the grapevine VvK5.1 channel support novel functions for outward K+ channels in plants. (Mus musculus) PubMed

 25712.

Deletion of the Pseudorabies Virus gE/gI-US9p complex disrupts kinesin KIF1A and KIF5C recruitment during egress, and alters the properties of microtubule-dependent transport in vitro. (Mus musculus) PubMed

 25713.

A secreted LysM effector protects fungal hyphae through chitin-dependent homodimer polymerization. (Mus musculus) PubMed

 25714.

Essential roles for deubiquitination in Leishmania life cycle progression. (Mus musculus) PubMed

 25715.

these findings indicate a major role for RNase AM in cellular RNA metabolism and establish a biological role for the first 5' to 3' RNA exonuclease identified in E. coli (RNase AM). (Mus musculus) PubMed

 25716.

Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein (L protein). (Mus musculus) PubMed

 25717.

Identification of FosA8, a Plasmid-Encoded Fosfomycin Resistance Determinant from Escherichia coli, and Its Origin in Leclercia adecarboxylata. (Mus musculus) PubMed

 25718.

Identification of secretion domain of Neospora caninum profilin. (Mus musculus) PubMed

 25719.

A novel bHLH transcription factor, NtbHLH1, modulates iron homeostasis in tobacco (Nicotiana tabacum L.). (Mus musculus) PubMed

 25720.

The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition. (Mus musculus) PubMed

 25721.

RpoS is a pleiotropic regulator of motility, biofilm formation, exoenzymes, siderophore and prodigiosin production, and trade-off during prolonged stationary phase in Serratia marcescens. (Mus musculus) PubMed

 25722.

Structure and mechanism of the Nap adhesion complex from the human pathogen Mycoplasma genitalium. (Mus musculus) PubMed

 25723.

Crystal structure of beta-L-arabinobiosidase belonging to glycoside hydrolase family 121. (Mus musculus) PubMed

 25724.

Analysis of p67 allelic sequences reveals a subtype of allele type 1 unique to buffalo-derived Theileria parva parasites from southern Africa. (Mus musculus) PubMed

 25725.

CdsA is involved in biosynthesis of glycolipid MPIase essential for membrane protein integration in vivo. (Mus musculus) PubMed

 25726.

Two putative zinc metalloproteases contribute to the virulence of Clostridium perfringens strains that cause avian necrotic enteritis. (Mus musculus) PubMed

 25727.

TaHsfA2-1, a new gene for thermotolerance in wheat seedlings: Characterization and functional roles. (Mus musculus) PubMed

 25728.

Crystal structure of rice defensin OsAFP1 and molecular insight into lipid-binding. (Mus musculus) PubMed

 25729.

SbWRKY30 enhances the drought tolerance of plants and regulates a drought stress-responsive gene, SbRD19, in sorghum. (Mus musculus) PubMed

 25730.

Cloning and functional characterization of xylitol dehydrogenase genes from Issatchenkia orientalis and Torulaspora delbrueckii. (Mus musculus) PubMed

 25731.

Cloning and functional characterization of xylitol dehydrogenase genes from Issatchenkia orientalis and Torulaspora delbrueckii. (Mus musculus) PubMed

 25732.

Mutations in sigma 70 transcription factor improves expression of functional eukaryotic membrane proteins in Escherichia coli. (Mus musculus) PubMed

 25733.

High-resolution experimental and computational electrophysiology reveals weak beta-lactam binding events in the porin PorB. (Mus musculus) PubMed

 25734.

EPR Spectroscopy Detects Various Active State Conformations of the Transcriptional Regulator CueR. (Mus musculus) PubMed

 25735.

PINOID Is Required for Formation of the Stigma and Style in Rice. (Mus musculus) PubMed

 25736.

OsPINOID Regulates Stigma and Ovule Initiation through Maintenance of the Floral Meristem by Auxin Signaling. (Mus musculus) PubMed

 25737.

Plasmodium falciparum histidine-rich protein (PfHRP2 and 3) diversity in Western and Coastal Kenya. (Mus musculus) PubMed

 25738.

Characterization and Cloning of Grape Circular RNAs Identified the Cold Resistance-Related Vv-circATS1. (Mus musculus) PubMed

 25739.

Down-regulation of the Sucrose Transporter CsSUT1 Causes Male Sterility by Altering Carbohydrate Supply. (Mus musculus) PubMed

 25740.

The Golgi Localization of GnTI Requires a Polar Amino Acid Residue within Its Transmembrane Domain. (Mus musculus) PubMed

 25741.

Cholix toxin, an eukaryotic elongation factor 2 ADP-ribosyltransferase, interacts with Prohibitins and induces apoptosis with mitochondrial dysfunction in human hepatocytes. (Mus musculus) PubMed

 25742.

Mec1(ATR) Autophosphorylation and Ddc2(ATRIP) Phosphorylation Regulates DNA Damage Checkpoint Signaling. (Mus musculus) PubMed

 25743.

A Critical Role of Sodium Flux via the Plasma Membrane Na(+)/H(+) Exchanger SOS1 in the Salt Tolerance of Rice. (Mus musculus) PubMed

 25744.

Salmonella Coiled-Coil- and TIR-Containing TcpS Evades the Innate Immune System and Subdues Inflammation. (Mus musculus) PubMed

 25745.

Porcine sialoadhesin suppresses type I interferon production to support porcine reproductive and respiratory syndrome virus infection. (Mus musculus) PubMed

 25746.

Herpes Simplex Virus Type 1-Encoded miR-H2-3p Manipulates Cytosolic DNA-Stimulated Antiviral Innate Immune Response by Targeting DDX41. (Mus musculus) PubMed

 25747.

Two Novel Amyloid Proteins, RopA and RopB, from the Root Nodule Bacterium Rhizobium leguminosarum. (Mus musculus) PubMed

 25748.

Indole contributes to tetracycline resistance via the outer membrane protein OmpN in Vibrio splendidus. (Mus musculus) PubMed

 25749.

Proteomics Computational Analyses Suggest that the Antennavirus Glycoprotein Complex Includes a Class I Viral Fusion Protein (alpha-Penetrene) with an Internal Zinc-Binding Domain and a Stable Signal Peptide. (Mus musculus) PubMed

 25750.

A Transcription Factor, OsMADS57, Regulates Long-Distance Nitrate Transport and Root Elongation. (Mus musculus) PubMed

 25751.

The Amino Acid Permease 5 (OsAAP5) Regulates Tiller Number and Grain Yield in Rice. (Mus musculus) PubMed

 25752.

A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation. (Mus musculus) PubMed

 25753.

The Legionella kinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation. (Mus musculus) PubMed

 25754.

Dicer-like 5 deficiency confers temperature-sensitive male sterility in maize. (Mus musculus) PubMed

 25755.

Conserved protein Pir2(ARS2) mediates gene repression through cryptic introns in lncRNAs. (Mus musculus) PubMed

 25756.

ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals. (Mus musculus) PubMed

 25757.

Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. (Mus musculus) PubMed

 25758.

A Toxoplasma gondii patatin-like phospholipase contributes to host cell invasion. (Mus musculus) PubMed

 25759.

Wheat TaSPL8 Modulates Leaf Angle Through Auxin and Brassinosteroid Signaling. (Mus musculus) PubMed

 25760.

Identification of an adaptor protein-2 mu gene (AccAP2m) in Apis cerana cerana and its role in oxidative stress responses. (Mus musculus) PubMed

 25761.

Nej1 Interacts with Mre11 to Regulate Tethering and Dna2 Binding at DNA Double-Strand Breaks. (Mus musculus) PubMed

 25762.

Low-expression of lncRNA-ANCR promotes tibial fracture healing via targeting RUNX2. (Mus musculus) PubMed

 25763.

MiR-27a alleviates osteoarthritis in rabbits via inhibiting inflammation. (Mus musculus) PubMed

 25764.

How many protein molecules are secreted by single Helicobacter pylori cells: Quantification of serine protease HtrA. (Mus musculus) PubMed

 25765.

Further in vivo evidence implying DNA apurinic/apyrimidinic endonuclease activity in Trypanosoma cruzi oxidative stress survival. (Mus musculus) PubMed

 25766.

Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes. (Mus musculus) PubMed

 25767.

The zebrafish NLRP3 inflammasome has functional roles in ASC-dependent interleukin-1beta maturation and gasdermin E-mediated pyroptosis. (Mus musculus) PubMed

 25768.

Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and alpha-Synuclein Proteotoxicity. (Mus musculus) PubMed

 25769.

Syntaxin 5 Is Required for the Formation and Clearance of Protein Inclusions during Proteostatic Stress. (Mus musculus) PubMed

 25770.

Expression of Murine CD80 by Herpes Simplex Virus 1 in Place of Latency-Associated Transcript (LAT) Can Compensate for Latency Reactivation and Anti-apoptotic Functions of LAT. (Mus musculus) PubMed

 25771.

C-Mannosylation of Toxoplasma gondii proteins promotes attachment to host cells and parasite virulence. (Mus musculus) PubMed

 25772.

Phylogenetics, Genomic Recombination, and NSP2 Polymorphic Patterns of Porcine Reproductive and Respiratory Syndrome Virus in China and the United States in 2014-2018. (Mus musculus) PubMed

 25773.

Murine Cytomegalovirus Protein pM49 Interacts with pM95 and Is Critical for Viral Late Gene Expression. (Mus musculus) PubMed

 25774.

The potassium transporter KdpA affects persister formation by regulating ATP levels in Mycobacterium marinum. (Mus musculus) PubMed

 25775.

Loss of Cyp11c1 causes delayed spermatogenesis due to the absence of 11-ketotestosterone. (Mus musculus) PubMed

 25776.

RedH and PigC Catalyze the Biosynthesis of Hybrubins via Phosphorylation of 4'-Methoxy-2,2'-Bipyrrole-5'-Carbaldehyde. (Mus musculus) PubMed

 25777.

Ethylene insensitive3-like2 (OsEIL2) confers stress sensitivity by regulating OsBURP16, the beta subunit of polygalacturonase (PG1beta-like) subfamily gene in rice. (Mus musculus) PubMed

 25778.

A two-pore channel protein required for regulating mTORC1 activity on starvation. (Mus musculus) PubMed

 25779.

Overexpression of PtDefensin enhances resistance to Septotis populiperda in transgenic poplar. (Mus musculus) PubMed

 25780.

Identification of two recessive etiolation genes (py1, py2) in pakchoi (Brassica rapa L. ssp. chinensis). (Mus musculus) PubMed

 25781.

Circular RNA COL1A2 promotes angiogenesis via regulating miR-29b/VEGF axis in diabetic retinopathy. (Mus musculus) PubMed

 25782.

c-di-GMP inhibits LonA-dependent proteolysis of TfoY in Vibrio cholerae. (Mus musculus) PubMed

 25783.

The Whi2p-Psr1p/Psr2p complex regulates interference competition and expansion of cells with competitive advantage in yeast colonies. (Mus musculus) PubMed

 25784.

ZapE/Afg1 interacts with Oxa1 and its depletion causes a multifaceted phenotype. (Mus musculus) PubMed

 25785.

Chloroplast Sec14-like 1 (CPSFL1) is essential for normal chloroplast development and affects carotenoid accumulation in Chlamydomonas. (Mus musculus) PubMed

 25786.

The role of ROC75 as a daytime component of the circadian oscillator in Chlamydomonas reinhardtii. (Mus musculus) PubMed

 25787.

Extracellular loops of BtuB facilitate transport of vitamin B12 through the outer membrane of E. coli. (Mus musculus) PubMed

 25788.

Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase. (Mus musculus) PubMed

 25789.

Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding. (Mus musculus) PubMed

 25790.

The AAA+ protease ClpXP can easily degrade a 31 and a 52-knotted protein. (Mus musculus) PubMed

 25791.

Mutations in Both the Surface and Transmembrane Envelope Glycoproteins of the RAV-2 Subgroup B Avian Sarcoma and Leukosis Virus Are Required to Escape the Antiviral Effect of a Secreted Form of the Tvb(S3) Receptor dagger. (Mus musculus) PubMed

 25792.

Overexpression of SmeGH contributes to the acquired MDR of Stenotrophomonas maltophilia. (Mus musculus) PubMed

 25793.

Involvement of mind the gap in the organization of the tracheal apical extracellular matrix in Drosophila and Nilaparvata lugens. (Mus musculus) PubMed

 25794.

Dynamics of the E. coli beta-Clamp Dimer Interface and Its Influence on DNA Loading. (Mus musculus) PubMed

 25795.

Identification of two clip domain serine proteases involved in the pea aphid's defense against bacterial and fungal infection. (Mus musculus) PubMed

 25796.

Precise genome editing using a CRISPR-Cas9 method highlights the role of CoERG11 amino acid substitutions in azole resistance in Candida orthopsilosis. (Mus musculus) PubMed

 25797.

Chronic CagA-positive Helicobacter pylori infection with MNNG stimulation synergistically induces mesenchymal and cancer stem cell-like properties in gastric mucosal epithelial cells. (Mus musculus) PubMed

 25798.

Aromatic residues surrounding the active site tunnel of TfCel48A influence activity, processivity, and synergistic interactions with other cellulases. (Mus musculus) PubMed

 25799.

Atypical Receptor Kinase RINRK1 Required for Rhizobial Infection But Not Nodule Development in Lotus japonicus. (Mus musculus) PubMed

 25800.

The Rice Actin-Binding Protein RMD Regulates Light-Dependent Shoot Gravitropism. (Mus musculus) PubMed

 25801.

BmSd gene regulates the silkworm wing size by affecting the Hippo pathway. (Mus musculus) PubMed

 25802.

LncRNA HIF1A-AS1 contributes to ventricular remodeling after myocardial ischemia/reperfusion injury by adsorption of microRNA-204 to regulating SOCS2 expression. (Mus musculus) PubMed

 25803.

Long non-coding RNA cardiac hypertrophy-associated regulator governs cardiac hypertrophy via regulating miR-20b and the downstream PTEN/AKT pathway. (Mus musculus) PubMed

 25804.

Deciphering the Allosterically Driven Conformational Ensemble in Tryptophan Synthase Evolution. (Mus musculus) PubMed

 25805.

Rice Homeobox Protein KNAT7 Integrates the Pathways Regulating Cell Expansion and Wall Stiffness. (Mus musculus) PubMed

 25806.

The Chlamydomonas deg1c Mutant Accumulates Proteins Involved in High Light Acclimation. (Mus musculus) PubMed

 25807.

Transcription Factor bHLH2 Represses CYSTEINE PROTEASE77 to Negatively Regulate Nodule Senescence. (Mus musculus) PubMed

 25808.

Isoforms of Acyl-CoA:Diacylglycerol Acyltransferase2 Differ Substantially in Their Specificities toward Erucic Acid. (Mus musculus) PubMed

 25809.

Characterization of the mechanism of thioredoxin-dependent activation of gamma-glutamylcyclotransferase, RipAY, from Ralstonia solanacearum. (Mus musculus) PubMed

 25810.

Rational modulation of the enzymatic intermediates for tuning the phosphatase activity of histidine kinase HK853. (Mus musculus) PubMed

 25811.

Enzymatic synthesis of non-digestible oligosaccharide catalyzed by dextransucrase and dextranase from maltose acceptor reaction. (Mus musculus) PubMed

 25812.

Conformational Plasticity of the Active Site Entrance in E. coli Aspartate Transcarbamoylase and Its Implication in Feedback Regulation. (Mus musculus) PubMed

 25813.

Endo-beta-1,3-glucanase (GH16 Family) from Trichoderma harzianum Participates in Cell Wall Biogenesis but Is Not Essential for Antagonism Against Plant Pathogens. (Mus musculus) PubMed

 25814.

The C-type lectin IML-10 promotes hemocytic encapsulation by enhancing aggregation of hemocytes in the Asian corn borer Ostrinia furnacalis. (Mus musculus) PubMed

 25815.

Detection of a Quinolone Resistance Mutation in gyrA in Escherichia albertii. (Mus musculus) PubMed

 25816.

Characterization of the immune roles of cathepsin L in turbot (Scophthalmus maximus L.) mucosal immunity. (Mus musculus) PubMed

 25817.

Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd. (Mus musculus) PubMed

 25818.

The DEAD-box RNA helicase CshA is required for fatty acid homeostasis in Staphylococcus aureus. (Mus musculus) PubMed

 25819.

Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. (Mus musculus) PubMed

 25820.

Molecular architecture and activation of the insecticidal protein Vip3Aa from Bacillus thuringiensis. (Mus musculus) PubMed

 25821.

CRL4Cdt2 ubiquitin ligase regulates Dna2 and Rad16 (XPF) nucleases by targeting Pxd1 for degradation. (Mus musculus) PubMed

 25822.

LncRNA-Safe contributes to cardiac fibrosis through Safe-Sfrp2-HuR complex in mouse myocardial infarction. (Mus musculus) PubMed

 25823.

Unfolding of CBP21, a lytic polysaccharide monooxygenase, without dissociation of its copper ion cofactor. (Mus musculus) PubMed

 25824.

The peptide-encoding MtRGF3 gene negatively regulates nodulation of Medicago truncatula. (Mus musculus) PubMed

 25825.

GATAe transcription factor is involved in Bacillus thuringiensis Cry1Ac toxin receptor gene expression inducing toxin susceptibility. (Mus musculus) PubMed

 25826.

GATA-type transcriptional factor Gat1 regulates nitrogen uptake and polymalic acid biosynthesis in polyextremotolerant fungus Aureobasidium pullulans. (Mus musculus) PubMed

 25827.

MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis. (Mus musculus) PubMed

 25828.

PvrA is a novel regulator that contributes to Pseudomonas aeruginosa pathogenesis by controlling bacterial utilization of long chain fatty acids. (Mus musculus) PubMed

 25829.

Deacetylation enhances ParB-DNA interactions affecting chromosome segregation in Streptomyces coelicolor. (Mus musculus) PubMed

 25830.

Structural basis of the XPB-Bax1 complex as a dynamic helicase-nuclease machinery for DNA repair. (Mus musculus) PubMed

 25831.

Structural basis of the XPB-Bax1 complex as a dynamic helicase-nuclease machinery for DNA repair. (Mus musculus) PubMed

 25832.

DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs. (Mus musculus) PubMed

 25833.

Toxoplasma gondii metacaspase 2 is an important factor that influences bradyzoite formation in the Pru strain. (Mus musculus) PubMed

 25834.

TaTLP1 interacts with TaPR1 to contribute to wheat defense responses to leaf rust fungus. (Mus musculus) PubMed

 25835.

Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis. (Mus musculus) PubMed

 25836.

A homopolymeric adenosine tract in the promoter region of nspA influences factor H-mediated serum resistance in Neisseria meningitidis. (Mus musculus) PubMed

 25837.

A role for Vibrio vulnificus PecS during hypoxia. (Mus musculus) PubMed

 25838.

Functional analysis of ZmMADS1a reveals its role in regulating starch biosynthesis in maize endosperm. (Mus musculus) PubMed

 25839.

LncRNA Erbb4-IR promotes esophageal squamous cell carcinoma (ESCC) by downregulating miR-145. (Mus musculus) PubMed

 25840.

Staphylococcal phosphatidylinositol-specific phospholipase C potentiates lung injury via complement sensitisation. (Mus musculus) PubMed

 25841.

The LAMMER kinase is involved in morphogenesis and response to cell wall- and DNA-damaging stresses in Candida albicans. (Mus musculus) PubMed

 25842.

Novel regulatory roles of PtdIns(4,5)P2 generating enzyme EhPIPKI in actin dynamics and phagocytosis of Entamoeba histolytica. (Mus musculus) PubMed

 25843.

A new host cell internalisation pathway for SadA-expressing staphylococci triggered by excreted neurochemicals. (Mus musculus) PubMed

 25844.

The histone acetyltransferase GcnE regulates conidiation and biofilm formation in Aspergillus fumigatus. (Mus musculus) PubMed

 25845.

CrpP, a passenger or a hidden stowaway in the Pseudomonas aeruginosa genome? (Mus musculus) PubMed

 25846.

Polymyxin resistance in Klebsiella pneumoniae: multifaceted mechanisms utilized in the presence and absence of the plasmid-encoded phosphoethanolamine transferase gene mcr-1. (Mus musculus) PubMed

 25847.

EhRabB mobilises the EhCPADH complex through the actin cytoskeleton during phagocytosis of Entamoeba histolytica. (Mus musculus) PubMed

 25848.

A crucial role for the C-terminal domain of exported protein 1 during the mosquito and hepatic stages of the Plasmodium berghei life cycle. (Mus musculus) PubMed

 25849.

A single amino acid substitution (H451Y) in Leishmania calcium-dependent kinase SCAMK confers high tolerance and resistance to antimony. (Mus musculus) PubMed

 25850.

Melanoma-derived exosomes induce reprogramming fibroblasts into cancer-associated fibroblasts via Gm26809 delivery. (Mus musculus) PubMed

 25851.

Down-regulated lncRNA TP73-AS1 reduces radioresistance in hepatocellular carcinoma via the PTEN/Akt signaling pathway. (Mus musculus) PubMed

 25852.

Characterizing the PRRSV nsp2 Deubiquitinase Reveals Dispensability of Cis-Activity for Replication and a Link of nsp2 to Inflammation Induction. (Mus musculus) PubMed

 25853.

The Transcriptional Regulator HbxA Governs Development, Secondary Metabolism, and Virulence in Aspergillus fumigatus. (Mus musculus) PubMed

 25854.

Kinetic and structural analysis of Escherichia coli phosphoenolpyruvate carboxykinase mutants. (Mus musculus) PubMed

 25855.

Stochastic Expression of Sae-Dependent Virulence Genes during Staphylococcus aureus Biofilm Development Is Dependent on SaeS. (Mus musculus) PubMed

 25856.

Genetic Determinants of Altered Virulence of Type O Foot-and-Mouth Disease Virus. (Mus musculus) PubMed

 25857.

The Tip of the VgrG Spike Is Essential to Functional Type VI Secretion System Assembly in Acinetobacter baumannii. (Mus musculus) PubMed

 25858.

Immune exclusion by naturally acquired secretory IgA against pneumococcal pilus-1. (Mus musculus) PubMed

 25859.

Zika Virus Non-Structural Protein NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon. (Mus musculus) PubMed

 25860.

Fine-mapping of a major QTL (Fwr1) for fusarium wilt resistance in radish. (Mus musculus) PubMed

 25861.

HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling. (Mus musculus) PubMed

 25862.

Modulation of innate immune signaling by a Coxiella burnetii eukaryotic-like effector protein. (Mus musculus) PubMed

 25863.

Insights into the thermostability and product specificity of a maltooligosaccharide-forming amylase from Bacillus stearothermophilus STB04. (Mus musculus) PubMed

 25864.

miR477 targets the phenylalanine ammonia-lyase gene and enhances the susceptibility of the tea plant (Camellia sinensis) to disease during Pseudopestalotiopsis species infection. (Mus musculus) PubMed

 25865.

Structure of the essential inner membrane lipopolysaccharide-PbgA complex. (Mus musculus) PubMed

 25866.

Expression of tachykinin3 and related reproductive markers in the brain of the African cichlid fish Astatotilapia burtoni. (Mus musculus) PubMed

 25867.

SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70. (Mus musculus) PubMed

 25868.

Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21. (Mus musculus) PubMed

 25869.

A novel plasmid-mediated polymyxin resistance determinant (mcr-1.8) in Escherichia coli recovered from broiler chickens in Brunei Darussalam. (Mus musculus) PubMed

 25870.

An unexpected second binding site for polypeptide substrates is essential for Hsp70 chaperone activity. (Mus musculus) PubMed

 25871.

Glutamate dehydrogenase mediated amino acid metabolism after ammonium uptake enhances rice growth under aeration condition. (Mus musculus) PubMed

 25872.

KIN-4/MAST kinase promotes PTEN-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain. (Mus musculus) PubMed

 25873.

Single-residue physicochemical characteristics kinetically partition membrane protein self-assembly and aggregation. (Mus musculus) PubMed

 25874.

Structural basis of the binding affinity of chemoreceptors Mlp24p and Mlp37p for various amino acids. (Mus musculus) PubMed

 25875.

Transmembrane helix 6b links proton and metal release pathways and drives conformational change in an Nramp-family transition metal transporter. (Mus musculus) PubMed

 25876.

Pathogenicity and immunogenicity of a new strain of porcine epidemic diarrhea virus containing a novel deletion in the N gene. (Mus musculus) PubMed

 25877.

The Tolerance of Salinity in Rice Requires the Presence of a Functional Copy of FLN2. (Mus musculus) PubMed

 25878.

The putative bacterial oxygen sensor Pseudomonas prolyl hydroxylase (PPHD) suppresses antibiotic resistance and pathogenicity in Pseudomonas aeruginosa. (Mus musculus) PubMed

 25879.

A novel maize dwarf mutant generated by Ty1-copia LTR-retrotransposon insertion in Brachytic2 after spaceflight. (Mus musculus) PubMed

 25880.

Characterization of the Riemerella anatipestifer M949_RS00050 gene. (Mus musculus) PubMed

 25881.

RADICLELESS 1 (RL1)-mediated nad4 intron 1 splicing is crucial for embryo and endosperm development in rice (Oryza sativa L.). (Mus musculus) PubMed

 25882.

Cytokinin oxidase PpCKX1 plays regulatory roles in development and enhances dehydration and salt tolerance in Physcomitrella patens. (Mus musculus) PubMed

 25883.

Cell apoptosis regulated by interaction between viral gene alpha 3 and host heterogeneous nuclear ribonucleoprotein K facilitates bovine ephemeral fever virus replication. (Mus musculus) PubMed

 25884.

A family of hyperpolarization-activated channels selective for protons. (Mus musculus) PubMed

 25885.

Complete Stereoinversion of l-Tryptophan by a Fungal Single-Module Nonribosomal Peptide Synthetase. (Mus musculus) PubMed

 25886.

A DEAD-box RNA helicase TCD33 that confers chloroplast development in rice at seedling stage under cold stress. (Mus musculus) PubMed

 25887.

African horse sickness virus NS4 is a nucleocytoplasmic protein that localizes to PML nuclear bodies. (Mus musculus) PubMed

 25888.

An EMS-induced mutation in a tetratricopeptide repeat-like superfamily protein gene (Ghir_A12G008870) on chromosome A12 is responsible for the liy short fiber phenotype in cotton. (Mus musculus) PubMed

 25889.

crystal structure of a TMEM16 family member from the fungus Nectria haematococca that operates as a Ca(2+)-activated lipid scramblase [TMEM16] (Mus musculus) PubMed

 25890.

Using molecular dynamics simulations coupled with experimental assays, the authors show that the surface hydrophilic transmembrane cavity exposed to the lipid bilayer on the fungal scramblase nhTMEM16 serves as the pathway for both lipid translocation and ion conduction across the membrane.[TMEM16] (Mus musculus) PubMed

 25891.

The cytoplasmic portion of TMEM16 is important for function, it does not appear to regulate scramblase activity via a detectable conformational change. [TMEM16] (Mus musculus) PubMed

 25892.

The crystal structure of the chitinase ChiA74 of Bacillus thuringiensis has a multidomain assembly. (Mus musculus) PubMed

 25893.

The Cdc48-20S proteasome degrades a class of endogenous proteins in a ubiquitin-independent manner. (Mus musculus) PubMed

 25894.

Mitochondrial localization of Dictyostelium discoideum dUTPase mediated by its N-terminus. (Mus musculus) PubMed

 25895.

Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites. (Mus musculus) PubMed

 25896.

Effects of the Q80K Polymorphism on the Physicochemical Properties of Hepatitis C Virus Subtype 1a NS3 Protease. (Mus musculus) PubMed

 25897.

Structural characterization of the Pseudomonas aeruginosa dehydrogenase AtuB involved in citronellol and geraniol catabolism. (Mus musculus) PubMed

 25898.

Ceramide synthase 2 knockdown suppresses trophozoite growth, migration, in vitro encystment and excystment of Entamoeba invadens. (Mus musculus) PubMed

 25899.

PCNA Deubiquitylases Control DNA Damage Bypass at Replication Forks. (Mus musculus) PubMed

 25900.

Single-Molecule Observation of Ligand Binding and Conformational Changes in FeuA. (Mus musculus) PubMed

 25901.

Mutations in reverse transcriptase region of HBV affect Hepatitis B surface antigen titers and its correlation with HBV DNA. (Mus musculus) PubMed

 25902.

QSAR studies on hepatitis C virus NS5A protein tetracyclic inhibitors in wild type and mutants by CoMFA and CoMSIA. (Mus musculus) PubMed

 25903.

The extracellular thioredoxin Etrx3 is required for macrophage infection in Rhodococcus equi. (Mus musculus) PubMed

 25904.

Design of a basigin-mimicking inhibitor targeting the malaria invasion protein RH5. (Mus musculus) PubMed

 25905.

Characterization and heterologous expression of three DGATs from oil palm (Elaeis guineensis) mesocarp in Saccharomyces cerevisiae. (Mus musculus) PubMed

 25906.

Chlamydomonas cell cycle mutant crcdc5 over-accumulates starch and oil. (Mus musculus) PubMed

 25907.

Overexpression of Banana ATG8f Modulates Drought Stress Resistance in Arabidopsis. (Mus musculus) PubMed

 25908.

Silencing Leukocyte Immunoglobulin-Like Receptor A1 in Monocytes Inhibits Inflammation in Mice with Multiple Sclerosis. (Mus musculus) PubMed

 25909.

Regulatory network of two circRNAs and an miRNA with their targeted genes under astilbin treatment in pulmonary fibrosis. (Mus musculus) PubMed

 25910.

Novel blaCTX-M variants and genotype-phenotype correlations among clinical isolates of extended spectrum beta lactamase-producing Escherichia coli. (Mus musculus) PubMed

 25911.

The Gly152Val mutation possibly confers resistance to beta-lactam antibiotics in ovine Staphylococcus aureus isolates. (Mus musculus) PubMed

 25912.

Cardiac Contractility Modulation Attenuates Chronic Heart Failure in a Rabbit Model via the PI3K/AKT Pathway. (Mus musculus) PubMed

 25913.

Disome and Trisome Profiling Reveal Genome-wide Targets of Ribosome Quality Control. (Mus musculus) PubMed

 25914.

Functional analysis of the OsNPF4.5 nitrate transporter reveals a conserved mycorrhizal pathway of nitrogen acquisition in plants. (Mus musculus) PubMed

 25915.

Enzymatic Characteristics of a Polyphosphate/ATP-NAD Kinase, PanK, from Myxococcus xanthus. (Mus musculus) PubMed

 25916.

Identification of Lysine Acetylation Sites on MERS-CoV Replicase pp1ab. (Mus musculus) PubMed

 25917.

Circadian clock mechanism driving mammalian photoperiodism. (Mus musculus) PubMed

 25918.

Bulk and single-molecule analysis of a bacterial DNA2-like helicase-nuclease reveals a single-stranded DNA looping motor. (Mus musculus) PubMed

 25919.

An orphan protein of Fusarium graminearum modulates host immunity by mediating proteasomal degradation of TaSnRK1alpha. (Mus musculus) PubMed

 25920.

The identified the chaperone activity of the HtrA protein and have proven that this activity is important and sufficient for the survival of H. pylori under multiple stress conditions.(HtrA) (Mus musculus) PubMed

 25921.

Details of hydrophobic entanglement between small molecules and Braun's lipoprotein within the cavity of the bacterial chaperone LolA. (Mus musculus) PubMed

 25922.

The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers. (Mus musculus) PubMed

 25923.

MhpA Is a Hydroxylase Catalyzing the Initial Reaction of 3-(3-Hydroxyphenyl)Propionate Catabolism in Escherichia coli K-12. (Mus musculus) PubMed

 25924.

Glyoxylate cycle gene ICL1 is essential for the metabolic flexibility and virulence of Candida glabrata. (Mus musculus) PubMed

 25925.

Anopheline antiplatelet protein from mosquito saliva regulates blood feeding behavior. (Mus musculus) PubMed

 25926.

Long non-coding RNA LOC285194 regulates vascular smooth muscle cell apoptosis in atherosclerosis. (Mus musculus) PubMed

 25927.

A novel bovine CXCL15 gene in the GRO chemokine gene cluster. (Mus musculus) PubMed

 25928.

The pentaglycine bridges of Staphylococcus aureus peptidoglycan are essential for cell integrity. (Mus musculus) PubMed

 25929.

A Novel d-Allulose 3-Epimerase Gene from the Metagenome of a Thermal Aquatic Habitat and d-Allulose Production by Bacillus subtilis Whole-Cell Catalysis. (Mus musculus) PubMed

 25930.

Comparative evaluation of structure and characteristic of peptidyl-prolyl cis-trans isomerase proteins and their function in Salmonella Typhimurium stress responses and virulence. (Mus musculus) PubMed

 25931.

Teleost IgD(+)IgM(-) B Cells Mount Clonally Expanded and Mildly Mutated Intestinal IgD Responses in the Absence of Lymphoid Follicles. (Mus musculus) PubMed

 25932.

OxyR-controlled surface polysaccharide production and biofilm formation in Acinetobacter oleivorans DR1. (Mus musculus) PubMed

 25933.

TRAF3 enhances TRIF-mediated signaling via NF-kappaB and IRF3 activation in large yellow croaker Larimichthys crocea. (Mus musculus) PubMed

 25934.

IgG immune complexes with Staphylococcus aureus protein A enhance osteoclast differentiation and bone resorption by stimulating Fc receptors and TLR2. (Mus musculus) PubMed

 25935.

Characterization and application of a gall midge resistance gene (Gm6) from Oryza sativa 'Kangwenqingzhan'. (Mus musculus) PubMed

 25936.

Localized Electronic Structure of Nitrogenase FeMoco Revealed by Selenium K-Edge High Resolution X-ray Absorption Spectroscopy. (Mus musculus) PubMed

 25937.

Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. (Mus musculus) PubMed

 25938.

Genomic organization of the chicken TCRbeta locus originated by duplication of a Vbeta segment combined with a trypsinogen gene. (Mus musculus) PubMed

 25939.

A heat-sensitive Osh protein controls PI4P polarity. (Mus musculus) PubMed

 25940.

Gp4 is a nuclease required for morphogenesis of T4-like bacteriophages. (Mus musculus) PubMed

 25941.

Hyper-phosphorylation of nsp2-related proteins of porcine reproductive and respiratory syndrome virus. (Mus musculus) PubMed

 25942.

Trapping of a Putative Intermediate in the Cytochrome c Nitrite Reductase (ccNiR)-Catalyzed Reduction of Nitrite: Implications for the ccNiR Reaction Mechanism. (Mus musculus) PubMed

 25943.

Gb8, a new gene conferring resistance to economically important greenbug biotypes in wheat. (Mus musculus) PubMed

 25944.

MftD Catalyzes the Formation of a Biologically Active Redox Center in the Biosynthesis of the Ribosomally Synthesized and Post-translationally Modified Redox Cofactor Mycofactocin. (Mus musculus) PubMed

 25945.

Identification of a novel type I pullulanase from Fervidobacterium nodosum Rt17-B1, with high thermostability and suitable optimal pH. (Mus musculus) PubMed

 25946.

Molecular and structural analysis of a mechanical transition of helices in the L. donovani coronin coiled-coil domain. (Mus musculus) PubMed

 25947.

ABA-dependent bZIP transcription factor, CsbZIP18, from Camellia sinensis negatively regulates freezing tolerance in Arabidopsis. (Mus musculus) PubMed

 25948.

Rad53 limits CMG helicase uncoupling from DNA synthesis at replication forks. (Mus musculus) PubMed

 25949.

Glutamine synthetase type I (glnAI) represents a rewarding molecular marker in the classification of bifidobacteria and related genera. (Mus musculus) PubMed

 25950.

E3 Ligase ITCH Interacts with the Z Matrix Protein of Lassa and Mopeia Viruses and Is Required for the Release of Infectious Particles. (Mus musculus) PubMed

 25951.

Mouse Cytomegalovirus Differentially Exploits Cell Surface Glycosaminoglycans in a Cell Type-Dependent and MCK-2-Independent Manner. (Mus musculus) PubMed

 25952.

The overexpression of OsSRO1a, which encodes an OsNINJA1- and OsMYC2-interacting protein, negatively affects OsMYC2-mediated jasmonate signaling in rice. (Mus musculus) PubMed

 25953.

BCL-xL, a Mitochondrial Protein Involved in Successful Aging: From C. elegans to Human Centenarians. (Mus musculus) PubMed

 25954.

A putative mechanism underlying secondary metabolite overproduction by Streptomyces strains with a 23S rRNA mutation conferring erythromycin resistance. (Mus musculus) PubMed

 25955.

Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca(2+) -dependent ribonuclease. (Mus musculus) PubMed

 25956.

APETALA 2 transcription factor CBX1 is a regulator of mycorrhizal symbiosis and growth of Lotus japonicus. (Mus musculus) PubMed

 25957.

A tandem GGDEF-EAL domain protein-regulated c-di-GMP signal contributes to spoilage-related activities of Shewanella baltica OS155. (Mus musculus) PubMed

 25958.

Low-Cost Cellulase-Hemicellulase Mixture Secreted by Trichoderma harzianum EM0925 with Complete Saccharification Efficacy of Lignocellulose. (Mus musculus) PubMed

 25959.

Genome-wide transcriptional response of papain-like cysteine protease-mediated resistance against Xanthomonas oryzae pv. oryzae in rice. (Mus musculus) PubMed

 25960.

The velvet Regulator VosA Governs Survival and Secondary Metabolism of Sexual Spores in Aspergillus nidulans. (Mus musculus) PubMed

 25961.

Positive Feedback Loop LINC00511/miR-150-5p/SP1 Modulates Chondrocyte Apoptosis and Proliferation in Osteoarthritis. (Mus musculus) PubMed

 25962.

Structure of a nascent membrane protein as it folds on the BAM complex. (Mus musculus) PubMed

 25963.

The S2 Subunit of QX-type Infectious Bronchitis Coronavirus Spike Protein Is an Essential Determinant of Neurotropism. (Mus musculus) PubMed

 25964.

The oligomeric structures of plant cryptochromes. (Mus musculus) PubMed

 25965.

Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex. (Mus musculus) PubMed

 25966.

Rice OVATE family protein 6 regulates leaf angle by modulating secondary cell wall biosynthesis. (Mus musculus) PubMed

 25967.

A UPR-Induced Soluble ER-Phagy Receptor Acts with VAPs to Confer ER Stress Resistance. (Mus musculus) PubMed

 25968.

Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet. (Mus musculus) PubMed

 25969.

Involvement of the RND efflux pump transporter SmeH in the acquisition of resistance to ceftazidime in Stenotrophomonas maltophilia. (Mus musculus) PubMed

 25970.

Lung myofibroblast transition and fibrosis is regulated by circ0044226. (Mus musculus) PubMed

 25971.

Characterization the role of GacA-dependent small RNAs and RsmA family proteins on 2,4-diacetylphloroglucinol production in Pseudomonas fluorescens 2P24. (Mus musculus) PubMed

 25972.

Identification and characterization of a Masculinizer homologue in the diamondback moth, Plutella xylostella. (Mus musculus) PubMed

 25973.

Functional characterization of the cis-regulatory region for the vitellogenin gene in Plutella xylostella. (Mus musculus) PubMed

 25974.

A novel hepatic lectin of zebrafish Danio rerio is involved in innate immune defense. (Mus musculus) PubMed

 25975.

QM/MM investigation of substrate binding of subclass B3 metallo-beta-lactamase SMB-1 from Serratia marcescents: insights into catalytic mechanism. (Mus musculus) PubMed

 25976.

Citrate synthase from Synechocystis is a distinct class of bacterial citrate synthase. (Mus musculus) PubMed

 25977.

Heterogeneous expression of the ammonium transporter AgAmt in chemosensory appendages of the malaria vector, Anopheles gambiae. (Mus musculus) PubMed

 25978.

In Vivo Cross-Linking MS Reveals Conservation in OmpA Linkage to Different Classes of beta-Lactamase Enzymes. (Mus musculus) PubMed

 25979.

Dengue virus reduces expression of low-density lipoprotein receptor-related protein 1 to facilitate replication in Aedes aegypti. (Mus musculus) PubMed

 25980.

Methods for the generation of heritable germline mutations in the disease vector Culex quinquefasciatus using clustered regularly interspaced short palindrome repeats-associated protein 9. (Mus musculus) PubMed

 25981.

P-S6K is associated with insect diapause via the ROS/AKT/ S6K/CREB/HIF-1 pathway in the cotton bollworm, Helicoverpa armigera. (Mus musculus) PubMed

 25982.

Integration Host Factor IHF facilitates homologous recombination and mutagenic processes in Pseudomonas putida. (Mus musculus) PubMed

 25983.

UvrA and UvrC subunits of the Mycobacterium tuberculosis UvrABC excinuclease interact independently of UvrB and DNA. (Mus musculus) PubMed

 25984.

Transcriptional regulation of heat shock protein 70 genes by class I histone deacetylases in the red flour beetle, Tribolium castaneum. (Mus musculus) PubMed

 25985.

Structural basis for selectivity in a highly reducing type II polyketide synthase. (Mus musculus) PubMed

 25986.

Genomic characterization of a Klebsiella pneumoniae ST1519 resistant to ceftazidime/avibactam carrying a novel KPC variant (KPC-36). (Mus musculus) PubMed

 25987.

High-yield expression of extracellular lipase from Yarrowia lipolytica and its interactions with lipopeptide biosurfactants: A biophysical approach. (Mus musculus) PubMed

 25988.

Vanillin Production in Pseudomonas: Whole-Genome Sequencing of Pseudomonas sp. Strain 9.1 and Reannotation of Pseudomonas putida CalA as a Vanillin Reductase. (Mus musculus) PubMed

 25989.

Direct Electron Transfer between the frhAGB-Encoded Hydrogenase and Thioredoxin Reductase in the Nonmethanogenic Archaeon Thermococcus onnurineus NA1. (Mus musculus) PubMed

 25990.

Functions of duplicated glucosinolate sulfatases in the development and host adaptation of Plutella xylostella. (Mus musculus) PubMed

 25991.

Cefoperazone induces esterase B expression by EstR and esterase B enhances cefoperazone activity at the periplasm. (Mus musculus) PubMed

 25992.

Ubiquitin-Like protein 5 interacts with the silencing suppressor p3 of rice stripe virus and mediates its degradation through the 26S proteasome pathway. (Mus musculus) PubMed

 25993.

Overlapping and distinct roles of CDPK family members in the pre-erythrocytic stages of the rodent malaria parasite, Plasmodium berghei. (Mus musculus) PubMed

 25994.

The orphan histidine kinase PdtaS-p regulates both morphological differentiation and antibiotic biosynthesis together with the orphan response regulator PdtaR-p in Streptomyces. (Mus musculus) PubMed

 25995.

The EngCP endo alpha-N-acetylgalactosaminidase is a virulence factor involved in Clostridium perfringens gas gangrene infections. (Mus musculus) PubMed

 25996.

Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein. (Mus musculus) PubMed

 25997.

A critical regulator of Bcl2 revealed by systematic transcript discovery of lncRNAs associated with T-cell differentiation. (Mus musculus) PubMed

 25998.

Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components. (Mus musculus) PubMed

 25999.

A bacterial display system for effective selection of protein-biotin ligase BirA variants with novel peptide specificity. (Mus musculus) PubMed

 26000.

Prevalence of baseline NS3 resistance-associated substitutions (RASs) on treatment with protease inhibitors in patients infected with HCV genotype 1. (Mus musculus) PubMed

 26001.

Methylcitrate cycle gene MCD is essential for the virulence of Talaromyces marneffei. (Mus musculus) PubMed

 26002.

CteG is a Chlamydia trachomatis effector protein that associates with the Golgi complex of infected host cells. (Mus musculus) PubMed

 26003.

Streptococcus pyogenes nuclease A (SpnA) mediated virulence does not exclusively depend on nuclease activity. (Mus musculus) PubMed

 26004.

Hepatitis C virus sequence divergence preserves p7 viroporin structural and dynamic features. (Mus musculus) PubMed

 26005.

The complex structure of bile salt hydrolase from Lactobacillus salivarius reveals the structural basis of substrate specificity. (Mus musculus) PubMed

 26006.

Advances in the role of HCV nonstructural protein 5a (NS5A) of 3a genotype in inducing insulin resistance by possible phosphorylation of AKT/PKB. (Mus musculus) PubMed

 26007.

Transcriptional activation by MafR, a global regulator of Enterococcus faecalis. (Mus musculus) PubMed

 26008.

The yeast scavenger decapping enzyme DcpS and its application for in vitro RNA recapping. (Mus musculus) PubMed

 26009.

Rif1 promotes association of G-quadruplex (G4) by its specific G4 binding and oligomerization activities. (Mus musculus) PubMed

 26010.

The Staphylococcus aureus ArlRS two-component system regulates virulence factor expression through MgrA. (Mus musculus) PubMed

 26011.

Coordinate regulation of virulence and metabolic genes by the transcription factor HbhR in Mycobacterium marinum. (Mus musculus) PubMed

 26012.

Regulation of Lnc-NTF3-5 on islet beta-cell dysfunction in high glucose environment and related mechanisms. (Mus musculus) PubMed

 26013.

The human protein haptoglobin inhibits IsdH-mediated heme-sequestering by Staphylococcus aureus. (Mus musculus) PubMed

 26014.

Cytological and genetic consequences for the progeny of a mitotic catastrophe provoked by Topoisomerase II deficiency. (Mus musculus) PubMed

 26015.

Heterogeneous expression of Pil3 pilus is critical for Streptococcus gallolyticus translocation across polarized colonic epithelial monolayers. (Mus musculus) PubMed

 26016.

Image mean square displacement to study the lateral mobility of Angiotensin II type 1 and Endothelin 1 type A receptors on living cells. (Mus musculus) PubMed

 26017.

Outer membrane protein A (OmpA) of extraintestinal pathogenic Escherichia coli. (Mus musculus) PubMed

 26018.

Sml1 Inhibits the DNA Repair Activity of Rev1 in Saccharomyces cerevisiae during Oxidative Stress. (Mus musculus) PubMed

 26019.

Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. (Mus musculus) PubMed

 26020.

Unraveling the role of the CbrA histidine kinase in the signal transduction of the CbrAB two-component system in Pseudomonas putida. (Mus musculus) PubMed

 26021.

Female-specific gene regulation in malaria parasites by an AP2-family transcription factor. (Mus musculus) PubMed

 26022.

Prevention of EloR/KhpA heterodimerization by introduction of site-specific amino acid substitutions renders the essential elongasome protein PBP2b redundant in Streptococcus pneumoniae. (Mus musculus) PubMed

 26023.

Crystal structure of the N-terminal domain of the trypanosome flagellar protein BILBO1 reveals a ubiquitin fold with a long structured loop for protein binding. (Mus musculus) PubMed

 26024.

A universal stress protein in Mycobacterium smegmatis sequesters the cAMP-regulated lysine acyltransferase and is essential for biofilm formation. (Mus musculus) PubMed

 26025.

Presence of ES1 homolog in the mitochondrial intermembrane space of porcine retinal cells. (Mus musculus) PubMed

 26026.

The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of Helicobacter pylori in Neutrophils. (Mus musculus) PubMed

 26027.

Evolution for improved secretion and fitness may be the selective pressures leading to the emergence of two NDM alleles. (Mus musculus) PubMed

 26028.

Cryo-EM reveals the architecture of the dimeric cytochrome P450 CYP102A1 enzyme and conformational changes required for redox partner recognition. (Mus musculus) PubMed

 26029.

Deciphering the Rules Underlying Xenogeneic Silencing and Counter-Silencing of Lsr2-like Proteins Using CgpS of Corynebacterium glutamicum as a Model. (Mus musculus) PubMed

 26030.

EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 System. (Mus musculus) PubMed

 26031.

PP2A promotes ESCRT-0 complex formation on vacuolar membranes and microautophagy induction after TORC1 inactivation. (Mus musculus) PubMed

 26032.

DNA topoisomerase IIIbeta promotes cyst generation by inducing cyst wall protein gene expression in Giardia lamblia. (Mus musculus) PubMed

 26033.

EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 System. (Mus musculus) PubMed

 26034.

Lysis of a Lactococcus lactis Dipeptidase Mutant and Rescue by Mutation in the Pleiotropic Regulator CodY. (Mus musculus) PubMed

 26035.

Ferrous-Iron-Activated Transcriptional Factor AdhR Regulates Redox Homeostasis in Clostridium beijerinckii. (Mus musculus) PubMed

 26036.

EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 System. (Mus musculus) PubMed

 26037.

Both ADP-Ribosyl-Binding and Hydrolase Activities of the Alphavirus nsP3 Macrodomain Affect Neurovirulence in Mice. (Mus musculus) PubMed

 26038.

Identification of Genes Required for Glucan Exopolysaccharide Production in Lactobacillus johnsonii Suggests a Novel Biosynthesis Mechanism. (Mus musculus) PubMed

 26039.

PII Signal Transduction Protein GlnK Alleviates Feedback Inhibition of N-Acetyl-l-Glutamate Kinase by l-Arginine in Corynebacterium glutamicum. (Mus musculus) PubMed

 26040.

Molecular Determinants of Substrate Selectivity of a Pneumococcal Rgg-Regulated Peptidase-Containing ABC Transporter. (Mus musculus) PubMed

 26041.

A Disulfide Oxidoreductase (CHU_1165) Is Essential for Cellulose Degradation by Affecting Outer Membrane Proteins in Cytophaga hutchinsonii. (Mus musculus) PubMed

 26042.

Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion. (Mus musculus) PubMed

 26043.

Structure of an Inner Membrane Protein Required for PhoPQ-Regulated Increases in Outer Membrane Cardiolipin. (Mus musculus) PubMed

 26044.

Complement C3aR/C5aR-binding protein Suilysin of Streptococcus suis contributes to monocyte chemotaxis. (Mus musculus) PubMed

 26045.

FgHtf1 Regulates Global Gene Expression towards Aerial Mycelium and Conidiophore Formation in the Cereal Fungal Pathogen Fusarium graminearum. (Mus musculus) PubMed

 26046.

Streptococcus pneumoniae aminopeptidase N contributes to bacterial virulence and elicits a strong innate immune response through MAPK and PI3K/AKT signaling. (Mus musculus) PubMed

 26047.

Caldicellulosiruptor bescii Adheres to Polysaccharides via a Type IV Pilin-Dependent Mechanism. (Mus musculus) PubMed

 26048.

head-bent resistant Hsc70 variants show reduced Hsp40 affinity and altered protein folding activity. (Mus musculus) PubMed

 26049.

Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations. (Mus musculus) PubMed

 26050.

The lipid-dependent structure and function of LacY can be recapitulated and analyzed in phospholipid-containing detergent micelles. (Mus musculus) PubMed

 26051.

Thermosensitive pilus production by FCT type 3 Streptococcus pyogenes controlled by Nra regulator translational efficiency. (Mus musculus) PubMed

 26052.

Exploring the sequence variability of polymerization-involved residues in the production of levan- and inulin-type fructooligosaccharides with a levansucrase. (Mus musculus) PubMed

 26053.

The regulation of the sulfur amino acid biosynthetic pathway in Cryptococcus neoformans: the relationship of Cys3, Calcineurin, and Gpp2 phosphatases. (Mus musculus) PubMed

 26054.

ZEB and Snail expression indicates epithelial-mesenchymal transition in canine melanoma. (Mus musculus) PubMed

 26055.

The KdpD/KdpE two-component system contributes to the motility and virulence of avian pathogenic Escherichia coli. (Mus musculus) PubMed

 26056.

Construction expression and immunogenicity of a novel trivalent outer membrane protein (OmpU-A-II) from three bacterial pathogens in Japanese eels (Anguilla japonica). (Mus musculus) PubMed

 26057.

Second messengers and divergent HD-GYP phosphodiesterases regulate 3',3'-cGAMP signaling. (Mus musculus) PubMed

 26058.

High-resolution structure of a modular hyperthermostable endo-beta-1,4-mannanase from Thermotoga petrophila: The ancillary immunoglobulin-like module is a thermostabilizing domain. (Mus musculus) PubMed

 26059.

Construction expression and immunogenicity of a novel trivalent outer membrane protein (OmpU-A-II) from three bacterial pathogens in Japanese eels (Anguilla japonica). (Mus musculus) PubMed

 26060.

Seryl-tRNA synthetase specificity for tRNA(Sec) in Bacterial Sec biosynthesis. (Mus musculus) PubMed

 26061.

The Sec1/Munc18-like proteins TgSec1 and TgVps45 play pivotal roles in assembly of the pellicle and sub-pellicle network in Toxoplasma gondii. (Mus musculus) PubMed

 26062.

The viral suppressor HCPro decreases DNA methylation and activates auxin biosynthesis genes. (Mus musculus) PubMed

 26063.

Functional characterisation and in silico modelling of MdPSY2 variants and MdPSY5 phytoene synthases from Malus domestica. (Mus musculus) PubMed

 26064.

Construction expression and immunogenicity of a novel trivalent outer membrane protein (OmpU-A-II) from three bacterial pathogens in Japanese eels (Anguilla japonica). (Mus musculus) PubMed

 26065.

Effects of available phosphorus source and concentration on performance and expression of sodium phosphate type IIb cotransporter, vitamin D-1alpha-hydroxylase, and vitamin D-24-hydroxylase mRNA in broiler chicks. (Mus musculus) PubMed

 26066.

Inactivation of the Levansucrase Gene in Paenibacillus polymyxa DSM 365 Diminishes Exopolysaccharide Biosynthesis during 2,3-Butanediol Fermentation. (Mus musculus) PubMed

 26067.

Functional interactions between gyrase subunits are optimized in a species-specific manner. (Mus musculus) PubMed

 26068.

Analysis of Global Collection of Group A Streptococcus Genomes Reveals that the Majority Encode a Trio of M and M-Like Proteins. (Mus musculus) PubMed

 26069.

Highly regio- and stereoselective hydroxylation of vitamin D2 by CYP109E1. (Mus musculus) PubMed

 26070.

Functional interactions between gyrase subunits are optimized in a species-specific manner. (Mus musculus) PubMed

 26071.

The topology of the ER-resident phospholipid methyltransferase Opi3 of Saccharomyces cerevisiae is consistent with in trans catalysis. (Mus musculus) PubMed

 26072.

Functional interactions between gyrase subunits are optimized in a species-specific manner. (Mus musculus) PubMed

 26073.

Systematic Analysis of the Maize OSCA Genes Revealing ZmOSCA Family Members Involved in Osmotic Stress and ZmOSCA2.4 Confers Enhanced Drought Tolerance in Transgenic Arabidopsis. (Mus musculus) PubMed

 26074.

GlnR Negatively Regulates Glutamate-Dependent Acid Resistance in Lactobacillus brevis. (Mus musculus) PubMed

 26075.

Weak Acid Resistance A (WarA), a Novel Transcription Factor Required for Regulation of Weak-Acid Resistance and Spore-Spore Heterogeneity in Aspergillus niger. (Mus musculus) PubMed

 26076.

Motif V regulates energy transduction between the flavivirus NS3 ATPase and RNA-binding cleft. (Mus musculus) PubMed

 26077.

Role of yoaE Gene Regulated by CpxR in the Survival of Salmonella enterica Serovar Enteritidis in Antibacterial Egg White. (Mus musculus) PubMed

 26078.

Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Regulate Maturation of the Cyst Wall. (Mus musculus) PubMed

 26079.

Investigation of PRDM7 and PRDM12 expression pattern during mouse embryonic development by using a modified passive clearing technique. (Mus musculus) PubMed

 26080.

Changes in colistin resistance and mcr-1 abundance in Escherichia coli of animal and human origins following the ban of colistin-positive additives in China: an epidemiological comparative study. (Mus musculus) PubMed

 26081.

Epstein-Barr virus-encoded miR-BART11 promotes tumor-associated macrophage-induced epithelial-mesenchymal transition via targeting FOXP1 in gastric cancer. (Mus musculus) PubMed

 26082.

Regulation of Lin28a-miRNA let-7b-5p pathway in skeletal muscle cells by peroxisome proliferator-activated receptor delta. (Mus musculus) PubMed

 26083.

Insights into the global effect on Staphylococcus aureus growth arrest by induction of the endoribonuclease MazF toxin. (Mus musculus) PubMed

 26084.

Mechanistic basis of substrate-O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study. (Mus musculus) PubMed

 26085.

The roles of long-range proton-coupled electron transfer in the directionality and efficiency of [FeFe]-hydrogenases. (Mus musculus) PubMed

 26086.

The role of disulfide bonds in a Solanum tuberosum saposin-like protein investigated using molecular dynamics. (Mus musculus) PubMed

 26087.

Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis. (Mus musculus) PubMed

 26088.

TssA-TssM-TagA interaction modulates type VI secretion system sheath-tube assembly in Vibrio cholerae. (Mus musculus) PubMed

 26089.

The Chlamydia trachomatis secreted effector TmeA hijacks the N-WASP-ARP2/3 actin remodeling axis to facilitate cellular invasion. (Mus musculus) PubMed

 26090.

Human parainfluenza virus fusion complex glycoproteins imaged in action on authentic viral surfaces. (Mus musculus) PubMed

 26091.

Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8. (Mus musculus) PubMed

 26092.

A Plasmodium cysteine protease required for efficient transition from the liver infection stage. (Mus musculus) PubMed

 26093.

Quantum chemical insight into molecular structure, NBO analysis of the hydrogen-bonded interactions, spectroscopic (FT-IR, FT-Raman), drug likeness and molecular docking of the novel anti COVID-19 molecule 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide - dimer. (Mus musculus) PubMed

 26094.

Room-temperature neutron and X-ray data collection of 3CL M(pro) from SARS-CoV-2. (Mus musculus) PubMed

 26095.

The natural phytochemical trans-communic acid inhibits cellular senescence and pigmentation through FoxO3a activation. (Mus musculus) PubMed

 26096.

Dual role of the colonization factor CD2831 in Clostridium difficile pathogenesis. (Mus musculus) PubMed

 26097.

Biosynthesis of Hyaluronic acid polymer: Dissecting the role of sub structural elements of hyaluronan synthase. (Mus musculus) PubMed

 26098.

Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus. (Mus musculus) PubMed

 26099.

Exploring Plasmodium falciparum Var Gene Expression to Assess Host Selection Pressure on Parasites During Infancy. (Mus musculus) PubMed

 26100.

AflSte20 Regulates Morphogenesis, Stress Response, and Aflatoxin Biosynthesis of Aspergillus flavus. (Mus musculus) PubMed

 26101.

SoxS is a positive regulator of key pathogenesis genes and promotes intracellular replication and virulence of Salmonella Typhimurium. (Mus musculus) PubMed

 26102.

Mycobacterial phosphatase PstP regulates global serine threonine phosphorylation and cell division. (Mus musculus) PubMed

 26103.

Streptococcus suis suilysin compromises the function of a porcine tracheal epithelial barrier model. (Mus musculus) PubMed

 26104.

Antisense peptide nucleic acids againstftsZ andefaA genes inhibit growth and biofilm formation of Enterococcusfaecalis. (Mus musculus) PubMed

 26105.

ClpB is an essential stress regulator of Mycobacterium tuberculosis and endows survival advantage to dormant bacilli. (Mus musculus) PubMed

 26106.

Cloning and characterization of the virulence factor Hop from Vibrio splendidus. (Mus musculus) PubMed

 26107.

The LisH Domain-Containing N-Terminal Fragment is Important for the Localization, Dimerization, and Stability of Katnal2 in Tetrahymena. (Mus musculus) PubMed

 26108.

The role of the miR1976/CD105/integrin alphavbeta6 axis in vaginitis induced by Escherichia coli infection in mice. (Mus musculus) PubMed

 26109.

Kisspeptin/Neurokinin B/Dynorphin (KNDy) cells as integrators of diverse internal and external cues: evidence from viral-based monosynaptic tract-tracing in mice. (Mus musculus) PubMed

 26110.

A PQ-loop protein Ypq2 is involved in the exchange of arginine and histidine across the vacuolar membrane of Saccharomyces cerevisiae. (Mus musculus) PubMed

 26111.

Solution structure, glycan specificity and of phenol oxidase inhibitory activity of Anopheles C-type lectins CTL4 and CTLMA2. (Mus musculus) PubMed

 26112.

Binding partner- and force-promoted changes in alphaE-catenin conformation probed by native cysteine labeling. (Mus musculus) PubMed

 26113.

Convergent evolution of processivity in bacterial and fungal cellulases. (Mus musculus) PubMed

 26114.

Convergent evolution of processivity in bacterial and fungal cellulases. (Mus musculus) PubMed

 26115.

Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase. (Mus musculus) PubMed

 26116.

Understanding the survival mechanisms of Deinococcus radiodurans against oxidative stress by targeting thioredoxin reductase redox system. (Mus musculus) PubMed

 26117.

A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus. (Mus musculus) PubMed

 26118.

Transcriptional regulator ArcA mediates expression of oligopeptide transport systems both directly and indirectly in Shewanella oneidensis. (Mus musculus) PubMed

 26119.

Local Self-Enhancement of MinD Membrane Binding in Min Protein Pattern Formation. (Mus musculus) PubMed

 26120.

Methionine Availability in the Arthropod Intestine Is Elucidated through Identification of Vibrio cholerae Methionine Acquisition Systems. (Mus musculus) PubMed

 26121.

A distinct inhibitory mechanism of the V-ATPase by Vibrio VopQ revealed by cryo-EM. (Mus musculus) PubMed

 26122.

Transcriptome Analysis Reveals IsiA-Regulatory Mechanisms Underlying Iron Depletion and Oxidative-Stress Acclimation in Synechocystis sp. Strain PCC 6803. (Mus musculus) PubMed

 26123.

Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis. (Mus musculus) PubMed

 26124.

Dissecting the Functional Contributions of the Intrinsically Disordered C-terminal Tail of Bacillus subtilis FtsZ. (Mus musculus) PubMed

 26125.

Multifunctional Acidocin 4356 Combats Pseudomonas aeruginosa through Membrane Perturbation and Virulence Attenuation: Experimental Results Confirm Molecular Dynamics Simulation. (Mus musculus) PubMed

 26126.

Mutation of Conserved Mre11 Residues Alter Protein Dynamics to Separate Nuclease Functions. (Mus musculus) PubMed

 26127.

Ferric Uptake Regulator Provides a New Strategy for Acidophile Adaptation to Acidic Ecosystems. (Mus musculus) PubMed

 26128.

AccR, a TetR Family Transcriptional Repressor, Coordinates Short-Chain Acyl Coenzyme A Homeostasis in Streptomyces avermitilis. (Mus musculus) PubMed

 26129.

Both Enolase and the DEAD-Box RNA Helicase CrhB Can Form Complexes with RNase E in Anabaena sp. Strain PCC 7120. (Mus musculus) PubMed

 26130.

The N-Acetylglucosaminidase LytB of Streptococcus pneumoniae Is Involved in the Structure and Formation of Biofilms. (Mus musculus) PubMed

 26131.

CosR Is a Global Regulator of the Osmotic Stress Response with Widespread Distribution among Bacteria. (Mus musculus) PubMed

 26132.

Cytophaga hutchinsonii gldN, Encoding a Core Component of the Type IX Secretion System, Is Essential for Ion Assimilation, Cellulose Degradation, and Cell Motility. (Mus musculus) PubMed

 26133.

Aquaporin expression in the alimentary canal of the honey bee Apis mellifera L. (Hymenoptera: Apidae) and functional characterization of Am_Eglp 1. (Mus musculus) PubMed

 26134.

Target search and recognition mechanisms of glycosylase AlkD revealed by scanning FRET-FCS and Markov state models. (Mus musculus) PubMed

 26135.

The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation. (Mus musculus) PubMed

 26136.

PilY1 and minor pilins form a complex priming the type IVa pilus in Myxococcus xanthus. (Mus musculus) PubMed

 26137.

Newly detected mutations in the Meq oncogene and molecular pathotyping of very virulent Marek's disease herpesvirus in Tunisia. (Mus musculus) PubMed

 26138.

Clinical characteristics and prevalence of dihydropteroate synthase gene mutations in Pneumocystis jirovecii-infected AIDS patients from low endemic areas of China. (Mus musculus) PubMed

 26139.

SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. (Mus musculus) PubMed

 26140.

Histone-like Nucleoid-Structuring Protein (H-NS) Paralogue StpA Activates the Type I-E CRISPR-Cas System against Natural Transformation in Escherichia coli. (Mus musculus) PubMed

 26141.

Infectious hematopoietic necrosis virus N protein suppresses fish IFN1 production by targeting the MITA. (Mus musculus) PubMed

 26142.

TaAPO-A1, an ortholog of rice ABERRANT PANICLE ORGANIZATION 1, is associated with total spikelet number per spike in elite European hexaploid winter wheat (Triticum aestivum L.) varieties. (Mus musculus) PubMed

 26143.

Structure and Dynamics of the Rhomboid Protease GlpG in Liposomes Studied by Solid-State NMR. (Mus musculus) PubMed

 26144.

Use of paramagnetic (19)F NMR to monitor domain movement in a glutamate transporter homolog. (Mus musculus) PubMed

 26145.

Structural insights into telomere protection and homeostasis regulation by yeast CST complex. (Mus musculus) PubMed

 26146.

Xylose-Inducible Promoter Tools for Pseudomonas Species and Their Use in Implicating a Role for the Type II Secretion System Protein XcpQ in the Inhibition of Corneal Epithelial Wound Closure. (Mus musculus) PubMed

 26147.

ABC Transporter DerAB of Lactobacillus casei Mediates Resistance against Insect-Derived Defensins. (Mus musculus) PubMed

 26148.

LncRNA THRIL aggravates sepsis-induced acute lung injury by regulating miR-424/ROCK2 axis. (Mus musculus) PubMed

 26149.

Interaction of human hemoglobin and semi-hemoglobins with the Staphylococcus aureus hemophore IsdB: a kinetic and mechanistic insight. (Mus musculus) PubMed

 26150.

Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. (Mus musculus) PubMed

 26151.

Small grain and semi-dwarf 3, a WRKY transcription factor, negatively regulates plant height and grain size by stabilizing SLR1 expression in rice. (Mus musculus) PubMed

 26152.

Os4BGlu14, a monolignol beta-Glucosidase, negatively affects seed longevity by influencing primary metabolism in rice. (Mus musculus) PubMed

 26153.

A CRISPR-associated factor Csa3a regulates DNA damage repair in Crenarchaeon Sulfolobus islandicus. (Mus musculus) PubMed

 26154.

The conserved ribonuclease aCPSF1 triggers genome-wide transcription termination of Archaea via a 3'-end cleavage mode. (Mus musculus) PubMed

 26155.

Expression profile of kalliklectin, a soluble-type mannose receptor, during embryogenesis and early larval development in fugu (Takifugu rubripes). (Mus musculus) PubMed

 26156.

OsJAZ9 overexpression modulates jasmonic acid biosynthesis and potassium deficiency responses in rice. (Mus musculus) PubMed

 26157.

Genome maintenance functions of a putative Trypanosoma brucei translesion DNA polymerase include telomere association and a role in antigenic variation. (Mus musculus) PubMed

 26158.

Prophylactic potential of cytolethal distending toxin B (CdtB) subunit of typhoid toxin against Typhoid fever. (Mus musculus) PubMed

 26159.

An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity. (Mus musculus) PubMed

 26160.

Structural genomics applied to the rust fungus Melampsora larici-populina reveals two candidate effector proteins adopting cystine knot and NTF2-like protein folds. (Mus musculus) PubMed

 26161.

The Leptospira interrogans LIC10774 is a multifunctional surface protein that binds calcium and interacts with host components. (Mus musculus) PubMed

 26162.

Functional Characterization of Cj1427, a Unique Ping-Pong Dehydrogenase Responsible for the Oxidation of GDP-d-glycero-alpha-d-manno-heptose in Campylobacter jejuni. (Mus musculus) PubMed

 26163.

Structural Analysis of Cj1427, an Essential NAD-Dependent Dehydrogenase for the Biosynthesis of the Heptose Residues in the Capsular Polysaccharides of Campylobacter jejuni. (Mus musculus) PubMed

 26164.

Exploiting species specificity to understand the tropism of a human-specific toxin. (Mus musculus) PubMed

 26165.

A molecular rack and pinion actuates a cell-surface adhesin and enables bacterial gliding motility. (Mus musculus) PubMed

 26166.

Consensus Mutagenesis and Ancestral Reconstruction Provide Insight into the Substrate Specificity and Evolution of the Front-End Delta6-Desaturase Family. (Mus musculus) PubMed

 26167.

Consensus Mutagenesis and Ancestral Reconstruction Provide Insight into the Substrate Specificity and Evolution of the Front-End Delta6-Desaturase Family. (Mus musculus) PubMed

 26168.

Inverse control of Rab proteins by Yersinia ADP-ribosyltransferase and glycosyltransferase related to clostridial glucosylating toxins. (Mus musculus) PubMed

 26169.

X-ray Crystal Structure of the Influenza A M2 Proton Channel S31N Mutant in Two Conformational States: An Open and Shut Case. (Mus musculus) PubMed

 26170.

New insights into the ORF2 capsid protein, a key player of the hepatitis E virus lifecycle. (Mus musculus) PubMed

 26171.

Sequence-based mapping identifies a candidate transcription repressor underlying awn suppression at the B1 locus in wheat. (Mus musculus) PubMed

 26172.

Dominant inhibition of awn development by a putative zinc-finger transcriptional repressor expressed at the B1 locus in wheat. (Mus musculus) PubMed

 26173.

Aryl hydrocarbon receptor is required for immune response in Epinephelus coioides and Danio rerio infected by Pseudomonas plecoglossicida. (Mus musculus) PubMed

 26174.

Pig liver esterases PLE1 and PLE6: heterologous expression, hydrolysis of common antibiotics and pharmacological consequences. (Mus musculus) PubMed

 26175.

Global translational repression induced by iron deficiency in yeast depends on the Gcn2/eIF2alpha pathway. (Mus musculus) PubMed

 26176.

The semidominant mutation w5 impairs epicuticular wax deposition in common wheat (Triticum aestivum L.). (Mus musculus) PubMed

 26177.

Acetylation of lysine 7 of AhyI affects the biological function in Aeromonas hydrophila. (Mus musculus) PubMed

 26178.

Functional characterization of the type I toxin Lpt from Lactobacillus rhamnosus by fluorescence and atomic force microscopy. (Mus musculus) PubMed

 26179.

The mutation of a PECTATE LYASE-LIKE gene is responsible for the Yellow Margin phenotype in potato. (Mus musculus) PubMed

 26180.

AP-1 regulates the expression of IL17-4 and IL17-5 in the pacific oyster Crassostrea gigas. (Mus musculus) PubMed

 26181.

The Autophagy Regulatory Molecule CSRP3 Interacts with LC3 and Protects Against Muscular Dystrophy. (Mus musculus) PubMed

 26182.

Hepatitis C Virus p7 Induces Membrane Permeabilization by Interacting with Phosphatidylserine. (Mus musculus) PubMed

 26183.

Fine mapping of wheat powdery mildew resistance gene Pm6 using 2B/2G homoeologous recombinants induced by the ph1b mutant. (Mus musculus) PubMed

 26184.

Thr420 and Ser454 of ZmCCaMK play a crucial role in brassinosteroid-induced antioxidant defense in maize. (Mus musculus) PubMed

 26185.

Structural characterization and in-silico analysis of Momordica charantia 7S globulin for stability and ACE inhibition. (Mus musculus) PubMed

 26186.

Mutational diversity in mutY deficient Helicobacter pylori and its effect on adaptation to the gastric environment. (Mus musculus) PubMed

 26187.

Detection of Beijing strains of MDR M. tuberculosis and their association with drug resistance mutations in katG, rpoB, and embB genes. (Mus musculus) PubMed

 26188.

MERISTEM ACTIVITYLESS (MAL) is involved in root development through maintenance of meristem size in rice. (Mus musculus) PubMed

 26189.

Fluconazole-resistant Candida parapsilosis strains with a Y132F substitution in the ERG11 gene causing invasive infections in a neonatal unit, South Africa. (Mus musculus) PubMed

 26190.

The ex planta signal activity of a Medicago ribosomal uL2 protein suggests a moonlighting role in controlling secondary rhizobial infection. (Mus musculus) PubMed

 26191.

Bovine papillomavirus E5 oncoprotein upregulates parkin-dependent mitophagy in urothelial cells of cattle with spontaneous papillomavirus infection: A mechanistic study. (Mus musculus) PubMed

 26192.

Comparison of the functional properties of trimeric and monomeric CaiT of Escherichia coli. (Mus musculus) PubMed

 26193.

Mechanism of aminoacyl-tRNA acetylation by an aminoacyl-tRNA acetyltransferase AtaT from enterohemorrhagic E. coli. (Mus musculus) PubMed

 26194.

Overexpression of TaJAZ1 increases powdery mildew resistance through promoting reactive oxygen species accumulation in bread wheat. (Mus musculus) PubMed

 26195.

DEGENERATED PANICLE AND PARTIAL STERILITY 1 (DPS1) encodes a cystathionine beta-synthase domain containing protein required for anther cuticle and panicle development in rice. (Mus musculus) PubMed

 26196.

Membrane directed expression in Escherichia coli of BBA57 and other virulence factors from the Lyme disease agent Borrelia burgdorferi. (Mus musculus) PubMed

 26197.

Cauliflower mosaic virus transactivator protein (TAV) can suppress nonsense-mediated decay by targeting VARICOSE, a scaffold protein of the decapping complex. (Mus musculus) PubMed

 26198.

Intramuscular Immunization of Streptococcus pyogenes SF370 protein extract and identification of multiple virulence factors through proteomic profiling in RHD induced Balb/c mice. (Mus musculus) PubMed

 26199.

CgRel involved in antibacterial immunity by regulating the production of CgIL17s and CgBigDef1 in the Pacific oyster Crassostrea gigas. (Mus musculus) PubMed

 26200.

Truncation of CXCL8 to CXCL8(9-77) enhances actin polymerization and in vivo migration of neutrophils. (Mus musculus) PubMed

 26201.

Structural characterization of beta-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites. (Mus musculus) PubMed

 26202.

Molecular Characterization of Auxin Efflux Carrier- ABCB1 in hexaploid wheat. (Mus musculus) PubMed

 26203.

Molecular characterization of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae from a Malaysian hospital. (Mus musculus) PubMed

 26204.

SpoVG Modulates Cell Aggregation in Staphylococcus aureus by Regulating sasC Expression and Extracellular DNA Release. (Mus musculus) PubMed

 26205.

CheY1 and CheY2 of Azorhizobium caulinodans ORS571 Regulate Chemotaxis and Competitive Colonization with the Host Plant. (Mus musculus) PubMed

 26206.

SARS-CoV-2 ORF3b Is a Potent Interferon Antagonist Whose Activity Is Increased by a Naturally Occurring Elongation Variant. (Mus musculus) PubMed

 26207.

Global Regulator of Rubber Degradation in Gordonia polyisoprenivorans VH2: Identification and Involvement in the Regulation Network. (Mus musculus) PubMed

 26208.

Ghrelin Selectively Inhibits CaV3.3 Subtype of Low-Voltage-Gated Calcium Channels. (Mus musculus) PubMed

 26209.

Interactions of replication initiator RctB with single- and double-stranded DNA in origin opening of Vibrio cholerae chromosome 2. (Mus musculus) PubMed

 26210.

Staphylococcus aureus toxin suppresses antigen-specific T cell responses. (Mus musculus) PubMed

 26211.

FACT and Ash1 promote long-range and bidirectional nucleosome eviction at the HO promoter. (Mus musculus) PubMed

 26212.

HilD induces expression of a novel Salmonella Typhimurium invasion factor, YobH, through a regulatory cascade involving SprB. (Mus musculus) PubMed

 26213.

Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNgamma-activated murine macrophages. (Mus musculus) PubMed

 26214.

Force-clamp spectroscopy identifies a catch bond mechanism in a Gram-positive pathogen. (Mus musculus) PubMed

 26215.

Long noncoding RNA UC.98 stabilizes atherosclerotic plaques by promoting the proliferation and adhesive capacity in murine aortic endothelial cells. (Mus musculus) PubMed

 26216.

Structural basis for -35 element recognition by sigma4 chimera proteins and their interactions with PmrA response regulator. (Mus musculus) PubMed

 26217.

CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy. (Mus musculus) PubMed

 26218.

An NMR and MD study of complexes of bacteriophage lambda lysozyme with tetra- and hexa-N-acetylchitohexaose. (Mus musculus) PubMed

 26219.

Characterization of Streptococcus iniae-induced microRNA profiles in Paralichthys olivaceus and identification of pol-3p-10740_175 as a regulator of antibacterial immune response. (Mus musculus) PubMed

 26220.

Adipokinetic hormone regulates cytochrome P450-mediated imidacloprid resistance in the brown planthopper, Nilaparvata lugens. (Mus musculus) PubMed

 26221.

Distinct oligomeric structures of the YoeB-YefM complex provide insights into the conditional cooperativity of type II toxin-antitoxin system. (Mus musculus) PubMed

 26222.

LSD1 prevents aberrant heterochromatin formation in Neurospora crassa. (Mus musculus) PubMed

 26223.

Impact of Early Pandemic Stage Mutations on Molecular Dynamics of SARS-CoV-2 M(pro). (Mus musculus) PubMed

 26224.

Synthesis runs counter to directional folding of a nascent protein domain. (Mus musculus) PubMed

 26225.

Conformational equilibrium shift underlies altered K(+) channel gating as revealed by NMR. (Mus musculus) PubMed

 26226.

Identification of a major dominant gene for race-nonspecific tan spot resistance in wild emmer wheat. (Mus musculus) PubMed

 26227.

Molecular detection of drug resistant polymorphisms in Plasmodium falciparum isolates from Southwest, Nigeria. (Mus musculus) PubMed

 26228.

Immunodominant proteins P1 and P40/P90 from human pathogen Mycoplasma pneumoniae. (Mus musculus) PubMed

 26229.

Phenotypic, genetic, and molecular function of msc-2, a genic male sterile mutant in pepper (Capsicum annuum L.). (Mus musculus) PubMed

 26230.

Fine mapping of restorer-of-fertility gene based on high-density genetic mapping and collinearity analysis in pepper (Capsicum annuum L.). (Mus musculus) PubMed

 26231.

Reactivity of an Unusual Amidase May Explain Colibactin's DNA Cross-Linking Activity. (Mus musculus) PubMed

 26232.

Disruption of hmgA by DNA Duplication is Responsible for Hyperpigmentation in a Vibrio anguillarum Strain. (Mus musculus) PubMed

 26233.

HspX promotes the polar localization of mycobacterial protein aggregates. (Mus musculus) PubMed

 26234.

An evolution-based designing and characterization of mutants of cyclomaltodextrinase: Molecular modeling and spectroscopic studies. (Mus musculus) PubMed

 26235.

Molecular cloning and the involvement of IRE1alpha-XBP1s signaling pathway in palmitic acid induced - Inflammation in primary hepatocytes from large yellow croaker (Larimichthys crocea). (Mus musculus) PubMed

 26236.

Characterization of CYP71AX36 from Sunflower (Helianthus annuus L., Asteraceae). (Mus musculus) PubMed

 26237.

Perception of Agrobacterium tumefaciens flagellin by FLS2(XL) confers resistance to crown gall disease. (Mus musculus) PubMed

 26238.

YqfB protein from Escherichia coli: an atypical amidohydrolase active towards N(4)-acylcytosine derivatives. (Mus musculus) PubMed

 26239.

What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein. (Mus musculus) PubMed

 26240.

QTL mapping and successful introgression of the spring wheat-derived QTL Fhb1 for Fusarium head blight resistance in three European triticale populations. (Mus musculus) PubMed

 26241.

Essential ion binding residues for Na(+) flow in stator complex of the Vibrio flagellar motor. (Mus musculus) PubMed

 26242.

c-di-GMP-related phenotypes are modulated by the interaction between a diguanylate cyclase and a polar hub protein. (Mus musculus) PubMed

 26243.

Transcription in the acetoin catabolic pathway is regulated by AcoR and CcpA in Bacillus thuringiensis. (Mus musculus) PubMed

 26244.

Identification and characterization of an R-Smad homologue (Hco-DAF-8) from Haemonchus contortus. (Mus musculus) PubMed

 26245.

Deletion of Herpes Simplex Virus 1 MicroRNAs miR-H1 and miR-H6 Impairs Reactivation. (Mus musculus) PubMed

 26246.

Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail. (Mus musculus) PubMed

 26247.

Beta Human Papillomavirus 8E6 Attenuates LATS Phosphorylation after Failed Cytokinesis. (Mus musculus) PubMed

 26248.

Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking. (Mus musculus) PubMed

 26249.

Transcriptomic analysis of PhoR reveals its role in regulation of swarming motility and T3SS expression in Vibrio parahaemolyticus. (Mus musculus) PubMed

 26250.

Major Capsid Protein Synthesis from the Genomic RNA of Feline Calicivirus. (Mus musculus) PubMed

 26251.

Per Os Infectivity Factor 5 Identified as a Substrate of P33 in the Baculoviral Disulfide Bond Formation Pathway. (Mus musculus) PubMed

 26252.

Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression. (Mus musculus) PubMed

 26253.

Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis. (Mus musculus) PubMed

 26254.

A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers. (Mus musculus) PubMed

 26255.

High frequency of the exoU+/exoS+ genotype associated with multidrug-resistant ""high-risk clones"" of Pseudomonas aeruginosa clinical isolates from Peruvian hospitals. (Mus musculus) PubMed

 26256.

Intact pap2 downstream of mcr-1 appears to be required for colistin resistance. (Mus musculus) PubMed

 26257.

Substrate-Based Allosteric Regulation of a Homodimeric Enzyme. (Mus musculus) PubMed

 26258.

Substrate Activation of the Low-Molecular Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis. (Mus musculus) PubMed

 26259.

Structural Characterization of the Helicase nsp10 Encoded by Porcine Reproductive and Respiratory Syndrome Virus. (Mus musculus) PubMed

 26260.

The tetrameric structure of nucleotide-regulated pyrophosphatase and its modulation by deletion mutagenesis and ligand binding. (Mus musculus) PubMed

 26261.

Structural features of the interaction of MapZ with FtsZ and membranes in Streptococcus pneumoniae. (Mus musculus) PubMed

 26262.

Orphan response regulator Rv3143 increases antibiotic sensitivity by regulating cell wall permeability in Mycobacterium smegmatis. (Mus musculus) PubMed

 26263.

A Haloalkane Dehalogenase from Saccharomonospora viridis Strain DSM 43017, a Compost Bacterium with Unusual Catalytic Residues, Unique (S)-Enantiopreference, and High Thermostability. (Mus musculus) PubMed

 26264.

Engineering a Carotenoid-Overproducing Strain of Azospirillum brasilense for Heterologous Production of Geraniol and Amorphadiene. (Mus musculus) PubMed

 26265.

DNM1, a Dynamin-Related Protein That Contributes to Endocytosis and Peroxisome Fission, Is Required for the Vegetative Growth, Sporulation, and Virulence of Metarhizium robertsii. (Mus musculus) PubMed

 26266.

Palmitvaccenic Acid (Delta11-cis-hexadecenoic acid) Is Synthesized by an OLE1-like Desaturase in the Arbuscular Mycorrhiza Fungus Rhizophagus irregularis. (Mus musculus) PubMed

 26267.

Flexibility modulates the catalytic activity of a thermostable enzyme: key information from optical spectroscopy and molecular dynamics simulation. (Mus musculus) PubMed

 26268.

Introgression of Sub1 (SUB1) QTL in mega rice cultivars increases ethylene production to the detriment of grain- filling under stagnant flooding. (Mus musculus) PubMed

 26269.

Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus. (Mus musculus) PubMed

 26270.

Effects of microRNA-731 on inflammation and apoptosis by targeting CiGadd45aa in grass carp. (Mus musculus) PubMed

 26271.

AdeB efflux pump gene knockdown by mRNA mediated peptide nucleic acid in multidrug resistance Acinetobacter baumannii. (Mus musculus) PubMed

 26272.

Structural exploration of glutamine synthetase from Leishmania donovani: Insights from in silico and in vitro analysis. (Mus musculus) PubMed

 26273.

lncRNACNN3-206 activates intestinal epithelial cell apoptosis and invasion by sponging miR-212, an implication for Crohn's disease. (Mus musculus) PubMed

 26274.

Cooperative unfolding of a single-layer beta-sheet protein, CPAP G-box. (Mus musculus) PubMed

 26275.

Nonsense Mutations in the Yeast SUP35 Gene Affect the [PSI(+)] Prion Propagation. (Mus musculus) PubMed

 26276.

A xylan glucuronosyltransferase gene exhibits pleiotropic effects on cellular composition and leaf development in rice. (Mus musculus) PubMed

 26277.

Trypanosoma brucei RAP1 Has Essential Functional Domains That Are Required for Different Protein Interactions. (Mus musculus) PubMed

 26278.

Survival factor SvfA plays multiple roles in differentiation and is essential for completion of sexual development in Aspergillus nidulans. (Mus musculus) PubMed

 26279.

Role of Toxin-Antitoxin-Regulated Persister Population and Indole in Bacterial Heat Tolerance. (Mus musculus) PubMed

 26280.

First report of AChE1 (G119S) mutation and multiple resistance mechanisms in Anopheles gambiae s.s. in Nigeria. (Mus musculus) PubMed

 26281.

Exploration of Two Pectate Lyases from Caldicellulosiruptor bescii Reveals that the CBM66 Module Has a Crucial Role in Pectic Biomass Degradation. (Mus musculus) PubMed

 26282.

Another Breaker of the Wall: the Biological Function of the Usp45 Protein of Lactococcus lactis. (Mus musculus) PubMed

 26283.

Expression of cannabinoid CB1 R-GPR55 heteromers in neuronal subtypes of the Macaca fascicularis striatum. (Mus musculus) PubMed

 26284.

Screening and Evaluation of New Hydroxymethylfurfural Oxidases for Furandicarboxylic Acid Production. (Mus musculus) PubMed

 26285.

The CARF Protein MM_0565 Affects Transcription of the Casposon-Encoded cas1-solo Gene in Methanosarcina mazei Go1. (Mus musculus) PubMed

 26286.

Protective Effect of Circular RNA (CircRNA) Ddx17 in Ovalbumin (OVA)-Induced Allergic Rhinitis (AR) Mice. (Mus musculus) PubMed

 26287.

A novel Plasmodium yoelii pseudokinase, PypPK1, is involved in erythrocyte invasion and exflagellation center formation. (Mus musculus) PubMed

 26288.

Azorhizobium caulinodans c-di-GMP phosphodiesterase Chp1 involved in motility, EPS production, and nodulation of the host plant. (Mus musculus) PubMed

 26289.

Regulation of spermatogenesis and reproductive capacity by Igf3 in tilapia. (Mus musculus) PubMed

 26290.

Trypanosoma brucei Pex13.2 Is an Accessory Peroxin That Functions in the Import of Peroxisome Targeting Sequence Type 2 Proteins and Localizes to Subdomains of the Glycosome. (Mus musculus) PubMed

 26291.

Role of Bm30kc6 gene in cell apoptosis and the silk gland degradation signaling pathway in Bombyx mori L. (Mus musculus) PubMed

 26292.

Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion. (Mus musculus) PubMed

 26293.

Coimmunoprecipitation with MYR1 Identifies Three Additional Proteins within the Toxoplasma gondii Parasitophorous Vacuole Required for Translocation of Dense Granule Effectors into Host Cells. (Mus musculus) PubMed

 26294.

The Secreted Acid Phosphatase Domain-Containing GRA44 from Toxoplasma gondii Is Required for c-Myc Induction in Infected Cells. (Mus musculus) PubMed

 26295.

MAG2, a Toxoplasma gondii Bradyzoite Stage-Specific Cyst Matrix Protein. (Mus musculus) PubMed

 26296.

Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2 pandemic. (Mus musculus) PubMed

 26297.

NusA directly interacts with antitermination factor Q from phage lambda. (Mus musculus) PubMed

 26298.

ArfB can displace mRNA to rescue stalled ribosomes. (Mus musculus) PubMed

 26299.

Predictive design of sigma factor-specific promoters. (Mus musculus) PubMed

 26300.

Identification of a novel bacterial receptor that binds tail tubular proteins and mediates phage infection of Vibrio parahaemolyticus. (Mus musculus) PubMed

 26301.

Phase variation in latB associated with a fatal Pasteurella multocida outbreak in captive squirrel gliders. (Mus musculus) PubMed

 26302.

Predictive design of sigma factor-specific promoters. (Mus musculus) PubMed

 26303.

Snf5 and Swi3 subcomplex formation is required for SWI/SNF complex function in yeast. (Mus musculus) PubMed

 26304.

RanB, a putative ABC-type multidrug efflux transporter contributes to aminoglycosides resistance and organic solvents tolerance in Riemerella anatipestifer. (Mus musculus) PubMed

 26305.

A stripe rust effector Pst18363 targets and stabilises TaNUDX23 that promotes stripe rust disease. (Mus musculus) PubMed

 26306.

Rice black-streaked dwarf virus-encoded P5-1 regulates the ubiquitination activity of SCF E3 ligases and inhibits jasmonate signaling to benefit its infection in rice. (Mus musculus) PubMed

 26307.

The H3K4 demethylase Jar1 orchestrates ROS production and expression of pathogenesis-related genes to facilitate Botrytis cinerea virulence. (Mus musculus) PubMed

 26308.

Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase. (Mus musculus) PubMed

 26309.

Genetic diversity of the intimin gene (eae) in non-O157 Shiga toxin-producing Escherichia coli strains in China. (Mus musculus) PubMed

 26310.

Specific binding of DnaA to the DnaA box motif in the cyanobacterium Synechococcus elongatus PCC 7942. (Mus musculus) PubMed

 26311.

A polyketide synthase HglEA, but not HglE2, synthesizes heterocyst specific glycolipids in Anabaena sp. PCC 7120. (Mus musculus) PubMed

 26312.

Wheat PP2C-a10 regulates seed germination and drought tolerance in transgenic Arabidopsis. (Mus musculus) PubMed

 26313.

Yersinia ruckeri strain SC09 disrupts proinflammatory activation via Toll/IL-1 receptor-containing protein STIR-3. (Mus musculus) PubMed

 26314.

SHP1 tyrosine phosphatase gets involved in host defense against Streptococcus agalactiae infection and BCR signaling pathway in Nile tilapia (Oreochromis niloticus). (Mus musculus) PubMed

 26315.

Verticillium dahliae VdTHI20, Involved in Pyrimidine Biosynthesis, Is Required for DNA Repair Functions and Pathogenicity. (Mus musculus) PubMed

 26316.

An activating transcription factor 6 beta (ATF6beta) regulates apoptosis of hemocyte during immune response in Crassostrea gigas. (Mus musculus) PubMed

 26317.

A novel programmed cell death protein 4 negatively regulates CgIL17-5 expression in hemocytes of oyster Pacific oyster (Crassostrea gigas). (Mus musculus) PubMed

 26318.

Functional characterization of two ecto-nucleoside triphosphate diphosphohydrolase 2 genes in Japanese flounder (Paralichthys olivaceus) head kidney macrophages. (Mus musculus) PubMed

 26319.

NK-lysin is highly conserved in European sea bass and gilthead seabream but differentially modulated during the immune response. (Mus musculus) PubMed

 26320.

Ralstonia solanacearum elicitor RipX Induces Defense Reaction by Suppressing the Mitochondrial atpA Gene in Host Plant. (Mus musculus) PubMed

 26321.

Overexpression of the response regulator rpaA causes an impaired cell division in the Cyanobacterium Synechocystis sp. PCC 6803. (Mus musculus) PubMed

 26322.

Chlamydia psittaci PmpD-N Exacerbated Chicken Macrophage Function by Triggering Th2 Polarization and the TLR2/MyD88/NF-kappaB Signaling Pathway. (Mus musculus) PubMed

 26323.

Overexpression of wheat alpha-mannosidase gene TaMP impairs salt tolerance in transgenic Brachypodium distachyon. (Mus musculus) PubMed

 26324.

The barley stripe mosaic virus expression system reveals the wheat C2H2 zinc finger protein TaZFP1B as a key regulator of drought tolerance. (Mus musculus) PubMed

 26325.

Formation of pre-pore complexes of pneumolysin is accompanied by a decrease in short-range order of lipid molecules throughout vesicle bilayers. (Mus musculus) PubMed

 26326.

Effects of Osiris9a on Silk Properties in Bombyx mori Determined by Transgenic Overexpression. (Mus musculus) PubMed

 26327.

Polymorphism and natural selection in the merozoite surface protein 3F2 (PVX_97710) locus of Plasmodium vivax among field isolates. (Mus musculus) PubMed

 26328.

Stress aggravates and prolongs imiquimod-induced psoriasis-like epidermal hyperplasis and IL-1beta/IL-23p40 production. (Mus musculus) PubMed

 26329.

LncRNAMORT is upregulated in myocardial infarction and promotes the apoptosis of cardiomyocyte by downregulating miR-93. (Mus musculus) PubMed

 26330.

Crystal structure of Type IX secretion system PorE C-terminal domain from Porphyromonas gingivalis in complex with a peptidoglycan fragment. (Mus musculus) PubMed

 26331.

Antibodies against a short region of PfRipr inhibit Plasmodium falciparum merozoite invasion and PfRipr interaction with Rh5 and SEMA7A. (Mus musculus) PubMed

 26332.

Molecular movie of nucleotide binding to a motor protein. (Mus musculus) PubMed

 26333.

TNPO3-Mediated Nuclear Entry of the Rous Sarcoma Virus Gag Protein Is Independent of the Cargo-Binding Domain. (Mus musculus) PubMed

 26334.

Mitochondrial Import of Dengue Virus NS3 Protease and Cleavage of GrpEL1, a Cochaperone of Mitochondrial Hsp70. (Mus musculus) PubMed

 26335.

Enzymatic versatility and thermostability of a new aryl-alcohol oxidase from Thermothelomyces thermophilus M77. (Mus musculus) PubMed

 26336.

ErpA is important but not essential for the Fe/S cluster biogenesis of Escherichia coli NADH:ubiquinone oxidoreductase (complex I). (Mus musculus) PubMed

 26337.

Impact of solid surface hydrophobicity and micrococcal nuclease production on Staphylococcus aureus Newman biofilms. (Mus musculus) PubMed

 26338.

NfoR: Chromate Reductase or Flavin Mononucleotide Reductase? (Mus musculus) PubMed

 26339.

NisI Maturation and Its Influence on Nisin Resistance in Lactococcus lactis. (Mus musculus) PubMed

 26340.

Mycobacterium tuberculosis Rv1096, facilitates mycobacterial survival by modulating the NF-kappaB/MAPK pathway as peptidoglycan N-deacetylase. (Mus musculus) PubMed

 26341.

Improving Arsenic Tolerance of Pyrococcus furiosus by Heterologous Expression of a Respiratory Arsenate Reductase. (Mus musculus) PubMed

 26342.

Outer Membrane c-Type Cytochromes OmcA and MtrC Play Distinct Roles in Enhancing the Attachment of Shewanella oneidensis MR-1 Cells to Goethite. (Mus musculus) PubMed

 26343.

Engineering Burkholderia xenovorans LB400 BphA through Site-Directed Mutagenesis at Position 283. (Mus musculus) PubMed

 26344.

Semaphorin-1a-like gene plays an important role in the embryonic development of silkworm, Bombyx mori. (Mus musculus) PubMed

 26345.

Trehalose Degradation by Cellvibrio japonicus Exhibits No Functional Redundancy and Is Solely Dependent on the Tre37A Enzyme. (Mus musculus) PubMed

 26346.

The Syringate O-Demethylase Gene of Sphingobium sp. Strain SYK-6 Is Regulated by DesX, while Other Vanillate and Syringate Catabolism Genes Are Regulated by DesR. (Mus musculus) PubMed

 26347.

OnfD, an AraC-Type Transcriptional Regulator Encoded by Rhizobium tropici CIAT 899 and Involved in Nod Factor Synthesis and Symbiosis. (Mus musculus) PubMed

 26348.

Large yellow croaker peroxiredoxin IV protect cells against oxidative damage and apoptosis. (Mus musculus) PubMed

 26349.

NADH dehydrogenases Nuo and Nqr1 contribute to extracellular electron transfer by Shewanella oneidensis MR-1 in bioelectrochemical systems. (Mus musculus) PubMed

 26350.

Cytosolic GABA inhibits anion transport by wheat ALMT1. (Mus musculus) PubMed

 26351.

CD38 play roles in T cell-dependent response and B cell differentiation in nile tilapia (Oreochromis niloticus). (Mus musculus) PubMed

 26352.

The putative transcriptional regulator STM14_3563 facilitates Salmonella Typhimurium pathogenicity by activating virulence-related genes. (Mus musculus) PubMed

 26353.

Identification of a gene regulated by HetR, a master regulator of heterocyst differentiation, in the non-heterocyst-forming filamentous cyanobacterium Arthrospira platensis NIES-39. (Mus musculus) PubMed

 26354.

Fine mapping of Brassica napus blackleg resistance gene Rlm1 through bulked segregant RNA sequencing. (Mus musculus) PubMed

 26355.

Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration. (Mus musculus) PubMed

 26356.

Crystal structure of alpha-glucosyl transfer enzyme XgtA from Xanthomonas campestris WU-9701. (Mus musculus) PubMed

 26357.

Pic-Producing Escherichia coli Induces High Production of Proinflammatory Mediators by the Host Leading to Death by Sepsis. (Mus musculus) PubMed

 26358.

Characterization of a Phosphatidylserine Synthase of Vibrio parahaemolyticus. (Mus musculus) PubMed

 26359.

Identification and analysis of a principal sigma factor interacting protein SinA, essential for growth at high temperatures in a cyanobacterium Synechococcus elongatus PCC 7942. (Mus musculus) PubMed

 26360.

The Rice Basic Helix-Loop-Helix 79 (OsbHLH079) Determines Leaf Angle and Grain Shape. (Mus musculus) PubMed

 26361.

Wheat gene Sr60 encodes a protein with two putative kinase domains that confers resistance to stem rust. (Mus musculus) PubMed

 26362.

Antagonistic action of TILLERS ABSENT1 and FLORAL ORGAN NUMBER2 regulates stem cell maintenance during axillary meristem development in rice. (Mus musculus) PubMed

 26363.

Defective Pollen Wall 3 (DPW3), a novel alpha integrin-like protein, is required for pollen wall formation in rice. (Mus musculus) PubMed

 26364.

Differential effects of 'resurrecting' Csp pseudoproteases during Clostridioides difficile spore germination. (Mus musculus) PubMed

 26365.

A novel multidomain acyl-CoA carboxylase in Saccharopolyspora erythraea provides malonyl-CoA for de novo fatty acid biosynthesis. (Mus musculus) PubMed

 26366.

Alcohol dehydrogenase 5 of Helicoverpa armigera interacts with the CYP6B6 promoter in response to 2-tridecanone. (Mus musculus) PubMed

 26367.

Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus. (Mus musculus) PubMed

 26368.

Decoding allosteric communication pathways in protein lysine acetyltransferase. (Mus musculus) PubMed

 26369.

The Mean Staple Length of Wool Fibre Is Associated with Variation in the Ovine Keratin-Associated Protein 21-2 Gene. (Mus musculus) PubMed

 26370.

Comparing the Conformational Stability of Pyruvate Kinase in the Gas Phase and in Solution. (Mus musculus) PubMed

 26371.

The Phosphatase PP1 Promotes Mitotic Slippage through Mad3 Dephosphorylation. (Mus musculus) PubMed

 26372.

The Caenorhabditis elegans INX-4/Innexin is required for the fine-tuning of temperature orientation in thermotaxis behavior. (Mus musculus) PubMed

 26373.

M. leprae HSP18 suppresses copper (II) mediated ROS generation: Effect of redox stress on its structure and function. (Mus musculus) PubMed

 26374.

The Saltol QTL-localized transcription factor OsGATA8 plays an important role in stress tolerance and seed development in Arabidopsis and rice. (Mus musculus) PubMed

 26375.

Two forms of NAD-malic enzyme in maize leaves are regulated by light in opposite ways via promoter methylation. (Mus musculus) PubMed

 26376.

Borrelia burgdorferi spatiotemporal regulation of transcriptional regulator bosR and decorin binding protein during murine infection. (Mus musculus) PubMed

 26377.

Biotin Synthesis in Ralstonia eutropha H16 Utilizes Pimeloyl Coenzyme A and Can Be Regulated by the Amount of Acceptor Protein. (Mus musculus) PubMed

 26378.

Flavin Adenine Dinucleotide-Dependent Halogenase XanH and Engineering of Multifunctional Fusion Halogenases. (Mus musculus) PubMed

 26379.

Species-Specific Quorum Sensing Represses the Chitobiose Utilization Locus in Vibrio cholerae. (Mus musculus) PubMed

 26380.

SufR, a [4Fe-4S] Cluster-Containing Transcription Factor, Represses the sufRBDCSU Operon in Streptomyces avermitilis Iron-Sulfur Cluster Assembly. (Mus musculus) PubMed

 26381.

PfMAP-2 is essential for male gametogenesis in the malaria parasite Plasmodium falciparum. (Mus musculus) PubMed

 26382.

Rhizobium leguminosarum bv. trifolii NodD2 Enhances Competitive Nodule Colonization in the Clover-Rhizobium Symbiosis. (Mus musculus) PubMed

 26383.

Flavin Adenine Dinucleotide-Dependent Halogenase XanH and Engineering of Multifunctional Fusion Halogenases. (Mus musculus) PubMed

 26384.

Enterococcus faecalis Maltodextrin Gene Regulation by Combined Action of Maltose Gene Regulator MalR and Pleiotropic Regulator CcpA. (Mus musculus) PubMed

 26385.

Mapping N- and C-terminals of Leishmania donovani tyrosine aminotransferase by gene truncation strategy: a functional study using in vitro and in silico approaches. (Mus musculus) PubMed

 26386.

The polyketide synthase PKS15 has a crucial role in cell wall formation in Beauveria bassiana. (Mus musculus) PubMed

 26387.

Molecular evidence for the involvement of cotton GhGLP2, in enhanced resistance to Verticillium and Fusarium Wilts and oxidative stress. (Mus musculus) PubMed

 26388.

Modulation of non-bilayer lipid phases and the structure and functions of thylakoid membranes: effects on the water-soluble enzyme violaxanthin de-epoxidase. (Mus musculus) PubMed

 26389.

Functional characterization of three Azotobacter chroococcum alginate-modifying enzymes related to the Azotobacter vinelandii AlgE mannuronan C-5-epimerase family. (Mus musculus) PubMed

 26390.

Rab35-GEFs, DENND1A and folliculin differentially regulate podocalyxin trafficking in two- and three-dimensional epithelial cell cultures. (Mus musculus) PubMed

 26391.

Pseudomonas aeruginosa exoenzyme Y directly bundles actin filaments. (Mus musculus) PubMed

 26392.

Functional analysis of Clostridium difficile sortase B reveals key residues for catalytic activity and substrate specificity. (Mus musculus) PubMed

 26393.

Methionine sulfoxide reductase B from Corynebacterium diphtheriae catalyzes sulfoxide reduction via an intramolecular disulfide cascade. (Mus musculus) PubMed

 26394.

A plant pentatricopeptide repeat protein with a DYW-deaminase domain is sufficient for catalyzing C-to-U RNA editing in vitro. (Mus musculus) PubMed

 26395.

Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation. (Mus musculus) PubMed

 26396.

Identification of the WUSCHEL-Related Homeobox (WOX) Gene Family, and Interaction and Functional Analysis of TaWOX9 and TaWUS in Wheat. (Mus musculus) PubMed

 26397.

A role for the OsHKT 2;1 sodium transporter in potassium use efficiency in rice. (Mus musculus) PubMed

 26398.

SulA is able to block cell division in Escherichia coli by a mechanism different from sequestration. (Mus musculus) PubMed

 26399.

Mitogen-activated protein kinase regulation of the phosphodiesterase RegA in early Dictyostelium development. (Mus musculus) PubMed

 26400.

Crystal structure of Gig2 protein from Candida albicans provides a structural insight into DUF1479 family oxygenases. (Mus musculus) PubMed

 26401.

Bacterial rhomboid proteases mediate quality control of orphan membrane proteins. (Mus musculus) PubMed

 26402.

Precancerous Gastric Lesions with Helicobacter pylori vacA (+)/babA2(+)/oipA (+) Genotype Increase the Risk of Gastric Cancer. (Mus musculus) PubMed

 26403.

Methylglyoxal inhibits nuclear division through alterations in vacuolar morphology and accumulation of Atg18 on the vacuolar membrane in Saccharomyces cerevisiae. (Mus musculus) PubMed

 26404.

Impact on Multiple Antibiotic Pathways Reveals MtrA as a Master Regulator of Antibiotic Production in Streptomyces spp. and Potentially in Other Actinobacteria. (Mus musculus) PubMed

 26405.

Novel Biochemical Properties and Physiological Role of the Flavin Mononucleotide Oxidoreductase YhdA from Bacillus subtilis. (Mus musculus) PubMed

 26406.

Impact on Multiple Antibiotic Pathways Reveals MtrA as a Master Regulator of Antibiotic Production in Streptomyces spp. and Potentially in Other Actinobacteria. (Mus musculus) PubMed

 26407.

A Novel Two-Component System, XygS/XygR, Positively Regulates Xyloglucan Degradation, Import, and Catabolism in Ruminiclostridium cellulolyticum. (Mus musculus) PubMed

 26408.

Deletion of a Peptidylprolyl Isomerase Gene Results in the Inability of Caldicellulosiruptor bescii To Grow on Crystalline Cellulose without Affecting Protein Glycosylation or Growth on Soluble Substrates. (Mus musculus) PubMed

 26409.

Impact on Multiple Antibiotic Pathways Reveals MtrA as a Master Regulator of Antibiotic Production in Streptomyces spp. and Potentially in Other Actinobacteria. (Mus musculus) PubMed

 26410.

A central role for the transcriptional regulator VtlR in small RNA-mediated gene regulation in Agrobacterium tumefaciens. (Mus musculus) PubMed

 26411.

Kinetic solvent viscosity effects reveal a protein isomerization in the reductive half-reaction of Neurospora crassa class II nitronate monooxygenase. (Mus musculus) PubMed

 26412.

Defects in the rice aconitase-encoding OsACO1 gene alter iron homeostasis. (Mus musculus) PubMed

 26413.

Velvet activated McrA plays a key role in cellular and metabolic development in Aspergillus nidulans. (Mus musculus) PubMed

 26414.

Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments. (Mus musculus) PubMed

 26415.

Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif. (Mus musculus) PubMed

 26416.

Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages. (Mus musculus) PubMed

 26417.

Plasmodium translocon component EXP2 facilitates hepatocyte invasion. (Mus musculus) PubMed

 26418.

Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease. (Mus musculus) PubMed

 26419.

Characterization of two sugar transporters responsible for efficient xylose uptake in an oleaginous yeast Candida tropicalis SY005. (Mus musculus) PubMed

 26420.

Exploring the intrinsic dynamics of SARS-CoV-2, SARS-CoV and MERS-CoV spike glycoprotein through normal mode analysis using anisotropic network model. (Mus musculus) PubMed

 26421.

A highly active heparinase I from Bacteroides cellulosilyticus: Cloning, high level expression, and molecular characterization. (Mus musculus) PubMed

 26422.

Taken together, the findings of the current study indicate that Newcastle disease virus V protein interacts with CacyBP/SIP, thereby regulating cell apoptosis and viral replication.[V] (Mus musculus) PubMed

 26423.

Taken together, these data demonstrate that Newcastle disease virus infection and Newcastle disease virus nonstructural V protein activates the expression of SOCS3 at the mRNA and protein level through a mechanism dependent on the MEK/ERK signaling pathway, which benefits virus replication.[non-structural V protein] (Mus musculus) PubMed

 26424.

The replication abilities of strains with C-terminally deleted W proteins were lower than that of the parental strain.[W protein] (Mus musculus) PubMed

 26425.

A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts. (Mus musculus) PubMed

 26426.

Roles of Elm1 in antifungal susceptibility and virulence in Candida glabrata. (Mus musculus) PubMed

 26427.

Identification and functional analysis of five genes that encode distinct isoforms of protein phosphatase 1 in Nilaparvata lugens. (Mus musculus) PubMed

 26428.

ISGylation of Hepatitis C Virus NS5A Protein Promotes Viral RNA Replication via Recruitment of Cyclophilin A. (Mus musculus) PubMed

 26429.

MksB, an alternate condensin from Mycobacterium smegmatis is involved in DNA binding and condensation. (Mus musculus) PubMed

 26430.

Characterization of Self-Processing Activities and Substrate Specificities of Porcine Torovirus 3C-Like Protease. (Mus musculus) PubMed

 26431.

On the simultaneous activation of Agrobacterium tumefaciens ADP-glucose pyrophosphorylase by pyruvate and fructose 6-phosphate. (Mus musculus) PubMed

 26432.

Proton-coupled electron transfer mechanisms of the copper centres of nitrous oxide reductase from Marinobacter hydrocarbonoclasticus - An electrochemical study. (Mus musculus) PubMed

 26433.

Characterization of a novel bifunctional mannuronan C-5 epimerase and alginate lyase from Pseudomonas mendocina. sp. DICP-70. (Mus musculus) PubMed

 26434.

Structure-function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay. (Mus musculus) PubMed

 26435.

Structural basis for STAT2 suppression by flavivirus NS5. (Mus musculus) PubMed

 26436.

Structural basis for STAT2 suppression by flavivirus NS5. (Mus musculus) PubMed

 26437.

Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. (Mus musculus) PubMed

 26438.

Poxvirus-encoded TNF receptor homolog dampens inflammation and protects from uncontrolled lung pathology during respiratory infection. (Mus musculus) PubMed

 26439.

Effective refolding of a cysteine rich glycoside hydrolase family 19 recombinant chitinase from Streptomyces griseus by reverse dilution and affinity chromatography. (Mus musculus) PubMed

 26440.

A host target of a bacterial cysteine protease virulence effector plays a key role in convergent evolution of plant innate immune system receptors. (Mus musculus) PubMed

 26441.

DWT1/DWL2 act together with OsPIP5K1 to regulate plant uniform growth in rice. (Mus musculus) PubMed

 26442.

A transcription factor OsbHLH156 regulates Strategy II iron acquisition through localising IRO2 to the nucleus in rice. (Mus musculus) PubMed

 26443.

Two nuclear effectors of the rice blast fungus modulate host immunity via transcriptional reprogramming. (Mus musculus) PubMed

 26444.

Expression of ESAT-6 antigen from Mycobacterium tuberculosis in broccoli: An edible plant. (Mus musculus) PubMed

 26445.

Knockdown of CTRP6 reduces the deposition of intramuscular and subcutaneous fat in pigs via different signaling pathways. (Mus musculus) PubMed

 26446.

The secreted protein kinase CstK from Coxiella burnetii influences vacuole development and interacts with the GTPase-activating host protein TBC1D5. (Mus musculus) PubMed

 26447.

Local structural plasticity of the Staphylococcus aureus evasion protein EapH1 enables engagement with multiple neutrophil serine proteases. (Mus musculus) PubMed

 26448.

Enhancing the antigenicity and immunogenicity of monomeric forms of hepatitis C virus E2 for use as a preventive vaccine. (Mus musculus) PubMed

 26449.

Mycobacterium smegmatis MSMEG_0129 is a nutrition-associated regulator that interacts with CarD and ClpP2. (Mus musculus) PubMed

 26450.

Identification and functional characterization of a lipid droplet protein CtLDP1 from an oleaginous yeast Candida tropicalis SY005. (Mus musculus) PubMed

 26451.

The genome of a Bacteroidetes inhabitant of the human gut encodes a structurally distinct enoyl-acyl carrier protein reductase (FabI). (Mus musculus) PubMed

 26452.

Regulation of adiponectin on lipid metabolism in large yellow croaker (Larimichthys crocea). (Mus musculus) PubMed

 26453.

Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3. (Mus musculus) PubMed

 26454.

The Escherichia coli cellulose synthase subunit G (BcsG) is a Zn(2+)-dependent phosphoethanolamine transferase. (Mus musculus) PubMed

 26455.

Structural and mutational analyses of the bifunctional arginine dihydrolase and ornithine cyclodeaminase AgrE from the cyanobacterium Anabaena. (Mus musculus) PubMed

 26456.

Expression of an Extracellular Protein (SMU.63) Is Regulated by SprV in Streptococcus mutans. (Mus musculus) PubMed

 26457.

miR-142-5P regulates triglyceride by targeting CTNNB1 in goat mammary epithelial cells. (Mus musculus) PubMed

 26458.

Expression of an Extracellular Protein (SMU.63) Is Regulated by SprV in Streptococcus mutans. (Mus musculus) PubMed

 26459.

Transcriptome analysis reveals the regulation of the shrimp STAT on host chitin-binding domain containing proteins and energy metabolism process during WSSV infection. (Mus musculus) PubMed

 26460.

The kruppel-like factor of Penaeus vannamei negatively regulates transcription of the small subunit hemocyanin gene as part of shrimp immune response. (Mus musculus) PubMed

 26461.

Characterization of class B scavenger receptor type 1 (SRB1) in turbot (Scophthalmus maximus L.). (Mus musculus) PubMed

 26462.

Characterization of the inflammasome component SmASC in turbot (Scophthalmus maximus). (Mus musculus) PubMed

 26463.

Quantification of the affinities of CRISPR-Cas9 nucleases for cognate protospacer adjacent motif (PAM) sequences. (Mus musculus) PubMed

 26464.

Quantification of the affinities of CRISPR-Cas9 nucleases for cognate protospacer adjacent motif (PAM) sequences. (Mus musculus) PubMed

 26465.

MtrP, a putative methyltransferase in Corynebacteria, is required for optimal membrane transport of trehalose mycolates. (Mus musculus) PubMed

 26466.

A Legionella effector kinase is activated by host inositol hexakisphosphate. (Mus musculus) PubMed

 26467.

The single CCA-adding enzyme of T. brucei has distinct functions in the cytosol and in mitochondria. (Mus musculus) PubMed

 26468.

Roles of active-site residues in catalysis, substrate binding, cooperativity, and the reaction mechanism of the quinoprotein glycine oxidase. (Mus musculus) PubMed

 26469.

Modeling of variables in cellular infection reveals CXCL10 levels are regulated by human genetic variation and the Chlamydia-encoded CPAF protease. (Mus musculus) PubMed

 26470.

Cyclic-di-GMP Regulates the Quorum-Sensing System and Biocontrol Activity of Pseudomonas fluorescens 2P24 through the RsmA and RsmE Proteins. (Mus musculus) PubMed

 26471.

Characterization of alkylguaiacol-degrading cytochromes P450 for the biocatalytic valorization of lignin. (Mus musculus) PubMed

 26472.

Characterization of alkylguaiacol-degrading cytochromes P450 for the biocatalytic valorization of lignin. (Mus musculus) PubMed

 26473.

Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography. (Mus musculus) PubMed

 26474.

Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein. (Mus musculus) PubMed

 26475.

Ensemble Docking Coupled to Linear Interaction Energy Calculations for Identification of Coronavirus Main Protease (3CL(pro)) Non-Covalent Small-Molecule Inhibitors. (Mus musculus) PubMed

 26476.

Molecular Docking Study on Several Benzoic Acid Derivatives against SARS-CoV-2. (Mus musculus) PubMed

 26477.

Multilayered Regulation of Membrane-Bound ONAC054 Is Essential for Abscisic Acid-Induced Leaf Senescence in Rice. (Mus musculus) PubMed

 26478.

PROTEIN PHOSPHATASE95 Regulates Phosphate Homeostasis by Affecting Phosphate Transporter Trafficking in Rice. (Mus musculus) PubMed

 26479.

GPA5 Encodes a Rab5a Effector Required for Post-Golgi Trafficking of Rice Storage Proteins. (Mus musculus) PubMed

 26480.

Design of a Repellent Against Aedes aegypti (Diptera: Culicidae) Using in silico Simulations With AaegOBP1 Protein. (Mus musculus) PubMed

 26481.

VdOGDH is involved in energy metabolism and required for virulence of Verticillium dahliae. (Mus musculus) PubMed

 26482.

Kruppel homologue 1 interacts directly with Hairy and regulates ecdysis in the brown planthopper. (Mus musculus) PubMed

 26483.

Circ_016719 plays a critical role in neuron cell apoptosis induced by I/R via targeting miR-29c/Map2k6. (Mus musculus) PubMed

 26484.

Leptospira interrogans Bat proteins impair host hemostasis by fibrinogen cleavage and platelet aggregation inhibition. (Mus musculus) PubMed

 26485.

Mitochondrial FgEch1 is responsible for conidiation and full virulence in Fusarium graminearum. (Mus musculus) PubMed

 26486.

Redox potential change by the cystine importer affected on enzymatic antioxidant protection in Deinococcus geothermalis. (Mus musculus) PubMed

 26487.

Quantitative Imaging Reveals Distinct Contributions of SnRK2 and ABI3 in Plasmodesmatal Permeability in Physcomitrella patens. (Mus musculus) PubMed

 26488.

The P5-type ATPase Spf1 is required for development and virulence of the rice blast fungus Pyricularia oryzae. (Mus musculus) PubMed

 26489.

The cyanobacterial phytochrome 2 regulates the expression of motility-related genes through the second messenger cyclic di-GMP. (Mus musculus) PubMed

 26490.

OsMYB80 Regulates Anther Development and Pollen Fertility by Targeting Multiple Biological Pathways. (Mus musculus) PubMed

 26491.

Surveillance of a kdr Resistance Mutation in Culex pipiens (Diptera: Culicidae) and Culex quinquefasciatus in California. (Mus musculus) PubMed

 26492.

Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus. (Mus musculus) PubMed

 26493.

Nonstructural protein 6 of porcine epidemic diarrhea virus induces autophagy to promote viral replication via the PI3K/Akt/mTOR axis. (Mus musculus) PubMed

 26494.

Raffinose synthase enhances drought tolerance through raffinose synthesis or galactinol hydrolysis in maize and Arabidopsis plants. (Mus musculus) PubMed

 26495.

Role of a 21-kDa iron-regulated protein IrpA in the uptake of ferri-exochelin by Mycobacterium smegmatis. (Mus musculus) PubMed

 26496.

3CL hydrolase-based multiepitope peptide vaccine against SARS-CoV-2 using immunoinformatics. (Mus musculus) PubMed

 26497.

Long-term exercise-secreted extracellular vesicles promote browning of white adipocytes by suppressing miR-191a-5p. (Mus musculus) PubMed

 26498.

Hcp2a of type VI secretion system contributes to IL8 and IL1beta expression of chicken tracheal epithelium by affecting APEC colonization. (Mus musculus) PubMed

 26499.

Enzymatic reaction mechanism of cis-aconitate decarboxylase based on the crystal structure of IRG1 from Bacillus subtilis. (Mus musculus) PubMed

 26500.

Mosquito Defensins Enhance Japanese Encephalitis Virus Infection by Facilitating Virus Adsorption and Entry within the Mosquito. (Mus musculus) PubMed

 26501.

M-like protein SrM is not crucial to the virulence of a novel isolate of Streptococcus equi subsp. ruminatorum from Macaca mulatta. (Mus musculus) PubMed

 26502.

A new functional JAZ degron sequence in strawberry JAZ1 revealed by structural and interaction studies on the COI1-JA-Ile/COR-JAZs complexes. (Mus musculus) PubMed

 26503.

Orsay Virus CP-delta Adopts a Novel beta-Bracelet Structural Fold and Incorporates into Virions as a Head Fiber. (Mus musculus) PubMed

 26504.

Vitamin B12 may inhibit RNA-dependent-RNA polymerase activity of nsp12 from the SARS-CoV-2 virus. (Mus musculus) PubMed

 26505.

A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation. (Mus musculus) PubMed

 26506.

Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease. (Mus musculus) PubMed

 26507.

The HK5 and HK6 cytokinin receptors mediate diverse developmental pathways in rice. (Mus musculus) PubMed

 26508.

RTI(40)/MMC4/RTII(70)- and RTI(40)/MMC4-positive cells are intermediates in the ATII-to-ATI cell transformation. (MMC4 antigen, RTII70) (Rattus norvegicus) PubMed

 26509.

[Brain-pancreas relative protein, BPRP] Stressed rats showed a significant reduction in pancreatic BPRP, which was accompanied by an increase in levels of blood sugar and a decrease of insulin. No apparent alteration in hippocampal BPRP was noted. (Rattus norvegicus) PubMed

 26510.

Ovulation induction in rats resulted in increased Ki67 expression and dysplastic features in the ovarian epithelial cells[Ki67] (Rattus norvegicus) PubMed

 26511.

Testosterone specifically controls DcR2 expression in the adult rat ventral prostate. Androgen withdrawal, by reducing DcR2 expression, might leave the cells vulnerable to cell death signals generated by TRAIL via its functional receptors.[DcR2/TRAIL-R4] (Rattus norvegicus) PubMed

 26512.

Suggest that brain-pancreas relative protein (BPRP) and calpain activity may contribute to diabetes complications in the central nervous system. (Rattus norvegicus) PubMed

 26513.

Co-expression of two of the other subunits of the protein complex together with PRO1/PRO2 abrogated the cytotoxic effect without altering PRO1/PRO2 protein levels[PRO1/PRO2 ] (Rattus norvegicus) PubMed

 26514.

Baseline regulation of hexose transporter (SGLT1, GLUT2, and GLUT5) function is not mediated tonically by intrinsic or extrinsic neural continuity to the jejunoileum [GLUT5]. (Rattus norvegicus) PubMed

 26515.

Crgn1 and Crgn2 contribute exclusively to circulating cell-related glomerular injury by regulating macrophage infiltration and activation [Crgn1 and Crgn2]. (Rattus norvegicus) PubMed

 26516.

an unknown epitope of an antigen in rat kidney papilla termed renal papillary antigen 1 (RPA-1)is an excellent marker of renal papillary necrosis (Rattus norvegicus) PubMed

 26517.

PC-PLC is involved in cell-cycle regulation, proliferation, and apoptosis in CBRH-7919 cells. (Rattus norvegicus) PubMed

 26518.

Data suggest that Idh3alpha plays a role in neuronal differentiation [Idh3alpha]. (Rattus norvegicus) PubMed

 26519.

a key role for AKAP-targeted PKA in control of heart rate and contractile function [PKA RII alpha] (Rattus norvegicus) PubMed

 26520.

identified and cloned a new gene, GON-SJTU1; GON-SJTU1 may play a role in the biological process of spermatogenesis [GON-SJTU1] (Rattus norvegicus) PubMed

 26521.

Results suggest that protocadherin-gammaC5 (Pcdh-gammaC5) plays a role in synaptic specificity and/or synaptic maturation, and is involved in neuron-neuron synaptic interactions and in neuron-astrocyte interactions [Pcdh-gammaC5]. (Rattus norvegicus) PubMed

 26522.

the expression, cellular localization and coupling to membrane signalling (inositol phosphate accumulation) of alpha(1)-adrenoceptor subtypes in a native tissue [alpha 1L-adrenoceptor] (Rattus norvegicus) PubMed

 26523.

Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury. (Rattus norvegicus) PubMed

 26524.

This study demonstrated that miR-155 could have an important role in regulating adventitial fibroblast differentiation and contribute to suppression of AT(1)R expression. (Rattus norvegicus) PubMed

 26525.

Concentrations of Casp3 and IL8 increased significantly on days 4, 7 and 14 postexposure in the lungs of preterm rats exposed to hyperoxia. (Rattus norvegicus) PubMed

 26526.

In the adult offspring, placental malnutrition programmed: decrease in Na-ATPase activity and loss of the physiological stimulation of this pump by angiotensin II. [Na-ATPase] (Rattus norvegicus) PubMed

 26527.

H(2)O(2)-mediated up-regulation of Mipu1 protein expression was abrogated by the suppression of CREB expression with small interfering RNA of CREB. (Rattus norvegicus) PubMed

 26528.

These results suggest that GSK-3beta phosphorylation at the time of reperfusion by a PKC-epsilon, PI3K- and A2b receptor-dependent mechanism contributes to prevention of myocardial necrosis by pre-ischemic activation of the mK(ATP) channel.[mK(ATP) (Rattus norvegicus) PubMed

 26529.

This is the first report which shows the involvement of PKC epsilon, DGK eta, Tnfaip, and Rho kinase in the liver of type 2 diabetic rats and its association with diabetic nephropathy.[DGK eta, Tnfaip] (Rattus norvegicus) PubMed

 26530.

TRbeta1, NCoR-1, and the recently identified DOR/TP53INP2 are abundantly expressed and down-regulated in liver cells during APR. (Rattus norvegicus) PubMed

 26531.

molar root patterning gene 1 may have a important function in the rat tooth root development. [molar root patterning gene 1] (Rattus norvegicus) PubMed

 26532.

Manipulation of the individual Rho GTPases showed differential effects on survival, with little variation in their migratory route and predominant differentiation into the oligodendroglial lineage.[Rac, Rho] (Rattus norvegicus) PubMed

 26533.

The role of KLF6 and PPAR-gamma in MIP-3alpha transcriptional regulation, was determined.[MIP-3alpha] (Rattus norvegicus) PubMed

 26534.

beta-tubulin is one of downstream effectors of H89-sensitive kinase and suppression of endoplasmic reticulum (ER)-coupled beta-tubulin phosphorylation decreases Sar1 translocation onto the ER.[beta tubulin] (Rattus norvegicus) PubMed

 26535.

A novel neuronal signaling pathway is described whereby corticotropin-releasing factor leads to a rapid Gbetagamma- and MEK-dependent increase in CREB phosphorylation.[Gbeta, Ggamma] (Rattus norvegicus) PubMed

 26536.

MEKK1 probably activates a transcriptional partner of c-Jun whose activity is maintained or increased in the presence of the rat cholecystokinin 1 receptor but repressed in the presence of the mouse cholecystokinin 1 receptor.[CCK-R type 1] (Rattus norvegicus) PubMed

 26537.

Evidence supports that a single protein sustains both FMN cyclase and ATP-dependent Dha kinase activities, probably in a single active center (Rattus norvegicus) PubMed

 26538.

These results demonstrate that PGC-1beta is a coactivator in the T3 induction of CPT-Ialpha and that PGC-1beta has similarities and differences with the PGC-1alpha isoform. (Rattus norvegicus) PubMed

 26539.

Enzyme inhibition may provide a novel therapeutic strategy for diabetics during acute myocardial infarction, whereas morphine is less effective due to signaling events that adversely affect glycogen synthase kinase-3beta. (Rattus norvegicus) PubMed

 26540.

anti-atherogenic function of AKR1C15 through the protection of endothelial cells from damage elicited by toxic lipids such as HNE (Rattus norvegicus) PubMed

 26541.

These findings suggest that loss of function or decrease of RAR-beta2, RASSF1A, and CDKN2A, as well as the hypermethylation of 5' region of these genes, are related with nickel exposure.[RAR-beta2] (Rattus norvegicus) PubMed

 26542.

Truncated species, lacking the LIM-type domain, retains the dimeric structure of the wild-type protein but exhibits a 10-fold increased k(cat), a 3-fold decreased K(m) value for agmatine. [agmatinase-like protein] (Rattus norvegicus) PubMed

 26543.

a previously unrecognized function of miR-21 that is the reciprocal regulation of PTEN levels and Akt/TORC1 activity that mediate critical pathologic features of diabetic kidney disease (Rattus norvegicus) PubMed

 26544.

Results suggest that GOLACs 1 and 2 play dual roles in the Golgi complex, providing pathways for Cl(-) and ATP influx into the Golgi lumen. (Rattus norvegicus) PubMed

 26545.

Knockdown of ASIC2a subunit aggravates injury of rat C6 glioma cells in acidosis (Rattus norvegicus) PubMed

 26546.

NKT cells contribute to production of IL-17 mediated by IL-23 on a rat acute allograft rejection model of orthotopic liver transplantation [interleukin-23] (Rattus norvegicus) PubMed

 26547.

Depletion of glutathione was prime factor for initiating galactose cataract in rat. This depletion may in turn result in enzyme inactivation leading to cross-linking of protein and glycation. (glutathione) (Rattus norvegicus) PubMed

 26548.

(neuromelanin) Extracellular neuromelanin activated microglia and induced dopaminergic neurodegeneration. (Rattus norvegicus) PubMed

 26549.

A main novel function of telethonin is to modulate the turnover of the proapoptotic tumor suppressor p53 after biomechanical stress in the nuclear compartment, thus linking telethonin directly to apoptosis. (Rattus norvegicus) PubMed

 26550.

(REG-2; regeneration gene protein 2) Reg-2 might promote functional recovery by increasing axonal growth, inhibiting neuronal apoptosis, and attenuating spinal cord secondary injury. (Rattus norvegicus) PubMed

 26551.

Allergen may affect the systemic immunity to inhibit the RORgammat expression and block the Th17 differentiation in allergic rhinitis. [RORgammaT] (Rattus norvegicus) PubMed

 26552.

response of secretory pathways Ca(2+) ATPase gene expression to hyperhomocysteinemia and/or ischemic preconditioning (Rattus norvegicus) PubMed

 26553.

Plg-R(KT) was highly expressed in bovine adrenomedullary chromaffin cells, human pheochromocytoma tissue, PC12 pheochromocytoma cells, and murine hippocampus.[Plg-R(KT)] (Rattus norvegicus) PubMed

 26554.

Glycosylation of the CH2/CH3 interface inhibits interaction with the pathogen IgA binding protein SSL7, while maintaining binding of pIgR, essential to the biosynthesis and transport of SIgA.[FcalphaRI] (Rattus norvegicus) PubMed

 26555.

(Dopamine D2L receptor) These results found that the third cytoplasmic loop of dopamine D2L receptors adopt unique conformations and the insert region is not the basis for differences in signaling in dopamine recptor subtypes. (Rattus norvegicus) PubMed

 26556.

The expression of CPG15 mRNA in monocular form deprived development rats was obviously lower than in the normal group. (Rattus norvegicus) PubMed

 26557.

Central role for versican and its constituent chondroitin sulfate chains in controlling cell phenotype, elastogenesis, and intimal structure. (Rattus norvegicus) PubMed

 26558.

Inhibition of IKKbeta prevents free fatty acid(FFA)-induced impairment of hepatic insulin signaling, thus implicating IKKbeta as a causal mediator of hepatic insulin resistance caused by acutely elevated plasma FFA. (Rattus norvegicus) PubMed

 26559.

These data indicate that oxygen and glucose-deprivation culture decreases the expression of BPRP via enhanced formation of intracellular reactive oxygen species.[BPRP] (Rattus norvegicus) PubMed

 26560.

INGAP and/or related group 3 Reg proteins have a conserved expression in the pancreatic islet.[INGAP] (Rattus norvegicus) PubMed

 26561.

Timp-1, MMP-2, MMP-9, procollagen-n-proteinase, and col1a1 were all increased in spontaneously hypertensive rats [procollagen-n-peptidase and col1a1]. (Rattus norvegicus) PubMed

 26562.

This study demonstrates for the first time an endogenous small RNA that resembles an ancestral tRNA and exhibits some tRNA-like properties in mammals.(tpl-sRNA) (Rattus norvegicus) PubMed

 26563.

Myocyte gamma(3) gene expression is regulated by myocyte-specific M-CAT and MEF-1 elements.[MEF-1 factor] (Rattus norvegicus) PubMed

 26564.

The results indicate that in the presence of non-histone protein LMG160, in vitro RNA synthesis represses in the both systems, which can suggest a functional role for this non-histone chromosomal protein.[lmg160] (Rattus norvegicus) PubMed

 26565.

Serum levels of S100P are associated with acute coronary syndrome, and serum levels and myocardial expression of these proteins are related to infarct size. (Rattus norvegicus) PubMed

 26566.

Calcium, p38 MAPK activation and HIF-1alpha are necessary for low oxygen and glucose deprivation -reduced BPRP expression in PC12 cells.[BPRP] (Rattus norvegicus) PubMed

 26567.

NADPH-CoQ reductase located in cytosol may be the main enzyme responsible for the reduction of non-mitochondrial CoQ in cells[NADPH-dependent CoQ reductase] (Rattus norvegicus) PubMed

 26568.

The data indicate that the enzyme is a new type of NAP found in rodent. Its possible function in neuron growth, neurodegeneration, and carcinomas is discussed.(NAP-2) (Rattus norvegicus) PubMed

 26569.

study demonstrates that tuberalin II is a distinct secretory compound of the hypophyseal pars tuberalis [tuberalin II] (Rattus norvegicus) PubMed

 26570.

Activation of the cholinergic anti-inflammatory pathway can protect the lung against ventilator-induced lung injury by suppressing IL-8 and ICAM-1 expression. (Rattus norvegicus) PubMed

 26571.

Studied the DNA binding activity of human CDX2. Three CDX2-binding proteins were found in rat gastric tissue, and those proteins were identified to the homeobox protein Hox-D8, LIM homeobox protein 6, and SMC1L1 protein. [Hox-D8] (Rattus norvegicus) PubMed

 26572.

Suggest that calcineurin-mediated serine-637 dephosphorylation is involved in Drp1 activation during ATP depletion in renal tubular cells, leading to apoptosis. (Rattus norvegicus) PubMed

 26573.

The differential distribution patterns are consistent with complex roles for TORC1, -2, and -3 isoforms in diverse brain structures [TORC3]. (Rattus norvegicus) PubMed

 26574.

Sur8 is an antidifferentiation factor that stimulates proliferation for maintenance of self-renewal in NPCs via modulation of the Ras-ERK pathway. [Shoc2] (Rattus norvegicus) PubMed

 26575.

miR-124a mediates stroke-induced neurogenesis by targeting the JAG-Notch signaling pathway.[miR-124a] (Rattus norvegicus) PubMed

 26576.

(TIEG2)Transforming growth factor-beta-inducible early gene 2 was increased following ethanol administration in the prefrontal cortex. (Rattus norvegicus) PubMed

 26577.

DHEA: Prolonged DHEA exposure counteracted cortisol effects, restoring RACK-1 levels and cytokine production, as assessed by LPS-induced TNF-alpha release. (Rattus norvegicus) PubMed

 26578.

The expression of miRNA-146a was increased in LPS treated NR8383 alveolar macrophages. (Rattus norvegicus) PubMed

 26579.

Results report here a novel lysine-specific aminopeptidase (KAP) of ubiquitous distribution [KAP]. (Rattus norvegicus) PubMed

 26580.

Crystals of tripartite complex 1 of L27(PATJ)-(L27N,L27C)(Pals1)-L27(MALS) diffracted to 2.05 A resolution [PATJ] (Rattus norvegicus) PubMed

 26581.

Increased IL-8 (a proinflammatory cytokine) secretion and decreased IL-17 (a protective cytokine of airways) release can both contribute to development of chronic obstructive pulmonary disease.[Il-8] (Rattus norvegicus) PubMed

 26582.

CRF(1) agonists, Ucn 1 and stressin(1) -A, reduced feeding and induced interoceptive stress, whereas Ucn 2 potently suppressed feeding via a CRF(2) -dependent mechanism without eliciting malaise [stressin 1-a] (Rattus norvegicus) PubMed

 26583.

RhoA can aggravate the pathology changes of acute lung injury rats, which might be related to up regulating expression of IL-8 and down regulating expression of IL-10 by RhoA[interleukin 8] (Rattus norvegicus) PubMed

 26584.

Data suggest that interleukin-8 (IL-8) might be a potential therapeutic target in chronic radicular neuropathic pain: [IL-8] (Rattus norvegicus) PubMed

 26585.

TCGAP regulates neuronal morphogenesis in developing cortical neurons at both early and late stage in rats (Rattus norvegicus) PubMed

 26586.

NERP-3 in the hypothalamo-neurohypophyseal system may be involved in the regulation of body fluid balance [NERP-3] (Rattus norvegicus) PubMed

 26587.

The effects of arrestin 2 and 3 depletion on endothelin type A and P2Y2 receptor mediated ERK and p38 MAPK signaling, as well as migratory responses are reported. [arrestin 2] (Rattus norvegicus) PubMed

 26588.

[mPTP, mitochondrial permeability transition pore] Data from cell model of myocardial reperfusion injury suggest that production of reactive oxygen species (ROS) precedes mPTP opening; ROS produced during hypoxia are necessary to induce mPTP opening. (Rattus norvegicus) PubMed

 26589.

PP2A inhibits association between the Na+,K+-ATPase and arrestin, and diminishes the effect of arrestin on Na+,K+-ATPase trafficking.[Ppp2cc] (Rattus norvegicus) PubMed

 26590.

The role of cyclic adenosine monophosphate/protein kinase A (PKA) in the activation the ERK MAP kinase signaling system is reported.[PKA] (Rattus norvegicus) PubMed

 26591.

This differential expression pattern of lamin C in retinal neurons suggests that they may be involved in cellular differentiation and expression of cell-specific genes in individual retinal neurons.(larnin C) (Rattus norvegicus) PubMed

 26592.

study shows that NECC1 is a peripheral membrane protein displaying high stability to detergent extraction, which distributes across the Golgi apparatus in neuroendocrine cells[NECC1] (Rattus norvegicus) PubMed

 26593.

Clathrin expression and formation of clathrin-coated pits were critically required for endocytotic internalization of progastrin; in the absence of clathrin, progastrin failed to activate p38MAPK/ERKs.[progastrin] (Rattus norvegicus) PubMed

 26594.

Upregulation of miRNA-29 by HGF and downregulation by TGF-beta take part in the anti- or profibrogenic response of HSC, respectively [mirn29] (Rattus norvegicus) PubMed

 26595.

The results indicated that in vivo, retina glycogen may act as an immediately accessible energy reserve and that its content was controlled primarily by glucose-6-phosphate allosteric activation of glycogen synthase.[Glycogen synthase] (Rattus norvegicus) PubMed

 26596.

This result is the first to link Themis to the suppressive function of Treg and to suggest that, in Themis-deficient animals, defect of this function is involved in intestinal inflammation (Rattus norvegicus) PubMed

 26597.

NaV1.8 immunoreactivity was mostly found in small- and medium-diameter neurons together with PKCepsilon which phosphorylates it. NaV1.8. (Rattus norvegicus) PubMed

 26598.

Demonstrate a novel role for vascular peroxidase 1 (VPO1) in myocardium, mediating oxidative injury following myocardial ischemia reperfusion. (Rattus norvegicus) PubMed

 26599.

MiR-200a is involved in rat epididymal development by targeting beta-catenin mRNA [MiR-200a] (Rattus norvegicus) PubMed

 26600.

Intrathecally administered kappa-2 opioid receptor agonist GR89696 and IL-10 attenuated bone cancer-induced pain, and the 2 drugs interacted synergistically in the spinal cord. (Rattus norvegicus) PubMed

 26601.

M3 subtype of muscarinic acetylcholine receptor promotes cardioprotection via the suppression of miR-376b-5p [miR376] (Rattus norvegicus) PubMed

 26602.

results suggest that the PGE(2)-EP4-ERK pathway increases the number of osteo-adipogenic bipotential progenitor cells, with a resultant increase in adipogenesis in RC cell cultures. (Rattus norvegicus) PubMed

 26603.

decrease in responses to ATP in oocytes co-expressing different ratios of P2X1b to P2X1 was completely eliminated by overnight pretreatment with apyrase[P2X1b] (Rattus norvegicus) PubMed

 26604.

Paraquat may induce miR-133b expression, and cause cell damage and apoptosis in PC12 cells. (Rattus norvegicus) PubMed

 26605.

These results indicate that ATP8A2, acting in synergy with CDC50A, performs an important role in neurite outgrowth in neurons.[Atp8a2, CDC50A] (Rattus norvegicus) PubMed

 26606.

Maternal seizures reduced the number of neurons and also PSA-NCAM positive cells per unit area in the offspring hippocampus.[PSA-NCAM] (Rattus norvegicus) PubMed

 26607.

Abeta(25-35) decreases expression of BPRP. Salvianolic acid B, as anti-oxidant, protects against Abeta(25-35)-induced reduction in expression of BPRP through effects on suppressing production of ROS, Ca flux, & apoptosis[brain-pancreas relative protein] (Rattus norvegicus) PubMed

 26608.

These results suggest that Erbin is a negative feedback molecule induced by TGF-beta1 and inhibits TGF-beta1-induced epithelial-to-mesenchymal transition via ERK signaling pathway.[Erbin] (Rattus norvegicus) PubMed

 26609.

Normal developing myocardium and skeletal muscle transiently share both sk-fMHC and cTn-I proteins.[sk-FMHC] (Rattus norvegicus) PubMed

 26610.

Activation of NMII motor activity by light chain phosphorylation occurs at the cell edge and is uncoupled from NMII assembly into bipolar filaments.[NMII] (Rattus norvegicus) PubMed

 26611.

c-Ski is one of the newly found target genes of PPARgamma and thus involved in the anti-atherosclerotic effect of PPARgamma. [c-Ski] (Rattus norvegicus) PubMed

 26612.

Lysophosphatidic acid signals through LPA2 receptors and Galphaq proteins of cultured proximal tubule cells to transactivate latent TGF-beta in a Rho/Rho-kinase and alphavbeta6 integrin-dependent manner.[LPA2] (Rattus norvegicus) PubMed

 26613.

Results identify a novel molecule named multiple alpha-helix protein located at ER (Maxer) downregulated by mutant ataxin-1 (Atx1) in Bergmann glia. (Rattus norvegicus) PubMed

 26614.

TIGAR inhibits glycolysis in hypoxic myocytes and inhibition of glycolysis is closely involved in apoptosis, suggesting that TIGAR significantly mediates cellular energy homeostasis and cell death under ischemic stress. (Rattus norvegicus) PubMed

 26615.

Sig-1Rs negatively regulate the activity of GalCer synthesis under physiological conditions by enhancing the degradation of CGalT.[CGalT] (Rattus norvegicus) PubMed

 26616.

These results indicate for the first time that (P)RR triggers distinct Ang II-independent myocardial fibrosis and deterioration of cardiac function.[Prorenin receptor] (Rattus norvegicus) PubMed

 26617.

Agmatine can lower blood pressure in spontaneously hypertensive rats through activation of the peripheral imidazoline I(2) -receptor. (Rattus norvegicus) PubMed

 26618.

ANP modulates the mPTP opening by inactivating GSK-3beta through PKG and PI3K [mPTP] (Rattus norvegicus) PubMed

 26619.

PTG (protein targeting to glycogen) induction by glucose was MondoA dependent but ChREBP independent and was enhanced by forced elevation of fructose 2,6-bisphosphate and by additional xylitol-derived metabolites. [MondoA] (Rattus norvegicus) PubMed

 26620.

The conserved putative N-glycosylation site in K(2P)3.1 and K(2P)9.1 is a glycan acceptor site.[K2P3.1, K2P9.1] (Rattus norvegicus) PubMed

 26621.

Overexpression of miR-101a can mitigate interstitial fibrosis and the deterioration of cardiac performance in postinfarct rats, indicating the therapeutic potential of miR-101a for cardiac disease associated with fibrosis.[miR-101a] (Rattus norvegicus) PubMed

 26622.

leptin can enhance calcium-mediated, Stat3-dependent pro-apoptotic effects as a result of increased mitochondrial transition pore opening [mPTP] (Rattus norvegicus) PubMed

 26623.

Cytoprotective regulation of the mitochondrial permeability transition pore is impaired in type 2 diabetic Goto-Kakizaki rat hearts. (Rattus norvegicus) PubMed

 26624.

These results indicate a novel function of Nm23-H1 to control contact inhibition of locomotion, and its negative regulation by ephrin-B1.[Nm23-H1] (Rattus norvegicus) PubMed

 26625.

This study demonstrated the expression of the ghrelin receptor GHSR-1a in rat spermatids and epididymal spermatozoa, as well as some effects of ghrelin on the spermatozoa in vitro.[GHSR-1a] (Rattus norvegicus) PubMed

 26626.

Data suggest nickel-induced lung cancer is associated with NRG1 gene; NRG1 gene product is noncoding RNA; NRG-1 is within ADAMTS6 intron 2 and has high homology to LINE1 (long interspersed nucleotide element 1). [retrotransposon NRG1; HQ876091.1] (Rattus norvegicus) PubMed

 26627.

The similarity of nicotine and ABT-418 effects provides support for an alpha4beta2 nAChR mechanism of action for nicotine-induced improvement in attention/vigilance. (Rattus norvegicus) PubMed

 26628.

Phoenixin may represent a new class of hypothalamically-derived pituitary priming factors that sensitise the pituitary to the action of other releasing factors.[ Phoenixin, rat] (Rattus norvegicus) PubMed

 26629.

Urinary vitamin D binding protein: a potential novel marker of renal interstitial inflammation and fibrosis. (Rattus norvegicus) PubMed

 26630.

The DGKiota localizes to the synaptic area of bipolar cells in a punctate manner.(DGKiota,rat) (Rattus norvegicus) PubMed

 26631.

S-nitrosoglutathione reductase (GSNOR) inhibition preserves endothelial vasodilation under conditions of impaired NO production and protects against both microvascular and conduit artery dysfunction in a model of hypertension. (Rattus norvegicus) PubMed

 26632.

siRNA knockdown of Rab3Gap1 prevented plasma membrane Claudin-1 expression and the formation of a barrier competent epitheliumRAB3GAP1) (Rattus norvegicus) PubMed

 26633.

dietary obesity in the context of age-related insulin-insensitivity paradoxically improves myocardial I-R tolerance, in association with moderate hyperleptinaemic and enhanced RISK expression and phospho-regulation.[RISK] (Rattus norvegicus) PubMed

 26634.

The expression of genes involved in action potential generation and Ca(2+) homeostasis of cardiomyocytes in hypertensive cyp1a1ren-2 transgenic rats, was investigated.[renin 2] (Rattus norvegicus) PubMed

 26635.

Identify ephrin B4 (EphB4) signaling as a pathway allowing podocytes to survive transient capillary collapse during glomerular disease. (Rattus norvegicus) PubMed

 26636.

MMP-2 and -9 are involved in the translocation of MRTF-A in lens epithelial cellsduring TGFbeta-induced epithelial to mesenchymal transition.[MRTF-A] (Rattus norvegicus) PubMed

 26637.

The expression of LOTUS, LGI1, and ADAM22 in hippocampal subregions dissected from mature adult and aged rats cognitively phenotyped for spatial learning and memory by Morris water maze testing, was quantified.[LOTUS] (Rattus norvegicus) PubMed

 26638.

study reports a new native lncRNA - Kcna2 antisense RNA - that is expressed in DRG neurons; found Kcna2 antisense RNA may act as a biologically active regulator and participate in induction and maintenance of neuropathic pain by silencing Kcna2 expression in the DRG [Kcna2 antisense RNA] (Rattus norvegicus) PubMed

 26639.

Conclude that the cytoprotective effect of exogenously administered synthetic humanin is mediated by interactions of endogenous rat humanin with BAX in the cytoplasm during pro-apoptotic stress. (Rattus norvegicus) PubMed

 26640.

This study demonistrated that Axonal localization of neuritin/CPG15 mRNA in neuronal populations through distinct 5' and 3' UTR elements. (Rattus norvegicus) PubMed

 26641.

in rat spinal cord neurons, the immunoexpression of SMN and gemins 2 and 4 is present through the whole animal lifespan, are present in the same motoneurons and immunoexpression of gemin 2 and 4 decreases slightly with aging. (Rattus norvegicus) PubMed

 26642.

copine1 enhances neuronal differentiation of HiB5 cells not through the PI3K-Akt pathway, but by using another Akt activated signal pathway.(Copine1) (Rattus norvegicus) PubMed

 26643.

Suggest that miR-24/miR-29a pathway is involved in myocardin regulation of vascular response to injury. (Rattus norvegicus) PubMed

 26644.

In metabolic syndrome, serum salusin-alpha and salusin-beta levels were decreased; however, salusin levels/mg kidney tissue were elevated. (salusin-alpha and salusin-beta) (Rattus norvegicus) PubMed

 26645.

Elevated cpg15 expression in the frontal cortex suggests its possible involvement in regenerative and reparative processes that follow TBI. (Rattus norvegicus) PubMed

 26646.

Mover is associated with synaptic vesicles.[Mover] (Rattus norvegicus) PubMed

 26647.

AMPK is mediated in I2R activation for increase of glucose uptake in the skeletal muscle cell.[I2R] (Rattus norvegicus) PubMed

 26648.

Administration of a connexin mimetic peptide reduces secondary tissue damage after spinal cord injury by reducing gliosis and cytokine release. (Rattus norvegicus) PubMed

 26649.

These results suggest that altering gene expression for claudin5, TRPC4 and ZO1 by chlorpyrifos may directly contribute to blood-brain barrier disruption, and that the alteration is reversible upon removal of chlorpyrifos. [claudin5] (Rattus norvegicus) PubMed

 26650.

Green tea extract supplementation, and the tissue-specific accumulation of Methylglyoxal is associated with the low constitutive expression of glyoxalase-2 in adipose tissue. [glyoxalase II] (Rattus norvegicus) PubMed

 26651.

miR-146a could down-regulate the SOD2 protein expression.[miR-146a] (Rattus norvegicus) PubMed

 26652.

Monitoring the attachment and detachment of neurexin (Nrx)-coated quantum dots measures the rates of Nrx/neuroligin interaction in the hippocampus. (Rattus norvegicus) PubMed

 26653.

Data indicate that c-Myb is a functional target gene that is involved in miR-150-mediated H2O2-induced cardiac cell apoptosis: [c-myb] (Rattus norvegicus) PubMed

 26654.

(Erbin) Erbin mediates catecholamine-induced beta2-adrenergic receptor/Her2 complexation in cardiomyocytes, conferring protection from apoptosis. (Rattus norvegicus) PubMed

 26655.

The expression of miR-30b-5p is down-regulated in cardiac hypertrophy, and restoration of its function inhibits the expression of CaMKIIdelta.[MicroRNA-30b-5p] (Rattus norvegicus) PubMed

 26656.

NDP kinase and histidine kinase functions of nm23-H1 are necessary for glucose-induced membrane association of Rac1 and ensuing insulin secretion. (Nm23-H1 Nucleoside Diphosphate Kinase) (Rattus norvegicus) PubMed

 26657.

oxidative stress induces Tnfaip8 l1/Oxi-beta, which results in increased autophagy by its exclusive binding with FBXW5 to stabilize TSC2 (Rattus norvegicus) PubMed

 26658.

These findings demonstrate that regulated protein motions underlie kinase activation.[ERK2] (Rattus norvegicus) PubMed

 26659.

(motilin receptor) In a model of postoperative pain, motilin receptor expression is detected in hippocampus. (Rattus norvegicus) PubMed

 26660.

Thrombin activated a PLC/Ca(2+)/CaMKII/PKCalpha/p42/p44 MAPK and JNK1/2 pathway, which in turn triggered AP-1 activation and ultimately induced MMP-9 expression.[PI-PLC] (Rattus norvegicus) PubMed

 26661.

Aging-induced proteostatic changes in the rat hippocampus identify ARP3, NEB2 and BRAG2 as a molecular circuitry for cognitive impairment. (Rattus norvegicus) PubMed

 26662.

Data (including data from transgenic rats) suggest that, with aging, hypothalamus decline in number, activity, and fibrils/cell projections of GnIH neurons (especially in dorsomedial hypothalamic nucleus). [GnIH, gonadotropin-inhibitory hormone] (Rattus norvegicus) PubMed

 26663.

Data suggest down-regulation of dynorphin/kappa-opioid receptor signaling and up-regulation of neurokinin B/Nk3r signaling trigger onset of puberty (onset of pulsatile luteinizing hormone secretion) in young female rats. [Nk3r, neurokinin 3 receptor] (Rattus norvegicus) PubMed

 26664.

Gain- and loss-of-function studies of selected microRNAs (miR-146a and miR-183 cluster) were conducted to identify target pain mediators regulated by these selective microRNAs in glial cells.[miR146a] (Rattus norvegicus) PubMed

 26665.

A set of miRNAs is differently expressed in the aorta of high salt treated rats with miR-320 increased and miR-26b and -21 decreased, through beta1 and beta3-adrenoreceptor pathways.[miR26b] (Rattus norvegicus) PubMed

 26666.

An intestinal trefoil factor-specific receptor appears to be present on the three types of intestinal epithelial cells.[ITFR] (Rattus norvegicus) PubMed

 26667.

The study showed that serum antihyperlipidemic and antiatherogenic activity of statin may involve the induction of lecithin:cholesterol acyl transferase . (Rattus norvegicus) PubMed

 26668.

CORM-2 partially recovered mitochondrial respiration and ultrastructure alteration, and lowered caspase-3 expression and the release of cytochrome c (Rattus norvegicus) PubMed

 26669.

It was concluded that thyroid hormone inhibits IGF-I-stimulated glucose uptake and cell proliferation in L6 myoblasts via integrin alphavbeta3-mediated modulatory actions.[integrin alphavbeta3] (Rattus norvegicus) PubMed

 26670.

Central visfatin improved glucose homeostasis by increasing insulin secretion and insulin sensitivity at euglycemia through the hypothalamus in diabetic rats.[Insulin] (Rattus norvegicus) PubMed

 26671.

Report dynamic changes in the hippo signaling pathway during liver regeneration, which stabilize when the liver-to-body weight ratio reaches homeostatic levels. (Rattus norvegicus) PubMed

 26672.

Peroxisomal multifunctional enzyme type 1 (rpMFE-1) undergoes Posttranslational Modification on several N epsilon-Lys residues under PPAR-alpha-mediated peroxisome proliferation. (Rattus norvegicus) PubMed

 26673.

Marked reductions in both RNA and protein levels of Emi1 (early mitotic inhibitor 1) were also detected in Tbeta4 -downregulated IEC-6 cells.[Thymosin beta4] (Rattus norvegicus) PubMed

 26674.

Structural changes in CaM that arise directly from site directed mutagenesis of calcium binding domains alter activation gating of Cav1.2 channels.[Cavbeta2a] (Rattus norvegicus) PubMed

 26675.

Identify miR-182 as an important regulator of FoxO3 expression that participates in the control of muscular atrophy-inducing genes during catabolic diseases. (Rattus norvegicus) PubMed

 26676.

The CaMKIIbeta-mediated activation of LIMK1 plays a crucial role in BDNF-induced enhancement of primary neurite formation.(CaMKIIbeta) (Rattus norvegicus) PubMed

 26677.

Suggest that miR-21 promotes the development of heart failure with preserved left ventricular ejection fraction by up-regulating the expression of anti-apoptotic gene Bcl-2 and thereby promoting cardiac fibrosis. (Rattus norvegicus) PubMed

 26678.

The levels of serum miR-21 and miR-181a may be valuable for evaluating the development of chronic obstructive pulmonary disease in heavy smokers.[Mir 181a] (Rattus norvegicus) PubMed

 26679.

Calpain contributes to sarcolemmal disruption immediately after reperfusion following 30-min coronary occlusion, but has little effects during ischaemia and after reperfusion in 90-min coronary occlusion.[Calpain] (Rattus norvegicus) PubMed

 26680.

These data support a strong correlation of H2A.1 expression with undifferentiated cells and overall epigenetic reprogramming in dedifferentiation and maturation of undifferentiated cells, rather than with normal cellular proliferation.[H2A.1] (Rattus norvegicus) PubMed

 26681.

miR-9 regulation is mediated, at least in part, by Mef2C binding but that expressed miR-9 has the capacity to reduce inhibitory HDAC4, stabilizing its own expression in a positive feedback mechanism. (Rattus norvegicus) PubMed

 26682.

(prorenin receptor) Prorenin receptor is augmented in medullary collecting ducts in response to low-salt diet. (Rattus norvegicus) PubMed

 26683.

prt6 may be involved in the pathophysiology of the onset of drug-induced schizophrenia-like symptoms.[Prt6] (Rattus norvegicus) PubMed

 26684.

Loss of alpha(E)-catenin expression leads to decreased bone morphogenetic protein-7 expression and decreased ability of the aging kidney to repair following injury.[alpha(E)-catenin] (Rattus norvegicus) PubMed

 26685.

These findings indicate that miR-29b represses translation of Men1 mRNA, in turn affecting intestinal epithelial homoeostasis by altering IEC apoptosis. (Rattus norvegicus) PubMed

 26686.

Subsequent experiments also proved that both the rno-miR-466d and the human hsa-miR-466, which are orthologs of the miR-467 gene family, could effectively down-regulate the levels of rat and human CAR protein expression, respectively[mir466] (Rattus norvegicus) PubMed

 26687.

K2P3.1 and K2P9.1 undergo rapid dynamin-dependent endocytosis [K2P3.1][K2P9.1] (Rattus norvegicus) PubMed

 26688.

our results revealed that delayed kisspeptin-10 treatment reduces neuronal cell death by activation of SOD activity. (Rattus norvegicus) PubMed

 26689.

IGFBPrP1 has a role in inducing liver fibrosis by inducing hepatic stellate cell activation and hepatocyte apoptosis via Smad2/3 signaling [IGFBPrP1] (Rattus norvegicus) PubMed

 26690.

BMP-9 potently suppressed follicle-stimulating hormone-induced progesterone production, whereas it did not affect follicle-stimulating hormone-induced estradiol production by granulosa cells. [BMP-9] (Rattus norvegicus) PubMed

 26691.

This study examined whether pregnancy induces resistance to the anorectic effect of fatty acid synthase inhibition; malonyl-coenzyme A (CoA) in the hypothalamus; and changes in hypothalamic AMPK signaling associated with thermogenesis.[malonylCOA; AMPK] (Rattus norvegicus) PubMed

 26692.

alternative splicing of CaMKIIbeta variants in developing neurons may serve as a developmental switch for actin cytoskeleton-associated isoforms[CaMKIIbeta] (Rattus norvegicus) PubMed

 26693.

Ulinastatin is able to inhibit neuroinflammation by interfering with NF-kB signaling. [Ulinastatin] (Rattus norvegicus) PubMed

 26694.

MALAT1 upregulation represents a critical pathogenic mechanism for diabetes-induced microvascular dysfunction.[MALAT1] (Rattus norvegicus) PubMed

 26695.

Identify the miR-15 family as a novel regulator of cardiac hypertrophy and fibrosis acting by inhibition of the TGFbeta-pathway. (Rattus norvegicus) PubMed

 26696.

a wide distribution of phoenixin in the hypothalamus. [phoenixin] (Rattus norvegicus) PubMed

 26697.

ROCK1 mediates the effects of miR-135a in tendon stem/progenitor cell.[miR-135a] (Rattus norvegicus) PubMed

 26698.

we identified a novel miRNA, (PC-3p-3469_406), referred to as rno-miR-676-1, which was upregulated in rats with cerebral ischemia after fastigial nucleus stimulation[miR-676-1] (Rattus norvegicus) PubMed

 26699.

ZO-3 depletion did not affect cell cycle progression but increased cell detachment. (zona occludens 3) (Rattus norvegicus) PubMed

 26700.

Insulin receptor substrate-1 (IRS-1) is recruited to interact with the IR-catalyzed phospho-tyrosine cav-2, which facilitates IRS-1 association with and activation by IR to initiate IRS-1-mediated downstream signaling.[IRTK] (Rattus norvegicus) PubMed

 26701.

progranulin may be a novel therapeutic target that provides vascular protection, anti-neuroinflammation, and neuroprotection (Rattus norvegicus) PubMed

 26702.

Results suggest that peripheral activation of P2Y1, P2Y6 and P2Y11 receptors plays a pronociceptive role in formalin-induced pain. (P2ry11) (Rattus norvegicus) PubMed

 26703.

Chronic stress has long-term effects on pregnancy success, even post-stressor, that are mediated by RFRP3.[RFRP3] (Rattus norvegicus) PubMed

 26704.

It was shown that angiotensin II (ANGII)-angiotensin II type 1 receptors (AT1R) siganlling in type II cells activates an inwared current.(ANG II; AT1R) (Rattus norvegicus) PubMed

 26705.

nuclear translocation of CaMKIIdelta3 following dephosphorylation at Ser(332) by PP1 likely accounts for BDNF expression and subsequent neurite extension and survival of dopaminergic neurons.[CamKIIdelta3] (Rattus norvegicus) PubMed

 26706.

these results highlight the importance of the signaling pathway involving epistasis between Themis1 and Vav1 in the control of Treg suppressive function and susceptibility to IBD development. (Rattus norvegicus) PubMed

 26707.

These results indicated a role for the miR29b-Dnmt3a/3b-DNA methylation axis in mouse early embryonic development, and we provide evidence that miR29b is indispensable for mouse early embryonic development (Rattus norvegicus) PubMed

 26708.

The results obtained indicate the possible use of a dual PPARbeta/delta antagonist/PPARgamma agonist to counteract primary and secondary signs of Parkinson's disease neurodegeneration. [PPAR beta] (Rattus norvegicus) PubMed

 26709.

the Par-3-aPKC complex plays a crucial role in the maintenance of hepatocyte polarity and sealing of the bile canalicular lumen.[aPKC] (Rattus norvegicus) PubMed

 26710.

propose that isoprenylated Di-Ras2 forms a tight complex with SmgGDS in cytosol immediately after its synthesis, which lowers its affinity for guanine nucleotides [smgGDS protein] (Rattus norvegicus) PubMed

 26711.

recombinant tissue plasminogen activator contributes to the control of brain BDNF synthesis through a plasmin-independent potentiation of NMDA receptors signaling.[Plasmin] (Rattus norvegicus) PubMed

 26712.

(pro)renin receptor activation could trigger hypoxia/reoxygenation-induced apoptosis in H9c2 cells, partially through the p38 MAPK/caspase 3 signaling pathway.[Prorenin receptor] (Rattus norvegicus) PubMed

 26713.

Rattin is present and functional in GH3 cells, but it lacks regulation by estrogens, suggesting that humanin could participate in the pathogenesis of pituitary tumors.[Rattin] (Rattus norvegicus) PubMed

 26714.

membrane-active substances other than bile acids also affect the activity of BASIC.[BASIC] (Rattus norvegicus) PubMed

 26715.

miR-29b prevents liver fibrogenesis by inhibiting HSC activation and inducing HSC apoptosis through inhibiting PI3K/AKT pathway [MIRN29b] (Rattus norvegicus) PubMed

 26716.

CD147 promoted the activation of HSCs and was a key molecule during hepatocellular carcinoma cell-hepatic stellate cells cross-talk in the rat liver. (Rattus norvegicus) PubMed

 26717.

These findings indicate that biased signaling of the beta-arrestin pathway through the AT1 receptor inhibits NHE3 activity in the proximal tubule at least in part due to changes in NHE3 subcellular localization. (Rattus norvegicus) PubMed

 26718.

VEGF/VEGFR/K-ras signaling pathway might promote the occurrence and development of hepatocellular carcinoma cells through regulating expression of miRNA21, which has potential clinical value for the development of therapies for hepatocellular carcinoma (Rattus norvegicus) PubMed

 26719.

Expression of miR-125b is time-dependent and miR-125b plays a regulatory role of angiogenesis during wound healing after burns. (Rattus norvegicus) PubMed

 26720.

the decrease of cyclic AMP level and increase of cytosolic free Ca(2+) as well as hydrogen peroxide levels associate with the reduced MPF level and meiotic resumption from diplotene arrest.[MPF] (Rattus norvegicus) PubMed

 26721.

These results demonstrated that miR-133a improves the cardiac function and fibrosis through inhibiting Akt in heart failure rats.[Microrna 133a] (Rattus norvegicus) PubMed

 26722.

Based on these quantitative data, we would propose that these bi-stable ChRs would be most suitable for enhancing the intrinsic activity of excitatory pyramidal neurons at a minimal magnitude of irradiance. (Rattus norvegicus) PubMed

 26723.

Results suggest that IGFBPrP1 initiates liver fibrosis by inducing inflammation, hepatic stellate cell activation and extracellular matrix deposition through the ERK1/2 pathway.[Insulin-like growth factor binding protein-related protein 1] (Rattus norvegicus) PubMed

 26724.

miR-21 directly targeted the 3'-untranslated region of Fas ligand (FASLG) and inhibited the expression of FASLG, which suggests that miR-21 promoted BRL-3A cell proliferation by reducing FASLG expression. [MIRN-21] (Rattus norvegicus) PubMed

 26725.

The decrease of lncRNA-NR024118 induced by Ang II is mediated by AT1 receptors not AT2 receptors, since it is reversed by losartan. lncRNA-NR024118 (Rattus norvegicus) PubMed

 26726.

Notogeinsenoside R1 reduces blood pressure of spontaneously hypertensive rats through induction of iNOS regulated by long non-coding RNA AK094457. (Rattus norvegicus) PubMed

 26727.

Closure of potassium channels favors opening of the Tl(+)-induced mitochondrial permeability transition pore (MPTP) in Ca(2+)-loaded rat liver mitochondria. [MPTP] (Rattus norvegicus) PubMed

 26728.

Nutrient-deprivation autophagy factor-1 antagonizes the degree of autophagy in cardiomyocytes and enhances cell survival during starvation conditions. [nutrient-deprivation autophagy factor-1] (Rattus norvegicus) PubMed

 26729.

Rat Humanin is encoded and translated in mitochondria and is localized to the mitochondrial compartment where it regulates ROS production. (Rattus norvegicus) PubMed

 26730.

CHP3 functions as a novel negative regulator of cardiomyocyte hypertrophy via inhibition of GSK3alpha/beta phosphorylation.[CHP3] (Rattus norvegicus) PubMed

 26731.

UBR3/6 regulate cardiomyocyte Nav 1.5 channel protein levels via the ubiquitin-proteasome pathway.[UBR6] (Rattus norvegicus) PubMed

 26732.

Smad3 was a direct and functional target of miR-23b in heat-denatured fibroblasts.[miR23] (Rattus norvegicus) PubMed

 26733.

continuous WldS activity in the axonal compartment is both necessary and sufficient to delay axonal degeneration [WldS] (Rattus norvegicus) PubMed

 26734.

MRTF-A enhanced the migration of bone marrow stem cell, and overexpression of MRTF-A in bone marrow stem cell prevented hydrogen peroxide-induced apoptosis in primary cardiomyocytes ex vivo. (Rattus norvegicus) PubMed

 26735.

This report shows that Cx43 participates in the regulation of vascular permeability in sepsis and that the mechanism is related to the Rock1-MLC20 phosphorylation pathway.[MLC20] (Rattus norvegicus) PubMed

 26736.

ZNF573 delivery to hypothalamus delays puberty by impairing the transition of a transcriptional network from an immature repressive epigenetic configuration to one of activation. (Rattus norvegicus) PubMed

 26737.

Data suggest that a dietary component, the medium-chain fatty acid decanoate, can down-regulate expression of Hsd3b2 in adrenals/ovaries in model of polycystic ovary syndrome. [Hsd3b2, 3 beta-hydroxysteroid dehydrogenase type 2] (Rattus norvegicus) PubMed

 26738.

Anti-hypertensive effect of Lycium barbarum L. involves down-regulation of renal endothelial cell lncRNA sONE. (Rattus norvegicus) PubMed

 26739.

Ursolic acid can affect the uptake of rosuvastatin in hepatocytes by inhibiting the transport of OATP1B1, and gene mutation of OATP1B1 may cause different effects on its transport of rosuvastatin. (Rattus norvegicus) PubMed

 26740.

This study partially uncovers the mechanism by which miR-10b or HOTAIR promotes malignant transformation of liver normal stem cells through down-regulating E-cadherin and inducing Epithelial- to-Mesenchymal Transition.[HOTAIR, miR 10b] (Rattus norvegicus) PubMed

 26741.

Data indicate that miR-sc8 affects phenotype modulation of Schwann cells by targeting Egfr, providing further insights into the regulatory role of miRNAs in peripheral nerve regeneration. [miR-sc8] (Rattus norvegicus) PubMed

 26742.

These findings indicate that memory reconsolidation for a cocaine-paired stimulus depends critically on DNMT activity in the basolateral amygdala.[DNMT] (Rattus norvegicus) PubMed

 26743.

Kir2 channels composed of Kir2.1-2.3 subunits are expressed in neuronal and glial cells in the DRG and spinal cord, contributing to sensory transduction and motor control. [Kir2.3] (Rattus norvegicus) PubMed

 26744.

These results suggest that kisspeptin and gonadotropin releasing hormone (GnRH) play major roles in modulating the activity of estrogen circuits at the onset of puberty.(GnRH) (Rattus norvegicus) PubMed

 26745.

Decreased miR-26b expression in visceral adipose tissue (VAT) may be involved in obesity-related insulin resistance by interrupting the PTEN/PI3K/AKT pathway. (Rattus norvegicus) PubMed

 26746.

miR-135 positively regulated the osteogenesis and bone regeneration of adipose-derived stem cells.[miR 135] (Rattus norvegicus) PubMed

 26747.

Vascular peroxidase 1/VPO1 promotes ox-LDL-induced vascular smooth muscle cell calcification. (Rattus norvegicus) PubMed

 26748.

Exercise managed to prevent most of the disturbances in insulin signaling caused by fructose diet (except phosphorylation of IRS1 at Tyr 632 and phosphorylation and protein expression of ERK1/2) and consequently restored function of eNOS.[Insulin] (Rattus norvegicus) PubMed

 26749.

Portal hypertension may induce the proliferation, migration and activation of hepatic stem cells by up-regulating miR-9a-5p expression, which then targets Sirt1. (Rattus norvegicus) PubMed

 26750.

NONRATT021972 siRNA treatment can decrease the expression levels of P2X7 mRNA and protein.[NONRATT021972] (Rattus norvegicus) PubMed

 26751.

MICA expression in recipients' heart and anti-MICA antibodies in recipients' sera may associated with high risk of acute rejection in rat-to-mouse transplantation. (Rattus norvegicus) PubMed

 26752.

MAPK1 was able to increase the proliferation of cardiomyocytes via up-regulating the expression of MALAT1 through PI3K/AKT signaling pathway. (Rattus norvegicus) PubMed

 26753.

miR-449 regulates the SIRT1/p53/BAX pathway, which may be its possible mechanism in modulating cell apoptosis of cisplatin-induced Acute kidney injury. (Rattus norvegicus) PubMed

 26754.

hepatic microRNA rno-miR-125b-3p is suppressed by quercetin-induced hepatic gamma-glutamyl hydrolase expression in rats [miR-125-3p] (Rattus norvegicus) PubMed

 26755.

Non-muscle myosin regulatory light chain (nmMLC20) could promote the senescence and dysfunctions of endothelial progenitor cells in pulmonary artery hypertension through up-regulation of NOX in a phosphorylation-dependent manner [mlc20 or MYL20] (Rattus norvegicus) PubMed

 26756.

Mir181 microrna was up-regulated in the course of seizure-induced neuronal apoptosis. Antagomir targeting miR-181a leads to a neuroprotective response. (Rattus norvegicus) PubMed

 26757.

The expression of miR-19b was significantly up-regulated in acute necrotizing pancreatitis. (Rattus norvegicus) PubMed

 26758.

This study indicates that a downregulation of Cdh1 expression in spinal dorsal horn is involved in molecular mechanisms underlying the maintenance of neuropathic pain. [APC/C-Cdh1] (Rattus norvegicus) PubMed

 26759.

miR-20, Rest and Wnt signaling are suggested to be involved in a regulatory circuit that can modulate the neural differention of neural progenitor cells. [mir-20] (Rattus norvegicus) PubMed

 26760.

These findings highlight an association between the altered lipid droplets protein localization of dysferlin and ATGL and myocardial dysfunction.[ATGL] (Rattus norvegicus) PubMed

 26761.

These findings reveal an inherent regulatory role of ZAKbeta to antagonize ZAKalpha and to subsequently downregulate the cardiac hypertrophy and apoptosis induced by ZAKalpha.[ZAK alpha, ZAK beta] (Rattus norvegicus) PubMed

 26762.

Vasorelaxant adenine can suppress Ca(2+) contraction signaling pathways via aortic adenine receptor/PKA activation in vascular smooth muscle cells. (Rattus norvegicus) PubMed

 26763.

These results suggested that Astragalus polysacchrides could improve muscle wasting through Akt/mTOR, ubiquitin proteasome and autophagy signalling, and SLC38A2 may be one of potential targets. (Rattus norvegicus) PubMed

 26764.

miR-133b-5p might play a particularly important role in the cardioprotective effect of morphine preconditioning by regulating the target gene Fas [mirn133b, rat] (Rattus norvegicus) PubMed

 26765.

Overexpression or knockdown of miR-434-3p in vivo demonstrated it was a negative post-transcriptional regulator of eIF5A1 expression and influenced AChRs expression. (Rattus norvegicus) PubMed

 26766.

Data suggest that expression of microRNA-9 (Mir9) in cardiac fibroblasts is involved in regulation of expression of Pdgfr-beta (platelet-derived growth factor beta receptor) and in prevention of cardiac fibrosis; here, overexpression of Mir9 inhibits cardiac fibrosis in primary cardiac fibroblasts by targeting Pdgfr-beta. [Mir9, microRNA-9] (Rattus norvegicus) PubMed

 26767.

these results suggested that miRNA-29a suppresses cardiac fibrosis and fibroblasts proliferation via targeting VEGF-A/MAPK signal pathway implicating that miRNA-29a might play a role in the treatment of cardiac fibrosis. (Rattus norvegicus) PubMed

 26768.

rHSG overexpression induces the apoptosis of rat glioma cells.[rHSG] (Rattus norvegicus) PubMed

 26769.

An increased and decreased expression of miR-sc3 promoted and reduced the proliferation and migration of primary Schwann Cell, respectively. [miR-sc3] (Rattus norvegicus) PubMed

 26770.

down-regulation of miRNA-1 can prevent the decrease and redistribution of Cx43, which will protect the heart from ischemia-reperfusion injury [review] (Rattus norvegicus) PubMed

 26771.

These findings suggest that water deprivation may elevate the renal full-length (P)RR levels via reducing the expression of furin.[Prorenin receptor] (Rattus norvegicus) PubMed

 26772.

Compared with the rats in the control group, the serum activity of xanthine oxidase was significantly higher and that of PON1 was significantly lower in the rats in the model nonalcoholic fatty liver disease group (P<0.01). [xanthine oxidase] (Rattus norvegicus) PubMed

 26773.

lncRNAs are differentially expressed in the LAPV and LAA in patients with AF. AK055347 may contribute to the pathogenesis of AF by dysregulating mitochondrial energy production via regulation of Cyp450, ATP synthase and MSS51. (Rattus norvegicus) PubMed

 26774.

PEDF can protect against hypoxia-induced activation of the NLRP3 inflammasome by inhibiting mitochondrial fission though PEDFR/iPLA2.[PEDFR] (Rattus norvegicus) PubMed

 26775.

miR128 inhibition attenuated I/R injuryinduced cardiomyocyte apoptosis by the targeted activation of PPARG signaling. (Rattus norvegicus) PubMed

 26776.

critical role for MARK2 in overcoming Nogo-66-induced inhibition of axon outgrowth in neurons[nogo 66] (Rattus norvegicus) PubMed

 26777.

trimetazidine exerts protective effects against cardiac I/R injury through cardiac miRNA21 expression, Akt, and the Bcl2/Bax pathway. Therefore, the present study provided evidence regarding the protective effects of miRNA21 on cardiac I/R injury following treatment with trimetazidine in vivo (Rattus norvegicus) PubMed

 26778.

Suggest role for glutamate carboxypeptidase II in neuronal apoptosis in rats with ischemic brain injury. (Rattus norvegicus) PubMed

 26779.

Study establishes KIAA0319 as a novel player in axon growth and regeneration with the ability to repress the intrinsic growth potential of axons; describes a novel regulatory mechanism operating during peripheral nervous system and central nervous system axon growth, and offers novel targets for the development of effective therapies to promote axon regeneration [KIAA0319] (Rattus norvegicus) PubMed

 26780.

MALAT1 downregulated the expression of ELAVL1 and inhibited pyroptosis in diabetic nephropathy. (Rattus norvegicus) PubMed

 26781.

These results indicated that miR-199b attenuated acute spinal cord injury at least partly through IKKbeta-NF-kappaB signaling pathway and affecting the function of microglia.[miR-199b] (Rattus norvegicus) PubMed

 26782.

miR-27a may protect against brain injury via suppressing FoxO3a-mediated neuronal autophagy following traumatic brain injury [miR-27a] (Rattus norvegicus) PubMed

 26783.

Usp2-69 overexpression alleviates the progression of rat anti-Thy1.1 nephritis.[Usp2-69] (Rattus norvegicus) PubMed

 26784.

miR-590-3p was strikingly reduced in experimental autoimmune myocarditis; miR-590-3p is a novel NF-KB-related miRNA that directly targets the p50 subunit (Rattus norvegicus) PubMed

 26785.

characteristic differences between Kv11.1a/1b and Kv11.3 determined at room temperature do not necessarily apply to physiological conditions [Kv11.1a/1b][Kv11.3] (Rattus norvegicus) PubMed

 26786.

we successfully identified two novel dysregulated miRNAs (196b-5p and 352) and confirmed miR-128a-3p downregulation in SE-induced epileptogenesis. Further functional assays are required to understand the role of these miRNAs in MTLE pathogenesis. (Rattus norvegicus) PubMed

 26787.

chondroitinase C effectively degrades and inactivates inhibitory chondroitin sulfate proteoglycans present in the endoneurial Schwann cell basal lamina and does so more specifically than chondroitinase ABC [chondroitinase C] (Rattus norvegicus) PubMed

 26788.

MIR192: miR-192-5p mediates hypoxia/reoxygenation-induced apoptosis in cardiomyocytes by targeting FABP3 and represents a potential target for prevention of myocardial ischemia/reperfusion injury. (Rattus norvegicus) PubMed

 26789.

The miR-34a/SIRT1/p53 signaling pathway is activated in hepatocytes but not hepatic stellate cells during liver fibrosis (Rattus norvegicus) PubMed

 26790.

The Betaine Aldehyde Dehydrogenase enzyme is involved in the physiological cardiac hypertrophy adaptation response. Betaine Aldehyde Dehydrogenase increase its expression and activity in physiological cardiac hypertrophy. [Betaine Aldehyde Dehydrogenase] (Rattus norvegicus) PubMed

 26791.

MiRNA-29a and AGT mRNA expressions were negatively correlated in a rat model of diabetic retinopathy (DR). Overexpression of miRNA-29a could down-regulate AGT expression, thereby preventing the development of DR. [miRNA-29a, rat] (Rattus norvegicus) PubMed

 26792.

The association of mitochondrial microphthalmia-associated transcription factor (MITF) with pyruvate dehydrogenase (PDH) emerges as an important regulator of mast cell function. Our findings indicate that PDH could arise as a new target for the manipulation of allergic diseases [microphthalmia-associated transcription factor] (Rattus norvegicus) PubMed

 26793.

a novel metabolic peptide that reduces food intake and modulates whole body energy balance (Rattus norvegicus) PubMed

 26794.

the high resolution positional mapping study located the rat QT-interval locus to a <42.5kb region on RNO10. This region contained no variants in protein-coding sequences, but a prominent contiguous 19bp indel polymorphism was noted within a novel predicted long non-coding RNA (lncRNA), which we named as Rffl-lnc1. (Rattus norvegicus) PubMed

 26795.

MCU and EMRE proteins were mainly targeting to the IMM-outer mitochondrial membrane. (Rattus norvegicus) PubMed

 26796.

lncRNA uc.48+ siRNA improved diabetic sympathetic neuropathy in type 2 diabetic rats through regulating the expression of P2X7[LncRNA uc.4] (Rattus norvegicus) PubMed

 26797.

Data suggest that Cefip (cardiac-enriched Fhl2-interacting protein) interacts with Fhl2 (four and a half LIM domains protein-2) and modulates calcineurin signaling in cardiomyocytes; Cefip is located at sarcomeric z-disc and is up-regulated in several models of cardiomegaly. [Cefip, cardiac-enriched Fhl2-interacting protein] (Rattus norvegicus) PubMed

 26798.

C9orf116 may promote cell proliferation.[C9orf116] (Rattus norvegicus) PubMed

 26799.

Data suggest that phosphorylation of PSD95 (postsynaptic density protein 95) at Ser561 in guanylate kinase domain is mediated by Par1/Pard1 (partitioning-defective 1 kinase), regulates a conformational switch, and is important for bidirectional neuronal plasticity (as found in cultured hippocampal neurons from embryonic rats). [Pard1, partitioning-defective 1 kinase] (Rattus norvegicus) PubMed

 26800.

Chloride conducting light activated channel GtACR2 can produce both cessation of firing and generation of action potentials in cortical neurons in response to light. [GtACR2] (Rattus norvegicus) PubMed

 26801.

Nogo-B was found at the endoplasmic reticulum and focal contacts and co-localized with F-actin and alpha-Tubulin on resting and migrating VSMCs. Downregulation reduced RhoA, HDAC activity, 3D collagen matrix migration, and F-actin filaments, but increased alpha-tubulin acetylation, cell area, 2D chemotaxis, and multinucleate cell generation. Nogo-B modulates MTs and actin organization/dynamics via Rho A and HDAC-6. Rtn4B. (Rattus norvegicus) PubMed

 26802.

Brefeldin A activated p38 MAPK in hepatic stellate cells in an IRE1alpha-dependent way. Pretreatment with IRE1alpha inhibitors also prevented increased p-Smad3 accumulation in the nucleus. An IRE1alpha-p38 MAPK-Smad pathway may be responsible for the fibrogenic action of BFA on HSC. IRE1A. (Rattus norvegicus) PubMed

 26803.

This study provides evidence that reduced circular ANRIL long non-coding RNA expression could prevent coronary atherosclerosis by reducing vascular endothelial cells apoptosis and inflammatory factor expression. [ANRIL long non-coding RNA] (Rattus norvegicus) PubMed

 26804.

activation of the A1 adenosine receptor by N(6)-cyclohexyladenosine could prevent intracerebral hemorrhage-induced secondary brain injury via the P38-MAPKAP2-Hsp27 pathway.[Mapkap2] (Rattus norvegicus) PubMed

 26805.

NONRATT021972 siRNA treatment effectively suppressed the increase in [Ca(2+)]i induced by OGD or P2X7 agonists (ATP or BzATP) in PC12 cells[NONRATT021972] (Rattus norvegicus) PubMed

 26806.

serum norepinephrine (NE) and epinephrine (EPI) concentrations were decreased in the MI rats that were treated with NONRATT021972 siRNA[NONRATT021972] (Rattus norvegicus) PubMed

 26807.

Inhibition of p38 MAPK signaling decreased nc021972-induced expression of the P2X7 receptor and [Ca(2+)]i increment upon P2X7 receptor activation[nc021972] (Rattus norvegicus) PubMed

 26808.

the increased IRS1 expression may mediate the insulin-sensitizing effects of sodium butyrate.[Insulin] (Rattus norvegicus) PubMed

 26809.

Both phosphoramidon (inhibitor of the known dynorphin converting enzyme neprilysin) and opiorphin (inhibitor of neprilysin and aminopeptidase N) blocked cortical bioconversion to dynorphin B(1-7), wheras only opiorphin blocked striatal bioconversion to dynorphin B(2-13). (Rattus norvegicus) PubMed

 26810.

Optogenetic stimulation of channelrhopdopsin-2 (ChR)-expressing spinal astrocytes induced pain hypersensitivity in a reversible and time-dependent manner, which was accompanied by glial activation, NR1 phosphorylation, ATP release, and the production of proalgesic mediators (Rattus norvegicus) PubMed

 26811.

purinergic P2Y11 receptors stimulation improves vascular function and mitigates oxidative stress in the setting of acute systemic inflammation, revealing salutary effects and therapeutic potential in pathologies associated with endothelial dysfunction. (Rattus norvegicus) PubMed

 26812.

MCP-1/sSiglec-9 regenerates peripheral nerves by inducing tissue-repairing M2 macrophages.[Siglec9] (Rattus norvegicus) PubMed

 26813.

cardioprotective function of HOTAIR is partly based on the negative regulation of miR-1. (Rattus norvegicus) PubMed

 26814.

Suggest that knockdown of ANRIL expression aggravates H2O2-induced injury in PC-12 cells by targeting miR-125a. (Rattus norvegicus) PubMed

 26815.

the PERK pathway mediated single prolonged stress-induced neural apoptosis in the medial prefrontal cortex.[PERK] (Rattus norvegicus) PubMed

 26816.

PPAR-beta increases PGC-1alpha content via a reduction in protein degradation. [PPAR-beta] (Rattus norvegicus) PubMed

 26817.

these results suggest that high glucose induces myocardial energy metabolism disorder via decrease of CaSR expression, and activation of gp78-ubiquitin proteasome system.[gp78] (Rattus norvegicus) PubMed

 26818.

miR-219-5p plays a crucial role in alleviating morphine tolerance by inhibiting the CaMKII/NMDA receptor pathway. Overexpression of miR-219-5p may be a potential strategy to ameliorate morphine tolerance. (Rattus norvegicus) PubMed

 26819.

The flow-mediated miR-10a expression is regulated by Kruppel-like factor 2 through modulation in RARalpha-RARE binding, with the consequent regulation in GATA6/VCAM-1 in endothelial cells. (Rattus norvegicus) PubMed

 26820.

endothelial specificity and activation of both NO and PG-signaling pathways in vasodilation of resistance arteries [placental protein 13] (Rattus norvegicus) PubMed

 26821.

DOR1 and DOR2 subtype selective ligands can act differentially on individual ventral tegmental area (VTA) neurons and that when both are expressed in a single neuron the postsynaptic response to one does not predict the presence or valence of the response to the other. DOR subtypes not only differentially control individual neurons, but also modulate different, partially overlapping, subpopulations of VTA neurons. [DOR2] (Rattus norvegicus) PubMed

 26822.

Although knockdown of IL-10R1 protein in nociceptors innervating the gastrocnemius muscle by intrathecal antisense oligodeoxynucleotide did not change nociceptive threshold in naive rats, it unveiled latent muscle hyperalgesia in rats submitted to eccentric exercise 12 days ago[interleukin 10 receptor 1] (Rattus norvegicus) PubMed

 26823.

the miR-106b~25 cluster is involved in timely cell cycle entry of hepatocytes after partial hepatectomy [miR106] (Rattus norvegicus) PubMed

 26824.

Increasing miR-101a-3p expression in the amygdala increases anxiety-like behavior in rats. microRNA miR-101a-3p targets Ezh2. (Rattus norvegicus) PubMed

 26825.

Transitional endoplasmic reticulum ATPase (TERA) is a potential SCIRR69-interacting protein in endoplasmic reticulum stress. TERA. (Rattus norvegicus) PubMed

 26826.

The upregulation of miR27 inhibits the pathogenesis of osteoarthritis by targeting leptin and inhibiting the NF-kappaB signaling pathway. [miR27] (Rattus norvegicus) PubMed

 26827.

The MGF E peptide showed an adverse effect on the expression level of vascular endothelial growth factor alpha in BMSCs under severe hypoxia but could make up for this deficiency through accelerating cell proliferation. (mechano-growth factor, rat) (Rattus norvegicus) PubMed

 26828.

miR-92a overexpression modulates MMP9 and TIMP3 expression levels and prevents H2O2-induced VSMC migration by repressing SIRT1, implying that miR-92a may exert an atheroprotective role in atherogenesis. (Rattus norvegicus) PubMed

 26829.

lncRNA BC168687 may participate in the pathogenesis of DNP mediated by P2X7 receptor, which will provide a novel way for the study of the pathogenesis of diabetes mellitus complicated with neuropathic pain and its prevention and treatment. (Rattus norvegicus) PubMed

 26830.

Overexpression of miR-146 may alleviate the irreversible injury associated with reperfusion and the effects may be achieved by inhibiting the NF-kappaB/TNF-alpha signaling pathway. [miR-146] (Rattus norvegicus) PubMed

 26831.

This study demonstrates an important role of 20-HETE in increasing BP and altering vascular responsiveness in L-NAME-induced hypertension model, which suggests a possible involvement of 20- HETE in essential hypertension development in humans. [20-Hydroxyeicosatetraenoic acid] (Rattus norvegicus) PubMed

 26832.

MicroRNA-449a was significantly upregulated in both neonatal rat ventricular myocytes and H9C2 cells subjected to Hypoxia/Reoxygenation. [MicroRNA-449a] (Rattus norvegicus) PubMed

 26833.

these results suggest that MALAT1 aggravates cardiac inflammation and dysfunction in sepsis, which is achieved via interaction with miR-125b and p38 MAPK/NFkappaB. [LncRNA MALAT1] (Rattus norvegicus) PubMed

 26834.

The current results demonstrated that lncRNA ENSRNOG00000037522 serves a pivotal role in the podocyte epithelialmesenchymal transition in Diabetic nephropathy. [lncRNA ENSRNOG00000037522] (Rattus norvegicus) PubMed

 26835.

these results indicate that silencing BC168687 expression may downregulate the increased expression of P2X7 receptors in SGCs induced by a HGHF environment. (Rattus norvegicus) PubMed

 26836.

MRF4 acts by stabilizing a repressor complex that controls MEF2 activity.[MEF2] (Rattus norvegicus) PubMed

 26837.

NFE2/miR432-5p is reduced and FAM3a is increased with exercise in a rat model of insulin sensitivity [miR-423-5p] (Rattus norvegicus) PubMed

 26838.

These observations provide evidence for IP-10 in a regulatory role in cold ischemia-elicited acute allograft rejection and in PRINS lncRNA expression[prins] (Rattus norvegicus) PubMed

 26839.

DJB (duodenal-jejunal bypass) improves renal function of obese diabetic rats. Data suggest that this improvement involves down-regulation of expression of Malat1 and its downstream target Saa3 in renal tissue. (Malat1 = metastasis associated lung adenocarcinoma transcript-1; Saa3 = serum amyloid A3 protein) [Malat1 = metastasis associated lung adenocarcinoma transcript-1] (Rattus norvegicus) PubMed

 26840.

Western blotting results revealed a novel mechanism underlying PEDFinduced H9c2 cell autophagy via the PEDFRmediated Atg5 pathway under hypoxic conditions. [PEDFR] (Rattus norvegicus) PubMed

 26841.

downregulated nuclear paraspeckle assembly transcript 1 decreased the expression of brain-derived neurotrophic factor through elevating miR-497[nuclear paraspeckle assembly transcript 1] (Rattus norvegicus) PubMed

 26842.

These results suggest that modification of Bone marrow-derived mesenchymal stem cells by dual expression of CXCR4 and IL-35 may provide an effective therapeutic strategy for inflammatory bowel disease.[IL-35] (Rattus norvegicus) PubMed

 26843.

giantin plays a pivotal role in coordinated production of aggrecan, link protein and type XI collagen in chondrocytes.[Link] (Rattus norvegicus) PubMed

 26844.

SIP may inhibit the inflammatory response by deactivating p65, thus reducing the myocardial damage caused by acute pancreatitis.[SIP] (Rattus norvegicus) PubMed

 26845.

canstatin might play a role in the stabilization of cardiac function through the modulation of L-type Ca(2+) channels activity in cardiomyocytes.[canstatin] (Rattus norvegicus) PubMed

 26846.

Local high expression of Apo-J in the peripheral regions may play a neuroprotective role by inhibiting apoptosis via the Omi/HtrA2 pathway after hemorrhage (Rattus norvegicus) PubMed

 26847.

HOTAIR was upregulated in sepsis-induced kidney injury, which promoted HK-2 cell apoptosis in kidney injury through the miR-22/HMGB1 pathway (HOTAIR). (Rattus norvegicus) PubMed

 26848.

First evidence on the peripheral activity of PNX and on its direct cardiomodulatory and cardioprotective role under both normal conditions and in the presence of metabolic disorders.[phoenixin-14 protein, rat]. (Rattus norvegicus) PubMed

 26849.

drd1a and drd2a dopamine receptors expression were higher only in males separated in the dark phase of the circadian cycle [drd2a] (Rattus norvegicus) PubMed

 26850.

Down-regulation of MALAT1 activates the PI3K/Akt signaling pathway to protect hippocampal neurons against autophagy and apoptosis in rats with epilepsy. (Rattus norvegicus) PubMed

 26851.

Pain thresholds of diabetic rats increased significantly compared with control. Expression of TRPV1 receptors in dorsal root ganglia (DRG) substantially decreased. Relative levels of TNF-alpha and IL-1beta in the serum of lncRNA BC168687 siRNA-treated rats were reduced. Phosphorylation (p)-ERK and p-p38 signaling pathways in DRG were also decreased [lncRNA BC168687]. (Rattus norvegicus) PubMed

 26852.

mast cells contribute to Mincle-mediated immunity through Syk activation triggered by association with the FcepsilonRIbetagamma complex.[FcerIb] (Rattus norvegicus) PubMed

 26853.

High miR181a expression is associated with glomerular mesangial cell hypertrophy. (Rattus norvegicus) PubMed

 26854.

Overexpression of TUSC7 inhibited the inflammation caused by microglia activation via miR-449a up-regulating PPAR-gamma. [long non-coding RNA TUSC7] (Rattus norvegicus) PubMed

 26855.

Our study provides insights into how Ubtor regulate cellular growth and mTOR signaling. Manipulations of Ubtor function may potentially be utilized to optimize mTOR signaling activities for treatments of cancers and other diseases. [UBTOR] (Rattus norvegicus) PubMed

 26856.

miR-92b-3p reverse the proliferaton of pulmonary artery smooth muscle cells under hypoxia condition. miR-92b-3p regulate the protein level of USP28. [miR-92b] (Rattus norvegicus) PubMed

 26857.

MAP7 recruits kinesin-1 dynamically to microtubules, leading to alterations in organelle transport behaviors, particularly pause/speed switching.[Kinesin 1] (Rattus norvegicus) PubMed

 26858.

Knockdown of miR-372 reduces nerve cell apoptosis in in spinal cord reperfusion injury via up-regulating Beclin-1 and enhancing autophagy. (Rattus norvegicus) PubMed

 26859.

CTMP increase with aging contributes to the aging-dependent decrease of brain ischemic tolerance.[CTMP] (Rattus norvegicus) PubMed

 26860.

After inhibiting the expression of MIRT1, the activation of NF-kappaB signaling pathway was inhibited, the damage of cardiac function and cardiomyopathy was alleviated, the area of myocardial fibrosis was decreased, the degree of myocardial apoptosis was decreased, the degree of oxidative stress and inflammatory injury was obviously improved. (MIRT1) (Rattus norvegicus) PubMed

 26861.

Matrix metallopeptidase 2 (MMP2) was identified as a target of miR-125 in H9c2 cardiomyocytes cells: [mir-125] (Rattus norvegicus) PubMed

 26862.

the role of CNPase, serine/threonine kinases, and MEL in the mPTP opening was examined.[mptp] (Rattus norvegicus) PubMed

 26863.

in vitro data collectively demonstrated that lncRNA CHRF silence protected H9c2 cells against lipopolysaccharide-induced injury via up-regulating miR-221[CHRF] (Rattus norvegicus) PubMed

 26864.

the purpose of the present study was to investigate the effect of high-intensity interval training (HIIT) and supplementation of flaxseed oil on plasma irisin, nesfatin-1 and resistin in male rats.[Irisin] (Rattus norvegicus) PubMed

 26865.

lncRNA-TCONS_00034812 modulates pulmonary artery smooth muscle cell proliferation and apoptosis, and participates in vascular remodeling during pulmonary arterial hypertension. (Rattus norvegicus) PubMed

 26866.

SRA1 promoted cardiac myofibroblast activation by acting as a competitive endogenous RNAs for miR-148b [miR-148b][SRA1 LncRNA] (Rattus norvegicus) PubMed

 26867.

we evidenced ENT2 as a target of insulin signaling and sensitive to dysregulation in diabetes, leading to chronically increased extracellular adenosine levels and thereby setting conditions conducive to kidney injury. (Rattus norvegicus) PubMed

 26868.

LncRNA UCA1 suppressed pilocarpine-induced epilepsy by inhibiting apoptosis of hippocampal neurons through miR-495/Nrf2-ARE pathway, and thereby inhibiting brain injury induced by seizure (Rattus norvegicus) PubMed

 26869.

MicroRNA-92a Mediates Endothelial Dysfunction in CKD. (Rattus norvegicus) PubMed

 26870.

a new role for nociceptin, acting as a neurotrophic peptide able to promote the survival and differentiation of developing cerebellar granule neurons, is reported.[Nociceptin] (Rattus norvegicus) PubMed

 26871.

MiR-7 inhibited the expression of EGFR and STAT3 to antagonize astrocyte activation, leading to the protection against brain injury after intracerebral hemorrhage in rats.[Mir7] (Rattus norvegicus) PubMed

 26872.

mhrt and myocardin form a regulation loop in the process of cardiac hypertrophy.[mhrt] (Rattus norvegicus) PubMed

 26873.

PSMA6 mRNA is post-transcriptionally regulated by miRNA-4490, whose expression is inversely correlated to PSMA6 protein expression. [MIR4490] (Rattus norvegicus) PubMed

 26874.

It may be concluded that PKD plays a central role in VR, and the mechanism may be related to its regulation of hypertrophy, fibrosis, inflammation and oxidative stress.[Protein Kinase D] (Rattus norvegicus) PubMed

 26875.

Free Ca(2+) in the physiological range greatly increases the sensitivity of the branched-chain alpha-ketoacid dehydrogenase kinase to inhibition by thiamine pyrophosphate.[branched-chain alpha-ketoacid dehydrogenase kinase] (Rattus norvegicus) PubMed

 26876.

Data suggest that a network of mitochondrial nitrite reductases (NR) is involved in NO2(-) mediated regulation of hemodynamics: [nitrite reductase (NR)] (Rattus norvegicus) PubMed

 26877.

NEAT1 knockdown or miR-124 overexpression inhibits amyloid-beta-induced apoptosis in PC-12 cells (NEAT1). (Rattus norvegicus) PubMed

 26878.

PLAP-1-positive inflammatory cells are involved in the pathogenesis of periodontitis[PLAP-1] (Rattus norvegicus) PubMed

 26879.

the anti-apoptotic effects of Let-7d-3p mimic during hypoxia challenge are due to direct targeting of HMGA2.[Let-7d] (Rattus norvegicus) PubMed

 26880.

the present results suggested that miR124 may improve functional recovery and supress neuronal cell apoptosis by blocking the mitochondrial apoptotic pathway in SCI rats. (Rattus norvegicus) PubMed

 26881.

LncRNA HOTAIR promotes renal interstitial fibrosis by regulating via the modulation of miR-124 expression and regulation of NOTCH1 signaling pathway. (Rattus norvegicus) PubMed

 26882.

miR590 promoted apoptosis in bone cells from rats with osteoarthritis by regulating the TGFbeta1/PI3K signaling pathway.[miR590] (Rattus norvegicus) PubMed

 26883.

V-ATPase c-subunit V0c is a key element in modulating neurotransmission and that its specific inactivation rapidly inhibited neurotransmission.[V0c] (Rattus norvegicus) PubMed

 26884.

The effect of miRNA-20 reducing the expression of MFN2 plays a role in promoting cardiomyocyte hypertrophy.[miRNA-20] (Rattus norvegicus) PubMed

 26885.

these observations support the participation of the IHy (incerto-hypothalamic area) and PLH (peduncular part of the lateral hypothalamus) NEI (neuropeptide glutamic acid isoleucine amide) as a modulating component of the HPT (Hypothalamic Pituitary-Thyroid Axis). (Rattus norvegicus) PubMed

 26886.

miR-29 to be a common mechanistic denominator for the vascular and pulmonary phenotypes in the IUGR offspring, providing a novel potential therapeutic target[mir-29] (Rattus norvegicus) PubMed

 26887.

this study provides a bidirectional role for GMF in executing dopaminergic neuronal death mediated by autophagy that is relevant to Parkinson's disease. (Rattus norvegicus) PubMed

 26888.

dysregulation of NgBR promotes vascular smooth muscle cells proliferation via Mitochondria-associated membranes disruption.[NgBR] (Rattus norvegicus) PubMed

 26889.

Transfection of somatolactotrope GH3 cells with pUC-shHNr increased apoptosis, suggesting that endogenous HNr plays a cytoprotective role in pituitary tumor cells. [HNr] (Rattus norvegicus) PubMed

 26890.

NEAT1 can induce neuropathic pain development in chronic constriction injury rats via regulating miR-381/HMGB1 axis.[NETA1] (Rattus norvegicus) PubMed

 26891.

the expression of miR-30c-5p positively correlated with the severity of allodynia.[miR30c] (Rattus norvegicus) PubMed

 26892.

Central injection of orexin A reduced hypothalamic neurokinin B expression. NKB. (Rattus norvegicus) PubMed

 26893.

serine-responsive transcript-2 may be involved in D-serine metabolism and/or function, and in the interactions between D-serine, NMDA receptor and neurexin-3alpha, in mammalian brain [serine-responsive transcript-2] (Rattus norvegicus) PubMed

 26894.

The severity of hypertension was greater in Ren2 mutant males than in females [REN2] (Rattus norvegicus) PubMed

 26895.

the oxytalan fiber system might regulate periodontal ligament function through tensional variations registered on the walls of the vascular structures [OXYTALAN] (Rattus norvegicus) PubMed

 26896.

drebrin-mediated postsynaptic accumulation of spikar regulates spine density, but is not involved in regulation of spine morphology (Rattus norvegicus) PubMed

 26897.

miR-146a is involved in the pathogenesis of diabetic peripheral neuropathy, and its expression level is closely related to the inflammatory responses that aggravate sciatic nerve injuries [MICRORNA-146A] (Rattus norvegicus) PubMed

 26898.

miR-369-5p--We identify DNMT3A as miR-369-5p target genes and demonstrate that inhibition of miR-369-5p expression augments cell proliferation by activating DNMT3A (Rattus norvegicus) PubMed

 26899.

Cocaine self-administration experiments revealed that Dnmt3a2 regulates drug cue memories that drive reinstatement of cocaine seeking and incubation of this phenomenon within the NAc shell. Dnmt3a2 does not influence cocaine's primary reinforcing effects. Dnmt3a2 mediates long-lasting cocaine cue memories in the NAc shell. Dnmt3a2. (Rattus norvegicus) PubMed

 26900.

These findings suggest that miR-130 knockdown alleviates infarction-induced myocardial injury by promoting PPAR-gamma expression (mir-130, rat). (Rattus norvegicus) PubMed

 26901.

siRNA interference of MST1 significantly inhibited apoptosis of in vitro cultured vascular smooth muscle cell[Mammalian ste20-like protein kinase 1] (Rattus norvegicus) PubMed

 26902.

these results suggested that MALAT1 may act as a competing endogenous RNA for miR-200c to upregulate the expression of HMGB1 and downregulate cardiac Ito. (Rattus norvegicus) PubMed

 26903.

DGCR5 suppresses neuronal apoptosis through directly binding and negatively regulating PRDM5.[lncRNA DGCR5] (Rattus norvegicus) PubMed

 26904.

pUR4 reduces TNF-alpha-induced beta1 integrin activation by depleting ECM FN, leading to a decrease in endothelial hyperpermeability and maintenance of monolayer integrity.[pUR4] (Rattus norvegicus) PubMed

 26905.

Our data show that miR-146a sponge gene therapy could effectively reduce miR-146a activity and attenuate neointimal formation in vein grafts, suggesting its potential therapeutic application for prevention of vein graft failure (Rattus norvegicus) PubMed

 26906.

Upregulation of long noncoding RNA RP4 exacerbates hypoxia injury in cardiomyocytes through regulating miR-939/Bnip3/Wnt/beta-catenin pathway [MiR-939] (Rattus norvegicus) PubMed

 26907.

These data provide new insights into the specific regulation of the |-Srgap2-Fam72a-| master gene.[Fam27a] (Rattus norvegicus) PubMed

 26908.

circAnks1a and VEGFB are regulators of neuropathic pain.[CircAnks1a] (Rattus norvegicus) PubMed

 26909.

The present work's main objective was to study the effect of different high fat diets on LXRs expression (in hypothalamus and liver), and lipid profile.[LXRA] (Rattus norvegicus) PubMed

 26910.

Long non-coding RNA CYTOR modulates pathological cardiac hypertrophy through miR-155-mediated IKBKE signaling. (Rattus norvegicus) PubMed

 26911.

the inhibition of Long noncoding RNAs WNT5A-AS can rescue the fate of neural stem cells.[WNT5A-AS] (Rattus norvegicus) PubMed

 26912.

A regulation loop among MATAL1, miR-194, and YAP1, which dynamically regulates the progression of acute pancreatitis, is reported.[MALAT1] (Rattus norvegicus) PubMed

 26913.

The key findings of the present study provide evidence emphasizing that lncRNA GAS5 functions as a competitive endogenous RNA of miR-135a-5p to increase expression of KCNQ3[LncRNA GAS5] (Rattus norvegicus) PubMed

 26914.

The results suggested that lncRNA RMRP negatively regulated miR613 in cardiac fibroblasts. Furthermore, miR613 was indicated to mediate the promoting effect of RMRP on cardiac fibroblast activation. [lncRNA RMRP, miR613] (Rattus norvegicus) PubMed

 26915.

protective effects of MALAT1 knockdown were flattened by miR-122 overexpression[MALAT1] (Rattus norvegicus) PubMed

 26916.

SAA1-mediated NOX4/ROS pathway could activate p38MAPK/NF-kappaB pathway, thereby contributing to the release of inflammatory factors in LPS-induced vascular smooth muscle cells.[SAA1] (Rattus norvegicus) PubMed

 26917.

miR-18a-5p may be a negative epigenetic regulator of 5-HT1AR.[miR18a] (Rattus norvegicus) PubMed

 26918.

results indicate that PNX may play a role in controlling glycemia by interacting with pancreatic beta cells [Phoenixin-14 ] (Rattus norvegicus) PubMed

 26919.

miR-9-5p: miR-9-5p over-expression can suppress the NF-kappaB signaling pathway through p50 downregulation, thus alleviating inflammation and thrombosis in DVT rats (Rattus norvegicus) PubMed

 26920.

Downregulation of circDNMT3B contributes to vascular dysfunction in diabetic retinas through regulating miR-20b-5p and BAMBI, providing a potential treatment strategy for diabetic retinopathy.[circRNA DNMT3B] (Rattus norvegicus) PubMed

 26921.

lncRNA DGCR5 suppresses neuropathic pain by sponging miR-330-3p and regulating PDCD4 expression. (Rattus norvegicus) PubMed

 26922.

lncRNA ZEB1-AS1 acts as a regulator of miR-141-3p/ZEB1 axis during lung fibrosis. ZEB1-AS1 as a potential therapeutic target for the prevention and treatment of pulmonary fibrosis. (Rattus norvegicus) PubMed

 26923.

CRMP2 regulated the low voltage-gated (T-type/CaV3.x) channels in sensory neurons. [CaV3.x] (Rattus norvegicus) PubMed

 26924.

it was demonstrated that Resveratrol has been demonstrated to prevent the development of cardiac injury induced by pulmonary embolism via modulating the expression of MALAT1 and further affect miR223p and NLRP3 (Rattus norvegicus) PubMed

 26925.

Results showed that the levels of GAS5, NR024118 and MRNR026574 were increased in the myocardium of hypertensive rats, suggesting that the three lncRNAs participate in the pathogenesis of hypertensive cardiac remodeling. [NR024118 and MRNR026574] (Rattus norvegicus) PubMed

 26926.

upregulation of miR-424 inhibited Rictor through Akt signaling in renal tissue of diabetic nephropathy rats and high-glucose-treated human glomerular mesangial cells.[mirn424] (Rattus norvegicus) PubMed

 26927.

Long non-coding RNA DLGAP1 antisense RNA 1 (DLGAP1-AS1) was highly expressed in ischemia-reperfusion (I/R), which was further confirmed by detection of expression in rat models of acute lower limb I/R. Notably, the treatment of siRNA against DLGAP1-AS1 led to the activation of the phosphoinositide 3-kinase/Akt pathway.[DLGAP1-AS1] (Rattus norvegicus) PubMed

 26928.

These results demonstrate that downregulation of LOC101928134 suppresses the synovial hyperplasia and cartilage destruction of Osteoarthritis (OA) rats via activation of JAK/STAT signaling pathway by upregulating IFNA1, providing a new candidate for the treatment of OA. (Rattus norvegicus) PubMed

 26929.

We verified the function and mechanism of lncRNA Gm2691 and provide evidence that lncRNA Gm2691 may play important role in ischemic reperfusion injury, and understanding the precise role of Gm2691 will undoubtedly shed new light on the clinical treatment. (Rattus norvegicus) PubMed

 26930.

LncRNA NEAT1 promotes extracellular matrix accumulation and epithelial-to-mesenchymal transition by targeting miR-27b-3p and ZEB1 in diabetic nephropathy[NEAT1] (Rattus norvegicus) PubMed

 26931.

lncRNA CDKN2B-AS1 may involve in the progression of cervical cancer and this regulation may be played through the miR-181a-5p/TGFbetaI axis. Our experimental data also suggested that the CDKN2B-AS1/miR-181a-5p/TGFbetaI axis may be a promising therapeutic target for cervical cancer or other cancers. (Rattus norvegicus) PubMed

 26932.

BMPR2 mutation in cardiomyocytes alters glucose-supported mitochondrial respiration and impairs cellular responses to insulin, including glucose and lipid uptake.[Insulin] (Rattus norvegicus) PubMed

 26933.

LncRNA HOTAIR can protect against myocardial infarction and hypoxia-induced cardiomyocytes apoptosis by sponging miR-519d-3p. (Rattus norvegicus) PubMed

 26934.

Lnc-NEAT1 is overexpressed in myocardial ischemia/reperfusion injury cells compared to normal myocardial cells. Downregulation of lnc-NEAT1 enhances cell proliferation while inhibits cell apoptosis (Rattus norvegicus) PubMed

 26935.

our study demonstrates the contributory effect of lncRNA HOTAIR on RIF by activating the Notch1/Jagged1 signaling pathway via inhibition of miR-124, whereas administration of PAE can alleviate the effects of HOTAIR on Renal interstitial Paeonol (RIF). (Rattus norvegicus) PubMed

 26936.

REDD1 depletion protects H9c2 cells against oxygen/glucose deprivation followed by reperfusion-induced injury through ameliorating oxidative stress, which is modulated by Akt/mTORC1/Nrf2 signaling.[REDD1] (Rattus norvegicus) PubMed

 26937.

The level of MEG3 significantly reduced in CFA-induced synovial tissues and Fibroblast-like synoviocytes (FLSs), whereas the NLRC5 levels were increased. Enforced expression of MEG3 may be responsible for the decreased level of NLRC5 and inflammatory cytokine level (Rattus norvegicus) PubMed

 26938.

IL-8 increased myocilin expression, Akt phosphorylation, FoxO3 dispersion throughout the cytoplasm, and reduced FoxO3 level. IL-8 decreased the expression of atrogin and MuRF1 and increased myotube length and diameter. (Rattus norvegicus) PubMed

 26939.

LncRNA MALAT1 promotes oxygen-glucose deprivation/reperfusion-induced cardiomyocyte injury by sponging miR-20b to enhance beclin1-mediated autophagy. (Rattus norvegicus) PubMed

 26940.

miR-449a-5p and Myc are involved in the hypoxic PAH by controlling metabolic pathways and phenotype of PASMCs leading to hyperproliferation. More importantly, miR-449a-5p/Myc axis, a novel molecular mechanism, is highlighted in the influence on mitochondrial function. [mir-449a] (Rattus norvegicus) PubMed

 26941.

overexpressed CPS1-IT alleviated Pulmonary arterial hypertension in obstructive sleep apnea by reducing IL-1beta expression, the mechanism of which was involved with inhibited HIF1 transcriptional activity and the NF-kappaB signaling pathway (Rattus norvegicus) PubMed

 26942.

over-expression of miR-374a-5p significantly attenuated brain injury and strongly inhibited the release of pro-inflammatory cytokines in neonatal rat hypoxic-ixchemic encephalopathy model [MIR374A new entry] (Rattus norvegicus) PubMed

 26943.

This study describes a novel mechanism, where miR-23a is an important cell type-specific regulator for asthma-associated airway wall remodeling[microRNA-23a] (Rattus norvegicus) PubMed

 26944.

Overexpression of HMGB1 diminished the effects of miR-129-5p on ameliorating oxidative stress and inflammatory response in rats with chronic heart failure. [miR-129-5] (Rattus norvegicus) PubMed

 26945.

lncRNA FAF interacted with FGF9 to regulate apoptosis of cardiomyocytes[FAF] (Rattus norvegicus) PubMed

 26946.

DCRF was targeted by miR-551b-5p in an AGO2-dependent manner and PCDH17 was the direct target of miR-551b-5p. [DCRF] (Rattus norvegicus) PubMed

 26947.

expression of miRNA-223 was negatively correlated with the level of FGD5-AS1[ FGD5-AS1] (Rattus norvegicus) PubMed

 26948.

Smad3 could inhibit SnoN expression and increase extracellular matrix deposition in NRK52E cells, to promote high glucose-induced renal tubular fibrosis.[SnoN] (Rattus norvegicus) PubMed

 26949.

the present study demonstrated that Siglec1 exerts its proinflammatory effects through increasing miR-1260, leading to decreased expression of IkappaBalpha.[mir1260 (Rattus norvegicus) PubMed

 26950.

FGF9 Is the Target of LncRNA FAF. [LncRNA FAF] (Rattus norvegicus) PubMed

 26951.

LncRNA-SULT1C2A regulates Foxo4 in congenital scoliosis by targeting rno-miR-466c-5p through PI3K-ATK signalling. (Rattus norvegicus) PubMed

 26952.

The Salusin-beta regulates Vascular calcification (VC) through activation of NAD(P)H/ROS-mediated Klotho downregulation, suggesting that salusin-beta may be a novel target for treatment of VC. (salusin-beta) (Rattus norvegicus) PubMed

 26953.

Novel Insights into MSK1 Phosphorylation by MRKbeta in Intracerebral Hemorrhage-Induced Neuronal Apoptosis. (Rattus norvegicus) PubMed

 26954.

Lysozyme elicits pain during nerve injury by neuronal Toll-like receptor 4 activation and has therapeutic potential in neuropathic pain. (Rattus norvegicus) PubMed

 26955.

MicroRNA-10-5p regulates differentiation of bone marrow mesenchymal stem cells into cardiomyocytes by targeting TBX5. (Rattus norvegicus) PubMed

 26956.

CircERCC2 ameliorated intervertebral disc degeneration by regulating mitophagy and apoptosis through miR-182-5p/SIRT1 axis. (Rattus norvegicus) PubMed

 26957.

Hexokinase II dissociation alone cannot account for changes in heart mitochondrial function, morphology and sensitivity to permeability transition pore opening following ischemia. (Rattus norvegicus) PubMed

 26958.

LncRNA Kcnq1ot1 renders cardiomyocytes apoptosis in acute myocardial infarction model by up-regulating Tead1. (Rattus norvegicus) PubMed

 26959.

Overexpression of miR-146b-5p Ameliorates Neonatal Hypoxic Ischemic Encephalopathy by Inhibiting IRAK1/TRAF6/TAK1/NF-alphaB Signaling. (Rattus norvegicus) PubMed

 26960.

MiR-593-5p promotes the development of hypoxic-induced pulmonary hypertension via targeting PLK1. (Rattus norvegicus) PubMed

 26961.

Influence of lncRNA HOTAIR on acute kidney injury in sepsis rats through regulating miR-34a/Bcl-2 pathway. (Rattus norvegicus) PubMed

 26962.

Long non-coding RNA small nucleolar RNA host gene 7 facilitates cardiac hypertrophy via stabilization of SDA1 domain containing 1 mRNA. (Rattus norvegicus) PubMed

 26963.

Role of microRNA-15a-5p in the atherosclerotic inflammatory response and arterial injury improvement of diabetic by targeting FASN. (Rattus norvegicus) PubMed

 26964.

Long non-coding RNA cardiac hypertrophy-associated regulator governs cardiac hypertrophy via regulating miR-20b and the downstream PTEN/AKT pathway. (Rattus norvegicus) PubMed

 26965.

MicroRNA15a5p induces pulmonary artery smooth muscle cell apoptosis in a pulmonary arterial hypertension model via the VEGF/p38/MMP2 signaling pathway. (Rattus norvegicus) PubMed

 26966.

MiR-146 regulates the repair and regeneration of intervertebral nucleus pulposus cells via Notch1 pathway. (Rattus norvegicus) PubMed

 26967.

LncRNA MALAT1 inhibits osteogenic differentiation of mesenchymal stem cells in osteoporosis rats through MAPK signaling pathway. (Rattus norvegicus) PubMed

 26968.

Overexpression of long noncoding RNA Malat1 ameliorates traumatic brain injury induced brain edema by inhibiting AQP4 and the NF-kappaB/IL-6 pathway. (Rattus norvegicus) PubMed

 26969.

Silencing lncRNA HOTAIR declines synovial inflammation and synoviocyte proliferation and promotes synoviocyte apoptosis in osteoarthritis rats by inhibiting Wnt/beta-catenin signaling pathway. (Rattus norvegicus) PubMed

 26970.

Role and mechanism of microRNA-548c-3p/c-Myb in myocardial infarction fibrosis in rats. (Rattus norvegicus) PubMed

 26971.

MicroRNA-146a Protects Against Ischemia/Reperfusion Liver Injury Through Inhibition of Toll-like Receptor 4 Signaling Pathway in Rats. (Rattus norvegicus) PubMed

 26972.

MicroRNA-449b-5p promotes the progression of osteoporosis by inhibiting osteogenic differentiation of BMSCs via targeting Satb2. (Rattus norvegicus) PubMed

 26973.

The suppression of miR-181 inhibits inflammatory responses of osteoarthritis through NF-kappaB signaling pathway. (Rattus norvegicus) PubMed

 26974.

Potential roles of lncRNA-Cox2 and EGR1 in regulating epidural fibrosis following laminectomy. (Rattus norvegicus) PubMed

 26975.

miR-129-5p Alleviates Neuropathic Pain Through Regulating HMGB1 Expression in CCI Rat Models. (Rattus norvegicus) PubMed

 26976.

Long noncoding RNA-dependent regulation of vascular smooth muscle cell proliferation and migration in hypertension. (Rattus norvegicus) PubMed

 26977.

LncRNA ANRIL knockdown ameliorates retinopathy in diabetic rats by inhibiting the NF-kappaB pathway. (Rattus norvegicus) PubMed

 26978.

Influence of lncRNA-MALAT1 on neuronal apoptosis in rats with cerebral infarction through regulating the ERK/MAPK signaling pathway. (Rattus norvegicus) PubMed

 26979.

The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells. (Rattus norvegicus) PubMed

 26980.

Influence of LncRNA UCA1 on glucose metabolism in rats with diabetic nephropathy through PI3K-Akt signaling pathway. (Rattus norvegicus) PubMed

 26981.

Influence of lncRNA ANRIL on neuronal apoptosis in rats with cerebral infarction by regulating the NF-kappaB signaling pathway. (Rattus norvegicus) PubMed

 26982.

LncRNA MALAT1 knockdown alleviates myocardial apoptosis in rats with myocardial ischemia-reperfusion through activating PI3K/AKT signaling pathway. (Rattus norvegicus) PubMed

 26983.

LncRNAs linc00311 and AK141205 are identified as new regulators in STAT3-mediated neuropathic pain in bCCI rats. (Rattus norvegicus) PubMed

 26984.

Targeting miR-106-3p facilitates functional recovery via inactivating inflammatory microglia and interfering glial scar component deposition after neural injury. (Rattus norvegicus) PubMed

 26985.

Effect of lncRNA MALAT1 on rats with myocardial infarction through regulating ERK/MAPK signaling pathway. (Rattus norvegicus) PubMed

 26986.

Human umbilical cord mesenchymal stem cell-derived exosomes act via the miR-1263/Mob1/Hippo signaling pathway to prevent apoptosis in disuse osteoporosis. (Rattus norvegicus) PubMed

 26987.

LncRNA MALAT1 promotes neuropathic pain progression through the miR1545p/AQP9 axis in CCI rat models. (Rattus norvegicus) PubMed

 26988.

Upregulation of lncRNA-NONRATT021203.2 in the dorsal root ganglion contributes to cancer-induced pain via CXCL9 in rats. (Rattus norvegicus) PubMed

 26989.

Identification, functional prediction, and key lncRNA verification of cold stress-related lncRNAs in rats liver. (Rattus norvegicus) PubMed

 26990.

Phosphodiesterase 7 Regulation in Cellular and Rodent Models of Parkinson's Disease. (Rattus norvegicus) PubMed

 26991.

Inhibition of microRNA-15 protects H9c2 cells against CVB3-induced myocardial injury by targeting NLRX1 to regulate the NLRP3 inflammasome. (Rattus norvegicus) PubMed

 26992.

Exercise Training-Induced PPARbeta Increases PGC-1alpha Protein Stability and Improves Insulin-Induced Glucose Uptake in Rodent Muscles. (Rattus norvegicus) PubMed

 26993.

NRF1-enhanced miR-4458 alleviates cardiac hypertrophy through releasing TTP-inhibited TFAM. (Rattus norvegicus) PubMed

 26994.

LncRNA UCA1 Suppresses the Inflammation Via Modulating miR-203-Mediated Regulation of MEF2C/NF-kappaB Signaling Pathway in Epilepsy. (Rattus norvegicus) PubMed

 26995.

miR125a attenuates BMSCs apoptosis via the MAPK-ERK pathways in the setting of craniofacial defect reconstruction. (Rattus norvegicus) PubMed

 26996.

Effects of lncRNA gm4419 on rats with hypertensive cerebral atherosclerosis through NF-kappaB pathway. (Rattus norvegicus) PubMed

 26997.

The glz2 gene is required for normal glucose response and plant growth and development. [GLZ2] (Arabidopsis thaliana) PubMed

 26998.

RETICULATA acts in a developmental pathway that involves CUE1 but does not include DOV1.[RETICULATA] [RE] (Arabidopsis thaliana) PubMed

 26999.

BRA is one of the genes that determine the balance between maintenance of proliferative activity in apical meristem and floral development in its peripheral region; such a balance is necessary for indeterminate inflorescence development.(BRA) (Arabidopsis thaliana) PubMed

 27000.

RPW8.1 and RPW8.2 are localized to the endomembrane system and accumulate to higher levels in response to application of exogenous salicylic acid. [RPW8.1 & RPW8.2] (Arabidopsis thaliana) PubMed

 27001.

Genetic analysis revealed that ssi4-induced H(2)O(2) accumulation and spontaneous cell death require RAR1, whereas ssi4-mediated stunting is dependent on SGT1b.[ssi4] (Arabidopsis thaliana) PubMed

 27002.

The effects of water deficits and heat, separately and together, on photosynthetis with abscisic acid metabolism, pigment composition and gene expression were investigated in ABP9 transgenic Arabidopsis.[ABP9] (Arabidopsis thaliana) PubMed

 27003.

AtCopeg1 originates from the AtCopia95 retrotransposon family, is sensitive to external hormones and abiotic stresses. It contains regulatory elements in its promoter region, and its expression is tissue-specific. [AtCopeg1] (Arabidopsis thaliana) PubMed

 27004.

DOQ, QKY, and ZET contribute to SUB-dependent organogenesis. [DOQ, QKY, and ZET] (Arabidopsis thaliana) PubMed

 27005.

The role of TRANSPORT INHIBITOR RESPONSE2 (TIR2) protein in development and gravitropism is reported.[TIR2] (Arabidopsis thaliana) PubMed

 27006.

Data showed that CK1A was highly expressed in flowers, stems and roots, but less in leaves and leafstalks. [CK1A] (Arabidopsis thaliana) PubMed

 27007.

RPW8.2 is induced by fungal invasion and targeted to the periphery of the fungal haustorium independently of salicylic acid signaling but requires functions of the actin cytoskeleton. [RPW8.2] (Arabidopsis thaliana) PubMed

 27008.

study suggest that GF14lambda may positively regulate the RPW8.2 resistance function and play a role in enhancing basal resistance in Arabidopsis.[RPW8.2 protein] (Arabidopsis thaliana) PubMed

 27009.

DRR1 is required at an early stage of pericycle cell activation to form lateral root primordia in response to both N-isobutyl decanamide and N-decanoyl-l-homoserine lactone. [DRR1] (Arabidopsis thaliana) PubMed

 27010.

KOD expression was sufficient to cause death in leaves or seedlings and to activate caspase-like activities.[KOD] (Arabidopsis thaliana) PubMed

 27011.

These results provide genetic evidence indicating that CDR3 is involved in the regulation of heavy metal resistance as well as seed development and flowering.[CDR3] (Arabidopsis thaliana) PubMed

 27012.

RPW8.2 is localized to both the plasma membrane and the extrahaustorial membrane. Adequate Expression and EHM-accumulation of RPW8.2 is required for activation of resistance to powdery mildew. [RPW8.2] (Arabidopsis thaliana) PubMed

 27013.

AtLRR84A is degraded in the lytic vacuole in ubiquitination-independent manner (AtLRR84A). (Arabidopsis thaliana) PubMed

 27014.

Roots of ahr1 seedlings grew downward and did not display hydrotropism. [ahr1] (Arabidopsis thaliana) PubMed

 27015.

expression of the AtR8 RNA responded negatively to hypoxic stress, and this regulation evidently differed from that of U6 snRNA. (Arabidopsis thaliana) PubMed

 27016.

The MKO1 gene plays an important role in the maintenance of the root apical meristem proliferative capacity and indeterminate root growth, which apparently acts independently of the SCR/SHR and WOX5 regulatory pathways. [MKO1] (Arabidopsis thaliana) PubMed

 27017.

Arabidopsis decanamide hypersensitive mutant1 (dhm1) shows increased sensitivity to N-isobutyl decanamide both in root and shoot systems, and suggest an important role of DHM1 gene in the regulation of cell division and differentiation. [dhm1] (Arabidopsis thaliana) PubMed

 27018.

Oxa1a and Oxa2 proteins function in embryo formation although at different developmental stages. [Oxa2] (Arabidopsis thaliana) PubMed

 27019.

AFL1 regulate various aspect of development through chromatin modification, particularly associated with histone H3 lysine 27 trimethylation in A. thaliana.[AFL1] (Arabidopsis thaliana) PubMed

 27020.

YUAN1 encodes a PHD zinc finger domain-containing protein and controls organ shape and size by restricting cell elongation. [YUAN1] (Arabidopsis thaliana) PubMed

 27021.

RPW8.2 is initially carried on VAMP721/722 vesicles, and that VAMP721, and to a much lesser extent VAMP722, are essential for transporting RPW8.2 to the extrahaustorial membrane and for the defense activity of RPW8.2 (RPW8.2). (Arabidopsis thaliana) PubMed

 27022.

The identification of a novel microRNA, miR10515, which targets superroot1 (SUR1), the gene encoding an indole glucosinolate biosynthetic enzyme, is reported.[miR 10515] (Arabidopsis thaliana) PubMed

 27023.

This study identified Arabidopsis miR778, a Pi-responsive miRNA, and its target gene Su(var) 3-9 homologs 6 (SUVH6) encoding a histone H3 lysine 9 (H3K9) methyltransferase.miRNA778] (Arabidopsis thaliana) PubMed

 27024.

COLDWRAP is derived from the repressed promoter of FLC and is necessary for the establishment of the stable repressed state of FLC by vernalization.[COLDWRAP] (Arabidopsis thaliana) PubMed

 27025.

The vernalization insensitivity caused by mutant COLDAIR was rescued by the ectopic expression of the wild-type COLDAIR. Our study reveals the molecular framework in which COLDAIR lncRNA mediates the PRC2-mediated repression of FLC during vernalization. (Arabidopsis thaliana) PubMed

 27026.

ADPR cyclase activity is regulated by nitric oxide.[ADPR cyclase] (Arabidopsis thaliana) PubMed

 27027.

AG-incRNA4 can associate with CLF to repress AG expression in leaf tissues through histone H3 lysine 27methylation 3-mediated repression and to autoregulate its own expression level.[AG-incRNA4] (Arabidopsis thaliana) PubMed

 27028.

Hrip1 is involved in affecting the flower bolting time and regulating endogenous JA biosynthesis and regulatory network to enhance resistance to insect.[Hrip1] (Arabidopsis thaliana) PubMed

 27029.

SOAR1 inhibits interactions of eIFiso4E, eIF4Es, eIF4A1, eIF4B2 and poly(A)-binding protein PAB6 with eIFiso4G1 and eIFiso4G2, thereby inhibiting eIFiso4F/mixed eIF4F assembly and repressing translation initiation.[eIFiso4F] (Arabidopsis thaliana) PubMed

 27030.

The data suggest that RPW8.2 is subject to adjustment by distinct and perhaps coordinated mechanisms for its localization and function via interaction with the multiple intramolecular trafficking signals, which should provide further insights into RPW8.2-activated, extrahaustorial membrane (EHM)-focused resistance against powdery mildew (RPW8.2). (Arabidopsis thaliana) PubMed

 27031.

lncRNA T5120 can promote nitrate assimilation and plant growth to improve nitrogen use efficiency.[lncRNA T5120] (Arabidopsis thaliana) PubMed

 27032.

PAT21 is protein S-acyl transferase and plays role in the both male and female gametogenesis.[PAT21] (Arabidopsis thaliana) PubMed

 27033.

attrappc11 mutants display accumulation of the plasma membrane resident proteins CESA6, BRI1 and PIP1;4 in aberrant intracellular compartments. This adds further insights into the functions of TRAPPIII as a regulators of post-Golgi/endosomal traffic.[AtTRAPPC11, TRAPPIII] (Arabidopsis thaliana) PubMed

 27034.

PIR1 and PIR2 play a positive role in abscisic acid (ABA) signaling via modulation of PP2CA stability. The findings provide insight into modulation of PP2C in ABA signaling in Arabidopsis. (Arabidopsis thaliana) PubMed

 27035.

miR396 is not only a marker of cell differentiation, but also an age signal for leaf development and phase change. Meanwhile, SWR1-C-mediated epigenetic regulation contributes to the age-dependent enhancement of miR396 expression and differential miR396 accumulation among leaves. [SWR1-C] (Arabidopsis thaliana) PubMed

 27036.

AtNSE1 and AtNSE3 are required for embryo pattern formation and maintenance of cell viability during Arabidopsis embryogenesis. (Arabidopsis thaliana) PubMed

 27037.

Inverse Correlation Between MPSR1 E3 Ubiquitin Ligase and HSP90.1 Balances Cytoplasmic Protein Quality Control. (Arabidopsis thaliana) PubMed

 27038.

Glucose-Regulated HLP1 Acts as a Key Molecule in Governing Thermomemory. (Arabidopsis thaliana) PubMed

 27039.

The SMO1 Family of Sterol 4alpha-Methyl Oxidases Is Essential for Auxin- and Cytokinin-Regulated Embryogenesis. (Arabidopsis thaliana) PubMed

 27040.

A Mitochondrial LYR Protein Is Required for Complex I Assembly. (Arabidopsis thaliana) PubMed

 27041.

Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance. (Arabidopsis thaliana) PubMed

 27042.

Identification of the Arabidopsis Calmodulin-Dependent NAD(+) Kinase That Sustains the Elicitor-Induced Oxidative Burst. (Arabidopsis thaliana) PubMed

 27043.

Knockout of Arabidopsis Serotonin N-Acetyltransferase-2 Reduces Melatonin Levels and Delays Flowering. (Arabidopsis thaliana) PubMed

 27044.

The novel protein CSAP accelerates leaf senescence and is negatively regulated by SAUL1 in the dark. (Arabidopsis thaliana) PubMed

 27045.

LPIAT, a lyso-Phosphatidylinositol Acyltransferase, Modulates Seed Germination in Arabidopsis thaliana through PIP Signalling Pathways and is Involved in Hyperosmotic Response. (Arabidopsis thaliana) PubMed

 27046.

PCH1 and PCHL Directly Interact with PIF1, Promote Its Degradation, and Inhibit Its Transcriptional Function during Photomorphogenesis. (Arabidopsis thaliana) PubMed

 27047.

A GDSL-type esterase/lipase gene, GELP77, is necessary for pollen dissociation and fertility in Arabidopsis. (Arabidopsis thaliana) PubMed

 27048.

ARABIDOPSIS NITRATE REGULATED 1 acts as a negative modulator of seed germination by activating ABI3 expression. (Arabidopsis thaliana) PubMed

 27049.

Docking of acetyl-CoA carboxylase to the plastid envelope membrane attenuates fatty acid production in plants. (Arabidopsis thaliana) PubMed

 27050.

Receptor kinase module targets PIN-dependent auxin transport during canalization. (Arabidopsis thaliana) PubMed

 27051.

A multidrug and toxic compound extrusion (MATE) transporter modulates auxin levels in root to regulate root development and promotes aluminium tolerance. (Arabidopsis thaliana) PubMed

 27052.

KRF is a novel transcription factor that is restricted to nuclear extracts isolated from keratinocytes and that binds to unique DNA sequences, which do not resemble any known consensus binding motif for transcription factors [KRF]. (Homo sapiens) PubMed

 27053.

The 14 kDa circulating ZIP from normal pregnancies suppressed components within the JAK/STAT pathway and induced suppressors of cytokine stimulation, SOCS2.[zeta inhibitor protein] (Homo sapiens) PubMed

 27054.

Zonulin upregulation seems to precede the onset of type 1 diabetes, providing a possible link between increased intestinal permeability and the development of autoimmunity in genetically susceptible individuals. (zonulin) (Homo sapiens) PubMed

 27055.

The transfection of hCGPx mediated by recombinant adenovirus could protect renal tubular epithelial cells from hypoxia-reoxygenation damage in vitro.[CGPx] (Homo sapiens) PubMed

 27056.

DRBP-120 is a double-stranded RNA (dsRNA)-binding protein, and it was detected in both the cytoplasm and the nucleus of HeLa cells associated with PKR.[DRBP-120] (Homo sapiens) PubMed

 27057.

Mimp expression reduces hepatocyte growth factor/scatter factor-induced proliferation and scattering by attenuating and altering the downstream signaling of met proto- concogene.[MIMP] (Homo sapiens) PubMed

 27058.

A new soluble factor, neutrophil activator of matrix metalloproteinases, secreted by unstimulated normal human peripheral blood neutrophils causes activation of cell- secreted promatrix metalloproteinase-2 & may have a role in cancer dissemination. NAM. (Homo sapiens) PubMed

 27059.

Isolation from cord blood a population of human cells that are similar to murine bone marrow-derived cells containg SSEA-4[SSEA-4] (Homo sapiens) PubMed

 27060.

genomic origins of matrix cell adhesion molecules-1 and -2 (Mat-CAM-1 and -2) are in the so-called nasopharnygocarcinoma (NPC) gene on chromosome 2, which is a putative oncogene[matrix cell adhesion molecules-1 and -2] (Homo sapiens) PubMed

 27061.

Haemosiderin is present in the urine of most patients with venous ulcers but not in ischaemia ulcers. (Homo sapiens) PubMed

 27062.

The activity of LINE-1 endonuclease (L1-EN)is determined more by structural parameters of the DNA target than by the nucleotide sequence(L1-EN). (Homo sapiens) PubMed

 27063.

A tumor marker elvated in 57 per cent of melanoma patients, predicting recurrene [TS90IC] (Homo sapiens) PubMed

 27064.

NMP22, nuclear matrix protein-22 in urine may be promising tool for screening bladder cancer [NMP22] (Homo sapiens) PubMed

 27065.

HERV-H-X is highly expressed in colon cancer, but its up-regulation is not related to env gene as it lacks an env ORF. [HERV-H-X] (Homo sapiens) PubMed

 27066.

Putative tumor suppressor YueF (GenBank Accession Number: BC00613) was previously identified as a novel HBx-interaction human protein and found to cause apoptosis in both tumor and non-tumor cell lines. (Homo sapiens) PubMed

 27067.

The serum titer of anti-Gal(0) IgG is much higher in rheumatoid arthritis than in mimicking diseases. Anti-cyclic citrullinated peptide remains the most specific biomarker for rheumatoid arthritis [Gal(0) IgG and cyclic citrullinated peptide]. (Homo sapiens) PubMed

 27068.

GCRG123, an active member of the L1 family, was up-regulated in human gastric signet-ring cell carcinoma[GCRG123] (Homo sapiens) PubMed

 27069.

Desiging peptides based on human WNT8 as potent inhibitors of signaling pathways. (Homo sapiens) PubMed

 27070.

Clinically distinct NP events attributed to SLE and occurring around the time of diagnosis were found to be associated with anti-P antibodies and LAC [ribosomal P protein and lupus anticoagulant]. (Homo sapiens) PubMed

 27071.

Immunohistochemically, reserve cell-like cells were positive for p63, cytokeratins 34BE12 and CK17 and were very weakly positive or negative for CAM5.2 [cytokeratin 17, cytokeratin 34BE12, and CAM5.2]. (Homo sapiens) PubMed

 27072.

Expression of anti-endothelial cell antibodies (AECA)might be a useful marker to predict the course of sarcoidosis [AECA]. (Homo sapiens) PubMed

 27073.

Nuclear coactivator p120alpha is essential for ligand-dependent stimulation of thyroid hormone receptors and PPARgamma, p120beta acted as a coactivating protein predominantly for androgen receptors[nuclear coactivator p120]. (Homo sapiens) PubMed

 27074.

The occurrence of echolucent carotid plaques was associated with oxLDL and systolic blood pressure, and oxLDL was associated with echolucent carotid plaques independently of systolic blood pressure.[oxLDL] (Homo sapiens) PubMed

 27075.

EBV-associated superantigen HERV-K18 Env could influence the genetic susceptibility to multiple sclerosis [HERV-K18] (Homo sapiens) PubMed

 27076.

intratubular LEEP-CAM expression is correlated with normal spermatogenesis and Sertoli cell function. In this context, it may contribute to adhesive cell-cell interactions. (Homo sapiens) PubMed

 27077.

the in vitro activity of point mutants in three L1-EN residues--Asp145, Arg155, Ile204--that are key for DNA cleavage, and determined their crystal structures. (Homo sapiens) PubMed

 27078.

RP215 monoclonal antibody identifies a new tumor marker in various human cancer cells[CA215}. (Homo sapiens) PubMed

 27079.

BerEP4 labeling is not reliable in superficial biopsies of basal cell carcinoma with squamoid features. (Homo sapiens) PubMed

 27080.

RGM249 might be a microRNA precursor gene involved in the differentiation and function upstream of a reverse transcriptase. (Homo sapiens) PubMed

 27081.

Isolation and characterization of HC1: a novel human DNA repair gene (Homo sapiens) PubMed

 27082.

There is an important correlation between serum levels of TSGF, CA-125 and endometrial cancer.[TSGF] (Homo sapiens) PubMed

 27083.

p19A downregulation in normal muscle differentiation suggests that in the cases where its gene is inappropriately re-activated it could affect muscle differentiation and contribute to disease pathology. (p19A) (Homo sapiens) PubMed

 27084.

The detection of MOC-31, HBME-1 and MOC-31-mRNA is helpful in distinguishing between cancer and reactive mesothelial cells in pleural effusions. [MOC-31] (Homo sapiens) PubMed

 27085.

[J1-31] In conclusion, down-regulation of J1-31 expression correlates with advancing grade of astrocytomas. The result suggests this protein plays some role in astrocytes that is progressively lost in malignant progression. (Homo sapiens) PubMed

 27086.

TCF8 cause late-onset Fuchs corneal dystrophy and interact with FCD4 on chromosome 9p [FCD4] (Homo sapiens) PubMed

 27087.

The expression of HA117 gene is high in initially diagnosed and non-remission patients with acute leukemia. Expression decreases with the improvement of the illness. [HA117] (Homo sapiens) PubMed

 27088.

X-linked lymphocyte-regulated protein pM1 (XMR), XLR, and SCP3 render tumor cells resistant to antitumor immunity [XLR, XMR] (Homo sapiens) PubMed

 27089.

miR-125 may not be related to the pathogenesis of colorectal cancer. [microRNA-125] (Homo sapiens) PubMed

 27090.

analysis of recycling of the Ca2+-activated K+ channel, KCa2.3, is dependent upon RME-1, Rab35/EPI64C, and an N-terminal domain [RME-1] (Homo sapiens) PubMed

 27091.

Enforced expression of SPIKE weakly induced apoptosis by promoting the mitochondrial cytochrome c release, the activation of caspase 3 and the caspase cleavage of both BAP31 and p130CAS.(SPIKE) (Homo sapiens) PubMed

 27092.

we identified a novel cyclic hendecapeptide that inhibits activation of complement factor B and the alternative pathway, which we named Complin (Homo sapiens) PubMed

 27093.

Findings suggest that STRO-1+ dental pulp stem cells consist of several interrelated subpopulations which can spontaneously differentiate into odontoblasts, osteoblasts, and chondrocytes.[STRO-1] (Homo sapiens) PubMed

 27094.

Potential of serum EPCA to serve as a significant predictor for subsequent cancer in isolated high-grade prostatic intraepithelial neoplasia.[EPCA:early prostate cancer antigen,human] (Homo sapiens) PubMed

 27095.

HTII-280 is likely to be a useful morphological and biochemical marker of human TII cells that may help to advance our understanding of various lung pathological conditions, including the origin and development of various lung tumors.[HTII-280] (Homo sapiens) PubMed

 27096.

Early prostate cancer antigen (EPCA) is a predictor of prostatic cancer in malignant lesions. Blood levels of EPCA are also predictive. (Homo sapiens) PubMed

 27097.

The data suggested that blocking PC-PLC function significantly inhibited lipopolysaccharide-induced IL-8 and MCP-1 production.[PC-PLC] (Homo sapiens) PubMed

 27098.

TAG-72 is absent from uterine decidua of normal, ectopic, and pathological pregnancies but present in the Fallopian tubes of ectopic pregnancies. TAG-72 in culture suppressed IL-15 and IFN-gamma expression in decidual CD1a+ cells. [TAG-72] (Homo sapiens) PubMed

 27099.

Serum early prostate cancer antigen (EPCA) has a role in disease progression in prostate cancer in a Chinese population [EPCA] (Homo sapiens) PubMed

 27100.

JL1 may be a prognostic marker for risk stratification in patients with Burkitt lymphoma (Homo sapiens) PubMed

 27101.

Complement component 4d may have a role in antibody-mediated rejection in liver allografts of patients with de novo immune hepatitis [C4d] (Homo sapiens) PubMed

 27102.

(Phosphatidylcholine-specific phospholipase C; PC-PLC) PC-PLC changes in cerebrospinal fluid reflect the overall receptor fluctuations in migraine. (Homo sapiens) PubMed

 27103.

The peptide-binding motif of HLA-DR8 shares important structural features with other type 1 diabetes-associated alleles. (Homo sapiens) PubMed

 27104.

Study demonstrates that mutation of Rnu2-8, one of the mouse multicopy U2 snRNA genes, causes ataxia and neurodegeneration. [Rnu2-8] (Homo sapiens) PubMed

 27105.

The trans-mobilization of non-autonomous retrotransposon SVA requires both L1 ORF1p and L1 ORF2p (L1 ORF1p and L1 ORF2p). (Homo sapiens) PubMed

 27106.

[oxidized low-density lipoprotein; ox-LDL] Plasma ox-LDL level and age are possible risk factors for carotid plaque among patients with acute ischemic stroke in the Chinese Han ethnic group. (Homo sapiens) PubMed

 27107.

The results suggested that T cells express mediatophore, which then plays a key role in mediating acetylcholine release, and that mediatophore expression is regulated by immunological stimulation. [Mediatophore protein, human] (Homo sapiens) PubMed

 27108.

suggest that there are polymorphisms in genes of the MHC that increase susceptibility to onychomycosis, particularly haplotype HLA-DR8 (Homo sapiens) PubMed

 27109.

CA 19.9 is the tumor marker of choice in pancreatic adenocarcinomas, with a clear relationship with tumor location, stage, and resectability. (Homo sapiens) PubMed

 27110.

expressional level of HNPs 1,2 and 3 were significantly higher and their distributions overlapped in cancerous tissues of gastric cancer patients [HNP-2] (Homo sapiens) PubMed

 27111.

[small heat shock protein 16.5; Hsp16.5] The flexible C-terminal tail of Hsp16.5 changes its orientation relative to the alpha-crystallin domain which enables alternative packing of dimers, thereby holding the assembly together. (Homo sapiens) PubMed

 27112.

Report lack of complement 4d (C4d) may indicate active remodeling of the aortic wall leading to aortic dissection. (Homo sapiens) PubMed

 27113.

Urinary BLCA-4 was highly specific in bladder cancer detection in the Chinese, with additional indicative value in muscle invasiveness detection.[BLCA-4] (Homo sapiens) PubMed

 27114.

In coronary artery disease patients with elevated baseline concentrations (>/=236 pmol/l) of MR-proANP, there was a significantly increased rate of all-cause death at 3 months. [MR-proANP] (Homo sapiens) PubMed

 27115.

BLCA-4 may not effect pro-angiogenic pathways in bladder cancer, it can however interact with IL-1alpha, IL-8, VEGF and MMP-9 to enhance tumourigenesis and tumour invasiveness.[BLCA-4 protein, human] (Homo sapiens) PubMed

 27116.

NDM29-dependent cell maturation induces amyloid precursor protein (APP) synthesis, leading to the increase of amyloid beta peptide (Abeta) secretion.[NDM29] (Homo sapiens) PubMed

 27117.

We found a novel HBsAg-binding protein (SBP), which is located at the human chromosome 14q32.33 (Homo sapiens) PubMed

 27118.

Concurrent acute T-cell mediated rejection in kidney transplant recipients with complement C4d+ acute antibody mediated rejection is an independent risk factor for graft failure. (Homo sapiens) PubMed

 27119.

These findings provide evidence that high expression level of BLCA-4 serves as a poor prognostic biomarker for human bladder cancer. (Homo sapiens) PubMed

 27120.

This study suggests that HNPs 1-3 promote tumor invasion and are potential indicators of disease progression in patients with bladder cancer. (Homo sapiens) PubMed

 27121.

The predominance of HLA-DR1 in the response to Art v 125-36 may be explained by subtle conformation changes of the peptide bound to DR1 compared to DR4.[HLA-DR1] (Homo sapiens) PubMed

 27122.

a critical involvement of phosphatidylcholine-specific phospholipase C in controlling molecular pathways responsible for maintaining a mesenchymal-like phenotype in metastatic breast cancer cells [phosphatidylcholine-specific phospholipase C] (Homo sapiens) PubMed

 27123.

). Our results provide convincing evidence for the first time that the expression of TAG-72 is up-regulated in human gliomas (Homo sapiens) PubMed

 27124.

Increased levels of sncRNA715 were found in demyelinated chronic human multiple sclerosis lesions, which contain Oligodendroglial Myelin Basic Protein (MBP) mRNA but lack MBP protein. (Homo sapiens) PubMed

 27125.

CA19-9 could be an important tool in the diagnosis of ovarian mature cystic teratoma.[CA19-9] (Homo sapiens) PubMed

 27126.

These results together suggest that P-2of the Epap-1 protein) inhibits viral entry through specific interaction at V3 loop region of the gp120. (Homo sapiens) PubMed

 27127.

the germinal centre protein human germinal centre-associated lymphoma regulates B-cell receptor signalling in B-lymphocytes which, without appropriate control, may lead to B-cell lymphoproliferation.[BCR] (Homo sapiens) PubMed

 27128.

Disruption of ASAR6 leads to the formation of bridged chromosomes, micronuclei, and structural instability of chromosome 6. (Homo sapiens) PubMed

 27129.

CA19-9 may be a prognostic factor for colorectal cancer patients with normal CEA levels.[CA19-9] (Homo sapiens) PubMed

 27130.

The expression of IL-18R complex on blood cells is perturbed in Alzheimer's disease and even more markedly in its preclinical state of mild cognitive impairment.[IL18R] (Homo sapiens) PubMed

 27131.

BerEP4 expression is common in selected sweat apparatus tumors (Homo sapiens) PubMed

 27132.

The present study reveals a novel regulation of RASSF1C and the potentially important role of RASSF1C in DNA damage responses via SCFbeta-TrCP and Mule.[SCFbeta-TrCP] (Homo sapiens) PubMed

 27133.

d-dimer and fibrinogen concentrations were significantly and positively, although weakly, associated with measures related to pulse wave analysis.[d-dimer] (Homo sapiens) PubMed

 27134.

The serum levels of PG II and G-17 were significantly higher in Changle than those in Fuan.[Gatrin 17] (Homo sapiens) PubMed

 27135.

This study demonstrates that protein kinase A (PKA) specifically phosphorylates Hsp90alpha at Thr90, and that the pThr9090-Hsp90alpha level is significantly elevated in proliferating cells. (Homo sapiens) PubMed

 27136.

The finding of a non-coding (nc) RNA (hereafter referred to as 51A) that maps in antisense configuration to intron 1 of the SORL1 gene, is reported.[51A ncRNA] (Homo sapiens) PubMed

 27137.

The human endogenous retrovirus type K type 1-encoded Np9 is a critical molecular switch of multiple signaling pathways regulating the growth of leukemia stem/progenitor cells (NP9). (Homo sapiens) PubMed

 27138.

Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk(uridine diphosphate-glucuronosyltransferase 2B) (Homo sapiens) PubMed

 27139.

these data support the involvement of EMT and mesenchymal-to-epithelial transition (MET) in the metastasis cascade and show that miR-200 is downregulated in the initial stages of stromal invasion but is restored at metastatic sites (Homo sapiens) PubMed

 27140.

SSEA-4 is expressed in a fraction of basaloid nonsmall cell lung cancer and is associated with poor prognosis [SSEA-4] (Homo sapiens) PubMed

 27141.

High SSEA-3 expression is associated with colorectal cancer. (Homo sapiens) PubMed

 27142.

Comprehensive characterization of the marginal and joint distributions for S100, HMB-45, and Melan-A across a large series of cutaneous melanomas revealed diversity of expression across this group of antigens. (HMB-45) (Homo sapiens) PubMed

 27143.

These results demonstrate the utility of the homogeneous assay for quantitative assessment of these endogenous cellular components in a 384-well plate in response to inhibition of Nedd8-activating enzyme (NAE) by MLN4924. (Homo sapiens) PubMed

 27144.

our study reveals a function for gamma-catenin in the regulation of mESC differentiation and has implications for human cancers in which gamma-catenin is mutated and/or aberrantly expressed. (Homo sapiens) PubMed

 27145.

LINE-1 ORF-1p promotes HepG2 cell proliferation and plays an important role in the resistance to chemotherapeutic drugs. (Homo sapiens) PubMed

 27146.

Heparin-binding epidermal growth factor-like growth factor (HE-EGF) suppresses claudin-3 expression in uterine luminal epithelium. (Homo sapiens) PubMed

 27147.

Taken together, we suggest that CM1 could be developed as a therapeutic target of lung cancer regardless of EGFR mutation status. (Homo sapiens) PubMed

 27148.

These findings suggest that ceramide may play an important role in sAPPalpha processing by modulating PKC activity.[sAPP alpha] (Homo sapiens) PubMed

 27149.

The cloned A3IP gene encodes A3IP, a novel ataxin-3 interacting protein. [A3IP] (Homo sapiens) PubMed

 27150.

the effects of Ramadan fasting on serum concentrations of immunoglobulin (Ig)G and IgM, and salivary IgA concentrations, were investigated.[IgM, IgG, IgA] (Homo sapiens) PubMed

 27151.

Electron microscopy (EM), differential scanning microcalorimetry (DSC) and fluorescence were used for structural analysis of the hIgG2.[IgG2] (Homo sapiens) PubMed

 27152.

Data suggest that changes in OGA and OGT (O-linked N-acetylglucosamine transferase) expression are correlated with cancer prognosis. [REVIEW] [OGA, O-GlcNAcase; peptide O-linked N-acetylglucosamine-beta-N-acetylglucosaminidase] (Homo sapiens) PubMed

 27153.

High TSGF expression is associated with lymph node metastasis in colon cancer. (Homo sapiens) PubMed

 27154.

Serum SPan-1 level was identified as an independent factor related to poor prognosis of stage IV gastric cancer patients who underwent palliative gastrectomy. [SPan-1] (Homo sapiens) PubMed

 27155.

genetic association studies in Han population in China: Data suggest that AZFc/DAZ1 duplications underlie genetic predisposition of Y-chromosome haplogroup K* to spermatogenic impairment (azoospermia/oligospermia). [AZFc; azoospermia factor c] (Homo sapiens) PubMed

 27156.

the depressed antiviral activity and decreased frequency of Vgamma9Vdelta2-T cells may likely account for the high susceptibility to microbial infection in neonates.[Vgamma9, Vdelta2] (Homo sapiens) PubMed

 27157.

The proliferation of human adipose-derived stem cells correlated with the concentration of PDGF-AB, BB and TGF-beta1.[PDGF-AB, PDGF-BB] (Homo sapiens) PubMed

 27158.

The results demonstrate that individuals with global hypomethylation measured in BLCA-4 repeats in blood leukocyte DNA have an increased risk for bladder cancer (BLCA-4). (Homo sapiens) PubMed

 27159.

LFA-1 acts as recognition receptor in the phagocytosis portals of macrophages for engulfment of apoptotic neutrophils. (Homo sapiens) PubMed

 27160.

(Hs2st) ERK signaling is activated in corpus callosum in transgenic mice lacking Hs2st (and Hs6st1). (Homo sapiens) PubMed

 27161.

69% of human glioblastoma multiforme specimens, but not normal brain tissue, were SSEA-4+ and correlated with high-grade astrocytoma. [Stage-specific embryonic antigen-4] (Homo sapiens) PubMed

 27162.

Elevated concentration of serum CA 19-9 is associated with poorer overall survival in patients with gastric cancer. (Homo sapiens) PubMed

 27163.

The results obtained show apo-LF performs as a normoxic mimetic of hypoxia, capable of stabilizing HIF-1alpha.(apolactoferrin) (Homo sapiens) PubMed

 27164.

The levels of circulating and local renin-angiotensin-aldosterone system expressions were different in atrial fibrillation patients with different types of mitral valvular diseases.[Angiotensin II] (Homo sapiens) PubMed

 27165.

these results revealed that 14-3-3beta regulates the proliferation of astrocytes and glioma cells through the GSK3beta/beta-catenin signaling pathway. (Homo sapiens) PubMed

 27166.

Our results demonstrate that the FAMLF gene is expressed in an acute myelogenous leukemia patient but not in healthy controls, suggesting its association with AML. (Homo sapiens) PubMed

 27167.

A report on the down-regulation of microRNA-31-microRNA-720 pathway in the plasma and endothelial progenitor cells from patients with coronary artery disease (microRNA-720). (Homo sapiens) PubMed

 27168.

The expression of osteoprotegerin is locally increased in carotid atherosclerotic lesions of symptomatic compared to asymptomatic patients (Homo sapiens) PubMed

 27169.

sub-cellular localization of HSMAR2 is dependent on the host cell type and that HSMAR2 is cytotoxic when overexpressed in HeLa cells. (Homo sapiens) PubMed

 27170.

This study showed that PI3K/Akt/mTOR signaling may play a critical role in protecting epithelial cells from damage during mucosal fungal infections independent of NF-kappaB or MAPK signaling.[Akt] (Homo sapiens) PubMed

 27171.

Angiotensin II suppresses RECK, but induces matrix metalloproteinases both in vivo and in vitro.[Angiotensin II] (Homo sapiens) PubMed

 27172.

a conformation coupling initiated during voltage-perturbation by Ca2+-binding to the pore of the VGCC and prior to permeation, triggers synchronous release of channel-tethered vesicles through dynamic intra-membrane interactions with Sx1A. (Homo sapiens) PubMed

 27173.

Results indicate that actin cytoskeleton is one of the upstream regulators of Hippo signaling: [Hippo] (Homo sapiens) PubMed

 27174.

Children with the HLA haplotype DR3-DQ2, especially homozygotes, were found to be at high risk for celiac disease autoimmunity and celiac disease early in childhood.[HLA-DQ2] (Homo sapiens) PubMed

 27175.

ACA is an essential regulator of the genes involved in maintaining hematopoiesis. [ACA protein] (Homo sapiens) PubMed

 27176.

ACA signaling via PI3K/Akt/mTor induces sustained de-differentiation of human blood progenitor cells leading to generation of ACA pluripotent stem cells. [ACA protein] (Homo sapiens) PubMed

 27177.

An intestinal trefoil factor-specific receptor appears to be present on the three types of intestinal epithelial cells.[ITFR] (Homo sapiens) PubMed

 27178.

Ischemic hepatocyte C4d levels were similar in both positive and negative HLA donor-specific antibody (DSA) patients undergoing liver transplantation. There was no association between anti-HLA DSA and preservation-reperfusion injury and C4d. [C4d] (Homo sapiens) PubMed

 27179.

CAI2 contributes to the paradoxical overexpression of p16 in neuroblastoma, where CAI2 may offer a useful biomarker of high-risk disease. (Homo sapiens) PubMed

 27180.

The mechanisms by which Angiotensin II affected cell migration in AT1R-positive MDA-MB-231 human breast cancer cells, was investigated.[Angiotensin II] (Homo sapiens) PubMed

 27181.

The X-DING-CD4 gene was more sensitive to HIV-1 than rIFN-alpha stimulation. [X-DING-CD4 gene] (Homo sapiens) PubMed

 27182.

The abundance of HERV-K gag message is significantly higher in prostate cancer cases than controls and was associated with increased plasma interferon-gamma. [HERV-K-gag] (Homo sapiens) PubMed

 27183.

long noncoding ribonucleic acid RCCRT1 is correlated with prognosis and promotes cell migration and invasion in renal cell carcinoma [RCCRT1] (Homo sapiens) PubMed

 27184.

The results illustrate one possible glycosylation pathway where alpha-DG function is regulated by opposing actions of HNK-1ST and like-acetylglucosaminyltransferase(LARGE). (HNK-1 sulfotransferase) (Homo sapiens) PubMed

 27185.

Results show that ERDR1 is a stromal-derived factor that promotes cancer cell survival in vitro and in an experimental metastasis model. [Erdr1] (Homo sapiens) PubMed

 27186.

Elevated Stro-1+ bone marrow cell profile may be a useful prognostic indicator for uncemented total hip arthroplasty patients.[Stro-1] (Homo sapiens) PubMed

 27187.

These data indicate that DUF1220 protein domain (CON1) dosage has an autism spectrum disorder-wide effect and, as such, is likely to be a key component of a major pathway underlying autism spectrum disorder severity (Homo sapiens) PubMed

 27188.

the 28S ribosomal DNA (RN28S1) gene is a novel fusion partner of the B-cell leukemia/lymphoma 11B gene, the immunoglobulin kappa variable 3-20 gene and the component of oligomeric Golgi complex 1 gene in hematologic malignancies. [RN28S1] (Homo sapiens) PubMed

 27189.

Study showed that LINE-1 ORF-1p enhanced ETS-1 transcriptional activity and increased expression of downstream genes of ETS-1. Interaction between ETS-1 and LINE-1 ORF-1p was identified by immunoprecipitation assays. [LINE-1 ORF-1p] (Homo sapiens) PubMed

 27190.

WNK4 inhibits SNARE formation of syntaxin 13 with VAMP2. [syntaxin 13] (Homo sapiens) PubMed

 27191.

This study provides the first prognostic cancer gene signature derived from a murine model of nmMLCK-associated lung inflammation. Activation of nmMLCK-involved pathways contributes to tumor growth and progression in human cancers. (Homo sapiens) PubMed

 27192.

fibronectin extra domain A (Fn(EDA)) is an endogenous TLR4 ligand markedly elevated in the circulation and lesional skin biopsies from patients with scleroderma, as well as in mice with experimentally induced cutaneous fibrosis.[FnEDA] (Homo sapiens) PubMed

 27193.

We conclude that miR-BART20-5p and miR-BART8 cause progression of nasal NK-cell lymphomas through inhibition of the IFN-gamma-STAT1 pathway. (Homo sapiens) PubMed

 27194.

Serum CCSA-2 not only may be a potential biomarker using in screening and surveillance of CRC, but also may be an independent prognostic marker for CRC patients [CCSA-2] (Homo sapiens) PubMed

 27195.

Results identify a critical role for 14-3-3tau in promoting breast cancer metastasis, in part through binding to and inhibition of RhoGDIalpha, a negative regulator of Rho GTPases and a metastasis suppressor. [14-3-3tau] (Homo sapiens) PubMed

 27196.

LINE-1 open reading frame 1 protein is a surprisingly broad, yet highly tumor-specific, antigen.[LINE-1 orf1p] (Homo sapiens) PubMed

 27197.

Glypican-3 is the only oncofetal antigen that showed comparable high diagnostic accuracy as PIVKA-II in diagnosing HCC among Egyptian patients. (Homo sapiens) PubMed

 27198.

show here that IL1A, IL1B and IL1F7 regulatory regions come in close proximity in LPS stimulated cells but not in resting human monocytes [IL36] (Homo sapiens) PubMed

 27199.

REST is targeted to the HAR1 locus by specific DNA regulatory motifs, resulting in potent transcriptional repression.[HAR1] (Homo sapiens) PubMed

 27200.

Immunocytochemistry using HBME-1, CK-19 and the Ki-67 proliferative index increased the diagnostic accuracy of FNA in the FN/SFN category of the Bethesda System, which may help to distinguish lesions in this category (Homo sapiens) PubMed

 27201.

Human cancer cells with enhanced expression of Le(Y) were shown to acquire docetaxel-resistance, indicating the possible involvement of glycoconjugates in the drug-resistance. [Lewis Y antigen] (Homo sapiens) PubMed

 27202.

Our data suggested that lncRNA-HMlincRNA717 may play crucial roles during cancer occurrence and progression and may be a new potential biomarker of early gastric cancer (Homo sapiens) PubMed

 27203.

HLA-DR9 and DR14, but not HLA-B58, are associated with hypersensitivity reaction by allopurinol when administered in patients with hematologic malignancy prior to chemotherapy.[HLA-DR9, HLA-DR14] (Homo sapiens) PubMed

 27204.

Using the renal carcinoma tissue microarray and renal tissues, the study found that the protein expression of nonEN2 in kidney tumor tissues was significantly lower than that in kidney normal tissues (p < 0.05), so was in renal cell lines. [nonEN2] (Homo sapiens) PubMed

 27205.

YueF overexpression led to increased protein levels of p53 and p21; the levels of cyclin D1 and pRb were decreased, resulting in reduced cell growth and G1/S cell-cycle arrest. (Homo sapiens) PubMed

 27206.

The aim was to evaluate the effect of STRO-1 cell sorting and Wnt3a treatment on cell behavior of human periodontal ligament cells.[STRO-1] (Homo sapiens) PubMed

 27207.

Overexpression of GCRG213p is common in both primary gastric cancer and lymph node metastasis (GCRG213). (Homo sapiens) PubMed

 27208.

an imbalance between activin-A and follistatin contributes to the pathogenesis of cigarette smoke-induced inflammation and COPD [activin-A] (Homo sapiens) PubMed

 27209.

A cross sectional study to determine whether anti-salivary gland protein 1 (SP1) antibodies were identified in particular subgroups of patients with Sjogren syndrome are reported.[SP1] (Homo sapiens) PubMed

 27210.

These results indicate that CA15-3, CA125, CEA, and TSGF in nipple discharge can serve as novel biomarkers in the diagnosis and prognosis of breast cancer. [TSGF] (Homo sapiens) PubMed

 27211.

actin modulation was involved in the ERDR1-enhanced NK cell cytotoxicity (Homo sapiens) PubMed

 27212.

Hsp74, a potential bladder cancer marker, has direct interaction with keratin 1. (Homo sapiens) PubMed

 27213.

The human phosphopantetheinyl transferase are required for the posttranslational modification of carrier proteins involved in diverse metabolic pathways. (phosphopantetheinyl transferase ) (Homo sapiens) PubMed

 27214.

Microarray analysis show aberrant expression of HOTAIR and newly identified lncRNA-422 in patients with colorectal cancer suggesting their participation in carcinogenesis. [lncRNA-422]. (Homo sapiens) PubMed

 27215.

The coated combination of TnC and TnR appeared to regulate neural differentiation signaling through integrin alpha7 and alpha9beta1 in bone marrow-derived human mesenchymal stem cells.[Tenascin R] (Homo sapiens) PubMed

 27216.

Suggest that Gla-rich protein (GRP) is a new player in mineralization competence of extracellular vesicles possibly associated with the fetuin-A-MGP calcification inhibitory system in the cardiovascular system. (Homo sapiens) PubMed

 27217.

The CD8 antiviral factor (CAF) can suppress HIV-1 transcription from the long terminal repeat (LTR) promoter in the absence of elements upstream of the CATATAA box (Homo sapiens) PubMed

 27218.

Post-treatment CA 19-9 and normalized post-operative CA 19-9 (R0 and R1 resected tumors) were independent factors associated with OS and DFS, however, initial CA 19-9 level was not statistically significant in multivariate analysis. (Homo sapiens) PubMed

 27219.

The aim of this study was to demonstrate the role of fused-in-glioblastoma-c-ros-oncogene1 (FIG-ROS) fusion gene in Intrahepatic cholangiocarcinoma.[FIG-ROS] (Homo sapiens) PubMed

 27220.

HBME-1, Galectin-3, Cytokeratin-19 and CD56 were used alone or in panels in a series of papillary thyroid carcinoma (PTC) and thyroid tumors of uncertain malignant potential.[HBME-1] (Homo sapiens) PubMed

 27221.

In the study the C4d urinary excretion in patients <1 year and >1 year post kidney transplantation were 4.6 +/- 7.5 and 5.3 +/- 7.9 ng/mgCr, respectively. Complement C4d (Homo sapiens) PubMed

 27222.

our data demonstrate that CiC expression is activated during ER stress through the binding of ATF6alpha and XBP1 to an UPRE element located in the proximal promoter of Cic gene (Homo sapiens) PubMed

 27223.

findings indicate a novel antiviral mechanism mediated by influx of soluble X-DING-CD4, its signaling to promote self-amplification and functional duality as an endogenous innate immunity effector and exogenous factor regulating gene expression in bystander cells [X-DING-CD4] (Homo sapiens) PubMed

 27224.

The results suggested that HA117 may be a factor exerting an anti-differentiation or or anti-maturation role in the genesis of Hirschsprung's disease (Homo sapiens) PubMed

 27225.

our data demonstrated CADM1-AS1 is a new tumor suppressor in clear cell renal cell carcinoma which regulates cell proliferation, apoptosis and migration via the expression pattern of "CADM1-AS1/CADM1 mRNA gene pairs". (Homo sapiens) PubMed

 27226.

TSLC1-AS1 was a tumor suppressor of glioma and a mediator of TSLC1 expression[as1]. (Homo sapiens) PubMed

 27227.

The results indicate that BCAM-AKT2 expression is a new mechanism of AKT2 kinase activation in high-grade serous ovarian carcinoma.[BCAM-AKT2] (Homo sapiens) PubMed

 27228.

The SDS depression score was positively associated with serum IAP levels in colorectal cancer patients. After the depression symptoms were treated, the IAP levels dramatically decreased. IAP. (Homo sapiens) PubMed

 27229.

TERMINATOR (chromsome 1) is specifically expressed in undifferentiated pluripotent stem cells. Its downregulation upregulated 506 genes and downregulated 185 genes involved in cell-cell interactions and chromatin remodeling for pluripotency (TERMINATOR). (Homo sapiens) PubMed

 27230.

Downregulation of miR-720 might be considered to be a potentially important molecular treatment strategy for early stage colorectal cancer patients. (Homo sapiens) PubMed

 27231.

This study investigated the correlations of ischemia-modified albumin with sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation (APACHE) scores in inpatients admitted for colorectal surgery.[IMA] (Homo sapiens) PubMed

 27232.

We also found that this locus displays asynchronous replication that is coordinated with other random monoallelic genes on chromosome 15. We have named this locus ASynchronous replication and Autosomal RNA on chromosome 15, or ASAR15 (Homo sapiens) PubMed

 27233.

serum CA 19-9 levels have an independent prognostic role in patients with resectable hepatocellular carcinoma. (Homo sapiens) PubMed

 27234.

NMR and modeling-based data on the molecular recognition features of synthetic Tn antigen - bearing glycopeptides by macrophage galactose-type lectin are presented. [macrophage galactose-type lectin] (Homo sapiens) PubMed

 27235.

Results identified Shad1, a novel noncoding RNA that colocalizes with YB-1 to P-bodies and stress granules. Its expression was shown to correlate with that of YB-1 and whose inhibition leads to an increase in cell proliferation. [Shad1] (Homo sapiens) PubMed

 27236.

PIF is involved in pathological pregnancies characterized by insufficient or excessive trophoblast invasion. [Preimplantation factor (PIF), human] (Homo sapiens) PubMed

 27237.

LEIGC long non-coding RNA acts as a tumor suppressor in gastric carcinoma by inhibiting the epithelial-to-mesenchymal transition (Homo sapiens) PubMed

 27238.

the menstrual cycle does not have a significant impact on CA 72-4 values.[CA 72-4] (Homo sapiens) PubMed

 27239.

NRH2 enhanced the ratio of Bax/Bcl-2 by promoting the expressions of proNGF, sortilin and p75NTR, thereby inducing brain cell apoptosis. [NRH2] (Homo sapiens) PubMed

 27240.

he molecular recognition of PTS1 cargo proteins by Pex5p [PTS1] (Homo sapiens) PubMed

 27241.

miR-1280 is a tumor suppressor in melanoma via inhibition of the Src signaling pathway. [miR1280] (Homo sapiens) PubMed

 27242.

Data indicate that microRNA miR218-5p negatively regulates trefoil factor 1 (TFF1) in an extracellular signal-regulated kinases Erk1/2-dependent manner: [miR218-5p] (Homo sapiens) PubMed

 27243.

Integrin alpha4beta7 expression increases HIV susceptibility, but the mechanism is not through promoting HIV binding to target cells.[Integrin alpha4beta7] (Homo sapiens) PubMed

 27244.

miR-181a mediates TGF-beta-induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancer. [miR-181a] (Homo sapiens) PubMed

 27245.

BiP facilitates Sec61 channel closure (i.e. limits ER Ca(2+) leakage) via the Sec61 channel with the help of ERj3 and ERj6 (Homo sapiens) PubMed

 27246.

Study describes the identification of a novel pair of ZNF genes, altered expression of ZNF465/466 in patients' samples and its absence in healthy donor haematopoietic samples indicate that ZNF465 is overexpressed in early myeloid disease [ZNF465, ZNF466] (Homo sapiens) PubMed

 27247.

miR-101 functions as a growth-suppressive miRNA in H. pylori related GC, and that its suppressive effects are mediated mainly by repressing SOCS2 expression. (Homo sapiens) PubMed

 27248.

Hippo pathway is deregulated in many soft-tissue sarcomas, resulting in elevated expression of the effector molecule Yes-Associated Protein [hippo] (Homo sapiens) PubMed

 27249.

MiRNA-320 in the human follicular fluid is associated with embryo quality in vivo and affects mouse embryonic development in vitro (Homo sapiens) PubMed

 27250.

Higher LINE1 methylation levels measured prior to cancer diagnosis may be a biomarker of future RCC risk among male smokers.[LINE1] (Homo sapiens) PubMed

 27251.

Hippo-YAP/ERK/AKT regulatory network modulates breast cancer cell contact inhibition of proliferation, cell cycle progression and maintenance of tumor initiating cells. (Homo sapiens) PubMed

 27252.

These results suggest that miR-1 has a tumor-suppressive effect on the development and progression of ESCC. (Homo sapiens) PubMed

 27253.

Increased expression of JAG2, a target of miR-1280, is associated with high metastatic dissemination at diagnosis and a poor outcome in medulloblastoma. (Homo sapiens) PubMed

 27254.

the C-terminus of Sororin functions as an anchor binding to SA2, which facilitates other conserved motifs on Sororin to interact with other proteins to regulate sister chromatid cohesion and separation.[SA2] (Homo sapiens) PubMed

 27255.

3' exons of neurotrophic tyrosine kinase receptor type 1 (NTRK1, encoding TrkA) are fused to 5' exons of the genes that are highly expressed in neuronal tissues, neurofascin (NFASC) and brevican (BCAN).[NTRK1-NFASC, NTRK1-BCAN] (Homo sapiens) PubMed

 27256.

Data suggest that plasma humanin levels are up-regulated in men (but not women) with uncomplicated type 1 diabetes as compared to healthy control subjects. [humanin; HN, HNGF6A] (Homo sapiens) PubMed

 27257.

miR-218 suppresses the proliferation, migration and invasion of LoVo colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathway and MMP9 (Homo sapiens) PubMed

 27258.

Downregulation of miR-518a-3p activates the NIK-dependent NF-kappaB pathway in colorectal cancer (Homo sapiens) PubMed

 27259.

FCGR2B2 compartments participate in the transcytosis of maternal IgG across the human placental endothelium (Homo sapiens) PubMed

 27260.

miR-30c inhibited colon cancer cells via targeting ADAM19. (Homo sapiens) PubMed

 27261.

MIRN10 microRNA. Data indicate that miR-10a is decreased in the inflamed mucosa of IBD and downregulates mucosal inflammatory response through inhibition of IL-12/IL-23p40 and NOD2 expression, and blockade of Th1/Th17 cell immune responses (Homo sapiens) PubMed

 27262.

LncRNA PEG10 is upregulated in esophageal cancer tissues, and its downregulation inhibits proliferation and invasion, and promotes apoptosis in esophageal cancer cells. [LncRNA PEG10] (Homo sapiens) PubMed

 27263.

mirn199 microRNA, human. miR-199a-5p/HK2 reprograms the metabolic process in liver cancer cells and provides potential prognostic predictors for liver cancer patients (Homo sapiens) PubMed

 27264.

We show that pHAR-associated schizophrenia genes are under stronger selective pressure compared with the other schizophrenia genes (Homo sapiens) PubMed

 27265.

results suggest that IL-17A rs4711998, IL-17A rs2275913, and IL-17F rs763780 polymorphisms do not contribute to HBV-related hepatocellular carcinoma susceptibility independently (Homo sapiens) PubMed

 27266.

miR-103a-3p regulates the osteogenic differentiation and proliferation of human adipose tissue-derived stromal cells by direct targeting of CDK6 and DICER1 partly. [miR-103a-3p] (Homo sapiens) PubMed

 27267.

A subunit composition of AMPK (alpha2beta2gamma1) is preferred for colorectal cancer cell survival, at least in part, by stabilizing the tumor-specific expression of PGC1B. [AMPK beta2] (Homo sapiens) PubMed

 27268.

Overexpression of miR-138 inhibited cell proliferation by directly suppressing the expression of Bag-1. (Homo sapiens) PubMed

 27269.

The ADAM12-L 3'UTR is a direct target of miR-29 and miR-200 family members. (Homo sapiens) PubMed

 27270.

The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines (Homo sapiens) PubMed

 27271.

miR-218 targets survivin and regulates resistance to chemotherapeutics in breast cancer (Homo sapiens) PubMed

 27272.

MicroRNA-153 inhibits osteosarcoma cells proliferation and invasion by targeting TGF-beta2 (Homo sapiens) PubMed

 27273.

Under optimal conditions, the immunosensor exhibited a wide linear response to CA199 ranging from 0.001 to 12 U/mL with a low detection limit of 0.0005 U/mL. (Homo sapiens) PubMed

 27274.

miR-486-5p may thus be useful for evaluating prognosis and may provide a novel target treatment in patients with GC. (Homo sapiens) PubMed

 27275.

mir-124 may play key roles in the progression of lung cancer and the down-regulated expression of miR-124 may be independently associated with shorter overall and disease-free survival of patients. (Homo sapiens) PubMed

 27276.

BRBP1-TAT-KLA inhibited the formation of both large and micro-metastases, while TAT-KLA alone failed to significantly reduce micro-metastases in the breast cancer brain metastasis mice (Homo sapiens) PubMed

 27277.

Suggest that lncRNA-ATB, a mediator of TGF-beta signaling, could predispose breast cancer patients to EMT and trastuzumab resistance. (Homo sapiens) PubMed

 27278.

the activity of RPF151 against MDA-MB-231 and its lower pungency suggest that it may have a relevant role in cancer therapy. (Homo sapiens) PubMed

 27279.

MiR-101 sensitizes human nasopharyngeal carcinoma cells to radiation by targeting stathmin 1 (Homo sapiens) PubMed

 27280.

A12308G, a polymorphic mutation in V-loop tRNA(Leu(CUN)), could be considered as pathogenic mutation in colorectal cancer. (Homo sapiens) PubMed

 27281.

these data demonstrate that miR-15a/16 induced autophagy contribute partly to their inhibition of cell proliferation and enhanced chemotherapeutic efficacy of CPT. (Homo sapiens) PubMed

 27282.

Expression of dehydroepiandrosterone-enhanced dual specificity protein phosphatase leads to prevention of diet-induced and genetic (db/db) obesity. [Dehydroepiandrosterone-enhanced dual specificity protein phosphatase] (Homo sapiens) PubMed

 27283.

Data identify a lncRNA (Khps1) that activates the expression of SPHK1 by targeting its promoter in an E2F1-dependent manner, promotes cell proliferation and restricts E2F1-induced apoptosis. [KHPS1] (Homo sapiens) PubMed

 27284.

lncRNA RGMB-AS1 was upregulated in non-small cell lung cancer. (Homo sapiens) PubMed

 27285.

overexpression of miR-892a may provide a selective growth promotion for colorectal cancer cells by direct suppression of PPP2R2A expression.[miR 892a] (Homo sapiens) PubMed

 27286.

Lethe, which was upregulated by activated STAT3, may promoting the replication of HCV through a negative regulatory mechanism of type I IFN response.[Lethe] (Homo sapiens) PubMed

 27287.

Our results provide novel empirical evidence that linc0949 could be a potential biomarker for diagnosis, disease activity and therapeutic response in systemic lupus erythematosus (Homo sapiens) PubMed

 27288.

miR133a may have suppressed cell proliferation, colony formation, migration and invasion via the downregulation of MMP9 in HCC cell lines. (Homo sapiens) PubMed

 27289.

the CD44-miR-199a-3p axis plays an important role in the development of metastasis, recurrence, and drug resistance of osteosarcoma. (Homo sapiens) PubMed

 27290.

found LncRNA AF339813 was positively regulated by NUF2[ LncRNA AF339813 ] (Homo sapiens) PubMed

 27291.

Suggest lncRNA AK124742 and PSMD6 as a new lncRNA-messenger RNA gene pair in human cumulus cells that may be considered as potential biomarkers to aid embryo selection. (Homo sapiens) PubMed

 27292.

suppression of miR-125 expression induced apoptosis, G1/S phase arrest and, to a certain extent, inhibited the invasive ability of lung cancer cells. (Homo sapiens) PubMed

 27293.

miR-124 functions as a tumor suppressor in esophageal cancer through, at least partially, targeting STAT3 signaling pathway. (Homo sapiens) PubMed

 27294.

data identify a novel role of the ArPIKfyve-Sac3 complex in the mechanisms controlling aggregate formation of Sph1 and suggest that Sac3 protein deficiency or overproduction may facilitate aggregation of aggregation-prone proteins [synphilin-1] (Homo sapiens) PubMed

 27295.

Suggest that miR-196aT > C (dbSNP ID rs11614913) may contribute to recurrent miscarriage in North Indian women. (Homo sapiens) PubMed

 27296.

we found that miR-124 may be involved in DNA repair by directly targeting ATMIN and PARP1, suggesting that multiple DNA repair pathways are affected by miR-124 (Homo sapiens) PubMed

 27297.

SCF(beta-TrCP1/2) interacting partners, were identified.[beta TcCP2] (Homo sapiens) PubMed

 27298.

The results reveal the nature of the functional interaction between A*29:02 and ERAP1 and suggest that this enzyme may affect the susceptibility to birdshot chorioretinopathy by altering the A*29:02 peptidome. (Homo sapiens) PubMed

 27299.

lncRNA-CLMAT3 over-expression was significantly associated with colorectal liver metastasis and was an independent predictor of poor survival for patients with colorectal cancer (Homo sapiens) PubMed

 27300.

Smad3 was a direct and functional target of miR-23b in heat-denatured fibroblasts.[miR23] (Homo sapiens) PubMed

 27301.

Cancer procoagulant promotes cancer metastasis at the level of activation rather than degradation.[Cancer procoagulant] (Homo sapiens) PubMed

 27302.

The role of recessive mutations of POLR1C in a leukodystrophy associated with reduced RNA polymerase III (POLR3) is reported.[POLR3] (Homo sapiens) PubMed

 27303.

analysis of a novel state of SAMHD1 (109-626 amino acids, SAMHD1C) that is characterized by a rapid initial hydrolysis rate [SAMHD1] (Homo sapiens) PubMed

 27304.

By blocking miR-181b with an antagomiR, it was possible to increase decorin protein expression in dermal fibroblasts. This suggests miR-181b is involved in the differential expression of decorin in skin and wound healing. [MIRN181b] (Homo sapiens) PubMed

 27305.

Sustained high expression of TEL-AML1 participated in and maintained the occurrence of glucocorticoid resistance.[TEL-AML1] (Homo sapiens) PubMed

 27306.

The folding of the specific DNA recognition subdomain of the sleeping beauty transposase is temperature-dependent and is required for its binding to the transposon DNA. [sleeping beauty transposase] (Homo sapiens) PubMed

 27307.

Cep169 stabilizes microtubules and induces formation of microtubule bundle.Cep169 forms homodimers through its N-terminal domain.[Cep169] (Homo sapiens) PubMed

 27308.

These data support a model by which vsx2, operating through the effector gene opo, acts as a central transcriptional node that coordinates neural retina patterning and optic cup invagination in zebrafish.[opo] (Homo sapiens) PubMed

 27309.

[miR-25-3p] - potential biomarker for the diagnosis of papillary thyroid carcinoma (Homo sapiens) PubMed

 27310.

Our data provide insight into the biological consequences of targeting NAE in CLL and serves as further rationale for studying the clinical activity of MLN4924 in CLL, particularly in combination with alkylating agents. (Homo sapiens) PubMed

 27311.

this study presents the first example of the allorecognition of an HLA-Cw molecule by HLA-A-restricted T-cells, thereby revealing a naturally processed epitope peptide.[HLA-cw7, HLA-A24] (Homo sapiens) PubMed

 27312.

Restoration of miR-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1, GLE1 and PDIA6. (Homo sapiens) PubMed

 27313.

This promoter activity from the CBS5 boundary element generates a long noncoding RNA that we designate as boundary associated long noncoding RNA-1 (blncRNA1). (Homo sapiens) PubMed

 27314.

the association between HLA B35 and HLA B51 and the rate of CD4 decline and/or opportunistic infections, among 294 HIV-positive individuals from Manitoba, Canada, was investigated.[HLA B51] (Homo sapiens) PubMed

 27315.

This study demonstrates that CRL4(DDB2) is a novel ubiquitin ligase of HBO1. (Homo sapiens) PubMed

 27316.

Changes in the membrane potential rapidly alter trafficking of DAT to and from the surface membrane. [DAT] (Homo sapiens) PubMed

 27317.

AP001631.9 expression was frequently increased in gastric cancer tissues[AP001631.9] (Homo sapiens) PubMed

 27318.

the ANG-(1-7)/mas pathway constitutively prevents JNK phosphorylation and apoptosis of alveolar epithelial cells by maintaining activation of the JNK-selective phosphatase mitogen-activated protein kinase phosphatase-2[MAP kinase phosphatase-2] (Homo sapiens) PubMed

 27319.

The AT4R and formation enzymes of AngIII and AngIV are present in the human esophageal epithelium.[Angiotensin IV] (Homo sapiens) PubMed

 27320.

The MALT1-mediated cleavage of HOIL-1 dampens NF- kappa B and lymphocyte activation.(HOIL-1) (Homo sapiens) PubMed

 27321.

Expression of GSE4 increased telomerase activity and reduced DNA damage, oxidative stress and cell senescence in dyskerin-mutated cells.[GSE4] (Homo sapiens) PubMed

 27322.

The HOIL-1 co-operates in a catalytic-independent manner with the E3 ubiquitin ligase HOIL-1L interacting protein (HOIP) as part of the linear ubiquitin chain assembly complex (LUBAC). (HOIL-1) (Homo sapiens) PubMed

 27323.

Serum HIF1A-AS1 in combination with XIST has higher diagnostic efficiency in non-small cell lung cancer than either marker alone. (Homo sapiens) PubMed

 27324.

The peptide P0 is a potential candidate for further development as a synthetic substitute for rhSCF in laboratory and clinical applications. (Homo sapiens) PubMed

 27325.

exposure of DAOY cells to 5-aza-2'-deoxycytidine or their growth as stem cell-like spheres up-regulated endogenous miR-520g with a coincident reduction in tissue factor expression (Homo sapiens) PubMed

 27326.

miR-17 and miR-92 families play important roles in cisplatin resistance and can be used as potential biomarkers for better predicting the clinical response to platinum-based chemotherapy in NSCLC. (Homo sapiens) PubMed

 27327.

HNP-2 association with membranes under these conditions was a 2 stage-process, with both stages exhibiting first order kinetics. (Homo sapiens) PubMed

 27328.

Compressive force might inhibit cell proliferation in osteoblasts by up-regulating miR-494-3p followed by FGFR2 and ROCK1 gene repressions [miR-494-3p] (Homo sapiens) PubMed

 27329.

the diagnostic value of serum cancer antigen (CA)125, CA19-9 and CA15-3 concentrations in endometriosis, was evaluated.[CA 19-9] (Homo sapiens) PubMed

 27330.

MiR-24 functions as a tumor suppressor in nasopharyngeal carcinoma through targeting FSCN1 (Homo sapiens) PubMed

 27331.

miR-1 was suppressed by LMP1 and its tumour-suppressive effects were mediated chiefly by repressing K-ras expression in nasopharyngeal carcinoma. (Homo sapiens) PubMed

 27332.

Upregulation of microRNA1385p inhibits pancreatic cancer cell migration and increases chemotherapy sensitivity (Homo sapiens) PubMed

 27333.

MIRN130 microRNA, human (Homo sapiens) PubMed

 27334.

MicroRNA-7 inhibits the malignant phenotypes of nonsmall cell lung cancer in vitro by targeting Pax6 (Homo sapiens) PubMed

 27335.

Elevated serum preptin and decreased osteocalcin concentrations, together with insulin resistance, are associated with obesity and overweight.[Preptin] (Homo sapiens) PubMed

 27336.

GP73 and AFP-L3 are superior biomarkers to aid the diagnosis of small PHC with negative AFP. The combined detection of biomarkers improved the diagnostic accuracy. (Homo sapiens) PubMed

 27337.

Results underline the relevance of microRNA-101-3p-driven regulation of RRM1 in pancreatic ductal carcinoma gemcitabine resistance. (Homo sapiens) PubMed

 27338.

OsLTPL36 was exclusively expressed in developing seed coat and endosperm aleurone cells. Down-regulated expression of OsLTPL36 led to decreased seed setting rate and 1000-grain weight in transgenic plants.[LTPL36] (Homo sapiens) PubMed

 27339.

a mechanistic role for REST-003 and SRRM3 in regulating cancer cell invasiveness suggests novel therapeutic approaches for limiting breast (and other types of) cancer invasion and metastasis. [REST-003] (Homo sapiens) PubMed

 27340.

W8B2(+) CRSCs are distinct from currently known CRSCs found in human hearts, and as such may be an ideal cell source to repair myocardial damage after infarction. (Homo sapiens) PubMed

 27341.

Co-transduction of Kras(G12D) and AML1/ETO induces acute monoblastic leukemia.[AML1/ETO] (Homo sapiens) PubMed

 27342.

Suggest that lncRNA AB073614 acts as a functional oncogene in ovarian cancer development. (Homo sapiens) PubMed

 27343.

p41 fragment is also shown to reduce the secretion of interleukin-12 (IL-12/p70) during the subsequent maturation of treated dendritic cells.[p41Ii] (Homo sapiens) PubMed

 27344.

the fibrinogen D fragment may have a role in response to thrombolytic therapy in patients with acute deep vein thrombosis [FGD] (Homo sapiens) PubMed

 27345.

Mir23 microrna regulates KDM4A and KDM4a-dependent transient site-specific copy gain. (Homo sapiens) PubMed

 27346.

lncRNA CTB-89H12.4 has a tumor suppressive function and regulates PTEN expression in prostate cancer. (Homo sapiens) PubMed

 27347.

Factor VII-activating protease (FSAP) mediated nucleosome release from late apoptotic cells is greatly impaired in SLE patient sera.[FSAP]. (Homo sapiens) PubMed

 27348.

our data suggest that insertion of the trimeric PEX5-PEX7-PTS2 protein complex into the DTM is probably accompanied by conformational alterations in PEX5 to allow release of the PTS2 protein into the organelle matrix (Homo sapiens) PubMed

 27349.

simultaneous expression of the leukemogenic AF4-MLL and dnTASP1 causes the disappearance of the leukemogenic oncoprotein, because the uncleaved AF4-MLL protein (328 kDa) is subject to proteasomal degradation.[AF4-MLL] (Homo sapiens) PubMed

 27350.

lncRNA-uc002kmd.1 regulates CD44 as a molecular decoy for miR211-3p.[ucoo2kmd.1] (Homo sapiens) PubMed

 27351.

Taspase1 activation as well as the conformation and dynamics of the 56 amino acids loop were investigated.[Taspase 1] (Homo sapiens) PubMed

 27352.

Data reported evidence that the SNPs rs76322625 and rs41281081 in the MET 3'UTR are involved in the occurrence of non-small-cell lung cancer. They are respectively regulated by miR-335 and miR-1026 causing up-regulation of MET in patients. [Mir-1026] (Homo sapiens) PubMed

 27353.

Our data suggest that miR-99b-3p functions as a tumor suppressor in oral squamous cell carcinoma via glycogen synthase kinase-3beta downregulation. (Homo sapiens) PubMed

 27354.

Did not find any positive association between CCDC132 SNPs and the risk of IgA nephropathy after adjustment for age and sex, but did find a significant and strong correlation with relevant clinical pathological parameters. (Homo sapiens) PubMed

 27355.

miR-19b plays a key role in the attenuation of TNF-alpha-induced endothelial cell apoptosis and that this function is closely linked to the Apaf1/caspase-dependent pathway. (Homo sapiens) PubMed

 27356.

Atypical protein kinase C (aPKC) phosphorylates serine-threonine residues of MARK4. (Homo sapiens) PubMed

 27357.

Data suggest peripheral ligand-binding pocket and active site are located on opposite sides of the I-helix in CYP2B4; similar results were obtained for CYP2B6. [CYP2B4, cytochrome P450 2B4] (Homo sapiens) PubMed

 27358.

lncRNA ADINR is developmentally regulated during adipogenesis. ADINR promotes adipogenesis by activating C/EBPalpha transcription. (Homo sapiens) PubMed

 27359.

miR-9, human: new evidence for a role of miR-9-5p in the etiology of schizophrenia. (Homo sapiens) PubMed

 27360.

mirn199 microRNA. miR-199 precursors may be promising therapeutic candidates for the treatment in patients with visceral pain (Homo sapiens) PubMed

 27361.

The multivariate stepwise logistic regression identified the following biomarkers as the best gastric cancer predictors: CEA, CA72-4, pepsinogen I, Helicobacter pylori presence and MMP7 [CA72-4] (Homo sapiens) PubMed

 27362.

C-terminal type I collagen telopeptide serum level is associated with poor prognosis in postmenopausal breast cancer patients.[C-terminal cross-linking telopeptide, collagen type I] (Homo sapiens) PubMed

 27363.

Data suggest that miR-181b-3p functions as a metastasis activator by promoting Snail-induced epithelial-mesenchymal transition in breast cancer cells by directly targeting YWHAG. (Homo sapiens) PubMed

 27364.

high levels of PAI-1 are detected when D allele is present, whereas greater interdialytic gain is associated with the presence of I allele.[Fibrin fragment D] (Homo sapiens) PubMed

 27365.

we conclude that Hec1 is consistently overexpressed in human PCa and Hec1 is closely linked with human PCa progression through the meditator LncRNA BX647187 (Homo sapiens) PubMed

 27366.

The relationship between C-peptide concentrations and D5D enzyme activity estimates remained significant after adjusting for body mass index, waist circumference, and TNF-alpha.[C peptide] (Homo sapiens) PubMed

 27367.

a low level of miR-218 expression was an independent predictor of poor prognosis in pancreatic cancer patient (Homo sapiens) PubMed

 27368.

high level of plasma IL-35 in active SLE patients expressed with low level of IL-35 receptor (gp130) on CD4+ Th cells [IL35] (Homo sapiens) PubMed

 27369.

miR-509-3p sensitized epithelial ovarian cancer cells to apoptosis induced by cisplatin suggests that miR-509-3p is involved in the regulation of apoptosis in ovarian cancer cells and is a promising potential therapeutic target. [MicroRNA-509-3p] (Homo sapiens) PubMed

 27370.

High level of HTI-56 in infected bronchoalveolar lavage fluid samples may reflect the injury of alveolar epithelium caused by M. pneumoniae. (Homo sapiens) PubMed

 27371.

NB4 extracellular vesicles contain PML-RARa transcript, but no detectable protein, which is also absent in endothelial cells upon the vesicle uptake[PML-RARalpha] (Homo sapiens) PubMed

 27372.

(humanin) A significant decrease in humanin was observed in impaired fasting glucose group compared to controls. (Homo sapiens) PubMed

 27373.

Suggest that AK056155 is involved in the development of Loeys-Dietz syndrome through AKT/PI3K signaling pathway. (Homo sapiens) PubMed

 27374.

These results suggested that fucosterol executed its protective effects against CoCl2 induced cytotoxicity and inflammation by the inhibition of hypoxia inducible factor through PI3K/Akt pathway.[PI3K] (Homo sapiens) PubMed

 27375.

the results of the present study suggest that miR-181b functions as an oncogene during breast cancer development[Mir-181b] (Homo sapiens) PubMed

 27376.

The substrate Angiotensin II, the enzymes aminopeptidases-A, B, M as well as IRAP were detected in the jejunal mucosa.[Angiotensin IV] (Homo sapiens) PubMed

 27377.

we performed a meta-analysis of our data with the previous reports, identifying two further loci harbouring the ZNF335 and NIFA genes which now exceed genome-wide significance, taking the total number of CD susceptibility loci to 42. (Homo sapiens) PubMed

 27378.

Hsa-miR-1 suppresses breast cancer development by down-regulating K-ras and long non-coding RNA MALAT1 (Homo sapiens) PubMed

 27379.

REVIEW: Data strongly suggests that the optimal levels of MBL activity depend on the age and on the environmental context of each subject [mannose binding lectin] (Homo sapiens) PubMed

 27380.

MiR-103 regulates hepatocellular carcinoma growth by targeting AKAP12 [miR-103] (Homo sapiens) PubMed

 27381.

conclusion supplementation with selenium and coenzyme Q10 during four years resulted in less concentration of both copeptin and MR-proADM (Homo sapiens) PubMed

 27382.

miR-548d-3p/TP53BP2 pathway is critically involved in the proliferation and apoptosis of breast cancer cells and may be new therapeutic target of breast cancer cells. (Homo sapiens) PubMed

 27383.

miRNA-197 and miRNA-184 are overexpressed in EGFR-mutant patients with brain metastasis (Homo sapiens) PubMed

 27384.

Cardiac expression levels of miR-199b are increased in Left ventricular hypertrophy and Heart failure. (Homo sapiens) PubMed

 27385.

conditional logistic regression analysis revealed the aberrant expression of CTD-2541M15, UCA1 and MEG3 closely linked with Gastric cancer (Homo sapiens) PubMed

 27386.

Data suggest the pharmacological induction of non-coding RNA NDM29 (neuroblastoma differentiation marker 29) might represent a strategy to increase cytotoxic drug responses: [NDM29 ncRNA] (Homo sapiens) PubMed

 27387.

These results clarify that PGRMC1 and the S2R are distinct binding sites expressed by different genes. (Homo sapiens) PubMed

 27388.

Ox-LDL levels are higher among Tibetan elderly highlanders compared with those among Han elderly. [oxl-LDL] (Homo sapiens) PubMed

 27389.

The AMH and AMHRII gene polymorphisms were not found a significant difference in non-IR-PCOS and normal groups. To IR-PCOS women, genotypes of AMH were closely related to the serum levels of LH (P = 0.000), testosterone (P = 0.000) and HOMA-IR (P = 0.038), while in the non-IR-PCOS and normal groups, no relationship was found (Homo sapiens) PubMed

 27390.

miR-548-3p inhibited the proliferation of breast cancer cells by regulating the expression of ECHS1, indicating its potential as a therapeutic target for breast cancer. (Homo sapiens) PubMed

 27391.

The present study revealed that salivary extracellular HSP70 significantly increased at 4 h after the 59 min of intense exercise in sedentary male subjects and correlated with resting salivary secretory immunoglobulin A (SIgA) levels at rest. [secretory immunoglobulin A] (Homo sapiens) PubMed

 27392.

CEA, NSE, CA125 and pro-GRP could serve as biomarkers for SCLC, and CEA and CYFRA21-1 could serve as biomarkers for NSCLC. Pro-GRP, CA125 and CEA were related to the clinical stages of lung cancer (Homo sapiens) PubMed

 27393.

Serum levels of preptin and amylin were significantly lower in patients with psoriasis and Behcet's disease.[Preptin] (Homo sapiens) PubMed

 27394.

Our findings highlight the critical ECM-tumor cell interactions regulated by miR-200/Zeb1-dependent EMT that activate intracellular signaling pathways responsible for tumor cell invasion and metastasis. (Homo sapiens) PubMed

 27395.

allelic competition in the the ABO 547G>A carrying individuals is associated with reduced activity of glycosyltransferase B. (Homo sapiens) PubMed

 27396.

This analysis demonstrated that, in patients with metastatic pancreatic cancer , any CA19-9 decrease at week 8 can be an early marker for chemotherapy efficacy, including in those patients with stable disease . CA19-9 decrease identified more patients with survival benefit than radiologic response by week 8. (Homo sapiens) PubMed

 27397.

The immunostaining of FNA breast specimens for p63 and CK 34beta-E12 may help in difficult diagnoses. (Homo sapiens) PubMed

 27398.

Our study demonstrates that RPS23RG1 may reduce the occurrence of key elements of AD pathology and enhance synaptic functions to counteract oAbeta-induced synaptic and cognitive deficits in AD (Homo sapiens) PubMed

 27399.

Serum amino-terminal procollagen type III (PIIIP) levels were higher among the single ventricle groups than among control patients. Severity of volume load and cyanosis were independent determinants of increased PIIIP levels in patients before Fontan surgery, and persistently increased PIIIP after Fontan surgery was associated with ventricular diastolic stiffening. [procollagen type III N-terminal amino peptide] (Homo sapiens) PubMed

 27400.

Results indicate a role for Yes associated protein (YAP), which is inhibited by the Hippo pathway, in the cytokinesis machinery during mitosis through interaction with the polarity protein PATJ: [Hippo] (Homo sapiens) PubMed

 27401.

Our study firstly investigates the potential function of LOC101926975 in Hirschsprung disease(HSCR) and infers that LOC101926975 can distinguish HSCR from the normal ones. (Homo sapiens) PubMed

 27402.

provided evidences that miR-10 regulates human endothelial cells behaviour through targeting Mib1 as well [MicroRNA-10a/10b] (Homo sapiens) PubMed

 27403.

miR-194 is predicted to target key molecules and pathways involved in RCC progression. miR-194 represents a prognostic biomarker in ccRCC. (Homo sapiens) PubMed

 27404.

Here is proposed a model in which specific amino acids in assorted compartments activate different mTORC1 complexes, which may have distinct drug sensitivities and functions. Discussed are the implications of this for mTORC1 function in health and disease. [mTORC1] [review] (Homo sapiens) PubMed

 27405.

a P-TEFb activation mechanism reveal altered enhancer RNA expression that is related to abnormal AR function and may potentially be a therapeutic target in Castration-Resistant Prostate Cancer.[P-TEFb] (Homo sapiens) PubMed

 27406.

predicted binding of one CD74 trimer to a single RTL1000 antagonist utilized the same two 5 residue determinants[RTL1000] (Homo sapiens) PubMed

 27407.

miR-130b expression was downregulated, while RUNX3 mRNA was upregulated, in EOC tissues compared to normal ovarian tissues (both P=0.001). Importantly, the expression level of miR-130b in EOC tissues was negatively correlated with that of RUNX3 mRNA significantly. [miR-130b] (Homo sapiens) PubMed

 27408.

the results of this study suggest that the miR-24/SP1 pathway contributed to the reduction in radioresistance in human NPC and that it may thus represent a therapeutic target. (Homo sapiens) PubMed

 27409.

hypoxia induced miR-124 and miR-144 downregulation may contribute to a prosurvival mechanism of prostate cancer cells to hypoxia and irradiation at least through attenuated suppressing of PIM1. (Homo sapiens) PubMed

 27410.

downregulation of miR-1207-5p and miR-4695-3p expression may lead to increased TRIM21 levels in the minor salivary glands, which contributes to the development of Sjogren's syndrome [mirn4695] (Homo sapiens) PubMed

 27411.

Findings indicate the importance of a microRNAs miR-9/137-CUL4A-Hippo signaling axis in gastric cancer (GC), and suggest new therapeutic targets for future treatment of GC: [Hippo] (Homo sapiens) PubMed

 27412.

miR-24-3p plays an important role in the initiation and progression of hepatocellular carcinoma by targeting metallothionein 1M.[miR24-3] (Homo sapiens) PubMed

 27413.

The expression of miR-30a-5p and miR-181-5p is regulated by its target, SRSF7, forming regulatory feedback circuit.[miR-181-5p ] (Homo sapiens) PubMed

 27414.

miR-181b directly inhibits the expression level of hexokinase 2 (HK2), a key enzyme that catalyzes the first step of glycolysis, through targeting its 3'-untranslated region. (Homo sapiens) PubMed

 27415.

Overexpressed miR-1280 levels in thyroid carcinoma cells may promote cell proliferation and invasion by inhibiting ER-alpha. [miR-1280 ] (Homo sapiens) PubMed

 27416.

This reason was demonstrated that signal transducer and activator of transcription 1 (STAT1) was a transcriptional repressor of osteoblast gene (Runx 2) expression during osteoblast differentiation, miR-129-5p reduced STAT1 levels, leading to the accumulation of correctly spliced Runx 2 mRNA and a dramatic increase in Runx 2 protein. [miR-129-5p ] (Homo sapiens) PubMed

 27417.

the role of miR-30 in the development of Gastric cancer (Homo sapiens) PubMed

 27418.

Elevated plasma D-dimer level could be served as an independent determinant of poor prognosis in patients with small cell lung cancer.[Fibrin D dimer] (Homo sapiens) PubMed

 27419.

Breastfeeding is associated with increased infants' fecal secretory IgA levels and may have potential protective effects to the infants during the first 4 months of life, regardless of whether their lactating mothers have allergies [secretory immunoglobulin A]. (Homo sapiens) PubMed

 27420.

our results demonstrate that upregulation of ITGA9 in response to the decrease in miR-125b in metastatic melanoma is responsible for melanoma tumor cell migration and invasion. (Homo sapiens) PubMed

 27421.

Through the application of a pathogenicity scoring system, this variant was determined to be a "neutral polymorphism," with a score of only 4 points based on current data. Thus, the contribution of the A12307G variant of the tRNA(Leu(CUN)) to pancreatic cancer needs to be addressed in further experimental studies. (Homo sapiens) PubMed

 27422.

An association between the rs188912830 gene variant of miR3202 that targets the MeCP2 protein and lung cancer (LC) was indicated in both subtypes. The rs318039 gene variant of miR1274 that targets DNMT3b was found to be associated with LC subtypes. [MIR1274] (Homo sapiens) PubMed

 27423.

our findings suggest that MVIH may have an important role in breast cancer and may serve as a new biomarker and a potential therapeutic target. (Homo sapiens) PubMed

 27424.

The lncRNA HOTAIR indicated a poor prognosis for patients with esophageal squamous cell carcinoma (ESCC), and it may also have predictive potential for ESCC metastasis. (Homo sapiens) PubMed

 27425.

increased Linc00152, CFLAR-AS1 and POU3F3 might be potential biomarkers for predicting the early progress of esophageal squamous cell carcinoma.[CFLAR-AS1, POU3F3 lncRNA] (Homo sapiens) PubMed

 27426.

Both CD44 and CD44v6 may be useful diagnostic or prognostic biomarkers for gastric cancer.[CD44v6] (Homo sapiens) PubMed

 27427.

Long non-coding RNA FTH1P3 facilitates oral squamous cell carcinoma progression by regulating miR-224-5p and FZD5.[Long non-coding RNA FTH1P3] (Homo sapiens) PubMed

 27428.

Long non-coding RNA AK027294 was found to be highly expressed in colorectal cancer tissues compared with colorectal adenoma tissues. Its down-regulation significantly inhibited colorectal cancer cells proliferation and migration, but promoted cell apoptosis. The potential mechanism of AK027294 might be associated with the regulation of caspase-3, caspase-8, Bcl-2, MMP12, MMP9, and TWIST. (Long non-coding RNA AK027294). (Homo sapiens) PubMed

 27429.

SCCAg, CYFRA 21.1, IL-6, VEGF and sTNF receptors have roles in squamous cell cervical cancer [SCCAg and CYFRA 21.1] (Homo sapiens) PubMed

 27430.

miR-181a suppresses apoptotic signaling factor RASSF1, which elicits sorafenib resistance of HCC cells. (Homo sapiens) PubMed

 27431.

CHD5 is the direct target of miR-24-3p which is required for the regulatory role of miR-24-3p in chemoresistance. miR-24-3p may represent a new therapeutic target for the improvement of clinical outcome in HNSCC (Homo sapiens) PubMed

 27432.

p44/42 MAPK phosphorylation, the signaling pathway which is often regulated by beta-arrestins is not influenced by KLHL12, but seems to be exclusively mediated by Galphai protein upon dopamine D4 receptor stimulation[CTNNB2]. (Homo sapiens) PubMed

 27433.

The findings suggest a probable tumor suppressor role for miR-1267 and miR-2276 in breast tumor initiation and progression, but a probable promoting role for them in invasion and metastasis. [MIRN2276] (Homo sapiens) PubMed

 27434.

Serum CA-19-9 elevated expression in colorectal cancer recurrence after surgery (Homo sapiens) PubMed

 27435.

mirn199 microRNA, human. Our findings added newer insights into the multifaceted role played by miR-199a-5p/C-C chemokine receptor type 7 in bladder cancer, prompting for the first time this miRNA/chemokine axis that regulates cell metastasis. The results strongly supported miR-199a-5p as a potential therapeutic agent and diagnostic marker of bladder cancer (Homo sapiens) PubMed

 27436.

miR-450 targets IRF2 and supresses lung cancer cell proliferation and invasion.[mir450] (Homo sapiens) PubMed

 27437.

miR-513a-5p, miR-22-3p and miR-625-5p may have an impact on the regulation of the immune response and inflammatory cytokine pathways through the regulation of their target gene(s), CBL, PPARGC1B and ESR1, which may then lead to a dust mite-induced asthma attack.[mir513a] (Homo sapiens) PubMed

 27438.

Our study uncovers a novel mechanism that miR-19a-3p/19b-3p inhibits autophagy-mediated fibrogenesis by targeting TGF-beta R II. (Homo sapiens) PubMed

 27439.

the novel lncRNA NONHSAT037832 is downregulated in PTC, and the expression level of NONHSAT037832 was correlated with lymph node metastasis and tumor size. NONHSAT037832 may be a potential diagnostic biomarker for PTC. (Homo sapiens) PubMed

 27440.

MAOs, particular monoamine oxidase B, contribute to oxidative stress in human diseased hearts with/without diabetes mellitus. (Homo sapiens) PubMed

 27441.

findings indicated that lincRNA-p21 inhibited development of human prostate cancer partly by regulating p53 downstream gene expression and partly by apoptotic activation[lincRNA-p21] (Homo sapiens) PubMed

 27442.

lncRNA n375709 was identified to be involved in the regulation of nasopharyngeal carcinoma paclitaxel resistance. (Homo sapiens) PubMed

 27443.

findings show that MALAT1 plays an important role in regulating the expression of stemness markers and proliferation of SHG139S[lncRNA-MALAT1] (Homo sapiens) PubMed

 27444.

In multivariable analysis preoperative high CA19-9 (>==230) was a prognostic factor for poor survival in pancreatic ductal carcinoma. Kaplan-Meier survival analysis demonstrated the overall 2-year survival rate in patients with high CA19-9 was 37.5% compared with 89.9% in patients with low CA19-9. [CA19-9] (Homo sapiens) PubMed

 27445.

These results indicate that oxidative stress impairs the ability of S100 proteins to bind and activate PP5, which in turn modulates the ASK1-mediated signaling cascades involved in apoptosis.[Protein phosphatase 5] (Homo sapiens) PubMed

 27446.

IL-35 level is associated with in promoting tumor progression.[review] (Homo sapiens) PubMed

 27447.

miR129 is downregulated in the cancerous tissues of prostate cancer patients, which was associated with poor BCRfree survival. Thus, it may be considered as a novel independent prognostic biomarker for prostate cancer. (Homo sapiens) PubMed

 27448.

the data demonstrate that miR125a5p functions as a tumor suppressor gene and serves an important role in inhibiting osteosarcoma cell migration, invasion and EMT by targeting MMP11. (Homo sapiens) PubMed

 27449.

Cox-proportional regression analysis revealed prognostic importance of combination of circulating miR192 and CA19-9 (HR = 1.005, P = 0.0001) in periampullary carcinoma. In conclusion, combination of circulating miRNA192 with serum CA19-9 is a better prognostic biomarker than CA19-9 alone. (Homo sapiens) PubMed

 27450.

TP53 was identified as a target of miR125b, and the minor allele of the rs78378222 polymorphism promoted the miR-125b/TP53 mRNA interaction. (Homo sapiens) PubMed

 27451.

the E50K OPTN mutation markedly reduced the levels of miR-9, which led to alterations in REST and reduced expression levels of BDNF in RGC-5 cells. (Homo sapiens) PubMed

 27452.

lncRNAs are differentially expressed in the LAPV and LAA in patients with AF. AK055347 may contribute to the pathogenesis of AF by dysregulating mitochondrial energy production via regulation of Cyp450, ATP synthase and MSS51. (Homo sapiens) PubMed

 27453.

miR-196a was downregulated in RCC tissues compared with that in normal adjacent tissues. Transfection with miR-196a mimics inhibited the proliferation and migration of the 786-O and ACHN RCC cell lines, while inducing apoptosis. (Homo sapiens) PubMed

 27454.

hsamiR3715p is downregulated in LN, and overexpression of hsamiR3715p may inhibit mesangial cell proliferation and promote apoptosis by directly targeting HIF1alpha. (Homo sapiens) PubMed

 27455.

Kaplan-Meier survival analysis indicated that miR-125b-5p levels were associated with 6 month cardiovascular events in patients with AMI, but not miR30d5p. miR-125b-5p and miR-30d-5p presented a diagnostic value for early diagnosis of AMI, and miR30d5p may have a higher diagnostic value than cTnI (Homo sapiens) PubMed

 27456.

it was demonstrated that miR218 modulated a novel molecular target and the present study provided novel insights into potential mechanisms of RCC oncogenesis. (Homo sapiens) PubMed

 27457.

miR-101 is downregulated in bladder cancer cells and has an inhibitory role in the regulation of bladder cancer cell proliferation and invasion via directly targeting c-FOS. (Homo sapiens) PubMed

 27458.

The findings suggested that colorectal cancer-associated lncRNA (CCAL) plays critical roles in osteosarcoma progression (CCAL). (Homo sapiens) PubMed

 27459.

The preferential expression of DQ2.5 alleles provides a new functional explanation of why these genes are so frequently associated with celiac disease and with other autoimmune disorders. (Homo sapiens) PubMed

 27460.

FFA, TNF-alpha, IL6 and leptin significantly induced miR199a3p expression in mature human adipocytes, while resistin had the opposite effect. miR199a3p may represent a factor in the modulation of obesityassociated IR and inflammatory responses. (Homo sapiens) PubMed

 27461.

miR-15b levels increased in human degenerative nucleus pulposus (NP) tissues. miR-15b silencing inhibited IL-1beta-induced ECM degradation in human NP cells via increase in SMAD3 expression. [miRNA15b] (Homo sapiens) PubMed

 27462.

Biliary CA19-9 levels were grossly (and unexpectedly) raised in choledochal malformation and appear to arise from biliary rather than pancreatic epithelium. [CA19-9] (Homo sapiens) PubMed

 27463.

High preoperative serum CA19-9 level is predictive of poor prognosis for patients with colorectal liver oligometastases undergoing hepatic resection. [ca 19-9] (Homo sapiens) PubMed

 27464.

Study shows that AC012065.7 lncRNA is hypomethylated in chronic lymphocytic leukemia (CLL) and identifies CRNDE with a potential role in CLL disease pathogenesis and/or prognosis. [AC012065.7] (Homo sapiens) PubMed

 27465.

study is the first to demonstrate crosstalk between MAPK activation and reduction in miR-19a, -19b, and -26b expression leading to lung fibroblast differentiation[miR-19a, -19b, and -26b] (Homo sapiens) PubMed

 27466.

simultaneous increased expression level of MMP-2 and decreased expression level of the studied miRNAs were observed in 31 NSCLC samples (86.1 %) for miR- 29b, 28 NSCLC samples (73.7 %) for miR-519d[mir519] (Homo sapiens) PubMed

 27467.

miR-105 functions as a potential tumor suppressor by regulating the SOX9/TCF4 axis in glioma (Homo sapiens) PubMed

 27468.

[Zfp335] Zfp335 binds DNA and drives transcription via recognition of two distinct consensus motifs by separate ZF clusters and identify the specific motif interaction disrupted by R1092W (Homo sapiens) PubMed

 27469.

High expression of lncRNA-ATB indicated a poor prognosis and led to the cell proliferation and metastasis in non-small cell lung cancer[ATB] (Homo sapiens) PubMed

 27470.

FDX1 and FDX2 both bind NFS1 and donate electrons for iron-sulfur cluster biosynthesis. [FDX2] (Homo sapiens) PubMed

 27471.

In women with contractions and cervical length </= 20 mm, fetal fibronectin is an effective marker of preterm delivery. [FFN protein, fetal fibronectin] (Homo sapiens) PubMed

 27472.

GlcNAc-1-PT lacking spacer-1 exhibits enhanced phosphorylation of several non-lysosomal glycoprotein.[GlcNAc-1-PT] (Homo sapiens) PubMed

 27473.

Serum hepcidin was significantly higher in inflammatory bowel disease patients (IBD) with active disease compared with both coeliac and healthy patients and increased serum hepcidin is responsible for iron malabsorption in IBD patients. [hepcidin 25 isoform] (Homo sapiens) PubMed

 27474.

Cervicovaginal fluid fetal fibronectin concentrations in asymptomatic high-risk women are not affected by the presence of a low-lying placenta. [FFN protein, fetal fibronectin] (Homo sapiens) PubMed

 27475.

Hsa_circ_0000096 was found to be significantly downregulated in gastric cancer tissues and gastric cancer cell lines. hsa_circ_0000096 affected gastric cancer cell growth and migration by interfering with the expression of cell cycle-associated and migration-associated proteins. (Homo sapiens) PubMed

 27476.

miR133a is significantly increased in plasma from hyperlipidemic compared with normolipidemic patients. Expression of miR133a in IL-19 stimulated VSMC represents a previously unrecognized link between vascular lipid metabolism and inflammation, and may represent a therapeutic opportunity to combat vascular inflammatory diseases. (Homo sapiens) PubMed

 27477.

Data suggest that up-regulation of expression of two novel long noncoding RNAs (lncRNAs), XLOC_051122 and XLOC_006074, is associated with poor prognosis in patients with papillary thyroid carcinoma; patients with lymph node metastasis exhibited significantly higher levels of expression of these two lncRNAs in tumor tissue. [XLOC_051122 (chr9:109984408-110018228) and XLOC_006074 (chr10:54643921-54681370)] (Homo sapiens) PubMed

 27478.

Sensitivity to glucocorticoids did not appear to be mediated by changes in the expression of the beta variant of the glucocorticoid receptor or the 11-beta hydroxysteroid dehydrogenase 2 isozyme. [Glucocorticoid Receptor, beta isoform] (Homo sapiens) PubMed

 27479.

LncRNA-ATB was up-regulated in fibrotic liver tissues and activated LX-2 cells. Knockdown of lncRNA-ATB could down-regulate beta-catenin expression by up-regulating the endogenous miR-200a. (Homo sapiens) PubMed

 27480.

miR-199a-5p is down-regulated in lung tumor samples. miR-199a-5p interacts with 3'-UTR of GRP78. (Homo sapiens) PubMed

 27481.

These studies reveal a co-regulatory mechanism of Brd4 and elongation complex in modulating the transcriptional pause release by recruiting multiple P-TEFbs via a Mediator- and Paf1c-coordinated recruitment network.[P-TEFb] (Homo sapiens) PubMed

 27482.

The p48 isoform of Ebp-1, which localizes in the cytoplasm and nuclei, promoted HCV replication, whereas the shorter p42 isoform of Ebp-1, which resides exclusively in the cytoplasm, strongly inhibited HCV replication [Ebp-1] (Homo sapiens) PubMed

 27483.

H1.X moves more rapidly than other linker histones in vivo Domain swapping between H1.0 and H1.X suggests that the globular domain (GD) and C-terminal domain (CTD) of H1.X independently contribute to the dynamic behavior of H1.X.[H1.X] (Homo sapiens) PubMed

 27484.

Results showed that the TMSB4 pseudogene, lncRNA-MSR, was upregulated in the damaged cartilage and was activated in chondrocytes in response to mechanical stress. Furthermore, lncRNA-MSR regulated the expression of TMSB4 by competing with miRNA-152 in chondrocytes.[lncRNA-MSR] (Homo sapiens) PubMed

 27485.

Our findings strongly suggested that serum miR-1826 could serve as an effective and non-invasive biomarker for diagnosis and prognosis of colorectal cancer. Circulating miR-1826 may be an important target in colorectal cancer therapy. (Homo sapiens) PubMed

 27486.

There are higher rates of lung transplant patients treated for rejection within the first year who are either negative for the HLA-DR15 allele but received a donor-positive lung or positive for the HLA-DR13 allele but received a donor-negative lung for that allele. However, these differences do not appear to affect long-term outcomes. [HLA-DR15 and HLA-DR13] (Homo sapiens) PubMed

 27487.

Further study suggested that lncRNA-PE downregulated miR-200a/b by repressing the primary transcript expression, enhanced ZEB1 expression, and promoted epithelial-mesenchymal transition of hepatocellular carcinoma cells. All these data imply that lncRNA-PE might play an important role in hepatocellular carcinoma development via the miR-200a/b-ZEB1 pathway. (Homo sapiens) PubMed

 27488.

Overexpression of miR-105 inhibited cell proliferation, tumorigenesis, migration, invasion, and drug sensitivity, whereas overexpression of suppressor of Zeste 12 homolog antagonized the tumor-suppressive functions of miR-105. (Homo sapiens) PubMed

 27489.

histone binding to ASF1B is required for the induction of beta-cell proliferation.[Histone H3.3] (Homo sapiens) PubMed

 27490.

This study found that the expression level of Long Noncoding RNA C21orF96 was over-expressed in positive lymph node tissues and gastric cancer tissues. The expression levels of C21orF96 were associated with gross appearance, lymphatic metastasis and distal metastasis. [Long Noncoding RNA C21orF96 ] (Homo sapiens) PubMed

 27491.

YAP/TAZ act as natural inhibitors of TBK1 and are vital for antiviral physiology.[Hippo] (Homo sapiens) PubMed

 27492.

QKI-5 stabilized RASA1 mRNA via directly binding to the QKI response element region of RASA1, which in turn prevented the activation of the Ras-MAPK signaling pathway, suppressed cellular proliferation and induced cell cycle arrest.[QKI-5] (Homo sapiens) PubMed

 27493.

High miR-1826 expression was significantly associated with some clinicopathologic features such as regional lymph node metastasis (p=0.018), advanced TNM clinical stage (p=0.004), which led to a poor overall survival rate in Colorectal Cancer patients (p=0.032). [miR-1826] (Homo sapiens) PubMed

 27494.

MiR-27a-3p is an endogenous promoter of metastatic invasion in nasopharyngeal carcinoma.Mapk10 expression was regulated by miR27a-3p in nasopharyngeal carcinoma.[MiR-27a-3p] (Homo sapiens) PubMed

 27495.

MiR-329-3p is down-regulated in cervical cancer.MicroRNA-329-3p targets MAPK1 to suppress cell proliferation, migration and invasion in cervical cancer. [mir-329-3p] (Homo sapiens) PubMed

 27496.

hsa_circ_0001895 expression levels were significantly correlated with cell differentiation, Borrmann type, and tissue carcino-embryonic antigen expression. Our results suggested that hsa_circ_0001895 may play crucial roles during gastric cancerogenesis and is a potential biomarker for clinical prognosis prediction (Homo sapiens) PubMed

 27497.

Protein induced by vitamin K absence or antagonist-II showed higher area under the curve than alpha-fetoprotein for diagnosis of hepatitis B virus-related hepatocellular carcinoma patients (0.901 vs 0.788).We conclude that Combining alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II may improve the diagnostic value for early detection of hepatocellular carcinoma. (Homo sapiens) PubMed

 27498.

SnoN interacts with multiple components of the Hippo pathway to inhibit the binding of Lats2 to TAZ and the subsequent phosphorylation of TAZ, leading to TAZ stabilization.[Hippo] (Homo sapiens) PubMed

 27499.

STAT3 and miR-181b control each other's expression in a positive feedback loop that regulates SFCs via CYLD pathway (miR-181b). (Homo sapiens) PubMed

 27500.

HIT000218960 might acts as a tumor promoter through regulating the expression of HMGA2.[HIT000218960] (Homo sapiens) PubMed

 27501.

LncRNA-AK001085 was down-regulated in ankylosing spondylitis patients and it could be an independent diagnostic indicator.[lncRNA AK001085] (Homo sapiens) PubMed

 27502.

our findings suggest that the HIF-1alpha-HDAC1 complex transcriptionally inhibits miR-548an expression during hypoxia, resulting in the upregulation of vimentin that facilitates the pancreatic tumorigenesis. (Homo sapiens) PubMed

 27503.

The miR-130b-3p down-regulates PGC-1alpha expression in placental trophoblasts, and inhibition of miR-130b-3p appears to improve mitochondrial biogenesis signaling and protect placental trophoblast cells from oxidative stress. (Homo sapiens) PubMed

 27504.

Children with Mycoplasma pneumoniae pneumonia had significantly higher levels of sB7-H3 and IL-36 compared to control subjects. [IL-36] (Homo sapiens) PubMed

 27505.

The present meta analysis strongly supported the prognostic role of VEGF-C expression for disease free survival and overall survival in Breast Cancer patients, especially for patients in non-Asian countries. Furthermore, stratification by VEGF-C expression may help to optimize the treatments and the integrated managements for BC patients. [VEGF-C] (Homo sapiens) PubMed

 27506.

Up to the present day, carbohydrate antigen 19-9 is the only diagnostic marker approved by the U.S. Food and Drug Administration but its diagnostic potential is limited due to its restricted sensitivity and specificity, supporting the urgent need for novel biomarkers. (Homo sapiens) PubMed

 27507.

miR-125b and miR-532-3p are potential non-invasive biomarkers, detectable in the peripheral blood of CLL patients before treatment, which predict rituximab-mediated lymphodepletion efficacy. (Homo sapiens) PubMed

 27508.

Results of the luciferase reporter gene assay demonstrated that miR-1-3p targeted CCL2. MiR-1-3p suppresses the proliferation and invasion of urinary bladder cancer cells by targeting CCL2. (Homo sapiens) PubMed

 27509.

MIRN130 microRNA, human. MicroRNA-130b is a novel negative regulator of the type I IFN pathway in renal cells. Overexpression of miR-130b in vivo ameliorates IFNalpha-accelerated lupus nephritis, providing potential novel strategies for therapeutic intervention in lupus nephritis (Homo sapiens) PubMed

 27510.

PINK1 disease mutants failed to recruit synphilin-1 and did not activate mitophagy, indicating that PINK1-synphilin-1-SIAH-1 represents a new parkin-independent mitophagy pathway. Drugs that activate this pathway will provide a novel strategy to promote the clearance of damaged mitochondria in Parkinson's disease. (Homo sapiens) PubMed

 27511.

Our results suggested that microRNA-129-5p could directly specifically suppress SPOCK1, which might be one of the potential mechanisms in inhibiting cell processes including viability, proliferation, cell mitosis, migration, and invasiveness of gastric cancer cells. (Homo sapiens) PubMed

 27512.

Our data imply that hsa_circ_0006633 may play an important role in gastric carcinogenesis and is also a potential biomarker for screening gastric cancer. (Homo sapiens) PubMed

 27513.

we identified PTEN as a direct and functional target of miR-193a-3p, at least partly responsible for promoting tumor effect of miR-193a-3p in renal cell carcinoma. Taken together, the findings indicated for the first time that miR-193a-3p functions as a tumor-promoting microRNA by directly targeting PTEN in renal cell carcinoma. (Homo sapiens) PubMed

 27514.

In this study, snaR was identified as upregulated and to play a role in cancer progression of HER2-positive breast cancer cells. These results suggest snaR as a potential biomarker for HER2-positive breast cancer (Homo sapiens) PubMed

 27515.

The authors report a novel PRC2-Ezh1 function that utilizes Ezh1beta as an adaptive stress sensor in the cytoplasm, thus allowing postmitotic cells to maintain tissue integrity in response to environmental changes.[PRC2] (Homo sapiens) PubMed

 27516.

The highly expressed XLOC_008466 acts as an oncogenic lncRNA that promotes the tumorigenesis and progression of non-small cell lung cancer through the miR-874-MMP2/XIAP axis, indicating that XLOC_008466 could be a useful marker and potential therapeutic target for non-small cell lung can cer . (Homo sapiens) PubMed

 27517.

observe that while miR-23 is capable of down-regulating the shortened KGA 3'UTR, it has only minor impact on the full-length KGA 3'UTR, demonstrating that additional potent negative regulation of GLS expression exists beyond this single microRNA targeting site [microRNA 23] (Homo sapiens) PubMed

 27518.

the upregulation of hsamiR101 in ccRCC was induced by hypoxia. Its expression deceased the protein expression of TIGAR and promoted glycolysis. This regulatory pathway may represent a novel mechanism of carcinogenesis and requires further investigation. (Homo sapiens) PubMed

 27519.

Both IL-6 and D-dimer are independently associated with serious non-AIDS conditions or death among HIV-positive adults with suppressed virus.[D-dimer] (Homo sapiens) PubMed

 27520.

report a pediatric case of acute T-lymphoblastic leukemia (T-ALL) with NOTCH1(wt) , FBXW7(wt) , STIL/TAL1, and PTEN (exons 2, 3, 4, 5) monoallelic deletions, biallelic CDKN2A/B deletion, and a minor t(8;14)(q24;q11)-positive subclone[cdkn2b] (Homo sapiens) PubMed

 27521.

we characterized the clinicopathologic relevance of a novel gallbladder cancer-associated suppressor of pyruvate carboxylase lncRNA (lncRNA GCASPC) in gallbladder cancer progression (Homo sapiens) PubMed

 27522.

PDE/cGMP/PKG signaling targets Hippo/TAZ pathway to maintain stemness of prostate cancer stem cells. (Homo sapiens) PubMed

 27523.

miR-9 was confirmed an oncomiR when found to be overexpressed in tumour tissue as compared to adjacent benign glandular epithelium through laser-capture microdissection of radical prostatectomy biopsies. Inhibition of miR-9 resulted in reduced migratory and invasive potential of the M12 cell line, and reduced tumour growth and metastases in male athymic nude mice. (Homo sapiens) PubMed

 27524.

miR-30d and/or its target gene MYPT1 may serve as novel prognostic markers of PCa. miR-30d promotes tumor angiogenesis of PCa through MYPT1/c-JUN/VEGFA pathway. (Homo sapiens) PubMed

 27525.

the lncRNA CRNDE could regulate the progression and chemoresistance of CRC via modulating the expression levels of miR-181a-5p and the activity of Wnt/beta-catenin signaling. (Homo sapiens) PubMed

 27526.

SOX2 regulates the proliferation, migration and invasiveness of breast cancer cells through miR-181a-5p and miR-30e-5p which modulate TUSC3 protein levels (Homo sapiens) PubMed

 27527.

primarily due to high sequence similarity in the motifs utilized by polyadenylation machinery and the PUM complex[pumilio] (Homo sapiens) PubMed

 27528.

Long non-coding RNA Unigene56159 binds to miR-140-5p and effectively act as a competing endogenous RNA (ceRNA) for miR-140-5p to de-repress the expression of the target gene Slug in hepatocellular carcinoma cells. (Homo sapiens) PubMed

 27529.

we conducted a retrospective study to evaluate the correlation between clinical-pathological parameters, serum levels of neuron-specific enolase and CYFRA21-1, and bone metastases in lung cancer patients.Multivariate logistic regression analysis showed that patients' age concentrations of neuron-specific enolase and histopathological types were the independent risk factors for bone metastases in patients with lung cancer (Homo sapiens) PubMed

 27530.

miR-24-3p suppresses tumorigenesis by down-regulation of PRKCH expression in lacrimal adenoid cystic carcinoma cells. (Homo sapiens) PubMed

 27531.

the miR-499GG genotype is associated with an increased risk of OPLL in the segmental OPLL subgroup and that the miR-146a/-149/-196a2/-499 allele combinations may be a genetic risk factor for cervical OPLL in the Korean populations. (Homo sapiens) PubMed

 27532.

the recruitment of CREBBP and SRSF1 to nuclear stress bodies is Sat3-dependent, and that loss of Sat3 transcripts relieves the heat-shock-induced transcriptional repression of a few target genes.[Sat3] (Homo sapiens) PubMed

 27533.

MIRN-181 microRNA, human. Results establish the counteraction between NDRG2 and LIF/miR-181c as a key mechanism that regulates cholangiocarcinogenesis and metastasis. Our results elucidated a novel pathway in NDRG2-mediated inhibition of cholangiocarcinogenesis and metastasis and suggest new therapeutic targets, including NDRG2, LIF, miR-181c, and transforming growth factor beta, in cholangiocarci prevention and treatment (Homo sapiens) PubMed

 27534.

lncRNA MVIH was upregulated in glioma cell lines and tissues; patients with MVIH high expression tumors had a worse overall survival; up-regulation of MVIH expression promoted glioma cells proliferation, invasion and migration, while down-regulation of MVIH expression suppressed these processes [lncRNA MVIH] (Homo sapiens) PubMed

 27535.

findings showed that the expression of lncRNA HMlincRNA717 was down-regulated in pancreatic cancer and associated with overall survival, suggesting that HMlincRNA717 could be a potential prognostic biomarker for pancreatic cancer progression [HMlincRNA717] (Homo sapiens) PubMed

 27536.

Upregulation of SNHG6 regulates ZEB1 expression by competitively binding miR-101-3p and interacting with UPF1 in hepatocellular carcinoma, promoting tumor growth and metastasis. (Homo sapiens) PubMed

 27537.

When the prognostic impacts of pre- and post-operative serum CA19-9, SPan-1, and DUPAN-II levels in patients with resectable pancreatic ductal adenocarcinoma were compared, elevated postoperative CA19-9 was the strongest predictive marker of poor survival in the pre- and post-operative period. [CA19-9, SPan-1 and DUPAN-II] (Homo sapiens) PubMed

 27538.

Elevated serum SPan-1 was associated with lymph node metastasis in this cohort of patients who underwent resection for invasive intraductal papillary mucinous neoplasms of the pancreas. [SPan-1] (Homo sapiens) PubMed

 27539.

GATA1 is an essential downstream target of SENP1 and that the differential expression and response of GATA1 and Bcl-xL are a key mechanism underlying chronic mountain sickness pathology. (Homo sapiens) PubMed

 27540.

Elevation of CA 19-9 is associated with decreased stage-specific survival in pancreatic ductal adenocarcinoma (PDAC), with the greatest difference in early stages. Patients with PDAC who have elevated CA 19-9 levels at diagnosis are biologically borderline resectable regardless of anatomic resectability, and neoadjuvant systemic therapy is suggested. [CA 19-9] (Homo sapiens) PubMed

 27541.

Long non-coding RNA 91H is overexpressed in breast cancer and 91H-induced epigenetic modifications on H19/IGF2 locus suggest that 91H may play essential role in breast cancer development. (Homo sapiens) PubMed

 27542.

Circular RNA circHIAT1 functionss a metastatic inhibitor to suppress AR-enhanced ccRCC cell migration and invasion via miR-195-5p/29a-3p/29c-3p/CDC42 signaling pathway. (Homo sapiens) PubMed

 27543.

These results conclude that the new long isoform of PLAAT-1 is a calcium-independent N-acyltransferase existing in both cytoplasm and nucleus and suggest a possible formation of NAPEs in various membrane structures including nuclear membrane. (Homo sapiens) PubMed

 27544.

mirn199 microRNA, human. Overall, this study reveals a novel SRF-miR-199a/miR-214-E-cadherin/claudin-2 axis that mediates damage and fibrosis in PD (Homo sapiens) PubMed

 27545.

LncRNA LOC90784 was overexpressed in hepatocellular carcinoma tissues and cell lines. Highly expressed lncRNA LOC90784 was associated with poor clinical features in hepatocellular carcinoma. [LncRNA LOC90784 ] (Homo sapiens) PubMed

 27546.

Our study discovers that hsa_circ_0001564 acts as miR-29c-3p sponge to mediate the tumorigenicity, which could act as a potential biomarker for the osteosarcoma and provide a novel insight for competing endogenous RNA mechanism in osteosarcoma. (Homo sapiens) PubMed

 27547.

This review discusses previous studies to provide comprehensive information on the physiological role of cyclophilin D as well as mitochondrial permeability transition pore (PTP) opening in the cell that can be taken into consideration for the development of new PTP inhibitors. [mitochondrial permeability transition pore ] [review] (Homo sapiens) PubMed

 27548.

This study demonstrated that mitochondrial MRP-1 is expressed in the outer mitochondrial membrane and is a client protein of HSP90beta.[HSP90beta] (Homo sapiens) PubMed

 27549.

AS-RBM15 is a regulator of megakaryocyte differentiation and may play a regulatory role in leukemogenesis. (Homo sapiens) PubMed

 27550.

These results suggest that the p38/NPM/PP2A (protein phosphatase 2) complex acts as a dynamic sensor, allowing endothelial cells to react rapidly to acute oxidative stress.[PP2A] (Homo sapiens) PubMed

 27551.

Therefore, a DLODP activity showing selectivity toward lipophilic diphosphodiesters such as DLO, and possessing properties distinct from other lipid phosphatases, is identified. Separate subcellular locations for DLODP action and DLO biosynthesis may be required to prevent uncontrolled DLO destruction (Homo sapiens) PubMed

 27552.

The association of mitochondrial microphthalmia-associated transcription factor (MITF) with pyruvate dehydrogenase (PDH) emerges as an important regulator of mast cell function. Our findings indicate that PDH could arise as a new target for the manipulation of allergic diseases [microphthalmia-associated transcription factor] (Homo sapiens) PubMed

 27553.

p53 and synthetic PIF pathways could interact in human trophoblast and thus promotes cell survival.[PIF] (Homo sapiens) PubMed

 27554.

complete blocking of CRLs at a higher inhibitor dose-induced cytotoxicity that was amplified by knockdown of CRL regulator Cand1.[CRL] (Homo sapiens) PubMed

 27555.

Ik6, the upstream factor of Akt-FoxO1 pathway, can protect acute lymphoblastic leukemia cells against daunorubicin-induced apoptosis.[Ik6] (Homo sapiens) PubMed

 27556.

PML/RARalpha synergizes with C/EBPepsilon to reactivate the C/EBPepsilon target G0S2, thereby contributing to All-trans retinoic acid -mediated acute promyelocytic leukemia differentiation and potentially, clinical remission.[PML-RARalpha] (Homo sapiens) PubMed

 27557.

Conserved LxxIxE motif PP2A-B56alpha protein determine binding specificity and phosphorylation status of substrates. (Homo sapiens) PubMed

 27558.

cyclin D1 and other cyclins such as cyclin A regulates DNA integrity through RAD51 interaction with the BRCA2 C-terminal domain [cyclin b] (Homo sapiens) PubMed

 27559.

These results indicate a protective role for miR-124 through the inhibition of SMOX-mediated DNA damage in the etiology of H. pylori-associated gastric cancer. (Homo sapiens) PubMed

 27560.

found miR-196a-2 rs11614913 and miR-499 rs3746444 were associated with ulcerative colitis in north Indian population [microRNA-196a] (Homo sapiens) PubMed

 27561.

Ribosomal 40S protein ubiquitylation plays a pivotal role in mammalian ribosome-associated quality control pathways. (Homo sapiens) PubMed

 27562.

Plasma presepsin level is a reliable marker of febrile neutropenia even in massive chemotherapy with very low white blood cell counts. [presepsin] (Homo sapiens) PubMed

 27563.

Long noncoding RNA HBL1 counteracts MIR1 to regulate cardiomyocyte differentiation. (Homo sapiens) PubMed

 27564.

Interleukin 35 could mediate anti-inflammatory function through promoting regulatory B cell functions, but this effect was suppressed in Ulcerative Colitis patients.[IL35, human] (Homo sapiens) PubMed

 27565.

Data suggest ERBB2 is post-transcriptionally increased in tamoxifen-resistant estrogen receptor-positive breast cancer cells; ERBB2 expression is decreased post-transcriptionally by MIR26a/b binding to 3'-untranslated region (UTR); ERBB2 expression is increased post-transcriptionally by HuR binding to 3'-UTR. (ERBB2 = epidermal growth factor receptor 2; HuR = Hu antigen R) [MIR26a, microRNA 26a; MIR26b, microRNA 26b] (Homo sapiens) PubMed

 27566.

The alternative splicing of lncRNA-PXN-AS1 by MbLN3 splicing factor promotes hepatocellular carcinoma by increasing paxillin expression. (Homo sapiens) PubMed

 27567.

APF binds specifically to sites within the cytoskeleton-associated protein 4 (CKAP4) extracellular domain [APF] (Homo sapiens) PubMed

 27568.

The biological heterogeneity of BCR-ABL1-positive childhood acute lymphoblastic leukemia may impact the patient outcomes and optimal treatment.[BCR-ABL1] (Homo sapiens) PubMed

 27569.

our results established that tRNA-derived fragments /miR-1280 suppresses colorectal cancer growth and metastasis by repressing Notch signaling pathways that support cancer stem-like cells phenotypes (Homo sapiens) PubMed

 27570.

Pretreatment with the soluble ErbB3 N418Q mutant suppressed heregulin beta1-induced HIF-1alpha activation in MCF7 cells. [heregulin beta1] (Homo sapiens) PubMed

 27571.

In our study, we found a novel lncRNA PILRLS (Proliferation Interacting LncRNA in Retroperitoneal Liposarcoma), which as an oncogene significantly overexpressed in retroperitoneal liposarcoma (Homo sapiens) PubMed

 27572.

VELUCT is the first example for a long non-coding RNAs that is expressed at a very low level, but has a strong loss-of-function phenotype.[VELUCT] (Homo sapiens) PubMed

 27573.

The mean preoperative fecal elastase-1 levels were higher (odds ratio = 1.003, p = 0.034) in the pancreatic fistula patients than other patients. [fecal elastase-1] (Homo sapiens) PubMed

 27574.

BCR signaling differs between the germinal center B-cell (GCB) subtype of diffuse large B-cell lymphoma, which is insensitive to Bruton tyrosine kinase inhibition by ibrutinib, and the activated B-cell (ABC) subtype.[BCR] (Homo sapiens) PubMed

 27575.

increased FOXO1 represents a critical mechanism driving aberrant self-renewal in preleukemic cells expressing the t(8;21)-associated oncogene AML1-ETO.[AML1-ETO] (Homo sapiens) PubMed

 27576.

inhibition of endogenous miR-26a promoted proliferation and restoration of mature miR-26a inhibited the proliferation of human lung fibroblasts [mir26] (Homo sapiens) PubMed

 27577.

Data, including data from studies using recombinant fusion forms of GSDMD (gasdermin D), suggest that GSDMD participates in inflammasome-dependent pyroptosis of macrophages in response to various stimuli; this mechanism involves proteolysis of GSDMD by caspase-1 and caspase-11. [CASP11, caspase-11] (Homo sapiens) PubMed

 27578.

defective self-renewal ability and leukemogenesis of MLL-Af4 myeloid cells could contribute to the strong B-cell acute lymphoblastic leukemia association of MLL-AF4 leukemia.[MLL-Af4] (Homo sapiens) PubMed

 27579.

the membrane-associated estrogen receptor ER-alpha36 signaling, but not the G protein-coupled estrogen receptor 1 (GPER1) signaling, might be involved in the Tamoxifen resistance and metastasis of breast cancer cells. (Homo sapiens) PubMed

 27580.

The iron-rich regions existed in ovarian endometrial cysts concomitantly with the high level of IRP2 expression, which should generally be decomposed upon an overload of iron. (IRP2 protein, human) (Homo sapiens) PubMed

 27581.

TNBC-associated biomarker miR-199a-5p conferred tumor-suppressive role in breast cancer by regulating EMT process and stemness characteristics. (Homo sapiens) PubMed

 27582.

Lnc34a recruits Dnmt3a via PHB2 and HDAC1 to methylate and deacetylate the miR-34a promoter simultaneously, hence epigenetically silencing miR-34a expression independent of its upstream regulator, p53.[Lnc34a] (Homo sapiens) PubMed

 27583.

FBXW-185aa inhibited the expression of c-Myc, thus decreasing cellular proliferation and inhibiting cell cycle acceleration. [FBXW7-185aa] (Homo sapiens) PubMed

 27584.

These results suggest that miR1934 is an important anti-inflammatory factor and may represent a novel mechanism for controlling adipose tissue inflammation.[miR1934] (Homo sapiens) PubMed

 27585.

This study suggests that erythrocyte ADMA accumulation contributes to impaired response to erythropoietin in predialysis patients via suppression of erythropoietin receptor expression. [Asymmetric Dimethylarginine] (Homo sapiens) PubMed

 27586.

Glyoxalase 2 expression in prostate cancer was dependent on androgen receptor and was aimed at stimulating cell proliferation and eluding apoptosis through a mechanism involving the p53-p21 axis (Glyoxalase 2) (Homo sapiens) PubMed

 27587.

CX3CL1 is upregulated in both human and murine tumors following VEGF signaling blockade, resulting in recruitment of CX3CR1+Ly6Clo monocytes into the tumor [lY6C1] (Homo sapiens) PubMed

 27588.

WiNTRLINC1 interacts with TCF4/beta-catenin to mediate the juxtaposition of its promoter with the regulatory regions of ASCL2.[WiNTRLINC1] (Homo sapiens) PubMed

 27589.

Consistent with these observations, we found 5 aza-cytadine to relieve the suppression of miRNA-29c[miRNA 29c] (Homo sapiens) PubMed

 27590.

AKT/GSK-3beta-mediated stabilization of SP1 is required for TGF-beta induced up-regulation of NKG2DLs.[NKG2DL] (Homo sapiens) PubMed

 27591.

A previously uncharacterized lincRNA, SLINKY (Survival-predictive LINcRNA in KidneY cancer), was the top-ranked prognostic lincRNA, and validated as a prognostic biomarker in clear cell renal cell carcinomas (Homo sapiens) PubMed

 27592.

miR-181a could act as a tumor suppressor in pediatric ALL with over expression of its target pair, Smad7. (Homo sapiens) PubMed

 27593.

miR-182 overexpression in the inflammatory microenvironment resulted in an imbalance in the lncRNA-POIR-miR-182 regulatory network.[lncRNA-POIR] (Homo sapiens) PubMed

 27594.

Monocyte lncRNA OTTHUMT00000387022 is novel and specific marker of coronary artery disease. (Homo sapiens) PubMed

 27595.

results showed that key components of the Hippo signaling pathway are aberrantly expressed and associated with the malignant potential of human intrahepatic cholangiocarcinoma [hippo] (Homo sapiens) PubMed

 27596.

Transfection of miR-449a, miR-449b, and/or miR-449c inhibited cell proliferation and migration, induced apoptosis, and reduced tumor growth to different extents[ miR-449b, and miR-449c] (Homo sapiens) PubMed

 27597.

We report two teenagers with ID whose molecular diagnosis of a SMARC2A or ARID1B mutation, respectively, was established through clinical exome analysis. (Homo sapiens) PubMed

 27598.

Serum miR-92a-3p levels were significantly higher in children with Kawasaki disease and were associated with coronary artery lesions. (Homo sapiens) PubMed

 27599.

CA19.9 appears as a physiological product whose synthesis strongly depends on the tissue specific and epigenetically-regulated expression of B3GALT5 and ST3GAL3.[CA19.9] (Homo sapiens) PubMed

 27600.

We provide evidence that the downregulation of hsa-miR-124-3p, hsa-miR-129-5p and hsa-miR-378 induced an increase in both expression and activity of CPT1A, CACT and CrAT in malignant prostate cells. (Homo sapiens) PubMed

 27601.

lncRNA-CIR significantly up-regulated in Osteoarthritis patients, concomitantly down-regulated miR-27 and up-regulated MMP13. [Long Noncoding RNA CIR] (Homo sapiens) PubMed

 27602.

both immunoglobulins did not bind key epitope of CA19.9 glycoprotein, tetrasaccharide SiaLe(A), as well as its defucosylated form sialyl Le(C) (known as CA-50 epitope). (Homo sapiens) PubMed

 27603.

This report documents a novel lncRNA, GClnc1, which may act as a scaffold to recruit the WDR5 and KAT2A complex and modify the transcription of target genes. This study reveals that GClnc1 is an oncogenic lncRNA in human gastric cancer. (Homo sapiens) PubMed

 27604.

Our study suggests that miR-219-5p regulated the proliferation, migration, and invasion of human gastric cancer cells by suppressing LRH-1. (Homo sapiens) PubMed

 27605.

Snd2 protein represents an alternative targeting factor to the endoplasmic reticulum in human cells. [Snd2] (Homo sapiens) PubMed

 27606.

a mechanistic link between UTX-1 and enhanced HIV-1 replication [UTX-1] (Homo sapiens) PubMed

 27607.

identified 15 CpG sites within the APC 1A promoter that were significantly hypermethylated and 14 CpG loci within the NFATC1 gene body that were significantly hypomethylated (pLIS < 1 x 10(-5) ) in the tumours of active smokers [APC 1A] (Homo sapiens) PubMed

 27608.

RP1-13D10.2 is a long noncoding RNA that regulates LDLR and may contribute to low-density lipoprotein cholesterol response to statin treatment. (Homo sapiens) PubMed

 27609.

siRNA mediated knock-down of LRP is recommended as a potential therapeutic avenue for the treatment of pancreatic cancer and neuroblastoma. [LRP/LR protein or Laminin receptor, human] (Homo sapiens) PubMed

 27610.

MiR-23 played a key role in High glucose-induced epithelial-mesenchymal transition of human mesothelial peritoneal cells by targeting VDR. [MiR23 microRNA, human] (Homo sapiens) PubMed

 27611.

Results identified one oestrogen-repressed lncRNA gene (BC041455) and one oestrogen-induced lncRNA gene (CR593775). These two primate-specific oestrogen-regulated lncRNAs exert strong and reproducible effects on cell viability, cell growth and cell death of human breast cancer cells. [lncRNA CR593775] (Homo sapiens) PubMed

 27612.

lncRNA-HIT plays an important role in metastasis in NSCLC. LncRNA-HIT promotes cell migration and invasion at least in part through interaction with ZEB1 regulating its expression. (Homo sapiens) PubMed

 27613.

MLL-AF4 spreading gene expression is downregulated by inhibitors of the H3K79 methyltransferase DOT1L.[MLL-AF4] (Homo sapiens) PubMed

 27614.

Data suggest that modulation of microRNA 19a/b by dietary factors can be used in cancer prevention/treatment; here, grape seed procyanidin extract (GSE) dietary supplement down-regulates microRNA 19a/b in non-small-cell lung carcinoma (NSCLC) cell lines and prevents tumor growth in NSCLC xenograft model. [MIR19, microRNA 19] (Homo sapiens) PubMed

 27615.

ERG, FLI1, TAL1, and RUNX1 bind at all AML1-ETO-occupied regulatory regions, including those of the AML1-ETO gene itself, suggesting their involvement in regulating AML1-ETO expression levels.[AML1-ETO] (Homo sapiens) PubMed

 27616.

Aberrant ANK1 methylation is highly prevalent in lung cancer, discriminate tumors by histology and patients' smoking history, and contributes to miR-486-5p repression. (Homo sapiens) PubMed

 27617.

MIR-720 suppresses M2 macrophage polarization by targeting GATA3; MIR-720 is down-regulated in breast cancer macrophages. [MIR-720] (Homo sapiens) PubMed

 27618.

Data found an obvious increase in uc.187 expression in patients with severe preeclampsia leading to an aberrant biological behavior of the trophoblastic HTR-8/SVneo cell line. (Homo sapiens) PubMed

 27619.

Role of 14-3-3eta protein on cardiac fatty acid metabolism and macrophage polarization after high fat diet induced type 2 diabetes mellitus [14-3-3eta] (Homo sapiens) PubMed

 27620.

BAFF has a role in inducing IL35 production by regulatory B cells in lupus [il35] (Homo sapiens) PubMed

 27621.

STRO-1 binds to immune-precipitated HSC70 and siRNA-mediated knock down of HSPA8 reduced STRO-1 binding.[STRO-1] (Homo sapiens) PubMed

 27622.

a Novel Long Noncoding RNA with role in reduced Pbx1 expression, cardiomyocyte induction and potential pathological factor for ventricular septal defect (Homo sapiens) PubMed

 27623.

Non-normalization of CA19-9 level after resection of biliary tract cancer with curative intent was associated with worse overall survival. R1 resection was associated with a particularly poor prognosis when CA19-9 levels did not normalize. [carbohydrate antigen 19-9] (Homo sapiens) PubMed

 27624.

QKI-5 was found to be an important regulator of STAT3 stabilization and vascular endothelial growth factor receptor 2 (VEGFR2) activation during the endothelial cell differentiation process.[QKI-5] (Homo sapiens) PubMed

 27625.

These findings revealed that miR-138 might promote angiogenesis of human cytomegalovirus (HCMV)-infected HUVECs by activating the SIRT1-mediated p-STAT3 pathway, and this could provide novel insights into HCMV-induced angiogenesis.[miR-138] (Homo sapiens) PubMed

 27626.

increased CRMP4 expression mediated by the activation of VEGF signaling facilitates gastric tumor growth and metastasis, which may have clinical implications associated with a reduced survival rate in gastric cancer patients (Homo sapiens) PubMed

 27627.

the concomitant decrease of QKI5 releases Microprocessor from pri-124-1 and reduces mature miR-124 levels to facilitate erythrocyte maturation.[QKI5] (Homo sapiens) PubMed

 27628.

Both elevated serum CEA and CA 19-9 levels were associated with the presence of advanced colorectal neoplasia, as well as colorectal cancer.[CEA, CA19-9] (Homo sapiens) PubMed

 27629.

The effects of LncRNA DQ786243 were assessed by silencing the LncRNA in vitro and in vivo Results showed that the expression level LncRNA DQ786243 was significantly higher in colorectal cancer tissues and cell lines. [LncRNA DQ786243] (Homo sapiens) PubMed

 27630.

Mitogen activated protein kinase 1 (MAPK1) was significantly up-regulated, while miR-422a was down-regulated in thyroid cancer cells cultured with high iodine; miR-422a directly bound to the 3'UTR of MAPK1 mRNA. [miR-422a] (Homo sapiens) PubMed

 27631.

The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and genetic translation in tumor cells. (Homo sapiens) PubMed

 27632.

Study have demonstrated that a novel lncRNA, lnc-GNAT1-1, is low expressed in colorectal cancer tissues and plasma, and acts as a tumor suppressor through regulating RKIP-NF-kappaB-Snail circuit. [lnc-GNAT1-1] (Homo sapiens) PubMed

 27633.

The MUC1 possessing the T (Galbeta1-3GalNAcalpha1-Ser/Thr) or ST antigen (NeuNAcalpha2-3Galbeta1-3GalNAcalpha1-Ser/Thr) failed to show self-interactions. (MUC1 protein) (Homo sapiens) PubMed

 27634.

miR-486-5p inhibits non-small cell lung cancer progression by down-regulating the expression of CDK4. (Homo sapiens) PubMed

 27635.

MiR-133 directly targeted and down-regulated FOXQ1 expression, which in turn reduced TGF-beta level. MiR-133 was down-regulated in lung cancer cell lines A549 and HCC827, and its re-expression significantly inhibited the migration and invasion of the lung cancer cells. miR-133 induced elevation of epithelial marker E-cadherin, and reduction of mesenchymal marker Vimentin. mir133. (Homo sapiens) PubMed

 27636.

Results show that ATB is abnormally up-regulated both in glioma tissues and cell lines compared with normal brain tissues. Its knockdown significantly inhibits glioma malignancy, including cell proliferation, colony formation, migration, invasion in vitro, and the xenograft tumor formation in vivo. Also, ATB was confirmed to target miR-200a. [LncRNA-ATB] (Homo sapiens) PubMed

 27637.

Epithelial and plasma miR-181b-5p are potential biomarkers for airway eosinophilia in asthma. (Homo sapiens) PubMed

 27638.

MOTS-c has been shown to target the skeletal muscle and enhance glucose metabolism. As such, MOTS-c has implications in the regulation of obesity, diabetes, exercise, and longevity, representing an entirely novel mitochondrial signaling mechanism to regulate metabolism within and between cells. [REVIEW] (Homo sapiens) PubMed

 27639.

Ectopic expression of human THOR in zebrafish accelerated the onset of melanoma. THOR represents a novel class of functionally important cancer/testis lncRNAs whose structure and function have undergone positive evolutionary selection. [THOR, testis-associated highly conserved oncogenic long non-coding RNA] (Homo sapiens) PubMed

 27640.

GIHCG epigenetically silences miR-200b/a/429 expression. (Homo sapiens) PubMed

 27641.

miR-7-5p is a potent inhibitor of melanoma growth and metastasis, in part through its inactivation of RelA/NF-kappaB signaling. (Homo sapiens) PubMed

 27642.

Transfections of undifferentiated shed cells with miR-450a-5p or miR-28-5p mimics or with miR-450a-5p or miR-28-5p antagonists demonstrated that these miRNAs might play a role as posttranscriptional controllers of STAT1 mRNA during osteoblastic differentiation. (Homo sapiens) PubMed

 27643.

This study aimed to further investigate the association with HLA-A*31:01 besides HLA-B*15:02 in a multiethnic Malaysian population.[HLA-A*31:01, HLA-B*15:02] (Homo sapiens) PubMed

 27644.

we have identified a piR-651 as a potential biomarker that can be detected in serum of classical Hodgkin lymphoma patients indicating that the Piwi/piwiRNA pathway is active in this disease (Homo sapiens) PubMed

 27645.

modulation of proteostasis is a distinct biological function of sAPPalpha and does not require surface-bound holo-APP.[sAPPalpha] (Homo sapiens) PubMed

 27646.

Long noncoding RNA DANCR promotes prostate cancer invasion and metastasis through repressing the expression of TIMP2/3 [Long noncoding RNA DANCR] (Homo sapiens) PubMed

 27647.

Lnc-CC3 promoted migration and invasion in cervical cancer cells by increasing Slug expression; lnc-CC3 may be useful marker of metastases in cervical cancer. [lnc-CC3, human; accession#KT832804] (Homo sapiens) PubMed

 27648.

a major function of macroH2A histone variants is to link nucleosome composition to higher-order chromatin architecture.[MacroH2A] (Homo sapiens) PubMed

 27649.

elevated D-dimer plasma levels were independent predictors for Deep venous thrombosis in Chinese patients with intracerebral hemorrhage.[D-Dimer] (Homo sapiens) PubMed

 27650.

MIRN106 microRNA, human. MiR-106a as an oncogene could promote proliferation and metastasis of prostate cancer cells by directly targeting PTEN in vivo and in vitro (Homo sapiens) PubMed

 27651.

small magnitude of the age effect suggests that inter-individual factors other than age likely contribute to a higher degree to KAL9 and KAL12 expression[Kalirin-9 and Kalirin-12 ] (Homo sapiens) PubMed

 27652.

it was suggested that miR-19, upregulated in osteosarcoma cells, negatively regulated the expression of Pax6, which can promote the malignant phenotypes of osteosarcoma cells via activation of the extracellular signal-regulated kinase signaling pathways (Homo sapiens) PubMed

 27653.

we have identified lnc-RI as a new regulator of mitosis which acts by releasing PLK1 mRNA activity via competition for binding to miRNA-210-3p. (Homo sapiens) PubMed

 27654.

These findings identify a novel role for HIV-1 TAR in the absence of Tat, involving the interference with host cellular immune responses by targeting 7SK RNA-mediated gene expression and P-TEFb inactivation.[P-TEFb] (Homo sapiens) PubMed

 27655.

The immunoglobulin D Fc receptor (FcdeltaR) is expressed on fibroblast like synoviocytes obtained from rheumatoid arthritis patients and contributes to their activation. (Homo sapiens) PubMed

 27656.

In this study we report an apparent synergy between TGF-beta1 and Hsp90B in stimulating migratory behaviour of colon cancer cells when signalling occurs via alphav beta6 integrin as opposed to the canonical TGF-beta1 pathway. (Homo sapiens) PubMed

 27657.

negatively expressed relative to Il-18 in psoriatic lesional skin [Erdr1] (Homo sapiens) PubMed

 27658.

By ubiquitylating and degrading NOXA through activating CRL5, UBE2F selectively promotes lung cancer cell survival and could, therefore, serve as a novel cancer target (Homo sapiens) PubMed

 27659.

LncRNA-AK058003 can reduce the expression of mRNA stabilizing protein HuR and act as a precursor of miR-15a to suppress gamma-synuclein-mediated cell proliferation and the metastasis of hepatocellular carcinoma. (Homo sapiens) PubMed

 27660.

identified four miRNAs, miR-19, miR-340, miR-374 and miR-542 that bind to the 3'-UTR of the MID1 mRNA. These miRNAs not only regulate MID1 expression but also mTOR signaling and translation of disease associated mRNAs and could therefore serve as potential drugs for future therapy development [mir19] [mir374] (Homo sapiens) PubMed

 27661.

Helicobacter pylori infection related long noncoding RNA (lncRNA) AF147447 has a role in the suppression of gastric carcinogenesis. (Homo sapiens) PubMed

 27662.

Data suggest that hypothyroidism delays pubertal onset via up-regulation of expression of hypothalamic GnIH (gonadotropin-inhibitory hormone) and down-regulation of circulating gonadotropin and estradiol levels. [REVIEW] [GnIH, gonadotropin-inhibitory hormone] (Homo sapiens) PubMed

 27663.

MiR-29 plays an important role in fibrosis through direct suppression of a variety of extracellular matrix expression proteins and is also involved in the regulation of multiple signaling pathways. [MiR-29 ][review] (Homo sapiens) PubMed

 27664.

lncRNAs play a critical role in the osteogenic differentiation of hBMMSCs and targeting lncRNA ENST00000502125.2 might be a promising strategy to promote osteogenic differentiation (Homo sapiens) PubMed

 27665.

RUNX1-EVI1 directs a stem cell-like transcriptional network reliant on GATA2, whereas that of RUNX1-ETO-expressing cells is more mature and depends on RUNX1.[RUNX1-ETO, RUNX1-EVI1] (Homo sapiens) PubMed

 27666.

Combining measurements of sweyjawbu expression and the ratio of the 5' and 3' portions of the ALK transcript provided accurate identification of ALK rearrangement-positive lymphomas. (Homo sapiens) PubMed

 27667.

NONHSAT076754 promotes migration and invasiveness of papillary thyroid cancer and serves as a valuable auxiliary biomarker that can be used along with ultrasonography in the prediction of cervical Lymph node metastasis. (Homo sapiens) PubMed

 27668.

Suggest role for lncRNA, RP11-137H2.4 in resistance of childhood acute lymphoblastic leukemia to prednisolone treatment. (Homo sapiens) PubMed

 27669.

The decreased miR-101-3p caused elevated Bim expression by targeting its 3'-untranslated region (3'-UTR).[miR101-3p] (Homo sapiens) PubMed

 27670.

our data strongly suggest that activin A-induced signalling plays a critical role in hair follicle neogenesis. [Activin A] (Homo sapiens) PubMed

 27671.

These results provide several pieces of evidence to prove that overexpression of miR-128 is able to reverse the gefitinib-resistant lung cancer stem cells by inhibiting the c-met/PI3K/AKT pathway (Homo sapiens) PubMed

 27672.

Circulating level of IL-39 might be a predictor of cardiac systolic dysfunction in ST-segment elevation myocardial infarction patients [IL-39] (Homo sapiens) PubMed

 27673.

Since RP11-19P22.6-001 acts in cis to regulate nitric oxide synthase 2 (NOS2), we also analyzed NOS2 expression and its correlation with gastric cancer. The combined use of lncRNAs and their target genes may be a promising method to increase the diagnostic value of lncRNAs in cancer (Homo sapiens) PubMed

 27674.

MiR-9-5p downregulates SLC20A2 in HEK293 cells. (Homo sapiens) PubMed

 27675.

miR-199a-3p could increase cisplatin sensitivity of cholangiocarcinoma cell lines by inhibiting the activity of the mTOR signaling pathway and decreasing the expression of MDR1. (Homo sapiens) PubMed

 27676.

In multivariate analysis, no liver metastasis, CA19-9 level <250 IU/ml and localized or locally advanced cancer at diagnosis were good prognostic factors. According to a clinical score based on these features, overall survival was 7.7, 13.5, 19.7 and 21.0 months, respectively (Homo sapiens) PubMed

 27677.

Research identified that LncRNA NONHSAG026900 was significantly down-regulated in diffuse large B-cell lymphoma (DLBCL) samples, and could serve as a favorable biomarker to predict prognosis of DLBCL patients. [LncRNA NONHSAG026900] (Homo sapiens) PubMed

 27678.

Our studies provide clear evidence to support LincIN as a new regulator of tumor progression-metastasis at both transcriptional and translational levels and as a promising prognostic biomarker for breast cancer. (Homo sapiens) PubMed

 27679.

the combination of THBS2 and CA19-9 yielded a sensitivity of 87% for pancreatic ductal adenocarcinoma in the phase 2b study.[CA19-9] (Homo sapiens) PubMed

 27680.

we demonstrate that lncRNA CTA is an essential regulator in DOX-induced OS cell apoptosis, and the lncRNA CTA-miR-210 axis plays an important role in reducing OS chemoresistance. (Homo sapiens) PubMed

 27681.

the level of miR526a was downregulated in HCC tissues and wellestablished cell lines. In addition, the ectopic introduction of miR526a into Huh7 and HepG2 cells significantly attenuated HCC tumorigenesis, including proliferation, migration and invasion. The growth of tumor xenografts was also inhibited following transfection with miR526a. (Homo sapiens) PubMed

 27682.

miR-3622a is a novel prostate cancer (PCa) biomarker and potential drug target for developing therapeutic regimens against advanced PCa.[miR3622a] (Homo sapiens) PubMed

 27683.

The results of our study highlight linc-NeD125 as a key player in G4 MB driver gene network and as a novel member of the small but growing list of lncRNAs implicated in human cancerogenesis via the ceRNA mechanism. (Homo sapiens) PubMed

 27684.

Long noncoding RNA-ATB functions as a molecular sponge for miR-200b and Kindlin-2.[Lncrna ATB] (Homo sapiens) PubMed

 27685.

lncRNA CHRF-induced miR-489 loss facilitates metastasis and EMT process of CRC cells probably via TWIST1/EMT signaling pathway. (Homo sapiens) PubMed

 27686.

MiR-4653-3p and its target gene FRS2 are may have roles in response of hormone receptor positive breast cancer patients to tamoxifen [MiR-4653-3p] (Homo sapiens) PubMed

 27687.

RCE1 acts as a tumor suppressor in CRC, as its reduced expression may increase CRC cell invasion and independently predict an unsatisfactory prognosis in CRC patients. (Homo sapiens) PubMed

 27688.

Lnc RNA AC067945.2 overexpression was correlated with developmental processes, binding, extracellular region, and the vascular endothelial cell growth factor (VEGF) and Wnt signalling pathways. (Homo sapiens) PubMed

 27689.

A combination of low 14-3-3sigma and high LASP1 expression shows a worse trend with overall survival of colorectal cancer patients.[14-3-3 omega] (Homo sapiens) PubMed

 27690.

miR-516a-5p may regulate MTHFR, MMP-2, and TIMP-1 expressions in vascular smooth muscle cells, possibly promoting the disruption of homocysteine metabolism and proteolytic degradation of elastin for abdominal aortic aneurysm formation. (Homo sapiens) PubMed

 27691.

This study identified PDIA3P as a novel c-Myc interacting long noncoding RNA.[PDIA3p] (Homo sapiens) PubMed

 27692.

Results showed that blocking miR-31 led to an increase in osterix protein in both cell types at day 7, with an increase in osteocalcin at day 21, suggesting MSC osteogenesis [osteocalcin] (Homo sapiens) PubMed

 27693.

elevated Tn levels in cancer and inflammation may be commonly regulated by the cytokine (TNFa and IL6)-Cosmc signaling axis [Tn antigen (CD175 protein)] (Homo sapiens) PubMed

 27694.

The results demonstrated that the hsa_circ_0046701/miR-142-3p/ITGB8 axis might play critical regulatory roles in the pathogenesis and development of glioma.[hsa_circ_0046701] (Homo sapiens) PubMed

 27695.

results also provide evidence of Humanin playing a pivotal role in protecting cells with Age-related macular degeneration mitochondria. (Homo sapiens) PubMed

 27696.

RP11-708H21.4 expression was aberrantly decreased in colorectal cancer (CRC), and its expression was closely associated with aggressive clinicopathologic features and unfavorable prognosis of CRC patients. [RP11-708H21.4] (Homo sapiens) PubMed

 27697.

The present study demonstrated a negative association between the expression of miR75p and TFF3 in IBD lesional tissues and normal tissues. In conclusion, TFF3 was identified as a novel target of miR75p (Homo sapiens) PubMed

 27698.

The flow-mediated miR-10a expression is regulated by Kruppel-like factor 2 through modulation in RARalpha-RARE binding, with the consequent regulation in GATA6/VCAM-1 in endothelial cells. (Homo sapiens) PubMed

 27699.

circMAN2B2 demonstrated that circMAN2B2 acts as an oncogenic role in lung cancer through promoting FOXK1 expression by sponging miR-1275[circMAN2B2] (Homo sapiens) PubMed

 27700.

these results indicated that coronin3 is significantly dysregulated in hepatocellular carcinoma tumor tissues, and may exert its function via regulating G6PC3 expression.[Coronin 3] (Homo sapiens) PubMed

 27701.

PI3K and PIKK have roles in radioresistance in thyroid carcinomas [PIKK] (Homo sapiens) PubMed

 27702.

lncRNA EBF3-AS promotes neuron apoptosis in AD, and involved in regulating EBF3 expression. [EBF3-AS] (Homo sapiens) PubMed

 27703.

CircRNA_100876 is closely related to the carcinogenesis of non small cell lung cancer (NSCLC) and it might be served as a potential prognostic biomarker and therapeutic target for NSCLC. [CircRNA_100876] (Homo sapiens) PubMed

 27704.

These findings demonstrate the relative safety of CART72 cells. The limited persistence supports the incorporation of co-stimulatory domains in the CAR design and the use of fully human CAR constructs to mitigate immunogenicity (Homo sapiens) PubMed

 27705.

miR-194 and -515 is the key mediator between inflammatory cytokines and CS synthesis which demonstrated a new regulatory circuitry in IDD pathogenesis, and also gave evidence that microRNAs are also important regulators in intervertebral disc degeneration. (Homo sapiens) PubMed

 27706.

Data report that SUMO5, a novel SUMO variant, mediates the growth and disruption of Promyelocytic leukemia nuclear bodies (PML-NBs). PolySUMO5 conjugation of PML at lysine 160 facilitates recruitment of PML-NB components, which enlarges PML-NBs. SUMO5 also increases polySUMO2/3 conjugation of PML, resulting in RNF4-mediated disruption of PML-NBs. [SUMO5] (Homo sapiens) PubMed

 27707.

we showed that microRNA -196a-3p is decreased by transforming growth factor-beta1 in breast cancer cells and associated with breast cancer progression. (Homo sapiens) PubMed

 27708.

hsa_circ_0067934 is upregulated in Esophageal squamous cell carcinoma tumor tissue.[ hsa_circ_0067934] (Homo sapiens) PubMed

 27709.

miR-133a inhibits proliferation and induces apoptosis of gastric cancer cells by downregulating the expression of ERBB2 and its downstream signaling molecules p-ERK1/2 and p-AKT (Homo sapiens) PubMed

 27710.

miR-135a-5p can suppress cell progress including cell proliferation, migration, and invasion in thyroid carcinoma by targeting VCAN 3'-UTR. (Homo sapiens) PubMed

 27711.

All urine samples were analyzed by voided urine and bladder washing cytology, NMP22 and UBC rapid test (qualitatively and quantitatively). The best cutoff (highest Youden index; >/=6.7 ng/ml) for the quantitative UBC was determined by receiver operating characteristic curves. (Homo sapiens) PubMed

 27712.

By testing for THBS2 and another marker, CA19-9, researchers identified blood samples from patients with the disease with 98% specificity and 87% sensitivity. (Homo sapiens) PubMed

 27713.

The major findings outlined in the current study confirmed the potential of eukaryotic initiation factor 5A2 as a promising prognosis predictor and therapeutic target for cervical carcinoma treatment. (Homo sapiens) PubMed

 27714.

The high expression of the IL-25 and IL-33 receptors on the basophil membrane of patients with severe asthma indicates an overstimulation of basophils by these cytokines in severe asthma. [IL-25 receptor; IL-33 receptor] (Homo sapiens) PubMed

 27715.

miR-19b might represent a crucial modifier of the cardiac electrical activity, and our work establishes miR-19b as a potential candidate for human long QT syndrome (Homo sapiens) PubMed

 27716.

The present study suggested that the tumor suppressor miR30c may be involved in prostate cancer tumorigenesis, possibly via targeting ASF/SF2. [miR30c] (Homo sapiens) PubMed

 27717.

CircRNA circ_0067934 directly suppressed miR-1324, which targeted the 3'-UTR of FZD5 mRNA and subsequently downregulated the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma. [CircRNA circ_0067934] (Homo sapiens) PubMed

 27718.

The present study found that the KLF4 and KLF5 3'-UTR contains one conserved target site of miR-506 and miR-124, and the overexpression of miR-506 and miR-124 inhibited the H2O2-induced upregulation of KLF4 and KLF5 in HCMs. (Homo sapiens) PubMed

 27719.

It was concluded that urinary trypsin inhibitor may protect mitochondrial functions by promoting mitochondrial fusion and limiting mitochondrial fission, thus reducing the apoptosis of lipopolysaccharideinduced HK2 cells. [urinary trypsin inhibitor] (Homo sapiens) PubMed

 27720.

The mechanism study revealed that ASLNC02525, as an RNA sponge, broke the negative regulation of twist1 by hsa-miRNA-489-3p, and once ASLNC02525 was silenced, the highly expressed hsa-miRNA489-3p regained its regulation on twist1 and inhibited the proliferation and invasion. (Homo sapiens) PubMed

 27721.

miR-942 and miR-133 were confirmed as being differentially expressed in tumors of responding and non-responding patients with metastatic renal cell carcinoma treated with sunitinib (Homo sapiens) PubMed

 27722.

These findings demonstrate a critical role of miR-199a-3p/DDR1 pathway in ovarian cancer development [miR-199a] (Homo sapiens) PubMed

 27723.

these results provide insights into a novel coordinated interplay among three important molecular players in lipid homeostasis - circulating miR-24, miR-223 and PCSK9 - whose regulation is affected by HCV infection and treatment-based viral cure. (Homo sapiens) PubMed

 27724.

The authors describe two crystal structures, at 1.45 A and 1.65 A resolution, of CcmP from Synechococcus elongatus PCC7942 (SeCcmP). The central pore of CcmP is open or closed at its ends, depending on the conformation of two conserved residues, Glu69 and Arg70.[CcmP] (Homo sapiens) PubMed

 27725.

DQ786243 may have potential as a novel biomarker for the diagnosis of gastric cancer.[lncRNADQ786243] (Homo sapiens) PubMed

 27726.

Long Noncoding RNA AK021443 significantly controlled HepG2 and Bel-7402 cell proliferation, colony formation, invasion, and migration by repressing epithelial-mesenchymal transition, which might provide a potential therapeutic target for Hepatocellular carcinoma diagnosis. [LncRNA AK021443, Human] (Homo sapiens) PubMed

 27727.

our study identified miR-199a-3p and miR-214-3p as independent prognostic biomarkers for the prediction of OS in MIBC patients after RC. (Homo sapiens) PubMed

 27728.

silica-stimulated macrophages secreted TGF-beta1 to induce lncRNA-ATB in epithelia cells, promoting epithelial-mesenchymal transition by binding with miR-200c and releasing ZEB1 [lncRNA-ATB] (Homo sapiens) PubMed

 27729.

Circulating mir-125b-5p was positively correlated with HbA1c in Type 1 diabetics. (Homo sapiens) PubMed

 27730.

miR-7-5p decreased the expression level of TFF3, and inhibited LS174T cell proliferation and migration, accompanied by decreased expression of PI3K and p-Akt. (Homo sapiens) PubMed

 27731.

lncRNA-ATB was upregulated in kidney transplant patients with acute rejection. lncRNA-ATB could influence the kidney cell phenotypes and impact the nephrotoxicity of immunosuppressive drug. (Homo sapiens) PubMed

 27732.

sequestosome1; p62 review of observations on the function of P62 relevant to autophagy and mitophagy in neurodegenerative diseases (Homo sapiens) PubMed

 27733.

These results indicate that Uc.160+, a transcribed ultraconserved region, could possibly have a tumor suppressive role in gastric cancer (Homo sapiens) PubMed

 27734.

The miR-3656/RHOF/EMT axis is an important factor involved in regulating gemcitabine-resistance in pancreatic cancer. (Homo sapiens) PubMed

 27735.

lnc-DILC is a novel colorectal cancer (CRC) suppressor and may prove to be an inhibitor of CRC progression by inactivating IL-6/STAT3 signaling. [lnc-DILC] (Homo sapiens) PubMed

 27736.

These findings demonstrated that FAM196B may promote gastric cancer cell proliferation by activating AKT signaling pathway. [FAM196B] (Homo sapiens) PubMed

 27737.

data strongly suggest that ZNF488 acts as an oncogene, promoting invasion and tumorigenesis by activating the Wnt/beta-catenin pathway to induce epithelial mesenchymal transition in nasopharyngeal carcinoma [ZNF488] (Homo sapiens) PubMed

 27738.

miR-3607 contributes to lung cancer cell proliferation by inhibiting APC.[miR3607] (Homo sapiens) PubMed

 27739.

High-levels of PIVKA-II in at-risk patients is an indicator of hepatocellular carcinoma (HCC)development in two-year time. CONCLUSIONS: Our data showed that PIVKA-II effectively increases the detection rate of HCC was a valid complement to AFP and image examination in HCC surveillance (Homo sapiens) PubMed

 27740.

the expression profiles of human umbilical vein endothelial cells (HUVECs) and verifies the role of hsa_circ_0003575 on HUVECs.[has_circ_0003575] (Homo sapiens) PubMed

 27741.

Results show that LncRNA RP11-552M11.4 expression was elevated in epithelial ovarian cancer (EOC) tissues and correlated with higher pathological grade and worse overall survival in EOC patients. LncRNA RP11-552M11.4 promoted SKOV3 cell proliferation, migration and invasion whereas it inhibited apoptosis by down-regulating BRCA2 in EOC. [LncRNA RP11-552M11.4] (Homo sapiens) PubMed

 27742.

the expression of AP003419.16 increased significantly in patients with IPF, while its adjacent gene RPS6KB2 increased simultaneously. Analysis of the expression of AP003419.16 may predict an increased risk of aging-associated IPF. (Homo sapiens) PubMed

 27743.

miR-720 acted as a tumour suppressor in pancreatic cancer by directly targeting CCND1. (Homo sapiens) PubMed

 27744.

The genotype frequency of HNA-3a/3b which will be helpful to estimate the potential risk for forming anti-HNA-3a, was determined.[HNA-3a, HNA-3b] (Homo sapiens) PubMed

 27745.

Further study revealed AP000439.3 can regulate expression of CCND1 through enhancing estrogen receptor induction of CCND1. This finding revealed lncRNAs may serve as important effectors of ER in regulation of gene expression and cell phenotype in breast cancer (Homo sapiens) PubMed

 27746.

Data demonstrated an upregulation of miR-1274a in clear cell renal cell carcinoma (ccRCC) clinical specimens and cell lines. Suppression of miR-1274a significantly inhibited cancer cell proliferation through apoptosis, suggesting that miR-1274a functions as an oncogenic miRNA in ccRCC cells. [miR-1274a] (Homo sapiens) PubMed

 27747.

this study reveals a protective role for miR-706 by blocking the oxidative stress-induced activation of PKCalpha/TAOK1. Our results further identify a major implication for miR-706 in preventing hepatic fibrogenesis and suggest that miR-706 may be a suitable molecular target for anti-fibrosis therapy. (Homo sapiens) PubMed

 27748.

Secretory miRNAs are present in GCF and secretory miRNA-29 family expression profiles increase during the tooth movement in humans. Secretory miRNA-29 in GCF could serve as potential biomarkers for periodontal remodeling. (Homo sapiens) PubMed

 27749.

the oncogenic potential of LncEGFR, is mediated via positive regulation of EGFR in human tongue cancer. [Lnc-EGFR] (Homo sapiens) PubMed

 27750.

[NDF] NDF, a nucleosome-destabilizing factor that facilitates Pol II transcription in chromatin (Homo sapiens) PubMed

 27751.

miR103 was upregulated in CRC. Overexpression of miR103 promoted CRC cell proliferation and migration in vitro, whereas downregulation of miR103 inhibited cell proliferation and migration. ZO1 was identified as a direct target of miR103, revealing its expression to be inversely correlated with miR103 expression in CRC samples. (Homo sapiens) PubMed

 27752.

As the miR181c expression level was greatly decreased at the early stage of glioma, and continued to decline by >1,000-fold with the development of glioma (to Grade IV), miR181c maybe a crucial factor involved in the glioma cell transformation and glioma progression. (Homo sapiens) PubMed

 27753.

lincRNAp21 is a major mediator of oxLDLinduced apoptosis and expression of LOX1 in human vascular endothelial cells, and acts via activation of PKCdelta. [lincRNA p21, OxLDL] (Homo sapiens) PubMed

 27754.

We suggest that lncRNA-TRPM2-AS participates in the resistance of NSCLC cells to cisplatin, which may provide a new therapeutic target of NSCLC. (Homo sapiens) PubMed

 27755.

lncRNA625 could functionally inhibit PC3 cells proliferation and promote cells apoptosis. (Homo sapiens) PubMed

 27756.

14-3-3beta silencing was able to suppress proliferation and migration of osteosarcoma cells, possibly through the inactivation of the canonical Wnt/beta-catenin signaling pathway. (Homo sapiens) PubMed

 27757.

NEAT1 acts a sponge of miR-101 in cervical cancer, and NEAT1 level is upregulated in cervical cancer, where it correlates with unfavorable clinicopathologic factors and poor prognosis. NEAT1 plays a crucial role in cervical cancer cell proliferation, apoptosis, migration and invasion targeting miR-101. (Homo sapiens) PubMed

 27758.

Oxidized low density lipoprotein facilitates tumor necrosis factoralpha mediated chondrocyte death via its interaction with LOX1, and autophagy is involved in the mechanisms. (Homo sapiens) PubMed

 27759.

the miR-181a was down-regulated in NSCLC and miR-181a inhibited the cell proliferation by regulating CDK1 expression. (Homo sapiens) PubMed

 27760.

Data found that both miR-7a and miR-24-3p had a significantly higher copy number in non-malignant lung tissues (NMLTs) samples compared to lung adenocarcinoma (AC) tissues and that they both modulate the SOX18 transcript in AC cells. [miR-7a] (Homo sapiens) PubMed

 27761.

Results show that S. aureus RNase J1 encoded by rnjA, is a manganese dependent homodimeric enzyme with strong 5' to 3' exo-ribonuclease as well as endo-ribonuclease activity. In addition, SauJ1 can efficiently degrade 5' triphosphorylated RNA. [rnjA] (Homo sapiens) PubMed

 27762.

findings advance our understanding of the role of long non-coding RNA XLOC_010235 as an oncogene in HCC, which may help in the development of new therapeutics (Homo sapiens) PubMed

 27763.

The model predicts that the most likely last step in turning the ancestral primate HAR1 into the human HAR1 was exactly the substitution that distinguishes the modern human HAR1 sequence from that of Denisovan, an archaic human.[HAR1] (Homo sapiens) PubMed

 27764.

a decreased level of miR-223-3p in HCC was markedly associated with its diagnostic value, possibly by targeting potential genes in different biological pathways. Therefore, the present study revealed that miR-223-3p merits attention as a significant biomarker in the diagnostic setting and tumorigenesis of HCC. (Homo sapiens) PubMed

 27765.

(MiR-9-5p) MiR-9-5p promotes the proliferation, metastasis and invasion of non-small cell lung cancer cells by down-regulating TGFBR2 expression. (Homo sapiens) PubMed

 27766.

miR-105/93-3p activates Wnt/beta-catenin signaling by downregulating SFRP1 and thereby promotes stemness, chemoresistance, and metastasis in TNBC cells. (Homo sapiens) PubMed

 27767.

miR-194 and miR-b2122 to be significantly down-regulated in sALS patients, and were predicted to regulate TARDBP, FUS/TLS and RGNEF expression.[miR b2122] (Homo sapiens) PubMed

 27768.

BCSG1 siRNA delivered by lentiviral vector was able to significantly reduce BCSG1 expression, suppress cell migration and proliferation.[BCSG1] (Homo sapiens) PubMed

 27769.

Downregulated Long noncoding RNAATB expression suppressed cellular proliferation, invasion and migration of Gastric Cancer cells. [Long noncoding RNAATB] (Homo sapiens) PubMed

 27770.

L1RE1 in combination with either RARB or RASSF1 could function as biomarkers for separating lung cancer and non-cancerous tissue[l1re1] (Homo sapiens) PubMed

 27771.

PI5P4Kgamma positively regulates the DTX1-mediated Notch pathway by promoting receptor recycling [PI5P4Kgamma] (Homo sapiens) PubMed

 27772.

BG981369 and SOX4 are potentially effective therapeutic targets for gastric cancer.[BG981369] (Homo sapiens) PubMed

 27773.

This study shows that LncRNA MT1JP Suppresses Gastric Cancer Cell Proliferation and Migration Through MT1JP/MiR-214-3p/RUNX3 Axis. [LncRNA MT1JP] (Homo sapiens) PubMed

 27774.

miR-218 inhibits human lung adenocarcinoma cell migration and invasion via the suppression of Ecop and Robo1 expression (Homo sapiens) PubMed

 27775.

CASC2a was down-regulated in patients with urothelial carcinoma of the bladder.[CASC2a] (Homo sapiens) PubMed

 27776.

MRCCAT1 is a critical lncRNA that promotes clear cell renal cell carcinoma metastasis via inhibiting NPR3 and activating p38-MAPK signaling.MRCCAT1 is upregulated in metastatic clear cell renal cell carcinoma tissues.[MRCCAT1] (Homo sapiens) PubMed

 27777.

Linc00152 is a direct target of miR-103a-3p.miR-103a-3p plays a novel role in regulating the malignant behavior of glioma stem cells as a part of Linc00152/miR-103a-3p/FEZF1/CDC25A axis.[miR-103a-3p] (Homo sapiens) PubMed

 27778.

These results suggest that Long Non-Coding RNA AC007271.3, squamous cell carcinoma antigen (SCCA), and tumor-specific growth factor (TSGF), could be novel circulating biomarkers for the determination of Oral Squamous Cell Carcinoma. [Long Non-Coding RNA AC007271.3, SCCA, TSGF] (Homo sapiens) PubMed

 27779.

Serum IL-35 and IL-35 mRNA were significantly down regulated in chronic hepatitis B patients.[IL-35] (Homo sapiens) PubMed

 27780.

downregulation of XLOC_010588 inhibited the invasion and migration of colorectal cancer (CRC)cells by regulating genes associated with EMT. Our findings revealed that XLOC_010588 may be considered as a novel potential diagnostic biomarker in CRC. (Homo sapiens) PubMed

 27781.

findings suggest that rs13230517 polymorphism in the promoter region of RP11-3N2.1might participate in the pathogenesis of colorectal cancer (CRC) and have the potential to be a biomarker for predicting the risk of CRC (RP11-3N2.1). (Homo sapiens) PubMed

 27782.

miR-24 is up-regulated in age-related cataracts. It appears to enhance lens epithelial cell apoptosis and inhibit cell proliferation by directly targeting p53, suggesting that the miR-24-p53 pathway may play a critical role in cataractogenesis. (Homo sapiens) PubMed

 27783.

All these results indicate that lncRNA AB073614 can induce the expression of epithelial-mesenchymal transition (EMT) cell markers and regulate the process of EMT of colorectal cancer cells through regulating the JAK/STAT3 pathway activation[ AB073614 ] (Homo sapiens) PubMed

 27784.

Elevated levels of serum b2-GPI/oxLDL complexes are associated with cerebral infarction in patients with type 2 diabetes mellitus, especially in those with lacunar infarction.[beta2 GPI, OxLDL] (Homo sapiens) PubMed

 27785.

expression of lncRNA AC010761.9 had a positive correlation with the mRNA expression of the potentially associated gene (TRAF4) in gastric adenocarcinoma tissues[AC010761.9] (Homo sapiens) PubMed

 27786.

TGFbeta1 2.5ng/ml induced the alternative splicing of extra domain A fibronectin shown by conventional RT-PCR. (Homo sapiens) PubMed

 27787.

Enforced expression of lncRNA TUBA4B obviously reduced the proliferation of SKOV3 cells[lncRNA TUBA4B] (Homo sapiens) PubMed

 27788.

These findings indicate that HS3ST3B1 is a novel regulator of TGF-beta-mediated EMT and is regulated by miR-218 in NSCLC. (Homo sapiens) PubMed

 27789.

Circ2174 has sequence complementarity to miR149 which can target Oct-2.These data suggest a mechanism whereby circ2174 can act as a sponge to regulate the expression of miR149, and thereby modulate Oct-2 and interleukin-16 signaling pathways in cholangiocarcinoma. (Homo sapiens) PubMed

 27790.

recurrent IGH-DUX4 or ERG-DUX4 fusions, ETV6-RUNX1-like gene-expression profile in B-cell precursor acute lymphoblastic leukaemia, is reported.[ETV6-RUNX1-like] (Homo sapiens) PubMed

 27791.

The novel oncogenic lncRNA AK023391 in gastric cancer exerts its effects through activation of the PI3K/Akt signaling pathway, and may act as a potential biomarker for survival in patients with gastric cancer (AK023391). (Homo sapiens) PubMed

 27792.

lncBRM and YAP1 signalling may serve as biomarkers for diagnosis and potential drug targets for hepatocellular carcinoma.[lncBRM] (Homo sapiens) PubMed

 27793.

serum concentrations of IL-6 and PINP change in liver diseases, and those changes reflect the severity of liver disease.[PINP] (Homo sapiens) PubMed

 27794.

Met117 oxidation caused enhanced flexibility and decreased compactness in oxidized state. PAF binding interaction with oxidized protein was mediated only through hydrophobic interactions.[PAF] (Homo sapiens) PubMed

 27795.

nockdown of either ASMER-1 or ASMER-2 by antisense oligonucleotides in in vitro differentiated human adipocytes revealed that both genes regulated adipogenesis, lipid mobilization and adiponectin secretion.[ASMER-1, ASMER-2] (Homo sapiens) PubMed

 27796.

LncRNA activated by transforming growth factor-beta (ATB) is upregulated in cervical cancer and correlates with cancer development (LncRNA activated by transforming growth factor-beta: ATB) (Homo sapiens) PubMed

 27797.

circNASP contributes to malignant behaviors of osteosarcoma cells by miR-1253/FOXF1 pathway.[circNASP] (Homo sapiens) PubMed

 27798.

we have discovered the novel N-72, and it was crucial for EGF-induced migration by targeting MMP2 in Human amnion mesenchymal stem cells (hAMSCs) (Homo sapiens) PubMed

 27799.

The results of the present study indicate that the expression of miRNA23a may regulate acute myocardial infarction (AMI) through targeting PTEN in patients and in vitro, and PTEN/miRNA23a may therefore be potential targets for the clinical treatment of AMI. [miRNA23a] (Homo sapiens) PubMed

 27800.

These results indicate that long non-coding RNA TCF7 may predict the progression, and promote the growth and metastasis, of colorectal cancer. [ long non-coding RNA TCF7 ] (Homo sapiens) PubMed

 27801.

A total of 2,041 significant the differentially expressed lncRNAs were identified in Lung squamous cell carcinoma (LUSC) samples. RP5-821D11.7 (co-expressed with PCNA), APCDD1L-AS1 (co-expressed with SEMA5A, SEMA6D, ADAMTSL1, ADAMTS6, SLIT3 and TNC) and RP11-277P12.9 (co-expressed with WNT2B) may be important lncRNAs associated with the prognosis of LUSC. [RP5-821D11.7, RP11-277P12.9] (Homo sapiens) PubMed

 27802.

hsa_circ_0014717 acts as a potential tumor suppressor that inhibits colorectal cancer growth, partly at least, through upregulating p16 expression.[hsa_circ_0014717] (Homo sapiens) PubMed

 27803.

These findings provide evidence for LINC01314 as a potential biomarker and anti-cancer therapeutic target in patients with hepatoblastoma.[LINC01314] (Homo sapiens) PubMed

 27804.

hsa_circ_0000673 promoted hepatocellular carcinoma malignant behaviors via regulating miR-767-3p/SET pathway. (Homo sapiens) PubMed

 27805.

Data suggest that serum levels of MIRN1181 and MIRN4314 are significantly up-regulated in women with ovarian cancer stages I-IV as compared to normal subjects. [PILOT PROJECT] (MIR4314/MIRN4314, microRNA 4314) (Homo sapiens) PubMed

 27806.

snoU2_19 plays a pathological role in the development and progression of hepatocellular carcinoma.[snoU2_19] (Homo sapiens) PubMed

 27807.

human retinal endothelial cells expressed ICR, and observed induction of expression by tumor necrosis factor-alpha.[ICR] (Homo sapiens) PubMed

 27808.

Our results revealed that exosomal miR23b has potential as minimally invasive predictive biomarker for the recurrence and prognosis of gastric cancer in patients at all stages. (Homo sapiens) PubMed

 27809.

(MOTS-c peptide) Lower circulating endogenous MOTS-c levels in human subjects are associated with impaired coronary endothelial function. (Homo sapiens) PubMed

 27810.

the expression of hsa_circRNA0054633 has a protective effect against high glucoseinduced endothelial cell dysfunction by targeting ROBO1 and HO1.[hsa_circRNA0054633] (Homo sapiens) PubMed

 27811.

IDO decreased glycolysis and glutaminolysis by activating GCN2K, resulting in activation of AMPactivated protein kinase.[GCN2K] (Homo sapiens) PubMed

 27812.

miR-181a-5p was upregulated in RCC tissues and cell lines, and that miR-181a-5p was associated with cell migration, proliferation and apoptosis in RCC. (Homo sapiens) PubMed

 27813.

The results of the tumorigenicity assay revealed that circCDK13 overexpression significantly inhibited liver cancer progression in nude mice. On the whole, the findings of this study indicate that circCDK13 is a novel circular RNA that suppresses liver cancer progression, and that these suppressive effects are possibly mediated via the JAK/STAT and PI3K/AKT signaling pathways. (Homo sapiens) PubMed

 27814.

C2dat1 suppression reduced osteosarcoma cell viability, migration, and invasion and enhanced cell apoptosis. This process was mediated by the upregulation of miR-34a-5p (Homo sapiens) PubMed

 27815.

the hsa_circ_0071589/miR-600/EZH2 axis may play critical regulatory roles in the pathogenesis of colorectal cancer.[hsa_circ_0071589] (Homo sapiens) PubMed

 27816.

(presepsin) Compared with the pre-operative value, presepsin was significantly higher immediately after surgery and returned to pre-operative levels one week after surgery. (Homo sapiens) PubMed

 27817.

mir-548a the expression of miR-548a-3p is upregulated in IL-22 mediated keratinocyte proliferative disorder like psoriasis (Homo sapiens) PubMed

 27818.

The PBII gene of the human salivary proline-rich protein P-B produces another protein, Q504X8, with an opiorphin homolog, QRGPR. (Homo sapiens) PubMed

 27819.

circRNA_102231 could act as a potential biomarker and therapeutic target for lung cancer patients.[circRNA_102331] (Homo sapiens) PubMed

 27820.

oncogene miR-566 is a potential biomarker not only for diagnosis but also for prognosis for Renal cell carcinoma.[miR566] (Homo sapiens) PubMed

 27821.

lncRNA RP4 plays an important role in the progression of human colorectal cancer by regulating the expression of SH3GLB1 through miR-7-5p sponge activity. (Homo sapiens) PubMed

 27822.

hsa_circ_0007534 serves as an oncogene in glioma via promoting ZIC5 expression by repressing miR-761 availability.[Circ_0007534] (Homo sapiens) PubMed

 27823.

sing in vitro and in vivo models, we found that canonical NLRP3 and non-canonical caspase-11 inflammasomes were activated in bone-associated MSCs (BA-MSCs) to promote the inflammatory response (Homo sapiens) PubMed

 27824.

function of circRNA-MYLK on prostate cancer cells was affected through targeting miR-29a.[CircRNA-MYLK] (Homo sapiens) PubMed

 27825.

circC3P1 acts as a tumor suppressor via enhancing PCK1 expression by sponging miR-4641 in hepatocellular carcinoma.[circC3P1] (Homo sapiens) PubMed

 27826.

Study demonstrated that miR-5095 bound to the 3'UTR of MYCN and downregulated its expression in cholangiocarcinoma (CCA). LINC01296 was predicted to interact with miR-5095 by computational algorithms. Its expression was negatively correlated with LINC01296 in CCA. [miR-5095] (Homo sapiens) PubMed

 27827.

long noncoding RNA PlncRNA-1 may exert tumor-promoting role in the development and progression of glioma through modulation of Notch signal pathway.[PlncRNA-1] (Homo sapiens) PubMed

 27828.

Clinical detection of serum and urine BLCA-1 protein levels showed a high level of sensitivity and specificity in diagnosing bladder cancer.[BLCA-1] (Homo sapiens) PubMed

 27829.

Expression of lncRNA, LL22NC03-N64E9.1, promoted proliferation of lung cancer cells in vitro.[LL22NC03-N64E9.1] (Homo sapiens) PubMed

 27830.

MiR-199a-5p may mediate cleft lip with or without cleft palate by regulating key target gene TGFA [miR-199a-5p]. (Homo sapiens) PubMed

 27831.

observations collectively demonstrate that AF119895 modulates the repression of NXF3 by binding to miR-6508-3p[AF119895] (Homo sapiens) PubMed

 27832.

The experimental data corroborated the inhibitory function of miR-513a-5p on progesterone receptor expression in breast cancer confirming that progesterone receptor is a target of miR-513a-5p (Homo sapiens) PubMed

 27833.

highly expressed AX800134 acts as an oncogenic factor promoting tumor cell growth and invasion in HBV-associated HCC, and the upregulation of AX800134 is related with the viral product HBx and chronic inflammation (Homo sapiens) PubMed

 27834.

RP11543N12.1 and miR3243p may be potential biomarkers and therapeutic targets for Alzheimer's disease.[RP11-543N12.1] (Homo sapiens) PubMed

 27835.

WISP1-AS1 is a novel lncRNA with modulatory transcriptional function and the potential to alter the cellular phenotype in situations of stress or oncogenic transformation. [WISP1-AS1 long noncoding RNA] (Homo sapiens) PubMed

 27836.

This meta-analysis suggests that elevated PIVKA-II is a predictor of unfavorable overall survival and recurrence-free survival in hepatocellular carcinoma patients receiving curative ablation. More rigorous studies are warranted to confirm the clinical utility of PIVKA-II in determining hepatocellular carcinoma prognosis (Homo sapiens) PubMed

 27837.

Bioinformatics and luciferase reporter assays confirmed that circRNA_0084043 directly binds to miR-153-3p, and Snail is directly targeted by miR-153-3p. [miR-153-3p] (Homo sapiens) PubMed

 27838.

the findings demonstrated that lncRNA-ATB was an oncogene that promoted cell proliferation, migration, and invasion by regulating miR-126 (lncRNA-ATB). (Homo sapiens) PubMed

 27839.

miR-519d-3p overexpression suppressed proliferation, inhibited the cell cycle, and promoted apoptosis of HeLa cells by targeting HIF-2alpha under hypoxic conditions (miR-519d-3p). (Homo sapiens) PubMed

 27840.

Results suggest that lncRNA NONHSAT129183 plays a critical role in the regulation of papillary thyroid cancer cell proliferation, migration, and invasion (lncRNA NONHSAT129183). (Homo sapiens) PubMed

 27841.

hsa_circ_0001649 might be a potentially useful prognostic biomarker and therapeutic target for retinoblastoma. [hsa_circ_0001649] (Homo sapiens) PubMed

 27842.

Results show that Lnc-PCDH9-13:1 were overexpressed in hepatocellular carcinoma (HCC) tissue, plasma and saliva. Its tissue levels correlated significantly with those in plasma and saliva. These finding suggest that salivary lnc-PCDH9-13:1 is a novel hypersensitive and specific biomarker in diagnosis of early HCC. [Lnc-PCDH9-13:1] (Homo sapiens) PubMed

 27843.

Long Noncoding RNA CAT104 might function as an oncogenic factor in gastric carcinoma cells via regulating the expression of miR-381 and ZEB1 (Long Noncoding RNA CAT104). (Homo sapiens) PubMed

 27844.

These results suggest that miR-24-3p functions as a tumor suppressor and the miR-24-3p/p130Cas axis is a novel factor of cancer progression by regulating cell migration and invasion. (Homo sapiens) PubMed

 27845.

Long noncoding-EGFR stimulates Tregulatory cell differentiation, suppresses cytotoxic t lymphocyte activity and promotes hepatocellular carcinoma growth in an EGFR-dependent manner. (Homo sapiens) PubMed

 27846.

Circ-CFH promotes glioma progression by sponging miR-149 and regulating the AKT1 signaling pathway.[Circ-CFH] (Homo sapiens) PubMed

 27847.

Study indicated that lncRNAATB functions as a ceRNA to promote MM proliferation and invasion by enhancing Yes associated protein 1 expression by competitively sponging microRNA miR5905p (lncRNA-ATB). (Homo sapiens) PubMed

 27848.

Our findings suggest that miR-23 plays a crucial role in controlling VSMCs proliferation and apoptosis by targeting BCL2L11[mir23] (Homo sapiens) PubMed

 27849.

we demonstrated that HS3ST3B enhances the proliferation and survival of breast cancer MDA-MB-231 cells, via a mechanism that is dependent on Nrp1. (Homo sapiens) PubMed

 27850.

These findings suggest that miR-26 and miR-125b may be associated with the progression and metastasis of HNSCC.[MIR26] (Homo sapiens) PubMed

 27851.

miR-103 programs endothelial cells toward a maladapted phenotype through targeting of lncWDR59, which may promote atherosclerosis.[lncWDR59] (Homo sapiens) PubMed

 27852.

Suggest role for LncRNA-NR_033515 in promoting proliferation, fibrogenesis and epithelial-to-mesenchymal transition by targeting miR-743b-5p in diabetic nephropathy. (Homo sapiens) PubMed

 27853.

miR-218-5p was downregulated in invasion front cells and negatively regulates oral squamous cell carcinoma invasiveness by targeting the CD44-ROCK pathway. (Homo sapiens) PubMed

 27854.

lncGNAT11 is downregulated in gastric cancer infected with H. pylori and lncGNAT11 overexpression inhibited gastric cancer growth through the Wnt/betacatenin signaling pathway.[lncGNAT1-1] (Homo sapiens) PubMed

 27855.

Long non-coding RNA FTH1P3 regulates invasive/metastatic potential of esophageal squamous cell carcinoma via SP1/NF-kB pathway. (Homo sapiens) PubMed

 27856.

Functional assays to reveal the targets of n-miR-G665 showed that polycomb protein Suz12 is regulated by n-miR-G665, which in turn regulates the expression of n-miR-G665 through feedback loop mechanism.[n-miR-G665] (Homo sapiens) PubMed

 27857.

Mitochondrial permeability transition pore contributes to mitochondrial failure in Alzheimer's disease fibroblasts.[mitochondrial permeability transition pore] (Homo sapiens) PubMed

 27858.

the present study suggests that dermcidin is a novel binding protein of lncRNA STCAT3, which serves an important role in the progress and clinical outcome of gastric cancer (Homo sapiens) PubMed

 27859.

these results indicate that XLOC_000647 functions as a novel tumor suppressor of lncRNA and acts as an important regulator of NLRP3, inhibiting cell proliferation, invasion, and EMT in PC. (Homo sapiens) PubMed

 27860.

lncRNA RP185F18.6 and DeltaNp63 may be considered unfavorable biomarkers, whereas GSDMD may be a favorable biomarker in CRC; these markers may prove valuable in the future diagnosis and prognosis of CRC. (Homo sapiens) PubMed

 27861.

hsa_circ_0007534 may be a rational predictive marker and therapeutic target for osteosarcoma.[has_circ_0007534] (Homo sapiens) PubMed

 27862.

Long noncoding RNA lncAPC promotes liver tumor initiating cells self-renewal through EZH2-dependent APC transcriptional inhibition. [Long noncoding RNA lncAPC ] (Homo sapiens) PubMed

 27863.

There were no statistically significant differences inbronchoalveolar lavage fluid pepsin levels among patients with the different chronic fibrosing interstitial lung diseases.[Pepsin] (Homo sapiens) PubMed

 27864.

RP11-714G18.1 may play an athero-protective role by inhibiting vascular cell migration via RP11-714G18.1/LRP2BP/MMP1 signaling pathway.[LncRNA-RP11-714G18.1] (Homo sapiens) PubMed

 27865.

cardiac conduction regulatory RNA (CCRR) is identified as an antiarrhythmic long noncoding RNA.[lncRNA CCRR] (Homo sapiens) PubMed

 27866.

The physiological variation in plasma presepsin levels was observed during the early neonatal period.[Presepsin] (Homo sapiens) PubMed

 27867.

Taken together, these observations suggest that Long non-coding RNA AGER-1 has an inhibitory effect on lung cancer development via AGER, which may serve as a target for lung cancer treatment. [Long non-coding RNA AGER-1] (Homo sapiens) PubMed

 27868.

The results of this study provide a promising experimental basis for the treatment of gastric cancer through interventional targeting of long non-coding RNA (lncRNA) ENST00000434223. (Homo sapiens) PubMed

 27869.

High baseline serum CA19-9 may predict a good prognosis in patients with advanced Urothelial Carcinoma (Homo sapiens) PubMed

 27870.

KCNQ1OT1 was significantly up-regulated in oxaliplatin-resistant hepatocellular carcinoma cells. KCNQ1OT1 modulated oxaliplatin resistance in hepatocellular carcinoma through miR-7-5p/ ABCC1 axis. [miR-7-5p] (Homo sapiens) PubMed

 27871.

these data suggest that miR-103, miR-195, and miR-15b post-transcriptionally downregulated the expression of SALL4 and suppressed glioma cell growth, migration, and invasion, and increased cell apoptosis. (Homo sapiens) PubMed

 27872.

These results provide evidence for a novel regulatory function of tumor-derived exosomal lncRNA TUC339 in environmental macrophages.[lncRNA TUC339] (Homo sapiens) PubMed

 27873.

lncRNA kcna3 exerts a tumor-inhibit role in colorectal cancer progression through down-regulating YAP1 expression.[lncrna Kcna3] (Homo sapiens) PubMed

 27874.

A transient induction of the human UNC45-GC, but not UNC45-SM, could rescue the defective endocytosis in these she4Delta cells at 39 degrees C, irrespective of whether they possessed Hsp90alpha or Hsp90beta.[UNC45-SM] (Homo sapiens) PubMed

 27875.

High CA19-9 levels, CD44 H-scores and poor differentiation are independent predictors for ER in PDAC patients undergoing radical resection. Therefore, the determination of CD44 expression might help in identifying patients at a high risk of ER for more aggressive treatment after radical surgery. (Homo sapiens) PubMed

 27876.

Our recommendation is for addition of PIVKA-II to the routine panel of hepatocellular carcinoma tumour markers. (Homo sapiens) PubMed

 27877.

The results demonstrate, that MSCA-1+ cells isolated from cranial periosteal cell (CPC) fractions represent a subpopulation with a higher osteogenic potential. In contrast, the study found a lower osteogenic potential in CD146+ CPCs. In conclusion, only MSCA-1, but not CD146, is a suitable marker for the isolation of osteoprogenitors from CPCs. [MSCA-1] (Homo sapiens) PubMed

 27878.

Long Non-Coding RNA XLOC_006753 was highly expressed in Gastric Cancer patients and multidrug resistant Gastric Cancer cell lines (SGC-7901/5-FU and SGC-7901/DDP cell lines), and its high expression was positively associated with metastasis, tumor size, and poor survival. [Long Non-Coding RNA XLOC_006753] (Homo sapiens) PubMed

 27879.

downregulation of lncRNA NEAT1_2 radiosensitizes hepatocellular carcinoma cells through regulation of miR-101-3p/WEE1 axis.[lncRNA NEAT1_2] (Homo sapiens) PubMed

 27880.

our study indicates that manipulating Artemis can enhance colorectal cancer cell sensitivity to DNA-damaging agents. Therefore, Artemis can serve as a therapeutic target in rectal cancer therapy (Homo sapiens) PubMed

 27881.

that patients with AMI following radical surgery for GC had higher miR-133a expression compared with patients without AMI. In addition, the results indicated that miR-133a could regulate the endothelial injury process following AMI though the modulation of endothelial cells via targeting Bcl2l1. (Homo sapiens) PubMed

 27882.

our research verified that suppression of CAT104 exerted significant inhibitory effects on osteosarcoma cell proliferation, migration, and invasion by regulating the expression of miR-381 and downstream ZEB1, as well as JNK and Wnt/b-catenin pathways. (Homo sapiens) PubMed

 27883.

(IL-12p70) Days with migraine and IL-12p70 plasma levels were significantly reduced in an exercise-trained group of women with migraine. (Homo sapiens) PubMed

 27884.

this is the first study to verify the dysregulated expression of lncRNAn346372 in bladder cancer; an association of this lncRNA with overall survival of bladder cancer patients was also uncovered in the present study, suggesting that lncRNAn346372 may contribute to the initiation and/or progression of bladder cancer with potential applications in the clinic. (Homo sapiens) PubMed

 27885.

Expression of HMB45, MelanA and SOX10 is evident but exceedingly rare in non-small cell lung cancer cases (Homo sapiens) PubMed

 27886.

ENST457720 knockdown inhibited Non-small cell lung cancer (NSCLC)invasion and reversed the epithelial-to-mesenchymal transition. ENST457720 promoted NSCLC proliferation and invasion, which may be a novel potential therapeutic target for NSCLC. (Homo sapiens) PubMed

 27887.

The long non-coding RNA, RUNX1 overlapping RNA (RUNXOR), is significantly associated with the immunosuppression induced by myeloid-derived suppressor cells in lung cancer patients (Homo sapiens) PubMed

 27888.

our results suggest that manipulating p13 expression may be a promising avenue for therapeutic intervention in Parkinson's disease (Homo sapiens) PubMed

 27889.

TAG-72 is thought to be the factors involved in the progression of colorectal cancers and may be considered as one of the potential therapeutic target (Homo sapiens) PubMed

 27890.

Circ-4099 may play a role in a protective mechanism and be part of a compensatory response that maintains the synthesis and secretion of the extracellular matrix in NP cells and might be a protective factor in IVD degeneration as well as restore NP cell function. (Homo sapiens) PubMed

 27891.

These results provide evidence for a novel cell cycle regulatory network in glioma comprising the Long non-coding PLAC2 along with STAT1 and RPL36. (Homo sapiens) PubMed

 27892.

our results found that plasma lncRNA CASC2 expression is lower in PTC and associated with lymph node metastasis. In vitro, we demonstrated that overexpression of lncRNA CASC2 expression suppressed cell proliferation and invasion ability. (Homo sapiens) PubMed

 27893.

we identified that via targeting STMN1, PC cell proliferation and invasion were suppressed by miR-101. (Homo sapiens) PubMed

 27894.

circ_0001649 was identified as the sponge of miR-331-3p and miR-338-5p. Moreover, the biological functions of circ_0001649 is partly dependent on its regulation on miR-331-3p and miR-338-5p; circ_0001649/miR-331-3p/miR-338-5p regulatory signaling might be a potential target for NSCLC therapy [Circular RNA circ_0001649] (Homo sapiens) PubMed

 27895.

miR-3687 expression negatively impacts the prognosis of patients with ESCC [mirR3687] (Homo sapiens) PubMed

 27896.

Listeria monocytogenes secretion of c-di-AMP inhibits RECON ( Akr1c13) activity, drives augmented NF-kappaB activation and nitric oxide production, and ultimately enhances intercellular spread.[RECON/Akr1c13] (Homo sapiens) PubMed

 27897.

Study identified PILAR1 as differentially expressed as well as prognostic LncRNA in lung Adenocarcinoma (LUAD). The PILAR1 expression is associated with a high mutation rate and with the high KEAP1 mutation. Knockdown studies showed that PILAR1 is an essential LncRNA for the growth of LUAD cells. [LncRNA PILAR1] (Homo sapiens) PubMed

 27898.

we found three common lncRNAs across the four subtype-related ceRNA networks, NEAT1, OPI5-AS1 and AC008124.1, which played specific roles in each subtype through competing with diverse mRNAs. (Homo sapiens) PubMed

 27899.

circ_0025039 promotes cell growth, invasion and glucose metabolism in malignant melanoma by sponging miR-198 and regulating CDK4.[Has_circ_0025039] (Homo sapiens) PubMed

 27900.

PTAR was significantly up-regulated in the mesenchymal subtype of ovarian cancer (OvCa) compared with the epithelial subtype. PTAR expression was positively correlated with the expression level of ZEB1 in the mesenchymal OvCa samples. Further analysis showed that enhanced expression of PTAR promoted EMT and metastasis through the regulation of miR-101. Its knockdown reduced tumorigenicity and metastasis. [LncRNA PTAR] (Homo sapiens) PubMed

 27901.

Results show that the ALB1 enhancer DNA contains local flexible regions, as compared to the Widom 601 DNA but associates less strongly with the histones in the nucleosome. (Homo sapiens) PubMed

 27902.

upregulated plasma circRNA_002453 level in Lupus nephritis (LN) patients is associated with the severity of renal involvement and may also serve as a potential biomarker for LN patient diagnosis.[circRNA_002453] (Homo sapiens) PubMed

 27903.

circular RNA 100290 has a role in promoting colorectal cancer progression through miR-516b-induced downregulation of FZD4 expression and Wnt/beta-catenin signaling [circRNA_100290] (Homo sapiens) PubMed

 27904.

LncRNA17A regulates autophagy and apoptosis of neuronal cell line as an in vitro model for Alzheimer's disease. [LncRNA17A] (Homo sapiens) PubMed

 27905.

MiR-514 is of clinically significance in ovarian cancer by attenuating proliferation of ovarian cancer cells and decreasing chemoresistance of cisplatin by targeting ATP binding cassette subfamily. (Homo sapiens) PubMed

 27906.

our study identified miR-199a as a tumor suppressor in CRC cells both in vivo and in vitro. MicroRNA-199a-5p had proved to be suppressed in human CRCs and the reintroduction of it could be a potential method of suppressing the proliferation and progression of CRCs. (Homo sapiens) PubMed

 27907.

Over-expression of miR-199 in gastric carcinoma is associated with the decreased ability of proliferation and migration of gastric carcinoma cells by targeting the 3' untranslated region of TBL1XR1. [miRNA199] (Homo sapiens) PubMed

 27908.

our findings suggest that eRNA lnc-SLC4A1-1 recruits NF-kappaB and binds to the prompter of CXCL8, which leads to upregulation of CXCL8. Increased CXCL8 exacerbates inflammatory reaction by inducing TNF-alpha and IL-1beta and affects trophoblast function, which may impact the immune response and eventually lead to URPL. (Homo sapiens) PubMed

 27909.

Overexpressed METase promoted cell apoptosis and autophagy via up-regulating the expression of SNHG5 and down-regulating miR-20a in GC [METase] (Homo sapiens) PubMed

 27910.

The expression of MiR-128-3p was significantly increased, while TNFAIP3 was decreased, the levels of IL-6 and IL-17 were also increased in the T cells of rheumatoid arthritis patients. [MiR-128-3p] (Homo sapiens) PubMed

 27911.

This study identified a novel Long non-coding RNA AK096174, which was up-regulated and associated with tumorigenesis, tumor size, metastasis, and poor prognosis in Gastric Cancer. [Long non-coding RNA AK096174] (Homo sapiens) PubMed

 27912.

MiR-128-3p directly targets VEGFC/VEGFR3 to modulate the proliferation of lymphatic endothelial cells through Ca(2+) signaling [MiR-128-3p] (Homo sapiens) PubMed

 27913.

Both HSP20 and phosphorylated HSP20 were downregulated in chorionic plate resistance arteries (CPAs) from women with preeclampsia. Comparison of the vasodilative ability of CPAs from the two groups showed impaired relaxation responses to acetyl choline in preeclamptic vessels. [HSP20] (Homo sapiens) PubMed

 27914.

MVIH and Jun-B have a synergistic effect on the regulation of angiogenesis and cell proliferation. (Homo sapiens) PubMed

 27915.

CXCR4 interacted with PI4KIIIalpha membrane targeting machinery recruiting them to the plasma membrane for PI4P production. PI4KIIIalpha was found tightly linked to the CXCR4 induced prostate cancer cell invasion. PI4KIIIalpha expression increased in metastatic tumors vs. the primary. PI4KIIIalpha plays a role in GPCR signaling. PI4KIIIalpha. (Homo sapiens) PubMed

 27916.

this study identified a new miRNA named miR7167 expressed in Human Rheumatoid Arthritis [miR-7167] (Homo sapiens) PubMed

 27917.

Progerin overexpression increased levels of SUN1, which couples the nucleus to microtubules through nesprin-2G and dynein, and microtubule association with the nucleus. Reducing microtubule-nuclear connections through SUN1 depletion or dynein inhibition rescued the polarity defects. (Homo sapiens) PubMed

 27918.

although HuR stabilizes ARE-containing RNAs, we found that RRM3 counteracts this effect, as shown in a cell-based ARE reporter assay and by qPCR with native HuR mRNA targets containing multiple AUUUA motifs, possibly by competing with RRM12. (Homo sapiens) PubMed

 27919.

DMF5 is a T-cell receptor that can productively engage two very different classes of antigens [DMF5] (Homo sapiens) PubMed

 27920.

Long non-coding RNA OGFRP1 contributed to progression of non-small cell lung cancer at least partly through upregulating LYPD3 expression by sponging miR-124-3p (Long non-coding RNA OGFRP1). (Homo sapiens) PubMed

 27921.

This study provides first insights into the biosynthesis, structure, biochemistry and complex processing of the proteins encoded by hNOT/ALG3, the human counterpart of the Drosophila Neighbour of TID (NOT) and the yeast asparagine linked glycosylation 3 gene (ALG3), which encodes a mannosyltransferase (Homo sapiens) PubMed

 27922.

CircRNA_104670 is highly expressed in the nucleus pulposus (NP) tissues of intervertebral disc degeneration and acts as a ceRNA during NP degradation.[CircularRNA_104670] (Homo sapiens) PubMed

 27923.

ZEB1-AS1/miR-409-3p/ZEB1 constitutes a positive feedback loop to promote the tumorigenesis of non-small cell lung cancer.[ZEB1-AS1] (Homo sapiens) PubMed

 27924.

plasma lncRNA snaR and GAB2 were positively correlated in ovarian carcinoma patients but not in healthy controls; lncRNA snaR overexpression promoted cancer cell proliferation and upregulated GAB2 expression [lncRNA snaR] (Homo sapiens) PubMed

 27925.

circDENND2A is required for the hypoxia-induced malignancy of glioma cells and functions by sponging miR-625-5p.[circDENND2A] (Homo sapiens) PubMed

 27926.

Study found a novel anticarcinogenetic LncRNA AC016405.3, that was downregulated in glioblastoma. Functionally, AC016405.3 suppressed proliferation and metastasis of glioblastoma cells. Mechanically, AC016405.3 suppressed TET2-mediated proliferation and metastasis by acting as a competing endogenous RNA of microRNA-19a. [AC016405.3] (Homo sapiens) PubMed

 27927.

the present study identifies the crucial regulation of hsa_circ_100290 in acute myeloid leukemia cell proliferation and apoptosis via targeting the miR-203/Rab10 axis.[hsa_circ_100290] (Homo sapiens) PubMed

 27928.

This study shed light on the oncogene role of lncRNA GClnc1, a new modulator of p53 signaling, in osteosarcoma. (Homo sapiens) PubMed

 27929.

Long non-coding RNA Gm15290 promotes cell proliferation and invasion in lung cancer through directly interacting with and suppressing the tumor suppressor miR-615-5p. [Long non-coding RNA Gm15290] (Homo sapiens) PubMed

 27930.

miR-193a-3p regulates osteoblast differentiation by modulating LGR4/ATF4 signaling and suggests that the miR-193a-3p/LGR4/ATF4 regulation axis may play an important role in regulating bone remodeling [mir193a] (Homo sapiens) PubMed

 27931.

circNUP214 may play an oncogenic role in papillary thyroid cancer by acting as a sponge for miR-145, leading to upregulation of ZEB2.[circNUP214] (Homo sapiens) PubMed

 27932.

These results confirm our initial assumption that APP alpha-secretase activity in human blood serum is mediated by complement C1.[alpha secretase] (Homo sapiens) PubMed

 27933.

The circ_0016760/miR-1287/GAGE1 signaling might play vital roles in the tumorigenesis and progression of Non-small cell lung cancer (NSCLC).[RNA circ_0016760] (Homo sapiens) PubMed

 27934.

hsa_circ_0059655 and other 14circRNAs derived from PYGB target on several similar genes by miR-338-3p.[Hsa_circRNA_0059655] (Homo sapiens) PubMed

 27935.

circHIPK3 downregulation mediates high glucose-induced endothelial cell injury.[circHIPK3] (Homo sapiens) PubMed

 27936.

the present study demonstrated that miR199 and miR122 are implicated in the pathogenesis of OLP by regulating the expression of mTOR and AKT1. (Homo sapiens) PubMed

 27937.

these data demonstrated that the miR95p/Klf4 axis was able to promote HCC progression, which may occur via regulation of the AKT signaling pathway, highlighting a potential novel target in HCC treatment. (Homo sapiens) PubMed

 27938.

Our findings indicated that IL-35 regulation to viral specific Tregs/Th17 balance may contribute to viral persistence in chronic hepatitis B virus infection [IL-35]. (Homo sapiens) PubMed

 27939.

circHIPK3 promotes lung cancer cell progression possibly by sponging miR-124.[circHIPK3] (Homo sapiens) PubMed

 27940.

Results found that Brg1 regulates acetaminophen metabolism by activating CYP3A11 transcription by modulating histone modification surrounding the proximal CYP3A11 promoter. [CYP3A11] (Homo sapiens) PubMed

 27941.

the lncRNA SNHG1 acted as an oncogene in OS cancer; it downregulated the expression of miRNA-101-3p and promoted cancer cell proliferation, migration and invasion through activating the expression of ROCK1, the PI3K/AKT pathway and EMT. (Homo sapiens) PubMed

 27942.

The results revealed an innovative function of the miR-1254 in controlling SMAD3 and pro-fibrosing elements as well as the wound healing response in LX-2, attenuating the scaring repair of the injured tissue.[Mir1254] (Homo sapiens) PubMed

 27943.

a LIN28B variant, LIN28B-TST, which is specifically expressed in hepatocellular carcinoma (HCC) and many other cancer types, is reported. [LIN28B-TST] (Homo sapiens) PubMed

 27944.

The ORF1p can form stable nucleic acid-bound oligomers in vitro is positively correlated with formation of an active L1 RNP as assayed in vivo using a cell culture-based retrotransposition assay. (LINE-1 endonuclease, human) (Homo sapiens) PubMed

 27945.

the 2 common HNA-3 variants in 9 ethnic populations residing in Sichuan and Yunnan provinces of China were explored as compared to the Han population.[HNA-3a, HNA-3b] (Homo sapiens) PubMed

 27946.

Study provides evidence that the novel identified thyroglobulin-embedded microRNA (miR-TG) plays a fine-tuning effect on the maintenance of the thyroid gland homeostasis, and the downregulation of the miR-TG expression is involved in pathogenesis of papillary thyroid carcinoma. [miR-TG] (Homo sapiens) PubMed

 27947.

Results found that Nup159 did not accelerate ADP release, while Gle1 actually slowed it independently of Mg(2+) which is not consistent with Nup159 acting as a nucleotide exchange factor to promote ADP release and Dbp5 ATPase cycling. Instead, in the presence of Nup159, the interaction between Gle1 and ADP-bound Dbp5 was found more reduced, suggesting that Nup159 alters the Dbp5-Gle1 to aid Gle1 release from Dbp5. [NUP159 (Homo sapiens) PubMed

 27948.

study demonstrated that XLOC_006390 may serve as a ceRNA and reversely regulates the expression of miR-331-3p and miR-338-3p, thus facilitating cervical cancer tumorigenesis and metastasis [LncRNA XLOC_006390 ] (Homo sapiens) PubMed

 27949.

LncRNA OR3A4 participates in the angiogenesis of hepatocellular carcinoma through modulating AGGF1/akt/mTOR pathway [OR3A4] (Homo sapiens) PubMed

 27950.

activin is a novel candidate as a clinical marker to identify those acute pancreatitis patients with severe disease who would benefit from aggressive treatment and activin may be a therapeutic target in severe acute pancreatitis.[Activin] (Homo sapiens) PubMed

 27951.

MiR-1-3p has significant effects on viability, proliferation, invasion and apoptosis of bladder cancer cells by regulating BDNF-TrkB pathway. [miRN1-3] (Homo sapiens) PubMed

 27952.

Protein encoded in human telomerase RNA is involved in cell protective pathways. [hTERP] (Homo sapiens) PubMed

 27953.

Long non-coding RNA EPIC1 inhibits viability and invasion of osteosarcoma cells by promoting MEF2D ubiquitylation [EPIC1] (Homo sapiens) PubMed

 27954.

the disease relevant lncRNA LISPR1 acts as a novel regulatory unit important for S1PR1 expression and endothelial cell function.[lncRNA LISPR1] (Homo sapiens) PubMed

 27955.

This study showed that the kcc2 is expressed in a subset of neurons throughout the song system, including HVC (used as a proper name), robust nucleus of the arcopallium (RA), lateral magnocellular nucleus of the anterior nidopallium (LMAN), Area X, and DLM. (Homo sapiens) PubMed

 27956.

miR-10b expression in peripheral blood mononuclear cells has predictive value for the tumor response to chemotherapy and prognosis for advanced non-small-cell lung cancer patients [miRNA10b] (Homo sapiens) PubMed

 27957.

miR-199-5p expression level was found to be significantly upregulated in OSF mucosa compared with normal control. OSF disease duration and OSF histological grade were significantly correlated with the high level of miR-199-5p (p = 0.028 and p = 0.012, respectively). [miR-199] (Homo sapiens) PubMed

 27958.

MicroRNA-548-3p and MicroRNA-576-5p enhance the migration and invasion of esophageal squamous cell carcinoma cells via NRIP1 down-regulation [miRN548] (Homo sapiens) PubMed

 27959.

CBX4 is up-regulated in breast cancer tissues and while its over-expression promotes cell proliferation, its knockdown suppresses cell proliferation in breast cancer cells. Furthermore, CBX4 mediates miR-129-5p-induced inhibition of cell proliferation and negatively correlates with the expression of miR-129-5p expression. [miRNA129-5] (Homo sapiens) PubMed

 27960.

long non-coding RNA PEG10 knockdown played a carcinostatic role via up-regulating miR-3200 and further regulating AEG1 in gastric carcinoma cells [lncRNA PEG10; miRN3200] (Homo sapiens) PubMed

 27961.

PICART1 acts as a tumor suppressor via regulation of JAK2/STAT3 pathway and promotes apoptosis in lung cancer cells [lncRNA PICART1] (Homo sapiens) PubMed

 27962.

Expression of low levels of EPB41L4A-AS2 is associated with poor survival in non-small cell lung cancer (NSCLC) and the over-expression of lncRNA EPB41L4A-AS2 inhibits NSCLC cell proliferation, invasion and promote cell apoptosis. (Homo sapiens) PubMed

 27963.

Significant downregulation of lncRNA AC008440.10 was detected in laryngeal squamous cell carcinoma (LSCC) tumor and metastatic lymph node in advanced stage. lncRNA AC008440.10 is a promising tumor marker for LSCC. [lncRNA AC008440.10] (Homo sapiens) PubMed

 27964.

this study show that IL-1 and IL-36 represent parallel epithelial cell-driven protective pathways in immunity to oral Candida albicans infection (Homo sapiens) PubMed

 27965.

reported a novel lncRNA, CTC-505O3 (lncRNA DRHC), that was downregulated in hepatocellular carcinoma and its low expression was associated with dismal survival[lncRNA DRHC] (Homo sapiens) PubMed

 27966.

CARlo-7/lnc00990 can act as a prognostic marker for bladder cancer. (Homo sapiens) PubMed

 27967.

our data indicate that OTG functions as a novel negative regulator of Wnt signaling during development by the modulation of cell surface expression of Fz receptor. (Homo sapiens) PubMed

 27968.

We conclude that LncRNA AWPPH may promote the growth of triple-negative breast cancer by up-regulating FZD7 (Homo sapiens) PubMed

 27969.

lncRNA snaR overexpression inhibited cancer cell migration and invasion, while TGF-b1 treatment attenuated the inhibitory effect of lncRNA snaR overexpression on cancer cell migration and invasion. We therefore conclude that down-regulation of lncRNA snaR may induce postoperative DR of HPV-negative CSCC possibly through the interactions with TGF-b1. (Homo sapiens) PubMed

 27970.

BLOC-2 and BLOC-3 were destabilized due to the mutation of these Hermansky-Pudlak syndrome (HPS) genes which are so far the only reported causative genes in Chinese HPS patients[bloc2] (Homo sapiens) PubMed

 27971.

BORG elicits the metastatic outgrowth of latent breast cancer cells by promoting the localization and transcriptional repressive activity of TRIM28, which binds BORG and induces substantial alterations in carcinoma proliferation and survival (Homo sapiens) PubMed

 27972.

L1-5'UTR harbors both sense and antisense promoter activity and a dsRNA-mediated regulation is responsible for L1-5'UTR regulation. Agos proteins and L1-ORF1p were engaged in this process. [L1-ORF1p] (Homo sapiens) PubMed

 27973.

miR-515-5p is down-regulated, and associated with the malignant status and prognosis in prostate cancer patients. MiR-515-5p acts as a tumor suppressor to regulate cell proliferation, migration and invasion via targeting TRIP13 in prostate cancer. (Homo sapiens) PubMed

 27974.

lncRNA OCC-1 can regulate the levels of a large number of mRNAs at post-transcriptional level through modulating RBP HuR stability (lncRNA OCC-1). (Homo sapiens) PubMed

 27975.

Study found that lnc-DILC was downregulated in human bladder cancer (BC) tissues and suggests that lnc-DILC is a novel bladder tumor suppressor and indicate that inhibits BC progression via inactivating STAT3 signaling. [Lnc-DILC] (Homo sapiens) PubMed

 27976.

plasma IL-35 levels may be associated with the development and progression of breast cancer [IL35] (Homo sapiens) PubMed

 27977.

mir-486-3p, mir-486-5p, and mir-155-5p may contribute to the development of secondary erythrocytosis and thrombocytopenia in cyanotic children following hypoxia [mir486-3 and mir486-5] (Homo sapiens) PubMed

 27978.

Our results demonstrated for the first time that IL-35 played a critical role in modulating not only adaptive immune response, but also innate immune response [IL-35]. (Homo sapiens) PubMed

 27979.

it was revealed that AWPPH may promote OC via activation of the Wnt/betacatenin signaling pathway. (Homo sapiens) PubMed

 27980.

the present study demonstrated that miR-512-5p is significantly downregulated in NSCLC tissues and cells, and may regulate ETS1 expression to affect NSCLC cell proliferation, migration, invasion and apoptosis. (Homo sapiens) PubMed

 27981.

let-7a-5p was downregulated in DN and that let-7a-5p may participate in the pathogenesis of DN by targeting the HMGA2/PI3K/AKT signaling pathway. The results present let-7a-5p as a potential diagnostic marker and therapeutic targets for the diagnosis and treatment of DN. (Homo sapiens) PubMed

 27982.

The present results suggested that miR101 may serve a role in colon cancer by directly targeting CREB1. Collectively, the present study may contribute to the development of improved diagnosis and prognostics for colon cancer. (Homo sapiens) PubMed

 27983.

the present results suggested that circRNACER may serve an important role in the progression of breast cancer by regulating the activity of the miR136/MMP13 axis, and may be a potential biomarker for the prediction and treatment of breast cancer. (Homo sapiens) PubMed

 27984.

circHIPK3 regulated xenograft tumor growth via the miR-124-AQP3 axis. (Homo sapiens) PubMed

 27985.

inhibits KSHV, EBV, HSV-2 infection of cells via stifling expression of interferon induced transmembrane protein 1 (IFITM1) - [miRAN-36] (Homo sapiens) PubMed

 27986.

Serum IL-35 levels were associated with low disease activity, in contrast with serum IL-12p70 levels, which were associated with more active disease[il35] (Homo sapiens) PubMed

 27987.

miR-9-5p exerted a neurotoxic role in MPP(+)-derived PD by directly targeting STAT1. [miR-9-5p] (Homo sapiens) PubMed

 27988.

Serum levels of CA19-9 are elevated in patients with cholangiocarcinoma.[CA19-9] (Homo sapiens) PubMed

 27989.

Here we show that over-expression of SPATA31A1 in fibroblast cells leads to premature senescence due to interference with aging-related transcription pathways. We propose that the evolution of SPATA31 copy number is an example for antagonistic pleiotropy by providing a fitness benefit during the reproductive phase of life, but negatively influencing the overall life span. (Homo sapiens) PubMed

 27990.

(miR-516a-5p) MIRN-516a-5p functions as a tumor suppressive factor in non-small cell lung cancer cells by targeting HIST3H2a. (Homo sapiens) PubMed

 27991.

Study found lncUEGC1 and lncUEGC2 to be remarkably up-regulated in exosomes derived from early gastric cancer (EGC) patients. Stability testing demonstrates that almost all the plasma lncUEGC1 was encapsulated within exosomes and thus protected from RNase degradation. Exosomal lncUEGC1 may be promising in the development of highly sensitive, stable, and non-invasive biomarkers for EGC diagnosis. [lncUEGC1, lncUEGC2] (Homo sapiens) PubMed

 27992.

our study indicates that knockdown of MALAT1 reverses chemoresistance to TMZ via promoting miR-101 regulatory network in GBM and thus offers a novel prognostic marker and potential target for GBM TMZ-based chemotherapy. (Homo sapiens) PubMed

 27993.

circRNA_104916 is downregulated in colorectal cancers as compared to the adjacent normal tissues [circRNA_104916] (Homo sapiens) PubMed

 27994.

Data indicate that lncRNA-OIS1 links oncogenic induction and senescence with the activation of the tumor suppressor DPP4 (lncRNA-OIS1). (Homo sapiens) PubMed

 27995.

LAP2alpha promotes or inhibits proliferation of progeria cells depending on the level of A-type lamins in the nuclear interior.[Lap2alpha] (Homo sapiens) PubMed

 27996.

RMEL3 overexpression, in immortalized fibroblasts and melanoma cells, increased proliferation and survival under serum starvation, clonogenic ability, and xenografted melanoma tumor growth.[RMEL3] (Homo sapiens) PubMed

 27997.

our study provide evidence of the coordination of miR-24 and WWOX in the regulation of cell apoptosis, proliferation, and migration during NSCLC development. Inhibition of miR-24 expression may serve as an alternative treatment modality for NSCLC. (Homo sapiens) PubMed

 27998.

lncRNA SNHG20 regulated PI3K/Akt/mTOR signaling pathway to promote tumorigenesis and stemness of glioblastoma [lncRNA SNHG20] (Homo sapiens) PubMed

 27999.

pro-proliferative role of lncRNA BCAR4 in NTHY-ORI 3-1 cells and human primary thyrocytes [LncRNA BCAR4] (Homo sapiens) PubMed

 28000.

Logistic regression analysis results indicated that smoking, uric acid (UA) levels, 2 hour C-peptide and standard deviation of blood glucose (SDBG) were the influence factors for carotid artery intima-media thicknessthickening.[C peptide] (Homo sapiens) PubMed

 28001.

PLAC2 long non-coding RNA upregulates p53 to mediate hepatocellular carcinoma cell apoptosis [PLAC2 long non-coding RNA] (Homo sapiens) PubMed

 28002.

lncRNA-ZNF281 inhibits the self-renewing ability and invasion of glioma stem-like cells in vitro and in vivo and can reduce tumorigenicity in the glioma stem-like cell [lncRNA-ZNF281] (Homo sapiens) PubMed

 28003.

A long non-coding RNA ENST00000425894 termed gallbladder cancer drug resistance-associated lncRNA1 (GBCDRlnc1) serves as a critical regulator in gallbladder cancer chemoresistance. [GBCDRlnc1 lncRNA] (Homo sapiens) PubMed

 28004.

Study identified a new lncRNA, URRCC, whose expression is upregulated in clear cell renal cell carcinoma (ccRCC) samples and associated with poor prognosis, leading to promote ccRCC cell proliferation and invasion. [URRCC] (Homo sapiens) PubMed

 28005.

The results demonstrated that interactions between ameloblastoma cells and bone marrow stromal cells (BMSCs) increased interleukin (IL)8 and activin A secretion by BMSCs. [activin A] (Homo sapiens) PubMed

 28006.

Fractions enriched in nanosized RNAcarriers were separated from the plasma of young participants in this study with Down syndrome and their nontrisomic siblings and miRNAs were extracted. A microarraybased analysis on a small cohort of samples led to the identification of the three most abundant miRNAs, namely miR165p, miR99b5p and miR1443p. [miR-16-5] (Homo sapiens) PubMed

 28007.

Novel lncRNA-IUR suppresses Bcr-Abl-induced tumorigenesis through regulation of STAT5-CD71 pathway. [IUR lncRNA] (Homo sapiens) PubMed

 28008.

N6-methyladenosine-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1. [RP11-138 J23.1 lncRNA] (Homo sapiens) PubMed

 28009.

these results indicated that LncRNA AB073614 may serve as a prognostic biomarker and potential target of treatment for EOC. (Homo sapiens) PubMed

 28010.

Kaplan-Meier analysis indicated that low levels of TCONS_00027978 expression were associated with poorer overall survival [TCONS_00027978] (Homo sapiens) PubMed

 28011.

Here, we identified an mRNA quality control factor Dom34 as a novel restriction factor for a positive-sense single-stranded RNA virus. Downregulation of Dom34 and RNase L increases viral replication, as well as half-life of the viral RNA. [Dom34] (Homo sapiens) PubMed

 28012.

circRNA1656 has the potential to serve as a novel tumor marker for high-grade serous ovarian cancer.[circRNA1656] (Homo sapiens) PubMed

 28013.

study found a very high specificity and strong positive predictive value for the combination of HBME-1 and CD56 immunohistochemical stains [HBME1] (Homo sapiens) PubMed

 28014.

HE4, CA125, and CA72-4 are expressed differently and may be used to predict postoperative recurrence of ovarian cancer [CA72-4] (Homo sapiens) PubMed

 28015.

These data suggest the oncogenic function of the novel fusion gene VAPA-Rab31 via upregulated Bcl-2 and activated CREB in lung cancer.[VAPA-Rab31] (Homo sapiens) PubMed

 28016.

miR-374b promotes glioma process in vitro through suppressing SEMA3B via targeting GATA3 [miR-374b] (Homo sapiens) PubMed

 28017.

miR-125b1 promoter methylation correlated with gastric cancer tumor location and stages [miR-125b1] (Homo sapiens) PubMed

 28018.

circMTO1 was able to sponge miR-221 and overexpression of circMTO1 negatively regulated the E-cadherin/N-cadherin pathway to inhibit bladder cancer cells' epithelial-to-mesenchymal transition by competing for miR-221.[circMTO1] (Homo sapiens) PubMed

 28019.

miR-376b-3p and KLF12 are involved in TTN-AS1-mediated gastric cancer progression [miR-376b] (Homo sapiens) PubMed

 28020.

lncBRM was highly expressed in colorectal cancer and sponged miR-204-3p to modulate the expression of TPT1.[lncBRM] (Homo sapiens) PubMed

 28021.

Long noncoding RNA TCF7 facilitated human airway smooth muscle cell growth and migration via targeting TIMMDC1 thus activating AKT signaling.[lncRNA TCF7] (Homo sapiens) PubMed

 28022.

these data suggest that Serpina3n may represent a circulating biomarker of muscle atrophy associated to GC and, broadly, a reflection of dynamic changes in muscle mass. (Homo sapiens) PubMed

 28023.

Treatment with si-linc-GPR65-1 significantly down-regulated slug protein associated with epithelial mesenchymal transition. linc-GPR65-1 promotes gastric cancer cell proliferation and metastasis by activating slug expression. (Homo sapiens) PubMed

 28024.

These results identify PITA and PISA as selective regulators of p53-mediated glycolysis and mitochondrial respiration.[PITA, PISA] (Homo sapiens) PubMed

 28025.

MiR-125b-5p increase is associated with severity of liver damage in chronic hepatitis B patients with acute-on-chronic liver failure [miR125B5] (Homo sapiens) PubMed

 28026.

MOTS-c associates positively with insulin resistance mostly in lean individuals.[MOTS-c] (Homo sapiens) PubMed

 28027.

the activation of MLC is implicated in IL-6-mediated podocyte hypermotility.[MLC] (Homo sapiens) PubMed

 28028.

According to the current literature, pediatric high-grade glioma patients positive for the H3K27M mutation are more than 3 times more susceptible to succumbing to this disease by more than 2 years, compared to patients negative for the mutation. (Homo sapiens) PubMed

 28029.

This study showed that serum CNPY2 isoform 2 may be a valuable biomarker for the early detection of colorectal cancer and presents an improvement in the diagnostic efficiency by combination of CEA and CA19-9.[CA 19-9] (Homo sapiens) PubMed

 28030.

These results suggest that the serum tumor-associated glycoprotein 72 (TAG-72) value is a clinically helpful predictor of lymph nodes invasion in resectable esophagogastric junction adenocarcinoma. [tumor-associated glycoprotein 72] (Homo sapiens) PubMed

 28031.

circHECTD1 functions as an endogenous MIR142 (microRNA 142) sponge to inhibit MIR142 activity, resulting in the inhibition of TIPARP (TCDD inducible poly[ADP-ribose] polymerase) expression with subsequent inhibition of astrocyte activation via macroautophagy/autophagy.[circHECTD1] (Homo sapiens) PubMed

 28032.

mirn24-3p has a role as a promigratory microRNA in mesothelioma [miR-24-3p] (Homo sapiens) PubMed

 28033.

demonstrate that BAF45d splicing is mediated by polypyrimidine tract-binding protein 1 (PTBP1) and that BAF45d regulates PTBP1[baf45d] (Homo sapiens) PubMed

 28034.

Expression of miR-26R in ovarian cancer tissues [miR-26R] (Homo sapiens) PubMed

 28035.

This study suggested that miR-9-5p regulates GOT1 expression in pancreatic cancer, thereby stunting proliferation, invasion, glutamine metabolism and redox homeostasis, and that miR-9-5p may serve as a prognostic or therapeutic target for pancreatic cancer. [miR-9-5p] (Homo sapiens) PubMed

 28036.

Autoimmune pancreatitis patients with laminin 511-E8 antibodies exhibited distinctive clinical features, as the frequencies of malignancies or allergic diseases were significantly lower in patients with laminin 511-E8 antibodies than in those without.[Laminin 511] (Homo sapiens) PubMed

 28037.

lnc-TSI reduced renal fibrogenesis through negative regulation of the TGF-beta/Smad pathway.[lnc-TSI] (Homo sapiens) PubMed

 28038.

the combined actions of SNP in lncRNAPVT1 Rs13281615 and miR-146a Rs2910164 affected the lung function in chronic obstructive pulmonary disease smokers (lncRNAPVT1). (Homo sapiens) PubMed

 28039.

Results suggest that NR_102714 and its associated protein-coding gene UCHL1 might be involved in the development of chronic obstructive disease. [NR_102714] (Homo sapiens) PubMed

 28040.

Study identifies a novel cytoplasmic intergenic lincRNA (MIRAT), which is upregulated following prolonged MAPK inhibition in NRAS mutant melanoma and modulates MAPK signaling by binding to the MEK scaffold protein IQGAP1. [LncRNA MALAT] (Homo sapiens) PubMed

 28041.

the combination of CXC chemokine receptor 4 plus HBME-1 provided absolute value of sensitivity and negative predictive value in the same group of lesions in papillary thyroid carcinoma [HBME-1] (Homo sapiens) PubMed

 28042.

This study suggests that dendroaspis natriuretic peptide can be anticipated among molecules leading development of vasospasm [dendroaspis natriuretic peptide] (Homo sapiens) PubMed

 28043.

accuracy of Core needle biopsy of thyroid nodules is increased by adding Galectin-3, Cytokeratin-19, and HBME-1 to the panel [HBME-1] (Homo sapiens) PubMed

 28044.

The function of PAFAH1B1 required the presence of the intact protein as overexpression of NONHSAT073641 [NONHSAT073641] (Homo sapiens) PubMed

 28045.

Expression and function of lnc-C/EBPbeta in the myeloid-derived suppressor cells,[lnc-C/EBPbeta] (Homo sapiens) PubMed

 28046.

The outcome of this study illustrated that LINC00483 promoted colorectal cancer cells proliferation and metastasis via modulating FMNL2 by acting as a competitive RNA of miR-204-3p. [LINC00483 lncRNA] (Homo sapiens) PubMed

 28047.

the expression and function of PR-LncRNAs are significantly altered in gliomagenesis and that their activity is mediated by SOX factors.[PR-LncRNA] (Homo sapiens) PubMed

 28048.

Plasma miRNA-1254 predicted changes in LV volumes and LVEF at 6 months after STEMI. The value of miR-1254 to inform tailored treatment selection and monitor ongoing efficacy deserves further investigation. (Homo sapiens) PubMed

 28049.

our study presents novel findings that delineate the role of SHLP2 as a mitochondria-targeting protective molecule that confers both morphological and functional protection against cellular and mitochondrial toxicity. (Homo sapiens) PubMed

 28050.

LAMP2A can potentiate autophagic flux in the Drosophila brain, leading to enhanced stress resistance and neuroprotection. [LAMP2A] (Homo sapiens) PubMed

 28051.

SCC-S2 Facilitates Tumor Proliferation and Invasion via Activating Wnt Signaling and Depressing Hippo Signaling in Colorectal Cancer Cells and Predicts Poor Prognosis of Patients [Hippo] (Homo sapiens) PubMed

 28052.

Low-expression of lncRNA FER1L4 might be a prognostic marker in osteosarcoma (Homo sapiens) PubMed

 28053.

Circ_0000735 exerts oncogenic properties in non-small cell lung cancer cells which is partly dependent on its regulation on miR-1179 and miR-1182 (Circ_0000735). (Homo sapiens) PubMed

 28054.

demonstrates that downregulation of hsa_circ_0007534 represses the proliferation and invasion of cervical cancer through regulating the miR-498/BMI-1 axis[circ_0007534] (Homo sapiens) PubMed

 28055.

present the first evidence that DLIC1 and DLIC2 have distinct roles in colon cancer development[dlic2] (Homo sapiens) PubMed

 28056.

Overexpression of circ-RAD23B was associated with lymph node metastasis, poorer differentiation grade and shorter 5-year survival time (circ-RAD23B). (Homo sapiens) PubMed

 28057.

These results demonstrate a novel regulatory axis of malignant cell proliferation and invasion in gastric cancer, comprising GCRL1, miR-885-3p, and CDK4.[LncRNA GCRL1] (Homo sapiens) PubMed

 28058.

linc00462/miR-665/TGFBR1/2 regulatory network may shed light on tumorigenesis in prostate cancer.[linc00462] (Homo sapiens) PubMed

 28059.

circ_0025033 RNA, miR-1231, and miR-1304 are involved in parathyroid cancer initiation and progression [circ_0025033 RNA] (Homo sapiens) PubMed

 28060.

dysregulation of miR-195-5p/-218-5p/BIRC5 axis predicts a poor prognosis in patients with gastric cancer [miRN218-5] (Homo sapiens) PubMed

 28061.

this research supports the first evidence that AGAP2-AS1 plays an oncogenic role in HCC via AGAP2-AS1/miR-16-5p/ANXA11/AKT axis pathway and represents a promising therapeutic strategy for HCC patients. (Homo sapiens) PubMed

 28062.

CASC2 inhibited cell viability and the colony formation, migration, and invasion abilities of Hepatocellular carcinoma cells by directly downregulating miR-183 through inactivation of the Wnt/beta-catenin signaling pathway.[lncRNA CASC2] (Homo sapiens) PubMed

 28063.

RP11-513G11.1 is highly expressed in patients with diffuse large B-cell lymphoma (DLBCL), which is related with the prognosis of DLBCL patients (Homo sapiens) PubMed

 28064.

HCP5 promoted proliferation of cervical cancer cells, which was reversed by microRNA-15a knockdown and Overexpressed HCP5 promoted the development of cervical cancer through increasing MACC1 expression by microRNA-15a adsorption. (HCP5 long noncoding RNA, human) (Homo sapiens) PubMed

 28065.

miR-101-3p inhibits ATX regulation by directly targeting a conserved sequence in the ATX mRNA 3'UTR. Moreover, there was an inverse correlation between ATX and miR-101-3p levels in various types of cancer cells. [miR 101-3p] (Homo sapiens) PubMed

 28066.

TIS111D may participate in the regulation of bladder cancer progression by regulating epithelial-mesenchymal transition [TIS111D] (Homo sapiens) PubMed

 28067.

Cooperative physical interactions among eEF1BdeltaL, RNF20/40, and HSF1 synergistically promote expression of heat shock-responsive genes. In addition, eEF1BdeltaL is a novel ubiquitylation target of RNF20/40 and elucidating its function. This provides a molecular mechanism for the cooperative function of distinct transcription factors in heat shock-responsive gene transcription (eEF1BdeltaL). (Homo sapiens) PubMed

 28068.

we demonstrated for the first time the oncogenic role of LINC00152 in ovarian cancer. An increased LINC00152 level is associated with poor prognosis for ovarian cancer patients. Silencing of LINC00152 dramatically declined ovarian cancer cell growth and caused apoptosis in vitro and in vivo by acting as a ceRNA target of miR-125b to downregulate MCL-1 expression and induce mitochondrial-dependent cell death inhibition. (Homo sapiens) PubMed

 28069.

miR-19 and miR-21 are highly expressed in peripheral blood of patients with undifferentiated lung cancer [miRNA19] (Homo sapiens) PubMed

 28070.

DCST1-AS1 up-regulates the expression of FAIM2 by up-regulating the expression of miR-1254, ultimately promoting the proliferation of hepatocellular carcinoma cells. (Homo sapiens) PubMed

 28071.

the SLC47A2 locus highly expresses SANT1, which can remove the regulatory SFPQ/E2F1/HDAC1 suppressor complex from the promoter region.[lncRNA SANT1] (Homo sapiens) PubMed

 28072.

Long non-coding RNA BCAR4 may activate GLI2 signaling in prostate cancer cells to contribute to castration resistance. (Homo sapiens) PubMed

 28073.

LINC01016-miR-302a-3p/miR-3130-3p/NFYA/SATB1 axis played a crucial role in the occurrence of endometrial cancer.[LINC01016] (Homo sapiens) PubMed

 28074.

NONHSAT062994 showed no consistently differential expression in GSE2637dataset[NONHSAT062994] (Homo sapiens) PubMed

 28075.

A novel lncRNA, TCONS_00006195, represses hepatocellular carcinoma progression by inhibiting enzymatic activity of ENO1. [lncRNA TCONS_00006195, human] (Homo sapiens) PubMed

 28076.

Variant of SNP rs1317082 at CCSlnc362 (RP11-362K14.5) creates a binding site for miR-4658 and diminishes the susceptibility to colorectal cancer. [RP11-397D12.4 lncRNA, human] (Homo sapiens) PubMed

 28077.

circ-GRB10 might be a novel therapeutic target for Intervertebral disc degeneration.[circ-GRB10] (Homo sapiens) PubMed

 28078.

LINC01436 exerted biological functions by acting as a microRNA (miR)-30a-3p sponge to regulate the expression of its target gene EPAS1.[LINC01436] (Homo sapiens) PubMed

 28079.

LncKLHDC7B (ENSG00000226738) acts as a transcriptional modulator of its neighboring coding gene KLHDC7B in the immunomodulatory subtype.(ENSG00000226738) (Homo sapiens) PubMed

 28080.

Circular RNA Itchy E3 ubiquitin protein ligase (Circ-ITCH) sponges miR-10a to suppress the proliferation/apoptosis of human ovarian epithelial cells. (Homo sapiens) PubMed

 28081.

circMTO1 could act as a tumor suppressor affecting the growth and invasion of colorectal cancer cells by regulating Wnt/beta-catenin signaling pathway. (Homo sapiens) PubMed

 28082.

In gastric cancer circ_0009910 acts as a prognostic biomarker and promote cell proliferation, migration, invasion and epithelial mesenchymal transformation. (Homo sapiens) PubMed

 28083.

LINC00675 acts as a tumor suppressor in esophageal squamous cell carcinoma by regulating of Wnt/beta-catenin signaling pathway. (Homo sapiens) PubMed

 28084.

These data demonstrate a key role for proteolysis of the C-terminal of APP by gamma-secretase in neuronal dysfunction in monogenic Alzheimer's disease.[Gamma secretase] (Homo sapiens) PubMed

 28085.

Circulating lncRNA ITSN1-2 is upregulated, and its high expression associates with increased disease severity and inflammation as well as poor prognosis in sepsis patients. [ ITSN1-2] (Homo sapiens) PubMed

 28086.

DQ786243 promoted ovarian cancer-cell growth through miR-506-dependent CREB1 regulation.DQ786243 was upregulated and predicted poor clinical prognosis in ovarian cancer.[DQ786243] (Homo sapiens) PubMed

 28087.

hsa_circ_100395 regulates lung cancer cell proliferation, migration and invasion through modulating miR-1228/TCF21 pathway.[hsa_circ_100395] (Homo sapiens) PubMed

 28088.

Dido3 is an adaptor that controls SFPQ utilization in RNA splicing [Dido3] (Homo sapiens) PubMed

 28089.

claudin-4-mediated interfaces can drive partitioning of extracellular membrane proteins with ectodomains as small as 5 nm but not of inner or outer leaflet lipids (Homo sapiens) PubMed

 28090.

Our results indicated that hsa_circ_001569 upregulation was associated with BC lymph-node metastasis, clinical stage, and poor prognosis. Hsa_circ_001569 might contribute to progression of BC by modulating PI3K-AKT pathway. (Homo sapiens) PubMed

 28091.

These results identified that the FZD7-TWIST1 axis is important for tumorigenesis and anoikis resistance, and therapeutic inhibition results in cell death in ovarian cancer.[FZD7] (Homo sapiens) PubMed

 28092.

we found that miR-101 is markedly downregulated and inversely associated with CXCL12 expression in PTC tissues and cells. Clinically, miR-101 downregulation is positively associated with advanced histological stages and lymph node and distant metastases. (Homo sapiens) PubMed

 28093.

Overexpression of miR-129-5 inhibited the expression of Wnt5a, thus blocking the protein kinase C(PKC)/ERK/NF-kappaB and JNK pathways.[miR-129-5] (Homo sapiens) PubMed

 28094.

present study provides the first evidence that the expression level of lnc-AL445665.1-4 is increased in multiple uterine leiomyomas compared to that in solitary uterine leiomyomas .[Lnc-AL445665.1-4] (Homo sapiens) PubMed

 28095.

Study identified miR-3687 as one of the highly expressed miRNAs in basaloid squamous cell carcinoma of the oesophagus (BSCCE). Also, miR-3687 was found to target PGRMC2. [miR-3687] (Homo sapiens) PubMed

 28096.

Inhibition of miR-129-5p can suppress alcohol-induced intestinal epithelial permeability. [miR129-5] (Homo sapiens) PubMed

 28097.

There is a link between up-regulation of miR-23a/b-3p and the coincident down-regulation of four expressed genes in the sperm of men with oligoasthenozoospermia, compared with men with normozoospermia. (Homo sapiens) PubMed

 28098.

Long non-coding RNA CRRL (NONHSAG00767) suppresses cardiomyocyte regeneration by directly binding to miR-199a-3p, indicating that loss of CRRL facilitates myocardial regeneration and may be a new potential therapeutic strategy for heart failure. (Homo sapiens) PubMed

 28099.

lncRNA CCHE1 may promote the proliferation and inhibit apoptosis of gastric cancer cells. (Homo sapiens) PubMed

 28100.

LncRNA RP11-37B2.1 single-nucleotide polymorphisms rs218916 and rs160441 significantly associate with the occurrence of thrombocytopenia resulted from antituberculosis drugs treatment in Chinese patients.No significant association between LncRNA RP11-37B2.1 single-nucleotide polymorphisms rs218916 and rs160441 and susceptibility of tuberculosis.[lncRNA RP11-37B2.1] (Homo sapiens) PubMed

 28101.

CircHIPK3 facilitated nasopharyngeal progression by protecting ELF3 from miR-4288-mediated gene silencing. (Homo sapiens) PubMed

 28102.

MiR-1-3p role in overcoming HGF-induced gefitinib resistance in EGFR mutant lung cancer cell.Mir-1-3p inhibits epithelial-mesenchymal transition in the lung cancer cells through inhibition of c-Met signaling. [mir-1-3p] (Homo sapiens) PubMed

 28103.

further investigation revealed that lncRNA AC003092.1 regulates TFPI-2 expression through miR-195 in glioblastoma (GB). Taken together, these data suggest that lncRNA AC003092.1 could inhibit the function of miR-195 by acting as an endogenous CeRNA, leading to increased expression of TFPI-2; this promotes TMZ-induced apoptosis, thereby making GB cells more sensitive to TMZ. (Homo sapiens) PubMed

 28104.

Preoperative-CEA was elevated (>/=5.0 ng/mL) in 73.6% of the colorectal cancer patients and remained elevated after surgery in 32.7% of the patients. Elevated postoperative-CA 19-9 (>/=50 U/mL) was observed in 9.5% of the patients. Neither elevated pre-CEA nor elevated pre-CA 19-9 was associated with relapse-free survival (RFS) but both elevated post-CEA and elevated post-CA 19-9 were associated with reduced ...[CA-19-9] (Homo sapiens) PubMed

 28105.

IL-35 The aim of this study was to clarify the effect of IL-35 on IL-6 and IL-8 production in human periodontal ligament cells (HPDLCs) stimulated with IL-17A. Our findings suggested that IL-35 produced from regulatory T cells might inhibit progression of periodontitis by decreasing IL-17A-induced levels of IL-6 and IL-8. (Homo sapiens) PubMed

 28106.

Study identified lncPKD223 to be associated with pejorative cholangiocarcinoma (CCA) features and poor prognosis, and may serve as a cancer stem cell (CSC) marker. In addition, lncPKD223 overexpression increased sphere formation efficiency and enhanced drug resistance to 5FU in CCA cell lines. [lncPKD223] (Homo sapiens) PubMed

 28107.

lncRNA-Neighboring Enhancer of FOXA2 (NEF) inhibit the proliferation, migration and invasion of esophageal squamous-cell carcinoma cells by inactivating the wnt/beta-catenin signaling pathway. (Homo sapiens) PubMed

 28108.

Results suggested that exosomal lnc-MMP2-2 might regulate the migration and invasion of lung cancer cells into the vasculature by promoting MMP2 expression. [lnc-MMP2-2] (Homo sapiens) PubMed

 28109.

LncRNA-TWIST1 promoted osteogenic differentiation both in PPDLSCs (periodontal mesenchymal stem cells from periodontitis patients) and in HPDLSCs (periodontal mesenchymal stem cells from healthy microenvironment) by inhibiting the TWIST1 expression (LncRNA-TWIST1). (Homo sapiens) PubMed

 28110.

Long non-coding RNAs NR-026690 and ENST00000447867 are upregulated in CD4(+) T cells in COPD patients. They might affect RAPGEF3 as miRNA sponges to regulate COPD development. (Homo sapiens) PubMed

 28111.

Study report that LncRNA GLCC1 stabilizes c-Myc from ubiquitination degradation in cytoplasm by combining with HSP90AA1 chaperon and consequently specifies the pattern of transcription on its target genes. Clinically, GLCC1 is associated with tumorigenesis, tumor size and predicts poor prognosis. Thus, GLCC1 is mechanistically, functionally, and clinically oncogenic in colorectal cancer.[LncRNA GLCC1] (Homo sapiens) PubMed

 28112.

circADAMTS13 can serve as a tumor suppressor during hepatocellular carcinoma progression via the functional pathway of sponging miR-484.[circADAMTS13] (Homo sapiens) PubMed

 28113.

MLL1-ZC3H13 fusion induced chromosomal instability, affected mitotic progression, and enhanced tumorsphere formation.[MLL1-ZC3H13] (Homo sapiens) PubMed

 28114.

our study revealed miR-153-3p expression was decreased in ALL cell lines and patients. Moreover, we provided evidence that miR-153-3p regulates cell proliferation, migration, and invasion by repressing ING2 expression. (Homo sapiens) PubMed

 28115.

Overexpression of circ-10021 promotes the proliferative and migratory capacities of breast cancer cells by sponging microRNA-485-3p to upregulate the NTRK3 expression. (Homo sapiens) PubMed

 28116.

cg20783223 and cg13332552, colocalized in the promoter region of BCAT1 and miR-2504 (Homo sapiens) PubMed

 28117.

The present study showed that mir-548 can be considered as potential targets in prostate cancer therapy (Homo sapiens) PubMed

 28118.

These results identify a novel inhibitor of PP4 that inhibits PP4-mediated cellular functions and establish the physiological importance of this regulation.[PP4IP] (Homo sapiens) PubMed

 28119.

hsa-miR-1975 was the most up-regulated small RNA in influenza virus-infected cells. The amount of intracellular hsa-miR-1975 increased in the late stage of the influenza virus replication cycle. The increased hsa-miR-1975 was at least partially derived from degradation of Y5RNA as a result of cellular apoptosis.[miR-175] (Homo sapiens) PubMed

 28120.

The expression of GCRG213p in complete intestinal metaplasia was significantly higher than in incomplete intestinal metaplasia (Homo sapiens) PubMed

 28121.

These data indicated that miR421 may act as an oncogene through the effects of HOPX on the Wnt/bcatenin signaling pathway and may provide insight into the mechanisms underlying carcinogenesis and the identification of potential biomarkers associated with nonsmall cell lung cancer (NSCLC). (Homo sapiens) PubMed

 28122.

The lncRNA P21 associated ncRNA deoxyribonucleic acid damage activated (PANDA) expression in bladder cancer [The lncRNA P21 associated ncRNA deoxyribonucleic acid damage activated] (Homo sapiens) PubMed

 28123.

The combined detection of CA19-9 and B7-H4 could become a new method for the clinical diagnosis and prognosis of pancreatic cancer. (Homo sapiens) PubMed

 28124.

lncRNA FAM99A is downregulated in preeclampsia and exerts a regulatory effect on trophoblast cell invasion, migration and apoptosis. [lncRNA FAM99A] (Homo sapiens) PubMed

 28125.

knockdown of HCP5 exerted anti-tumor effect via sponging miR-128-3p in Anaplastic thyroid cancer.[HCP5] (Homo sapiens) PubMed

 28126.

the interaction of lncRNA RP11-732M18.3 with 14-3-3beta/alpha increases the degradation of the p21 protein. lncRNA RP11-732M18.3 promoted the recruitment of ubiquitin-conjugating enzyme E2 E1 to 14-3-3beta/alpha and the binding of 14-3-3beta/alpha with ubiquitin-conjugating enzyme E2 E1 (UBE2E1) promoted the degradation of p21. (Homo sapiens) PubMed

 28127.

this study revealed the novel mechanism of circHIAT1 in hepatocellular carcinoma.[circHIAT1] (Homo sapiens) PubMed

 28128.

silencing circ_0010729 activated mTOR and MEK/ERK pathways by up-regulating miR-145-5p.[circ_0010729] (Homo sapiens) PubMed

 28129.

This study unveils a novel biomarker panel consisting of the hsa_circ_0058124/NOTCH3/GATAD2A axis which is critical for papillary thyroid cancer (PTC) tumorigenesis and invasiveness and may represent a novel therapeutic target for intervening in PTC progression. (Homo sapiens) PubMed

 28130.

LINC00324 promotes proliferation/metastasis but inhibits apoptosis of lung adenocarcinoma cells by sponging miR-615-5p to promote AKT1 expression. (Homo sapiens) PubMed

 28131.

Results identified a novel lncRNA, CAAlnc1, which was found to suppress adipogenesis by blocking binding of HuR, an RNA binding protein, to adipogenic transcription factor mRNAs. [CAAlnc1] (Homo sapiens) PubMed

 28132.

ARIEL recruits mediator proteins to the ARID5B enhancer, promotes enhancer-promoter interactions, and activates the expression of ARID5B, thereby positively regulating the TAL1-induced transcriptional program and the MYC oncogene. (Homo sapiens) PubMed

 28133.

this is the first study to demonstrate that the inhibitory effect of ERbeta on the migration and invasion of breast cancer cells was mediated by CLDN6, which induced the beclin1-dependent autophagic cascade. (Homo sapiens) PubMed

 28134.

the present study revealed that circRNA CBL.11expression is significantly increased in CRC cells after carbon ion irradiation. Functionally and mechanistically, circRNA CBL.11 regulates YWHAE expression by sponging miR-6778-5p directly to suppress cell proliferation in colorectal cancer. (Homo sapiens) PubMed

 28135.

elevated pre-operative presepsin was associated with major adverse cardiovascular and cerebrovascular events and improved NT-proBNP-based risk assessment in elevated-risk patients undergoing noncardiac surgery (Homo sapiens) PubMed

 28136.

high expression of ENST00000429227.1 may be an independent risk factor affecting the prognosis of hepatocellular carcinoma patients.[lncRNA ENST00000429227.1] (Homo sapiens) PubMed

 28137.

lncRNA-D16366 was decreased in hepatocellular carcinoma.[lncRNA-D16366] (Homo sapiens) PubMed

 28138.

these results suggested that circRBMS3 promoted Gastric cancer (GC) cells proliferation and invasion via regulating miR-153/SNAI1 axis. (Homo sapiens) PubMed

 28139.

CircZNF609 was significantly down-regulated in colorectal cancer tissues compared with adjacent normal tissues and in the serum of patients with colorectal cancer compared with healthy controls (CircZNF609). (Homo sapiens) PubMed

 28140.

Interleukin-35 role in preserving maternal-fetal tolerance. Interleukin-35 expression in human serum and trophoblasts during pregnancy.[Interleukin-35] (Homo sapiens) PubMed

 28141.

long noncoding RNA POU3 F3, induced by transcription factor SP1, acts as an oncogene in the cervical cancer tumorigenesis via regulating miR-127-5p/FOXD1 axis.[lncRNA POU3F3] (Homo sapiens) PubMed

 28142.

circMTO1 directly interact with miR-92, and subsequently serves as a miRNA sponge to upregulate WWOX expression.[circMTO1] (Homo sapiens) PubMed

 28143.

Mitochondrial Peptide Humanin Protects Silver Nanoparticles-Induced Neurotoxicity in Human Neuroblastoma Cancer Cells. (Homo sapiens) PubMed

 28144.

hsa_circ_0079993 acts as an oncogene in colorectal cancer through the miRNA-203a-3p.1/CREB1 axis.[has_circ_0079993] (Homo sapiens) PubMed

 28145.

CA724 is not only a cancer biomarker but also a potential biomarker for patients suffering gout.[CA724] (Homo sapiens) PubMed

 28146.

he serum CA50 levels could be used as diagnostic biomarkers not only for cancers but also for other nonneoplasm diseases.[CA50] (Homo sapiens) PubMed

 28147.

CA242 might be a systemic malfunction biomarker associated with cancers and other chronic diseases.[CA242] (Homo sapiens) PubMed

 28148.

serum CA199 levels are not only increased in pancreatic and other cancer patients but also either increased or decreased in noncancer diseases.[CA199] (Homo sapiens) PubMed

 28149.

a novel mechanism of circMTO1/miR-6893 in tumorigenesis and chemoresistance of cervical cancer, is reported.[circMTO1] (Homo sapiens) PubMed

 28150.

The authors performed in depth analysis of a lncRNA located proximal to the epidermal stem cell marker integrin beta-1 (ITGB1) and transcribed in the opposite direction. They dubbed this gene Beta1-adjacent long non-coding RNA, or BLNCR, and found that its expression is regulated by p63 and AP1 transcription factors.[BLNCR] (Homo sapiens) PubMed

 28151.

MicroRNA-706 expression is down-regulated by circular RNA 4099 in liver fibrosis. [microRNA-706] (Homo sapiens) PubMed

 28152.

CircRNA HECTD1 expression correlates with higher disease risk, disease severity, inflammation, and recurrence of acute ischemic stroke.[circular RNA HECTD1] (Homo sapiens) PubMed

 28153.

we revealed the upregulation of miR-125b expression in beta-thal monocytes. Interestingly, miR-125b expression levels were negatively correlated with RBC counts, Hb and PCV values. (Homo sapiens) PubMed

 28154.

Overexpression of NOAT113026 can decrease the ability of cell migration, invasion, proliferation, and colony formation by regulating NF-kappaB/p50 and SLUG through a mechanism that involves lncRNA-mRNA interactions.[LncRNA NONHSAT113026] (Homo sapiens) PubMed

 28155.

RP11-296E3.2 and LEF1-AS1 could separately serve as potential novel diagnosis and prognostic markers for colorectal cancer metastasis.[RP11-296E3.2] (Homo sapiens) PubMed

 28156.

lncRNA N-BLR is a regulator of the epithelial-to-mesenchymal transition process in gastric cancer. siRNAs for N-BLR significantly suppressed migration and invasion of gastric adenocarcinoma. (Homo sapiens) PubMed

 28157.

DLEU2 accelerates the proliferative, migratory and invasive abilities of hepatocellular carcinoma cells via binding to EZH2.[LncRNA DLEU2] (Homo sapiens) PubMed

 28158.

Has_circ_0001649 could be used as a potential biomarker for diagnosis and prognosis in solid cancer (Has_circ_0001649). (Homo sapiens) PubMed

 28159.

These findings indicate that DQ786243 may regulate the induction and function of CD4+ Treg cells through Foxp3-miR-146a-NF-kappaB axis, implicating a novel insight into understanding the progression of oral lichen planus. [LNC DQ786243] (Homo sapiens) PubMed

 28160.

a novel circ_0005576/miR-153-3p/KIF20A axis promoting cervical cancer progression, is reported.[circ_0005576] (Homo sapiens) PubMed

 28161.

Study identified a novel lncRNA, lncAPP (lncRNA activated in PCa progression), which activates in prostate cancer (PCa) progression and is expressed in primary tumor tissues and urine samples of patients with localized or advanced PCa. Upregulation of lncAPP promoted cell migration and invasion via competitively binding miR218 to facilitate ZEB2/CDH2 expression.[lncAPP] (Homo sapiens) PubMed

 28162.

overexpression of LIPCAR promotes cell proliferation, migration, and phenotypic switch of vascular smooth muscle cells.[LIPCAR] (Homo sapiens) PubMed

 28163.

our study provided the compelling evidence that miR-1254 might inhibit the progression of Oral squamous cell carcinoma(OSCC) by partially downregulating CD36, and restoration of miR-1254 may represent an effective strategy for treating oral squamous cell carcinoma. (Homo sapiens) PubMed

 28164.

Over-expression MiR-203 played the opposite role and attenuated the effects of AB209371 over-expression. Therefore, AB209371 may down-regulate miR-203 to up-regulate Survivin, thereby promoting ovarian carcinoma (OC) cell proliferation. Our study provided novel insights into the pathogenesis of OC. (Homo sapiens) PubMed

 28165.

miR-96 could directly bind to the 3'UTR region of BCR-ABL1 to regulate fusion protein expression, thereby regulating its downstream signaling pathway activity.[BCR-ABL1] (Homo sapiens) PubMed

 28166.

The present results collectively demonstrated that miRNA1013p.1 could act as an independent biomarker for the diagnosis of SCOPD and AECOPD, and that miRNA1013p.1 facilitates COPD progression by activating the EGFR/PI3K/AKT signaling pathway. (Homo sapiens) PubMed

 28167.

These findings reveal a role of TAF1 in leukemogenesis and identify TAF1 as a potential therapeutic target for AML1-ETO -expressing leukemia.[AML1-ETO] (Homo sapiens) PubMed

 28168.

we identified a new transcript, NLUCAT1, which is strongly upregulated by hypoxia in vitro and correlated with hypoxic markers and poor prognosis in lung adenocarcinoma (Homo sapiens) PubMed

 28169.

hsa_circ_0042666 regulated laryngeal squamous cell carcinoma cell proliferation and invasion by miR-223/TGFBR3 axis.[hsa_circ_0042666] (Homo sapiens) PubMed

 28170.

Results demonstrated that lncRNAu50535 expression was upregulated in lung cancer tissues and cell lines compared with normal tissues and cells. Its knockdown decreased lung cancer cell proliferation and migration, induced G0/G1 phase arrest and promoted cell apoptosis. In addition, lncRNA u50535 may facilitate lung cancer progression by activating CCL20/CCR6/ERK signaling. [lncRNAu50535] (Homo sapiens) PubMed

 28171.

A novel lncRNA NONHSAT101069 was significantly overexpressed in breast cancer tissues and promoted epirubicin resistance, migration and invasion of breast cancer cells (Homo sapiens) PubMed

 28172.

circ_0008450 acts as an oncogene in nasopharyngeal carcinoma cells through regulating miR-577/CXCL9 signaling[circ_0008450] (Homo sapiens) PubMed

 28173.

lncRNA PTAR was proposed to promote NSCLC cell growth through sponging and inactivating miR101, which may be a possible mechanism underlying miR101 copy loss in human NSCLC. (Homo sapiens) PubMed

 28174.

BMSCs-derived exosome miR-4461 downregulated COPB2 expression and inhibited HCT116 and SW480 cells migration and invasion [Microrna-4461] (Homo sapiens) PubMed

 28175.

PDK4 could be regulated by a ceRNA mechanism which mediated by lncRNA ENST00000608794 and miR-15b-5p. ENST00000608794 derepressed expression of PDK4 through competitively binding to miR-15b-5p. [lncRNA ENST00000608794] (Homo sapiens) PubMed

 28176.

miR-512-3p is a significant regulator of tumorigenesis and drug resistance in breast cancer [miR512-3] (Homo sapiens) PubMed

 28177.

Over expression of circular RNA of vimentin in leukemia patients is associated with markedly shorter overall survival and leukemia-free survival. (Homo sapiens) PubMed

 28178.

We identified a novel long non-coding RNA within RUNX1 intron 5, transcribed from a promoter located in the region BCR3, one of the chromosomal breakpoints of RUNX1 gene (Homo sapiens) PubMed

 28179.

spermatozoa-derived circNAPEPLDiso1 physically interacts with miRNAs primarily involved in the control of cell cycle.[circNAPEPLD] (Homo sapiens) PubMed

 28180.

ASPACT acts as a negative regulator of PACT at multiple levels.[ASPACT] (Homo sapiens) PubMed

 28181.

Mirt2 overexpression exhibited anti-inflammatory properties through miR-101 suppression. Inhibition of miR-101 by Mirt2 resulted in the blockage of MAPK and NF-kappaB cascades which might be a significant implication in Parkinson's Disease treatment. [Myocardial infraction associated transcript 2, Mirt2] (Homo sapiens) PubMed

 28182.

Circ_0058063 acted as a sponge of miR-145-5p to promote bladder cancer progression by up-regulating CDK6 expression. (Homo sapiens) PubMed

 28183.

The aim was to establish the reference intervals and document the differences in serum-cortisol and serum-CBG in one group of women using and another group not using ethinyl estradiol.[CBG] (Homo sapiens) PubMed

 28184.

Knock-down experiments revealed that lncRNA-CCL2 positively regulated CCL2 mRNA levels in multiple primary endothelial cells (ECs) and endothelial cells (ECs) cell lines (Homo sapiens) PubMed

 28185.

PAPAS was upregulated in tumour tissues of patients with TNBC versus tumour-adjacent healthy tissues[LncRNA PAPAS] (Homo sapiens) PubMed

 28186.

CircRNA-104718 functions as a competing endogenous RNA, targeting the miR-218-5p/TXNDC5 signaling pathway to promote hepatocellular carcinoma progression. (Homo sapiens) PubMed

 28187.

TNF-alpha-induced lncRNA LOC105374902 may function as a ceRNA for miR-1285-3p to promote the expression of RPL14, promoting the migration, invasion of cervical cancer cells. [miR-1285-3] (Homo sapiens) PubMed

 28188.

These findings indicated that long non-coding RNA AV310809 promoted TGF-beta1-induced epithelial-mesenchymal transition in human peritoneal mesothelial cells through the activation of the Wnt2/beta-catenin signaling pathway, possibly by targeting beta-catenin. [long non-coding RNA AV310809] (Homo sapiens) PubMed

 28189.

the current study not only establishes a novel regulatory axis of miR-3687/FOXP1 regarding regulation of cyclin E2 expression in bladder cancer (BC) cells, but also provides strong suggestive evidence that miR-3687 and FOXP1 may be promising targets in therapeutic strategies for human BC. (Homo sapiens) PubMed

 28190.

Our study is the first to document the pro-bone metastatic role of Lnc34a in BM of HCC and reveal a novel mechanism for the activation of the TGF-beta signaling pathway in HCC BM, providing evidence of a potential therapeutic strategy in HCC BM. (Homo sapiens) PubMed

 28191.

Long noncoding RNA lncAKHE cooperated with YEATS4 to enhance the activation of NOTCH2 signaling in hepatocellular carcinoma, promoting tumor cell growth and migration. (Homo sapiens) PubMed

 28192.

miR-24-3p inhibited the osteogenic differentiation of periodontal ligament stem cells through SMAD5. (Homo sapiens) PubMed

 28193.

hsa-miR-12528 can regulate tumourigenesis and metastasis of non-small cell lung carcinoma cells through hypo-phosphorylation of AKT cascade by targeting IGF-1R. (Homo sapiens) PubMed

 28194.

novel finding that targeting ChABC to the axon significantly enhances its ability to promote neurite extension, suggests that this may be an effective way of promoting long-distance axon regeneration following spinal cord injury. It could also potentially improve its efficacy in the treatment of other pathologies, where it has been shown to promote recovery, such as myocardial infarction, stroke and Parkinson's disease (Homo sapiens) PubMed

 28195.

Human evolutionary loss of CMAH likely contributes to atherosclerosis predisposition via multiple intrinsic and extrinsic mechanisms.[CMAH] (Homo sapiens) PubMed

 28196.

the present results suggested that miR1385p may be a tumor suppressor in NSCLC cells and a promising therapeutic target for treating patients with NSCLC. (Homo sapiens) PubMed

 28197.

the present results indicated that circFAM53B could be a competing endogenous RNA (ceRNA) to competitively sponge miR646 and miR647 to upregulate VAMP2 and MDM2 expression at the posttranscriptional level, thus mediating the cellular behaviors of Ovarian cancer cells (Homo sapiens) PubMed

 28198.

our study indicates that differentially expressed circRNAs are closely related to the carcinogenesis of oral squamous cell carcinoma (OSCC). Among these, circRNA_102459 and circRNA_043621 may function as a tumorsuppressor and promoter, respectively, of OSCC carcinogenesis, and thus may be valuable diagnostic biomarkers of OSCC (Homo sapiens) PubMed

 28199.

our data suggest that LINC00673-v4 is a driver molecule for metastasis via constitutively activating WNT/beta-catenin signaling in ung adenocarcinoma (LAD) and may represent a potential therapeutic target against the metastasis of LAD (Homo sapiens) PubMed

 28200.

Downregulation of circDNMT3B contributes to vascular dysfunction in diabetic retinas through regulating miR-20b-5p and BAMBI, providing a potential treatment strategy for diabetic retinopathy[circRNA DNMT3B] (Homo sapiens) PubMed

 28201.

hsa_circ_0005962 was upregulated in lung adenocarcinoma plasma and cells, whereas hsa_circ_0086414 was downregulated.[hsa_circ_0005962, has_circ_0086414] (Homo sapiens) PubMed

 28202.

BerEP4 expression can help in distinction of these tumors in cases of basal cell carcinomas with extensive squamatization[ BerEP4 ] (Homo sapiens) PubMed

 28203.

Blnc1 forms a ribonucleoprotein complex with transcription factor EBF2 to stimulate the thermogenic gene program. Further, Blnc1 itself is a target of EBF2 forming a feedforward regulatory loop to drive adipogenesis toward thermogenic phenotype. [Blnc1] (Homo sapiens) PubMed

 28204.

lncEGFL7OS is required for MAPK and AKT pathway activation by regulating EGFL7/miR-126 expression.[LncEGFL70S] (Homo sapiens) PubMed

 28205.

our study identifies lncRNA-MM2P as a modulator required for macrophage M2 polarization and uncovers its role in macrophage-promoted tumorigenesis. (Homo sapiens) PubMed

 28206.

circ_0067934 promotes cervical cancer progression via miR-545/EIF3C axis.circ_0067934] (Homo sapiens) PubMed

 28207.

HnRNP E1 is a new regulator of Vascular endothelial cell apoptosis and autophagy through mediating HMBOX1 expression. (Homo sapiens) PubMed

 28208.

miR-9-5p directly targeted the 3'-UTR of PAK4 mRNA and negatively regulated its expression. [miR-9-5p] (Homo sapiens) PubMed

 28209.

The novel microRNA hsa-miR-CHA1 regulates cell proliferation and apoptosis in human lung cancer by targeting XIAP. [mir-CHA1] (Homo sapiens) PubMed

 28210.

The regulation of mitochondrial open reading frame of 12S rRNA-c (MOTS-c) and humanin in patients with chronic kidney failure is reported.[MOTS-c; humanin] (Homo sapiens) PubMed

 28211.

the scaffold protein 14-3-3theta; enhances the aberrant activity of the chimeric transcription factor MLL-AF4 and, therefore, represents a new player in the molecular pathogenesis of t(4;11)-positive leukemia.[MLL-AF4] (Homo sapiens) PubMed

 28212.

The disruption of the FA-SAT non-coding RNA/PKM2 protein complex, by the depletion of either FA-SAT or PKM2, results in the same phenotype-apoptosis, and the ectopic overexpression of FA-SAT did not affect the cell-cycle progression, but promotes the PKM2 nuclear accumulation.[FA-SAT] (Homo sapiens) PubMed

 28213.

long noncoding RNA CTA-941F9.9 is frequently downregulated in colorectal cancer.[lncRNA CTA-941F9.9] (Homo sapiens) PubMed

 28214.

Over expression of lncRNA NeST is detected in the early stages of prostate cancer and correlates with poor prognosis. (Homo sapiens) PubMed

 28215.

Our study demonstrates that lncRNA-HGBC promotes GBC metastasis via activation of the miR-502-3p-SET-AKT cascade, pointing to lncRNA-HGBC as a new prognostic predictor and a therapeutic target. (Homo sapiens) PubMed

 28216.

hsa_circ_101882 is considered a metastasis promoter by activating epithelial-to-mesenchymal transition and may serve as a critical oncogene and potential new biomarker in Gastric cancer.[Has_circ_101882] (Homo sapiens) PubMed

 28217.

This study reveals that miR-29b-3p functions as a novel regulator of cardiac development and inhibits cardiomyocyte proliferation via NOTCH2, which provides novel insights into the aetiology and potential treatment of congenital heart disease. [miR-29b-3p] (Homo sapiens) PubMed

 28218.

enhanced WiNTRLINC1/ASCL2/c-Myc axis involved in Wnt pathway activation is a common pathway essential for differentiated colon tumorigenesis, especially with young onset, and may be essential for a viable phenotype of colon cancer[WiNTRLINC1] (Homo sapiens) PubMed

 28219.

These results showed that both hsa_circ_0067582 and hsa_circ_0005758 may play an important role in gastric carcinogenesis.[hsa_circ_0067582 and hsa_circ_0005758] (Homo sapiens) PubMed

 28220.

Long noncoding RNA HERES (highly expressed lncRNA in esophageal squamous cell carcinoma) appears to be a transacting factor that regulates CACNA2D3, SFRP2, and CXXC4 simultaneously to activate Wnt signaling pathways in esophageal squamous cell carcinoma through an interaction with EZH2 via its G-quadruple structure-like motif.[lncRNA HERES] (Homo sapiens) PubMed

 28221.

This study identified ADAMTS9, FKBP5, and PFKBF3 were identified as valuable methylation-based biomarkers for osteoarthritis.[PFKBF3] (Homo sapiens) PubMed

 28222.

lncRNA KHPS1 binding to a triplex-forming region upstream of the SPHK1 promoter activates a poised enhancer. (Homo sapiens) PubMed

 28223.

Circulating miR-338-3p and miR-199b-5p are correlated to the neutrophil count in the blood of resectable pancreatic cancer patients, suggesting a potential role of circulating miRNAs in cancer immune evasion and systemic inflammation [miR-199b-5p] (Homo sapiens) PubMed

 28224.

Since cancer stem cells (CSCs) are radioresistant and metastasis-initiating cells, we examined TGLI1 for its involvement in breast CSCs and found TGLI1 to transcriptionally activate stemness genes CD44, Nanog, Sox2, and OCT4 leading to CSC renewal, and TGLI1 outcompetes with GLI1 for binding to target promoters. (Homo sapiens) PubMed

 28225.

the novel direct interaction between PODXL1 and the C5aR/C5a axis may provide a better integrated understanding of PDAC biological characteristics including its tumor microenvironment factors. (Homo sapiens) PubMed

 28226.

Circ-U2AF1 promotes glioma malignancy by derepressing neuro-oncological ventral antigen 2 expression by sponging hsa-miR-7-5p. (Homo sapiens) PubMed

 28227.

Knockdown of long non-coding RNA LOC100133669 inhibited oesophageal squamous cell carcinoma cell proliferation and cell cycle progression, while overexpression of LOC100133669 showed the opposite effects. [Long non-coding RNA LOC100133669] (Homo sapiens) PubMed

 28228.

LncRNA-CDC6 could function as ceRNA to target CDC6 expression by sponging microRNA-215 and promote the proliferation and metastasis of breast cancer cells. (Homo sapiens) PubMed

 28229.

hsa_circ_0055538 is involved in Oral squamous cell carcinoma via the p53 signaling pathway.[hsa_circ_0055538] (Homo sapiens) PubMed

 28230.

LncRNAENST00000453774.1 (LncRNA 74.1) promoted reactive oxygen species defense by activating prosurvival autophagy then decreased ECM-related proteins fibronectin and collagen I involved in renal fibrosis. (Homo sapiens) PubMed

 28231.

our study demonstrated that the expression of plasma hsa_circ_0064428 is negatively associated with tumour TILs level and survival in patients with HCC, which make it a promising non-invasive prognosis biomarker. (Homo sapiens) PubMed

 28232.

The reduction in serum level of CYFRA21-1 or CEA might be a reliable biomarker to predict immunotherapy efficacy in non-small cell lung cancer patients. NSE was not significant for monitoring the efficacy of nivolumab.[CYFRA21-1, CEA] (Homo sapiens) PubMed

 28233.

circBACH2 could directly bind to miR-139-5p and relieve suppression of the target LMO4; inhibiting circBACH2 expression decreased cell proliferation, migration, and invasion. Finally, down-regulating circBACH2 suppressed the growth of papillary thyroid carcinoma xenografts in nude mice (circBACH2). (Homo sapiens) PubMed

 28234.

circHIPK3 is upregulated in bleomycin-induced pulmonary fibrosis mice model, fibroblast-to-myofibroblast transition (FMT)-derived myofibroblasts. circHIPK3 silencing can ameliorate FMT and suppress fibroblast proliferation in vivo and vitro. Fundamentally, circHIPK3 regulates FMT by functioning as an endogenous miR-338-3p sponge and inhibit miR-338-3p activity, thereby leading to increased SOX4 and COL1A1 expression. (Homo sapiens) PubMed

 28235.

The cation-chloride cotransporter KCC1 adopts an inward-facing conformation, with the extracellular gate occluded. KCC1 exists as a dimer, with both extracellular and transmembrane domains involved in dimerization. [KCC1] (Homo sapiens) PubMed

 28236.

NEF overexpression inhibited the migration and invasion of HPV-negative but not HPV-positive cervical squamous cell carcinoma (CSCC) cells. NEF overexpression down-regulated TGF-b1 in HPV-negative CSCC cells but not in HPV-positive CSCC cells (Homo sapiens) PubMed

 28237.

logistic regression model showed that the combination of hsa_circ_0002715 and hsa_circ_0035197 could provide the best diagnostic accuracy with an area under the curve (AUC) of 0.758 (sensitivity: 72.9%, specificity: 71.4%)[Hsa_circ_0002715 and Hsa_circ_0035197] (Homo sapiens) PubMed

 28238.

Retinoblastoma progression was suppressed by overexpression of miR-129-5p which directly targets expression of PAX6 through PI3K/AKT signaling pathway, to reduce proliferation, migration and invasion of retinoblastoma cells. (Homo sapiens) PubMed

 28239.

low expression of LINC00467 is associated with the incidence and progression of HCC and highlighted the critical role of the LINC00467/miR-9-5a/PPARA signalling axis in this disease. (Homo sapiens) PubMed

 28240.

Our research proposes a novel mechanism where the role of MALAT1 is dependent on the MALAT1/miR-181a-5p/AKT3 axis. MALAT1 competes with AKT3 for miR-181a-5p binding, thereby upregulating the AKT3 protein level and ultimately promoting the growth of gastric adenocarcinoma. (Homo sapiens) PubMed

 28241.

rs60452575 variant influences KCNJ11 expression and sulfonylurea response [MIR4532] (Homo sapiens) PubMed

 28242.

Overall survival (OS) analysis revealed that high miR-92a-3p expression predicts significantly prolonged OS of CLL patients. (Homo sapiens) PubMed

 28243.

Study identifies SWINGN, a lncRNA interacting with SMARCB1 exclusively in proliferating conditions, exerting a pro-oncogenic role in some tumor types. SWINGN is transcribed from an enhancer and modulates the activation of GAS6 oncogene as part of a topologically organized region, as well as a larger network of pro-oncogenic genes by favoring SMARCB1 binding. [lncRNA SWINGN] (Homo sapiens) PubMed

 28244.

interference of LINC00483 weakens its competitive binding ability to miR-144, thus reducing HOXA10 expression, and enhancing radiosensitivity in lung adenocarcinoma.[LINC00483] (Homo sapiens) PubMed

 28245.

comparison of the expression level of MDR1 and multidrug-resistance protein A genes in acute, chronic non-lupoid, and chronic lupoid forms of dry cutaneous leishmaniasis (multidrug-resistance protein A). (Homo sapiens) PubMed

 28246.

Circular RNA circHIPK3 may serve as a prognostic marker to promote chronic myeloid leukemia (CML) progression. Circular RNA circHIPK3 was significantly upregulated in peripheral blood mononuclear cells and serum samples from patients with CML (Circular RNA circHIPK3). (Homo sapiens) PubMed

 28247.

A novel miRNA named MIR-G-1 by GRSF1-RNA immunoprecipitation (RIP)-deep sequencing could directly target and upregulate LMNB1 and TMED5 in a GRSF1-dependent manner in cervical cancer cells. In addition, upregulated MIR-G-1 in cervical cancer promoted a malignant phenotype in vitro and in vivo. (Homo sapiens) PubMed

 28248.

AID-catalyzed deamination during Pol II transcription elongation in conjunction with DSIF transcription factor, is reported.[RNA polymerase II] (Homo sapiens) PubMed

 28249.

our data identified GAS6-AS2 as an oncogenic lncRNA in melanoma via activation of GAS6/AXL/AKT/ERK signals. Our data suggested that GAS6-AS2 may be a novel potential prognostic biomarker and therapeutic target for melanoma (Homo sapiens) PubMed

 28250.

lncRNA XLOC_001659 knockdown inhibits proliferation and invasion of esophageal squamous cell carcinoma cells via regulation of miR-490-5p/PIK3CA, suggesting that it may play a role in ESCC tumorigenesis and progression [lncRNA XLOC_001659] (Homo sapiens) PubMed

 28251.

circ-0000284 can be directly transferred from cholangiocarcinoma cells to surrounding normal cells via exosomes and in this way regulate the biological functions of surrounding normal cells.[Circ-0000284] (Homo sapiens) PubMed

 28252.

present electrophysiological evidence that TPC3 voltage activation depends only on voltage sensing domain 2 [tpc3] (Homo sapiens) PubMed

 28253.

Thus SENEBLOC drives both p53-dependent and p53-independent mechanisms that contribute to p21 repression. (Homo sapiens) PubMed

 28254.

pseudogene RP11-564D11.3 was frequently upregulated and associated with poor prognosis in hepatocellular carcinoma. (Homo sapiens) PubMed

 28255.

loss of circRNA_0084043 depressed HG-induced damage via sponging miR-140-3p and regulating TGFA. (Homo sapiens) PubMed

 28256.

miR-646 acted as a target of hsa_circ_0041795 and VEGFC was a direct target of miR-646.[hsa_circ_0041795] (Homo sapiens) PubMed

 28257.

Lnc-GIHCG increases cell proliferation and migration in gastric cancer through miR- 1281 adsorption. (Homo sapiens) PubMed

 28258.

MAGI2-AS3/miR-374b-5p/SMG1 axis that suppresses hepatocellular cancer progression, is reported. (Homo sapiens) PubMed

 28259.

we identified a novel lncRNA OXCT1-AS1 and investigated its role and potential mechanisms in bladder cancer. OXCT1-AS1 inhibited miR-455-5p to decrease its binding to the JAK1 3'-untranslated region, which could upregulate the expression of JAK1 at the protein level, thus promoting bladder cancer proliferation and invasion (Homo sapiens) PubMed

 28260.

In hepatocellular carcinoma cells hsa_circ_0091570 sponges miR-1307 and regulates ISM1 expression to suppress tumor progression. (Homo sapiens) PubMed

 28261.

(IL-35) Serum IL-35 levels were significantly higher in patients with rheumatoid arthritis. (Homo sapiens) PubMed

 28262.

Knockdown of hsa_circ_0118530 repressed polycystic ovary syndrome progression via sponging miR-136 (hsa_circ_0118530). (Homo sapiens) PubMed

 28263.

circRNA_100290 serves as a ceRNA to counteract miR-378a-mediated GLUT1 suppression, thus promoting glycolysis and cell proliferation in oral squamous cell carcinoma (OSCC). (Homo sapiens) PubMed

 28264.

LOC389332 was potential non-coding oncogenes in gastric cancer.[LOC389332] (Homo sapiens) PubMed

 28265.

hsa_circ_0035483 promotes autophagy and tumor growth and enhances gemcitabine resistance in renal cancer cells by regulating hsa-miR-335/CCNB1.[has_circ_0035483] (Homo sapiens) PubMed

 28266.

tudy confirmed that the circ_0001946/miR-671-5p/ CDR1 pathway modulates the development of glioblastoma (Homo sapiens) PubMed

 28267.

A novel lncRNA named Nrf2-activating lncRNA is transcribed from an upstream region of the microRNA 122 gene. It was a ceRNA for Plk 2 and p21(cip1) through binding of miRNA 128 and miRNA 224, inducing Plk2/Nrf2/p21(cip1) complexation for Nrf2 activation in the cells under p53-activating conditions. Its levels correlate with liver cancer survival. It is a fine-tuning rheostat for cell fate decision. Nrf-lncRNA. (Homo sapiens) PubMed

 28268.

We showed that miR-8075 that was downregulated in cervical cancer tissues repressed cervical cancer cell proliferation, migration, and invasion. Furthermore, we validated that upregulation of TPX2 by hsa_circRNA_101996-mediated inhibition of miR-8075 contributed to cervical cancer proliferation, migration, and invasion (Homo sapiens) PubMed

 28269.

CircNR3C1 possesses four targeting sites of miR-27a-3p and could effectively sponge miR-27a-3p to suppress the expression of cyclin D1, inhibiting the proliferation of bladder cancer cells. (Homo sapiens) PubMed

 28270.

miR-181b expression was related to the development of diabetic nephropathy via targeting TIMP3. [MIRN181b] (Homo sapiens) PubMed

 28271.

MIR24-3 Salivary exosomal miR-24-3p is a potential novel diagnostic biomarker for oral squamous cell carcinoma (OSCC) screening, and miR-24-3p can maintain the proliferation of OSCC cells (Homo sapiens) PubMed

 28272.

The lncRNA DAPK1-IT1 upregulates lipoprotein lipase (LPL) via regulating hsa-miR-590-3p. [lncRNA DAPK1-IT1] (Homo sapiens) PubMed

 28273.

All the data in the present study revealed that the downregulated expression of miR-519a predicts the poor prognosis of GC and is involved in the regulation of GC progression. We consider that miR-519a may be a candidate therapeutic target for GC treatment. (Homo sapiens) PubMed

 28274.

The newly identified lncIRS1 acts as a sponge for miR-15 family to regulate IRS1 expression, resulting in promoting skeletal muscle myogenesis and controlling atrophy. (Homo sapiens) PubMed

 28275.

the in vivo experiments further identified the antitumor effects of inhibiting LINRIS in CRC, and the analysis of LINRIS/IGF2BP2 expression in the tissues from patients indicated their unique role in the development of CRC. (Homo sapiens) PubMed

 28276.

circFNC3B increased CD44 expression, which was associated with cell adhesion, via the formation of a ternary complex of circFNDC3B-IGF2BP3-CD44 mRNA.[circFNC3B] (Homo sapiens) PubMed

 28277.

ur study identified a novel lncRNA associated with poor prognosis in lung cancer. LCAT1 is an oncogenic regulator that promotes cell proliferation and metastasis (Homo sapiens) PubMed

 28278.

the ectopic expression of circ_0003204 inhibited proliferation, migration and tube formation of HAECs exposed to ox-LDL. Mechanically, circ_0003204 could promote protein expression of TGFbetaR2 and its downstream phosph-SMAD3 through sponging miR-370, and miR-370 targeted the 3' untranslated region (UTR) of TGFbetaR2. (Homo sapiens) PubMed

 28279.

The miRNA miR-194-5p targeted MALAT1 for degradation in the nucleus in an Ago2-dependent manner; the rs664589 G allele altered the binding of MALAT1 to miR-194-5p, resulting in increased expression of MALAT1. MALAT1 with the rs664589 G allele demonstrates altered binding to miR-194-5p in the nucleus, leading to increased MALAT1 expression and enhanced colorectal cancer development. miR-194-5. (Homo sapiens) PubMed

 28280.

circ_000173 promoted growth and invasion in glioblastoma cells via the miR-326/Wnt7B axis[circ_0001730] (Homo sapiens) PubMed

 28281.

Our study reveals that H19, but not MALAT1 and GAS5, may be a useful marker of response to neoadjuvant chemotherapy in breast cancer. (Homo sapiens) PubMed

 28282.

circMAN2B2 could improve cell proliferation, invasion, and migration of the glioma by inhibiting miR-1205 and promoting the expression of S100A8. (Homo sapiens) PubMed

 28283.

A significant inverse correlation was observed between miR-129-5p and HMBG1 protein levels in the 102 serum samples from chronic heart failure patients.[miR-129-5p] (Homo sapiens) PubMed

 28284.

long noncoding RNA AC073284.4 might serve as a competing endogenous RNA (ceRNA) in breast cancer progression via modulating miR-18b-5p/DOCK4 axis (Homo sapiens) PubMed

 28285.

This study demonstrated that overexpression of TAZ caused by downregulation of miR-125b promoted resistance of glioma cells to TRAIL. MiR-125b/TAZ axis may represent a potential strategy to reverse the TRAIL in glioma.[mir-125b] (Homo sapiens) PubMed

 28286.

lncRNA LCTS5, The newly identified lncRNA LCTS5 impairs non-small cell lung cancer progression; LCTS5 interacts with INO80 to reduce INO80 occupancy at enhancer regions of multiple lung cancer related genes without affecting INO80 decay. (Homo sapiens) PubMed

 28287.

LINC00958 could regulate RRM2 by competing to miR-5095, which regulates cell sensitivity to radiotherapy in cervical cancer[microRNA-5095] (Homo sapiens) PubMed

 28288.

Serum reference intervals for gastrointestinal tumor biomarkers CA199 and CA724 in the healthy adults of Han nationality.[CA199] [CA724] (Homo sapiens) PubMed

 28289.

The measurement of serum anti-3'-sialyllactose antibodies could play a supportive role in diagnostics and complement the performance of CA19-9 for the early detection of pancreatic ductal adenocarcinoma. (Homo sapiens) PubMed

 28290.

For the first time we analyzed Apo10 and TKLT1 in patients with cholangiocellular (CCC), pancreatic (PC), and colorectal carcinoma (CRC). (Homo sapiens) PubMed

 28291.

LncRNAs encoded by AC007278.2 and IFNG-AS1-001 showed significantly higher expression in relapsing Phase multiple sclerosis patients whereas IFNG-AS1-003 was elevated in patients in the remitting phase compared with relapsing patients.[AC007278.2] (Homo sapiens) PubMed

 28292.

Our data provide evidence that circ_0005705 promotes the hepatocellular carcinoma progression by sponging miR-335 and further regulating MAPK1 expression.[Circ_0005075] (Homo sapiens) PubMed

 28293.

CKD1 expression in the colorectal cancer is regulated by PSME3.[CKD1] (Homo sapiens) PubMed

 28294.

GPX3-AS downregulated the apoptosis of lens epithelial cells via promoting GPX3 expression.[GPX3-AS] (Homo sapiens) PubMed

 28295.

Overexpression of circCASC15 was closely associated with bladder cancer (BC) tumor stage and promoted cell proliferation significantly in vitro and in vivo. Mechanistically, circCASC15 could act as miR-1224-5p sponge to activate the expression of CREB1 to promote cell proliferation in BC. (circCASC15) (Homo sapiens) PubMed

 28296.

The findings obtained in the present study indicate that TTN-AS1 facilitated PTC progression by regulating the miR-153-3p/ZNRF2 axis and activating the PI3K/Akt/mTOR pathway. (Homo sapiens) PubMed

 28297.

Cell hypoxia increases TR4, which plays a critical role in regulating renal cell carcinoma (RCC) resistance to sunitinib through transcriptional regulation of lncTASR (ENST00000600671.1) which might then increase AXL protein expression via enhancing the stability of AXL mRNA to increase the sunitinib resistance.[long-noncoding RNA lncTASR] (Homo sapiens) PubMed

 28298.

Clinically, XLOC_006390 was positively correlated with the mRNA level of GDH1, and c-Myc positively regulated GDH1 gene expression, which was tightly associated with PC patient prognosis. The dysregulated lncRNA/c-Myc axis increased glutamate metabolism, promoting PC progression to a higher stage. (Homo sapiens) PubMed

 28299.

High expression of circ_0000502 was significantly positively correlated with poor prognosis of hepatocellular carcinoma[circ_0000502] (Homo sapiens) PubMed

 28300.

Disruption of a lncRNA gene (ASAR6-141) results in delayed replication timing in cis (ASAR6-141). (Homo sapiens) PubMed

 28301.

Mechanistically, LncRNA AWPPH was demonstrated to sponge miR-93-3p and promote FZD7 expression, causing activation of Wnt/beta-catenin. [LncRNA AWPPH] (Homo sapiens) PubMed

 28302.

CD44 regulates PES1 in liver cancer stem cells via miR-105-5p to promote cell growth [MiR-105] (Homo sapiens) PubMed

 28303.

inhibition of miR-4532 protects human lens epithelial cells from ultraviolet radiation-induced oxidative injury via activation of SIRT6-Nrf2 pathway.[miR4532] (Homo sapiens) PubMed

 28304.

STRO-1 may be a useful marker to isolate undifferentiated (potent) mesenchymal cells from gingiva.[STRO-1] (Homo sapiens) PubMed

 28305.

LNRRIL6 may be a potential prognostic biomarker and therapeutic target for colorectal cancer.[LNRRIL6] (Homo sapiens) PubMed

 28306.

The expression level of CAMK2D-associated transcript 1 (C2dat1) was higher in coronary artery disease tissues than in normal arterial tissues and in the proliferating vascular smooth muscle cells (VSMC) after treatment with PDGF-bb or TNF-alpha. Its overexpression promoted VSMC growth, enhanced PCNA expression and increased VSMC migration. [C2dat1] (Homo sapiens) PubMed

 28307.

circ-ZNF652 is a novel driver of EMT and unveil the important regulatory role of circ-ZNF652/miR-203/miR-502-5p/Snail feedback loop in hepatocellular carcinoma metastasis.[circ-ZNF652] (Homo sapiens) PubMed

 28308.

MNX1-AS1 promoted COMMD8 expression through sponging miR-218-5p. MNX1-AS1 promoted hepatocellular carcinoma progression through activating COMMD8. [miR-218-5p] (Homo sapiens) PubMed

 28309.

Up-regulation of FLJ37505 significantly inhibits the proliferation and migration of bladder cell carcinoma[FLJ37505] (Homo sapiens) PubMed

 28310.

Results revealed that upregulated circ-0000745 in acute lymphoblastic leukemia cells could promoter cell viability by increasing the activation of ERK pathway (circ-0000745). (Homo sapiens) PubMed

 28311.

there is a novel positive regulatory feedback loop between XTP8 and FOXM1 promoting the development of Hepatocellular carcinoma.[XTP8] (Homo sapiens) PubMed

 28312.

the pepsinogen I/II ratio was the most reliable gastric mucosal-change biomarker.[Pepsinogen I] (Homo sapiens) PubMed

 28313.

Zfp281 is a conserved factor for the maintenance of trophoblast stem cell plasticity.[Zfp281] (Homo sapiens) PubMed

 28314.

Knockdown of linc00152 inhibited gastric cancer progression by sequestering miR-193b-3p from ETS1 in vitro and in vivo[linc00152] (Homo sapiens) PubMed

 28315.

hsa_circ0021347 was selected and validated to be significantly downregulated in OS tissues and cell lines and showed a strong negative relationship with B7-H3 expression in OS. In addition, clinicopathological features showed that hsa_circ0021347 in OS tissues was negatively associated with Enneking stage and positively associated with patients' survival (Homo sapiens) PubMed

 28316.

lncRNA-PDPK2P interacted with PDK1 and promoted hepatocellular carcinoma progression through the PDK1/AKT/caspase 3 signaling pathway. [lncRNA-PDPK2P] (Homo sapiens) PubMed

 28317.

LINC00313 is upregulated in osteosarcoma (OS), and LINC00313 knockdown plays a vital anti-tumor role in OS cell progression through a miR-342-3p/FOSL2 axis.[LINC00310] (Homo sapiens) PubMed

 28318.

these data displayed the crucial role of circRAD23B/miR-5095 regulating PARP2 and AKT2 in esophageal cancer.[circRAD23B, miR5095] (Homo sapiens) PubMed

 28319.

a novel tumor suppressive long noncoding RNA TSLD8 which exerts its tumor suppressive function by stabilizing WWOX, is reported.[lncRNA TSLD8] (Homo sapiens) PubMed

 28320.

circRNA_0016624 could sponge miR-98 and enhance BMP2 expression.[circRNA_0016624] (Homo sapiens) PubMed

 28321.

lncRNA RP5-837J1.2 gene expression in blood and ovarian cancer.[lncRNA RP5-837J1.2] (Homo sapiens) PubMed

 28322.

LINC81507 is decreased in non-small cell lung cancer and functions as a sponge to miR-199b-5p to regulate CAV1/STAT3 pathway. (Homo sapiens) PubMed

 28323.

LncRNA snaR was up-regulated in triple-negative breast cancer tissues and was inversely correlated with NRON. . NRON overexpression inhibited cancer cell proliferation and down-regulated snaR. The snaR overexpression reduced the effects of NRON overexpression. [LncRNA snaR] (Homo sapiens) PubMed

 28324.

LncRNA IUR can downregulate ZEB1 by upregulating miR-200 to inhibit prostate carcinoma cell invasion and migration. (Homo sapiens) PubMed

 28325.

Overexpression of lncRNA DILC resulted in promoted apoptosis of HFLS isolated from RA patients, while lncRNA DILC siRNA silencing played an opposite role. In addition, overexpression of lncRNA DILC also resulted in inhibited IL-6 expression in HFLS isolated from RA patients. (Homo sapiens) PubMed

 28326.

Overexpression of lncRNA CASC2 led to up-regulated expression of IL-17 in cells of human chondrocyte cell line CHON-001 (ATCC((R)) CRL-2846trade mark). In addition, overexpression of lncRNA CASC2 inhibited the proliferation, and promoted the apoptosis of chondrocyte. [lncRNA CASC2] (Homo sapiens) PubMed

 28327.

The over expression of miR-19a was an underlying risk of poor prognosis in many human malignancies, especially in osteosarcoma. [miR-19a] (Homo sapiens) PubMed

 28328.

results indicate that the association of PUR proteins with circSamd4 enhances myogenesis by contributing to the derepression of MHC transcription (circSamd4). (Homo sapiens) PubMed

 28329.

This study revealed that circVAPA contributes to Hepatocellular carcinoma (HCC) cell proliferation through sponging miR-377-3p and thereby disinhibiting prosaposin (PSAP), shedding light on a new insight into HCC initiation and progression (Homo sapiens) PubMed

 28330.

A novel lncRNA, n384546 has been identified, which is highly expressed in papillary thyroid carcinoma (PTC) tissues and cell lines. n384546 expression was associated with clinicopathological features of PTC patients, such as tumor size, lymph node metastasis, and TNM stage. (Homo sapiens) PubMed

 28331.

miR-153-3p can inhibit the proliferation, migration and invasion of breast cancer cells via down-regulation of ROCK1 [miR153-3] (Homo sapiens) PubMed

 28332.

The authors data show that PGA2 induces Nur77 transcriptional activity by forming a covalent adduct between its endocyclic beta-carbon, C9, and Cys566 in the receptor's ligand-binding domain. (Homo sapiens) PubMed

 28333.

mirn294 has a role in cell proliferation, migration and invasion of invasion of human hepatoma cells through the JNK/ERK pathway [miR-294] (Homo sapiens) PubMed

 28334.

serum preptin concentrations are associated with renal function and diabetic nephropathy.[Preptin] (Homo sapiens) PubMed

 28335.

l-adrenaline inhibits caspase-11 inflammasome activation through the ADRA2B receptor and the intracellular cAMP metabolism pathway in mouse macrophages or human monocytes [caspase 11] (Homo sapiens) PubMed

 28336.

reveal that DUXAP9-206 induced non-small cell lung cancer cell proliferation and metastasis (Homo sapiens) PubMed

 28337.

LncRNA BX357664 in non-small cell lung cancer (NSCLC) was remarkably lower than that in normal tissues and its downregulation was associated with advanced tumor stage, higher incidence of lymph node or distant metastases and lower overall survival rate. BX357664 may inhibit the proliferation as well as invasion and migration of NSCLC cells by regulating TGF-beta1/Smad pathway.[LncRNA BX357664] (Homo sapiens) PubMed

 28338.

Long non-coding RNA TUBA4B was largely downregulated in breast cancer samples and cell lines. The functional analysis demonstrated that breast cancer cells proliferation and invasion could be inhibited by overexpression of TUBA4B. The results of Luciferase reporter assays indicated that TUBA4B directly targeted miR-19, which could rescue the effects of TUBA4B on breast cancer cells (Long non-coding RNA TUBA4B). (Homo sapiens) PubMed

 28339.

Study describes molecular mechanism by which type 1 diabetes (T1D)-associated lncRNA Lnc13 regulates virus-induced pancreatic beta-cell inflammation. Lnc13 acts as a linker between the RNA binding protein PCBP2 and the 3'UTR of STAT1 to stabilize the mRNA of STAT1. This stabilization leads to increased activation of the STAT1 proinflammatory pathway, contributing to local inflammation and eventual beta-cell dest...[Lnc13] (Homo sapiens) PubMed

 28340.

Periostin is not useful for assessing Paget's disease of bone, whilst TRAP5b, which has been a scarcely explored bone turnover marker until now, may be useful in the analysis of this disease.[Trap5b] (Homo sapiens) PubMed

 28341.

the downregulation of lnRNA-NEF may contribute to the postoperative distant recurrence in patients with prostate cancer through the interactions with TGF-beta1.[lnRNA-NEF] (Homo sapiens) PubMed

 28342.

The oncogenic role of circ_0008450 was partially attributed to its suppression on miR-548p.[circ_0008450] (Homo sapiens) PubMed

 28343.

Our results revealed that circHECTD1 is a glutaminolysis-associated circRNA that promotes gastric cancer (GC) progression. The circHECTD1/miR-1256/USP5 axis could thus be used as a therapeutic target for GC. (Homo sapiens) PubMed

 28344.

circPRKCI promotes human glioma cell progression possibly by inhibiting miR-545.[circPRKCI] (Homo sapiens) PubMed

 28345.

Expression of TFG-RET leads to the upregulation of HUWE1 and inhibition of HUWE1 significantly reduces RET-mediated oncogenesis.[TFG-RET] (Homo sapiens) PubMed

 28346.

The lncRNA-FA2H-2-MLKL pathway is essential for regulation of autophagy and inflammation, and suggested that lncRNA-FA2H-2 and MLKL could act as potential therapeutic targets to ameliorate atherosclerosis-related diseases.( lncRNA-FA2H-2 ) (Homo sapiens) PubMed

 28347.

Overexpression of IL22RA1 enhanced HTFs migration and proliferation, while miR-760 and miR-215-3p mimics reversed these promotive biological roles induced by IL22RA1. In conclusion, NR_003923 and IL22RA1 might contribute to glaucoma progression and be a novel and potential biomarkers and therapeutic targets for glaucoma (Homo sapiens) PubMed

 28348.

RPS23RG1 Is Required for Synaptic Integrity and Rescues Alzheimer's Disease-Associated Cognitive Deficits. (Homo sapiens) PubMed

 28349.

Lnc-NA inhibits proliferation and metastasis in endometrioid endometrial carcinoma through regulation of NR4A1. (Homo sapiens) PubMed

 28350.

Predictive value of mesangial C3 and C4d deposition in IgA nephropathy. (Homo sapiens) PubMed

 28351.

Circular RNA hsa_circ_0054537 sponges miR-130a-3p to promote the progression of renal cell carcinoma through regulating cMet pathway. (Homo sapiens) PubMed

 28352.

oncogenic functions of circ_0029426 are partially attributed to its suppression on miR-197[circ_0029426] (Homo sapiens) PubMed

 28353.

Long noncoding RNA TM1P3 is involved in osteoarthritis by mediating chondrocyte extracellular matrix degradation. (Homo sapiens) PubMed

 28354.

Long noncoding RNA RP11-547D24.1 regulates proliferation and migration in papillary thyroid carcinoma: Identification and validation of a novel long noncoding RNA through integrated analysis of TCGA database. (Homo sapiens) PubMed

 28355.

LncRNA AY promotes hepatocellular carcinoma metastasis by stimulating ITGAV transcription. (Homo sapiens) PubMed

 28356.

LncRNA PAPAS promotes hepatocellular carcinoma by interacting with miR-188-5p. (Homo sapiens) PubMed

 28357.

circRNA0047905 directly binds miR4516 and miR1227-5p, relieving suppression for targets SERPINB5 and MMP11. Down-regulated circRNA0047905 expression in gastric cancer cells inhibited Akt/CREB signaling pathway activation. (circRNA0047905) (microRNA1227-5p) (Homo sapiens) PubMed

 28358.

Over-expressed lncRNA5322 was found to promote proliferation, colony formation ability but inhibit apoptosis of hair follicle stem cells, in addition to up-regulation of the expression of CDK1 and CDK2. LncRNA5322 was found to act as a ceRNA of miR-19b-3p which directly targeted MAPK1. (lncRNA5322) (Homo sapiens) PubMed

 28359.

LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1alpha. (Homo sapiens) PubMed

 28360.

lncRNA DILC is downregulated in osteoarthritis and regulates IL-6 expression in chondrocytes. (Homo sapiens) PubMed

 28361.

Effects of LncRNA Lnc-LIF-AS on cell proliferation, migration and invasion in a human cervical cancer cell line. (Homo sapiens) PubMed

 28362.

[Relationship of Expression of Circ_cgga162 with the Prognosis of Patients with Mantle Cell Lymphoma]. (Homo sapiens) PubMed

 28363.

LncRNA PAPAS promotes oral squamous cell carcinoma by upregulating transforming growth factor-beta1. (Homo sapiens) PubMed

 28364.

Plasma hsa_circ_0027089 is a diagnostic biomarker for hepatitis B virus-related hepatocellular carcinoma. (Homo sapiens) PubMed

 28365.

CircERCC2 ameliorated intervertebral disc degeneration by regulating mitophagy and apoptosis through miR-182-5p/SIRT1 axis. (Homo sapiens) PubMed

 28366.

CircCDR1as upregulates autophagy under hypoxia to promote tumor cell survival via AKT/ERK(1/2)/mTOR signaling pathways in oral squamous cell carcinomas. (Homo sapiens) PubMed

 28367.

Over-expressed LOC101927196 suppressed oxidative stress levels and neuron cell proliferation in a rat model of autism through disrupting the Wnt signaling pathway by targeting FZD3. (Homo sapiens) PubMed

 28368.

Mechanisms underlying the promotion of osteosarcoma cell proliferation and invasion by lncRNA PBB12. (Homo sapiens) PubMed

 28369.

Up-regulation of long intergenic noncoding RNA 01296 in ovarian cancer impacts invasion, apoptosis and cell cycle distribution via regulating EMT. (Homo sapiens) PubMed

 28370.

Long Noncoding RNA Ahit Protects Against Cardiac Hypertrophy Through SUZ12 (Suppressor of Zeste 12 Protein Homolog)-Mediated Downregulation of MEF2A (Myocyte Enhancer Factor 2A). (Homo sapiens) PubMed

 28371.

Hypoxia-induced feedback of HIF-1alpha and lncRNA-CF129 contributes to pancreatic cancer progression through stabilization of p53 protein. (Homo sapiens) PubMed

 28372.

Downregulation of miR-103a-3p Contributes to Endothelial Progenitor Cell Dysfunction in Deep Vein Thrombosis Through PTEN Targeting. (Homo sapiens) PubMed

 28373.

Long non-coding RNA LINC00526 represses glioma progression via forming a double negative feedback loop with AXL. (Homo sapiens) PubMed

 28374.

Long noncoding RNA Unigene56159 promotes glioblastoma multiforme cell proliferation and invasion through negatively regulating microRNA1945p. (Homo sapiens) PubMed

 28375.

A DHX9-lncRNA-MDM2 interaction regulates cell invasion and angiogenesis of cervical cancer. (Homo sapiens) PubMed

 28376.

CircRNA-5692 inhibits the progression of hepatocellular carcinoma by sponging miR-328-5p to enhance DAB2IP expression. (Homo sapiens) PubMed

 28377.

Circular RNA circABCC4 as the ceRNA of miR-1182 facilitates prostate cancer progression by promoting FOXP4 expression. (Homo sapiens) PubMed

 28378.

Long noncoding RNA lncAIS downregulation in mesenchymal stem cells is implicated in the pathogenesis of adolescent idiopathic scoliosis. (Homo sapiens) PubMed

 28379.

The expression of long noncoding RNA CRCAL-3 in colorectal cancer and its impacts on cell proliferation and migration. (Homo sapiens) PubMed

 28380.

Long noncoding RNA EPIC1 interacts with YAP1 to regulate the cell cycle and promote the growth of pancreatic cancer cells. (Homo sapiens) PubMed

 28381.

Circular RNA COL1A2 promotes angiogenesis via regulating miR-29b/VEGF axis in diabetic retinopathy. (Homo sapiens) PubMed

 28382.

Lnc-M2 controls M2 macrophage differentiation via the PKA/CREB pathway. (Homo sapiens) PubMed

 28383.

Overexpression of circ_0005198 sponges miR-1294 to regulate cell proliferation, apoptosis, migration, and invasion in glioma. (Homo sapiens) PubMed

 28384.

Circular RNA circ_0103552 forecasts dismal prognosis and promotes breast cancer cell proliferation and invasion by sponging miR-1236. (Homo sapiens) PubMed

 28385.

Comprehensive circular RNA profiling reveals circ_0002060 as a potential diagnostic biomarkers for osteoporosis. (Homo sapiens) PubMed

 28386.

HOXB13 promotes proliferation, migration, and invasion of glioblastoma through transcriptional upregulation of lncRNA HOXC-AS3. (Homo sapiens) PubMed

 28387.

Dysregulated circRNA_100876 suppresses proliferation of osteosarcoma cancer cells by targeting microRNA-136. (Homo sapiens) PubMed

 28388.

Long non-coding RNA DILC as a potentially useful biomarker for the diagnosis and prognosis of colorectal cancer. (Homo sapiens) PubMed

 28389.

Overexpression of long non-coding RNA LINC00982 suppresses cell proliferation and tumor growth of papillary thyroid carcinoma through PI3K-ATK signaling pathway. (Homo sapiens) PubMed

 28390.

Hsa_circ_0101432 promotes the development of hepatocellular carcinoma (HCC) by adsorbing miR-1258 and miR-622. (Homo sapiens) PubMed

 28391.

LncRNA MALAT1/miR-181a-5p affects the proliferation and adhesion of myeloma cells via regulation of Hippo-YAP signaling pathway. (Homo sapiens) PubMed

 28392.

Downregulation of long noncoding RNA CRNDE suppresses drug resistance of liver cancer cells by increasing microRNA-33a expression and decreasing HMGA2 expression. (Homo sapiens) PubMed

 28393.

The MS-lincRNA landscape reveals a novel lincRNA BCLIN25 that contributes to tumorigenesis by upregulating ERBB2 expression via epigenetic modification and RNA-RNA interactions in breast cancer. (Homo sapiens) PubMed

 28394.

CircRNA hsa_circ_0074834 promotes the osteogenesis-angiogenesis coupling process in bone mesenchymal stem cells (BMSCs) by acting as a ceRNA for miR-942-5p. (Homo sapiens) PubMed

 28395.

Circular RNA TUBD1 Acts as the miR-146a-5p Sponge to Affect the Viability and Pro-Inflammatory Cytokine Production of LX-2 Cells through the TLR4 Pathway. (Homo sapiens) PubMed

 28396.

Inhibition of miR-103a-3p suppresses the proliferation in oral squamous cell carcinoma cells via targeting RCAN1. (Homo sapiens) PubMed

 28397.

LINC01133 inhibits breast cancer invasion and metastasis by negatively regulating SOX4 expression through EZH2. (Homo sapiens) PubMed

 28398.

Circ_0001955 facilitates hepatocellular carcinoma (HCC) tumorigenesis by sponging miR-516a-5p to release TRAF6 and MAPK11. (Homo sapiens) PubMed

 28399.

LncRNA ODIR1 inhibits osteogenic differentiation of hUC-MSCs through the FBXO25/H2BK120ub/H3K4me3/OSX axis. (Homo sapiens) PubMed

 28400.

The novel circCLK3/miR-320a/FoxM1 axis promotes cervical cancer progression. (Homo sapiens) PubMed

 28401.

Hsa_circ_0002483 inhibited the progression and enhanced the Taxol sensitivity of non-small cell lung cancer by targeting miR-182-5p. (Homo sapiens) PubMed

 28402.

Host relieves lnc-IRAK3-3-sequestered miR-891b to attenuate apoptosis in Enterovirus 71 infection. (Homo sapiens) PubMed

 28403.

Long non-coding RNA 00152 promotes cell proliferation in cervical cancer via regulating miR-216b-5p/HOXA1 axis. (Homo sapiens) PubMed

 28404.

Long non-coding RNA DUXAP10 promotes the proliferation, migration, and inhibits apoptosis of prostate cancer cells. (Homo sapiens) PubMed

 28405.

Association of lnc-IL17RA-11 with increased radiation sensitivity and improved prognosis of HPV-positive HNSCC. (Homo sapiens) PubMed

 28406.

Upregulation of long noncoding TNFSF10 contributes to osteoarthritis progression through the miR-376-3p/FGFR1 axis. (Homo sapiens) PubMed

 28407.

LncRNA CADM1-AS1 serves as a new prognostic biomarker for gastric cancer. (Homo sapiens) PubMed

 28408.

Circ_0000003 promotes the proliferation and metastasis of non-small cell lung cancer cells via miR-338-3p/insulin receptor substrate 2. (Homo sapiens) PubMed

 28409.

A novel natural antisense transcript at human SOX9 locus is down-regulated in cancer and stem cells. (Homo sapiens) PubMed

 28410.

Circular RNA circ_0079593 indicates a poor prognosis and facilitates cell growth and invasion by sponging miR-182 and miR-433 in glioma. (Homo sapiens) PubMed

 28411.

Down-regulation of MiR-138-5p Protects Chondrocytes ATDC5 and CHON-001 from IL-1 beta-induced Inflammation Via Up-regulating SOX9. (Homo sapiens) PubMed

 28412.

Mechanism of activation for the sirtuin 6 protein deacylase. (Homo sapiens) PubMed

 28413.

The implication of lncRNA expression pattern and potential function of lncRNA RP4-576H24.2 in acute myeloid leukemia. (Homo sapiens) PubMed

 28414.

HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb. (Homo sapiens) PubMed

 28415.

Decreased H19, GAS5, and linc0597 Expression and Association Analysis of Related Gene Polymorphisms in Rheumatoid Arthritis. (Homo sapiens) PubMed

 28416.

The circular RNA hsa_circ_0007623 acts as a sponge of microRNA-297 and promotes cardiac repair. (Homo sapiens) PubMed

 28417.

Circ_0136474 and MMP-13 suppressed cell proliferation by competitive binding to miR-127-5p in osteoarthritis. (Homo sapiens) PubMed

 28418.

circCPA4 acts as a prognostic factor and regulates the proliferation and metastasis of glioma. (Homo sapiens) PubMed

 28419.

[Value of serum procalcitonin combined with soluble triggering receptor expressed on myeloid cells-1 in the differential diagnosis of bacterial and viral diarrhea in children]. (Homo sapiens) PubMed

 28420.

The IL-22 triggered tripartite-motif protein 30 (TRIM30) association with Sox17, thereby mediating K48-linked polyubiquitination of Sox17.(TRIM30) (Homo sapiens) PubMed

 28421.

PMCA-replicated PrP(D) in urine of vCJD patients maintains infectivity and strain characteristics of brain PrP(D): Transmission study. (Homo sapiens) PubMed

 28422.

The clinical impact of angiotensin-(1-7)/mitochondrial assembly receptor axis in esophageal squamous cell carcinoma patients receiving curative esophagectomy. (Homo sapiens) PubMed

 28423.

Circ_0006332 promotes growth and progression of bladder cancer by modulating MYBL2 expression via miR-143. (Homo sapiens) PubMed

 28424.

Long non-coding RNA ENST00000434223 inhibits the progression of renal cancer through Wnt/hygro-catenin signaling pathway. (Homo sapiens) PubMed

 28425.

Long non-coding RNA GClnc1 promotes progression of colorectal cancer by inhibiting p53 signaling pathway. (Homo sapiens) PubMed

 28426.

Long non-coding RNA AK027294 promotes tumor growth by upregulating PCNA in gastric cancer. (Homo sapiens) PubMed

 28427.

LncRNA AB073614 promotes tumor migration and invasion by repressing CDKN1A in non-small cell lung cancer. (Homo sapiens) PubMed

 28428.

LncRNA TCF7 triggered endoplasmic reticulum stress through a sponge action with miR-200c in patients with diabetic nephropathy. (Homo sapiens) PubMed

 28429.

LncRNA AC093818.1 accelerates gastric cancer metastasis by epigenetically promoting PDK1 expression. (Homo sapiens) PubMed

 28430.

Long noncoding RNA GMAN promotes hepatocellular carcinoma progression by interacting with eIF4B. (Homo sapiens) PubMed

 28431.

Long noncoding RNA profile revealed by microarray indicates that lncCUEDC1 serves a negative regulatory role in breast cancer stem cells. (Homo sapiens) PubMed

 28432.

hsa_circ_0000745 promotes cervical cancer by increasing cell proliferation, migration, and invasion. (Homo sapiens) PubMed

 28433.

Long non-coding RNA TGLC15 advances hepatocellular carcinoma by stabilizing Sox4. (Homo sapiens) PubMed

 28434.

Long non-coding RNA KDM5B anti-sense RNA 1 enhances tumor progression in non-small cell lung cancer. (Homo sapiens) PubMed

 28435.

Circular circ_0000885 promotes hepatocellular carcinoma proliferation by epigenetically upregulating Caprin1. (Homo sapiens) PubMed

 28436.

MiR-199 inhibits EMT and invasion of hepatoma cells through inhibition of Snail expression. (Homo sapiens) PubMed

 28437.

Hsa_circ_0088036 promotes the proliferation and migration of fibroblast-like synoviocytes by sponging miR-140-3p and upregulating SIRT 1 expression in rheumatoid arthritis. (Homo sapiens) PubMed

 28438.

Hsa_circ_0086414 Might Be a Diagnostic Biomarker of Oral Squamous Cell Carcinoma. (Homo sapiens) PubMed

 28439.

Long Non-Coding RNA (lncRNA) BMP/OP-Responsive Gene (BORG) Promotes Development of Chemoresistance of Colorectal Cancer Cells to Carboplatin. (Homo sapiens) PubMed

 28440.

Circular RNA VRK1 correlates with favourable prognosis, inhibits cell proliferation but promotes apoptosis in breast cancer. (Homo sapiens) PubMed

 28441.

Relationship Between Stage-specific Embryonic Antigen-4 and Anti-cancer Effects of Neoadjuvant Hormonal Therapy in Prostate Cancer. (Homo sapiens) PubMed

 28442.

MicroRNA-200c expression is decreased in hepatocellular carcinoma and associated with poor prognosis. (Homo sapiens) PubMed

 28443.

Identification of Renal Long Non-coding RNA RP11-2B6.2 as a Positive Regulator of Type I Interferon Signaling Pathway in Lupus Nephritis. (Homo sapiens) PubMed

 28444.

Circular RNA hsa_circRNA_103809 promoted hepatocellular carcinoma development by regulating miR-377-3p/FGFR1/ERK axis. (Homo sapiens) PubMed

 28445.

A Human Long Non-coding RNA LncATV Promotes Virus Replication Through Restricting RIG-I-Mediated Innate Immunity. (Homo sapiens) PubMed

 28446.

LncRNA E2F-Mediated Cell Proliferation Enhancing lncRNA Regulates Cancer Cell Behaviors and Affects Prognosis of Gastric Cancer. (Homo sapiens) PubMed

 28447.

Long noncoding RNA SNHG12 indicates the prognosis of prostate cancer and accelerates tumorigenesis via sponging miR-133b. (Homo sapiens) PubMed

 28448.

Hsa_circ_0039411 promotes tumorigenesis and progression of papillary thyroid cancer by miR-1179/ABCA9 and miR-1205/MTA1 signaling pathways. (Homo sapiens) PubMed

 28449.

Hsa_circ_0006948 enhances cancer progression and epithelial-mesenchymal transition through the miR-490-3p/HMGA2 axis in esophageal squamous cell carcinoma. (Homo sapiens) PubMed

 28450.

Long noncoding RNA ENST00000413528 sponges microRNA-593-5p to modulate human glioma growth via polo-like kinase 1. (Homo sapiens) PubMed

 28451.

In silico prediction of housekeeping long intergenic non-coding RNAs reveals HKlincR1 as an essential player in lung cancer cell survival. (Homo sapiens) PubMed

 28452.

Regulation of Cholesterol Homeostasis by a Novel Long Non-coding RNA LASER. (Homo sapiens) PubMed

 28453.

Circular RNA hsa_circ_0001588 promotes the malignant progression of lung adenocarcinoma by modulating miR-524-3p/NACC1 signaling. (Homo sapiens) PubMed

 28454.

Circ_0010220-mediated miR-503-5p/CDCA4 axis contributes to osteosarcoma progression tumorigenesis. (Homo sapiens) PubMed

 28455.

Characterization of hsa_circ_0000594 as a new biomarker and therapeutic target for hepatoblastoma. (Homo sapiens) PubMed

 28456.

Comprehensive multi-omics analysis uncovers a group of TGF-beta-regulated genes among lncRNA EPR direct transcriptional targets. (Homo sapiens) PubMed

 28457.

Circular RNA hsa_circ_0084443 Is Upregulated in Diabetic Foot Ulcer and Modulates Keratinocyte Migration and Proliferation. (Homo sapiens) PubMed

 28458.

Aberrant expression of lncRNA MALAT1 modulates radioresistance in colorectal cancer in vitro via miR-101-3p sponging. (Homo sapiens) PubMed

 28459.

hsa_circ_0006459 and hsa_circ_0015962 affect prognosis of Dengue fever. (Homo sapiens) PubMed

 28460.

LINC00459 sponging miR-218 to elevate DKK3 inhibits proliferation and invasion in melanoma. (Homo sapiens) PubMed

 28461.

A novel long noncoding RNA, AC092834.1, regulates the adipogenic differentiation of human adipose-derived mesenchymal stem cells via the DKK1/Wnt/beta-catenin signaling pathway. (Homo sapiens) PubMed

 28462.

[The value of serum abnormal prothrombin in clinical application of hepatocellular carcinoma]. (Homo sapiens) PubMed

 28463.

Upregulated long noncoding RNA ENST00000470447.1 inhibits cell migration and invasion and predicts better disease-free survival of oral cancer. (Homo sapiens) PubMed

 28464.

LncRNA ARFRP1 knockdown inhibits LPS-induced the injury of chondrocytes by regulation of NF-kappaB pathway through modulating miR-15a-5p/TLR4 axis. (Homo sapiens) PubMed

 28465.

LncRNA DILA1 inhibits Cyclin D1 degradation and contributes to tamoxifen resistance in breast cancer. (Homo sapiens) PubMed

 28466.

Upregulation of GPNCA is associated with poor prognosis through enhancement of tumor growth via regulating GSK3B. (Homo sapiens) PubMed

 28467.

Evaluation of serum human epididymis protein 4 in patients with relapsing-remitting multiple sclerosis. (Homo sapiens) PubMed

 28468.

MiR103a-3p and miR107 are related to adaptive coping in a cluster of fibromyalgia patients. (Homo sapiens) PubMed

 28469.

Comprehensive analysis of translation from overexpressed circular RNAs reveals pervasive translation from linear transcripts. (Homo sapiens) PubMed

 28470.

Risk SNP-Mediated Enhancer-Promoter Interaction Drives Colorectal Cancer through Both FADS2 and AP002754.2. (Homo sapiens) PubMed

 28471.

Long Non-coding RNA HIX003209 Promotes Inflammation by Sponging miR-6089 via TLR4/NF-kappaB Signaling Pathway in Rheumatoid Arthritis. (Homo sapiens) PubMed

 28472.

Possible involvement of PS-PLA1 and lysophosphatidylserine receptor (LPS1) in hepatocellular carcinoma. (Homo sapiens) PubMed

 28473.

Long non-coding RNA 91H regulates IGF2 expression by interacting with IGF2BP2 and promotes tumorigenesis in colorectal cancer. (Homo sapiens) PubMed

 28474.

Downregulation of TNFRSF19 and RAB43 by a novel miRNA, miR-HCC3, promotes proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma cells. (Homo sapiens) PubMed

 28475.

Circular RNA circ-RELL1 regulates inflammatory response by miR-6873-3p/MyD88/NF-kappaB axis in endothelial cells. (Homo sapiens) PubMed

 28476.

lncRNACNN3-206 activates intestinal epithelial cell apoptosis and invasion by sponging miR-212, an implication for Crohn's disease. (Homo sapiens) PubMed

 28477.

Circular RNA hsa_circ_0000467 Promotes the Development of Gastric Cancer by Competitively Binding to MicroRNA miR-326-3p. (Homo sapiens) PubMed

 28478.

GOLT1A-KISS1 fusion is associated with metastasis in adenoid cystic carcinomas. (Homo sapiens) PubMed

 28479.

Circ0004390 promotes cell proliferation through sponging miR-198 in ovarian cancer. (Homo sapiens) PubMed

 28480.

Long noncoding RNA CMPK2 promotes colorectal cancer progression by activating the FUBP3-c-Myc axis. (Homo sapiens) PubMed

 28481.

Knockdown of Long Noncoding RNA (lncRNA) AK094457 Relieved Angiotensin II Induced Vascular Endothelial Cell Injury. (Homo sapiens) PubMed

 28482.

Small Nucleolar RNA Host Gene 1 (SNHG1) and Chromosome 2 Open Reading Frame 48 (C2orf48) as Potential Prognostic Signatures for Liver Cancer by Constructing Regulatory Networks. (Homo sapiens) PubMed

 28483.

C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1. (Homo sapiens) PubMed

 28484.

Long noncoding RNA PENG upregulates PDZK1 expression by sponging miR-15b to suppress clear cell renal cell carcinoma cell proliferation. (Homo sapiens) PubMed

 28485.

[Effect of miR-148b-3p on invasion and migration of glioma cells by regulating Wnt signaling pathway]. (Homo sapiens) PubMed

 28486.

Decipher manifestations and Treg /Th17 imbalance in multi-staging rheumatoid arthritis and correlation with TSDR/RORC methylation. (Homo sapiens) PubMed

 28487.

The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition. (Homo sapiens) PubMed

 28488.

LINC00319 promotes migration, invasion and epithelial-mesenchymal transition process in cervical cancer by regulating miR-3127-5p/RPP25 axis. (Homo sapiens) PubMed

 28489.

Wisteria floribunda agglutinin-positive mac-2 binding protein as an age-independent fibrosis marker in nonalcoholic fatty liver disease. (Homo sapiens) PubMed

 28490.

LncRNA RP11-86H7.1 promotes airway inflammation induced by TRAPM2.5 by acting as a ceRNA of miRNA-9-5p to regulate NFKB1 in HBECS. (Homo sapiens) PubMed

 28491.

CircRNA_100876 promote proliferation and metastasis of breast cancer cells through adsorbing microRNA-361-3p in a sponge form. (Homo sapiens) PubMed

 28492.

Circular RNA-0001283 Suppresses Breast Cancer Proliferation and Invasion via MiR-187/HIPK3 Axis. (Homo sapiens) PubMed

 28493.

LOC101060264 Silencing Suppresses Invasion and Metastasis of Human Colon Cancer. (Homo sapiens) PubMed

 28494.

Long non-coding RNA TIRY promotes tumor metastasis by enhancing epithelial-to-mesenchymal transition in oral cancer. (Homo sapiens) PubMed

 28495.

Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI. (Homo sapiens) PubMed

 28496.

A novel circular RNA, circ-ATAD1, contributes to gastric cancer cell progression by targeting miR-140-3p/YY1/PCIF1 signaling axis. (Homo sapiens) PubMed

 28497.

Exosome-mediated transfer of circRNA CircNFIX enhances temozolomide resistance in glioma. (Homo sapiens) PubMed

 28498.

LncRNA-01126 inhibits the migration of human periodontal ligament cells through MEK/ERK signaling pathway. (Homo sapiens) PubMed

 28499.

Circular RNA hsa_circ_0053277 promotes the development of colorectal cancer by upregulating matrix metallopeptidase 14 via miR-2467-3p sequestration. (Homo sapiens) PubMed

 28500.

LncRNA PCGEM1 enhances metastasis and gastric cancer invasion through targeting of miR-129-5p to regulate P4HA2 expression. (Homo sapiens) PubMed

 28501.

DICER-AS1 lncRNA: A putative culprit in the pathogenesis of gastric cancer. (Homo sapiens) PubMed

 28502.

Clinical relevance of the lnc-HNF1B-3:1 genetic polymorphisms in Western Chinese tuberculosis patients. (Homo sapiens) PubMed

 28503.

Circ-MTO1 correlates with favorable prognosis and inhibits cell proliferation, invasion as well as miR-17-5p expression in prostate cancer. (Homo sapiens) PubMed

 28504.

Reduced expression of circRNA hsa_circ_0067582 in human gastric cancer and its potential diagnostic values. (Homo sapiens) PubMed

 28505.

Specific circulating microRNAs during hepatitis E infection can serve as indicator for chronic hepatitis E. (Homo sapiens) PubMed

 28506.

Circular RNA circ_0067934 functions as an oncogene in glioma by targeting CSF1. (Homo sapiens) PubMed

 28507.

The correlation of long non-coding RNA intersectin 1-2 with disease risk, disease severity, inflammation, and prognosis of acute ischemic stroke. (Homo sapiens) PubMed

 28508.

Circular RNA 406961 interacts with ILF2 to regulate PM2.5-induced inflammatory responses in human bronchial epithelial cells via activation of STAT3/JNK pathways. (Homo sapiens) PubMed

 28509.

Exosome-transmitted circular RNA hsa_circ_0051443 suppresses hepatocellular carcinoma progression. (Homo sapiens) PubMed

 28510.

Circular RNA circHIAT1 inhibits proliferation and epithelial-mesenchymal transition of gastric cancer cell lines through downregulation of miR-21. (Homo sapiens) PubMed

 28511.

LncRNA MST1P2/miR-133b axis affects the chemoresistance of bladder cancer to cisplatin-based therapy via Sirt1/p53 signaling. (Homo sapiens) PubMed

 28512.

Plasma miR-125a and miR-125b in sepsis: Correlation with disease risk, inflammation, severity, and prognosis. (Homo sapiens) PubMed

 28513.

Circular RNA hsa_circ_0000285 acts as an oncogene in laryngocarcinoma by inducing Wnt/beta-catenin signaling pathway. (Homo sapiens) PubMed

 28514.

Concomitant overexpression of Activin A and p63 is associated with poor outcome in oral cancer patients. (Homo sapiens) PubMed

 28515.

Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m(6)A modification. (Homo sapiens) PubMed

 28516.

Overexpression of Long Noncoding RNA Uc.187 Induces Preeclampsia-Like Symptoms in Pregnancy Rats. (Homo sapiens) PubMed

 28517.

RP11-81H3.2 Acts as an Oncogene via microRNA-490-3p Inhibition and Consequential Tankyrase 2 Up-Regulation in Hepatocellular Carcinoma. (Homo sapiens) PubMed

 28518.

LncRNA ANCR Promotes Invasion and Migration of Gastric Cancer by Regulating FoxO1 Expression to Inhibit Macrophage M1 Polarization. (Homo sapiens) PubMed

 28519.

Circ_0005075 stimulates the proliferation and metastasis of glioma via downregulating SIRT1. (Homo sapiens) PubMed

 28520.

Involvement of the gamma1 subunit of the large-conductance Ca(2+)-activated K(+) channel in the proliferation of human somatostatinoma cells. (Homo sapiens) PubMed

 28521.

The role of the novel LincRNA uc002jit.1 in NF-kB-mediated DNA damage repair in acute myeloid leukemia cells. (Homo sapiens) PubMed

 28522.

CircRNA BIRC6 promotes non-small cell lung cancer cell progression by sponging microRNA-145. (Homo sapiens) PubMed

 28523.

Hypoxia-induced lncRNA RP11-390F4.3 promotes epithelial-mesenchymal transition (EMT) and metastasis through upregulating EMT regulators. (Homo sapiens) PubMed

 28524.

LncRNA OIP5-AS1 induces epithelial-to-mesenchymal transition and renal fibrosis in diabetic nephropathy via binding to miR-30c-5p. (Homo sapiens) PubMed

 28525.

[Over-expression of circNR4A1/Hsa-circ-0026352 inhibits proliferation and induces apoptosis in MCF-7 cells]. (Homo sapiens) PubMed

 28526.

RACB might be a common signaling element in response to both biotic and abiotic stress [RACB] (Hordeum vulgare) PubMed

 28527.

Gibberellin-dependent induction of isocitrate lyase activity is mediated by SLENDER1 and requires cGMP, but does not involve the transcription factor GAMYB [SLENDER1 & GAMYB] (Hordeum vulgare) PubMed

 28528.

expression of barley sbeIIb was sugar inducible, whereas that of sorghum sbeIIb was not [sbeIIb] (Hordeum vulgare) PubMed

 28529.

MYBS3 is an activator of gene expression both during endosperm development and in aleurone cells upon seed germination. (Hordeum vulgare) PubMed

 28530.

Results describe the gene Jekyll, which encodes a novel protein involved in the sexual reproduction of barley [Jekyll]. (Hordeum vulgare) PubMed

 28531.

The isolation and characterization of beta-D-mannanase (MAN1) from H. vulgare, is reported.[MAN1] (Hordeum vulgare) PubMed

 28532.

Two PAO genes evolve separately after a duplication event to code for two distinct tissue-specific enzymes, which are likely to play different physiological roles. (Pao1 and Pao2 = polyamine oxidase 1 and 2) (Hordeum vulgare) PubMed

 28533.

The genetic mapping, gene structures, and analysis of amino-acid sequences of the Rpg1 gene family members are presented. (Hordeum vulgare) PubMed

 28534.

Novel sequence data from intron III of the Bmy1 gene is discussed. (Hordeum vulgare) PubMed

 28535.

Hvbcat1 is regulated by drought stress and has been mapped to chromosome 4H. [BCAT-1] (Hordeum vulgare) PubMed

 28536.

female-specific marker in the dioecious species Asparagus officinalis L (Hordeum vulgare) PubMed

 28537.

An alternate transcript produced from Hv.AGP.S.1, Hv.1b, encodes a plastidial small subunit of ADP-glucose pyrophosphorylase (AGPase) that is required for >90% of the AGPase activity in the leaves. [Hv.AGP.S.1] (Hordeum vulgare) PubMed

 28538.

HvRBOHA has a role in the cellular accessibility of Barley to Blumeria graminis. [Respiratory burst oxidase homologue A (RBOHA)] (Hordeum vulgare) PubMed

 28539.

The barley enhanced Magnaporthe resistance (emr1) mutant which showed restored resistance against blast in the absence of wild-type MLO is described.[EMR1; MLO] (Hordeum vulgare) PubMed

 28540.

Analysis of the hydrolysis products showed that it is an endo-acting enzyme which has the striking ability to release xylose from both polymeric xylan as well as from small xylo-oligosaccharides.[endo-beta-1,4-xylanase X-I] (Hordeum vulgare) PubMed

 28541.

HvWRKY38 has a role as a converging node of salicylic acid and abscisic acid signal pathways involved in suppressing gibberellin-induced seed germination. (Hordeum vulgare) PubMed

 28542.

Actin-dependent and actin-independent resistance pathways acting at the cell periphery appear to be under negative control by the plasma membrane-resident MLO protein. [MLO] (Hordeum vulgare) PubMed

 28543.

These IDE-like sequences would be the first candidates for the functional iron-deficiency-responsive elements in the IDS3 promoter [IDS3] (Hordeum vulgare) PubMed

 28544.

At mitotic metaphase, CENH3, histone H3, and serine 10 phosphorylated histone H3 predominated within distinct structural subdomains of the centromere (CENH3) (Hordeum vulgare) PubMed

 28545.

HvSR has been cloned and characterized. (Hordeum vulgare) PubMed

 28546.

HvMATE, a gene encoding a multidrug and toxic compound extrusion protein, is identified as having a role in controlling Aluminium tolerance in barley. (Hordeum vulgare) PubMed

 28547.

These results suggest that Frost Resistance Fr-H1 acts in part to repress or attenuate expression of the Cbf at Fr-H2.[Fr-H1; Fr-H2] (Hordeum vulgare) PubMed

 28548.

Results report the crystal structure of the cyanide-bound hexacoordinate hemoglobin from barley [hemoglobin] (Hordeum vulgare) PubMed

 28549.

DOF19 binds in a specific manner to the pyrimidine box within the GARC of a thiol-protease gene (Al21), and mediates the ABA repression of this gene in the barley aleurone [Dof19] (Hordeum vulgare) PubMed

 28550.

P23k is involved in the synthesis of cell wall polysaccharides and contributes to secondary wall formation in barley leaves. (Hordeum vulgare) PubMed

 28551.

expression of HvPIP1;6 was highest in the elongation zone; in elongation zone, faster growing regions showed higher expression than slower growing regions expression was confined to epidermis with some expression in neighboring mesophyll cells [PIP1;6] (Hordeum vulgare) PubMed

 28552.

The effects of expressing the barley proline transporter (HvProT) under the control of either the CaMV35S promoter (35Sp) or a root cap promoter (RCp), on Arabidopsis growth are reported. (Hordeum vulgare) PubMed

 28553.

The identification and molecular characterization of barley FUSCA3, a B3-type transcription factor as yet uncharacterized in monocotyledonous plants; both the barley and Arabidopsis FUS3 genes maintain a conserved functionality.[FUSCA3] (Hordeum vulgare) PubMed

 28554.

The amount of accumulated DHN5 after a certain period of cold acclimation differed according to the growth habits of cultivars and can be used as a marker for determination of frost tolerance in barley.[Dehydrin 5] (Hordeum vulgare) PubMed

 28555.

These findings indicate that PI4 kinase acts as a positive regulator of early gibberellic acid signaling in aleurone.[PI3 kinase, PI4 kinase] (Hordeum vulgare) PubMed

 28556.

A class of Trx targets including TIC55, PTC52 and LLS1 in the inner plastid envelope membrane of chloroplasts that share a CxxC motif approximately 73 aa from their carboxyl-terminal end, were identified.[PTC52, LLS1, TIC55] (Hordeum vulgare) PubMed

 28557.

Lil3 is the pigment-binding complex subunit presnt in pigment-binding protein complexes de novo accumulated in dark-grown barley seedlings upon illumination. (Hordeum vulgare) PubMed

 28558.

RIC171, a CRIB protein, interacts with RACB.(RIC171)(RACB) (Hordeum vulgare) PubMed

 28559.

AMY1 showed the highest activity at 0.1-5 mM calcium concentration, whereas 15-20 mM was optimal for AMY2.[amy2] (Hordeum vulgare) PubMed

 28560.

results provide evidence that there have been only few evolutionary changes in Hv- and TaGAMYB; this confirms the close relationship between these species and also highlights the functional importance of this transcription factor [GAMYB] (Hordeum vulgare) PubMed

 28561.

Data indicate that the inositol monophosphatase-1 (IMP-1) gene is regulated at least in part in response to myo-inositol metabolic needs, and that the enzyme it encodes has catalytic properties well suited for a role in myo-inositol synthesis (IMP-1). (Hordeum vulgare) PubMed

 28562.

Three ATG triplets in the polylinker decreased the synthesis of the HKT1 transporter and that the lower amount of transporter caused the functional change.[HKT1] (Hordeum vulgare) PubMed

 28563.

HVA22 is an ER- and Golgi-localized protein capable of negatively regulating GA-mediated vacuolation/programmed cell death in barley aleurone cells. (Hordeum vulgare) PubMed

 28564.

results highlight the impact of Rom1 in basal defence of barley against different pathogens; a tissue-specific function for Rom1 with contrasting effects on epidermal and mesophyll defence was demonstrated [Rom1] (Hordeum vulgare) PubMed

 28565.

Des5, in addition to Dek1, Cr4, and Sal1, plays role in seed development. [Des5, Cr4, Sal1] (Hordeum vulgare) PubMed

 28566.

The barley stem rust resistance genes Rpg5 and rpg4 by map-based cloning were isolated. (Hordeum vulgare) PubMed

 28567.

The present work focused on changes in PLD and G3PDH activities, hydrogen peroxide production, and on alterations of root lipids in Hordeum vulgare following short periods of K+ starvation.[PLD] (Hordeum vulgare) PubMed

 28568.

[3 genes] Genetic variation at Ppd-H1 is strongly associated with flowering time in Barley. [Ppd-H1] The association between flowering time and variation at HvFT1 and HvCO1 is strongly dependent on the haplotype present at Ppd-H1. [HvFT1, HvCO1] (Hordeum vulgare) PubMed

 28569.

BAX inhibitor-1 (BI-1) is associated with susceptibility to fungal pathogens. (Hordeum vulgare) PubMed

 28570.

The NecS1 gene is predicted to encode a cation/proton exchanging protein envolved in necrosis and disease resistance. (Hordeum vulgare) PubMed

 28571.

HvLsi1 is a silicon influx transporter that is involved in radial transport of Si through the epidermal and cortical layers of the basal roots of barley. [HsLsi1] (Hordeum vulgare) PubMed

 28572.

Tetratricopeptide repeat (TPR) domains 6, 8, and 9 of the SPY gene are neither absolutely essential nor sufficient for SPY activity. (Hordeum vulgare) PubMed

 28573.

PG1 and ECA1 are activated during the switching of microspores to the embryogenic pathway. [ECA1] (Hordeum vulgare) PubMed

 28574.

ABF transcription factors interact with PKABA1 and 14-3-3 proteins, and suppress gibberellic acid signalling. [ABF1; ABF2] (Hordeum vulgare) PubMed

 28575.

The barley (Hordeum vulgare) magnesium chelatase large subunit, XanF, does not function as an abscisic acid receptor. [XanF] (Hordeum vulgare) PubMed

 28576.

Results describe a novel, activation-tagged barley mutant that results from antisense suppression of a uroporphyrinogen III synthase (Uros) gene, the product of which catalyzes the sixth step in the synthesis of chlorophyll and heme. (Hordeum vulgare) PubMed

 28577.

Phosphorylation of CP29 may facilitate disassociation of light-harvesting complex (LHCII) from photosystem II (PSII) complex, disassembly of the LHCII trimer and its subsequent degradation.[CP29] (Hordeum vulgare) PubMed

 28578.

HvHDAC2-1 and HvHDAC2-2 are histone deacetylaces thatrespond to treatments with plant stress-related hormones. [HvHDAC2-1; HvHDAC2-2] (Hordeum vulgare) PubMed

 28579.

The barley AP2-like gene is located on chromosome 5Hch. [AP2-like] (Hordeum vulgare) PubMed

 28580.

The expression of YS1 was induced by Fe deficiency only in barley roots. [Ys1] (Hordeum vulgare) PubMed

 28581.

Expression of both aquaglyceroporin genes, HvPIP1;3 and HvPIP1;4, in yeast resulted in increased B sensitivity. [HvPIP1;3 and HvPIP1;4] (Hordeum vulgare) PubMed

 28582.

The chromosomal region of the bst1 mutation is genetically defined and important defence signalling molecules induced on fungal challenge on bst1, were studied.[bst1] (Hordeum vulgare) PubMed

 28583.

Findings suggest that RRP46 mediates RNA processing and degradation involved in cell death initiation as a result of attempted penetration by Bgh during the barley-powdery mildew interaction but is independent of gene-for-gene resistance. [RRP46] (Hordeum vulgare) PubMed

 28584.

isolation of cleistogamy 1 (Cly1); show it encodes a transcription factor containing 2 AP2 domains & putative miR172 targeting site; conclude miR172-derived downregulation of Cly1 promotes development of the lodicules, ensuring noncleistogamy [Cly1] (Hordeum vulgare) PubMed

 28585.

The Rrs2 gene was fine mapped to an interval of 0.08 cM between markers 693M6_6 and P1D23R on the distal end of barley chromosome 7HS using an Atlas (resistant) x Steffi (susceptible) mapping population of 9,179 F(2)-plants. (Hordeum vulgare) PubMed

 28586.

HvPHT1;6 is most likely to be a proton-coupled Pi transporter. [PHT1;6] (Hordeum vulgare) PubMed

 28587.

In the present work three full-length sequences encoding members of the GNAT/MYST family, namely HvMYST, HvELP3 and HvGCN5, respectively, were isolated and characterized from barley (Hordeum vulgare L.).. (Hordeum vulgare) PubMed

 28588.

The results suggest that plastid-located Whirly1 functions primarily in RNA metabolism rather than as a DNA binding protein. (Hordeum vulgare) PubMed

 28589.

Reaction kinetics and thermodynamic properties were readily determined for HvTrxh1 than HvTrxh2.[hvTrxh1, HvTrxh2] (Hordeum vulgare) PubMed

 28590.

Misexpression of RBOHF2 caused failure of barley to normally develop penetration resistance to B. graminis f. sp. hordei and to control leaf cell death.[RBOHF2] (Hordeum vulgare) PubMed

 28591.

These data support a function of BAX INHIBITOR-1 (BI-1) in modulating cell-wall-associated defense and in establishing full compatibility of B. graminis f. sp. hordei with barley.[BI-1] (Hordeum vulgare) PubMed

 28592.

Double mutant analysis determined that the lnt1 mutant was epistatic to five of the six low and high tillering mutants tested.[lnt-1] (Hordeum vulgare) PubMed

 28593.

Substrate specificity of Os3BGlu7 and HvBII depends on the inherent conformational and spatial flexibilities of gluco- and manno-configured substrates in the enzymes' active sites [HvBII] (Hordeum vulgare) PubMed

 28594.

Rdg2a mediates resistance to leaf stripe in the absence of hypersensitive cell death.[Rdg2a] (Hordeum vulgare) PubMed

 28595.

Data provide convergent evidence for a role of the HvWIR1a gene and possibly other family members, during the interaction of barley with B. graminis. [WIR1] (Hordeum vulgare) PubMed

 28596.

[lunasin]identification and quantification of lunasin in seeds of all 9 cultivars investigated; cv. Salrok has highest lunasin content, cv. Nonghwa has lowest (Hordeum vulgare) PubMed

 28597.

Results suggest that HvCEBiP is involved in basal resistance against appressorium-mediated infection: [HvCEBiP] (Hordeum vulgare) PubMed

 28598.

INTERMEDIUM-C, a modifier of lateral spikelet fertility in barley, is an ortholog of the maize domestication gene TEOSINTE BRANCHED 1 [INT-C] (Hordeum vulgare) PubMed

 28599.

Data show that ARFA1b/1c is localized to multivesicular bodies, providing a functional link between ROR2 and these organelles in penetration resistance to mildew infection [ARFA1b/1c, ROR2]. (Hordeum vulgare) PubMed

 28600.

The primary role of ALPHA-GLUCOSIDASE97 is in the conversion of maltose to glucose in the endosperm. [HvAGL97] (Hordeum vulgare) PubMed

 28601.

the accumulation of Dhn6 gene could be critical for resistant dehydration in plants [Dhn6] (Hordeum vulgare) PubMed

 28602.

The present results indicated that Tibetan wild barley offers elite alleles of HvHKT1 and HvHKT2 conferring salinity tolerance.[HvHKT1, HvHKT2] (Hordeum vulgare) PubMed

 28603.

The electrophysiological properties, plasma membrane localization and cell-specific expression pattern of HvPHT1;1 support its role in the uptake of inorganic phosphate under low inorganic phosphate conditions.[PHT1;1] (Hordeum vulgare) PubMed

 28604.

crystal structure of the CC homodimerization domain of the innate immune sensor protein MLA10 (Hordeum vulgare) PubMed

 28605.

low phytic acid 1-1 (lpa1-1) mutant identified; gene ortholog of rice Os-lpa-MH86-1 (designated as HvST) was isolated from barley and mapped to chromosome 2HL [HvST] (Hordeum vulgare) PubMed

 28606.

VRNH2 was repressed under short days, and might be involved in repression of PPDH2 and, indirectly, in the regulation of flowering time. [VRNH2; PPDH2] (Hordeum vulgare) PubMed

 28607.

Fframe-shift mutation of CNGC4 displays a necrotic phenotype and differential disease resistance. [CNGC4] (Hordeum vulgare) PubMed

 28608.

Azospirillum inoculation triggered the transcription of PIP2;1. [PIP2;1] (Hordeum vulgare) PubMed

 28609.

The variety of HvFT1 alleles described constitutes an allelic series that may have been a factor in agro-ecological adaptation of barley. [HvFT1] (Hordeum vulgare) PubMed

 28610.

HvYSL5 is involved in the transient storage of iron or phytosiderophores.[HvYSL5] (Hordeum vulgare) PubMed

 28611.

Rph20 confers resistance to leaf rust in barley. [Rph20] (Hordeum vulgare) PubMed

 28612.

The combination of Ryd2 and Ryd3 leads to quantitative resistance against Barley yellow dwarf virus-PAV instead of tolerance. [Ryd2; Ryd3] (Hordeum vulgare) PubMed

 28613.

Wheat, barley, maize, and rice all possess purple acid phosphatase (PAP) genes that, expressed in Pichia pastoris, give fully functional phytases (PAPhys) with very similar enzyme kinetics.[PAP] (Hordeum vulgare) PubMed

 28614.

Amo1 locus is tightly linked to the SSIIIa gene and negatively regulates expression of GBSSI. [GBSSI, SSIIIa] (Hordeum vulgare) PubMed

 28615.

Barley plants in which HvHKT2;1 was over-expressed showed increased Na+ loading into the xylem, which led to increased Na+ accumulation in shoot tissues. [HKT2;1] (Hordeum vulgare) PubMed

 28616.

HvYSL2 is localized to endodermal cells in roots under Fe-deficient conditions, and can transport a variety of metal-phytosiderophore complexes. [YSL2] (Hordeum vulgare) PubMed

 28617.

PPDH2 expression is mediated by the vernalization pathway in winter cultivars. PPDH2 promotes flowering irrespective of photoperiod under noninductive conditions. [PPDH2] (Hordeum vulgare) PubMed

 28618.

mat-a mutations disturb the flowering pathway, leading to the early phenotype.[Mat-a] (Hordeum vulgare) PubMed

 28619.

The repression of Jekyll impaired pollen maturation, anther dehiscence and induced a significant loss of fertility.[Jekyll] (Hordeum vulgare) PubMed

 28620.

the expression of Prp1 gene may be up-regulated by the increase of pre-mRNAs during seed development and under abiotic stress [Prp1] (Hordeum vulgare) PubMed

 28621.

HvCO1 functions in the control of flowering time in barley. [HvCO1] (Hordeum vulgare) PubMed

 28622.

identified EAM8 as a barley ortholog of the Arabidopsis thaliana circadian clock regulator EARLY FLOWERING3 (ELF3) and demonstrate that eam8 accelerates the transition from vegetative to reproductive growth and inflorescence development[EAM8] (Hordeum vulgare) PubMed

 28623.

HvCRK1 transcripts were observed to accumulate transiently following Bgh inoculation of susceptible barley.[HvCRK1] (Hordeum vulgare) PubMed

 28624.

Trd1 is the GATA transcription factor ortholog of rice Nl1 and maize Tsh1 genes.[Trd1] (Hordeum vulgare) PubMed

 28625.

The barley laccase-like multicopper oxidase (LMCO) gene structure, DNA sequence polymorphism, and putative protein structure are described. (Hordeum vulgare) PubMed

 28626.

MT3 may play a housekeeping role in metal homeostasis, while MT4 may function in Zinc storage in developing and mature grains.[MT3, MT4] (Hordeum vulgare) PubMed

 28627.

The correlation of mutations and phenotypes strongly supports that the barley locus fch2(chlorina-f2 locus) encodes chlorophyllide a oxygenase.[fch2] (Hordeum vulgare) PubMed

 28628.

We report the systematic analyses of MLA10 activity in disease resistance and cell death signaling in barley[MLA10] (Hordeum vulgare) PubMed

 28629.

HvHMA2 functions as a Zn pump in planta and could play a role in root to shoot Zn transport.[HvHMA2] (Hordeum vulgare) PubMed

 28630.

Alanine aminotransferase catalyzes the forward (alanine-forming) reaction with a k(cat) of 25.6 s(-1), the reverse (glutamate-forming) reaction with k(cat) of 12.1 s(-1) and an equilibrium constant of ~0.5. [alanine aminotransferase] (Hordeum vulgare) PubMed

 28631.

Short awn 2 (lks2) encodes a SHI-family transcription factor. Allelism tests showed that lks2 is allelic to unbranched style 4 (ubs4) and breviaristatum-d (ari-d), for which the phenotypes are very short awn and sparse stigma hairs. [lks2] (Hordeum vulgare) PubMed

 28632.

HvSOC1-like1 homologs in Hordeum vulgare are expressed during seed development and in response to vernalization. (Hordeum vulgare) PubMed

 28633.

Two transcription factors, MYBS1 and MYBGA, present in rice (Oryza sativa) and barley (Hordeum vulgare), function to integrate diverse nutrient starvation and gibberellin (GA) signaling pathways during germination of cereal grains. [MYBS1 and MYBGA] (Hordeum vulgare) PubMed

 28634.

The distribution of HvCEN alleles in a large collection of wild and landrace accessions indicates that this involved selection and enrichment of preexisting genetic variants rather than the acquisition of mutations after domestication. [HvCEN] (Hordeum vulgare) PubMed

 28635.

Down-regulation and over-expression of PR17c in epidermal cells of barley confirmed that this protein is important for penetration resistance against the powdery mildew fungus.[PR17c] (Hordeum vulgare) PubMed

 28636.

HvPap-1 is involved in storage protein mobilization during grain germination [Pap-1] (Hordeum vulgare) PubMed

 28637.

Choline oxidation in glycine betaine synthesis is mediated by a peroxisomal NADPH-dependent choline monooxygenase (HvCMO) in barley plants.[HvCMO] (Hordeum vulgare) PubMed

 28638.

Data indicate that HvABCG31/Eibi1 is an ABCG transporter gene, and suggest that drought stress and adaptive natural selection may have been important determinants in the observed sequence variation of HvABCG31 promoter [HvABCG31/Eibi1] (Hordeum vulgare) PubMed

 28639.

HvPRX45 genes have a possible role in root hair-specific production of hydroxyl radicals in barley. (Hordeum vulgare) PubMed

 28640.

The divergence of gene expression pattern contributed to the neofunctionalization of Vrs1. (Hordeum vulgare) PubMed

 28641.

The results revealed stress response and signal transduction pathways that are associated with the uniculm2 (CUL2) gene (CUL2). (Hordeum vulgare) PubMed

 28642.

Data indicate eleven SNPs including 10 from the coding region of small heat shock protein 17.8 (HSP17.8) were detected, which form nine distinguishable haplotypes in the barley collection: [HSP17.8] (Hordeum vulgare) PubMed

 28643.

Increased HvAACT1 expression is associated with increased citrate efflux from root apices and enhanced Al(3+) tolerance. (Hordeum vulgare) PubMed

 28644.

HvMLH3 - quantitative high resolution mapping of foci in pachytene nuclei reveals a strong distal bias and weak interference (Hordeum vulgare) PubMed

 28645.

The study indicates that transcription levels of HVP10 to be a possible basis for variation in shoot Na(+) accumulation and biomass production controlled by the HvNax3 locus under saline conditions (HVP10). (Hordeum vulgare) PubMed

 28646.

Arabidopsis transgenic lines that constitutively expressed the epitope-tagged HvUGT13248 protein exhibited increased resistance to deoxynivalenol (DON) in a seed germination assay and converted DON to DON-3-O-glucoside (D3G). [HvUGT13248] (Hordeum vulgare) PubMed

 28647.

HvCO9 may act as a negative regulator of flowering under non-inductive short-day conditions in barley. [HvCO9] (Hordeum vulgare) PubMed

 28648.

A detailed analysis of the WAK1 gene from barley, is presented.[WAK1] (Hordeum vulgare) PubMed

 28649.

HvNAC6 - affects ABA accumulation and promotes basal resistance against powdery mildew (Hordeum vulgare) PubMed

 28650.

Data suggest that Pho2 is present in cytoplasm and exhibits a molecular weight of 95 kDa; Pho2 is most strongly expressed in germinating grain; studies include partial purification. [Pho2; cytoplasmic starch phosphorylase] (Hordeum vulgare) PubMed

 28651.

The rpg4-mediated resistance against many wheat stem rust pathogen races, including Puccinia graminis f. sp. tritici race TTKSK, rely on the Rpg5 R gene. [Rpg5] (Hordeum vulgare) PubMed

 28652.

The results of phylogenetic and diversity analyses indicate that HvLUX1 was under purifying selection, duplicated at the base of the grass clade, and diverged independently of LUX-like genes in other plant lineages.[HvLUX1] (Hordeum vulgare) PubMed

 28653.

Data suggest a role for HvELMOD_C (HG422171) as a modulator of HvHvMAGAP1 (AK371854)function in fungal entry: [HvELMOD_C] (Hordeum vulgare) PubMed

 28654.

Quantitative trait loci for yield and biomass coincided with the map location of flowering time genes, in particular the vernalisation genes Vrn-H1 and Vrn-H2.[Vrn-H1, vrn-H2] (Hordeum vulgare) PubMed

 28655.

phosphorylation-triggered translocation of HvLhcb1 under Fe deficiency [Lhcb1] (Hordeum vulgare) PubMed

 28656.

A gene encoding a DNA glycosylase closely related to cereal DME glycosylases was characterized in barley.[DME] (Hordeum vulgare) PubMed

 28657.

role of Ycf54 in the MPEC enzyme and the localization of the protein in plastids (Ycf54 protein and MPEC enzyme) (Hordeum vulgare) PubMed

 28658.

The widespread use of mlo resistance to control mildew may have inadvertently stimulated the emergence of Ramularia leaf spot (RLS) as a major disease of barley. [mlo] (Hordeum vulgare) PubMed

 28659.

Disruption of BRI1 has pleiotropic effects on disease resistance in addition to affecting plant development. (Hordeum vulgare) PubMed

 28660.

Data show a reduction in chlorophyll content by 14-18% in magnesium chelatase XanH subunit heterozygous mutants, suggesting semi-dominant mutations: [magnesium chelatase XanH] (Hordeum vulgare) PubMed

 28661.

Results suggest that the natural microclimatic selection appears to adaptively diversify the duplicated copies of hsp17 of wild barley between the opposite warmer and cooler slopes. [Hsp17] (Hordeum vulgare) PubMed

 28662.

HvHsfB2c is co-expressed in the central hub of small heat shock proteins.[HvHsfB2c] (Hordeum vulgare) PubMed

 28663.

These results confirm the conservation of MS1 function in higher plants and in particular in temperate cereals.[MS1] (Hordeum vulgare) PubMed

 28664.

Suppression of both HvABCD1 and HvABCD2 in barley RNA interference lines indicated roles in metabolism of 2,4-dichlorophenoxybutyrate and indole butyric acid, jasmonate biosynthesis, and determination of grain size.[ABCD1,ABCD2] (Hordeum vulgare) PubMed

 28665.

Identified is a thionin proprotein-processing enzyme (TPPE) from barley. [TPPE] (Hordeum vulgare) PubMed

 28666.

KCS6 is providing wax signals for germination of powdery mildew fungi on barley.[KCS6] (Hordeum vulgare) PubMed

 28667.

barley SEX4, was isolated, characterized its gene and protein structure, predicted the cis-elements of its promoter, and analysed its expression.[SEX4] (Hordeum vulgare) PubMed

 28668.

Dark-induced senescence of leaves is mediated by plastid transglutaminase. [transglutaminase] (Hordeum vulgare) PubMed

 28669.

Abscisic acid inhibition of protein storage vacuoles coalescence is mediated by upregulation of HvTIP3;1 expression in aleurone cells. [HvTIP3;1] (Hordeum vulgare) PubMed

 28670.

S40 - senescence-specific mechanism that alters histone modification marks at distinct sequences (Hordeum vulgare) PubMed

 28671.

The study validated the function of the HvPARP3 gene in DSB repair in barley (PARP3). (Hordeum vulgare) PubMed

 28672.

a barley mutant with defect in the 3-KETOACYL-CoA-SYNTHASE (HvKCS6) gene, resulting in reduced coverage of the cuticle with epicuticular waxes.[HvKCS6] (Hordeum vulgare) PubMed

 28673.

AP and G6PDH mutually regulate and maintain photosynthesis and stomata movement in the cross adaptation of highland barley.[AP, G6PDH] (Hordeum vulgare) PubMed

 28674.

The significant reduction in R. collo-cygni symptoms caused by nec1 was completely abolished in the presence of the mlo-5 allele and both symptoms and fungal biomass were greater than in the wild- (Hordeum vulgare) PubMed

 28675.

Dynamic transcriptional changes in uncharacterized HvCslF genes, possibly involved in (1,3;1,4)-beta-glucan synthesis, suggest a role for these genes in the cereal cyst nematode infection process.[HvCslF] (Hordeum vulgare) PubMed

 28676.

WHIRLY1 has a role in communication between plastid and nuclear genes encoding photosynthetic proteins during abiotic stress.[WHIRLY1] (Hordeum vulgare) PubMed

 28677.

These data suggest that CSEP0105 promotes virulence by interfering with the chaperone activity of a barley small heat shock protein essential for defense and stress responses.[Hsp16.9, Hsp17.5] (Hordeum vulgare) PubMed

 28678.

Cul4 acts at axil and leaf boundary regions to control axillary bud differentiation as well as the development of the ligule, which separates the distal blade and proximal sheath of the leaf.[Cul4] (Hordeum vulgare) PubMed

 28679.

Data show that transgenic wheat carrying barley UDP-glucosyltransferase (HvUGT13248) exhibited significantly higher resistance to disease spread in the spike: [HvUGT13248] (Hordeum vulgare) PubMed

 28680.

Nitrate reductase-mediated nitric oxide production is involved in copper tolerance in shoots of hulless barley.[nitrate reductase] (Hordeum vulgare) PubMed

 28681.

Rphq2 does not belong to the NB-LRR gene family and does not resemble any of the partial resistance genes cloned previously. [Rphq2] (Hordeum vulgare) PubMed

 28682.

HvTIP3;1 functions as an active water channel to regulate water movement through tissues during the periods of seed development and desiccation.[HvTIP3;1] (Hordeum vulgare) PubMed

 28683.

The levels of a SLAH3-like slow anion channel transcript, involved in stomatal closure, decreased sharply in G132 mutants. [SLAH3] (Hordeum vulgare) PubMed

 28684.

mapping of barley locus Rps6 conferring resistance to wheat stripe rust (Hordeum vulgare) PubMed

 28685.

Rps6, an intermediate host resistance gene to wheat stripe rust, was mapped in barley (Hordeum vulgare) PubMed

 28686.

CO1 and CO2 proteins control floral repression by up-regulating VRN-H2. [co1] [co2][vrn-h2] (Hordeum vulgare) PubMed

 28687.

The involvement of HvVPS60a in different cell layer-specific trafficking pathways, reflected by localization of HvVPS60a at the plasma membrane in aleurone and at the protein storage vacuole membrane in subaleurone, is discussed.[VPS60] (Hordeum vulgare) PubMed

 28688.

HvSKP1-like, together with HvRBK1, controls the abundance of HvRACB and, at the same time, modulates the outcome of the barley-Blumeria graminis f.sp. hordei interaction.[RACb. (Hordeum vulgare) PubMed

 28689.

the barley genotype CXHKSL possesses a novel allele for the major Al tolerance gene HvAACT1 but the mechanism of tolerance is similar to other tolerant barley lines [AACT1] (Hordeum vulgare) PubMed

 28690.

Transgenic RNA interference barley plants, with reduced expression of the N-end rule pathway N-recognin E3 ligase PROTEOLYSIS6 (HvPRT6), showed increased expression of hypoxia-associated genes and altered seed germination phenotypes.[HvPRT6] (Hordeum vulgare) PubMed

 28691.

a low red to far-red ratio in white light enhances CBF14 expression and increases frost tolerance at 15 degrees C in winter Triticum aesitivum and Hordeum vulgare genotypes, but not in T. monococcum (einkorn), which has a relatively low freezing tolerance. [CBF14] (Hordeum vulgare) PubMed

 28692.

HvSec14p plays essential roles in the biogenesis of membranes in expanding cells and in their preservation under osmotic stress conditions. [HvSec14p] (Hordeum vulgare) PubMed

 28693.

MKK3 regulates seed dormancy.N260T substitution in the dormant allele decreases MKK3 kinase activity.The dormant allele is prevalent in barley cultivars grown in East Asia.[MKK3] (Hordeum vulgare) PubMed

 28694.

BLF1 gene regulates barley leaf size by restricting cell proliferation in the leaf-width direction. [BLF1] (Hordeum vulgare) PubMed

 28695.

rpr2 is required for Rpg1-mediated resistance against stem rust; mapping study of rpr2 [rpr2] (Hordeum vulgare) PubMed

 28696.

Two distinct patterns of sequence diversity for the recessive alleles of two host factors HvPDIL5-1 and HvEIF4E indicated the adaptive selection for bymovirus resistance in cultivated barley from East Asia. [PDIL5-1] (Hordeum vulgare) PubMed

 28697.

HvCERK1 was identified as a candidate gene for Fusarium head blight resistance.[HvCERK1] (Hordeum vulgare) PubMed

 28698.

These results illustrate a diverse expression of genes SnRK2, PYR/PYL/RCAR, and ABF, and suggest a relationship among the six species studied.[SnRK2, PYR, PYL, RCAR, ABF] (Hordeum vulgare) PubMed

 28699.

an alpha/beta hydrolase involved in strigolactone signaling (Hordeum vulgare) PubMed

 28700.

EAM8 is a circadian clock protein. Alternative splicing contributes to early flowering and short-season adaptation [EAM8] (Hordeum vulgare) PubMed

 28701.

The natural variation in (1-->3,1-->4)-beta-glucan endohydrolase leads an increase in thermal stability. [(1-->3,1-->4)-beta-Glucan Endohydrolase ] (Hordeum vulgare) PubMed

 28702.

HvVP1 controls the activation of Hor2 and Amy6.4 promoters exerted by HvGAMYB.[HvVP1, HvGAMYB] (Hordeum vulgare) PubMed

 28703.

The helical propensity of the extracellular loop is responsible for the substrate specificity of Fe(III)-phytosiderophore transporter, yellow stripe 1 protein. [ys1] (Hordeum vulgare) PubMed

 28704.

Results identified Ant2 with regulatory function in anthocyanin biosynthesis in barley grain pericarp. [Ant2] (Hordeum vulgare) PubMed

 28705.

HvCSD1 could be important in the maintenance of the cytosolic redox status and in the differential regulation of responses to pathogens with different lifestyles.[HvCSD1] (Hordeum vulgare) PubMed

 28706.

These results suggest that reactive oxygen species produced by NADPH oxidase are involved in gibberellin biosynthesis.[NADPH oxidase] (Hordeum vulgare) PubMed

 28707.

Genetic interactions of vernalization genes Vrn-H3 with Vrn-H2 and Vrn-H1 also suggested the major role of Vrn-H3 alleles in determining root and shoot trait variations in barley.[Vrn-H3] (Hordeum vulgare) PubMed

 28708.

Map-based cloning enforced by mapping-by-sequencing of the mutant lax-a locus enabled the identification of a homolog of BLADE-ON-PETIOLE1 (BOP1) and BOP2 as the causal gene.[lax-a] (Hordeum vulgare) PubMed

 28709.

The genome-wide association scan identified PHOTOPERIOD-H1 (Ppd-H1) as a candidate gene underlying the major quantitative trait loci for flowering time and leaf size: [Ppd-H1] (Hordeum vulgare) PubMed

 28710.

Major factors contributing to poor K(+) retention ability are (1) an intrinsically lower H(+)-ATPase activity in the root apex, (2) greater salt-induced membrane depolarization, and (3) a higher reactive oxygen species production under sodium chloride.[H ATPase] (Hordeum vulgare) PubMed

 28711.

HvNramp5 is a transporter required for uptake of Manganese and Cadmium, but not for iron, and that barley has a distinct uptake system from rice.[HvNramp5] (Hordeum vulgare) PubMed

 28712.

overexpression of MIR1 specifically compromised MLA-mediated disease resistance in barley.[MIR1] (Hordeum vulgare) PubMed

 28713.

regulates free fatty acid biosynthetic genes to reinforce cuticle to resist Fusarium head blight - [WIN1] (Hordeum vulgare) PubMed

 28714.

actively participates in proteolysis mediated by abiotic treatments of darkness and nitrogen starvation - [HvPap-1] (Hordeum vulgare) PubMed

 28715.

overexpression results in stunting and delay in development combined with early senescence - [NAC005] (Hordeum vulgare) PubMed

 28716.

WHIRLY1 plays a role in light sensing and/or stress communication between chloroplasts and the nucleus.[WHIRLY1] (Hordeum vulgare) PubMed

 28717.

the barley PAPhy_a enzyme is the main contributor to the mature grain phytase activity (MGPA) as grains of knock-out lines show very low MGPA.[HvPAPhy_a] (Hordeum vulgare) PubMed

 28718.

RACB does not interfere with early microbe-associated molecular pattern-triggered immune responses; it also supports rather than restricts expression of defence-related genes. Instead, silencing of RACB expression by RNAi leads to defects in cell polarity.[RACB] (Hordeum vulgare) PubMed

 28719.

Global transcriptional profiling in developing shoot apical meristems of vrs3 suggested that VRS3 acts as a transcriptional activator of the row-type genes.[VRS3] (Hordeum vulgare) PubMed

 28720.

normal synapsis progression was also disrupted in des10, a phenotype that was not evident with standard confocal microscopy and that has not been reported with Mlh3 knockout mutants in Arabidopsis.[HvMLH3, des10] (Hordeum vulgare) PubMed

 28721.

SUT1 and SUT2 sucrose transporters role in the sucrose homeostasis and their expression in developing grains [SUT1] [SUT2] (Hordeum vulgare) PubMed

 28722.

These data suggest the role of TaHDZipI-2 in controlling several key processes underlying frost tolerance, transition to flowering and spike development.[TaHDZipl-2] (Hordeum vulgare) PubMed

 28723.

the effect caused by the 7-bp deletion in exon 1 of HvGA20ox2 gene (the sdw1/denso allele) on the variation of economically important traits in the segregating population of the double haploid lines (DHLs) derived from the cross of the tall barley Morex and the semi-dwarf sdw1.d mutant cv. Barke (HvGA20ox2) (Hordeum vulgare) PubMed

 28724.

Metabolic pathways and genes presumably associated with black lemma and pericarp colour as well as Blp-associated resistance to oxidative stress and pathogens, were revealed. (Black lemma and pericarp (Blp)) (Hordeum vulgare) PubMed

 28725.

encodes a putative Jumonji C-type histone demethylase that regulates expression of other VRS genes and genes involved in stress, hormone and sugar metabolism [VRS3] (Hordeum vulgare) PubMed

 28726.

Mutants in the Brh1 locus are deficient in the Galpha subunit of a heterotrimeric G protein, which shows that heterotrimeric G proteins are important regulators of culm length in barley. Mutant alleles do not have any major negative effects on malting quality. [Brh1] (Hordeum vulgare) PubMed

 28727.

the fra mutation is caused by the introduction of a stop codon in the barley homologue of the rice FLOURY ENDOSPERM 6 (FLO6) gene, and esults in fractured starch granules in barley [fra] (Hordeum vulgare) PubMed

 28728.

The F-group barley bZIPs, HvbZIP56 and HvbZIP62, partially rescue the Zn-dependent growth phenotype and ZIP-transporter gene regulation of an Arabidopsis bzip19-4 bzip23-2 mutant.[HcbZIP56, HvbZIP62] (Hordeum vulgare) PubMed

 28729.

arley RBOHF2 contributes to basal resistance to powdery mildew infection in young leaf tissue but is required to control leaf cell death, salicylic acid accumulation, and defense gene expression in older leaves.[RBOHF2] (Hordeum vulgare) PubMed

 28730.

overexpression of the serine protease inhibitor CI2c in barley has no measurable effect on the performance of the specialist bird cherry-oat aphid, but prevents escape of the generalist green peach aphid from the plants. The higher levels of CI2c in the transgenic plants modify aphid-induced responses, generally to be suppressed, but for a beta-1,3-glucanase to be increased. [CI2] (Hordeum vulgare) PubMed

 28731.

'HOSUT', a winter wheat line expressing a grain-targeted sucrose transporter of barley, had a superior performance for grain yield, aboveground biomass, and ears per plant, obviously due to transgene activity in developing grains and young vegetative sinks.[SUT1] (Hordeum vulgare) PubMed

 28732.

a single dominant gene, Scs6, conferred spot blotch susceptibility in the barley cultivar Bowman [Scs6] (Hordeum vulgare) PubMed

 28733.

encodes an alanine aminotransferase important in the release of dormancy in barley grain [qsd1] (Hordeum vulgare) PubMed

 28734.

24 barley genotypes were examined using specific primers for detecting Vrn-h1and Vrn-h2 loci.[Vrn-h1, Vrn-h2] (Hordeum vulgare) PubMed

 28735.

The contribution of CER-ZH to water barrier properties of the cuticle and its influence on the germination of barley powdery mildew fungus were assessed. [Cer-ZH] (Hordeum vulgare) PubMed

 28736.

HvSERK2 gene plays a positive role in the improvement of barley resistance to powdery mildew.[HvSERK2] (Hordeum vulgare) PubMed

 28737.

mapping of QTLs containing the plant stem rust resistance genes Rpg2 and Rpg3 [Rpg2; Rpg3] (Hordeum vulgare) PubMed

 28738.

The results support a central role of WHIRLY1 in retrograde signaling and also underpin a so far underestimated role of microRNAs in this process. [WHIRLY1] (Hordeum vulgare) PubMed

 28739.

alleles contribute to root phenotypes and can also influence plant responses to root-zone O2-deficiency stress [Sln1] (Hordeum vulgare) PubMed

 28740.

contributes to genome stabilization - [MORC1] (Hordeum vulgare) PubMed

 28741.

Rbs7 is a dominant gene conferring resistance to spot blotch caused by Bipolaris sorokiniana [Rbs7] (Hordeum vulgare) PubMed

 28742.

OS2 expression and role in the vernalization response and flowering.VRN2 expression and role in flowering.[VRN2] [OS2] (Hordeum vulgare) PubMed

 28743.

NLR protein clustered separately from all previously cloned NLRs from the Triticeae; confers leaf rust resistance [Rph1] (Hordeum vulgare) PubMed

 28744.

high affinity hexose transporter [STP13] (Hordeum vulgare) PubMed

 28745.

silencing specifically modifies leaf responses to drought stress - [CPI-2 and CPI-4] (Hordeum vulgare) PubMed

 28746.

allelic variation in the targeted region of HvXYN1 in 210 cultivated barley micro-nucleus germplasms collected from diverse geographical areas (XYN1) (Hordeum vulgare) PubMed

 28747.

study identified a previously unknown miRNA temporally designated as hvu-miRX in barley; in transgenic barley that overexpressed the wheat DREB3 transcription factor (TaDREB3), hvu-miRX was highly expressed compared with the same miRNA in non-transgenic barley [hvu-miRX] (Hordeum vulgare) PubMed

 28748.

HvWRKY23 has a role in barley disease resistance; it regulates flavonoid glycoside and hydroxycinnamic acid amide biosynthetic genes in barley to combat Fusarium head blight [HvWRKY23] (Hordeum vulgare) PubMed

 28749.

barley IRT1 orthologue has a novel function with respect to ensuring sufficient shoot Manganese concentrations.[IRT1] (Hordeum vulgare) PubMed

 28750.

VPE4 expression executes programmed cell death in the pericarp.[VPE4] (Hordeum vulgare) PubMed

 28751.

multiple roles in regulation of seedling growth, stomatal density, and drought stress tolerance - [mir393] (Hordeum vulgare) PubMed

 28752.

positive regulator of drought tolerance - [MYB1] (Hordeum vulgare) PubMed

 28753.

The HORVU4Hr1G074840 gene that encodes a putative cytochrome P450 protein (CYP704B) was identified as the most plausible candidate for MSG26.[CYP704B] (Hordeum vulgare) PubMed

 28754.

results might suggest that early expression of PR genes upon infection in barley cells play a pivotal role in the Agrobacterium-resistance of this plant. (Hordeum vulgare) PubMed

 28755.

essential for development of starchy endosperm and viable grains [PTST1] (Hordeum vulgare) PubMed

 28756.

allele specific increased expression determines shoot sodium exclusion in salt stress = [HKT1;5] (Hordeum vulgare) PubMed

 28757.

Overexpression of FT2 in Brachypodium distachyon and barley results in precocious flowering and reduced spikelet number, while down-regulation by RNA interference results in delayed flowering and a reduced percentage of filled florets. Similarly, truncation mutations of FT2 homeologs in tetraploid wheat delayed flowering (2-4 d) and reduced fertility. [FT2] (Hordeum vulgare) PubMed

 28758.

identification of the ALBOSTRIANS gene HvAST, is reported.[HvAST] (Hordeum vulgare) PubMed

 28759.

Knock-down lines for the protease-encoding genes HvPap-1 and HvPap-19 showed unexpected changes in leaf cuticle thickness and stomatal pore area. The efficiency of photosystem II and the total amount of proteins were almost unaltered in stressed transgenic plants while both parameters decreased in stressed wild-type plants.[Pap-1,Pap-19] (Hordeum vulgare) PubMed

 28760.

The identified mat-c mutant alleles have a negative effect on kernel number and length of spike, which suggest that Mat-c/CEN/TFL1 is less suitable for barley breeding. (HvCEN) (Hordeum vulgare) PubMed

 28761.

des5 exhibits a severe meiotic phenotype with disturbed synapsis, reduced crossovers, and chromosome mis-segregation. The meiotic phenotype and reduced fertility of des5 is similarly observed in Hvdmc1RNAi transgenic plants and HvDMC1p:GusPlus reporter lines show DMC1 expression specifically in the developing inflorescence. [des5,DMC1] (Hordeum vulgare) PubMed

 28762.

After 80 d of NO fumigation, dry matter weight, spikes number, kernel number, and plant kernel weight were significantly increased in HvPgb1.1+ plants with increasing NO concentration. In contrast, yield decreased in WT and HvPgb1.1- plants the higher the NO level. [Pgb1.1] (Hordeum vulgare) PubMed

 28763.

Barley cysteine protease PAP14 plays a role in degradation of chloroplast proteins. (Hordeum vulgare) PubMed

 28764.

CENTRORADIALIS Interacts with FLOWERING LOCUS T-Like Genes to Control Floret Development and Grain Number. (Hordeum vulgare) PubMed

 28765.

A Trypsin Family Protein Gene Controls Tillering and Leaf Shape in Barley. (Hordeum vulgare) PubMed

 28766.

Alternative splicing of a barley gene results in an excess-tillering and semi-dwarf mutant. (Hordeum vulgare) PubMed

 28767.

COMPOSITUM 1 contributes to the architectural simplification of barley inflorescence via meristem identity signals. (Hordeum vulgare) PubMed

 28768.

Barley ROP-Interactive Partner-a organizes into RAC1- and MICROTUBULE-ASSOCIATED ROP-GTPASE ACTIVATING PROTEIN 1-dependent membrane domains. (Hordeum vulgare) PubMed

 28769.

Aquaporin activity of barley tonoplast intrinsic proteins is involved in the delay of the coalescence of protein storage vacuoles in aleurone cells. (Hordeum vulgare) PubMed

 28770.

Identification of dRFX2, a DNA-binding protein, that may have a role in cell cycle progression in the eye imaginal disc [RFX2] (Fly (Drosophila melanogaster dm6)) PubMed

 28771.

Kurzkern mutant embryos fail to form the cephalic furrow and do not accomplsh germband extension and nuclear elongation is significantly reduced. (Fly (Drosophila melanogaster dm6)) PubMed

 28772.

Results suggest an evolutionary conserved role for Sea/SLC25A1 in the regulation of chromosome integrity: [Sea (scheggia)] (Fly (Drosophila melanogaster dm6)) PubMed

 28773.

The Drosophila homologues of membrane-bound O-acyltransferase, Oysgedart (Oys), Nessy (Nes), and Farjavit (Frj), are lysophospholipid acyltransferases.[Oys, Frj] (Fly (Drosophila melanogaster dm6)) PubMed

 28774.

Results describe the novel Ema gene family, identify a new component of the endosomal pathway and provide insights into class C Vps16A-HOPS complex function. (Fly (Drosophila melanogaster dm6)) PubMed

 28775.

[importin-beta 11] importin-beta11 function interacts with the bone morphogenic protein pathway to regulate a pool of phosphorylated mothers against decapentaplegic that must be present at the presynapse for its proper development and function (Fly (Drosophila melanogaster dm6)) PubMed

 28776.

Data report the cloning, characterization, and functional analysis of Dacer, a Drosophila alkaline ceramidase, and suggest that Dacer plays an important role in the Drosophila development and longevity by controlling the metabolism of ceramides. (Fly (Drosophila melanogaster dm6)) PubMed

 28777.

Data help to establish the orientation of each SNAPc subunit on DNA and reveal cases in which different domains of the subunits SNAP43, 50, and 190 differentially contact the U1 versus U6 proximal sequence elements A [SNAP190]. (Fly (Drosophila melanogaster dm6)) PubMed

 28778.

Wingless negatively regulates the function of Ssp by changing its subcellular localization in the salivary gland.[Ssp protein (Sunspot), Drosophila] (Fly (Drosophila melanogaster dm6)) PubMed

 28779.

These results demonstrate that visual behaviors are segregated by the level of GABA signaling in flies, and more generally establish dVGAT as a model to study the contribution of GABA release to other complex behaviors.[dVGAT] (Fly (Drosophila melanogaster dm6)) PubMed

 28780.

Gemin2, Gemin3 and Gemin5 colocalise with SMN in U bodies [gemin3, gemin50 (Fly (Drosophila melanogaster dm6)) PubMed

 28781.

The Drosophila SH2B regulation of insulin-like signaling, growth, and metabolism is conserved in SH2B1, whereas Drosophila SH2B regulation of oxidative stress and longevity may be conserved in other SH2B family members. (Fly (Drosophila melanogaster dm6)) PubMed

 28782.

Verrocchio (Ver), an oligonucleotide/oligosaccharide-binding (OB) fold-containing protein related to Rpa2/Stn1, interacts physically with HOAP and Moi, is enriched only at telomeres, and prevents telomere fusion [Verrocchio (Ver) protein] (Fly (Drosophila melanogaster dm6)) PubMed

 28783.

The beta-carbonic anhydrase showed high CO2 hydratase activity and inhibited by sulfonamide acetazolamide. (Fly (Drosophila melanogaster dm6)) PubMed

 28784.

alpha-synuclein overexpression impairs macroautophagy in mammalian cells and in transgenic mice.[alpha synuclein] (Fly (Drosophila melanogaster dm6)) PubMed

 28785.

Rich controls postsynaptic SSR structure, GluR subunit composition, and muscular growth through a Cdc42-independent pathway.[Rich] (Fly (Drosophila melanogaster dm6)) PubMed

 28786.

Grg expression in the endoderm helps suppress the liver program and find that endodermal competence involves a balance between activators and corepressors [Grg1, Grg3] (Fly (Drosophila melanogaster dm6)) PubMed

 28787.

Instability of the GAL4 transgene can be "cured" by treatment of the line with tetracycline, suggesting that the causative agent is of bacterial origin.[Gal4] (Fly (Drosophila melanogaster dm6)) PubMed

 28788.

Study shows that many invertebrate species contain Sororin-related proteins, and that one of these, Dalmatian, is essential for cohesion in Drosophila.[Dalmation] (Fly (Drosophila melanogaster dm6)) PubMed

 28789.

FoxO targets hid and bim in Drosophila and human, respectively, are responsible for the LRRK2/dLRRK-mediated cell death.[Bim] (Fly (Drosophila melanogaster dm6)) PubMed

 28790.

data indicate that TYF potently activates PER translation in pacemaker neurons to sustain robust rhythms, revealing a new and important role for translational control in the Drosophila circadian clock [TYF=twenty four] (Fly (Drosophila melanogaster dm6)) PubMed

 28791.

Skywalker (Sky) facilitates endosomal trafficking of synaptic vesicles at Drosophila neuromuscular junction boutons, chiefly by controlling Rab35 GTPase activity. (Fly (Drosophila melanogaster dm6)) PubMed

 28792.

in Drosophila knocking down IDE in insulin-producing cells (IPCs) of the brain results in increased body weight and fecundity, decreased circulating sugar levels, and reduced lifespan [insulin-degrading enzyme (IDE)] (Fly (Drosophila melanogaster dm6)) PubMed

 28793.

The results define a presynaptic trafficking pathway mediated by SNX16, NWK, and the ESCRT complex that functions to control synaptic growth signaling at the interface between endosomal compartments.(sorting nexin 16 or SNX16) (Fly (Drosophila melanogaster dm6)) PubMed

 28794.

Mutant embryos exhibit fragmented or decondensed nuclei and accumulate higher levels of SUMO-conjugated proteins, suggesting a role for Dgrn in genome stability.[Dgrn protein (degringolade)]. (Fly (Drosophila melanogaster dm6)) PubMed

 28795.

PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition. [PAPI protein, drosophila] (Fly (Drosophila melanogaster dm6)) PubMed

 28796.

the homeobox gene lms is a new muscle identity gene that interacts with various previously-characterized muscle identity genes to regulate normal formation of embryonic lateral transverse muscles (Fly (Drosophila melanogaster dm6)) PubMed

 28797.

The expression of dAven in Xenopus egg extracts resulted in G2/M arrest that was comparable to that caused by human Aven.(daven protein) (Fly (Drosophila melanogaster dm6)) PubMed

 28798.

SIRT1, in complex with LSD1, has a role in developmental epigenetic gene repression and regulation. (Fly (Drosophila melanogaster dm6)) PubMed

 28799.

A model where EF-G1 acts as a retrograde signal from mitochondria to the nucleus to slow down cell proliferation if mitochondrial energy output is low.[EF-G1, drosophila melanogaster] (Fly (Drosophila melanogaster dm6)) PubMed

 28800.

QUASIMODO is a Novel GPI-anchored zona pellucida protein involved in light input to the Drosophila circadian clock. [Quasimodo - qsm - CG13432] (Fly (Drosophila melanogaster dm6)) PubMed

 28801.

In spite of the high expression of GGA in testes, knocking down its expression by >95% using transgenic RNAi fly lines did not affect male fertility. (Fly (Drosophila melanogaster dm6)) PubMed

 28802.

The Ndfip promotes their activity in Notch ubiquitination and internalization to the lysosomal lumen for degradation. (Fly (Drosophila melanogaster dm6)) PubMed

 28803.

the regulatory pathways of functions and dysfunctions of Drosophila dTDP (Fly (Drosophila melanogaster dm6)) PubMed

 28804.

The wst gene is essential for regulation of sperm release from female storage organs, maintenance of sperm efficiency for entry into eggs, and formation of the male pronucleus in the egg at fertilization. [wst - wasted] (Fly (Drosophila melanogaster dm6)) PubMed

 28805.

Erect Wing facilitates context-dependent Wnt/Wingless signaling by recruiting the cell-specific Armadillo-TCF adaptor Earthbound to chromatin.[ Earthbound 1 protein (ebd1); drosophila melanogaster] (Fly (Drosophila melanogaster dm6)) PubMed

 28806.

Different levels of the Tripartite motif protein, Anomalies in sensory axon patterning (Asap), regulate distinct axonal projections of Drosophila sensory neurons. [Anomalies in sensory axon patterning (Asap)] (Fly (Drosophila melanogaster dm6)) PubMed

 28807.

a structure and functional analysis of the hobo transposable element of Drosophila melanogaster (Fly (Drosophila melanogaster dm6)) PubMed

 28808.

Defhc1.1 functions as an inhibitor of neurite growth by finely tuning the microtubule cytoskeleton dynamics.[Defc1.1] (Fly (Drosophila melanogaster dm6)) PubMed

 28809.

Survivin is essential to target the chromosomal passenger complex (CPC), and the mitotic kinesin-like protein 1 orthologue Pavarotti (Pav) to the central spindle and equatorial cell cortex during anaphase in both larval neuroblasts and spermatocytes. (Fly (Drosophila melanogaster dm6)) PubMed

 28810.

[insomniac] Insomniac can physically associate with Cul3; reduction of Cul3 activity in neurons recapitulates the insomniac phenotype. (Fly (Drosophila melanogaster dm6)) PubMed

 28811.

Drosophila are driven by a molecular oscillator in which the E2F1 transcription factor promotes CycE expression and S-phase initiation, S-phase then activates the CRL4(CDT2) ubiquitin ligase, and this mediates the destruction of E2F1 [CRL4(CDT2)] (Fly (Drosophila melanogaster dm6)) PubMed

 28812.

The RORalpha is a p53 regulator that exerts its role in increased apoptosis via p53. (Nuclear Receptor ROR-alpha) (Fly (Drosophila melanogaster dm6)) PubMed

 28813.

Swim is a cofactor that promotes long-range Wg signaling in vivo by maintaining the solubility of Wg. [Secreted Wingless-interacting molecule (Swim)] (Fly (Drosophila melanogaster dm6)) PubMed

 28814.

(nonmuscle myosin type IIB) Diverse functions are identified for nonmuscle myosin type IIB in synaptic transmission, suggesting that this motor protein is an active contributor to the physiology of synaptic vesicle recruitment. (Fly (Drosophila melanogaster dm6)) PubMed

 28815.

Codepletion of Vhl with Mgr gives partial rescue of tubulin instability, monopolar spindle formation, and loss of centrosomes.[prefoldin] (Fly (Drosophila melanogaster dm6)) PubMed

 28816.

This study demonistrated that a novel role for Draper-II in inhibiting glial responses to neurodegeneration, and indicates that a balance of opposing Draper-I and Draper-II signaling events is essential to maintain glial sensitivity to brain injury. (Fly (Drosophila melanogaster dm6)) PubMed

 28817.

in vivo studies with Jarid2 mutants in flies demonstrate that among several histone modifications tested, only methylation of histone 3 at K27 (H3K27), the mark implemented by PRC2, was affected[Polycomb repressive complex 2] (Fly (Drosophila melanogaster dm6)) PubMed

 28818.

we identify here the Acyl Co-A synthetases pudgy as a transcriptional target of insulin signaling, and show that modulation of pudgy expression levels causes changes in steady-state lipid levels in the fly (Fly (Drosophila melanogaster dm6)) PubMed

 28819.

The cara mitad (cmi) gene encodes the previously undiscovered N-terminal region of the Drosophila homolog of MLL2, consisting of PHD and HMG domains and receptor-binding motifs. [cara mitad - cmi] (Fly (Drosophila melanogaster dm6)) PubMed

 28820.

three microRNAs from the Hox complex in Drosophila (miR-10-5p, miR-10-3p, miR-iab-4-5p) do not have significant effects during embryogenesis on expression of Hox genes with high confidence microRNAs target sites in the 3'UTR of their mRNAs[mirn10] (Fly (Drosophila melanogaster dm6)) PubMed

 28821.

aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila, including CG14207 [TDP25] (Fly (Drosophila melanogaster dm6)) PubMed

 28822.

we propose that -1 ribosomal frameshifting contributes to the toxicity associated with (exp)CAG repeats.[ATXN3] (Fly (Drosophila melanogaster dm6)) PubMed

 28823.

PATs function as part of an amino acid-sensing engine that drives mTORC1 activation from endosomal and lysosomal membranes [PAT1] (Fly (Drosophila melanogaster dm6)) PubMed

 28824.

the SMARCAL1 annealing helicase buffers fluctuations in gene expression and that alterations in gene expression contribute to the penetrance of SIOD. (Fly (Drosophila melanogaster dm6)) PubMed

 28825.

This study explored possible roles of the Dbp21E2 RNA helicase in rhodopsin maturation (Fly (Drosophila melanogaster dm6)) PubMed

 28826.

Gmd and Gmer have roles in rescue of Notch signaling in cells incapable of GDP-L-fucose synthesis by gap junction transfer of GDP-L-fucose in Drosophila [Gmd, Gmer] (Fly (Drosophila melanogaster dm6)) PubMed

 28827.

Caudal-related homeodomain proteins CDX1/2 bind to DNA replication-related element binding factor.[CDX1 protein, drosophila; CDX2 protein, drosophila] (Fly (Drosophila melanogaster dm6)) PubMed

 28828.

These findings define residues and regions within Shh that are necessary for its recognition as a substrate for Hhat-mediated palmitoylation.[SHH] (Fly (Drosophila melanogaster dm6)) PubMed

 28829.

Suggest that Slim (Kelch domain containing 10/KLHDC10) is an activator of ASK1, contributing to oxidative stress-induced cell death through the suppression PP5. (Fly (Drosophila melanogaster dm6)) PubMed

 28830.

We have revealed functional connections at the behavioral level (learning/memory) depending on the GDNF and LIMK1 brain expression and HSPs transduction that might provide targets for complex approaches for the neurodegenerative diseases treatment. (Fly (Drosophila melanogaster dm6)) PubMed

 28831.

A large-scale RNA interference screen in Drosophila was performed to identify modifiers of toxicity induced by expression of truncated Ataxin-3 containing a disease-causing polygutamine expansion.[Ataxin 3] (Fly (Drosophila melanogaster dm6)) PubMed

 28832.

p53-related protein kinase is required for PI3K/TOR pathway-dependent growth.[PRPK protein (nori-2 or p53-related protein kinase; drosophila melanogaster] (Fly (Drosophila melanogaster dm6)) PubMed

 28833.

miR-276a and DopR regulatory module in Drosophila that functions in distinct circuits for naive odor responses and conditioned odor memory. (Fly (Drosophila melanogaster dm6)) PubMed

 28834.

a novel protein complex comprising Mesh and Ssk has an important role in sSJ formation and in intestinal barrier function in Drosophila (Fly (Drosophila melanogaster dm6)) PubMed

 28835.

we show that two closely related proteins, Zasp66 and the newly identified Zasp67, are also required for adult Z-disc stability and are participating with Zasp52 in Z-disc assembly resulting in more severe, synergistic myofibril defects in double mutants (Fly (Drosophila melanogaster dm6)) PubMed

 28836.

Together with our results suggesting that DmRet and DmGfrl do not function in cis in Drosophila, which lacks GDNF ligands, these data imply that DmGfrl may be an evolutionarily ancient binding partner for NCAM/FasII. (Fly (Drosophila melanogaster dm6)) PubMed

 28837.

This study characterized the novel gene tank, a tumor suppressor homolog that promotes ethanol sensitivity in Drosophila (Fly (Drosophila melanogaster dm6)) PubMed

 28838.

[Clamp protein] CLAMP directly binds to the male-specific lethal (MSL) complex DNA recognition elements and is required for the recruitment of the MSL complex (Fly (Drosophila melanogaster dm6)) PubMed

 28839.

Oatp58Dc contributes to blood-brain barrier function by excluding organic anions from the Drosophila brain. [Oatp58] (Fly (Drosophila melanogaster dm6)) PubMed

 28840.

[Gtsf1] the double CHHC zinc finger protein gametocyte-specific factor 1 (Gtsf1) is an essential factor for Piwi-mediated transcriptional repression in Drosophila. (Fly (Drosophila melanogaster dm6)) PubMed

 28841.

TnaA physically interacts with the SUMO E2 conjugating enzyme Ubc9, and with the BRM complex subunit Osa.[TnaA] (Fly (Drosophila melanogaster dm6)) PubMed

 28842.

PRC2 plays an exquisite role in the determination of the oocyte fate by preventing its switching into an endoreplicative program.[PRC2] (Fly (Drosophila melanogaster dm6)) PubMed

 28843.

the WD40 repeat protein Riquiqui (Riq) and the DYRK-family kinase Minibrain (Mnb)are two regulators of the Drosophila melanogaster SWH pathway that function downstream of Dachsous intracellular domains (Fly (Drosophila melanogaster dm6)) PubMed

 28844.

Lig regulates cell proliferation during development in concert with Rin, Capr and FMR1. (Fly (Drosophila melanogaster dm6)) PubMed

 28845.

These results indicate that adiponectin receptor in insulin producing cells regulates insulin secretion and controls glucose and lipid metabolism in Drosophila melanogaster.[adiponectic receptor] (Fly (Drosophila melanogaster dm6)) PubMed

 28846.

reduction of Ataxin-7 protein results in loss of components from the SAGA complex. (Fly (Drosophila melanogaster dm6)) PubMed

 28847.

mTerf5 knockdown led to enhanced replication pausing at mTTF binding sites, a decrease in fragile replication intermediates containing single-stranded segments, and the disappearance of species containing segments of RNA/DNA hybrid (Fly (Drosophila melanogaster dm6)) PubMed

 28848.

Hsp104 suppressed toxicity of a C-terminal MJD fragment when expressed after the onset of PolyQ-induced degeneration, whereas Hsp70 was ineffective (Fly (Drosophila melanogaster dm6)) PubMed

 28849.

Ibf1 and Ibf2 are DNA-binding proteins that form hetero-oligomers to mediate CP190 binding to chromatin, and are necessary for insulator activity. [Ibf1, Ibf2] (Fly (Drosophila melanogaster dm6)) PubMed

 28850.

Sudestada1 (Sud1) is a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth. (Fly (Drosophila melanogaster dm6)) PubMed

 28851.

dZip1 and dZip2 are specific zinc transporters involved in dietary zinc absorption [Zip2] (Fly (Drosophila melanogaster dm6)) PubMed

 28852.

Rau forms a positive feedback loop important for counteracting the Sprouty negative feedback loop in differentiating photoreceptors. [Rau] (Fly (Drosophila melanogaster dm6)) PubMed

 28853.

PON1 has a protective role in anoxia-reoxygenation injury, and its expression in the CNS is sufficient and necessary to provide a 100% survival protection. (Fly (Drosophila melanogaster dm6)) PubMed

 28854.

As dATP8B is a member of the phospholipid flippase family of ATPases, our findings suggest a requirement for phospholipid asymmetry in the signalling of a specific family of chemoreceptor proteins (Fly (Drosophila melanogaster dm6)) PubMed

 28855.

The effect of H4 tail at lysine 16 acetylation on ISWI remodelling depends on the precise nature of the substrate.[Histone H4] (Fly (Drosophila melanogaster dm6)) PubMed

 28856.

Overexpression of Otk causes female sterility due to malformation of the oviduct, indicating that Otk and Otk2 are specifically involved in the sexually dimorphic development of the genital tract (Fly (Drosophila melanogaster dm6)) PubMed

 28857.

The Sdhaf4 mutant flies heterozygous for a strong loss-of-function mutation in SdhA or homozygous for a hypomorphic mutation in SdhB displayed reduced viability.(SDHAF4 protein) (Fly (Drosophila melanogaster dm6)) PubMed

 28858.

Tubulin folding cofactor D (TBCD) physically interacts with DScam. Neurons homozygous for the TBCD mutation displayed disruption of microtubules (Fly (Drosophila melanogaster dm6)) PubMed

 28859.

Banderuola (Bnd) is a novel regulator of asymmetric cell division (ACD). The data place Bnd at the top of the hierarchy of the factors involved in ACD, suggesting that its main function is mediating localization and function of Dlg tumor suppressor.[Bnd] (Fly (Drosophila melanogaster dm6)) PubMed

 28860.

The Nprl2/3 work in concert with the TORC1 inhibitors Tsc1/2 to fine tune TORC1 activity during oogenesis and that Tsc1 is a critical downstream effector of Akt1 in the female germline. [Nprl2 and Nprl3} (Fly (Drosophila melanogaster dm6)) PubMed

 28861.

The metal transporter ZIP13 supplies iron into the secretory pathway in Drosophila melanogaster.[Zip13] (Fly (Drosophila melanogaster dm6)) PubMed

 28862.

when Kkv and Exp/Reb are co-expressed in the ectoderm, they promote chitin deposition, even in tissues normally devoid of this polysaccharide. (Fly (Drosophila melanogaster dm6)) PubMed

 28863.

Genetic interactions at the cell-autonomous level, where glycolytic enzymes or Glo1 were manipulated in FASN mutant cells, revealed that this sugar-dependent size reduction is a direct consequence of MG-derived-AGE accumulation (Fly (Drosophila melanogaster dm6)) PubMed

 28864.

Corolla protein is a component of the synaptonemal complex. Corolla strongly interacts with Cona in yeast-2-hybrid system. (Fly (Drosophila melanogaster dm6)) PubMed

 28865.

Expression levels of estrogen-related receptor gene (ERR), ecdysone receptor gene (EcR) and Yolk protein receptor gene (YPR) were significantly changed by ethylparaben treatment. Female fruit flies are more sensitive to EP than males.[YPR] (Fly (Drosophila melanogaster dm6)) PubMed

 28866.

Grnd represents the first example of a TNFR that integrates signals from both Egr and apical polarity determinants to induce JNK-dependent cell death or tumour growth [Grindelwald=grnd] (Fly (Drosophila melanogaster dm6)) PubMed

 28867.

Drosophila KANK homolog (dKank) is essential for nephrocyte function. (Fly (Drosophila melanogaster dm6)) PubMed

 28868.

orcokinin B, CCHamide 1, and CCHamide 2 expression in Drosophila is reported.[Orcokinin B] (Fly (Drosophila melanogaster dm6)) PubMed

 28869.

[REPTOR-BP] REPTOR-BP plays critical roles in maintaining energy homeostasis and promoting animal survival upon nutrient restriction (Fly (Drosophila melanogaster dm6)) PubMed

 28870.

These results indicate that HIF-1alpha is required to restrain the NF-kappaB response, and thus prevents excessive and damaging pro-inflammatory responses.[NFKB] (Fly (Drosophila melanogaster dm6)) PubMed

 28871.

[FACT protein] CENP-A assembly by its loading factor, CAL1, requires RNAPII-mediated transcription of the underlying DNA. This transcription depends on the CAL1 binding partner FACT (Fly (Drosophila melanogaster dm6)) PubMed

 28872.

Pasiflora1 and Pasiflora2 are novel integral components of the septate junction.[Pasiflora1, Pasiflora2] (Fly (Drosophila melanogaster dm6)) PubMed

 28873.

Armless may promote Wg signaling by rescuing Armadillo from proteolytic degradation. [Armless] (Fly (Drosophila melanogaster dm6)) PubMed

 28874.

Oxygen Sensitivity of the Peptidylglycine alpha-Amidating Monooxygenase (PAM) in Neuroendocrine Cells [PAM] (Fly (Drosophila melanogaster dm6)) PubMed

 28875.

VGLUT2 mutations that block homeostatic potentiation do not alter homeostatic depression indicating that these are genetically separable processes. [VGLUT2] (Fly (Drosophila melanogaster dm6)) PubMed

 28876.

dDsk2 prevents dUbp8/Nonstop-dependent H2Bub1 deubiquitylation at promoters of dHP1c complex target genes and regulates RNA polymerase II pausing.[H2Bub1] (Fly (Drosophila melanogaster dm6)) PubMed

 28877.

Alpha-Synuclein overexpression reduced the synaptic transmission of cholinergic neurons by modulating the calcium channel currents in the projection neurons in the antennal lobe region of the brain, as well as the learning and memory ability of the flies. (Fly (Drosophila melanogaster dm6)) PubMed

 28878.

Suggest gammaH2AX may be a reliable biomarker for assessing muscle aging in Drosophila. (Fly (Drosophila melanogaster dm6)) PubMed

 28879.

these data suggest that SEPT9 protects actin filaments from depolymerization by cofilin and myosin and indicate a mechanism by which SEPT9 could maintain the integrity of growing and contracting actin filaments. [SEPT9] (Fly (Drosophila melanogaster dm6)) PubMed

 28880.

[Klf15] - critical for development and differentiation of nephrocytes (Fly (Drosophila melanogaster dm6)) PubMed

 28881.

Propose that MIGA proteins promote mitochondrial fusion by regulating mitochondrial phospholipid metabolism via MitoPLD. (Fly (Drosophila melanogaster dm6)) PubMed

 28882.

These observations imply that the main biological function of Ouib is to specifically regulate spookier transcription during Drosophila development. (Fly (Drosophila melanogaster dm6)) PubMed

 28883.

These transgenic Drosophila lines provide resources to dissect the pathways affected by DUX4-fl or FRG1 in a genetically tractable organism and may provide insight into pathogenic mechanisms in facioscapulohumeral muscular dystrophy.[DUX4] (Fly (Drosophila melanogaster dm6)) PubMed

 28884.

Our findings indicate that dGBA1b plays an important role in the metabolism of protein aggregates, but that the deleterious consequences of mutations in dGBA1b are largely independent of a-synuclein (Fly (Drosophila melanogaster dm6)) PubMed

 28885.

Functional loss of glucocerebrosidase promotes toxic conversion of alphaSyn via aberrant interactions between alphaSyn and their substrate glycolipids, leading to aggravation of alphaSyn-mediated neurodegeneration (glucocerebrosidase 1). (Fly (Drosophila melanogaster dm6)) PubMed

 28886.

Data suggest single G-box domain (14-20 antiparallel beta-strands) of CENPJ has stable but dynamic structure; CRAP forms multimers (in solution and in crystals) of elongated fibrils similar to amyloid fibrils. [REVIEW] [cenpj, centromere protein J] (Fly (Drosophila melanogaster dm6)) PubMed

 28887.

Prtl99C is a Drosophila sperm chromatin-associated protein that is essential for male fertility. (Fly (Drosophila melanogaster dm6)) PubMed

 28888.

Coupled with the prior finding that ZC3H14 is highly expressed in rodent hippocampal neurons[Zc3h14] (Fly (Drosophila melanogaster dm6)) PubMed

 28889.

Daughterless and Tcf4 are expressed in postmitotic neurons in Drosophila melanogaster and mice, respectively, where they function to restrict neurite branching and synapse formation in part by restricting the expression of the cell adhesion molecule Neurexin. (Fly (Drosophila melanogaster dm6)) PubMed

 28890.

Ddbt is recruited to telomeres and ensures that telomere-capping complexes are maintained through spermiogenesis and transmitted to offspring. (Fly (Drosophila melanogaster dm6)) PubMed

 28891.

a very long chain fatty-acyl-CoA reductase (FarO) and a putative lipid dehydrogenase/reductase (Spidey, also known as Kar) not only promote lipid droplet induction but also inhibit oenocyte growth. In the case of Spidey/Kar, we show that the growth suppression mechanism involves inhibition of the PI3K signaling pathway upstream of Akt activity (Fly (Drosophila melanogaster dm6)) PubMed

 28892.

lack of ChChd3 leads to inactivation of Hippo activity under normal development, which is also dependent on the transcriptional coactivator Yorkie (Yki). Furthermore, loss of ChChd3 induces oxidative stress and activates the JNK pathway. In addition, depletion of other mitochondrial fusion components, Opa1 or Marf, inactivates the Hippo pathway as well (Fly (Drosophila melanogaster dm6)) PubMed

 28893.

With two crosses, this technique converts existing GAL4 lines, including enhancer traps, into functional QF2 expressing lines. We used HACK to convert the most commonly-used GAL4 lines (labeling tissues such as neurons, fat, glia, muscle, and hemocytes) to QF2 lines. (Fly (Drosophila melanogaster dm6)) PubMed

 28894.

The exact position where the transposable elements are inserted matters, as they all showed highly conserved sequences but only two of the analyzed insertions provided alternative transcription start sites, and only the FBti0019985 insertion consistently affects CG18446 expression. (Fly (Drosophila melanogaster dm6)) PubMed

 28895.

Our work reveals that the major requirement for NuA4 in the cell cycle in vivo is to suppress an endogenous DNA damage response, which is required to coordinate proper S and G2 cell cycle progression with differentiation and cell cycle gene expression. (Fly (Drosophila melanogaster dm6)) PubMed

 28896.

NAi mediated depletion of YKT6 and VAMP3 in mammalian cells also blocks constitutive secretion suggesting that YKT6 has an evolutionarily conserved role in this process. The unexpected role of YKT6 in plasma membrane fusion may in part explain why RNAi and gene disruption studies have failed to produce the expected phenotypes in higher eukaryotes (Fly (Drosophila melanogaster dm6)) PubMed

 28897.

miR-263a downregulates the expression of epithelial sodium channel (ENaC) subunits in enterocytes (ECs) to maintain osmotic and intestinal stem cell homeostasis.[Enac] (Fly (Drosophila melanogaster dm6)) PubMed

 28898.

analysis of the role of Drosophila CNPYa and CNPYb in gp93 biology [CNPYa and CNPYb] (Fly (Drosophila melanogaster dm6)) PubMed

 28899.

PRC2 binding to the majority of Drosophila polycomb response elements depends on PRC1. [prc2] (Fly (Drosophila melanogaster dm6)) PubMed

 28900.

DDX3/Belle Exerts Its Function Outside of the Wnt/Wingless Signaling Pathway [DDX3] (Fly (Drosophila melanogaster dm6)) PubMed

 28901.

To characterize natural genetic variation in the IIS/TOR pathway, we used >250 recombinant inbred lines (RILs) derived from a multiparental mapping population, the Drosophila Synthetic Population Resource, to map transcript-level QTL of genes encoding 52 core IIS/TOR components in three different nutritional environments (Fly (Drosophila melanogaster dm6)) PubMed

 28902.

Functional analysis of iodotyrosine deiodinase from drosophila melanogaster (Fly (Drosophila melanogaster dm6)) PubMed

 28903.

Nardilysin (NRD1) is localized to mitochondria, where it recruits mitochondrial chaperones and assists in the folding of alpha-ketoglutarate dehydrogenase (OGDH), a rate-limiting enzyme in the Krebs cycle. Loss of Nrd1 or Ogdh leads to an increase in alpha-ketoglutarate, a substrate for OGDH, which in turn leads to mTORC1 activation and a subsequent reduction in autophagy. (Fly (Drosophila melanogaster dm6)) PubMed

 28904.

Inhibition of Nuak1 in fruit flies suppressed neurodegeneration in tau-expressing Drosophila. (Fly (Drosophila melanogaster dm6)) PubMed

 28905.

sideroflexin 3 (SFXN3) was found to be a mitochondrial protein localized to the inner mitochondrial membrane. (Fly (Drosophila melanogaster dm6)) PubMed

 28906.

LSM12 is an ATX2-associating factor crucial for sustaining circadian pacemaker neurons and locomotor activity. DDX6 forms complex contributing to 24 hr periodicity and high-amplitude rhythms in circadian behaviors in Drosophila. (Fly (Drosophila melanogaster dm6)) PubMed

 28907.

PRC2-dependent histone modification marks epialleles in transgenerational epigenetic inheritance. [PRC2] (Fly (Drosophila melanogaster dm6)) PubMed

 28908.

Ca2+ uptake in neurons with reduced SEPT7 requires Orai. [sep7] (Fly (Drosophila melanogaster dm6)) PubMed

 28909.

alpha2delta proteins reside at the extracellular face of presynaptic release sites throughout the nervous system, a site ideal for mediating rapid, transsynaptic homeostatic signaling in health and disease.[alpha2 delta3] (Fly (Drosophila melanogaster dm6)) PubMed

 28910.

In order to obtain independent evidence for the involvement of FITM2 in the human pathology, downregulation of the single Fitm ortholog, CG10671, in Drosophila melanogaster was pursued using RNA interference.[FITM2] (Fly (Drosophila melanogaster dm6)) PubMed

 28911.

Receptor Accessory Protein Like 1 (REEPL1) can promote spermatogenesis and is regulated by PHF7 in the spermatogonial stage. (Fly (Drosophila melanogaster dm6)) PubMed

 28912.

DmCSS was mainly secreted into the culture medium, although partially detected in Golgi. Consistent with these results, the N-terminal hydrophobic regions of AaCSS and TcCSS functioned as a signal peptide to render them soluble in the ER, while the N-terminus of DmCSS functioned as a membrane-spanning region of type II transmembrane proteins whose cytosolic KLK sequence functioned as an ER export signal (Fly (Drosophila melanogaster dm6)) PubMed

 28913.

Study found that phototransduction was quantitatively unaffected not only after IP3R-RNAi, but also in IP3R-null mutants; describes novel phenotypes in photoreceptors from flies expressing the transcription factor (Gal4) used to drive RNAi expression. Results indicate that IP3R plays no significant role in Drosophila phototransduction while emphasizing the need for caution when using Gal4 drivers. [Gal4] (Fly (Drosophila melanogaster dm6)) PubMed

 28914.

Ttk69 causes the histone deacetylation-mediated repression of tll via the interaction of Pits and Sin3A (Fly (Drosophila melanogaster dm6)) PubMed

 28915.

Dcf1 plays an important role in behavior induced by the mushroom body in Drosophila and the dentate gyrus (DG) in mice and provides novel insights into their functions. Dcf1 rescued the optogenetic suppression of behavior by halorhodopsin in transgenic animals. [Dcf1] (Fly (Drosophila melanogaster dm6)) PubMed

 28916.

Idh3b may be an apoptogenic factor that functions much like released cytochrome c in mammalian cells.[ldh3b] (Fly (Drosophila melanogaster dm6)) PubMed

 28917.

Loss of spermine synthase (SMS) in Drosophila recapitulates the pathological polyamine imbalance of SRS and causes survival defects and synaptic degeneration. SMS deficiency leads to excessive spermidine catabolism, which generates toxic metabolites that cause lysosomal defects and oxidative stress. Consequently, autophagy-lysosome flux and mitochondrial function are compromised in the Drosophila nervous system. (Fly (Drosophila melanogaster dm6)) PubMed

 28918.

The comprehensive pathological and molecular data generated through this study strongly validate the causal role of TREM2/TYROBP in driving molecular networks in Alzheimer's disease (AD) and AD-related phenotypes in flies.[TREM2, TRYOBP] (Fly (Drosophila melanogaster dm6)) PubMed

 28919.

missense variants in the BTB-domain-encoding region of RHOBTB2 as causative for a developmental and epileptic encephalopathy.[RHOBTB2] (Fly (Drosophila melanogaster dm6)) PubMed

 28920.

The authors demonstrate a conserved, motor-domain dependent function of the Kinesin-2/IFT-A complex in promoting nuclear translocation of beta-catenin. [kinesin-2] (Fly (Drosophila melanogaster dm6)) PubMed

 28921.

Coexpression of the chaperon HSP40 and HSP70 effectively rescues the effects of Atxn3-84Q, indicating that polyQ protein aggregation in glia is deleterious. Intriguingly, coexpression of wild-type Atxn3-27Q can also rescue BBB/BRB impairment, suggesting that normal polyQ protein may have a protective function. (Fly (Drosophila melanogaster dm6)) PubMed

 28922.

Consistent with the role of Crb in apical membrane growth, RNAi-mediated knockdown of Crb results in decreased apical surface growth of tracheal cells and impaired axial elongation of the dorsal trunk. We conclude that Apn is a novel regulator of tracheal tube expansion in larval tracheae, the function of which is mediated by Crb. (Fly (Drosophila melanogaster dm6)) PubMed

 28923.

We further provide data on the physical interaction of Narya, Nenya and Vilya, as assayed by the yeast two-hybrid system. Together these data support the view that all three RING finger domain-containing proteins function in the formation of meiotic DNA DSBs and in the process of crossing over. (Fly (Drosophila melanogaster dm6)) PubMed

 28924.

the balance of VGLUT2 expression is a crucial determinant of DA neuron survival; a Drosophila model demonstrates selective vulnerability of midbrain dopamine neurons [VGLUT2] (Fly (Drosophila melanogaster dm6)) PubMed

 28925.

The arginine-rich dipeptide repeats are toxic products from the C9orf72 repeat expansion mutations. Glycine-Arginine/Proline-Arginine with 36 repeats could lead to neurodegenerative phenotypes only when they were expressed in glutamatergic neurons, including motor neurons. They cause selective degeneration in glutamatergic neurons and revealed an NMDA receptor-dependent cell-autonomous excitotoxicity mechanism.C9orf72. (Fly (Drosophila melanogaster dm6)) PubMed

 28926.

This protein, which we named Veneno, associates directly with Ago3 in an sDMA-dependent manner and localizes in cytoplasmic foci reminiscent of piRNA processing granules of Drosophila. We propose that Veneno assembles a multi-protein complex for ping-pong dependent piRNA production from viral RNA (Fly (Drosophila melanogaster dm6)) PubMed

 28927.

Our findings on GPI-MT2 provide a mechanistic link between GPI anchor biosynthesis and protein trafficking in Drosophila [GPI MT2] (Fly (Drosophila melanogaster dm6)) PubMed

 28928.

This study showed that transgene overexpression of the cystathionine gamma-lyase (CSE) and CBS in Drosophila induce similar effects on stress-resistance and locomotor activity, however lifespan extending effect was revealed for CBS overexpression only.[CSE] (Fly (Drosophila melanogaster dm6)) PubMed

 28929.

heterozygosity for Enhancer of Polycomb [E(Pc)], a component of the Tip60 lysine acetyltransferase complex (also known as KAT5 in humans), significantly increased tumor burden in hop(Tum) animals. (Fly (Drosophila melanogaster dm6)) PubMed

 28930.

Our results reveal BCDIN3D's biological role in female fertility and its molecular role in defining miRNA and mRNA profiles in ovaries. (Fly (Drosophila melanogaster dm6)) PubMed

 28931.

This study determined the atomic structure of the Drosophila P element transposase strand transfer complex using cryo-EM. [P element transposase] (Fly (Drosophila melanogaster dm6)) PubMed

 28932.

Serum amyloid P component promotes formation of distinct aggregated lysozyme morphologies and reduces toxicity in Drosophila flies expressing human F57I lysozyme. [Serum amyloid P component] (Fly (Drosophila melanogaster dm6)) PubMed

 28933.

Poc1B interacts with Sas-6 during proximal centriole-like structure formation. (Fly (Drosophila melanogaster dm6)) PubMed

 28934.

Oskyddad - a human ABCA12 paralog-contributes to the waterproof barrier function of the cuticle in Drosophila melanogaster. Loss of Osy function provokes rapid desiccation. (Fly (Drosophila melanogaster dm6)) PubMed

 28935.

ZAF1 can bind to artificial DNA consisting of six reiterated consensus sites and form a functional regulatory element that supports distance interactions and functions as an insulator (ZAR1). (Fly (Drosophila melanogaster dm6)) PubMed

 28936.

The Sbf localizes to tubular, apical surfaces and associates with Rab35, where it promotes Rab GTP exchange. (Sbf protein) (Fly (Drosophila melanogaster dm6)) PubMed

 28937.

the dynamic instability of the kinesin-2 stalk could play a crucial role in maintaining its biological function.[Kinesin 2] (Fly (Drosophila melanogaster dm6)) PubMed

 28938.

identification of Hodor, an ionotropic receptor in enterocytes that sustains larval development, particularly in nutrient-scarce conditions; experiments in Xenopus oocytes and flies indicate that Hodor is a pH-sensitive, zinc-gated chloride channel that mediates a previously unrecognized dietary preference for zinc [Hodor] (Fly (Drosophila melanogaster dm6)) PubMed

 28939.

Kinesin associated protein, DmKAP, binding harnesses the C-terminal ends of the Drosophila kinesin-2 stalk heterodimer. (Fly (Drosophila melanogaster dm6)) PubMed

 28940.

Distinct RhoGEFs Activate Apical and Junctional Contractility under Control of G Proteins during Epithelial Morphogenesis. (Fly (Drosophila melanogaster dm6)) PubMed

 28941.

Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila. (Fly (Drosophila melanogaster dm6)) PubMed

 28942.

Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila. (Fly (Drosophila melanogaster dm6)) PubMed

 28943.

Neuronal-specific proteasome augmentation via Prosbeta5 overexpression extends lifespan and reduces age-related cognitive decline. (Fly (Drosophila melanogaster dm6)) PubMed

 28944.

DAnkrd49 and Bdbt act via Casein kinase Iepsilon to regulate planar polarity in Drosophila. (Fly (Drosophila melanogaster dm6)) PubMed

 28945.

hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its Aggregation. (Fly (Drosophila melanogaster dm6)) PubMed

 28946.

Loss of function in the Drosophila clock gene period results in altered intermediary lipid metabolism and increased susceptibility to starvation. (Fly (Drosophila melanogaster dm6)) PubMed

 28947.

Chromosome separation during Drosophila male meiosis I requires separase-mediated cleavage of the homolog conjunction protein UNO. (Fly (Drosophila melanogaster dm6)) PubMed

 28948.

The enzyme removes glutamyl or aspartyl residues from N-terminal acidic amino acid-containing peptides. [aminopeptidase] (Glycine max) PubMed

 28949.

The recovery of heat shock-released Ca(2+) in Ca(2+)-pectate reconstitution through PME activity is required for cell wall.[PME] remodelling during HS in soybean (Glycine max) PubMed

 28950.

The accumulation of CSN proteins might enhance the degradation of ubiquitinated proteins independent of hypoxia caused by flooding, thereby lowering their abundance during flooding stress. [CSN4 and CSN5] (Glycine max) PubMed

 28951.

miR156 regulates miR172 expression and controls the level of an AP2. The latter, either directly or indirectly, controls the expression of nonsymbiotic hemoglobin, which is essential for regulating the levels of nodulation.[miR156; miR172] (Glycine max) PubMed

 28952.

Isc is a dominant gene controlling seed coat impermeability [Isc] (Glycine max) PubMed

 28953.

Rpp6 is a Phakopsora pachyrhizi resistance allele protecting against soybean rust [Rpp6] (Glycine max) PubMed

 28954.

The soybean rust resistance gene in cultivar PI 567104B might be the same as the Rpp6 gene from cultivar PI 567102B. [Rpp6] (Glycine max) PubMed

 28955.

A novel rust resistance gene, Rpp7, was mapped to a 154-kb interval on chromosome 19 that is different from the genomic locations of any previously reported Rpp genes. [Rpp7] (Glycine max) PubMed

 28956.

Rag1 altered the movement of biotype 1 soybean aphid on soybean plants under greenhouse conditions. However, the spatial pattern of soybean aphid on resistant plants did not differ from that on susceptible plants under field conditions with naturally occurring aphids. [Rag1] (Glycine max) PubMed

 28957.

natural variation in promoter affects photoperiod control of flowering time and maturity - [GBP1] (Glycine max) PubMed

 28958.

the constitutive expression of PSK-gamma in Arabidopsis promotes the growth of vegetative organs as well as seeds.pPSK gamma] (Glycine max) PubMed

 28959.

Characterization of Soybean STAY-GREEN Genes in Susceptibility to Foliar Chlorosis of Sudden Death Syndrome. (Glycine max) PubMed

 28960.

A class B heat shock factor selected for during soybean domestication contributes to salt tolerance by promoting flavonoid biosynthesis. (Glycine max) PubMed

 28961.

Overexpression of GmNFYA5 confers drought tolerance to transgenic Arabidopsis and soybean plants. (Glycine max) PubMed

 28962.

Impaired folate binding of serine hydroxymethyltransferase 8 from soybean underlies resistance to the soybean cyst nematode. (Glycine max) PubMed

 28963.

1) TSS2 functions as a regulator of the extensive cross-talk between the ABA and ethylene signalling pathways. [TSS2] 2) TOS1 functions as a regulator of the extensive cross-talk between the ABA and ethylene signalling pathways. [TOS1] (Solanum lycopersicum) PubMed

 28964.

Od-2 is essential for the synthesis of diverse trichome-borne compounds.[Od-2] (Solanum lycopersicum) PubMed

 28965.

Of the two CKO isoforms that are naturally expressed in tomato, CKO43 and CKO37, only the expression of CKO37 was affected by Tat. CKO37. (Solanum lycopersicum) PubMed

 28966.

These results suggest that over expressing MhSnRK1 can increase both the carbon and nitrogen assimilation rate of the plant as well as regulate the development of tomato fruit. (SnRK1) (Solanum lycopersicum) PubMed

 28967.

Impaired root function of tos1 plants failed to meet transpirational water demand and resulted in shoot turgor loss, stomatal closure and growth inhibition.[Tos1] (Solanum lycopersicum) PubMed

 28968.

pmcd1 - mutation role in a general defect in cell plate formation, most probably caused by alterations in callose biosynthesis (Solanum lycopersicum) PubMed

 28969.

The expression of LeHY5, SIMYB12, and LeELIP was found to be higher in tomato fruits expressing InsP 5-ptase. [InsP 5-ptase] (Solanum lycopersicum) PubMed

 28970.

Our results suggest...that 7B-1 mutation impairs an element of blue light signaling pathway involved in stomatal opening. [7B-1] (Solanum lycopersicum) PubMed

 28971.

Data suggest that the microRNA156 (miR156) is involved in maintenance of the meristematic state of ovary tissues, thereby controlling initial steps of fleshy fruit development and determinacy: [mir-156] (Solanum lycopersicum) PubMed

 28972.

This is the first biological demonstration that Sw-5-mediated resistance is triggered by the Tomato spotted wilt virus cell-to-cell movement protein.[Sw-5b] (Solanum lycopersicum) PubMed

 28973.

These data provide novel insights into the interaction between SlAGO1s and miR168 in determining growth rate, phase change, leaf epinasty, fruit initiation and expansion, and other developmental processes in tomato.[miR168] (Solanum lycopersicum) PubMed

 28974.

negative regulator of arbuscule formation by hampering auxin perception in arbuscule-containing cells [miR393] (Solanum lycopersicum) PubMed

 28975.

miR858 was identified as a negative regulator of anthocyanin biosynthesis in tomato.[miR858] (Solanum lycopersicum) PubMed

 28976.

Data suggest that NLRP-IR-I2-NTP exhibits DNA-binding, nucleotide-binding, and ATPase activity in addition to nucleotide exchange activity. [NLRP-IR-I2-NTP, nucleotide-binding leucine-rich repeat immune receptor I-2 nucleotide transport protein] (Solanum lycopersicum) PubMed

 28977.

Avr2 is sufficient to induce I-2-mediated cell death, Avr2 and Six5 are both required for resistance.[I-2] (Solanum lycopersicum) PubMed

 28978.

The results of this study provide accountable evidence for the physiological and transcriptional regulation of the Cf-10-mediated resistance response to C. fulvum infection.[Cf-10] (Solanum lycopersicum) PubMed

 28979.

This study aimed to map and identify molecular marker tightly linked to the Sm gene for the use of marker-assisted selection in breeding.[Sm] (Solanum lycopersicum) PubMed

 28980.

These results reveal a cooperative regulation of tomato floral induction and flower development, integrating age cues (miR156 module) with GA responses and miR319-controlled pathways.[miR136, miR319] (Solanum lycopersicum) PubMed

 28981.

The data support a model in which Sl-SAUR69 represses auxin transport, thus generating auxin minima, which results in enhanced ethylene sensitivity.[SAUR69] (Solanum lycopersicum) PubMed

 28982.

The results provide new insight into the Cf-mediated mechanism of resistance to C. fulvum, especially the unique characteristics of Cf-16 tomato in response to this fungus. [cf-16] (Solanum lycopersicum) PubMed

 28983.

cold acclimation at 12 degrees C induced the transcripts of GLR3.3 and GLR3.5 with increased tolerance against a subsequent chilling at 4 degrees C.[GLR3.3, GLR3.5] (Solanum lycopersicum) PubMed

 28984.

PYL9 is involved in the regulation of ABA signaling during tomato fruit ripening. (Solanum lycopersicum) PubMed

 28985.

In-depth proteome analysis reveals multiple pathways involved in tomato SlMPK1-mediated high-temperature responses. (Solanum lycopersicum) PubMed

 28986.

Deficiency of GDP-L-galactose phosphorylase, an enzyme required for ascorbic acid synthesis, reduces tomato fruit yield. (Solanum lycopersicum) PubMed

 28987.

Suppression of RNA-dependent RNA polymerase 6 in tomatoes allows potato spindle tuber viroid to invade basal part but not apical part including pluripotent stem cells of shoot apical meristem. (Solanum lycopersicum) PubMed

 28988.

Two promoter regions confer heat-induced activation of SlDREBA4 in Solanum lycopersicum. (Solanum lycopersicum) PubMed

 28989.

Cold-regulated gene LeCOR413PM2 confers cold stress tolerance in tomato plants. (Solanum lycopersicum) PubMed

 28990.

CRISPR/Cas9-mediated mutagenesis of CAROTENOID CLEAVAGE DIOXYGENASE 8 in tomato provides resistance against the parasitic weed Phelipanche aegyptiaca. (Solanum lycopersicum) PubMed

 28991.

The Tomato Metallocarboxypeptidase Inhibitor I, which Interacts with a Heavy Metal-Associated Isoprenylated Protein, Is Implicated in Plant Response to Cadmium. (Solanum lycopersicum) PubMed

 28992.

The tomato receptor CuRe1 senses a cell wall protein to identify Cuscuta as a pathogen. (Solanum lycopersicum) PubMed

 28993.

FIS1 encodes a GA2-oxidase that regulates fruit firmness in tomato. (Solanum lycopersicum) PubMed

 28994.

Tomato roots have a functional silicon influx transporter but not a functional silicon efflux transporter. (Solanum lycopersicum) PubMed

 28995.

SlSNAT Interacts with HSP40, a Molecular Chaperone, to Regulate Melatonin Biosynthesis and Promote Thermotolerance in Tomato. (Solanum lycopersicum) PubMed

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